HOMCOS(prot_sch_conbars.cgi):

		Contact Molecules for Homologous Proteins
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PID

QueryLength

Homolgous Sequence in PDB

UniProt Query

TITLE

22598

425

P84022(SMAD3_HUMAN)

RecName: Full=Mothers against decapentaplegic homolog 3; Short=MAD homolog 3; Short=Mad3; Short=Mothers against DPP homolog 3; Short=hMAD-3;AltName: Full=JV15-2;AltName: Full=SMAD family member 3; Short=SMAD 3; Short=Smad3; Short=hSMAD3;

QUERYSEQ

MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEF
PPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG
GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS

[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]

UniProt Feature Tables [P84022(SMAD3_HUMAN)]

425
	region	name	description
	2-425	CHAIN	/note="Mothers against decapentaplegic homolog 3" /id="PRO_0000090856"
	10-136	DOMAIN	/note="MH1"
	232-425	DOMAIN	/note="MH2"
	137-231	REGION	/note="Linker"
	165-208	REGION	/note="Disordered"
	271-324	REGION	/note="Sufficient for interaction with XPO4"
	64-64	BINDING	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105"
	109-109	BINDING	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105"
	121-121	BINDING	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105"
	126-126	BINDING	/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105"
	1-425	DISORDER	predicted by DISOPRED

MONOMER

425

pdb_id a¹ identity[%]² description

1mk2 A 100.0 SMAD3_HUMAN SMAD 3

6m64 A 96.0 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

1khx A 96.5 SMAD2_HUMAN Smad2

1u7f A 100.0 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

6zvq A 96.5 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5xoc A 100.0 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

1u7f C 100.0 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

1u7v A 96.9 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

1dev A 97.4 SMAD2_HUMAN MAD (mothers against decapentaplegic, Drosophila) homolog 2

1u7v B 96.9 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

7co1 A 97.4 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6m64 C 97.4 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

7co1 C 97.4 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6m64 E 97.4 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

7co1 E 97.4 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

1dev C 97.4 SMAD2_HUMAN MAD (mothers against decapentaplegic, Drosophila) homolog 2

5xod A 97.4 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5zoj A 97.9 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5zoj C 97.8 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5zoj B 97.8 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

1mjs A 100.0 SMAD3_HUMAN SMAD 3

1ozj C 100.0 SMAD3_HUMAN SMAD 3

5odg A 100.0 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5od6 B 100.0 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5odg B 100.0 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5od6 A 100.0 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

1ozj D 100.0 SMAD3_HUMAN SMAD 3

1mhd D 100.0 SMAD3_HUMAN SMAD3

1mhd C 100.0 SMAD3_HUMAN SMAD3

6zmn A 96.7 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

6zmn B 96.6 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

1.a¹:asym_id for the homologue. 2.identity[%]²:sequence identity between the query and the homologue.

HETERO

425 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

1dev B ZFYV9_HUMAN Smad anchor for receptor activation[41 aa] A 100.0
/97.4 31
/31 SMAD2_HUMAN MAD (mothers against decapentaplegic, Drosophila) ..

1dev D ZFYV9_HUMAN Smad anchor for receptor activation[39 aa] C 100.0
/97.4 32
/32 SMAD2_HUMAN MAD (mothers against decapentaplegic, Drosophila) ..

1mk2 B ZFYV9_HUMAN Madh-interacting protein[38 aa] A 100.0
/100.0 31
/31 SMAD3_HUMAN SMAD 3

1mk2 B ZFYV9_HUMAN Madh-interacting protein[38 aa] A 100.0
/100.0 31
/31 SMAD3_HUMAN SMAD 3

5xoc B THIO_ECOLI FOXH1_HUMAN Thioredoxin 1,Forkhead box protein H1[133 aa] A 100.0
/100.0 26
/26 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5xoc B THIO_ECOLI FOXH1_HUMAN Thioredoxin 1,Forkhead box protein H1[133 aa] A 100.0
/100.0 26
/26 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5xoc B THIO_ECOLI FOXH1_HUMAN Thioredoxin 1,Forkhead box protein H1[133 aa] A 100.0
/100.0 26
/26 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5zoj D MAN1_HUMAN Inner nuclear membrane protein Man1[127 aa] A 100.0
/97.9 12
/12 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5zoj E MAN1_HUMAN Inner nuclear membrane protein Man1[116 aa] B 100.0
/97.8 15
/15 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6m64 B CBP[19 aa] A 100.0
/96.0 11
/11 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6m64 D CBP[20 aa] C 100.0
/97.4 15
/15 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6m64 F CBP[27 aa] E 100.0
/97.4 16
/16 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

7co1 B CBP_HUMAN CREB-binding protein[20 aa] A 100.0
/97.4 12
/12 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

7co1 D CBP_HUMAN CREB-binding protein[20 aa] C 100.0
/97.4 13
/13 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

7co1 F CBP_HUMAN CREB-binding protein[18 aa] E 100.0
/97.4 14
/14 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

1u7f B SMAD4_HUMAN Mothers against decapentaplegic homolog 4[193 aa] A 96.3
/100.0 27
/28 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

1u7f B SMAD4_HUMAN Mothers against decapentaplegic homolog 4[193 aa] C 100.0
/100.0 20
/20 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

1u7v C SMAD4_HUMAN Mothers against decapentaplegic homolog 4[208 aa] A 88.5
/96.9 26
/27 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

1u7v C SMAD4_HUMAN Mothers against decapentaplegic homolog 4[208 aa] B 100.0
/96.9 19
/19 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5xod B SKI_HUMAN Ski oncogene[22 aa] A 100.0
/97.4 20
/20 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5xod B SKI_HUMAN Ski oncogene[22 aa] A 100.0
/97.4 20
/20 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5xod B SKI_HUMAN Ski oncogene[22 aa] A 100.0
/97.4 20
/20 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq B SKI_HUMAN Ski oncogene[27 aa] A 95.0
/96.5 20
/20 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq B SKI_HUMAN Ski oncogene[27 aa] A 95.0
/96.5 20
/20 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq B SKI_HUMAN Ski oncogene[27 aa] A 95.0
/96.5 20
/20 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

NUCLEOTIDE

425 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

1mhd A DNA C 100.0
/100.0 9
/9 SMAD3_HUMAN SMAD3

1mhd A DNA D 100.0
/100.0 3
/3 SMAD3_HUMAN SMAD3

1mhd B DNA C 100.0
/100.0 4
/4 SMAD3_HUMAN SMAD3

1mhd B DNA D 100.0
/100.0 7
/7 SMAD3_HUMAN SMAD3

1ozj A Smad binding element C 100.0
/100.0 10
/10 SMAD3_HUMAN SMAD 3

1ozj A Smad binding element D 100.0
/100.0 3
/3 SMAD3_HUMAN SMAD 3

1ozj B Smad binding element C 100.0
/100.0 6
/6 SMAD3_HUMAN SMAD 3

1ozj B Smad binding element D 100.0
/100.0 9
/9 SMAD3_HUMAN SMAD 3

5odg C DNA (5'-D(P*CP*AP*GP*GP*CP*TP*AP*GP*CP*CP*TP*GP*CP.. A 100.0
/100.0 8
/8 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5odg C DNA (5'-D(P*CP*AP*GP*GP*CP*TP*AP*GP*CP*CP*TP*GP*CP.. A 100.0
/100.0 8
/8 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5odg C DNA (5'-D(P*CP*AP*GP*GP*CP*TP*AP*GP*CP*CP*TP*GP*CP.. B 100.0
/100.0 3
/3 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5odg C DNA (5'-D(P*CP*AP*GP*GP*CP*TP*AP*GP*CP*CP*TP*GP*CP.. B 100.0
/100.0 3
/3 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5odg D DNA (5'-D(P*CP*AP*GP*GP*CP*TP*AP*GP*CP*CP*TP*GP*CP.. A 100.0
/100.0 5
/5 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5odg D DNA (5'-D(P*CP*AP*GP*GP*CP*TP*AP*GP*CP*CP*TP*GP*CP.. A 100.0
/100.0 5
/5 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5odg D DNA (5'-D(P*CP*AP*GP*GP*CP*TP*AP*GP*CP*CP*TP*GP*CP.. B 100.0
/100.0 11
/11 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5odg D DNA (5'-D(P*CP*AP*GP*GP*CP*TP*AP*GP*CP*CP*TP*GP*CP.. B 100.0
/100.0 11
/11 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5od6 C DNA (5'-D(P*TP*GP*CP*AP*GP*GP*CP*GP*CP*GP*CP*CP*TP.. A 100.0
/100.0 5
/5 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5od6 D DNA (5'-D(P*TP*GP*CP*AP*GP*GP*CP*GP*CP*GP*CP*CP*TP.. A 100.0
/100.0 9
/9 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

6zmn C DNA (5'-D(P*TP*GP*CP*AP*GP*GP*CP*GP*CP*GP*CP*CP*TP.. A 100.0
/96.7 3
/3 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

6zmn D DNA (5'-D(P*TP*GP*CP*AP*GP*GP*CP*GP*CP*GP*CP*CP*TP.. A 100.0
/96.7 8
/8 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

6zmn C DNA (5'-D(P*TP*GP*CP*AP*GP*GP*CP*GP*CP*GP*CP*CP*TP.. B 100.0
/96.6 8
/8 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

6zmn D DNA (5'-D(P*TP*GP*CP*AP*GP*GP*CP*GP*CP*GP*CP*CP*TP.. B 100.0
/96.6 6
/6 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

COMPOUND

425 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

6zvq I TAR
D(-)-TARTARIC ACID[10 atoms] A 100.0
/96.5 2
/2 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq I TAR
D(-)-TARTARIC ACID[10 atoms] A 100.0
/96.5 2
/2 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq I TAR
D(-)-TARTARIC ACID[10 atoms] A 100.0
/96.5 2
/2 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq J TAR
D(-)-TARTARIC ACID[10 atoms] A 100.0
/96.5 4
/4 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq J TAR
D(-)-TARTARIC ACID[10 atoms] A 100.0
/96.5 6
/6 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq J TAR
D(-)-TARTARIC ACID[10 atoms] A 100.0
/96.5 4
/4 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq J TAR
D(-)-TARTARIC ACID[10 atoms] A 100.0
/96.5 6
/6 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq J TAR
D(-)-TARTARIC ACID[10 atoms] A 100.0
/96.5 6
/6 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq J TAR
D(-)-TARTARIC ACID[10 atoms] A 100.0
/96.5 4
/4 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq O TAR
D(-)-TARTARIC ACID[10 atoms] A 100.0
/96.5 4
/4 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq O TAR
D(-)-TARTARIC ACID[10 atoms] A 100.0
/96.5 4
/4 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq O TAR
D(-)-TARTARIC ACID[10 atoms] A 100.0
/96.5 4
/4 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

METAL

425 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

5odg F CL
CHLORIDE ION[1 atoms] A 100.0
/100.0 1
/1 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5odg F CL
CHLORIDE ION[1 atoms] A 100.0
/100.0 1
/1 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

1ozj E ZN
ZINC ION[1 atoms] C 100.0
/100.0 4
/4 SMAD3_HUMAN SMAD 3

1ozj F ZN
ZINC ION[1 atoms] D 100.0
/100.0 4
/4 SMAD3_HUMAN SMAD 3

5od6 E ZN
ZINC ION[1 atoms] A 100.0
/100.0 4
/4 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5od6 F ZN
ZINC ION[1 atoms] B 100.0
/100.0 4
/4 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5odg E ZN
ZINC ION[1 atoms] A 100.0
/100.0 4
/4 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5odg E ZN
ZINC ION[1 atoms] A 100.0
/100.0 4
/4 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5odg G ZN
ZINC ION[1 atoms] B 100.0
/100.0 4
/4 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5odg G ZN
ZINC ION[1 atoms] B 100.0
/100.0 4
/4 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

6zmn G ZN
ZINC ION[1 atoms] A 100.0
/96.7 4
/4 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

6zmn I ZN
ZINC ION[1 atoms] B 100.0
/96.6 4
/4 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

HOMO

425 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

1khx A SMAD2_HUMAN Smad2[203 aa] A 96.3
/96.5 27
/27 SMAD2_HUMAN Smad2

1khx A SMAD2_HUMAN Smad2[203 aa] A 86.7
/96.5 30
/31 SMAD2_HUMAN Smad2

1khx A SMAD2_HUMAN Smad2[203 aa] A 86.7
/96.5 30
/31 SMAD2_HUMAN Smad2

1khx A SMAD2_HUMAN Smad2[203 aa] A 96.3
/96.5 27
/27 SMAD2_HUMAN Smad2

1khx A SMAD2_HUMAN Smad2[203 aa] A 96.3
/96.5 27
/27 SMAD2_HUMAN Smad2

1khx A SMAD2_HUMAN Smad2[203 aa] A 86.7
/96.5 30
/31 SMAD2_HUMAN Smad2

1mk2 A SMAD3_HUMAN SMAD 3[197 aa] A 100.0
/100.0 12
/12 SMAD3_HUMAN SMAD 3

1mk2 A SMAD3_HUMAN SMAD 3[197 aa] A 100.0
/100.0 12
/12 SMAD3_HUMAN SMAD 3

1u7f C SMAD3_HUMAN Mothers against decapentaplegic homolog 3[196 aa] A 100.0
/100.0 23
/23 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

1u7f A SMAD3_HUMAN Mothers against decapentaplegic homolog 3[198 aa] C 95.7
/100.0 23
/24 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

1u7v B SMAD2_HUMAN Mothers against decapentaplegic homolog 2[196 aa] A 100.0
/96.9 21
/21 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

1u7v A SMAD2_HUMAN Mothers against decapentaplegic homolog 2[198 aa] B 87.5
/96.9 24
/25 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5xoc A SMAD3_HUMAN Mothers against decapentaplegic homolog 3[194 aa] A 100.0
/100.0 17
/17 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5xoc A SMAD3_HUMAN Mothers against decapentaplegic homolog 3[194 aa] A 100.0
/100.0 14
/14 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5xoc A SMAD3_HUMAN Mothers against decapentaplegic homolog 3[194 aa] A 100.0
/100.0 14
/14 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5xoc A SMAD3_HUMAN Mothers against decapentaplegic homolog 3[194 aa] A 100.0
/100.0 17
/17 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5xoc A SMAD3_HUMAN Mothers against decapentaplegic homolog 3[194 aa] A 100.0
/100.0 17
/17 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5xoc A SMAD3_HUMAN Mothers against decapentaplegic homolog 3[194 aa] A 100.0
/100.0 14
/14 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5xod A SMAD2_HUMAN Mothers against decapentaplegic homolog 2[193 aa] A 100.0
/97.4 20
/20 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5xod A SMAD2_HUMAN Mothers against decapentaplegic homolog 2[193 aa] A 96.0
/97.4 25
/25 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5xod A SMAD2_HUMAN Mothers against decapentaplegic homolog 2[193 aa] A 96.0
/97.4 25
/25 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5xod A SMAD2_HUMAN Mothers against decapentaplegic homolog 2[193 aa] A 100.0
/97.4 20
/20 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5xod A SMAD2_HUMAN Mothers against decapentaplegic homolog 2[193 aa] A 100.0
/97.4 20
/20 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5xod A SMAD2_HUMAN Mothers against decapentaplegic homolog 2[193 aa] A 96.0
/97.4 25
/25 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5zoj B SMAD2_HUMAN Mothers against decapentaplegic homolog 2[185 aa] A 100.0
/97.9 14
/14 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5zoj C SMAD2_HUMAN Mothers against decapentaplegic homolog 2[186 aa] A 100.0
/97.9 17
/17 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5zoj A SMAD2_HUMAN Mothers against decapentaplegic homolog 2[187 aa] B 100.0
/97.8 16
/16 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5zoj C SMAD2_HUMAN Mothers against decapentaplegic homolog 2[186 aa] B 100.0
/97.8 15
/15 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5zoj A SMAD2_HUMAN Mothers against decapentaplegic homolog 2[187 aa] C 100.0
/97.8 12
/12 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

5zoj B SMAD2_HUMAN Mothers against decapentaplegic homolog 2[185 aa] C 100.0
/97.8 18
/18 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6m64 C SMAD2_HUMAN Mothers against decapentaplegic homolog 2[194 aa] A 100.0
/96.0 15
/15 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6m64 E SMAD2_HUMAN Mothers against decapentaplegic homolog 2[193 aa] A 87.9
/96.0 33
/34 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6m64 A SMAD2_HUMAN Mothers against decapentaplegic homolog 2[203 aa] C 96.2
/97.4 26
/26 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6m64 E SMAD2_HUMAN Mothers against decapentaplegic homolog 2[193 aa] C 100.0
/97.4 15
/15 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6m64 A SMAD2_HUMAN Mothers against decapentaplegic homolog 2[203 aa] E 96.7
/97.4 30
/30 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6m64 C SMAD2_HUMAN Mothers against decapentaplegic homolog 2[194 aa] E 96.2
/97.4 26
/26 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq A SMAD2_HUMAN Mothers against decapentaplegic homolog 2[202 aa] A 100.0
/96.5 27
/27 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq A SMAD2_HUMAN Mothers against decapentaplegic homolog 2[202 aa] A 87.5
/96.5 32
/33 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq A SMAD2_HUMAN Mothers against decapentaplegic homolog 2[202 aa] A 87.5
/96.5 32
/33 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq A SMAD2_HUMAN Mothers against decapentaplegic homolog 2[202 aa] A 100.0
/96.5 27
/27 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq A SMAD2_HUMAN Mothers against decapentaplegic homolog 2[202 aa] A 100.0
/96.5 27
/27 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq A SMAD2_HUMAN Mothers against decapentaplegic homolog 2[202 aa] A 87.5
/96.5 32
/33 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

7co1 C SMAD2_HUMAN Mothers against decapentaplegic homolog 2[193 aa] A 100.0
/97.4 15
/15 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

7co1 E SMAD2_HUMAN Mothers against decapentaplegic homolog 2[192 aa] A 95.2
/97.4 21
/21 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

7co1 A SMAD2_HUMAN Mothers against decapentaplegic homolog 2[194 aa] C 95.8
/97.4 24
/24 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

7co1 E SMAD2_HUMAN Mothers against decapentaplegic homolog 2[192 aa] C 100.0
/97.4 15
/15 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

7co1 A SMAD2_HUMAN Mothers against decapentaplegic homolog 2[194 aa] E 100.0
/97.4 14
/14 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

7co1 C SMAD2_HUMAN Mothers against decapentaplegic homolog 2[193 aa] E 95.0
/97.4 20
/20 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

1ozj D SMAD3_HUMAN SMAD 3[124 aa] C 100.0
/100.0 1
/1 SMAD3_HUMAN SMAD 3

1ozj C SMAD3_HUMAN SMAD 3[126 aa] D 100.0
/100.0 1
/1 SMAD3_HUMAN SMAD 3

5od6 B SMAD3_HUMAN Mothers against decapentaplegic homolog 3[126 aa] A 100.0
/100.0 5
/5 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

5od6 A SMAD3_HUMAN Mothers against decapentaplegic homolog 3[125 aa] B 100.0
/100.0 8
/8 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

6zmn B SMAD3_HUMAN Mothers against decapentaplegic homolog 3[119 aa] A 88.5
/96.7 26
/26 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

6zmn A SMAD3_HUMAN Mothers against decapentaplegic homolog 3[120 aa] B 91.3
/96.6 23
/23 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

PRECIPITANT

425 pdb_id contact mol homologue

a³ description a⁴ identity[%]⁵ Ncon⁶ description

1mk2 C ACY
ACETIC ACID[4 atoms] A 100.0
/100.0 6
/6 SMAD3_HUMAN SMAD 3

1mk2 C ACY
ACETIC ACID[4 atoms] A 100.0
/100.0 6
/6 SMAD3_HUMAN SMAD 3

1mk2 D ACY
ACETIC ACID[4 atoms] A 100.0
/100.0 6
/6 SMAD3_HUMAN SMAD 3

1mk2 D ACY
ACETIC ACID[4 atoms] A 100.0
/100.0 2
/2 SMAD3_HUMAN SMAD 3

1mk2 D ACY
ACETIC ACID[4 atoms] A 100.0
/100.0 2
/2 SMAD3_HUMAN SMAD 3

1mk2 D ACY
ACETIC ACID[4 atoms] A 100.0
/100.0 6
/6 SMAD3_HUMAN SMAD 3

1mk2 E ACY
ACETIC ACID[4 atoms] A 100.0
/100.0 3
/3 SMAD3_HUMAN SMAD 3

1mk2 E ACY
ACETIC ACID[4 atoms] A 100.0
/100.0 3
/3 SMAD3_HUMAN SMAD 3

1mk2 F ACY
ACETIC ACID[4 atoms] A 100.0
/100.0 4
/4 SMAD3_HUMAN SMAD 3

1mk2 F ACY
ACETIC ACID[4 atoms] A 100.0
/100.0 4
/4 SMAD3_HUMAN SMAD 3

6zmn E ACT
ACETATE ION[4 atoms] A 100.0
/96.7 3
/3 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

6zmn F EDO
1,2-ETHANEDIOL[4 atoms] A 100.0
/96.7 6
/6 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

6zmn H PGE
TRIETHYLENE GLYCOL[10 atoms] B 66.7
/96.6 3
/3 SMAD3_HUMAN Mothers against decapentaplegic homolog 3

6zvq C SO4
SULFATE ION[5 atoms] A 100.0
/96.5 7
/7 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq C SO4
SULFATE ION[5 atoms] A 100.0
/96.5 7
/7 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq C SO4
SULFATE ION[5 atoms] A 100.0
/96.5 7
/7 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq D SO4
SULFATE ION[5 atoms] A 100.0
/96.5 5
/5 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq D SO4
SULFATE ION[5 atoms] A 100.0
/96.5 5
/5 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq D SO4
SULFATE ION[5 atoms] A 100.0
/96.5 5
/5 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq E GOL
GLYCEROL[6 atoms] A 100.0
/96.5 7
/7 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq E GOL
GLYCEROL[6 atoms] A 100.0
/96.5 7
/7 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq E GOL
GLYCEROL[6 atoms] A 100.0
/96.5 7
/7 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq F GOL
GLYCEROL[6 atoms] A 100.0
/96.5 5
/5 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq F GOL
GLYCEROL[6 atoms] A 100.0
/96.5 1
/1 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq F GOL
GLYCEROL[6 atoms] A 100.0
/96.5 1
/1 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq F GOL
GLYCEROL[6 atoms] A 100.0
/96.5 5
/5 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq F GOL
GLYCEROL[6 atoms] A 100.0
/96.5 1
/1 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq F GOL
GLYCEROL[6 atoms] A 100.0
/96.5 5
/5 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq G GOL
GLYCEROL[6 atoms] A 100.0
/96.5 4
/4 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq G GOL
GLYCEROL[6 atoms] A 100.0
/96.5 4
/4 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq G GOL
GLYCEROL[6 atoms] A 100.0
/96.5 4
/4 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq H GOL
GLYCEROL[6 atoms] A 100.0
/96.5 3
/3 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq H GOL
GLYCEROL[6 atoms] A 0.0
/96.5 1
/1 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq H GOL
GLYCEROL[6 atoms] A 0.0
/96.5 1
/1 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq H GOL
GLYCEROL[6 atoms] A 100.0
/96.5 3
/3 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq H GOL
GLYCEROL[6 atoms] A 0.0
/96.5 1
/1 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq H GOL
GLYCEROL[6 atoms] A 100.0
/96.5 3
/3 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq K GOL
GLYCEROL[6 atoms] A 100.0
/96.5 6
/6 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq K GOL
GLYCEROL[6 atoms] A 100.0
/96.5 6
/6 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq K GOL
GLYCEROL[6 atoms] A 100.0
/96.5 6
/6 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq L GOL
GLYCEROL[6 atoms] A 100.0
/96.5 4
/4 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq L GOL
GLYCEROL[6 atoms] A 80.0
/96.5 5
/5 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq L GOL
GLYCEROL[6 atoms] A 80.0
/96.5 5
/5 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq L GOL
GLYCEROL[6 atoms] A 100.0
/96.5 4
/4 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq L GOL
GLYCEROL[6 atoms] A 80.0
/96.5 5
/5 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq L GOL
GLYCEROL[6 atoms] A 100.0
/96.5 4
/4 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq M GOL
GLYCEROL[6 atoms] A 100.0
/96.5 3
/3 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq M GOL
GLYCEROL[6 atoms] A 100.0
/96.5 3
/3 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq M GOL
GLYCEROL[6 atoms] A 100.0
/96.5 3
/3 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq N GOL
GLYCEROL[6 atoms] A 100.0
/96.5 2
/2 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq N GOL
GLYCEROL[6 atoms] A 100.0
/96.5 2
/2 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

6zvq N GOL
GLYCEROL[6 atoms] A 100.0
/96.5 2
/2 SMAD2_HUMAN Mothers against decapentaplegic homolog 2

3.a³:asym_id for the contact molecule. 4.a⁴:asym_id for the template homologue. 5.identity[%]⁵:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon⁶:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.

MONOMER
425
	pdb_id	a¹	identity[%]²	description
	1mk2	A	100.0	SMAD3_HUMAN SMAD 3
	6m64	A	96.0	SMAD2_HUMAN Mothers against decapentaplegic homolog 2
	1khx	A	96.5	SMAD2_HUMAN Smad2
	1u7f	A	100.0	SMAD3_HUMAN Mothers against decapentaplegic homolog 3
	6zvq	A	96.5	SMAD2_HUMAN Mothers against decapentaplegic homolog 2
	5xoc	A	100.0	SMAD3_HUMAN Mothers against decapentaplegic homolog 3
	1u7f	C	100.0	SMAD3_HUMAN Mothers against decapentaplegic homolog 3
	1u7v	A	96.9	SMAD2_HUMAN Mothers against decapentaplegic homolog 2
	1dev	A	97.4	SMAD2_HUMAN MAD (mothers against decapentaplegic, Drosophila) homolog 2
	1u7v	B	96.9	SMAD2_HUMAN Mothers against decapentaplegic homolog 2
	7co1	A	97.4	SMAD2_HUMAN Mothers against decapentaplegic homolog 2
	6m64	C	97.4	SMAD2_HUMAN Mothers against decapentaplegic homolog 2
	7co1	C	97.4	SMAD2_HUMAN Mothers against decapentaplegic homolog 2
	6m64	E	97.4	SMAD2_HUMAN Mothers against decapentaplegic homolog 2
	7co1	E	97.4	SMAD2_HUMAN Mothers against decapentaplegic homolog 2
	1dev	C	97.4	SMAD2_HUMAN MAD (mothers against decapentaplegic, Drosophila) homolog 2
	5xod	A	97.4	SMAD2_HUMAN Mothers against decapentaplegic homolog 2
	5zoj	A	97.9	SMAD2_HUMAN Mothers against decapentaplegic homolog 2
	5zoj	C	97.8	SMAD2_HUMAN Mothers against decapentaplegic homolog 2
	5zoj	B	97.8	SMAD2_HUMAN Mothers against decapentaplegic homolog 2
	1mjs	A	100.0	SMAD3_HUMAN SMAD 3
	1ozj	C	100.0	SMAD3_HUMAN SMAD 3
	5odg	A	100.0	SMAD3_HUMAN Mothers against decapentaplegic homolog 3
	5od6	B	100.0	SMAD3_HUMAN Mothers against decapentaplegic homolog 3
	5odg	B	100.0	SMAD3_HUMAN Mothers against decapentaplegic homolog 3
	5od6	A	100.0	SMAD3_HUMAN Mothers against decapentaplegic homolog 3
	1ozj	D	100.0	SMAD3_HUMAN SMAD 3
	1mhd	D	100.0	SMAD3_HUMAN SMAD3
	1mhd	C	100.0	SMAD3_HUMAN SMAD3
	6zmn	A	96.7	SMAD3_HUMAN Mothers against decapentaplegic homolog 3
	6zmn	B	96.6	SMAD3_HUMAN Mothers against decapentaplegic homolog 3
	1.a¹:asym_id for the homologue. 2.identity[%]²:sequence identity between the query and the homologue.

Contact Molecules for Homologous Proteins

Full Bars[90 %]

UniProt Feature Tables [P84022(SMAD3_HUMAN)]