Contact Molecules for Homologous Proteins


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PID QueryLength Homolgous Sequence in PDB UniProt Query TITLE
2984263 765 12 Q9ULC8(ZDHC8_HUMAN) RecName: Full=Palmitoyltransferase ZDHHC8 ; EC=2.3.1.225 ;AltName: Full=Zinc finger DHHC domain-containing protein 8 ; Short=DHHC-8 ;AltName: Full=Zinc finger protein 378;
QUERYSEQ
MPRSPGTRLKPAKYIPVATAAALLVGSSTLFFVFTCPWLTRAVSPAVPVYNGIIFLFVLANFSMATFMDPGVFPRADEDEDKEDDFRAPLYKNVDVRGIQVRMKWCATCHFYRPPRCSHCSVCDNCVEDFDHHCPWVNNCIGRRNYRYFF
LFLLSLSAHMVGVVAFGLVYVLNHAEGLGAAHTTITMAVMCVAGLFFIPVIGLTGFHVVLVTRGRTTNEQVTGKFRGGVNPFTRGCCGNVEHVLCSPLAPRYVVEPPRLPLAVSLKPPFLRPELLDRAAPLKVKLSDNGLKAGLGRSKSK
GSLDRLDEKPLDLGPPLPPKIEAGTFSSDLQTPRPGSAESALSVQRTSPPTPAMYKFRPAFPTGPKVPFCGPGEQVPGPDSLTLGDDSIRSLDFVSEPSLDLPDYGPGGLHAAYPPSPPLSASDAFSGALRSLSLKASSRRGGDHVALQP
LRSEGGPPTPHRSIFAPHALPNRNGSLSYDSLLNPGSPGGHACPAHPAVGVAGYHSPYLHPGATGDPPRPLPRSFSPVLGPRPREPSPVRYDNLSRTIMASIQERKDREERERLLRSQADSLFGDSGVYDAPSSYSLQQASVLSEGPRGP
ALRYGSRDDLVAGPGFGGARNPALQTSLSSLSSSVSRAPRTSSSSLQADQASSNAPGPRPSSGSHRSPARQGLPSPPGTPHSPSYAGPKAVAFIHTDLPEPPPSLTVQRDHPQLKTPPSKLNGQSPGLARLGPATGPPGPSASPTRHTLV
KKVSGVGGTTYEISV
[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]

UniProt Feature Tables [Q9ULC8(ZDHC8_HUMAN)]

765
region name description
1-765 CHAIN /note="Palmitoyltransferase ZDHHC8" /id="PRO_0000212877"
1-13 TOPO_DOM /note="Cytoplasmic"
14-34 TRANSMEM /note="Helical"
35-52 TOPO_DOM /note="Lumenal"
53-73 TRANSMEM /note="Helical"
74-148 TOPO_DOM /note="Cytoplasmic"
149-169 TRANSMEM /note="Helical"
170-190 TOPO_DOM /note="Lumenal"
191-211 TRANSMEM /note="Helical"
212-765 TOPO_DOM /note="Cytoplasmic"
104-154 DOMAIN /note="DHHC"
293-352 REGION /note="Disordered"
509-540 REGION /note="Disordered"
613-747 REGION /note="Disordered"
325-350 COMPBIAS /note="Polar residues"
513-534 COMPBIAS /note="Pro residues"
622-669 COMPBIAS /note="Polar residues"
709-723 COMPBIAS /note="Polar residues"
134-134 ACT_SITE /note="S-palmitoyl cysteine intermediate"
1-765 DISORDER predicted by DISOPRED

MONOMER
765
pdb_id a1 identity[%]2 description
8hf3 A 49.1 ZDHC9_HUMAN Palmitoyltransferase ZDHHC9
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue.
HETERO
765 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
8hf3[1] B GOGA7_HUMAN Golgin subfamily A member 7[124 aa] A 52.0
/49.1
25
/27
ZDHC9_HUMAN Palmitoyltransferase ZDHHC9
8hfc[1] B ERFD_YEAST Ras modification protein ERF4[222 aa] A 20.0
/38.7
30
/48
ERFB_YEAST Palmitoyltransferase ERF2
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
COMPOUND
765 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
8hf3[1] I PX2
1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE[36 atoms]
A 55.6
/49.1
9
/11
ZDHC9_HUMAN Palmitoyltransferase ZDHHC9
6bms[1] I POV
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoylox..
A 20.0
/39.8
5
/8
F1QXD3_DANRE Palmitoyltransferase
6bml[2] J PAP
3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE[31 atoms]
B 40.0
/32.9
5
/6
ZDH20_HUMAN human DHHC20 palmitoyltransferase
6bmm[1] I DYD
(2S,5S)-hexane-2,5-diol[8 atoms]
A 0.0
/32.5
1
/1
ZDH20_HUMAN human DHHC20 palmitoyltransferase
6bmm[1] J DYD
(2S,5S)-hexane-2,5-diol[8 atoms]
A 0.0
/32.5
2
/4
ZDH20_HUMAN human DHHC20 palmitoyltransferase
6bmm[1] K DYD
(2S,5S)-hexane-2,5-diol[8 atoms]
A 0.0
/32.5
2
/2
ZDH20_HUMAN human DHHC20 palmitoyltransferase
6bmm[1] P DYD
(2S,5S)-hexane-2,5-diol[8 atoms]
B 0.0
/32.5
2
/6
ZDH20_HUMAN human DHHC20 palmitoyltransferase
7khm[2] E PKZ
Palmitoyl-CoA[65 atoms]
A 60.0
/32.3
15
/16
ZDH20_HUMAN Isoform 4 of Palmitoyltransferase ZDHHC20
7khm[1] E PKZ
Palmitoyl-CoA[65 atoms]
B 33.3
/32.3
6
/6
ZDH20_HUMAN Isoform 4 of Palmitoyltransferase ZDHHC20
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
METAL
765 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
6bml[4] C ZN
ZINC ION[1 atoms]
A 100.0
/32.9
4
/4
ZDH20_HUMAN human DHHC20 palmitoyltransferase
6bml[4] D ZN
ZINC ION[1 atoms]
A 100.0
/32.9
4
/4
ZDH20_HUMAN human DHHC20 palmitoyltransferase
6bmm[2] C ZN
ZINC ION[1 atoms]
A 100.0
/32.5
4
/4
ZDH20_HUMAN human DHHC20 palmitoyltransferase
6bmm[2] D ZN
ZINC ION[1 atoms]
A 80.0
/32.5
5
/5
ZDH20_HUMAN human DHHC20 palmitoyltransferase
6bms[2] C ZN
ZINC ION[1 atoms]
A 80.0
/39.8
5
/5
F1QXD3_DANRE Palmitoyltransferase
6bms[2] D ZN
ZINC ION[1 atoms]
A 100.0
/39.8
4
/4
F1QXD3_DANRE Palmitoyltransferase
7khm[2] C ZN
ZINC ION[1 atoms]
A 100.0
/32.3
4
/4
ZDH20_HUMAN Isoform 4 of Palmitoyltransferase ZDHHC20
7khm[2] D ZN
ZINC ION[1 atoms]
A 100.0
/32.3
4
/4
ZDH20_HUMAN Isoform 4 of Palmitoyltransferase ZDHHC20
8hf3[1] C ZN
ZINC ION[1 atoms]
A 100.0
/49.1
4
/4
ZDHC9_HUMAN Palmitoyltransferase ZDHHC9
8hf3[1] D ZN
ZINC ION[1 atoms]
A 100.0
/49.1
4
/4
ZDHC9_HUMAN Palmitoyltransferase ZDHHC9
8hfc[1] D ZN
ZINC ION[1 atoms]
A 100.0
/38.7
4
/4
ERFB_YEAST Palmitoyltransferase ERF2
8hfc[1] E ZN
ZINC ION[1 atoms]
A 100.0
/38.7
4
/4
ERFB_YEAST Palmitoyltransferase ERF2
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
HOMO
765 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
6bmm[2] B ZDH20_HUMAN human DHHC20 palmitoyltransferase[290 aa] A 100.0
/32.5
1
/2
ZDH20_HUMAN human DHHC20 palmitoyltransferase
7khm[1] B ZDH20_HUMAN Isoform 4 of Palmitoyltransferase ZDHHC20[287 aa] A 0.0
/32.3
5
/7
ZDH20_HUMAN Isoform 4 of Palmitoyltransferase ZDHHC20
7khm[1] A ZDH20_HUMAN Isoform 4 of Palmitoyltransferase ZDHHC20[290 aa] B 16.7
/32.3
6
/7
ZDH20_HUMAN Isoform 4 of Palmitoyltransferase ZDHHC20
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
PRECIPITANT
765 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
6bms[1] E LMT
DODECYL-BETA-D-MALTOSIDE[31 atoms]
A 50.0
/39.8
4
/5
F1QXD3_DANRE Palmitoyltransferase
6bms[3] F LMT
DODECYL-BETA-D-MALTOSIDE[28 atoms]
A 25.0
/39.8
4
/4
F1QXD3_DANRE Palmitoyltransferase
6bml[2] E PLM
PALMITIC ACID[18 atoms]
A 80.0
/32.9
10
/13
ZDH20_HUMAN human DHHC20 palmitoyltransferase
6bms[2] H PLM
PALMITIC ACID[18 atoms]
A 57.1
/39.8
14
/17
F1QXD3_DANRE Palmitoyltransferase
8hf3[1] E PLM
PALMITIC ACID[15 atoms]
A 60.0
/49.1
10
/10
ZDHC9_HUMAN Palmitoyltransferase ZDHHC9
8hf3[1] F PLM
PALMITIC ACID[17 atoms]
A 100.0
/49.1
1
/2
ZDHC9_HUMAN Palmitoyltransferase ZDHHC9
8hf3[1] G PLM
PALMITIC ACID[17 atoms]
A 33.3
/49.1
3
/9
ZDHC9_HUMAN Palmitoyltransferase ZDHHC9
8hf3[1] H PLM
PALMITIC ACID[17 atoms]
A 57.1
/49.1
7
/7
ZDHC9_HUMAN Palmitoyltransferase ZDHHC9
8hfc[1] C PLM
PALMITIC ACID[15 atoms]
A 66.7
/38.7
6
/8
ERFB_YEAST Palmitoyltransferase ERF2
6bmm[2] F OLB
(2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate[25 ..
A 58.3
/32.5
12
/13
ZDH20_HUMAN human DHHC20 palmitoyltransferase
6bml[5] F PO4
PHOSPHATE ION[5 atoms]
A 33.3
/32.9
3
/3
ZDH20_HUMAN human DHHC20 palmitoyltransferase
6bmm[5] E PO4
PHOSPHATE ION[5 atoms]
A 33.3
/32.5
3
/3
ZDH20_HUMAN human DHHC20 palmitoyltransferase
7khm[1] F PO4
PHOSPHATE ION[5 atoms]
A 0.0
/32.3
3
/3
ZDH20_HUMAN Isoform 4 of Palmitoyltransferase ZDHHC20
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.