Contact Molecules for Homologous Proteins


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PID QueryLength Homolgous Sequence in PDB UniProt Query TITLE
260635 296 164 Q99836(MYD88_HUMAN) RecName: Full=Myeloid differentiation primary response protein MyD88 ;
QUERYSEQ
MAAGGPGAGSAAPVSSTSSLPLAALNMRVRRRLSLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQADPTGRLLDAWQGRPGASVGRLLELLTKLGRDDVLLELGPSIEEDCQKYILKQQQEEAEKPLQVAAVDSSVPRTAELAGITTL
DDPLGHMPERFDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRCRRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPSILRFITVCDYTNPCTKSWFWTRLAKALSLP
[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]

UniProt Feature Tables [Q99836(MYD88_HUMAN)]

296
region name description
1-296 CHAIN /note="Myeloid differentiation primary response protein MyD88" /id="PRO_0000096666"
54-109 DOMAIN /note="Death"
159-293 DOMAIN /note="TIR"
110-155 REGION /note="Intermediate domain"
1-16 DISORDER predicted by DISOPRED

MONOMER
296
pdb_id a1 identity[%]2 description
2js7 A 100.0 MYD88_HUMAN Myeloid differentiation primary response protein MyD88
6i3n K 100.0 H0Y4G9_HUMAN Myeloid differentiation primary response protein MyD88
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue.
HETERO
296 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
3mop[4] G IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4[107 aa].. C 100.0
/100.0
9
/9
MYD88_HUMAN Myeloid differentiation primary response protein M..
3mop[3] G IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4[107 aa].. D 100.0
/100.0
6
/6
MYD88_HUMAN Myeloid differentiation primary response protein M..
3mop[1] G IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4[107 aa].. F 100.0
/100.0
7
/7
MYD88_HUMAN Myeloid differentiation primary response protein M..
4w8h[1] B hexa-His tag[4 aa] A 50.0
/33.1
4
/5
A6M946_HYDVU Toll-receptor-related 2
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
METAL
296 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
4w8h[1] C CL
CHLORIDE ION[1 atoms]
A 50.0
/33.1
2
/2
A6M946_HYDVU Toll-receptor-related 2
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
HOMO
296 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
3mop[5] B MYD88_HUMAN Myeloid differentiation primary response protein M.. A 100.0
/100.0
5
/5
MYD88_HUMAN Myeloid differentiation primary response protein M..
3mop[63] D MYD88_HUMAN Myeloid differentiation primary response protein M.. A 100.0
/100.0
12
/12
MYD88_HUMAN Myeloid differentiation primary response protein M..
3mop[2] E MYD88_HUMAN Myeloid differentiation primary response protein M.. A 100.0
/100.0
11
/11
MYD88_HUMAN Myeloid differentiation primary response protein M..
3mop[3] A MYD88_HUMAN Myeloid differentiation primary response protein M.. D 100.0
/100.0
10
/10
MYD88_HUMAN Myeloid differentiation primary response protein M..
6i3n[9] B H0Y4G9_HUMAN Myeloid differentiation primary response protein M.. A 100.0
/100.0
9
/9
H0Y4G9_HUMAN Myeloid differentiation primary response protein M..
8w8m[68] B MYD88_HUMAN Myeloid differentiation primary response protein M.. A 100.0
/100.0
4
/4
MYD88_HUMAN Myeloid differentiation primary response protein M..
8w8m[239] C MYD88_HUMAN Myeloid differentiation primary response protein M.. A 100.0
/100.0
3
/3
MYD88_HUMAN Myeloid differentiation primary response protein M..
8w8m[99] P MYD88_HUMAN Myeloid differentiation primary response protein M.. A 100.0
/100.0
12
/12
MYD88_HUMAN Myeloid differentiation primary response protein M..
1fyw[2] A TLR2_HUMAN TOLL-LIKE RECEPTOR 2[149 aa] A 26.7
/31.0
15
/16
TLR2_HUMAN TOLL-LIKE RECEPTOR 2
4om7[2] B TLR6_HUMAN Toll-like receptor 6[143 aa] A 25.0
/30.8
8
/12
TLR6_HUMAN Toll-like receptor 6
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.