Contact Molecules for Homologous Proteins | ||||
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PID | QueryLength | Homolgous Sequence in PDB | UniProt Query | TITLE |
4093875 | 540 | 46 | Q7Z434(MAVS_HUMAN) | RecName: Full=Mitochondrial antiviral-signaling protein ; Short=MAVS ;AltName: Full=CARD adapter inducing interferon beta ; Short=Cardif ;AltName: Full=Interferon beta promoter stimulator protein 1; Short=IPS-1;AltName: Full=Putative NF-kappa-B-activating protein 031N;AltName: Full=Virus-induced-signaling adapter; Short=VISA; |
QUERYSEQ |
MPFAEDKTYKYICRNFSNFCNVDVVEILPYLPCLTARDQDRLRATCTLSGNRDTLWHLFNTLQRRPGWVEYFIAALRGCELVDLADEVASVYQSYQPRTSDRPPDPLEPPSLPAERPGPPTPAAAHSIPYNSCREKEPSYPMPVQETQAP ESPGENSEQALQTLSPRAIPRNPDGGPLESSSDLAALSPLTSSGHQEQDTELGSTHTAGATSSLTPSRGPVSPSVSFQPLARSTPRASRLPGPTGSVVSTGTSFSSSSPGLASAGAAEGKQGAESDQAEPIICSSGAEAPANSLPSKVPT TLMPVNTVALKVPANPASVSTVPSKLPTSSKPPGAVPSNALTNPAPSKLPINSTRAGMVPSKVPTSMVLTKVSASTVPTDGSSRNEETPAAPTPAGATGGSSAWLDSSSENRGLGSELSKPGVLASQVDSPFSGCFEDLAISASTSLGMG PCHGPEENEYKSEGTFGIHVAENPSIQLLEGNPGPPADPDGGPRPQADRKFQEREVPCHRPSPGALWLQVAVTGVLVVTLLVVLYRRRLH |
540 | region | name | description |
1-540 | CHAIN | /note="Mitochondrial antiviral-signaling protein" /id="PRO_0000144096" | |
1-513 | TOPO_DOM | /note="Cytoplasmic" | |
514-534 | TRANSMEM | /note="Helical" | |
535-540 | TOPO_DOM | /note="Mitochondrial intermembrane" | |
10-77 | DOMAIN | /note="CARD" | |
10-77 | REGION | /note="Required for interaction with NLRX1" | |
95-297 | REGION | /note="Disordered" | |
143-147 | REGION | /note="Interaction with TRAF2" | |
153-158 | REGION | /note="Interaction with TRAF6" | |
314-358 | REGION | /note="Disordered" | |
373-419 | REGION | /note="Disordered" | |
455-460 | REGION | /note="Interaction with TRAF6" | |
476-507 | REGION | /note="Disordered" | |
102-124 | COMPBIAS | /note="Pro residues" | |
145-166 | COMPBIAS | /note="Polar residues" | |
184-262 | COMPBIAS | /note="Polar residues" | |
314-350 | COMPBIAS | /note="Polar residues" | |
373-389 | COMPBIAS | /note="Polar residues" | |
400-415 | COMPBIAS | /note="Polar residues" | |
493-507 | COMPBIAS | /note="Basic and acidic residues" | |
79-79 | LIPID | /note="S-palmitoyl cysteine" | |
1-533 | DISORDER | predicted by DISOPRED |
MONOMER | |||||||
540 | |||||||
pdb_id | a1 | identity[%]2 | description | ||||
2ms8 | A | 100.0 | MAVS_HUMAN Mitochondrial antiviral-signaling protein | ||||
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue. |
HETERO | |||||||
540 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
4p4h[10] | A | DDX58_HUMAN Probable ATP-dependent RNA helicase DDX58[188 aa] | I | 100.0 /96.9 |
8 /8 |
MAVS_HUMAN Mitochondrial antiviral-signaling protein | |
4p4h[6] | B | DDX58_HUMAN Probable ATP-dependent RNA helicase DDX58[189 aa] | I | 100.0 /96.9 |
7 /7 |
MAVS_HUMAN Mitochondrial antiviral-signaling protein | |
4p4h[3] | C | DDX58_HUMAN Probable ATP-dependent RNA helicase DDX58[189 aa] | I | 100.0 /96.9 |
1 /1 |
MAVS_HUMAN Mitochondrial antiviral-signaling protein | |
4p4h[3] | P | RL40_HUMAN Ubiquitin-60S ribosomal protein L40[71 aa] | K | 100.0 /96.9 |
7 /7 |
MAVS_HUMAN Mitochondrial antiviral-signaling protein | |
7dni[4] | L | UBB_HUMAN Ubiquitin[73 aa] | M | 100.0 /96.9 |
1 /1 |
MAVS_HUMAN Mitochondrial antiviral-signaling protein | |
7dni[5] | E | IFIH1_HUMAN Interferon-induced helicase C domain-containing pr.. | M | 100.0 /96.9 |
5 /5 |
MAVS_HUMAN Mitochondrial antiviral-signaling protein | |
7dni[3] | F | IFIH1_HUMAN Interferon-induced helicase C domain-containing pr.. | M | 100.0 /96.9 |
6 /6 |
MAVS_HUMAN Mitochondrial antiviral-signaling protein | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
HOMO | |||||||
540 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
2ms7[232] | B | MAVS_HUMAN Mitochondrial antiviral-signaling protein[102 aa] | A | 100.0 /100.0 |
5 /5 |
MAVS_HUMAN Mitochondrial antiviral-signaling protein | |
2ms7[18] | D | MAVS_HUMAN Mitochondrial antiviral-signaling protein[102 aa] | A | 100.0 /100.0 |
8 /8 |
MAVS_HUMAN Mitochondrial antiviral-signaling protein | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
PRECIPITANT | |||||||
540 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
2vgq[1] | D |
SO4
SULFATE ION[5 atoms] |
A | 100.0 /98.9 |
5 /5 |
A0A0B1N7A9_ECOLX MAVS_HUMAN Sugar ABC transporter substrate-binding protein,Mi.. | |
2vgq[1] | E |
SO4
SULFATE ION[5 atoms] |
A | 100.0 /98.9 |
2 /2 |
A0A0B1N7A9_ECOLX MAVS_HUMAN Sugar ABC transporter substrate-binding protein,Mi.. | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. |