PSIBLAST 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Stephen F.
Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005)
"Protein database searches using compositionally adjusted
substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: uniprot_sprot.fasta
571,282 sequences; 206,678,396 total letters
Results from round 1
Query= sp|Q96PD4|IL17F_HUMAN Interleukin-17F OS=Homo sapiens OX=9606
GN=IL17F PE=1 SV=3
Length=163
Score E
Sequences producing significant alignments: (Bits) Value
sp|Q96PD4|IL17F_HUMAN Interleukin-17F OS=Homo sapiens OX=9606 GN=... 340 1e-120
sp|A6N6I9|IL17F_CALJA Interleukin-17F OS=Callithrix jacchus OX=94... 266 7e-92
sp|Q5BJ95|IL17F_RAT Interleukin-17F OS=Rattus norvegicus OX=10116... 203 8e-67
sp|Q7TNI7|IL17F_MOUSE Interleukin-17F OS=Mus musculus OX=10090 GN... 176 4e-56
sp|Q16552|IL17_HUMAN Interleukin-17A OS=Homo sapiens OX=9606 GN=I... 125 3e-36
sp|P24916|IL17_SHV21 Viral interleukin-17 OS=Saimiriine herpesvir... 121 1e-34
sp|O40633|IL17_SHV2C Viral interleukin-17 OS=Saimiriine herpesvir... 120 5e-34
sp|Q687Y7|IL17_BOVIN Interleukin-17A OS=Bos taurus OX=9913 GN=IL1... 118 3e-33
sp|Q60I29|IL17_PIG Interleukin-17A OS=Sus scrofa OX=9823 GN=IL17A... 116 1e-32
sp|Q61453|IL17_RAT Interleukin-17A OS=Rattus norvegicus OX=10116 ... 105 2e-28
sp|Q62386|IL17_MOUSE Interleukin-17A OS=Mus musculus OX=10090 GN=... 100 3e-26
sp|Q9P0M4|IL17C_HUMAN Interleukin-17C OS=Homo sapiens OX=9606 GN=... 70.1 4e-14
sp|Q8TAD2|IL17D_HUMAN Interleukin-17D OS=Homo sapiens OX=9606 GN=... 64.7 4e-12
sp|Q9QXT6|IL17B_MOUSE Interleukin-17B OS=Mus musculus OX=10090 GN... 58.5 5e-10
sp|Q8K4C5|IL17C_MOUSE Interleukin-17C OS=Mus musculus OX=10090 GN... 57.0 3e-09
sp|Q9EQI6|IL17B_MESAU Interleukin-17B (Fragment) OS=Mesocricetus ... 51.2 3e-07
sp|Q8VHH8|IL25_MOUSE Interleukin-25 OS=Mus musculus OX=10090 GN=I... 50.8 3e-07
sp|Q9UHF5|IL17B_HUMAN Interleukin-17B OS=Homo sapiens OX=9606 GN=... 50.4 5e-07
sp|Q9H293|IL25_HUMAN Interleukin-25 OS=Homo sapiens OX=9606 GN=IL... 45.1 4e-05
sp|Q924W6|TRI66_MOUSE Tripartite motif-containing protein 66 OS=M... 32.3 2.1
sp|A9XE49|IL17L_CRAGI Interleukin 17-like protein OS=Crassostrea ... 31.2 2.9
sp|O15016|TRI66_HUMAN Tripartite motif-containing protein 66 OS=H... 31.2 5.3
sp|Q82UZ8|SYP_NITEU Proline--tRNA ligase OS=Nitrosomonas europaea... 30.8 6.6
sp|Q8IH18|4ET_DROME Eukaryotic translation initiation factor 4E t... 30.4 7.8
sp|O96553|C1TC_DROME C-1-tetrahydrofolate synthase, cytoplasmic O... 30.4 8.4
>sp|Q96PD4|IL17F_HUMAN Interleukin-17F OS=Homo sapiens OX=9606
GN=IL17F PE=1 SV=3
Length=163
Score = 340 bits (871), Expect = 1e-120, Method: Compositional matrix adjust.
Identities = 163/163 (100%), Positives = 163/163 (100%), Gaps = 0/163 (0%)
Query 1 MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIG 60
MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIG
Sbjct 1 MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIG 60
Query 61 IINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNS 120
IINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNS
Sbjct 61 IINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNS 120
Query 121 VPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ 163
VPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ
Sbjct 121 VPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ 163
>sp|A6N6I9|IL17F_CALJA Interleukin-17F OS=Callithrix jacchus OX=9483
GN=IL17F PE=2 SV=1
Length=163
Score = 266 bits (681), Expect = 7e-92, Method: Compositional matrix adjust.
Identities = 136/163 (83%), Positives = 148/163 (91%), Gaps = 0/163 (0%)
Query 1 MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIG 60
MTVK+LH AMVKYLLL ILGLAFL E AA+++PK G TFFQKPESCP VP GS+KLD+G
Sbjct 1 MTVKSLHVTAMVKYLLLLILGLAFLRETAAQRVPKEGQTFFQKPESCPSVPEGSLKLDLG 60
Query 61 IINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNS 120
IIN NQRV +SRNIE RSTSPWNYTVTWDPNRYPSEVVQAQCR+LGC+NAQGKEDI MNS
Sbjct 61 IINANQRVPLSRNIERRSTSPWNYTVTWDPNRYPSEVVQAQCRHLGCVNAQGKEDIFMNS 120
Query 121 VPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ 163
VPIQQETLV+RRKHQGCSVSFQLEK+LVTVGCTCV P+IHHV
Sbjct 121 VPIQQETLVLRRKHQGCSVSFQLEKLLVTVGCTCVKPLIHHVH 163
>sp|Q5BJ95|IL17F_RAT Interleukin-17F OS=Rattus norvegicus OX=10116
GN=Il17f PE=2 SV=2
Length=161
Score = 203 bits (517), Expect = 8e-67, Method: Compositional matrix adjust.
Identities = 91/152 (60%), Positives = 122/152 (80%), Gaps = 0/152 (0%)
Query 11 MVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIGIINENQRVSM 70
MVK LLL +LG A +S AAR+ PKVG + QK +CPP+ S+++DI I N+NQ +S+
Sbjct 9 MVKSLLLLMLGFAIISSGAARRNPKVGLSALQKAGNCPPLEDNSVRVDIRIFNQNQGISV 68
Query 71 SRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVV 130
R+ ++RS+SPW+Y +T DP+R+PSE+ +AQCR+ GCINAQG+ED SMNSVPIQQE LV+
Sbjct 69 PRDFQNRSSSPWDYNITRDPDRFPSEIAEAQCRHSGCINAQGQEDGSMNSVPIQQEILVL 128
Query 131 RRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHV 162
RR+ QGCS SF+LEK+L+ VGCTCVTP++HH
Sbjct 129 RREPQGCSNSFRLEKMLIKVGCTCVTPIVHHA 160
>sp|Q7TNI7|IL17F_MOUSE Interleukin-17F OS=Mus musculus OX=10090
GN=Il17f PE=1 SV=1
Length=161
Score = 176 bits (446), Expect = 4e-56, Method: Compositional matrix adjust.
Identities = 90/160 (56%), Positives = 120/160 (75%), Gaps = 0/160 (0%)
Query 3 VKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIGII 62
+K AMVK LLL +LGLA L E AARK PK G QK +CPP+ ++++DI I
Sbjct 1 MKCTRETAMVKSLLLLMLGLAILREVAARKNPKAGVPALQKAGNCPPLEDNTVRVDIRIF 60
Query 63 NENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVP 122
N+NQ +S+ R ++RS+SPW+Y +T DP+R+PSE+ +AQCR+ GCINAQG+ED +MNSV
Sbjct 61 NQNQGISVPREFQNRSSSPWDYNITRDPHRFPSEIAEAQCRHSGCINAQGQEDSTMNSVA 120
Query 123 IQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHV 162
IQQE LV+RR+ QGCS SF+LEK+L+ VGCTCV P++H
Sbjct 121 IQQEILVLRREPQGCSNSFRLEKMLLKVGCTCVKPIVHQA 160
>sp|Q16552|IL17_HUMAN Interleukin-17A OS=Homo sapiens OX=9606
GN=IL17A PE=1 SV=1
Length=155
Score = 125 bits (315), Expect = 3e-36, Method: Compositional matrix adjust.
Identities = 61/108 (56%), Positives = 76/108 (70%), Gaps = 0/108 (0%)
Query 55 MKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKE 114
+ L+I N N S + +RSTSPWN DP RYPS + +A+CR+LGCINA G
Sbjct 47 VNLNIHNRNTNTNPKRSSDYYNRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNV 106
Query 115 DISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHV 162
D MNSVPIQQE LV+RR+ C SF+LEK+LV+VGCTCVTP++HHV
Sbjct 107 DYHMNSVPIQQEILVLRREPPHCPNSFRLEKILVSVGCTCVTPIVHHV 154
>sp|P24916|IL17_SHV21 Viral interleukin-17 OS=Saimiriine herpesvirus
2 (strain 11) OX=10383 GN=13 PE=3 SV=1
Length=151
Score = 121 bits (304), Expect = 1e-34, Method: Compositional matrix adjust.
Identities = 59/110 (54%), Positives = 76/110 (69%), Gaps = 0/110 (0%)
Query 54 SMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGK 113
S+ + + I N N + + +RSTSPW D +RYPS + +A+CR LGC+NA G
Sbjct 42 SVMVTLSIRNWNTSSKRASDYYNRSTSPWTLHRNEDQDRYPSVIWEAKCRYLGCVNADGN 101
Query 114 EDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ 163
D MNSVPIQQE LVVR+ HQ C SF+LEK+LVTVGCTCVTP++H+V
Sbjct 102 VDYHMNSVPIQQEILVVRKGHQPCPNSFRLEKMLVTVGCTCVTPIVHNVD 151
>sp|O40633|IL17_SHV2C Viral interleukin-17 OS=Saimiriine herpesvirus
2 (strain 488) OX=10384 GN=13 PE=3 SV=1
Length=151
Score = 120 bits (300), Expect = 5e-34, Method: Compositional matrix adjust.
Identities = 58/110 (53%), Positives = 75/110 (68%), Gaps = 0/110 (0%)
Query 54 SMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGK 113
S+ + + I N N + + +RSTSPW D +RYPS + +A+CR LGC+NA G
Sbjct 42 SVMVTLSIRNWNTSSKRASDYYNRSTSPWTLYRNEDQDRYPSVIWEAKCRYLGCVNADGN 101
Query 114 EDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ 163
D MNSVPIQQE LVVR+ H C SF+LEK+LVTVGCTCVTP++H+V
Sbjct 102 VDYHMNSVPIQQEILVVRKGHNPCPNSFRLEKMLVTVGCTCVTPIVHNVD 151
>sp|Q687Y7|IL17_BOVIN Interleukin-17A OS=Bos taurus OX=9913 GN=IL17A
PE=2 SV=1
Length=153
Score = 118 bits (295), Expect = 3e-33, Method: Compositional matrix adjust.
Identities = 61/132 (46%), Positives = 82/132 (62%), Gaps = 5/132 (4%)
Query 35 KVGHTFFQKPESCPPVPGGS----MKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDP 90
K G Q P CPP + +++++ I+N + + RSTSPW DP
Sbjct 22 KAGVIIPQSP-GCPPTEDKNFPQHVRVNLNIVNRSTNSRRPTDYHKRSTSPWTLHRNEDP 80
Query 91 NRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTV 150
RYPS + +A+C + GCINA+GK D MNSV IQQE LV+RR+ Q C SF+LEK+LV V
Sbjct 81 ERYPSVIWEAKCSHSGCINAEGKVDHHMNSVTIQQEILVLRRESQHCPHSFRLEKMLVAV 140
Query 151 GCTCVTPVIHHV 162
GCTCVTP++ H+
Sbjct 141 GCTCVTPIVRHL 152
>sp|Q60I29|IL17_PIG Interleukin-17A OS=Sus scrofa OX=9823 GN=IL17A
PE=2 SV=1
Length=153
Score = 116 bits (291), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 54/108 (50%), Positives = 75/108 (69%), Gaps = 0/108 (0%)
Query 55 MKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKE 114
+++++ I+N + + R TSPW DP RY S + +A+C + GCINA+GKE
Sbjct 45 VRVNLNILNRSTPARRPSDYSKRFTSPWTLQRNEDPERYSSVIWEAKCSHSGCINAEGKE 104
Query 115 DISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHV 162
D MNSVPIQQE LV+RR+ + C SF+LEKV+VTVGCTCVTP++ H+
Sbjct 105 DHHMNSVPIQQEILVLRREPRHCPNSFRLEKVMVTVGCTCVTPIVRHI 152
>sp|Q61453|IL17_RAT Interleukin-17A OS=Rattus norvegicus OX=10116
GN=Il17a PE=2 SV=1
Length=150
Score = 105 bits (262), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 51/111 (46%), Positives = 78/111 (70%), Gaps = 3/111 (3%)
Query 54 SMKLDIGIINENQRVSMSR---NIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINA 110
++K+++ +IN + SR + +RSTSPW + DP+RYPS + +AQCR+ C+NA
Sbjct 38 NVKVNLKVINSLSSKASSRRPSDYLNRSTSPWTLSRNEDPDRYPSVIWEAQCRHQRCVNA 97
Query 111 QGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHH 161
+GK D MNSV IQQE LV++R+ + C +F++EK+LV VGCTCV+ ++ H
Sbjct 98 EGKLDHHMNSVLIQQEILVLKREPEKCPFTFRVEKMLVGVGCTCVSSIVRH 148
>sp|Q62386|IL17_MOUSE Interleukin-17A OS=Mus musculus OX=10090
GN=Il17a PE=1 SV=1
Length=158
Score = 100 bits (248), Expect = 3e-26, Method: Compositional matrix adjust.
Identities = 50/112 (45%), Positives = 75/112 (67%), Gaps = 3/112 (3%)
Query 54 SMKLDIGIINE-NQRVSMSR--NIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINA 110
++K+++ + N +VS R + +RSTSPW DP+RYPS + +AQCR+ C+NA
Sbjct 46 NVKVNLKVFNSLGAKVSSRRPSDYLNRSTSPWTLHRNEDPDRYPSVIWEAQCRHQRCVNA 105
Query 111 QGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHV 162
+GK D MNSV IQQE LV++R+ + C +F++EK+LV VGCTCV ++
Sbjct 106 EGKLDHHMNSVLIQQEILVLKREPESCPFTFRVEKMLVGVGCTCVASIVRQA 157
>sp|Q9P0M4|IL17C_HUMAN Interleukin-17C OS=Homo sapiens OX=9606
GN=IL17C PE=1 SV=1
Length=197
Score = 70.1 bits (170), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 39/100 (39%), Positives = 55/100 (55%), Gaps = 14/100 (14%)
Query 70 MSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQ-GKEDISMNSVPIQQETL 128
+ + RS SPW Y V D +RYP ++ A+C GCI+A+ G+E ++NSV + Q L
Sbjct 97 LEADTHQRSISPWRYRVDTDEDRYPQKLAFAECLCRGCIDARTGRETAALNSVRLLQSLL 156
Query 129 VVRRKHQGCS-----------VSFQLEKVLVTVGCTCVTP 157
V+RR+ CS +F E + V VGCTCV P
Sbjct 157 VLRRR--PCSRDGSGLPTPGAFAFHTEFIHVPVGCTCVLP 194
>sp|Q8TAD2|IL17D_HUMAN Interleukin-17D OS=Homo sapiens OX=9606
GN=IL17D PE=2 SV=1
Length=202
Score = 64.7 bits (156), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 32/82 (39%), Positives = 45/82 (55%), Gaps = 3/82 (4%)
Query 77 RSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQ-GKEDISMNSVPIQQETLVVRRKH- 134
RS SPW Y +++DP RYP + +A C GC+ G+ED+ S P+ T+V+RR
Sbjct 89 RSVSPWAYRISYDPARYPRYLPEAYCLCRGCLTGLFGEEDVRFRSAPVYMPTVVLRRTPA 148
Query 135 -QGCSVSFQLEKVLVTVGCTCV 155
G + V + VGCTCV
Sbjct 149 CAGGRSVYTEAYVTIPVGCTCV 170
>sp|Q9QXT6|IL17B_MOUSE Interleukin-17B OS=Mus musculus OX=10090
GN=Il17b PE=2 SV=1
Length=180
Score = 58.5 bits (140), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 33/86 (38%), Positives = 49/86 (57%), Gaps = 9/86 (10%)
Query 77 RSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINA-QGKEDISMNSVPIQQETLVVRR--- 132
RS SPW Y++ DP+R P+++ +A+C LGC+N +ED SM SVP+ + V RR
Sbjct 96 RSLSPWGYSINHDPSRIPADLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCP 155
Query 133 ---KHQGCSVSFQLEKVLVTVGCTCV 155
+ C +E + VGCTC+
Sbjct 156 QPPRPGPCRQRVVMET--IAVGCTCI 179
>sp|Q8K4C5|IL17C_MOUSE Interleukin-17C OS=Mus musculus OX=10090
GN=Il17c PE=1 SV=1
Length=194
Score = 57.0 bits (136), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 14/100 (14%)
Query 70 MSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQ-GKEDISMNSVPIQQETL 128
+ + RS SPW Y + D NRYP ++ A+C GCINA+ G+E ++NSV Q
Sbjct 93 LEADTHERSISPWRYRIDTDENRYPQKLAVAECLCRGCINAKTGRETAALNSV--QLLQS 150
Query 129 VVRRKHQGC-----------SVSFQLEKVLVTVGCTCVTP 157
++ + Q C S +F E + V VGCTCV P
Sbjct 151 LLVLRRQPCSRDGTADPTPGSFAFHTEFIRVPVGCTCVLP 190
>sp|Q9EQI6|IL17B_MESAU Interleukin-17B (Fragment) OS=Mesocricetus
auratus OX=10036 GN=IL17B PE=2 SV=1
Length=178
Score = 51.2 bits (121), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 32/83 (39%), Positives = 45/83 (54%), Gaps = 5/83 (6%)
Query 77 RSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINA-QGKEDISMNSVPIQQETLVVRRKHQ 135
RS SPW Y++ DP+R P+++ +A+C LGC+N +ED SM SVP+ + V RR
Sbjct 96 RSLSPWGYSINHDPSRIPADLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCP 155
Query 136 GCSVSFQLEKVLV----TVGCTC 154
+V VGCTC
Sbjct 156 PPPRPGPCRHRVVMETIAVGCTC 178
>sp|Q8VHH8|IL25_MOUSE Interleukin-25 OS=Mus musculus OX=10090
GN=Il25 PE=2 SV=1
Length=169
Score = 50.8 bits (120), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 33/104 (32%), Positives = 51/104 (49%), Gaps = 8/104 (8%)
Query 64 ENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQ--GKEDISMNSV 121
E+ R S + SR+ SPW+Y + D NR P ++ A+C C++ Q D NSV
Sbjct 64 ESCRASKDGPLNSRAISPWSYELDRDLNRVPQDLYHARCLCPHCVSLQTGSHMDPLGNSV 123
Query 122 PIQQETLVVRRK----HQGCSVSFQLEKVL--VTVGCTCVTPVI 159
P+ V R+ +G + LE+ L V++ C CV P +
Sbjct 124 PLYHNQTVFYRRPCHGEEGTHRRYCLERRLYRVSLACVCVRPRV 167
>sp|Q9UHF5|IL17B_HUMAN Interleukin-17B OS=Homo sapiens OX=9606
GN=IL17B PE=2 SV=1
Length=180
Score = 50.4 bits (119), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 33/86 (38%), Positives = 47/86 (55%), Gaps = 9/86 (10%)
Query 77 RSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINA-QGKEDISMNSVPIQQETLVVRRKHQ 135
RS SPW Y++ DP+R P ++ +A+C LGC+N +ED SM SVP+ + V RR
Sbjct 96 RSLSPWGYSINHDPSRIPVDLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCP 155
Query 136 G------CSVSFQLEKVLVTVGCTCV 155
C +E + VGCTC+
Sbjct 156 PPPRTGPCRQRAVMET--IAVGCTCI 179
>sp|Q9H293|IL25_HUMAN Interleukin-25 OS=Homo sapiens OX=9606 GN=IL25
PE=1 SV=1
Length=177
Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 31/104 (30%), Positives = 48/104 (46%), Gaps = 8/104 (8%)
Query 64 ENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQ--GKEDISMNSV 121
E+ R S + SR+ SPW Y + D NR P ++ A+C C++ Q D NS
Sbjct 72 ESCRASEDGPLNSRAISPWRYELDRDLNRLPQDLYHARCLCPHCVSLQTGSHMDPRGNSE 131
Query 122 PIQQETLVVRRK----HQGCSVSFQLEKVL--VTVGCTCVTPVI 159
+ V R+ +G + LE+ L V++ C CV P +
Sbjct 132 LLYHNQTVFYRRPCHGEKGTHKGYCLERRLYRVSLACVCVRPRV 175
>sp|Q924W6|TRI66_MOUSE Tripartite motif-containing protein 66
OS=Mus musculus OX=10090 GN=Trim66 PE=1 SV=4
Length=1344
Score = 32.3 bits (72), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 9/47 (19%)
Query 70 MSRNIESRST----SPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQG 112
M R +E+R SPW+ TW+PN + ++ +LGCI +G
Sbjct 330 MQRLLETRCNTDPGSPWSIRFTWEPNFWTKQLA-----SLGCITTEG 371
>sp|A9XE49|IL17L_CRAGI Interleukin 17-like protein OS=Crassostrea
gigas OX=29159 PE=2 SV=1
Length=200
Score = 31.2 bits (69), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 21/83 (25%), Positives = 37/83 (45%), Gaps = 5/83 (6%)
Query 77 RSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCI--NAQGKEDISMNSVPIQQETLVVRRKH 134
R+T P+ + RYP + +A+C+ GC+ G D++ P+ + V+ R
Sbjct 97 RTTCPYFLVASHLSTRYPKIITEARCKCSGCVPLEENGHSDLT-RCEPVYRPVRVLSRTG 155
Query 135 QGCSVSFQLEKV--LVTVGCTCV 155
+ +Q + GCTCV
Sbjct 156 NCVNGVYQYAAAVHMKQEGCTCV 178
>sp|O15016|TRI66_HUMAN Tripartite motif-containing protein 66
OS=Homo sapiens OX=9606 GN=TRIM66 PE=1 SV=5
Length=1351
Score = 31.2 bits (69), Expect = 5.3, Method: Compositional matrix adjust.
Identities = 15/52 (29%), Positives = 28/52 (54%), Gaps = 6/52 (12%)
Query 61 IINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQG 112
I+ + QR+ + + + SPW+ TW+PN + ++ +LGCI +G
Sbjct 328 IVFQMQRL-LETSCNTDPGSPWSIRFTWEPNFWTKQLA-----SLGCITTEG 373
>sp|Q82UZ8|SYP_NITEU Proline--tRNA ligase OS=Nitrosomonas europaea
(strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)
OX=228410 GN=proS PE=3 SV=1
Length=568
Score = 30.8 bits (68), Expect = 6.6, Method: Composition-based stats.
Identities = 25/76 (33%), Positives = 35/76 (46%), Gaps = 6/76 (8%)
Query 2 TVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPE------SCPPVPGGSM 55
T+K L A K+ LL + G L+E RKIP +G F + SCPP G +
Sbjct 277 TLKALAVTAGGKFYLLLLRGDHQLNETKVRKIPFLGDFEFAEESRIIAEMSCPPGYLGPV 336
Query 56 KLDIGIINENQRVSMS 71
+ II + + MS
Sbjct 337 GVKAEIIADRAVLEMS 352
>sp|Q8IH18|4ET_DROME Eukaryotic translation initiation factor
4E transporter OS=Drosophila melanogaster OX=7227 GN=4E-T PE=1
SV=1
Length=1010
Score = 30.4 bits (67), Expect = 7.8, Method: Compositional matrix adjust.
Identities = 18/46 (39%), Positives = 22/46 (48%), Gaps = 1/46 (2%)
Query 44 PESCPPVPGGSMKLDIG-IINENQRVSMSRNIESRSTSPWNYTVTW 88
P+ PPVPG S D G +I N S S + R +SP N W
Sbjct 924 PQMSPPVPGFSDSSDSGNVIKANSLTSPSYQRDERISSPTNQLAQW 969
>sp|O96553|C1TC_DROME C-1-tetrahydrofolate synthase, cytoplasmic
OS=Drosophila melanogaster OX=7227 GN=pug PE=2 SV=4
Length=968
Score = 30.4 bits (67), Expect = 8.4, Method: Compositional matrix adjust.
Identities = 21/68 (31%), Positives = 34/68 (50%), Gaps = 2/68 (3%)
Query 49 PVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNY-TVTWDPNR-YPSEVVQAQCRNLG 106
PVPGG + + ++ +N S +R +E + S W T+ P R PS++V A+ +
Sbjct 303 PVPGGVGPMTVAMLMKNTVRSAARFLERLAKSQWALQTLPLKPQRPVPSDIVIARAQKPK 362
Query 107 CINAQGKE 114
I KE
Sbjct 363 DIAVLAKE 370
Lambda K H a alpha
0.320 0.133 0.406 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 7798067532
Results from round 2
Query= sp|Q96PD4|IL17F_HUMAN Interleukin-17F OS=Homo sapiens OX=9606
GN=IL17F PE=1 SV=3
Length=163
Score E
Sequences producing significant alignments: (Bits) Value
Sequences used in model and found again:
sp|Q96PD4|IL17F_HUMAN Interleukin-17F OS=Homo sapiens OX=9606 GN=... 254 8e-87
sp|Q5BJ95|IL17F_RAT Interleukin-17F OS=Rattus norvegicus OX=10116... 247 4e-84
sp|A6N6I9|IL17F_CALJA Interleukin-17F OS=Callithrix jacchus OX=94... 225 2e-75
sp|Q7TNI7|IL17F_MOUSE Interleukin-17F OS=Mus musculus OX=10090 GN... 221 1e-73
sp|Q687Y7|IL17_BOVIN Interleukin-17A OS=Bos taurus OX=9913 GN=IL1... 181 4e-58
sp|Q16552|IL17_HUMAN Interleukin-17A OS=Homo sapiens OX=9606 GN=I... 178 5e-57
sp|Q60I29|IL17_PIG Interleukin-17A OS=Sus scrofa OX=9823 GN=IL17A... 174 2e-55
sp|P24916|IL17_SHV21 Viral interleukin-17 OS=Saimiriine herpesvir... 166 3e-52
sp|O40633|IL17_SHV2C Viral interleukin-17 OS=Saimiriine herpesvir... 163 3e-51
sp|Q62386|IL17_MOUSE Interleukin-17A OS=Mus musculus OX=10090 GN=... 161 5e-50
sp|Q61453|IL17_RAT Interleukin-17A OS=Rattus norvegicus OX=10116 ... 158 4e-49
sp|Q8VHH8|IL25_MOUSE Interleukin-25 OS=Mus musculus OX=10090 GN=I... 115 6e-32
sp|Q9H293|IL25_HUMAN Interleukin-25 OS=Homo sapiens OX=9606 GN=IL... 113 5e-31
sp|Q9P0M4|IL17C_HUMAN Interleukin-17C OS=Homo sapiens OX=9606 GN=... 112 2e-30
sp|Q8TAD2|IL17D_HUMAN Interleukin-17D OS=Homo sapiens OX=9606 GN=... 104 3e-27
sp|Q9QXT6|IL17B_MOUSE Interleukin-17B OS=Mus musculus OX=10090 GN... 102 6e-27
sp|Q8K4C5|IL17C_MOUSE Interleukin-17C OS=Mus musculus OX=10090 GN... 95.1 7e-24
sp|Q9UHF5|IL17B_HUMAN Interleukin-17B OS=Homo sapiens OX=9606 GN=... 93.6 2e-23
sp|Q9EQI6|IL17B_MESAU Interleukin-17B (Fragment) OS=Mesocricetus ... 86.7 9e-21
Sequences not found previously or not previously below threshold:
sp|A9XE49|IL17L_CRAGI Interleukin 17-like protein OS=Crassostrea ... 49.3 2e-06
sp|Q4R1H1|TYRP2_PIG L-dopachrome tautomerase OS=Sus scrofa OX=982... 38.9 0.010
sp|Q22687|IL171_CAEEL Interleukin cytokine-related protein 17.1 O... 35.8 0.093
sp|Q95119|TYRP2_BOVIN L-dopachrome tautomerase OS=Bos taurus OX=9... 35.8 0.14
sp|Q5NL15|PANC_ZYMMO Pantothenate synthetase OS=Zymomonas mobilis... 33.9 0.42
>sp|Q96PD4|IL17F_HUMAN Interleukin-17F OS=Homo sapiens OX=9606
GN=IL17F PE=1 SV=3
Length=163
Score = 254 bits (648), Expect = 8e-87, Method: Composition-based stats.
Identities = 163/163 (100%), Positives = 163/163 (100%), Gaps = 0/163 (0%)
Query 1 MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIG 60
MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIG
Sbjct 1 MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIG 60
Query 61 IINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNS 120
IINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNS
Sbjct 61 IINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNS 120
Query 121 VPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ 163
VPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ
Sbjct 121 VPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ 163
>sp|Q5BJ95|IL17F_RAT Interleukin-17F OS=Rattus norvegicus OX=10116
GN=Il17f PE=2 SV=2
Length=161
Score = 247 bits (630), Expect = 4e-84, Method: Composition-based stats.
Identities = 92/160 (58%), Positives = 124/160 (78%), Gaps = 0/160 (0%)
Query 3 VKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIGII 62
+K MVK LLL +LG A +S AAR+ PKVG + QK +CPP+ S+++DI I
Sbjct 1 MKGSCETTMVKSLLLLMLGFAIISSGAARRNPKVGLSALQKAGNCPPLEDNSVRVDIRIF 60
Query 63 NENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVP 122
N+NQ +S+ R+ ++RS+SPW+Y +T DP+R+PSE+ +AQCR+ GCINAQG+ED SMNSVP
Sbjct 61 NQNQGISVPRDFQNRSSSPWDYNITRDPDRFPSEIAEAQCRHSGCINAQGQEDGSMNSVP 120
Query 123 IQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHV 162
IQQE LV+RR+ QGCS SF+LEK+L+ VGCTCVTP++HH
Sbjct 121 IQQEILVLRREPQGCSNSFRLEKMLIKVGCTCVTPIVHHA 160
>sp|A6N6I9|IL17F_CALJA Interleukin-17F OS=Callithrix jacchus OX=9483
GN=IL17F PE=2 SV=1
Length=163
Score = 225 bits (573), Expect = 2e-75, Method: Composition-based stats.
Identities = 136/163 (83%), Positives = 148/163 (91%), Gaps = 0/163 (0%)
Query 1 MTVKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIG 60
MTVK+LH AMVKYLLL ILGLAFL E AA+++PK G TFFQKPESCP VP GS+KLD+G
Sbjct 1 MTVKSLHVTAMVKYLLLLILGLAFLRETAAQRVPKEGQTFFQKPESCPSVPEGSLKLDLG 60
Query 61 IINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNS 120
IIN NQRV +SRNIE RSTSPWNYTVTWDPNRYPSEVVQAQCR+LGC+NAQGKEDI MNS
Sbjct 61 IINANQRVPLSRNIERRSTSPWNYTVTWDPNRYPSEVVQAQCRHLGCVNAQGKEDIFMNS 120
Query 121 VPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ 163
VPIQQETLV+RRKHQGCSVSFQLEK+LVTVGCTCV P+IHHV
Sbjct 121 VPIQQETLVLRRKHQGCSVSFQLEKLLVTVGCTCVKPLIHHVH 163
>sp|Q7TNI7|IL17F_MOUSE Interleukin-17F OS=Mus musculus OX=10090
GN=Il17f PE=1 SV=1
Length=161
Score = 221 bits (562), Expect = 1e-73, Method: Composition-based stats.
Identities = 90/160 (56%), Positives = 120/160 (75%), Gaps = 0/160 (0%)
Query 3 VKTLHGPAMVKYLLLSILGLAFLSEAAARKIPKVGHTFFQKPESCPPVPGGSMKLDIGII 62
+K AMVK LLL +LGLA L E AARK PK G QK +CPP+ ++++DI I
Sbjct 1 MKCTRETAMVKSLLLLMLGLAILREVAARKNPKAGVPALQKAGNCPPLEDNTVRVDIRIF 60
Query 63 NENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVP 122
N+NQ +S+ R ++RS+SPW+Y +T DP+R+PSE+ +AQCR+ GCINAQG+ED +MNSV
Sbjct 61 NQNQGISVPREFQNRSSSPWDYNITRDPHRFPSEIAEAQCRHSGCINAQGQEDSTMNSVA 120
Query 123 IQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHV 162
IQQE LV+RR+ QGCS SF+LEK+L+ VGCTCV P++H
Sbjct 121 IQQEILVLRREPQGCSNSFRLEKMLLKVGCTCVKPIVHQA 160
>sp|Q687Y7|IL17_BOVIN Interleukin-17A OS=Bos taurus OX=9913 GN=IL17A
PE=2 SV=1
Length=153
Score = 181 bits (459), Expect = 4e-58, Method: Composition-based stats.
Identities = 61/132 (46%), Positives = 82/132 (62%), Gaps = 5/132 (4%)
Query 35 KVGHTFFQKPESCPPVPGGS----MKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDP 90
K G Q P CPP + +++++ I+N + + RSTSPW DP
Sbjct 22 KAGVIIPQSPG-CPPTEDKNFPQHVRVNLNIVNRSTNSRRPTDYHKRSTSPWTLHRNEDP 80
Query 91 NRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTV 150
RYPS + +A+C + GCINA+GK D MNSV IQQE LV+RR+ Q C SF+LEK+LV V
Sbjct 81 ERYPSVIWEAKCSHSGCINAEGKVDHHMNSVTIQQEILVLRRESQHCPHSFRLEKMLVAV 140
Query 151 GCTCVTPVIHHV 162
GCTCVTP++ H+
Sbjct 141 GCTCVTPIVRHL 152
>sp|Q16552|IL17_HUMAN Interleukin-17A OS=Homo sapiens OX=9606
GN=IL17A PE=1 SV=1
Length=155
Score = 178 bits (452), Expect = 5e-57, Method: Composition-based stats.
Identities = 67/134 (50%), Positives = 84/134 (63%), Gaps = 7/134 (5%)
Query 35 KVGHTFFQKPESCPPVPGGS------MKLDIGIINENQRVSMSRNIESRSTSPWNYTVTW 88
K G T + P CP + + L+I N N S + +RSTSPWN
Sbjct 22 KAGITIPRNPG-CPNSEDKNFPRTVMVNLNIHNRNTNTNPKRSSDYYNRSTSPWNLHRNE 80
Query 89 DPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLV 148
DP RYPS + +A+CR+LGCINA G D MNSVPIQQE LV+RR+ C SF+LEK+LV
Sbjct 81 DPERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQEILVLRREPPHCPNSFRLEKILV 140
Query 149 TVGCTCVTPVIHHV 162
+VGCTCVTP++HHV
Sbjct 141 SVGCTCVTPIVHHV 154
>sp|Q60I29|IL17_PIG Interleukin-17A OS=Sus scrofa OX=9823 GN=IL17A
PE=2 SV=1
Length=153
Score = 174 bits (441), Expect = 2e-55, Method: Composition-based stats.
Identities = 60/132 (45%), Positives = 82/132 (62%), Gaps = 5/132 (4%)
Query 35 KVGHTFFQKPESCPPVPGGS----MKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDP 90
K G Q P CP + +++++ I+N + + R TSPW DP
Sbjct 22 KAGIMIPQSPG-CPKTEDKNFPQHVRVNLNILNRSTPARRPSDYSKRFTSPWTLQRNEDP 80
Query 91 NRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTV 150
RY S + +A+C + GCINA+GKED MNSVPIQQE LV+RR+ + C SF+LEKV+VTV
Sbjct 81 ERYSSVIWEAKCSHSGCINAEGKEDHHMNSVPIQQEILVLRREPRHCPNSFRLEKVMVTV 140
Query 151 GCTCVTPVIHHV 162
GCTCVTP++ H+
Sbjct 141 GCTCVTPIVRHI 152
>sp|P24916|IL17_SHV21 Viral interleukin-17 OS=Saimiriine herpesvirus
2 (strain 11) OX=10383 GN=13 PE=3 SV=1
Length=151
Score = 166 bits (420), Expect = 3e-52, Method: Composition-based stats.
Identities = 59/110 (54%), Positives = 76/110 (69%), Gaps = 0/110 (0%)
Query 54 SMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGK 113
S+ + + I N N + + +RSTSPW D +RYPS + +A+CR LGC+NA G
Sbjct 42 SVMVTLSIRNWNTSSKRASDYYNRSTSPWTLHRNEDQDRYPSVIWEAKCRYLGCVNADGN 101
Query 114 EDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ 163
D MNSVPIQQE LVVR+ HQ C SF+LEK+LVTVGCTCVTP++H+V
Sbjct 102 VDYHMNSVPIQQEILVVRKGHQPCPNSFRLEKMLVTVGCTCVTPIVHNVD 151
>sp|O40633|IL17_SHV2C Viral interleukin-17 OS=Saimiriine herpesvirus
2 (strain 488) OX=10384 GN=13 PE=3 SV=1
Length=151
Score = 163 bits (413), Expect = 3e-51, Method: Composition-based stats.
Identities = 58/110 (53%), Positives = 75/110 (68%), Gaps = 0/110 (0%)
Query 54 SMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGK 113
S+ + + I N N + + +RSTSPW D +RYPS + +A+CR LGC+NA G
Sbjct 42 SVMVTLSIRNWNTSSKRASDYYNRSTSPWTLYRNEDQDRYPSVIWEAKCRYLGCVNADGN 101
Query 114 EDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ 163
D MNSVPIQQE LVVR+ H C SF+LEK+LVTVGCTCVTP++H+V
Sbjct 102 VDYHMNSVPIQQEILVVRKGHNPCPNSFRLEKMLVTVGCTCVTPIVHNVD 151
>sp|Q62386|IL17_MOUSE Interleukin-17A OS=Mus musculus OX=10090
GN=Il17a PE=1 SV=1
Length=158
Score = 161 bits (406), Expect = 5e-50, Method: Composition-based stats.
Identities = 51/135 (38%), Positives = 76/135 (56%), Gaps = 8/135 (6%)
Query 35 KVGHTFFQKPESCPPVPGG----SMKLDIGIINE---NQRVSMSRNIESRSTSPWNYTVT 87
K Q +CP ++K+++ + N + +RSTSPW
Sbjct 24 KAAAIIPQSS-ACPNTEAKDFLQNVKVNLKVFNSLGAKVSSRRPSDYLNRSTSPWTLHRN 82
Query 88 WDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVL 147
DP+RYPS + +AQCR+ C+NA+GK D MNSV IQQE LV++R+ + C +F++EK+L
Sbjct 83 EDPDRYPSVIWEAQCRHQRCVNAEGKLDHHMNSVLIQQEILVLKREPESCPFTFRVEKML 142
Query 148 VTVGCTCVTPVIHHV 162
V VGCTCV ++
Sbjct 143 VGVGCTCVASIVRQA 157
>sp|Q61453|IL17_RAT Interleukin-17A OS=Rattus norvegicus OX=10116
GN=Il17a PE=2 SV=1
Length=150
Score = 158 bits (399), Expect = 4e-49, Method: Composition-based stats.
Identities = 53/135 (39%), Positives = 79/135 (59%), Gaps = 8/135 (6%)
Query 35 KVGHTFFQKPESCPPVPGGS----MKLDIGIINE---NQRVSMSRNIESRSTSPWNYTVT 87
K Q CP + +K+++ +IN + +RSTSPW +
Sbjct 16 KAAVLIPQSSV-CPNAEANNFLQNVKVNLKVINSLSSKASSRRPSDYLNRSTSPWTLSRN 74
Query 88 WDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVL 147
DP+RYPS + +AQCR+ C+NA+GK D MNSV IQQE LV++R+ + C +F++EK+L
Sbjct 75 EDPDRYPSVIWEAQCRHQRCVNAEGKLDHHMNSVLIQQEILVLKREPEKCPFTFRVEKML 134
Query 148 VTVGCTCVTPVIHHV 162
V VGCTCV+ ++ H
Sbjct 135 VGVGCTCVSSIVRHA 149
>sp|Q8VHH8|IL25_MOUSE Interleukin-25 OS=Mus musculus OX=10090
GN=Il25 PE=2 SV=1
Length=169
Score = 115 bits (287), Expect = 6e-32, Method: Composition-based stats.
Identities = 33/104 (32%), Positives = 51/104 (49%), Gaps = 8/104 (8%)
Query 64 ENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQ--GKEDISMNSV 121
E+ R S + SR+ SPW+Y + D NR P ++ A+C C++ Q D NSV
Sbjct 64 ESCRASKDGPLNSRAISPWSYELDRDLNRVPQDLYHARCLCPHCVSLQTGSHMDPLGNSV 123
Query 122 PIQQETLVVRRKH----QGCSVSFQLEKVL--VTVGCTCVTPVI 159
P+ V R+ +G + LE+ L V++ C CV P +
Sbjct 124 PLYHNQTVFYRRPCHGEEGTHRRYCLERRLYRVSLACVCVRPRV 167
>sp|Q9H293|IL25_HUMAN Interleukin-25 OS=Homo sapiens OX=9606 GN=IL25
PE=1 SV=1
Length=177
Score = 113 bits (282), Expect = 5e-31, Method: Composition-based stats.
Identities = 31/104 (30%), Positives = 48/104 (46%), Gaps = 8/104 (8%)
Query 64 ENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQ--GKEDISMNSV 121
E+ R S + SR+ SPW Y + D NR P ++ A+C C++ Q D NS
Sbjct 72 ESCRASEDGPLNSRAISPWRYELDRDLNRLPQDLYHARCLCPHCVSLQTGSHMDPRGNSE 131
Query 122 PIQQETLVVRRKH----QGCSVSFQLEKVL--VTVGCTCVTPVI 159
+ V R+ +G + LE+ L V++ C CV P +
Sbjct 132 LLYHNQTVFYRRPCHGEKGTHKGYCLERRLYRVSLACVCVRPRV 175
>sp|Q9P0M4|IL17C_HUMAN Interleukin-17C OS=Homo sapiens OX=9606
GN=IL17C PE=1 SV=1
Length=197
Score = 112 bits (279), Expect = 2e-30, Method: Composition-based stats.
Identities = 37/99 (37%), Positives = 53/99 (54%), Gaps = 10/99 (10%)
Query 70 MSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINA-QGKEDISMNSVPIQQETL 128
+ + RS SPW Y V D +RYP ++ A+C GCI+A G+E ++NSV + Q L
Sbjct 97 LEADTHQRSISPWRYRVDTDEDRYPQKLAFAECLCRGCIDARTGRETAALNSVRLLQSLL 156
Query 129 VVRRK---------HQGCSVSFQLEKVLVTVGCTCVTPV 158
V+RR+ + +F E + V VGCTCV P
Sbjct 157 VLRRRPCSRDGSGLPTPGAFAFHTEFIHVPVGCTCVLPR 195
>sp|Q8TAD2|IL17D_HUMAN Interleukin-17D OS=Homo sapiens OX=9606
GN=IL17D PE=2 SV=1
Length=202
Score = 104 bits (259), Expect = 3e-27, Method: Composition-based stats.
Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query 73 NIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQ-GKEDISMNSVPIQQETLVVR 131
RS SPW Y +++DP RYP + +A C GC+ G+ED+ S P+ T+V+R
Sbjct 85 PTNLRSVSPWAYRISYDPARYPRYLPEAYCLCRGCLTGLFGEEDVRFRSAPVYMPTVVLR 144
Query 132 RKH--QGCSVSFQLEKVLVTVGCTCV 155
R G + V + VGCTCV
Sbjct 145 RTPACAGGRSVYTEAYVTIPVGCTCV 170
>sp|Q9QXT6|IL17B_MOUSE Interleukin-17B OS=Mus musculus OX=10090
GN=Il17b PE=2 SV=1
Length=180
Score = 102 bits (255), Expect = 6e-27, Method: Composition-based stats.
Identities = 32/86 (37%), Positives = 47/86 (55%), Gaps = 5/86 (6%)
Query 75 ESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINA-QGKEDISMNSVPIQQETLVVRRK 133
RS SPW Y++ DP+R P+++ +A+C LGC+N +ED SM SVP+ + V RR
Sbjct 94 NKRSLSPWGYSINHDPSRIPADLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRL 153
Query 134 HQGCSVSFQLEKVLV----TVGCTCV 155
+ +V VGCTC+
Sbjct 154 CPQPPRPGPCRQRVVMETIAVGCTCI 179
>sp|Q8K4C5|IL17C_MOUSE Interleukin-17C OS=Mus musculus OX=10090
GN=Il17c PE=1 SV=1
Length=194
Score = 95.1 bits (235), Expect = 7e-24, Method: Composition-based stats.
Identities = 39/99 (39%), Positives = 53/99 (54%), Gaps = 10/99 (10%)
Query 70 MSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINA-QGKEDISMNSVPIQQETL 128
+ + RS SPW Y + D NRYP ++ A+C GCINA G+E ++NSV + Q L
Sbjct 93 LEADTHERSISPWRYRIDTDENRYPQKLAVAECLCRGCINAKTGRETAALNSVQLLQSLL 152
Query 129 VVRRK---------HQGCSVSFQLEKVLVTVGCTCVTPV 158
V+RR+ S +F E + V VGCTCV P
Sbjct 153 VLRRQPCSRDGTADPTPGSFAFHTEFIRVPVGCTCVLPR 191
>sp|Q9UHF5|IL17B_HUMAN Interleukin-17B OS=Homo sapiens OX=9606
GN=IL17B PE=2 SV=1
Length=180
Score = 93.6 bits (231), Expect = 2e-23, Method: Composition-based stats.
Identities = 33/88 (38%), Positives = 47/88 (53%), Gaps = 9/88 (10%)
Query 75 ESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINA-QGKEDISMNSVPIQQETLVVRRK 133
RS SPW Y++ DP+R P ++ +A+C LGC+N +ED SM SVP+ + V RR
Sbjct 94 NKRSLSPWGYSINHDPSRIPVDLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRL 153
Query 134 H------QGCSVSFQLEKVLVTVGCTCV 155
C +E + VGCTC+
Sbjct 154 CPPPPRTGPCRQRAVME--TIAVGCTCI 179
>sp|Q9EQI6|IL17B_MESAU Interleukin-17B (Fragment) OS=Mesocricetus
auratus OX=10036 GN=IL17B PE=2 SV=1
Length=178
Score = 86.7 bits (213), Expect = 9e-21, Method: Composition-based stats.
Identities = 33/107 (31%), Positives = 50/107 (47%), Gaps = 12/107 (11%)
Query 60 GIINENQRVSMSRNIE-------SRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINA-Q 111
+ N ++ + RS SPW Y++ DP+R P+++ +A+C LGC+N
Sbjct 72 QLRNSSEPAKRRCEVNLQLWLSNKRSLSPWGYSINHDPSRIPADLPEARCLCLGCVNPFT 131
Query 112 GKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLV----TVGCTC 154
+ED SM SVP+ + V RR +V VGCTC
Sbjct 132 MQEDRSMVSVPVFSQVPVRRRLCPPPPRPGPCRHRVVMETIAVGCTC 178
>sp|A9XE49|IL17L_CRAGI Interleukin 17-like protein OS=Crassostrea
gigas OX=29159 PE=2 SV=1
Length=200
Score = 49.3 bits (116), Expect = 2e-06, Method: Composition-based stats.
Identities = 20/89 (22%), Positives = 38/89 (43%), Gaps = 5/89 (6%)
Query 72 RNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQ--GKEDISMNSVPIQQETLV 129
++ R+T P+ + RYP + +A+C+ GC+ + G D++ P+ + V
Sbjct 92 SSVFERTTCPYFLVASHLSTRYPKIITEARCKCSGCVPLEENGHSDLT-RCEPVYRPVRV 150
Query 130 VRRK--HQGCSVSFQLEKVLVTVGCTCVT 156
+ R + + GCTCV
Sbjct 151 LSRTGNCVNGVYQYAAAVHMKQEGCTCVR 179
>sp|Q4R1H1|TYRP2_PIG L-dopachrome tautomerase OS=Sus scrofa OX=9823
GN=DCT PE=2 SV=1
Length=519
Score = 38.9 bits (89), Expect = 0.010, Method: Composition-based stats.
Identities = 24/94 (26%), Positives = 35/94 (37%), Gaps = 4/94 (4%)
Query 15 LLLSILGLAFLSEAAARKIPKVGHTF--FQKPESCPPVPGGSMKLDIGIINENQRVSMSR 72
LLL LG A L A + P+V T Q E CPP+ + + + +
Sbjct 8 LLLGCLGSA-LGPGAQAQFPRVCMTVGSLQAKECCPPLGAEPSNVCGSLEGRGRCAEVQA 66
Query 73 NIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLG 106
+ S P+ D R+P + CR G
Sbjct 67 DTRPWS-GPYVLRNQDDRERWPRKFFDRTCRCTG 99
>sp|Q22687|IL171_CAEEL Interleukin cytokine-related protein 17.1
OS=Caenorhabditis elegans OX=6239 GN=ilc-17.1 PE=1 SV=2
Length=221
Score = 35.8 bits (81), Expect = 0.093, Method: Composition-based stats.
Identities = 14/72 (19%), Positives = 26/72 (36%), Gaps = 13/72 (18%)
Query 35 KVGHTFFQKPESCPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYP 94
K G + C S KLD +S + R+ + Y + ++P R P
Sbjct 94 KHGEQITKSSGKC-----NSKKLD--------TISAETPLRDRALCKFEYVLNYNPKRLP 140
Query 95 SEVVQAQCRNLG 106
+ + + +C
Sbjct 141 AALTEVKCSCPR 152
>sp|Q95119|TYRP2_BOVIN L-dopachrome tautomerase OS=Bos taurus
OX=9913 GN=DCT PE=2 SV=2
Length=517
Score = 35.8 bits (81), Expect = 0.14, Method: Composition-based stats.
Identities = 18/82 (22%), Positives = 27/82 (33%), Gaps = 3/82 (4%)
Query 27 EAAARKIPKVGHTF--FQKPESCPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNY 84
A + P+V T Q E CPP+ + Q + + S P+
Sbjct 19 SGARAQFPRVCMTVGSLQAKECCPPLGADPANVCGSREGRGQCAEVQTDTRPWS-GPYVL 77
Query 85 TVTWDPNRYPSEVVQAQCRNLG 106
D R+P + CR G
Sbjct 78 RNQDDRERWPRKFFDRTCRCTG 99
>sp|Q5NL15|PANC_ZYMMO Pantothenate synthetase OS=Zymomonas mobilis
subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) OX=264203
GN=panC PE=3 SV=2
Length=287
Score = 33.9 bits (76), Expect = 0.42, Method: Composition-based stats.
Identities = 16/88 (18%), Positives = 33/88 (38%), Gaps = 10/88 (11%)
Query 66 QRVSMSRNIESRST--SPWNYTVTWDPNRYPSEVVQ--AQCRNLGC------INAQGKED 115
Q+ ++ S +P + V D + YP ++ A C+ G A+ +
Sbjct 42 QKAREESDVVVLSIFVNPIQFGVNEDLDVYPRDLPHDIALCKENGVDIIFAPSVAEIYPE 101
Query 116 ISMNSVPIQQETLVVRRKHQGCSVSFQL 143
M SV +Q + ++ +H+
Sbjct 102 PIMTSVEVQSLSNILIGRHRPNHFRGVT 129
Lambda K H a alpha
0.318 0.132 0.384 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0404 0.140 1.90 42.6 43.6
Effective search space used: 7798067532
Database: uniprot_sprot.fasta
Posted date: Apr 3, 2024 12:05 PM
Number of letters in database: 206,678,396
Number of sequences in database: 571,282
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40