PSIBLAST 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Stephen F.
Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005)
"Protein database searches using compositionally adjusted
substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: uniprot_sprot.fasta
571,282 sequences; 206,678,396 total letters
Results from round 1
Query= sp|P84022|SMAD3_HUMAN Mothers against decapentaplegic homolog 3
OS=Homo sapiens OX=9606 GN=SMAD3 PE=1 SV=1
Length=425
Score E
Sequences producing significant alignments: (Bits) Value
sp|P84025|SMAD3_RAT Mothers against decapentaplegic homolog 3 OS=... 890 0.0
sp|P84024|SMAD3_PIG Mothers against decapentaplegic homolog 3 OS=... 890 0.0
sp|Q8BUN5|SMAD3_MOUSE Mothers against decapentaplegic homolog 3 O... 890 0.0
sp|P84022|SMAD3_HUMAN Mothers against decapentaplegic homolog 3 O... 890 0.0
sp|P84023|SMAD3_CHICK Mothers against decapentaplegic homolog 3 O... 880 0.0
sp|Q62432|SMAD2_MOUSE Mothers against decapentaplegic homolog 2 O... 779 0.0
sp|Q15796|SMAD2_HUMAN Mothers against decapentaplegic homolog 2 O... 778 0.0
sp|O70436|SMAD2_RAT Mothers against decapentaplegic homolog 2 OS=... 777 0.0
sp|Q5R7C0|SMAD2_PONAB Mothers against decapentaplegic homolog 2 O... 777 0.0
sp|Q1W668|SMAD2_BOVIN Mothers against decapentaplegic homolog 2 O... 776 0.0
sp|Q9I9P9|SMAD2_DANRE Mothers against decapentaplegic homolog 2 O... 754 0.0
sp|P97454|SMAD5_MOUSE Mothers against decapentaplegic homolog 5 O... 546 0.0
sp|Q56I99|SMAD5_CHICK Mothers against decapentaplegic homolog 5 O... 545 0.0
sp|Q5R6H7|SMAD5_PONAB Mothers against decapentaplegic homolog 5 O... 544 0.0
sp|Q99717|SMAD5_HUMAN Mothers against decapentaplegic homolog 5 O... 544 0.0
sp|Q9W7E7|SMAD5_DANRE Mothers against decapentaplegic homolog 5 O... 542 0.0
sp|Q9R1V3|SMAD5_RAT Mothers against decapentaplegic homolog 5 OS=... 542 0.0
sp|P42003|MAD_DROME Protein mothers against dpp OS=Drosophila mel... 539 0.0
sp|Q15797|SMAD1_HUMAN Mothers against decapentaplegic homolog 1 O... 536 0.0
sp|Q9I962|SMAD1_COTJA Mothers against decapentaplegic homolog 1 O... 536 0.0
sp|Q1JQA2|SMAD1_BOVIN Mothers against decapentaplegic homolog 1 O... 536 0.0
sp|P97588|SMAD1_RAT Mothers against decapentaplegic homolog 1 OS=... 534 0.0
sp|Q9JIW5|SMAD9_MOUSE Mothers against decapentaplegic homolog 9 O... 533 0.0
sp|P70340|SMAD1_MOUSE Mothers against decapentaplegic homolog 1 O... 533 0.0
sp|O15198|SMAD9_HUMAN Mothers against decapentaplegic homolog 9 O... 529 0.0
sp|Q9I8V2|SMAD1_DANRE Mothers against decapentaplegic homolog 1 O... 525 0.0
sp|O54835|SMAD9_RAT Mothers against decapentaplegic homolog 9 OS=... 513 2e-180
sp|Q02330|SMA2_CAEEL Dwarfin sma-2 OS=Caenorhabditis elegans OX=6... 381 5e-129
sp|P45896|SMA3_CAEEL Dwarfin sma-3 OS=Caenorhabditis elegans OX=6... 295 1e-95
sp|P45897|SMA4_CAEEL Dwarfin sma-4 OS=Caenorhabditis elegans OX=6... 199 7e-57
sp|P97471|SMAD4_MOUSE Mothers against decapentaplegic homolog 4 O... 174 1e-47
sp|Q13485|SMAD4_HUMAN Mothers against decapentaplegic homolog 4 O... 174 2e-47
sp|O70437|SMAD4_RAT Mothers against decapentaplegic homolog 4 OS=... 174 2e-47
sp|Q9GKQ9|SMAD4_PIG Mothers against decapentaplegic homolog 4 OS=... 174 2e-47
sp|Q1HE26|SMAD4_BOVIN Mothers against decapentaplegic homolog 4 O... 174 2e-47
sp|Q21733|DAF8_CAEEL Smad protein daf-8 OS=Caenorhabditis elegans... 166 6e-45
sp|O43541|SMAD6_HUMAN Mothers against decapentaplegic homolog 6 O... 144 6e-37
sp|O35182|SMAD6_MOUSE Mothers against decapentaplegic homolog 6 O... 144 6e-37
sp|Q9W734|SMAD6_CHICK Mothers against decapentaplegic homolog 6 O... 131 6e-33
sp|O88406|SMAD7_RAT Mothers against decapentaplegic homolog 7 OS=... 115 5e-27
sp|O15105|SMAD7_HUMAN Mothers against decapentaplegic homolog 7 O... 115 5e-27
sp|O35253|SMAD7_MOUSE Mothers against decapentaplegic homolog 7 O... 114 1e-26
sp|F5GUE5|DAF14_CAEEL Smad-related protein daf-14 OS=Caenorhabdit... 105 4e-24
sp|Q95QI7|DAF3_CAEEL Smad protein daf-3 OS=Caenorhabditis elegans... 100 2e-21
sp|F4HXP9|MYO9_ARATH Myosin-9 OS=Arabidopsis thaliana OX=3702 GN=... 33.5 5.2
sp|Q9PMD4|G6PI_CAMJE Glucose-6-phosphate isomerase OS=Campylobact... 33.1 5.5
sp|A1A619|OCAD1_XENLA OCIA domain-containing protein 1 OS=Xenopus... 32.3 6.9
>sp|P84025|SMAD3_RAT Mothers against decapentaplegic homolog 3
OS=Rattus norvegicus OX=10116 GN=Smad3 PE=1 SV=1
Length=425
Score = 890 bits (2300), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 425/425 (100%), Positives = 425/425 (100%), Gaps = 0/425 (0%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60
MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV
Sbjct 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60
Query 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120
NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV
Sbjct 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120
Query 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP 180
CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP
Sbjct 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP 180
Query 181 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 240
PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL
Sbjct 181 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 240
Query 241 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 300
NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG
Sbjct 241 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 300
Query 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360
GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF
Sbjct 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360
Query 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420
EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR
Sbjct 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420
Query 421 CSSVS 425
CSSVS
Sbjct 421 CSSVS 425
>sp|P84024|SMAD3_PIG Mothers against decapentaplegic homolog 3
OS=Sus scrofa OX=9823 GN=SMAD3 PE=2 SV=1
Length=425
Score = 890 bits (2300), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 425/425 (100%), Positives = 425/425 (100%), Gaps = 0/425 (0%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60
MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV
Sbjct 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60
Query 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120
NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV
Sbjct 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120
Query 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP 180
CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP
Sbjct 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP 180
Query 181 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 240
PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL
Sbjct 181 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 240
Query 241 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 300
NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG
Sbjct 241 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 300
Query 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360
GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF
Sbjct 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360
Query 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420
EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR
Sbjct 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420
Query 421 CSSVS 425
CSSVS
Sbjct 421 CSSVS 425
>sp|Q8BUN5|SMAD3_MOUSE Mothers against decapentaplegic homolog
3 OS=Mus musculus OX=10090 GN=Smad3 PE=1 SV=2
Length=425
Score = 890 bits (2300), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 425/425 (100%), Positives = 425/425 (100%), Gaps = 0/425 (0%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60
MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV
Sbjct 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60
Query 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120
NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV
Sbjct 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120
Query 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP 180
CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP
Sbjct 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP 180
Query 181 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 240
PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL
Sbjct 181 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 240
Query 241 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 300
NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG
Sbjct 241 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 300
Query 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360
GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF
Sbjct 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360
Query 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420
EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR
Sbjct 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420
Query 421 CSSVS 425
CSSVS
Sbjct 421 CSSVS 425
>sp|P84022|SMAD3_HUMAN Mothers against decapentaplegic homolog
3 OS=Homo sapiens OX=9606 GN=SMAD3 PE=1 SV=1
Length=425
Score = 890 bits (2300), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 425/425 (100%), Positives = 425/425 (100%), Gaps = 0/425 (0%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60
MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV
Sbjct 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60
Query 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120
NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV
Sbjct 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120
Query 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP 180
CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP
Sbjct 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP 180
Query 181 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 240
PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL
Sbjct 181 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 240
Query 241 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 300
NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG
Sbjct 241 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 300
Query 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360
GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF
Sbjct 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360
Query 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420
EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR
Sbjct 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420
Query 421 CSSVS 425
CSSVS
Sbjct 421 CSSVS 425
>sp|P84023|SMAD3_CHICK Mothers against decapentaplegic homolog
3 OS=Gallus gallus OX=9031 GN=SMAD3 PE=2 SV=1
Length=426
Score = 880 bits (2273), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 421/426 (99%), Positives = 424/426 (99%), Gaps = 1/426 (0%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60
MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQN+
Sbjct 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNI 60
Query 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120
NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAME+CE+AFNMKKDEV
Sbjct 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMEMCEYAFNMKKDEV 120
Query 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPET 179
CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN IPET
Sbjct 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNYIPET 180
Query 180 PPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYE 239
PPPGYLSEDGETSDHQMN SMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYE
Sbjct 181 PPPGYLSEDGETSDHQMNPSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYE 240
Query 240 LNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYI 299
LNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYI
Sbjct 241 LNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYI 300
Query 300 GGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQG 359
GGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQG
Sbjct 301 GGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQG 360
Query 360 FEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSI 419
FEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSI
Sbjct 361 FEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSI 420
Query 420 RCSSVS 425
RCSSVS
Sbjct 421 RCSSVS 426
>sp|Q62432|SMAD2_MOUSE Mothers against decapentaplegic homolog
2 OS=Mus musculus OX=10090 GN=Smad2 PE=1 SV=2
Length=467
Score = 779 bits (2011), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 391/467 (84%), Positives = 410/467 (88%), Gaps = 42/467 (9%)
Query 1 MSSILPFTPPIVKRLLGWKKG----------EQNGQEEKWCEKAVKSLVKKLKKTGQLDE 50
MSSILPFTPP+VKRLLGWKK EQNGQEEKWCEKAVKSLVKKLKKTG+LDE
Sbjct 1 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60
Query 51 LEKAITTQNVNTKCITIP------------------------------RSLDGRLQVSHR 80
LEKAITTQN NTKC+TIP RSLDGRLQVSHR
Sbjct 61 LEKAITTQNCNTKCVTIPSTCSEIWGLSTANTVDQWDTTGLYSFSEQTRSLDGRLQVSHR 120
Query 81 KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLV 140
KGLPHVIYCRLWRWPDLHSHHEL+A+E CE+AFN+KKDEVCVNPYHYQRVETPVLPPVLV
Sbjct 121 KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV 180
Query 141 PRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHS 199
PRHTEI E PPLDDY+HSIPENTNFPAGIEPQSN IPETPPPGY+SEDGETSD Q+N S
Sbjct 181 PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQS 240
Query 200 MDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
MD GSP LSP +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS+TVD
Sbjct 241 MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVD 300
Query 259 GFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 318
GFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP
Sbjct 301 GFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 360
Query 319 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 378
NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK
Sbjct 361 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 420
Query 379 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct 421 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467
>sp|Q15796|SMAD2_HUMAN Mothers against decapentaplegic homolog
2 OS=Homo sapiens OX=9606 GN=SMAD2 PE=1 SV=1
Length=467
Score = 778 bits (2010), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 391/467 (84%), Positives = 410/467 (88%), Gaps = 42/467 (9%)
Query 1 MSSILPFTPPIVKRLLGWKKG----------EQNGQEEKWCEKAVKSLVKKLKKTGQLDE 50
MSSILPFTPP+VKRLLGWKK EQNGQEEKWCEKAVKSLVKKLKKTG+LDE
Sbjct 1 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60
Query 51 LEKAITTQNVNTKCITIP------------------------------RSLDGRLQVSHR 80
LEKAITTQN NTKC+TIP RSLDGRLQVSHR
Sbjct 61 LEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHR 120
Query 81 KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLV 140
KGLPHVIYCRLWRWPDLHSHHEL+A+E CE+AFN+KKDEVCVNPYHYQRVETPVLPPVLV
Sbjct 121 KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV 180
Query 141 PRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHS 199
PRHTEI E PPLDDY+HSIPENTNFPAGIEPQSN IPETPPPGY+SEDGETSD Q+N S
Sbjct 181 PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQS 240
Query 200 MDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
MD GSP LSP +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS+TVD
Sbjct 241 MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVD 300
Query 259 GFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 318
GFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP
Sbjct 301 GFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 360
Query 319 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 378
NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK
Sbjct 361 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 420
Query 379 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct 421 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467
>sp|O70436|SMAD2_RAT Mothers against decapentaplegic homolog 2
OS=Rattus norvegicus OX=10116 GN=Smad2 PE=1 SV=1
Length=467
Score = 777 bits (2006), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 390/467 (84%), Positives = 410/467 (88%), Gaps = 42/467 (9%)
Query 1 MSSILPFTPPIVKRLLGWKKG----------EQNGQEEKWCEKAVKSLVKKLKKTGQLDE 50
MSSILPFTPP+VKRLLGWKK EQNGQEEKWCEKAVKSLVKKLKKTG+LDE
Sbjct 1 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60
Query 51 LEKAITTQNVNTKCITIP------------------------------RSLDGRLQVSHR 80
LEKAITTQN NTKC+TIP RSLDGRLQVSHR
Sbjct 61 LEKAITTQNCNTKCVTIPSTCSEIWGLSTANTVDQWDTTGLYSFSEQTRSLDGRLQVSHR 120
Query 81 KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLV 140
KGLPHVIYCRLWRWPDLHSHHEL+A+E CE+AF++KKDEVCVNPYHYQRVETPVLPPVLV
Sbjct 121 KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFSLKKDEVCVNPYHYQRVETPVLPPVLV 180
Query 141 PRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHS 199
PRHTEI E PPLDDY+HSIPENTNFPAGIEPQSN IPETPPPGY+SEDGETSD Q+N S
Sbjct 181 PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQS 240
Query 200 MDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
MD GSP LSP +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS+TVD
Sbjct 241 MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVD 300
Query 259 GFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 318
GFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP
Sbjct 301 GFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 360
Query 319 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 378
NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK
Sbjct 361 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 420
Query 379 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct 421 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467
>sp|Q5R7C0|SMAD2_PONAB Mothers against decapentaplegic homolog
2 OS=Pongo abelii OX=9601 GN=SMAD2 PE=2 SV=1
Length=467
Score = 777 bits (2006), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 390/467 (84%), Positives = 410/467 (88%), Gaps = 42/467 (9%)
Query 1 MSSILPFTPPIVKRLLGWKKG----------EQNGQEEKWCEKAVKSLVKKLKKTGQLDE 50
MSSILPFTPP+VKRLLGWKK EQNGQEEKWCEKAVKSLVKKLKKTG+LDE
Sbjct 1 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60
Query 51 LEKAITTQNVNTKCITIP------------------------------RSLDGRLQVSHR 80
LEKAITTQN NTKC+TIP RSLDGRLQVSHR
Sbjct 61 LEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHR 120
Query 81 KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLV 140
KGLPHVIYCRLWRWPDLHSHHEL+A+E CE+AFN+K+DEVCVNPYHYQRVETPVLPPVLV
Sbjct 121 KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKEDEVCVNPYHYQRVETPVLPPVLV 180
Query 141 PRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHS 199
PRHTEI E PPLDDY+HSIPENTNFPAGIEPQSN IPETPPPGY+SEDGETSD Q+N S
Sbjct 181 PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQS 240
Query 200 MDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
MD GSP LSP +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS+TVD
Sbjct 241 MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVD 300
Query 259 GFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 318
GFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP
Sbjct 301 GFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 360
Query 319 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 378
NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK
Sbjct 361 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 420
Query 379 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct 421 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467
>sp|Q1W668|SMAD2_BOVIN Mothers against decapentaplegic homolog
2 OS=Bos taurus OX=9913 GN=SMAD2 PE=2 SV=1
Length=467
Score = 776 bits (2003), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 390/467 (84%), Positives = 409/467 (88%), Gaps = 42/467 (9%)
Query 1 MSSILPFTPPIVKRLLGWKKG----------EQNGQEEKWCEKAVKSLVKKLKKTGQLDE 50
MSSILPFTPP+VKRLLGWKK EQNGQEEKWCEKAVKSLVKKLKKTG+LDE
Sbjct 1 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60
Query 51 LEKAITTQNVNTKCITIP------------------------------RSLDGRLQVSHR 80
LEKAITTQN NTKC+TIP RSLDGRLQVSHR
Sbjct 61 LEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHR 120
Query 81 KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLV 140
KGLPHVIYCRLWRWPDLHSHHEL+A+E CE+AFN+KKDEVCVNPYHYQRVETPVLPPVLV
Sbjct 121 KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV 180
Query 141 PRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHS 199
PRHTEI E PPLDDY+HSIPENTNFPAGIEPQSN IPETPPPGY+SEDGETSD Q+N S
Sbjct 181 PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQS 240
Query 200 MDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
MD GSP LSP +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS+TVD
Sbjct 241 MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVD 300
Query 259 GFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 318
GFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP
Sbjct 301 GFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 360
Query 319 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 378
NCNQRYGWHPATVCKIPPGCNLKIFNNQ FAALLAQSVNQGFEAVYQLTRMCTIRMSFVK
Sbjct 361 NCNQRYGWHPATVCKIPPGCNLKIFNNQGFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 420
Query 379 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct 421 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467
>sp|Q9I9P9|SMAD2_DANRE Mothers against decapentaplegic homolog
2 OS=Danio rerio OX=7955 GN=smad2 PE=2 SV=1
Length=468
Score = 754 bits (1948), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 381/468 (81%), Positives = 400/468 (85%), Gaps = 43/468 (9%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEE-----------KWCEKAVKSLVKKLKKTGQLD 49
MSSILPFTPP+VKRLLGWKK KWCEKAVKSLVKKLKKTGQLD
Sbjct 1 MSSILPFTPPVVKRLLGWKKSASGSSGAGGGGEQNGQEEKWCEKAVKSLVKKLKKTGQLD 60
Query 50 ELEKAITTQNVNTKCITIP------------------------------RSLDGRLQVSH 79
ELEKAITTQN NTKC+TIP RSLDGRLQVSH
Sbjct 61 ELEKAITTQNRNTKCVTIPSNCSEIWGLSTPNTIEQWDTSGLYSYPDQTRSLDGRLQVSH 120
Query 80 RKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVL 139
RKGLPHVIYCRLWRWPDLHSHHELRA+E CE+AFN+KKDEVCVNPYHYQRVETPVLPPVL
Sbjct 121 RKGLPHVIYCRLWRWPDLHSHHELRAIETCEYAFNLKKDEVCVNPYHYQRVETPVLPPVL 180
Query 140 VPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNH 198
VPRHTEI E PPLDDY++SIPENTNFP GIEP +N IPETPPPGY+SEDGE SD QMN
Sbjct 181 VPRHTEILTELPPLDDYTNSIPENTNFPTGIEPPNNYIPETPPPGYISEDGEASDQQMNQ 240
Query 199 SMDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTV 257
SMD GSP LSP+ +SP ++ +DLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS+TV
Sbjct 241 SMDTGSPAELSPSTLSPVNHGMDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTV 300
Query 258 DGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 317
DGFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS
Sbjct 301 DGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 360
Query 318 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 377
PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV
Sbjct 361 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 420
Query 378 KGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
KGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct 421 KGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 468
>sp|P97454|SMAD5_MOUSE Mothers against decapentaplegic homolog
5 OS=Mus musculus OX=10090 GN=Smad5 PE=1 SV=2
Length=465
Score = 546 bits (1406), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 284/468 (61%), Positives = 337/468 (72%), Gaps = 49/468 (10%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
M+S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA+++
Sbjct 4 MASLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG 60
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ E
Sbjct 61 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE 120
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIEPQ 173
VC+NPYHY+RVE+PVLPPVLVPRH E + +F L +P+N FP
Sbjct 121 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP 180
Query 174 SNIP-----------------------------------ETPPPGYLSEDGETSDHQMNH 198
+N P +TPPP Y+ D + + +
Sbjct 181 NNAPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMAPDN-SQ 239
Query 199 SMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
MD S N+ P M P+ ++ D+QPV Y EP WCSI YYELN RVGE FHAS S+ VD
Sbjct 240 PMDTSS-NMIPQTM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVD 297
Query 259 GFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 317
GFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS
Sbjct 298 GFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQS 357
Query 318 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 377
NCN +G+HP TVCKIP C+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMSFV
Sbjct 358 RNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFV 417
Query 378 KGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
KGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 418 KGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465
>sp|Q56I99|SMAD5_CHICK Mothers against decapentaplegic homolog
5 OS=Gallus gallus OX=9031 GN=SMAD5 PE=1 SV=1
Length=465
Score = 545 bits (1405), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 284/468 (61%), Positives = 336/468 (72%), Gaps = 49/468 (10%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
M+S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA+++
Sbjct 4 MASLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG 60
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ E
Sbjct 61 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE 120
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIEPQ 173
VC+NPYHY+RVE+PVLPPVLVPRH+E + +F L +P N FP +
Sbjct 121 VCINPYHYKRVESPVLPPVLVPRHSEFNPQHSLLVQFRNLSHNEPHMPHNATFPDSFQQP 180
Query 174 SNIP-----------------------------------ETPPPGYLSEDGETSDHQMNH 198
++ P +TPPP Y+ D + +
Sbjct 181 NSTPFSISPNSPYPPSPASSTYPSSPASSGPSSPFQLPADTPPPAYMPPDDQMGQDN-SQ 239
Query 199 SMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
SMD S + P M P + D+QPV Y EP WCSI YYELN RVGE FHAS S+ VD
Sbjct 240 SMDT-SNTMIPQIM-PNISTRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVD 297
Query 259 GFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 317
GFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS
Sbjct 298 GFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQS 357
Query 318 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 377
NCN +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMSFV
Sbjct 358 RNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFV 417
Query 378 KGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
KGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 418 KGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465
>sp|Q5R6H7|SMAD5_PONAB Mothers against decapentaplegic homolog
5 OS=Pongo abelii OX=9601 GN=SMAD5 PE=2 SV=1
Length=465
Score = 544 bits (1402), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 284/468 (61%), Positives = 336/468 (72%), Gaps = 49/468 (10%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
M+S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA+++
Sbjct 4 MASLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG 60
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ E
Sbjct 61 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE 120
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIEPQ 173
VC+NPYHY+RVE+PVLPPVLVPRH E + +F L +P+N FP
Sbjct 121 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP 180
Query 174 SNIP-----------------------------------ETPPPGYLSEDGETSDHQMNH 198
+N P +TPPP Y+ D + +
Sbjct 181 NNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDN-SQ 239
Query 199 SMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
MD S N+ P M P+ ++ D+QPV Y EP WCSI YYELN RVGE FHAS S+ VD
Sbjct 240 PMDT-SNNMIPQIM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVD 297
Query 259 GFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 317
GFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS
Sbjct 298 GFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQS 357
Query 318 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 377
NCN +G+HP TVCKIP C+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMSFV
Sbjct 358 RNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFV 417
Query 378 KGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
KGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 418 KGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465
>sp|Q99717|SMAD5_HUMAN Mothers against decapentaplegic homolog
5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1
Length=465
Score = 544 bits (1402), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 284/468 (61%), Positives = 336/468 (72%), Gaps = 49/468 (10%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
M+S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA+++
Sbjct 4 MASLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG 60
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ E
Sbjct 61 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE 120
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIEPQ 173
VC+NPYHY+RVE+PVLPPVLVPRH E + +F L +P+N FP
Sbjct 121 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP 180
Query 174 SNIP-----------------------------------ETPPPGYLSEDGETSDHQMNH 198
+N P +TPPP Y+ D + +
Sbjct 181 NNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDN-SQ 239
Query 199 SMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
MD S N+ P M P+ ++ D+QPV Y EP WCSI YYELN RVGE FHAS S+ VD
Sbjct 240 PMDT-SNNMIPQIM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVD 297
Query 259 GFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 317
GFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS
Sbjct 298 GFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQS 357
Query 318 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 377
NCN +G+HP TVCKIP C+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMSFV
Sbjct 358 RNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFV 417
Query 378 KGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
KGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 418 KGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465
>sp|Q9W7E7|SMAD5_DANRE Mothers against decapentaplegic homolog
5 OS=Danio rerio OX=7955 GN=smad5 PE=2 SV=1
Length=464
Score = 542 bits (1397), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 284/470 (60%), Positives = 338/470 (72%), Gaps = 54/470 (11%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
MSS+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G +++LEKA+++
Sbjct 4 MSSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEDLEKALSSPG 60
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E+CE+ F K+ E
Sbjct 61 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLEVCEYPFGSKQKE 120
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIEPQ 173
VC+NPYHY+RVE+PVLPPVLVPRH+E + +F L +P N FP +
Sbjct 121 VCINPYHYKRVESPVLPPVLVPRHSEFNPQHSLLVQFRNLSHNEPHMPLNATFPESFQQH 180
Query 174 SN------------------------------------IP-ETPPPGYLSEDGETSDHQM 196
S +P +TPPP Y+ D E
Sbjct 181 SGGSSFPISPNSPYPPSPASSGTYPNSPASSGPSSPFQLPADTPPPAYMPPD-EQMGQDG 239
Query 197 NHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMT 256
+ SM+ GS +L+P M D+QPV Y EP+ WCSI YYELN RVGE +HAS S+
Sbjct 240 SQSMETGS-SLAPQNMPRG----DVQPVEYQEPSHWCSIVYYELNNRVGEAYHASSTSVL 294
Query 257 VDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 315
VDGFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSD++IFV
Sbjct 295 VDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDTSIFV 354
Query 316 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 375
QS NCN +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMS
Sbjct 355 QSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMS 414
Query 376 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
FVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 415 FVKGWGAEYHRQDVTSTPCWIEVHLHGPLQWLDKVLTQMGSPLNPISSVS 464
>sp|Q9R1V3|SMAD5_RAT Mothers against decapentaplegic homolog 5
OS=Rattus norvegicus OX=10116 GN=Smad5 PE=1 SV=1
Length=465
Score = 542 bits (1396), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 282/468 (60%), Positives = 336/468 (72%), Gaps = 49/468 (10%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
M+S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA+++
Sbjct 4 MASLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG 60
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ E
Sbjct 61 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE 120
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIEPQ 173
VC+NPYHY+RVE+PVLPPVLVPRH E + +F L +P+N FP
Sbjct 121 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP 180
Query 174 SNIP-----------------------------------ETPPPGYLSEDGETSDHQMNH 198
++ P +TPPP Y+ D + +
Sbjct 181 NSTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDN-SQ 239
Query 199 SMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
MD S N+ P M P+ ++ D+QPV Y EP WCSI YYELN RVGE FHAS S+ VD
Sbjct 240 PMDT-SNNMIPQIM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVD 297
Query 259 GFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 317
GFTDP+N++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS
Sbjct 298 GFTDPANNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQS 357
Query 318 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 377
NCN +G+HP TVCKIP C+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMSFV
Sbjct 358 RNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFV 417
Query 378 KGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
KGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 418 KGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465
>sp|P42003|MAD_DROME Protein mothers against dpp OS=Drosophila
melanogaster OX=7227 GN=Mad PE=1 SV=1
Length=455
Score = 539 bits (1389), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 279/456 (61%), Positives = 333/456 (73%), Gaps = 48/456 (11%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKK-TGQLDELEKAITTQN 59
+ S+ FT P VK+LLGWK+G++ EEKW EKAV SLVKKLKK G ++ELE+A++
Sbjct 17 LGSLFSFTSPAVKKLLGWKQGDE---EEKWAEKAVDSLVKKLKKRKGAIEELERALSCPG 73
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +ELC++ F+ K+ E
Sbjct 74 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLELCQYPFSAKQKE 133
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSH----SIPENTNF--------- 166
VC+NPYHY+RVE+PVLPPVLVPRH+E L ++H S+P N ++
Sbjct 134 VCINPYHYKRVESPVLPPVLVPRHSEFAPGHSMLQ-FNHVAEPSMPHNVSYSNSGFNSHS 192
Query 167 ----------PAGIEPQSNIP-----ETPPPGYL-SEDGETSDHQMNHSMDAGSPNLSPN 210
P+ + N P TPPP Y SEDG + N+ D G L
Sbjct 193 LSTSNTSVGSPSSVNSNPNSPYDSLAGTPPPAYSPSEDGNS-----NNPNDGG--QLLDA 245
Query 211 PMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSN-SERF 269
M D+ V+Y EPAFW SI+YYELN RVGE FH + S+ VDGFT+PSN S+R
Sbjct 246 QMG------DVAQVSYSEPAFWASIAYYELNCRVGEVFHCNNNSVIVDGFTNPSNNSDRC 299
Query 270 CLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPA 329
CLG LSNVNRN+ +E TRRHIG+GV LYY+ GEV+AECLSDSAIFVQS NCN +G+HP+
Sbjct 300 CLGQLSNVNRNSTIENTRRHIGKGVHLYYVTGEVYAECLSDSAIFVQSRNCNYHHGFHPS 359
Query 330 TVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTV 389
TVCKIPPGC+LKIFNNQEFA LL+QSVN GFEAVY+LT+MCTIRMSFVKGWGAEY RQ V
Sbjct 360 TVCKIPPGCSLKIFNNQEFAQLLSQSVNNGFEAVYELTKMCTIRMSFVKGWGAEYHRQDV 419
Query 390 TSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
TSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 420 TSTPCWIEIHLHGPLQWLDKVLTQMGSPHNAISSVS 455
>sp|Q15797|SMAD1_HUMAN Mothers against decapentaplegic homolog
1 OS=Homo sapiens OX=9606 GN=SMAD1 PE=1 SV=1
Length=465
Score = 536 bits (1382), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 286/471 (61%), Positives = 333/471 (71%), Gaps = 54/471 (11%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
++S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA++
Sbjct 3 VTSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG 59
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+ C+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ E
Sbjct 60 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 119
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIE-- 171
VC+NPYHY+RVE+PVLPPVLVPRH+E + A+F L +P N FP +
Sbjct 120 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQP 179
Query 172 --------PQSNIP---------------------------ETPPPGYLS-EDGETSDHQ 195
P S+ P +TPPP YL ED T D
Sbjct 180 NSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQD-- 237
Query 196 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 255
+ MD N+ P+ N D+Q V Y EP WCSI YYELN RVGE FHAS S+
Sbjct 238 GSQPMDT---NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSV 294
Query 256 TVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIF 314
VDGFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IF
Sbjct 295 LVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIF 354
Query 315 VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM 374
VQS NCN +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+MCTIRM
Sbjct 355 VQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRM 414
Query 375 SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
SFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 415 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
>sp|Q9I962|SMAD1_COTJA Mothers against decapentaplegic homolog
1 OS=Coturnix japonica OX=93934 GN=SMAD1 PE=2 SV=1
Length=465
Score = 536 bits (1381), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 281/470 (60%), Positives = 333/470 (71%), Gaps = 52/470 (11%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
++S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA++
Sbjct 3 VTSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG 59
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+ C+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ E
Sbjct 60 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 119
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIE-- 171
VC+NPYHY+RVE+PVLPPVLVPRH+E + A+F L +P N FP +
Sbjct 120 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPHNATFPDSFQQP 179
Query 172 --------PQSNIP---------------------------ETPPPGYLSEDGETSDHQM 196
P S+ P +TPPP YL + + + H
Sbjct 180 NSHPFPHSPNSSYPNSPGSSSSTYPHSPASSDPGSPFQMPADTPPPAYLPPEDQMT-HDT 238
Query 197 NHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMT 256
+ MD N+ + P + D+Q V Y EP WCSI YYELN RVGE FHAS S+
Sbjct 239 SQPMDT---NMMAPGIHPDIHRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSIL 295
Query 257 VDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 315
VDGFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFV
Sbjct 296 VDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFV 355
Query 316 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 375
QS NCN +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+MCT+RMS
Sbjct 356 QSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTLRMS 415
Query 376 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
FVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 416 FVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
>sp|Q1JQA2|SMAD1_BOVIN Mothers against decapentaplegic homolog
1 OS=Bos taurus OX=9913 GN=SMAD1 PE=2 SV=1
Length=465
Score = 536 bits (1381), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 287/475 (60%), Positives = 334/475 (70%), Gaps = 62/475 (13%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
++S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA++
Sbjct 3 VTSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG 59
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+ C+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ E
Sbjct 60 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 119
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIE-- 171
VC+NPYHY+RVE+PVLPPVLVPRH+E + A+F L +P N FP +
Sbjct 120 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQP 179
Query 172 --------PQSNIP---------------------------ETPPPGYLS-EDGETSDHQ 195
P S+ P +TPPP YL ED T D
Sbjct 180 NSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQD-- 237
Query 196 MNHSMDAGSPNLSPNPMSPAH----NNLDLQPVTYCEPAFWCSISYYELNQRVGETFHAS 251
GS + N M+P+ N D+Q V Y EP WCSI YYELN RVGE FHAS
Sbjct 238 -------GSQPMDTNMMAPSLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHAS 290
Query 252 QPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSD 310
S+ VDGFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSD
Sbjct 291 STSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSD 350
Query 311 SAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMC 370
S+IFVQS NCN +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+MC
Sbjct 351 SSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMC 410
Query 371 TIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
TIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 411 TIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
>sp|P97588|SMAD1_RAT Mothers against decapentaplegic homolog 1
OS=Rattus norvegicus OX=10116 GN=Smad1 PE=2 SV=1
Length=468
Score = 534 bits (1375), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 283/471 (60%), Positives = 331/471 (70%), Gaps = 51/471 (11%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
++S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA++
Sbjct 3 VTSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG 59
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+ C+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ E
Sbjct 60 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 119
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIE-- 171
VC+NPYHY+RVE+PVLPPVLVPRH+E + A+F L +P N FP +
Sbjct 120 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQP 179
Query 172 --------PQSNIP---------------------------ETPPPGYLS-EDGETSDHQ 195
P S+ P +TPPP YL ED D
Sbjct 180 HSHPFAQYPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMAQD-- 237
Query 196 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 255
+ MD N++ + N D+Q V Y EP WCSI YYELN RVGE FHAS S+
Sbjct 238 GSQPMDTNMTNMTAPTLPAEINRGDVQAVAYEEPKHWCSIVYYELNNRVGERFHASSTSV 297
Query 256 TVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIF 314
VDGFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IF
Sbjct 298 LVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIF 357
Query 315 VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM 374
VQS NCN +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE Y+LT+MCTIRM
Sbjct 358 VQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETEYELTKMCTIRM 417
Query 375 SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
SFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 418 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 468
>sp|Q9JIW5|SMAD9_MOUSE Mothers against decapentaplegic homolog
9 OS=Mus musculus OX=10090 GN=Smad9 PE=1 SV=2
Length=430
Score = 533 bits (1374), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 278/435 (64%), Positives = 332/435 (76%), Gaps = 21/435 (5%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
+SS+ FT P VKRLLGWK+G++ EEKW EKAV SLVKKLKK G +DELE+A++
Sbjct 7 ISSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDSLVKKLKKKKGAMDELERALSCPG 63
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ E
Sbjct 64 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 123
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYS----HS---IPENTNFPAGIEP 172
VC+NPYHY+RVETPVLPPVLVPRH+E + L + HS +P N +P +
Sbjct 124 VCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQ- 182
Query 173 QSNIPETPP-PGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
QS P P PG++ S ++ GSP+ S +P + + D +PV Y EP
Sbjct 183 QSLCPAPPSSPGHVFPQ---SPCPTSYPHSPGSPSESDSP----YQHSDFRPVCYEEPQH 235
Query 232 WCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHI 290
WCS++YYELN RVGETF AS S+ +DGFTDPSN+ RFCLGLLSNVNRN+ +E TRRHI
Sbjct 236 WCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHI 295
Query 291 GRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAA 350
G+GV LYY+GGEV+AEC+SDS+IFVQS NCN ++G+HPATVCKIP GC+LK+FNNQ FA
Sbjct 296 GKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQ 355
Query 351 LLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKV 410
LLAQSV+ GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKV
Sbjct 356 LLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKV 415
Query 411 LTQMGSPSIRCSSVS 425
LTQMGSP SSVS
Sbjct 416 LTQMGSPHNPISSVS 430
>sp|P70340|SMAD1_MOUSE Mothers against decapentaplegic homolog
1 OS=Mus musculus OX=10090 GN=Smad1 PE=1 SV=2
Length=465
Score = 533 bits (1372), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 284/471 (60%), Positives = 332/471 (70%), Gaps = 54/471 (11%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
++S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA++
Sbjct 3 VTSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG 59
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+ C+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ E
Sbjct 60 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 119
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTE------IPAEFPPLDDYSHSIPENTNFPAGIE-- 171
VC+NPYHY+RVE+PVLPPVLVPRH+E + A+F L +P N FP +
Sbjct 120 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQP 179
Query 172 --------PQSNIP---------------------------ETPPPGYLS-EDGETSDHQ 195
P S+ P +TPPP YL ED D
Sbjct 180 NSHPFPHSPNSSYPNSPGGSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMAQD-- 237
Query 196 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 255
+ MD N+ P+ + D+Q V Y EP WCSI YYELN RVGE FHAS S+
Sbjct 238 GSQPMDT---NMMAPPLPAEISRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSV 294
Query 256 TVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIF 314
VDGFTDPSN++ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IF
Sbjct 295 LVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIF 354
Query 315 VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM 374
VQS NCN +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+MCTIRM
Sbjct 355 VQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRM 414
Query 375 SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
SFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 415 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
>sp|O15198|SMAD9_HUMAN Mothers against decapentaplegic homolog
9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1
Length=467
Score = 529 bits (1363), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 281/465 (60%), Positives = 335/465 (72%), Gaps = 44/465 (9%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
+SS+ FT P VKRLLGWK+G++ EEKW EKAV SLVKKLKK G +DELE+A++
Sbjct 7 ISSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDSLVKKLKKKKGAMDELERALSCPG 63
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ E
Sbjct 64 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 123
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYS----HS---IPENTNFPAGIE- 171
VC+NPYHY+RVETPVLPPVLVPRH+E + L + HS +P N +P +
Sbjct 124 VCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQ 183
Query 172 -PQSNIPETPP---------------PGYLSEDGETSDHQMN------HSMDAGSPNLSP 209
P S +P +P PG SE H ++ H+ +A S S
Sbjct 184 PPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEA-SETQSG 242
Query 210 NPMSPAHN--------NLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFT 261
P+ + N D +PV Y EP WCS++YYELN RVGETF AS S+ +DGFT
Sbjct 243 QPVDATADRHVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFT 302
Query 262 DPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNC 320
DPSN+ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AEC+SDS+IFVQS NC
Sbjct 303 DPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNC 362
Query 321 NQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGW 380
N ++G+HPATVCKIP GC+LK+FNNQ FA LLAQSV+ GFE VY+LT+MCTIRMSFVKGW
Sbjct 363 NYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGW 422
Query 381 GAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
GAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 423 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467
>sp|Q9I8V2|SMAD1_DANRE Mothers against decapentaplegic homolog
1 OS=Danio rerio OX=7955 GN=smad1 PE=2 SV=1
Length=472
Score = 525 bits (1353), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 279/477 (58%), Positives = 330/477 (69%), Gaps = 59/477 (12%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
++S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELE+A++
Sbjct 3 VTSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELERALSCPG 59
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+ C+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+A+E CEF F K+ +
Sbjct 60 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKALECCEFPFGSKQKD 119
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFP-------PLDDYSHSIPENTNFPAGIEP 172
VC+NPYHY+RV++PVLPPVLVPR++E A+ PL +P+N FP
Sbjct 120 VCINPYHYKRVDSPVLPPVLVPRNSEFNAKLSMLPRFRNPLHQTEPPMPQNATFPDSFPQ 179
Query 173 QS------------------------------------------NIPETPPPGYLS-EDG 189
Q +PETPPP Y+ E+
Sbjct 180 QPANALPFTPNSPTNSYPSSPNSGTGSTATFPHSPSSSDPGSPFQMPETPPPAYMPPEEP 239
Query 190 ETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFH 249
T D + +PNL P+ N D+ PV Y EP WCSI YYELN RVGE F
Sbjct 240 MTQDCPQPMDTNLLAPNL---PLE-ISNRTDVHPVAYQEPKHWCSIVYYELNNRVGEAFL 295
Query 250 ASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECL 308
AS S+ VDGFTDPSN+ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECL
Sbjct 296 ASSTSVLVDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECL 355
Query 309 SDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTR 368
SDS+IFVQS NCN +G+HP TVCKIP C+LKIFNNQEFA LLAQSVN GFEAVY+LT+
Sbjct 356 SDSSIFVQSRNCNYHHGFHPTTVCKIPSRCSLKIFNNQEFAELLAQSVNHGFEAVYELTK 415
Query 369 MCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
MCTIRMSFVKGWGA+Y RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 416 MCTIRMSFVKGWGAKYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 472
>sp|O54835|SMAD9_RAT Mothers against decapentaplegic homolog 9
OS=Rattus norvegicus OX=10116 GN=Smad9 PE=1 SV=1
Length=434
Score = 513 bits (1320), Expect = 2e-180, Method: Compositional matrix adjust.
Identities = 276/440 (63%), Positives = 331/440 (75%), Gaps = 27/440 (6%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
+SS+ FT P VKRLLGWK+G++ EEKW EKAV SLVKKLKK G +DELE+A++
Sbjct 7 ISSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDSLVKKLKKKKGAMDELERALSCPG 63
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ E
Sbjct 64 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 123
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYS----HS---IPENTNFPAGIEP 172
VC+NPYHY+RVETPVLPPVLVPRH+E + L + HS +P N +P
Sbjct 124 VCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSF-- 181
Query 173 QSNIPETPP--PGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
Q ++ PP PG++ S ++ GSP+ S +P + + D +PV Y EP
Sbjct 182 QQSLGPAPPSSPGHVFPQ---SPCPTSYPQSPGSPSESDSP----YQHSDFRPVCYEEPL 234
Query 231 FWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRH 289
WCS++YYELN RVGETF AS S+ +DGFTDPSN+ RFCLGLLSNVNRN+ +E TRRH
Sbjct 235 HWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRH 294
Query 290 IGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNN---- 345
IG+GV LYY+GGEV+AEC+SDS+IFVQS NCN ++G+HPATVCKIP GC+LK+FNN
Sbjct 295 IGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFA 354
Query 346 QEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQ 405
Q A LLAQSV+ GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQ
Sbjct 355 QLLAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQ 414
Query 406 WLDKVLTQMGSPSIRCSSVS 425
WLDKVLTQMGSP SSVS
Sbjct 415 WLDKVLTQMGSPHNPISSVS 434
>sp|Q02330|SMA2_CAEEL Dwarfin sma-2 OS=Caenorhabditis elegans
OX=6239 GN=sma-2 PE=2 SV=2
Length=418
Score = 381 bits (979), Expect = 5e-129, Method: Compositional matrix adjust.
Identities = 207/425 (49%), Positives = 268/425 (63%), Gaps = 35/425 (8%)
Query 16 LGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQ--LDELEKAITTQ-NVNTKCITIPRSLD 72
L WK+G++ +E W +KA+ +L+KKL K + L+ LE A+ Q T+C+TIPRSLD
Sbjct 14 LKWKQGDE---DENWAKKAIDNLMKKLIKHNKQALENLEFALRCQGQQKTECVTIPRSLD 70
Query 73 GRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVE- 131
GRLQ+SHRK LPHVIYCR++RWPDL SHHEL+A+E C F + + ++C+NPYHY+RV
Sbjct 71 GRLQISHRKALPHVIYCRVYRWPDLQSHHELKAIEDCRFCYESGQKDICINPYHYKRVHA 130
Query 132 TPVLPPVLVPRHTEIP--------AEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPG 183
T VLPPVLVPR++E P A+F ++ +P+N N A + +N P
Sbjct 131 TGVLPPVLVPRYSEKPPQEVPPTLAKFQLMEMSGSRMPQNVNM-ANVNFTANQFHQYNPN 189
Query 184 YLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQR 243
+ E M+ S P P + P E FW ++SYYELN R
Sbjct 190 GIEE--------MDTSQKFDIPPGVPTCLVPFDK--------VWEEQFWATVSYYELNTR 233
Query 244 VGETFHASQPSMTVDGFTDPS-NSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYI--G 300
VGE S ++T+DGFTDP N + LGL SNVNRNA +E TRRHIG GV+L Y+
Sbjct 234 VGEQVKVSSTTITIDGFTDPCINGSKISLGLFSNVNRNATIENTRRHIGNGVKLTYVRSN 293
Query 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360
G +FA+C SDSAIFVQS NCN G+H TV KI C+LKIF+ + F LL +GF
Sbjct 294 GSLFAQCESDSAIFVQSSNCNYINGFHSTTVVKIANKCSLKIFDMEIFRQLLEDCSRRGF 353
Query 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420
+A + L +M IRMSFVKGWGAEY+RQ VTSTPCWIE+HL+ PL WLD+VL+ MG
Sbjct 354 DASFDLQKMTFIRMSFVKGWGAEYQRQDVTSTPCWIEIHLHAPLAWLDRVLSTMGPTPRP 413
Query 421 CSSVS 425
SS+S
Sbjct 414 ISSIS 418
>sp|P45896|SMA3_CAEEL Dwarfin sma-3 OS=Caenorhabditis elegans
OX=6239 GN=sma-3 PE=1 SV=1
Length=393
Score = 295 bits (756), Expect = 1e-95, Method: Compositional matrix adjust.
Identities = 179/422 (42%), Positives = 239/422 (57%), Gaps = 51/422 (12%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT----GQLDELEKAIT 56
M+ +L P VK+LLGWK GE EEKWCEKAV++LVKKLKK G L++LE +
Sbjct 1 MNGLLHMHGPAVKKLLGWKIGED---EEKWCEKAVEALVKKLKKKNNGCGTLEDLECVLA 57
Query 57 TQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAF--N 114
N++CITI +SLDGRLQVSH+KGLPHVIYCR+WRWPD+ S HELR+++ C + + +
Sbjct 58 NPCTNSRCITIAKSLDGRLQVSHKKGLPHVIYCRVWRWPDISSPHELRSIDTCSYPYESS 117
Query 115 MKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQS 174
K +C+NPYHYQR+ P ++ +P+ P S P +G S
Sbjct 118 SKTMYICINPYHYQRLSRP------QGLNSSMPSPQPI------SSPNTIWQSSGSSTAS 165
Query 175 NIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCS 234
P + + GE HQ +P + P W
Sbjct 166 CASSPSPSVFSEDGGEVQVHQ--------------------------RPPPFRHPKSWAQ 199
Query 235 ISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRG 293
I+Y+ELN RVGE F S+TVDG+T+PSNS R CLG L+NVNRN +E TR HIG+G
Sbjct 200 ITYFELNSRVGEVFKLVNLSITVDGYTNPSNSNTRICLGQLTNVNRNGTIENTRMHIGKG 259
Query 294 VRLYYIGGE--VFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAAL 351
++L + + SD +FVQS N N VC+IPP L +F F +
Sbjct 260 IQLDNKEDQMHIMITNNSDMPVFVQSKNTNLMMNMPLVKVCRIPPHSQLCVFEFNLFFQM 319
Query 352 LAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVL 411
L QS N + + +L++ C IR+SFVKGWG +Y RQ VTSTPCW+EL LN PL ++D+ +
Sbjct 320 LEQSCNDS-DGLNELSKHCFIRISFVKGWGEDYPRQDVTSTPCWLELRLNVPLAYIDQKM 378
Query 412 TQ 413
Q
Sbjct 379 KQ 380
>sp|P45897|SMA4_CAEEL Dwarfin sma-4 OS=Caenorhabditis elegans
OX=6239 GN=sma-4 PE=2 SV=1
Length=570
Score = 199 bits (506), Expect = 7e-57, Method: Compositional matrix adjust.
Identities = 155/442 (35%), Positives = 221/442 (50%), Gaps = 78/442 (18%)
Query 22 EQNGQEEKWCEKAVKSLVKKLK-KTGQLDELEKAITTQNVN-TKCITIPRSLDGRLQVSH 79
+Q G++ + KA++SLVKKLK K +LD L A+T+ T C+TI RSLDGRLQV+
Sbjct 159 QQGGEDSDFVRKAIESLVKKLKDKRIELDALITAVTSNGKQPTGCVTIQRSLDGRLQVAG 218
Query 80 RKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVL 139
RKG+PHV+Y R+WRWP + S +EL + C+ + + D +C+NPYHY+RV + +
Sbjct 219 RKGVPHVVYARIWRWPKV-SKNELVKLVQCQTSSD-HPDNICINPYHYERVVSNRITSAD 276
Query 140 VPRHTE-IPAEFPPLDDYSHSIPENTNFPAG-IEPQSNIPETPPPGYLSEDGETSDHQMN 197
H E P + L D AG I+ S+ P TPP D+ N
Sbjct 277 QSLHVENSPMKSEYLGD------------AGVIDSCSDWPNTPP-----------DNNFN 313
Query 198 HSMDAGSPNLSPNPMSPAHNN--LDLQPVTYCEP----AFWCSISYYELNQRVGETFHAS 251
P L ++P ++ +DL + P WCSI YYEL+ +GETF S
Sbjct 314 GGFAPDQPQL----VTPIISDIPIDLNQIYVPTPPQLLDNWCSIIYYELDTPIGETFKVS 369
Query 252 ---QPSMTVDGFTDP--SNSERFCLGLLSNVNRNAAVELTRRHIGRGVRL-YYIGGEVFA 305
+ VDG DP N R CLG LSNV+R A E R HIGRGV L + G +
Sbjct 370 ARDHGKVIVDGGMDPHGENEGRLCLGALSNVHRTEASEKARIHIGRGVELTAHADGNI-- 427
Query 306 ECLSDSAIFVQSPNCNQRYGWHPATVCK--IPPGCNLKIFNNQ-EFAALLAQSVNQG--- 359
S+ IFV+S + +G ++ P + +F+ + + +L +S +
Sbjct 428 SITSNCKIFVRSGYLDYTHGSEYSSKAHRFTPNESSFTVFDIRWAYMQMLRRSRSSNEAV 487
Query 360 ---------------------FEAVYQLTR-MCTIRMSFVKGWGAEYRRQTVTSTPCWIE 397
V ++ R CTI +SFVK WG Y+R+T+ TPCWIE
Sbjct 488 RAQAAAVAGYAPMSVMPAIMPDSGVDRMRRDFCTIAISFVKAWGDVYQRKTIKETPCWIE 547
Query 398 LHLNGPLQWLDKVL---TQMGS 416
+ L+ PLQ LD++L +Q GS
Sbjct 548 VTLHRPLQILDQLLKNSSQFGS 569
>sp|P97471|SMAD4_MOUSE Mothers against decapentaplegic homolog
4 OS=Mus musculus OX=10090 GN=Smad4 PE=1 SV=2
Length=551
Score = 174 bits (441), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 101/242 (42%), Positives = 135/242 (56%), Gaps = 42/242 (17%)
Query 214 PAHNNLDLQPVTYCEPA--FWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERF 269
P HN L QP PA +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RF
Sbjct 302 PVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPVVTVDGYVDPSGGDRF 361
Query 270 CLGLLSNVNRNAAVELTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHP 328
CLG LSNV+R A+E R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P
Sbjct 362 CLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAP 421
Query 329 A-TVCKIPPGCNLKIFNNQE-----------------------------------FAALL 352
V KI P +K+F+ ++ A +
Sbjct 422 GDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAI 481
Query 353 AQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLT 412
+ S G V L R+C +RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL
Sbjct 482 SLSAAAGI-GVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLH 540
Query 413 QM 414
M
Sbjct 541 TM 542
Score = 123 bits (309), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 66/125 (53%), Positives = 91/125 (73%), Gaps = 6/125 (5%)
Query 11 IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLD-ELEKAITTQNVN-TKCITIP 68
IV L+ ++G G+ E + ++A++SLVKKLK+ L AITT + +KC+TI
Sbjct 19 IVHSLMCHRQG---GESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQ 75
Query 69 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 128
R+LDGRLQV+ RKG PHVIY RLWRWPDLH +EL+ ++ C++AF++K D VCVNPYHY+
Sbjct 76 RTLDGRLQVAGRKGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYE 134
Query 129 RVETP 133
RV +P
Sbjct 135 RVVSP 139
>sp|Q13485|SMAD4_HUMAN Mothers against decapentaplegic homolog
4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1
Length=552
Score = 174 bits (440), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 101/242 (42%), Positives = 135/242 (56%), Gaps = 42/242 (17%)
Query 214 PAHNNLDLQPVTYCEPA--FWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERF 269
P HN L QP PA +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RF
Sbjct 303 PVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRF 362
Query 270 CLGLLSNVNRNAAVELTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHP 328
CLG LSNV+R A+E R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P
Sbjct 363 CLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAP 422
Query 329 A-TVCKIPPGCNLKIFNNQE-----------------------------------FAALL 352
V KI P +K+F+ ++ A +
Sbjct 423 GDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAI 482
Query 353 AQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLT 412
+ S G V L R+C +RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL
Sbjct 483 SLSAAAGI-GVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLH 541
Query 413 QM 414
M
Sbjct 542 TM 543
Score = 126 bits (316), Expect = 2e-30, Method: Compositional matrix adjust.
Identities = 67/140 (48%), Positives = 94/140 (67%), Gaps = 3/140 (2%)
Query 23 QNGQEEKWCEKAVKSLVKKLKKTGQLD-ELEKAITTQNVN-TKCITIPRSLDGRLQVSHR 80
Q G+ E + ++A++SLVKKLK+ L AITT + +KC+TI R+LDGRLQV+ R
Sbjct 28 QGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGR 87
Query 81 KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLV 140
KG PHVIY RLWRWPDLH +EL+ ++ C++AF++K D VCVNPYHY+RV +P + +
Sbjct 88 KGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERVVSPGIDLSGL 146
Query 141 PRHTEIPAEFPPLDDYSHSI 160
+ P+ D+Y H
Sbjct 147 TLQSNAPSSMMVKDEYVHDF 166
>sp|O70437|SMAD4_RAT Mothers against decapentaplegic homolog 4
OS=Rattus norvegicus OX=10116 GN=Smad4 PE=1 SV=1
Length=552
Score = 174 bits (440), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 101/242 (42%), Positives = 135/242 (56%), Gaps = 42/242 (17%)
Query 214 PAHNNLDLQPVTYCEPA--FWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERF 269
P HN L QP PA +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RF
Sbjct 303 PVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRF 362
Query 270 CLGLLSNVNRNAAVELTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHP 328
CLG LSNV+R A+E R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P
Sbjct 363 CLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAP 422
Query 329 A-TVCKIPPGCNLKIFNNQE-----------------------------------FAALL 352
V KI P +K+F+ ++ A +
Sbjct 423 GDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAI 482
Query 353 AQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLT 412
+ S G V L R+C +RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL
Sbjct 483 SLSAAAGI-GVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLH 541
Query 413 QM 414
M
Sbjct 542 TM 543
Score = 125 bits (315), Expect = 3e-30, Method: Compositional matrix adjust.
Identities = 71/159 (45%), Positives = 101/159 (64%), Gaps = 6/159 (4%)
Query 11 IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLD-ELEKAITTQNVN-TKCITIP 68
IV L+ ++G G+ E + ++A++SLVKKLK+ L AITT + +KC+TI
Sbjct 19 IVHSLMCHRQG---GESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQ 75
Query 69 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 128
R+LDGRLQV+ RKG PHVIY RLWRWPDLH +EL+ ++ C++AF++K D VCVNPYHY+
Sbjct 76 RTLDGRLQVAGRKGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYE 134
Query 129 RVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFP 167
RV +P + + + P D+Y H + P
Sbjct 135 RVVSPGIDLSGLTLQSNAPPSMLVKDEYVHDFEGQPSLP 173
>sp|Q9GKQ9|SMAD4_PIG Mothers against decapentaplegic homolog 4
OS=Sus scrofa OX=9823 GN=SMAD4 PE=2 SV=1
Length=552
Score = 174 bits (440), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 101/242 (42%), Positives = 135/242 (56%), Gaps = 42/242 (17%)
Query 214 PAHNNLDLQPVTYCEPA--FWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERF 269
P HN L QP PA +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RF
Sbjct 303 PVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRF 362
Query 270 CLGLLSNVNRNAAVELTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHP 328
CLG LSNV+R A+E R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P
Sbjct 363 CLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAP 422
Query 329 A-TVCKIPPGCNLKIFNNQE-----------------------------------FAALL 352
V KI P +K+F+ ++ A +
Sbjct 423 GDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAI 482
Query 353 AQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLT 412
+ S G V L R+C +RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL
Sbjct 483 SLSAAAGI-GVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLH 541
Query 413 QM 414
M
Sbjct 542 TM 543
Score = 125 bits (314), Expect = 4e-30, Method: Compositional matrix adjust.
Identities = 67/140 (48%), Positives = 94/140 (67%), Gaps = 3/140 (2%)
Query 23 QNGQEEKWCEKAVKSLVKKLKKTGQLD-ELEKAITTQNVN-TKCITIPRSLDGRLQVSHR 80
Q G+ E + ++A++SLVKKLK+ L AITT + +KC+TI R+LDGRLQV+ R
Sbjct 28 QGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGR 87
Query 81 KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLV 140
KG PHVIY RLWRWPDLH +EL+ ++ C++AF++K D VCVNPYHY+RV +P + +
Sbjct 88 KGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERVVSPGIDLSGL 146
Query 141 PRHTEIPAEFPPLDDYSHSI 160
+ P+ D+Y H
Sbjct 147 TLQSNAPSGMLVKDEYVHDF 166
>sp|Q1HE26|SMAD4_BOVIN Mothers against decapentaplegic homolog
4 OS=Bos taurus OX=9913 GN=SMAD4 PE=2 SV=1
Length=553
Score = 174 bits (440), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 101/242 (42%), Positives = 135/242 (56%), Gaps = 42/242 (17%)
Query 214 PAHNNLDLQPVTYCEPA--FWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERF 269
P HN L QP PA +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RF
Sbjct 304 PVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRF 363
Query 270 CLGLLSNVNRNAAVELTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHP 328
CLG LSNV+R A+E R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P
Sbjct 364 CLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAP 423
Query 329 A-TVCKIPPGCNLKIFNNQE-----------------------------------FAALL 352
V KI P +K+F+ ++ A +
Sbjct 424 GDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAI 483
Query 353 AQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLT 412
+ S G V L R+C +RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL
Sbjct 484 SLSAAAGI-GVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLH 542
Query 413 QM 414
M
Sbjct 543 TM 544
Score = 125 bits (313), Expect = 7e-30, Method: Compositional matrix adjust.
Identities = 67/140 (48%), Positives = 93/140 (66%), Gaps = 3/140 (2%)
Query 23 QNGQEEKWCEKAVKSLVKKLKKTGQLD-ELEKAITTQNVN-TKCITIPRSLDGRLQVSHR 80
Q G+ E + ++A++SLVKKLK+ L AITT + +KC+TI R+LDGRLQV+ R
Sbjct 28 QGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGR 87
Query 81 KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLV 140
KG PHVIY RLWRWPDLH +EL+ ++ C++AF++K D VCVNPYHY+RV +P + +
Sbjct 88 KGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERVVSPGIDLSGL 146
Query 141 PRHTEIPAEFPPLDDYSHSI 160
+ P D+Y H
Sbjct 147 TLQSNAPPSMLVKDEYVHDF 166
>sp|Q21733|DAF8_CAEEL Smad protein daf-8 OS=Caenorhabditis elegans
OX=6239 GN=daf-8 PE=1 SV=1
Length=546
Score = 166 bits (421), Expect = 6e-45, Method: Compositional matrix adjust.
Identities = 84/204 (41%), Positives = 114/204 (56%), Gaps = 4/204 (2%)
Query 224 VTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFT----DPSNSERFCLGLLSNVNR 279
V Y E W + YYE +GE +DGFT D RF LG +N NR
Sbjct 341 VEYEESPSWLKLIYYEEGTMIGEKADVEGHHCLIDGFTASRTDSETRSRFSLGWYNNPNR 400
Query 280 NAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCN 339
+ R IG+GVR Y + GEV+ E L + +FVQS N + G+ TV K+PP
Sbjct 401 SPQTAEVRGLIGKGVRFYLLAGEVYVENLCNIPVFVQSIGANMKNGFQLNTVSKLPPTGT 460
Query 340 LKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELH 399
+K+F+ + F+ L + + ++ VY L+RMCT+R+SF KGWG YRR TV +P W + H
Sbjct 461 MKVFDMRLFSKQLRTAAEKTYQDVYCLSRMCTVRVSFCKGWGEHYRRSTVLRSPVWFQAH 520
Query 400 LNGPLQWLDKVLTQMGSPSIRCSS 423
LN P+ W+D VLT MG+P CSS
Sbjct 521 LNNPMHWVDSVLTCMGAPPRICSS 544
Score = 49.7 bits (117), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 33/126 (26%), Positives = 62/126 (49%), Gaps = 9/126 (7%)
Query 30 WCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYC 89
W K + L + KK + A+ + T+C + + +L + + + V+
Sbjct 36 WALKVTRLLSRVAKKHQCFEAFYDAVIKGDPKTRCCP---AHNEKLIGNFGRAIMCVL-- 90
Query 90 RLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPV--LPPVLVPRHTEIP 147
R +R+P + +++++ C AFN VC+NPYHY+ VE P +PP++V + E+
Sbjct 91 RAFRFPVIRYESQVKSILTCRHAFNSHSRNVCLNPYHYRWVELPTCQVPPIIV--NKELD 148
Query 148 AEFPPL 153
PP+
Sbjct 149 YGEPPI 154
>sp|O43541|SMAD6_HUMAN Mothers against decapentaplegic homolog
6 OS=Homo sapiens OX=9606 GN=SMAD6 PE=1 SV=2
Length=496
Score = 144 bits (363), Expect = 6e-37, Method: Compositional matrix adjust.
Identities = 118/386 (31%), Positives = 175/386 (45%), Gaps = 69/386 (18%)
Query 28 EKWCEKAVKSLVKKLKKTGQLDELEKAITTQN-VNTKCITIPRSLDGRLQVSHRKGLPHV 86
E+ + SL+K+LK+ LD L +A+ ++ V C+ +PR+ L++ + P +
Sbjct 169 EQELKTVTYSLLKRLKER-SLDTLLEAVESRGGVPGGCVLVPRA---DLRLGGQPAPPQL 224
Query 87 IYCRLWRWPDLHSHHELRAMELC-EFAFNMKKDEVCVNPYHYQRVETPVLPP----VLVP 141
+ RL+RWPDL EL+ + C FA VC NPYH+ R+ P PP L P
Sbjct 225 LLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSP 284
Query 142 RHTEIPAEFPPLD----DYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMN 197
R E+ PLD S++ E TN ++ GE SD M
Sbjct 285 RD-----EYKPLDLSDSTLSYTETEATN-----------------SLITAPGEFSDASM- 321
Query 198 HSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTV 257
SP+ P+H WCS++Y+E RVG + ++++
Sbjct 322 ----------SPDATKPSH---------------WCSVAYWEHRTRVGRLYAVYDQAVSI 356
Query 258 DGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 317
F D FCLG L+ R+ +V TR IG G+ L V+A + IFV S
Sbjct 357 --FYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNS 414
Query 318 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 377
P + G V K+PPG ++K+F+ E + L + Y ++R+SF
Sbjct 415 PTLDA-PGGRALVVRKVPPGYSIKVFDF-ERSGLQHAPEPDAADGPYDPN---SVRISFA 469
Query 378 KGWGAEYRRQTVTSTPCWIELHLNGP 403
KGWG Y RQ +TS PCW+E+ LN P
Sbjct 470 KGWGPCYSRQFITSCPCWLEILLNNP 495
>sp|O35182|SMAD6_MOUSE Mothers against decapentaplegic homolog
6 OS=Mus musculus OX=10090 GN=Smad6 PE=1 SV=1
Length=495
Score = 144 bits (362), Expect = 6e-37, Method: Compositional matrix adjust.
Identities = 114/380 (30%), Positives = 174/380 (46%), Gaps = 63/380 (17%)
Query 28 EKWCEKAVKSLVKKLKKTGQLDELEKAITTQN-VNTKCITIPRSLDGRLQVSHRKGLPHV 86
E+ + SL+K+LK+ LD L +A+ ++ V C+ +PR+ L++ + P +
Sbjct 170 EQELKTVTYSLLKRLKER-SLDTLLEAVESRGGVPGGCVLVPRA---DLRLGGQPAPPQL 225
Query 87 IYCRLWRWPDLHSHHELRAMELC-EFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTE 145
+ RL+RWPDL EL+ + C F VC NPYH+ R+ P PP R +
Sbjct 226 LLGRLFRWPDLQHAVELKPLCGCHSFTAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSP 285
Query 146 IPAEFPPLD----DYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMD 201
P ++ PLD S++ E TN ++ GE SD M
Sbjct 286 -PDQYKPLDLSDSTLSYTETEATN-----------------SLITAPGEFSDASM----- 322
Query 202 AGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFT 261
SP+ P+H WCS++Y+E RVG + ++++ F
Sbjct 323 ------SPDATKPSH---------------WCSVAYWEHRTRVGRLYAVYDQAVSI--FY 359
Query 262 DPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCN 321
D FCLG L+ R+ +V TR IG G+ L V+A + IFV SP +
Sbjct 360 DLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLD 419
Query 322 QRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWG 381
G V K+PPG ++K+F+ + L Q +A + ++R+SF KGWG
Sbjct 420 A-PGGRALVVRKVPPGYSIKVFDFERSGLL------QHADAAHGPYDPHSVRISFAKGWG 472
Query 382 AEYRRQTVTSTPCWIELHLN 401
Y RQ +TS PCW+E+ LN
Sbjct 473 PCYSRQFITSCPCWLEILLN 492
>sp|Q9W734|SMAD6_CHICK Mothers against decapentaplegic homolog
6 OS=Gallus gallus OX=9031 GN=SMAD6 PE=2 SV=1
Length=431
Score = 131 bits (330), Expect = 6e-33, Method: Compositional matrix adjust.
Identities = 107/380 (28%), Positives = 167/380 (44%), Gaps = 60/380 (16%)
Query 28 EKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQV-SHRKGLPHV 86
E+ + +L+K+LK+ L+ + C+ + R G L++ + R+ PH+
Sbjct 103 ERELKAVTYALLKRLKERSLHSLLQAVESRGGTPGGCVLVAR---GELRLGAARRPPPHL 159
Query 87 IYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEI 146
+ +L+RWPDL EL+A+ C+ VC NPYH+ R+ P PP
Sbjct 160 LLGKLFRWPDLQHPAELKALCECQSFGAADGPTVCCNPYHFSRLCGPESPP--------- 210
Query 147 PAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPN 206
PP YS P + P D S + SPN
Sbjct 211 ----PP---YSRLSPNDEQKPL-------------------DLSDSTLSYTETEATNSPN 244
Query 207 LSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNS 266
++P S A + D + + WC+++Y+E RVG + + S+++ F D
Sbjct 245 VTPGEFSDASTSPDA-----VKRSHWCNVAYWEHRTRVGRLYTVYEQSVSI--FYDLPQG 297
Query 267 ERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS-----PNCN 321
FCLG L+ NR+ V TR IG G+ L V+A S+ IFV S PNC
Sbjct 298 NGFCLGQLNLENRSETVRRTRSKIGYGILLSKEPDGVWAYNRSEHPIFVNSPTLDIPNCR 357
Query 322 QRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWG 381
V K+ PG ++K+F+ ++ L + + Y ++R+SF KGWG
Sbjct 358 T------LIVRKVMPGYSIKVFDYEKSCLLQHTAELDYADGPYDPN---SVRISFAKGWG 408
Query 382 AEYRRQTVTSTPCWIELHLN 401
Y RQ +TS PCW+E+ L+
Sbjct 409 PCYSRQFITSCPCWLEILLS 428
>sp|O88406|SMAD7_RAT Mothers against decapentaplegic homolog 7
OS=Rattus norvegicus OX=10116 GN=Smad7 PE=2 SV=2
Length=426
Score = 115 bits (287), Expect = 5e-27, Method: Compositional matrix adjust.
Identities = 106/377 (28%), Positives = 174/377 (46%), Gaps = 62/377 (16%)
Query 37 SLVKKLKKTGQLDELEKAITTQN-VNTKCITIPRSLDGRL-----------QVSHRKGLP 84
S++KKLK+ QL+ L +A+ ++ T C+ +P LD RL Q LP
Sbjct 98 SVLKKLKER-QLELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPASAQPAQPPSSYSLP 156
Query 85 HVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHT 144
++ C+++RWPDL E++ + CE + + VC NP+H R L +
Sbjct 157 -LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSR---------LCELES 206
Query 145 EIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGS 204
P D+ ++P ++ P+ P +SD G+
Sbjct 207 PPPPYSRYPMDF-------------LKPTADCPDAVP---------SSDET------GGT 238
Query 205 PNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPS 264
L+P +S + L L+P + + WC ++Y+E RVG + +PS+ D F D
Sbjct 239 NYLAPGGLS--DSQLLLEPG---DRSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLP 291
Query 265 NSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRY 324
FCLG L++ N++ V+ R IG G++L V+ S IF++S +
Sbjct 292 QGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPD 351
Query 325 GWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEY 384
V K+ PG ++K F+ ++ +L Q N E + Q T+++SFVKGWG Y
Sbjct 352 S-RTLLVHKVFPGFSIKAFDYEKAYSL--QRPND-HEFMQQPWTGFTVQISFVKGWGQCY 407
Query 385 RRQTVTSTPCWIELHLN 401
RQ ++S PCW+E+ N
Sbjct 408 TRQFISSCPCWLEVIFN 424
>sp|O15105|SMAD7_HUMAN Mothers against decapentaplegic homolog
7 OS=Homo sapiens OX=9606 GN=SMAD7 PE=1 SV=1
Length=426
Score = 115 bits (287), Expect = 5e-27, Method: Compositional matrix adjust.
Identities = 106/377 (28%), Positives = 173/377 (46%), Gaps = 62/377 (16%)
Query 37 SLVKKLKKTGQLDELEKAITTQN-VNTKCITIPRSLDGRLQVSHRKG-----------LP 84
S++KKLK+ QL+ L +A+ ++ T C+ +P LD RL G LP
Sbjct 98 SVLKKLKER-QLELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLP 156
Query 85 HVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHT 144
++ C+++RWPDL E++ + CE + + VC NP+H R L +
Sbjct 157 -LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSR---------LCELES 206
Query 145 EIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGS 204
P D+ ++P ++ P+ P ET G+
Sbjct 207 PPPPYSRYPMDF-------------LKPTADCPDAVP-----SSAET----------GGT 238
Query 205 PNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPS 264
L+P +S + L L+P + + WC ++Y+E RVG + +PS+ D F D
Sbjct 239 NYLAPGGLS--DSQLLLEPG---DRSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLP 291
Query 265 NSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRY 324
FCLG L++ N++ V+ R IG G++L V+ S IF++S +
Sbjct 292 QGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPD 351
Query 325 GWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEY 384
V K+ PG ++K F+ ++ +L Q N E + Q T+++SFVKGWG Y
Sbjct 352 S-RTLLVHKVFPGFSIKAFDYEKAYSL--QRPND-HEFMQQPWTGFTVQISFVKGWGQCY 407
Query 385 RRQTVTSTPCWIELHLN 401
RQ ++S PCW+E+ N
Sbjct 408 TRQFISSCPCWLEVIFN 424
>sp|O35253|SMAD7_MOUSE Mothers against decapentaplegic homolog
7 OS=Mus musculus OX=10090 GN=Smad7 PE=1 SV=1
Length=426
Score = 114 bits (285), Expect = 1e-26, Method: Compositional matrix adjust.
Identities = 106/377 (28%), Positives = 172/377 (46%), Gaps = 62/377 (16%)
Query 37 SLVKKLKKTGQLDELEKAITTQN-VNTKCITIPRSLDGRL-----------QVSHRKGLP 84
S++KKLK+ QL+ L +A+ ++ T C+ +P LD RL Q LP
Sbjct 98 SVLKKLKER-QLELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPASAQPAQPPSSYSLP 156
Query 85 HVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHT 144
++ C+++RWPDL E++ + CE + + VC NP+H R L +
Sbjct 157 -LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSR---------LCELES 206
Query 145 EIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGS 204
P D+ ++P + P+ P ET G+
Sbjct 207 PPPPYSRYPMDF-------------LKPTAGCPDAVP-----SSAET----------GGT 238
Query 205 PNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPS 264
L+P +S + L L+P + + WC ++Y+E RVG + +PS+ D F D
Sbjct 239 NYLAPGGLS--DSQLLLEPG---DRSHWCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLP 291
Query 265 NSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRY 324
FCLG L++ N++ V+ R IG G++L V+ S IF++S +
Sbjct 292 QGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPD 351
Query 325 GWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEY 384
V K+ PG ++K F+ ++ +L Q N E + Q T+++SFVKGWG Y
Sbjct 352 S-RTLLVHKVFPGFSIKAFDYEKAYSL--QRPND-HEFMQQPWTGFTVQISFVKGWGQCY 407
Query 385 RRQTVTSTPCWIELHLN 401
RQ ++S PCW+E+ N
Sbjct 408 TRQFISSCPCWLEVIFN 424
>sp|F5GUE5|DAF14_CAEEL Smad-related protein daf-14 OS=Caenorhabditis
elegans OX=6239 GN=daf-14 PE=1 SV=1
Length=331
Score = 105 bits (262), Expect = 4e-24, Method: Compositional matrix adjust.
Identities = 67/199 (34%), Positives = 99/199 (50%), Gaps = 7/199 (4%)
Query 219 LDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVN 278
LD +P E WC+I YYEL R+G+ F A P++T+DG T S+ R L + +
Sbjct 121 LDPEPKYPKEEKPWCTIFYYELTVRLGKAFEAKVPTITIDGATGASDECRMSLTSQPS-S 179
Query 279 RNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGC 338
RN+ R +G G++L Y GE++ L+D +FVQ P NQ V ++
Sbjct 180 RNSKSSQIRNTVGAGIQLAYENGELWLTVLTDQIVFVQCPFLNQTLNKPLKYVFRLQNKG 239
Query 339 N---LKIFNNQEFAALLAQSVNQGFEAVYQLTRM---CTIRMSFVKGWGAEYRRQTVTST 392
+ +KIF+ ++F ++ E RM IR+SF KG+G Y R V +
Sbjct 240 DQKRMKIFDKEQFEQEKTLALGPLTEKEVADERMRIFSNIRVSFCKGFGETYSRLKVVNL 299
Query 393 PCWIELHLNGPLQWLDKVL 411
PCWIE+ L+ P D V
Sbjct 300 PCWIEIILHEPADEYDTVF 318
>sp|Q95QI7|DAF3_CAEEL Smad protein daf-3 OS=Caenorhabditis elegans
OX=6239 GN=daf-3 PE=1 SV=1
Length=892
Score = 100 bits (249), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 78/219 (36%), Positives = 111/219 (51%), Gaps = 25/219 (11%)
Query 23 QNGQEEKWCEKAVKSLVKKLKKTGQLDE--LEKAITTQNVNTKCITIPRSLDGRLQVSHR 80
+N + ++ +KA +SLVKKLK + ++ ++ T CITIPR+LDGRLQV R
Sbjct 233 KNNIDREFDQKACESLVKKLKDKKNDLQNLIDVVLSKGTKYTGCITIPRTLDGRLQVHGR 292
Query 81 KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV---------- 130
KG PHV+Y +LWR+ ++ + +E R ++ C+ AF MK D VCVNPYHY+ V
Sbjct 293 KGFPHVVYGKLWRFNEM-TKNETRHVDHCKHAFEMKSDMVCVNPYHYEIVIGTMIVGQRD 351
Query 131 -ETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEP---QSNIPETPPPGYLS 186
+ +PP HT P P+DD S IP PA I P + P P L
Sbjct 352 HDNRDMPPPHQRYHT--PGRQDPVDDMSRFIP-----PASIRPPPMNMHTRPQPMPQQLP 404
Query 187 EDGETSDHQMNHSMDAGSPNLSPNPMSP-AHNNLDLQPV 224
G T H + H P ++P H L++ P+
Sbjct 405 SVGATFAHPLPHQAPHNPGVSHPYSIAPQTHYPLNMNPI 443
Score = 59.7 bits (143), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 56/213 (26%), Positives = 87/213 (41%), Gaps = 37/213 (17%)
Query 232 WCSISYYELNQRVGETFHASQPSMTVDG-FTDPSNSERFCLGLLSNVNRNAAVELTRRHI 290
W +I YYE N ++GE S+ + VDG F N R+ LGL N R R+ I
Sbjct 657 WGTIVYYEKNLQIGEK-KCSRGNFHVDGGFICSEN--RYSLGLEPNPIREPVAFKVRKAI 713
Query 291 GRGVRL-YYIGGEVFAECLSDSAIFVQSPNCN-QRYGWHPATVCKIPPGCNLKIFN---- 344
G+R Y G V+ + +FV S + Q G V K+ ++K F
Sbjct 714 VDGIRFSYKKDGSVWLQNRMKYPVFVTSGYLDEQSGGLKKDKVHKVYGCASIKTFGFNVS 773
Query 345 ---------NQEFAALLAQSVNQGFEAVYQ-----------------LTRMCTIRMSFVK 378
+++ A + Q +Y+ L + C +R+SF K
Sbjct 774 KQIIRDALLSKQMATMYLQGKLTPMNYIYEKKTQEELRREATRTTDSLAKYCCVRVSFCK 833
Query 379 GWGAEY-RRQTVTSTPCWIELHLNGPLQWLDKV 410
G+G Y R ++ P WIEL +N ++D +
Sbjct 834 GFGEAYPERPSIHDCPVWIELKINIAYDFMDSI 866
>sp|F4HXP9|MYO9_ARATH Myosin-9 OS=Arabidopsis thaliana OX=3702
GN=XI-C PE=2 SV=1
Length=1538
Score = 33.5 bits (75), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 0/47 (0%)
Query 48 LDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRW 94
L LE A+ + + T I RSLD + V+ R GL +Y RL+ W
Sbjct 373 LKALEDALCKRVMITPEEVIKRSLDPQSAVTSRDGLAKTVYSRLFDW 419
>sp|Q9PMD4|G6PI_CAMJE Glucose-6-phosphate isomerase OS=Campylobacter
jejuni subsp. jejuni serotype O:2 (strain ATCC 700819
/ NCTC 11168) OX=192222 GN=pgi PE=3 SV=1
Length=406
Score = 33.1 bits (74), Expect = 5.5, Method: Compositional matrix adjust.
Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 7/71 (10%)
Query 58 QNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELC-EFAFNMK 116
+N+ KC IP ++ GR + G+ + +C ++ L + C E F K
Sbjct 164 ENLGIKCFFIPANVGGRFSILSAVGIVPLCFC------GYNAKALLEGAKACFEDFFTHK 217
Query 117 KDEVCVNPYHY 127
KDE+ YHY
Sbjct 218 KDEILQKAYHY 228
>sp|A1A619|OCAD1_XENLA OCIA domain-containing protein 1 OS=Xenopus
laevis OX=8355 GN=ociad1 PE=2 SV=3
Length=252
Score = 32.3 bits (72), Expect = 6.9, Method: Compositional matrix adjust.
Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 9/110 (8%)
Query 126 HYQRVETPVLPPVLVPRHTEIPAEFPP-LDDYSHSIPENTNFPAGIEPQSNIPETPPPGY 184
++R+E L L + ++P ++P ++S P + P G SN+ E P Y
Sbjct 101 KFKRLENSPLGEALRQGYRKLPTQYPAGTSEFSDINPTTPSAPGGF--ASNMVEPPSSVY 158
Query 185 LSEDGETSDH-----QMNHSMDAG-SPNLSPNPMSPAHNNLDLQPVTYCE 228
S+ G TSD + S +G S N++P P + + +P+TY E
Sbjct 159 SSQYGSTSDSVPFSTSLGESSPSGISDNIAPEPAALIEDAPTRKPMTYDE 208
Lambda K H a alpha
0.319 0.135 0.431 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 41816195296
Results from round 2
Query= sp|P84022|SMAD3_HUMAN Mothers against decapentaplegic homolog 3
OS=Homo sapiens OX=9606 GN=SMAD3 PE=1 SV=1
Length=425
Score E
Sequences producing significant alignments: (Bits) Value
Sequences used in model and found again:
sp|P84025|SMAD3_RAT Mothers against decapentaplegic homolog 3 OS=... 662 0.0
sp|P84024|SMAD3_PIG Mothers against decapentaplegic homolog 3 OS=... 662 0.0
sp|Q8BUN5|SMAD3_MOUSE Mothers against decapentaplegic homolog 3 O... 662 0.0
sp|P84022|SMAD3_HUMAN Mothers against decapentaplegic homolog 3 O... 662 0.0
sp|P84023|SMAD3_CHICK Mothers against decapentaplegic homolog 3 O... 654 0.0
sp|Q62432|SMAD2_MOUSE Mothers against decapentaplegic homolog 2 O... 619 0.0
sp|O70436|SMAD2_RAT Mothers against decapentaplegic homolog 2 OS=... 618 0.0
sp|Q15796|SMAD2_HUMAN Mothers against decapentaplegic homolog 2 O... 618 0.0
sp|Q5R7C0|SMAD2_PONAB Mothers against decapentaplegic homolog 2 O... 617 0.0
sp|Q1W668|SMAD2_BOVIN Mothers against decapentaplegic homolog 2 O... 616 0.0
sp|Q56I99|SMAD5_CHICK Mothers against decapentaplegic homolog 5 O... 598 0.0
sp|Q9I9P9|SMAD2_DANRE Mothers against decapentaplegic homolog 2 O... 597 0.0
sp|Q9W7E7|SMAD5_DANRE Mothers against decapentaplegic homolog 5 O... 591 0.0
sp|Q5R6H7|SMAD5_PONAB Mothers against decapentaplegic homolog 5 O... 589 0.0
sp|Q99717|SMAD5_HUMAN Mothers against decapentaplegic homolog 5 O... 589 0.0
sp|P97454|SMAD5_MOUSE Mothers against decapentaplegic homolog 5 O... 589 0.0
sp|P42003|MAD_DROME Protein mothers against dpp OS=Drosophila mel... 587 0.0
sp|Q9R1V3|SMAD5_RAT Mothers against decapentaplegic homolog 5 OS=... 587 0.0
sp|P97588|SMAD1_RAT Mothers against decapentaplegic homolog 1 OS=... 586 0.0
sp|Q9JIW5|SMAD9_MOUSE Mothers against decapentaplegic homolog 9 O... 585 0.0
sp|Q9I962|SMAD1_COTJA Mothers against decapentaplegic homolog 1 O... 582 0.0
sp|P70340|SMAD1_MOUSE Mothers against decapentaplegic homolog 1 O... 580 0.0
sp|Q1JQA2|SMAD1_BOVIN Mothers against decapentaplegic homolog 1 O... 580 0.0
sp|Q15797|SMAD1_HUMAN Mothers against decapentaplegic homolog 1 O... 580 0.0
sp|Q9I8V2|SMAD1_DANRE Mothers against decapentaplegic homolog 1 O... 577 0.0
sp|O15198|SMAD9_HUMAN Mothers against decapentaplegic homolog 9 O... 576 0.0
sp|O54835|SMAD9_RAT Mothers against decapentaplegic homolog 9 OS=... 564 0.0
sp|Q02330|SMA2_CAEEL Dwarfin sma-2 OS=Caenorhabditis elegans OX=6... 507 2e-178
sp|P45896|SMA3_CAEEL Dwarfin sma-3 OS=Caenorhabditis elegans OX=6... 428 1e-147
sp|Q9W734|SMAD6_CHICK Mothers against decapentaplegic homolog 6 O... 376 7e-127
sp|O43541|SMAD6_HUMAN Mothers against decapentaplegic homolog 6 O... 369 4e-123
sp|P45897|SMA4_CAEEL Dwarfin sma-4 OS=Caenorhabditis elegans OX=6... 365 1e-120
sp|O35182|SMAD6_MOUSE Mothers against decapentaplegic homolog 6 O... 362 1e-120
sp|O15105|SMAD7_HUMAN Mothers against decapentaplegic homolog 7 O... 334 2e-110
sp|O88406|SMAD7_RAT Mothers against decapentaplegic homolog 7 OS=... 329 1e-108
sp|O35253|SMAD7_MOUSE Mothers against decapentaplegic homolog 7 O... 329 2e-108
sp|P97471|SMAD4_MOUSE Mothers against decapentaplegic homolog 4 O... 323 2e-104
sp|O70437|SMAD4_RAT Mothers against decapentaplegic homolog 4 OS=... 322 4e-104
sp|Q21733|DAF8_CAEEL Smad protein daf-8 OS=Caenorhabditis elegans... 277 7e-87
sp|Q1HE26|SMAD4_BOVIN Mothers against decapentaplegic homolog 4 O... 251 1e-76
sp|Q9GKQ9|SMAD4_PIG Mothers against decapentaplegic homolog 4 OS=... 251 2e-76
sp|Q13485|SMAD4_HUMAN Mothers against decapentaplegic homolog 4 O... 248 9e-76
sp|F5GUE5|DAF14_CAEEL Smad-related protein daf-14 OS=Caenorhabdit... 240 7e-75
sp|Q95QI7|DAF3_CAEEL Smad protein daf-3 OS=Caenorhabditis elegans... 186 2e-50
Sequences not found previously or not previously below threshold:
sp|Q9JKS6|PCLO_RAT Protein piccolo OS=Rattus norvegicus OX=10116 ... 44.0 0.003
sp|Q92985|IRF7_HUMAN Interferon regulatory factor 7 OS=Homo sapie... 41.3 0.014
sp|A8AUS1|SSPB_STRGC Streptococcal surface protein B OS=Streptoco... 41.7 0.015
sp|Q9UJ55|MAGL2_HUMAN MAGE-like protein 2 OS=Homo sapiens OX=9606... 41.3 0.017
sp|A8AUS0|SSPA_STRGC Streptococcal surface protein A OS=Streptoco... 40.9 0.024
sp|P16952|SSPB_STRGN Agglutinin receptor OS=Streptococcus gordoni... 40.5 0.031
sp|Q06852|SLAP1_ACET2 Cell surface glycoprotein 1 OS=Acetivibrio ... 40.2 0.040
sp|Q9HCD6|TANC2_HUMAN Protein TANC2 OS=Homo sapiens OX=9606 GN=TA... 39.4 0.075
sp|P25623|SYP1_YEAST Suppressor of yeast profilin deletion OS=Sac... 39.4 0.079
sp|G5EEL0|LIDB1_CAEEL LIM domain-binding protein 1 OS=Caenorhabdi... 39.0 0.091
sp|Q9Y6V0|PCLO_HUMAN Protein piccolo OS=Homo sapiens OX=9606 GN=P... 38.6 0.12
sp|A2A690|TANC2_MOUSE Protein TANC2 OS=Mus musculus OX=10090 GN=T... 38.6 0.13
sp|Q63155|DCC_RAT Netrin receptor DCC OS=Rattus norvegicus OX=101... 38.6 0.14
sp|P70211|DCC_MOUSE Netrin receptor DCC OS=Mus musculus OX=10090 ... 38.6 0.14
sp|Q9SZ15|LIP5_ARATH Protein HOMOLOG OF MAMMALIAN LYST-INTERACTIN... 37.8 0.19
sp|Q8BI84|TGO1_MOUSE Transport and Golgi organization protein 1 h... 37.8 0.25
sp|A1DLN3|SEC16_NEOFI COPII coat assembly protein sec16 OS=Neosar... 37.5 0.26
sp|P9WHW5|PSTP_MYCTU Serine/threonine protein phosphatase PstP OS... 37.5 0.27
sp|Q3UR85|MYRF_MOUSE Myelin regulatory factor OS=Mus musculus OX=... 37.5 0.30
sp|O81765|PLRX4_ARATH Pollen-specific leucine-rich repeat extensi... 37.1 0.32
sp|A1CZE5|INO80_NEOFI Chromatin-remodeling ATPase INO80 OS=Neosar... 37.1 0.35
sp|P46593|HWP1_CANAL Hyphal wall protein 1 OS=Candida albicans (s... 37.1 0.37
sp|Q8N6P7|I22R1_HUMAN Interleukin-22 receptor subunit alpha-1 OS=... 36.7 0.40
sp|Q6PDK2|KMT2D_MOUSE Histone-lysine N-methyltransferase 2D OS=Mu... 37.1 0.46
sp|C4YHA6|HWP1_CANAW Hyphal wall protein 1 OS=Candida albicans (s... 36.7 0.47
sp|Q2UCB7|MCA1B_ASPOR Metacaspase-1B OS=Aspergillus oryzae (strai... 36.3 0.50
sp|Q9FZ35|PRP1_ARATH Proline-rich protein 1 OS=Arabidopsis thalia... 36.3 0.52
sp|I1S4N7|BECN1_GIBZE Vacuolar protein sorting-associated protein... 36.3 0.53
sp|Q9CXK9|RBM33_MOUSE RNA-binding protein 33 OS=Mus musculus OX=1... 36.7 0.54
sp|P43146|DCC_HUMAN Netrin receptor DCC OS=Homo sapiens OX=9606 G... 36.7 0.55
sp|Q8L611|SC31B_ARATH Protein transport protein SEC31 homolog B O... 36.7 0.56
sp|P0CAQ1|UBP16_EMENI Ubiquitin carboxyl-terminal hydrolase 16 OS... 36.3 0.61
sp|A2R4T4|SEC16_ASPNC COPII coat assembly protein sec16 OS=Asperg... 36.3 0.63
sp|Q61329|ZFHX3_MOUSE Zinc finger homeobox protein 3 OS=Mus muscu... 36.3 0.71
sp|P29674|LHX1_XENLA LIM/homeobox protein Lhx1 OS=Xenopus laevis ... 35.5 0.83
sp|Q67724|RDRP_HASV Methyltransferase/helicase/RNA-directed RNA p... 35.9 0.92
sp|Q16U49|MED14_AEDAE Mediator of RNA polymerase II transcription... 35.9 0.97
sp|Q96EV2|RBM33_HUMAN RNA-binding protein 33 OS=Homo sapiens OX=9... 35.5 1.2
sp|Q7RTP6|MICA3_HUMAN [F-actin]-monooxygenase MICAL3 OS=Homo sapi... 35.5 1.2
sp|Q640P2|ANGL1_MOUSE Angiopoietin-related protein 1 OS=Mus muscu... 35.1 1.3
sp|Q9HCU0|CD248_HUMAN Endosialin OS=Homo sapiens OX=9606 GN=CD248... 35.1 1.3
sp|P9WHW4|PSTP_MYCTO Serine/threonine protein phosphatase PstP OS... 35.1 1.3
sp|Q6AXT8|SF3A2_RAT Splicing factor 3A subunit 2 OS=Rattus norveg... 35.1 1.3
sp|Q1HVG4|EBNA4_EBVA8 Epstein-Barr nuclear antigen 4 OS=Epstein-B... 35.1 1.4
sp|Q32L53|LFG1_BOVIN Protein lifeguard 1 OS=Bos taurus OX=9913 GN... 34.8 1.4
sp|Q91924|SNAI2_XENLA Zinc finger protein SNAI2 OS=Xenopus laevis... 34.4 1.5
sp|Q7SAN9|BRO1_NEUCR Vacuolar protein-sorting protein bro-1 OS=Ne... 34.8 1.8
sp|Q64289|NDF1_RAT Neurogenic differentiation factor 1 OS=Rattus ... 34.4 1.8
sp|Q60867|NDF1_MOUSE Neurogenic differentiation factor 1 OS=Mus m... 34.4 1.8
sp|Q5XJ13|ANKS6_DANRE Ankyrin repeat and SAM domain-containing pr... 34.8 1.8
sp|Q9LYW5|LUL1_ARATH Probable E3 ubiquitin-protein ligase LUL1 OS... 34.4 1.9
sp|Q62203|SF3A2_MOUSE Splicing factor 3A subunit 2 OS=Mus musculu... 34.8 1.9
sp|Q96NZ1|FOXN4_HUMAN Forkhead box protein N4 OS=Homo sapiens OX=... 34.4 2.2
sp|P53236|RSC1_YEAST Chromatin structure-remodeling complex subun... 34.4 2.3
sp|O60130|YH7G_SCHPO Putative transcriptional regulatory protein ... 34.4 2.4
sp|Q9NQW1|SC31B_HUMAN Protein transport protein Sec31B OS=Homo sa... 34.4 2.4
sp|Q9CXC9|ETV5_MOUSE ETS translocation variant 5 OS=Mus musculus ... 34.0 2.9
sp|Q5PT56|NTCP4_RAT Sodium/bile acid cotransporter 4 OS=Rattus no... 33.6 3.3
sp|O42854|YFHH_SCHPO SH3 domain-containing protein C23A1.17 OS=Sc... 34.0 3.7
sp|Q921L5|COG2_MOUSE Conserved oligomeric Golgi complex subunit 2... 33.6 3.8
sp|P83093|STIM2_MOUSE Stromal interaction molecule 2 OS=Mus muscu... 33.6 3.9
sp|O13637|SEC31_SCHPO Protein transport protein sec31 OS=Schizosa... 33.6 4.1
sp|Q59YH3|CG11_CANAL G1/S-specific cyclin CCN1 OS=Candida albican... 33.2 5.6
sp|P0CY18|CG11_CANAX G1/S-specific cyclin CLN1 OS=Candida albican... 33.2 5.6
sp|C4YR54|CG11_CANAW G1/S-specific cyclin CCN1 OS=Candida albican... 33.2 5.6
sp|Q5UNX8|YR722_MIMIV Uncharacterized protein R722 OS=Acanthamoeb... 33.2 5.9
sp|P31257|HXC10_MOUSE Homeobox protein Hox-C10 OS=Mus musculus OX... 32.8 6.1
sp|O14686|KMT2D_HUMAN Histone-lysine N-methyltransferase 2D OS=Ho... 33.2 6.3
sp|Q7ZXH3|TAB3_XENLA Mitogen-activated protein kinase kinase kina... 32.8 6.6
sp|J9VT33|CUF1_CRYNH Copper-dependent transcription factor 1 OS=C... 32.8 6.7
sp|Q3UHH1|ZSWM8_MOUSE Zinc finger SWIM domain-containing protein ... 33.2 6.9
sp|Q6J1Y9|UBP19_RAT Ubiquitin carboxyl-terminal hydrolase 19 OS=R... 32.8 7.2
sp|Q9NYD6|HXC10_HUMAN Homeobox protein Hox-C10 OS=Homo sapiens OX... 32.4 7.3
sp|A2T7H7|HXC10_PONPY Homeobox protein Hox-C10 OS=Pongo pygmaeus ... 32.4 7.4
sp|Q8BT14|CNOT4_MOUSE CCR4-NOT transcription complex subunit 4 OS... 32.4 8.0
sp|Q6BXI1|SEC16_DEBHA COPII coat assembly protein SEC16 OS=Debary... 32.8 8.5
sp|Q9UIF9|BAZ2A_HUMAN Bromodomain adjacent to zinc finger domain ... 32.8 8.8
sp|A7MKW3|ZIPA_CROS8 Cell division protein ZipA OS=Cronobacter sa... 32.1 8.8
sp|Q3UH66|WNK2_MOUSE Serine/threonine-protein kinase WNK2 OS=Mus ... 32.8 8.9
sp|J9VND4|PBP1_CRYNH PAB1-binding protein 1 OS=Cryptococcus neofo... 32.4 9.0
sp|Q01443|SSP2_PLAYO Sporozoite surface protein 2 OS=Plasmodium y... 32.4 9.2
sp|Q7Z429|LFG1_HUMAN Protein lifeguard 1 OS=Homo sapiens OX=9606 ... 32.1 9.9
>sp|P84025|SMAD3_RAT Mothers against decapentaplegic homolog 3
OS=Rattus norvegicus OX=10116 GN=Smad3 PE=1 SV=1
Length=425
Score = 662 bits (1708), Expect = 0.0, Method: Composition-based stats.
Identities = 425/425 (100%), Positives = 425/425 (100%), Gaps = 0/425 (0%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60
MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV
Sbjct 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60
Query 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120
NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV
Sbjct 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120
Query 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP 180
CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP
Sbjct 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP 180
Query 181 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 240
PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL
Sbjct 181 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 240
Query 241 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 300
NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG
Sbjct 241 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 300
Query 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360
GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF
Sbjct 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360
Query 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420
EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR
Sbjct 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420
Query 421 CSSVS 425
CSSVS
Sbjct 421 CSSVS 425
>sp|P84024|SMAD3_PIG Mothers against decapentaplegic homolog 3
OS=Sus scrofa OX=9823 GN=SMAD3 PE=2 SV=1
Length=425
Score = 662 bits (1708), Expect = 0.0, Method: Composition-based stats.
Identities = 425/425 (100%), Positives = 425/425 (100%), Gaps = 0/425 (0%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60
MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV
Sbjct 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60
Query 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120
NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV
Sbjct 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120
Query 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP 180
CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP
Sbjct 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP 180
Query 181 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 240
PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL
Sbjct 181 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 240
Query 241 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 300
NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG
Sbjct 241 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 300
Query 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360
GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF
Sbjct 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360
Query 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420
EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR
Sbjct 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420
Query 421 CSSVS 425
CSSVS
Sbjct 421 CSSVS 425
>sp|Q8BUN5|SMAD3_MOUSE Mothers against decapentaplegic homolog
3 OS=Mus musculus OX=10090 GN=Smad3 PE=1 SV=2
Length=425
Score = 662 bits (1708), Expect = 0.0, Method: Composition-based stats.
Identities = 425/425 (100%), Positives = 425/425 (100%), Gaps = 0/425 (0%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60
MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV
Sbjct 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60
Query 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120
NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV
Sbjct 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120
Query 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP 180
CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP
Sbjct 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP 180
Query 181 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 240
PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL
Sbjct 181 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 240
Query 241 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 300
NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG
Sbjct 241 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 300
Query 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360
GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF
Sbjct 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360
Query 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420
EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR
Sbjct 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420
Query 421 CSSVS 425
CSSVS
Sbjct 421 CSSVS 425
>sp|P84022|SMAD3_HUMAN Mothers against decapentaplegic homolog
3 OS=Homo sapiens OX=9606 GN=SMAD3 PE=1 SV=1
Length=425
Score = 662 bits (1708), Expect = 0.0, Method: Composition-based stats.
Identities = 425/425 (100%), Positives = 425/425 (100%), Gaps = 0/425 (0%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60
MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV
Sbjct 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60
Query 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120
NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV
Sbjct 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120
Query 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP 180
CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP
Sbjct 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP 180
Query 181 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 240
PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL
Sbjct 181 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 240
Query 241 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 300
NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG
Sbjct 241 NQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG 300
Query 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360
GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF
Sbjct 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360
Query 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420
EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR
Sbjct 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420
Query 421 CSSVS 425
CSSVS
Sbjct 421 CSSVS 425
>sp|P84023|SMAD3_CHICK Mothers against decapentaplegic homolog
3 OS=Gallus gallus OX=9031 GN=SMAD3 PE=2 SV=1
Length=426
Score = 654 bits (1688), Expect = 0.0, Method: Composition-based stats.
Identities = 421/426 (99%), Positives = 424/426 (99%), Gaps = 1/426 (0%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNV 60
MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQN+
Sbjct 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNI 60
Query 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEV 120
NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAME+CE+AFNMKKDEV
Sbjct 61 NTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMEMCEYAFNMKKDEV 120
Query 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPET 179
CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN IPET
Sbjct 121 CVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNYIPET 180
Query 180 PPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYE 239
PPPGYLSEDGETSDHQMN SMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYE
Sbjct 181 PPPGYLSEDGETSDHQMNPSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYE 240
Query 240 LNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYI 299
LNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYI
Sbjct 241 LNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYI 300
Query 300 GGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQG 359
GGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQG
Sbjct 301 GGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQG 360
Query 360 FEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSI 419
FEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSI
Sbjct 361 FEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSI 420
Query 420 RCSSVS 425
RCSSVS
Sbjct 421 RCSSVS 426
>sp|Q62432|SMAD2_MOUSE Mothers against decapentaplegic homolog
2 OS=Mus musculus OX=10090 GN=Smad2 PE=1 SV=2
Length=467
Score = 619 bits (1597), Expect = 0.0, Method: Composition-based stats.
Identities = 391/467 (84%), Positives = 410/467 (88%), Gaps = 42/467 (9%)
Query 1 MSSILPFTPPIVKRLLGWKKG----------EQNGQEEKWCEKAVKSLVKKLKKTGQLDE 50
MSSILPFTPP+VKRLLGWKK EQNGQEEKWCEKAVKSLVKKLKKTG+LDE
Sbjct 1 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60
Query 51 LEKAITTQNVNTKCITIP------------------------------RSLDGRLQVSHR 80
LEKAITTQN NTKC+TIP RSLDGRLQVSHR
Sbjct 61 LEKAITTQNCNTKCVTIPSTCSEIWGLSTANTVDQWDTTGLYSFSEQTRSLDGRLQVSHR 120
Query 81 KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLV 140
KGLPHVIYCRLWRWPDLHSHHEL+A+E CE+AFN+KKDEVCVNPYHYQRVETPVLPPVLV
Sbjct 121 KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV 180
Query 141 PRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHS 199
PRHTEI E PPLDDY+HSIPENTNFPAGIEPQSN IPETPPPGY+SEDGETSD Q+N S
Sbjct 181 PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQS 240
Query 200 MDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
MD GSP LSP +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS+TVD
Sbjct 241 MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVD 300
Query 259 GFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 318
GFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP
Sbjct 301 GFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 360
Query 319 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 378
NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK
Sbjct 361 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 420
Query 379 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct 421 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467
>sp|O70436|SMAD2_RAT Mothers against decapentaplegic homolog 2
OS=Rattus norvegicus OX=10116 GN=Smad2 PE=1 SV=1
Length=467
Score = 618 bits (1594), Expect = 0.0, Method: Composition-based stats.
Identities = 390/467 (84%), Positives = 410/467 (88%), Gaps = 42/467 (9%)
Query 1 MSSILPFTPPIVKRLLGWKKG----------EQNGQEEKWCEKAVKSLVKKLKKTGQLDE 50
MSSILPFTPP+VKRLLGWKK EQNGQEEKWCEKAVKSLVKKLKKTG+LDE
Sbjct 1 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60
Query 51 LEKAITTQNVNTKCITIP------------------------------RSLDGRLQVSHR 80
LEKAITTQN NTKC+TIP RSLDGRLQVSHR
Sbjct 61 LEKAITTQNCNTKCVTIPSTCSEIWGLSTANTVDQWDTTGLYSFSEQTRSLDGRLQVSHR 120
Query 81 KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLV 140
KGLPHVIYCRLWRWPDLHSHHEL+A+E CE+AF++KKDEVCVNPYHYQRVETPVLPPVLV
Sbjct 121 KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFSLKKDEVCVNPYHYQRVETPVLPPVLV 180
Query 141 PRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHS 199
PRHTEI E PPLDDY+HSIPENTNFPAGIEPQSN IPETPPPGY+SEDGETSD Q+N S
Sbjct 181 PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQS 240
Query 200 MDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
MD GSP LSP +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS+TVD
Sbjct 241 MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVD 300
Query 259 GFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 318
GFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP
Sbjct 301 GFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 360
Query 319 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 378
NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK
Sbjct 361 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 420
Query 379 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct 421 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467
>sp|Q15796|SMAD2_HUMAN Mothers against decapentaplegic homolog
2 OS=Homo sapiens OX=9606 GN=SMAD2 PE=1 SV=1
Length=467
Score = 618 bits (1593), Expect = 0.0, Method: Composition-based stats.
Identities = 391/467 (84%), Positives = 410/467 (88%), Gaps = 42/467 (9%)
Query 1 MSSILPFTPPIVKRLLGWKKG----------EQNGQEEKWCEKAVKSLVKKLKKTGQLDE 50
MSSILPFTPP+VKRLLGWKK EQNGQEEKWCEKAVKSLVKKLKKTG+LDE
Sbjct 1 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60
Query 51 LEKAITTQNVNTKCITIP------------------------------RSLDGRLQVSHR 80
LEKAITTQN NTKC+TIP RSLDGRLQVSHR
Sbjct 61 LEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHR 120
Query 81 KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLV 140
KGLPHVIYCRLWRWPDLHSHHEL+A+E CE+AFN+KKDEVCVNPYHYQRVETPVLPPVLV
Sbjct 121 KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV 180
Query 141 PRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHS 199
PRHTEI E PPLDDY+HSIPENTNFPAGIEPQSN IPETPPPGY+SEDGETSD Q+N S
Sbjct 181 PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQS 240
Query 200 MDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
MD GSP LSP +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS+TVD
Sbjct 241 MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVD 300
Query 259 GFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 318
GFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP
Sbjct 301 GFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 360
Query 319 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 378
NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK
Sbjct 361 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 420
Query 379 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct 421 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467
>sp|Q5R7C0|SMAD2_PONAB Mothers against decapentaplegic homolog
2 OS=Pongo abelii OX=9601 GN=SMAD2 PE=2 SV=1
Length=467
Score = 617 bits (1591), Expect = 0.0, Method: Composition-based stats.
Identities = 390/467 (84%), Positives = 410/467 (88%), Gaps = 42/467 (9%)
Query 1 MSSILPFTPPIVKRLLGWKKG----------EQNGQEEKWCEKAVKSLVKKLKKTGQLDE 50
MSSILPFTPP+VKRLLGWKK EQNGQEEKWCEKAVKSLVKKLKKTG+LDE
Sbjct 1 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60
Query 51 LEKAITTQNVNTKCITIP------------------------------RSLDGRLQVSHR 80
LEKAITTQN NTKC+TIP RSLDGRLQVSHR
Sbjct 61 LEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHR 120
Query 81 KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLV 140
KGLPHVIYCRLWRWPDLHSHHEL+A+E CE+AFN+K+DEVCVNPYHYQRVETPVLPPVLV
Sbjct 121 KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKEDEVCVNPYHYQRVETPVLPPVLV 180
Query 141 PRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHS 199
PRHTEI E PPLDDY+HSIPENTNFPAGIEPQSN IPETPPPGY+SEDGETSD Q+N S
Sbjct 181 PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQS 240
Query 200 MDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
MD GSP LSP +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS+TVD
Sbjct 241 MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVD 300
Query 259 GFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 318
GFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP
Sbjct 301 GFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 360
Query 319 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 378
NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK
Sbjct 361 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 420
Query 379 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct 421 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467
>sp|Q1W668|SMAD2_BOVIN Mothers against decapentaplegic homolog
2 OS=Bos taurus OX=9913 GN=SMAD2 PE=2 SV=1
Length=467
Score = 616 bits (1589), Expect = 0.0, Method: Composition-based stats.
Identities = 390/467 (84%), Positives = 409/467 (88%), Gaps = 42/467 (9%)
Query 1 MSSILPFTPPIVKRLLGWKKG----------EQNGQEEKWCEKAVKSLVKKLKKTGQLDE 50
MSSILPFTPP+VKRLLGWKK EQNGQEEKWCEKAVKSLVKKLKKTG+LDE
Sbjct 1 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE 60
Query 51 LEKAITTQNVNTKCITIP------------------------------RSLDGRLQVSHR 80
LEKAITTQN NTKC+TIP RSLDGRLQVSHR
Sbjct 61 LEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHR 120
Query 81 KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLV 140
KGLPHVIYCRLWRWPDLHSHHEL+A+E CE+AFN+KKDEVCVNPYHYQRVETPVLPPVLV
Sbjct 121 KGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLV 180
Query 141 PRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNHS 199
PRHTEI E PPLDDY+HSIPENTNFPAGIEPQSN IPETPPPGY+SEDGETSD Q+N S
Sbjct 181 PRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQS 240
Query 200 MDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
MD GSP LSP +SP +++LDLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS+TVD
Sbjct 241 MDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVD 300
Query 259 GFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 318
GFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP
Sbjct 301 GFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSP 360
Query 319 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 378
NCNQRYGWHPATVCKIPPGCNLKIFNNQ FAALLAQSVNQGFEAVYQLTRMCTIRMSFVK
Sbjct 361 NCNQRYGWHPATVCKIPPGCNLKIFNNQGFAALLAQSVNQGFEAVYQLTRMCTIRMSFVK 420
Query 379 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct 421 GWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 467
>sp|Q56I99|SMAD5_CHICK Mothers against decapentaplegic homolog
5 OS=Gallus gallus OX=9031 GN=SMAD5 PE=1 SV=1
Length=465
Score = 598 bits (1541), Expect = 0.0, Method: Composition-based stats.
Identities = 280/468 (60%), Positives = 332/468 (71%), Gaps = 49/468 (10%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
M+S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA+++
Sbjct 4 MASLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG 60
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ E
Sbjct 61 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE 120
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAE------FPPLDDYSHSIPENTNFPAGIEPQ 173
VC+NPYHY+RVE+PVLPPVLVPRH+E + F L +P N FP +
Sbjct 121 VCINPYHYKRVESPVLPPVLVPRHSEFNPQHSLLVQFRNLSHNEPHMPHNATFPDSFQQP 180
Query 174 SNIP-----------------------------------ETPPPGYLSEDGETSDHQMNH 198
++ P +TPPP Y+ D + ++
Sbjct 181 NSTPFSISPNSPYPPSPASSTYPSSPASSGPSSPFQLPADTPPPAYMPPDDQMGQ---DN 237
Query 199 SMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
S + N + P + D+QPV Y EP WCSI YYELN RVGE FHAS S+ VD
Sbjct 238 SQSMDTSNTMIPQIMPNISTRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVD 297
Query 259 GFTDPSNS-ERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 317
GFTDPSN+ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS
Sbjct 298 GFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQS 357
Query 318 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 377
NCN +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMSFV
Sbjct 358 RNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFV 417
Query 378 KGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
KGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 418 KGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465
>sp|Q9I9P9|SMAD2_DANRE Mothers against decapentaplegic homolog
2 OS=Danio rerio OX=7955 GN=smad2 PE=2 SV=1
Length=468
Score = 597 bits (1540), Expect = 0.0, Method: Composition-based stats.
Identities = 381/468 (81%), Positives = 400/468 (85%), Gaps = 43/468 (9%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEE-----------KWCEKAVKSLVKKLKKTGQLD 49
MSSILPFTPP+VKRLLGWKK KWCEKAVKSLVKKLKKTGQLD
Sbjct 1 MSSILPFTPPVVKRLLGWKKSASGSSGAGGGGEQNGQEEKWCEKAVKSLVKKLKKTGQLD 60
Query 50 ELEKAITTQNVNTKCITIP------------------------------RSLDGRLQVSH 79
ELEKAITTQN NTKC+TIP RSLDGRLQVSH
Sbjct 61 ELEKAITTQNRNTKCVTIPSNCSEIWGLSTPNTIEQWDTSGLYSYPDQTRSLDGRLQVSH 120
Query 80 RKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVL 139
RKGLPHVIYCRLWRWPDLHSHHELRA+E CE+AFN+KKDEVCVNPYHYQRVETPVLPPVL
Sbjct 121 RKGLPHVIYCRLWRWPDLHSHHELRAIETCEYAFNLKKDEVCVNPYHYQRVETPVLPPVL 180
Query 140 VPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLSEDGETSDHQMNH 198
VPRHTEI E PPLDDY++SIPENTNFP GIEP +N IPETPPPGY+SEDGE SD QMN
Sbjct 181 VPRHTEILTELPPLDDYTNSIPENTNFPTGIEPPNNYIPETPPPGYISEDGEASDQQMNQ 240
Query 199 SMDAGSP-NLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTV 257
SMD GSP LSP+ +SP ++ +DLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS+TV
Sbjct 241 SMDTGSPAELSPSTLSPVNHGMDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTV 300
Query 258 DGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 317
DGFTDPSNSERFCLGLLSNVNRNA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS
Sbjct 301 DGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 360
Query 318 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 377
PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV
Sbjct 361 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 420
Query 378 KGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
KGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPS+RCSS+S
Sbjct 421 KGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 468
>sp|Q9W7E7|SMAD5_DANRE Mothers against decapentaplegic homolog
5 OS=Danio rerio OX=7955 GN=smad5 PE=2 SV=1
Length=464
Score = 591 bits (1524), Expect = 0.0, Method: Composition-based stats.
Identities = 283/470 (60%), Positives = 334/470 (71%), Gaps = 54/470 (11%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
MSS+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G +++LEKA+++
Sbjct 4 MSSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEDLEKALSSPG 60
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E+CE+ F K+ E
Sbjct 61 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLEVCEYPFGSKQKE 120
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPA------EFPPLDDYSHSIPENTNFPAGIEPQ 173
VC+NPYHY+RVE+PVLPPVLVPRH+E +F L +P N FP +
Sbjct 121 VCINPYHYKRVESPVLPPVLVPRHSEFNPQHSLLVQFRNLSHNEPHMPLNATFPESFQQH 180
Query 174 SNIP-------------------------------------ETPPPGYLSEDGETSDHQM 196
S +TPPP Y+ D E
Sbjct 181 SGGSSFPISPNSPYPPSPASSGTYPNSPASSGPSSPFQLPADTPPPAYMPPD-EQMGQDG 239
Query 197 NHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMT 256
+ SM+ GS +L+P M D+QPV Y EP+ WCSI YYELN RVGE +HAS S+
Sbjct 240 SQSMETGS-SLAPQNMP----RGDVQPVEYQEPSHWCSIVYYELNNRVGEAYHASSTSVL 294
Query 257 VDGFTDPSNS-ERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 315
VDGFTDPSN+ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSD++IFV
Sbjct 295 VDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDTSIFV 354
Query 316 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 375
QS NCN +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMS
Sbjct 355 QSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMS 414
Query 376 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
FVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 415 FVKGWGAEYHRQDVTSTPCWIEVHLHGPLQWLDKVLTQMGSPLNPISSVS 464
>sp|Q5R6H7|SMAD5_PONAB Mothers against decapentaplegic homolog
5 OS=Pongo abelii OX=9601 GN=SMAD5 PE=2 SV=1
Length=465
Score = 589 bits (1518), Expect = 0.0, Method: Composition-based stats.
Identities = 284/468 (61%), Positives = 334/468 (71%), Gaps = 49/468 (10%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
M+S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA+++
Sbjct 4 MASLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG 60
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ E
Sbjct 61 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE 120
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAE------FPPLDDYSHSIPENTNFPAGIEPQ 173
VC+NPYHY+RVE+PVLPPVLVPRH E + F L +P+N FP
Sbjct 121 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP 180
Query 174 SNIP-----------------------------------ETPPPGYLSEDGETSDHQMNH 198
+N P +TPPP Y+ D + +
Sbjct 181 NNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDN-SQ 239
Query 199 SMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
MD S N+ P M P+ ++ D+QPV Y EP WCSI YYELN RVGE FHAS S+ VD
Sbjct 240 PMDT-SNNMIPQIM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVD 297
Query 259 GFTDPSNS-ERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 317
GFTDPSN+ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS
Sbjct 298 GFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQS 357
Query 318 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 377
NCN +G+HP TVCKIP C+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMSFV
Sbjct 358 RNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFV 417
Query 378 KGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
KGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 418 KGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465
>sp|Q99717|SMAD5_HUMAN Mothers against decapentaplegic homolog
5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1
Length=465
Score = 589 bits (1518), Expect = 0.0, Method: Composition-based stats.
Identities = 284/468 (61%), Positives = 334/468 (71%), Gaps = 49/468 (10%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
M+S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA+++
Sbjct 4 MASLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG 60
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ E
Sbjct 61 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE 120
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAE------FPPLDDYSHSIPENTNFPAGIEPQ 173
VC+NPYHY+RVE+PVLPPVLVPRH E + F L +P+N FP
Sbjct 121 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP 180
Query 174 SNIP-----------------------------------ETPPPGYLSEDGETSDHQMNH 198
+N P +TPPP Y+ D + +
Sbjct 181 NNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDN-SQ 239
Query 199 SMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
MD S N+ P M P+ ++ D+QPV Y EP WCSI YYELN RVGE FHAS S+ VD
Sbjct 240 PMDT-SNNMIPQIM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVD 297
Query 259 GFTDPSNS-ERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 317
GFTDPSN+ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS
Sbjct 298 GFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQS 357
Query 318 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 377
NCN +G+HP TVCKIP C+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMSFV
Sbjct 358 RNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFV 417
Query 378 KGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
KGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 418 KGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465
>sp|P97454|SMAD5_MOUSE Mothers against decapentaplegic homolog
5 OS=Mus musculus OX=10090 GN=Smad5 PE=1 SV=2
Length=465
Score = 589 bits (1517), Expect = 0.0, Method: Composition-based stats.
Identities = 284/468 (61%), Positives = 335/468 (72%), Gaps = 49/468 (10%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
M+S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA+++
Sbjct 4 MASLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG 60
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ E
Sbjct 61 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE 120
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAE------FPPLDDYSHSIPENTNFPAGIEPQ 173
VC+NPYHY+RVE+PVLPPVLVPRH E + F L +P+N FP
Sbjct 121 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP 180
Query 174 SNIP-----------------------------------ETPPPGYLSEDGETSDHQMNH 198
+N P +TPPP Y+ D + + +
Sbjct 181 NNAPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMAPDN-SQ 239
Query 199 SMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
MD S N+ P M P+ ++ D+QPV Y EP WCSI YYELN RVGE FHAS S+ VD
Sbjct 240 PMDTSS-NMIPQTM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVD 297
Query 259 GFTDPSNS-ERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 317
GFTDPSN+ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS
Sbjct 298 GFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQS 357
Query 318 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 377
NCN +G+HP TVCKIP C+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMSFV
Sbjct 358 RNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFV 417
Query 378 KGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
KGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 418 KGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465
>sp|P42003|MAD_DROME Protein mothers against dpp OS=Drosophila
melanogaster OX=7227 GN=Mad PE=1 SV=1
Length=455
Score = 587 bits (1513), Expect = 0.0, Method: Composition-based stats.
Identities = 268/442 (61%), Positives = 322/442 (73%), Gaps = 20/442 (5%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
+ S+ FT P VK+LLGWK+G++ EEKW EKAV SLVKKLKK G ++ELE+A++
Sbjct 17 LGSLFSFTSPAVKKLLGWKQGDE---EEKWAEKAVDSLVKKLKKRKGAIEELERALSCPG 73
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +ELC++ F+ K+ E
Sbjct 74 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLELCQYPFSAKQKE 133
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDY---SHSIPENTNFP-AGIEPQSN 175
VC+NPYHY+RVE+PVLPPVLVPRH+E L S+P N ++ +G S
Sbjct 134 VCINPYHYKRVESPVLPPVLVPRHSEFAPGHSMLQFNHVAEPSMPHNVSYSNSGFNSHSL 193
Query 176 IPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNN-----------LDLQPV 224
G S + + P SP+ ++N D+ V
Sbjct 194 STSNTSVGSPSSVNSNPNSPYDSLAGTPPPAYSPSEDGNSNNPNDGGQLLDAQMGDVAQV 253
Query 225 TYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAV 283
+Y EPAFW SI+YYELN RVGE FH + S+ VDGFT+PSN+ R CLG LSNVNRN+ +
Sbjct 254 SYSEPAFWASIAYYELNCRVGEVFHCNNNSVIVDGFTNPSNNSDRCCLGQLSNVNRNSTI 313
Query 284 ELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF 343
E TRRHIG+GV LYY+ GEV+AECLSDSAIFVQS NCN +G+HP+TVCKIPPGC+LKIF
Sbjct 314 ENTRRHIGKGVHLYYVTGEVYAECLSDSAIFVQSRNCNYHHGFHPSTVCKIPPGCSLKIF 373
Query 344 NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 403
NNQEFA LL+QSVN GFEAVY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GP
Sbjct 374 NNQEFAQLLSQSVNNGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGP 433
Query 404 LQWLDKVLTQMGSPSIRCSSVS 425
LQWLDKVLTQMGSP SSVS
Sbjct 434 LQWLDKVLTQMGSPHNAISSVS 455
>sp|Q9R1V3|SMAD5_RAT Mothers against decapentaplegic homolog 5
OS=Rattus norvegicus OX=10116 GN=Smad5 PE=1 SV=1
Length=465
Score = 587 bits (1512), Expect = 0.0, Method: Composition-based stats.
Identities = 282/468 (60%), Positives = 334/468 (71%), Gaps = 49/468 (10%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
M+S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA+++
Sbjct 4 MASLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG 60
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ E
Sbjct 61 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE 120
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAE------FPPLDDYSHSIPENTNFPAGIEPQ 173
VC+NPYHY+RVE+PVLPPVLVPRH E + F L +P+N FP
Sbjct 121 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP 180
Query 174 SNIP-----------------------------------ETPPPGYLSEDGETSDHQMNH 198
++ P +TPPP Y+ D + +
Sbjct 181 NSTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDN-SQ 239
Query 199 SMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVD 258
MD S N+ P M P+ ++ D+QPV Y EP WCSI YYELN RVGE FHAS S+ VD
Sbjct 240 PMDT-SNNMIPQIM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVD 297
Query 259 GFTDPSNS-ERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS 317
GFTDP+N+ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS
Sbjct 298 GFTDPANNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQS 357
Query 318 PNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFV 377
NCN +G+HP TVCKIP C+LKIFNNQEFA LLAQSVN GFEAVY+LT+MCTIRMSFV
Sbjct 358 RNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFV 417
Query 378 KGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
KGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 418 KGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465
>sp|P97588|SMAD1_RAT Mothers against decapentaplegic homolog 1
OS=Rattus norvegicus OX=10116 GN=Smad1 PE=2 SV=1
Length=468
Score = 586 bits (1510), Expect = 0.0, Method: Composition-based stats.
Identities = 279/470 (59%), Positives = 327/470 (70%), Gaps = 49/470 (10%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
++S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA++
Sbjct 3 VTSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG 59
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+ C+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ E
Sbjct 60 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 119
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAE------FPPLDDYSHSIPENTNFPAGIE-- 171
VC+NPYHY+RVE+PVLPPVLVPRH+E + F L +P N FP +
Sbjct 120 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQP 179
Query 172 --------PQSNIP---------------------------ETPPPGYLSEDGETSDHQM 196
P S+ P +TPPP YL + +
Sbjct 180 HSHPFAQYPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPE-DPMAQDG 238
Query 197 NHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMT 256
+ MD N++ + N D+Q V Y EP WCSI YYELN RVGE FHAS S+
Sbjct 239 SQPMDTNMTNMTAPTLPAEINRGDVQAVAYEEPKHWCSIVYYELNNRVGERFHASSTSVL 298
Query 257 VDGFTDPSNS-ERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 315
VDGFTDPSN+ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFV
Sbjct 299 VDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFV 358
Query 316 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 375
QS NCN +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE Y+LT+MCTIRMS
Sbjct 359 QSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETEYELTKMCTIRMS 418
Query 376 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
FVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 419 FVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 468
>sp|Q9JIW5|SMAD9_MOUSE Mothers against decapentaplegic homolog
9 OS=Mus musculus OX=10090 GN=Smad9 PE=1 SV=2
Length=430
Score = 585 bits (1509), Expect = 0.0, Method: Composition-based stats.
Identities = 272/434 (63%), Positives = 326/434 (75%), Gaps = 19/434 (4%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
+SS+ FT P VKRLLGWK+G++ EEKW EKAV SLVKKLKK G +DELE+A++
Sbjct 7 ISSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDSLVKKLKKKKGAMDELERALSCPG 63
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ E
Sbjct 64 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 123
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDY-------SHSIPENTNFPAGIEP 172
VC+NPYHY+RVETPVLPPVLVPRH+E + L + +P N +P +
Sbjct 124 VCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQ 183
Query 173 QSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFW 232
PG++ S ++ GSP+ S +P + + D +PV Y EP W
Sbjct 184 SLCPAPPSSPGHVFPQ---SPCPTSYPHSPGSPSESDSP----YQHSDFRPVCYEEPQHW 236
Query 233 CSISYYELNQRVGETFHASQPSMTVDGFTDPSNS-ERFCLGLLSNVNRNAAVELTRRHIG 291
CS++YYELN RVGETF AS S+ +DGFTDPSN+ RFCLGLLSNVNRN+ +E TRRHIG
Sbjct 237 CSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIG 296
Query 292 RGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAAL 351
+GV LYY+GGEV+AEC+SDS+IFVQS NCN ++G+HPATVCKIP GC+LK+FNNQ FA L
Sbjct 297 KGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQL 356
Query 352 LAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVL 411
LAQSV+ GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVL
Sbjct 357 LAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVL 416
Query 412 TQMGSPSIRCSSVS 425
TQMGSP SSVS
Sbjct 417 TQMGSPHNPISSVS 430
>sp|Q9I962|SMAD1_COTJA Mothers against decapentaplegic homolog
1 OS=Coturnix japonica OX=93934 GN=SMAD1 PE=2 SV=1
Length=465
Score = 582 bits (1499), Expect = 0.0, Method: Composition-based stats.
Identities = 278/470 (59%), Positives = 328/470 (70%), Gaps = 52/470 (11%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
++S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA++
Sbjct 3 VTSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG 59
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+ C+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ E
Sbjct 60 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 119
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPA------EFPPLDDYSHSIPENTNFPAGIEPQ 173
VC+NPYHY+RVE+PVLPPVLVPRH+E +F L +P N FP +
Sbjct 120 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPHNATFPDSFQQP 179
Query 174 SNIP-------------------------------------ETPPPGYLSEDGETSDHQM 196
++ P +TPPP YL + + H
Sbjct 180 NSHPFPHSPNSSYPNSPGSSSSTYPHSPASSDPGSPFQMPADTPPPAYLPPEDQM-THDT 238
Query 197 NHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMT 256
+ MD N+ + P + D+Q V Y EP WCSI YYELN RVGE FHAS S+
Sbjct 239 SQPMDT---NMMAPGIHPDIHRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSIL 295
Query 257 VDGFTDPSNS-ERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 315
VDGFTDPSN+ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFV
Sbjct 296 VDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFV 355
Query 316 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 375
QS NCN +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+MCT+RMS
Sbjct 356 QSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTLRMS 415
Query 376 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
FVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 416 FVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
>sp|P70340|SMAD1_MOUSE Mothers against decapentaplegic homolog
1 OS=Mus musculus OX=10090 GN=Smad1 PE=1 SV=2
Length=465
Score = 580 bits (1496), Expect = 0.0, Method: Composition-based stats.
Identities = 278/470 (59%), Positives = 327/470 (70%), Gaps = 52/470 (11%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
++S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA++
Sbjct 3 VTSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG 59
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+ C+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ E
Sbjct 60 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 119
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPA------EFPPLDDYSHSIPENTNFPAGIEPQ 173
VC+NPYHY+RVE+PVLPPVLVPRH+E +F L +P N FP +
Sbjct 120 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQP 179
Query 174 SNIP-------------------------------------ETPPPGYLSEDGETSDHQM 196
++ P +TPPP YL + +
Sbjct 180 NSHPFPHSPNSSYPNSPGGSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPE-DPMAQDG 238
Query 197 NHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMT 256
+ MD N+ P+ + D+Q V Y EP WCSI YYELN RVGE FHAS S+
Sbjct 239 SQPMDT---NMMAPPLPAEISRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVL 295
Query 257 VDGFTDPSNS-ERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFV 315
VDGFTDPSN+ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFV
Sbjct 296 VDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFV 355
Query 316 QSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMS 375
QS NCN +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+MCTIRMS
Sbjct 356 QSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMS 415
Query 376 FVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
FVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 416 FVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
>sp|Q1JQA2|SMAD1_BOVIN Mothers against decapentaplegic homolog
1 OS=Bos taurus OX=9913 GN=SMAD1 PE=2 SV=1
Length=465
Score = 580 bits (1496), Expect = 0.0, Method: Composition-based stats.
Identities = 280/466 (60%), Positives = 325/466 (70%), Gaps = 44/466 (9%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
++S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA++
Sbjct 3 VTSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG 59
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+ C+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ E
Sbjct 60 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 119
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPA------EFPPLDDYSHSIPENTNFPAGIEPQ 173
VC+NPYHY+RVE+PVLPPVLVPRH+E +F L +P N FP +
Sbjct 120 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQP 179
Query 174 SN--IPETPPPGYLSEDGETSDH--QMNHSMDAGSPNLSPNPMSP--------------- 214
++ P +P Y + G +S S D GSP P P
Sbjct 180 NSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGS 239
Query 215 --------------AHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGF 260
N D+Q V Y EP WCSI YYELN RVGE FHAS S+ VDGF
Sbjct 240 QPMDTNMMAPSLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGF 299
Query 261 TDPSNS-ERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPN 319
TDPSN+ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IFVQS N
Sbjct 300 TDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRN 359
Query 320 CNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKG 379
CN +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+MCTIRMSFVKG
Sbjct 360 CNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKG 419
Query 380 WGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
WGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 420 WGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
>sp|Q15797|SMAD1_HUMAN Mothers against decapentaplegic homolog
1 OS=Homo sapiens OX=9606 GN=SMAD1 PE=1 SV=1
Length=465
Score = 580 bits (1494), Expect = 0.0, Method: Composition-based stats.
Identities = 281/471 (60%), Positives = 326/471 (69%), Gaps = 54/471 (11%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
++S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA++
Sbjct 3 VTSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG 59
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+ C+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ E
Sbjct 60 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 119
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPA------EFPPLDDYSHSIPENTNFPAGIEPQ 173
VC+NPYHY+RVE+PVLPPVLVPRH+E +F L +P N FP +
Sbjct 120 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQP 179
Query 174 SNIP-------------------------------------ETPPPGYL-SEDGETSDHQ 195
++ P +TPPP YL ED T D
Sbjct 180 NSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGS 239
Query 196 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM 255
N+ P+ N D+Q V Y EP WCSI YYELN RVGE FHAS S+
Sbjct 240 QPMDT-----NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSV 294
Query 256 TVDGFTDPSNS-ERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIF 314
VDGFTDPSN+ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECLSDS+IF
Sbjct 295 LVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIF 354
Query 315 VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM 374
VQS NCN +G+HP TVCKIP GC+LKIFNNQEFA LLAQSVN GFE VY+LT+MCTIRM
Sbjct 355 VQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRM 414
Query 375 SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
SFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 415 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
>sp|Q9I8V2|SMAD1_DANRE Mothers against decapentaplegic homolog
1 OS=Danio rerio OX=7955 GN=smad1 PE=2 SV=1
Length=472
Score = 577 bits (1486), Expect = 0.0, Method: Composition-based stats.
Identities = 278/477 (58%), Positives = 328/477 (69%), Gaps = 59/477 (12%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
++S+ FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELE+A++
Sbjct 3 VTSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELERALSCPG 59
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+ C+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+A+E CEF F K+ +
Sbjct 60 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKALECCEFPFGSKQKD 119
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFP-------PLDDYSHSIPENTNFPAGIEP 172
VC+NPYHY+RV++PVLPPVLVPR++E A+ PL +P+N FP
Sbjct 120 VCINPYHYKRVDSPVLPPVLVPRNSEFNAKLSMLPRFRNPLHQTEPPMPQNATFPDSFPQ 179
Query 173 QS------------------------------------------NIPETPPPGYLS-EDG 189
Q +PETPPP Y+ E+
Sbjct 180 QPANALPFTPNSPTNSYPSSPNSGTGSTATFPHSPSSSDPGSPFQMPETPPPAYMPPEEP 239
Query 190 ETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFH 249
T D + L+PN N D+ PV Y EP WCSI YYELN RVGE F
Sbjct 240 MTQDCPQPM----DTNLLAPNLPLEISNRTDVHPVAYQEPKHWCSIVYYELNNRVGEAFL 295
Query 250 ASQPSMTVDGFTDPSNS-ERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECL 308
AS S+ VDGFTDPSN+ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AECL
Sbjct 296 ASSTSVLVDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECL 355
Query 309 SDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTR 368
SDS+IFVQS NCN +G+HP TVCKIP C+LKIFNNQEFA LLAQSVN GFEAVY+LT+
Sbjct 356 SDSSIFVQSRNCNYHHGFHPTTVCKIPSRCSLKIFNNQEFAELLAQSVNHGFEAVYELTK 415
Query 369 MCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
MCTIRMSFVKGWGA+Y RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 416 MCTIRMSFVKGWGAKYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 472
>sp|O15198|SMAD9_HUMAN Mothers against decapentaplegic homolog
9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1
Length=467
Score = 576 bits (1485), Expect = 0.0, Method: Composition-based stats.
Identities = 273/464 (59%), Positives = 325/464 (70%), Gaps = 42/464 (9%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
+SS+ FT P VKRLLGWK+G++ EEKW EKAV SLVKKLKK G +DELE+A++
Sbjct 7 ISSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDSLVKKLKKKKGAMDELERALSCPG 63
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ E
Sbjct 64 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 123
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDY-------SHSIPENTNFPAGIE- 171
VC+NPYHY+RVETPVLPPVLVPRH+E + L + +P N +P +
Sbjct 124 VCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQ 183
Query 172 -PQSNIPETPPPGYLSED-GETSDHQMNHSMDAGSPNLSPNPMSP--------------- 214
P S +P +P + + H + SP P
Sbjct 184 PPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQSGQ 243
Query 215 ------------AHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTD 262
+ N D +PV Y EP WCS++YYELN RVGETF AS S+ +DGFTD
Sbjct 244 PVDATADRHVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTD 303
Query 263 PSNS-ERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCN 321
PSN+ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AEC+SDS+IFVQS NCN
Sbjct 304 PSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCN 363
Query 322 QRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWG 381
++G+HPATVCKIP GC+LK+FNNQ FA LLAQSV+ GFE VY+LT+MCTIRMSFVKGWG
Sbjct 364 YQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWG 423
Query 382 AEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
AEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct 424 AEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467
>sp|O54835|SMAD9_RAT Mothers against decapentaplegic homolog 9
OS=Rattus norvegicus OX=10116 GN=Smad9 PE=1 SV=1
Length=434
Score = 564 bits (1452), Expect = 0.0, Method: Composition-based stats.
Identities = 271/438 (62%), Positives = 325/438 (74%), Gaps = 23/438 (5%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
+SS+ FT P VKRLLGWK+G++ EEKW EKAV SLVKKLKK G +DELE+A++
Sbjct 7 ISSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDSLVKKLKKKKGAMDELERALSCPG 63
Query 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ E
Sbjct 64 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 123
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDY-------SHSIPENTNFPAGIEP 172
VC+NPYHY+RVETPVLPPVLVPRH+E + L + +P N +P +
Sbjct 124 VCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQ 183
Query 173 QSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFW 232
PG++ S ++ GSP+ S +P + + D +PV Y EP W
Sbjct 184 SLGPAPPSSPGHVFPQ---SPCPTSYPQSPGSPSESDSP----YQHSDFRPVCYEEPLHW 236
Query 233 CSISYYELNQRVGETFHASQPSMTVDGFTDPSNS-ERFCLGLLSNVNRNAAVELTRRHIG 291
CS++YYELN RVGETF AS S+ +DGFTDPSN+ RFCLGLLSNVNRN+ +E TRRHIG
Sbjct 237 CSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIG 296
Query 292 RGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNN----QE 347
+GV LYY+GGEV+AEC+SDS+IFVQS NCN ++G+HPATVCKIP GC+LK+FNN Q
Sbjct 297 KGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQL 356
Query 348 FAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWL 407
A LLAQSV+ GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWL
Sbjct 357 LAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWL 416
Query 408 DKVLTQMGSPSIRCSSVS 425
DKVLTQMGSP SSVS
Sbjct 417 DKVLTQMGSPHNPISSVS 434
>sp|Q02330|SMA2_CAEEL Dwarfin sma-2 OS=Caenorhabditis elegans
OX=6239 GN=sma-2 PE=2 SV=2
Length=418
Score = 507 bits (1304), Expect = 2e-178, Method: Composition-based stats.
Identities = 206/425 (48%), Positives = 266/425 (63%), Gaps = 35/425 (8%)
Query 16 LGWKKGEQNGQEEKWCEKAVKSLVKKLKKT--GQLDELEKAITTQNV-NTKCITIPRSLD 72
L WK+G++ +E W +KA+ +L+KKL K L+ LE A+ Q T+C+TIPRSLD
Sbjct 14 LKWKQGDE---DENWAKKAIDNLMKKLIKHNKQALENLEFALRCQGQQKTECVTIPRSLD 70
Query 73 GRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVE- 131
GRLQ+SHRK LPHVIYCR++RWPDL SHHEL+A+E C F + + ++C+NPYHY+RV
Sbjct 71 GRLQISHRKALPHVIYCRVYRWPDLQSHHELKAIEDCRFCYESGQKDICINPYHYKRVHA 130
Query 132 TPVLPPVLVPRHTEIPAEFPP--------LDDYSHSIPENTNFPAGIEPQSNIPETPPPG 183
T VLPPVLVPR++E P + P ++ +P+N N A + +N P
Sbjct 131 TGVLPPVLVPRYSEKPPQEVPPTLAKFQLMEMSGSRMPQNVNM-ANVNFTANQFHQYNPN 189
Query 184 YLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQR 243
+ E M+ S P P + P E FW ++SYYELN R
Sbjct 190 GIEE--------MDTSQKFDIPPGVPTCLVPFDK--------VWEEQFWATVSYYELNTR 233
Query 244 VGETFHASQPSMTVDGFTDPS-NSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYI--G 300
VGE S ++T+DGFTDP N + LGL SNVNRNA +E TRRHIG GV+L Y+
Sbjct 234 VGEQVKVSSTTITIDGFTDPCINGSKISLGLFSNVNRNATIENTRRHIGNGVKLTYVRSN 293
Query 301 GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGF 360
G +FA+C SDSAIFVQS NCN G+H TV KI C+LKIF+ + F LL +GF
Sbjct 294 GSLFAQCESDSAIFVQSSNCNYINGFHSTTVVKIANKCSLKIFDMEIFRQLLEDCSRRGF 353
Query 361 EAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIR 420
+A + L +M IRMSFVKGWGAEY+RQ VTSTPCWIE+HL+ PL WLD+VL+ MG
Sbjct 354 DASFDLQKMTFIRMSFVKGWGAEYQRQDVTSTPCWIEIHLHAPLAWLDRVLSTMGPTPRP 413
Query 421 CSSVS 425
SS+S
Sbjct 414 ISSIS 418
>sp|P45896|SMA3_CAEEL Dwarfin sma-3 OS=Caenorhabditis elegans
OX=6239 GN=sma-3 PE=1 SV=1
Length=393
Score = 428 bits (1100), Expect = 1e-147, Method: Composition-based stats.
Identities = 178/422 (42%), Positives = 237/422 (56%), Gaps = 51/422 (12%)
Query 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT----GQLDELEKAIT 56
M+ +L P VK+LLGWK GE EEKWCEKAV++LVKKLKK G L++LE +
Sbjct 1 MNGLLHMHGPAVKKLLGWKIGED---EEKWCEKAVEALVKKLKKKNNGCGTLEDLECVLA 57
Query 57 TQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMK 116
N++CITI +SLDGRLQVSH+KGLPHVIYCR+WRWPD+ S HELR+++ C + +
Sbjct 58 NPCTNSRCITIAKSLDGRLQVSHKKGLPHVIYCRVWRWPDISSPHELRSIDTCSYPYESS 117
Query 117 KDE--VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQS 174
+C+NPYHYQR+ P ++ +P+ P S P +G S
Sbjct 118 SKTMYICINPYHYQRLSRP------QGLNSSMPSPQPI------SSPNTIWQSSGSSTAS 165
Query 175 NIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCS 234
P + + GE HQ +P + P W
Sbjct 166 CASSPSPSVFSEDGGEVQVHQ--------------------------RPPPFRHPKSWAQ 199
Query 235 ISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRG 293
I+Y+ELN RVGE F S+TVDG+T+PSNS R CLG L+NVNRN +E TR HIG+G
Sbjct 200 ITYFELNSRVGEVFKLVNLSITVDGYTNPSNSNTRICLGQLTNVNRNGTIENTRMHIGKG 259
Query 294 VRLYYIGGE--VFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAAL 351
++L + + SD +FVQS N N VC+IPP L +F F +
Sbjct 260 IQLDNKEDQMHIMITNNSDMPVFVQSKNTNLMMNMPLVKVCRIPPHSQLCVFEFNLFFQM 319
Query 352 LAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVL 411
L QS N + + +L++ C IR+SFVKGWG +Y RQ VTSTPCW+EL LN PL ++D+ +
Sbjct 320 LEQSCNDS-DGLNELSKHCFIRISFVKGWGEDYPRQDVTSTPCWLELRLNVPLAYIDQKM 378
Query 412 TQ 413
Q
Sbjct 379 KQ 380
>sp|Q9W734|SMAD6_CHICK Mothers against decapentaplegic homolog
6 OS=Gallus gallus OX=9031 GN=SMAD6 PE=2 SV=1
Length=431
Score = 376 bits (966), Expect = 7e-127, Method: Composition-based stats.
Identities = 103/376 (27%), Positives = 164/376 (44%), Gaps = 50/376 (13%)
Query 28 EKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQV-SHRKGLPHV 86
E+ + +L+K+LK+ L+ + C+ + R G L++ + R+ PH+
Sbjct 103 ERELKAVTYALLKRLKERSLHSLLQAVESRGGTPGGCVLVAR---GELRLGAARRPPPHL 159
Query 87 IYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEI 146
+ +L+RWPDL EL+A+ C+ VC NPYH+ R+ P PP
Sbjct 160 LLGKLFRWPDLQHPAELKALCECQSFGAADGPTVCCNPYHFSRLCGPESPPPP------- 212
Query 147 PAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPN 206
YS P + P D S + SPN
Sbjct 213 ---------YSRLSPNDEQKPL-------------------DLSDSTLSYTETEATNSPN 244
Query 207 LSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNS 266
++P S A + D + + WC+++Y+E RVG + + S+++ F D
Sbjct 245 VTPGEFSDASTSPDA-----VKRSHWCNVAYWEHRTRVGRLYTVYEQSVSI--FYDLPQG 297
Query 267 ERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGW 326
FCLG L+ NR+ V TR IG G+ L V+A S+ IFV SP +
Sbjct 298 NGFCLGQLNLENRSETVRRTRSKIGYGILLSKEPDGVWAYNRSEHPIFVNSPTLD-IPNC 356
Query 327 HPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRR 386
V K+ PG ++K+F+ ++ L + + Y ++R+SF KGWG Y R
Sbjct 357 RTLIVRKVMPGYSIKVFDYEKSCLLQHTAELDYADGPYDPN---SVRISFAKGWGPCYSR 413
Query 387 QTVTSTPCWIELHLNG 402
Q +TS PCW+E+ L+
Sbjct 414 QFITSCPCWLEILLSN 429
>sp|O43541|SMAD6_HUMAN Mothers against decapentaplegic homolog
6 OS=Homo sapiens OX=9606 GN=SMAD6 PE=1 SV=2
Length=496
Score = 369 bits (947), Expect = 4e-123, Method: Composition-based stats.
Identities = 106/377 (28%), Positives = 160/377 (42%), Gaps = 51/377 (14%)
Query 28 EKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVI 87
E+ + SL+K+LK+ LE + V C+ +PR+ L++ + P ++
Sbjct 169 EQELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVPRA---DLRLGGQPAPPQLL 225
Query 88 YCRLWRWPDLHSHHELRAMELC-EFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEI 146
RL+RWPDL EL+ + C FA VC NPYH+ R+ P PP R +
Sbjct 226 LGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLS-- 283
Query 147 PAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPN 206
P Y D S + S
Sbjct 284 ---------------------------------PRDEYKPLDLSDSTLSYTETEATNSLI 310
Query 207 LSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNS 266
+P S A + D +P+ WCS++Y+E RVG + ++++ F D
Sbjct 311 TAPGEFSDASMSPDA-----TKPSHWCSVAYWEHRTRVGRLYAVYDQAVSI--FYDLPQG 363
Query 267 ERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGW 326
FCLG L+ R+ +V TR IG G+ L V+A + IFV SP + G
Sbjct 364 SGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDA-PGG 422
Query 327 HPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRR 386
V K+PPG ++K+F+ + + L + Y ++R+SF KGWG Y R
Sbjct 423 RALVVRKVPPGYSIKVFDFER-SGLQHAPEPDAADGPYDPN---SVRISFAKGWGPCYSR 478
Query 387 QTVTSTPCWIELHLNGP 403
Q +TS PCW+E+ LN P
Sbjct 479 QFITSCPCWLEILLNNP 495
>sp|P45897|SMA4_CAEEL Dwarfin sma-4 OS=Caenorhabditis elegans
OX=6239 GN=sma-4 PE=2 SV=1
Length=570
Score = 365 bits (937), Expect = 1e-120, Method: Composition-based stats.
Identities = 155/450 (34%), Positives = 220/450 (49%), Gaps = 75/450 (17%)
Query 11 IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLK-KTGQLDELEKAITTQN-VNTKCITIP 68
I L +++G G++ + KA++SLVKKLK K +LD L A+T+ T C+TI
Sbjct 151 ISHVLQCYQQG---GEDSDFVRKAIESLVKKLKDKRIELDALITAVTSNGKQPTGCVTIQ 207
Query 69 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 128
RSLDGRLQV+ RKG+PHV+Y R+WRWP + S +EL + C+ + + D +C+NPYHY+
Sbjct 208 RSLDGRLQVAGRKGVPHVVYARIWRWPKV-SKNELVKLVQCQTSSD-HPDNICINPYHYE 265
Query 129 RVETPVLPPVLVPRHTE-IPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSE 187
RV + + H E P + L D I+ S+ P TPP
Sbjct 266 RVVSNRITSADQSLHVENSPMKSEYLGDAG-----------VIDSCSDWPNTPP------ 308
Query 188 DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA----FWCSISYYELNQR 243
D+ N P L +S +DL + P WCSI YYEL+
Sbjct 309 -----DNNFNGGFAPDQPQLVTPIISDI--PIDLNQIYVPTPPQLLDNWCSIIYYELDTP 361
Query 244 VGETFHAS---QPSMTVDGFTDP--SNSERFCLGLLSNVNRNAAVELTRRHIGRGVRL-Y 297
+GETF S + VDG DP N R CLG LSNV+R A E R HIGRGV L
Sbjct 362 IGETFKVSARDHGKVIVDGGMDPHGENEGRLCLGALSNVHRTEASEKARIHIGRGVELTA 421
Query 298 YIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCK--IPPGCNLKIFNNQ-EFAALLAQ 354
+ G + S+ IFV+S + +G ++ P + +F+ + + +L +
Sbjct 422 HADGNI--SITSNCKIFVRSGYLDYTHGSEYSSKAHRFTPNESSFTVFDIRWAYMQMLRR 479
Query 355 SVNQ------------------------GFEAVYQLTR-MCTIRMSFVKGWGAEYRRQTV 389
S + V ++ R CTI +SFVK WG Y+R+T+
Sbjct 480 SRSSNEAVRAQAAAVAGYAPMSVMPAIMPDSGVDRMRRDFCTIAISFVKAWGDVYQRKTI 539
Query 390 TSTPCWIELHLNGPLQWLDKVL---TQMGS 416
TPCWIE+ L+ PLQ LD++L +Q GS
Sbjct 540 KETPCWIEVTLHRPLQILDQLLKNSSQFGS 569
>sp|O35182|SMAD6_MOUSE Mothers against decapentaplegic homolog
6 OS=Mus musculus OX=10090 GN=Smad6 PE=1 SV=1
Length=495
Score = 362 bits (930), Expect = 1e-120, Method: Composition-based stats.
Identities = 105/376 (28%), Positives = 161/376 (43%), Gaps = 53/376 (14%)
Query 28 EKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVI 87
E+ + SL+K+LK+ LE + V C+ +PR+ L++ + P ++
Sbjct 170 EQELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVPRA---DLRLGGQPAPPQLL 226
Query 88 YCRLWRWPDLHSHHELRAMELC-EFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEI 146
RL+RWPDL EL+ + C F VC NPYH+ R+ P PP R +
Sbjct 227 LGRLFRWPDLQHAVELKPLCGCHSFTAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSP- 285
Query 147 PAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPN 206
P ++ PLD S + S
Sbjct 286 PDQYKPLD----------------------------------LSDSTLSYTETEATNSLI 311
Query 207 LSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNS 266
+P S A + D +P+ WCS++Y+E RVG + ++++ F D
Sbjct 312 TAPGEFSDASMSPDA-----TKPSHWCSVAYWEHRTRVGRLYAVYDQAVSI--FYDLPQG 364
Query 267 ERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGW 326
FCLG L+ R+ +V TR IG G+ L V+A + IFV SP + G
Sbjct 365 SGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDA-PGG 423
Query 327 HPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRR 386
V K+PPG ++K+F+ + L +A + ++R+SF KGWG Y R
Sbjct 424 RALVVRKVPPGYSIKVFDFERSGLLQH------ADAAHGPYDPHSVRISFAKGWGPCYSR 477
Query 387 QTVTSTPCWIELHLNG 402
Q +TS PCW+E+ LN
Sbjct 478 QFITSCPCWLEILLNN 493
>sp|O15105|SMAD7_HUMAN Mothers against decapentaplegic homolog
7 OS=Homo sapiens OX=9606 GN=SMAD7 PE=1 SV=1
Length=426
Score = 334 bits (856), Expect = 2e-110, Method: Composition-based stats.
Identities = 99/385 (26%), Positives = 166/385 (43%), Gaps = 60/385 (16%)
Query 28 EKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRL-----------Q 76
E + S++KKLK+ L+ + T C+ +P LD RL Q
Sbjct 89 EADLKALTHSVLKKLKERQLELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQ 148
Query 77 VSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLP 136
LP ++ C+++RWPDL E++ + CE + + VC NP+H R+
Sbjct 149 PPSSYSLP-LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRLC----- 202
Query 137 PVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQM 196
+ P D+ ++P ++ P+ P
Sbjct 203 ----ELESPPPPYSRYPMDF-------------LKPTADCPDAVPSS------------- 232
Query 197 NHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMT 256
+ G+ L+P +S + L L+P + + WC ++Y+E RVG + +PS+
Sbjct 233 --AETGGTNYLAPGGLS--DSQLLLEPG---DRSHWCVVAYWEEKTRVGRLYCVQEPSL- 284
Query 257 VDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQ 316
D F D FCLG L++ N++ V+ R IG G++L V+ S IF++
Sbjct 285 -DIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIK 343
Query 317 SPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSF 376
S + V K+ PG ++K F+ ++ +L E + Q T+++SF
Sbjct 344 SATLDNPDS-RTLLVHKVFPGFSIKAFDYEKAYSLQR---PNDHEFMQQPWTGFTVQISF 399
Query 377 VKGWGAEYRRQTVTSTPCWIELHLN 401
VKGWG Y RQ ++S PCW+E+ N
Sbjct 400 VKGWGQCYTRQFISSCPCWLEVIFN 424
>sp|O88406|SMAD7_RAT Mothers against decapentaplegic homolog 7
OS=Rattus norvegicus OX=10116 GN=Smad7 PE=2 SV=2
Length=426
Score = 329 bits (844), Expect = 1e-108, Method: Composition-based stats.
Identities = 99/385 (26%), Positives = 165/385 (43%), Gaps = 60/385 (16%)
Query 28 EKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRL-----------Q 76
E + S++KKLK+ L+ + T C+ +P LD RL Q
Sbjct 89 EADLKALTHSVLKKLKERQLELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPASAQPAQ 148
Query 77 VSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLP 136
LP ++ C+++RWPDL E++ + CE + + VC NP+H R+
Sbjct 149 PPSSYSLP-LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRLC----- 202
Query 137 PVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQM 196
+ P D+ ++P ++ P+ P
Sbjct 203 ----ELESPPPPYSRYPMDF-------------LKPTADCPDAVPSS------------- 232
Query 197 NHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMT 256
G+ L+P +S + L L+P + + WC ++Y+E RVG + +PS+
Sbjct 233 --DETGGTNYLAPGGLS--DSQLLLEPG---DRSHWCVVAYWEEKTRVGRLYCVQEPSL- 284
Query 257 VDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQ 316
D F D FCLG L++ N++ V+ R IG G++L V+ S IF++
Sbjct 285 -DIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIK 343
Query 317 SPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSF 376
S + V K+ PG ++K F+ ++ +L E + Q T+++SF
Sbjct 344 SATLDNPDS-RTLLVHKVFPGFSIKAFDYEKAYSLQR---PNDHEFMQQPWTGFTVQISF 399
Query 377 VKGWGAEYRRQTVTSTPCWIELHLN 401
VKGWG Y RQ ++S PCW+E+ N
Sbjct 400 VKGWGQCYTRQFISSCPCWLEVIFN 424
>sp|O35253|SMAD7_MOUSE Mothers against decapentaplegic homolog
7 OS=Mus musculus OX=10090 GN=Smad7 PE=1 SV=1
Length=426
Score = 329 bits (843), Expect = 2e-108, Method: Composition-based stats.
Identities = 99/385 (26%), Positives = 165/385 (43%), Gaps = 60/385 (16%)
Query 28 EKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRL-----------Q 76
E + S++KKLK+ L+ + T C+ +P LD RL Q
Sbjct 89 EADLKALTHSVLKKLKERQLELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPASAQPAQ 148
Query 77 VSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLP 136
LP ++ C+++RWPDL E++ + CE + + VC NP+H R+
Sbjct 149 PPSSYSLP-LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCNPHHLSRLC----- 202
Query 137 PVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQM 196
+ P D+ ++P + P+ P
Sbjct 203 ----ELESPPPPYSRYPMDF-------------LKPTAGCPDAVPSS------------- 232
Query 197 NHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMT 256
+ G+ L+P +S + L L+P + + WC ++Y+E RVG + +PS+
Sbjct 233 --AETGGTNYLAPGGLS--DSQLLLEPG---DRSHWCVVAYWEEKTRVGRLYCVQEPSL- 284
Query 257 VDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQ 316
D F D FCLG L++ N++ V+ R IG G++L V+ S IF++
Sbjct 285 -DIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIK 343
Query 317 SPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSF 376
S + V K+ PG ++K F+ ++ +L E + Q T+++SF
Sbjct 344 SATLDNPDS-RTLLVHKVFPGFSIKAFDYEKAYSLQR---PNDHEFMQQPWTGFTVQISF 399
Query 377 VKGWGAEYRRQTVTSTPCWIELHLN 401
VKGWG Y RQ ++S PCW+E+ N
Sbjct 400 VKGWGQCYTRQFISSCPCWLEVIFN 424
>sp|P97471|SMAD4_MOUSE Mothers against decapentaplegic homolog
4 OS=Mus musculus OX=10090 GN=Smad4 PE=1 SV=2
Length=551
Score = 323 bits (827), Expect = 2e-104, Method: Composition-based stats.
Identities = 172/528 (33%), Positives = 231/528 (44%), Gaps = 128/528 (24%)
Query 11 IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLD-ELEKAITTQNV-NTKCITIP 68
IV L+ ++G G+ E + ++A++SLVKKLK+ L AITT +KC+TI
Sbjct 19 IVHSLMCHRQG---GESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQ 75
Query 69 RSLDGRLQVSHRKGLPHVIYCRLWRWPDL-----------HSHHELRAMELCEFAF---- 113
R+LDGRLQV+ RKG PHVIY RLWRWPDL +L+ +C +
Sbjct 76 RTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYER 135
Query 114 -------------NMKKDEVCV-NPYHYQRVETPVLPPVLVPRHT--------------E 145
+ V + Y + P LP T
Sbjct 136 VVSPGIDLSGLTLQSNAPSMLVKDEYVHDFEGQPSLPTEGHSIQTIQHPPSNRASTETYS 195
Query 146 IPAEFPPLDDYSHSIPENTNFPAGIEPQS-------------NIPETPPPGYLSEDGETS 192
PA P + + S N P Q I P PG
Sbjct 196 APALLAPAESNATSTTNFPNIPVASTSQPASILAGSHSEGLLQIASGPQPGQQQNGFTAQ 255
Query 193 DHQMNHS---------MDAGSPNL----------------SPNPMSPAHNNLDLQPVTYC 227
+H+ +PNL P P HN L QP
Sbjct 256 PATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPGHYWPVHNELAFQPPISN 315
Query 228 EPA--FWCSISYYELNQRVGETFHA--SQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAV 283
PA +WCSI+Y+E++ +VGETF S P +TVDG+ DPS +RFCLG LSNV+R A+
Sbjct 316 HPAPEYWCSIAYFEMDVQVGETFKVPSSCPVVTVDGYVDPSGGDRFCLGQLSNVHRTEAI 375
Query 284 ELTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHP-ATVCKIPPGCNLK 341
E R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P V KI P +K
Sbjct 376 ERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIK 435
Query 342 IFNNQE-----------------------------------FAALLAQSVNQGFEAVYQL 366
+F+ ++ A ++ S G V L
Sbjct 436 VFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGI-GVDDL 494
Query 367 TRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQM 414
R+C +RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL M
Sbjct 495 RRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 542
>sp|O70437|SMAD4_RAT Mothers against decapentaplegic homolog 4
OS=Rattus norvegicus OX=10116 GN=Smad4 PE=1 SV=1
Length=552
Score = 322 bits (825), Expect = 4e-104, Method: Composition-based stats.
Identities = 172/529 (33%), Positives = 231/529 (44%), Gaps = 129/529 (24%)
Query 11 IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLD-ELEKAITTQNV-NTKCITIP 68
IV L+ ++G G+ E + ++A++SLVKKLK+ L AITT +KC+TI
Sbjct 19 IVHSLMCHRQG---GESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQ 75
Query 69 RSLDGRLQVSHRKGLPHVIYCRLWRWPDL-----------HSHHELRAMELCEFAF---- 113
R+LDGRLQV+ RKG PHVIY RLWRWPDL +L+ +C +
Sbjct 76 RTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYER 135
Query 114 ---------------NMKKDEVCVNPYHYQRVETPVLPPVLVPRHT-------------- 144
N + + Y + P LP T
Sbjct 136 VVSPGIDLSGLTLQSNAPPSMLVKDEYVHDFEGQPSLPTEGHSIQTIQHPPSNRASTETY 195
Query 145 EIPAEFPPLDDYSHSIPENTNFPAGIEPQS-------------NIPETPPPGYLSEDGET 191
PA P + + S N P Q I P PG
Sbjct 196 SAPALLAPSESNATSTTNFPNIPVASTSQPASILAGSHSEGLLQIASGPQPGQQQNGFTA 255
Query 192 SDHQMNHS---------MDAGSPNL----------------SPNPMSPAHNNLDLQPVTY 226
+H+ +PNL P P HN L QP
Sbjct 256 QPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPGHYWPVHNELAFQPPIS 315
Query 227 CEPA--FWCSISYYELNQRVGETFHA--SQPSMTVDGFTDPSNSERFCLGLLSNVNRNAA 282
PA +WCSI+Y+E++ +VGETF S P +TVDG+ DPS +RFCLG LSNV+R A
Sbjct 316 NHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEA 375
Query 283 VELTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHP-ATVCKIPPGCNL 340
+E R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P V KI P +
Sbjct 376 IERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYI 435
Query 341 KIFNNQE-----------------------------------FAALLAQSVNQGFEAVYQ 365
K+F+ ++ A ++ S G V
Sbjct 436 KVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGI-GVDD 494
Query 366 LTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQM 414
L R+C +RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL M
Sbjct 495 LRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 543
>sp|Q21733|DAF8_CAEEL Smad protein daf-8 OS=Caenorhabditis elegans
OX=6239 GN=daf-8 PE=1 SV=1
Length=546
Score = 277 bits (709), Expect = 7e-87, Method: Composition-based stats.
Identities = 84/204 (41%), Positives = 114/204 (56%), Gaps = 4/204 (2%)
Query 224 VTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFT----DPSNSERFCLGLLSNVNR 279
V Y E W + YYE +GE +DGFT D RF LG +N NR
Sbjct 341 VEYEESPSWLKLIYYEEGTMIGEKADVEGHHCLIDGFTASRTDSETRSRFSLGWYNNPNR 400
Query 280 NAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCN 339
+ R IG+GVR Y + GEV+ E L + +FVQS N + G+ TV K+PP
Sbjct 401 SPQTAEVRGLIGKGVRFYLLAGEVYVENLCNIPVFVQSIGANMKNGFQLNTVSKLPPTGT 460
Query 340 LKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELH 399
+K+F+ + F+ L + + ++ VY L+RMCT+R+SF KGWG YRR TV +P W + H
Sbjct 461 MKVFDMRLFSKQLRTAAEKTYQDVYCLSRMCTVRVSFCKGWGEHYRRSTVLRSPVWFQAH 520
Query 400 LNGPLQWLDKVLTQMGSPSIRCSS 423
LN P+ W+D VLT MG+P CSS
Sbjct 521 LNNPMHWVDSVLTCMGAPPRICSS 544
Score = 137 bits (345), Expect = 2e-34, Method: Composition-based stats.
Identities = 30/124 (24%), Positives = 57/124 (46%), Gaps = 5/124 (4%)
Query 30 WCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYC 89
W K + L + KK + A+ + T+C + + +L + + + V+
Sbjct 36 WALKVTRLLSRVAKKHQCFEAFYDAVIKGDPKTRCCP---AHNEKLIGNFGRAIMCVL-- 90
Query 90 RLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAE 149
R +R+P + +++++ C AFN VC+NPYHY+ VE P + + E+
Sbjct 91 RAFRFPVIRYESQVKSILTCRHAFNSHSRNVCLNPYHYRWVELPTCQVPPIIVNKELDYG 150
Query 150 FPPL 153
PP+
Sbjct 151 EPPI 154
>sp|Q1HE26|SMAD4_BOVIN Mothers against decapentaplegic homolog
4 OS=Bos taurus OX=9913 GN=SMAD4 PE=2 SV=1
Length=553
Score = 251 bits (640), Expect = 1e-76, Method: Composition-based stats.
Identities = 110/318 (35%), Positives = 148/318 (47%), Gaps = 42/318 (13%)
Query 138 VLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMN 197
+L H+E + T PA S T +
Sbjct 228 ILAGSHSEGLLQIASGPQPGQQQNGFTGQPATYHHNSTTTWTGGRTAPYTPNLPHHQNGH 287
Query 198 HSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA--FWCSISYYELNQRVGETFHA--SQP 253
P + P HN L QP PA +WCSI+Y+E++ +VGETF S P
Sbjct 288 LQHHPPMPPHPGHYWPPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCP 347
Query 254 SMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG-GEVFAECLSDSA 312
+TVDG+ DPS +RFCLG LSNV+R A+E R HIG+GV+L G G+V+ CLSD A
Sbjct 348 IVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHA 407
Query 313 IFVQSPNCNQRYGWHP-ATVCKIPPGCNLKIFNNQE------------------------ 347
+FVQS ++ G P V KI P +K+F+ ++
Sbjct 408 VFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVA 467
Query 348 -----------FAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWI 396
A ++ S G V L R+C +RMSFVKGWG +Y RQ++ TPCWI
Sbjct 468 GNIPGPGSVGGIAPAISLSAAAGI-GVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWI 526
Query 397 ELHLNGPLQWLDKVLTQM 414
E+HL+ LQ LD+VL M
Sbjct 527 EIHLHRALQLLDEVLHTM 544
Score = 179 bits (453), Expect = 2e-49, Method: Composition-based stats.
Identities = 79/221 (36%), Positives = 115/221 (52%), Gaps = 7/221 (3%)
Query 11 IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLD-ELEKAITTQNV-NTKCITIP 68
IV L+ ++G G+ E + ++A++SLVKKLK+ L AITT +KC+TI
Sbjct 19 IVHSLMCHRQG---GESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQ 75
Query 69 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 128
R+LDGRLQV+ RKG PHVIY RLWRWPDL +EL+ ++ C++AF++K D VCVNPYHY+
Sbjct 76 RTLDGRLQVAGRKGFPHVIYARLWRWPDL-HKNELKHVKYCQYAFDLKCDSVCVNPYHYE 134
Query 129 RVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSED 188
RV +P + + + P D+Y H + I P +E
Sbjct 135 RVVSPGIDLSGLTLQSNAPPSMLVKDEYVHDFEGQPSLSTEGHSIQTIQHPPSNRASTET 194
Query 189 GETSDHQMNHSMDAGSPNLSPN-PMSPAHNNLDLQPVTYCE 228
T +A S PN P++ + ++ E
Sbjct 195 YSTPALLAPSESNATSTTNFPNIPVASTSQPASILAGSHSE 235
>sp|Q9GKQ9|SMAD4_PIG Mothers against decapentaplegic homolog 4
OS=Sus scrofa OX=9823 GN=SMAD4 PE=2 SV=1
Length=552
Score = 251 bits (640), Expect = 2e-76, Method: Composition-based stats.
Identities = 113/318 (36%), Positives = 149/318 (47%), Gaps = 43/318 (14%)
Query 138 VLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMN 197
+L H+E + T PA S T HQ
Sbjct 228 ILAGSHSEGLLQIASGPQPGQQQNGFTGQPATYHHNSTTTWTGSRT-APYPPNLPHHQNG 286
Query 198 HSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA--FWCSISYYELNQRVGETFHA--SQP 253
H P P HN L QP PA +WCSI+Y+E++ +VGETF S P
Sbjct 287 HLQHHPPMPPHPGHYWPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCP 346
Query 254 SMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG-GEVFAECLSDSA 312
+TVDG+ DPS +RFCLG LSNV+R A+E R HIG+GV+L G G+V+ CLSD A
Sbjct 347 IVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHA 406
Query 313 IFVQSPNCNQRYGWHP-ATVCKIPPGCNLKIFNNQE------------------------ 347
+FVQS ++ G P V KI P +K+F+ ++
Sbjct 407 VFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVA 466
Query 348 -----------FAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWI 396
A ++ S G V L R+C +RMSFVKGWG +Y RQ++ TPCWI
Sbjct 467 GNIPGPGSVGGIAPAISLSAAAGI-GVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWI 525
Query 397 ELHLNGPLQWLDKVLTQM 414
E+HL+ LQ LD+VL M
Sbjct 526 EIHLHRALQLLDEVLHTM 543
Score = 178 bits (451), Expect = 4e-49, Method: Composition-based stats.
Identities = 79/221 (36%), Positives = 116/221 (52%), Gaps = 7/221 (3%)
Query 11 IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLD-ELEKAITTQNV-NTKCITIP 68
IV L+ ++G G+ E + ++A++SLVKKLK+ L AITT +KC+TI
Sbjct 19 IVHSLMCHRQG---GESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQ 75
Query 69 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 128
R+LDGRLQV+ RKG PHVIY RLWRWPDL +EL+ ++ C++AF++K D VCVNPYHY+
Sbjct 76 RTLDGRLQVAGRKGFPHVIYARLWRWPDL-HKNELKHVKYCQYAFDLKCDSVCVNPYHYE 134
Query 129 RVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSED 188
RV +P + + + P+ D+Y H + I P +E
Sbjct 135 RVVSPGIDLSGLTLQSNAPSGMLVKDEYVHDFEGQPSLATEGHSIQTIQHPPSNRASTET 194
Query 189 GETSDHQMNHSMDAGSPNLSPN-PMSPAHNNLDLQPVTYCE 228
T +A S PN P++ + ++ E
Sbjct 195 YSTPALLAPSESNATSTTNFPNIPVASTSQPASILAGSHSE 235
>sp|Q13485|SMAD4_HUMAN Mothers against decapentaplegic homolog
4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1
Length=552
Score = 248 bits (634), Expect = 9e-76, Method: Composition-based stats.
Identities = 101/242 (42%), Positives = 134/242 (55%), Gaps = 42/242 (17%)
Query 214 PAHNNLDLQPVTYCEPA--FWCSISYYELNQRVGETFHA--SQPSMTVDGFTDPSNSERF 269
P HN L QP PA +WCSI+Y+E++ +VGETF S P +TVDG+ DPS +RF
Sbjct 303 PVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRF 362
Query 270 CLGLLSNVNRNAAVELTRRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHP 328
CLG LSNV+R A+E R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P
Sbjct 363 CLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAP 422
Query 329 -ATVCKIPPGCNLKIFNNQE-----------------------------------FAALL 352
V KI P +K+F+ ++ A +
Sbjct 423 GDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAI 482
Query 353 AQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLT 412
+ S G V L R+C +RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL
Sbjct 483 SLSAAAGI-GVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLH 541
Query 413 QM 414
M
Sbjct 542 TM 543
Score = 178 bits (451), Expect = 5e-49, Method: Composition-based stats.
Identities = 79/232 (34%), Positives = 117/232 (50%), Gaps = 17/232 (7%)
Query 11 IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLD-ELEKAITTQNV-NTKCITIP 68
IV L+ ++G G+ E + ++A++SLVKKLK+ L AITT +KC+TI
Sbjct 19 IVHSLMCHRQG---GESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQ 75
Query 69 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 128
R+LDGRLQV+ RKG PHVIY RLWRWPDL +EL+ ++ C++AF++K D VCVNPYHY+
Sbjct 76 RTLDGRLQVAGRKGFPHVIYARLWRWPDL-HKNELKHVKYCQYAFDLKCDSVCVNPYHYE 134
Query 129 RVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPP------- 181
RV +P + + + P+ D+Y H + I P
Sbjct 135 RVVSPGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQTIQHPPSNRASTET 194
Query 182 ---PGYLSEDGETSDHQMNHSMDAGSPNLSPNP-MSPAHNNLDLQPVTYCEP 229
P L+ + N + P + +H+ LQ + +P
Sbjct 195 YSTPALLAPSESNATSTANFPNIPVASTSQPASILGGSHSEGLLQIASGPQP 246
>sp|F5GUE5|DAF14_CAEEL Smad-related protein daf-14 OS=Caenorhabditis
elegans OX=6239 GN=daf-14 PE=1 SV=1
Length=331
Score = 240 bits (611), Expect = 7e-75, Method: Composition-based stats.
Identities = 76/267 (28%), Positives = 119/267 (45%), Gaps = 8/267 (3%)
Query 152 PLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNP 211
P + ++P N P + ++ S+ S+ +P +
Sbjct 53 PASINNPNMPINDWLEDAPMPDCYNVPSTSTDENNDPFPFSNISSQSSLKPKTPEKAVVE 112
Query 212 MSPAHNN-LDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFC 270
+ P N LD +P E WC+I YYEL R+G+ F A P++T+DG T S+ R
Sbjct 113 VRPTGNEMLDPEPKYPKEEKPWCTIFYYELTVRLGKAFEAKVPTITIDGATGASDECRMS 172
Query 271 LGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPAT 330
L + +RN+ R +G G++L Y GE++ L+D +FVQ P NQ
Sbjct 173 LTSQPS-SRNSKSSQIRNTVGAGIQLAYENGELWLTVLTDQIVFVQCPFLNQTLNKPLKY 231
Query 331 VCKIPPGCN---LKIFNNQEFAALLAQSVNQGFEAVYQLTRM---CTIRMSFVKGWGAEY 384
V ++ + +KIF+ ++F ++ E RM IR+SF KG+G Y
Sbjct 232 VFRLQNKGDQKRMKIFDKEQFEQEKTLALGPLTEKEVADERMRIFSNIRVSFCKGFGETY 291
Query 385 RRQTVTSTPCWIELHLNGPLQWLDKVL 411
R V + PCWIE+ L+ P D V
Sbjct 292 SRLKVVNLPCWIEIILHEPADEYDTVF 318
>sp|Q95QI7|DAF3_CAEEL Smad protein daf-3 OS=Caenorhabditis elegans
OX=6239 GN=daf-3 PE=1 SV=1
Length=892
Score = 186 bits (471), Expect = 2e-50, Method: Composition-based stats.
Identities = 79/365 (22%), Positives = 126/365 (35%), Gaps = 51/365 (14%)
Query 94 WPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV--ETPVLPPVLVPRHTEIPAEFP 151
+PD H + + + + N + P H +V + P+ PVL P +
Sbjct 505 YPDFHHPFNQQPHQPPQLSQNHTSQQGSHQPGHQGQVPNDPPISRPVLQPSTVTLDVFRR 564
Query 152 PLDDY--SHSIPENTNFPAGIEPQSNIP----ETPPPGYL-----SEDGETSDHQMNHSM 200
+ + I SN ++P G DGE ++ M
Sbjct 565 YCRQTFGNRFFEGESEQSGAIIRSSNKFIEEFDSPICGVTVVRPRMTDGEVLENIMPEDA 624
Query 201 D-AGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDG 259
S + P W +I YYE N ++GE S+ + VDG
Sbjct 625 PYHDICKFILRLTSESVTFSGEGPEVSDLNEKWGTIVYYEKNLQIGEK-KCSRGNFHVDG 683
Query 260 -FTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRL-YYIGGEVFAECLSDSAIFVQS 317
F N R+ LGL N R R+ I G+R Y G V+ + +FV S
Sbjct 684 GFICSEN--RYSLGLEPNPIREPVAFKVRKAIVDGIRFSYKKDGSVWLQNRMKYPVFVTS 741
Query 318 PNCN-QRYGWHPATVCKIPPGCNLKIFNN-------------QEFAALLAQSVNQGFEAV 363
+ Q G V K+ ++K F ++ A + Q +
Sbjct 742 GYLDEQSGGLKKDKVHKVYGCASIKTFGFNVSKQIIRDALLSKQMATMYLQGKLTPMNYI 801
Query 364 YQ-----------------LTRMCTIRMSFVKGWGAEYR-RQTVTSTPCWIELHLNGPLQ 405
Y+ L + C +R+SF KG+G Y R ++ P WIEL +N
Sbjct 802 YEKKTQEELRREATRTTDSLAKYCCVRVSFCKGFGEAYPERPSIHDCPVWIELKINIAYD 861
Query 406 WLDKV 410
++D +
Sbjct 862 FMDSI 866
Score = 181 bits (460), Expect = 6e-49, Method: Composition-based stats.
Identities = 78/219 (36%), Positives = 111/219 (51%), Gaps = 25/219 (11%)
Query 23 QNGQEEKWCEKAVKSLVKKLKKTGQLDE--LEKAITTQNVNTKCITIPRSLDGRLQVSHR 80
+N + ++ +KA +SLVKKLK + ++ ++ T CITIPR+LDGRLQV R
Sbjct 233 KNNIDREFDQKACESLVKKLKDKKNDLQNLIDVVLSKGTKYTGCITIPRTLDGRLQVHGR 292
Query 81 KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV---------- 130
KG PHV+Y +LWR+ ++ + +E R ++ C+ AF MK D VCVNPYHY+ V
Sbjct 293 KGFPHVVYGKLWRFNEM-TKNETRHVDHCKHAFEMKSDMVCVNPYHYEIVIGTMIVGQRD 351
Query 131 -ETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEP---QSNIPETPPPGYLS 186
+ +PP HT P P+DD S IP PA I P + P P L
Sbjct 352 HDNRDMPPPHQRYHT--PGRQDPVDDMSRFIP-----PASIRPPPMNMHTRPQPMPQQLP 404
Query 187 EDGETSDHQMNHSMDAGSPNLSPNPMSP-AHNNLDLQPV 224
G T H + H P ++P H L++ P+
Sbjct 405 SVGATFAHPLPHQAPHNPGVSHPYSIAPQTHYPLNMNPI 443
>sp|Q9JKS6|PCLO_RAT Protein piccolo OS=Rattus norvegicus OX=10116
GN=Pclo PE=1 SV=1
Length=5085
Score = 44.0 bits (102), Expect = 0.003, Method: Composition-based stats.
Identities = 20/101 (20%), Positives = 24/101 (24%), Gaps = 5/101 (5%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENT-NFPAGIEPQSNIPETPPPGYLSEDGE 190
P P P T+ + P P T P P P+ P P
Sbjct 381 GPGKTPAQQPGPTKPSPQQPIPAKPQPQQPVATKTQPQQSAPAKPQPQQPAPAKPQPQQP 440
Query 191 TSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
T P P P QP T +P
Sbjct 441 TPAKPQPQP----PTPAKPQPQPPTATKPQPQPPTATKPHH 477
Score = 40.5 bits (93), Expect = 0.038, Method: Composition-based stats.
Identities = 25/143 (17%), Positives = 39/143 (27%), Gaps = 6/143 (4%)
Query 95 PDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLD 154
P + + +E + + P H + PV P P + PA+ P
Sbjct 305 PPAKTPGQQAGLEKTSSSQQPGPKSLAQTPGHGKFPLGPVKSPAQQPGTAKHPAQQPGPQ 364
Query 155 DYSH-----SIPENTNFPAGIEPQSNIPETPPPGY-LSEDGETSDHQMNHSMDAGSPNLS 208
+ P + P Q P P P + + + S
Sbjct 365 TAAKVPGPTKTPAQQSGPGKTPAQQPGPTKPSPQQPIPAKPQPQQPVATKTQPQQSAPAK 424
Query 209 PNPMSPAHNNLDLQPVTYCEPAF 231
P P PA Q T +P
Sbjct 425 PQPQQPAPAKPQPQQPTPAKPQP 447
>sp|Q92985|IRF7_HUMAN Interferon regulatory factor 7 OS=Homo sapiens
OX=9606 GN=IRF7 PE=1 SV=2
Length=503
Score = 41.3 bits (95), Expect = 0.014, Method: Composition-based stats.
Identities = 43/224 (19%), Positives = 69/224 (31%), Gaps = 26/224 (12%)
Query 141 PRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSM 200
P T+ P E + + PAG + TP PG T + S
Sbjct 205 PVPTKAPGEGQEGLPLTGACAGGPGLPAGELYGWAVETTPSPGPQPAALTTGEAAAPESP 264
Query 201 DAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWC--SISYYELNQRVGETFHASQPSMTV- 257
P LSP+P + EP+ Y+ + + PS T
Sbjct 265 HQAEPYLSPSPSACT---------AVQEPSPGALDVTIMYKGRTVLQKV--VGHPSCTFL 313
Query 258 -------DGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSD 310
TDP L + + E RH+ G+ L G +++A +
Sbjct 314 YGPPDPAVRATDPQQVAFPSPAELPDQKQLRYTEELLRHVAPGLHLELRGPQLWARRMGK 373
Query 311 SAIFVQSPNCNQRYG--WHPATVCKIPPGCNLKIFNNQEFAALL 352
++ + G C +P C+ IF+ + F L
Sbjct 374 CKVYWEVGG---PPGSASPSTPACLLPRNCDTPIFDFRVFFQEL 414
>sp|A8AUS1|SSPB_STRGC Streptococcal surface protein B OS=Streptococcus
gordonii (strain Challis / ATCC 35105 / BCRC 15272
/ CH1 / DL1 / V288) OX=467705 GN=sspB PE=1 SV=1
Length=1499
Score = 41.7 bits (96), Expect = 0.015, Method: Composition-based stats.
Identities = 20/104 (19%), Positives = 30/104 (29%), Gaps = 5/104 (5%)
Query 131 ETPVLPPVLVPRHTEIPAEFPPLDDYSHSI---PENTNFPAGIEPQSNIPETPPPGYLSE 187
E PPV P E P + + P + P IP+ P P E
Sbjct 786 ENEPTPPVKTPDQPEPSKPEEPTYETEKPLEPAPVAPTYENEPTPPVKIPDQPEPSKPEE 845
Query 188 DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
++ + +P P P +P EP +
Sbjct 846 PTYETEKPLEP--APVAPTYENEPTPPVKTPDQPEPSKPEEPTY 887
Score = 37.1 bits (84), Expect = 0.35, Method: Composition-based stats.
Identities = 34/161 (21%), Positives = 47/161 (29%), Gaps = 25/161 (16%)
Query 131 ETPVLPPVLVPRHTEIPAEFPPLDDYSHSI---PENTNFPAGIEPQSNIPETPPPGYLSE 187
E PPV +P E P + + P + P P+ P P E
Sbjct 825 ENEPTPPVKIPDQPEPSKPEEPTYETEKPLEPAPVAPTYENEPTPPVKTPDQPEPSKPEE 884
Query 188 DGETSDHQMNHSMDAGSPNLSPNPMSPA----HNNLDLQPVTYCEPAFW----------- 232
T D + L P+ P +++L QP E
Sbjct 885 P--TYDPLPTPPLAPTPKQLPTPPVVPTVHFHYSSLLAQPQINKEIKNEDGVDIDRTLVA 942
Query 233 -CSISYYELNQRVGETFHASQPSMTVDGFTDP-SNSERFCL 271
SI +EL E A +P T DP +F L
Sbjct 943 KQSIVKFELKT---EALTAGRPKTTSFVLVDPLPTGYKFDL 980
>sp|Q9UJ55|MAGL2_HUMAN MAGE-like protein 2 OS=Homo sapiens OX=9606
GN=MAGEL2 PE=1 SV=2
Length=1249
Score = 41.3 bits (95), Expect = 0.017, Method: Composition-based stats.
Identities = 18/93 (19%), Positives = 20/93 (22%), Gaps = 2/93 (2%)
Query 136 PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQ 195
PP P P P P P G P P + G H
Sbjct 143 PPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHP 202
Query 196 MN--HSMDAGSPNLSPNPMSPAHNNLDLQPVTY 226
M P +P P QP
Sbjct 203 PPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAP 235
Score = 36.3 bits (82), Expect = 0.66, Method: Composition-based stats.
Identities = 17/96 (18%), Positives = 24/96 (25%), Gaps = 4/96 (4%)
Query 136 PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQ 195
PP P + + P P P + + PPPG
Sbjct 113 PPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPP----PGTPMSHPPPPGTPMAHPPPPGTP 168
Query 196 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
M H G+P + P P + P
Sbjct 169 MAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPP 204
Score = 36.3 bits (82), Expect = 0.73, Method: Composition-based stats.
Identities = 24/107 (22%), Positives = 28/107 (26%), Gaps = 10/107 (9%)
Query 133 PVLPPVLVPRHTEI--PAEFPPLDDYSHSIPENTNFPAGIEPQSNIP--ETPPPG----Y 184
P P VL+ + P PP S P P P P PPPG +
Sbjct 122 PPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVH 181
Query 185 LSEDGETSDHQMN--HSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEP 229
G H M P +P P P P
Sbjct 182 PPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTP 228
Score = 34.0 bits (76), Expect = 3.0, Method: Composition-based stats.
Identities = 21/91 (23%), Positives = 26/91 (29%), Gaps = 8/91 (9%)
Query 136 PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQ 195
PP P P P + P P G P ++ P P T
Sbjct 163 PPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPG-TPMAHPPPPGTPMAHPPPPGT---- 217
Query 196 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTY 226
M P +P PA L QP+T
Sbjct 218 ---PMAHPPPPGTPMAQPPAPGVLMAQPLTP 245
Score = 34.0 bits (76), Expect = 3.4, Method: Composition-based stats.
Identities = 16/102 (16%), Positives = 20/102 (20%), Gaps = 6/102 (6%)
Query 136 PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQ 195
PP P P P P P G P P G
Sbjct 183 PPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQP 242
Query 196 MN------HSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
+ G+P + P P + P
Sbjct 243 LTPGVLMVQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGP 284
>sp|A8AUS0|SSPA_STRGC Streptococcal surface protein A OS=Streptococcus
gordonii (strain Challis / ATCC 35105 / BCRC 15272
/ CH1 / DL1 / V288) OX=467705 GN=sspA PE=1 SV=1
Length=1575
Score = 40.9 bits (94), Expect = 0.024, Method: Composition-based stats.
Identities = 19/104 (18%), Positives = 29/104 (28%), Gaps = 5/104 (5%)
Query 131 ETPVLPPVLVPRHTEIPAEFPPLDDYSHSI---PENTNFPAGIEPQSNIPETPPPGYLSE 187
E PPV P E P + + P + P P+ P P E
Sbjct 859 ENEPTPPVKTPDQPEPSKPEEPTYETEKPLEPAPVVPTYENEPTPPVKTPDQPEPSKPEE 918
Query 188 DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
++ + +P P P +P EP +
Sbjct 919 PTYETEKPLEP--APVAPTYENEPTPPVKTPDQPEPSKPEEPTY 960
Score = 37.8 bits (86), Expect = 0.25, Method: Composition-based stats.
Identities = 17/101 (17%), Positives = 25/101 (25%), Gaps = 6/101 (6%)
Query 131 ETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGE 190
E P P PL+ P + P P+ P P E
Sbjct 827 EKPTPPVAPTEPQAPTYEVEKPLE----PAPVAPTYENEPTPPVKTPDQPEPSKPEEPTY 882
Query 191 TSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
++ + P P P +P EP +
Sbjct 883 ETEKPLEP--APVVPTYENEPTPPVKTPDQPEPSKPEEPTY 921
>sp|P16952|SSPB_STRGN Agglutinin receptor OS=Streptococcus gordonii
OX=1302 GN=sspB PE=1 SV=2
Length=1500
Score = 40.5 bits (93), Expect = 0.031, Method: Composition-based stats.
Identities = 19/104 (18%), Positives = 31/104 (30%), Gaps = 5/104 (5%)
Query 131 ETPVLPPVLVPRHTEIPAEFPPLDDYSHSI---PENTNFPAGIEPQSNIPETPPPGYLSE 187
E PPV P E P + + P ++ P P+ P P E
Sbjct 787 ENEPTPPVKTPDQPEPSKPEEPTYETEKPLEPAPVAPSYENEPTPPVKTPDQPEPSKPEE 846
Query 188 DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
++ + +P+ P P +P EP +
Sbjct 847 PNYETEKPLEP--APVAPSYENEPTPPVKIPDQPEPSKPEEPTY 888
>sp|Q06852|SLAP1_ACET2 Cell surface glycoprotein 1 OS=Acetivibrio
thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 /
NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119
GN=olpB PE=3 SV=2
Length=2313
Score = 40.2 bits (92), Expect = 0.040, Method: Composition-based stats.
Identities = 22/104 (21%), Positives = 33/104 (32%), Gaps = 4/104 (4%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYS-HSIPENTNFPAGIEPQSNIP---ETPPPGYLSE 187
+ P P +E P E P D S P + P+ S+ P + P P E
Sbjct 1489 SDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPE 1548
Query 188 DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
+ +D + + P S P +P EP
Sbjct 1549 EPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTP 1592
Score = 40.2 bits (92), Expect = 0.040, Method: Composition-based stats.
Identities = 22/104 (21%), Positives = 33/104 (32%), Gaps = 4/104 (4%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYS-HSIPENTNFPAGIEPQSNIP---ETPPPGYLSE 187
+ P P +E P E P D S P + P+ S+ P + P P E
Sbjct 1857 SDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPE 1916
Query 188 DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
+ +D + + P S P +P EP
Sbjct 1917 EPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTP 1960
Score = 39.0 bits (89), Expect = 0.090, Method: Composition-based stats.
Identities = 21/103 (20%), Positives = 32/103 (31%), Gaps = 4/103 (4%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYS-HSIPENTNFPAGIEPQSNIP---ETPPPGYLSE 187
+ P P +E P E P D S P + P+ S+ P + P P E
Sbjct 1403 SDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPE 1462
Query 188 DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
+ +D + + P S P +P P
Sbjct 1463 EPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPE 1505
Score = 39.0 bits (89), Expect = 0.090, Method: Composition-based stats.
Identities = 21/103 (20%), Positives = 32/103 (31%), Gaps = 4/103 (4%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYS-HSIPENTNFPAGIEPQSNIP---ETPPPGYLSE 187
+ P P +E P E P D S P + P+ S+ P + P P E
Sbjct 1446 SDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPE 1505
Query 188 DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
+ +D + + P S P +P P
Sbjct 1506 EPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPE 1548
Score = 39.0 bits (89), Expect = 0.090, Method: Composition-based stats.
Identities = 21/103 (20%), Positives = 32/103 (31%), Gaps = 4/103 (4%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYS-HSIPENTNFPAGIEPQSNIP---ETPPPGYLSE 187
+ P P +E P E P D S P + P+ S+ P + P P E
Sbjct 1642 SDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPE 1701
Query 188 DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
+ +D + + P S P +P P
Sbjct 1702 EPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPE 1744
Score = 39.0 bits (89), Expect = 0.090, Method: Composition-based stats.
Identities = 21/103 (20%), Positives = 32/103 (31%), Gaps = 4/103 (4%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYS-HSIPENTNFPAGIEPQSNIP---ETPPPGYLSE 187
+ P P +E P E P D S P + P+ S+ P + P P E
Sbjct 1685 SDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPE 1744
Query 188 DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
+ +D + + P S P +P P
Sbjct 1745 EPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPE 1787
Score = 39.0 bits (89), Expect = 0.090, Method: Composition-based stats.
Identities = 21/103 (20%), Positives = 32/103 (31%), Gaps = 4/103 (4%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYS-HSIPENTNFPAGIEPQSNIP---ETPPPGYLSE 187
+ P P +E P E P D S P + P+ S+ P + P P E
Sbjct 1728 SDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPE 1787
Query 188 DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
+ +D + + P S P +P P
Sbjct 1788 EPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPE 1830
Score = 39.0 bits (89), Expect = 0.090, Method: Composition-based stats.
Identities = 21/103 (20%), Positives = 32/103 (31%), Gaps = 4/103 (4%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYS-HSIPENTNFPAGIEPQSNIP---ETPPPGYLSE 187
+ P P +E P E P D S P + P+ S+ P + P P E
Sbjct 1771 SDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPE 1830
Query 188 DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
+ +D + + P S P +P P
Sbjct 1831 EPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPE 1873
Score = 39.0 bits (89), Expect = 0.090, Method: Composition-based stats.
Identities = 21/103 (20%), Positives = 32/103 (31%), Gaps = 4/103 (4%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYS-HSIPENTNFPAGIEPQSNIP---ETPPPGYLSE 187
+ P P +E P E P D S P + P+ S+ P + P P E
Sbjct 1814 SDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPE 1873
Query 188 DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
+ +D + + P S P +P P
Sbjct 1874 EPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPE 1916
Score = 38.6 bits (88), Expect = 0.12, Method: Composition-based stats.
Identities = 24/106 (23%), Positives = 34/106 (32%), Gaps = 8/106 (8%)
Query 131 ETPVLP-PVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPP----PGYL 185
ETP P P P P++ P D P + P+ EP + TP P
Sbjct 1545 ETPEEPIPTDTPSDEPTPSDEPTPSD--EPTPSDEPTPSD-EPTPSDEPTPSDEPTPSET 1601
Query 186 SEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
E+ +D + + P S P +P EP
Sbjct 1602 PEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTP 1647
Score = 38.6 bits (88), Expect = 0.12, Method: Composition-based stats.
Identities = 24/106 (23%), Positives = 34/106 (32%), Gaps = 8/106 (8%)
Query 131 ETPVLP-PVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPP----PGYL 185
ETP P P P P++ P D P + P+ EP + TP P
Sbjct 1913 ETPEEPIPTDTPSDEPTPSDEPTPSD--EPTPSDEPTPSD-EPTPSDEPTPSDEPTPSET 1969
Query 186 SEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
E+ +D + + P S P +P EP
Sbjct 1970 PEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTP 2015
Score = 35.1 bits (79), Expect = 1.6, Method: Composition-based stats.
Identities = 14/99 (14%), Positives = 28/99 (28%), Gaps = 0/99 (0%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGET 191
+ P P ++ P ++ + + EP + TP D T
Sbjct 1397 SDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPT 1456
Query 192 SDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
+ +P+ P P + + P P+
Sbjct 1457 PSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 1495
Score = 35.1 bits (79), Expect = 1.6, Method: Composition-based stats.
Identities = 14/99 (14%), Positives = 28/99 (28%), Gaps = 0/99 (0%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGET 191
+ P P ++ P ++ + + EP + TP D T
Sbjct 1440 SDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPT 1499
Query 192 SDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
+ +P+ P P + + P P+
Sbjct 1500 PSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 1538
Score = 35.1 bits (79), Expect = 1.6, Method: Composition-based stats.
Identities = 14/99 (14%), Positives = 28/99 (28%), Gaps = 0/99 (0%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGET 191
+ P P ++ P ++ + + EP + TP D T
Sbjct 1483 SDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPT 1542
Query 192 SDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
+ +P+ P P + + P P+
Sbjct 1543 PSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 1581
Score = 35.1 bits (79), Expect = 1.6, Method: Composition-based stats.
Identities = 14/99 (14%), Positives = 28/99 (28%), Gaps = 0/99 (0%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGET 191
+ P P ++ P ++ + + EP + TP D T
Sbjct 1636 SDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPT 1695
Query 192 SDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
+ +P+ P P + + P P+
Sbjct 1696 PSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 1734
Score = 35.1 bits (79), Expect = 1.6, Method: Composition-based stats.
Identities = 14/99 (14%), Positives = 28/99 (28%), Gaps = 0/99 (0%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGET 191
+ P P ++ P ++ + + EP + TP D T
Sbjct 1679 SDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPT 1738
Query 192 SDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
+ +P+ P P + + P P+
Sbjct 1739 PSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 1777
Score = 35.1 bits (79), Expect = 1.6, Method: Composition-based stats.
Identities = 14/99 (14%), Positives = 28/99 (28%), Gaps = 0/99 (0%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGET 191
+ P P ++ P ++ + + EP + TP D T
Sbjct 1722 SDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPT 1781
Query 192 SDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
+ +P+ P P + + P P+
Sbjct 1782 PSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 1820
Score = 35.1 bits (79), Expect = 1.6, Method: Composition-based stats.
Identities = 14/99 (14%), Positives = 28/99 (28%), Gaps = 0/99 (0%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGET 191
+ P P ++ P ++ + + EP + TP D T
Sbjct 1765 SDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPT 1824
Query 192 SDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
+ +P+ P P + + P P+
Sbjct 1825 PSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 1863
Score = 35.1 bits (79), Expect = 1.6, Method: Composition-based stats.
Identities = 14/99 (14%), Positives = 28/99 (28%), Gaps = 0/99 (0%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGET 191
+ P P ++ P ++ + + EP + TP D T
Sbjct 1808 SDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPT 1867
Query 192 SDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
+ +P+ P P + + P P+
Sbjct 1868 PSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 1906
Score = 35.1 bits (79), Expect = 1.6, Method: Composition-based stats.
Identities = 14/99 (14%), Positives = 28/99 (28%), Gaps = 0/99 (0%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGET 191
+ P P ++ P ++ + + EP + TP D T
Sbjct 1851 SDEPTPSDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPT 1910
Query 192 SDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
+ +P+ P P + + P P+
Sbjct 1911 PSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 1949
Score = 34.8 bits (78), Expect = 2.2, Method: Composition-based stats.
Identities = 18/98 (18%), Positives = 30/98 (31%), Gaps = 5/98 (5%)
Query 138 VLVPRHTEIPAEFPPLDDYSHSIPENTNFPA-GIEPQSNIPETPP----PGYLSEDGETS 192
V+ P + ++ P D P ++ P EP + TP P E+ +
Sbjct 1365 VIQPAPIKAASDEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPEEPIPT 1424
Query 193 DHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
D + + P S P +P P
Sbjct 1425 DTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSETPE 1462
Score = 33.6 bits (75), Expect = 4.1, Method: Composition-based stats.
Identities = 20/105 (19%), Positives = 33/105 (31%), Gaps = 6/105 (6%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYS-HSIPENTNFPAGIEPQSNIPETPPPGYLSEDGE 190
+ P P +E P E P D S P + P+ S+ P S++
Sbjct 1532 SDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPT 1591
Query 191 TSDHQMN-----HSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
SD + +P+ P P + + P P+
Sbjct 1592 PSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 1636
Score = 33.6 bits (75), Expect = 4.1, Method: Composition-based stats.
Identities = 20/105 (19%), Positives = 33/105 (31%), Gaps = 6/105 (6%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYS-HSIPENTNFPAGIEPQSNIPETPPPGYLSEDGE 190
+ P P +E P E P D S P + P+ S+ P S++
Sbjct 1587 SDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPT 1646
Query 191 TSDHQMN-----HSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
SD + +P+ P P + + P P+
Sbjct 1647 PSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 1691
Score = 33.6 bits (75), Expect = 4.1, Method: Composition-based stats.
Identities = 20/105 (19%), Positives = 33/105 (31%), Gaps = 6/105 (6%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYS-HSIPENTNFPAGIEPQSNIPETPPPGYLSEDGE 190
+ P P +E P E P D S P + P+ S+ P S++
Sbjct 1900 SDEPTPSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPTPSDEPT 1959
Query 191 TSDHQMN-----HSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
SD + +P+ P P + + P P+
Sbjct 1960 PSDEPTPSETPEEPIPTDTPSDEPTPSDEPTPSDEPTPSDEPTPS 2004
>sp|Q9HCD6|TANC2_HUMAN Protein TANC2 OS=Homo sapiens OX=9606 GN=TANC2
PE=1 SV=3
Length=1990
Score = 39.4 bits (90), Expect = 0.075, Method: Composition-based stats.
Identities = 31/159 (19%), Positives = 56/159 (35%), Gaps = 20/159 (13%)
Query 132 TPVLPPVLVPRHTEIP---AEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSED 188
TP P + EIP A D+ S P +P+ + TP G + +
Sbjct 1796 TPTFRPSSSIQQMEIPLKPAYERSCDELSPVSPTQGGYPS---EPTRSRTTPFMGIIDKT 1852
Query 189 GETSDHQMNHSMD-AGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGET 247
T + H + + + +SP QP ++ P+ +I++Y
Sbjct 1853 ARTQQYPHLHQQNRTWAVSSVDTVLSPTSPGNLPQPESFSPPSSISNIAFYNKTN----- 1907
Query 248 FHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELT 286
+A + D + P G+L+N +R +E
Sbjct 1908 -NAQNGHLLEDDYYSPH-------GMLANGSRGDLLERV 1938
>sp|P25623|SYP1_YEAST Suppressor of yeast profilin deletion OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=SYP1 PE=1 SV=3
Length=870
Score = 39.4 bits (90), Expect = 0.079, Method: Composition-based stats.
Identities = 28/111 (25%), Positives = 48/111 (43%), Gaps = 11/111 (10%)
Query 131 ETPVLPPVLVPRHTEIP--AEFPPLDDYSHSI-----PENTNFPAGIEP-QSNIPETPPP 182
+TP LPP P++ + P A+ PP ++ S P+ ++ P EP SN+P+T P
Sbjct 415 DTPPLPPHATPKNVDAPVTADTPPAQTFTPSEVPPSTPQQSSPPTAKEPDSSNLPKTVPI 474
Query 183 GYLSEDGETSDHQMNHSMDAGSPNLS-PNPMSPA--HNNLDLQPVTYCEPA 230
+ ++ SP++S P +D +P+ PA
Sbjct 475 SISQPPLQPQSKTKPLPVEPASPSISLPTATVDNQPSGQVDSRPLHIRAPA 525
>sp|G5EEL0|LIDB1_CAEEL LIM domain-binding protein 1 OS=Caenorhabditis
elegans OX=6239 GN=ldb-1 PE=1 SV=1
Length=592
Score = 39.0 bits (89), Expect = 0.091, Method: Composition-based stats.
Identities = 23/125 (18%), Positives = 38/125 (30%), Gaps = 11/125 (9%)
Query 111 FAFNMKKDEVCVNPYHY---QRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFP 167
+ + NP H +PP+ ++P P S+ +P + P
Sbjct 453 HSMGSQMPTSMHNPMHMPPGSMQGHGGMPPMPSTMANQMPPPNLPPHTMSNQMPNSRMPP 512
Query 168 AGIEPQSNIPETPPPGYLSEDGETS----DHQMNHSMDAGSPNLSPNPMSPAHNNLDLQP 223
Q +P + PG +S M+ M N PN M + P
Sbjct 513 M----QGQMPPSGMPGQMSNPNMMGSGMPPMSMSSQMPGSMSNPMPNQMPGGMQMNQMPP 568
Query 224 VTYCE 228
Y +
Sbjct 569 PNYSQ 573
>sp|Q9Y6V0|PCLO_HUMAN Protein piccolo OS=Homo sapiens OX=9606
GN=PCLO PE=1 SV=5
Length=5142
Score = 38.6 bits (88), Expect = 0.12, Method: Composition-based stats.
Identities = 17/110 (15%), Positives = 26/110 (24%), Gaps = 10/110 (9%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENT----NFPAGIEPQSNIPETPPPGYLSE 187
P PP +P + P + P P + P +P P P
Sbjct 465 GPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQP 524
Query 188 DGETSDHQMNHSMDAGSPNLSP------NPMSPAHNNLDLQPVTYCEPAF 231
Q S + SP P +P+ +
Sbjct 525 GSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSP 574
>sp|A2A690|TANC2_MOUSE Protein TANC2 OS=Mus musculus OX=10090
GN=Tanc2 PE=1 SV=1
Length=1994
Score = 38.6 bits (88), Expect = 0.13, Method: Composition-based stats.
Identities = 31/159 (19%), Positives = 56/159 (35%), Gaps = 20/159 (13%)
Query 132 TPVLPPVLVPRHTEIP---AEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSED 188
TP P + EIP A D+ S P +P+ + TP G + +
Sbjct 1800 TPTFRPSSSIQQMEIPLKPAYDRSCDELSPVSPTQGGYPS---EPTRSRTTPFMGIIDKT 1856
Query 189 GETSDHQMNHSMD-AGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGET 247
T + H + + + +SP QP ++ P+ +I++Y
Sbjct 1857 ARTQQYPHLHQQNRTWAVSSVDTVLSPTSPGNLPQPESFSPPSSISNIAFYNKTN----- 1911
Query 248 FHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELT 286
+A + D + P G+L+N +R +E
Sbjct 1912 -NAQNGHLLEDDYYSPH-------GMLANGSRGDLLERV 1942
>sp|Q63155|DCC_RAT Netrin receptor DCC OS=Rattus norvegicus OX=10116
GN=Dcc PE=1 SV=2
Length=1445
Score = 38.6 bits (88), Expect = 0.14, Method: Composition-based stats.
Identities = 18/94 (19%), Positives = 31/94 (33%), Gaps = 2/94 (2%)
Query 118 DEVCVNPYH-YQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNI 176
CV P H + P+LPP + ++P P L ++P+ A +
Sbjct 1330 PTACVRPTHPLRSFANPLLPPPMSAIEPKVPY-TPLLSQPGPTLPKTHVKTASLGLAGKA 1388
Query 177 PETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPN 210
P + E S+ + D S +
Sbjct 1389 RSPLLPVSVPTAPEVSEESHKPTEDPASVYEQDD 1422
>sp|P70211|DCC_MOUSE Netrin receptor DCC OS=Mus musculus OX=10090
GN=Dcc PE=1 SV=2
Length=1447
Score = 38.6 bits (88), Expect = 0.14, Method: Composition-based stats.
Identities = 18/94 (19%), Positives = 31/94 (33%), Gaps = 2/94 (2%)
Query 118 DEVCVNPYH-YQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNI 176
CV P H + P+LPP + ++P P L ++P+ A +
Sbjct 1332 PTACVRPTHPLRSFANPLLPPPMSAIEPKVPY-TPLLSQPGPTLPKTHVKTASLGLAGKA 1390
Query 177 PETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPN 210
P + E S+ + D S +
Sbjct 1391 RSPLLPVSVPTAPEVSEESHKPTEDPASVYEQDD 1424
>sp|Q9SZ15|LIP5_ARATH Protein HOMOLOG OF MAMMALIAN LYST-INTERACTING
PROTEIN 5 OS=Arabidopsis thaliana OX=3702 GN=LIP5 PE=1
SV=1
Length=421
Score = 37.8 bits (86), Expect = 0.19, Method: Composition-based stats.
Identities = 21/104 (20%), Positives = 33/104 (32%), Gaps = 8/104 (8%)
Query 136 PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFP--------AGIEPQSNIPETPPPGYLSE 187
P P H + P PP +YS P + P + S P P E
Sbjct 259 PYSHQPYHQDPPKHMPPPQNYSSHEPSPNSLPNFQSYPSFSESSLPSTSPHYPSHYQNPE 318
Query 188 DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
+S H + P P ++ +++ PV P+
Sbjct 319 PYYSSPHSAPAPSSTSFSSAPPPPPYSSNGRINIAPVLDPAPSS 362
>sp|Q8BI84|TGO1_MOUSE Transport and Golgi organization protein
1 homolog OS=Mus musculus OX=10090 GN=Mia3 PE=1 SV=2
Length=1930
Score = 37.8 bits (86), Expect = 0.25, Method: Composition-based stats.
Identities = 26/110 (24%), Positives = 37/110 (34%), Gaps = 15/110 (14%)
Query 125 YHYQRVETPVL---PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQ--SNIPET 179
Y Y VET L PP PP D S+P+ ++P + +
Sbjct 1011 YQYSGVETAPLVTPPPPEEGWARPGEERQPPQQD---SLPQENTGDLSVQPPEEPELSDQ 1067
Query 180 P-PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCE 228
P E+ E SD + P LS P++ +QP E
Sbjct 1068 PVTSVQPPEEPELSDQPVTSVQPPEEPELSDQPVTS------VQPPEEPE 1111
>sp|A1DLN3|SEC16_NEOFI COPII coat assembly protein sec16 OS=Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65
/ FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=sec16
PE=3 SV=1
Length=1835
Score = 37.5 bits (85), Expect = 0.26, Method: Composition-based stats.
Identities = 18/100 (18%), Positives = 30/100 (30%), Gaps = 2/100 (2%)
Query 134 VLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSD 193
+ P PR++ P + + + PA I Q + P
Sbjct 653 GVKPPPSPRYSPAPPQSTNAAAAAPPRNRYASQPASISGQGAALQFQPRTSSPLAYHEKI 712
Query 194 HQMNHSMDAGSPNLSPNPMSP--AHNNLDLQPVTYCEPAF 231
H + P L P + P H++ QPV+
Sbjct 713 HYQDQGQSEERPQLQPTAIPPPLNHSHPSEQPVSSENKGP 752
>sp|P9WHW5|PSTP_MYCTU Serine/threonine protein phosphatase PstP
OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
OX=83332 GN=pstP PE=1 SV=1
Length=514
Score = 37.5 bits (85), Expect = 0.27, Method: Composition-based stats.
Identities = 20/80 (25%), Positives = 27/80 (34%), Gaps = 2/80 (3%)
Query 135 LPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDH 194
LPP PR T P P + P T+ PA P ++ P P G ++
Sbjct 421 LPPCPAPRATSPPGRPAPPTTSETTEPNVTSSPASPSPTTSAPA--PTGTTPAIPTSASP 478
Query 195 QMNHSMDAGSPNLSPNPMSP 214
S P S M+
Sbjct 479 AAPASPPTPWPVTSSPTMAA 498
>sp|Q3UR85|MYRF_MOUSE Myelin regulatory factor OS=Mus musculus
OX=10090 GN=Myrf PE=1 SV=2
Length=1138
Score = 37.5 bits (85), Expect = 0.30, Method: Composition-based stats.
Identities = 34/178 (19%), Positives = 52/178 (29%), Gaps = 31/178 (17%)
Query 103 LRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSH---- 158
LRA++LC VC +P V +P P L P T P+
Sbjct 867 LRALDLCSS---QPCPIVCCSP----PVSSPATDPALGPTLTPTPSPSSNPKHSGPGQMA 919
Query 159 SIPENTNFPAGIEPQSN---------------IPETPPPGYLSEDGETSDHQMNHSMDAG 203
+P +N P P PG S+ + + G
Sbjct 920 PLPVTNIRAKSWGISANGISYSKHSKSLEPLASPVVPFPGGQSKTKNSPSFNLQSRARRG 979
Query 204 SPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFT 261
+P SP+P L P SI E + + + + + + FT
Sbjct 980 APQPSPSPAQFTQTQGQLDPAPSLT-----SIQLLENSMPITSQYCVPEGACRLGNFT 1032
>sp|O81765|PLRX4_ARATH Pollen-specific leucine-rich repeat extensin-like
protein 4 OS=Arabidopsis thaliana OX=3702 GN=PEX4
PE=2 SV=1
Length=699
Score = 37.1 bits (84), Expect = 0.32, Method: Composition-based stats.
Identities = 17/90 (19%), Positives = 23/90 (26%), Gaps = 3/90 (3%)
Query 130 VETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDG 189
V P P P H P P+ S P+ + P P +
Sbjct 425 VHKPT-PVPTTPVHKPTPVPTTPVQKPSPVPTTPVQKPSPVPTTPV--HEPSPVLATPVD 481
Query 190 ETSDHQMNHSMDAGSPNLSPNPMSPAHNNL 219
+ S P SP P P +
Sbjct 482 KPSPVPSRPVQKPQPPKESPQPDDPYDQSP 511
>sp|A1CZE5|INO80_NEOFI Chromatin-remodeling ATPase INO80 OS=Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65
/ FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=ino80
PE=3 SV=1
Length=1708
Score = 37.1 bits (84), Expect = 0.35, Method: Composition-based stats.
Identities = 18/91 (20%), Positives = 34/91 (37%), Gaps = 7/91 (8%)
Query 141 PRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSM 200
P + + P + P YS + +P + Q + P PP + + + +H
Sbjct 6 PYNPQSPTQQPRFPVYSPPNKNRSYYPNNDQYQQH-PPQTPPAFAPQPSLSRSPHYSH-- 62
Query 201 DAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
+P+ P + P N P + EP+
Sbjct 63 ---APSPLPATLPPL-NGGAPPPGHHSEPSS 89
>sp|P46593|HWP1_CANAL Hyphal wall protein 1 OS=Candida albicans
(strain SC5314 / ATCC MYA-2876) OX=237561 GN=HWP1 PE=1 SV=5
Length=634
Score = 37.1 bits (84), Expect = 0.37, Method: Composition-based stats.
Identities = 19/96 (20%), Positives = 30/96 (31%), Gaps = 2/96 (2%)
Query 137 PVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQM 196
P P+ + P ++P P+ P PQ ++P PP + + Q
Sbjct 83 PCDYPQQPQEPCDYPQQPQEPCDYPQQPQEPCDNPPQPDVPCDNPPQ--PDVPCDNPPQP 140
Query 197 NHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFW 232
+ D P P + D P P W
Sbjct 141 DVPCDNPPQPDVPCDNPPQPDQPDDNPPIPNIPTDW 176
>sp|Q8N6P7|I22R1_HUMAN Interleukin-22 receptor subunit alpha-1
OS=Homo sapiens OX=9606 GN=IL22RA1 PE=1 SV=1
Length=574
Score = 36.7 bits (83), Expect = 0.40, Method: Composition-based stats.
Identities = 23/117 (20%), Positives = 32/117 (27%), Gaps = 4/117 (3%)
Query 113 FNMKKDEVCVNPYHYQ--RVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGI 170
F++ P Y RV P P RH+ + D S P N P +
Sbjct 287 FDLSGPSSLAQPVQYSQIRVSGPREPAGAPQRHSLSEITYLGQPDISILQPSNVPPPQIL 346
Query 171 EPQSNIPETPPPGYLSE--DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVT 225
P S P P T + Q + P+ +P P
Sbjct 347 SPLSYAPNAAPEVGPPSYAPQVTPEAQFPFYAPQAISKVQPSSYAPQATPDSWPPSY 403
>sp|Q6PDK2|KMT2D_MOUSE Histone-lysine N-methyltransferase 2D OS=Mus
musculus OX=10090 GN=Kmt2d PE=1 SV=2
Length=5588
Score = 37.1 bits (84), Expect = 0.46, Method: Composition-based stats.
Identities = 19/104 (18%), Positives = 36/104 (35%), Gaps = 9/104 (9%)
Query 131 ETPVLPPVLVPRHT---EIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-IPETPPPGYLS 186
++P PP R + E PP +D S+P + + + + P+ P
Sbjct 669 DSPASPPPEASRLSRPREDSPASPPPEDSLVSLPMEESPLSPLPEELRLCPQPEEPYLSP 728
Query 187 EDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
+ E + LSP P + + ++P +P
Sbjct 729 QPEEPRLCPQPEELP-----LSPQSEEPCLSPVLVEPGPSSQPE 767
Score = 35.1 bits (79), Expect = 1.8, Method: Composition-based stats.
Identities = 21/98 (21%), Positives = 33/98 (34%), Gaps = 3/98 (3%)
Query 131 ETPVLPPVLVPRHTEIP---AEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSE 187
++P+ PP R + P PP +D S P + + S++ P LS
Sbjct 579 DSPLSPPPEASRLSPPPEDSPMSPPPEDSPMSPPPEVSRFLPLPVLSHLSPLPEVSRLSP 638
Query 188 DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVT 225
E S SP + +SP + P
Sbjct 639 PPEESPLSPPPEDSPASPPPEASRLSPPPEDSPASPPP 676
Score = 34.0 bits (76), Expect = 4.0, Method: Composition-based stats.
Identities = 25/104 (24%), Positives = 34/104 (33%), Gaps = 3/104 (3%)
Query 131 ETPVLPPVLVPRHTEIP--AEFPPLDDYSHSIPENTNFPAGIEPQ-SNIPETPPPGYLSE 187
E+P+ PP + P + P + S P + P P+ S P +LS
Sbjct 570 ESPLSPPPEDSPLSPPPEASRLSPPPEDSPMSPPPEDSPMSPPPEVSRFLPLPVLSHLSP 629
Query 188 DGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
E S SP +P SP L P PA
Sbjct 630 LPEVSRLSPPPEESPLSPPPEDSPASPPPEASRLSPPPEDSPAS 673
Score = 32.4 bits (72), Expect = 9.7, Method: Composition-based stats.
Identities = 24/111 (22%), Positives = 34/111 (31%), Gaps = 12/111 (11%)
Query 131 ETPVLPPVLVPRHTEIP--AEFPPLDDYSHSIP--------ENTNFPAGIEPQSNIPETP 180
++P+ PP + P + F PL SH P P + P +P
Sbjct 597 DSPMSPPPEDSPMSPPPEVSRFLPLPVLSHLSPLPEVSRLSPPPEESPLSPPPEDSPASP 656
Query 181 PP--GYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEP 229
PP LS E S S +P SP + + P
Sbjct 657 PPEASRLSPPPEDSPASPPPEASRLSRPREDSPASPPPEDSLVSLPMEESP 707
>sp|C4YHA6|HWP1_CANAW Hyphal wall protein 1 OS=Candida albicans
(strain WO-1) OX=294748 GN=HWP1 PE=3 SV=1
Length=633
Score = 36.7 bits (83), Expect = 0.47, Method: Composition-based stats.
Identities = 19/96 (20%), Positives = 30/96 (31%), Gaps = 2/96 (2%)
Query 137 PVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQM 196
P P+ + P ++P P+ P PQ ++P PP + + Q
Sbjct 83 PCDYPQQPQEPCDYPQQPQEPCDYPQQPQEPCDNPPQPDVPCDNPPQ--PDVPCDNPPQP 140
Query 197 NHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFW 232
+ D P P + D P P W
Sbjct 141 DIPCDNPPQPDIPCDNPPQPDQPDDNPPIPNIPTDW 176
>sp|Q2UCB7|MCA1B_ASPOR Metacaspase-1B OS=Aspergillus oryzae (strain
ATCC 42149 / RIB 40) OX=510516 GN=casB PE=3 SV=1
Length=419
Score = 36.3 bits (82), Expect = 0.50, Method: Composition-based stats.
Identities = 12/73 (16%), Positives = 23/73 (32%), Gaps = 1/73 (1%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYSH-SIPENTNFPAGIEPQSNIPETPPPGYLSEDGE 190
+ PP H+ P ++PP Y + +G + +S +P G +
Sbjct 42 SNGYPPPSQSPHSYSPPQYPPHGQYEYGHHTPTPPPSSGSQYRSYHSHSPSWGQMPPRPP 101
Query 191 TSDHQMNHSMDAG 203
Q +
Sbjct 102 MEAQQFGKGAPSN 114
>sp|Q9FZ35|PRP1_ARATH Proline-rich protein 1 OS=Arabidopsis thaliana
OX=3702 GN=PRP1 PE=2 SV=1
Length=335
Score = 36.3 bits (82), Expect = 0.52, Method: Composition-based stats.
Identities = 25/112 (22%), Positives = 34/112 (30%), Gaps = 5/112 (4%)
Query 124 PYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPG 183
P + V P LPP + P PP+ P P +P P PP
Sbjct 45 PVYTPPVHKPTLPPPVYTPPVHKPTLSPPVYTKPTLPPPAYTPPVYNKPTLPAPVYTPPV 104
Query 184 Y---LSEDGETSDHQMNHSMDA--GSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
Y LS T + P + +SP L P +P+
Sbjct 105 YKPTLSPPVYTKPTLLPPVFKPTLSPPVYTKPTLSPTVYKPTLSPPVNNKPS 156
Score = 33.6 bits (75), Expect = 3.7, Method: Composition-based stats.
Identities = 22/112 (20%), Positives = 35/112 (31%), Gaps = 6/112 (5%)
Query 117 KDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNI 176
V P H + PV +P P + P ++P P +P +
Sbjct 57 PPPVYTPPVHKPTLSPPVYTKPTLP-----PPAYTPPVYNKPTLPAPVYTPPVYKPTLSP 111
Query 177 PETPPPGYLSEDGETSDHQMNHSMDAGSPNL-SPNPMSPAHNNLDLQPVTYC 227
P P L + + ++ SP + P P +N L P Y
Sbjct 112 PVYTKPTLLPPVFKPTLSPPVYTKPTLSPTVYKPTLSPPVNNKPSLSPPVYK 163
Score = 32.8 bits (73), Expect = 6.1, Method: Composition-based stats.
Identities = 28/114 (25%), Positives = 37/114 (32%), Gaps = 10/114 (9%)
Query 124 PYHYQRVETPVLPPVLV--PRHT---EIPAEFPPLDDYSHSIPENTN----FPAGIEPQS 174
P + V P LPP + P H P PP+ + S P T PA P
Sbjct 31 PVYTSPVNKPTLPPPVYTPPVHKPTLPPPVYTPPVHKPTLSPPVYTKPTLPPPAYTPPVY 90
Query 175 NIPETPPPGYLSEDGETSDHQMNHSMDA-GSPNLSPNPMSPAHNNLDLQPVTYC 227
N P P P Y + + ++ P P P + L P Y
Sbjct 91 NKPTLPAPVYTPPVYKPTLSPPVYTKPTLLPPVFKPTLSPPVYTKPTLSPTVYK 144
Score = 32.4 bits (72), Expect = 7.3, Method: Composition-based stats.
Identities = 21/121 (17%), Positives = 35/121 (29%), Gaps = 15/121 (12%)
Query 124 PYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPG 183
P + V P L P + + T P + P ++P P +P + P P
Sbjct 59 PVYTPPVHKPTLSPPVYTKPTLPPPAYTPPVYNKPTLPAPVYTPPVYKPTLSPPVYTKPT 118
Query 184 YLSEDGETSDHQMNHSMDA---------------GSPNLSPNPMSPAHNNLDLQPVTYCE 228
L + + ++ P+LSP P + T
Sbjct 119 LLPPVFKPTLSPPVYTKPTLSPTVYKPTLSPPVNNKPSLSPPVYKPTLSPPVYTKPTLPP 178
Query 229 P 229
P
Sbjct 179 P 179
>sp|I1S4N7|BECN1_GIBZE Vacuolar protein sorting-associated protein
30 OS=Gibberella zeae (strain ATCC MYA-4620 / CBS 123657
/ FGSC 9075 / NRRL 31084 / PH-1) OX=229533 GN=VPS30 PE=3 SV=1
Length=487
Score = 36.3 bits (82), Expect = 0.53, Method: Composition-based stats.
Identities = 20/110 (18%), Positives = 32/110 (29%), Gaps = 0/110 (0%)
Query 109 CEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPA 168
C + +NP Y + P L P P D SI + + A
Sbjct 6 CRQPLRLDGSLEDLNPAAYDVLVASASPQTLKKSSVPNPPLAQPQDQSRKSIYDRVSRNA 65
Query 169 GIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNN 218
G + P S+ QM + P +P + A ++
Sbjct 66 GPPTFKRNHGSHPRDSSMSFVLLSESQMARPTPSSDPPTTPTVLRRASSS 115
>sp|Q9CXK9|RBM33_MOUSE RNA-binding protein 33 OS=Mus musculus
OX=10090 GN=Rbm33 PE=1 SV=2
Length=1231
Score = 36.7 bits (83), Expect = 0.54, Method: Composition-based stats.
Identities = 27/129 (21%), Positives = 43/129 (33%), Gaps = 15/129 (12%)
Query 118 DEVCVNPYHYQRVETPV----LPPVLVPRHTEIPAEFPPLDDYSHS----IPENTNFPAG 169
+ +NP+ V TPV LP PR P FP ++ +P + N P
Sbjct 433 KNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFNQPPR 492
Query 170 IEPQSNIPETPPPG-------YLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQ 222
+ Q PPP +S + H P P ++ +H
Sbjct 493 LPLQDQWRAPPPPQERDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQS 552
Query 223 PVTYCEPAF 231
P+ + +P
Sbjct 553 PLPFTQPGP 561
>sp|P43146|DCC_HUMAN Netrin receptor DCC OS=Homo sapiens OX=9606
GN=DCC PE=1 SV=2
Length=1447
Score = 36.7 bits (83), Expect = 0.55, Method: Composition-based stats.
Identities = 17/94 (18%), Positives = 32/94 (34%), Gaps = 2/94 (2%)
Query 118 DEVCVNPYH-YQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNI 176
CV P H + P+LPP + ++P P L ++P+ A +
Sbjct 1332 PTACVRPTHPLRSFANPLLPPPMSAIEPKVPY-TPLLSQPGPTLPKTHVKTASLGLAGKA 1390
Query 177 PETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPN 210
P + E S+ + D+ + +
Sbjct 1391 RSPLLPVSVPTAPEVSEESHKPTEDSANVYEQDD 1424
>sp|Q8L611|SC31B_ARATH Protein transport protein SEC31 homolog
B OS=Arabidopsis thaliana OX=3702 GN=SEC31B PE=1 SV=1
Length=1104
Score = 36.7 bits (83), Expect = 0.56, Method: Composition-based stats.
Identities = 25/126 (20%), Positives = 37/126 (29%), Gaps = 16/126 (13%)
Query 117 KDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNI 176
+ V NPY + + P VP+ + P + P + + + P P
Sbjct 812 QPNVLANPYD-NQYQQPYTDSYYVPQVSHPPMQQPTM--FMPHQAQPAPQP-SFTPAPTS 867
Query 177 PETP----------PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHN--NLDLQPV 224
P PP + D +HS S N P P P + Q
Sbjct 868 NAQPSMRTTFVPSTPPALKNADQYQQPTMSSHSFTGPSNNAYPVPPGPGQYAPSGPSQLG 927
Query 225 TYCEPA 230
Y P
Sbjct 928 QYPNPK 933
>sp|P0CAQ1|UBP16_EMENI Ubiquitin carboxyl-terminal hydrolase 16
OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS
112.46 / NRRL 194 / M139) OX=227321 GN=ubp16 PE=3 SV=1
Length=624
Score = 36.3 bits (82), Expect = 0.61, Method: Composition-based stats.
Identities = 28/126 (22%), Positives = 43/126 (34%), Gaps = 10/126 (8%)
Query 111 FAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGI 170
F+ + NP RV +P LP + PP + S +TN P +
Sbjct 443 FSSYAQSRAASENP---SRVASPRLP-------ASSSSTEPPALNISPPASTSTNSPLSL 492
Query 171 EPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
P S S TS +++ S + +P S A N+ L PA
Sbjct 493 TPDSPSRPPSATDLKSPRPTTSSSRVSFQSTHSSSKQTISPTSAARNSSSLDTARLSSPA 552
Query 231 FWCSIS 236
S++
Sbjct 553 SRSSLA 558
>sp|A2R4T4|SEC16_ASPNC COPII coat assembly protein sec16 OS=Aspergillus
niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513)
OX=425011 GN=sec16 PE=3 SV=2
Length=1914
Score = 36.3 bits (82), Expect = 0.63, Method: Composition-based stats.
Identities = 26/123 (21%), Positives = 40/123 (33%), Gaps = 19/123 (15%)
Query 125 YHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYS----------------HSIPENTNFPA 168
YH + P P P E PA PP++ S +PE N +
Sbjct 792 YHEKVSYRPQEPSEQQPSAMEQPAIIPPIEVQSQPTAPAEYSPIQPPEVPHVPEAVNMGS 851
Query 169 GIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCE 228
+ S P +PP + G + + A P P P+ PA + + P
Sbjct 852 SVHQMSQQPMSPPRNQYAPPGYVDEFSKRIAPIANVP---PAPVLPADDPTFVPPRRSMT 908
Query 229 PAF 231
+
Sbjct 909 QSP 911
>sp|Q61329|ZFHX3_MOUSE Zinc finger homeobox protein 3 OS=Mus musculus
OX=10090 GN=Zfhx3 PE=1 SV=1
Length=3726
Score = 36.3 bits (82), Expect = 0.71, Method: Composition-based stats.
Identities = 22/106 (21%), Positives = 26/106 (25%), Gaps = 0/106 (0%)
Query 106 MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTN 165
ME C+ KD C P H Q E P E P S P N
Sbjct 1 MEGCDSPVVSGKDNGCGIPQHRQWTELNSAHLPDKPSSMEQPTGESHGPLDSLRAPFNER 60
Query 166 FPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNP 211
E + S + M+ P P P
Sbjct 61 LADSSTSAGPPAEPASKEVSCNECSASFSSLQTYMEHHCPGTHPPP 106
>sp|P29674|LHX1_XENLA LIM/homeobox protein Lhx1 OS=Xenopus laevis
OX=8355 GN=lhx1 PE=1 SV=1
Length=403
Score = 35.5 bits (80), Expect = 0.83, Method: Composition-based stats.
Identities = 21/98 (21%), Positives = 29/98 (30%), Gaps = 1/98 (1%)
Query 136 PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGET-SDH 194
PV +P PL H IP + + P E S H
Sbjct 306 TPVDLPFVPSSVPAGTPLGAMDHPIPGHHPSSDAQRFTDIMSHPPGDSPSPEPNLPGSMH 365
Query 195 QMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFW 232
M+ + SP S ++ + N P E A W
Sbjct 366 SMSAEVFGQSPPFSSLSVNGGYGNHLSHPPEMNETAVW 403
>sp|Q67724|RDRP_HASV Methyltransferase/helicase/RNA-directed RNA
polymerase OS=Helicoverpa armigera stunt virus OX=37206 PE=2
SV=1
Length=1704
Score = 35.9 bits (81), Expect = 0.92, Method: Composition-based stats.
Identities = 27/153 (18%), Positives = 44/153 (29%), Gaps = 12/153 (8%)
Query 94 WPDLHSHHELRAMELCEFAFNMKKDEVCVNP-YHYQRVETPVLPPVLVPRHTEIP--AEF 150
W D H L M C + + + ++ + R + P +V H + P
Sbjct 1306 WSDARYHSLLCHMSACYYNYAPESAAYIIDAVVRFGRGDFPFEQLRVVRAHVQAPDAYSS 1365
Query 151 PPLDDYSHS------IPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGS 204
+ S P PAG PETP +H +
Sbjct 1366 TYPANVRASCLDHVFEPRQAAAPAGFVATCAKPETPSSLTAKAGVS---ATTSHVATGTA 1422
Query 205 PNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISY 237
P SP A++ +L + I +
Sbjct 1423 PPESPWDAPAANSFSELLTPETPSTSSSAVIVF 1455
>sp|Q16U49|MED14_AEDAE Mediator of RNA polymerase II transcription
subunit 14 OS=Aedes aegypti OX=7159 GN=MED14 PE=3 SV=2
Length=1578
Score = 35.9 bits (81), Expect = 0.97, Method: Composition-based stats.
Identities = 16/104 (15%), Positives = 25/104 (24%), Gaps = 7/104 (7%)
Query 129 RVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSED 188
R P+ PP HT + NF P ++P P G L
Sbjct 1057 RFAAPLTPPSGSNPHTPASPHPQGIGGSQSH----PNFNMTSPPAPHMPHPSPSGGLMPS 1112
Query 189 GETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFW 232
+ + + P P + + W
Sbjct 1113 SPLNPQPSPMAAHSPGPTNLPYMSGHTDSPFSAHSPAA---SNW 1153
>sp|Q96EV2|RBM33_HUMAN RNA-binding protein 33 OS=Homo sapiens
OX=9606 GN=RBM33 PE=1 SV=3
Length=1170
Score = 35.5 bits (80), Expect = 1.2, Method: Composition-based stats.
Identities = 26/129 (20%), Positives = 43/129 (33%), Gaps = 15/129 (12%)
Query 118 DEVCVNPYHYQRVETPV----LPPVLVPRHTEIPAEFPPLDDYSHS----IPENTNFPAG 169
+ +NP+ V TPV LP PR P FP ++ +P + + P
Sbjct 383 KNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPR 442
Query 170 IEPQSNIPETPPPG-------YLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQ 222
+ Q PPP +S + H P P ++ +H
Sbjct 443 LPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQS 502
Query 223 PVTYCEPAF 231
P+ + +P
Sbjct 503 PLPFTQPGP 511
>sp|Q7RTP6|MICA3_HUMAN [F-actin]-monooxygenase MICAL3 OS=Homo
sapiens OX=9606 GN=MICAL3 PE=1 SV=2
Length=2002
Score = 35.5 bits (80), Expect = 1.2, Method: Composition-based stats.
Identities = 21/110 (19%), Positives = 32/110 (29%), Gaps = 4/110 (4%)
Query 124 PYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIE----PQSNIPET 179
P H E P LPPV + P E + + P+ ++ P + P T
Sbjct 1170 PVHSPSTEGPQLPPVPAATQEKSPEERLFPEPLLPKEKPKADAPSDLKAVHSPIRSQPVT 1229
Query 180 PPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEP 229
P + Q + P+ P P + P P
Sbjct 1230 LPEARTPVSPGSPQPQPPVAASTPPPSPLPICSQPQPSTEATVPSPTQSP 1279
>sp|Q640P2|ANGL1_MOUSE Angiopoietin-related protein 1 OS=Mus musculus
OX=10090 GN=Angptl1 PE=2 SV=1
Length=490
Score = 35.1 bits (79), Expect = 1.3, Method: Composition-based stats.
Identities = 22/118 (19%), Positives = 44/118 (37%), Gaps = 9/118 (8%)
Query 127 YQRVETPVLPPVL--VPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGY 184
+ R + PP++ VPRH+ ++ P + I + +P + P ++P P
Sbjct 203 FSRQDPHASPPLVQVVPRHSPNSHQYTPGLLGGNEIQRDPGYPRDVMPPPDLPTAPTKSP 262
Query 185 LSEDGETSDHQMN-----HSMDAGSPNLSPNPMSPAHNNLDLQPVTYC--EPAFWCSI 235
T ++ + +AG + P ++N +Q +P W I
Sbjct 263 FKIPAVTFINEGPFKDCQQAKEAGHSASGIYMIKPENSNGLMQLWCENSLDPGGWTVI 320
>sp|Q9HCU0|CD248_HUMAN Endosialin OS=Homo sapiens OX=9606 GN=CD248
PE=1 SV=1
Length=757
Score = 35.1 bits (79), Expect = 1.3, Method: Composition-based stats.
Identities = 21/108 (19%), Positives = 36/108 (33%), Gaps = 8/108 (7%)
Query 131 ETPVLPPVLVPRHTEIPAEFPP-------LDDYSHSIPENTNFPAGIEPQSNIPETPPPG 183
P +PP P T + A+ PP L + +P + S P P
Sbjct 546 HLPGIPPNHAPLVTTLGAQLPPQAPDALVLRTQATQLPIIPTAQPSLTTTSRSP-VSPAH 604
Query 184 YLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
+S T + + + SP +P+SP H + + +
Sbjct 605 QISVPAATQPAALPTLLPSQSPTNQTSPISPTHPHSKAPQIPREDGPS 652
>sp|P9WHW4|PSTP_MYCTO Serine/threonine protein phosphatase PstP
OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
OX=83331 GN=pstP PE=3 SV=1
Length=514
Score = 35.1 bits (79), Expect = 1.3, Method: Composition-based stats.
Identities = 19/80 (24%), Positives = 25/80 (31%), Gaps = 2/80 (3%)
Query 135 LPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDH 194
LPP PR T P P + P T+ PA P + P G ++
Sbjct 421 LPPCPAPRATSPPGRPAPPTTSETTEPNVTSSPAS--PSPTTSASAPTGTTPAIPTSASP 478
Query 195 QMNHSMDAGSPNLSPNPMSP 214
S P S M+
Sbjct 479 AAPASPPTPWPVTSSPTMAA 498
>sp|Q6AXT8|SF3A2_RAT Splicing factor 3A subunit 2 OS=Rattus norvegicus
OX=10116 GN=Sf3a2 PE=2 SV=1
Length=471
Score = 35.1 bits (79), Expect = 1.3, Method: Composition-based stats.
Identities = 20/94 (21%), Positives = 29/94 (31%), Gaps = 2/94 (2%)
Query 133 PVLPPVLVPRHTEIPAEFPP-LDDYSHSIPENTNFPAGIEPQSNIPETPPPG-YLSEDGE 190
P + P H P PP + + + AG+ PQ+ P P + G
Sbjct 348 PGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQAPGV 407
Query 191 TSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPV 224
H G P + PA + QP
Sbjct 408 HPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPP 441
>sp|Q1HVG4|EBNA4_EBVA8 Epstein-Barr nuclear antigen 4 OS=Epstein-Barr
virus (strain AG876) OX=82830 GN=EBNA4 PE=3 SV=2
Length=946
Score = 35.1 bits (79), Expect = 1.4, Method: Composition-based stats.
Identities = 20/96 (21%), Positives = 28/96 (29%), Gaps = 3/96 (3%)
Query 135 LPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDH 194
LP + P P S P + P + S P P L+ + E
Sbjct 564 LPAPGLGPLAIQPLTSPTTSQLRSSAPSHAQTPWPVTHPSQTPGGPTTQSLAPETE---A 620
Query 195 QMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
M L P M P N ++P + P
Sbjct 621 PRQWPMPLRPIPLHPLRMQPISFNPAVRPTPHQPPQ 656
>sp|Q32L53|LFG1_BOVIN Protein lifeguard 1 OS=Bos taurus OX=9913
GN=GRINA PE=2 SV=1
Length=366
Score = 34.8 bits (78), Expect = 1.4, Method: Composition-based stats.
Identities = 15/86 (17%), Positives = 19/86 (22%), Gaps = 0/86 (0%)
Query 146 IPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSP 205
P P + P P+ PPG + G
Sbjct 35 APYPQAPFQPSPYGQPGYPQGPSPYPQGGYPQGPYPPGGYPQGPYPPGGYPQGPYPPGGY 94
Query 206 NLSPNPMSPAHNNLDLQPVTYCEPAF 231
P P SP N QP +
Sbjct 95 PQGPYPQSPFPPNPYGQPQAFPAQDP 120
>sp|Q91924|SNAI2_XENLA Zinc finger protein SNAI2 OS=Xenopus laevis
OX=8355 GN=snai2 PE=1 SV=1
Length=266
Score = 34.4 bits (77), Expect = 1.5, Method: Composition-based stats.
Identities = 38/236 (16%), Positives = 71/236 (30%), Gaps = 23/236 (10%)
Query 112 AFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIE 171
+ V ++P+ Y+R VLP + +P + + P
Sbjct 19 YGELDNHTVIISPFLYERYPVSVLPQPDIYSSVAYSPITVWTGLLHPPLPSDLS-PLSGY 77
Query 172 PQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
P S +PPP D + DH + S + +S +H F
Sbjct 78 PSSLGRVSPPPQ---SDTSSKDHSGSESPISDEEERLQTKLSDSH--------AIEAEKF 126
Query 232 WCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFC------LGLLSNVNRNAAVEL 285
CS+ + G A + D + S S ++C LG L R +
Sbjct 127 QCSLCSKTYSTFSG---LAKHKQLHCDAQSRKSFSCKYCEKEYVSLGALKMHIRTHTLPC 183
Query 286 TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLK 341
+ G+ ++ + P+CN+ + + ++K
Sbjct 184 VCKICGKAFSRPWLLQGHIRTHTGEKPF--SCPHCNRAFADRSNLRAHLQTHSDVK 237
>sp|Q7SAN9|BRO1_NEUCR Vacuolar protein-sorting protein bro-1 OS=Neurospora
crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71
/ DSM 1257 / FGSC 987) OX=367110 GN=bro-1 PE=3 SV=1
Length=1012
Score = 34.8 bits (78), Expect = 1.8, Method: Composition-based stats.
Identities = 18/91 (20%), Positives = 25/91 (27%), Gaps = 4/91 (4%)
Query 141 PRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSM 200
R T P F P + P + + Q P +PP + +
Sbjct 801 GRPTPAPLSFAPAA--VSNTPLSAYQKSNFSTQ--YPASPPATQVPHNPGGQQQTPYQQY 856
Query 201 DAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
+ S P P SP N PA
Sbjct 857 NPSSLGRIPGPASPPPNQTSFNIGPGRHPAS 887
Score = 33.6 bits (75), Expect = 4.3, Method: Composition-based stats.
Identities = 13/80 (16%), Positives = 22/80 (28%), Gaps = 0/80 (0%)
Query 133 PVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETS 192
P PP H + P Y+ S PA P P + + T
Sbjct 833 PASPPATQVPHNPGGQQQTPYQQYNPSSLGRIPGPASPPPNQTSFNIGPGRHPASPPPTQ 892
Query 193 DHQMNHSMDAGSPNLSPNPM 212
+ + +P+ +
Sbjct 893 TSFAQSRPYSLTTYGNPSAL 912
>sp|Q64289|NDF1_RAT Neurogenic differentiation factor 1 OS=Rattus
norvegicus OX=10116 GN=Neurod1 PE=1 SV=1
Length=357
Score = 34.4 bits (77), Expect = 1.8, Method: Composition-based stats.
Identities = 23/132 (17%), Positives = 40/132 (30%), Gaps = 7/132 (5%)
Query 122 VNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPE--T 179
+NP + + P +PP H + P+ YS+ P + P G S++
Sbjct 190 LNPRTFLPEQNPDMPP-----HLPTASASFPVHPYSYQSPGLPSPPYGTMDSSHVFHVKP 244
Query 180 PPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYE 239
PP Y + + + P+S N + + +Y
Sbjct 245 PPHAYSAALEPFFESPLTDCTSPSFDGPLSPPLSINGNFSFKHEPSTEFEKNYAFTMHYP 304
Query 240 LNQRVGETFHAS 251
G H S
Sbjct 305 AATLAGPQSHGS 316
>sp|Q60867|NDF1_MOUSE Neurogenic differentiation factor 1 OS=Mus
musculus OX=10090 GN=Neurod1 PE=1 SV=2
Length=357
Score = 34.4 bits (77), Expect = 1.8, Method: Composition-based stats.
Identities = 23/132 (17%), Positives = 40/132 (30%), Gaps = 7/132 (5%)
Query 122 VNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPE--T 179
+NP + + P +PP H + P+ YS+ P + P G S++
Sbjct 190 LNPRTFLPEQNPDMPP-----HLPTASASFPVHPYSYQSPGLPSPPYGTMDSSHVFHVKP 244
Query 180 PPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYE 239
PP Y + + + P+S N + + +Y
Sbjct 245 PPHAYSAALEPFFESPLTDCTSPSFDGPLSPPLSINGNFSFKHEPSAEFEKNYAFTMHYP 304
Query 240 LNQRVGETFHAS 251
G H S
Sbjct 305 AATLAGPQSHGS 316
>sp|Q5XJ13|ANKS6_DANRE Ankyrin repeat and SAM domain-containing
protein 6 OS=Danio rerio OX=7955 GN=anks6 PE=2 SV=1
Length=739
Score = 34.8 bits (78), Expect = 1.8, Method: Composition-based stats.
Identities = 15/91 (16%), Positives = 27/91 (30%), Gaps = 0/91 (0%)
Query 139 LVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNH 198
P HT +P P L+ N++ P +P P + T H+
Sbjct 557 PSPAHTPLPDSRPKLELQKRPQSGNSSRSKSTSPTLTPSPSPTPAHTPAPAHTPAHRPTG 616
Query 199 SMDAGSPNLSPNPMSPAHNNLDLQPVTYCEP 229
+ + S S + +T +
Sbjct 617 ASADSQGSASTQQRSRSSGGSSSGTITDEDE 647
>sp|Q9LYW5|LUL1_ARATH Probable E3 ubiquitin-protein ligase LUL1
OS=Arabidopsis thaliana OX=3702 GN=LUL1 PE=1 SV=1
Length=337
Score = 34.4 bits (77), Expect = 1.9, Method: Composition-based stats.
Identities = 24/105 (23%), Positives = 38/105 (36%), Gaps = 6/105 (6%)
Query 110 EFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAG 169
F F + NP + + LPP + TE P + H P + P
Sbjct 34 RFVFAAVPPYLNPNPNYVDQYPGNCLPPPV----TEPPMLPYNFNHLHHYPPNSYQLPHP 89
Query 170 IEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSP 214
+ P PPP Y+ + T + +N + L P+P +P
Sbjct 90 LFHGGRYPILPPPTYVHQKAVTIRNDVNLKKKTLT--LIPDPENP 132
>sp|Q62203|SF3A2_MOUSE Splicing factor 3A subunit 2 OS=Mus musculus
OX=10090 GN=Sf3a2 PE=1 SV=2
Length=475
Score = 34.8 bits (78), Expect = 1.9, Method: Composition-based stats.
Identities = 20/94 (21%), Positives = 29/94 (31%), Gaps = 2/94 (2%)
Query 133 PVLPPVLVPRHTEIPAEFPP-LDDYSHSIPENTNFPAGIEPQSNIPETPPPG-YLSEDGE 190
P + P H P PP + + + AG+ PQ+ P P + G
Sbjct 345 PGVHPPTPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPPAPAVHPQAPGV 404
Query 191 TSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPV 224
H G P + PA + QP
Sbjct 405 HPPAPGIHPQAPGVHPQPPPGVHPAAPGVHPQPP 438
>sp|Q96NZ1|FOXN4_HUMAN Forkhead box protein N4 OS=Homo sapiens
OX=9606 GN=FOXN4 PE=1 SV=2
Length=517
Score = 34.4 bits (77), Expect = 2.2, Method: Composition-based stats.
Identities = 35/187 (19%), Positives = 63/187 (34%), Gaps = 21/187 (11%)
Query 137 PVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETP-------PPGYLSEDG 189
P+L P P L + + FP G +P S + + P P + G
Sbjct 94 PLLHGPAGMAPRGMPGLGPITGHRDSMSQFPVGGQPSSGLQDPPHLYSPATQPQFPLPPG 153
Query 190 ETSDHQMN-HSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEP--AFWCSISYYELNQRVGE 246
+ + G P P H++ +L P Y +P ++ C I+ N + G
Sbjct 154 AQQCPPVGLYGPPFGVRPPYPQPHVAVHSSQELHPKHYPKPIYSYSCLIAMALKNSKTGS 213
Query 247 TFHASQPSMTVDGF----TDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGE 302
+ S + F T P G ++V N ++ + + G
Sbjct 214 LPVSEIYSFMKEHFPYFKTAPD-------GWKNSVRHNLSLNKCFEKVENKMSGSSRKGC 266
Query 303 VFAECLS 309
++A L+
Sbjct 267 LWALNLA 273
>sp|P53236|RSC1_YEAST Chromatin structure-remodeling complex subunit
RSC1 OS=Saccharomyces cerevisiae (strain ATCC 204508
/ S288c) OX=559292 GN=RSC1 PE=1 SV=1
Length=928
Score = 34.4 bits (77), Expect = 2.3, Method: Composition-based stats.
Identities = 30/148 (20%), Positives = 50/148 (34%), Gaps = 18/148 (12%)
Query 65 ITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNP 124
I + + G++ + RK P V Y L R P++ FA +M+ ++ NP
Sbjct 99 ILLESFIKGKIVHNIRKHYPEVTYPSLGRIPEI-------------FAESMQPSDLSSNP 145
Query 125 YHYQRVE-----TPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPET 179
+ Q + P + + I P DY + FP + P
Sbjct 146 INTQENDEKAGLNPEMKMAFAKLDSSITERKPTNQDYRMQQKNSPAFPTHSASITPQPLA 205
Query 180 PPPGYLSEDGETSDHQMNHSMDAGSPNL 207
P ++ TS H H P +
Sbjct 206 SPTPVVNYANITSAHPKTHVRRGRPPVI 233
>sp|O60130|YH7G_SCHPO Putative transcriptional regulatory protein
C16G5.16 OS=Schizosaccharomyces pombe (strain 972 / ATCC
24843) OX=284812 GN=SPBC16G5.16 PE=1 SV=1
Length=827
Score = 34.4 bits (77), Expect = 2.4, Method: Composition-based stats.
Identities = 16/70 (23%), Positives = 22/70 (31%), Gaps = 0/70 (0%)
Query 143 HTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDA 202
+T P FP Y + +N P + S P PP LSE
Sbjct 723 NTYSPVPFPYNTSYPPYMSPTSNMPQAFQAYSQYPYQHPPFPLSEQMLPLPTSGVMMAPG 782
Query 203 GSPNLSPNPM 212
+ + P P
Sbjct 783 AAKSGMPYPF 792
>sp|Q9NQW1|SC31B_HUMAN Protein transport protein Sec31B OS=Homo
sapiens OX=9606 GN=SEC31B PE=1 SV=1
Length=1179
Score = 34.4 bits (77), Expect = 2.4, Method: Composition-based stats.
Identities = 23/114 (20%), Positives = 33/114 (29%), Gaps = 12/114 (11%)
Query 130 VETPVLPPVLVPR-------HTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSN-----IP 177
V PP PR H++ + + SH +P + P PQS+ P
Sbjct 788 VLGQQSPPFPFPRIVVGATLHSKETSSYRLGSQPSHQVPTPSPRPRVFTPQSSPAMPLAP 847
Query 178 ETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
P P SD++ LSP + L P
Sbjct 848 SHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRPASSQPQLLGGQRVQVPNP 901
>sp|Q9CXC9|ETV5_MOUSE ETS translocation variant 5 OS=Mus musculus
OX=10090 GN=Etv5 PE=2 SV=1
Length=510
Score = 34.0 bits (76), Expect = 2.9, Method: Composition-based stats.
Identities = 19/102 (19%), Positives = 22/102 (22%), Gaps = 8/102 (8%)
Query 136 PPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIP-----ETPPPGYLSEDG- 189
PP T P S P P P P P L E G
Sbjct 127 PPSGFKPLTPPATPLSPTHQNSLFPPPQATLPTSGLTPGAGPVQGVGPAPTPHSLPEPGS 186
Query 190 --ETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEP 229
+T P + P P+ Q P
Sbjct 187 QQQTFAVPRPPHQPLQMPKMMPESQYPSEQRFQRQLSEPSHP 228
>sp|Q5PT56|NTCP4_RAT Sodium/bile acid cotransporter 4 OS=Rattus
norvegicus OX=10116 GN=Slc10a4 PE=1 SV=1
Length=437
Score = 33.6 bits (75), Expect = 3.3, Method: Composition-based stats.
Identities = 22/118 (19%), Positives = 38/118 (32%), Gaps = 3/118 (3%)
Query 144 TEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGY-LSEDGETSDHQMNHSMDA 202
T + A L D P ++ A + +P PG L+
Sbjct 8 TRLLAPSSLLPDNLTLSPNASSTSASTLSPLPVTSSPSPGLSLAPTPSIGFSPDLTPTPE 67
Query 203 GSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHAS--QPSMTVD 258
+ + ++ ++ +P EP FW + + LN VG + TVD
Sbjct 68 PTSSSLAGGVAGQDSSTFPRPWIPHEPPFWDTPLNHGLNVFVGAALCITMLGLGCTVD 125
>sp|O42854|YFHH_SCHPO SH3 domain-containing protein C23A1.17 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=SPAC23A1.17 PE=1 SV=1
Length=1611
Score = 34.0 bits (76), Expect = 3.7, Method: Composition-based stats.
Identities = 18/96 (19%), Positives = 27/96 (28%), Gaps = 3/96 (3%)
Query 134 VLPPVLVPRHTEI-PAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETS 192
PPV +P T P +P ++ I S P P P + + S
Sbjct 1039 TAPPVPIPTSTPPVPKSSSGAPSAPPPVPAPSSEIPSIPAPSGAPPVPAPSGIPPVPKPS 1098
Query 193 DH--QMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTY 226
+ A P +P+ P P
Sbjct 1099 VAAPPVPKPSVAVPPVPAPSGAPPVPKPSVAAPPVP 1134
Score = 33.2 bits (74), Expect = 5.9, Method: Composition-based stats.
Identities = 16/100 (16%), Positives = 31/100 (31%), Gaps = 6/100 (6%)
Query 131 ETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGE 190
E P +P P+ PP+ S + P +P +P P P +
Sbjct 1072 EIPSIPAPSGAPPVPAPSGIPPVPKPSVAAPPVP------KPSVAVPPVPAPSGAPPVPK 1125
Query 191 TSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPA 230
S + +G+P + ++ +P+
Sbjct 1126 PSVAAPPVPVPSGAPPVPKPSVAAPPVPAPSGAPPVPKPS 1165
>sp|Q921L5|COG2_MOUSE Conserved oligomeric Golgi complex subunit
2 OS=Mus musculus OX=10090 GN=Cog2 PE=1 SV=2
Length=731
Score = 33.6 bits (75), Expect = 3.8, Method: Composition-based stats.
Identities = 16/91 (18%), Positives = 26/91 (29%), Gaps = 3/91 (3%)
Query 181 PPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYEL 240
P + D + + SMD + L P + W Y+++
Sbjct 329 PSLFNPGDPDAFHQKYTVSMDFVQRFERQCGSQASVKRLRAHPAYHNFSNKWNLPVYFQI 388
Query 241 NQRVGETFHASQPSMTVDGFTDPSNSERFCL 271
R S + DG D +CL
Sbjct 389 RFR---EVAGSLEAALTDGLEDAPAGSPYCL 416
>sp|P83093|STIM2_MOUSE Stromal interaction molecule 2 OS=Mus musculus
OX=10090 GN=Stim2 PE=1 SV=2
Length=746
Score = 33.6 bits (75), Expect = 3.9, Method: Composition-based stats.
Identities = 19/130 (15%), Positives = 38/130 (29%), Gaps = 10/130 (8%)
Query 76 QVSHRKGLPHVIYC---RLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYH-YQRVE 131
+ +K L + C RL+RW ++ + + A N + + Y + V
Sbjct 413 ILEAKKALSELTTCLRERLFRW------QQIEKICGFQIAHNSGLPSLTSSLYSDHSWVV 466
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGET 191
P + P + P PAG +S+ + ++
Sbjct 467 MPRVSIPPYPIAGGVDDLDEDTPPIVPQFPGTVAKPAGSLARSSSLCRSRRSIVPSSPQS 526
Query 192 SDHQMNHSMD 201
Q+
Sbjct 527 QRAQLPAHAP 536
>sp|O13637|SEC31_SCHPO Protein transport protein sec31 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=sec31
PE=1 SV=1
Length=1224
Score = 33.6 bits (75), Expect = 4.1, Method: Composition-based stats.
Identities = 19/103 (18%), Positives = 30/103 (29%), Gaps = 9/103 (9%)
Query 125 YHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGY 184
YH +PPV P H Y+ P++ A S P
Sbjct 935 YHPPTASGTRVPPVQQPSHPNP---------YTPVAPQSPVAAASRISSSPNMPPSNPYT 985
Query 185 LSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYC 227
++ + + G + P P PA+ + L P
Sbjct 986 PIAVASSTVNPAHTYKPHGGSQIVPPPKQPANRVVPLPPTASQ 1028
Score = 32.8 bits (73), Expect = 8.3, Method: Composition-based stats.
Identities = 21/114 (18%), Positives = 36/114 (32%), Gaps = 9/114 (8%)
Query 110 EFAFNMKKDEVCV-NPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPA 168
+ A + V V +P TP LPPV + PP+ IP+
Sbjct 1028 QRASAYEPPTVSVPSPSALSPSVTPQLPPV--------SSRLPPVSATRPQIPQPPPVST 1079
Query 169 GIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQ 222
+ S + P + + AG + P + P + L+ +
Sbjct 1080 ALPSSSAVSRPPIATSAGRSSTAASTSAPLTYPAGDRSHIPGNLRPIYEMLNAE 1133
>sp|Q59YH3|CG11_CANAL G1/S-specific cyclin CCN1 OS=Candida albicans
(strain SC5314 / ATCC MYA-2876) OX=237561 GN=CCN1 PE=1
SV=2
Length=693
Score = 33.2 bits (74), Expect = 5.6, Method: Composition-based stats.
Identities = 16/65 (25%), Positives = 26/65 (40%), Gaps = 0/65 (0%)
Query 133 PVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETS 192
PV PP +++ + + + + N P I S P PPPG + + TS
Sbjct 520 PVTPPSATSQYSLFSNKNNRTHESTSGLNSTCNTPTHISISSFAPPQPPPGSILKPKLTS 579
Query 193 DHQMN 197
+ N
Sbjct 580 INSTN 584
>sp|P0CY18|CG11_CANAX G1/S-specific cyclin CLN1 OS=Candida albicans
OX=5476 GN=CLN1 PE=3 SV=1
Length=698
Score = 33.2 bits (74), Expect = 5.6, Method: Composition-based stats.
Identities = 16/65 (25%), Positives = 26/65 (40%), Gaps = 0/65 (0%)
Query 133 PVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETS 192
PV PP +++ + + + + N P I S P PPPG + + TS
Sbjct 524 PVTPPSATSQYSLFSNKNNRTHESTSGLNSTCNTPTHISISSFAPPQPPPGSILKPKLTS 583
Query 193 DHQMN 197
+ N
Sbjct 584 INSTN 588
>sp|C4YR54|CG11_CANAW G1/S-specific cyclin CCN1 OS=Candida albicans
(strain WO-1) OX=294748 GN=CCN1 PE=3 SV=1
Length=698
Score = 33.2 bits (74), Expect = 5.6, Method: Composition-based stats.
Identities = 16/65 (25%), Positives = 26/65 (40%), Gaps = 0/65 (0%)
Query 133 PVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETS 192
PV PP +++ + + + + N P I S P PPPG + + TS
Sbjct 524 PVTPPSATSQYSLFSNKNNRTHESTSGLNSTCNTPTHISISSFAPPQPPPGSILKPKLTS 583
Query 193 DHQMN 197
+ N
Sbjct 584 INSTN 588
>sp|Q5UNX8|YR722_MIMIV Uncharacterized protein R722 OS=Acanthamoeba
polyphaga mimivirus OX=212035 GN=MIMI_R722 PE=1 SV=1
Length=872
Score = 33.2 bits (74), Expect = 5.9, Method: Composition-based stats.
Identities = 19/126 (15%), Positives = 38/126 (30%), Gaps = 15/126 (12%)
Query 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSI--PENTNFPAGIEPQSNIP 177
VC NPY+ + +PP+ A+ + ++ + P + + +
Sbjct 526 VCGNPYNAGQTVGHYVPPINPEEIDRFNAKRQFAESFNPEMFRPNDPLMYQSPQVDPSCC 585
Query 178 ETPPPGYLSEDGETSD-------------HQMNHSMDAGSPNLSPNPMSPAHNNLDLQPV 224
+ P L SD N + +P +P A++ + Q
Sbjct 586 QKPMDPRLYRPAVPSDPRMGQYMTDPRLFQNGNQTQYQSNPQSNPQFNHQAYSQPNPQAY 645
Query 225 TYCEPA 230
P
Sbjct 646 PQSNPQ 651
>sp|P31257|HXC10_MOUSE Homeobox protein Hox-C10 OS=Mus musculus
OX=10090 GN=Hoxc10 PE=2 SV=1
Length=342
Score = 32.8 bits (73), Expect = 6.1, Method: Composition-based stats.
Identities = 19/125 (15%), Positives = 32/125 (26%), Gaps = 5/125 (4%)
Query 104 RAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPEN 163
R + C + ++K++ VC Y + P +P L ++ +P
Sbjct 94 RPLSSCSYPPSVKEENVCC---MYSAEKRAKSGPEAALYSHPLP--ESCLGEHEVPVPSY 148
Query 164 TNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQP 223
P E + SP L P D Q
Sbjct 149 YRASPSYSALDKTPHCAGANEFEAPFEQRASLNPRTEHLESPQLGGKVSFPETPKSDSQT 208
Query 224 VTYCE 228
+ E
Sbjct 209 PSPNE 213
>sp|O14686|KMT2D_HUMAN Histone-lysine N-methyltransferase 2D OS=Homo
sapiens OX=9606 GN=KMT2D PE=1 SV=2
Length=5537
Score = 33.2 bits (74), Expect = 6.3, Method: Composition-based stats.
Identities = 20/113 (18%), Positives = 31/113 (27%), Gaps = 5/113 (4%)
Query 103 LRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPE 162
L + E+ F K D +P +ETP+ PP P L S
Sbjct 951 LSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVG 1010
Query 163 NTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPA 215
+ + ++ S P P+P+SP
Sbjct 1011 PASPILMEPLPPQCSPLLQHSLVPQNSPPSQCS-----PPALPLSVPSPLSPI 1058
>sp|Q7ZXH3|TAB3_XENLA Mitogen-activated protein kinase kinase
kinase 7-interacting protein 3 homolog OS=Xenopus laevis OX=8355
GN=map3k7ip3 PE=2 SV=1
Length=692
Score = 32.8 bits (73), Expect = 6.6, Method: Composition-based stats.
Identities = 20/107 (19%), Positives = 33/107 (31%), Gaps = 8/107 (7%)
Query 133 PVLPPVLVPRHTEIPAEFPP--LDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGE 190
P P ++P + P YS P+ P S Y S +
Sbjct 231 PPSPQAVLPHYNPCPPYPQSFQPTQYSPKQPQIPQSAFRSPPTSQCTSP----YSSPQHQ 286
Query 191 TSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISY 237
+Q++H SP+ +SP P Y + + + Y
Sbjct 287 VQTNQLSHQTSHVFLPPSPSTVSPHLYQQ--APPPYPKQSSLGYLPY 331
>sp|J9VT33|CUF1_CRYNH Copper-dependent transcription factor 1
OS=Cryptococcus neoformans var. grubii serotype A (strain H99
/ ATCC 208821 / CBS 10515 / FGSC 9487) OX=235443 GN=CUF1 PE=1
SV=1
Length=1048
Score = 32.8 bits (73), Expect = 6.7, Method: Composition-based stats.
Identities = 23/108 (21%), Positives = 40/108 (37%), Gaps = 8/108 (7%)
Query 127 YQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLS 186
+ + +P +P + + PPL ++P +T + + P N P+ PP S
Sbjct 520 FSDMMSPQIPQSV----SPTSYHVPPLQPKPLNLPVSTIHHSTLSPSFNTPQPSPPAVSS 575
Query 187 EDGETS--DHQMNHSMDAGSPNLSPNPMSP--AHNNLDLQPVTYCEPA 230
S H N P + P P+ P A + + P P+
Sbjct 576 PADSLSMAVHPSNGPNVRPVPMIQPRPILPKRASDTGLVMPQGSRPPS 623
>sp|Q3UHH1|ZSWM8_MOUSE Zinc finger SWIM domain-containing protein
8 OS=Mus musculus OX=10090 GN=Zswim8 PE=1 SV=1
Length=1832
Score = 33.2 bits (74), Expect = 6.9, Method: Composition-based stats.
Identities = 17/126 (13%), Positives = 34/126 (27%), Gaps = 6/126 (5%)
Query 111 FAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGI 170
+ + + +P + P P +PR P H +P +
Sbjct 1509 HPYTALQPHLPCSPQYLTHPAHPAHPMPHMPRPAVFPVPSSAYPQGVHPAFLGAQYPYSV 1568
Query 171 EPQSNI-----PETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVT 225
P S P ++ ++ + ++ P PA L P
Sbjct 1569 TPPSLAATAVSFPVPSMAPITVHPYHTEPGLPLPTSVALSSVHPASTFPAIQGASL-PAL 1627
Query 226 YCEPAF 231
+P+
Sbjct 1628 TTQPSP 1633
>sp|Q6J1Y9|UBP19_RAT Ubiquitin carboxyl-terminal hydrolase 19
OS=Rattus norvegicus OX=10116 GN=Usp19 PE=1 SV=1
Length=1357
Score = 32.8 bits (73), Expect = 7.2, Method: Composition-based stats.
Identities = 35/167 (21%), Positives = 53/167 (32%), Gaps = 16/167 (10%)
Query 66 TIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAM---ELCEFAFNMKKDEVCV 122
I ++ DG H PH I +RW +LR + E C F F + ++C+
Sbjct 361 LIFQTRDGNFLRLHPGCGPHTI----FRW-----QVKLRNLIEPEQCTFCFTASRIDICL 411
Query 123 NPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPP 182
QR P V P D + P P + ++ E P
Sbjct 412 RKRQSQRWGGLEAPATRVGGAKVAVPTGPTPLDSTP--PGGGPLPLTGQEEARAVEKEKP 469
Query 183 GYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEP 229
SED ++ +P P+ SP + P P
Sbjct 470 KARSEDSGLDGVVARTPLEHVTPKPEPHLASP--KPTCMVPPMPHSP 514
>sp|Q9NYD6|HXC10_HUMAN Homeobox protein Hox-C10 OS=Homo sapiens
OX=9606 GN=HOXC10 PE=1 SV=2
Length=342
Score = 32.4 bits (72), Expect = 7.3, Method: Composition-based stats.
Identities = 19/125 (15%), Positives = 32/125 (26%), Gaps = 5/125 (4%)
Query 104 RAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPEN 163
R + C + ++K++ VC Y + P +P L ++ +P
Sbjct 94 RPLSSCSYPPSVKEENVCC---MYSAEKRAKSGPEAALYSHPLP--ESCLGEHEVPVPSY 148
Query 164 TNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQP 223
P E + SP L P D Q
Sbjct 149 YRASPSYSALDKTPHCSGANDFEAPFEQRASLNPRAEHLESPQLGGKVSFPETPKSDSQT 208
Query 224 VTYCE 228
+ E
Sbjct 209 PSPNE 213
>sp|A2T7H7|HXC10_PONPY Homeobox protein Hox-C10 OS=Pongo pygmaeus
OX=9600 GN=HOXC10 PE=3 SV=1
Length=342
Score = 32.4 bits (72), Expect = 7.4, Method: Composition-based stats.
Identities = 19/125 (15%), Positives = 32/125 (26%), Gaps = 5/125 (4%)
Query 104 RAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPEN 163
R + C + ++K++ VC Y + P +P L ++ +P
Sbjct 94 RPLSSCSYPPSVKEENVCC---MYSAEKRAKSGPEAALYSHPLP--ESCLGEHEVPVPSY 148
Query 164 TNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQP 223
P E + SP L P D Q
Sbjct 149 YRASPNYSALDKTPHCSGANDFEAPFEQRASLNPRTEHLESPQLGGKVSFPETPKSDSQT 208
Query 224 VTYCE 228
+ E
Sbjct 209 PSPNE 213
>sp|Q8BT14|CNOT4_MOUSE CCR4-NOT transcription complex subunit
4 OS=Mus musculus OX=10090 GN=Cnot4 PE=1 SV=2
Length=575
Score = 32.4 bits (72), Expect = 8.0, Method: Composition-based stats.
Identities = 19/130 (15%), Positives = 38/130 (29%), Gaps = 5/130 (4%)
Query 98 HSHHELRAMELCEFAFNMKKDEVCV----NPYHYQRVETPVLPPVLVPRHTEIPAEFPPL 153
+ +++ ++ + + D + + N +TP PP L + IP
Sbjct 261 KNKNKVTPLQRYDTPIDKPSDSLSIGNGDNSQQISNSDTPSPPPGLSKSNPVIPISSSNH 320
Query 154 DDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMS 213
S T + P P P L + + +L +
Sbjct 321 SARSPFEGAVTESQSLFSDNFRHPN-PIPSGLPPFPSSPQTPSDWPTAPEPQSLFTSETI 379
Query 214 PAHNNLDLQP 223
P ++ D Q
Sbjct 380 PVSSSTDWQA 389
>sp|Q6BXI1|SEC16_DEBHA COPII coat assembly protein SEC16 OS=Debaryomyces
hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394
/ JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=SEC16 PE=3
SV=2
Length=2130
Score = 32.8 bits (73), Expect = 8.5, Method: Composition-based stats.
Identities = 12/98 (12%), Positives = 25/98 (26%), Gaps = 5/98 (5%)
Query 130 VETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDG 189
V P P + + P +P+ TN G + + PPP ++ +
Sbjct 708 VVNPYAKPAMNTVVSPPMNYAQPPG-----MPQVTNNRGGSHLPAGMVAPPPPSQITGNN 762
Query 190 ETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYC 227
H + + + +
Sbjct 763 NVLPHAQPQPFPNMQNQNLGQNTNSYAPSRKISNPSPN 800
>sp|Q9UIF9|BAZ2A_HUMAN Bromodomain adjacent to zinc finger domain
protein 2A OS=Homo sapiens OX=9606 GN=BAZ2A PE=1 SV=4
Length=1905
Score = 32.8 bits (73), Expect = 8.8, Method: Composition-based stats.
Identities = 13/70 (19%), Positives = 22/70 (31%), Gaps = 0/70 (0%)
Query 161 PENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLD 220
P+ F + N TPPP + S Q+ S P+ + ++
Sbjct 1319 PQALWFNISAQMPCNAAPTPPPAVSEDQPTPSPQQLASSKPMNRPSAANPCSPVQFSSTP 1378
Query 221 LQPVTYCEPA 230
L + A
Sbjct 1379 LAGLAPKRRA 1388
>sp|A7MKW3|ZIPA_CROS8 Cell division protein ZipA OS=Cronobacter
sakazakii (strain ATCC BAA-894) OX=290339 GN=zipA PE=3 SV=1
Length=319
Score = 32.1 bits (71), Expect = 8.8, Method: Composition-based stats.
Identities = 16/105 (15%), Positives = 23/105 (22%), Gaps = 7/105 (7%)
Query 133 PVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIP------ETPPPGYLS 186
P P P+H P P P P P
Sbjct 77 PESAPARQPQHNYQPPYAPSQPRQPVREPVEPEPEVAYREAPQAPLHQPQEPQPVRQTAP 136
Query 187 EDGETSDHQMNHSMDAGSPNLSPNPMS-PAHNNLDLQPVTYCEPA 230
+ + + Q A P P P P + + +P
Sbjct 137 QPSQPAPAQPAMRQPAPQPVTEPAPQPEPVAEPVPVSAPEKPQPK 181
>sp|Q3UH66|WNK2_MOUSE Serine/threonine-protein kinase WNK2 OS=Mus
musculus OX=10090 GN=Wnk2 PE=1 SV=2
Length=2149
Score = 32.8 bits (73), Expect = 8.9, Method: Composition-based stats.
Identities = 17/109 (16%), Positives = 29/109 (27%), Gaps = 2/109 (2%)
Query 124 PYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPG 183
P H P V + + PPL + P+ P P
Sbjct 756 PSHLPPYLAPTSQVVAPAQLKPLQMPQPPLQPLAQVPPQMPQMPVVPPITPLTGLDGLPQ 815
Query 184 YLSEDGETSDHQMNHSMDAGSPNLSPNPMS--PAHNNLDLQPVTYCEPA 230
L++ + + + P+ + P L +Q V P
Sbjct 816 TLTDLPAANVAPVPPPQYFSPAVILPSLTTPLPTSPALPMQAVKLPHPP 864
>sp|J9VND4|PBP1_CRYNH PAB1-binding protein 1 OS=Cryptococcus neoformans
var. grubii serotype A (strain H99 / ATCC 208821 /
CBS 10515 / FGSC 9487) OX=235443 GN=PBP1 PE=1 SV=2
Length=785
Score = 32.4 bits (72), Expect = 9.0, Method: Composition-based stats.
Identities = 15/100 (15%), Positives = 28/100 (28%), Gaps = 3/100 (3%)
Query 132 TPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGET 191
+P P +P +PP + +P P G++ P P + G+
Sbjct 592 SPSPHPAQPAMMPGMPPNYPPYGRFQPGMPPPYGVPGGMQNPMFSPG---PHFSPHPGQP 648
Query 192 SDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
+ PN+ + N P +
Sbjct 649 MGQPQHMMPGGPQPNMPMYFQNGMPQNPAFLPPQMQQFPH 688
>sp|Q01443|SSP2_PLAYO Sporozoite surface protein 2 OS=Plasmodium
yoelii yoelii OX=73239 GN=SSP2 PE=1 SV=2
Length=827
Score = 32.4 bits (72), Expect = 9.2, Method: Composition-based stats.
Identities = 17/79 (22%), Positives = 28/79 (35%), Gaps = 4/79 (5%)
Query 157 SHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMN----HSMDAGSPNLSPNPM 212
+ + P N N P+ SN E P S E S+ + P+ P+
Sbjct 472 NPNEPSNPNAPSNPNEPSNPNEPSNPNEPSNPNEPSNPNEPSNPKKPSNPNEPSNPNEPL 531
Query 213 SPAHNNLDLQPVTYCEPAF 231
+P + +P EP+
Sbjct 532 NPNEPSNPNEPSNPNEPSN 550
>sp|Q7Z429|LFG1_HUMAN Protein lifeguard 1 OS=Homo sapiens OX=9606
GN=GRINA PE=1 SV=1
Length=371
Score = 32.1 bits (71), Expect = 9.9, Method: Composition-based stats.
Identities = 16/93 (17%), Positives = 23/93 (25%), Gaps = 0/93 (0%)
Query 139 LVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNH 198
P + P PP + P + P+ P G + +
Sbjct 33 AQPPYPGAPYPQPPFQPSPYGQPGYPHGPSPYPQGGYPQGPYPQGGYPQGPYPQEGYPQG 92
Query 199 SMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAF 231
G P P SP N QP +
Sbjct 93 PYPQGGYPQGPYPQSPFPPNPYGQPQVFPGQDP 125
Lambda K H a alpha
0.317 0.124 0.349 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0380 0.140 1.90 42.6 43.6
Effective search space used: 41816195296
Search has CONVERGED!
Database: uniprot_sprot.fasta
Posted date: Apr 3, 2024 12:05 PM
Number of letters in database: 206,678,396
Number of sequences in database: 571,282
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40