Contact Molecules for Homologous Proteins | ||||
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PID | QueryLength | Homolgous Sequence in PDB | UniProt Query | TITLE |
2622207 | 358 | 63 | P13747(HLAE_HUMAN) | RecName: Full=HLA class I histocompatibility antigen, alpha chain E;AltName: Full=MHC class I antigen E;Contains: RecName: Full=Soluble HLA class I histocompatibility antigen, alpha chain E; Short=sHLA-E ;Flags: Precursor; |
QUERYSEQ |
MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCELGPDGRFLRGYEQFAYDGKDYLTLNED LRSWTAVDTAAQISEQKSNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAEWSDSAQGSESHSL |
358 |
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region | name | description |
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1-21 | SIGNAL | |
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22-358 | CHAIN | /note="HLA class I histocompatibility antigen, alpha chain E" /id="PRO_0000018882" |
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22-0 | CHAIN | /note="Soluble HLA class I histocompatibility antigen, alpha chain E" /id="PRO_0000445757" |
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22-305 | TOPO_DOM | /note="Extracellular" |
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306-329 | TRANSMEM | /note="Helical" |
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330-358 | TOPO_DOM | /note="Cytoplasmic" |
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206-294 | DOMAIN | /note="Ig-like C1-type" |
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22-111 | REGION | /note="Alpha-1" |
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112-203 | REGION | /note="Alpha-2" |
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204-295 | REGION | /note="Alpha-3" |
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296-305 | REGION | /note="Connecting peptide" |
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333-358 | REGION | /note="Disordered" |
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344-358 | COMPBIAS | /note="Polar residues" |
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28-28 | BINDING | /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="1" /ligand_note="pathogen-derived peptide antigen" ECO:0000269|PubMed:35705051, ECO:0007744|PDB:7P4B" |
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84-84 | BINDING | /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="1" /ligand_note="pathogen-derived peptide antigen" ECO:0007744|PDB:7P49, ECO:0007744|PDB:7P4B" |
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87-87 | BINDING | /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="1" /ligand_note="pathogen-derived peptide antigen" ECO:0007744|PDB:7P4B" |
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98-98 | BINDING | /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="1" /ligand_note="pathogen-derived peptide antigen" ECO:0007744|PDB:7P49, ECO:0007744|PDB:7P4B" |
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98-98 | BINDING | /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="2" /ligand_note="self-peptide antigen" |
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105-105 | BINDING | /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="1" /ligand_note="pathogen-derived peptide antigen" ECO:0007744|PDB:7P49, ECO:0007744|PDB:7P4B" |
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105-105 | BINDING | /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="2" /ligand_note="self-peptide antigen" |
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164-164 | BINDING | /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="1" /ligand_note="pathogen-derived peptide antigen" ECO:0000269|PubMed:35705051, ECO:0007744|PDB:7P49, ECO:0007744|PDB:7P4B" |
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164-164 | BINDING | /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="2" /ligand_note="self-peptide antigen" |
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167-167 | BINDING | /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="1" /ligand_note="pathogen-derived peptide antigen" ECO:0000269|PubMed:35705051, ECO:0007744|PDB:7P49, ECO:0007744|PDB:7P4B" |
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167-167 | BINDING | /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="2" /ligand_note="self-peptide antigen" |
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177-177 | BINDING | /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="2" /ligand_note="self-peptide antigen" |
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180-180 | BINDING | /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="1" /ligand_note="pathogen-derived peptide antigen" ECO:0000269|PubMed:35705051, ECO:0007744|PDB:7P49, ECO:0007744|PDB:7P4B" |
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180-180 | BINDING | /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="2" /ligand_note="self-peptide antigen" |
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192-192 | BINDING | /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="1" /ligand_note="pathogen-derived peptide antigen" ECO:0000269|PubMed:35705051, ECO:0007744|PDB:7P49" |
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192-192 | BINDING | /ligand="a peptide antigen" /ligand_id="ChEBI:CHEBI:166823" /ligand_label="2" /ligand_note="self-peptide antigen" |
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1-358 | DISORDER | predicted by DISOPRED |
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358 | |||||||
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pdb_id | a1 | identity[%]2 | description | |||
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C | 100.0 | HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E | |||
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue. |
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358 | pdb_id | contact mol | homologue | ||||
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a3 | description | a4 | identity[%]5 | Ncon6 | description | |
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B | B2MG_HUMAN BETA-2-MICROGLOBULIN[100 aa] | A | 100.0 /99.6 |
34 /34 |
HLAE_HUMAN HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAI.. |
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B | B2MG_HUMAN BETA-2-MICROGLOBULIN[100 aa] | A | 100.0 /99.6 |
2 /2 |
HLAE_HUMAN HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAI.. |
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B | B2MG_HUMAN BETA-2-MICROGLOBULIN[100 aa] | C | 100.0 /99.6 |
3 /3 |
HLAE_HUMAN HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAI.. |
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D | B2MG_HUMAN Beta-2-microglobulin[98 aa] | A | 100.0 /100.0 |
1 /1 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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E | Peptide VMAPRTVLL[9 aa] | A | 100.0 /99.6 |
29 /29 |
HLAE_HUMAN HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAI.. |
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F | Peptide VMAPRTVLL[9 aa] | A | 100.0 /99.6 |
3 /3 |
HLAE_HUMAN HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAI.. |
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E | Mtb44*P2-Phe peptide variant (ARG-PHE-PRO-ALA-LYS-.. | A | 100.0 /100.0 |
30 /30 |
E2G051_HUMAN MHC class I antigen |
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C | INHA_MYCTU Enoyl-[acyl-carrier-protein] reductase [NADH][9 aa.. | A | 100.0 /100.0 |
22 /22 |
E2G051_HUMAN MHC class I antigen |
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I | ARG-GLN-PRO-ALA-LYS-ALA-PRO-LEU-LEU[9 aa] | A | 100.0 /100.0 |
26 /26 |
E2G051_HUMAN MHC class I antigen |
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E | ARG-LEU-PRO-ALA-LYS-ALA-PRO-LEU-PHE[9 aa] | A | 100.0 /100.0 |
23 /23 |
Q59EE1_HUMAN HLA class I histocompatibility antigen, E alpha ch.. |
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I | ARG-MET-TYR-SER-PRO-THR-SER-ILE-LEU[9 aa] | A | 100.0 /100.0 |
27 /27 |
E2G051_HUMAN MHC class I antigen |
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E | 3H4 Fab heavy chain[225 aa] | A | 100.0 /100.0 |
11 /11 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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F | 3H4 Fab light chain[214 aa] | A | 100.0 /100.0 |
5 /5 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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C | B6S6I4_9HIV1 Gag6V[9 aa] | A | 100.0 /100.0 |
25 /25 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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E | TVB79_HUMAN TJB12_HUMAN K7N5M4_HUMAN T cell receptor beta variable 7-9,M1-specific T ce.. | A | 100.0 /100.0 |
8 /8 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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I | PPSB_MYCTU Phenolphthiocerol/phthiocerol polyketide synthase .. | A | 100.0 /100.0 |
26 /26 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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I | ESXH_MYCTU ESAT-6-like protein EsxH[9 aa] | A | 100.0 /100.0 |
22 /22 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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D | T-cell receptor alpha chain[187 aa] | A | 100.0 /100.0 |
10 /10 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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E | Q0QI92_HCMV Peptide from Glycoprotein[9 aa] | A | 100.0 /99.6 |
28 /28 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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C | 1C07_HUMAN leader peptide of HLA class I histocompatibility a.. | A | 100.0 /99.6 |
31 /31 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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D | TVA4_HUMAN A0A075B6U7_HUMAN TRAR1_HUMAN TCR Gag:02-alpha,TCR Gag:02-alpha,TCR Gag:02-alpha.. | A | 100.0 /100.0 |
9 /9 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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C | Gag6V(276-284 H4C)[9 aa] | A | 96.2 /99.6 |
26 /26 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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E | Peptide VTAPRTLLL[9 aa] | A | 100.0 /99.6 |
30 /30 |
HLAE_HUMAN HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAI.. |
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F | Peptide VTAPRTLLL[9 aa] | A | 100.0 /99.6 |
2 /2 |
HLAE_HUMAN HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAI.. |
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C | INHA_MYCTU Enoyl-[acyl-carrier-protein] reductase [NADH][12 a.. | A | 97.1 /99.6 |
34 /34 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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I | HLAG_HUMAN leader peptide of HLA class I histocompatibility a.. | A | 100.0 /99.6 |
30 /30 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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C | KLRD1_HUMAN Natural killer cells antigen CD94[123 aa] | A | 100.0 /99.6 |
10 /10 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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D | NKG2A_HUMAN NKG2-A/NKG2-B type II integral membrane protein[11.. | A | 100.0 /99.6 |
8 /8 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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C | VMAPRTLIL peptide from CMV gpUL40[9 aa] | A | 100.0 /99.6 |
29 /29 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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C | VMAPRTLIL peptide from CMV gpUL40[9 aa] | A | 100.0 /99.6 |
27 /27 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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D | GF4 T cell receptor alpha chain[201 aa] | A | 100.0 /99.6 |
8 /8 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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E | GF4 T cell receptor beta chain[243 aa] | A | 100.0 /99.6 |
9 /9 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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C | leader peptide of HLA class I histocompatibility a.. | A | 100.0 /99.6 |
28 /28 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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D | T-cell receptor alpha chain[188 aa] | A | 100.0 /100.0 |
7 /7 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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D | T-cell receptor alpha chain[190 aa] | A | 100.0 /99.6 |
7 /7 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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E | T-cell receptor beta chain[243 aa] | A | 100.0 /100.0 |
9 /9 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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E | T-cell receptor beta chain[245 aa] | A | 100.0 /99.6 |
12 /12 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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C | INHA_MYCTU Enoyl-[acyl-carrier-protein] reductase [NADH][9 aa.. | A | 96.2 /99.6 |
26 /26 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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D | TCA_HUMAN KK50.4 T cell receptor alpha chain[199 aa] | A | 100.0 /99.6 |
7 /7 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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D | TVAZ1_HUMAN A0A087X096_HUMAN TRAC_HUMAN T cell receptor alpha variable 26-1,T cell recepto.. | A | 100.0 /99.6 |
5 /5 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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E | TCB_HUMAN KK50.4 T cell receptor beta chain[240 aa] | A | 100.0 /99.6 |
12 /12 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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E | TVB14_HUMAN TJB23_HUMAN TRBC2_HUMAN T cell receptor beta variable 14,T cell receptor b.. | A | 100.0 /99.6 |
11 /11 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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J | TVB14_HUMAN TJB23_HUMAN TRBC2_HUMAN T cell receptor beta variable 14,T cell receptor b.. | A | 100.0 /99.6 |
7 /7 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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C | UL40(15-23 H4C)[9 aa] | A | 96.6 /99.6 |
29 /29 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
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358 | pdb_id | contact mol | homologue | ||||
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a3 | description | a4 | identity[%]5 | Ncon6 | description | |
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G |
ZN
|
A | 100.0 /100.0 |
2 /2 |
E2G051_HUMAN MHC class I antigen |
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H |
ZN
|
A | 100.0 /100.0 |
2 /2 |
E2G051_HUMAN MHC class I antigen |
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I |
ZN
|
A | 100.0 /100.0 |
2 /2 |
E2G051_HUMAN MHC class I antigen |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
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358 | pdb_id | contact mol | homologue | ||||
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a3 | description | a4 | identity[%]5 | Ncon6 | description | |
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A | HLAE_HUMAN HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAI.. | A | 100.0 /99.6 |
3 /3 |
HLAE_HUMAN HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAI.. |
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C | HLAE_HUMAN HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAI.. | A | 100.0 /99.6 |
13 /13 |
HLAE_HUMAN HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAI.. |
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C | HLAE_HUMAN HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAI.. | A | 100.0 /99.6 |
7 /7 |
HLAE_HUMAN HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAI.. |
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A | HLAE_HUMAN HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAI.. | C | 100.0 /99.6 |
6 /6 |
HLAE_HUMAN HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAI.. |
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C | HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. | A | 100.0 /100.0 |
10 /10 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
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358 | pdb_id | contact mol | homologue | ||||
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a3 | description | a4 | identity[%]5 | Ncon6 | description | |
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G |
SO4
|
A | 100.0 /99.6 |
3 /3 |
HLAE_HUMAN HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAI.. |
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J |
SO4
|
A | 100.0 /100.0 |
3 /3 |
E2G051_HUMAN MHC class I antigen |
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P |
SO4
|
C | 100.0 /100.0 |
1 /1 |
E2G051_HUMAN MHC class I antigen |
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Q |
SO4
|
D | 100.0 /100.0 |
3 /3 |
E2G051_HUMAN MHC class I antigen |
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H |
SO4
|
C | 100.0 /100.0 |
2 /2 |
Q59EE1_HUMAN HLA class I histocompatibility antigen, E alpha ch.. |
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M |
SO4
|
A | 100.0 /100.0 |
2 /2 |
E2G051_HUMAN MHC class I antigen |
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O |
SO4
|
A | 100.0 /100.0 |
3 /3 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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R |
SO4
|
A | 100.0 /100.0 |
1 /1 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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S |
SO4
|
A | 100.0 /100.0 |
3 /3 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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DA |
SO4
|
C | 100.0 /100.0 |
1 /1 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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N |
SO4
|
A | 100.0 /100.0 |
2 /2 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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K |
GOL
|
A | 100.0 /100.0 |
4 /4 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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L |
GOL
|
A | 100.0 /100.0 |
4 /4 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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M |
GOL
|
A | 100.0 /100.0 |
5 /5 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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N |
GOL
|
A | 100.0 /100.0 |
4 /4 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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N |
GOL
|
A | 100.0 /100.0 |
2 /2 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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EA |
GOL
|
C | 100.0 /100.0 |
3 /3 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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Z |
GOL
|
C | 100.0 /100.0 |
5 /5 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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IA |
GOL
|
E | 100.0 /100.0 |
1 /1 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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K |
ACT
|
F | 100.0 /100.0 |
1 /1 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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F |
EDO
|
A | 100.0 /99.6 |
5 /5 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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G |
EDO
|
A | 100.0 /99.6 |
4 /4 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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H |
EDO
|
A | 100.0 /99.6 |
5 /5 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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I |
EDO
|
A | 100.0 /99.6 |
6 /6 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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J |
EDO
|
A | 100.0 /99.6 |
3 /3 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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L |
EDO
|
A | 100.0 /99.6 |
3 /3 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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F |
EDO
|
A | 100.0 /99.6 |
4 /4 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
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G |
EDO
|
A | 100.0 /99.6 |
3 /3 |
HLAE_HUMAN HLA class I histocompatibility antigen, alpha chai.. |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. |