Contact Molecules for Homologous Proteins


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PID QueryLength Homolgous Sequence in PDB UniProt Query TITLE
31126 468 107 P08887(IL6RA_HUMAN) RecName: Full=Interleukin-6 receptor subunit alpha ; Short=IL-6 receptor subunit alpha; Short=IL-6R subunit alpha; Short=IL-6R-alpha; Short=IL-6RA;AltName: Full=IL-6R 1;AltName: Full=Membrane glycoprotein 80; Short=gp80;AltName: CD_antigen=CD126;Contains: RecName: Full=Soluble interleukin-6 receptor subunit alpha ; Short=sIL6R ;Flags: Precursor;
QUERYSEQ
MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLV
RKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ
GEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPVQDSSSVPLPTFLVAGGSLAFGTLLCIAIVLRFKKTWKLRALKEGKTSMHPPYSLGQLVPERPRPTPVLVPLISPPVSPSSLGSDNTSSHNRPDA
RDPRSPYDISNTDYFFPR
[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]

UniProt Feature Tables [P08887(IL6RA_HUMAN)]

468
region name description
1-19 SIGNAL
20-468 CHAIN /note="Interleukin-6 receptor subunit alpha" /id="PRO_0000010895"
20-355 CHAIN /note="Soluble interleukin-6 receptor subunit alpha" /id="PRO_0000450730"
20-365 TOPO_DOM /note="Extracellular"
366-386 TRANSMEM /note="Helical"
387-468 TOPO_DOM /note="Cytoplasmic"
26-112 DOMAIN /note="Ig-like C2-type"
113-217 DOMAIN /note="Fibronectin type-III 1"
218-316 DOMAIN /note="Fibronectin type-III 2"
303-328 REGION /note="Disordered"
421-468 REGION /note="Disordered"
311-328 COMPBIAS /note="Polar residues"
1-468 DISORDER predicted by DISOPRED

MONOMER
468
pdb_id a1 identity[%]2 description
1n26 A 100.0 IL6A_HUMAN IL-6 Receptor alpha chain
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue.
HETERO
468 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
8d82[2] C IL6RB_HUMAN Interleukin-6 receptor subunit beta[589 aa] A 100.0
/100.0
11
/11
IL6RA_HUMAN Soluble interleukin-6 receptor subunit alpha
8d82[2] F IL6RB_HUMAN Interleukin-6 receptor subunit beta[589 aa] A 100.0
/100.0
6
/6
IL6RA_HUMAN Soluble interleukin-6 receptor subunit alpha
8qy4[6] B IL6RB_MOUSE Interleukin-6 receptor subunit beta[583 aa] E 41.7
/31.7
12
/12
I11RA_HUMAN Interleukin-11 receptor subunit alpha
8qy4[6] D IL6RB_MOUSE Interleukin-6 receptor subunit beta[583 aa] E 0.0
/31.7
6
/6
I11RA_HUMAN Interleukin-11 receptor subunit alpha
7dc8[2] A Switch Ab Fab light chain[212 aa] C 100.0
/99.5
5
/5
IL6RA_HUMAN Interleukin-6 receptor subunit alpha
7dc8[2] B Switch Ab Fab heavy chain[209 aa] C 100.0
/99.5
9
/9
IL6RA_HUMAN Interleukin-6 receptor subunit alpha
5fuc[1] E VHH6[110 aa] C 100.0
/99.0
10
/10
D6R9R8_HUMAN IL6RA_HUMAN INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, INTERLEUKIN-..
5fuc[1] A IL6_HUMAN INTERLEUKIN-6[152 aa] D 100.0
/99.0
12
/12
D6R9R8_HUMAN IL6RA_HUMAN INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, INTERLEUKIN-..
5fuc[1] F VHH6[124 aa] D 100.0
/99.0
10
/10
D6R9R8_HUMAN IL6RA_HUMAN INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, INTERLEUKIN-..
1p9m[2] A IL6RB_HUMAN Interleukin-6 receptor beta chain[298 aa] C 100.0
/100.0
12
/12
IL6RA_HUMAN Interleukin-6 receptor alpha chain
1p9m[2] A IL6RB_HUMAN Interleukin-6 receptor beta chain[298 aa] C 100.0
/100.0
8
/8
IL6RA_HUMAN Interleukin-6 receptor alpha chain
7u7n[1] B IL6RB_HUMAN Interleukin-6 receptor subunit beta[298 aa] C 33.3
/26.7
3
/3
IL27B_HUMAN Interleukin-27 subunit beta
8d85[1] D IL6RB_HUMAN Interleukin-6 receptor subunit beta[296 aa] A 0.0
/26.7
2
/3
IL27B_HUMAN Interleukin-27 subunit beta
8dps[8] A IL6RB_HUMAN Interleukin-6 receptor subunit beta[297 aa] C 36.4
/33.9
11
/11
I11RA_HUMAN Interleukin-11 receptor subunit alpha
8dps[8] D IL6RB_HUMAN Interleukin-6 receptor subunit beta[297 aa] C 0.0
/33.9
4
/4
I11RA_HUMAN Interleukin-11 receptor subunit alpha
8d74[1] B CNTF_HUMAN Ciliary neurotrophic factor[174 aa] A 33.3
/29.9
12
/12
IL6RB_HUMAN Interleukin-6 receptor subunit beta
8d74[1] B CNTF_HUMAN Ciliary neurotrophic factor[174 aa] C 14.3
/34.7
14
/14
CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha..
8d74[2] A IL6RB_HUMAN Interleukin-6 receptor subunit beta[392 aa] C 36.4
/34.7
11
/11
CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha..
8dpt[2] A IL6RB_HUMAN Interleukin-6 receptor subunit beta[398 aa] C 33.3
/34.2
15
/15
I11RA_HUMAN Interleukin-11 receptor subunit alpha
8dpt[2] D IL6RB_HUMAN Interleukin-6 receptor subunit beta[398 aa] C 0.0
/34.2
3
/3
I11RA_HUMAN Interleukin-11 receptor subunit alpha
8d7e[1] B H4H25311P2 antibody Fab fragment light chain[215 a.. A 33.3
/33.9
9
/9
CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha..
8d7e[1] C H4H25311P2 antibody Fab fragment heavy chain[217 a.. A 27.3
/33.9
11
/11
CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha..
8d7e[1] E REGN8938 antibody Fab fragment heavy chain[214 aa].. A 0.0
/33.9
3
/11
CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha..
8dps[10] B IL11_HUMAN Interleukin-11[165 aa] A 40.0
/28.5
10
/10
IL6RB_HUMAN Interleukin-6 receptor subunit beta
8dps[12] B IL11_HUMAN Interleukin-11[165 aa] C 6.7
/33.9
15
/18
I11RA_HUMAN Interleukin-11 receptor subunit alpha
8dpt[2] E IL11_HUMAN Interleukin-11[165 aa] A 0.0
/28.6
1
/10
IL6RB_HUMAN Interleukin-6 receptor subunit beta
8qy4[2] A IL11_HUMAN Interleukin-11[165 aa] E 0.0
/31.7
10
/15
I11RA_HUMAN Interleukin-11 receptor subunit alpha
1f45[1] B I12A_HUMAN INTERLEUKIN-12 ALPHA CHAIN[133 aa] A 25.0
/30.4
20
/21
I12B_HUMAN INTERLEUKIN-12 BETA CHAIN
1pvh[2] B LIF_HUMAN Leukemia inhibitory factor[169 aa] A 23.1
/29.9
13
/13
IL6RB_HUMAN Interleukin-6 receptor beta chain
8d6a[1] A LIF_HUMAN Leukemia inhibitory factor[169 aa] B 30.0
/29.9
10
/10
IL6RB_HUMAN Interleukin-6 receptor subunit beta
8d74[2] C CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha.. A 18.2
/29.9
11
/11
IL6RB_HUMAN Interleukin-6 receptor subunit beta
8d7h[3] B CLCF1_HUMAN Cardiotrophin-like cytokine factor 1[178 aa] A 12.5
/33.9
16
/17
CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha..
8d7h[3] B CLCF1_HUMAN Cardiotrophin-like cytokine factor 1[178 aa] C 9.1
/29.6
11
/13
CRLF1_HUMAN Cytokine receptor-like factor 1
8d7h[2] E CLCF1_HUMAN Cardiotrophin-like cytokine factor 1[178 aa] C 20.0
/29.6
5
/11
CRLF1_HUMAN Cytokine receptor-like factor 1
3d85[4] C IL23A_HUMAN Interleukin-23 subunit p19[133 aa] D 12.5
/28.3
16
/17
IL12B_HUMAN Interleukin-12 subunit p40
4grw[8] A IL23A_HUMAN Interleukin-23 subunit alpha[130 aa] B 18.8
/29.2
16
/17
IL12B_HUMAN Interleukin-12 subunit beta
8cr8[1] B IL23A_HUMAN Interleukin-23 subunit alpha[138 aa] A 14.3
/29.8
14
/15
IL12B_HUMAN Interleukin-12 subunit beta
3d87[6] A IL23A_HUMAN Interleukin-23 subunit p19[161 aa] B 16.7
/28.8
18
/19
IL12B_HUMAN Interleukin-12 subunit p40
3d87[1] C IL23A_HUMAN Interleukin-23 subunit p19[159 aa] B 0.0
/28.8
2
/2
IL12B_HUMAN Interleukin-12 subunit p40
5mzv[1] B IL23A_HUMAN Interleukin-23 subunit alpha[137 aa] A 18.8
/28.0
16
/17
IL12B_HUMAN Interleukin-12 subunit beta
5mzv[1] C IL23R_HUMAN Interleukin-23 receptor[293 aa] A 0.0
/28.0
2
/6
IL12B_HUMAN Interleukin-12 subunit beta
6wdq[1] C IL23R_HUMAN Interleukin-23 receptor[293 aa] A 66.7
/28.3
3
/5
IL12B_HUMAN Interleukin-12 subunit beta
8oe4[1] C IL23R_HUMAN CALM1_HUMAN Interleukin-23 receptor,Calmodulin-1[293 aa] A 0.0
/29.3
1
/1
IL12B_HUMAN Interleukin-12 subunit beta
8oe4[1] D I12R1_HUMAN DAPK1_HUMAN Interleukin-12 receptor subunit beta-1,Death-assoc.. A 0.0
/29.3
8
/16
IL12B_HUMAN Interleukin-12 subunit beta
3hmx[1] B IL12A_HUMAN Interleukin-12 subunit alpha[176 aa] A 17.6
/29.0
17
/18
IL12B_HUMAN Interleukin-12 subunit beta
3hmx[1] D USTEKINUMAB FAB HEAVY CHAIN[217 aa] A 25.0
/29.0
12
/13
IL12B_HUMAN Interleukin-12 subunit beta
3qwr[1] C ADNECTIN[91 aa] A 28.6
/28.9
21
/22
IL12B_HUMAN Interleukin-12 subunit beta
8d82[2] A IL6RA_HUMAN Soluble interleukin-6 receptor subunit alpha[296 a.. C 9.1
/28.6
11
/11
IL6RB_HUMAN Interleukin-6 receptor subunit beta
6uib[1] C Peptide 23-652[15 aa] B 25.0
/28.6
12
/12
IL12B_HUMAN Interleukin-12 subunit beta
5njd[1] J IL23A_HUMAN Interleukin-23 subunit alpha[141 aa] I 18.8
/28.6
16
/16
IL12B_HUMAN Interleukin-12 subunit beta
3duh[1] D IL23A_HUMAN Interleukin-23 subunit alpha[137 aa] B 12.5
/28.5
16
/17
IL12B_HUMAN Interleukin-12 subunit beta
4grw[2] G Nanobody 124C4[125 aa] B 23.1
/29.2
13
/15
IL12B_HUMAN Interleukin-12 subunit beta
4grw[2] J Nanobody 37D5[122 aa] B 75.0
/29.2
4
/4
IL12B_HUMAN Interleukin-12 subunit beta
8dpt[8] C I11RA_HUMAN Interleukin-11 receptor subunit alpha[294 aa] A 9.1
/28.6
11
/12
IL6RB_HUMAN Interleukin-6 receptor subunit beta
5njd[6] U Briakinumab FAb Light chain[215 aa] A 0.0
/27.9
3
/8
IL12B_HUMAN Interleukin-12 subunit beta
5njd[6] V Briakinumab FAb Heavy chain[205 aa] A 0.0
/27.9
2
/10
IL12B_HUMAN Interleukin-12 subunit beta
6wdq[1] D I12R1_HUMAN Interleukin-12 receptor subunit beta-1[109 aa] A 0.0
/28.3
8
/14
IL12B_HUMAN Interleukin-12 subunit beta
1i1r[2] B Q98823_HHV8 VIRAL IL-6[167 aa] A 36.4
/28.2
11
/11
IL6RB_HUMAN INTERLEUKIN-6 RECEPTOR BETA CHAIN
4grw[3] H Nanobody 22E11[123 aa] B 0.0
/29.2
10
/17
IL12B_HUMAN Interleukin-12 subunit beta
7u7n[1] D IL27A_HUMAN Interleukin-27 subunit alpha[191 aa] B 0.0
/28.9
1
/12
IL6RB_HUMAN Interleukin-6 receptor subunit beta
7u7n[2] D IL27A_HUMAN Interleukin-27 subunit alpha[191 aa] C 0.0
/26.7
20
/21
IL27B_HUMAN Interleukin-27 subunit beta
7u7n[2] A I27RA_HUMAN Interleukin-27 receptor subunit alpha[195 aa] C 40.0
/26.7
10
/10
IL27B_HUMAN Interleukin-27 subunit beta
7z0l[1] B IL27B_MOUSE IL27A_MOUSE Interleukin-27 subunit beta,Interleukin-27 subunit.. A 0.0
/26.3
1
/14
IL6RB_MOUSE Interleukin-6 receptor subunit beta
1p9m[4] B IL6_HUMAN Interleukin-6[163 aa] A 33.3
/28.9
12
/12
IL6RB_HUMAN Interleukin-6 receptor beta chain
1p9m[2] B IL6_HUMAN Interleukin-6[163 aa] C 100.0
/100.0
15
/15
IL6RA_HUMAN Interleukin-6 receptor alpha chain
5fuc[1] B IL6_HUMAN INTERLEUKIN-6[160 aa] C 100.0
/99.0
18
/18
D6R9R8_HUMAN IL6RA_HUMAN INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, INTERLEUKIN-..
8d82[2] B IL6_HUMAN Interleukin-6[169 aa] A 100.0
/100.0
12
/12
IL6RA_HUMAN Soluble interleukin-6 receptor subunit alpha
8qy5[4] B IL6_HUMAN Interleukin-6[157 aa] A 11.1
/26.1
9
/10
IL6RB_MOUSE Interleukin-6 receptor subunit beta
8qy5[4] B IL6_HUMAN Interleukin-6[157 aa] C 100.0
/100.0
11
/11
IL6RA_HUMAN Interleukin-6 receptor subunit alpha
1p9m[2] C IL6RA_HUMAN Interleukin-6 receptor alpha chain[201 aa] A 10.0
/28.9
10
/11
IL6RB_HUMAN Interleukin-6 receptor beta chain
8qy5[4] C IL6RA_HUMAN Interleukin-6 receptor subunit alpha[201 aa] A 9.1
/26.1
11
/11
IL6RB_MOUSE Interleukin-6 receptor subunit beta
8dps[2] C I11RA_HUMAN Interleukin-11 receptor subunit alpha[200 aa] A 10.0
/28.5
10
/11
IL6RB_HUMAN Interleukin-6 receptor subunit beta
8qy4[2] E I11RA_HUMAN Interleukin-11 receptor subunit alpha[197 aa] B 9.1
/26.1
11
/11
IL6RB_MOUSE Interleukin-6 receptor subunit beta
3mzg[9] A PRL_HUMAN Prolactin[186 aa] B 0.0
/24.7
21
/22
PRLR_HUMAN Prolactin receptor
3ew3[1] A PRL_HUMAN Prolactin[185 aa] B 0.0
/25.4
20
/21
PRLR_RAT Prolactin receptor
1f6f[1] A CSH_SHEEP PLACENTAL LACTOGEN[183 aa] B 4.5
/25.3
22
/23
PRLR_RAT PROLACTIN RECEPTOR
3d48[1] A PRL_HUMAN Prolactin[165 aa] B 0.0
/25.1
21
/22
PRLR_HUMAN Prolactin receptor
3hmx[1] C USTEKINUMAB FAB LIGHT CHAIN[214 aa] A 14.3
/29.0
7
/9
IL12B_HUMAN Interleukin-12 subunit beta
4i18[1] C antibody light chain[215 aa] E 60.0
/24.9
5
/5
PRLR_HUMAN Prolactin receptor
4i18[1] D antibody heavy chain[220 aa] E 20.0
/24.9
20
/21
PRLR_HUMAN Prolactin receptor
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
COMPOUND
468 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1n26[2] H CYS
CYSTEINE[7 atoms]
A 100.0
/100.0
5
/5
IL6A_HUMAN IL-6 Receptor alpha chain
7dc8[2] H ATP
ADENOSINE-5'-TRIPHOSPHATE[31 atoms]
C 100.0
/99.5
1
/1
IL6RA_HUMAN Interleukin-6 receptor subunit alpha
1f42[1] C MNB
5-MERCAPTO-2-NITRO-BENZOIC ACID[13 atoms]
A 66.7
/28.9
3
/3
I12B_HUMAN INTERLEUKIN-12 BETA CHAIN
1f42[1] D MNB
5-MERCAPTO-2-NITRO-BENZOIC ACID[13 atoms]
A 50.0
/28.9
6
/6
I12B_HUMAN INTERLEUKIN-12 BETA CHAIN
3d87[1] G MAN
alpha-D-mannopyranose[11 atoms]
D 0.0
/28.9
4
/4
IL12B_HUMAN Interleukin-12 subunit p40
1n26[4] D NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..
A 100.0
/100.0
5
/5
IL6A_HUMAN IL-6 Receptor alpha chain
1n26[27] E NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..
A 100.0
/100.0
3
/3
IL6A_HUMAN IL-6 Receptor alpha chain
1n26[1] E NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..
A 100.0
/100.0
3
/3
IL6A_HUMAN IL-6 Receptor alpha chain
3duh[3] E NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..
A 0.0
/28.6
2
/7
IL12B_HUMAN Interleukin-12 subunit beta
5fuc[3] G NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..
C 100.0
/99.0
3
/3
D6R9R8_HUMAN IL6RA_HUMAN INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, INTERLEUKIN-..
6o4p[7] E NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..
A 50.0
/35.0
4
/4
I11RA_HUMAN Interleukin-11 receptor subunit alpha
7u7n[2] K NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..
B 0.0
/28.9
1
/2
IL6RB_HUMAN Interleukin-6 receptor subunit beta
7z0l[1] J NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..
A 50.0
/26.3
2
/2
IL6RB_MOUSE Interleukin-6 receptor subunit beta
8d74[2] P NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..
C 0.0
/34.7
1
/1
CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha..
8d7h[2] V NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..
C 0.0
/29.6
1
/1
CRLF1_HUMAN Cytokine receptor-like factor 1
8d82[2] S NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..
A 100.0
/100.0
3
/3
IL6RA_HUMAN Soluble interleukin-6 receptor subunit alpha
8d82[3] T NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..
C 100.0
/28.6
1
/1
IL6RB_HUMAN Interleukin-6 receptor subunit beta
8d85[1] H NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..
A 16.7
/26.7
6
/6
IL27B_HUMAN Interleukin-27 subunit beta
8qy4[2] P NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..
B 0.0
/26.1
3
/3
IL6RB_MOUSE Interleukin-6 receptor subunit beta
8qy4[6] Q NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..
B 33.3
/26.1
3
/3
IL6RB_MOUSE Interleukin-6 receptor subunit beta
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
METAL
468 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1pvh[1] E IOD
IODIDE ION[1 atoms]
A 100.0
/29.9
1
/1
IL6RB_HUMAN Interleukin-6 receptor beta chain
8cr8[1] D TB
TERBIUM(III) ION[1 atoms]
A 0.0
/29.8
1
/2
IL12B_HUMAN Interleukin-12 subunit beta
3d87[2] F K
POTASSIUM ION[1 atoms]
B 50.0
/28.8
2
/2
IL12B_HUMAN Interleukin-12 subunit p40
3mzg[7] C NA
SODIUM ION[1 atoms]
B 0.0
/24.7
2
/2
PRLR_HUMAN Prolactin receptor
3mzg[7] E NA
SODIUM ION[1 atoms]
B 40.0
/24.7
5
/5
PRLR_HUMAN Prolactin receptor
3mzg[7] F NA
SODIUM ION[1 atoms]
B 0.0
/24.7
5
/5
PRLR_HUMAN Prolactin receptor
3nce[1] C NA
SODIUM ION[1 atoms]
B 0.0
/24.7
2
/3
PRLR_HUMAN Prolactin receptor
5mj3[1] H NA
SODIUM ION[1 atoms]
A 33.3
/28.3
3
/3
IL12B_HUMAN Interleukin-12 subunit beta
5mj3[1] I NA
SODIUM ION[1 atoms]
A 0.0
/28.3
3
/3
IL12B_HUMAN Interleukin-12 subunit beta
5mzv[1] K NA
SODIUM ION[1 atoms]
A 100.0
/28.0
1
/1
IL12B_HUMAN Interleukin-12 subunit beta
3mzg[7] D CL
CHLORIDE ION[1 atoms]
B 50.0
/24.7
2
/2
PRLR_HUMAN Prolactin receptor
5mzv[1] J CL
CHLORIDE ION[1 atoms]
A 0.0
/28.0
2
/3
IL12B_HUMAN Interleukin-12 subunit beta
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
OTHERPOLY
468 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1n26[2] B 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-al.. A 100.0
/100.0
9
/9
IL6A_HUMAN IL-6 Receptor alpha chain
6wdq[1] E beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. A 0.0
/28.3
1
/2
IL12B_HUMAN Interleukin-12 subunit beta
7u7n[1] H beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. C 16.7
/26.7
6
/6
IL27B_HUMAN Interleukin-27 subunit beta
8dps[4] H beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. C 0.0
/33.9
3
/3
I11RA_HUMAN Interleukin-11 receptor subunit alpha
8dpu[6] T beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. C 16.7
/35.3
6
/6
I11RA_HUMAN Interleukin-11 receptor subunit alpha
1f42[2] B alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-be.. A 0.0
/28.9
3
/7
I12B_HUMAN INTERLEUKIN-12 BETA CHAIN
8cr8[1] C alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. A 25.0
/29.8
4
/9
IL12B_HUMAN Interleukin-12 subunit beta
3qwr[2] D alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. A 0.0
/28.9
3
/7
IL12B_HUMAN Interleukin-12 subunit beta
5mxa[1] C alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. B 0.0
/28.0
2
/8
IL12B_HUMAN Interleukin-12 subunit beta
6o4p[1] C alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. A 0.0
/35.0
5
/5
I11RA_HUMAN Interleukin-11 receptor subunit alpha
3l5h[1] C beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1.. A 0.0
/28.8
1
/1
IL6RB_HUMAN Interleukin-6 receptor subunit beta
3hmx[3] E alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose.. A 0.0
/29.0
3
/7
IL12B_HUMAN Interleukin-12 subunit beta
4grw[8] K alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose.. B 0.0
/29.2
3
/9
IL12B_HUMAN Interleukin-12 subunit beta
5mzv[1] E alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. A 25.0
/28.0
4
/10
IL12B_HUMAN Interleukin-12 subunit beta
1n26[2] C 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. A 100.0
/100.0
5
/5
IL6A_HUMAN IL-6 Receptor alpha chain
3l5h[4] B 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. A 50.0
/28.8
2
/2
IL6RB_HUMAN Interleukin-6 receptor subunit beta
6o4p[1] D 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. B 0.0
/35.4
4
/4
I11RA_HUMAN Interleukin-11 receptor subunit alpha
6uib[1] D 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. B 0.0
/28.6
4
/7
IL12B_HUMAN Interleukin-12 subunit beta
7z0l[4] F 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. A 20.0
/26.3
5
/5
IL6RB_MOUSE Interleukin-6 receptor subunit beta
8d74[5] F 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. C 40.0
/34.7
5
/5
CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha..
8d7e[3] H 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. A 50.0
/33.9
2
/4
CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha..
8d7h[2] M 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. C 0.0
/29.6
2
/2
CRLF1_HUMAN Cytokine receptor-like factor 1
8d82[2] G 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. A 100.0
/100.0
1
/1
IL6RA_HUMAN Soluble interleukin-6 receptor subunit alpha
8qy4[2] I 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. E 40.0
/31.7
5
/5
I11RA_HUMAN Interleukin-11 receptor subunit alpha
8qy4[2] J 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. E 0.0
/31.7
5
/5
I11RA_HUMAN Interleukin-11 receptor subunit alpha
8qy5[4] J 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. A 0.0
/26.1
4
/4
IL6RB_MOUSE Interleukin-6 receptor subunit beta
8qy5[4] K 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. A 0.0
/26.1
5
/5
IL6RB_MOUSE Interleukin-6 receptor subunit beta
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
HOMO
468 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1n26[1] A IL6A_HUMAN IL-6 Receptor alpha chain[299 aa] A 100.0
/100.0
11
/11
IL6A_HUMAN IL-6 Receptor alpha chain
1n26[1] A IL6A_HUMAN IL-6 Receptor alpha chain[299 aa] A 100.0
/100.0
15
/15
IL6A_HUMAN IL-6 Receptor alpha chain
1bqu[1] B IL6RB_HUMAN PROTEIN (GP130)[215 aa] A 33.3
/30.2
9
/9
IL6RB_HUMAN PROTEIN (GP130)
1bqu[1] A IL6RB_HUMAN PROTEIN (GP130)[208 aa] B 20.0
/29.9
10
/11
IL6RB_HUMAN PROTEIN (GP130)
8d7h[2] F CRLF1_HUMAN Cytokine receptor-like factor 1[303 aa] C 40.0
/29.6
5
/6
CRLF1_HUMAN Cytokine receptor-like factor 1
3npz[2] C PRLR_RAT Prolactin receptor[199 aa] B 15.4
/25.7
13
/14
PRLR_RAT Prolactin receptor
3ew3[1] C PRLR_RAT Prolactin receptor[181 aa] B 10.0
/25.4
10
/11
PRLR_RAT Prolactin receptor
1f6f[1] C PRLR_RAT PROLACTIN RECEPTOR[169 aa] B 10.0
/25.3
10
/11
PRLR_RAT PROLACTIN RECEPTOR
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
PRECIPITANT
468 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1bqu[3] C SO4
SULFATE ION[5 atoms]
A 0.0
/30.2
4
/4
IL6RB_HUMAN PROTEIN (GP130)
1bqu[9] E SO4
SULFATE ION[5 atoms]
A 100.0
/30.2
2
/2
IL6RB_HUMAN PROTEIN (GP130)
1bqu[1] I SO4
SULFATE ION[5 atoms]
B 0.0
/29.9
2
/2
IL6RB_HUMAN PROTEIN (GP130)
1bqu[3] J SO4
SULFATE ION[5 atoms]
B 0.0
/29.9
3
/3
IL6RB_HUMAN PROTEIN (GP130)
1n26[2] F SO4
SULFATE ION[5 atoms]
A 100.0
/100.0
3
/3
IL6A_HUMAN IL-6 Receptor alpha chain
1n26[2] G SO4
SULFATE ION[5 atoms]
A 100.0
/100.0
3
/3
IL6A_HUMAN IL-6 Receptor alpha chain
3l5h[1] I SO4
SULFATE ION[5 atoms]
A 0.0
/28.8
1
/1
IL6RB_HUMAN Interleukin-6 receptor subunit beta
3l5h[1] J SO4
SULFATE ION[5 atoms]
A 0.0
/28.8
1
/1
IL6RB_HUMAN Interleukin-6 receptor subunit beta
6o4p[1] I SO4
SULFATE ION[5 atoms]
A 0.0
/35.0
1
/3
I11RA_HUMAN Interleukin-11 receptor subunit alpha
6o4p[2] J SO4
SULFATE ION[5 atoms]
A 33.3
/35.0
3
/3
I11RA_HUMAN Interleukin-11 receptor subunit alpha
6o4p[1] L SO4
SULFATE ION[5 atoms]
B 0.0
/35.4
2
/2
I11RA_HUMAN Interleukin-11 receptor subunit alpha
6o4p[1] M SO4
SULFATE ION[5 atoms]
B 0.0
/35.4
3
/3
I11RA_HUMAN Interleukin-11 receptor subunit alpha
6o4p[1] P SO4
SULFATE ION[5 atoms]
B 0.0
/35.4
1
/1
I11RA_HUMAN Interleukin-11 receptor subunit alpha
3d87[2] E PO4
PHOSPHATE ION[5 atoms]
B 50.0
/28.8
2
/2
IL12B_HUMAN Interleukin-12 subunit p40
5mj3[1] G PGE
TRIETHYLENE GLYCOL[10 atoms]
A 75.0
/28.3
4
/4
IL12B_HUMAN Interleukin-12 subunit beta
1bqu[1] F GOL
GLYCEROL[6 atoms]
A 50.0
/30.2
6
/6
IL6RB_HUMAN PROTEIN (GP130)
1bqu[2] G GOL
GLYCEROL[6 atoms]
A 25.0
/30.2
8
/8
IL6RB_HUMAN PROTEIN (GP130)
1bqu[1] L GOL
GLYCEROL[6 atoms]
B 50.0
/29.9
6
/6
IL6RB_HUMAN PROTEIN (GP130)
1bqu[1] M GOL
GLYCEROL[6 atoms]
B 25.0
/29.9
4
/4
IL6RB_HUMAN PROTEIN (GP130)
4i18[1] K GOL
GLYCEROL[6 atoms]
E 83.3
/24.9
6
/6
PRLR_HUMAN Prolactin receptor
4i18[1] L ACT
ACETATE ION[4 atoms]
E 0.0
/24.9
2
/2
PRLR_HUMAN Prolactin receptor
3d48[1] D CO3
CARBONATE ION[4 atoms]
B 50.0
/25.1
2
/2
PRLR_HUMAN Prolactin receptor
3d48[1] E CO3
CARBONATE ION[4 atoms]
B 75.0
/25.1
4
/4
PRLR_HUMAN Prolactin receptor
3d48[1] F CO3
CARBONATE ION[4 atoms]
B 12.5
/25.1
8
/8
PRLR_HUMAN Prolactin receptor
3ncc[1] G CO3
CARBONATE ION[4 atoms]
B 0.0
/24.7
2
/2
PRLR_HUMAN Prolactin receptor
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.