Contact Molecules for Homologous Proteins | ||||
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PID | QueryLength | Homolgous Sequence in PDB | UniProt Query | TITLE |
3947094 | 765 | 12 | Q9ULC8(ZDHC8_HUMAN) | RecName: Full=Palmitoyltransferase ZDHHC8 ; EC=2.3.1.225 ;AltName: Full=Zinc finger DHHC domain-containing protein 8 ; Short=DHHC-8 ;AltName: Full=Zinc finger protein 378; |
QUERYSEQ |
MPRSPGTRLKPAKYIPVATAAALLVGSSTLFFVFTCPWLTRAVSPAVPVYNGIIFLFVLANFSMATFMDPGVFPRADEDEDKEDDFRAPLYKNVDVRGIQVRMKWCATCHFYRPPRCSHCSVCDNCVEDFDHHCPWVNNCIGRRNYRYFF LFLLSLSAHMVGVVAFGLVYVLNHAEGLGAAHTTITMAVMCVAGLFFIPVIGLTGFHVVLVTRGRTTNEQVTGKFRGGVNPFTRGCCGNVEHVLCSPLAPRYVVEPPRLPLAVSLKPPFLRPELLDRAAPLKVKLSDNGLKAGLGRSKSK GSLDRLDEKPLDLGPPLPPKIEAGTFSSDLQTPRPGSAESALSVQRTSPPTPAMYKFRPAFPTGPKVPFCGPGEQVPGPDSLTLGDDSIRSLDFVSEPSLDLPDYGPGGLHAAYPPSPPLSASDAFSGALRSLSLKASSRRGGDHVALQP LRSEGGPPTPHRSIFAPHALPNRNGSLSYDSLLNPGSPGGHACPAHPAVGVAGYHSPYLHPGATGDPPRPLPRSFSPVLGPRPREPSPVRYDNLSRTIMASIQERKDREERERLLRSQADSLFGDSGVYDAPSSYSLQQASVLSEGPRGP ALRYGSRDDLVAGPGFGGARNPALQTSLSSLSSSVSRAPRTSSSSLQADQASSNAPGPRPSSGSHRSPARQGLPSPPGTPHSPSYAGPKAVAFIHTDLPEPPPSLTVQRDHPQLKTPPSKLNGQSPGLARLGPATGPPGPSASPTRHTLV KKVSGVGGTTYEISV |
765 | region | name | description |
1-765 | CHAIN | /note="Palmitoyltransferase ZDHHC8" /id="PRO_0000212877" | |
1-13 | TOPO_DOM | /note="Cytoplasmic" | |
14-34 | TRANSMEM | /note="Helical" | |
35-52 | TOPO_DOM | /note="Lumenal" | |
53-73 | TRANSMEM | /note="Helical" | |
74-148 | TOPO_DOM | /note="Cytoplasmic" | |
149-169 | TRANSMEM | /note="Helical" | |
170-190 | TOPO_DOM | /note="Lumenal" | |
191-211 | TRANSMEM | /note="Helical" | |
212-765 | TOPO_DOM | /note="Cytoplasmic" | |
104-154 | DOMAIN | /note="DHHC" | |
293-352 | REGION | /note="Disordered" | |
509-540 | REGION | /note="Disordered" | |
613-747 | REGION | /note="Disordered" | |
325-350 | COMPBIAS | /note="Polar residues" | |
513-534 | COMPBIAS | /note="Pro residues" | |
622-669 | COMPBIAS | /note="Polar residues" | |
709-723 | COMPBIAS | /note="Polar residues" | |
134-134 | ACT_SITE | /note="S-palmitoyl cysteine intermediate" | |
1-765 | DISORDER | predicted by DISOPRED |
MONOMER | |||||||
765 | |||||||
pdb_id | a1 | identity[%]2 | description | ||||
8hf3 | A | 49.1 | ZDHC9_HUMAN Palmitoyltransferase ZDHHC9 | ||||
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue. |
HETERO | |||||||
765 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
8hf3[1] | B | GOGA7_HUMAN Golgin subfamily A member 7[124 aa] | A | 52.0 /49.1 |
25 /27 |
ZDHC9_HUMAN Palmitoyltransferase ZDHHC9 | |
8hfc[1] | B | ERFD_YEAST Ras modification protein ERF4[222 aa] | A | 20.0 /38.7 |
30 /48 |
ERFB_YEAST Palmitoyltransferase ERF2 | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
COMPOUND | |||||||
765 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
8hf3[1] | I |
PX2
1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE[36 atoms] |
A | 55.6 /49.1 |
9 /11 |
ZDHC9_HUMAN Palmitoyltransferase ZDHHC9 | |
6bms[1] | I |
POV
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoylox.. |
A | 20.0 /39.8 |
5 /8 |
F1QXD3_DANRE Palmitoyltransferase | |
6bml[2] | J |
PAP
3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE[31 atoms] |
B | 40.0 /32.9 |
5 /6 |
ZDH20_HUMAN human DHHC20 palmitoyltransferase | |
6bmm[1] | I |
DYD
(2S,5S)-hexane-2,5-diol[8 atoms] |
A | 0.0 /32.5 |
1 /1 |
ZDH20_HUMAN human DHHC20 palmitoyltransferase | |
6bmm[1] | J |
DYD
(2S,5S)-hexane-2,5-diol[8 atoms] |
A | 0.0 /32.5 |
2 /4 |
ZDH20_HUMAN human DHHC20 palmitoyltransferase | |
6bmm[1] | K |
DYD
(2S,5S)-hexane-2,5-diol[8 atoms] |
A | 0.0 /32.5 |
2 /2 |
ZDH20_HUMAN human DHHC20 palmitoyltransferase | |
6bmm[1] | P |
DYD
(2S,5S)-hexane-2,5-diol[8 atoms] |
B | 0.0 /32.5 |
2 /6 |
ZDH20_HUMAN human DHHC20 palmitoyltransferase | |
7khm[2] | E |
PKZ
Palmitoyl-CoA[65 atoms] |
A | 60.0 /32.3 |
15 /16 |
ZDH20_HUMAN Isoform 4 of Palmitoyltransferase ZDHHC20 | |
7khm[1] | E |
PKZ
Palmitoyl-CoA[65 atoms] |
B | 33.3 /32.3 |
6 /6 |
ZDH20_HUMAN Isoform 4 of Palmitoyltransferase ZDHHC20 | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
METAL | |||||||
765 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
6bml[4] | C |
ZN
ZINC ION[1 atoms] |
A | 100.0 /32.9 |
4 /4 |
ZDH20_HUMAN human DHHC20 palmitoyltransferase | |
6bml[4] | D |
ZN
ZINC ION[1 atoms] |
A | 100.0 /32.9 |
4 /4 |
ZDH20_HUMAN human DHHC20 palmitoyltransferase | |
6bmm[2] | C |
ZN
ZINC ION[1 atoms] |
A | 100.0 /32.5 |
4 /4 |
ZDH20_HUMAN human DHHC20 palmitoyltransferase | |
6bmm[2] | D |
ZN
ZINC ION[1 atoms] |
A | 80.0 /32.5 |
5 /5 |
ZDH20_HUMAN human DHHC20 palmitoyltransferase | |
6bms[2] | C |
ZN
ZINC ION[1 atoms] |
A | 80.0 /39.8 |
5 /5 |
F1QXD3_DANRE Palmitoyltransferase | |
6bms[2] | D |
ZN
ZINC ION[1 atoms] |
A | 100.0 /39.8 |
4 /4 |
F1QXD3_DANRE Palmitoyltransferase | |
7khm[2] | C |
ZN
ZINC ION[1 atoms] |
A | 100.0 /32.3 |
4 /4 |
ZDH20_HUMAN Isoform 4 of Palmitoyltransferase ZDHHC20 | |
7khm[2] | D |
ZN
ZINC ION[1 atoms] |
A | 100.0 /32.3 |
4 /4 |
ZDH20_HUMAN Isoform 4 of Palmitoyltransferase ZDHHC20 | |
8hf3[1] | C |
ZN
ZINC ION[1 atoms] |
A | 100.0 /49.1 |
4 /4 |
ZDHC9_HUMAN Palmitoyltransferase ZDHHC9 | |
8hf3[1] | D |
ZN
ZINC ION[1 atoms] |
A | 100.0 /49.1 |
4 /4 |
ZDHC9_HUMAN Palmitoyltransferase ZDHHC9 | |
8hfc[1] | D |
ZN
ZINC ION[1 atoms] |
A | 100.0 /38.7 |
4 /4 |
ERFB_YEAST Palmitoyltransferase ERF2 | |
8hfc[1] | E |
ZN
ZINC ION[1 atoms] |
A | 100.0 /38.7 |
4 /4 |
ERFB_YEAST Palmitoyltransferase ERF2 | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
HOMO | |||||||
765 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
6bmm[2] | B | ZDH20_HUMAN human DHHC20 palmitoyltransferase[290 aa] | A | 100.0 /32.5 |
1 /2 |
ZDH20_HUMAN human DHHC20 palmitoyltransferase | |
7khm[1] | B | ZDH20_HUMAN Isoform 4 of Palmitoyltransferase ZDHHC20[287 aa] | A | 0.0 /32.3 |
5 /7 |
ZDH20_HUMAN Isoform 4 of Palmitoyltransferase ZDHHC20 | |
7khm[1] | A | ZDH20_HUMAN Isoform 4 of Palmitoyltransferase ZDHHC20[290 aa] | B | 16.7 /32.3 |
6 /7 |
ZDH20_HUMAN Isoform 4 of Palmitoyltransferase ZDHHC20 | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
PRECIPITANT | |||||||
765 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
6bms[1] | E |
LMT
DODECYL-BETA-D-MALTOSIDE[31 atoms] |
A | 50.0 /39.8 |
4 /5 |
F1QXD3_DANRE Palmitoyltransferase | |
6bms[3] | F |
LMT
DODECYL-BETA-D-MALTOSIDE[28 atoms] |
A | 25.0 /39.8 |
4 /4 |
F1QXD3_DANRE Palmitoyltransferase | |
6bml[2] | E |
PLM
PALMITIC ACID[18 atoms] |
A | 80.0 /32.9 |
10 /13 |
ZDH20_HUMAN human DHHC20 palmitoyltransferase | |
6bms[2] | H |
PLM
PALMITIC ACID[18 atoms] |
A | 57.1 /39.8 |
14 /17 |
F1QXD3_DANRE Palmitoyltransferase | |
8hf3[1] | E |
PLM
PALMITIC ACID[15 atoms] |
A | 60.0 /49.1 |
10 /10 |
ZDHC9_HUMAN Palmitoyltransferase ZDHHC9 | |
8hf3[1] | F |
PLM
PALMITIC ACID[17 atoms] |
A | 100.0 /49.1 |
1 /2 |
ZDHC9_HUMAN Palmitoyltransferase ZDHHC9 | |
8hf3[1] | G |
PLM
PALMITIC ACID[17 atoms] |
A | 33.3 /49.1 |
3 /9 |
ZDHC9_HUMAN Palmitoyltransferase ZDHHC9 | |
8hf3[1] | H |
PLM
PALMITIC ACID[17 atoms] |
A | 57.1 /49.1 |
7 /7 |
ZDHC9_HUMAN Palmitoyltransferase ZDHHC9 | |
8hfc[1] | C |
PLM
PALMITIC ACID[15 atoms] |
A | 66.7 /38.7 |
6 /8 |
ERFB_YEAST Palmitoyltransferase ERF2 | |
6bmm[2] | F |
OLB
(2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate[25 .. |
A | 58.3 /32.5 |
12 /13 |
ZDH20_HUMAN human DHHC20 palmitoyltransferase | |
6bml[5] | F |
PO4
PHOSPHATE ION[5 atoms] |
A | 33.3 /32.9 |
3 /3 |
ZDH20_HUMAN human DHHC20 palmitoyltransferase | |
6bmm[5] | E |
PO4
PHOSPHATE ION[5 atoms] |
A | 33.3 /32.5 |
3 /3 |
ZDH20_HUMAN human DHHC20 palmitoyltransferase | |
7khm[1] | F |
PO4
PHOSPHATE ION[5 atoms] |
A | 0.0 /32.3 |
3 /3 |
ZDH20_HUMAN Isoform 4 of Palmitoyltransferase ZDHHC20 | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. |