![]() |
![]() |
![]() 3D structures of proteins and compounds related to Coronavirus SARS-CoV-2 |
![]() |
![]() |
AC | ID | length (amino acids) |
Number of 3D homologues |
short name | full name |
![]() |
AP3A_SARS2 | 275 | 12 | ORF3a; | ORF3a protein; Accessory protein 3a;Protein 3a;Protein U274;Protein X1; |
![]() |
NCAP_SARS2 | 419 | 240 | N; NC ;Protein N ; | Nucleoprotein ; Nucleocapsid protein ; |
![]() |
NS6_SARS2 | 61 | 0 | ORF6; ns6; | ORF6 protein; Accessory protein 6;Non-structural protein 6;Protein X3; |
![]() |
NS7A_SARS2 | 121 | 4 | ORF7a; | ORF7a protein; Accessory protein 7a;Protein U122;Protein X4; |
![]() |
NS7B_SARS2 | 43 | 0 | ORF7b; | ORF7b protein; Accessory protein 7b; |
![]() |
NS8_SARS2 | 121 | 9 | ORF8; ns8; | ORF8 protein; Non-structural protein 8; |
![]() |
ORF3B_SARS2 | 22 | 0 | ORF3b; | Putative ORF3b protein ; |
![]() |
ORF3C_SARS2 | 41 | 0 | ORF3c; ORF3h; | ORF3c protein ; ORF3h protein ; |
![]() |
ORF3D_SARS2 | 57 | 0 | Putative ORF3d protein ; | |
![]() |
ORF9B_SARS2 | 97 | 20 | ORF9b; | ORF9b protein; Accessory protein 9b;ORF-9b;Protein 9b; |
![]() |
ORF9C_SARS2 | 73 | 0 | ORF9c; ORF14; | Putative ORF9c protein ; Uncharacterized protein 14; |
![]() |
R1AB_SARS2 | 7096 | 1500 | pp1ab; | Replicase polyprotein 1ab; ORF1ab polyprotein; |
![]() |
R1A_SARS2 | 4405 | 1500 | pp1a; | Replicase polyprotein 1a; ORF1a polyprotein; |
![]() |
SPIKE_SARS2 | 1273 | 1500 | S glycoprotein ; | Spike glycoprotein ; E2 ;Peplomer protein ; |
![]() |
VEMP_SARS2 | 75 | 11 | E;sM protein ; | Envelope small membrane protein ; |
![]() |
VME1_SARS2 | 222 | 12 | M; | Membrane protein ; E1 glycoprotein ;Matrix glycoprotein ;Membrane glycoprotein ; |
![]() |
AP3A_SARS | 274 | 12 | ORF3a protein; Accessory protein 3a;Protein 3a;Protein U274;Protein X1; | |
![]() |
NCAP_SARS | 422 | 241 | NC ;Protein N ; | Nucleoprotein ; Nucleocapsid protein ; |
![]() |
NS3B_SARS | 154 | 0 | ns3b; | ORF3b protein; Accessory protein 3b;Non-structural protein 3b;Protein X2; |
![]() |
NS6_SARS | 63 | 0 | ORF6; ns6; | ORF6 protein; Accessory protein 6;Non-structural protein 6;Protein X3; |
![]() |
NS7A_SARS | 122 | 4 | ORF7a protein; Accessory protein 7a;Protein U122;Protein X4; | |
![]() |
NS7B_SARS | 44 | 0 | ns7b; | Protein non-structural 7b; Accessory protein 7b; |
![]() |
NS8A_SARS | 39 | 0 | ns8a; | ORF8a protein; Accessory protein 8a;Protein non-structural 8a; |
![]() |
NS8B_SARS | 84 | 0 | ns8b; | ORF8b protein; Accessory protein 8b;Non-structural protein 8b; |
![]() |
ORF9B_SARS | 98 | 20 | ORF9b protein; Accessory protein 9b;ORF-9b;Protein 9b; | |
![]() |
R1AB_SARS | 7073 | 1500 | pp1ab; | Replicase polyprotein 1ab; ORF1ab polyprotein; |
![]() |
R1A_SARS | 4382 | 1500 | pp1a; | Replicase polyprotein 1a; ORF1a polyprotein; |
![]() |
SPIKE_SARS | 1255 | 1500 | S glycoprotein ; | Spike glycoprotein ; E2 ;Peplomer protein ; |
![]() |
VEMP_SARS | 76 | 11 | E protein ;sM protein ; | Envelope small membrane protein ; |
![]() |
VME1_SARS | 221 | 12 | M protein ; | Membrane protein ; E1 glycoprotein ;Matrix glycoprotein ;Membrane glycoprotein ; |
![]() |
Y14_SARS | 70 | 0 | Uncharacterized protein 14; | |
![]() |
ACE2_HUMAN | 805 | 509 | ACEH ;ACE-related carboxypeptidase; | Angiotensin-converting enzyme 2; Angiotensin-converting enzyme homolog ;Angiotensin-converting enzyme-related carboxypeptidase ;Metalloprotease MPROT15 {ECO:0000303|Ref.6}; |
![]() |
AGTR1_HUMAN | 359 | 825 | AT1 receptor ; | Type-1 angiotensin II receptor ; AT1AR ;AT1BR;Angiotensin II type-1 receptor ; |
![]() |
ANO6_HUMAN | 910 | 103 | SCAN channel; | Anoctamin-6 ; Small-conductance calcium-activated nonselective cation channel;Transmembrane protein 16F; |
![]() |
APOE_HUMAN | 317 | 39 | Apo-E; | Apolipoprotein E ; |
![]() |
ARL8B_HUMAN | 186 | 1473 | ADP-ribosylation factor-like protein 8B ; ADP-ribosylation factor-like protein 10C;Novel small G protein indispensable for equal chromosome segregation 1; | |
![]() |
ASM_HUMAN | 631 | 32 | aSMase; | Sphingomyelin phosphodiesterase ; Acid sphingomyelinase {ECO:0000303|PubMed:25339683, ECO:0000303|PubMed:27349982, ECO:0000303|PubMed:33163980}; |
![]() |
BASI_HUMAN | 385 | 48 | EMMPRIN;HAb18G ;TCSF; | Basigin ; 5F7;Collagenase stimulatory factor;Extracellular matrix metalloproteinase inducer;Hepatoma-associated antigen ;Leukocyte activation antigen M6;OK blood group antigen;Tumor cell-derived collagenase stimulatory factor; |
![]() |
BMAL1_HUMAN | 626 | 160 | bHLHe5; | Basic helix-loop-helix ARNT-like protein 1 ; Aryl hydrocarbon receptor nuclear translocator-like protein 1;Basic-helix-loop-helix-PAS protein MOP3;Brain and muscle ARNT-like 1;Class E basic helix-loop-helix protein 5;Member of PAS protein 3;PAS domain-containing protein 3;bHLH-PAS protein JAP3; |
![]() |
BST2_HUMAN | 180 | 47 | BST-2; | Bone marrow stromal antigen 2; HM1.24 antigen;Tetherin; |
![]() |
C2TA_HUMAN | 1130 | 68 | CIITA ; | MHC class II transactivator ; |
![]() |
CATL1_HUMAN | 333 | 810 | MEP; | Procathepsin L ; Cathepsin L1 ;Major excreted protein; |
![]() |
CH25H_HUMAN | 272 | 0 | h25OH; | Cholesterol 25-hydroxylase ; Cholesterol 25-monooxygenase; |
![]() |
DDX1_HUMAN | 740 | 826 | DBP-RB; | ATP-dependent RNA helicase DDX1; DEAD box protein 1;DEAD box protein retinoblastoma; |
![]() |
RIGI_HUMAN | 925 | 205 | RLR-1;RIG-1;RIG-I; | Antiviral innate immune response receptor RIG-I ; ATP-dependent RNA helicase DDX58 ;DEAD box protein 58;RIG-I-like receptor 1;RNA sensor RIG-I ;Retinoic acid-inducible gene 1 protein;Retinoic acid-inducible gene I protein; |
![]() |
DHX58_HUMAN | 678 | 217 | RLR-3;RLR; | ATP-dependent RNA helicase DHX58 ; ATP-dependent helicase LGP2 ;Protein D11Lgp2 homolog;RIG-I-like receptor 3;RIG-I-like receptor LGP2; |
![]() |
EF1A1_HUMAN | 462 | 449 | EF-1-alpha-1; EF-Tu;eEF1A-1; | Elongation factor 1-alpha 1; Elongation factor Tu;Eukaryotic elongation factor 1 A-1;Leukocyte receptor cluster member 7; |
![]() |
FAS_HUMAN | 2511 | 848 | Fatty acid synthase; Type I fatty acid synthase; | |
![]() |
FURIN_HUMAN | 794 | 252 | PACE; | Furin ; Dibasic-processing enzyme;Paired basic amino acid residue-cleaving enzyme; |
![]() |
FYV1_HUMAN | 2098 | 451 | Phosphatidylinositol 3-phosphate 5-kinase; PIPkin-III;Type III PIP kinase; | 1-phosphatidylinositol 3-phosphate 5-kinase ; FYVE finger-containing phosphoinositide kinase;PIKfyve;Phosphatidylinositol 3-phosphate 5-kinase type III;Serine-protein kinase PIKFYVE; |
![]() |
HG2A_HUMAN | 296 | 35 | Ii; | HLA class II histocompatibility antigen gamma chain ; HLA-DR antigens-associated invariant chain;Ia antigen-associated invariant chain; |
![]() |
HIF1A_HUMAN | 826 | 162 | HIF-1-alpha ;HIF1-alpha ; bHLHe78; | Hypoxia-inducible factor 1-alpha ; ARNT-interacting protein;Basic-helix-loop-helix-PAS protein MOP1 ;Class E basic helix-loop-helix protein 78;Member of PAS protein 1 ;PAS domain-containing protein 8; |
![]() |
HLAA_HUMAN | 365 | 1500 | HLA-A; | HLA class I histocompatibility antigen, A alpha chain; Human leukocyte antigen A; |
![]() |
HLAB_HUMAN | 362 | 1500 | HLA-B; | HLA class I histocompatibility antigen, B alpha chain; Human leukocyte antigen B; |
![]() |
HLAE_HUMAN | 358 | 1500 | HLA class I histocompatibility antigen, alpha chain E; MHC class I antigen E; | |
![]() |
HMGB1_HUMAN | 215 | 93 | HMG-1; | High mobility group protein B1; High mobility group protein 1; |
![]() |
I17RA_HUMAN | 866 | 28 | IL-17 receptor A;IL-17RA; | Interleukin-17 receptor A ; CDw217; |
![]() |
I17RC_HUMAN | 791 | 6 | IL-17 receptor C;IL-17RC; IL17Rhom;IL-17RL; | Interleukin-17 receptor C; Interleukin-17 receptor homolog;Interleukin-17 receptor-like protein;ZcytoR14; |
![]() |
IFIH1_HUMAN | 1025 | 297 | CADM-140 autoantigen;Helicard;MDA-5;RLR-2; | Interferon-induced helicase C domain-containing protein 1 ; Clinically amyopathic dermatomyositis autoantigen 140 kDa;Helicase with 2 CARD domains;Interferon-induced with helicase C domain protein 1;Melanoma differentiation-associated protein 5;Murabutide down-regulated protein;RIG-I-like receptor 2;RNA helicase-DEAD box protein 116; |
![]() |
IFM1_HUMAN | 125 | 0 | DSPA2a; | Interferon-induced transmembrane protein 1 ; Dispanin subfamily A member 2a;Interferon-induced protein 17;Interferon-inducible protein 9-27;Leu-13 antigen; |
![]() |
IFM2_HUMAN | 132 | 0 | DSPA2c; | Interferon-induced transmembrane protein 2 ; Dispanin subfamily A member 2c;Interferon-inducible protein 1-8D; |
![]() |
IFM3_HUMAN | 133 | 0 | DSPA2b; | Interferon-induced transmembrane protein 3 ; Dispanin subfamily A member 2b;Interferon-inducible protein 1-8U; |
![]() |
IL17F_HUMAN | 163 | 87 | IL-17F; | Interleukin-17F; Cytokine ML-1; |
![]() |
IL17_HUMAN | 155 | 81 | IL-17;IL-17A; CTLA-8; | Interleukin-17A; Cytotoxic T-lymphocyte-associated antigen 8; |
![]() |
IL6RA_HUMAN | 468 | 73 | IL-6 receptor subunit alpha;IL-6R subunit alpha;IL-6R-alpha;IL-6RA; gp80; | Interleukin-6 receptor subunit alpha ; IL-6R 1;Membrane glycoprotein 80; |
![]() |
IL6RB_HUMAN | 918 | 130 | IL-6 receptor subunit beta;IL-6R subunit beta;IL-6R-beta;IL-6RB; gp130 ; | Interleukin-6 receptor subunit beta ; CDw130;Interleukin-6 signal transducer;Membrane glycoprotein 130;Oncostatin-M receptor subunit alpha; |
![]() |
IL6_HUMAN | 212 | 20 | IL-6; BSF-2;CDF;IFN-beta-2; | Interleukin-6 ; B-cell stimulatory factor 2;CTL differentiation factor;Hybridoma growth factor;Interferon beta-2; |
![]() |
IMA1_HUMAN | 529 | 460 | Importin subunit alpha-1 ; Karyopherin subunit alpha-2;RAG cohort protein 1;SRP1-alpha; | |
![]() |
INAR1_HUMAN | 557 | 46 | IFN-R-1;IFN-alpha/beta receptor 1; CRF2-1; | Interferon alpha/beta receptor 1; Cytokine receptor class-II member 1;Cytokine receptor family 2 member 1;Type I interferon receptor 1; |
![]() |
INAR2_HUMAN | 515 | 12 | IFN-R-2;IFN-alpha binding protein;IFN-alpha/beta receptor 2; | Interferon alpha/beta receptor 2; Interferon alpha binding protein;Type I interferon receptor 2; |
![]() |
IRF3_HUMAN | 427 | 77 | IRF-3 ; | Interferon regulatory factor 3 {ECO:0000303|PubMed:9566918, ECO:0000303|PubMed:9803267}; |
![]() |
IRF5_HUMAN | 498 | 79 | IRF-5 ; | Interferon regulatory factor 5 ; |
![]() |
IRF7_HUMAN | 503 | 77 | IRF-7; | Interferon regulatory factor 7; |
![]() |
ISG15_HUMAN | 165 | 1453 | IP17;hUCRP; | Ubiquitin-like protein ISG15; Interferon-induced 15 kDa protein;Interferon-induced 17 kDa protein;Ubiquitin cross-reactive protein; |
![]() |
ITAL_HUMAN | 1170 | 387 | LFA-1A; | Integrin alpha-L ; CD11 antigen-like family member A;Leukocyte adhesion glycoprotein LFA-1 alpha chain;Leukocyte function-associated molecule 1 alpha chain; |
![]() |
KLRD1_HUMAN | 179 | 583 | Natural killer cells antigen CD94; KP43;Killer cell lectin-like receptor subfamily D member 1;NK cell receptor; | |
![]() |
LY6E_HUMAN | 131 | 0 | Ly-6E; RIG-E;SCA-2;TSA-1; | Lymphocyte antigen 6E ; Retinoic acid-induced gene E protein;Stem cell antigen 2;Thymic shared antigen 1; |
![]() |
MAVS_HUMAN | 540 | 46 | MAVS ; Cardif ;IPS-1;VISA; | Mitochondrial antiviral-signaling protein ; CARD adapter inducing interferon beta ;Interferon beta promoter stimulator protein 1;Putative NF-kappa-B-activating protein 031N;Virus-induced-signaling adapter; |
![]() |
MTA70_HUMAN | 580 | 139 | hMETTL3 ;MT-A70; | N6-adenosine-methyltransferase catalytic subunit ; Methyltransferase-like protein 3 ;N6-adenosine-methyltransferase 70 kDa subunit; |
![]() |
MYD88_HUMAN | 296 | 61 | Myeloid differentiation primary response protein MyD88 ; | |
![]() |
NEMO_HUMAN | 419 | 46 | NEMO ; IKKAP1;I-kappa-B kinase subunit gamma;IKK-gamma;IKKG;IkB kinase subunit gamma; | NF-kappa-B essential modulator ; FIP-3;IkB kinase-associated protein 1;Inhibitor of nuclear factor kappa-B kinase subunit gamma;NF-kappa-B essential modifier; |
![]() |
NEU2_HUMAN | 164 | 29 | Vasopressin-neurophysin 2-copeptin; AVP-NPII; | |
![]() |
NF2L2_HUMAN | 605 | 12 | NF-E2-related factor 2 ;NFE2-related factor 2 ;Nrf-2 ; | Nuclear factor erythroid 2-related factor 2 ; HEBP1;Nuclear factor, erythroid derived 2, like 2 {ECO:0000303|PubMed:33009401, ECO:0000303|PubMed:7937919}; |
![]() |
NHRF1_HUMAN | 358 | 318 | NHERF-1; EBP50; | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 ; Ezrin-radixin-moesin-binding phosphoprotein 50;Regulatory cofactor of Na(+)/H(+) exchanger;Sodium-hydrogen exchanger regulatory factor 1;Solute carrier family 9 isoform A3 regulatory factor 1; |
![]() |
NKG2A_HUMAN | 233 | 409 | NKG2-A/NKG2-B type II integral membrane protein; CD159 antigen-like family member A;NK cell receptor A;NKG2-A/B-activating NK receptor; | |
![]() |
NLRP1_HUMAN | 1473 | 247 | NACHT, LRR and PYD domains-containing protein 1 ; Caspase recruitment domain-containing protein 7;Death effector filament-forming ced-4-like apoptosis protein ;Nucleotide-binding domain and caspase recruitment domain; | |
![]() |
NLRP3_HUMAN | 1036 | 174 | CLR1.1 ; | NACHT, LRR and PYD domains-containing protein 3 ; Angiotensin/vasopressin receptor AII/AVP-like;Caterpiller protein 1.1 ;Cold-induced autoinflammatory syndrome 1 protein ;Cryopyrin ;PYRIN-containing APAF1-like protein 1 ; |
![]() |
NRP1_HUMAN | 923 | 224 | Neuropilin-1 ; Vascular endothelial cell growth factor 165 receptor; | |
![]() |
NUP98_HUMAN | 1817 | 207 | Nuclear pore complex protein Nup98-Nup96 ; | |
![]() |
OAS1_HUMAN | 400 | 13 | (2-5')oligo(A) synthase 1;2-5A synthase 1; | 2'-5'-oligoadenylate synthase 1; E18/E16;p46/p42 OAS; |
![]() |
PAIP1_HUMAN | 479 | 8 | PABP-interacting protein 1;PAIP-1;Poly(A)-binding protein-interacting protein 1; | Polyadenylate-binding protein-interacting protein 1 ; |
![]() |
PALS1_HUMAN | 675 | 202 | Protein PALS1 ; MAGUK p55 subfamily member 5;Membrane protein, palmitoylated 5 ;Protein associated with Lin-7 1 {ECO:0000303|PubMed:12527193, ECO:0000312|HGNC:HGNC:18669}; | |
![]() |
PHB1_HUMAN | 272 | 1 | Prohibitin 1 ; | |
![]() |
PHB2_HUMAN | 299 | 1 | Prohibitin-2; B-cell receptor-associated protein BAP37;D-prohibitin;Repressor of estrogen receptor activity; | |
![]() |
PK3C3_HUMAN | 887 | 522 | PI3-kinase type 3;PI3K type 3;PtdIns-3-kinase type 3; | Phosphatidylinositol 3-kinase catalytic subunit type 3; Phosphatidylinositol 3-kinase p100 subunit;Phosphoinositide-3-kinase class 3;hVps34; |
![]() |
PPIA_HUMAN | 165 | 593 | PPIase A; | Peptidyl-prolyl cis-trans isomerase A; Cyclophilin A;Cyclosporin A-binding protein;Rotamase A; |
![]() |
RAB7A_HUMAN | 207 | 1500 | Ras-related protein Rab-7a ; | |
![]() |
S10A8_HUMAN | 93 | 428 | CFAG;MRP-8;p8; | Protein S100-A8 ; Calgranulin-A;Calprotectin L1L subunit;Cystic fibrosis antigen;Leukocyte L1 complex light chain;Migration inhibitory factor-related protein 8;S100 calcium-binding protein A8;Urinary stone protein band A; |
![]() |
SGTA_HUMAN | 313 | 289 | UBP; | Small glutamine-rich tetratricopeptide repeat-containing protein alpha; Alpha-SGT;Vpu-binding protein; |
![]() |
SMAD3_HUMAN | 425 | 91 | MAD homolog 3;Mad3;Mothers against DPP homolog 3;hMAD-3; SMAD 3;Smad3;hSMAD3; | Mothers against decapentaplegic homolog 3; JV15-2;SMAD family member 3; |
![]() |
SNP29_HUMAN | 258 | 14 | SNAP-29 ; | Synaptosomal-associated protein 29 ; Soluble 29 kDa NSF attachment protein ;Vesicle-membrane fusion protein SNAP-29; |
![]() |
STX17_HUMAN | 302 | 9 | Syntaxin-17 ; | |
![]() |
TBK1_HUMAN | 729 | 1500 | Serine/threonine-protein kinase TBK1 ; NF-kappa-B-activating kinase ;T2K;TANK-binding kinase 1 ; | |
![]() |
TCAM1_HUMAN | 712 | 11 | TICAM-1; MyD88-3;TIR domain-containing adapter protein inducing IFN-beta; | TIR domain-containing adapter molecule 1; Proline-rich, vinculin and TIR domain-containing protein B;Putative NF-kappa-B-activating protein 502H;Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta; |
![]() |
TLR3_HUMAN | 904 | 792 | Toll-like receptor 3 ; | |
![]() |
TLR7_HUMAN | 1049 | 703 | Toll-like receptor 7 ; | |
![]() |
TLR8_HUMAN | 1041 | 594 | Toll-like receptor 8 ; | |
![]() |
TM41B_HUMAN | 291 | 0 | Transmembrane protein 41B ; Protein stasimon ; | |
![]() |
TMPS2_HUMAN | 492 | 1500 | Transmembrane protease serine 2 ; Serine protease 10 ; | |
![]() |
TMPS4_HUMAN | 437 | 1500 | CAPH2;MT-SP2; | Transmembrane protease serine 4 ; Channel-activating protease 2;Membrane-type serine protease 2; |
![]() |
TOM70_HUMAN | 608 | 168 | Mitochondrial import receptor subunit TOM70 ; Mitochondrial precursor proteins import receptor;Translocase of outer membrane 70 kDa subunit;Translocase of outer mitochondrial membrane protein 70 ; | |
![]() |
TPC2_HUMAN | 752 | 147 | Two pore channel protein 2; Two pore calcium channel protein 2; | |
![]() |
TYK2_HUMAN | 1187 | 1500 | Non-receptor tyrosine-protein kinase TYK2; | |
![]() |
V1BR_HUMAN | 424 | 534 | V1bR; | Vasopressin V1b receptor ; AVPR V1b;AVPR V3;Antidiuretic hormone receptor 1b;Vasopressin V3 receptor; |
![]() |
VAMP8_HUMAN | 100 | 50 | VAMP-8 ; EDB ; | Vesicle-associated membrane protein 8 ; Endobrevin ; |
![]() |
VPS39_HUMAN | 886 | 4 | hVam6p; | Vam6/Vps39-like protein ; TRAP1-like protein; |
![]() |
VPS41_HUMAN | 854 | 0 | Vacuolar protein sorting-associated protein 41 homolog; S53; | |
![]() |
ZDH20_HUMAN | 365 | 10 | DHHC20 ; | Palmitoyltransferase ZDHHC20 ; Acyltransferase ZDHHC20 ;DHHC domain-containing cysteine-rich protein 20 ;Zinc finger DHHC domain-containing protein 20 ; |
![]() |
ZDHC8_HUMAN | 765 | 10 | DHHC-8 ; | Palmitoyltransferase ZDHHC8 ; Zinc finger DHHC domain-containing protein 8 ;Zinc finger protein 378; |
![]() |
ZDHC9_HUMAN | 364 | 10 | DHHC-9;DHHC9; | Palmitoyltransferase ZDHHC9; Zinc finger DHHC domain-containing protein 9;Zinc finger protein 379;Zinc finger protein 380; |
protein_id | length (amino acids) |
Number of 3D homologues |
product | gene | note |
![]() |
7096 | 1500 | 2'-O-ribose methyltransferase | orf1ab | pp1ab; translated by -1 ribosomal frameshift |
![]() |
180 | 28 | leader protein | nsp1; produced by both pp1a and pp1ab | |
![]() |
638 | 8 | nsp2 | produced by both pp1a and pp1ab | |
![]() |
1945 | 1222 | nsp3 | former nsp1; conserved domains are: N-terminal | |
![]() |
500 | 9 | nsp4 | nsp4B_TM; contains transmembrane domain 2 (TM2); | |
![]() |
306 | 1500 | 3C-like proteinase | nsp5A_3CLpro and nsp5B_3CLpro; main proteinase | |
![]() |
290 | 0 | nsp6 | nsp6_TM; putative transmembrane domain; produced by | |
![]() |
83 | 87 | nsp7 | produced by both pp1a and pp1ab | |
![]() |
198 | 133 | nsp8 | produced by both pp1a and pp1ab | |
![]() |
113 | 60 | nsp9 | ssRNA-binding protein; produced by both pp1a and | |
![]() |
139 | 143 | nsp10 | nsp10_CysHis; formerly known as growth-factor-like | |
![]() |
932 | 60 | RNA-dependent RNA polymerase | nsp12; NiRAN and RdRp; produced by pp1ab only | |
![]() |
601 | 164 | helicase | nsp13_ZBD, nsp13_TB, and nsp_HEL1core; zinc-binding | |
![]() |
527 | 91 | 3'-to-5' exonuclease | nsp14A2_ExoN and nsp14B_NMT; produced by pp1ab | |
![]() |
346 | 163 | endoRNAse | nsp15-A1 and nsp15B-NendoU; produced by pp1ab only | |
![]() |
298 | 62 | 2'-O-ribose methyltransferase | nsp16_OMT; 2'-o-MT; produced by pp1ab only | |
![]() |
4405 | 1500 | nsp11 | orf1ab | pp1a |
![]() |
13 | 0 | nsp11 | produced by pp1a only | |
![]() |
1273 | 1500 | surface glycoprotein | S | structural protein; spike protein |
![]() |
275 | 12 | ORF3a protein | ORF3a | |
![]() |
75 | 11 | envelope protein | E | ORF4; structural protein; E protein |
![]() |
222 | 12 | membrane glycoprotein | M | ORF5; structural protein |
![]() |
61 | 0 | ORF6 protein | ORF6 | |
![]() |
121 | 4 | ORF7a protein | ORF7a | |
![]() |
43 | 0 | ORF7b | ORF7b | |
![]() |
121 | 9 | ORF8 protein | ORF8 | |
![]() |
419 | 240 | nucleocapsid phosphoprotein | N | ORF9; structural protein |
![]() |
38 | 0 | ORF10 protein | ORF10 |
KEGG_ID | structure | NAME | Number of identical compounds |
Number of similar compounds (tanimoto=0.5) |
OTHER NAME | EFFICACY |
![]() |
D01703 Ciclesonide (JAN/USAN/INN); Alvesco (TN); Omnaris (TN); Zetonna (TN) | 0 | 9 | Alvesco (TN); Omnaris (TN); Zetonna (TN) | Antiasthmatic, Anti-inflammatory, Glucocorticoid receptor agonist | |
![]() |
D01425 Lopinavir (JAN/USP/INN) | 1 | 39 | Antiviral, HIV protease inhibitor | ||
![]() |
D00427 Ritonavir (JAN/USP/INN); Norvir (TN) | 1 | 31 | Norvir (TN) | Antiviral, HIV protease inhibitor | |
![]() |
D09537 Favipiravir (JAN/USAN/INN); Avigan (TN) | 0 | 65 | Avigan (TN) | Antiviral, RNA replicase inhibitor | |
![]() |
D09537_1 Favipiravir-MTP; Active form of Favipiravir; | 1 | 150 | Active form of Favipiravir; | Antiviral, RNA replicase inhibitor | |
![]() |
D09537_2 Favipiravir-DTP; Active form of Favipiravir; | 0 | 141 | Active form of Favipiravir; | Antiviral, RNA replicase inhibitor | |
![]() |
D09537_3 Favipiravir-RTP; Active form of Favipiravir; | 1 | 150 | Active form of Favipiravir; | Antiviral, RNA replicase inhibitor | |
![]() |
D11472 Remdesivir (JAN/USAN); Veklury (TN) | 0 | 4 | Veklury (TN) | Antiviral, RNA polymerase inhibitor | |
![]() |
D11472_1 Remdesivir-monophosphate (USAN | 1 | 149 | Antiviral | ||
![]() |
D11472_2 Remdesivir-diphosphate (USAN | 0 | 133 | Antiviral | ||
![]() |
D11472_3 Remdesivir-triphosphate (USAN | 1 | 149 | Antiviral | ||
![]() |
D02366 Chloroquine (USP/INN) | 2 | 31 | Antimalarial, Amebicide | ||
![]() |
D08050 Hydroxychloroquine (INN); Polirreumin (TN) | 0 | 23 | Polirreumin (TN) | Antimalarial | |
![]() |
D01670 Nafamostat mesylate (USAN); Nafamostat mesilate (JP18); Ronastat (TN) | 1 | 31 | Nafamostat mesilate (JP18); Ronastat (TN) | Anticoagulant, Antifibrinolytic, Serine protease inhibitor | |
![]() |
D00429 Saquinavir (JAN/USP/INN); Fortovase (TN) | 1 | 10 | Fortovase (TN) | Antiviral, HIV protease inhibitor | |
![]() |
D01035 Cepharanthine (JAN); Cepharanthine (TN) | 0 | 0 | Cepharanthine (TN) | Antiallergic, Blood circulation promotor | |
![]() |
D00804 Ivermectin (JAN/USP/INN); Sklice (TN); Soolantra (TN); Stromectol (TN) | 0 | 1 | Sklice (TN); Soolantra (TN); Stromectol (TN) | Antiparasitic | |
![]() |
D00292 Dexamethasone (JP18/USP/INN); Decadron (TN); Maxidex (TN) | 1 | 110 | Decadron (TN); Maxidex (TN) | Anti-inflammatory, Antipruritic, Glucocorticoid receptor agonist | |
![]() |
D07486 Azithromycin (INN); Azasite (TN); Azithromycin (TN) | 1 | 25 | Azasite (TN); Azithromycin (TN) | Antibacterial, Protein biosynthesis inhibitor | |
![]() |
D08897 Dapagliflozin (USAN/INN); Forxiga (TN) | 0 | 35 | Forxiga (TN) | Antidiabetic, SGLT-2 inhibitor | |
![]() |
D00570 Colchicine (JP18/USP); Colchicine (TN) | 1 | 10 | Colchicine (TN) | Gout suppressant, Leukocyte (neutrophil) migration inhibitor, Tubulin polymerization inhibitor | |
![]() |
D07606 Camostat (INN) | 0 | 13 | Anti-inflammatory, Serine protease inhibitor | ||
![]() |
D10308 Baricitinib (JAN/USAN/INN); Olumiant (TN) | 1 | 9 | Olumiant (TN) | Anti-inflammatory, Antirheumatic, Immunosuppressant, Janus kinase (JAK) inhibitor | |
![]() |
D11943 Molnupiravir (JAN/USAN); Lagevrio (TN) | 0 | 112 | Lagevrio (TN) | Antiviral | |
![]() |
D12244 Nirmatrelvir (JAN/USAN); PF-07321332 | 3 | 47 | PF-07321332 | Antiviral | |
![]() |
D03506 Cinanserin hydrochloride (USAN) | 0 | 29 | Antiviral |
HOMCOS is developed and maintained by Protein Data Bank Japan, IPR, Osaka University. It is now supported by the project "Platform for Drug Discovery, Informatics, and Structural Life Science" by MEXT, Japan.
References