Contact Molecules for Homologous Proteins


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PID QueryLength Homolgous Sequence in PDB UniProt Query TITLE
2676554 163 94 Q96PD4(IL17F_HUMAN) RecName: Full=Interleukin-17F; Short=IL-17F;AltName: Full=Cytokine ML-1;Flags: Precursor;
QUERYSEQ
MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTV
GCTCVTPVIHHVQ
[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]

UniProt Feature Tables [Q96PD4(IL17F_HUMAN)]

163
region name description
1-30 SIGNAL
31-163 CHAIN /note="Interleukin-17F" /id="PRO_0000015432"
1-163 DISORDER predicted by DISOPRED

MONOMER
163
pdb_id a1 identity[%]2 description
6hgo C 100.0 IL17F_HUMAN Interleukin-17F
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue.
HETERO
163 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
5n92[3] A IL17_HUMAN Interleukin-17A[109 aa] B 100.0
/100.0
58
/58
IL17F_HUMAN Interleukin-17F
6ppg[2] C Fab MCAF5352A heavy chain[223 aa] A 100.0
/100.0
3
/3
IL17F_HUMAN Interleukin-17F
6ppg[2] D Fab MCAF5352A heavy chain[226 aa] A 100.0
/100.0
7
/7
IL17F_HUMAN Interleukin-17F
8dy1[2] C scFv CAT2200 LH[228 aa] A 57.1
/61.1
7
/7
IL17_HUMAN Interleukin-17A
5n7w[2] B Antibody Fragment Light Chain[210 aa] E 100.0
/64.6
1
/4
IL17_HUMAN Interleukin-17A
5n7w[2] D Antibody Fragment Light Chain[211 aa] E 55.6
/64.6
9
/15
IL17_HUMAN Interleukin-17A
5n7w[2] C Antibody Fragment Heavy Chain[216 aa] E 0.0
/64.6
1
/4
IL17_HUMAN Interleukin-17A
2vxs[6] E FAB FRAGMENT[216 aa] A 40.0
/64.2
5
/6
IL17_HUMAN INTERLEUKIN-17A
2vxs[6] F FAB FRAGMENT[221 aa] A 66.7
/64.2
6
/6
IL17_HUMAN INTERLEUKIN-17A
5hhv[2] C CAT-2000 FAB heavy chain[220 aa] A 70.0
/60.0
10
/10
IL17_HUMAN Interleukin-17A
5hhv[2] C CAT-2000 FAB heavy chain[220 aa] A 40.0
/60.0
5
/5
IL17_HUMAN Interleukin-17A
5hi3[6] C CAT-2000 FAB heavy chain[220 aa] A 75.0
/64.4
8
/8
IL17_HUMAN Interleukin-17A
5hi3[6] E CAT-2000 FAB heavy chain[220 aa] A 40.0
/64.4
5
/7
IL17_HUMAN Interleukin-17A
2vxs[6] J FAB FRAGMENT[215 aa] A 40.0
/64.2
5
/5
IL17_HUMAN INTERLEUKIN-17A
5hhv[2] E CAT-2000 FAB light chain[213 aa] A 40.0
/60.0
5
/5
IL17_HUMAN Interleukin-17A
5hi3[6] D CAT-2000 FAB light chain[213 aa] A 40.0
/64.4
5
/5
IL17_HUMAN Interleukin-17A
5hhv[2] D IL-17A peptide inhibitor[14 aa] A 66.7
/60.0
6
/6
IL17_HUMAN Interleukin-17A
5hhv[2] D IL-17A peptide inhibitor[14 aa] A 75.0
/60.0
8
/8
IL17_HUMAN Interleukin-17A
5hhx[2] D IL-17A peptide inhibitor[14 aa] A 66.7
/61.6
6
/6
IL17_HUMAN Interleukin-17A
5hhx[2] D IL-17A peptide inhibitor[14 aa] A 77.8
/61.6
9
/9
IL17_HUMAN Interleukin-17A
5hi3[3] F synthetic IL-17A peptide inhibitor[14 aa] A 71.4
/64.4
7
/15
IL17_HUMAN Interleukin-17A
5hi3[3] F synthetic IL-17A peptide inhibitor[14 aa] B 60.0
/64.3
5
/5
IL17_HUMAN Interleukin-17A
6wio[4] A Fab Heavy chain[230 aa] C 60.0
/61.4
10
/10
IL17_HUMAN Interleukin-17A
6wio[4] A Fab Heavy chain[230 aa] C 33.3
/61.4
3
/4
IL17_HUMAN Interleukin-17A
5vb9[4] C Peptide inhibitor[15 aa] A 33.3
/63.2
9
/10
IL17_HUMAN Interleukin-17A
5vb9[4] C Peptide inhibitor[15 aa] A 80.0
/63.2
5
/9
IL17_HUMAN Interleukin-17A
4qhu[2] A Fab6785 light chain[209 aa] E 47.4
/56.2
19
/19
IL17_HUMAN Interleukin-17A
4qhu[1] A Fab6785 light chain[209 aa] F 100.0
/62.5
1
/1
IL17_HUMAN Interleukin-17A
4qhu[2] B Fab6785 heavy chain[211 aa] E 25.0
/56.2
8
/8
IL17_HUMAN Interleukin-17A
8dy5[2] A spFv CAT2200 LH[244 aa] C 66.7
/60.7
9
/9
IL17_HUMAN Interleukin-17A
7wkx[2] B Heavy chain of HB0017 Fab[212 aa] E 75.0
/63.1
8
/10
IL17_HUMAN Interleukin-17A
7wkx[2] D Light chain of HB0017 Fab[216 aa] E 40.0
/63.1
5
/5
IL17_HUMAN Interleukin-17A
6ppg[2] B Fab MCAF5352A light chain[212 aa] A 100.0
/100.0
1
/1
IL17F_HUMAN Interleukin-17F
6ppg[2] E Fab MCAF5352A light chain[216 aa] A 100.0
/100.0
7
/7
IL17F_HUMAN Interleukin-17F
6wio[4] B Fab Light chain[213 aa] C 0.0
/61.4
2
/4
IL17_HUMAN Interleukin-17A
6wio[4] B Fab Light chain[213 aa] C 50.0
/61.4
4
/4
IL17_HUMAN Interleukin-17A
7z2m[4] C 11.003 Fab light-chain[213 aa] G 77.8
/59.2
9
/9
IL17_HUMAN Interleukin-17A
7z2m[4] L 11.003 Fab light-chain[213 aa] G 50.0
/59.2
2
/2
IL17_HUMAN Interleukin-17A
7z2m[4] D 11.003 Fab heavy-chain[220 aa] G 46.2
/59.2
13
/13
IL17_HUMAN Interleukin-17A
7z2m[1] D 11.003 Fab heavy-chain[220 aa] I 50.0
/56.6
2
/2
IL17_HUMAN Interleukin-17A
8b7w[2] A anti-IL-17A-76[125 aa] B 55.6
/60.4
18
/18
IL17_HUMAN Interleukin-17A
8b7w[2] A anti-IL-17A-76[125 aa] B 50.0
/60.4
2
/3
IL17_HUMAN Interleukin-17A
5n92[3] B IL17F_HUMAN Interleukin-17F[120 aa] A 65.2
/58.4
46
/54
IL17_HUMAN Interleukin-17A
7uwn[1] F I17RA_HUMAN Interleukin-17 receptor A[237 aa] D 75.0
/64.4
16
/19
IL17_HUMAN Interleukin-17A
7uwn[1] F I17RA_HUMAN Interleukin-17 receptor A[237 aa] E 50.0
/56.8
24
/24
IL17_HUMAN Interleukin-17A
3jvf[6] C I17RA_HUMAN Interleukin-17 receptor A[271 aa] A 100.0
/100.0
16
/16
IL17F_HUMAN Interleukin-17F
3jvf[6] C I17RA_HUMAN Interleukin-17 receptor A[271 aa] B 100.0
/100.0
25
/25
IL17F_HUMAN Interleukin-17F
4hsa[4] C I17RA_HUMAN Interleukin-17 receptor A[272 aa] A 78.9
/63.2
19
/20
IL17_HUMAN Interleukin-17A
4hsa[4] C I17RA_HUMAN Interleukin-17 receptor A[272 aa] B 47.8
/54.8
23
/23
IL17_HUMAN Interleukin-17A
6hg4[4] B I17RC_HUMAN Interleukin-17 receptor C[427 aa] A 100.0
/100.0
21
/21
IL17F_HUMAN Interleukin-17F
6hg4[4] B I17RC_HUMAN Interleukin-17 receptor C[427 aa] A 100.0
/100.0
16
/16
IL17F_HUMAN Interleukin-17F
7uwn[1] G I17RC_HUMAN Isoform 5 of Interleukin-17 receptor C[403 aa] A 46.7
/62.2
15
/19
IL17_HUMAN Interleukin-17A
7uwn[1] G I17RC_HUMAN Isoform 5 of Interleukin-17 receptor C[403 aa] B 71.4
/55.7
7
/9
IL17_HUMAN Interleukin-17A
7zan[2] D I17RC_HUMAN Isoform 2 of Interleukin-17 receptor C[422 aa] A 55.0
/57.3
20
/20
IL17_HUMAN Interleukin-17A
7zan[2] D I17RC_HUMAN Isoform 2 of Interleukin-17 receptor C[422 aa] B 71.4
/55.1
14
/15
IL17_HUMAN Interleukin-17A
7uwk[6] B I17RB_HUMAN Interleukin-17 receptor B[247 aa] A 43.8
/32.6
16
/16
IL25_HUMAN Interleukin-25
7uwk[6] D I17RB_HUMAN Interleukin-17 receptor B[235 aa] A 33.3
/32.6
12
/15
IL25_HUMAN Interleukin-25
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
COMPOUND
163 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
5hi3[2] H 63O
N-(4-{2-[({1-[2-(dimethylamino)-2-oxoethyl]cyclope..
A 80.0
/64.4
5
/5
IL17_HUMAN Interleukin-17A
5hi5[2] H 63Q
(4S,20R)-7-chloro-N-methyl-4-{[(1-methyl-1H-pyrazo..
A 75.0
/64.2
4
/4
IL17_HUMAN Interleukin-17A
8dyf[2] C U5I
(5M)-3-[({2-[2-(2-{2-[2-({[(5M)-3-carboxy-5-(5,8-d..
A 91.7
/62.4
12
/12
IL17_HUMAN Interleukin-17A
8cdg[2] C UTF
(9~{S},12~{R},19~{S})-9-[[4-[[(2~{S})-2-cyclohexyl..
A 44.4
/62.7
9
/9
IL17_HUMAN Interleukin-17A
8dyg[2] C U5Q
(5P)-2-hydroxy-5-(6-methylquinolin-5-yl)benzoic ac..
A 87.5
/64.7
8
/8
IL17_HUMAN Interleukin-17A
8dyg[2] D U5Q
(5P)-2-hydroxy-5-(6-methylquinolin-5-yl)benzoic ac..
A 100.0
/64.7
2
/2
IL17_HUMAN Interleukin-17A
8dyh[4] C U5X
(5P)-N-benzyl-6-chloro-5-(quinolin-5-yl)pyridin-3-..
A 100.0
/65.1
7
/7
IL17_HUMAN Interleukin-17A
1jpy[2] G NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..
A 100.0
/100.0
2
/2
interleukin 17F
5nan[4] L NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..
E 100.0
/100.0
1
/1
IL17F_HUMAN Interleukin-17F
6ppg[2] G NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..
A 100.0
/100.0
2
/2
IL17F_HUMAN Interleukin-17F
7uwn[1] I NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..
A 0.0
/62.2
2
/2
IL17_HUMAN Interleukin-17A
5hi4[2] H 63P
(9'S,17'R)-6'-chloro-N-methyl-9'-{[(1-methyl-1H-py..
A 54.5
/61.4
11
/11
IL17_HUMAN Interleukin-17A
7amg[4] E RMQ
(3~{R})-4-[4-[[(2~{S})-2-[[2,2-bis(fluoranyl)-2-ph..
A 58.3
/58.8
12
/12
IL17_HUMAN Interleukin-17A
7wkx[1] P MLA
MALONIC ACID[7 atoms]
E 0.0
/63.1
2
/2
IL17_HUMAN Interleukin-17A
7wkx[1] Q MLA
MALONIC ACID[7 atoms]
F 33.3
/61.4
3
/3
IL17_HUMAN Interleukin-17A
8dyi[4] C U6C
(5P)-5-[5-(benzylamino)pyridin-3-yl]-N-[2-(morphol..
A 83.3
/64.2
6
/6
IL17_HUMAN Interleukin-17A
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
METAL
163 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
3jvf[1] E CA
CALCIUM ION[1 atoms]
B 100.0
/100.0
2
/2
IL17F_HUMAN Interleukin-17F
6ppg[2] H CD
CADMIUM ION[1 atoms]
A 100.0
/100.0
2
/2
IL17F_HUMAN Interleukin-17F
6ppg[2] I CD
CADMIUM ION[1 atoms]
A 100.0
/100.0
1
/1
IL17F_HUMAN Interleukin-17F
6ppg[1] J CD
CADMIUM ION[1 atoms]
A 100.0
/100.0
1
/1
IL17F_HUMAN Interleukin-17F
6ppg[1] K CD
CADMIUM ION[1 atoms]
A 100.0
/100.0
1
/1
IL17F_HUMAN Interleukin-17F
6ppg[1] L CD
CADMIUM ION[1 atoms]
A 100.0
/100.0
1
/1
IL17F_HUMAN Interleukin-17F
6ppg[1] DB CD
CADMIUM ION[1 atoms]
F 100.0
/100.0
1
/1
IL17F_HUMAN Interleukin-17F
6ppg[1] HB CD
CADMIUM ION[1 atoms]
F 100.0
/100.0
1
/1
IL17F_HUMAN Interleukin-17F
6ppg[1] IB CD
CADMIUM ION[1 atoms]
F 100.0
/100.0
1
/1
IL17F_HUMAN Interleukin-17F
5vb9[2] G CL
CHLORIDE ION[1 atoms]
B 0.0
/62.7
1
/2
IL17_HUMAN Interleukin-17A
8dy5[1] G MG
MAGNESIUM ION[1 atoms]
D 100.0
/62.0
1
/1
IL17_HUMAN Interleukin-17A
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
OTHERPOLY
163 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1jpy[1] E 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-.. B 100.0
/100.0
2
/2
interleukin 17F
1jpy[1] F 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. C 100.0
/100.0
3
/3
interleukin 17F
3jvf[1] D 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. A 100.0
/100.0
3
/3
IL17F_HUMAN Interleukin-17F
6hgo[1] E 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. B 100.0
/100.0
3
/3
IL17F_HUMAN Interleukin-17F
5n92[1] C 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[al.. B 100.0
/100.0
3
/3
IL17F_HUMAN Interleukin-17F
5nan[1] G 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[be.. F 100.0
/100.0
2
/2
IL17F_HUMAN Interleukin-17F
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
HOMO
163 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1jpy[16] B interleukin 17F[121 aa] A 100.0
/100.0
64
/64
interleukin 17F
7uwn[1] E IL17_HUMAN Interleukin-17A[93 aa] D 80.0
/64.4
30
/41
IL17_HUMAN Interleukin-17A
2vxs[1] D IL17_HUMAN INTERLEUKIN-17A[77 aa] C 85.0
/63.2
20
/20
IL17_HUMAN INTERLEUKIN-17A
5hhx[2] B IL17_HUMAN Interleukin-17A[10 aa] A 0.0
/61.6
1
/1
IL17_HUMAN Interleukin-17A
2vxs[5] B IL17_HUMAN INTERLEUKIN-17A[80 aa] A 80.0
/64.2
20
/20
IL17_HUMAN INTERLEUKIN-17A
4hr9[59] B IL17_HUMAN Interleukin-17A[93 aa] A 79.3
/62.7
29
/41
IL17_HUMAN Interleukin-17A
5hhv[2] B IL17_HUMAN Interleukin-17A[10 aa] A 0.0
/60.0
1
/1
IL17_HUMAN Interleukin-17A
7uwk[6] C IL25_HUMAN Interleukin-25[100 aa] A 41.7
/32.6
12
/12
IL25_HUMAN Interleukin-25
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
PRECIPITANT
163 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1jpy[1] H SO4
SULFATE ION[5 atoms]
C 100.0
/100.0
2
/2
interleukin 17F
2vxs[4] M SO4
SULFATE ION[5 atoms]
A 40.0
/64.2
5
/5
IL17_HUMAN INTERLEUKIN-17A
2vxs[1] O SO4
SULFATE ION[5 atoms]
B 50.0
/63.2
2
/2
IL17_HUMAN INTERLEUKIN-17A
4qhu[2] O SO4
SULFATE ION[5 atoms]
E 40.0
/56.2
5
/5
IL17_HUMAN Interleukin-17A
4qhu[1] P SO4
SULFATE ION[5 atoms]
E 0.0
/56.2
5
/5
IL17_HUMAN Interleukin-17A
6hgo[1] I SO4
SULFATE ION[5 atoms]
D 100.0
/100.0
3
/3
IL17F_HUMAN Interleukin-17F
8b7w[4] E SO4
SULFATE ION[5 atoms]
B 100.0
/60.4
2
/2
IL17_HUMAN Interleukin-17A
7wkx[1] J ACY
ACETIC ACID[4 atoms]
E 66.7
/63.1
3
/3
IL17_HUMAN Interleukin-17A
4qhu[1] L GOL
GLYCEROL[6 atoms]
F 0.0
/62.5
3
/3
IL17_HUMAN Interleukin-17A
7z2m[3] N GOL
GLYCEROL[6 atoms]
G 0.0
/59.2
1
/1
IL17_HUMAN Interleukin-17A
8dyh[1] D GOL
GLYCEROL[6 atoms]
A 100.0
/65.1
2
/2
IL17_HUMAN Interleukin-17A
8dyh[1] D GOL
GLYCEROL[6 atoms]
B 66.7
/62.8
3
/3
IL17_HUMAN Interleukin-17A
5vb9[4] E EDO
1,2-ETHANEDIOL[4 atoms]
A 75.0
/63.2
4
/4
IL17_HUMAN Interleukin-17A
5vb9[2] F EDO
1,2-ETHANEDIOL[4 atoms]
A 100.0
/63.2
5
/5
IL17_HUMAN Interleukin-17A
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.