HOMCOS : Searching and Modeling of 3D Structures of Complexes

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Services		Queries	Descriptions
Searching Contact Molecules	Searching Contact Molecules for Query Protein	Sequence	Search contact molecules with similar proteins to a given query sequence
	Searching Contact Proteins for Query Compound	Compound	Search contact proteins with similar compounds to a given query compounds
Modeling Complex 3D Structure	Homo Protein Multimer	Sequence	Model 3D structure of homo-multimer for one given sequence using homology-modeling technique.
	Hetero Protein Multimer	Two Sequences	Model 3D structure of hetero-multimer for two given sequence using homology-modeling technique.
	Protein-Compound Complex	Sequence and Compound	Model 3D structure of protein-compound complex for one given sequence and one given chemical structure using homology-modeling technique.

HOMCOS is developed and maintained by Protein Data Bank Japan, IPR, Osaka University. It is now supported by the project "Platform for Drug Discovery, Informatics, and Structural Life Science" by MEXT, Japan.

This server is based on the concept of HOMCOS server developed by NAIST.

A part of the services of the HOMCOS server can be accessed by VaProS server. HOMCOS is called "3D Interaction" in the VaProS server.

References

• Kawabata T. (2016) HOMCOS: an update server to search and model complex 3D structures. J.Struct.Funct.Genomics. 17,83-99. [PubMed] [Publisher]
• Fukuhara N., Kawabata T. (2008) HOMCOS: a server to predict interacting protein pairs and interacting sites by homology modeling of complex structures. Nucleic Acids Res., 36, W185-W189. [PubMed]