HOMCOS(prot_sch_conbars.cgi):

		Contact Molecules for Homologous Proteins
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PID

QueryLength

Homolgous Sequence in PDB

UniProt Query

TITLE

2684896

1041

145

Q9NR97(TLR8_HUMAN)

RecName: Full=Toll-like receptor 8 ;AltName: CD_antigen=CD288;Flags: Precursor;

QUERYSEQ

MENMFLQSSMLTCIFLLISGSCELCAEENFSRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTE
LSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLR
KINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKDTRQSYANSSSFQRH
IRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLT
DKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKT
INKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTCVSDVTAVILFFFTFFITTMVMLAALAHHLFYWDVWFIYNVCLAKVKGYRSLSTSQTFYDAYISYDTKDASVTDWVINE
LRYHLEESRDKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTVFVLTKKYAKSWNFKTAFYLALQRLMDENMDVIIFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFWQTLRNVVLTENDSRYNNMYVDSIKQY

[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]

UniProt Feature Tables [Q9NR97(TLR8_HUMAN)]

1041
	region	name	description
	1-26	SIGNAL
	27-1041	CHAIN	/note="Toll-like receptor 8" /id="PRO_0000034735"
	27-827	TOPO_DOM	/note="Extracellular"
	828-848	TRANSMEM	/note="Helical"
	849-1041	TOPO_DOM	/note="Cytoplasmic"
	126-147	REPEAT	/note="LRR 1"
	148-168	REPEAT	/note="LRR 2"
	171-193	REPEAT	/note="LRR 3"
	202-223	REPEAT	/note="LRR 4"
	224-244	REPEAT	/note="LRR 5"
	247-268	REPEAT	/note="LRR 6"
	288-309	REPEAT	/note="LRR 7"
	312-334	REPEAT	/note="LRR 8"
	338-360	REPEAT	/note="LRR 9"
	368-389	REPEAT	/note="LRR 10"
	395-416	REPEAT	/note="LRR 11"
	419-440	REPEAT	/note="LRR 12"
	482-503	REPEAT	/note="LRR 13"
	506-527	REPEAT	/note="LRR 14"
	531-551	REPEAT	/note="LRR 15"
	555-577	REPEAT	/note="LRR 16"
	585-606	REPEAT	/note="LRR 17"
	609-630	REPEAT	/note="LRR 18"
	640-661	REPEAT	/note="LRR 19"
	665-685	REPEAT	/note="LRR 20"
	689-710	REPEAT	/note="LRR 21"
	713-734	REPEAT	/note="LRR 22"
	737-758	REPEAT	/note="LRR 23"
	772-824	DOMAIN	/note="LRRCT"
	878-1022	DOMAIN	/note="TIR"
	1-1041	DISORDER	predicted by DISOPRED

MONOMER

1041

pdb_id a¹ identity[%]² description

4qbz A 100.0 TLR8_HUMAN Toll-like receptor 8

7cyn B 43.2 TLR7_HUMAN Toll-like receptor 7

1fyw A 43.0 TLR2_HUMAN TOLL-LIKE RECEPTOR 2

1.a¹:asym_id for the homologue. 2.identity[%]²:sequence identity between the query and the homologue.

HETERO

1041 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

7cyn[2] C UN93B_HUMAN Protein unc-93 homolog B1[483 aa] A 50.0
/43.2 18
/18 TLR7_HUMAN Toll-like receptor 7

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

NUCLEOTIDE

1041 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

5gmf[6] G RNA (5'-R(P*UP*UP*UP*U)-3') A 0.0
/43.1 1
/1 B3Y653_MACMU Toll-like receptor 7

5gmf[6] H RNA (5'-R(P*UP*UP*UP*U)-3') A 9.1
/43.1 22
/22 B3Y653_MACMU Toll-like receptor 7

5zsa[2] C RNA (5'-R(P*UP*UP*UP*U)-3') A 9.1
/43.1 22
/22 B3Y653_MACMU Toll-like receptor 7

5zsa[2] D RNA (5'-R(P*UP*UP*UP*U)-3') A 0.0
/43.1 1
/1 B3Y653_MACMU Toll-like receptor 7

5zsb[1] C RNA (5'-R(*AP*UP*UP*AP*A)-3') A 33.3
/43.1 3
/3 B3Y653_MACMU Toll-like receptor 7

5zsb[1] C RNA (5'-R(*AP*UP*UP*AP*A)-3') B 10.5
/43.2 19
/21 B3Y653_MACMU Toll-like receptor 7

5zsb[3] D RNA (5'-R(*AP*UP*UP*AP*A)-3') A 9.5
/43.1 21
/21 B3Y653_MACMU Toll-like receptor 7

5zsb[2] D RNA (5'-R(*AP*UP*UP*AP*A)-3') B 0.0
/43.2 1
/1 B3Y653_MACMU Toll-like receptor 7

5zsd[2] C RNA (5'-R(P*UP*UP*GP*A)-3') A 0.0
/43.1 1
/1 B3Y653_MACMU Toll-like receptor 7

5zsd[4] D RNA (5'-R(P*UP*UP*GP*A)-3') A 9.5
/43.1 21
/21 B3Y653_MACMU Toll-like receptor 7

5zse[4] C RNA (5'-R(*GP*UP*CP*CP*C)-3') A 25.0
/43.1 4
/4 B3Y653_MACMU Toll-like receptor 7

5zse[4] D RNA (5'-R(*GP*UP*CP*CP*C)-3') A 9.5
/43.1 21
/22 B3Y653_MACMU Toll-like receptor 7

5zsc[2] C RNA (5'-R(P*UP*UP*CP*A)-3') A 50.0
/43.1 2
/2 B3Y653_MACMU Toll-like receptor 7

5zsc[2] D RNA (5'-R(P*UP*UP*CP*A)-3') A 9.1
/43.1 22
/22 B3Y653_MACMU Toll-like receptor 7

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

COMPOUND

1041 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

3wn4[2] E D87
2-butylfuro[2,3-c]quinolin-4-amine[18 atoms] A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

4qbz[2] O D80
2-butyl[1,3]oxazolo[4,5-c]quinolin-4-amine[18 atom.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

4qbz[2] P D80
2-butyl[1,3]oxazolo[4,5-c]quinolin-4-amine[18 atom.. A 100.0
/100.0 8
/8 TLR8_HUMAN Toll-like receptor 8

4qc0[2] J XG1
2-butyl-2H-pyrazolo[3,4-c]quinolin-4-amine[18 atom.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

4qc0[2] K XG1
2-butyl-2H-pyrazolo[3,4-c]quinolin-4-amine[18 atom.. A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

4r07[14] Q URI
URIDINE[17 atoms] A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

4r07[14] X URI
URIDINE[17 atoms] A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

4r07[8] R UCG
3'-O-[(R)-{[(2R,3aR,4R,6R,6aR)-6-(2-amino-6-oxo-1,.. A 100.0
/100.0 15
/15 TLR8_HUMAN Toll-like receptor 8

4r09[4] Q 06S
O-[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3,6-dihydro-9H-p.. A 100.0
/100.0 15
/15 TLR8_HUMAN Toll-like receptor 8

4r09[4] R UPT
1-[(2R,3aR,4R,6R,6aR)-2-hydroxy-6-(hydroxymethyl)-.. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

4r09[4] V UPT
1-[(2R,3aR,4R,6R,6aR)-2-hydroxy-6-(hydroxymethyl)-.. A 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

4r6a[2] M HB2
1-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl).. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

4r6a[2] N HB2
1-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl).. A 100.0
/100.0 11
/11 TLR8_HUMAN Toll-like receptor 8

5awa[2] E M8D
5-[[3-(aminomethyl)phenyl]methyl]-3-pentyl-quinoli.. A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

5awa[2] E M8D
5-[[3-(aminomethyl)phenyl]methyl]-3-pentyl-quinoli.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

5awb[2] E M0A
1-[[3-(aminomethyl)phenyl]methyl]-2-butyl-imidazo[.. A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

5awb[2] E M0A
1-[[3-(aminomethyl)phenyl]methyl]-2-butyl-imidazo[.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

5awc[4] T M4D
5-(4-azanylbutyl)-3-pentyl-quinolin-2-amine[21 ato.. A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

5awc[4] U M4D
5-(4-azanylbutyl)-3-pentyl-quinolin-2-amine[21 ato.. A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

5az5[4] Q MBL
1-pentyl-4-phenyl-imidazol-2-amine[17 atoms] A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

5az5[4] U MBL
1-pentyl-4-phenyl-imidazol-2-amine[17 atoms] A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

5wyx[2] M CU8
7-(3-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carb.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

5wyx[2] N CU8
7-(3-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carb.. A 100.0
/100.0 11
/11 TLR8_HUMAN Toll-like receptor 8

5wyz[2] I 7VF
4-(3-methyl-4-oxidanyl-phenyl)quinolin-7-ol[19 ato.. A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

5wyz[2] M 7VF
4-(3-methyl-4-oxidanyl-phenyl)quinolin-7-ol[19 ato.. A 100.0
/100.0 11
/11 TLR8_HUMAN Toll-like receptor 8

5z14[2] I 7VC
4-(7-methoxyquinolin-4-yl)-2-methyl-phenol[20 atom.. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

5z14[2] L 7VC
4-(7-methoxyquinolin-4-yl)-2-methyl-phenol[20 atom.. A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

5z15[2] I 7VL
4-(7-chloranylquinolin-4-yl)-2-methyl-phenol[19 at.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

5z15[2] N 7VL
4-(7-chloranylquinolin-4-yl)-2-methyl-phenol[19 at.. A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

6kya[2] I DY3
3-[5-methylsulfanyl-4-(3,4,5-trimethylphenyl)-1,2,.. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

6kya[2] N DY3
3-[5-methylsulfanyl-4-(3,4,5-trimethylphenyl)-1,2,.. A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

6ty5[1] O O0W
5-methyl-7-(7-methyl-2-piperidin-4-yl-indazol-5-yl.. B 100.0
/100.0 11
/11 TLR8_HUMAN Toll-like receptor 8

6ty5[1] V O0W
5-methyl-7-(7-methyl-2-piperidin-4-yl-indazol-5-yl.. B 100.0
/100.0 8
/8 TLR8_HUMAN Toll-like receptor 8

6v9u[2] AA QSM
2-(3,4-dimethoxyphenyl)-5-(piperidin-4-yl)-3-(prop.. A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

6v9u[2] R QSM
2-(3,4-dimethoxyphenyl)-5-(piperidin-4-yl)-3-(prop.. A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

6wml[4] GA U57
(2R)-2-[(2-amino-7-fluoropyrido[3,2-d]pyrimidin-4-.. A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

6wml[4] X U57
(2R)-2-[(2-amino-7-fluoropyrido[3,2-d]pyrimidin-4-.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

6wml[2] Q MAN
alpha-D-mannopyranose[11 atoms] A 100.0
/100.0 2
/2 TLR8_HUMAN Toll-like receptor 8

6zjz[2] N QLH
5-[(3~{R},5~{S})-3-azanyl-5-(trifluoromethyl)piper.. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

6zjz[2] S QLH
5-[(3~{R},5~{S})-3-azanyl-5-(trifluoromethyl)piper.. A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

7crf[2] I GD0
1-[2-(ethoxymethyl)-4-iodanyl-5-phenyl-imidazol-1-.. A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

7crf[2] U GD0
1-[2-(ethoxymethyl)-4-iodanyl-5-phenyl-imidazol-1-.. A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

7r52[2] O I6A
5-methoxy-6-pyridin-4-yl-1~{H}-indole[17 atoms] A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

7r52[2] V I6A
5-methoxy-6-pyridin-4-yl-1~{H}-indole[17 atoms] A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

7r53[2] O I5N
5-cyclopropyl-6-(2,6-dimethylpyridin-4-yl)-~{N}-[(.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

7r53[2] P I5N
5-cyclopropyl-6-(2,6-dimethylpyridin-4-yl)-~{N}-[(.. A 100.0
/100.0 12
/12 TLR8_HUMAN Toll-like receptor 8

7r54[2] O I5B
(5-methoxy-6-pyridin-4-yl-1~{H}-indazol-3-yl)-(4-m.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

7r54[2] P I5B
(5-methoxy-6-pyridin-4-yl-1~{H}-indazol-3-yl)-(4-m.. A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

7rc9[2] P RQY
2-(2,6-dimethylpyridin-4-yl)-5-(piperidin-4-yl)-3-.. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

7rc9[2] X RQY
2-(2,6-dimethylpyridin-4-yl)-5-(piperidin-4-yl)-3-.. A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

7ytp[2] N JRI
(2R,6R)-4-(8-cyanoquinolin-5-yl)-N-[(3S,4R)-4-fluo.. A 25.0
/44.2 8
/8 B3Y653_MACMU Toll-like receptor 7

7ytp[2] T JRI
(2R,6R)-4-(8-cyanoquinolin-5-yl)-N-[(3S,4R)-4-fluo.. A 50.0
/44.2 4
/4 B3Y653_MACMU Toll-like receptor 7

7ytx[2] I JRI
(2R,6R)-4-(8-cyanoquinolin-5-yl)-N-[(3S,4R)-4-fluo.. A 100.0
/100.0 12
/12 TLR8_HUMAN Toll-like receptor 8

7ytx[2] S JRI
(2R,6R)-4-(8-cyanoquinolin-5-yl)-N-[(3S,4R)-4-fluo.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

8pfi[2] O YHG
(3~{S})-~{N}-[4-[[5-(1,6-dimethylpyrazolo[3,4-b]py.. A 100.0
/100.0 13
/13 TLR8_HUMAN Toll-like receptor 8

8pfi[2] P YHG
(3~{S})-~{N}-[4-[[5-(1,6-dimethylpyrazolo[3,4-b]py.. A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

5gmg[2] J SDL
2-azanyl-9-[(2~{R},3~{R},4~{S},5~{R})-5-(hydroxyme.. A 50.0
/43.6 6
/6 B3Y653_MACMU Toll-like receptor 7

5gmg[2] K SDL
2-azanyl-9-[(2~{R},3~{R},4~{S},5~{R})-5-(hydroxyme.. A 50.0
/43.6 6
/6 B3Y653_MACMU Toll-like receptor 7

8s9h[2] N ZWV
(3S)-3-{[5-amino-1-({3-methoxy-5-[1-(oxan-4-yl)pip.. A 50.0
/43.4 6
/6 G8E2R2_MACMU Toll-like receptor 7

8s9h[2] W ZWV
(3S)-3-{[5-amino-1-({3-methoxy-5-[1-(oxan-4-yl)pip.. A 33.3
/43.4 9
/9 G8E2R2_MACMU Toll-like receptor 7

8tty[2] N QEC
N~7~-butyl-2-({4-[(cyclobutylamino)methyl]-2-metho.. A 50.0
/43.4 6
/6 G8E2R2_MACMU Toll-like receptor 7

8tty[2] V QEC
N~7~-butyl-2-({4-[(cyclobutylamino)methyl]-2-metho.. A 62.5
/43.4 8
/8 G8E2R2_MACMU Toll-like receptor 7

6lw1[2] C EX3
2-ethoxy-8-(5-fluoranylpyridin-3-yl)-6-methyl-9-[[.. A 41.7
/43.3 12
/12 B3Y653_MACMU Toll-like receptor 7

6lw1[2] D EX3
2-ethoxy-8-(5-fluoranylpyridin-3-yl)-6-methyl-9-[[.. A 75.0
/43.3 4
/4 B3Y653_MACMU Toll-like receptor 7

6lvx[2] D EWL
6-azanyl-2-butoxy-9-(phenylmethyl)-7H-purin-8-one[.. A 50.0
/43.3 6
/6 B3Y653_MACMU Toll-like receptor 7

6lvx[2] P EWL
6-azanyl-2-butoxy-9-(phenylmethyl)-7H-purin-8-one[.. A 57.1
/43.3 7
/7 B3Y653_MACMU Toll-like receptor 7

6lvy[2] E EWU
6-azanyl-2-(2-methoxyethoxy)-9-(phenylmethyl)-7H-p.. A 50.0
/43.3 6
/6 B3Y653_MACMU Toll-like receptor 7

6lvy[2] S EWU
6-azanyl-2-(2-methoxyethoxy)-9-(phenylmethyl)-7H-p.. A 50.0
/43.3 6
/6 B3Y653_MACMU Toll-like receptor 7

3w3g[54] I NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

3w3g[123] J NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 2
/2 TLR8_HUMAN Toll-like receptor 8

3w3g[75] K NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

3w3g[73] L NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

3w3g[52] M NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

3w3n[6] N NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

3w3n[16] W NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. B 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

3w3n[28] X NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. B 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

3wn4[2] F NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

3wn4[2] I NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

4qbz[15] I NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

4qc0[41] H NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

4qdh[2] C NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 25.0
/40.6 4
/4 Q4G1L2_EPTBU TLR9_MOUSE Q4G1L2_EPTBU Variable lymphocyte receptor B, Toll-like receptor..

4qdh[2] D NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 0.0
/40.6 4
/4 Q4G1L2_EPTBU TLR9_MOUSE Q4G1L2_EPTBU Variable lymphocyte receptor B, Toll-like receptor..

4qdh[5] E NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 50.0
/40.6 6
/6 Q4G1L2_EPTBU TLR9_MOUSE Q4G1L2_EPTBU Variable lymphocyte receptor B, Toll-like receptor..

4qdh[2] G NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 40.0
/40.6 5
/6 Q4G1L2_EPTBU TLR9_MOUSE Q4G1L2_EPTBU Variable lymphocyte receptor B, Toll-like receptor..

4r0a[3] H NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

5awd[38] G NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

5gmf[3] X NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. B 0.0
/43.1 3
/3 B3Y653_MACMU Toll-like receptor 7

5gmf[46] BA NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. C 16.7
/43.1 6
/6 B3Y653_MACMU Toll-like receptor 7

5gmf[26] LA NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. D 16.7
/43.1 6
/6 B3Y653_MACMU Toll-like receptor 7

5gmg[31] H NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 20.0
/43.6 5
/5 B3Y653_MACMU Toll-like receptor 7

5gmh[26] J NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 0.0
/43.2 4
/4 B3Y653_MACMU Toll-like receptor 7

5hdh[13] H NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

5hdh[13] J NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

6lvx[1] E NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 37.5
/43.3 8
/8 B3Y653_MACMU Toll-like receptor 7

6zjz[1] L NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

7crf[4] DA NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 1
/1 TLR8_HUMAN Toll-like receptor 8

7ytp[2] K NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 0.0
/44.2 4
/4 B3Y653_MACMU Toll-like receptor 7

3w3j[2] M C09
2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-4-amine.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

3w3j[2] V C09
2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-4-amine.. A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

5zsi[2] J C09
2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-4-amine.. A 50.0
/43.2 6
/6 B3Y653_MACMU Toll-like receptor 7

5zsi[2] R C09
2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-4-amine.. A 80.0
/43.2 5
/5 B3Y653_MACMU Toll-like receptor 7

3w3k[2] I L07
2-propyl[1,3]thiazolo[4,5-c]quinolin-4-amine[17 at.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

3w3k[2] M L07
2-propyl[1,3]thiazolo[4,5-c]quinolin-4-amine[17 at.. A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

5zsh[2] R L07
2-propyl[1,3]thiazolo[4,5-c]quinolin-4-amine[17 at.. A 50.0
/43.2 6
/6 B3Y653_MACMU Toll-like receptor 7

5zsh[2] S L07
2-propyl[1,3]thiazolo[4,5-c]quinolin-4-amine[17 at.. A 75.0
/43.2 4
/4 B3Y653_MACMU Toll-like receptor 7

3w3l[8] JA RX8
1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino.. A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

3w3l[8] KA RX8
1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino.. A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

5gmh[2] EA RX8
1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino.. A 66.7
/43.2 6
/6 B3Y653_MACMU Toll-like receptor 7

5gmh[2] F RX8
1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino.. A 50.0
/43.2 6
/6 B3Y653_MACMU Toll-like receptor 7

5zsf[2] O 6T0
1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine[1.. A 40.0
/43.2 5
/5 B3Y653_MACMU Toll-like receptor 7

5zsf[2] U 6T0
1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine[1.. A 50.0
/43.2 4
/4 B3Y653_MACMU Toll-like receptor 7

5zsg[2] M 9K3
1-{4-amino-2-[(ethylamino)methyl]-1H-imidazo[4,5-c.. A 50.0
/43.2 6
/6 G7NS93_MACMU Toll-like receptor 7

5zsg[2] X 9K3
1-{4-amino-2-[(ethylamino)methyl]-1H-imidazo[4,5-c.. A 57.1
/43.2 7
/7 G7NS93_MACMU Toll-like receptor 7

5zsj[2] E 9JR
4-azanyl-2-butoxy-8-[[3-(pyrrolidin-1-ylmethyl)phe.. A 50.0
/43.2 6
/6 B3Y653_MACMU Toll-like receptor 7

5zsj[2] V 9JR
4-azanyl-2-butoxy-8-[[3-(pyrrolidin-1-ylmethyl)phe.. A 42.9
/43.2 7
/7 B3Y653_MACMU Toll-like receptor 7

5zsn[2] GA ACK
2',3'- cyclic AMP [22 atoms] A 50.0
/43.2 6
/6 B3Y653_MACMU Toll-like receptor 7

5zsn[2] Z ACK
2',3'- cyclic AMP [22 atoms] A 28.6
/43.2 7
/7 B3Y653_MACMU Toll-like receptor 7

6lvz[2] S EWX
6-azanyl-2-(2-methoxyethoxy)-9-(pyridin-3-ylmethyl.. A 50.0
/43.2 6
/6 B3Y653_MACMU Toll-like receptor 7

6lvz[2] T EWX
6-azanyl-2-(2-methoxyethoxy)-9-(pyridin-3-ylmethyl.. A 50.0
/43.2 8
/8 B3Y653_MACMU Toll-like receptor 7

6lw0[2] CA EX0
2-ethoxy-8-(5-fluoranylpyridin-3-yl)-9-[[4-[[(1S,4.. A 57.1
/43.2 7
/7 B3Y653_MACMU Toll-like receptor 7

6lw0[2] S EX0
2-ethoxy-8-(5-fluoranylpyridin-3-yl)-9-[[4-[[(1S,4.. A 50.0
/43.2 8
/8 B3Y653_MACMU Toll-like receptor 7

8ttz[2] EA QCX
(3S)-3-({5-amino-1-[(2-methoxy-4-{[(oxan-4-yl)amin.. A 50.0
/43.2 6
/6 G8E2R2_MACMU Toll-like receptor 7

5zsl[4] T 9K9
2-amino-9-[(2S,3aR,4R,6R,6aR)-2-hydroxy-6-(hydroxy.. A 50.0
/43.0 6
/6 B3Y653_MACMU Toll-like receptor 7

5zsl[4] U 9K9
2-amino-9-[(2S,3aR,4R,6R,6aR)-2-hydroxy-6-(hydroxy.. A 37.5
/43.0 8
/8 B3Y653_MACMU Toll-like receptor 7

5awd[2] E IDQ
1-[[4-(aminomethyl)phenyl]methyl]-2-butyl-imidazo[.. A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

5awd[2] E IDQ
1-[[4-(aminomethyl)phenyl]methyl]-2-butyl-imidazo[.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

5zsa[10] P IDQ
1-[[4-(aminomethyl)phenyl]methyl]-2-butyl-imidazo[.. A 50.0
/43.1 6
/6 B3Y653_MACMU Toll-like receptor 7

5zsa[10] Y IDQ
1-[[4-(aminomethyl)phenyl]methyl]-2-butyl-imidazo[.. A 62.5
/43.1 8
/8 B3Y653_MACMU Toll-like receptor 7

5gmf[4] Y GMP
GUANOSINE[20 atoms] A 50.0
/43.1 6
/6 B3Y653_MACMU Toll-like receptor 7

5gmf[4] Z GMP
GUANOSINE[20 atoms] A 60.0
/43.1 5
/5 B3Y653_MACMU Toll-like receptor 7

6if5[2] FA 23G
GUANOSINE-5'-PHOSPHATE-2',3'-CYCLIC PHOSPHATE [23 .. A 50.0
/43.2 6
/6 B3Y653_MACMU Toll-like receptor 7

6if5[2] GA 23G
GUANOSINE-5'-PHOSPHATE-2',3'-CYCLIC PHOSPHATE [23 .. A 37.5
/43.2 8
/8 B3Y653_MACMU Toll-like receptor 7

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

METAL

1041 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

5gmf[3] O CA
CALCIUM ION[1 atoms] A 0.0
/43.1 1
/1 B3Y653_MACMU Toll-like receptor 7

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

OTHERPOLY

1041 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

3w3j[16] C alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. A 100.0
/100.0 14
/14 TLR8_HUMAN Toll-like receptor 8

5az5[2] G alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

7crf[2] G alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. B 100.0
/100.0 8
/8 TLR8_HUMAN Toll-like receptor 8

3w3k[20] C alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose.. A 100.0
/100.0 13
/13 TLR8_HUMAN Toll-like receptor 8

3w3k[20] E alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose.. A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

5hdh[12] D alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose.. A 100.0
/100.0 8
/8 TLR8_HUMAN Toll-like receptor 8

6ty5[11] C alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose.. A 100.0
/100.0 14
/14 TLR8_HUMAN Toll-like receptor 8

3wn4[4] B alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose.. A 100.0
/100.0 14
/14 TLR8_HUMAN Toll-like receptor 8

4qbz[1] C alpha-D-mannopyranose-(2-3)-[beta-D-mannopyranose-.. A 100.0
/100.0 14
/14 TLR8_HUMAN Toll-like receptor 8

4r07[6] K alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(.. C 100.0
/100.0 13
/13 TLR8_HUMAN Toll-like receptor 8

5az5[5] M alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(.. C 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

5hdh[1] B alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(.. A 100.0
/100.0 13
/13 TLR8_HUMAN Toll-like receptor 8

5z14[1] F alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-.. B 100.0
/100.0 14
/14 TLR8_HUMAN Toll-like receptor 8

6v9u[1] H alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-.. B 100.0
/100.0 11
/11 TLR8_HUMAN Toll-like receptor 8

6zjz[1] C alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. A 100.0
/100.0 15
/15 TLR8_HUMAN Toll-like receptor 8

6zjz[1] E alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

7crf[1] C alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. A 100.0
/100.0 14
/14 TLR8_HUMAN Toll-like receptor 8

7crf[1] F alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. B 100.0
/100.0 14
/14 TLR8_HUMAN Toll-like receptor 8

7ytx[2] E alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. A 100.0
/100.0 11
/11 TLR8_HUMAN Toll-like receptor 8

7crf[1] H alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose.. B 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

7ytx[1] C alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-.. A 100.0
/100.0 14
/14 TLR8_HUMAN Toll-like receptor 8

3w3g[20] C beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. A 100.0
/100.0 13
/13 TLR8_HUMAN Toll-like receptor 8

3w3g[23] D beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. A 100.0
/100.0 12
/12 TLR8_HUMAN Toll-like receptor 8

3w3g[37] E beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. A 100.0
/100.0 11
/11 TLR8_HUMAN Toll-like receptor 8

3w3n[3] G beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. A 100.0
/100.0 1
/1 TLR8_HUMAN Toll-like receptor 8

6lvz[4] C beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. A 37.5
/43.2 8
/8 B3Y653_MACMU Toll-like receptor 7

6ty5[12] D beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

3w3g[1] F 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. B 100.0
/100.0 13
/13 TLR8_HUMAN Toll-like receptor 8

3w3j[43] D 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

3w3j[12] D 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. B 100.0
/100.0 1
/1 TLR8_HUMAN Toll-like receptor 8

4r09[4] G 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

5gmf[22] I 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. A 16.7
/43.1 6
/6 B3Y653_MACMU Toll-like receptor 7

5gmf[43] J 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. A 37.5
/43.1 8
/8 B3Y653_MACMU Toll-like receptor 7

5hdh[1] C 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

7ytp[2] C 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. A 37.5
/44.2 8
/8 B3Y653_MACMU Toll-like receptor 7

7ytp[2] D 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. A 85.7
/44.2 7
/8 B3Y653_MACMU Toll-like receptor 7

7ytp[2] E 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. A 16.7
/44.2 6
/6 B3Y653_MACMU Toll-like receptor 7

5zsn[1] F beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. B 33.3
/43.2 9
/9 B3Y653_MACMU Toll-like receptor 7

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

HOMO

1041 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

3w3g[69] B TLR8_HUMAN Toll-like receptor 8[743 aa] A 100.0
/100.0 26
/26 TLR8_HUMAN Toll-like receptor 8

3wn4[2] A TLR8_HUMAN Toll-like receptor 8[747 aa] A 100.0
/100.0 24
/24 TLR8_HUMAN Toll-like receptor 8

6zjz[10] B TLR8_HUMAN Toll-like receptor 8[740 aa] A 100.0
/100.0 32
/32 TLR8_HUMAN Toll-like receptor 8

6wml[1] C TLR8_HUMAN Toll-like receptor 8[681 aa] D 100.0
/100.0 43
/43 TLR8_HUMAN Toll-like receptor 8

5gmf[50] C B3Y653_MACMU Toll-like receptor 7[776 aa] A 51.2
/43.1 43
/47 B3Y653_MACMU Toll-like receptor 7

7cyn[1] B TLR7_HUMAN Toll-like receptor 7[786 aa] A 100.0
/43.2 1
/1 TLR7_HUMAN Toll-like receptor 7

7cyn[1] A TLR7_HUMAN Toll-like receptor 7[786 aa] B 100.0
/43.2 1
/1 TLR7_HUMAN Toll-like receptor 7

7ytp[2] B B3Y653_MACMU Toll-like receptor 7[731 aa] A 65.4
/44.2 26
/26 B3Y653_MACMU Toll-like receptor 7

8ttz[2] B G8E2R2_MACMU Toll-like receptor 7[772 aa] A 15.8
/43.2 19
/24 G8E2R2_MACMU Toll-like receptor 7

1fyw[4] A TLR2_HUMAN TOLL-LIKE RECEPTOR 2[149 aa] A 26.7
/43.0 15
/16 TLR2_HUMAN TOLL-LIKE RECEPTOR 2

1o77[4] B TLR2_HUMAN TOLL-LIKE RECEPTOR 2[135 aa] A 23.1
/41.4 13
/14 TLR2_HUMAN TOLL-LIKE RECEPTOR 2

1o77[4] C TLR2_HUMAN TOLL-LIKE RECEPTOR 2[135 aa] A 20.0
/41.4 5
/6 TLR2_HUMAN TOLL-LIKE RECEPTOR 2

2j67[1] A TLR10_HUMAN TOLL LIKE RECEPTOR 10[141 aa] B 28.6
/40.6 14
/14 TLR10_HUMAN TOLL LIKE RECEPTOR 10

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

PRECIPITANT

1041 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

3w3g[1] O BU3
(R,R)-2,3-BUTANEDIOL[6 atoms] A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

3w3j[1] IA GOL
GLYCEROL[6 atoms] B 100.0
/100.0 2
/2 TLR8_HUMAN Toll-like receptor 8

3w3n[1] P GOL
GLYCEROL[6 atoms] A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

5hdh[1] N MES
2-(N-MORPHOLINO)-ETHANESULFONIC ACID[12 atoms] A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

6zjz[1] T FMT
FORMIC ACID[3 atoms] B 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

3w3j[2] AA SO4
SULFATE ION[5 atoms] A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

3w3j[8] N SO4
SULFATE ION[5 atoms] A 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

3w3j[9] O SO4
SULFATE ION[5 atoms] A 100.0
/100.0 2
/2 TLR8_HUMAN Toll-like receptor 8

3w3j[2] P SO4
SULFATE ION[5 atoms] A 100.0
/100.0 2
/2 TLR8_HUMAN Toll-like receptor 8

3w3j[1] Q SO4
SULFATE ION[5 atoms] A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

3w3j[2] R SO4
SULFATE ION[5 atoms] A 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

3w3j[6] S SO4
SULFATE ION[5 atoms] A 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

3w3j[4] T SO4
SULFATE ION[5 atoms] A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

3w3j[13] U SO4
SULFATE ION[5 atoms] A 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

3w3j[16] CA SO4
SULFATE ION[5 atoms] B 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

3w3j[1] GA SO4
SULFATE ION[5 atoms] B 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

3w3l[1] DA SO4
SULFATE ION[5 atoms] B 100.0
/100.0 1
/1 TLR8_HUMAN Toll-like receptor 8

4qdh[2] H SO4
SULFATE ION[5 atoms] A 0.0
/40.6 3
/3 Q4G1L2_EPTBU TLR9_MOUSE Q4G1L2_EPTBU Variable lymphocyte receptor B, Toll-like receptor..

4qdh[2] I SO4
SULFATE ION[5 atoms] A 0.0
/40.6 3
/3 Q4G1L2_EPTBU TLR9_MOUSE Q4G1L2_EPTBU Variable lymphocyte receptor B, Toll-like receptor..

4qdh[3] J SO4
SULFATE ION[5 atoms] A 50.0
/40.6 2
/2 Q4G1L2_EPTBU TLR9_MOUSE Q4G1L2_EPTBU Variable lymphocyte receptor B, Toll-like receptor..

4qdh[2] K SO4
SULFATE ION[5 atoms] A 100.0
/40.6 2
/2 Q4G1L2_EPTBU TLR9_MOUSE Q4G1L2_EPTBU Variable lymphocyte receptor B, Toll-like receptor..

5gmh[21] AA SO4
SULFATE ION[5 atoms] A 0.0
/43.2 3
/3 B3Y653_MACMU Toll-like receptor 7

5gmh[12] BA SO4
SULFATE ION[5 atoms] A 0.0
/43.2 3
/3 B3Y653_MACMU Toll-like receptor 7

5gmh[7] N SO4
SULFATE ION[5 atoms] A 0.0
/43.2 1
/1 B3Y653_MACMU Toll-like receptor 7

5gmh[19] NA SO4
SULFATE ION[5 atoms] A 33.3
/43.2 3
/3 B3Y653_MACMU Toll-like receptor 7

5gmh[60] O SO4
SULFATE ION[5 atoms] A 0.0
/43.2 3
/3 B3Y653_MACMU Toll-like receptor 7

5gmh[16] P SO4
SULFATE ION[5 atoms] A 0.0
/43.2 4
/4 B3Y653_MACMU Toll-like receptor 7

5gmh[16] R SO4
SULFATE ION[5 atoms] A 0.0
/43.2 3
/3 B3Y653_MACMU Toll-like receptor 7

5gmh[18] S SO4
SULFATE ION[5 atoms] A 0.0
/43.2 2
/2 B3Y653_MACMU Toll-like receptor 7

5gmh[13] T SO4
SULFATE ION[5 atoms] A 20.0
/43.2 5
/5 B3Y653_MACMU Toll-like receptor 7

5gmh[2] U SO4
SULFATE ION[5 atoms] A 0.0
/43.2 3
/3 B3Y653_MACMU Toll-like receptor 7

5gmh[5] V SO4
SULFATE ION[5 atoms] A 44.4
/43.2 9
/9 B3Y653_MACMU Toll-like receptor 7

5gmh[5] W SO4
SULFATE ION[5 atoms] A 0.0
/43.2 5
/5 B3Y653_MACMU Toll-like receptor 7

5gmh[7] X SO4
SULFATE ION[5 atoms] A 0.0
/43.2 2
/2 B3Y653_MACMU Toll-like receptor 7

5gmh[2] RA SO4
SULFATE ION[5 atoms] B 33.3
/43.2 9
/9 B3Y653_MACMU Toll-like receptor 7

5gmh[10] TA SO4
SULFATE ION[5 atoms] B 0.0
/43.2 3
/3 B3Y653_MACMU Toll-like receptor 7

5hdh[1] K SO4
SULFATE ION[5 atoms] A 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

5hdh[2] L SO4
SULFATE ION[5 atoms] A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

5hdh[1] M SO4
SULFATE ION[5 atoms] A 100.0
/100.0 1
/1 TLR8_HUMAN Toll-like receptor 8

5zsa[7] EA SO4
SULFATE ION[5 atoms] A 100.0
/43.1 1
/1 B3Y653_MACMU Toll-like receptor 7

5zsa[6] AA SO4
SULFATE ION[5 atoms] B 50.0
/43.2 2
/2 B3Y653_MACMU Toll-like receptor 7

5zsa[12] EA SO4
SULFATE ION[5 atoms] B 100.0
/43.2 3
/3 B3Y653_MACMU Toll-like receptor 7

5zsb[6] DA SO4
SULFATE ION[5 atoms] A 50.0
/43.1 2
/2 B3Y653_MACMU Toll-like receptor 7

5zsc[1] V SO4
SULFATE ION[5 atoms] A 0.0
/43.1 2
/2 B3Y653_MACMU Toll-like receptor 7

5zsj[9] U SO4
SULFATE ION[5 atoms] A 28.6
/43.2 7
/7 B3Y653_MACMU Toll-like receptor 7

6if5[2] S SO4
SULFATE ION[5 atoms] A 0.0
/43.2 1
/1 B3Y653_MACMU Toll-like receptor 7

6if5[2] W SO4
SULFATE ION[5 atoms] A 0.0
/43.2 4
/4 B3Y653_MACMU Toll-like receptor 7

6if5[1] X SO4
SULFATE ION[5 atoms] A 0.0
/43.2 2
/2 B3Y653_MACMU Toll-like receptor 7

6if5[1] OA SO4
SULFATE ION[5 atoms] B 0.0
/43.1 3
/3 B3Y653_MACMU Toll-like receptor 7

8tty[1] W SO4
SULFATE ION[5 atoms] A 100.0
/43.4 2
/2 G8E2R2_MACMU Toll-like receptor 7

8tty[1] W SO4
SULFATE ION[5 atoms] B 60.0
/43.4 5
/5 G8E2R2_MACMU Toll-like receptor 7

5gmg[1] O PO4
PHOSPHATE ION[5 atoms] B 0.0
/43.6 2
/2 B3Y653_MACMU Toll-like receptor 7

5zsn[2] CA PO4
PHOSPHATE ION[5 atoms] A 33.3
/43.2 3
/3 B3Y653_MACMU Toll-like receptor 7

5zsn[2] O PO4
PHOSPHATE ION[5 atoms] A 0.0
/43.2 3
/3 B3Y653_MACMU Toll-like receptor 7

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

MONOMER
1041
	pdb_id	a¹	identity[%]²	description
	4qbz	A	100.0	TLR8_HUMAN Toll-like receptor 8
	7cyn	B	43.2	TLR7_HUMAN Toll-like receptor 7
	1fyw	A	43.0	TLR2_HUMAN TOLL-LIKE RECEPTOR 2
	1.a¹:asym_id for the homologue. 2.identity[%]²:sequence identity between the query and the homologue.

Contact Molecules for Homologous Proteins

Summary Bars[40 %]

UniProt Feature Tables [Q9NR97(TLR8_HUMAN)]