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		Contact Molecules for Homologous Proteins
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PID

QueryLength

Homolgous Sequence in PDB

UniProt Query

TITLE

2684896

1041

Q9NR97(TLR8_HUMAN)

RecName: Full=Toll-like receptor 8 ;AltName: CD_antigen=CD288;Flags: Precursor;

QUERYSEQ

MENMFLQSSMLTCIFLLISGSCELCAEENFSRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTE
LSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLR
KINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKDTRQSYANSSSFQRH
IRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLT
DKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKT
INKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELTTCVSDVTAVILFFFTFFITTMVMLAALAHHLFYWDVWFIYNVCLAKVKGYRSLSTSQTFYDAYISYDTKDASVTDWVINE
LRYHLEESRDKNVLLCLEERDWDPGLAIIDNLMQSINQSKKTVFVLTKKYAKSWNFKTAFYLALQRLMDENMDVIIFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFWQTLRNVVLTENDSRYNNMYVDSIKQY

[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]

UniProt Feature Tables [Q9NR97(TLR8_HUMAN)]

1041
	region	name	description
	1-26	SIGNAL
	27-1041	CHAIN	/note="Toll-like receptor 8" /id="PRO_0000034735"
	27-827	TOPO_DOM	/note="Extracellular"
	828-848	TRANSMEM	/note="Helical"
	849-1041	TOPO_DOM	/note="Cytoplasmic"
	126-147	REPEAT	/note="LRR 1"
	148-168	REPEAT	/note="LRR 2"
	171-193	REPEAT	/note="LRR 3"
	202-223	REPEAT	/note="LRR 4"
	224-244	REPEAT	/note="LRR 5"
	247-268	REPEAT	/note="LRR 6"
	288-309	REPEAT	/note="LRR 7"
	312-334	REPEAT	/note="LRR 8"
	338-360	REPEAT	/note="LRR 9"
	368-389	REPEAT	/note="LRR 10"
	395-416	REPEAT	/note="LRR 11"
	419-440	REPEAT	/note="LRR 12"
	482-503	REPEAT	/note="LRR 13"
	506-527	REPEAT	/note="LRR 14"
	531-551	REPEAT	/note="LRR 15"
	555-577	REPEAT	/note="LRR 16"
	585-606	REPEAT	/note="LRR 17"
	609-630	REPEAT	/note="LRR 18"
	640-661	REPEAT	/note="LRR 19"
	665-685	REPEAT	/note="LRR 20"
	689-710	REPEAT	/note="LRR 21"
	713-734	REPEAT	/note="LRR 22"
	737-758	REPEAT	/note="LRR 23"
	772-824	DOMAIN	/note="LRRCT"
	878-1022	DOMAIN	/note="TIR"
	1-1041	DISORDER	predicted by DISOPRED

MONOMER

1041

pdb_id a¹ identity[%]² description

4qbz A 100.0 TLR8_HUMAN Toll-like receptor 8

1.a¹:asym_id for the homologue. 2.identity[%]²:sequence identity between the query and the homologue.

COMPOUND

1041 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

3w3g[54] I NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

3w3g[73] J NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 2
/2 TLR8_HUMAN Toll-like receptor 8

3w3g[37] K NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

3w3g[71] L NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

3w3g[52] M NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

3w3n[6] N NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

3w3n[16] W NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. B 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

3w3n[28] X NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. B 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

3wn4[2] F NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

3wn4[2] I NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

4qbz[13] I NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

4qc0[4] H NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

4r0a[3] H NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

5awd[5] G NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

5hdh[1] E NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

5hdh[13] H NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

5hdh[13] J NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

6ty5[12] J NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

6zjz[1] L NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

7crf[2] DA NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. A 100.0
/100.0 1
/1 TLR8_HUMAN Toll-like receptor 8

3w3j[2] M C09
2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-4-amine.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

3w3j[2] V C09
2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-4-amine.. A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

3w3k[2] I L07
2-propyl[1,3]thiazolo[4,5-c]quinolin-4-amine[17 at.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

3w3k[2] M L07
2-propyl[1,3]thiazolo[4,5-c]quinolin-4-amine[17 at.. A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

3w3l[8] JA RX8
1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino.. A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

3w3l[8] KA RX8
1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino.. A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

3wn4[2] E D87
2-butylfuro[2,3-c]quinolin-4-amine[18 atoms] A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

4qbz[2] O D80
2-butyl[1,3]oxazolo[4,5-c]quinolin-4-amine[18 atom.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

4qbz[2] P D80
2-butyl[1,3]oxazolo[4,5-c]quinolin-4-amine[18 atom.. A 100.0
/100.0 8
/8 TLR8_HUMAN Toll-like receptor 8

4qc0[2] J XG1
2-butyl-2H-pyrazolo[3,4-c]quinolin-4-amine[18 atom.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

4qc0[2] K XG1
2-butyl-2H-pyrazolo[3,4-c]quinolin-4-amine[18 atom.. A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

4r07[14] Q URI
URIDINE[17 atoms] A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

4r07[14] X URI
URIDINE[17 atoms] A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

4r07[8] R UCG
3'-O-[(R)-{[(2R,3aR,4R,6R,6aR)-6-(2-amino-6-oxo-1,.. A 100.0
/100.0 15
/15 TLR8_HUMAN Toll-like receptor 8

4r09[4] Q 06S
O-[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3,6-dihydro-9H-p.. A 100.0
/100.0 15
/15 TLR8_HUMAN Toll-like receptor 8

4r09[4] R UPT
1-[(2R,3aR,4R,6R,6aR)-2-hydroxy-6-(hydroxymethyl)-.. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

4r09[4] V UPT
1-[(2R,3aR,4R,6R,6aR)-2-hydroxy-6-(hydroxymethyl)-.. A 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

4r6a[2] M HB2
1-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl).. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

4r6a[2] N HB2
1-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl).. A 100.0
/100.0 11
/11 TLR8_HUMAN Toll-like receptor 8

5awa[2] E M8D
5-[[3-(aminomethyl)phenyl]methyl]-3-pentyl-quinoli.. A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

5awa[2] E M8D
5-[[3-(aminomethyl)phenyl]methyl]-3-pentyl-quinoli.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

5awb[2] E M0A
1-[[3-(aminomethyl)phenyl]methyl]-2-butyl-imidazo[.. A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

5awb[2] E M0A
1-[[3-(aminomethyl)phenyl]methyl]-2-butyl-imidazo[.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

5awc[4] T M4D
5-(4-azanylbutyl)-3-pentyl-quinolin-2-amine[21 ato.. A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

5awc[4] U M4D
5-(4-azanylbutyl)-3-pentyl-quinolin-2-amine[21 ato.. A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

5awd[2] E IDQ
1-[[4-(aminomethyl)phenyl]methyl]-2-butyl-imidazo[.. A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

5awd[2] E IDQ
1-[[4-(aminomethyl)phenyl]methyl]-2-butyl-imidazo[.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

5az5[4] Q MBL
1-pentyl-4-phenyl-imidazol-2-amine[17 atoms] A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

5az5[4] U MBL
1-pentyl-4-phenyl-imidazol-2-amine[17 atoms] A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

5wyx[2] M CU8
7-(3-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carb.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

5wyx[2] N CU8
7-(3-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carb.. A 100.0
/100.0 11
/11 TLR8_HUMAN Toll-like receptor 8

5wyz[2] I 7VF
4-(3-methyl-4-oxidanyl-phenyl)quinolin-7-ol[19 ato.. A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

5wyz[2] M 7VF
4-(3-methyl-4-oxidanyl-phenyl)quinolin-7-ol[19 ato.. A 100.0
/100.0 11
/11 TLR8_HUMAN Toll-like receptor 8

5z14[2] I 7VC
4-(7-methoxyquinolin-4-yl)-2-methyl-phenol[20 atom.. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

5z14[2] L 7VC
4-(7-methoxyquinolin-4-yl)-2-methyl-phenol[20 atom.. A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

5z15[2] I 7VL
4-(7-chloranylquinolin-4-yl)-2-methyl-phenol[19 at.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

5z15[2] N 7VL
4-(7-chloranylquinolin-4-yl)-2-methyl-phenol[19 at.. A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

6kya[2] I DY3
3-[5-methylsulfanyl-4-(3,4,5-trimethylphenyl)-1,2,.. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

6kya[2] N DY3
3-[5-methylsulfanyl-4-(3,4,5-trimethylphenyl)-1,2,.. A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

6ty5[1] O O0W
5-methyl-7-(7-methyl-2-piperidin-4-yl-indazol-5-yl.. B 100.0
/100.0 11
/11 TLR8_HUMAN Toll-like receptor 8

6ty5[1] V O0W
5-methyl-7-(7-methyl-2-piperidin-4-yl-indazol-5-yl.. B 100.0
/100.0 8
/8 TLR8_HUMAN Toll-like receptor 8

6v9u[2] AA QSM
2-(3,4-dimethoxyphenyl)-5-(piperidin-4-yl)-3-(prop.. A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

6v9u[2] R QSM
2-(3,4-dimethoxyphenyl)-5-(piperidin-4-yl)-3-(prop.. A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

6wml[4] GA U57
(2R)-2-[(2-amino-7-fluoropyrido[3,2-d]pyrimidin-4-.. A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

6wml[4] X U57
(2R)-2-[(2-amino-7-fluoropyrido[3,2-d]pyrimidin-4-.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

6wml[2] Q MAN
alpha-D-mannopyranose[11 atoms] A 100.0
/100.0 2
/2 TLR8_HUMAN Toll-like receptor 8

6zjz[2] N QLH
5-[(3~{R},5~{S})-3-azanyl-5-(trifluoromethyl)piper.. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

6zjz[2] S QLH
5-[(3~{R},5~{S})-3-azanyl-5-(trifluoromethyl)piper.. A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

7crf[2] I GD0
1-[2-(ethoxymethyl)-4-iodanyl-5-phenyl-imidazol-1-.. A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

7crf[2] U GD0
1-[2-(ethoxymethyl)-4-iodanyl-5-phenyl-imidazol-1-.. A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

7r52[2] O I6A
5-methoxy-6-pyridin-4-yl-1~{H}-indole[17 atoms] A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

7r52[2] V I6A
5-methoxy-6-pyridin-4-yl-1~{H}-indole[17 atoms] A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

7r53[2] O I5N
5-cyclopropyl-6-(2,6-dimethylpyridin-4-yl)-~{N}-[(.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

7r53[2] P I5N
5-cyclopropyl-6-(2,6-dimethylpyridin-4-yl)-~{N}-[(.. A 100.0
/100.0 12
/12 TLR8_HUMAN Toll-like receptor 8

7r54[2] O I5B
(5-methoxy-6-pyridin-4-yl-1~{H}-indazol-3-yl)-(4-m.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

7r54[2] P I5B
(5-methoxy-6-pyridin-4-yl-1~{H}-indazol-3-yl)-(4-m.. A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

7rc9[2] P RQY
2-(2,6-dimethylpyridin-4-yl)-5-(piperidin-4-yl)-3-.. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

7rc9[2] X RQY
2-(2,6-dimethylpyridin-4-yl)-5-(piperidin-4-yl)-3-.. A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

7ytx[2] I JRI
(2R,6R)-4-(8-cyanoquinolin-5-yl)-N-[(3S,4R)-4-fluo.. A 100.0
/100.0 12
/12 TLR8_HUMAN Toll-like receptor 8

7ytx[2] S JRI
(2R,6R)-4-(8-cyanoquinolin-5-yl)-N-[(3S,4R)-4-fluo.. A 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

8pfi[2] O YHG
(3~{S})-~{N}-[4-[[5-(1,6-dimethylpyrazolo[3,4-b]py.. A 100.0
/100.0 13
/13 TLR8_HUMAN Toll-like receptor 8

8pfi[2] P YHG
(3~{S})-~{N}-[4-[[5-(1,6-dimethylpyrazolo[3,4-b]py.. A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

OTHERPOLY

1041 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

3w3g[20] C beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. A 100.0
/100.0 13
/13 TLR8_HUMAN Toll-like receptor 8

3w3g[23] D beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. A 100.0
/100.0 12
/12 TLR8_HUMAN Toll-like receptor 8

3w3g[37] E beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. A 100.0
/100.0 11
/11 TLR8_HUMAN Toll-like receptor 8

3w3n[3] G beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. A 100.0
/100.0 1
/1 TLR8_HUMAN Toll-like receptor 8

6ty5[12] D beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

3w3g[1] F 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. B 100.0
/100.0 13
/13 TLR8_HUMAN Toll-like receptor 8

3w3j[43] D 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

3w3j[12] D 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. B 100.0
/100.0 1
/1 TLR8_HUMAN Toll-like receptor 8

4r09[4] G 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

5hdh[1] C 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. A 100.0
/100.0 7
/7 TLR8_HUMAN Toll-like receptor 8

3w3j[16] C alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. A 100.0
/100.0 14
/14 TLR8_HUMAN Toll-like receptor 8

5az5[2] G alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

7crf[2] G alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. B 100.0
/100.0 8
/8 TLR8_HUMAN Toll-like receptor 8

3w3k[20] C alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose.. A 100.0
/100.0 13
/13 TLR8_HUMAN Toll-like receptor 8

3w3k[20] E alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose.. A 100.0
/100.0 9
/9 TLR8_HUMAN Toll-like receptor 8

5hdh[12] D alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose.. A 100.0
/100.0 8
/8 TLR8_HUMAN Toll-like receptor 8

6ty5[11] C alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose.. A 100.0
/100.0 14
/14 TLR8_HUMAN Toll-like receptor 8

3wn4[4] B alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose.. A 100.0
/100.0 14
/14 TLR8_HUMAN Toll-like receptor 8

4qbz[1] C alpha-D-mannopyranose-(2-3)-[beta-D-mannopyranose-.. A 100.0
/100.0 14
/14 TLR8_HUMAN Toll-like receptor 8

4r07[6] K alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(.. C 100.0
/100.0 13
/13 TLR8_HUMAN Toll-like receptor 8

5az5[5] M alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(.. C 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

5hdh[1] B alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(.. A 100.0
/100.0 13
/13 TLR8_HUMAN Toll-like receptor 8

5z14[1] F alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-.. B 100.0
/100.0 14
/14 TLR8_HUMAN Toll-like receptor 8

6v9u[1] H alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-.. B 100.0
/100.0 11
/11 TLR8_HUMAN Toll-like receptor 8

6zjz[1] C alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. A 100.0
/100.0 15
/15 TLR8_HUMAN Toll-like receptor 8

6zjz[1] E alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. A 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

7crf[1] C alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. A 100.0
/100.0 14
/14 TLR8_HUMAN Toll-like receptor 8

7crf[1] F alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. B 100.0
/100.0 14
/14 TLR8_HUMAN Toll-like receptor 8

7ytx[2] E alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. A 100.0
/100.0 11
/11 TLR8_HUMAN Toll-like receptor 8

7crf[1] H alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose.. B 100.0
/100.0 10
/10 TLR8_HUMAN Toll-like receptor 8

7ytx[1] C alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-.. A 100.0
/100.0 14
/14 TLR8_HUMAN Toll-like receptor 8

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

HOMO

1041 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

3w3g[69] B TLR8_HUMAN Toll-like receptor 8[743 aa] A 100.0
/100.0 26
/26 TLR8_HUMAN Toll-like receptor 8

3wn4[2] A TLR8_HUMAN Toll-like receptor 8[747 aa] A 100.0
/100.0 24
/24 TLR8_HUMAN Toll-like receptor 8

6zjz[10] B TLR8_HUMAN Toll-like receptor 8[740 aa] A 100.0
/100.0 32
/32 TLR8_HUMAN Toll-like receptor 8

6wml[1] C TLR8_HUMAN Toll-like receptor 8[681 aa] D 100.0
/100.0 43
/43 TLR8_HUMAN Toll-like receptor 8

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

PRECIPITANT

1041 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

3w3g[1] O BU3
(R,R)-2,3-BUTANEDIOL[6 atoms] A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

3w3j[2] AA SO4
SULFATE ION[5 atoms] A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

3w3j[1] N SO4
SULFATE ION[5 atoms] A 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

3w3j[5] O SO4
SULFATE ION[5 atoms] A 100.0
/100.0 2
/2 TLR8_HUMAN Toll-like receptor 8

3w3j[2] P SO4
SULFATE ION[5 atoms] A 100.0
/100.0 2
/2 TLR8_HUMAN Toll-like receptor 8

3w3j[1] Q SO4
SULFATE ION[5 atoms] A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

3w3j[2] R SO4
SULFATE ION[5 atoms] A 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

3w3j[6] S SO4
SULFATE ION[5 atoms] A 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

3w3j[2] T SO4
SULFATE ION[5 atoms] A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

3w3j[2] U SO4
SULFATE ION[5 atoms] A 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

3w3j[3] CA SO4
SULFATE ION[5 atoms] B 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

3w3j[1] GA SO4
SULFATE ION[5 atoms] B 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

3w3l[1] DA SO4
SULFATE ION[5 atoms] B 100.0
/100.0 1
/1 TLR8_HUMAN Toll-like receptor 8

5hdh[1] K SO4
SULFATE ION[5 atoms] A 100.0
/100.0 3
/3 TLR8_HUMAN Toll-like receptor 8

5hdh[1] L SO4
SULFATE ION[5 atoms] A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

5hdh[1] M SO4
SULFATE ION[5 atoms] A 100.0
/100.0 1
/1 TLR8_HUMAN Toll-like receptor 8

3w3j[1] IA GOL
GLYCEROL[6 atoms] B 100.0
/100.0 2
/2 TLR8_HUMAN Toll-like receptor 8

3w3n[1] P GOL
GLYCEROL[6 atoms] A 100.0
/100.0 6
/6 TLR8_HUMAN Toll-like receptor 8

5hdh[1] N MES
2-(N-MORPHOLINO)-ETHANESULFONIC ACID[12 atoms] A 100.0
/100.0 4
/4 TLR8_HUMAN Toll-like receptor 8

6zjz[1] T FMT
FORMIC ACID[3 atoms] B 100.0
/100.0 5
/5 TLR8_HUMAN Toll-like receptor 8

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

MONOMER
1041
	pdb_id	a¹	identity[%]²	description
	4qbz	A	100.0	TLR8_HUMAN Toll-like receptor 8
	1.a¹:asym_id for the homologue. 2.identity[%]²:sequence identity between the query and the homologue.

COMPOUND
1041	pdb_id	contact mol		homologue
	pdb_id	a³	description	a⁴	identity[%]⁵	Ncon⁶	description
	3w3g[54]	I	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	A	100.0 /100.0	4 /4	TLR8_HUMAN Toll-like receptor 8
	3w3g[73]	J	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	A	100.0 /100.0	2 /2	TLR8_HUMAN Toll-like receptor 8
	3w3g[37]	K	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	3w3g[71]	L	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	3w3g[52]	M	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	3w3n[6]	N	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	A	100.0 /100.0	4 /4	TLR8_HUMAN Toll-like receptor 8
	3w3n[16]	W	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	B	100.0 /100.0	4 /4	TLR8_HUMAN Toll-like receptor 8
	3w3n[28]	X	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	B	100.0 /100.0	4 /4	TLR8_HUMAN Toll-like receptor 8
	3wn4[2]	F	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	A	100.0 /100.0	7 /7	TLR8_HUMAN Toll-like receptor 8
	3wn4[2]	I	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	4qbz[13]	I	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	A	100.0 /100.0	4 /4	TLR8_HUMAN Toll-like receptor 8
	4qc0[4]	H	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	A	100.0 /100.0	10 /10	TLR8_HUMAN Toll-like receptor 8
	4r0a[3]	H	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	A	100.0 /100.0	4 /4	TLR8_HUMAN Toll-like receptor 8
	5awd[5]	G	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	5hdh[1]	E	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	A	100.0 /100.0	4 /4	TLR8_HUMAN Toll-like receptor 8
	5hdh[13]	H	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	A	100.0 /100.0	3 /3	TLR8_HUMAN Toll-like receptor 8
	5hdh[13]	J	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	A	100.0 /100.0	4 /4	TLR8_HUMAN Toll-like receptor 8
	6ty5[12]	J	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	A	100.0 /100.0	4 /4	TLR8_HUMAN Toll-like receptor 8
	6zjz[1]	L	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	A	100.0 /100.0	3 /3	TLR8_HUMAN Toll-like receptor 8
	7crf[2]	DA	NAG 2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms]..	A	100.0 /100.0	1 /1	TLR8_HUMAN Toll-like receptor 8
	3w3j[2]	M	C09 2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-4-amine..	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	3w3j[2]	V	C09 2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-4-amine..	A	100.0 /100.0	7 /7	TLR8_HUMAN Toll-like receptor 8
	3w3k[2]	I	L07 2-propyl[1,3]thiazolo[4,5-c]quinolin-4-amine[17 at..	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	3w3k[2]	M	L07 2-propyl[1,3]thiazolo[4,5-c]quinolin-4-amine[17 at..	A	100.0 /100.0	4 /4	TLR8_HUMAN Toll-like receptor 8
	3w3l[8]	JA	RX8 1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino..	A	100.0 /100.0	9 /9	TLR8_HUMAN Toll-like receptor 8
	3w3l[8]	KA	RX8 1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino..	A	100.0 /100.0	6 /6	TLR8_HUMAN Toll-like receptor 8
	3wn4[2]	E	D87 2-butylfuro[2,3-c]quinolin-4-amine[18 atoms]	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	4qbz[2]	O	D80 2-butyl[1,3]oxazolo[4,5-c]quinolin-4-amine[18 atom..	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	4qbz[2]	P	D80 2-butyl[1,3]oxazolo[4,5-c]quinolin-4-amine[18 atom..	A	100.0 /100.0	8 /8	TLR8_HUMAN Toll-like receptor 8
	4qc0[2]	J	XG1 2-butyl-2H-pyrazolo[3,4-c]quinolin-4-amine[18 atom..	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	4qc0[2]	K	XG1 2-butyl-2H-pyrazolo[3,4-c]quinolin-4-amine[18 atom..	A	100.0 /100.0	6 /6	TLR8_HUMAN Toll-like receptor 8
	4r07[14]	Q	URI URIDINE[17 atoms]	A	100.0 /100.0	7 /7	TLR8_HUMAN Toll-like receptor 8
	4r07[14]	X	URI URIDINE[17 atoms]	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	4r07[8]	R	UCG 3'-O-[(R)-{[(2R,3aR,4R,6R,6aR)-6-(2-amino-6-oxo-1,..	A	100.0 /100.0	15 /15	TLR8_HUMAN Toll-like receptor 8
	4r09[4]	Q	06S O-[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3,6-dihydro-9H-p..	A	100.0 /100.0	15 /15	TLR8_HUMAN Toll-like receptor 8
	4r09[4]	R	UPT 1-[(2R,3aR,4R,6R,6aR)-2-hydroxy-6-(hydroxymethyl)-..	A	100.0 /100.0	10 /10	TLR8_HUMAN Toll-like receptor 8
	4r09[4]	V	UPT 1-[(2R,3aR,4R,6R,6aR)-2-hydroxy-6-(hydroxymethyl)-..	A	100.0 /100.0	3 /3	TLR8_HUMAN Toll-like receptor 8
	4r6a[2]	M	HB2 1-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)..	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	4r6a[2]	N	HB2 1-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)..	A	100.0 /100.0	11 /11	TLR8_HUMAN Toll-like receptor 8
	5awa[2]	E	M8D 5-[[3-(aminomethyl)phenyl]methyl]-3-pentyl-quinoli..	A	100.0 /100.0	7 /7	TLR8_HUMAN Toll-like receptor 8
	5awa[2]	E	M8D 5-[[3-(aminomethyl)phenyl]methyl]-3-pentyl-quinoli..	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	5awb[2]	E	M0A 1-[[3-(aminomethyl)phenyl]methyl]-2-butyl-imidazo[..	A	100.0 /100.0	9 /9	TLR8_HUMAN Toll-like receptor 8
	5awb[2]	E	M0A 1-[[3-(aminomethyl)phenyl]methyl]-2-butyl-imidazo[..	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	5awc[4]	T	M4D 5-(4-azanylbutyl)-3-pentyl-quinolin-2-amine[21 ato..	A	100.0 /100.0	6 /6	TLR8_HUMAN Toll-like receptor 8
	5awc[4]	U	M4D 5-(4-azanylbutyl)-3-pentyl-quinolin-2-amine[21 ato..	A	100.0 /100.0	9 /9	TLR8_HUMAN Toll-like receptor 8
	5awd[2]	E	IDQ 1-[[4-(aminomethyl)phenyl]methyl]-2-butyl-imidazo[..	A	100.0 /100.0	9 /9	TLR8_HUMAN Toll-like receptor 8
	5awd[2]	E	IDQ 1-[[4-(aminomethyl)phenyl]methyl]-2-butyl-imidazo[..	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	5az5[4]	Q	MBL 1-pentyl-4-phenyl-imidazol-2-amine[17 atoms]	A	100.0 /100.0	7 /7	TLR8_HUMAN Toll-like receptor 8
	5az5[4]	U	MBL 1-pentyl-4-phenyl-imidazol-2-amine[17 atoms]	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	5wyx[2]	M	CU8 7-(3-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carb..	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	5wyx[2]	N	CU8 7-(3-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carb..	A	100.0 /100.0	11 /11	TLR8_HUMAN Toll-like receptor 8
	5wyz[2]	I	7VF 4-(3-methyl-4-oxidanyl-phenyl)quinolin-7-ol[19 ato..	A	100.0 /100.0	6 /6	TLR8_HUMAN Toll-like receptor 8
	5wyz[2]	M	7VF 4-(3-methyl-4-oxidanyl-phenyl)quinolin-7-ol[19 ato..	A	100.0 /100.0	11 /11	TLR8_HUMAN Toll-like receptor 8
	5z14[2]	I	7VC 4-(7-methoxyquinolin-4-yl)-2-methyl-phenol[20 atom..	A	100.0 /100.0	10 /10	TLR8_HUMAN Toll-like receptor 8
	5z14[2]	L	7VC 4-(7-methoxyquinolin-4-yl)-2-methyl-phenol[20 atom..	A	100.0 /100.0	6 /6	TLR8_HUMAN Toll-like receptor 8
	5z15[2]	I	7VL 4-(7-chloranylquinolin-4-yl)-2-methyl-phenol[19 at..	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	5z15[2]	N	7VL 4-(7-chloranylquinolin-4-yl)-2-methyl-phenol[19 at..	A	100.0 /100.0	9 /9	TLR8_HUMAN Toll-like receptor 8
	6kya[2]	I	DY3 3-[5-methylsulfanyl-4-(3,4,5-trimethylphenyl)-1,2,..	A	100.0 /100.0	10 /10	TLR8_HUMAN Toll-like receptor 8
	6kya[2]	N	DY3 3-[5-methylsulfanyl-4-(3,4,5-trimethylphenyl)-1,2,..	A	100.0 /100.0	7 /7	TLR8_HUMAN Toll-like receptor 8
	6ty5[1]	O	O0W 5-methyl-7-(7-methyl-2-piperidin-4-yl-indazol-5-yl..	B	100.0 /100.0	11 /11	TLR8_HUMAN Toll-like receptor 8
	6ty5[1]	V	O0W 5-methyl-7-(7-methyl-2-piperidin-4-yl-indazol-5-yl..	B	100.0 /100.0	8 /8	TLR8_HUMAN Toll-like receptor 8
	6v9u[2]	AA	QSM 2-(3,4-dimethoxyphenyl)-5-(piperidin-4-yl)-3-(prop..	A	100.0 /100.0	6 /6	TLR8_HUMAN Toll-like receptor 8
	6v9u[2]	R	QSM 2-(3,4-dimethoxyphenyl)-5-(piperidin-4-yl)-3-(prop..	A	100.0 /100.0	9 /9	TLR8_HUMAN Toll-like receptor 8
	6wml[4]	GA	U57 (2R)-2-[(2-amino-7-fluoropyrido[3,2-d]pyrimidin-4-..	A	100.0 /100.0	7 /7	TLR8_HUMAN Toll-like receptor 8
	6wml[4]	X	U57 (2R)-2-[(2-amino-7-fluoropyrido[3,2-d]pyrimidin-4-..	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	6wml[2]	Q	MAN alpha-D-mannopyranose[11 atoms]	A	100.0 /100.0	2 /2	TLR8_HUMAN Toll-like receptor 8
	6zjz[2]	N	QLH 5-[(3~{R},5~{S})-3-azanyl-5-(trifluoromethyl)piper..	A	100.0 /100.0	10 /10	TLR8_HUMAN Toll-like receptor 8
	6zjz[2]	S	QLH 5-[(3~{R},5~{S})-3-azanyl-5-(trifluoromethyl)piper..	A	100.0 /100.0	6 /6	TLR8_HUMAN Toll-like receptor 8
	7crf[2]	I	GD0 1-[2-(ethoxymethyl)-4-iodanyl-5-phenyl-imidazol-1-..	A	100.0 /100.0	7 /7	TLR8_HUMAN Toll-like receptor 8
	7crf[2]	U	GD0 1-[2-(ethoxymethyl)-4-iodanyl-5-phenyl-imidazol-1-..	A	100.0 /100.0	7 /7	TLR8_HUMAN Toll-like receptor 8
	7r52[2]	O	I6A 5-methoxy-6-pyridin-4-yl-1~{H}-indole[17 atoms]	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	7r52[2]	V	I6A 5-methoxy-6-pyridin-4-yl-1~{H}-indole[17 atoms]	A	100.0 /100.0	9 /9	TLR8_HUMAN Toll-like receptor 8
	7r53[2]	O	I5N 5-cyclopropyl-6-(2,6-dimethylpyridin-4-yl)-~{N}-[(..	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	7r53[2]	P	I5N 5-cyclopropyl-6-(2,6-dimethylpyridin-4-yl)-~{N}-[(..	A	100.0 /100.0	12 /12	TLR8_HUMAN Toll-like receptor 8
	7r54[2]	O	I5B (5-methoxy-6-pyridin-4-yl-1~{H}-indazol-3-yl)-(4-m..	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	7r54[2]	P	I5B (5-methoxy-6-pyridin-4-yl-1~{H}-indazol-3-yl)-(4-m..	A	100.0 /100.0	9 /9	TLR8_HUMAN Toll-like receptor 8
	7rc9[2]	P	RQY 2-(2,6-dimethylpyridin-4-yl)-5-(piperidin-4-yl)-3-..	A	100.0 /100.0	10 /10	TLR8_HUMAN Toll-like receptor 8
	7rc9[2]	X	RQY 2-(2,6-dimethylpyridin-4-yl)-5-(piperidin-4-yl)-3-..	A	100.0 /100.0	6 /6	TLR8_HUMAN Toll-like receptor 8
	7ytx[2]	I	JRI (2R,6R)-4-(8-cyanoquinolin-5-yl)-N-[(3S,4R)-4-fluo..	A	100.0 /100.0	12 /12	TLR8_HUMAN Toll-like receptor 8
	7ytx[2]	S	JRI (2R,6R)-4-(8-cyanoquinolin-5-yl)-N-[(3S,4R)-4-fluo..	A	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	8pfi[2]	O	YHG (3~{S})-~{N}-[4-[[5-(1,6-dimethylpyrazolo[3,4-b]py..	A	100.0 /100.0	13 /13	TLR8_HUMAN Toll-like receptor 8
	8pfi[2]	P	YHG (3~{S})-~{N}-[4-[[5-(1,6-dimethylpyrazolo[3,4-b]py..	A	100.0 /100.0	6 /6	TLR8_HUMAN Toll-like receptor 8
	3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
OTHERPOLY
1041	pdb_id	contact mol		homologue
	pdb_id	a³	description	a⁴	identity[%]⁵	Ncon⁶	description
	3w3g[20]	C	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..	A	100.0 /100.0	13 /13	TLR8_HUMAN Toll-like receptor 8
	3w3g[23]	D	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..	A	100.0 /100.0	12 /12	TLR8_HUMAN Toll-like receptor 8
	3w3g[37]	E	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..	A	100.0 /100.0	11 /11	TLR8_HUMAN Toll-like receptor 8
	3w3n[3]	G	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..	A	100.0 /100.0	1 /1	TLR8_HUMAN Toll-like receptor 8
	6ty5[12]	D	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..	A	100.0 /100.0	10 /10	TLR8_HUMAN Toll-like receptor 8
	3w3g[1]	F	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..	B	100.0 /100.0	13 /13	TLR8_HUMAN Toll-like receptor 8
	3w3j[43]	D	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..	A	100.0 /100.0	10 /10	TLR8_HUMAN Toll-like receptor 8
	3w3j[12]	D	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..	B	100.0 /100.0	1 /1	TLR8_HUMAN Toll-like receptor 8
	4r09[4]	G	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..	A	100.0 /100.0	9 /9	TLR8_HUMAN Toll-like receptor 8
	5hdh[1]	C	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..	A	100.0 /100.0	7 /7	TLR8_HUMAN Toll-like receptor 8
	3w3j[16]	C	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..	A	100.0 /100.0	14 /14	TLR8_HUMAN Toll-like receptor 8
	5az5[2]	G	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..	A	100.0 /100.0	10 /10	TLR8_HUMAN Toll-like receptor 8
	7crf[2]	G	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..	B	100.0 /100.0	8 /8	TLR8_HUMAN Toll-like receptor 8
	3w3k[20]	C	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..	A	100.0 /100.0	13 /13	TLR8_HUMAN Toll-like receptor 8
	3w3k[20]	E	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..	A	100.0 /100.0	9 /9	TLR8_HUMAN Toll-like receptor 8
	5hdh[12]	D	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..	A	100.0 /100.0	8 /8	TLR8_HUMAN Toll-like receptor 8
	6ty5[11]	C	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..	A	100.0 /100.0	14 /14	TLR8_HUMAN Toll-like receptor 8
	3wn4[4]	B	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..	A	100.0 /100.0	14 /14	TLR8_HUMAN Toll-like receptor 8
	4qbz[1]	C	alpha-D-mannopyranose-(2-3)-[beta-D-mannopyranose-..	A	100.0 /100.0	14 /14	TLR8_HUMAN Toll-like receptor 8
	4r07[6]	K	alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..	C	100.0 /100.0	13 /13	TLR8_HUMAN Toll-like receptor 8
	5az5[5]	M	alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..	C	100.0 /100.0	10 /10	TLR8_HUMAN Toll-like receptor 8
	5hdh[1]	B	alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..	A	100.0 /100.0	13 /13	TLR8_HUMAN Toll-like receptor 8
	5z14[1]	F	alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-..	B	100.0 /100.0	14 /14	TLR8_HUMAN Toll-like receptor 8
	6v9u[1]	H	alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-..	B	100.0 /100.0	11 /11	TLR8_HUMAN Toll-like receptor 8
	6zjz[1]	C	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-..	A	100.0 /100.0	15 /15	TLR8_HUMAN Toll-like receptor 8
	6zjz[1]	E	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-..	A	100.0 /100.0	10 /10	TLR8_HUMAN Toll-like receptor 8
	7crf[1]	C	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-..	A	100.0 /100.0	14 /14	TLR8_HUMAN Toll-like receptor 8
	7crf[1]	F	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-..	B	100.0 /100.0	14 /14	TLR8_HUMAN Toll-like receptor 8
	7ytx[2]	E	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-..	A	100.0 /100.0	11 /11	TLR8_HUMAN Toll-like receptor 8
	7crf[1]	H	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..	B	100.0 /100.0	10 /10	TLR8_HUMAN Toll-like receptor 8
	7ytx[1]	C	alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-..	A	100.0 /100.0	14 /14	TLR8_HUMAN Toll-like receptor 8
	3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
HOMO
1041	pdb_id	contact mol		homologue
	pdb_id	a³	description	a⁴	identity[%]⁵	Ncon⁶	description
	3w3g[69]	B	TLR8_HUMAN Toll-like receptor 8[743 aa]	A	100.0 /100.0	26 /26	TLR8_HUMAN Toll-like receptor 8
	3wn4[2]	A	TLR8_HUMAN Toll-like receptor 8[747 aa]	A	100.0 /100.0	24 /24	TLR8_HUMAN Toll-like receptor 8
	6zjz[10]	B	TLR8_HUMAN Toll-like receptor 8[740 aa]	A	100.0 /100.0	32 /32	TLR8_HUMAN Toll-like receptor 8
	6wml[1]	C	TLR8_HUMAN Toll-like receptor 8[681 aa]	D	100.0 /100.0	43 /43	TLR8_HUMAN Toll-like receptor 8
	3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
PRECIPITANT
1041	pdb_id	contact mol		homologue
	pdb_id	a³	description	a⁴	identity[%]⁵	Ncon⁶	description
	3w3g[1]	O	BU3 (R,R)-2,3-BUTANEDIOL[6 atoms]	A	100.0 /100.0	6 /6	TLR8_HUMAN Toll-like receptor 8
	3w3j[2]	AA	SO4 SULFATE ION[5 atoms]	A	100.0 /100.0	4 /4	TLR8_HUMAN Toll-like receptor 8
	3w3j[1]	N	SO4 SULFATE ION[5 atoms]	A	100.0 /100.0	3 /3	TLR8_HUMAN Toll-like receptor 8
	3w3j[5]	O	SO4 SULFATE ION[5 atoms]	A	100.0 /100.0	2 /2	TLR8_HUMAN Toll-like receptor 8
	3w3j[2]	P	SO4 SULFATE ION[5 atoms]	A	100.0 /100.0	2 /2	TLR8_HUMAN Toll-like receptor 8
	3w3j[1]	Q	SO4 SULFATE ION[5 atoms]	A	100.0 /100.0	6 /6	TLR8_HUMAN Toll-like receptor 8
	3w3j[2]	R	SO4 SULFATE ION[5 atoms]	A	100.0 /100.0	3 /3	TLR8_HUMAN Toll-like receptor 8
	3w3j[6]	S	SO4 SULFATE ION[5 atoms]	A	100.0 /100.0	3 /3	TLR8_HUMAN Toll-like receptor 8
	3w3j[2]	T	SO4 SULFATE ION[5 atoms]	A	100.0 /100.0	6 /6	TLR8_HUMAN Toll-like receptor 8
	3w3j[2]	U	SO4 SULFATE ION[5 atoms]	A	100.0 /100.0	3 /3	TLR8_HUMAN Toll-like receptor 8
	3w3j[3]	CA	SO4 SULFATE ION[5 atoms]	B	100.0 /100.0	3 /3	TLR8_HUMAN Toll-like receptor 8
	3w3j[1]	GA	SO4 SULFATE ION[5 atoms]	B	100.0 /100.0	3 /3	TLR8_HUMAN Toll-like receptor 8
	3w3l[1]	DA	SO4 SULFATE ION[5 atoms]	B	100.0 /100.0	1 /1	TLR8_HUMAN Toll-like receptor 8
	5hdh[1]	K	SO4 SULFATE ION[5 atoms]	A	100.0 /100.0	3 /3	TLR8_HUMAN Toll-like receptor 8
	5hdh[1]	L	SO4 SULFATE ION[5 atoms]	A	100.0 /100.0	4 /4	TLR8_HUMAN Toll-like receptor 8
	5hdh[1]	M	SO4 SULFATE ION[5 atoms]	A	100.0 /100.0	1 /1	TLR8_HUMAN Toll-like receptor 8
	3w3j[1]	IA	GOL GLYCEROL[6 atoms]	B	100.0 /100.0	2 /2	TLR8_HUMAN Toll-like receptor 8
	3w3n[1]	P	GOL GLYCEROL[6 atoms]	A	100.0 /100.0	6 /6	TLR8_HUMAN Toll-like receptor 8
	5hdh[1]	N	MES 2-(N-MORPHOLINO)-ETHANESULFONIC ACID[12 atoms]	A	100.0 /100.0	4 /4	TLR8_HUMAN Toll-like receptor 8
	6zjz[1]	T	FMT FORMIC ACID[3 atoms]	B	100.0 /100.0	5 /5	TLR8_HUMAN Toll-like receptor 8
	3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

Contact Molecules for Homologous Proteins

Summary Bars[70 %]

UniProt Feature Tables [Q9NR97(TLR8_HUMAN)]