ID   NS7B_SARS2              Reviewed;          43 AA.
AC   P0DTD8;
DT   22-APR-2020, integrated into UniProtKB/Swiss-Prot.
DT   22-APR-2020, sequence version 1.
DT   02-DEC-2020, entry version 5.
DE   RecName: Full=ORF7b protein;
DE            Short=ORF7b;
DE   AltName: Full=Accessory protein 7b;
GN   ORFNames=7b;
OS   Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2).
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC   Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae;
OC   Betacoronavirus; Sarbecovirus.
OX   NCBI_TaxID=2697049;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=32015508; DOI=10.1038/s41586-020-2008-3;
RA   Wu F., Zhao S., Yu B., Chen Y.-M., Wang W., Song Z.-G., Hu Y., Tao Z.-W.,
RA   Tian J.-H., Pei Y.-Y., Yuan M.-L., Zhang Y.-L., Dai F.-H., Liu Y.,
RA   Wang Q.-M., Zheng J.-J., Xu L., Holmes E.C., Zhang Y.-Z.;
RT   "A new coronavirus associated with human respiratory disease in China.";
RL   Nature 579:265-269(2020).
CC   -!- INTERACTION:
CC       P0DTD8; Q7Z434: MAVS; Xeno; NbExp=2; IntAct=EBI-25475914, EBI-995373;
CC       P0DTD8; Q9H1C4: UNC93B1; Xeno; NbExp=2; IntAct=EBI-25475914, EBI-4401271;
CC   -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000250|UniProtKB:Q7TFA1};
CC       Single-pass membrane protein {ECO:0000250|UniProtKB:Q7TFA1}.
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DR   EMBL; MN908947; -; NOT_ANNOTATED_CDS; Genomic_RNA.
DR   RefSeq; YP_009725318.1; NC_045512.2.
DR   BioGRID; 4383871; 414.
DR   IntAct; P0DTD8; 410.
DR   GeneID; 43740574; -.
DR   Proteomes; UP000464024; Genome.
DR   GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR021532; NS7B_SARS-like.
DR   Pfam; PF11395; bCoV_NS7B; 1.
PE   1: Evidence at protein level;
KW   Host membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..43
FT                   /note="ORF7b protein"
FT                   /id="PRO_0000449799"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   43 AA;  5180 MW;  33DE6E3EBAEF1D9F CRC64;
     MIELSLIDFY LCFLAFLLFL VLIMLIIFWF SLELQDHNET CHA
//