Protein Model on 8pfi_A_1_O_1
(TEMPLATE: 
8pfi
)Protein Model on 8pfi_A_1_O_1
(TEMPLATE: 8pfi
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ALL MOLECULES IN THE BIOLOGICAL UNIT: |
| MOLECULES | contact sites | |||||
| model | mark | query | asym_id oper (auth_asym_id) |
type | description | a(query A) |
| 1 | a | A(TLR8_HUMAN) | A 1 (A) | polymer(polypeptide(L)) [733 aa] | Toll-like receptor 8 :TLR8_HUMAN | |
| 2 | b | O 1 (A) | non-polymer(YHG) | (3~{S})-~{N}-[4-[[5-(1,6-dimethylpyrazolo[3,4-b]pyridin-4-yl)-3-methyl-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridin-1-yl]methyl]-1-bicyclo[2.2.2]octanyl]morpholine-3-carboxamide | 261F 346F 348Y 349I 350K 351G 352S 376G 378V 403I 405F 427E 490L (identity: 100.0 %/93.0 %) | |
| ALIGNMENTS |
| MODEL[1] Protein A "queryA" TEMPLATE:8pfi_A_1 identity=93.0% |
queryA 31:SRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNLREL: 130
:********************************************************************* ******************:
8pfi_A_1 5:SRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXXXXXXXXXGLNITDGAFLNLKNLREL: 104
SecStr : SSEEEE SSSEEEE SS SS S S TT SEEE SS EE TTSS S TT EEE SS ------------- EE TTSSTT SS EE:
ExpBur :ebeebbeeeeeeeeebbebeebebeebbeebbeebbebebbebebeebeeebbeebeebeebbbbebee-------------ebebeebbbeebeebeeb:
queryA 131:LLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLS: 230
:***************************************************** ********************************************:
8pfi_A_1 105:LLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFXXXCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLS: 204
SecStr :E SS SS TT TT SEEE SS EE TTTTTT TT EEE TTSS --- EE TTTTTT TT EEE SS SS SS TT SEEE T:
ExpBur :bbbebebeebbeebbebbbebbbbebebeebeeebbbebeebbebebbbbbbe---eeebeeeebbbeebeebebbbbbbbbbeebbeebbebbeebebb:
queryA 231:NTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASG: 330
:****************************************************************************************************:
8pfi_A_1 205:NTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASG: 304
SecStr :TS EE TTTTTT TT EEE TTSS SS SS TTS EE TTTTSS TT EEE SS S GGGGTT TT EEE SS HHHHHT :
ExpBur :bbebeebbeeebbebeebebbbbbbbbbbeeeeebeeeebeeeeebebeeebbeebeebeebbbbbbbbeebebbbbeebeebebbbbbbbebbebbeeb:
Contact : b
queryA 331:AFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRI: 430
:****************************************************************************************************:
8pfi_A_1 305:AFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRI: 404
SecStr :GGGGG TT EEE S TT SS GGGGG TT EEE TT SEE TTTTGGGTT SS EEE S EE GGGGTT SS EEE SS :
ExpBur :ebbeebeebeebbbbbbeeeeeeeeebebbeebeebeebebbbbbbbbbbebeeebbebbbebeebebbbbbebebeebebbbbeebeebeebbbbebeb:
Contact : b bbbbb b b b b b
queryA 431:SPLVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIP: 530
:** *********************************************************************:
8pfi_A_1 405:SPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIP: 504
SecStr : ----------------------------- TTS SSS S SS HHHHTTSEEEE SS SS TTTTTT EEEEE SS B S TTSSST:
ExpBur :ee-----------------------------eeeeeebbeeeebbeeebeeeeebbbbbebebeebbeebbeebbebbbbbbbebebebebebebbeebe:
Contact : b
queryA 531:HVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNR: 630
:************************************** *************************************************** *:
8pfi_A_1 505:HVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFXXXXXTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWXXXXXR: 604
SecStr :T SEEE SS B STTTTTT TT EEE TT TTT ----- GGGGG SS EEE TT S S EESS EEE TTS HHHH ----- :
ExpBur :ebebbbbbebebebbeeebbbbbeebebbbbbebeebb-----ebbbebbeebeebeebbbbebebeebeebeebebebbeebbbbbbbbeebb-----e:
queryA 631:YISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG: 730
:****************************************************************************************************:
8pfi_A_1 605:YISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG: 704
SecStr : TTTTTEETT EEE SS S HHHHHTS TT SEEE SS S GGGGGG TT EEE SS S GGGT SS EEE SS TT:
ExpBur :beebbeebeebeebbbbebebeebeeebbebbbebbeebbbbebebeebebebbeebeebebbbbeebebeebbeebeeebebbbebbbbebebeebbee:
queryA 731:FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE: 818
:****************************************************************************************:
8pfi_A_1 705:FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE: 792
SecStr :SSSS TT EEE SS TTTS SS EEE TT EE SGGGHHHHHHHHH SSSB GGGSBEEESTTTBTSBTTS :
ExpBur :bbbebeebbbbbbbebebeebeeebbeeeeebebeebbbbebebebeeebeebbbbbeeeeebebeebbbbebeeeeeebeebbbeee:
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[assembly_id:1]
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