Contact Molecules for Homologous Proteins | ||||
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PID | QueryLength | Homolgous Sequence in PDB | UniProt Query | TITLE |
3177154 | 468 | 115 | P08887(IL6RA_HUMAN) | RecName: Full=Interleukin-6 receptor subunit alpha ; Short=IL-6 receptor subunit alpha; Short=IL-6R subunit alpha; Short=IL-6R-alpha; Short=IL-6RA;AltName: Full=IL-6R 1;AltName: Full=Membrane glycoprotein 80; Short=gp80;AltName: CD_antigen=CD126;Contains: RecName: Full=Soluble interleukin-6 receptor subunit alpha ; Short=sIL6R ;Flags: Precursor; |
QUERYSEQ |
MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLV RKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ GEWSEWSPEAMGTPWTESRSPPAENEVSTPMQALTTNKDDDNILFRDSANATSLPVQDSSSVPLPTFLVAGGSLAFGTLLCIAIVLRFKKTWKLRALKEGKTSMHPPYSLGQLVPERPRPTPVLVPLISPPVSPSSLGSDNTSSHNRPDA RDPRSPYDISNTDYFFPR |
468 | region | name | description |
1-19 | SIGNAL | ||
20-468 | CHAIN | /note="Interleukin-6 receptor subunit alpha" /id="PRO_0000010895" | |
20-355 | CHAIN | /note="Soluble interleukin-6 receptor subunit alpha" /id="PRO_0000450730" | |
20-365 | TOPO_DOM | /note="Extracellular" | |
366-386 | TRANSMEM | /note="Helical" | |
387-468 | TOPO_DOM | /note="Cytoplasmic" | |
26-112 | DOMAIN | /note="Ig-like C2-type" | |
113-217 | DOMAIN | /note="Fibronectin type-III 1" | |
218-316 | DOMAIN | /note="Fibronectin type-III 2" | |
303-328 | REGION | /note="Disordered" | |
421-468 | REGION | /note="Disordered" | |
311-328 | COMPBIAS | /note="Polar residues" | |
1-468 | DISORDER | predicted by DISOPRED |
MONOMER | |||||||
468 | |||||||
pdb_id | a1 | identity[%]2 | description | ||||
1n26 | A | 100.0 | IL6A_HUMAN IL-6 Receptor alpha chain | ||||
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue. |
HETERO | |||||||
468 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
3hmx[1] | C | USTEKINUMAB FAB LIGHT CHAIN[214 aa] | A | 14.3 /29.0 |
7 /9 |
IL12B_HUMAN Interleukin-12 subunit beta | |
4i18[1] | C | antibody light chain[215 aa] | E | 60.0 /24.9 |
5 /5 |
PRLR_HUMAN Prolactin receptor | |
8iow[2] | C | Light chain of Sarilumab Fab[212 aa] | A | 100.0 /100.0 |
6 /6 |
IL6RA_HUMAN Interleukin-6 receptor subunit alpha | |
8d82[2] | C | IL6RB_HUMAN Interleukin-6 receptor subunit beta[589 aa] | A | 100.0 /100.0 |
11 /11 |
IL6RA_HUMAN Soluble interleukin-6 receptor subunit alpha | |
8d82[2] | F | IL6RB_HUMAN Interleukin-6 receptor subunit beta[589 aa] | A | 100.0 /100.0 |
6 /6 |
IL6RA_HUMAN Soluble interleukin-6 receptor subunit alpha | |
8iow[1] | D | Heavy chain of Sarilumab Fab[207 aa] | A | 100.0 /100.0 |
12 /12 |
IL6RA_HUMAN Interleukin-6 receptor subunit alpha | |
8j6f[1] | A | Heavy chain of Tocilizumab Fab[211 aa] | C | 100.0 /100.0 |
14 /14 |
IL6RA_HUMAN Interleukin-6 receptor subunit alpha | |
8j6f[1] | D | IL6RA_HUMAN IL6R-D2 peptide[10 aa] | C | 100.0 /100.0 |
6 /6 |
IL6RA_HUMAN Interleukin-6 receptor subunit alpha | |
8qy4[6] | B | IL6RB_MOUSE Interleukin-6 receptor subunit beta[583 aa] | E | 41.7 /31.7 |
12 /12 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
8qy4[6] | D | IL6RB_MOUSE Interleukin-6 receptor subunit beta[583 aa] | E | 0.0 /31.7 |
6 /6 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
7dc8[2] | A | Switch Ab Fab light chain[212 aa] | C | 100.0 /99.5 |
5 /5 |
IL6RA_HUMAN Interleukin-6 receptor subunit alpha | |
7dc8[2] | B | Switch Ab Fab heavy chain[209 aa] | C | 100.0 /99.5 |
9 /9 |
IL6RA_HUMAN Interleukin-6 receptor subunit alpha | |
5fuc[1] | E | VHH6[110 aa] | C | 100.0 /99.0 |
10 /10 |
D6R9R8_HUMAN IL6RA_HUMAN INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, INTERLEUKIN-.. | |
5fuc[1] | A | IL6_HUMAN INTERLEUKIN-6[152 aa] | D | 100.0 /99.0 |
12 /12 |
D6R9R8_HUMAN IL6RA_HUMAN INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, INTERLEUKIN-.. | |
5fuc[1] | F | VHH6[124 aa] | D | 100.0 /99.0 |
10 /10 |
D6R9R8_HUMAN IL6RA_HUMAN INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, INTERLEUKIN-.. | |
1p9m[2] | A | IL6RB_HUMAN Interleukin-6 receptor beta chain[298 aa] | C | 100.0 /100.0 |
12 /12 |
IL6RA_HUMAN Interleukin-6 receptor alpha chain | |
1p9m[2] | A | IL6RB_HUMAN Interleukin-6 receptor beta chain[298 aa] | C | 100.0 /100.0 |
8 /8 |
IL6RA_HUMAN Interleukin-6 receptor alpha chain | |
7u7n[1] | B | IL6RB_HUMAN Interleukin-6 receptor subunit beta[298 aa] | C | 33.3 /26.7 |
3 /3 |
IL27B_HUMAN Interleukin-27 subunit beta | |
8d85[1] | D | IL6RB_HUMAN Interleukin-6 receptor subunit beta[296 aa] | A | 0.0 /26.7 |
2 /3 |
IL27B_HUMAN Interleukin-27 subunit beta | |
8dps[8] | A | IL6RB_HUMAN Interleukin-6 receptor subunit beta[297 aa] | C | 36.4 /33.9 |
11 /11 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
8dps[8] | D | IL6RB_HUMAN Interleukin-6 receptor subunit beta[297 aa] | C | 0.0 /33.9 |
4 /4 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
8d74[1] | B | CNTF_HUMAN Ciliary neurotrophic factor[174 aa] | A | 33.3 /29.9 |
12 /12 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8d74[1] | B | CNTF_HUMAN Ciliary neurotrophic factor[174 aa] | C | 14.3 /34.7 |
14 /14 |
CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha.. | |
8d74[2] | A | IL6RB_HUMAN Interleukin-6 receptor subunit beta[392 aa] | C | 36.4 /34.7 |
11 /11 |
CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha.. | |
8dpt[2] | A | IL6RB_HUMAN Interleukin-6 receptor subunit beta[398 aa] | C | 33.3 /34.2 |
15 /15 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
8dpt[2] | D | IL6RB_HUMAN Interleukin-6 receptor subunit beta[398 aa] | C | 0.0 /34.2 |
3 /3 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
8d7e[1] | B | H4H25311P2 antibody Fab fragment light chain[215 a.. | A | 33.3 /33.9 |
9 /9 |
CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha.. | |
8d7e[1] | C | H4H25311P2 antibody Fab fragment heavy chain[217 a.. | A | 27.3 /33.9 |
11 /11 |
CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha.. | |
8d7e[1] | E | REGN8938 antibody Fab fragment heavy chain[214 aa].. | A | 0.0 /33.9 |
3 /11 |
CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha.. | |
8dps[10] | B | IL11_HUMAN Interleukin-11[165 aa] | A | 40.0 /28.5 |
10 /10 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8dps[12] | B | IL11_HUMAN Interleukin-11[165 aa] | C | 6.7 /33.9 |
15 /18 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
8dpt[2] | E | IL11_HUMAN Interleukin-11[165 aa] | A | 0.0 /28.6 |
1 /10 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8qy4[2] | A | IL11_HUMAN Interleukin-11[165 aa] | E | 0.0 /31.7 |
10 /15 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
8upa[2] | A | De novo designed IL-6 mimetic[56 aa] | B | 37.5 /29.9 |
16 /16 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
1f45[1] | B | I12A_HUMAN INTERLEUKIN-12 ALPHA CHAIN[133 aa] | A | 25.0 /30.4 |
20 /21 |
I12B_HUMAN INTERLEUKIN-12 BETA CHAIN | |
1pvh[2] | B | LIF_HUMAN Leukemia inhibitory factor[169 aa] | A | 23.1 /29.9 |
13 /13 |
IL6RB_HUMAN Interleukin-6 receptor beta chain | |
8d6a[1] | A | LIF_HUMAN Leukemia inhibitory factor[169 aa] | B | 30.0 /29.9 |
10 /10 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8d74[2] | C | CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha.. | A | 18.2 /29.9 |
11 /11 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8d7h[3] | B | CLCF1_HUMAN Cardiotrophin-like cytokine factor 1[178 aa] | A | 12.5 /33.9 |
16 /17 |
CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha.. | |
8d7h[3] | B | CLCF1_HUMAN Cardiotrophin-like cytokine factor 1[178 aa] | C | 9.1 /29.6 |
11 /13 |
CRLF1_HUMAN Cytokine receptor-like factor 1 | |
8d7h[2] | E | CLCF1_HUMAN Cardiotrophin-like cytokine factor 1[178 aa] | C | 20.0 /29.6 |
5 /11 |
CRLF1_HUMAN Cytokine receptor-like factor 1 | |
3d85[4] | C | IL23A_HUMAN Interleukin-23 subunit p19[133 aa] | D | 12.5 /28.3 |
16 /17 |
IL12B_HUMAN Interleukin-12 subunit p40 | |
4grw[8] | A | IL23A_HUMAN Interleukin-23 subunit alpha[130 aa] | B | 18.8 /29.2 |
16 /17 |
IL12B_HUMAN Interleukin-12 subunit beta | |
8cr8[1] | B | IL23A_HUMAN Interleukin-23 subunit alpha[138 aa] | A | 14.3 /29.8 |
14 /15 |
IL12B_HUMAN Interleukin-12 subunit beta | |
3d87[6] | A | IL23A_HUMAN Interleukin-23 subunit p19[161 aa] | B | 16.7 /28.8 |
18 /19 |
IL12B_HUMAN Interleukin-12 subunit p40 | |
3d87[1] | C | IL23A_HUMAN Interleukin-23 subunit p19[159 aa] | B | 0.0 /28.8 |
2 /2 |
IL12B_HUMAN Interleukin-12 subunit p40 | |
5mzv[1] | B | IL23A_HUMAN Interleukin-23 subunit alpha[137 aa] | A | 18.8 /28.0 |
16 /17 |
IL12B_HUMAN Interleukin-12 subunit beta | |
5mzv[1] | C | IL23R_HUMAN Interleukin-23 receptor[293 aa] | A | 0.0 /28.0 |
2 /6 |
IL12B_HUMAN Interleukin-12 subunit beta | |
6wdq[1] | C | IL23R_HUMAN Interleukin-23 receptor[293 aa] | A | 66.7 /28.3 |
3 /5 |
IL12B_HUMAN Interleukin-12 subunit beta | |
8oe4[1] | C | IL23R_HUMAN CALM1_HUMAN Interleukin-23 receptor,Calmodulin-1[293 aa] | A | 0.0 /29.3 |
1 /1 |
IL12B_HUMAN Interleukin-12 subunit beta | |
8oe4[1] | D | I12R1_HUMAN DAPK1_HUMAN Interleukin-12 receptor subunit beta-1,Death-assoc.. | A | 0.0 /29.3 |
8 /16 |
IL12B_HUMAN Interleukin-12 subunit beta | |
3hmx[1] | B | IL12A_HUMAN Interleukin-12 subunit alpha[176 aa] | A | 17.6 /29.0 |
17 /18 |
IL12B_HUMAN Interleukin-12 subunit beta | |
3hmx[1] | D | USTEKINUMAB FAB HEAVY CHAIN[217 aa] | A | 25.0 /29.0 |
12 /13 |
IL12B_HUMAN Interleukin-12 subunit beta | |
3qwr[1] | C | ADNECTIN[91 aa] | A | 28.6 /28.9 |
21 /22 |
IL12B_HUMAN Interleukin-12 subunit beta | |
8d82[2] | A | IL6RA_HUMAN Soluble interleukin-6 receptor subunit alpha[296 a.. | C | 9.1 /28.6 |
11 /11 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
6uib[1] | C | Peptide 23-652[15 aa] | B | 25.0 /28.6 |
12 /12 |
IL12B_HUMAN Interleukin-12 subunit beta | |
5njd[1] | J | IL23A_HUMAN Interleukin-23 subunit alpha[141 aa] | I | 18.8 /28.6 |
16 /16 |
IL12B_HUMAN Interleukin-12 subunit beta | |
3duh[1] | D | IL23A_HUMAN Interleukin-23 subunit alpha[137 aa] | B | 12.5 /28.5 |
16 /17 |
IL12B_HUMAN Interleukin-12 subunit beta | |
4grw[2] | G | Nanobody 124C4[125 aa] | B | 23.1 /29.2 |
13 /15 |
IL12B_HUMAN Interleukin-12 subunit beta | |
4grw[2] | J | Nanobody 37D5[122 aa] | B | 75.0 /29.2 |
4 /4 |
IL12B_HUMAN Interleukin-12 subunit beta | |
8dpt[8] | C | I11RA_HUMAN Interleukin-11 receptor subunit alpha[294 aa] | A | 9.1 /28.6 |
11 /12 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
5njd[6] | U | Briakinumab FAb Light chain[215 aa] | A | 0.0 /27.9 |
3 /8 |
IL12B_HUMAN Interleukin-12 subunit beta | |
5njd[6] | V | Briakinumab FAb Heavy chain[205 aa] | A | 0.0 /27.9 |
2 /10 |
IL12B_HUMAN Interleukin-12 subunit beta | |
1i1r[2] | B | Q98823_HHV8 VIRAL IL-6[167 aa] | A | 36.4 /28.2 |
11 /11 |
IL6RB_HUMAN INTERLEUKIN-6 RECEPTOR BETA CHAIN | |
6wdq[6] | D | I12R1_HUMAN Interleukin-12 receptor subunit beta-1[109 aa] | A | 0.0 /28.3 |
8 /14 |
IL12B_HUMAN Interleukin-12 subunit beta | |
8xrp[5] | A | IL12A_HUMAN Interleukin-12 subunit alpha[185 aa] | B | 14.3 /28.2 |
14 /15 |
IL12B_HUMAN Interleukin-12 subunit beta | |
8xrp[4] | M | IL12A_HUMAN Interleukin-12 subunit alpha[185 aa] | B | 66.7 /28.2 |
3 /3 |
IL12B_HUMAN Interleukin-12 subunit beta | |
8xrp[4] | O | I12R2_HUMAN Interleukin-12 receptor subunit beta-2[291 aa] | B | 100.0 /28.2 |
1 /1 |
IL12B_HUMAN Interleukin-12 subunit beta | |
4grw[3] | H | Nanobody 22E11[123 aa] | B | 0.0 /29.2 |
10 /17 |
IL12B_HUMAN Interleukin-12 subunit beta | |
7u7n[1] | D | IL27A_HUMAN Interleukin-27 subunit alpha[191 aa] | B | 0.0 /28.9 |
1 /12 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
7u7n[2] | D | IL27A_HUMAN Interleukin-27 subunit alpha[191 aa] | C | 0.0 /26.7 |
20 /21 |
IL27B_HUMAN Interleukin-27 subunit beta | |
7u7n[2] | A | I27RA_HUMAN Interleukin-27 receptor subunit alpha[195 aa] | C | 40.0 /26.7 |
10 /10 |
IL27B_HUMAN Interleukin-27 subunit beta | |
7z0l[1] | B | IL27B_MOUSE IL27A_MOUSE Interleukin-27 subunit beta,Interleukin-27 subunit.. | A | 0.0 /26.3 |
1 /14 |
IL6RB_MOUSE Interleukin-6 receptor subunit beta | |
1p9m[4] | B | IL6_HUMAN Interleukin-6[163 aa] | A | 33.3 /28.9 |
12 /12 |
IL6RB_HUMAN Interleukin-6 receptor beta chain | |
1p9m[2] | B | IL6_HUMAN Interleukin-6[163 aa] | C | 100.0 /100.0 |
15 /15 |
IL6RA_HUMAN Interleukin-6 receptor alpha chain | |
5fuc[1] | B | IL6_HUMAN INTERLEUKIN-6[160 aa] | C | 100.0 /99.0 |
18 /18 |
D6R9R8_HUMAN IL6RA_HUMAN INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, INTERLEUKIN-.. | |
8d82[2] | B | IL6_HUMAN Interleukin-6[169 aa] | A | 100.0 /100.0 |
12 /12 |
IL6RA_HUMAN Soluble interleukin-6 receptor subunit alpha | |
8qy5[4] | B | IL6_HUMAN Interleukin-6[157 aa] | A | 11.1 /26.1 |
9 /10 |
IL6RB_MOUSE Interleukin-6 receptor subunit beta | |
8qy5[4] | B | IL6_HUMAN Interleukin-6[157 aa] | C | 100.0 /100.0 |
11 /11 |
IL6RA_HUMAN Interleukin-6 receptor subunit alpha | |
1p9m[2] | C | IL6RA_HUMAN Interleukin-6 receptor alpha chain[201 aa] | A | 10.0 /28.9 |
10 /11 |
IL6RB_HUMAN Interleukin-6 receptor beta chain | |
8qy5[4] | C | IL6RA_HUMAN Interleukin-6 receptor subunit alpha[201 aa] | A | 9.1 /26.1 |
11 /11 |
IL6RB_MOUSE Interleukin-6 receptor subunit beta | |
8dps[2] | C | I11RA_HUMAN Interleukin-11 receptor subunit alpha[200 aa] | A | 10.0 /28.5 |
10 /11 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8qy4[2] | E | I11RA_HUMAN Interleukin-11 receptor subunit alpha[197 aa] | B | 9.1 /26.1 |
11 /11 |
IL6RB_MOUSE Interleukin-6 receptor subunit beta | |
3mzg[9] | A | PRL_HUMAN Prolactin[186 aa] | B | 0.0 /24.7 |
21 /22 |
PRLR_HUMAN Prolactin receptor | |
3ew3[1] | A | PRL_HUMAN Prolactin[185 aa] | B | 0.0 /25.4 |
20 /21 |
PRLR_RAT Prolactin receptor | |
3d48[1] | A | PRL_HUMAN Prolactin[165 aa] | B | 0.0 /25.1 |
21 /22 |
PRLR_HUMAN Prolactin receptor | |
4i18[1] | D | antibody heavy chain[220 aa] | E | 20.0 /24.9 |
20 /21 |
PRLR_HUMAN Prolactin receptor | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
COMPOUND | |||||||
468 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
1n26[2] | H |
CYS
CYSTEINE[7 atoms] |
A | 100.0 /100.0 |
5 /5 |
IL6A_HUMAN IL-6 Receptor alpha chain | |
7dc8[2] | H |
ATP
ADENOSINE-5'-TRIPHOSPHATE[31 atoms] |
C | 100.0 /99.5 |
1 /1 |
IL6RA_HUMAN Interleukin-6 receptor subunit alpha | |
1n26[6] | D |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
A | 100.0 /100.0 |
5 /5 |
IL6A_HUMAN IL-6 Receptor alpha chain | |
1n26[27] | E |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
A | 100.0 /100.0 |
3 /3 |
IL6A_HUMAN IL-6 Receptor alpha chain | |
1n26[1] | E |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
A | 100.0 /100.0 |
3 /3 |
IL6A_HUMAN IL-6 Receptor alpha chain | |
3duh[3] | E |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
A | 0.0 /28.6 |
2 /7 |
IL12B_HUMAN Interleukin-12 subunit beta | |
5fuc[3] | G |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
C | 100.0 /99.0 |
3 /3 |
D6R9R8_HUMAN IL6RA_HUMAN INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, INTERLEUKIN-.. | |
6o4p[7] | E |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
A | 50.0 /35.0 |
4 /4 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
7u7n[2] | K |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
B | 0.0 /28.9 |
1 /2 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
7z0l[1] | J |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
A | 50.0 /26.3 |
2 /2 |
IL6RB_MOUSE Interleukin-6 receptor subunit beta | |
8d74[2] | P |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
C | 0.0 /34.7 |
1 /1 |
CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha.. | |
8d7h[2] | V |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
C | 0.0 /29.6 |
1 /1 |
CRLF1_HUMAN Cytokine receptor-like factor 1 | |
8d82[2] | S |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
A | 100.0 /100.0 |
3 /3 |
IL6RA_HUMAN Soluble interleukin-6 receptor subunit alpha | |
8d82[3] | T |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
C | 100.0 /28.6 |
1 /1 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8d85[1] | H |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
A | 16.7 /26.7 |
6 /6 |
IL27B_HUMAN Interleukin-27 subunit beta | |
8iow[1] | F |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
A | 100.0 /100.0 |
3 /3 |
IL6RA_HUMAN Interleukin-6 receptor subunit alpha | |
8qy4[2] | P |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
B | 0.0 /26.1 |
3 /3 |
IL6RB_MOUSE Interleukin-6 receptor subunit beta | |
8qy4[6] | Q |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
B | 33.3 /26.1 |
3 /3 |
IL6RB_MOUSE Interleukin-6 receptor subunit beta | |
8upa[2] | E |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
B | 50.0 /29.9 |
2 /2 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
8upa[2] | F |
NAG
2-acetamido-2-deoxy-beta-D-glucopyranose[14 atoms].. |
B | 0.0 /29.9 |
3 /3 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
1f42[1] | C |
MNB
5-MERCAPTO-2-NITRO-BENZOIC ACID[13 atoms] |
A | 66.7 /28.9 |
3 /3 |
I12B_HUMAN INTERLEUKIN-12 BETA CHAIN | |
1f42[1] | D |
MNB
5-MERCAPTO-2-NITRO-BENZOIC ACID[13 atoms] |
A | 50.0 /28.9 |
6 /6 |
I12B_HUMAN INTERLEUKIN-12 BETA CHAIN | |
3d87[1] | G |
MAN
alpha-D-mannopyranose[11 atoms] |
D | 0.0 /28.9 |
4 /4 |
IL12B_HUMAN Interleukin-12 subunit p40 | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
METAL | |||||||
468 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
1pvh[1] | E |
IOD
IODIDE ION[1 atoms] |
A | 100.0 /29.9 |
1 /1 |
IL6RB_HUMAN Interleukin-6 receptor beta chain | |
8cr8[1] | D |
TB
TERBIUM(III) ION[1 atoms] |
A | 0.0 /29.8 |
1 /2 |
IL12B_HUMAN Interleukin-12 subunit beta | |
3d87[2] | F |
K
POTASSIUM ION[1 atoms] |
B | 50.0 /28.8 |
2 /2 |
IL12B_HUMAN Interleukin-12 subunit p40 | |
3mzg[7] | C |
NA
SODIUM ION[1 atoms] |
B | 0.0 /24.7 |
2 /2 |
PRLR_HUMAN Prolactin receptor | |
3mzg[7] | E |
NA
SODIUM ION[1 atoms] |
B | 40.0 /24.7 |
5 /5 |
PRLR_HUMAN Prolactin receptor | |
3mzg[7] | F |
NA
SODIUM ION[1 atoms] |
B | 0.0 /24.7 |
5 /5 |
PRLR_HUMAN Prolactin receptor | |
3nce[1] | C |
NA
SODIUM ION[1 atoms] |
B | 0.0 /24.7 |
2 /3 |
PRLR_HUMAN Prolactin receptor | |
5mj3[1] | H |
NA
SODIUM ION[1 atoms] |
A | 33.3 /28.3 |
3 /3 |
IL12B_HUMAN Interleukin-12 subunit beta | |
5mj3[1] | I |
NA
SODIUM ION[1 atoms] |
A | 0.0 /28.3 |
3 /3 |
IL12B_HUMAN Interleukin-12 subunit beta | |
5mzv[1] | K |
NA
SODIUM ION[1 atoms] |
A | 100.0 /28.0 |
1 /1 |
IL12B_HUMAN Interleukin-12 subunit beta | |
3mzg[7] | D |
CL
CHLORIDE ION[1 atoms] |
B | 50.0 /24.7 |
2 /2 |
PRLR_HUMAN Prolactin receptor | |
5mzv[1] | J |
CL
CHLORIDE ION[1 atoms] |
A | 0.0 /28.0 |
2 /3 |
IL12B_HUMAN Interleukin-12 subunit beta | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
OTHERPOLY | |||||||
468 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
1n26[2] | B | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-al.. | A | 100.0 /100.0 |
9 /9 |
IL6A_HUMAN IL-6 Receptor alpha chain | |
1f42[2] | B | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-be.. | A | 0.0 /28.9 |
3 /7 |
I12B_HUMAN INTERLEUKIN-12 BETA CHAIN | |
8cr8[1] | C | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. | A | 25.0 /29.8 |
4 /9 |
IL12B_HUMAN Interleukin-12 subunit beta | |
3qwr[2] | D | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. | A | 0.0 /28.9 |
3 /7 |
IL12B_HUMAN Interleukin-12 subunit beta | |
5mxa[1] | C | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. | B | 0.0 /28.0 |
2 /8 |
IL12B_HUMAN Interleukin-12 subunit beta | |
6o4p[1] | C | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. | A | 0.0 /35.0 |
5 /5 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
3l5h[1] | C | beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1.. | A | 0.0 /28.8 |
1 /1 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3hmx[3] | E | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose.. | A | 0.0 /29.0 |
3 /7 |
IL12B_HUMAN Interleukin-12 subunit beta | |
4grw[8] | K | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose.. | B | 0.0 /29.2 |
3 /9 |
IL12B_HUMAN Interleukin-12 subunit beta | |
6wdq[1] | E | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. | A | 0.0 /28.3 |
1 /2 |
IL12B_HUMAN Interleukin-12 subunit beta | |
7u7n[1] | H | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. | C | 16.7 /26.7 |
6 /6 |
IL27B_HUMAN Interleukin-27 subunit beta | |
8dps[4] | H | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. | C | 0.0 /33.9 |
3 /3 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
8dpu[6] | T | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. | C | 16.7 /35.3 |
6 /6 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
8xrp[5] | Q | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. | B | 25.0 /28.2 |
4 /8 |
IL12B_HUMAN Interleukin-12 subunit beta | |
5mzv[1] | E | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. | A | 25.0 /28.0 |
4 /10 |
IL12B_HUMAN Interleukin-12 subunit beta | |
1n26[2] | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | A | 100.0 /100.0 |
5 /5 |
IL6A_HUMAN IL-6 Receptor alpha chain | |
3l5h[4] | B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | A | 50.0 /28.8 |
2 /2 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
6o4p[1] | D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | B | 0.0 /35.4 |
4 /4 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
6uib[1] | D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | B | 0.0 /28.6 |
4 /7 |
IL12B_HUMAN Interleukin-12 subunit beta | |
7z0l[4] | F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | A | 20.0 /26.3 |
5 /5 |
IL6RB_MOUSE Interleukin-6 receptor subunit beta | |
8d74[5] | F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | C | 40.0 /34.7 |
5 /5 |
CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha.. | |
8d7e[3] | H | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | A | 50.0 /33.9 |
2 /4 |
CNTFR_HUMAN Ciliary neurotrophic factor receptor subunit alpha.. | |
8d7h[2] | M | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | C | 0.0 /29.6 |
2 /2 |
CRLF1_HUMAN Cytokine receptor-like factor 1 | |
8d82[2] | G | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | A | 100.0 /100.0 |
1 /1 |
IL6RA_HUMAN Soluble interleukin-6 receptor subunit alpha | |
8qy4[2] | I | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | E | 40.0 /31.7 |
5 /5 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
8qy4[2] | J | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | E | 0.0 /31.7 |
5 /5 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
8qy5[4] | J | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | A | 0.0 /26.1 |
4 /4 |
IL6RB_MOUSE Interleukin-6 receptor subunit beta | |
8qy5[4] | K | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a.. | A | 0.0 /26.1 |
5 /5 |
IL6RB_MOUSE Interleukin-6 receptor subunit beta | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
HOMO | |||||||
468 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
1n26[1] | A | IL6A_HUMAN IL-6 Receptor alpha chain[299 aa] | A | 100.0 /100.0 |
11 /11 |
IL6A_HUMAN IL-6 Receptor alpha chain | |
1n26[1] | A | IL6A_HUMAN IL-6 Receptor alpha chain[299 aa] | A | 100.0 /100.0 |
15 /15 |
IL6A_HUMAN IL-6 Receptor alpha chain | |
8iow[1] | B | IL6RA_HUMAN Interleukin-6 receptor subunit alpha[14 aa] | A | 100.0 /100.0 |
8 /8 |
IL6RA_HUMAN Interleukin-6 receptor subunit alpha | |
1bqu[1] | B | IL6RB_HUMAN PROTEIN (GP130)[215 aa] | A | 33.3 /30.2 |
9 /9 |
IL6RB_HUMAN PROTEIN (GP130) | |
1bqu[1] | A | IL6RB_HUMAN PROTEIN (GP130)[208 aa] | B | 20.0 /29.9 |
10 /11 |
IL6RB_HUMAN PROTEIN (GP130) | |
8d7h[2] | F | CRLF1_HUMAN Cytokine receptor-like factor 1[303 aa] | C | 40.0 /29.6 |
5 /6 |
CRLF1_HUMAN Cytokine receptor-like factor 1 | |
3npz[2] | C | PRLR_RAT Prolactin receptor[199 aa] | B | 15.4 /25.7 |
13 /14 |
PRLR_RAT Prolactin receptor | |
3ew3[1] | C | PRLR_RAT Prolactin receptor[181 aa] | B | 10.0 /25.4 |
10 /11 |
PRLR_RAT Prolactin receptor | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
PRECIPITANT | |||||||
468 | pdb_id | contact mol | homologue | ||||
a3 | description | a4 | identity[%]5 | Ncon6 | description | ||
1bqu[3] | C |
SO4
SULFATE ION[5 atoms] |
A | 0.0 /30.2 |
4 /4 |
IL6RB_HUMAN PROTEIN (GP130) | |
1bqu[9] | E |
SO4
SULFATE ION[5 atoms] |
A | 100.0 /30.2 |
2 /2 |
IL6RB_HUMAN PROTEIN (GP130) | |
1bqu[1] | I |
SO4
SULFATE ION[5 atoms] |
B | 0.0 /29.9 |
2 /2 |
IL6RB_HUMAN PROTEIN (GP130) | |
1bqu[3] | J |
SO4
SULFATE ION[5 atoms] |
B | 0.0 /29.9 |
3 /3 |
IL6RB_HUMAN PROTEIN (GP130) | |
1n26[2] | F |
SO4
SULFATE ION[5 atoms] |
A | 100.0 /100.0 |
3 /3 |
IL6A_HUMAN IL-6 Receptor alpha chain | |
1n26[2] | G |
SO4
SULFATE ION[5 atoms] |
A | 100.0 /100.0 |
3 /3 |
IL6A_HUMAN IL-6 Receptor alpha chain | |
3l5h[1] | I |
SO4
SULFATE ION[5 atoms] |
A | 0.0 /28.8 |
1 /1 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
3l5h[1] | J |
SO4
SULFATE ION[5 atoms] |
A | 0.0 /28.8 |
1 /1 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
6o4p[1] | I |
SO4
SULFATE ION[5 atoms] |
A | 0.0 /35.0 |
1 /3 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
6o4p[2] | J |
SO4
SULFATE ION[5 atoms] |
A | 33.3 /35.0 |
3 /3 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
6o4p[1] | L |
SO4
SULFATE ION[5 atoms] |
B | 0.0 /35.4 |
2 /2 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
6o4p[1] | M |
SO4
SULFATE ION[5 atoms] |
B | 0.0 /35.4 |
3 /3 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
6o4p[1] | P |
SO4
SULFATE ION[5 atoms] |
B | 0.0 /35.4 |
1 /1 |
I11RA_HUMAN Interleukin-11 receptor subunit alpha | |
3d87[2] | E |
PO4
PHOSPHATE ION[5 atoms] |
B | 50.0 /28.8 |
2 /2 |
IL12B_HUMAN Interleukin-12 subunit p40 | |
8upa[1] | G |
PO4
PHOSPHATE ION[5 atoms] |
B | 0.0 /29.9 |
3 /4 |
IL6RB_HUMAN Interleukin-6 receptor subunit beta | |
5mj3[1] | G |
PGE
TRIETHYLENE GLYCOL[10 atoms] |
A | 75.0 /28.3 |
4 /4 |
IL12B_HUMAN Interleukin-12 subunit beta | |
1bqu[1] | F |
GOL
GLYCEROL[6 atoms] |
A | 50.0 /30.2 |
6 /6 |
IL6RB_HUMAN PROTEIN (GP130) | |
1bqu[2] | G |
GOL
GLYCEROL[6 atoms] |
A | 25.0 /30.2 |
8 /8 |
IL6RB_HUMAN PROTEIN (GP130) | |
1bqu[1] | L |
GOL
GLYCEROL[6 atoms] |
B | 50.0 /29.9 |
6 /6 |
IL6RB_HUMAN PROTEIN (GP130) | |
1bqu[1] | M |
GOL
GLYCEROL[6 atoms] |
B | 25.0 /29.9 |
4 /4 |
IL6RB_HUMAN PROTEIN (GP130) | |
4i18[1] | K |
GOL
GLYCEROL[6 atoms] |
E | 83.3 /24.9 |
6 /6 |
PRLR_HUMAN Prolactin receptor | |
4i18[1] | L |
ACT
ACETATE ION[4 atoms] |
E | 0.0 /24.9 |
2 /2 |
PRLR_HUMAN Prolactin receptor | |
3d48[1] | D |
CO3
CARBONATE ION[4 atoms] |
B | 50.0 /25.1 |
2 /2 |
PRLR_HUMAN Prolactin receptor | |
3d48[1] | E |
CO3
CARBONATE ION[4 atoms] |
B | 75.0 /25.1 |
4 /4 |
PRLR_HUMAN Prolactin receptor | |
3d48[1] | F |
CO3
CARBONATE ION[4 atoms] |
B | 12.5 /25.1 |
8 /8 |
PRLR_HUMAN Prolactin receptor | |
3ncc[1] | G |
CO3
CARBONATE ION[4 atoms] |
B | 0.0 /24.7 |
2 /2 |
PRLR_HUMAN Prolactin receptor | |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. |