Contact Molecules for Homologous Proteins


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PID QueryLength Homolgous Sequence in PDB UniProt Query TITLE
2900190 1817 155 P52948(NUP98_HUMAN) RecName: Full=Nuclear pore complex protein Nup98-Nup96 ; EC=3.4.21.- ;Contains: RecName: Full=Nuclear pore complex protein Nup98; AltName: Full=98 kDa nucleoporin; AltName: Full=Nucleoporin Nup98; Short=Nup98;Contains: RecName: Full=Nuclear pore complex protein Nup96; AltName: Full=96 kDa nucleoporin; AltName: Full=Nucleoporin Nup96; Short=Nup96;Flags: Precursor;
QUERYSEQ
MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGP
SSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF
SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFG
NNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKL
VLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYTNPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDREEIENNSYHMHPAGIILTKVGYYTIPSMDDL
AKITNEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDIVHIRRKEVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTS
TKKLKTAPLPPASQTTPLQMALNGKPAPPPQSQSPEVEQLGRVVELDSDMVDITQEPVLDTMLEESMPEDQEPVSASTHIASSLGINPHVLQIMKASLLTDEEDVDMALDQRFSRLPSKADTSQEICSPRLPISASHSSKTRSLVGGLLQ
SKFTSGAFLSPSVSVQECRTPRAASLMNIPSTSSWSVPPPLTSVFTMPSPAPEVPLKTVGTRRQLGLVPREKSVTYGKGKLLMDMALFMGRSFRVGWGPNWTLANSGEQLNGSHELENHQIADSMEFGFLPNPVAVKPLTESPFKVHLEK
LSLRQRKPDEDMKLYQTPLELKLKHSTVHVDELCPLIVPNLGVAVIHDYADWVKEASGDLPEAQIVKHWSLTWTLCEALWGHLKELDSQLNEPREYIQILERRRAFSRWLSCTATPQIEEEVSLTQKNSPVEAVFSYLTGKRISEACSLA
QQSGDHRLALLLSQFVGSQSVRELLTMQLVDWHQLQADSFIQDERLRIFALLAGKPVWQLSEKKQINVCSQLDWKRSLAIHLWYLLPPTASISRALSMYEEAFQNTSDSDRYACSPLPSYLEGSGCVIAEEQNSQTPLRDVCFHLLKLYS
DRHYDLNQLLEPRSITADPLDYRLSWHLWEVLRALNYTHLSAQCEGVLQASYAGQLESEGLWEWAIFVLLHIDNSGIREKAVRELLTRHCQLLETPESWAKETFLTQKLRVPAKWIHEAKAVRAHMESDKHLEALCLFKAEHWNRCHKLI
IRHLASDAIINENYDYLKGFLEDLAPPERSSLIQDWETSGLVYLDYIRVIEMLRHIQQVDCSGNDLEQLHIKVTSLCSRIEQIQCYSAKDRLAQSDMAKRVANLLRVVLSLHHPPDRTSDSTPDPQRVPLRLLAPHIGRLPMPEDYAMDE
LRSLTQSYLRELAVGSL
[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]

UniProt Feature Tables [P52948(NUP98_HUMAN)]

1817
region name description
1-880 CHAIN /note="Nuclear pore complex protein Nup98" /id="PRO_0000019929"
881-1817 CHAIN /note="Nuclear pore complex protein Nup96" /id="PRO_0000019930"
738-880 DOMAIN /note="Peptidase S59"
1-156 REGION /note="FG repeats 1"
157-213 REGION /note="GLEBS; interaction with RAE1"
214-480 REGION /note="FG repeats 2"
512-535 REGION /note="Disordered"
614-633 REGION /note="Disordered"
662-682 REGION /note="Disordered"
886-937 REGION /note="Disordered"
886-901 COMPBIAS /note="Basic and acidic residues"
902-921 COMPBIAS /note="Polar residues"
881-881 ACT_SITE /note="Nucleophile" ECO:0000269|PubMed:18287282"
1-1817 DISORDER predicted by DISOPRED

MONOMER
1817
pdb_id a1 identity[%]2 description
7r5k MB 100.0 NUP98_HUMAN Nuclear pore complex protein Nup96
2q5y A 100.0 NUP98_HUMAN Nuclear pore complex protein Nup98
7byf F 100.0 Q3TPG3_MOUSE Peptidase S59 domain-containing protein
7q64 CA 100.0 NUP98_HUMAN Nuclear pore complex protein Nup98
8ci8 X 100.0 NUP98_HUMAN Nuclear pore complex protein Nup98
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue.
HETERO
1817 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1ko6[2] B NU98_HUMAN Nuclear Pore Complex Protein Nup98[6 aa] A 100.0
/100.0
11
/11
NUP98_HUMAN Nuclear Pore Complex Protein Nup98
1ko6[1] B NU98_HUMAN Nuclear Pore Complex Protein Nup98[6 aa] C 100.0
/100.0
1
/1
NUP98_HUMAN Nuclear Pore Complex Protein Nup98
2q5y[2] B NUP98_HUMAN Nuclear pore complex protein Nup96[3 aa] A 100.0
/100.0
11
/11
NUP98_HUMAN Nuclear pore complex protein Nup98
3mmy[15] A RAE1L_HUMAN mRNA export factor[354 aa] B 100.0
/100.0
29
/29
NUP98_HUMAN Nuclear pore complex protein Nup98
7f60[4] B RAE1L_HUMAN mRNA export factor[330 aa] C 100.0
/100.0
25
/25
NUP98_HUMAN Nuclear pore complex protein Nup98-Nup96
4owr[1] C MATRX_VSIVS Matrix protein[176 aa] B 100.0
/100.0
3
/3
NUP98_HUMAN Nuclear pore complex protein Nup98-Nup96
5a9q[32] E NU107_HUMAN NUCLEAR PORE COMPLEX PROTEIN NUP107[660 aa] F 100.0
/100.0
7
/7
NUP98_HUMAN NUCLEAR PORE COMPLEX PROTEIN NUP96
5a9q[32] G SEC13_HUMAN PROTEIN SEC13 HOMOLOG[285 aa] F 100.0
/100.0
8
/8
NUP98_HUMAN NUCLEAR PORE COMPLEX PROTEIN NUP96
7peq[32] D SEC13_HUMAN Protein SEC13 homolog[285 aa] C 100.0
/100.0
13
/13
NUP98_HUMAN Nuclear pore complex protein Nup96
7r5j[64] OB SEC13_HUMAN Protein SEC13 homolog[301 aa] KB 100.0
/100.0
59
/59
NUP98_HUMAN Nuclear pore complex protein Nup96
7byf[2] D O41931_MHV68 10 protein[399 aa] B 100.0
/100.0
2
/2
Q3TPG3_MOUSE Peptidase S59 domain-containing protein
7mni[2] A NUP88_HUMAN Nuclear pore complex protein Nup88[409 aa] B 100.0
/100.0
27
/27
NUP98-2_HUMAN Nuclear pore complex protein Nup98
7peq[24] B NU107_HUMAN Nuclear pore complex protein Nup107[678 aa] C 100.0
/100.0
4
/4
NUP98_HUMAN Nuclear pore complex protein Nup96
7peq[8] F NUP85_HUMAN Nuclear pore complex protein Nup85[632 aa] C 100.0
/100.0
1
/1
NUP98_HUMAN Nuclear pore complex protein Nup96
7r5j[32] WB NUP85_HUMAN Nuclear pore complex protein Nup85[655 aa] LB 100.0
/100.0
2
/2
NUP98_HUMAN Nuclear pore complex protein Nup96
7peq[32] H NU160_HUMAN Nuclear pore complex protein Nup160[996 aa] C 100.0
/100.0
32
/32
NUP98_HUMAN Nuclear pore complex protein Nup96
7r5j[24] A RBP2_HUMAN E3 SUMO-protein ligase RanBP2[756 aa] KB 100.0
/100.0
1
/1
NUP98_HUMAN Nuclear pore complex protein Nup96
7r5j[16] C RBP2_HUMAN E3 SUMO-protein ligase RanBP2[756 aa] KB 100.0
/100.0
3
/3
NUP98_HUMAN Nuclear pore complex protein Nup96
7r5j[8] D RBP2_HUMAN E3 SUMO-protein ligase RanBP2[756 aa] LB 100.0
/100.0
5
/5
NUP98_HUMAN Nuclear pore complex protein Nup96
7r5k[8] B RBP2_HUMAN E3 SUMO-protein ligase RanBP2[756 aa] KB 100.0
/100.0
7
/7
NUP98_HUMAN Nuclear pore complex protein Nup96
7r5k[8] D RBP2_HUMAN E3 SUMO-protein ligase RanBP2[756 aa] LB 100.0
/100.0
4
/4
NUP98_HUMAN Nuclear pore complex protein Nup96
7r5j[64] EC NU160_HUMAN Nuclear pore complex protein Nup160[1399 aa] KB 100.0
/100.0
30
/30
NUP98_HUMAN Nuclear pore complex protein Nup96
7r5j[64] GB NU107_HUMAN Nuclear pore complex protein Nup107[782 aa] KB 100.0
/100.0
22
/22
NUP98_HUMAN Nuclear pore complex protein Nup96
7r5j[32] HB NU107_HUMAN Nuclear pore complex protein Nup107[782 aa] KB 100.0
/100.0
4
/4
NUP98_HUMAN Nuclear pore complex protein Nup96
7r5j[24] U NUP93_HUMAN Nuclear pore complex protein Nup93[726 aa] KB 100.0
/100.0
15
/15
NUP98_HUMAN Nuclear pore complex protein Nup96
7r5j[8] V NUP93_HUMAN Nuclear pore complex protein Nup93[726 aa] MB 100.0
/100.0
4
/4
NUP98_HUMAN Nuclear pore complex protein Nup96
7vpg[2] K NS6_SARS ORF6 protein[10 aa] F 100.0
/100.0
1
/1
NUP98_HUMAN Isoform 3 of Nuclear pore complex protein Nup98-Nu..
7vph[1] L NS6_SARS2 ORF6 protein[9 aa] B 100.0
/100.0
1
/1
NUP98_HUMAN Isoform 3 of Nuclear pore complex protein Nup98-Nu..
3tkn[3] A NUP82_YEAST Nucleoporin NUP82[451 aa] C 95.2
/98.0
21
/21
Q6PFD9_MOUSE Nucleoporin 98
7now[2] A Anti-Nup98 nanobody MS98-27[129 aa] B 88.9
/72.8
18
/18
A0A6I8SCP2_XENTR Nuclear pore complex protein Nup98
7nqa[2] B Anti-Nup98 Nanobody MS98-6[124 aa] A 68.2
/72.8
22
/22
A0A6I8SCP2_XENTR Nuclear pore complex protein Nup98-Nup96
5e0q[1] A Anti-Nup98 Nanobody TP377[126 aa] B 78.9
/72.2
19
/19
J7I6Y1_XENTR Nuclear pore complex protein Nup98-Nup96
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
METAL
1817 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
7now[2] E NA
SODIUM ION[1 atoms]
B 75.0
/72.8
4
/4
A0A6I8SCP2_XENTR Nuclear pore complex protein Nup98
7now[2] H NA
SODIUM ION[1 atoms]
D 100.0
/72.8
4
/4
A0A6I8SCP2_XENTR Nuclear pore complex protein Nup98
7nq6[1] C NA
SODIUM ION[1 atoms]
A 80.0
/72.8
5
/5
F6ZMG3_XENTR Nuclear pore complex protein Nup96
7nq6[1] E NA
SODIUM ION[1 atoms]
A 0.0
/72.8
1
/1
F6ZMG3_XENTR Nuclear pore complex protein Nup96
7nqa[1] G NA
SODIUM ION[1 atoms]
C 100.0
/72.8
1
/1
A0A6I8SCP2_XENTR Nuclear pore complex protein Nup98-Nup96
7nq6[1] F CL
CHLORIDE ION[1 atoms]
A 50.0
/72.8
2
/2
F6ZMG3_XENTR Nuclear pore complex protein Nup96
7nq6[1] G CL
CHLORIDE ION[1 atoms]
A 100.0
/72.8
1
/1
F6ZMG3_XENTR Nuclear pore complex protein Nup96
7nq6[1] H CL
CHLORIDE ION[1 atoms]
A 100.0
/72.8
4
/4
F6ZMG3_XENTR Nuclear pore complex protein Nup96
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
HOMO
1817 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1ko6[1] C NUP98_HUMAN Nuclear Pore Complex Protein Nup98[148 aa] A 100.0
/100.0
12
/12
NUP98_HUMAN Nuclear Pore Complex Protein Nup98
1ko6[1] A NUP98_HUMAN Nuclear Pore Complex Protein Nup98[152 aa] C 100.0
/100.0
16
/16
NUP98_HUMAN Nuclear Pore Complex Protein Nup98
7peq[8] L NUP98_HUMAN Nuclear pore complex protein Nup96[543 aa] C 100.0
/100.0
1
/1
NUP98_HUMAN Nuclear pore complex protein Nup96
7peq[8] C NUP98_HUMAN Nuclear pore complex protein Nup96[543 aa] L 100.0
/100.0
3
/3
NUP98_HUMAN Nuclear pore complex protein Nup96
7q64[576] G NUP98_HUMAN Nuclear pore complex protein Nup98[34 aa] A 100.0
/100.0
2
/2
NUP98_HUMAN Nuclear pore complex protein Nup98
7q66[21] B NUP98_HUMAN Nuclear pore complex protein Nup98[25 aa] A 100.0
/100.0
6
/6
NUP98_HUMAN Nuclear pore complex protein Nup98
7q66[20] D NUP98_HUMAN Nuclear pore complex protein Nup98[25 aa] B 100.0
/100.0
25
/25
NUP98_HUMAN Nuclear pore complex protein Nup98
7q66[19] B NUP98_HUMAN Nuclear pore complex protein Nup98[25 aa] C 100.0
/100.0
1
/1
NUP98_HUMAN Nuclear pore complex protein Nup98
8ci8[9] A NUP98_HUMAN Nuclear pore complex protein Nup98[10 aa] B 100.0
/100.0
6
/6
NUP98_HUMAN Nuclear pore complex protein Nup98
8ci8[84] C NUP98_HUMAN Nuclear pore complex protein Nup98[26 aa] B 100.0
/100.0
13
/13
NUP98_HUMAN Nuclear pore complex protein Nup98
8ci8[13] E NUP98_HUMAN Nuclear pore complex protein Nup98[10 aa] D 100.0
/100.0
9
/9
NUP98_HUMAN Nuclear pore complex protein Nup98
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
PRECIPITANT
1817 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
7now[2] F SO4
SULFATE ION[5 atoms]
B 66.7
/72.8
3
/3
A0A6I8SCP2_XENTR Nuclear pore complex protein Nup98
7nq6[1] B MPD
(4S)-2-METHYL-2,4-PENTANEDIOL[8 atoms]
A 66.7
/72.8
3
/3
F6ZMG3_XENTR Nuclear pore complex protein Nup96
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.