#WARNING:Can't open blastfile '/filesv4_homcos_data/TMPOUTSCH/19598.bltA' #WARNING:Can't open blastfile '/filesv4_homcos_data/TMPOUTSCH/19598.psiA'

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PID QueryLength Homolgous Sequence in PDB UniProt Query TITLE
19598 4382 0 P0C6U8(R1A_SARS) RecName: Full=Replicase polyprotein 1a; Short=pp1a;AltName: Full=ORF1a polyprotein;Contains: RecName: Full=Non-structural protein 1; Short=nsp1; AltName: Full=Leader protein;Contains: RecName: Full=Non-structural protein 2; Short=nsp2; AltName: Full=p65 homolog;Contains: RecName: Full=Non-structural protein 3; Short=nsp3; EC=3.4.19.12; EC=3.4.22.-; AltName: Full=PL2-PRO; AltName: Full=Papain-like proteinase; Short=PL-PRO;Contains: RecName: Full=Non-structural protein 4; Short=nsp4;Contains: RecName: Full=3C-like proteinase; Short=3CL-PRO; Short=3CLp; EC=3.4.22.69; AltName: Full=Main protease; Short=Mpro; AltName: Full=Non-structural protein 5; Short=nsp5; AltName: Full=SARS coronavirus main proteinase;Contains: RecName: Full=Non-structural protein 6; Short=nsp6;Contains: RecName: Full=Non-structural protein 7; Short=nsp7;Contains: RecName: Full=Non-structural protein 8; Short=nsp8;Contains: RecName: Full=Non-structural protein 9; Short=nsp9;Contains: RecName: Full=Non-structural protein 10; Short=nsp10; AltName: Full=Growth factor-like peptide; Short=GFL;Contains: RecName: Full=Non-structural protein 11; Short=nsp11;
QUERYSEQ 
MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGVLPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRNVLLRKNGNKGAGGHSYGIDLKSYDLGDELG
TDPIEDYEQNWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI
RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYLPTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRASADIGSGHTGITGDNVETLNEDL
LEILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY
VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQCIRGKEQLQLLMPLKAPKEVTFLEGDSHDTV
LTSEEVVLKNGELEALETPVDSFTNGAIVGTPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE
WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVA
GALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQK
PVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEEILGTVSWN
LREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTELG
VEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNN
CYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLC
ANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYR
HYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIA
THGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNS
SNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVEC
TTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLD
QALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSE
QLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTV
LRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDA
MNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFS
TFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR
KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYA
AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAA
CAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITG
NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG
AVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV
VPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGP
KVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVC
GMWKGYGCSCDQLREPLMQSADASTFLNGFAV
[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]

UniProt Feature Tables [P0C6U8(R1A_SARS)]

4382
region name description
1-4382 CHAIN /note="Replicase polyprotein 1a" /id="PRO_0000338254"
1-180 CHAIN /note="Non-structural protein 1" /id="PRO_0000338255"
181-818 CHAIN /note="Non-structural protein 2" /id="PRO_0000338256"
819-2740 CHAIN /note="Non-structural protein 3" /id="PRO_0000338257"
2741-3240 CHAIN /note="Non-structural protein 4" /id="PRO_0000338258"
3241-3546 CHAIN /note="3C-like proteinase" /id="PRO_0000338259"
3547-3836 CHAIN /note="Non-structural protein 6" /id="PRO_0000338260"
3837-3919 CHAIN /note="Non-structural protein 7" /id="PRO_0000338261"
3920-4117 CHAIN /note="Non-structural protein 8" /id="PRO_0000338262"
4118-4230 CHAIN /note="Non-structural protein 9" /id="PRO_0000338263"
4231-4369 CHAIN /note="Non-structural protein 10" /id="PRO_0000338264"
4370-4382 CHAIN /note="Non-structural protein 11" /id="PRO_0000338265"
1-2202 TOPO_DOM /note="Cytoplasmic"
2203-2223 TRANSMEM /note="Helical"
2224-2303 TOPO_DOM /note="Lumenal"
2304-2324 TRANSMEM /note="Helical"
2325-2350 TOPO_DOM /note="Cytoplasmic"
2351-2371 TRANSMEM /note="Helical"
2372-2754 TOPO_DOM /note="Lumenal"
2755-2775 TRANSMEM /note="Helical"
2776-2991 TOPO_DOM /note="Cytoplasmic"
2992-3012 TRANSMEM /note="Helical"
3013-3021 TOPO_DOM /note="Lumenal"
3022-3042 TRANSMEM /note="Helical"
3043-3053 TOPO_DOM /note="Cytoplasmic"
3054-3074 TRANSMEM /note="Helical"
3075-3076 TOPO_DOM /note="Lumenal"
3077-3097 TRANSMEM /note="Helical"
3098-3104 TOPO_DOM /note="Cytoplasmic"
3105-3125 TRANSMEM /note="Helical"
3126-3141 TOPO_DOM /note="Lumenal"
3142-3162 TRANSMEM /note="Helical"
3163-3563 TOPO_DOM /note="Cytoplasmic"
3564-3584 TRANSMEM /note="Helical"
3585-3585 TOPO_DOM /note="Lumenal"
3586-3606 TRANSMEM /note="Helical"
3607-3611 TOPO_DOM /note="Cytoplasmic"
3612-3632 TRANSMEM /note="Helical"
3633-3657 TOPO_DOM /note="Lumenal"
3658-3678 TRANSMEM /note="Helical"
3679-3684 TOPO_DOM /note="Cytoplasmic"
3685-3704 TRANSMEM /note="Helical"
3705-3727 TOPO_DOM /note="Lumenal"
3728-3748 TRANSMEM /note="Helical"
3749-3755 TOPO_DOM /note="Cytoplasmic"
3756-3776 TRANSMEM /note="Helical"
3777-4382 TOPO_DOM /note="Lumenal"
821-930 DOMAIN /note="Ubiquitin-like 1"
1003-1169 DOMAIN /note="Macro 1"
1207-1335 DOMAIN /note="Macro 2"
1343-1470 DOMAIN /note="Macro 3"
1472-1538 DOMAIN /note="DPUP"
1542-1597 DOMAIN /note="Ubiquitin-like 2"
1611-1875 DOMAIN /note="Peptidase C16"
1888-1998 DOMAIN /note="Nucleic acid-binding"
3142-3240 DOMAIN /note="Nsp4C"
3241-3546 DOMAIN /note="Peptidase C30"
3837-3919 DOMAIN /note="RdRp Nsp7 cofactor"
3920-4117 DOMAIN /note="RdRp Nsp8 cofactor"
4118-4230 DOMAIN /note="Nsp9 ssRNA-binding"
4231-4369 DOMAIN /note="ExoN/MTase coactivator"
1729-1766 ZN_FING /note="C4-type"
4304-4320 ZN_FING
4347-4360 ZN_FING
2092-2371 REGION /note="HD1"
2755-3162 REGION /note="HD2"
3564-3776 REGION /note="HD3"
930-1001 COMPBIAS /note="Glu-rich"
2210-2213 COMPBIAS /note="Poly-Leu"
3766-3769 COMPBIAS /note="Poly-Cys"
1651-1651 ACT_SITE /note="For PL-PRO activity"
1812-1812 ACT_SITE /note="For PL-PRO activity"
3281-3281 ACT_SITE /note="For 3CL-PRO activity"
3385-3385 ACT_SITE /note="For 3CL-PRO activity"
4304-4304 METAL /note="Zinc"
4304-4304 METAL /note="Zinc 1"
4307-4307 METAL /note="Zinc"
4307-4307 METAL /note="Zinc 1"
4313-4313 METAL /note="Zinc"
4313-4313 METAL /note="Zinc 1"
4320-4320 METAL /note="Zinc"
4320-4320 METAL /note="Zinc 1"
4347-4347 METAL /note="Zinc"
4347-4347 METAL /note="Zinc 2"
4350-4350 METAL /note="Zinc"
4350-4350 METAL /note="Zinc 2"
4358-4358 METAL /note="Zinc"
4358-4358 METAL /note="Zinc 2"
4360-4360 METAL /note="Zinc 2"

No homologue is found in PDB.

Please check [SiteTable] for homologues.