Contact Molecules for Homologous Proteins | ||||
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PID | QueryLength | Homolgous Sequence in PDB | UniProt Query | TITLE |
890320 | 503 | 77 | Q92985(IRF7_HUMAN) | RecName: Full=Interferon regulatory factor 7; Short=IRF-7; |
QUERYSEQ |
MALAPERAAPRVLFGEWLLGEISSGCYEGLQWLDEARTCFRVPWKHFARKDLSEADARIFKAWAVARGRWPPSSRGGGPPPEAETAERAGWKTNFRCALRSTRRFVMLRDNSGDPADPHKVYALSRELCWREGPGTDQTEAEAPAAVPPP QGGPPGPFLAHTHAGLQAPGPLPAPAGDKGDLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGGPGLPAGELYGWAVETTPSPGPQPAALTTGEAAAPESPHQAEPYLSPSPSACTAVQEPSPGALDVTIMYKGRTV LQKVVGHPSCTFLYGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTEELLRHVAPGLHLELRGPQLWARRMGKCKVYWEVGGPPGSASPSTPACLLPRNCDTPIFDFRVFFQELVEFRARQRRGSPRYTIYLGFGQDLSAGRPKEKSLVL VKLEPWLCRVHLEGTQREGVSSLDSSSLSLCLSSANSLYDDIECFLMELEQPA |
503 |
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region | name | description |
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1-503 | CHAIN | /note="Interferon regulatory factor 7" /id="PRO_0000154562" |
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11-126 | DNA_BIND | /note="IRF tryptophan pentad repeat" |
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69-88 | REGION | /note="Disordered" |
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133-156 | REGION | /note="Disordered" |
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242-277 | REGION | /note="Disordered" |
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284-456 | REGION | /note="Necessary for the interaction with NMI" |
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1-503 | DISORDER | predicted by DISOPRED |
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503 | |||||||
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pdb_id | a1 | identity[%]2 | description | |||
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C | 99.1 | TF65_HUMAN IRF7_HUMAN IRF3_HUMAN Transcription factor p65/Interferon regulatory factor 7/Interferon regulatory factor 3 fusion protein | |||
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A | 33.3 | IRF5_HUMAN Interferon regulatory factor 5 | |||
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B | 30.8 | IRF3_HUMAN Interferon regulatory factor 3 | |||
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue. |
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503 | pdb_id | contact mol | homologue | ||||
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a3 | description | a4 | identity[%]5 | Ncon6 | description | |
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D | NFKB1_HUMAN Nuclear factor NF-kappa-B p105 subunit[314 aa] | C | 100.0 /99.1 |
3 /19 |
TF65_HUMAN IRF7_HUMAN IRF3_HUMAN Transcription factor p65/Interferon regulatory fac.. |
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F | ATF2_HUMAN Cyclic-AMP-dependent transcription factor ATF-2[61.. | C | 66.7 /45.2 |
3 /3 |
IRF3_HUMAN Interferon regulatory factor 3 |
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B | STING_HUMAN Stimulator of interferon genes protein[10 aa] | D | 46.7 /30.8 |
15 /15 |
IRF3_HUMAN Interferon regulatory factor 3 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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C | STING_HUMAN Stimulator of interferon genes protein[4 aa] | D | 50.0 /30.8 |
2 /2 |
IRF3_HUMAN Interferon regulatory factor 3 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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C | STING_HUMAN Stimulator of interferon genes protein[4 aa] | E | 40.0 /30.8 |
5 /5 |
IRF3_HUMAN Interferon regulatory factor 3 |
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A | STING_HUMAN Stimulator of interferon genes protein[21 aa] | E | 46.7 /30.8 |
15 /15 |
IRF3_HUMAN Interferon regulatory factor 3 |
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C | MAVS peptide[14 aa] | A | 46.2 /30.8 |
13 /13 |
IRF3_HUMAN Interferon regulatory factor 3 |
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D | MAVS peptide[16 aa] | B | 41.7 /30.8 |
12 /12 |
IRF3_HUMAN Interferon regulatory factor 3 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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B | Phosphorylated TRIF peptide[14 aa] | A | 31.2 /30.8 |
16 /16 |
IRF3_HUMAN Interferon regulatory factor 3 |
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A | Rotavirus NSP1 peptide[10 aa] | B | 47.1 /30.8 |
17 /17 |
IRF3_HUMAN Interferon regulatory factor 3 |
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A | Rotavirus NSP1 peptide[10 aa] | E | 35.7 /30.8 |
14 /14 |
IRF3_HUMAN Interferon regulatory factor 3 |
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D | Rotavirus NSP1 peptide[10 aa] | F | 100.0 /30.8 |
1 /1 |
IRF3_HUMAN Interferon regulatory factor 3 |
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B | CBP_HUMAN CREB-binding protein[47 aa] | A | 13.3 /31.3 |
15 /18 |
IRF3_HUMAN Interferon regulatory factor 3 |
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B | CBP_HUMAN CREB-binding protein[42 aa] | A | 20.0 /30.6 |
15 /18 |
IRF3_HUMAN Interferon regulatory factor 3 |
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D | CBP_HUMAN CREB-binding protein[42 aa] | A | 0.0 /30.6 |
2 /3 |
IRF3_HUMAN Interferon regulatory factor 3 |
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D | CBP_HUMAN CREB-binding protein[37 aa] | A | 0.0 /31.6 |
1 /1 |
IRF3_MOUSE Interferon regulatory factor 3 |
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D | CBP_HUMAN CREB-binding protein[37 aa] | C | 14.3 /30.7 |
14 /17 |
IRF3_MOUSE Interferon regulatory factor 3 |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
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503 | pdb_id | contact mol | homologue | ||||
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a3 | description | a4 | identity[%]5 | Ncon6 | description | |
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A | 36-MER | C | 100.0 /99.1 |
10 /34 |
TF65_HUMAN IRF7_HUMAN IRF3_HUMAN Transcription factor p65/Interferon regulatory fac.. |
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B | 34-MER | C | 93.8 /99.1 |
16 /36 |
TF65_HUMAN IRF7_HUMAN IRF3_HUMAN Transcription factor p65/Interferon regulatory fac.. |
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A | Interferon-Stimulated Response Elements | C | 70.0 /46.0 |
10 /10 |
IRF4_HUMAN Interferon regulatory factor 4 |
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B | Interferon-Stimulated Response Elements | C | 33.3 /46.0 |
6 /9 |
IRF4_HUMAN Interferon regulatory factor 4 |
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F | DNA (5'-D(*GP*CP*TP*TP*TP*CP*TP*CP*GP*GP*TP*TP*TP*.. | G | 50.0 /47.0 |
8 /11 |
Q99419_HUMAN ICSAT transcription factor |
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A | PRDIII-I region of human interferon-B promoter str.. | C | 50.0 /46.9 |
12 /12 |
IRF3_HUMAN Interferon regulatory factor 3 |
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B | PRDIII-I region of human interferon-B promoter str.. | C | 50.0 /46.9 |
12 /13 |
IRF3_HUMAN Interferon regulatory factor 3 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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B | DNA (5'-D(P*AP*AP*TP*AP*AP*AP*AP*GP*AP*AP*AP*CP*CP.. | A | 66.7 /45.6 |
9 /9 |
IRF4_HUMAN Interferon regulatory factor 4 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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C | DNA (5'-D(P*TP*TP*TP*AP*CP*TP*TP*TP*CP*GP*GP*TP*TP.. | A | 40.0 /45.6 |
10 /13 |
IRF4_HUMAN Interferon regulatory factor 4 |
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C | DNA (5'-D(P*TP*GP*TP*AP*CP*TP*TP*TP*CP*GP*GP*TP*TP.. | A | 55.6 /45.6 |
9 /13 |
IRF4_HUMAN Interferon regulatory factor 4 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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D | DNA (5'-D(P*AP*TP*AP*AP*CP*TP*GP*AP*AP*AP*CP*CP*GP.. | A | 66.7 /45.6 |
12 /12 |
IRF4_HUMAN Interferon regulatory factor 4 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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C | DNA (5'-D(P*TP*CP*AP*AP*CP*TP*GP*AP*AP*AP*CP*CP*GP.. | A | 63.6 /45.6 |
11 /11 |
IRF4_HUMAN Interferon regulatory factor 4 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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D | DNA (5'-D(P*AP*GP*CP*TP*TP*TP*CP*TP*CP*GP*GP*TP*TP.. | A | 20.0 /45.6 |
10 /13 |
IRF4_HUMAN Interferon regulatory factor 4 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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A | 31-MER | C | 55.6 /45.2 |
9 /9 |
IRF3_HUMAN Interferon regulatory factor 3 |
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B | 31-MER | C | 43.8 /45.2 |
16 /17 |
IRF3_HUMAN Interferon regulatory factor 3 |
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A | interferon-b enhancer | C | 50.0 /45.2 |
12 /12 |
IRF3_HUMAN Interferon regulatory factor 3 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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B | interferon-b enhancer | C | 40.0 /45.2 |
15 /16 |
IRF3_HUMAN Interferon regulatory factor 3 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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A | DNA (26-MER) | C | 65.0 /39.5 |
20 /22 |
IRF1_MOUSE PROTEIN (INTERFERON REGULATORY FACTOR 1) |
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B | DNA (26-MER) | C | 100.0 /39.5 |
1 /2 |
IRF1_MOUSE PROTEIN (INTERFERON REGULATORY FACTOR 1) |
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F | DNA (5'-D(*TP*TP*CP*AP*CP*TP*TP*TP*CP*AP*CP*(5IU)P.. | G | 50.0 /38.7 |
10 /10 |
IRF2_MOUSE INTERFERON REGULATORY FACTOR 2 |
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A | DNA (5'-D(P*AP*AP*GP*TP*GP*AP*AP*AP*GP*(5IU)P*GP*A.. | H | 60.0 /38.7 |
10 /11 |
IRF2_MOUSE INTERFERON REGULATORY FACTOR 2 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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E | DNA (5'-D(*TP*TP*CP*AP*CP*TP*TP*TP*CP*AP*CP*(5IU)P.. | I | 50.0 /38.7 |
10 /10 |
IRF2_MOUSE INTERFERON REGULATORY FACTOR 2 |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
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503 | pdb_id | contact mol | homologue | ||||
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
a3 | description | a4 | identity[%]5 | Ncon6 | description | |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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H |
CL
|
A | 75.0 /45.8 |
4 /4 |
Q7Z5G6_HUMAN IRF3 protein |
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I |
CL
|
A | 0.0 /45.8 |
1 /1 |
Q7Z5G6_HUMAN IRF3 protein |
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M |
CL
|
A | 25.0 /45.8 |
4 /4 |
Q7Z5G6_HUMAN IRF3 protein |
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C |
CL
|
A | 16.7 /30.1 |
6 /6 |
Q5SUZ4_MOUSE Interferon regulatory factor 4 |
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D |
CL
|
A | 16.7 /30.1 |
6 /6 |
Q5SUZ4_MOUSE Interferon regulatory factor 4 |
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E |
CL
|
A | 0.0 /30.1 |
2 /2 |
Q5SUZ4_MOUSE Interferon regulatory factor 4 |
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B |
CL
|
A | 100.0 /45.9 |
1 /1 |
IRF4_HUMAN Interferon regulatory factor 4 |
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D |
NA
|
A | 75.0 /74.6 |
4 /4 |
IRF7_MOUSE Interferon regulatory factor 7 |
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K |
NA
|
A | 50.0 /45.8 |
2 /2 |
Q7Z5G6_HUMAN IRF3 protein |
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L |
NA
|
A | 40.0 /45.8 |
5 /5 |
Q7Z5G6_HUMAN IRF3 protein |
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D |
ZN
|
A | 0.0 /45.8 |
2 /2 |
Q7Z5G6_HUMAN IRF3 protein |
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E |
ZN
|
A | 0.0 /45.8 |
2 /2 |
Q7Z5G6_HUMAN IRF3 protein |
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F |
ZN
|
A | 50.0 /45.8 |
2 /2 |
Q7Z5G6_HUMAN IRF3 protein |
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G |
ZN
|
A | 25.0 /45.8 |
4 /4 |
Q7Z5G6_HUMAN IRF3 protein |
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M |
K
|
G | 0.0 /38.7 |
4 /4 |
IRF2_MOUSE INTERFERON REGULATORY FACTOR 2 |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
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503 | pdb_id | contact mol | homologue | ||||
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
a3 | description | a4 | identity[%]5 | Ncon6 | description | |
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E | IRF4_HUMAN Interferon regulatory factor 4[112 aa] | D | 100.0 /45.6 |
2 /2 |
IRF4_HUMAN Interferon regulatory factor 4 |
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D | IRF4_HUMAN Interferon regulatory factor 4[109 aa] | E | 50.0 /45.6 |
2 /2 |
IRF4_HUMAN Interferon regulatory factor 4 |
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E | IRF3_HUMAN Interferon regulatory factor 3[110 aa] | C | 33.3 /45.2 |
3 /3 |
IRF3_HUMAN Interferon regulatory factor 3 |
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C | IRF3_HUMAN Interferon regulatory factor 3[110 aa] | E | 0.0 /45.2 |
3 /3 |
IRF3_HUMAN Interferon regulatory factor 3 |
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C | IRF3_HUMAN Interferon regulatory factor 3[98 aa] | E | 0.0 /45.2 |
1 /1 |
IRF3_HUMAN Interferon regulatory factor 3 |
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A | IRF5_HUMAN Interferon regulatory factor 5[236 aa] | A | 36.0 /33.3 |
50 /62 |
IRF5_HUMAN Interferon regulatory factor 5 |
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B | IRF3_HUMAN Interferon regulatory factor 3[239 aa] | A | 44.4 /30.8 |
9 /9 |
IRF3_HUMAN Interferon regulatory factor 3 |
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A | IRF3_HUMAN Interferon regulatory factor 3[239 aa] | B | 20.0 /30.8 |
10 /10 |
IRF3_HUMAN Interferon regulatory factor 3 |
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E | IRF3_HUMAN Interferon regulatory factor 3[233 aa] | D | 31.6 /30.8 |
19 /20 |
IRF3_HUMAN Interferon regulatory factor 3 |
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C | IRF3_MOUSE Interferon regulatory factor 3[194 aa] | A | 29.7 /31.6 |
37 /38 |
IRF3_MOUSE Interferon regulatory factor 3 |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
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503 | pdb_id | contact mol | homologue | ||||
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
a3 | description | a4 | identity[%]5 | Ncon6 | description | |
![]() ![]() ![]() ![]() ![]() |
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F |
EDO
|
B | 0.0 /73.9 |
2 /2 |
IRF7_MOUSE Interferon regulatory factor 7 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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G |
EDO
|
B | 100.0 /73.9 |
3 /3 |
IRF7_MOUSE Interferon regulatory factor 7 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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J |
EDO
|
C | 66.7 /73.9 |
3 /5 |
IRF7_MOUSE Interferon regulatory factor 7 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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C |
PO4
|
A | 0.0 /30.8 |
4 /4 |
IRF3_HUMAN Interferon regulatory factor 3 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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D |
PO4
|
A | 0.0 /30.8 |
3 /6 |
IRF3_HUMAN Interferon regulatory factor 3 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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E |
PO4
|
A | 0.0 /30.8 |
3 /3 |
IRF3_HUMAN Interferon regulatory factor 3 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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I |
PO4
|
B | 33.3 /30.8 |
3 /4 |
IRF3_HUMAN Interferon regulatory factor 3 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
![]() |
J |
PO4
|
B | 25.0 /30.8 |
4 /4 |
IRF3_HUMAN Interferon regulatory factor 3 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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C |
PO4
|
B | 75.0 /30.8 |
4 /4 |
IRF3_HUMAN Interferon regulatory factor 3 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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D |
PO4
|
B | 33.3 /30.8 |
3 /3 |
IRF3_HUMAN Interferon regulatory factor 3 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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E |
PO4
|
B | 0.0 /30.8 |
2 /2 |
IRF3_HUMAN Interferon regulatory factor 3 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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E |
PO4
|
B | 0.0 /45.6 |
2 /2 |
IRF4_HUMAN Interferon regulatory factor 4 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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E |
ACY
|
A | 60.0 /31.8 |
5 /5 |
IRF3_HUMAN Interferon regulatory factor 3 |
![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
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F |
MPD
|
A | 20.0 /31.8 |
5 /5 |
IRF3_HUMAN Interferon regulatory factor 3 |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. |