Contact Molecules for Homologous Proteins | ||||
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PID | QueryLength | Homolgous Sequence in PDB | UniProt Query | TITLE |
3960881 | 557 | 46 | P17181(INAR1_HUMAN) | RecName: Full=Interferon alpha/beta receptor 1; Short=IFN-R-1; Short=IFN-alpha/beta receptor 1;AltName: Full=Cytokine receptor class-II member 1;AltName: Full=Cytokine receptor family 2 member 1; Short=CRF2-1;AltName: Full=Type I interferon receptor 1;Flags: Precursor; |
QUERYSEQ |
MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVTFSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAIVIHISPGT KDSVMWALDGLSFTYSLVIWKNSSGVEERIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQK GIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAPKQSGNTPVIQDYPLIYEIIFWENTSNAERKIIEKKTDVTVPNLKPLTVYCVKARAHTMDEKLNKSSVFSDAVCEKTKPGNTSKIWLIVGICIALFAL PFVIYAAKVFLRCINYVFFPSLKPSSSIDEYFSEQPLKNLLLSTSEEQIEKCFIIENISTIATVEETNQTDEDHKKYSSQTSQDSGNYSNEDESESKTSEELQQDFV |
557 | region | name | description |
1-27 | SIGNAL | ||
28-557 | CHAIN | /note="Interferon alpha/beta receptor 1" /id="PRO_0000011001" | |
28-436 | TOPO_DOM | /note="Extracellular" | |
437-457 | TRANSMEM | /note="Helical" | |
458-557 | TOPO_DOM | /note="Cytoplasmic" | |
32-126 | DOMAIN | /note="Fibronectin type-III 1" | |
127-227 | DOMAIN | /note="Fibronectin type-III 2" | |
231-329 | DOMAIN | /note="Fibronectin type-III 3" | |
331-432 | DOMAIN | /note="Fibronectin type-III 4" | |
491-500 | REGION | /note="Important for interaction with TYK2" | |
516-557 | REGION | /note="Disordered" | |
540-557 | COMPBIAS | /note="Basic and acidic residues" | |
463-463 | LIPID | /note="S-palmitoyl cysteine" | |
1-557 | DISORDER | predicted by DISOPRED |
MONOMER | |||||||
557 | |||||||
pdb_id | a1 | identity[%]2 | description | ||||
3se3 | A | 100.0 | INAR1_HUMAN Interferon alpha/beta receptor 1 | ||||
3wcy | A | 48.9 | INAR1_MOUSE Interferon alpha/beta receptor 1 | ||||
4po6 | B | 100.0 | INAR1_HUMAN Interferon alpha/beta receptor 1 | ||||
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue. |
HETERO | |||||||
557 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
3se3[1] | B | Q86UP4_HUMAN Interferon alpha 2b[128 aa] | A | 100.0 /100.0 |
17 /17 |
INAR1_HUMAN Interferon alpha/beta receptor 1 | |
3se4[1] | B | IFNW1_HUMAN Interferon omega-1[143 aa] | A | 100.0 /100.0 |
20 /20 |
INAR1_HUMAN Interferon alpha/beta receptor 1 | |
4po6[1] | A | TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2[475 aa] | B | 100.0 /100.0 |
16 /16 |
INAR1_HUMAN Interferon alpha/beta receptor 1 | |
3wcy[1] | B | IFNB_MOUSE Interferon beta[160 aa] | A | 25.0 /48.9 |
32 /32 |
INAR1_MOUSE Interferon alpha/beta receptor 1 | |
6x93[1] | A | IL10_HUMAN Interleukin-10[135 aa] | C | 18.8 /31.6 |
16 /18 |
I10R2_HUMAN Interleukin-10 receptor subunit beta | |
6x93[1] | B | I10R1_HUMAN Interleukin-10 receptor subunit alpha[198 aa] | C | 25.0 /31.6 |
4 /4 |
I10R2_HUMAN Interleukin-10 receptor subunit beta | |
6x93[1] | D | IL10_HUMAN Interleukin-10[145 aa] | F | 0.0 /31.6 |
4 /5 |
I10R2_HUMAN Interleukin-10 receptor subunit beta | |
4doh[2] | A | IL20_HUMAN Interleukin-20[153 aa] | C | 20.0 /31.3 |
15 /18 |
I20RA_HUMAN Interleukin-20 receptor subunit alpha | |
5t5w[1] | B | INLR1_HUMAN Interferon lambda receptor 1[188 aa] | A | 18.2 /30.8 |
11 /13 |
I10R2_HUMAN Interleukin-10 receptor subunit beta | |
5t5w[1] | C | IFNL3_HUMAN Interferon lambda-3[151 aa] | A | 16.7 /30.8 |
12 /13 |
I10R2_HUMAN Interleukin-10 receptor subunit beta | |
6df3[1] | B | IL24_HUMAN Interleukin-24[155 aa] | A | 18.2 /26.1 |
11 /14 |
I22R1_HUMAN Interleukin-22 receptor subunit alpha-1 | |
6df3[1] | B | IL24_HUMAN Interleukin-24[155 aa] | C | 16.7 /29.3 |
18 /19 |
I20RB_HUMAN Interleukin-20 receptor subunit beta | |
6df3[1] | A | I22R1_HUMAN Interleukin-22 receptor subunit alpha-1[199 aa] | C | 50.0 /29.3 |
6 /8 |
I20RB_HUMAN Interleukin-20 receptor subunit beta | |
6weo[12] | IA | I22R1_MOUSE Interleukin-22 receptor subunit alpha-1[201 aa] | A | 33.3 /29.2 |
6 /6 |
I10R2_MOUSE Interleukin-10 receptor subunit beta | |
6e3k[4] | B | IFNG_HUMAN Interferon gamma[126 aa] | E | 15.4 /27.2 |
13 /14 |
INGR2_HUMAN Interferon gamma receptor 2 | |
6e3k[4] | D | INGR1_HUMAN Interferon gamma receptor 1[203 aa] | E | 5.6 /27.2 |
18 /19 |
INGR2_HUMAN Interferon gamma receptor 2 | |
3dgc[3] | A | IL22_HUMAN Interleukin-22[141 aa] | B | 23.1 /24.2 |
13 /16 |
I22R1_HUMAN Interleukin-22 receptor subunit alpha-1 | |
3dgc[2] | C | IL22_HUMAN Interleukin-22[141 aa] | B | 12.5 /24.2 |
8 /12 |
I22R1_HUMAN Interleukin-22 receptor subunit alpha-1 | |
6df3[1] | C | I20RB_HUMAN Interleukin-20 receptor subunit beta[190 aa] | A | 25.0 /26.1 |
8 /8 |
I22R1_HUMAN Interleukin-22 receptor subunit alpha-1 | |
6weo[12] | JA | IL22_MOUSE Interleukin-22[141 aa] | A | 20.0 /29.2 |
15 /17 |
I10R2_MOUSE Interleukin-10 receptor subunit beta | |
6weo[12] | C | IL22_MOUSE Interleukin-22[140 aa] | B | 40.0 /22.1 |
10 /13 |
I22R1_MOUSE Interleukin-22 receptor subunit alpha-1 | |
6weo[12] | D | I10R2_MOUSE Interleukin-10 receptor subunit beta[195 aa] | B | 66.7 /22.1 |
3 /7 |
I22R1_MOUSE Interleukin-22 receptor subunit alpha-1 | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
COMPOUND | |||||||
557 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
5eh1[5] | B |
CYS
CYSTEINE[7 atoms] |
A | 0.0 /27.2 |
3 /3 |
INGR2_HUMAN Interferon gamma receptor 2 | |
3s98[2] | B |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
A | 100.0 /100.0 |
3 /3 |
IFNAR1_HUMAN Interferon alpha/beta receptor 1 | |
3se3[2] | D |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
A | 100.0 /100.0 |
1 /1 |
INAR1_HUMAN Interferon alpha/beta receptor 1 | |
4doh[1] | H |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
C | 0.0 /31.3 |
2 /2 |
I20RA_HUMAN Interleukin-20 receptor subunit alpha | |
5eh1[5] | C |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
A | 40.0 /27.2 |
5 /5 |
INGR2_HUMAN Interferon gamma receptor 2 | |
5eh1[3] | E |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
A | 0.0 /27.2 |
2 /2 |
INGR2_HUMAN Interferon gamma receptor 2 | |
6df3[1] | E |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
A | 50.0 /26.1 |
4 /4 |
I22R1_HUMAN Interleukin-22 receptor subunit alpha-1 | |
6e3k[2] | U |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
E | 0.0 /27.2 |
1 /1 |
INGR2_HUMAN Interferon gamma receptor 2 | |
6e3l[1] | R |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
E | 100.0 /27.2 |
2 /4 |
INGR2_HUMAN Interferon gamma receptor 2 | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
METAL | |||||||
557 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
3dgc[2] | H |
CL
CHLORIDE ION[1 atoms] |
B | 20.0 /24.2 |
5 /6 |
I22R1_HUMAN Interleukin-22 receptor subunit alpha-1 | |
3dgc[1] | S |
CL
CHLORIDE ION[1 atoms] |
D | 33.3 /24.2 |
3 /3 |
I22R1_HUMAN Interleukin-22 receptor subunit alpha-1 | |
3dgc[2] | I |
U1
URANIUM ATOM[1 atoms] |
B | 0.0 /24.2 |
1 /1 |
I22R1_HUMAN Interleukin-22 receptor subunit alpha-1 | |
3dgc[1] | J |
U1
URANIUM ATOM[1 atoms] |
B | 0.0 /24.2 |
1 /2 |
I22R1_HUMAN Interleukin-22 receptor subunit alpha-1 | |
3dgc[2] | K |
U1
URANIUM ATOM[1 atoms] |
B | 33.3 /24.2 |
3 /3 |
I22R1_HUMAN Interleukin-22 receptor subunit alpha-1 | |
3dgc[1] | L |
U1
URANIUM ATOM[1 atoms] |
B | 100.0 /24.2 |
1 /2 |
I22R1_HUMAN Interleukin-22 receptor subunit alpha-1 | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
OTHERPOLY | |||||||
557 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
6df3[1] | D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | A | 20.0 /26.1 |
5 /6 |
I22R1_HUMAN Interleukin-22 receptor subunit alpha-1 | |
6e3k[3] | G | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | E | 20.0 /27.2 |
5 /5 |
INGR2_HUMAN Interferon gamma receptor 2 | |
6weo[1] | AB | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | BA | 0.0 /29.2 |
1 /1 |
I10R2_MOUSE Interleukin-10 receptor subunit beta | |
6e3l[2] | I | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. | E | 25.0 /27.2 |
4 /4 |
INGR2_HUMAN Interferon gamma receptor 2 | |
6weo[1] | QA | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. | K | 25.0 /22.1 |
4 /4 |
I22R1_MOUSE Interleukin-22 receptor subunit alpha-1 | |
6weo[1] | QA | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. | M | 100.0 /29.2 |
1 /1 |
I10R2_MOUSE Interleukin-10 receptor subunit beta | |
6weo[1] | GB | alpha-L-fucopyranose-(1-3)-[alpha-L-fucopyranose-(.. | A | 50.0 /29.2 |
2 /2 |
I10R2_MOUSE Interleukin-10 receptor subunit beta | |
6weo[4] | CB | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[al.. | EA | 0.0 /29.2 |
2 /2 |
I10R2_MOUSE Interleukin-10 receptor subunit beta | |
6weo[2] | OA | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[al.. | H | 25.0 /22.1 |
4 /7 |
I22R1_MOUSE Interleukin-22 receptor subunit alpha-1 | |
6weo[1] | OA | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[al.. | J | 0.0 /29.8 |
1 /1 |
I10R2_MOUSE Interleukin-10 receptor subunit beta | |
6weo[1] | RA | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. | O | 0.0 /29.2 |
2 /2 |
I10R2_MOUSE Interleukin-10 receptor subunit beta | |
6weo[1] | UA | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. | S | 25.0 /22.1 |
4 /8 |
I22R1_MOUSE Interleukin-22 receptor subunit alpha-1 | |
6weo[1] | UA | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. | U | 100.0 /29.2 |
1 /1 |
I10R2_MOUSE Interleukin-10 receptor subunit beta | |
6e3k[1] | H | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose.. | F | 20.0 /27.2 |
5 /5 |
INGR2_HUMAN Interferon gamma receptor 2 | |
6e3l[1] | L | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-.. | F | 20.0 /27.2 |
5 /5 |
INGR2_HUMAN Interferon gamma receptor 2 | |
3dgc[1] | E | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(.. | B | 28.6 /24.2 |
7 /7 |
I22R1_HUMAN Interleukin-22 receptor subunit alpha-1 | |
6weo[3] | KA | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. | B | 25.0 /22.1 |
4 /8 |
I22R1_MOUSE Interleukin-22 receptor subunit alpha-1 | |
6weo[4] | BB | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-bet.. | CA | 25.0 /22.1 |
4 /8 |
I22R1_MOUSE Interleukin-22 receptor subunit alpha-1 | |
6weo[3] | NA | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-bet.. | G | 50.0 /29.2 |
2 /2 |
I10R2_MOUSE Interleukin-10 receptor subunit beta | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
PRECIPITANT | |||||||
557 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
3lqm[2] | C |
SO4
SULFATE ION[5 atoms] |
A | 40.0 /30.4 |
5 /5 |
I10R2_HUMAN Interleukin-10 receptor subunit beta | |
3lqm[2] | D |
SO4
SULFATE ION[5 atoms] |
A | 50.0 /30.4 |
4 /4 |
I10R2_HUMAN Interleukin-10 receptor subunit beta | |
3lqm[2] | E |
SO4
SULFATE ION[5 atoms] |
A | 50.0 /30.4 |
2 /2 |
I10R2_HUMAN Interleukin-10 receptor subunit beta | |
3lqm[1] | G |
SO4
SULFATE ION[5 atoms] |
B | 50.0 /30.8 |
4 /6 |
I10R2_HUMAN Interleukin-10 receptor subunit beta | |
3lqm[1] | H |
SO4
SULFATE ION[5 atoms] |
B | 33.3 /30.8 |
3 /3 |
I10R2_HUMAN Interleukin-10 receptor subunit beta | |
3lqm[1] | L |
SO4
SULFATE ION[5 atoms] |
B | 0.0 /30.8 |
2 /2 |
I10R2_HUMAN Interleukin-10 receptor subunit beta | |
3lqm[1] | M |
SO4
SULFATE ION[5 atoms] |
B | 100.0 /30.8 |
2 /2 |
I10R2_HUMAN Interleukin-10 receptor subunit beta | |
3lqm[1] | F |
GOL
GLYCEROL[6 atoms] |
A | 20.0 /30.4 |
5 /5 |
I10R2_HUMAN Interleukin-10 receptor subunit beta | |
5eh1[1] | F |
GOL
GLYCEROL[6 atoms] |
A | 0.0 /27.2 |
4 /4 |
INGR2_HUMAN Interferon gamma receptor 2 | |
5eh1[1] | G |
GOL
GLYCEROL[6 atoms] |
A | 42.9 /27.2 |
7 /9 |
INGR2_HUMAN Interferon gamma receptor 2 | |
5eh1[1] | H |
GOL
GLYCEROL[6 atoms] |
A | 40.0 /27.2 |
5 /5 |
INGR2_HUMAN Interferon gamma receptor 2 | |
6df3[1] | F |
GOL
GLYCEROL[6 atoms] |
A | 0.0 /26.1 |
2 /2 |
I22R1_HUMAN Interleukin-22 receptor subunit alpha-1 | |
6weo[1] | JB |
GOL
GLYCEROL[6 atoms] |
R | 0.0 /29.2 |
2 /2 |
I10R2_MOUSE Interleukin-10 receptor subunit beta | |
6weo[2] | LB |
GOL
GLYCEROL[6 atoms] |
U | 0.0 /29.2 |
2 /3 |
I10R2_MOUSE Interleukin-10 receptor subunit beta | |
6weo[1] | MB |
GOL
GLYCEROL[6 atoms] |
W | 0.0 /22.1 |
4 /7 |
I22R1_MOUSE Interleukin-22 receptor subunit alpha-1 | |
6e3k[1] | AA |
EDO
1,2-ETHANEDIOL[4 atoms] |
F | 100.0 /27.2 |
1 /2 |
INGR2_HUMAN Interferon gamma receptor 2 | |
6e3k[1] | BA |
EDO
1,2-ETHANEDIOL[4 atoms] |
F | 100.0 /27.2 |
2 /3 |
INGR2_HUMAN Interferon gamma receptor 2 | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. |