Contact Molecules for Homologous Proteins

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PID QueryLength Homolgous Sequence in PDB UniProt Query TITLE
888849 515 12 P48551(INAR2_HUMAN) RecName: Full=Interferon alpha/beta receptor 2; Short=IFN-R-2; Short=IFN-alpha binding protein; Short=IFN-alpha/beta receptor 2;AltName: Full=Interferon alpha binding protein;AltName: Full=Type I interferon receptor 2;Flags: Precursor;
QUERYSEQ 
MLLSQNAFIFRSLNLVLMVYISLVFGISYDSPDYTDESCTFKISLRNFRSILSWELKNHSIVPTHYTLLYTIMSKPEDLKVVKNCANTTRSFCDLTDEWRSTHEAYVTVLEGFSGNTTLFSCSHNFWLAIDMSFEPPEFEIVGFTNHINV
MVKFPSIVEEELQFDLSLVIEEQSEGIVKKHKPEIKGNMSGNFTYIIDKLIPNTNYCVSVYLEHSDEQAVIKSPLKCTLLPPGQESESAESAKIGGIITVFLIALVLTSTIVTLKWIGYICLRNSLPKVLNFHNFLAWPFPNLPPLEAMD
MVEVIYINRKKKVWDYNYDDESDSDTEAAPRTSGGGYTMHGLTVRPLGQASATSTESQLIDPESEEEPDLPEVDVELPTMPKDSPQQLELLSGPCERRKSPLQDPFPEEDYSSTEGSGGRITFNVDLNSVFLRVLDDEDSDDLEAPLMLS
SHLEEMVDPEDPDNVQSNHLLASGEGTQPTFPSPSSEGLWSEDAPSDQSDTSESDVDLGDGYIMR
[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]

UniProt Feature Tables [P48551(INAR2_HUMAN)]

515
region name description
1-26 SIGNAL
27-515 CHAIN /note="Interferon alpha/beta receptor 2" /id="PRO_0000011006"
27-243 TOPO_DOM /note="Extracellular"
244-264 TRANSMEM /note="Helical"
265-515 TOPO_DOM /note="Cytoplasmic"
318-418 REGION /note="Disordered"
418-444 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)"
455-515 REGION /note="Disordered"
466-497 COMPBIAS /note="Polar residues"
1-515 DISORDER predicted by DISOPRED

MONOMER
515
pdb_id a1 identity[%]2 description
2hym A 100.0 Q15467_HUMAN Soluble IFN alpha/beta receptor 
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue.
HETERO
515 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
2hym[3] B IFNA2_HUMAN Interferon alpha-2[165 aa] A 100.0
/100.0		 19
/19		 Q15467_HUMAN Soluble IFN alpha/beta receptor
3s9d[2] A IFNA2_HUMAN Interferon alpha-2[127 aa] B 100.0
/100.0		 19
/19		 INAR2_HUMAN Interferon alpha/beta receptor 2
3s9d[1] C IFNA2_HUMAN Interferon alpha-2[116 aa] D 100.0
/100.0		 19
/19		 INAR2_HUMAN Interferon alpha/beta receptor 2
3se4[1] B IFNW1_HUMAN Interferon omega-1[143 aa] C 100.0
/100.0		 18
/18		 INAR2_HUMAN Interferon alpha/beta receptor 2
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
METAL
515 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
3s8w[2] D CL
CHLORIDE ION[1 atoms] 		A 100.0
/100.0		 1
/1		 INAR2_HUMAN Interferon alpha/beta receptor 2
3s8w[1] E CL
CHLORIDE ION[1 atoms] 		C 100.0
/100.0		 3
/3		 INAR2_HUMAN Interferon alpha/beta receptor 2
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.