Contact Molecules for Homologous Proteins

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PID QueryLength Homolgous Sequence in PDB UniProt Query TITLE
1223578 605 12 Q16236(NF2L2_HUMAN) RecName: Full=Nuclear factor erythroid 2-related factor 2 ; Short=NF-E2-related factor 2 ; Short=NFE2-related factor 2 ; Short=Nrf-2 ;AltName: Full=Nuclear factor, erythroid derived 2, like 2 ;
QUERYSEQ 
MMDLELPPPGLPSQQDMDLIDILWRQDIDLGVSREVFDFSQRRKEYELEKQKKLEKERQEQLQKEQEKAFFAQLQLDEETGEFLPIQPAQHIQSETSGSANYSQVAHIPKSDALYFDDCMQLLAQTFPFVDDNEVSSATFQSLVPDIPGH
IESPVFIATNQAQSPETSVAQVAPVDLDGMQQDIEQVWEELLSIPELQCLNIENDKLVETTMVPSPEAKLTEVDNYHFYSSIPSMEKEVGNCSPHFLNAFEDSFSSILSTEDPNQLTVNSLNSDATVNTDFGDEFYSAFIAEPSISNSMP
SPATLSHSLSELLNGPIDVSDLSLCKAFNQNHPESTAEFNDSDSGISLNTSPSVASPEHSVESSSYGDTLLGLSDSEVEELDSAPGSVKQNGPKTPVHSSGDMVQPLSPSQGQSTHVHDAQCENTPEKELPVSPGHRKTPFTKDKHSSRL
EAHLTRDELRAKALHIPFPVEKIINLPVVDFNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLDHLKDEKEKLLKEKGENDKSLHLLKKQLSTLYLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKSKKP
DVKKN
[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]

UniProt Feature Tables [Q16236(NF2L2_HUMAN)]

605
region name description
1-605 CHAIN /note="Nuclear factor erythroid 2-related factor 2" /id="PRO_0000076449"
497-560 DOMAIN /note="bZIP"
334-449 REGION /note="Disordered"
499-518 REGION /note="Basic motif"
522-529 REGION /note="Leucine-zipper"
571-605 REGION /note="Disordered"
591-596 REGION /note="Mediates interaction with CHD6 and is necessary to activate transcription"
334-371 COMPBIAS /note="Polar residues"
388-420 COMPBIAS /note="Polar residues"
421-449 COMPBIAS /note="Basic and acidic residues"
1-605 DISORDER predicted by DISOPRED

MONOMER
605
pdb_id a1 identity[%]2 description
7x5e B 100.0 NF2L2_HUMAN Nuclear factor erythroid 2-related factor 2
3wn7 D 100.0 NF2L2_MOUSE Peptide from Nuclear factor erythroid 2-related factor 2 
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue.
HETERO
605 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
3wn7[2] A KEAP1_MOUSE Kelch-like ECH-associated protein 1[286 aa] B 100.0
/100.0		 14
/14		 NF2L2_MOUSE Peptide from Nuclear factor erythroid 2-related fa..
7x5e[6] A MAFG_HUMAN Transcription factor MafG[99 aa] B 100.0
/100.0		 18
/18		 NF2L2_HUMAN Nuclear factor erythroid 2-related factor 2
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
NUCLEOTIDE
605 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
7x5e[2] C DNA (5'-D(*GP*TP*TP*GP*CP*TP*GP*AP*CP*TP*CP*AP*TP*.. B 100.0
/100.0		 6
/6		 NF2L2_HUMAN Nuclear factor erythroid 2-related factor 2
7x5e[2] D DNA (5'-D(*CP*AP*TP*GP*AP*TP*GP*AP*GP*TP*CP*AP*GP*.. B 100.0
/100.0		 10
/10		 NF2L2_HUMAN Nuclear factor erythroid 2-related factor 2
7x5f[4] C Synthetic DNA B 100.0
/100.0		 7
/7		 NF2L2_HUMAN Nuclear factor erythroid 2-related factor 2
7x5f[4] D Synthetic DNA B 100.0
/100.0		 11
/11		 NF2L2_HUMAN Nuclear factor erythroid 2-related factor 2
1skn[1] A DNA (5'-D(*TP*GP*AP*CP*AP*AP*TP*GP*TP*CP*AP*TP*CP*.. C 75.0
/39.1		 8
/8		 SKN1_CAEEL DNA-BINDING DOMAIN OF SKN-1
1skn[1] B DNA (5'-D(*CP*AP*GP*GP*GP*AP*TP*GP*AP*CP*AP*TP*TP*.. C 87.5
/39.1		 8
/9		 SKN1_CAEEL DNA-BINDING DOMAIN OF SKN-1
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
PRECIPITANT
605 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
7x5e[1] I P6G
HEXAETHYLENE GLYCOL[19 atoms] 		F 100.0
/100.0		 2
/2		 NF2L2_HUMAN Nuclear factor erythroid 2-related factor 2
1skn[1] D LDA
LAURYL DIMETHYLAMINE-N-OXIDE[16 atoms] 		C 50.0
/39.1		 4
/4		 SKN1_CAEEL DNA-BINDING DOMAIN OF SKN-1
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.