[Multiple Alignment(many alignments)]
[Alignment Bar(many alignments)]
[show plain BLAST file]
BLASTP 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: unitmol_20240403.fasta
829,018 sequences; 237,935,689 total letters
Query= sp|P08887|IL6RA_HUMAN Interleukin-6 receptor subunit alpha OS=Homo
sapiens OX=9606 GN=IL6R PE=1 SV=1
Length=468
Score E
Sequences producing significant alignments: (Bits) Value
1n26_A A IL-6 Receptor alpha chain 624 0.0
8d82_A C Soluble interleukin-6 receptor subunit alpha 618 0.0
8d82_D G Soluble interleukin-6 receptor subunit alpha 618 0.0
1p9m_C C Interleukin-6 receptor alpha chain 424 3e-148
8qy6_C C Interleukin-6 receptor subunit alpha 424 3e-144
8qy5_E F Interleukin-6 receptor subunit alpha 424 3e-144
8qy5_C C Interleukin-6 receptor subunit alpha 424 3e-144
8qy6_E F Interleukin-6 receptor subunit alpha 424 3e-144
5fuc_C C INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, INTERLEUKIN-6 RECE... 414 7e-144
5fuc_D D INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, INTERLEUKIN-6 RECE... 409 6e-142
7dc8_C C Interleukin-6 receptor subunit alpha 389 2e-134
7dc8_F F Interleukin-6 receptor subunit alpha 384 2e-132
2arw_A A Interleukin-6 receptor alpha chain 221 5e-70
8iow_A I Interleukin-6 receptor subunit alpha 226 9e-69
8j6f_C I Interleukin-6 receptor subunit alpha 132 4e-33
8dpt_F F Interleukin-11 receptor subunit alpha 105 4e-24
8dpt_C C Interleukin-11 receptor subunit alpha 105 4e-24
6o4p_A A Interleukin-11 receptor subunit alpha 103 4e-23
6o4p_B B Interleukin-11 receptor subunit alpha 103 4e-23
8dpu_R R Interleukin-11 receptor subunit alpha 103 5e-23
8dpu_O O Interleukin-11 receptor subunit alpha 103 5e-23
8dpu_F F Interleukin-11 receptor subunit alpha 103 5e-23
8dpu_L L Interleukin-11 receptor subunit alpha 103 5e-23
8dpu_I I Interleukin-11 receptor subunit alpha 103 5e-23
8dpu_C C Interleukin-11 receptor subunit alpha 103 5e-23
8d7h_A C Ciliary neurotrophic factor receptor subunit alpha 99.0 2e-21
8d7e_A C Ciliary neurotrophic factor receptor subunit alpha 99.0 2e-21
8d7h_D G Ciliary neurotrophic factor receptor subunit alpha 99.0 2e-21
8d74_C C Ciliary neurotrophic factor receptor subunit alpha 86.3 3e-17
8d7r_B C Ciliary neurotrophic factor receptor subunit alpha 86.3 3e-17
1uc6_A A Ciliary Neurotrophic Factor Receptor alpha 69.7 3e-13
8dps_C C Interleukin-11 receptor subunit alpha 73.6 4e-13
8dps_F F Interleukin-11 receptor subunit alpha 73.6 4e-13
8qy4_F E Interleukin-11 receptor subunit alpha 72.4 2e-12
8qy4_E B Interleukin-11 receptor subunit alpha 72.4 2e-12
1f42_A A INTERLEUKIN-12 BETA CHAIN 60.8 7e-09
8d7h_F E Cytokine receptor-like factor 1 60.8 1e-08
8d7h_C A Cytokine receptor-like factor 1 60.8 1e-08
3duh_A A Interleukin-12 subunit beta 60.1 1e-08
5mzv_A A Interleukin-12 subunit beta 59.7 2e-08
6wdq_A A Interleukin-12 subunit beta 59.3 2e-08
8oe4_A A Interleukin-12 subunit beta 59.3 2e-08
3hmx_A A Interleukin-12 subunit beta 58.2 5e-08
3qwr_A A Interleukin-12 subunit beta 57.8 6e-08
4grw_B B Interleukin-12 subunit beta 58.2 6e-08
5mj3_A A Interleukin-12 subunit beta 57.8 7e-08
3d87_B B Interleukin-12 subunit p40 57.4 9e-08
3d87_D D Interleukin-12 subunit p40 57.0 1e-07
5mxa_B A Interleukin-12 subunit beta 55.8 4e-07
1bqu_B B PROTEIN (GP130) 53.9 5e-07
1pvh_C C Interleukin-6 receptor beta chain 53.9 5e-07
1pvh_A A Interleukin-6 receptor beta chain 53.9 5e-07
3l5h_A A Interleukin-6 receptor subunit beta 55.8 6e-07
1bqu_A A PROTEIN (GP130) 53.9 6e-07
8d82_F E Interleukin-6 receptor subunit beta 55.8 6e-07
8d82_C A Interleukin-6 receptor subunit beta 55.8 6e-07
1i1r_A A INTERLEUKIN-6 RECEPTOR BETA CHAIN 54.7 8e-07
3duh_B B Interleukin-12 subunit beta 54.7 8e-07
8dpu_P P Interleukin-6 receptor subunit beta 54.3 8e-07
8dpu_M M Interleukin-6 receptor subunit beta 54.3 8e-07
8dpu_G G Interleukin-6 receptor subunit beta 54.3 8e-07
8dpu_D D Interleukin-6 receptor subunit beta 54.3 8e-07
8dpu_J J Interleukin-6 receptor subunit beta 54.3 8e-07
8dpu_A A Interleukin-6 receptor subunit beta 54.3 8e-07
8dps_D D Interleukin-6 receptor subunit beta 54.3 9e-07
8dps_A A Interleukin-6 receptor subunit beta 54.3 9e-07
7u7n_B B Interleukin-6 receptor subunit beta 54.3 9e-07
1p9m_A A Interleukin-6 receptor beta chain 54.3 9e-07
8cr8_A A Interleukin-12 subunit beta 54.7 9e-07
8dpt_D D Interleukin-6 receptor subunit beta 55.1 1e-06
8dpt_A A Interleukin-6 receptor subunit beta 55.1 1e-06
5njd_E E Interleukin-12 subunit beta 53.9 1e-06
8d6a_B A Interleukin-6 receptor subunit beta 54.7 2e-06
8d7r_D A Interleukin-6 receptor subunit beta 54.7 2e-06
8d74_A A Interleukin-6 receptor subunit beta 54.7 2e-06
5njd_C C Interleukin-12 subunit beta 53.9 2e-06
8d85_D B Interleukin-6 receptor subunit beta 54.3 2e-06
4grw_D D Interleukin-12 subunit beta 53.5 2e-06
8qy6_F D Interleukin-6 receptor subunit beta 53.9 3e-06
8qy6_A A Interleukin-6 receptor subunit beta 53.9 3e-06
8qy5_F D Interleukin-6 receptor subunit beta 53.9 3e-06
8qy5_A A Interleukin-6 receptor subunit beta 53.9 3e-06
8qy4_B C Interleukin-6 receptor subunit beta 53.5 3e-06
8qy4_D F Interleukin-6 receptor subunit beta 53.5 3e-06
1f45_A A INTERLEUKIN-12 BETA CHAIN 52.8 3e-06
5njd_A A Interleukin-12 subunit beta 52.8 3e-06
5njd_I I Interleukin-12 subunit beta 52.8 4e-06
5mj4_A A Interleukin-12 subunit beta 52.4 4e-06
5njd_G G Interleukin-12 subunit beta 52.4 4e-06
5njd_K K Interleukin-12 subunit beta 52.4 4e-06
7z0l_A A Interleukin-6 receptor subunit beta 50.8 1e-05
3d85_D D Interleukin-12 subunit p40 50.4 2e-05
1bj8_A A GP130 46.6 3e-05
3ew3_B B Prolactin receptor 48.1 5e-05
3npz_B B Prolactin receptor 48.1 5e-05
3ncb_B B Prolactin receptor 46.6 1e-04
3n0p_B B Prolactin receptor 46.6 1e-04
3n06_B B Prolactin receptor 46.6 1e-04
3mzg_B B Prolactin receptor 46.6 1e-04
3npz_C C Prolactin receptor 46.6 2e-04
3nce_B B Prolactin receptor 45.8 3e-04
3ncc_B B Prolactin receptor 45.8 3e-04
3ncf_B B Prolactin receptor 45.8 3e-04
6uib_B B Interleukin-12 subunit beta 46.2 4e-04
3d48_B R Prolactin receptor 45.1 6e-04
4i18_E R Prolactin receptor 43.9 0.001
7u7n_C C Interleukin-27 subunit beta 43.9 0.001
8d85_A C Interleukin-27 subunit beta 43.9 0.001
1f6f_B B PROLACTIN RECEPTOR 43.5 0.001
8odz_D D Interleukin-12 receptor subunit beta-2,Calmodulin-1 44.7 0.002
8oe0_D D Interleukin-12 receptor subunit beta-2,Calmodulin-1 44.7 0.002
7z3p_B B Leptin receptor 43.1 0.002
8dha_B B Leptin receptor 43.1 0.006
4i18_F C Prolactin receptor 42.0 0.006
7zxk_B B Interleukin-27 subunit beta 42.0 0.006
7zxk_D D Interleukin-27 subunit beta 42.0 0.006
8b7q_B B Leptin receptor 43.1 0.007
6sff_A A Interleukin-12 subunit beta 42.4 0.007
7r3n_D D Interleukin-12 subunit beta 42.4 0.007
8pb1_B B Interleukin-12 subunit beta 42.4 0.007
8odz_B B Interleukin-12 subunit beta 42.4 0.007
7pur_A A Interleukin-12 subunit beta 42.4 0.008
6sp3_B B Interleukin-12 subunit beta 42.0 0.009
7r3n_B B Interleukin-12 subunit beta 42.0 0.009
6smc_B B Interleukin-12 subunit beta 42.0 0.010
6smc_A A Interleukin-12 subunit beta 42.0 0.010
6smc_C C Interleukin-12 subunit beta 42.0 0.010
7r3n_C C Interleukin-12 subunit beta 42.0 0.010
7r3n_A A Interleukin-12 subunit beta 42.0 0.010
8oe0_B B Interleukin-12 subunit beta 41.6 0.011
8cr5_A A Interleukin-12 subunit beta 42.0 0.011
6sp3_A A Interleukin-12 subunit beta 42.0 0.011
7pur_B B Interleukin-12 subunit beta 42.0 0.011
8dh8_A A Leptin receptor 42.0 0.013
8dh8_B B Leptin receptor 42.0 0.013
3ew3_C C Prolactin receptor 40.8 0.015
1bp3_B B PROTEIN (PROLACTIN RECEPTOR) 40.4 0.018
7z3r_B B Leptin receptor 40.8 0.020
8avd_F F Leptin receptor 41.6 0.020
8avd_D D Leptin receptor 41.6 0.020
8avd_B B Leptin receptor 41.6 0.020
8avb_B B Leptin receptor 41.6 0.020
8avb_C F Leptin receptor 41.6 0.020
8avc_F F Leptin receptor 41.6 0.020
8avc_D D Leptin receptor 41.6 0.020
8avc_B B Leptin receptor 41.6 0.020
8dh9_B B Leptin receptor 40.8 0.027
8dh9_A A Leptin receptor 40.8 0.029
2lfg_A A Prolactin receptor 37.0 0.091
6smc_D D Interleukin-12 subunit beta 38.5 0.13
8il3_A A Light chain 37.4 0.19
2djs_A A Ephrin type-B receptor 1 35.4 0.23
8ivw_F F Light chain of antibody 10V8 Fab fragment 36.2 0.40
8ivw_C C Light chain of antibody 10V8 Fab fragment 36.2 0.40
8ivw_L L Light chain of antibody 10V8 Fab fragment 36.2 0.40
8ivw_I I Light chain of antibody 10V8 Fab fragment 36.2 0.40
6ani_D L Coltuximab Fab light chain 36.2 0.45
6ani_F M Coltuximab Fab light chain 36.2 0.48
5uix_B L DH576 Fab light chain 36.2 0.51
4hs8_C L antibody hu5B3.v2 Fab light chain 35.8 0.60
2q76_C C Fab F10.6.6 fragment Light Chain 35.8 0.61
2q76_A A Fab F10.6.6 fragment Light Chain 35.8 0.61
1p2c_A A light chain anti-lysozyme antibody F10.6.6 35.8 0.61
8cr6_A A Interleukin-12 subunit beta 36.2 0.61
1p2c_D D light chain anti-lysozyme antibody F10.6.6 35.8 0.62
6pis_F M ANTIBODY FAB FRAGMENT LIGHT CHAIN 35.4 0.74
6pis_C L ANTIBODY FAB FRAGMENT LIGHT CHAIN 35.4 0.74
1x5l_A A Ephrin type-A receptor 8 33.9 1.0
5oj6_B B MAM domain-containing glycosylphosphatidylinositol ancho... 35.8 1.1
8cby_A L anti-cortisol (17) Fab (light chain) 34.7 1.3
8cbz_A L anti-cortisol (17) Fab (light chain) 34.7 1.3
8cbx_A L anti-cortisol (17) Fab (light chain) 34.7 1.3
8cc1_A L anti-cortisol (17) Fab (light chain) 34.7 1.3
8cc0_A L anti-cortisol (17) Fab (light chain) 34.7 1.3
6d9w_C L Fab Light Chain 34.7 1.4
5kte_C L Fab Light Chain 34.7 1.4
8hpk_C L Fab fragment Light chain 34.7 1.5
1mlb_A A IGG1-KAPPA D44.1 FAB (LIGHT CHAIN) 34.7 1.5
1mlc_C C IGG1-KAPPA D44.1 FAB (LIGHT CHAIN) 34.7 1.5
1mlc_A A IGG1-KAPPA D44.1 FAB (LIGHT CHAIN) 34.7 1.5
5u8q_D L Fv 24-60 light chain 33.1 1.5
7ut3_B L G10C Light chain 34.7 1.6
5u8r_C L Fv 24-60 light chain 33.1 1.6
8gy5_B B light chain 34.3 1.8
8gy5_E L light chain 34.3 1.8
5oj2_A A MAM domain-containing glycosylphosphatidylinositol ancho... 35.0 1.8
6x7w_E C antibody vFP49.02 light chain 34.3 1.9
6x7w_D L antibody vFP49.02 light chain 34.3 1.9
7z3q_B B Leptin receptor 34.3 1.9
7z3q_D D Leptin receptor 34.3 2.1
1v7m_D M Monoclonal TN1 Fab Light Chain 33.9 2.3
1v7n_E N Monoclonal TN1 Fab Light Chain 33.9 2.3
1v7n_C M Monoclonal TN1 Fab Light Chain 33.9 2.3
1v7m_A L Monoclonal TN1 Fab Light Chain 33.9 2.3
5oj2_B B MAM domain-containing glycosylphosphatidylinositol ancho... 34.7 2.4
2a0l_C C 33H1 Fv fragment 32.3 2.5
2a0l_E E 33H1 Fv fragment 32.3 2.5
1dqq_C C ANTI-LYSOZYME ANTIBODY HYHEL-63 (LIGHT CHAIN) 33.9 2.5
1dqm_A L ANTI-LYSOZYME ANTIBODY HYHEL-63 (LIGHT CHAIN) 33.9 2.5
1nby_A A antibody kappa light chain 33.9 2.5
1ndm_A A antibody kappa light chain 33.9 2.5
1dqq_A A ANTI-LYSOZYME ANTIBODY HYHEL-63 (LIGHT CHAIN) 33.9 2.5
1dqj_A A ANTI-LYSOZYME ANTIBODY HYHEL-63 (LIGHT CHAIN) 33.9 2.5
1ndg_A A antibody kappa light chain 33.9 2.5
1nbz_A A antibody kappa light chain 33.9 2.5
1xgu_A A antibody kappa light chain 33.9 2.5
2zkh_A L Monoclonal TN1 FAB light chain 33.9 2.5
1cd9_B B PROTEIN (G-CSF RECEPTOR) 33.9 2.6
6gc2_A L Light Chain 34.3 2.6
1xgr_A A antibody kappa light chain 33.9 2.6
1xgp_A A antibody kappa light chain 33.9 2.6
1xgq_A A antibody kappa light chain 33.9 2.6
1xgt_A A antibody kappa light chain 33.9 2.6
1v7n_A L Monoclonal TN1 Fab Light Chain 33.9 2.7
1v7n_G O Monoclonal TN1 Fab Light Chain 33.9 2.7
6df0_A L 4G10-4D5 Antibody Light chain 33.9 2.8
7wvm_E D Light Chain of Cemiplimab 32.3 2.8
7wvm_B B Light Chain of Cemiplimab 32.3 2.8
7z3q_F F Leptin receptor 33.9 2.8
8g9y_F L vFP49.02 light chain 33.9 2.9
8g9x_F L vFP49.02 light chain 33.9 2.9
8g9w_F L vFP49.02 light chain 33.9 2.9
8eq6_B L Antibody FAB light chain 33.5 3.0
6df1_A L Anti-phosphotyrosine antibody 4G10-4D5 heavy chain 33.9 3.0
6v4p_D D Abciximab, light chain 33.5 3.3
35c8_A L IGG 5C8 33.5 3.5
25c8_A L IGG 5C8 33.5 3.5
15c8_A L IGG 5C8 FAB (LIGHT CHAIN) 33.5 3.6
4ffv_C C 11A19 Fab light chain 33.5 3.7
4ffv_E L 11A19 Fab light chain 33.5 3.7
1bm3_A L IMMUNOGLOBULIN OPG2 FAB, CONSTANT DOMAIN 33.5 3.8
1opg_A L OPG2 FAB (LIGHT CHAIN) 33.5 3.8
6u6u_B L BI00655130 Fab light chain 33.5 3.9
6djp_D D 8B8 light chain Fab 33.1 4.3
5opy_B L Light chain of LM609 Fab (antigen-binding fragment) 33.1 4.3
1ors_A A 33H1 Fab light chain 33.1 4.3
6avu_D L Fab LM609 light chain 33.1 4.4
6avr_D L Fab LM609 light chain 33.1 4.4
6avq_D L LM609 Fab light chain 33.1 4.4
2brr_B L MN20B9.34 ANTI-P1.4 ANTIBODY, FAB LIGHT CHAIN 33.1 4.5
6k7o_C C h128-3 Fab light chain 33.1 4.5
6k7o_I L h128-3 Fab light chain 33.1 4.5
6k7o_E E h128-3 Fab light chain 33.1 4.5
6k7o_G G h128-3 Fab light chain 33.1 4.5
2brr_D X MN20B9.34 ANTI-P1.4 ANTIBODY, FAB LIGHT CHAIN 33.1 4.6
8dua_H E ITS92.02 Light Chain 33.1 4.7
8dua_L K ITS92.02 Light Chain 33.1 4.7
8dua_D L ITS92.02 Light Chain 33.1 4.7
7rah_C C M2B10 Fab Light Chain 32.7 5.4
5gir_B L Light chain of Fab fragment 33.1 5.5
5gir_D B Light chain of Fab fragment 33.1 5.6
5gis_B L Light chain of Fab fragment 33.1 5.6
3iu3_F L Light chain of Fab fragment of Basiliximab 32.7 5.6
3iu3_B B Light chain of Fab fragment of Basiliximab 32.7 5.6
6vvu_F F Fab E104.v1 light chain 32.7 5.6
6vvu_I I Fab E104.v1 light chain 32.7 5.6
7shz_E L HAE Variable fragment Light chain 32.0 5.7
7shz_G J HAE Variable fragment Light chain 32.0 5.7
1rvf_E L FAB 17-IA 31.6 5.7
6vvu_L L Fab E104.v1 light chain 32.7 5.8
1mim_A L CHIMERIC SDZ CHI621 32.7 5.9
1fnl_A A LOW AFFINITY IMMUNOGLOBULIN GAMMA FC REGION RECEPTOR III-B 32.3 5.9
6df2_D A Anti-phosphotyrosine antibody c310-4D5 heavy chain 33.1 6.0
6df2_A L Anti-phosphotyrosine antibody c310-4D5 heavy chain 33.1 6.0
6vvu_K K Fab E104.v1 light chain 32.7 6.0
7cw3_TA p Fab light chain 32.7 6.1
7cw3_GA n Fab light chain 32.7 6.1
7cw3_W l Fab light chain 32.7 6.1
7cw3_J r Fab light chain 32.7 6.1
7cw2_V V Fab light chain 32.7 6.1
7cw2_K T Fab light chain 32.7 6.1
7cw0_M R Fab light chain 32.7 6.1
7cw0_E P Fab light chain 32.7 6.1
7cvz_M R Fab light chain 32.7 6.1
7cvz_E P Fab light chain 32.7 6.1
5nj6_C L Fab3949 L 32.7 6.2
1orq_A A 6E1 Fab light chain 32.7 6.3
3w2d_B L Monoclonal Antibody 3E2 Fab figment light chain 32.7 6.5
3iu3_D D Light chain of Fab fragment of Basiliximab 32.7 6.6
1pgr_F F PROTEIN (G-CSF RECEPTOR) 32.7 6.7
1ken_G L influenza virus infectivity neutralizing antibody (light... 32.7 6.7
1ken_I U influenza virus infectivity neutralizing antibody (light... 32.7 6.7
8iv8_D D light chain of 1C4 31.2 6.8
8iv5_D B light chain of 1C4 31.2 6.8
7shz_L F HAE Variable fragment Light chain 32.0 6.8
7shz_F D HAE Variable fragment Light chain 32.0 6.8
1t89_C C Low affinity immunoglobulin gamma Fc region receptor III-B 32.3 6.9
1t83_C C Low affinity immunoglobulin gamma Fc region receptor III-B 32.3 6.9
1e4k_C C LOW AFFINITY IMMUNOGLOBULIN GAMMA FC RECEPTOR III 32.3 6.9
1e4j_A A LOW AFFINITY IMMUNOGLOBULIN GAMMA FC RECEPTOR III 32.3 7.0
5yc5_C C Low affinity immunoglobulin gamma Fc region receptor III-A 32.3 7.0
1x5h_A A Neogenin 31.6 7.5
5mn2_B B Low affinity immunoglobulin gamma Fc region receptor III-A 32.0 7.8
7w71_D L Light chain of Fab 32.3 8.1
6ada_D D antibody Fab fragment, light chain 32.3 8.2
2r9h_D D Fab fragment 32.3 8.2
6adc_F F antibody Fab fragment, light chain 32.3 8.2
5hd8_D D FAB FRAGMENT (LIGHT CHAIN) 32.3 8.2
4kk5_D D Fab, light chain 32.3 8.2
3det_D D Fab fragment, Light chain 32.3 8.2
7cvt_F F antibody Fab fragment light chain 32.3 8.2
6adc_D D antibody Fab fragment, light chain 32.3 8.2
5hd8_F F FAB FRAGMENT (LIGHT CHAIN) 32.3 8.2
4mqx_D D ERIC 32.3 8.2
4lou_F F Fab light chain 32.3 8.2
4kka_D D Fab, light chain 32.3 8.2
4kjp_F F light chain of Fab fragment 32.3 8.2
3det_F F Fab fragment, Light chain 32.3 8.2
6ada_F F antibody Fab fragment, light chain 32.3 8.2
6adb_D D antibody Fab fragment, light chain 32.3 8.2
6adb_F F antibody Fab fragment, light chain 32.3 8.2
6ad7_D D antibody Fab fragment light chain 32.3 8.2
6ad8_D D antibody Fab fragment light chain 32.3 8.2
6ad7_F F antibody Fab fragment light chain 32.3 8.2
6ad8_F F antibody Fab fragment light chain 32.3 8.2
4lou_D D Fab light chain 32.3 8.2
2r9h_F F Fab fragment 32.3 8.2
7cvt_D D antibody Fab fragment light chain 32.3 8.2
7cvs_D D antibody Fab fragment light chain 32.3 8.2
7cvs_F F antibody Fab fragment light chain 32.3 8.2
4fg6_F F Fab fragment (Light chain) 32.3 8.2
4fg6_D D Fab fragment (Light chain) 32.3 8.2
2fee_D O Fab fragment, light chain 32.3 8.2
2fee_F L Fab fragment, light chain 32.3 8.2
2fed_D D Fab fragment, light chain 32.3 8.2
2fed_F F Fab fragment, light chain 32.3 8.2
2fec_F L Fab fragment, light chain 32.3 8.2
2fec_D O Fab fragment, light chain 32.3 8.2
4kjp_D D light chain of Fab fragment 32.3 8.2
2ht2_D D Fab fragment, light chain 32.3 8.2
4kk8_D D Fab, light chain 32.3 8.2
2htl_D D Fab fragment, Light chain 32.3 8.2
2htl_F F Fab fragment, Light chain 32.3 8.2
2htk_D D Fab fragment, Light chain 32.3 8.2
2htk_F F Fab fragment, Light chain 32.3 8.2
2ht2_F F Fab fragment, light chain 32.3 8.2
2ht3_D D Fab fragment, Light chain 32.3 8.2
2ht4_D D Fab fragment, Light chain 32.3 8.2
2ht3_F F Fab fragment, Light chain 32.3 8.2
2ht4_F F Fab fragment, Light chain 32.3 8.2
2ez0_F F Fab Fragment (Light Chain) 32.3 8.2
2ez0_D D Fab Fragment (Light Chain) 32.3 8.2
2exy_F F Fab Fragment (Light Chain) 32.3 8.2
2exw_F F Fab Fragment (Light Chain) 32.3 8.2
2exy_D D Fab Fragment (Light Chain) 32.3 8.2
2exw_D D Fab Fragment (Light Chain) 32.3 8.2
4kkl_D D Fab, light chain 32.3 8.2
4kkl_F F Fab, light chain 32.3 8.2
4kkc_D D Fab, light chain 32.3 8.2
4kkb_F F Fab, light chain 32.3 8.2
4kkb_D D Fab, light chain 32.3 8.2
4kkc_F F Fab, light chain 32.3 8.2
4kka_F F Fab, light chain 32.3 8.2
4kk8_F F Fab, light chain 32.3 8.2
4kk9_D D Fab, light chain 32.3 8.2
4kk9_F F Fab, light chain 32.3 8.2
4kk5_F F Fab, light chain 32.3 8.2
4kk6_F F Fab, light chain 32.3 8.2
4kk6_D D Fab, light chain 32.3 8.2
4kjw_F F Fab, light chain 32.3 8.2
4kjw_D D Fab, light chain 32.3 8.2
4kjq_F F Fab, light chain 32.3 8.2
4kjq_D D Fab, light chain 32.3 8.2
6k5i_D D Fab fragment, light chain 32.3 8.2
6k5a_D D Fab fragment, light chain 32.3 8.2
3ejy_D D Fab fragment, Light chain 32.3 8.2
2hlf_D D Fab Fragment, Light chain 32.3 8.2
6k5f_D D Fab fragment, light chain 32.3 8.2
1ots_D D Fab fragment (light chain) 32.3 8.2
1otu_F F Fab fragment (Light chain) 32.3 8.2
2hlf_F F Fab Fragment, Light chain 32.3 8.2
4ene_D D light chain of Fab fragment 32.3 8.2
4ene_F F light chain of Fab fragment 32.3 8.2
3ejz_D D Fab fragment, Light chain 32.3 8.2
3ejz_F F Fab fragment, Light chain 32.3 8.2
3ejy_F F Fab fragment, Light chain 32.3 8.2
6k5i_F F Fab fragment, light chain 32.3 8.2
6k5f_F F Fab fragment, light chain 32.3 8.2
6k5d_F F Fab fragment, light chain 32.3 8.2
6k5d_D D Fab fragment, light chain 32.3 8.2
6k5a_F F Fab fragment, light chain 32.3 8.2
4mqx_F F ERIC 32.3 8.2
2h2s_F F FAB fragment, light chain 32.3 8.2
2h2s_D D FAB fragment, light chain 32.3 8.2
2h2p_D D FAB fragment, light chain 32.3 8.2
2h2p_F F FAB fragment, light chain 32.3 8.2
1otu_D D Fab fragment (Light chain) 32.3 8.2
1ott_F F Fab fragment (Light chain) 32.3 8.2
1ott_D D Fab fragment (Light chain) 32.3 8.2
1ots_F F Fab fragment (light chain) 32.3 8.2
7w71_F M Light chain of Fab 32.3 8.3
2iff_A L IGG1 HYHEL-5 FAB (LIGHT CHAIN) 32.3 8.6
1bql_A L HYHEL-5 FAB (LIGHT CHAIN) 32.3 8.6
8iow_B D2 Interleukin-6 receptor subunit alpha 32.7 8.7
1yqv_A L HyHEL-5 Antibody Light Chain 32.3 8.7
7x3y_B L 9A3 light chain 31.2 8.7
7x4k_B L 9A3 light chain 31.2 8.7
7x3d_F L 9A3 light chain 31.2 8.7
7x3f_B L 9A3 light chain 31.2 8.7
7x3e_F L 9A3 light chain 31.2 8.7
1pgr_B B PROTEIN (G-CSF RECEPTOR) 32.3 8.8
8ghp_C L anti-GUCY2C-scFv antibody light chain 31.2 8.8
6m87_F I Fab 10A6 light chain 32.3 9.3
1gl4_B B BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN ... 30.8 9.4
6m87_E G Fab 10A6 light chain 32.0 9.5
6m87_C C Fab 10A6 light chain 32.0 9.5
6m87_G K Fab 10A6 light chain 32.0 9.8
7kq7_C B Interleukin-21 receptor 32.0 9.9
>1n26_A A IL-6 Receptor alpha chain
Length=325
Score = 624 bits (1609), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 299/299 (100%), Positives = 299/299 (100%), Gaps = 0/299 (0%)
Query 20 LAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGR 79
LAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGR
Sbjct 1 LAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGR 60
Query 80 RLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRST 139
RLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRST
Sbjct 61 RLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRST 120
Query 140 PSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCVASSVG 199
PSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCVASSVG
Sbjct 121 PSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCVASSVG 180
Query 200 SKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRA 259
SKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRA
Sbjct 181 SKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRA 240
Query 260 ERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTES 318
ERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTES
Sbjct 241 ERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTES 299
>8d82_A C Soluble interleukin-6 receptor subunit alpha
Length=346
Score = 618 bits (1594), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 296/296 (100%), Positives = 296/296 (100%), Gaps = 0/296 (0%)
Query 23 RRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLL 82
RRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLL
Sbjct 4 RRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLL 63
Query 83 LRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSL 142
LRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSL
Sbjct 64 LRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSL 123
Query 143 TTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCVASSVGSKF 202
TTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCVASSVGSKF
Sbjct 124 TTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCVASSVGSKF 183
Query 203 SKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERS 262
SKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERS
Sbjct 184 SKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERS 243
Query 263 KTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTES 318
KTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTES
Sbjct 244 KTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTES 299
>8d82_D G Soluble interleukin-6 receptor subunit alpha
Length=346
Score = 618 bits (1594), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 296/296 (100%), Positives = 296/296 (100%), Gaps = 0/296 (0%)
Query 23 RRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLL 82
RRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLL
Sbjct 4 RRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLL 63
Query 83 LRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSL 142
LRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSL
Sbjct 64 LRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSL 123
Query 143 TTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCVASSVGSKF 202
TTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCVASSVGSKF
Sbjct 124 TTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCVASSVGSKF 183
Query 203 SKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERS 262
SKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERS
Sbjct 184 SKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERS 243
Query 263 KTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTES 318
KTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTES
Sbjct 244 KTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTES 299
>1p9m_C C Interleukin-6 receptor alpha chain
Length=201
Score = 424 bits (1089), Expect = 3e-148, Method: Compositional matrix adjust.
Identities = 201/201 (100%), Positives = 201/201 (100%), Gaps = 0/201 (0%)
Query 115 EEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKF 174
EEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKF
Sbjct 1 EEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKF 60
Query 175 SCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWL 234
SCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWL
Sbjct 61 SCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWL 120
Query 235 SVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRA 294
SVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRA
Sbjct 121 SVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRA 180
Query 295 QEEFGQGEWSEWSPEAMGTPW 315
QEEFGQGEWSEWSPEAMGTPW
Sbjct 181 QEEFGQGEWSEWSPEAMGTPW 201
>8qy6_C C Interleukin-6 receptor subunit alpha
Length=468
Score = 424 bits (1089), Expect = 3e-144, Method: Compositional matrix adjust.
Identities = 201/201 (100%), Positives = 201/201 (100%), Gaps = 0/201 (0%)
Query 115 EEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKF 174
EEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKF
Sbjct 115 EEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKF 174
Query 175 SCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWL 234
SCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWL
Sbjct 175 SCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWL 234
Query 235 SVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRA 294
SVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRA
Sbjct 235 SVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRA 294
Query 295 QEEFGQGEWSEWSPEAMGTPW 315
QEEFGQGEWSEWSPEAMGTPW
Sbjct 295 QEEFGQGEWSEWSPEAMGTPW 315
>8qy5_E F Interleukin-6 receptor subunit alpha
Length=468
Score = 424 bits (1089), Expect = 3e-144, Method: Compositional matrix adjust.
Identities = 201/201 (100%), Positives = 201/201 (100%), Gaps = 0/201 (0%)
Query 115 EEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKF 174
EEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKF
Sbjct 115 EEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKF 174
Query 175 SCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWL 234
SCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWL
Sbjct 175 SCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWL 234
Query 235 SVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRA 294
SVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRA
Sbjct 235 SVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRA 294
Query 295 QEEFGQGEWSEWSPEAMGTPW 315
QEEFGQGEWSEWSPEAMGTPW
Sbjct 295 QEEFGQGEWSEWSPEAMGTPW 315
>8qy5_C C Interleukin-6 receptor subunit alpha
Length=468
Score = 424 bits (1089), Expect = 3e-144, Method: Compositional matrix adjust.
Identities = 201/201 (100%), Positives = 201/201 (100%), Gaps = 0/201 (0%)
Query 115 EEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKF 174
EEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKF
Sbjct 115 EEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKF 174
Query 175 SCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWL 234
SCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWL
Sbjct 175 SCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWL 234
Query 235 SVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRA 294
SVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRA
Sbjct 235 SVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRA 294
Query 295 QEEFGQGEWSEWSPEAMGTPW 315
QEEFGQGEWSEWSPEAMGTPW
Sbjct 295 QEEFGQGEWSEWSPEAMGTPW 315
>8qy6_E F Interleukin-6 receptor subunit alpha
Length=468
Score = 424 bits (1089), Expect = 3e-144, Method: Compositional matrix adjust.
Identities = 201/201 (100%), Positives = 201/201 (100%), Gaps = 0/201 (0%)
Query 115 EEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKF 174
EEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKF
Sbjct 115 EEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKF 174
Query 175 SCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWL 234
SCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWL
Sbjct 175 SCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWL 234
Query 235 SVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRA 294
SVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRA
Sbjct 235 SVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRA 294
Query 295 QEEFGQGEWSEWSPEAMGTPW 315
QEEFGQGEWSEWSPEAMGTPW
Sbjct 295 QEEFGQGEWSEWSPEAMGTPW 315
>5fuc_C C INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, INTERLEUKIN-6
RECEPTOR
Length=231
Score = 414 bits (1063), Expect = 7e-144, Method: Compositional matrix adjust.
Identities = 197/200 (99%), Positives = 197/200 (99%), Gaps = 0/200 (0%)
Query 117 PQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSC 176
PQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNS AEDFQEPCQYSQESQKFSC
Sbjct 26 PQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSXAEDFQEPCQYSQESQKFSC 85
Query 177 QLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSV 236
QLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQG GILQPDPPANITVTAVARNPRWLSV
Sbjct 86 QLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGAGILQPDPPANITVTAVARNPRWLSV 145
Query 237 TWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQE 296
TWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHH VIHDAWSGLRHVVQLRAQE
Sbjct 146 TWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHAVIHDAWSGLRHVVQLRAQE 205
Query 297 EFGQGEWSEWSPEAMGTPWT 316
EFGQGEWSEWSPEAMGTPWT
Sbjct 206 EFGQGEWSEWSPEAMGTPWT 225
>5fuc_D D INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, INTERLEUKIN-6
RECEPTOR
Length=231
Score = 409 bits (1051), Expect = 6e-142, Method: Compositional matrix adjust.
Identities = 196/205 (96%), Positives = 196/205 (96%), Gaps = 0/205 (0%)
Query 113 PPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQ 172
PPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRK DFQEPCQYSQESQ
Sbjct 22 PPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKXXXXXXXDFQEPCQYSQESQ 81
Query 173 KFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPR 232
KFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQG GILQPDPPANITVTAVARNPR
Sbjct 82 KFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGAGILQPDPPANITVTAVARNPR 141
Query 233 WLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQL 292
WLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHH VIHDAWSGLRHVVQL
Sbjct 142 WLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHAVIHDAWSGLRHVVQL 201
Query 293 RAQEEFGQGEWSEWSPEAMGTPWTE 317
RAQEEFGQGEWSEWSPEAMGTPWTE
Sbjct 202 RAQEEFGQGEWSEWSPEAMGTPWTE 226
>7dc8_C C Interleukin-6 receptor subunit alpha
Length=218
Score = 389 bits (999), Expect = 2e-134, Method: Compositional matrix adjust.
Identities = 185/200 (93%), Positives = 185/200 (93%), Gaps = 0/200 (0%)
Query 117 PQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSC 176
PQLSCFRKSPLSNVVCEWG TKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSC
Sbjct 7 PQLSCFRKSPLSNVVCEWGXXXXXXXXTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSC 66
Query 177 QLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSV 236
QLAVPEGDSSFYIVSM V KFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSV
Sbjct 67 QLAVPEGDSSFYIVSMSVXXXXXXKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSV 126
Query 237 TWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQE 296
TWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQE
Sbjct 127 TWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQE 186
Query 297 EFGQGEWSEWSPEAMGTPWT 316
EFGQGEWSEWSPEAMGTPWT
Sbjct 187 EFGQGEWSEWSPEAMGTPWT 206
>7dc8_F F Interleukin-6 receptor subunit alpha
Length=218
Score = 384 bits (986), Expect = 2e-132, Method: Compositional matrix adjust.
Identities = 183/200 (92%), Positives = 183/200 (92%), Gaps = 0/200 (0%)
Query 117 PQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSC 176
PQLSCFRKSPLSNVVCEW AVLLVRKFQNSPAEDFQEPCQYSQESQKFSC
Sbjct 7 PQLSCFRKSPLSNVVCEWXXXXXXXXXXXAVLLVRKFQNSPAEDFQEPCQYSQESQKFSC 66
Query 177 QLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSV 236
QLAVPEGDSSFYIVSM VA KFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSV
Sbjct 67 QLAVPEGDSSFYIVSMSVAXXXXXKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSV 126
Query 237 TWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQE 296
TWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQE
Sbjct 127 TWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQE 186
Query 297 EFGQGEWSEWSPEAMGTPWT 316
EFGQGEWSEWSPEAMGTPWT
Sbjct 187 EFGQGEWSEWSPEAMGTPWT 206
>2arw_A A Interleukin-6 receptor alpha chain
Length=126
Score = 221 bits (563), Expect = 5e-70, Method: Compositional matrix adjust.
Identities = 102/102 (100%), Positives = 102/102 (100%), Gaps = 0/102 (0%)
Query 212 GILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVK 271
GILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVK
Sbjct 2 GILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVK 61
Query 272 DLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGT 313
DLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGT
Sbjct 62 DLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGT 103
>8iow_A I Interleukin-6 receptor subunit alpha
Length=365
Score = 226 bits (577), Expect = 9e-69, Method: Compositional matrix adjust.
Identities = 104/104 (100%), Positives = 104/104 (100%), Gaps = 0/104 (0%)
Query 209 QGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTW 268
QGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTW
Sbjct 209 QGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTW 268
Query 269 MVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMG 312
MVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMG
Sbjct 269 MVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMG 312
>8j6f_C I Interleukin-6 receptor subunit alpha
Length=365
Score = 132 bits (331), Expect = 4e-33, Method: Compositional matrix adjust.
Identities = 66/95 (69%), Positives = 66/95 (69%), Gaps = 0/95 (0%)
Query 215 QPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQ 274
QPDPPANITV VTWQDPHSWNSSFYRLRFELRYRA TWMVKDLQ
Sbjct 215 QPDPPANITVXXXXXXXXXXXVTWQDPHSWNSSFYRLRFELRYRAXXXXXXXTWMVKDLQ 274
Query 275 HHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPE 309
HH HVVQLRAQEEFGQGEWSEWSPE
Sbjct 275 HHXXXXXXXXXXXHVVQLRAQEEFGQGEWSEWSPE 309
>8dpt_F F Interleukin-11 receptor subunit alpha
Length=298
Score = 105 bits (262), Expect = 4e-24, Method: Compositional matrix adjust.
Identities = 95/302 (31%), Positives = 131/302 (43%), Gaps = 24/302 (8%)
Query 25 CPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLR-KPAAGSHPSRWAGMGRRLLL 83
CP GV PG SV L CPGV D V W +P P +G+G L+L
Sbjct 5 CPQAWGPPGVQYGQPGRSVKLCCPGVTAGD--PVSWFRDGEPKLLQGPD--SGLGHELVL 60
Query 84 RSVQLHDSGNYSCYRA-GRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSL 142
D G Y C G GTV L + PP P +SC + + N C W P L
Sbjct 61 AQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC-QAADYENFSCTWSPSQISGL 119
Query 143 TTKAVLLVRKFQNSPAEDFQE-------PCQYSQESQKFSCQLAVPEGDS--SFYIVSMC 193
T+ + RK A+ + PC V G S Y +++
Sbjct 120 PTRYLTSYRKKTVLGADSQRRSPSTGPWPC----PQDPLGAARCVVHGAEFWSQYRINVT 175
Query 194 VASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSS-FYRLR 252
+ +G+ ++ IL+PDPP + V +V PR L +W P SW S + L+
Sbjct 176 EVNPLGAS-TRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASWPSQPHFLLK 234
Query 253 FELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMG 312
F L+YR + ++T L+ VI DA +GL H V++ A++ G WS WSPEA G
Sbjct 235 FRLQYRPAQHPAWSTVEPAGLEE--VITDAVAGLPHAVRVSARDFLDAGTWSTWSPEAWG 292
Query 313 TP 314
TP
Sbjct 293 TP 294
>8dpt_C C Interleukin-11 receptor subunit alpha
Length=298
Score = 105 bits (262), Expect = 4e-24, Method: Compositional matrix adjust.
Identities = 95/302 (31%), Positives = 131/302 (43%), Gaps = 24/302 (8%)
Query 25 CPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLR-KPAAGSHPSRWAGMGRRLLL 83
CP GV PG SV L CPGV D V W +P P +G+G L+L
Sbjct 5 CPQAWGPPGVQYGQPGRSVKLCCPGVTAGD--PVSWFRDGEPKLLQGPD--SGLGHELVL 60
Query 84 RSVQLHDSGNYSCYRA-GRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSL 142
D G Y C G GTV L + PP P +SC + + N C W P L
Sbjct 61 AQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC-QAADYENFSCTWSPSQISGL 119
Query 143 TTKAVLLVRKFQNSPAEDFQE-------PCQYSQESQKFSCQLAVPEGDS--SFYIVSMC 193
T+ + RK A+ + PC V G S Y +++
Sbjct 120 PTRYLTSYRKKTVLGADSQRRSPSTGPWPC----PQDPLGAARCVVHGAEFWSQYRINVT 175
Query 194 VASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSS-FYRLR 252
+ +G+ ++ IL+PDPP + V +V PR L +W P SW S + L+
Sbjct 176 EVNPLGAS-TRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASWPSQPHFLLK 234
Query 253 FELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMG 312
F L+YR + ++T L+ VI DA +GL H V++ A++ G WS WSPEA G
Sbjct 235 FRLQYRPAQHPAWSTVEPAGLEE--VITDAVAGLPHAVRVSARDFLDAGTWSTWSPEAWG 292
Query 313 TP 314
TP
Sbjct 293 TP 294
>6o4p_A A Interleukin-11 receptor subunit alpha
Length=349
Score = 103 bits (258), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 96/303 (32%), Positives = 131/303 (43%), Gaps = 26/303 (9%)
Query 25 CPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLR-KPAAGSHPSRWAGMGRRLLL 83
CP GV PG SV L CPGV D V W +P P +G+G L+L
Sbjct 4 CPQAWGPPGVQYGQPGRSVKLCCPGVTAGD--PVSWFRDGEPKLLQGPD--SGLGHELVL 59
Query 84 RSVQLHDSGNYSCYRA-GRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSL 142
D G Y C G GTV L + PP P +SC + + N C W P L
Sbjct 60 AQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC-QAADYENFSCTWSPSQISGL 118
Query 143 TTKAVLLVRK--------FQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDS--SFYIVSM 192
T+ + RK SP+ PC V G S Y +++
Sbjct 119 PTRYLTSYRKKTVXXXXXXXXSPSTG-PWPC----PQDPLGAARCVVHGAEFWSQYRINV 173
Query 193 CVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSS-FYRL 251
+ +G+ ++ IL+PDPP + V +V PR L +W P SW S + L
Sbjct 174 TEVNPLGAS-TRLLDVSLQSILRPDPPQGLRVESVPGYPRRLRASWTYPASWPSQPHFLL 232
Query 252 RFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAM 311
+F L+YR + ++T L+ VI DA +GL H V++ A++ G WS WSPEA
Sbjct 233 KFRLQYRPAQHPAWSTVEPAGLEE--VITDAVAGLPHAVRVSARDFLDAGTWSTWSPEAW 290
Query 312 GTP 314
GTP
Sbjct 291 GTP 293
>6o4p_B B Interleukin-11 receptor subunit alpha
Length=349
Score = 103 bits (257), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 97/305 (32%), Positives = 129/305 (42%), Gaps = 30/305 (10%)
Query 25 CPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLR-KPAAGSHPSRWAGMGRRLLL 83
CP GV PG SV L CPGV D V W +P P +G+G L+L
Sbjct 4 CPQAWGPPGVQYGQPGRSVKLCCPGVTAGD--PVSWFRDGEPKLLQGPD--SGLGHELVL 59
Query 84 RSVQLHDSGNYSCYRA-GRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSL 142
D G Y C G GTV L + PP P +SC + + N C W P L
Sbjct 60 AQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC-QAADYENFSCTWSPSQISGL 118
Query 143 TTKAVLLVRK------------FQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIV 190
T+ + RK P Q+P ++ C + E S + I
Sbjct 119 PTRYLTSYRKKTVXXXXXXXXXXSTGPWPCPQDPLGAAR------CVVHGAEFWSQYRIN 172
Query 191 SMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSS-FY 249
V S + Q IL+PDPP + V +V PR L +W P SW S +
Sbjct 173 VTEVNPLGASTRLLDVSLQS--ILRPDPPQGLRVESVPGYPRRLRASWTYPASWPSQPHF 230
Query 250 RLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPE 309
L+F L+YR + ++T L+ VI DA +GL H V++ A++ G WS WSPE
Sbjct 231 LLKFRLQYRPAQHPAWSTVEPAGLEE--VITDAVAGLPHAVRVSARDFLDAGTWSTWSPE 288
Query 310 AMGTP 314
A GTP
Sbjct 289 AWGTP 293
>8dpu_R R Interleukin-11 receptor subunit alpha
Length=348
Score = 103 bits (256), Expect = 5e-23, Method: Compositional matrix adjust.
Identities = 97/305 (32%), Positives = 129/305 (42%), Gaps = 30/305 (10%)
Query 25 CPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLR-KPAAGSHPSRWAGMGRRLLL 83
CP GV PG SV L CPGV D V W +P P +G+G L+L
Sbjct 4 CPQAWGPPGVQYGQPGRSVKLCCPGVTAGD--PVSWFRDGEPKLLQGPD--SGLGHELVL 59
Query 84 RSVQLHDSGNYSCYRA-GRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSL 142
D G Y C G GTV L + PP P +SC + + N C W P L
Sbjct 60 AQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC-QAADYENFSCTWSPSQISGL 118
Query 143 TTKAVLLVRKF------------QNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIV 190
T+ + RK P Q+P ++ C + E S + I
Sbjct 119 PTRYLTSYRKKTVXXXXXXXXXPSTGPWPCPQDPLGAAR------CVVHGAEFWSQYRIN 172
Query 191 SMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSS-FY 249
V S + Q IL+PDPP + V +V PR L +W P SW S +
Sbjct 173 VTEVNPLGASTRLLDVSLQS--ILRPDPPQGLRVESVPGYPRRLRASWTYPASWPSQPHF 230
Query 250 RLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPE 309
L+F L+YR + ++T L+ VI DA +GL H V++ A++ G WS WSPE
Sbjct 231 LLKFRLQYRPAQHPAWSTVEPAGLEE--VITDAVAGLPHAVRVSARDFLDAGTWSTWSPE 288
Query 310 AMGTP 314
A GTP
Sbjct 289 AWGTP 293
>8dpu_O O Interleukin-11 receptor subunit alpha
Length=348
Score = 103 bits (256), Expect = 5e-23, Method: Compositional matrix adjust.
Identities = 97/305 (32%), Positives = 129/305 (42%), Gaps = 30/305 (10%)
Query 25 CPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLR-KPAAGSHPSRWAGMGRRLLL 83
CP GV PG SV L CPGV D V W +P P +G+G L+L
Sbjct 4 CPQAWGPPGVQYGQPGRSVKLCCPGVTAGD--PVSWFRDGEPKLLQGPD--SGLGHELVL 59
Query 84 RSVQLHDSGNYSCYRA-GRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSL 142
D G Y C G GTV L + PP P +SC + + N C W P L
Sbjct 60 AQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC-QAADYENFSCTWSPSQISGL 118
Query 143 TTKAVLLVRKF------------QNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIV 190
T+ + RK P Q+P ++ C + E S + I
Sbjct 119 PTRYLTSYRKKTVXXXXXXXXXPSTGPWPCPQDPLGAAR------CVVHGAEFWSQYRIN 172
Query 191 SMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSS-FY 249
V S + Q IL+PDPP + V +V PR L +W P SW S +
Sbjct 173 VTEVNPLGASTRLLDVSLQS--ILRPDPPQGLRVESVPGYPRRLRASWTYPASWPSQPHF 230
Query 250 RLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPE 309
L+F L+YR + ++T L+ VI DA +GL H V++ A++ G WS WSPE
Sbjct 231 LLKFRLQYRPAQHPAWSTVEPAGLEE--VITDAVAGLPHAVRVSARDFLDAGTWSTWSPE 288
Query 310 AMGTP 314
A GTP
Sbjct 289 AWGTP 293
>8dpu_F F Interleukin-11 receptor subunit alpha
Length=348
Score = 103 bits (256), Expect = 5e-23, Method: Compositional matrix adjust.
Identities = 97/305 (32%), Positives = 129/305 (42%), Gaps = 30/305 (10%)
Query 25 CPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLR-KPAAGSHPSRWAGMGRRLLL 83
CP GV PG SV L CPGV D V W +P P +G+G L+L
Sbjct 4 CPQAWGPPGVQYGQPGRSVKLCCPGVTAGD--PVSWFRDGEPKLLQGPD--SGLGHELVL 59
Query 84 RSVQLHDSGNYSCYRA-GRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSL 142
D G Y C G GTV L + PP P +SC + + N C W P L
Sbjct 60 AQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC-QAADYENFSCTWSPSQISGL 118
Query 143 TTKAVLLVRKF------------QNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIV 190
T+ + RK P Q+P ++ C + E S + I
Sbjct 119 PTRYLTSYRKKTVXXXXXXXXXPSTGPWPCPQDPLGAAR------CVVHGAEFWSQYRIN 172
Query 191 SMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSS-FY 249
V S + Q IL+PDPP + V +V PR L +W P SW S +
Sbjct 173 VTEVNPLGASTRLLDVSLQS--ILRPDPPQGLRVESVPGYPRRLRASWTYPASWPSQPHF 230
Query 250 RLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPE 309
L+F L+YR + ++T L+ VI DA +GL H V++ A++ G WS WSPE
Sbjct 231 LLKFRLQYRPAQHPAWSTVEPAGLEE--VITDAVAGLPHAVRVSARDFLDAGTWSTWSPE 288
Query 310 AMGTP 314
A GTP
Sbjct 289 AWGTP 293
>8dpu_L L Interleukin-11 receptor subunit alpha
Length=348
Score = 103 bits (256), Expect = 5e-23, Method: Compositional matrix adjust.
Identities = 97/305 (32%), Positives = 129/305 (42%), Gaps = 30/305 (10%)
Query 25 CPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLR-KPAAGSHPSRWAGMGRRLLL 83
CP GV PG SV L CPGV D V W +P P +G+G L+L
Sbjct 4 CPQAWGPPGVQYGQPGRSVKLCCPGVTAGD--PVSWFRDGEPKLLQGPD--SGLGHELVL 59
Query 84 RSVQLHDSGNYSCYRA-GRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSL 142
D G Y C G GTV L + PP P +SC + + N C W P L
Sbjct 60 AQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC-QAADYENFSCTWSPSQISGL 118
Query 143 TTKAVLLVRKF------------QNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIV 190
T+ + RK P Q+P ++ C + E S + I
Sbjct 119 PTRYLTSYRKKTVXXXXXXXXXPSTGPWPCPQDPLGAAR------CVVHGAEFWSQYRIN 172
Query 191 SMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSS-FY 249
V S + Q IL+PDPP + V +V PR L +W P SW S +
Sbjct 173 VTEVNPLGASTRLLDVSLQS--ILRPDPPQGLRVESVPGYPRRLRASWTYPASWPSQPHF 230
Query 250 RLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPE 309
L+F L+YR + ++T L+ VI DA +GL H V++ A++ G WS WSPE
Sbjct 231 LLKFRLQYRPAQHPAWSTVEPAGLEE--VITDAVAGLPHAVRVSARDFLDAGTWSTWSPE 288
Query 310 AMGTP 314
A GTP
Sbjct 289 AWGTP 293
>8dpu_I I Interleukin-11 receptor subunit alpha
Length=348
Score = 103 bits (256), Expect = 5e-23, Method: Compositional matrix adjust.
Identities = 97/305 (32%), Positives = 129/305 (42%), Gaps = 30/305 (10%)
Query 25 CPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLR-KPAAGSHPSRWAGMGRRLLL 83
CP GV PG SV L CPGV D V W +P P +G+G L+L
Sbjct 4 CPQAWGPPGVQYGQPGRSVKLCCPGVTAGD--PVSWFRDGEPKLLQGPD--SGLGHELVL 59
Query 84 RSVQLHDSGNYSCYRA-GRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSL 142
D G Y C G GTV L + PP P +SC + + N C W P L
Sbjct 60 AQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC-QAADYENFSCTWSPSQISGL 118
Query 143 TTKAVLLVRKF------------QNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIV 190
T+ + RK P Q+P ++ C + E S + I
Sbjct 119 PTRYLTSYRKKTVXXXXXXXXXPSTGPWPCPQDPLGAAR------CVVHGAEFWSQYRIN 172
Query 191 SMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSS-FY 249
V S + Q IL+PDPP + V +V PR L +W P SW S +
Sbjct 173 VTEVNPLGASTRLLDVSLQS--ILRPDPPQGLRVESVPGYPRRLRASWTYPASWPSQPHF 230
Query 250 RLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPE 309
L+F L+YR + ++T L+ VI DA +GL H V++ A++ G WS WSPE
Sbjct 231 LLKFRLQYRPAQHPAWSTVEPAGLEE--VITDAVAGLPHAVRVSARDFLDAGTWSTWSPE 288
Query 310 AMGTP 314
A GTP
Sbjct 289 AWGTP 293
>8dpu_C C Interleukin-11 receptor subunit alpha
Length=348
Score = 103 bits (256), Expect = 5e-23, Method: Compositional matrix adjust.
Identities = 97/305 (32%), Positives = 129/305 (42%), Gaps = 30/305 (10%)
Query 25 CPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLR-KPAAGSHPSRWAGMGRRLLL 83
CP GV PG SV L CPGV D V W +P P +G+G L+L
Sbjct 4 CPQAWGPPGVQYGQPGRSVKLCCPGVTAGD--PVSWFRDGEPKLLQGPD--SGLGHELVL 59
Query 84 RSVQLHDSGNYSCYRA-GRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWGPRSTPSL 142
D G Y C G GTV L + PP P +SC + + N C W P L
Sbjct 60 AQADSTDEGTYICQTLDGALGGTVTLQLGYPPARPVVSC-QAADYENFSCTWSPSQISGL 118
Query 143 TTKAVLLVRKF------------QNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIV 190
T+ + RK P Q+P ++ C + E S + I
Sbjct 119 PTRYLTSYRKKTVXXXXXXXXXPSTGPWPCPQDPLGAAR------CVVHGAEFWSQYRIN 172
Query 191 SMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSS-FY 249
V S + Q IL+PDPP + V +V PR L +W P SW S +
Sbjct 173 VTEVNPLGASTRLLDVSLQS--ILRPDPPQGLRVESVPGYPRRLRASWTYPASWPSQPHF 230
Query 250 RLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPE 309
L+F L+YR + ++T L+ VI DA +GL H V++ A++ G WS WSPE
Sbjct 231 LLKFRLQYRPAQHPAWSTVEPAGLEE--VITDAVAGLPHAVRVSARDFLDAGTWSTWSPE 288
Query 310 AMGTP 314
A GTP
Sbjct 289 AWGTP 293
>8d7h_A C Ciliary neurotrophic factor receptor subunit alpha
Length=348
Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 77/247 (31%), Positives = 116/247 (47%), Gaps = 20/247 (8%)
Query 78 GRRLLLRSVQLHDSGNYSCYR--AGRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWG 135
G +L+L ++L SG Y+C+ + V L V +PP EP LSC + C W
Sbjct 49 GSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPKGFYCSWH 108
Query 136 ---PRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSF-YIVS 191
P P+ VL K C+ + K C + S+ Y VS
Sbjct 109 LPTPTYIPNTFNVTVLHGSKIM---------VCE-KDPALKNRCHIRYMHLFSTIKYKVS 158
Query 192 MCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSW-NSSFYR 250
+ V++++G + TF I++PDPP N+ V NPR L VTWQ P +W + +
Sbjct 159 ISVSNALGHNATAI-TFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFP 217
Query 251 LRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEA 310
L+F LRYR + + D H + DA++G +++Q+ A++ G WS+WS A
Sbjct 218 LKFFLRYRPLILDQWQHVELSDGTAHTIT-DAYAGKEYIIQVAAKDN-EIGTWSDWSVAA 275
Query 311 MGTPWTE 317
TPWTE
Sbjct 276 HATPWTE 282
>8d7e_A C Ciliary neurotrophic factor receptor subunit alpha
Length=348
Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 77/247 (31%), Positives = 116/247 (47%), Gaps = 20/247 (8%)
Query 78 GRRLLLRSVQLHDSGNYSCYR--AGRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWG 135
G +L+L ++L SG Y+C+ + V L V +PP EP LSC + C W
Sbjct 49 GSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPKGFYCSWH 108
Query 136 ---PRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSF-YIVS 191
P P+ VL K C+ + K C + S+ Y VS
Sbjct 109 LPTPTYIPNTFNVTVLHGSKIM---------VCE-KDPALKNRCHIRYMHLFSTIKYKVS 158
Query 192 MCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSW-NSSFYR 250
+ V++++G + TF I++PDPP N+ V NPR L VTWQ P +W + +
Sbjct 159 ISVSNALGHNATAI-TFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFP 217
Query 251 LRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEA 310
L+F LRYR + + D H + DA++G +++Q+ A++ G WS+WS A
Sbjct 218 LKFFLRYRPLILDQWQHVELSDGTAHTIT-DAYAGKEYIIQVAAKDN-EIGTWSDWSVAA 275
Query 311 MGTPWTE 317
TPWTE
Sbjct 276 HATPWTE 282
>8d7h_D G Ciliary neurotrophic factor receptor subunit alpha
Length=348
Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 77/247 (31%), Positives = 116/247 (47%), Gaps = 20/247 (8%)
Query 78 GRRLLLRSVQLHDSGNYSCYR--AGRPAGTVHLLVDVPPEEPQLSCFRKSPLSNVVCEWG 135
G +L+L ++L SG Y+C+ + V L V +PP EP LSC + C W
Sbjct 49 GSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPKGFYCSWH 108
Query 136 ---PRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSF-YIVS 191
P P+ VL K C+ + K C + S+ Y VS
Sbjct 109 LPTPTYIPNTFNVTVLHGSKIM---------VCE-KDPALKNRCHIRYMHLFSTIKYKVS 158
Query 192 MCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSW-NSSFYR 250
+ V++++G + TF I++PDPP N+ V NPR L VTWQ P +W + +
Sbjct 159 ISVSNALGHNATAI-TFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFP 217
Query 251 LRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEA 310
L+F LRYR + + D H + DA++G +++Q+ A++ G WS+WS A
Sbjct 218 LKFFLRYRPLILDQWQHVELSDGTAHTIT-DAYAGKEYIIQVAAKDN-EIGTWSDWSVAA 275
Query 311 MGTPWTE 317
TPWTE
Sbjct 276 HATPWTE 282
>8d74_C C Ciliary neurotrophic factor receptor subunit alpha
Length=320
Score = 86.3 bits (212), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 67/211 (32%), Positives = 98/211 (46%), Gaps = 18/211 (9%)
Query 112 VPPEEPQLSCFRKSPLSNVVCEWG---PRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYS 168
+PP EP LSC + C W P P+ VL K C+
Sbjct 85 LPPREPVLSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMV---------CE-K 134
Query 169 QESQKFSCQLAVPEGDSSF-YIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAV 227
+ K C + S+ Y VS+ V++++G + TF I++PDPP N+ V
Sbjct 135 DPALKNRCHIRYMHLFSTIKYKVSISVSNALGHN-ATAITFDEFTIVKPDPPENVVARPV 193
Query 228 ARNPRWLSVTWQDPHSW-NSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL 286
NPR L VTWQ P +W + + L+F LRYR + + D H I DA++G
Sbjct 194 PSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSDGTAH-TITDAYAGK 252
Query 287 RHVVQLRAQEEFGQGEWSEWSPEAMGTPWTE 317
+++Q+ A++ G WS+WS A TPWTE
Sbjct 253 EYIIQVAAKDN-EIGTWSDWSVAAHATPWTE 282
>8d7r_B C Ciliary neurotrophic factor receptor subunit alpha
Length=324
Score = 86.3 bits (212), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 67/211 (32%), Positives = 98/211 (46%), Gaps = 18/211 (9%)
Query 112 VPPEEPQLSCFRKSPLSNVVCEWG---PRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYS 168
+PP EP LSC + C W P P+ VL K C+
Sbjct 85 LPPREPVLSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMV---------CE-K 134
Query 169 QESQKFSCQLAVPEGDSSF-YIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAV 227
+ K C + S+ Y VS+ V++++G + TF I++PDPP N+ V
Sbjct 135 DPALKNRCHIRYMHLFSTIKYKVSISVSNALGHN-ATAITFDEFTIVKPDPPENVVARPV 193
Query 228 ARNPRWLSVTWQDPHSW-NSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL 286
NPR L VTWQ P +W + + L+F LRYR + + D H I DA++G
Sbjct 194 PSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSDGTAH-TITDAYAGK 252
Query 287 RHVVQLRAQEEFGQGEWSEWSPEAMGTPWTE 317
+++Q+ A++ G WS+WS A TPWTE
Sbjct 253 EYIIQVAAKDN-EIGTWSDWSVAAHATPWTE 282
>1uc6_A A Ciliary Neurotrophic Factor Receptor alpha
Length=109
Score = 69.7 bits (169), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 42/110 (38%), Positives = 60/110 (55%), Gaps = 7/110 (6%)
Query 211 CGILQPDPPANITVTAVARNPRWLSVTWQDPHSW-NSSFYRLRFELRYRAERSKTFTTWM 269
G ++PDPP N+ V NPR L VTWQ P +W + + L+F LRYR W
Sbjct 3 LGSVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRP---LILDQWQ 59
Query 270 VKDLQHHC--VIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTE 317
+L + I DA++G +++Q+ A++ G WS+WS A TPWTE
Sbjct 60 HVELSNGTAHTITDAYAGKEYIIQVAAKDN-EIGTWSDWSVAAHATPWTE 108
>8dps_C C Interleukin-11 receptor subunit alpha
Length=298
Score = 73.6 bits (179), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 63/212 (30%), Positives = 92/212 (43%), Gaps = 18/212 (8%)
Query 113 PPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQE-------PC 165
PP P +SC + + N C W P L T+ + RK PC
Sbjct 91 PPARPVVSC-QAADYENFSCTWSPSQISGLPTRYLTSYRKKTVXXXXXXXXXPSTGPWPC 149
Query 166 QYSQESQKFSCQLAVPEGDS--SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANIT 223
V G S Y +++ + +G+ ++ IL+PDPP +
Sbjct 150 ----PQDPLGAARCVVHGAEFWSQYRINVTEVNPLGAS-TRLLDVSLQSILRPDPPQGLR 204
Query 224 VTAVARNPRWLSVTWQDPHSWNSS-FYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDA 282
V +V PR L +W P SW S + L+F L+YR + ++T L+ VI DA
Sbjct 205 VESVPGYPRRLRASWTYPASWPSQPHFLLKFRLQYRPAQHPAWSTVEPAGLEE--VITDA 262
Query 283 WSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTP 314
+GL H V++ A++ G WS WSPEA GTP
Sbjct 263 VAGLPHAVRVSARDFLDAGTWSTWSPEAWGTP 294
>8dps_F F Interleukin-11 receptor subunit alpha
Length=298
Score = 73.6 bits (179), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 63/212 (30%), Positives = 92/212 (43%), Gaps = 18/212 (8%)
Query 113 PPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQE-------PC 165
PP P +SC + + N C W P L T+ + RK PC
Sbjct 91 PPARPVVSC-QAADYENFSCTWSPSQISGLPTRYLTSYRKKTVXXXXXXXXXPSTGPWPC 149
Query 166 QYSQESQKFSCQLAVPEGDS--SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANIT 223
V G S Y +++ + +G+ ++ IL+PDPP +
Sbjct 150 ----PQDPLGAARCVVHGAEFWSQYRINVTEVNPLGAS-TRLLDVSLQSILRPDPPQGLR 204
Query 224 VTAVARNPRWLSVTWQDPHSWNSS-FYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDA 282
V +V PR L +W P SW S + L+F L+YR + ++T L+ VI DA
Sbjct 205 VESVPGYPRRLRASWTYPASWPSQPHFLLKFRLQYRPAQHPAWSTVEPAGLEE--VITDA 262
Query 283 WSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTP 314
+GL H V++ A++ G WS WSPEA GTP
Sbjct 263 VAGLPHAVRVSARDFLDAGTWSTWSPEAWGTP 294
>8qy4_F E Interleukin-11 receptor subunit alpha
Length=422
Score = 72.4 bits (176), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 60/208 (29%), Positives = 90/208 (43%), Gaps = 10/208 (5%)
Query 113 PPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRK---FQNSPAEDFQEPCQYSQ 169
PP P +SC + + N C W P L T+ + RK +
Sbjct 112 PPARPVVSC-QAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLXXXXXXXXXSTGPWPC 170
Query 170 ESQKFSCQLAVPEGDS--SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAV 227
V G S Y +++ + +G+ ++ IL+PDPP + V +V
Sbjct 171 PQDPLGAARCVVHGAEFWSQYRINVTEVNPLGAS-TRLLDVSLQSILRPDPPQGLRVESV 229
Query 228 ARNPRWLSVTWQDPHSWNSS-FYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL 286
PR L +W P SW + L+F L+YR + ++T L+ VI DA +GL
Sbjct 230 PGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEE--VITDAVAGL 287
Query 287 RHVVQLRAQEEFGQGEWSEWSPEAMGTP 314
H V++ A++ G WS WSPEA GTP
Sbjct 288 PHAVRVSARDFLDAGTWSTWSPEAWGTP 315
>8qy4_E B Interleukin-11 receptor subunit alpha
Length=422
Score = 72.4 bits (176), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 60/208 (29%), Positives = 90/208 (43%), Gaps = 10/208 (5%)
Query 113 PPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRK---FQNSPAEDFQEPCQYSQ 169
PP P +SC + + N C W P L T+ + RK +
Sbjct 112 PPARPVVSC-QAADYENFSCTWSPSQISGLPTRYLTSYRKKTVLXXXXXXXXXSTGPWPC 170
Query 170 ESQKFSCQLAVPEGDS--SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAV 227
V G S Y +++ + +G+ ++ IL+PDPP + V +V
Sbjct 171 PQDPLGAARCVVHGAEFWSQYRINVTEVNPLGAS-TRLLDVSLQSILRPDPPQGLRVESV 229
Query 228 ARNPRWLSVTWQDPHSWNSS-FYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL 286
PR L +W P SW + L+F L+YR + ++T L+ VI DA +GL
Sbjct 230 PGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAWSTVEPAGLEE--VITDAVAGL 287
Query 287 RHVVQLRAQEEFGQGEWSEWSPEAMGTP 314
H V++ A++ G WS WSPEA GTP
Sbjct 288 PHAVRVSARDFLDAGTWSTWSPEAWGTP 315
>1f42_A A INTERLEUKIN-12 BETA CHAIN
Length=306
Score = 60.8 bits (146), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 69/303 (23%), Positives = 120/303 (40%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 20 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 70
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 71 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 130
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 131 TFSVKSSRGXXXXXGVTCGAATLSAERVRGDNKEY----EYSVECQEDS---ACPAAEES 183
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + +N R + V+W+ P +W++
Sbjct 184 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTWST 242
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + + + D VI + +RAQ+ + WS
Sbjct 243 PHSYFSLTFCVQVQGKSKRXXXXRVFTDKTSATVICRK----NASISVRAQDRYYSSSWS 298
Query 305 EWS 307
EW+
Sbjct 299 EWA 301
>8d7h_F E Cytokine receptor-like factor 1
Length=395
Score = 60.8 bits (146), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 63/236 (27%), Positives = 99/236 (42%), Gaps = 23/236 (10%)
Query 93 NYSCY-RAGRPAGTVHLLVDVPPEEP-QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLV 150
N C+ R G L V +PPE+P +SC+ K+ + ++ C W P + +
Sbjct 76 NLVCHARDGSILAGSCLYVGLPPEKPVNISCWSKN-MKDLTCRWTPGAHGETFLHTNYSL 134
Query 151 RKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSF--YIVSMCVASSVGSKFSKTQTF 208
+ +D C+ SC +P+ + F Y + + + +GS S T
Sbjct 135 KYKLRWYGQD--NTCEEYHTVGPHSCH--IPKDLALFTPYEIWVEATNRLGSARSDVLTL 190
Query 209 QGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTW 268
++ DPP ++ V+ V LSV W P + ++ ++++RYR E S W
Sbjct 191 DILDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDS---VDW 247
Query 269 MVKD---LQHHCVIHDAWSGLRHVVQLRAQEEFG------QGEWSEWS-PEAMGTP 314
V D Q C + G + VQ+R FG G WSEWS P A TP
Sbjct 248 KVVDDVSNQTSCRLAGLKPGTVYFVQVRCN-PFGIYGSKKAGIWSEWSHPTAASTP 302
>8d7h_C A Cytokine receptor-like factor 1
Length=395
Score = 60.8 bits (146), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 63/236 (27%), Positives = 99/236 (42%), Gaps = 23/236 (10%)
Query 93 NYSCY-RAGRPAGTVHLLVDVPPEEP-QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLV 150
N C+ R G L V +PPE+P +SC+ K+ + ++ C W P + +
Sbjct 76 NLVCHARDGSILAGSCLYVGLPPEKPVNISCWSKN-MKDLTCRWTPGAHGETFLHTNYSL 134
Query 151 RKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSF--YIVSMCVASSVGSKFSKTQTF 208
+ +D C+ SC +P+ + F Y + + + +GS S T
Sbjct 135 KYKLRWYGQD--NTCEEYHTVGPHSCH--IPKDLALFTPYEIWVEATNRLGSARSDVLTL 190
Query 209 QGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTW 268
++ DPP ++ V+ V LSV W P + ++ ++++RYR E S W
Sbjct 191 DILDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDS---VDW 247
Query 269 MVKD---LQHHCVIHDAWSGLRHVVQLRAQEEFG------QGEWSEWS-PEAMGTP 314
V D Q C + G + VQ+R FG G WSEWS P A TP
Sbjct 248 KVVDDVSNQTSCRLAGLKPGTVYFVQVRCN-PFGIYGSKKAGIWSEWSHPTAASTP 302
>3duh_A A Interleukin-12 subunit beta
Length=314
Score = 60.1 bits (144), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 69/303 (23%), Positives = 119/303 (39%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 22 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 72
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 73 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 132
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + ++ +YS E Q+ S A P + S
Sbjct 133 TFSVKSSRGSSDPQGVTCGAATLSAEXXXXXXXEY----EYSVECQEDS---ACPAAEES 185
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + +N R + V+W+ P +W++
Sbjct 186 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTWST 244
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + + + D VI + +RAQ+ + WS
Sbjct 245 PHSYFSLTFCVQVQGKSKREKKDRVFTDKTSATVI----CRKNASISVRAQDRYYSSSWS 300
Query 305 EWS 307
EW+
Sbjct 301 EWA 303
>5mzv_A A Interleukin-12 subunit beta
Length=328
Score = 59.7 bits (143), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 69/303 (23%), Positives = 120/303 (40%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 42 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 92
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 93 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 152
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 153 TFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEY----EYSVECQEDS---ACPAAEES 205
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + +N R + V+W+ P +W++
Sbjct 206 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTWST 264
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + + + D VI + +RAQ+ + WS
Sbjct 265 PHSYFSLTFCVQVQGKXXREKKDRVFTDKTSATVI----CRKNASISVRAQDRYYSSSWS 320
Query 305 EWS 307
EW+
Sbjct 321 EWA 323
>6wdq_A A Interleukin-12 subunit beta
Length=308
Score = 59.3 bits (142), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 69/303 (23%), Positives = 119/303 (39%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 22 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 72
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 73 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 132
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 133 TFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEY----EYSVECQEDS---ACPAAEES 185
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + +N R + V+W+ P +W++
Sbjct 186 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTWST 244
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + + D VI + +RAQ+ + WS
Sbjct 245 PHSYFSLTFCVQVQGKSKXXXXDRVFTDKTSATVI----CRKNASISVRAQDRYYSSSWS 300
Query 305 EWS 307
EW+
Sbjct 301 EWA 303
>8oe4_A A Interleukin-12 subunit beta
Length=306
Score = 59.3 bits (142), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 71/305 (23%), Positives = 121/305 (40%), Gaps = 59/305 (19%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 20 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 70
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 71 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 130
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 131 TFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEY----EYSVECQEDS---ACPAAEES 183
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + +N R + V+W+ P +W++
Sbjct 184 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTWST 242
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVI--HDAWSGLRHVVQLRAQEEFGQGE 302
S++ L F ++ + + + D VI DA + +RAQ+ +
Sbjct 243 PHSYFSLTFCVQVQGKXXXXKKDRVFTDKTSATVICRKDA------SISVRAQDRYYSSS 296
Query 303 WSEWS 307
WSEW+
Sbjct 297 WSEWA 301
>3hmx_A A Interleukin-12 subunit beta
Length=306
Score = 58.2 bits (139), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 69/303 (23%), Positives = 118/303 (39%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 20 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 70
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 71 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 130
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 131 TFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEY----EYSVECQEDS---ACPAAEES 183
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + +N R + V+W+ P +W++
Sbjct 184 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTWST 242
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + D VI + +RAQ+ + WS
Sbjct 243 PHSYFSLTFCVQVQXXXXXXXKDRVFTDKTSATVI----CRXXXSISVRAQDRYYSSSWS 298
Query 305 EWS 307
EW+
Sbjct 299 EWA 301
>3qwr_A A Interleukin-12 subunit beta
Length=306
Score = 57.8 bits (138), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 69/303 (23%), Positives = 118/303 (39%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 20 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 70
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 71 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 130
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 131 TFSVKSSRGSSDPQGVTCGAATLSAERXRGDNKEY----EYSVECQEDS---ACPAAEES 183
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + +N R + V+W+ P +W++
Sbjct 184 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTWST 242
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + D VI + +RAQ+ + WS
Sbjct 243 PHSYFSLTFCVQVQXXXXXXKKDRVFTDKTSATVI----CRKXXSISVRAQDRYYSSSWS 298
Query 305 EWS 307
EW+
Sbjct 299 EWA 301
>4grw_B B Interleukin-12 subunit beta
Length=328
Score = 58.2 bits (139), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 69/303 (23%), Positives = 118/303 (39%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 42 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 92
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 93 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 152
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 153 TFSVKSSRGXXXPQGVTCGAATLSAERVRXXNKEY----EYSVECQEDS---ACPAAEES 205
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + +N R + V+W+ P +W++
Sbjct 206 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTWST 264
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + D VI + +RAQ+ + WS
Sbjct 265 PHSYFSLTFCVQVQGXXXXXXXDRVFTDKTSATVI----CRKNASISVRAQDRYYSSSWS 320
Query 305 EWS 307
EW+
Sbjct 321 EWA 323
>5mj3_A A Interleukin-12 subunit beta
Length=306
Score = 57.8 bits (138), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 69/303 (23%), Positives = 118/303 (39%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 20 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 70
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 71 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 130
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 131 TFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEY----EYSVECQEDS---ACPAAEES 183
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + +N R + V+W+ P +W++
Sbjct 184 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTWST 242
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + D VI + +RAQ+ + WS
Sbjct 243 PHSYFSLTFCVQVQGXXXXEKKDRVFTDKTSATVI----CRKNASISVRAQDRYYSSSWS 298
Query 305 EWS 307
EW+
Sbjct 299 EWA 301
>3d87_B B Interleukin-12 subunit p40
Length=306
Score = 57.4 bits (137), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 69/303 (23%), Positives = 117/303 (39%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 20 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 70
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 71 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 130
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 131 TFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEY----EYSVECQEDS---ACPAAEES 183
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A T +F I++PDPP N+ + + +N R + V+W+ P +W++
Sbjct 184 LPIEVMVDAVHKLKYEQYTSSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTWST 242
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + D VI + +RAQ+ + WS
Sbjct 243 PHSYFSLTFCVQVQXXXXXXXXDRVFTDKTSATVI----CRKNASISVRAQDRYYSSSWS 298
Query 305 EWS 307
EW+
Sbjct 299 EWA 301
>3d87_D D Interleukin-12 subunit p40
Length=306
Score = 57.0 bits (136), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 69/303 (23%), Positives = 116/303 (38%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 20 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 70
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 71 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 130
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 131 TFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEY----EYSVECQEDS---ACPAAEES 183
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A T +F I++PDPP N+ + + +N R + V+W+ P +W++
Sbjct 184 LPIEVMVDAVHKLKYEQYTSSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTWST 242
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + D VI + +RAQ+ + WS
Sbjct 243 PHSYFSLTFCVQVXXXXXXXXXDRVFTDKTSATVI----CRKNASISVRAQDRYYSSSWS 298
Query 305 EWS 307
EW+
Sbjct 299 EWA 301
>5mxa_B A Interleukin-12 subunit beta
Length=328
Score = 55.8 bits (133), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 68/303 (22%), Positives = 118/303 (39%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 42 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 92
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 93 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 152
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 153 TFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEY----EYSVECQEDS---ACPAAEES 205
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + + R + V+W+ P +W++
Sbjct 206 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPL-KXSRQVEVSWEYPDTWST 264
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + + D VI + +RAQ+ + WS
Sbjct 265 PHSYFSLTFCVQVQGKXXXXKKDRVFTDKTSATVI----CRKNASISVRAQDRYYSSSWS 320
Query 305 EWS 307
EW+
Sbjct 321 EWA 323
>1bqu_B B PROTEIN (GP130)
Length=215
Score = 53.9 bits (128), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 55/213 (26%), Positives = 94/213 (44%), Gaps = 29/213 (14%)
Query 112 VPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAEDFQEPCQ 166
+PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 6 LPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-------- 56
Query 167 YSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQPDPPANI 222
+ SC + S+ Y V++ V +++G S F ++P+PP N+
Sbjct 57 --KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNL 110
Query 223 TVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL---QHHCVI 279
+V L +TW +P S L++ ++YR + + T++ +D + +
Sbjct 111 SVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV 168
Query 280 HDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMG 312
D +V ++R +E G+G WS+WS EA G
Sbjct 169 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 201
>1pvh_C C Interleukin-6 receptor beta chain
Length=201
Score = 53.9 bits (128), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 55/213 (26%), Positives = 94/213 (44%), Gaps = 29/213 (14%)
Query 112 VPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAEDFQEPCQ 166
+PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 2 LPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-------- 52
Query 167 YSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQPDPPANI 222
+ SC + S+ Y V++ V +++G S F ++P+PP N+
Sbjct 53 --KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNL 106
Query 223 TVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL---QHHCVI 279
+V L +TW +P S L++ ++YR + + T++ +D + +
Sbjct 107 SVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV 164
Query 280 HDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMG 312
D +V ++R +E G+G WS+WS EA G
Sbjct 165 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 197
>1pvh_A A Interleukin-6 receptor beta chain
Length=201
Score = 53.9 bits (128), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 55/213 (26%), Positives = 94/213 (44%), Gaps = 29/213 (14%)
Query 112 VPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAEDFQEPCQ 166
+PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 2 LPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-------- 52
Query 167 YSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQPDPPANI 222
+ SC + S+ Y V++ V +++G S F ++P+PP N+
Sbjct 53 --KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNL 106
Query 223 TVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL---QHHCVI 279
+V L +TW +P S L++ ++YR + + T++ +D + +
Sbjct 107 SVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV 164
Query 280 HDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMG 312
D +V ++R +E G+G WS+WS EA G
Sbjct 165 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 197
>3l5h_A A Interleukin-6 receptor subunit beta
Length=589
Score = 55.8 bits (133), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 57/230 (25%), Positives = 103/230 (45%), Gaps = 31/230 (13%)
Query 106 VHLLVDVPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAED 160
+ ++ +PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 95 ITIISXLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-- 151
Query 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQP 216
+ SC + S+ Y V++ V +++G S F ++P
Sbjct 152 --------KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 199
Query 217 DPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL--- 273
+PP N++V L +TW +P S L++ ++YR + + T++ +D
Sbjct 200 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTAST 257
Query 274 QHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTE--SRSP 321
+ + D +V ++R +E G+G WS+WS EA G + + S++P
Sbjct 258 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 307
>1bqu_A A PROTEIN (GP130)
Length=215
Score = 53.9 bits (128), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 55/213 (26%), Positives = 94/213 (44%), Gaps = 29/213 (14%)
Query 112 VPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAEDFQEPCQ 166
+PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 6 LPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-------- 56
Query 167 YSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQPDPPANI 222
+ SC + S+ Y V++ V +++G S F ++P+PP N+
Sbjct 57 --KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNL 110
Query 223 TVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL---QHHCVI 279
+V L +TW +P S L++ ++YR + + T++ +D + +
Sbjct 111 SVINSXXLSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV 168
Query 280 HDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMG 312
D +V ++R +E G+G WS+WS EA G
Sbjct 169 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 201
>8d82_F E Interleukin-6 receptor subunit beta
Length=678
Score = 55.8 bits (133), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 57/230 (25%), Positives = 103/230 (45%), Gaps = 31/230 (13%)
Query 106 VHLLVDVPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAED 160
+ ++ +PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 96 ITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-- 152
Query 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQP 216
+ SC + S+ Y V++ V +++G S F ++P
Sbjct 153 --------KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 200
Query 217 DPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL--- 273
+PP N++V L +TW +P S L++ ++YR + + T++ +D
Sbjct 201 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTAST 258
Query 274 QHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTE--SRSP 321
+ + D +V ++R +E G+G WS+WS EA G + + S++P
Sbjct 259 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 308
>8d82_C A Interleukin-6 receptor subunit beta
Length=678
Score = 55.8 bits (133), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 57/230 (25%), Positives = 103/230 (45%), Gaps = 31/230 (13%)
Query 106 VHLLVDVPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAED 160
+ ++ +PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 96 ITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-- 152
Query 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQP 216
+ SC + S+ Y V++ V +++G S F ++P
Sbjct 153 --------KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 200
Query 217 DPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL--- 273
+PP N++V L +TW +P S L++ ++YR + + T++ +D
Sbjct 201 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTAST 258
Query 274 QHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTE--SRSP 321
+ + D +V ++R +E G+G WS+WS EA G + + S++P
Sbjct 259 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 308
>1i1r_A A INTERLEUKIN-6 RECEPTOR BETA CHAIN
Length=303
Score = 54.7 bits (130), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 55/224 (25%), Positives = 99/224 (44%), Gaps = 29/224 (13%)
Query 106 VHLLVDVPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAED 160
+ ++ +PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 96 ITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-- 152
Query 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQP 216
+ SC + S+ Y V++ V +++G S F ++P
Sbjct 153 --------KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 200
Query 217 DPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL--- 273
+PP N++V L +TW +P S L++ ++YR + + T++ +D
Sbjct 201 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTAST 258
Query 274 QHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTE 317
+ + D +V ++R +E G+G WS+WS EA G + +
Sbjct 259 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 302
>3duh_B B Interleukin-12 subunit beta
Length=314
Score = 54.7 bits (130), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 67/303 (22%), Positives = 117/303 (39%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 22 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 72
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 73 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 132
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 133 TFSVKSSRGSSDPQGVTCGAATLSAEXXXXXNKEY----EYSVECQEDS---ACPAAEES 185
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + + + V+W+ P +W++
Sbjct 186 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLXXXXQ-VEVSWEYPDTWST 244
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + + D VI + +RAQ+ + WS
Sbjct 245 PHSYFSLTFCVQVQGKXXXXKKDRVFTDKTSATVI----CRKNASISVRAQDRYYSSSWS 300
Query 305 EWS 307
EW+
Sbjct 301 EWA 303
>8dpu_P P Interleukin-6 receptor subunit beta
Length=303
Score = 54.3 bits (129), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 55/222 (25%), Positives = 98/222 (44%), Gaps = 29/222 (13%)
Query 106 VHLLVDVPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAED 160
+ ++ +PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 97 ITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-- 153
Query 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQP 216
+ SC + S+ Y V++ V +++G S F ++P
Sbjct 154 --------KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 201
Query 217 DPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL--- 273
+PP N++V L +TW +P S L++ ++YR + + T++ +D
Sbjct 202 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTAST 259
Query 274 QHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPW 315
+ + D +V ++R +E G+G WS+WS EA G +
Sbjct 260 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 301
>8dpu_M M Interleukin-6 receptor subunit beta
Length=303
Score = 54.3 bits (129), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 55/222 (25%), Positives = 98/222 (44%), Gaps = 29/222 (13%)
Query 106 VHLLVDVPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAED 160
+ ++ +PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 97 ITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-- 153
Query 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQP 216
+ SC + S+ Y V++ V +++G S F ++P
Sbjct 154 --------KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 201
Query 217 DPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL--- 273
+PP N++V L +TW +P S L++ ++YR + + T++ +D
Sbjct 202 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTAST 259
Query 274 QHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPW 315
+ + D +V ++R +E G+G WS+WS EA G +
Sbjct 260 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 301
>8dpu_G G Interleukin-6 receptor subunit beta
Length=303
Score = 54.3 bits (129), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 55/222 (25%), Positives = 98/222 (44%), Gaps = 29/222 (13%)
Query 106 VHLLVDVPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAED 160
+ ++ +PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 97 ITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-- 153
Query 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQP 216
+ SC + S+ Y V++ V +++G S F ++P
Sbjct 154 --------KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 201
Query 217 DPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL--- 273
+PP N++V L +TW +P S L++ ++YR + + T++ +D
Sbjct 202 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTAST 259
Query 274 QHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPW 315
+ + D +V ++R +E G+G WS+WS EA G +
Sbjct 260 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 301
>8dpu_D D Interleukin-6 receptor subunit beta
Length=303
Score = 54.3 bits (129), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 55/222 (25%), Positives = 98/222 (44%), Gaps = 29/222 (13%)
Query 106 VHLLVDVPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAED 160
+ ++ +PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 97 ITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-- 153
Query 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQP 216
+ SC + S+ Y V++ V +++G S F ++P
Sbjct 154 --------KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 201
Query 217 DPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL--- 273
+PP N++V L +TW +P S L++ ++YR + + T++ +D
Sbjct 202 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTAST 259
Query 274 QHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPW 315
+ + D +V ++R +E G+G WS+WS EA G +
Sbjct 260 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 301
>8dpu_J J Interleukin-6 receptor subunit beta
Length=303
Score = 54.3 bits (129), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 55/222 (25%), Positives = 98/222 (44%), Gaps = 29/222 (13%)
Query 106 VHLLVDVPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAED 160
+ ++ +PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 97 ITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-- 153
Query 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQP 216
+ SC + S+ Y V++ V +++G S F ++P
Sbjct 154 --------KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 201
Query 217 DPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL--- 273
+PP N++V L +TW +P S L++ ++YR + + T++ +D
Sbjct 202 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTAST 259
Query 274 QHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPW 315
+ + D +V ++R +E G+G WS+WS EA G +
Sbjct 260 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 301
>8dpu_A A Interleukin-6 receptor subunit beta
Length=303
Score = 54.3 bits (129), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 55/222 (25%), Positives = 98/222 (44%), Gaps = 29/222 (13%)
Query 106 VHLLVDVPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAED 160
+ ++ +PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 97 ITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-- 153
Query 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQP 216
+ SC + S+ Y V++ V +++G S F ++P
Sbjct 154 --------KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 201
Query 217 DPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL--- 273
+PP N++V L +TW +P S L++ ++YR + + T++ +D
Sbjct 202 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTAST 259
Query 274 QHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPW 315
+ + D +V ++R +E G+G WS+WS EA G +
Sbjct 260 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 301
>8dps_D D Interleukin-6 receptor subunit beta
Length=303
Score = 54.3 bits (129), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 55/222 (25%), Positives = 98/222 (44%), Gaps = 29/222 (13%)
Query 106 VHLLVDVPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAED 160
+ ++ +PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 97 ITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-- 153
Query 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQP 216
+ SC + S+ Y V++ V +++G S F ++P
Sbjct 154 --------KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 201
Query 217 DPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL--- 273
+PP N++V L +TW +P S L++ ++YR + + T++ +D
Sbjct 202 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTAST 259
Query 274 QHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPW 315
+ + D +V ++R +E G+G WS+WS EA G +
Sbjct 260 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 301
>8dps_A A Interleukin-6 receptor subunit beta
Length=303
Score = 54.3 bits (129), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 55/222 (25%), Positives = 98/222 (44%), Gaps = 29/222 (13%)
Query 106 VHLLVDVPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAED 160
+ ++ +PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 97 ITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-- 153
Query 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQP 216
+ SC + S+ Y V++ V +++G S F ++P
Sbjct 154 --------KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 201
Query 217 DPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL--- 273
+PP N++V L +TW +P S L++ ++YR + + T++ +D
Sbjct 202 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTAST 259
Query 274 QHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPW 315
+ + D +V ++R +E G+G WS+WS EA G +
Sbjct 260 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITY 301
>7u7n_B B Interleukin-6 receptor subunit beta
Length=299
Score = 54.3 bits (129), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 55/219 (25%), Positives = 97/219 (44%), Gaps = 29/219 (13%)
Query 106 VHLLVDVPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAED 160
+ ++ +PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 96 ITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-- 152
Query 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQP 216
+ SC + S+ Y V++ V +++G S F ++P
Sbjct 153 --------KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 200
Query 217 DPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL--- 273
+PP N++V L +TW +P S L++ ++YR + + T++ +D
Sbjct 201 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTAST 258
Query 274 QHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMG 312
+ + D +V ++R +E G+G WS+WS EA G
Sbjct 259 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 297
>1p9m_A A Interleukin-6 receptor beta chain
Length=299
Score = 54.3 bits (129), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 55/219 (25%), Positives = 97/219 (44%), Gaps = 29/219 (13%)
Query 106 VHLLVDVPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAED 160
+ ++ +PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 96 ITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-- 152
Query 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQP 216
+ SC + S+ Y V++ V +++G S F ++P
Sbjct 153 --------KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 200
Query 217 DPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL--- 273
+PP N++V L +TW +P S L++ ++YR + + T++ +D
Sbjct 201 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTAST 258
Query 274 QHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMG 312
+ + D +V ++R +E G+G WS+WS EA G
Sbjct 259 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 297
>8cr8_A A Interleukin-12 subunit beta
Length=325
Score = 54.7 bits (130), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 71/305 (23%), Positives = 118/305 (39%), Gaps = 59/305 (19%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC ED T W L S G G+ L ++ + D+G Y+C++
Sbjct 39 PGEMVVLTCD-XXXEDGIT--WTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 89
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 90 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 149
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 150 TFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEY----EYSVECQEDS---ACPAAEES 202
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + + R + V+W+ P +W++
Sbjct 203 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPL-KXSRQVEVSWEYPDTWST 261
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVI--HDAWSGLRHVVQLRAQEEFGQGE 302
S++ L F ++ + + + D VI DA + +RAQ+ +
Sbjct 262 PHSYFSLTFCVQVQGKXXXXKKDRVFTDKTSATVICRKDA------SISVRAQDRYYSSS 315
Query 303 WSEWS 307
WSEW+
Sbjct 316 WSEWA 320
>8dpt_D D Interleukin-6 receptor subunit beta
Length=591
Score = 55.1 bits (131), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 57/230 (25%), Positives = 103/230 (45%), Gaps = 31/230 (13%)
Query 106 VHLLVDVPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAED 160
+ ++ +PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 97 ITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-- 153
Query 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQP 216
+ SC + S+ Y V++ V +++G S F ++P
Sbjct 154 --------KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 201
Query 217 DPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL--- 273
+PP N++V L +TW +P S L++ ++YR + + T++ +D
Sbjct 202 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTAST 259
Query 274 QHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTE--SRSP 321
+ + D +V ++R +E G+G WS+WS EA G + + S++P
Sbjct 260 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 309
>8dpt_A A Interleukin-6 receptor subunit beta
Length=591
Score = 55.1 bits (131), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 57/230 (25%), Positives = 103/230 (45%), Gaps = 31/230 (13%)
Query 106 VHLLVDVPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAED 160
+ ++ +PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 97 ITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-- 153
Query 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQP 216
+ SC + S+ Y V++ V +++G S F ++P
Sbjct 154 --------KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 201
Query 217 DPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL--- 273
+PP N++V L +TW +P S L++ ++YR + + T++ +D
Sbjct 202 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTAST 259
Query 274 QHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTE--SRSP 321
+ + D +V ++R +E G+G WS+WS EA G + + S++P
Sbjct 260 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAP 309
>5njd_E E Interleukin-12 subunit beta
Length=328
Score = 53.9 bits (128), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 68/303 (22%), Positives = 116/303 (38%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 42 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 92
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 93 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 152
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 153 TFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEY----EYSVECQEDS---ACPAAEES 205
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + R + V+W+ P +W++
Sbjct 206 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLXXX-RQVEVSWEYPDTWST 264
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + D VI + +RAQ+ + WS
Sbjct 265 PHSYFSLTFCVQVQXXXXXXXXXRVFTDKTSATVI----CRKNASISVRAQDRYYSSSWS 320
Query 305 EWS 307
EW+
Sbjct 321 EWA 323
>8d6a_B A Interleukin-6 receptor subunit beta
Length=625
Score = 54.7 bits (130), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 55/213 (26%), Positives = 94/213 (44%), Gaps = 29/213 (14%)
Query 112 VPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAEDFQEPCQ 166
+PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 102 LPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-------- 152
Query 167 YSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQPDPPANI 222
+ SC + S+ Y V++ V +++G S F ++P+PP N+
Sbjct 153 --KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNL 206
Query 223 TVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL---QHHCVI 279
+V L +TW +P S L++ ++YR + + T++ +D + +
Sbjct 207 SVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV 264
Query 280 HDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMG 312
D +V ++R +E G+G WS+WS EA G
Sbjct 265 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 297
>8d7r_D A Interleukin-6 receptor subunit beta
Length=625
Score = 54.7 bits (130), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 55/213 (26%), Positives = 94/213 (44%), Gaps = 29/213 (14%)
Query 112 VPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAEDFQEPCQ 166
+PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 102 LPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-------- 152
Query 167 YSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQPDPPANI 222
+ SC + S+ Y V++ V +++G S F ++P+PP N+
Sbjct 153 --KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNL 206
Query 223 TVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL---QHHCVI 279
+V L +TW +P S L++ ++YR + + T++ +D + +
Sbjct 207 SVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV 264
Query 280 HDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMG 312
D +V ++R +E G+G WS+WS EA G
Sbjct 265 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 297
>8d74_A A Interleukin-6 receptor subunit beta
Length=625
Score = 54.7 bits (130), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 55/213 (26%), Positives = 94/213 (44%), Gaps = 29/213 (14%)
Query 112 VPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAEDFQEPCQ 166
+PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 102 LPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-------- 152
Query 167 YSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQPDPPANI 222
+ SC + S+ Y V++ V +++G S F ++P+PP N+
Sbjct 153 --KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNL 206
Query 223 TVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL---QHHCVI 279
+V L +TW +P S L++ ++YR + + T++ +D + +
Sbjct 207 SVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTV 264
Query 280 HDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMG 312
D +V ++R +E G+G WS+WS EA G
Sbjct 265 QDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 297
>5njd_C C Interleukin-12 subunit beta
Length=328
Score = 53.9 bits (128), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 67/303 (22%), Positives = 116/303 (38%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 42 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 92
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 93 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 152
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 153 TFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEY----EYSVECQEDS---ACPAAEES 205
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + + + V+W+ P +W++
Sbjct 206 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLXXXXQ-VEVSWEYPDTWST 264
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + D VI + +RAQ+ + WS
Sbjct 265 PHSYFSLTFCVQVQGXXXXXXXXRVFTDKTSATVI----CRKNASISVRAQDRYYSSSWS 320
Query 305 EWS 307
EW+
Sbjct 321 EWA 323
>8d85_D B Interleukin-6 receptor subunit beta
Length=625
Score = 54.3 bits (129), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 55/219 (25%), Positives = 97/219 (44%), Gaps = 29/219 (13%)
Query 106 VHLLVDVPPEEPQ-LSCFRKSPLSNVVCEW-GPRST---PSLTTKAVLLVRKFQNSPAED 160
+ ++ +PPE+P+ LSC + CEW G R T + T K+ KF + A
Sbjct 96 ITIISGLPPEKPKNLSCIVNEG-KKMRCEWDGGRETHLETNFTLKSEWATHKFADCKA-- 152
Query 161 FQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCV----ASSVGSKFSKTQTFQGCGILQP 216
+ SC + S+ Y V++ V +++G S F ++P
Sbjct 153 --------KRDTPTSCTVDY----STVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKP 200
Query 217 DPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL--- 273
+PP N++V L +TW +P S L++ ++YR + + T++ +D
Sbjct 201 NPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDTAST 258
Query 274 QHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMG 312
+ + D +V ++R +E G+G WS+WS EA G
Sbjct 259 RSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASG 297
>4grw_D D Interleukin-12 subunit beta
Length=328
Score = 53.5 bits (127), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 67/303 (22%), Positives = 116/303 (38%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 42 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 92
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 93 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 152
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 153 TFSVKSSRGSSDPQGVTCGAATLSAERVRXXNKEY----EYSVECQEDS---ACPAAEES 205
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + + + V+W+ P +W++
Sbjct 206 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLXXXXQ-VEVSWEYPDTWST 264
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + D VI + +RAQ+ + WS
Sbjct 265 PHSYFSLTFCVQVQGXXXXXXXDRVFTDKTSATVI----CRKNASISVRAQDRYYSSSWS 320
Query 305 EWS 307
EW+
Sbjct 321 EWA 323
>8qy6_F D Interleukin-6 receptor subunit beta
Length=917
Score = 53.9 bits (128), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 53/224 (24%), Positives = 99/224 (44%), Gaps = 21/224 (9%)
Query 106 VHLLVDVPPEEP-QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEP 164
V +L PP++P L+C N++C+W P L T L +E E
Sbjct 118 VTMLSGFPPDKPTNLTCIVNEG-KNMLCQWDPGRETYLETNYTL--------KSEWATEK 168
Query 165 CQYSQESQKFSCQLAVPEGDSSFYI---VSMCVASSVGSKFSKTQTFQGCGILQPDPPAN 221
Q SC ++ ++Y+ V + +++G S++ F ++P PP N
Sbjct 169 FPDCQSKHGTSCMVSYM---PTYYVNIEVWVEAENALGKVSSESINFDPVDKVKPTPPYN 225
Query 222 ITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL---QHHCV 278
++VT L ++W S L+ +++YR + + T+ ++D +
Sbjct 226 LSVTNSEELSSILKLSWVS--SGLGGLLDLKSDIQYRTKDASTWIQVPLEDTMSPRTSFT 283
Query 279 IHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTESRSPP 322
+ D +V ++R+ ++ G+G WS+WS EA GT + + S P
Sbjct 284 VQDLKPFTEYVFRIRSIKDSGKGYWSDWSEEASGTTYEDRPSRP 327
>8qy6_A A Interleukin-6 receptor subunit beta
Length=917
Score = 53.9 bits (128), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 53/224 (24%), Positives = 99/224 (44%), Gaps = 21/224 (9%)
Query 106 VHLLVDVPPEEP-QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEP 164
V +L PP++P L+C N++C+W P L T L +E E
Sbjct 118 VTMLSGFPPDKPTNLTCIVNEG-KNMLCQWDPGRETYLETNYTL--------KSEWATEK 168
Query 165 CQYSQESQKFSCQLAVPEGDSSFYI---VSMCVASSVGSKFSKTQTFQGCGILQPDPPAN 221
Q SC ++ ++Y+ V + +++G S++ F ++P PP N
Sbjct 169 FPDCQSKHGTSCMVSYM---PTYYVNIEVWVEAENALGKVSSESINFDPVDKVKPTPPYN 225
Query 222 ITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL---QHHCV 278
++VT L ++W S L+ +++YR + + T+ ++D +
Sbjct 226 LSVTNSEELSSILKLSWVS--SGLGGLLDLKSDIQYRTKDASTWIQVPLEDTMSPRTSFT 283
Query 279 IHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTESRSPP 322
+ D +V ++R+ ++ G+G WS+WS EA GT + + S P
Sbjct 284 VQDLKPFTEYVFRIRSIKDSGKGYWSDWSEEASGTTYEDRPSRP 327
>8qy5_F D Interleukin-6 receptor subunit beta
Length=917
Score = 53.9 bits (128), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 53/224 (24%), Positives = 99/224 (44%), Gaps = 21/224 (9%)
Query 106 VHLLVDVPPEEP-QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEP 164
V +L PP++P L+C N++C+W P L T L +E E
Sbjct 118 VTMLSGFPPDKPTNLTCIVNEG-KNMLCQWDPGRETYLETNYTL--------KSEWATEK 168
Query 165 CQYSQESQKFSCQLAVPEGDSSFYI---VSMCVASSVGSKFSKTQTFQGCGILQPDPPAN 221
Q SC ++ ++Y+ V + +++G S++ F ++P PP N
Sbjct 169 FPDCQSKHGTSCMVSYM---PTYYVNIEVWVEAENALGKVSSESINFDPVDKVKPTPPYN 225
Query 222 ITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL---QHHCV 278
++VT L ++W S L+ +++YR + + T+ ++D +
Sbjct 226 LSVTNSEELSSILKLSWVS--SGLGGLLDLKSDIQYRTKDASTWIQVPLEDTMSPRTSFT 283
Query 279 IHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTESRSPP 322
+ D +V ++R+ ++ G+G WS+WS EA GT + + S P
Sbjct 284 VQDLKPFTEYVFRIRSIKDSGKGYWSDWSEEASGTTYEDRPSRP 327
>8qy5_A A Interleukin-6 receptor subunit beta
Length=917
Score = 53.9 bits (128), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 53/224 (24%), Positives = 99/224 (44%), Gaps = 21/224 (9%)
Query 106 VHLLVDVPPEEP-QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEP 164
V +L PP++P L+C N++C+W P L T L +E E
Sbjct 118 VTMLSGFPPDKPTNLTCIVNEG-KNMLCQWDPGRETYLETNYTL--------KSEWATEK 168
Query 165 CQYSQESQKFSCQLAVPEGDSSFYI---VSMCVASSVGSKFSKTQTFQGCGILQPDPPAN 221
Q SC ++ ++Y+ V + +++G S++ F ++P PP N
Sbjct 169 FPDCQSKHGTSCMVSYM---PTYYVNIEVWVEAENALGKVSSESINFDPVDKVKPTPPYN 225
Query 222 ITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL---QHHCV 278
++VT L ++W S L+ +++YR + + T+ ++D +
Sbjct 226 LSVTNSEELSSILKLSWVS--SGLGGLLDLKSDIQYRTKDASTWIQVPLEDTMSPRTSFT 283
Query 279 IHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTESRSPP 322
+ D +V ++R+ ++ G+G WS+WS EA GT + + S P
Sbjct 284 VQDLKPFTEYVFRIRSIKDSGKGYWSDWSEEASGTTYEDRPSRP 327
>8qy4_B C Interleukin-6 receptor subunit beta
Length=917
Score = 53.5 bits (127), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 53/224 (24%), Positives = 99/224 (44%), Gaps = 21/224 (9%)
Query 106 VHLLVDVPPEEP-QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEP 164
V +L PP++P L+C N++C+W P L T L +E E
Sbjct 118 VTMLSGFPPDKPTNLTCIVNEG-KNMLCQWDPGRETYLETNYTL--------KSEWATEK 168
Query 165 CQYSQESQKFSCQLAVPEGDSSFYI---VSMCVASSVGSKFSKTQTFQGCGILQPDPPAN 221
Q SC ++ ++Y+ V + +++G S++ F ++P PP N
Sbjct 169 FPDCQSKHGTSCMVSYM---PTYYVNIEVWVEAENALGKVSSESINFDPVDKVKPTPPYN 225
Query 222 ITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL---QHHCV 278
++VT L ++W S L+ +++YR + + T+ ++D +
Sbjct 226 LSVTNSEELSSILKLSWVS--SGLGGLLDLKSDIQYRTKDASTWIQVPLEDTMSPRTSFT 283
Query 279 IHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTESRSPP 322
+ D +V ++R+ ++ G+G WS+WS EA GT + + S P
Sbjct 284 VQDLKPFTEYVFRIRSIKDSGKGYWSDWSEEASGTTYEDRPSRP 327
>8qy4_D F Interleukin-6 receptor subunit beta
Length=917
Score = 53.5 bits (127), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 53/224 (24%), Positives = 99/224 (44%), Gaps = 21/224 (9%)
Query 106 VHLLVDVPPEEP-QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEP 164
V +L PP++P L+C N++C+W P L T L +E E
Sbjct 118 VTMLSGFPPDKPTNLTCIVNEG-KNMLCQWDPGRETYLETNYTL--------KSEWATEK 168
Query 165 CQYSQESQKFSCQLAVPEGDSSFYI---VSMCVASSVGSKFSKTQTFQGCGILQPDPPAN 221
Q SC ++ ++Y+ V + +++G S++ F ++P PP N
Sbjct 169 FPDCQSKHGTSCMVSYM---PTYYVNIEVWVEAENALGKVSSESINFDPVDKVKPTPPYN 225
Query 222 ITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL---QHHCV 278
++VT L ++W S L+ +++YR + + T+ ++D +
Sbjct 226 LSVTNSEELSSILKLSWVS--SGLGGLLDLKSDIQYRTKDASTWIQVPLEDTMSPRTSFT 283
Query 279 IHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTESRSPP 322
+ D +V ++R+ ++ G+G WS+WS EA GT + + S P
Sbjct 284 VQDLKPFTEYVFRIRSIKDSGKGYWSDWSEEASGTTYEDRPSRP 327
>1f45_A A INTERLEUKIN-12 BETA CHAIN
Length=306
Score = 52.8 bits (125), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 68/303 (22%), Positives = 114/303 (38%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C
Sbjct 20 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCXX 70
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
+ +L D P + L C K+ C W
Sbjct 71 XXXXXSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 130
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + ++ +YS E Q+ S A P + S
Sbjct 131 TFSVKSSRGSSDPQGVTCGAATLSAEXXXXXXXEY----EYSVECQEDS---ACPAAEES 183
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + +N R + V+W+ P +W++
Sbjct 184 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTWST 242
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + D VI + +RAQ+ + WS
Sbjct 243 PHSYFSLTFCVQVQXXXXXXXKDRVFTDKTSATVI----CRXXXSISVRAQDRYYSSSWS 298
Query 305 EWS 307
EW+
Sbjct 299 EWA 301
>5njd_A A Interleukin-12 subunit beta
Length=328
Score = 52.8 bits (125), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 67/303 (22%), Positives = 116/303 (38%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 42 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 92
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 93 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 152
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 153 TFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEY----EYSVECQEDS---ACPAAEES 205
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + + + V+W+ P +W++
Sbjct 206 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKXXXQ-VEVSWEYPDTWST 264
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + D VI + +RAQ+ + WS
Sbjct 265 PHSYFSLTFCVQVQXXXXXEKKDRVFTDKTSATVI----CRKNASISVRAQDRYYSSSWS 320
Query 305 EWS 307
EW+
Sbjct 321 EWA 323
>5njd_I I Interleukin-12 subunit beta
Length=328
Score = 52.8 bits (125), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 67/303 (22%), Positives = 115/303 (38%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 42 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 92
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 93 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 152
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 153 TFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEY----EYSVECQEDS---ACPAAEES 205
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + + V+W+ P +W++
Sbjct 206 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPXXXXXQ-VEVSWEYPDTWST 264
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + D VI + +RAQ+ + WS
Sbjct 265 PHSYFSLTFCVQVQXXXXXXXXXRVFTDKTSATVI----CRKNASISVRAQDRYYSSSWS 320
Query 305 EWS 307
EW+
Sbjct 321 EWA 323
>5mj4_A A Interleukin-12 subunit beta
Length=306
Score = 52.4 bits (124), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 67/303 (22%), Positives = 115/303 (38%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 20 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 70
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 71 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 130
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + ++ +YS E Q+ S A P + S
Sbjct 131 TFSVKSSRGSSDPQGVTCGAATLSAERXXXXXXEY----EYSVECQEDS---ACPAAEES 183
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + + + V+W+ P +W++
Sbjct 184 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPL-KXXXXVEVSWEYPDTWST 242
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + D VI + +RAQ+ + WS
Sbjct 243 PHSYFSLTFCVQVQXXXXXXXKDRVFTDKTSATVI----CRKNASISVRAQDRYYSSSWS 298
Query 305 EWS 307
EW+
Sbjct 299 EWA 301
>5njd_G G Interleukin-12 subunit beta
Length=328
Score = 52.4 bits (124), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 67/303 (22%), Positives = 115/303 (38%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 42 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 92
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 93 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 152
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 153 TFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEY----EYSVECQEDS---ACPAAEES 205
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + + V+W+ P +W++
Sbjct 206 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPXXXXXQ-VEVSWEYPDTWST 264
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + D VI + +RAQ+ + WS
Sbjct 265 PHSYFSLTFCVQVQXXXXXXXKDRVFTDKTSATVI----CRKNASISVRAQDRYYSSSWS 320
Query 305 EWS 307
EW+
Sbjct 321 EWA 323
>5njd_K K Interleukin-12 subunit beta
Length=328
Score = 52.4 bits (124), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 68/303 (22%), Positives = 115/303 (38%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 42 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 92
Query 99 AGRPAG--------------TVHLLVD--VPPEEPQLSCFRKSPLSNVVCEW-------- 134
G + +L D P + L C K+ C W
Sbjct 93 GGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDL 152
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ +YS E Q+ S A P + S
Sbjct 153 TFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEY----EYSVECQEDS---ACPAAEES 205
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + R + V+W+ P +W++
Sbjct 206 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPXXXX-RQVEVSWEYPDTWST 264
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + D VI + +RAQ+ + WS
Sbjct 265 PHSYFSLTFCVQVQXXXXXEKKDRVFTDKTSATVI----CRKNASISVRAQDRYYSSSWS 320
Query 305 EWS 307
EW+
Sbjct 321 EWA 323
>7z0l_A A Interleukin-6 receptor subunit beta
Length=292
Score = 50.8 bits (120), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 51/215 (24%), Positives = 95/215 (44%), Gaps = 21/215 (10%)
Query 106 VHLLVDVPPEEP-QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEP 164
V +L PP++P L+C N++C+W P L T L +E E
Sbjct 91 VTMLSGFPPDKPTNLTCIVNEG-KNMLCQWDPGRETYLETNYTL--------KSEWATEK 141
Query 165 CQYSQESQKFSCQLAVPEGDSSFYI---VSMCVASSVGSKFSKTQTFQGCGILQPDPPAN 221
Q SC ++ ++Y+ V + +++G S++ F ++P PP N
Sbjct 142 FPDCQSKHGTSCMVSYM---PTYYVNIEVWVEAENALGKVSSESINFDPVDKVKPTPPYN 198
Query 222 ITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL---QHHCV 278
++VT L ++W S L+ +++YR + + T+ ++D +
Sbjct 199 LSVTNSEELSSILKLSWVS--SGLGGLLDLKSDIQYRTKDASTWIQVPLEDTMSPRTSFT 256
Query 279 IHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGT 313
+ D +V ++R+ ++ G+G WS+WS EA GT
Sbjct 257 VQDLKPFTEYVFRIRSIKDSGKGYWSDWSEEASGT 291
>3d85_D D Interleukin-12 subunit p40
Length=306
Score = 50.4 bits (119), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 66/303 (22%), Positives = 114/303 (38%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG+ V LTC PE++ + W L S G G+ L ++ + D+G Y+C++
Sbjct 20 PGEMVVLTCDT--PEEDG-ITWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHK 70
Query 99 AGRPAG--------------TVHLLVDVPPEEPQ--LSCFRKSPLSNVVCEW-------- 134
G + +L D + L C K+ C W
Sbjct 71 GGEVLSHSLLLLHKKEDGIWSTDILKDQKXXXNKTFLRCEAKNYSGRFTCWWLTTISTDL 130
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + ++++ YS E Q+ S A P + S
Sbjct 131 TFSVKSSRGSSDPQGVTCGAATLSAERVRXXNKEYE----YSVECQEDS---ACPAAEES 183
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A T +F I++PDPP N+ + + + + V+W+ P +W++
Sbjct 184 LPIEVMVDAVHKLKYEQYTSSFFIRDIIKPDPPKNLQLKPLXXXXQ-VEVSWEYPDTWST 242
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + D VI + +RAQ+ + WS
Sbjct 243 PHSYFSLTFCVQVQGXXXXXXKDRVFTDKTSATVI----CRKNASISVRAQDRYYSSSWS 298
Query 305 EWS 307
EW+
Sbjct 299 EWA 301
>1bj8_A A GP130
Length=109
Score = 46.6 bits (109), Expect = 3e-05, Method: Composition-based stats.
Identities = 28/107 (26%), Positives = 54/107 (50%), Gaps = 5/107 (5%)
Query 214 LQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDL 273
++P+PP N++V L +TW +P S L++ ++YR + + T++ +D
Sbjct 4 VKPNPPHNLSVINSEELSSILKLTWTNPSI--KSVIILKYNIQYRTKDASTWSQIPPEDT 61
Query 274 ---QHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTE 317
+ + D +V ++R +E G+G WS+WS EA G + +
Sbjct 62 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYED 108
>3ew3_B B Prolactin receptor
Length=221
Score = 48.1 bits (113), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 48/205 (23%), Positives = 83/205 (40%), Gaps = 16/205 (8%)
Query 113 PPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQ 172
PP +P++ R C W P + L T L K E C + S
Sbjct 4 PPGKPEIHKCRSPDKETFTCWWNPGTDGGLPTNYSLTYSK----EGEKTTYECPDYKTSG 59
Query 173 KFSCQLAVPEGDS-SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANIT--VTAVAR 229
SC + YI+++ + +GS S I++P+PP N+T V +
Sbjct 60 PNSCFFSKQYTSIWKIYIITVNATNQMGSSSSDPLYVDVTYIVEPEPPRNLTLEVKQLKD 119
Query 230 NPRWLSVTWQDP--HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHC--VIHDAWSG 285
+L V W P + ++ + +E+R + E ++ W + H + D + G
Sbjct 120 KKTYLWVKWSPPTITDVKTGWFTMEYEIRLKPEEAE---EWEIHFTGHQTQFKVFDLYPG 176
Query 286 LRHVVQLRAQEEFGQGEWSEWSPEA 310
+++VQ R + + G WS WS E+
Sbjct 177 QKYLVQTRCKPD--HGYWSRWSQES 199
>3npz_B B Prolactin receptor
Length=220
Score = 48.1 bits (113), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 48/205 (23%), Positives = 83/205 (40%), Gaps = 16/205 (8%)
Query 113 PPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQ 172
PP +P++ R C W P + L T L K E C + S
Sbjct 3 PPGKPEIHKCRSPDKETFTCWWNPGTDGGLPTNYSLTYSK----EGEKTTYECPDYKTSG 58
Query 173 KFSCQLAVPEGDS-SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANIT--VTAVAR 229
SC + YI+++ + +GS S I++P+PP N+T V +
Sbjct 59 PNSCFFSKQYTSIWKIYIITVNATNQMGSSSSDPLYVDVTYIVEPEPPRNLTLEVKQLKX 118
Query 230 NPRWLSVTWQDP--HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHC--VIHDAWSG 285
+L V W P + ++ + +E+R + E ++ W + H + D + G
Sbjct 119 XKTYLWVKWSPPTITDVKTGWFTMEYEIRLKPEEAE---EWEIHFTGHQTQFKVFDLYPG 175
Query 286 LRHVVQLRAQEEFGQGEWSEWSPEA 310
+++VQ R + + G WS WS E+
Sbjct 176 QKYLVQTRCKPD--HGYWSRWSQES 198
>3ncb_B B Prolactin receptor
Length=210
Score = 46.6 bits (109), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 47/202 (23%), Positives = 76/202 (38%), Gaps = 12/202 (6%)
Query 112 VPPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQES 171
+PP +P++ R C W P + L T L + E C
Sbjct 2 LPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHR----EGETLMHECPDYITG 57
Query 172 QKFSCQLAVPEGDS-SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARN 230
SC YI+ + + +GS FS I+QPDPP + V
Sbjct 58 GPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPE 117
Query 231 PR--WLSVTWQDPH--SWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL 286
R +L + W P + ++ L +E+R + E++ + Q I G
Sbjct 118 DRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEI-HFAGQQTEFKILSLHPGQ 176
Query 287 RHVVQLRAQEEFGQGEWSEWSP 308
+++VQ+R + + G WS WSP
Sbjct 177 KYLVQVRCKPD--HGYWSAWSP 196
>3n0p_B B Prolactin receptor
Length=210
Score = 46.6 bits (109), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 47/202 (23%), Positives = 76/202 (38%), Gaps = 12/202 (6%)
Query 112 VPPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQES 171
+PP +P++ R C W P + L T L + E C
Sbjct 2 LPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHR----EGETLMHECPDYITG 57
Query 172 QKFSCQLAVPEGDS-SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARN 230
SC YI+ + + +GS FS I+QPDPP + V
Sbjct 58 GPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPE 117
Query 231 PR--WLSVTWQDPH--SWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL 286
R +L + W P + ++ L +E+R + E++ + Q I G
Sbjct 118 DRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEI-HFAGQQTEFKILSLHPGQ 176
Query 287 RHVVQLRAQEEFGQGEWSEWSP 308
+++VQ+R + + G WS WSP
Sbjct 177 KYLVQVRCKPD--HGYWSAWSP 196
>3n06_B B Prolactin receptor
Length=210
Score = 46.6 bits (109), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 47/202 (23%), Positives = 76/202 (38%), Gaps = 12/202 (6%)
Query 112 VPPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQES 171
+PP +P++ R C W P + L T L + E C
Sbjct 2 LPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHR----EGETLMHECPDYITG 57
Query 172 QKFSCQLAVPEGDS-SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARN 230
SC YI+ + + +GS FS I+QPDPP + V
Sbjct 58 GPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPE 117
Query 231 PR--WLSVTWQDPH--SWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL 286
R +L + W P + ++ L +E+R + E++ + Q I G
Sbjct 118 DRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEI-HFAGQQTEFKILSLHPGQ 176
Query 287 RHVVQLRAQEEFGQGEWSEWSP 308
+++VQ+R + + G WS WSP
Sbjct 177 KYLVQVRCKPD--HGYWSAWSP 196
>3mzg_B B Prolactin receptor
Length=210
Score = 46.6 bits (109), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 47/202 (23%), Positives = 76/202 (38%), Gaps = 12/202 (6%)
Query 112 VPPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQES 171
+PP +P++ R C W P + L T L + E C
Sbjct 2 LPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHR----EGETLMHECPDYITG 57
Query 172 QKFSCQLAVPEGDS-SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARN 230
SC YI+ + + +GS FS I+QPDPP + V
Sbjct 58 GPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPE 117
Query 231 PR--WLSVTWQDPH--SWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL 286
R +L + W P + ++ L +E+R + E++ + Q I G
Sbjct 118 DRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEI-HFAGQQTEFKILSLHPGQ 176
Query 287 RHVVQLRAQEEFGQGEWSEWSP 308
+++VQ+R + + G WS WSP
Sbjct 177 KYLVQVRCKPD--HGYWSAWSP 196
>3npz_C C Prolactin receptor
Length=220
Score = 46.6 bits (109), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 48/205 (23%), Positives = 81/205 (40%), Gaps = 16/205 (8%)
Query 113 PPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQ 172
PP +P++ R C W P + L T L K E C + S
Sbjct 3 PPGKPEIHKCRSPDKETFTCWWNPGTDGGLPTNYSLTYSK----EGEKTTYECPDYKTSG 58
Query 173 KFSCQLAVPEGDS-SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANIT--VTAVAR 229
SC + YI+++ + +GS S I++P+PP N+T V
Sbjct 59 PNSCFFSKQYTSIWKIYIITVNATNQMGSSSSDPLYVDVTYIVEPEPPRNLTLEVKQXXX 118
Query 230 NPRWLSVTWQDP--HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHC--VIHDAWSG 285
+L V W P + ++ + +E+R + E + W + H + D + G
Sbjct 119 KKTYLWVKWSPPTITDVKTGWFTMEYEIRLKPEXXE---EWEIHFTGHQTQFKVFDLYPG 175
Query 286 LRHVVQLRAQEEFGQGEWSEWSPEA 310
+++VQ R + + G WS WS E+
Sbjct 176 QKYLVQTRCKPD--HGYWSRWSQES 198
>3nce_B B Prolactin receptor
Length=210
Score = 45.8 bits (107), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 47/202 (23%), Positives = 76/202 (38%), Gaps = 12/202 (6%)
Query 112 VPPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQES 171
+PP +P++ R C W P + L T L + E C
Sbjct 2 LPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHR----EGETLMHECPDYITG 57
Query 172 QKFSCQLAVPEGDS-SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARN 230
SC YI+ + + +GS FS I+QPDPP + V
Sbjct 58 GPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPE 117
Query 231 PR--WLSVTWQDPH--SWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL 286
R +L + W P + ++ L +E+R + E++ + Q I G
Sbjct 118 DRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEI-HFAGQQTEFKILSLHPGQ 176
Query 287 RHVVQLRAQEEFGQGEWSEWSP 308
+++VQ+R + + G WS WSP
Sbjct 177 KYLVQVRCKPD--AGYWSAWSP 196
>3ncc_B B Prolactin receptor
Length=210
Score = 45.8 bits (107), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 47/202 (23%), Positives = 76/202 (38%), Gaps = 12/202 (6%)
Query 112 VPPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQES 171
+PP +P++ R C W P + L T L + E C
Sbjct 2 LPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHR----EGETLMHECPDYITG 57
Query 172 QKFSCQLAVPEGDS-SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARN 230
SC YI+ + + +GS FS I+QPDPP + V
Sbjct 58 GPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPE 117
Query 231 PR--WLSVTWQDPH--SWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL 286
R +L + W P + ++ L +E+R + E++ + Q I G
Sbjct 118 DRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEI-HFAGQQTEFKILSLHPGQ 176
Query 287 RHVVQLRAQEEFGQGEWSEWSP 308
+++VQ+R + + G WS WSP
Sbjct 177 KYLVQVRCKPD--AGYWSAWSP 196
>3ncf_B B Prolactin receptor
Length=210
Score = 45.8 bits (107), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 47/202 (23%), Positives = 76/202 (38%), Gaps = 12/202 (6%)
Query 112 VPPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQES 171
+PP +P++ R C W P + L T L + E C
Sbjct 2 LPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHR----EGETLMHECPDYITG 57
Query 172 QKFSCQLAVPEGDS-SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARN 230
SC YI+ + + +GS FS I+QPDPP + V
Sbjct 58 GPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPE 117
Query 231 PR--WLSVTWQDPH--SWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL 286
R +L + W P + ++ L +E+R + E++ + Q I G
Sbjct 118 DRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEI-HFAGQQTEFKILSLHPGQ 176
Query 287 RHVVQLRAQEEFGQGEWSEWSP 308
+++VQ+R + + G WS WSP
Sbjct 177 KYLVQVRCKPD--AGYWSAWSP 196
>6uib_B B Interleukin-12 subunit beta
Length=316
Score = 46.2 bits (108), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 65/303 (21%), Positives = 112/303 (37%), Gaps = 55/303 (18%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCY- 97
PG+ V LTC + W L S G G+ L ++ + D+G Y+C+
Sbjct 24 PGEMVVLTC---DXXXXXXXXWTL------DQSSEVLGSGKTLTIQVKEFGDAGQYTCHX 74
Query 98 -------------RAGRPAGTVHLLVDVPPEEPQ--LSCFRKSPLSNVVCEW-------- 134
+ + +L D + L C K+ C W
Sbjct 75 XXXXXXHSLLLLHKKEDGIWSTDILKDQXXXXNKTFLRCEAKNYSGRFTCWWLTTISTDL 134
Query 135 --------GPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSS 186
G +T A L + +++ YS E Q+ S A P + S
Sbjct 135 TFSVKSSRGSSDPQGVTCGAATLSAERVXXXXXEYE----YSVECQEDS---ACPAAEES 187
Query 187 FYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS 246
I M A + T +F I++PDPP N+ + + +N R + V+W+ P +W++
Sbjct 188 LPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPL-KNSRQVEVSWEYPDTWST 246
Query 247 --SFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304
S++ L F ++ + + + D VI + +RAQ+ + WS
Sbjct 247 PHSYFSLTFCVQVQGKSKXXKKDRVFTDKTSATVI----CRKXXSISVRAQDRYYSSSWS 302
Query 305 EWS 307
EW+
Sbjct 303 EWA 305
>3d48_B R Prolactin receptor
Length=211
Score = 45.1 bits (105), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 46/202 (23%), Positives = 75/202 (37%), Gaps = 12/202 (6%)
Query 112 VPPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQES 171
+PP +P++ R C W P + L T L + E C
Sbjct 3 LPPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHR----EGETLMHECPDYITG 58
Query 172 QKFSCQLAVPEGDS-SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARN 230
SC YI+ + + +GS FS I+QPDPP + V
Sbjct 59 GPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKXXX 118
Query 231 PR--WLSVTWQDPH--SWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL 286
+L + W P + ++ L +E+R + E++ + Q I G
Sbjct 119 XXXPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEI-HFAGQQTEFKILSXXPGQ 177
Query 287 RHVVQLRAQEEFGQGEWSEWSP 308
+++VQ+R + + G WS WSP
Sbjct 178 KYLVQVRCKPD--HGYWSAWSP 197
>4i18_E R Prolactin receptor
Length=211
Score = 43.9 bits (102), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 46/201 (23%), Positives = 74/201 (37%), Gaps = 12/201 (6%)
Query 113 PPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQ 172
PP +P++ R C W P + T L + E C
Sbjct 3 PPGKPEIFKCRSPNKETFTCWWRPGTDGGXXTNYSLTYHR----EGETLMHECPDYITGG 58
Query 173 KFSCQLAVPEGDS-SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
SC YI+ + + +GS FS I+QPDPP + V
Sbjct 59 PNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPED 118
Query 232 R--WLSVTWQDPH--SWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLR 287
R +L + W P + ++ L +E+R + E++ + Q I G +
Sbjct 119 RKPYLWIKWSPPTLIXXKTGWFTLLYEIRLKPEKAAEWEI-HFAGQQTEFKILSLHPGQK 177
Query 288 HVVQLRAQEEFGQGEWSEWSP 308
++VQ+R + + G WS WSP
Sbjct 178 YLVQVRCKPD--HGYWSAWSP 196
>7u7n_C C Interleukin-27 subunit beta
Length=208
Score = 43.9 bits (102), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 51/200 (26%), Positives = 82/200 (41%), Gaps = 9/200 (5%)
Query 117 PQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSC 176
P++ C V C W P+ T+ + A PC Q SC
Sbjct 11 PRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPC-LQQTPTSTSC 69
Query 177 QLA-VPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLS 235
+ V + Y++++ GS S F I++PDPP + ++ +A R L
Sbjct 70 TITDVQLFSMAPYVLNVTAVHPWGSS-SSFVPFITEHIIKPDPPEGVRLSPLAE--RQLQ 126
Query 236 VTWQDPHSW-NSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWS-GLRHVVQLR 293
V W+ P SW + L++ +RY+ + + F V ++ I A R+ VQ+
Sbjct 127 VQWEPPGSWPFPEIFSLKYWIRYKRQGAARFH--RVGPIEATSFILRAVRPRARYYVQVA 184
Query 294 AQEEFGQGEWSEWSPEAMGT 313
AQ+ GE S+WS A T
Sbjct 185 AQDLTDYGELSDWSLPATAT 204
>8d85_A C Interleukin-27 subunit beta
Length=209
Score = 43.9 bits (102), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 51/200 (26%), Positives = 82/200 (41%), Gaps = 9/200 (5%)
Query 117 PQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSC 176
P++ C V C W P+ T+ + A PC Q SC
Sbjct 11 PRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPC-LQQTPTSTSC 69
Query 177 QLA-VPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLS 235
+ V + Y++++ GS S F I++PDPP + ++ +A R L
Sbjct 70 TITDVQLFSMAPYVLNVTAVHPWGSS-SSFVPFITEHIIKPDPPEGVRLSPLAE--RQLQ 126
Query 236 VTWQDPHSW-NSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWS-GLRHVVQLR 293
V W+ P SW + L++ +RY+ + + F V ++ I A R+ VQ+
Sbjct 127 VQWEPPGSWPFPEIFSLKYWIRYKRQGAARFH--RVGPIEATSFILRAVRPRARYYVQVA 184
Query 294 AQEEFGQGEWSEWSPEAMGT 313
AQ+ GE S+WS A T
Sbjct 185 AQDLTDYGELSDWSLPATAT 204
>1f6f_B B PROLACTIN RECEPTOR
Length=210
Score = 43.5 bits (101), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 46/202 (23%), Positives = 80/202 (40%), Gaps = 16/202 (8%)
Query 116 EPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFS 175
+P++ R C W P + L T L K E C + S S
Sbjct 6 KPEIHKCRSPDKETFTCWWNPGTDGGLPTNYSLTYSK----EGEKTTYECPDYKTSGPNS 61
Query 176 CQLAVPEGDS-SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANIT--VTAVARNPR 232
C + YI+++ + +GS S I++P+PP N+T V
Sbjct 62 CFFSKQYTSIWKIYIITVNATNQMGSSSSDPLYVDVTYIVEPEPPRNLTLEVKXXXXKKT 121
Query 233 WLSVTWQDP--HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHC--VIHDAWSGLRH 288
+L V W P + ++ + +E+R + E ++ W + H + D + G ++
Sbjct 122 YLWVKWSPPTITDVKTGWFTMEYEIRLKPEEAE---EWEIHFTGHQTQFKVFDLYPGQKY 178
Query 289 VVQLRAQEEFGQGEWSEWSPEA 310
+VQ R + + G WS WS E+
Sbjct 179 LVQTRCKPD--HGYWSRWSQES 198
>8odz_D D Interleukin-12 receptor subunit beta-2,Calmodulin-1
Length=769
Score = 44.7 bits (104), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 46/210 (22%), Positives = 79/210 (38%), Gaps = 13/210 (6%)
Query 102 PAGTVHLLVDVPPEEPQ-LSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAED 160
P V + V V PE PQ +SC ++ V C W L T L + N
Sbjct 102 PVCGVEISVGVAPEPPQNISCVQEGENGTVACSWNSGKVTYLKTNYTLQLSGPNNLTC-- 159
Query 161 FQEPCQYSQESQKFSCQLAV---PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPD 217
Q+ C L + P+ S +IV + + +G+ S TF I+ P
Sbjct 160 -QKQCFSDNRQNCNRLDLGINLSPDLAESRFIVRVTAINDLGNSSSLPHTFTFLDIVIPL 218
Query 218 PPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHC 277
PP +I + + + ++ W+D + +LRY+ S ++ + +
Sbjct 219 PPWDIRINFLNASGSRGTLQWEDEGQ------VVLNQLRYQPLNSTSWNMVNATNAKGKY 272
Query 278 VIHDAWSGLRHVVQLRAQEEFGQGEWSEWS 307
+ D + Q+ ++ G WS WS
Sbjct 273 DLRDLRPFTEYEFQISSKLHLSGGSWSNWS 302
>8oe0_D D Interleukin-12 receptor subunit beta-2,Calmodulin-1
Length=769
Score = 44.7 bits (104), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 46/210 (22%), Positives = 79/210 (38%), Gaps = 13/210 (6%)
Query 102 PAGTVHLLVDVPPEEPQ-LSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAED 160
P V + V V PE PQ +SC ++ V C W L T L + N
Sbjct 102 PVCGVEISVGVAPEPPQNISCVQEGENGTVACSWNSGKVTYLKTNYTLQLSGPNNLTC-- 159
Query 161 FQEPCQYSQESQKFSCQLAV---PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPD 217
Q+ C L + P+ S +IV + + +G+ S TF I+ P
Sbjct 160 -QKQCFSDNRQNCNRLDLGINLSPDLAESRFIVRVTAINDLGNSSSLPHTFTFLDIVIPL 218
Query 218 PPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHC 277
PP +I + + + ++ W+D + +LRY+ S ++ + +
Sbjct 219 PPWDIRINFLNASGSRGTLQWEDEGQ------VVLNQLRYQPLNSTSWNMVNATNAKGKY 272
Query 278 VIHDAWSGLRHVVQLRAQEEFGQGEWSEWS 307
+ D + Q+ ++ G WS WS
Sbjct 273 DLRDLRPFTEYEFQISSKLHLSGGSWSNWS 302
>7z3p_B B Leptin receptor
Length=232
Score = 43.1 bits (100), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 81/200 (41%), Gaps = 10/200 (5%)
Query 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAED------FQEPCQYSQES 171
+SC L+ + C W P + SL V L ++ D EP +
Sbjct 30 NISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDSPSIHPTSEPKNCVLQR 89
Query 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
F + P S Y + + + S+GS S +++P PP+N+ + N
Sbjct 90 DGFYECVFQPIFLLSGYTMWIRIQHSLGSLDSPPTCVLPDSVVKPLPPSNVK-AEITVNT 148
Query 232 RWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290
L V+W+ P N+ +++R+ L + + KT + K ++ D +VV
Sbjct 149 GLLKVSWEKPVFPENNLQFQIRYGLSGKEIQWKTHEVFDAKSKSASLLVSDL--SAVYVV 206
Query 291 QLRAQEEFGQGEWSEWSPEA 310
Q+R + G G WS WS A
Sbjct 207 QVRCRRLDGLGYWSNWSSPA 226
>8dha_B B Leptin receptor
Length=555
Score = 43.1 bits (100), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 10/200 (5%)
Query 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAED------FQEPCQYSQES 171
+SC L+ + C W P + SL V L ++ D EP +
Sbjct 102 NISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDSPSIHPTSEPKNCVLQR 161
Query 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
F + P S Y + + + S+GS S +++P PP+N+ + N
Sbjct 162 DGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVK-AEITVNT 220
Query 232 RWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290
L V+W+ P N+ +++R+ L + + KT + K ++ D + +VV
Sbjct 221 GLLKVSWEKPVFPENNLQFQIRYGLSGKEIQWKTHEVFDAKSKSASLLVSDLCA--VYVV 278
Query 291 QLRAQEEFGQGEWSEWSPEA 310
Q+R + G G WS WS A
Sbjct 279 QVRCRRLDGLGYWSNWSSPA 298
>4i18_F C Prolactin receptor
Length=211
Score = 42.0 bits (97), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 45/201 (22%), Positives = 73/201 (36%), Gaps = 12/201 (6%)
Query 113 PPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQ 172
PP +P++ R C W P + L T L + E C
Sbjct 3 PPGKPEIFKCRSPNKETFTCWWRPGTDGGLPTNYSLTYHR----EGETLMHECPDYITGG 58
Query 173 KFSCQLAVPEGDS-SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
SC YI+ + + +GS FS I+QPDPP + V
Sbjct 59 PNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKXXXX 118
Query 232 R--WLSVTWQDPH--SWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLR 287
+L + W P + ++ L +E+R + E++ + Q I +
Sbjct 119 XXPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEI-HFAGQQTEFKILSXXXXXK 177
Query 288 HVVQLRAQEEFGQGEWSEWSP 308
++VQ+R + + G WS WSP
Sbjct 178 YLVQVRCKPD--HGYWSAWSP 196
>7zxk_B B Interleukin-27 subunit beta
Length=209
Score = 42.0 bits (97), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 6/103 (6%)
Query 213 ILQPDPPANITVTAVARNPRWLSVTWQDPHSW-NSSFYRLRFELRYRAERSKTFTTWMVK 271
I++PDPP + ++ +A R L V W+ P SW + L++ +RY+ + + F V
Sbjct 106 IIKPDPPEGVRLSPLAE--RQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHR--VG 161
Query 272 DLQHHCVIHDAWS-GLRHVVQLRAQEEFGQGEWSEWSPEAMGT 313
++ I A R+ VQ+ AQ+ GE S+WS A T
Sbjct 162 PIEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATAT 204
>7zxk_D D Interleukin-27 subunit beta
Length=209
Score = 42.0 bits (97), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 6/103 (6%)
Query 213 ILQPDPPANITVTAVARNPRWLSVTWQDPHSW-NSSFYRLRFELRYRAERSKTFTTWMVK 271
I++PDPP + ++ +A R L V W+ P SW + L++ +RY+ + + F V
Sbjct 106 IIKPDPPEGVRLSPLAE--RQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHR--VG 161
Query 272 DLQHHCVIHDAWS-GLRHVVQLRAQEEFGQGEWSEWSPEAMGT 313
++ I A R+ VQ+ AQ+ GE S+WS A T
Sbjct 162 PIEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATAT 204
>8b7q_B B Leptin receptor
Length=868
Score = 43.1 bits (100), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 10/200 (5%)
Query 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAED------FQEPCQYSQES 171
+SC L+ + C W P + SL V L ++ D EP +
Sbjct 410 NISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDSPSIHPTSEPKNCVLQR 469
Query 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
F + P S Y + + + S+GS S +++P PP+N+ + N
Sbjct 470 DGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVK-AEITVNT 528
Query 232 RWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290
L V+W+ P N+ +++R+ L + + KT + K ++ D + +VV
Sbjct 529 GLLKVSWEKPVFPENNLQFQIRYGLSGKEIQWKTHEVFDAKSKSASLLVSDLCA--VYVV 586
Query 291 QLRAQEEFGQGEWSEWSPEA 310
Q+R + G G WS WS A
Sbjct 587 QVRCRRLDGLGYWSNWSSPA 606
>6sff_A A Interleukin-12 subunit beta
Length=344
Score = 42.4 bits (98), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 55/243 (23%), Positives = 93/243 (38%), Gaps = 36/243 (15%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG++V LTC E ED+ T R GS G+ L + + D+G Y+C++
Sbjct 42 PGETVNLTCDTPE-EDDITWTSDQRHGVIGS--------GKTLTITVKEFLDAGQYTCHK 92
Query 99 AGRPAGTVHLLVDVP-------------PEEPQLSCFRKSPLSNVVCEWGPRSTPSL--- 142
G HLL+ + L C + C W + L
Sbjct 93 GGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFN 152
Query 143 --TTKAVLLVRKFQNSPAEDFQEPCQYSQ---ESQKFSCQ--LAVPEGDSSFYIVSMCVA 195
++ + R A E Q E SCQ + P + + I A
Sbjct 153 IKSSSSXXDSRAVTCGMASLSAEKVTLDQRDYEKYSVSCQEDVTCPTAEETLPIELALEA 212
Query 196 SSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS--SFYRLRF 253
+ + +F I++PDPP N+ + + + + V+W+ P SW++ S++ L+F
Sbjct 213 RQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLKXSQ--VEVSWEYPDSWSTPHSYFSLKF 270
Query 254 ELR 256
+R
Sbjct 271 FVR 273
>7r3n_D D Interleukin-12 subunit beta
Length=335
Score = 42.4 bits (98), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 54/251 (22%), Positives = 96/251 (38%), Gaps = 42/251 (17%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG++V LTC E ED+ T R GS G+ L + + D+G Y+C++
Sbjct 42 PGETVNLTCDTPE-EDDITWTSDQRHGVIGS--------GKTLTITVKEFLDAGQYTCHK 92
Query 99 AGRPAGTVHLLVDVP-------------PEEPQLSCFRKSPLSNVVCEWGPRSTPSLT-- 143
G HLL+ + L C + C W + L
Sbjct 93 GGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFN 152
Query 144 ---------TKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQ--LAVPEGDSSFYIVSM 192
++AV ++ Q E SCQ + P + + I
Sbjct 153 IKSSSSSPDSRAVTCGMASLSAEKVTLD---QRDYEKYSVSCQEDVTCPTAEETLPIELA 209
Query 193 CVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS--SFYR 250
A + + +F I++PDPP N+ + + + + V+W+ P SW++ S++
Sbjct 210 LEARQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLKNSQ--VEVSWEYPDSWSTPHSYFS 267
Query 251 LRFELRYRAER 261
L+F +R + ++
Sbjct 268 LKFFVRIQRKK 278
>8pb1_B B Interleukin-12 subunit beta
Length=313
Score = 42.4 bits (98), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 55/243 (23%), Positives = 90/243 (37%), Gaps = 36/243 (15%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG++V LTC E ED+ T R GS G+ L + + D+G Y+C++
Sbjct 20 PGETVNLTCDTPE-EDDITWTSDQRHGVIGS--------GKTLTITVKEFLDAGQYTCHK 70
Query 99 AGRPAGTVHLLVDVP-------------PEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTK 145
G HLL+ + L C + C W + L
Sbjct 71 GGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFN 130
Query 146 AVLLV-----RKFQNSPAEDFQEPCQYSQ---ESQKFSCQ--LAVPEGDSSFYIVSMCVA 195
R A E Q E SCQ + P + + I A
Sbjct 131 IKSSSSSPDSRAVTCGMASLSAEKVTLDQRDYEKYSVSCQEDVTCPTAEETLPIELALEA 190
Query 196 SSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS--SFYRLRF 253
+ + +F I++PDPP N+ + + + + V+W+ P SW++ S++ L+F
Sbjct 191 RQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLKNSQ--VEVSWEYPDSWSTPHSYFSLKF 248
Query 254 ELR 256
+R
Sbjct 249 FVR 251
>8odz_B B Interleukin-12 subunit beta
Length=313
Score = 42.4 bits (98), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 55/243 (23%), Positives = 90/243 (37%), Gaps = 36/243 (15%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG++V LTC E ED+ T R GS G+ L + + D+G Y+C++
Sbjct 20 PGETVNLTCDTPE-EDDITWTSDQRHGVIGS--------GKTLTITVKEFLDAGQYTCHK 70
Query 99 AGRPAGTVHLLVDVP-------------PEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTK 145
G HLL+ + L C + C W + L
Sbjct 71 GGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFN 130
Query 146 AVLLV-----RKFQNSPAEDFQEPCQYSQ---ESQKFSCQ--LAVPEGDSSFYIVSMCVA 195
R A E Q E SCQ + P + + I A
Sbjct 131 IKSSSSSPDSRAVTCGMASLSAEKVTLDQRDYEKYSVSCQEDVTCPTAEETLPIELALEA 190
Query 196 SSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS--SFYRLRF 253
+ + +F I++PDPP N+ + + + + V+W+ P SW++ S++ L+F
Sbjct 191 RQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLKNSQ--VEVSWEYPDSWSTPHSYFSLKF 248
Query 254 ELR 256
+R
Sbjct 249 FVR 251
>7pur_A A Interleukin-12 subunit beta
Length=344
Score = 42.4 bits (98), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 55/243 (23%), Positives = 90/243 (37%), Gaps = 36/243 (15%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG++V LTC E ED+ T R GS G+ L + + D+G Y+C++
Sbjct 42 PGETVNLTCDTPE-EDDITWTSDQRHGVIGS--------GKTLTITVKEFLDAGQYTCHK 92
Query 99 AGRPAGTVHLLVDVP-------------PEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTK 145
G HLL+ + L C + C W + L
Sbjct 93 GGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFN 152
Query 146 AVLLV-----RKFQNSPAEDFQEPCQYSQ---ESQKFSCQ--LAVPEGDSSFYIVSMCVA 195
R A E Q E SCQ + P + + I A
Sbjct 153 IKSSSSSPDSRAVTCGMASLSAEKVTLDQRDYEKYSVSCQEDVTCPTAEETLPIELALEA 212
Query 196 SSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS--SFYRLRF 253
+ + +F I++PDPP N+ + + + + V+W+ P SW++ S++ L+F
Sbjct 213 RQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLKNSQ--VEVSWEYPDSWSTPHSYFSLKF 270
Query 254 ELR 256
+R
Sbjct 271 FVR 273
>6sp3_B B Interleukin-12 subunit beta
Length=344
Score = 42.0 bits (97), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 54/246 (22%), Positives = 93/246 (38%), Gaps = 42/246 (17%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG++V LTC E ED+ T R GS G+ L + + D+G Y+C++
Sbjct 42 PGETVNLTCDTPE-EDDITWTSDQRHGVIGS--------GKTLTITVKEFLDAGQYTCHK 92
Query 99 AGRPAGTVHLLVDVP-------------PEEPQLSCFRKSPLSNVVCEWGPRSTPSLT-- 143
G HLL+ + L C + C W + L
Sbjct 93 GGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFN 152
Query 144 ---------TKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQ--LAVPEGDSSFYIVSM 192
++AV ++ Q E SCQ + P + + I
Sbjct 153 IKSSSSSPDSRAVTCGMASLSAEKVTLD---QRDYEKYSVSCQEDVTCPTAEETLPIELA 209
Query 193 CVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS--SFYR 250
A + + +F I++PDPP N+ + + + + V+W+ P SW++ S++
Sbjct 210 LEARQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLKNSQ--VEVSWEYPDSWSTPHSYFS 267
Query 251 LRFELR 256
L+F +R
Sbjct 268 LKFFVR 273
>7r3n_B B Interleukin-12 subunit beta
Length=335
Score = 42.0 bits (97), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 54/246 (22%), Positives = 93/246 (38%), Gaps = 42/246 (17%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG++V LTC E ED+ T R GS G+ L + + D+G Y+C++
Sbjct 42 PGETVNLTCDTPE-EDDITWTSDQRHGVIGS--------GKTLTITVKEFLDAGQYTCHK 92
Query 99 AGRPAGTVHLLVDVP-------------PEEPQLSCFRKSPLSNVVCEWGPRSTPSLT-- 143
G HLL+ + L C + C W + L
Sbjct 93 GGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFN 152
Query 144 ---------TKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQ--LAVPEGDSSFYIVSM 192
++AV ++ Q E SCQ + P + + I
Sbjct 153 IKSSSSSPDSRAVTCGMASLSAEKVTLD---QRDYEKYSVSCQEDVTCPTAEETLPIELA 209
Query 193 CVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS--SFYR 250
A + + +F I++PDPP N+ + + + + V+W+ P SW++ S++
Sbjct 210 LEARQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLKNSQ--VEVSWEYPDSWSTPHSYFS 267
Query 251 LRFELR 256
L+F +R
Sbjct 268 LKFFVR 273
>6smc_B B Interleukin-12 subunit beta
Length=344
Score = 42.0 bits (97), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 54/246 (22%), Positives = 93/246 (38%), Gaps = 42/246 (17%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG++V LTC E ED+ T R GS G+ L + + D+G Y+C++
Sbjct 42 PGETVNLTCDTPE-EDDITWTSDQRHGVIGS--------GKTLTITVKEFLDAGQYTCHK 92
Query 99 AGRPAGTVHLLVDVP-------------PEEPQLSCFRKSPLSNVVCEWGPRSTPSLT-- 143
G HLL+ + L C + C W + L
Sbjct 93 GGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFN 152
Query 144 ---------TKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQ--LAVPEGDSSFYIVSM 192
++AV ++ Q E SCQ + P + + I
Sbjct 153 IKSSSSSPDSRAVTCGMASLSAEKVTLD---QRDYEKYSVSCQEDVTCPTAEETLPIELA 209
Query 193 CVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS--SFYR 250
A + + +F I++PDPP N+ + + + + V+W+ P SW++ S++
Sbjct 210 LEARQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLKNSQ--VEVSWEYPDSWSTPHSYFS 267
Query 251 LRFELR 256
L+F +R
Sbjct 268 LKFFVR 273
>6smc_A A Interleukin-12 subunit beta
Length=344
Score = 42.0 bits (97), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 54/246 (22%), Positives = 93/246 (38%), Gaps = 42/246 (17%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG++V LTC E ED+ T R GS G+ L + + D+G Y+C++
Sbjct 42 PGETVNLTCDTPE-EDDITWTSDQRHGVIGS--------GKTLTITVKEFLDAGQYTCHK 92
Query 99 AGRPAGTVHLLVDVP-------------PEEPQLSCFRKSPLSNVVCEWGPRSTPSLT-- 143
G HLL+ + L C + C W + L
Sbjct 93 GGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFN 152
Query 144 ---------TKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQ--LAVPEGDSSFYIVSM 192
++AV ++ Q E SCQ + P + + I
Sbjct 153 IKSSSSSPDSRAVTCGMASLSAEKVTLD---QRDYEKYSVSCQEDVTCPTAEETLPIELA 209
Query 193 CVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS--SFYR 250
A + + +F I++PDPP N+ + + + + V+W+ P SW++ S++
Sbjct 210 LEARQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLKNSQ--VEVSWEYPDSWSTPHSYFS 267
Query 251 LRFELR 256
L+F +R
Sbjct 268 LKFFVR 273
>6smc_C C Interleukin-12 subunit beta
Length=344
Score = 42.0 bits (97), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 54/246 (22%), Positives = 93/246 (38%), Gaps = 42/246 (17%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG++V LTC E ED+ T R GS G+ L + + D+G Y+C++
Sbjct 42 PGETVNLTCDTPE-EDDITWTSDQRHGVIGS--------GKTLTITVKEFLDAGQYTCHK 92
Query 99 AGRPAGTVHLLVDVP-------------PEEPQLSCFRKSPLSNVVCEWGPRSTPSLT-- 143
G HLL+ + L C + C W + L
Sbjct 93 GGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFN 152
Query 144 ---------TKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQ--LAVPEGDSSFYIVSM 192
++AV ++ Q E SCQ + P + + I
Sbjct 153 IKSSSSSPDSRAVTCGMASLSAEKVTLD---QRDYEKYSVSCQEDVTCPTAEETLPIELA 209
Query 193 CVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS--SFYR 250
A + + +F I++PDPP N+ + + + + V+W+ P SW++ S++
Sbjct 210 LEARQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLKNSQ--VEVSWEYPDSWSTPHSYFS 267
Query 251 LRFELR 256
L+F +R
Sbjct 268 LKFFVR 273
>7r3n_C C Interleukin-12 subunit beta
Length=335
Score = 42.0 bits (97), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 54/246 (22%), Positives = 93/246 (38%), Gaps = 42/246 (17%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG++V LTC E ED+ T R GS G+ L + + D+G Y+C++
Sbjct 42 PGETVNLTCDTPE-EDDITWTSDQRHGVIGS--------GKTLTITVKEFLDAGQYTCHK 92
Query 99 AGRPAGTVHLLVDVP-------------PEEPQLSCFRKSPLSNVVCEWGPRSTPSLT-- 143
G HLL+ + L C + C W + L
Sbjct 93 GGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFN 152
Query 144 ---------TKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQ--LAVPEGDSSFYIVSM 192
++AV ++ Q E SCQ + P + + I
Sbjct 153 IKSSSSSPDSRAVTCGMASLSAEKVTLD---QRDYEKYSVSCQEDVTCPTAEETLPIELA 209
Query 193 CVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS--SFYR 250
A + + +F I++PDPP N+ + + + + V+W+ P SW++ S++
Sbjct 210 LEARQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLKNSQ--VEVSWEYPDSWSTPHSYFS 267
Query 251 LRFELR 256
L+F +R
Sbjct 268 LKFFVR 273
>7r3n_A A Interleukin-12 subunit beta
Length=335
Score = 42.0 bits (97), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 54/246 (22%), Positives = 93/246 (38%), Gaps = 42/246 (17%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG++V LTC E ED+ T R GS G+ L + + D+G Y+C++
Sbjct 42 PGETVNLTCDTPE-EDDITWTSDQRHGVIGS--------GKTLTITVKEFLDAGQYTCHK 92
Query 99 AGRPAGTVHLLVDVP-------------PEEPQLSCFRKSPLSNVVCEWGPRSTPSLT-- 143
G HLL+ + L C + C W + L
Sbjct 93 GGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFN 152
Query 144 ---------TKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQ--LAVPEGDSSFYIVSM 192
++AV ++ Q E SCQ + P + + I
Sbjct 153 IKSSSSSPDSRAVTCGMASLSAEKVTLD---QRDYEKYSVSCQEDVTCPTAEETLPIELA 209
Query 193 CVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS--SFYR 250
A + + +F I++PDPP N+ + + + + V+W+ P SW++ S++
Sbjct 210 LEARQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLKNSQ--VEVSWEYPDSWSTPHSYFS 267
Query 251 LRFELR 256
L+F +R
Sbjct 268 LKFFVR 273
>8oe0_B B Interleukin-12 subunit beta
Length=313
Score = 41.6 bits (96), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 55/243 (23%), Positives = 90/243 (37%), Gaps = 36/243 (15%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG++V LTC E ED+ T R GS G+ L + + D+G Y+C++
Sbjct 20 PGETVNLTCDTPE-EDDITWTSDQRHGVIGS--------GKTLTITVKEFLDAGQYTCHK 70
Query 99 AGRPAGTVHLLVDVP-------------PEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTK 145
G HLL+ + L C + C W + L
Sbjct 71 GGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFN 130
Query 146 AVLLV-----RKFQNSPAEDFQEPCQYSQ---ESQKFSCQ--LAVPEGDSSFYIVSMCVA 195
R A E Q E SCQ + P + + I A
Sbjct 131 IKSSSSSPDSRAVTCGMASLSAEKVTLDQRDYEKYSVSCQEDVTCPTAEETLPIELALEA 190
Query 196 SSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS--SFYRLRF 253
+ + +F I++PDPP N+ + + + + V+W+ P SW++ S++ L+F
Sbjct 191 RQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLXXSQ--VEVSWEYPDSWSTPHSYFSLKF 248
Query 254 ELR 256
+R
Sbjct 249 FVR 251
>8cr5_A A Interleukin-12 subunit beta
Length=344
Score = 42.0 bits (97), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 56/243 (23%), Positives = 91/243 (37%), Gaps = 36/243 (15%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG++V LTC E ED+ T R GS G+ L + + D+G Y+C++
Sbjct 42 PGETVNLTCDTPE-EDDITWTSDQRHGVIGS--------GKTLTITVKEFLDAGQYTCHK 92
Query 99 AGRPAGTVHLLVDVP-------------PEEPQLSCFRKSPLSNVVCEWGPRSTPSL--- 142
G HLL+ + L C + C W + L
Sbjct 93 GGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFN 152
Query 143 --TTKAVLLVRKFQNSPAEDFQEPCQYSQ---ESQKFSCQLAV--PEGDSSFYIVSMCVA 195
++ R A E Q E SCQ V P + + I A
Sbjct 153 IKSSXXXXDSRAVTCGMASLSAEKVTLDQRDYEKYSVSCQEDVTSPTAEETLPIELALEA 212
Query 196 SSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS--SFYRLRF 253
+ + +F I++PDPP N+ + + + V+W+ P SW++ S++ L+F
Sbjct 213 RQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLKXXQ--VEVSWEYPDSWSTPHSYFSLKF 270
Query 254 ELR 256
+R
Sbjct 271 FVR 273
>6sp3_A A Interleukin-12 subunit beta
Length=344
Score = 42.0 bits (97), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 55/243 (23%), Positives = 90/243 (37%), Gaps = 36/243 (15%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG++V LTC E ED+ T R GS G+ L + + D+G Y+C++
Sbjct 42 PGETVNLTCDTPE-EDDITWTSDQRHGVIGS--------GKTLTITVKEFLDAGQYTCHK 92
Query 99 AGRPAGTVHLLVDVP-------------PEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTK 145
G HLL+ + L C + C W + L
Sbjct 93 GGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFN 152
Query 146 AVLLV-----RKFQNSPAEDFQEPCQYSQ---ESQKFSCQ--LAVPEGDSSFYIVSMCVA 195
R A E Q E SCQ + P + + I A
Sbjct 153 IKSSSSSPDSRAVTCGMASLSAEKVTLDQRDYEKYSVSCQEDVTCPTAEETLPIELALEA 212
Query 196 SSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS--SFYRLRF 253
+ + +F I++PDPP N+ + + + + V+W+ P SW++ S++ L+F
Sbjct 213 RQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLKNSQ--VEVSWEYPDSWSTPHSYFSLKF 270
Query 254 ELR 256
+R
Sbjct 271 FVR 273
>7pur_B B Interleukin-12 subunit beta
Length=344
Score = 42.0 bits (97), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 55/243 (23%), Positives = 90/243 (37%), Gaps = 36/243 (15%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG++V LTC E ED+ T R GS G+ L + + D+G Y+C++
Sbjct 42 PGETVNLTCDTPE-EDDITWTSDQRHGVIGS--------GKTLTITVKEFLDAGQYTCHK 92
Query 99 AGRPAGTVHLLVDVP-------------PEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTK 145
G HLL+ + L C + C W + L
Sbjct 93 GGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFN 152
Query 146 AVLLV-----RKFQNSPAEDFQEPCQYSQ---ESQKFSCQ--LAVPEGDSSFYIVSMCVA 195
R A E Q E SCQ + P + + I A
Sbjct 153 IKSSSSSPDSRAVTCGMASLSAEKVTLDQRDYEKYSVSCQEDVTCPTAEETLPIELALEA 212
Query 196 SSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS--SFYRLRF 253
+ + +F I++PDPP N+ + + + + V+W+ P SW++ S++ L+F
Sbjct 213 RQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLKNSQ--VEVSWEYPDSWSTPHSYFSLKF 270
Query 254 ELR 256
+R
Sbjct 271 FVR 273
>8dh8_A A Leptin receptor
Length=863
Score = 42.0 bits (97), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 10/200 (5%)
Query 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAED------FQEPCQYSQES 171
+SC L+ + C W P + SL V L ++ D EP +
Sbjct 410 NISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDSPSIHPTSEPKNCVLQR 469
Query 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
F + P S Y + + + S+GS S +++P PP+N+ + N
Sbjct 470 DGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVK-AEITVNT 528
Query 232 RWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290
L V+W+ P N+ +++R+ L + + KT + K ++ D + +VV
Sbjct 529 GLLKVSWEKPVFPENNLQFQIRYGLSGKEIQWKTHEVFDAKSKSASLLVSDLCA--VYVV 586
Query 291 QLRAQEEFGQGEWSEWSPEA 310
Q+R + G G WS WS A
Sbjct 587 QVRCRRLDGLGYWSNWSSPA 606
Score = 33.1 bits (74), Expect = 7.2, Method: Compositional matrix adjust.
Identities = 34/159 (21%), Positives = 67/159 (42%), Gaps = 8/159 (5%)
Query 157 PAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCVASSVGSKF-SKTQTFQGCGILQ 215
P +D + Q + + C + VP ++ ++ +S G F S + Q +++
Sbjct 155 PLKDSFQTVQCNCSLRGCECHVPVPRAKLNYALLMYLEITSAGVSFQSPLMSLQPMLVVK 214
Query 216 PDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQH 275
PDPP + + L ++W S + + L+++++Y E S
Sbjct 215 PDPPLGLHMEVTDDGN--LKISWD---SQTMAPFPLQYQVKY-LENSTIVREAAEIVSAT 268
Query 276 HCVIHDAWSGLRHVVQLRAQEEFGQGEWSEW-SPEAMGT 313
++ G + VQ+R++ G G WS+W SP+ T
Sbjct 269 SLLVDSVLPGSSYEVQVRSKRLDGSGVWSDWSSPQVFTT 307
>8dh8_B B Leptin receptor
Length=863
Score = 42.0 bits (97), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 10/200 (5%)
Query 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAED------FQEPCQYSQES 171
+SC L+ + C W P + SL V L ++ D EP +
Sbjct 410 NISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDSPSIHPTSEPKNCVLQR 469
Query 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
F + P S Y + + + S+GS S +++P PP+N+ + N
Sbjct 470 DGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVK-AEITVNT 528
Query 232 RWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290
L V+W+ P N+ +++R+ L + + KT + K ++ D + +VV
Sbjct 529 GLLKVSWEKPVFPENNLQFQIRYGLSGKEIQWKTHEVFDAKSKSASLLVSDLCA--VYVV 586
Query 291 QLRAQEEFGQGEWSEWSPEA 310
Q+R + G G WS WS A
Sbjct 587 QVRCRRLDGLGYWSNWSSPA 606
Score = 33.1 bits (74), Expect = 7.2, Method: Compositional matrix adjust.
Identities = 34/159 (21%), Positives = 67/159 (42%), Gaps = 8/159 (5%)
Query 157 PAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMCVASSVGSKF-SKTQTFQGCGILQ 215
P +D + Q + + C + VP ++ ++ +S G F S + Q +++
Sbjct 155 PLKDSFQTVQCNCSLRGCECHVPVPRAKLNYALLMYLEITSAGVSFQSPLMSLQPMLVVK 214
Query 216 PDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQH 275
PDPP + + L ++W S + + L+++++Y E S
Sbjct 215 PDPPLGLHMEVTDDGN--LKISWD---SQTMAPFPLQYQVKY-LENSTIVREAAEIVSAT 268
Query 276 HCVIHDAWSGLRHVVQLRAQEEFGQGEWSEW-SPEAMGT 313
++ G + VQ+R++ G G WS+W SP+ T
Sbjct 269 SLLVDSVLPGSSYEVQVRSKRLDGSGVWSDWSSPQVFTT 307
>3ew3_C C Prolactin receptor
Length=221
Score = 40.8 bits (94), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 47/204 (23%), Positives = 77/204 (38%), Gaps = 16/204 (8%)
Query 114 PEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQK 173
P +P++ R C W P L T L K E C + S
Sbjct 5 PGKPEIHKCRSPDKETFTCWWNPGXXXXLPTNYSLTYSK----EGEKTTYECPDYKTSGP 60
Query 174 FSCQLAVPEGDS-SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANIT--VTAVARN 230
SC + YI+++ + +GS S I++P+PP N+T V
Sbjct 61 NSCFFSKQYTSIWKIYIITVNATNQMGSSSSDPLYVDVTYIVEPEPPRNLTLEVKXXXXX 120
Query 231 PRWLSVTWQDP--HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHC--VIHDAWSGL 286
+L V W P + +E+R + E ++ W + H + D + G
Sbjct 121 KTYLWVKWSPPTIXXXXXXXXTMEYEIRLKPEEAE---EWEIHFTGHQTQFKVFDLYPGQ 177
Query 287 RHVVQLRAQEEFGQGEWSEWSPEA 310
+++VQ R + + G WS WS E+
Sbjct 178 KYLVQTRCKPD--HGYWSRWSQES 199
>1bp3_B B PROTEIN (PROLACTIN RECEPTOR)
Length=211
Score = 40.4 bits (93), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 45/202 (22%), Positives = 73/202 (36%), Gaps = 12/202 (6%)
Query 112 VPPEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQES 171
+PP +P++ R C W P + T L + E C
Sbjct 2 LPPGKPEIFKCRSPNKETFTCWWRPGTDGXXXTNYSLTYHR----EGETLMHECPDYITG 57
Query 172 QKFSCQLAVPEGDS-SFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARN 230
SC YI+ + + S FS I+QPDPP + V
Sbjct 58 GPNSCHFGKQYTSMWRTYIMMVNATNXXXSSFSDELYVDVTYIVQPDPPLELAVEVKQPE 117
Query 231 PR--WLSVTWQDPH--SWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL 286
R +L + W P + ++ L +E+R + E++ + Q I G
Sbjct 118 DRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEI-HFAGQQTEFKILSLHPGQ 176
Query 287 RHVVQLRAQEEFGQGEWSEWSP 308
+++VQ+R + + G WS WSP
Sbjct 177 KYLVQVRCKPD--HGYWSAWSP 196
>7z3r_B B Leptin receptor
Length=330
Score = 40.8 bits (94), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 81/200 (41%), Gaps = 10/200 (5%)
Query 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAED------FQEPCQYSQES 171
+SC L+ + C W P + SL V L ++ D EP +
Sbjct 128 NISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDSPSIHPTSEPKNCVLQR 187
Query 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
F + P S Y + + + S+GS S +++P PP+N+ + N
Sbjct 188 DGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVK-AEITVNT 246
Query 232 RWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290
L V+W+ P N+ +++R+ L + + KT + K ++ D +VV
Sbjct 247 GLLKVSWEKPVFPENNLQFQIRYGLSGKEIQWKTHEVFDAKSKSASLLVSDL--SAVYVV 304
Query 291 QLRAQEEFGQGEWSEWSPEA 310
Q+R + G G WS WS A
Sbjct 305 QVRCRRLDGLGYWSNWSSPA 324
>8avd_F F Leptin receptor
Length=868
Score = 41.6 bits (96), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 10/200 (5%)
Query 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAED------FQEPCQYSQES 171
+SC L+ + C W P + SL V L ++ D EP +
Sbjct 410 NISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDSPSIHPTSEPKNCVLQR 469
Query 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
F + P S Y + + + S+GS S +++P PP+N+ + N
Sbjct 470 DGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVK-AEITVNT 528
Query 232 RWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290
L V+W+ P N+ +++R+ L + + KT + K ++ D + +VV
Sbjct 529 GLLKVSWEKPVFPENNLQFQIRYGLSGKEIQWKTHEVFDAKSKSASLLVSDLCA--VYVV 586
Query 291 QLRAQEEFGQGEWSEWSPEA 310
Q+R + G G WS WS A
Sbjct 587 QVRCRRLDGLGYWSNWSSPA 606
>8avd_D D Leptin receptor
Length=868
Score = 41.6 bits (96), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 10/200 (5%)
Query 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAED------FQEPCQYSQES 171
+SC L+ + C W P + SL V L ++ D EP +
Sbjct 410 NISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDSPSIHPTSEPKNCVLQR 469
Query 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
F + P S Y + + + S+GS S +++P PP+N+ + N
Sbjct 470 DGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVK-AEITVNT 528
Query 232 RWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290
L V+W+ P N+ +++R+ L + + KT + K ++ D + +VV
Sbjct 529 GLLKVSWEKPVFPENNLQFQIRYGLSGKEIQWKTHEVFDAKSKSASLLVSDLCA--VYVV 586
Query 291 QLRAQEEFGQGEWSEWSPEA 310
Q+R + G G WS WS A
Sbjct 587 QVRCRRLDGLGYWSNWSSPA 606
>8avd_B B Leptin receptor
Length=868
Score = 41.6 bits (96), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 10/200 (5%)
Query 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAED------FQEPCQYSQES 171
+SC L+ + C W P + SL V L ++ D EP +
Sbjct 410 NISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDSPSIHPTSEPKNCVLQR 469
Query 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
F + P S Y + + + S+GS S +++P PP+N+ + N
Sbjct 470 DGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVK-AEITVNT 528
Query 232 RWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290
L V+W+ P N+ +++R+ L + + KT + K ++ D + +VV
Sbjct 529 GLLKVSWEKPVFPENNLQFQIRYGLSGKEIQWKTHEVFDAKSKSASLLVSDLCA--VYVV 586
Query 291 QLRAQEEFGQGEWSEWSPEA 310
Q+R + G G WS WS A
Sbjct 587 QVRCRRLDGLGYWSNWSSPA 606
>8avb_B B Leptin receptor
Length=835
Score = 41.6 bits (96), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 10/200 (5%)
Query 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAED------FQEPCQYSQES 171
+SC L+ + C W P + SL V L ++ D EP +
Sbjct 427 NISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDSPSIHPTSEPKNCVLQR 486
Query 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
F + P S Y + + + S+GS S +++P PP+N+ + N
Sbjct 487 DGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVK-AEITVNT 545
Query 232 RWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290
L V+W+ P N+ +++R+ L + + KT + K ++ D + +VV
Sbjct 546 GLLKVSWEKPVFPENNLQFQIRYGLSGKEIQWKTHEVFDAKSKSASLLVSDLCA--VYVV 603
Query 291 QLRAQEEFGQGEWSEWSPEA 310
Q+R + G G WS WS A
Sbjct 604 QVRCRRLDGLGYWSNWSSPA 623
>8avb_C F Leptin receptor
Length=835
Score = 41.6 bits (96), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 10/200 (5%)
Query 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAED------FQEPCQYSQES 171
+SC L+ + C W P + SL V L ++ D EP +
Sbjct 427 NISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDSPSIHPTSEPKNCVLQR 486
Query 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
F + P S Y + + + S+GS S +++P PP+N+ + N
Sbjct 487 DGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVK-AEITVNT 545
Query 232 RWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290
L V+W+ P N+ +++R+ L + + KT + K ++ D + +VV
Sbjct 546 GLLKVSWEKPVFPENNLQFQIRYGLSGKEIQWKTHEVFDAKSKSASLLVSDLCA--VYVV 603
Query 291 QLRAQEEFGQGEWSEWSPEA 310
Q+R + G G WS WS A
Sbjct 604 QVRCRRLDGLGYWSNWSSPA 623
>8avc_F F Leptin receptor
Length=868
Score = 41.6 bits (96), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 10/200 (5%)
Query 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAED------FQEPCQYSQES 171
+SC L+ + C W P + SL V L ++ D EP +
Sbjct 410 NISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDSPSIHPTSEPKNCVLQR 469
Query 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
F + P S Y + + + S+GS S +++P PP+N+ + N
Sbjct 470 DGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVK-AEITVNT 528
Query 232 RWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290
L V+W+ P N+ +++R+ L + + KT + K ++ D + +VV
Sbjct 529 GLLKVSWEKPVFPENNLQFQIRYGLSGKEIQWKTHEVFDAKSKSASLLVSDLCA--VYVV 586
Query 291 QLRAQEEFGQGEWSEWSPEA 310
Q+R + G G WS WS A
Sbjct 587 QVRCRRLDGLGYWSNWSSPA 606
>8avc_D D Leptin receptor
Length=868
Score = 41.6 bits (96), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 10/200 (5%)
Query 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAED------FQEPCQYSQES 171
+SC L+ + C W P + SL V L ++ D EP +
Sbjct 410 NISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDSPSIHPTSEPKNCVLQR 469
Query 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
F + P S Y + + + S+GS S +++P PP+N+ + N
Sbjct 470 DGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVK-AEITVNT 528
Query 232 RWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290
L V+W+ P N+ +++R+ L + + KT + K ++ D + +VV
Sbjct 529 GLLKVSWEKPVFPENNLQFQIRYGLSGKEIQWKTHEVFDAKSKSASLLVSDLCA--VYVV 586
Query 291 QLRAQEEFGQGEWSEWSPEA 310
Q+R + G G WS WS A
Sbjct 587 QVRCRRLDGLGYWSNWSSPA 606
>8avc_B B Leptin receptor
Length=868
Score = 41.6 bits (96), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 10/200 (5%)
Query 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAED------FQEPCQYSQES 171
+SC L+ + C W P + SL V L ++ D EP +
Sbjct 410 NISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDSPSIHPTSEPKNCVLQR 469
Query 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
F + P S Y + + + S+GS S +++P PP+N+ + N
Sbjct 470 DGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVK-AEITVNT 528
Query 232 RWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290
L V+W+ P N+ +++R+ L + + KT + K ++ D + +VV
Sbjct 529 GLLKVSWEKPVFPENNLQFQIRYGLSGKEIQWKTHEVFDAKSKSASLLVSDLCA--VYVV 586
Query 291 QLRAQEEFGQGEWSEWSPEA 310
Q+R + G G WS WS A
Sbjct 587 QVRCRRLDGLGYWSNWSSPA 606
>8dh9_B B Leptin receptor
Length=557
Score = 40.8 bits (94), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 10/200 (5%)
Query 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAED------FQEPCQYSQES 171
+SC L+ + C W P + SL V L ++ D EP +
Sbjct 104 NISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDSPSIHPTSEPKNCVLQR 163
Query 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
F + P S Y + + + S+GS S +++P PP+N+ + N
Sbjct 164 DGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVK-AEITVNT 222
Query 232 RWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290
L V+W+ P N+ +++R+ L + + KT + K ++ D + +VV
Sbjct 223 GLLKVSWEKPVFPENNLQFQIRYGLSGKEIQWKTHEVFDAKSKSASLLVSDLCA--VYVV 280
Query 291 QLRAQEEFGQGEWSEWSPEA 310
Q+R + G G WS WS A
Sbjct 281 QVRCRRLDGLGYWSNWSSPA 300
>8dh9_A A Leptin receptor
Length=557
Score = 40.8 bits (94), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 10/200 (5%)
Query 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAED------FQEPCQYSQES 171
+SC L+ + C W P + SL V L ++ D EP +
Sbjct 104 NISCETDGYLTKMTCRWSPSTIQSLVGSTVQLRYHRRSLYCPDSPSIHPTSEPKNCVLQR 163
Query 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
F + P S Y + + + S+GS S +++P PP+N+ + N
Sbjct 164 DGFYECVFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSNVK-AEITVNT 222
Query 232 RWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290
L V+W+ P N+ +++R+ L + + KT + K ++ D + +VV
Sbjct 223 GLLKVSWEKPVFPENNLQFQIRYGLSGKEIQWKTHEVFDAKSKSASLLVSDLCA--VYVV 280
Query 291 QLRAQEEFGQGEWSEWSPEA 310
Q+R + G G WS WS A
Sbjct 281 QVRCRRLDGLGYWSNWSSPA 300
>2lfg_A A Prolactin receptor
Length=113
Score = 37.0 bits (84), Expect = 0.091, Method: Composition-based stats.
Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 7/100 (7%)
Query 213 ILQPDPPANITVTAVARNPR--WLSVTWQDPH--SWNSSFYRLRFELRYRAERSKTFTTW 268
I+QPDPP + V R +L + W P + ++ L +E+R + E++ +
Sbjct 3 IVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWEIH 62
Query 269 MVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWSEWSP 308
Q I G +++VQ+R + + G WS WSP
Sbjct 63 FAGQ-QTEFKILSLHPGQKYLVQVRCKPD--HGYWSAWSP 99
>6smc_D D Interleukin-12 subunit beta
Length=344
Score = 38.5 bits (88), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 53/246 (22%), Positives = 92/246 (37%), Gaps = 42/246 (17%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG++V LTC E ED+ T R GS G+ L + + D+G Y+C++
Sbjct 42 PGETVNLTCDTPE-EDDITWTSDQRHGVIGS--------GKTLTITVKEFLDAGQYTCHK 92
Query 99 AGRPAGTVHLLVDVP-------------PEEPQLSCFRKSPLSNVVCEWGPRSTPSLT-- 143
HLL+ + L C + C W + L
Sbjct 93 XXETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFN 152
Query 144 ---------TKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQ--LAVPEGDSSFYIVSM 192
++AV ++ Q E SCQ + P + + I
Sbjct 153 IKSSSSSPDSRAVTCGMASLSAEKVTLD---QRDYEKYSVSCQEDVTCPTAEETLPIELA 209
Query 193 CVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS--SFYR 250
A + + +F I++PDPP N+ + + + + V+W+ P SW++ S++
Sbjct 210 LEARQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLKNSQ--VEVSWEYPDSWSTPHSYFS 267
Query 251 LRFELR 256
L+F +R
Sbjct 268 LKFFVR 273
>8il3_A A Light chain
Length=218
Score = 37.4 bits (85), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 23/83 (28%), Positives = 36/83 (43%), Gaps = 20/83 (24%)
Query 39 PGDSVTLTCPGVEPEDNATV---HWVLRKPA-------------AGSHPSRWAGMGRR-- 80
PG T+TC E DN + HW +KP P+R++G G R
Sbjct 15 PGQRATITCRASESVDNFGITFMHWYQQKPGQPPKLLIYRASNLESGVPARFSGSGSRTD 74
Query 81 --LLLRSVQLHDSGNYSCYRAGR 101
L + V+ +D+ NY C ++ +
Sbjct 75 FTLTINPVEANDTANYYCQQSSK 97
>2djs_A A Ephrin type-B receptor 1
Length=108
Score = 35.4 bits (80), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 21/78 (27%), Positives = 38/78 (49%), Gaps = 2/78 (3%)
Query 227 VARNPRWLSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL 286
V+ R ++++W P N L +E+RY + F + M + + I G+
Sbjct 17 VSATMRSITLSWPQPEQPNGII--LDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRPGM 74
Query 287 RHVVQLRAQEEFGQGEWS 304
+VVQ+RA+ G G++S
Sbjct 75 VYVVQVRARTVAGYGKFS 92
>8ivw_F F Light chain of antibody 10V8 Fab fragment
Length=215
Score = 36.2 bits (82), Expect = 0.40, Method: Compositional matrix adjust.
Identities = 34/129 (26%), Positives = 52/129 (40%), Gaps = 35/129 (27%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRWAGMGR-- 79
L++ GD VT+TC ++ +HW +KP A PSR++G G
Sbjct 11 LSASVGDRVTITCTASSSVSSSYLHWYQQKPGKAPKLLIYRTSNLASGVPSRFSGSGSGT 70
Query 80 --RLLLRSVQLHDSGNYSCYRAGRP----AGTVHLLVD----------VPPEEPQLSCFR 123
L + S+Q D Y C++ R G + + PP + QL
Sbjct 71 DFTLTISSLQPEDFATYYCHQYYRSPPTFGGGTKVEIKRTVAAPSVFIFPPSDEQL---- 126
Query 124 KSPLSNVVC 132
KS ++VVC
Sbjct 127 KSGTASVVC 135
>8ivw_C C Light chain of antibody 10V8 Fab fragment
Length=215
Score = 36.2 bits (82), Expect = 0.40, Method: Compositional matrix adjust.
Identities = 34/129 (26%), Positives = 52/129 (40%), Gaps = 35/129 (27%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRWAGMGR-- 79
L++ GD VT+TC ++ +HW +KP A PSR++G G
Sbjct 11 LSASVGDRVTITCTASSSVSSSYLHWYQQKPGKAPKLLIYRTSNLASGVPSRFSGSGSGT 70
Query 80 --RLLLRSVQLHDSGNYSCYRAGRP----AGTVHLLVD----------VPPEEPQLSCFR 123
L + S+Q D Y C++ R G + + PP + QL
Sbjct 71 DFTLTISSLQPEDFATYYCHQYYRSPPTFGGGTKVEIKRTVAAPSVFIFPPSDEQL---- 126
Query 124 KSPLSNVVC 132
KS ++VVC
Sbjct 127 KSGTASVVC 135
>8ivw_L L Light chain of antibody 10V8 Fab fragment
Length=215
Score = 36.2 bits (82), Expect = 0.40, Method: Compositional matrix adjust.
Identities = 34/129 (26%), Positives = 52/129 (40%), Gaps = 35/129 (27%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRWAGMGR-- 79
L++ GD VT+TC ++ +HW +KP A PSR++G G
Sbjct 11 LSASVGDRVTITCTASSSVSSSYLHWYQQKPGKAPKLLIYRTSNLASGVPSRFSGSGSGT 70
Query 80 --RLLLRSVQLHDSGNYSCYRAGRP----AGTVHLLVD----------VPPEEPQLSCFR 123
L + S+Q D Y C++ R G + + PP + QL
Sbjct 71 DFTLTISSLQPEDFATYYCHQYYRSPPTFGGGTKVEIKRTVAAPSVFIFPPSDEQL---- 126
Query 124 KSPLSNVVC 132
KS ++VVC
Sbjct 127 KSGTASVVC 135
>8ivw_I I Light chain of antibody 10V8 Fab fragment
Length=215
Score = 36.2 bits (82), Expect = 0.40, Method: Compositional matrix adjust.
Identities = 34/129 (26%), Positives = 52/129 (40%), Gaps = 35/129 (27%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRWAGMGR-- 79
L++ GD VT+TC ++ +HW +KP A PSR++G G
Sbjct 11 LSASVGDRVTITCTASSSVSSSYLHWYQQKPGKAPKLLIYRTSNLASGVPSRFSGSGSGT 70
Query 80 --RLLLRSVQLHDSGNYSCYRAGRP----AGTVHLLVD----------VPPEEPQLSCFR 123
L + S+Q D Y C++ R G + + PP + QL
Sbjct 71 DFTLTISSLQPEDFATYYCHQYYRSPPTFGGGTKVEIKRTVAAPSVFIFPPSDEQL---- 126
Query 124 KSPLSNVVC 132
KS ++VVC
Sbjct 127 KSGTASVVC 135
>6ani_D L Coltuximab Fab light chain
Length=211
Score = 36.2 bits (82), Expect = 0.45, Method: Compositional matrix adjust.
Identities = 32/130 (25%), Positives = 53/130 (41%), Gaps = 39/130 (30%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW------------------- 74
++++ PG+ VT+TC + +HW +KP G+ P RW
Sbjct 10 IMSASPGERVTMTCSASSGVN--YMHWYQQKP--GTSPRRWIYDTSKLASGVPARFSGSG 65
Query 75 AGMGRRLLLRSVQLHDSGNYSCYRAGRP--AGTVHLLVD----------VPPEEPQLSCF 122
+G L + S++ D+ Y C++ G G L + PP + QL
Sbjct 66 SGTDYSLTISSMEPEDAATYYCHQRGSYTFGGGTKLEIKRTVAAPSVFIFPPSDEQL--- 122
Query 123 RKSPLSNVVC 132
KS ++VVC
Sbjct 123 -KSGTASVVC 131
>6ani_F M Coltuximab Fab light chain
Length=211
Score = 36.2 bits (82), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 32/130 (25%), Positives = 53/130 (41%), Gaps = 39/130 (30%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW------------------- 74
++++ PG+ VT+TC + +HW +KP G+ P RW
Sbjct 10 IMSASPGERVTMTCSASSGVNY--MHWYQQKP--GTSPRRWIYDTSKLASGVPARFSGSG 65
Query 75 AGMGRRLLLRSVQLHDSGNYSCYRAGRP--AGTVHLLVD----------VPPEEPQLSCF 122
+G L + S++ D+ Y C++ G G L + PP + QL
Sbjct 66 SGTDYSLTISSMEPEDAATYYCHQRGSYTFGGGTKLEIKRTVAAPSVFIFPPSDEQL--- 122
Query 123 RKSPLSNVVC 132
KS ++VVC
Sbjct 123 -KSGTASVVC 131
>5uix_B L DH576 Fab light chain
Length=214
Score = 36.2 bits (82), Expect = 0.51, Method: Compositional matrix adjust.
Identities = 25/83 (30%), Positives = 37/83 (45%), Gaps = 18/83 (22%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAG-------------SHPSRWAGMGR-- 79
L++ GD VT+TC + DN ++W +KP PSR++G G
Sbjct 11 LSASVGDRVTITCQASQDIDNY-LNWYQQKPGKAPKLLIYDASNLETGVPSRFSGSGSGT 69
Query 80 --RLLLRSVQLHDSGNYSCYRAG 100
L + S+Q D G Y C + G
Sbjct 70 SFTLTISSLQPEDIGTYYCQKYG 92
>4hs8_C L antibody hu5B3.v2 Fab light chain
Length=218
Score = 35.8 bits (81), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 26/85 (31%), Positives = 41/85 (48%), Gaps = 20/85 (24%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATV---HWVLRKP---------AAGSH----PSRWAGMG 78
L++ GD VT+TC E DN + +W +KP +A +H PSR++G G
Sbjct 11 LSASVGDRVTITCRASESVDNYGISFMNWFQQKPGKAPKLLIYSASNHASGVPSRFSGSG 70
Query 79 R----RLLLRSVQLHDSGNYSCYRA 99
L + S+Q D Y C+++
Sbjct 71 SGTDFTLTISSLQPEDFATYYCHQS 95
>2q76_C C Fab F10.6.6 fragment Light Chain
Length=212
Score = 35.8 bits (81), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 30/110 (27%), Positives = 45/110 (41%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYTSQSMSGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++G G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGVYFCQQSGSWPRTFGGGTKLDIKRADAAPTVSIF 118
>2q76_A A Fab F10.6.6 fragment Light Chain
Length=212
Score = 35.8 bits (81), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 30/110 (27%), Positives = 45/110 (41%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYTSQSMSGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++G G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGVYFCQQSGSWPRTFGGGTKLDIKRADAAPTVSIF 118
>1p2c_A A light chain anti-lysozyme antibody F10.6.6
Length=212
Score = 35.8 bits (81), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 30/110 (27%), Positives = 45/110 (41%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYTSQSMSGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++G G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGVYFCQQSGSWPRTFGGGTKLDIKRADAAPTVSIF 118
>8cr6_A A Interleukin-12 subunit beta
Length=335
Score = 36.2 bits (82), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 54/243 (22%), Positives = 87/243 (36%), Gaps = 36/243 (15%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYR 98
PG++V LTC E ED+ T R GS G+ L + + D+G Y+C+
Sbjct 42 PGETVNLTCDTPE-EDDITWTSDQRHGVIGS--------GKTLTITVKEFLDAGQYTCHX 92
Query 99 AGRPAGTVHLLVDVP-------------PEEPQLSCFRKSPLSNVVCEWGPRSTPSLTTK 145
HLL+ + L C + C W + L
Sbjct 93 XXXTLSHSHLLLHKKENGIWSTEILKNFKNKTFLKCEAPNYSGRFTCSWLVQRNMDLKFN 152
Query 146 AVLLV-----RKFQNSPAEDFQEPCQYSQ---ESQKFSCQ--LAVPEGDSSFYIVSMCVA 195
R A E Q E SCQ + P + + I A
Sbjct 153 IKSSSSSPDSRAVTCGMASLSAEKVTLDQRDYEKYSVSCQEDVTCPTAEETLPIELALEA 212
Query 196 SSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQDPHSWNS--SFYRLRF 253
+ + +F I++PDPP N+ + + + V+W+ P SW++ S++ L+F
Sbjct 213 RQQNKYENYSTSFFIRDIIKPDPPKNLQMKPLKXXQ--VEVSWEYPDSWSTPHSYFSLKF 270
Query 254 ELR 256
+R
Sbjct 271 FVR 273
>1p2c_D D light chain anti-lysozyme antibody F10.6.6
Length=212
Score = 35.8 bits (81), Expect = 0.62, Method: Compositional matrix adjust.
Identities = 30/110 (27%), Positives = 45/110 (41%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYTSQSMSGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++G G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGVYFCQQSGSWPRTFGGGTKLDIKRADAAPTVSIF 118
>6pis_F M ANTIBODY FAB FRAGMENT LIGHT CHAIN
Length=213
Score = 35.4 bits (80), Expect = 0.74, Method: Compositional matrix adjust.
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 18/85 (21%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAG-------------SHPSRWAGMGR-- 79
L+ PGD VT+TC + N +HW +KP PSR++G G
Sbjct 11 LSVSPGDKVTITCKASQ-NINQYLHWYQQKPEEAPKLLIYGASNLQTGIPSRFSGSGYGT 69
Query 80 --RLLLRSVQLHDSGNYSCYRAGRP 102
L + S+ D G Y C + P
Sbjct 70 DFSLTINSLDSEDVGTYFCQQGYTP 94
>6pis_C L ANTIBODY FAB FRAGMENT LIGHT CHAIN
Length=213
Score = 35.4 bits (80), Expect = 0.74, Method: Compositional matrix adjust.
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 18/85 (21%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAG-------------SHPSRWAGMGR-- 79
L+ PGD VT+TC + N +HW +KP PSR++G G
Sbjct 11 LSVSPGDKVTITCKASQ-NINQYLHWYQQKPEEAPKLLIYGASNLQTGIPSRFSGSGYGT 69
Query 80 --RLLLRSVQLHDSGNYSCYRAGRP 102
L + S+ D G Y C + P
Sbjct 70 DFSLTINSLDSEDVGTYFCQQGYTP 94
>1x5l_A A Ephrin type-A receptor 8
Length=111
Score = 33.9 bits (76), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 22/82 (27%), Positives = 39/82 (48%), Gaps = 4/82 (5%)
Query 234 LSVTWQDPHSWNSSFYRLRFELRYRAERSKTFTTW-MVKDLQHHCVIHDAWSGLRHVVQL 292
+S+ WQ+P N L +E++Y E+ K ++ +K + + G R+V Q+
Sbjct 27 VSLLWQEPEQPNGII--LEYEIKY-YEKDKEMQSYSTLKAVTTRATVSGLKPGTRYVFQV 83
Query 293 RAQEEFGQGEWSEWSPEAMGTP 314
RA+ G G +S+ G P
Sbjct 84 RARTSAGCGRFSQAMEVETGKP 105
>5oj6_B B MAM domain-containing glycosylphosphatidylinositol anchor
protein 1
Length=910
Score = 35.8 bits (81), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 55/213 (26%), Positives = 79/213 (37%), Gaps = 56/213 (26%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCY- 97
PGD+VT+ C + V W + G P G L + +++ DSG Y+C
Sbjct 236 PGDNVTMQCSLTGGDPQPEVLW---SHSPGPLPPNSLVQGGNLTIWRIRVEDSGYYNCTA 292
Query 98 --RAGRPA-GTVHLLV------------DVPPE--------EPQLSCFRKS-PLSNVVCE 133
G PA TV+LLV DV E + +LSC + P VV
Sbjct 293 INNVGNPAKKTVNLLVRSMKNATFQITPDVIKESETIQLGQDLKLSCHVDAVPQEKVVYS 352
Query 134 WGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMC 193
W P + +L+ R N P E +C L + + S Y +C
Sbjct 353 WYKNGKPXXXSDRLLITR---NDP------------ELPPVTCSLEIIDLRFSDYGTYLC 397
Query 194 VASSVGSKFSKTQTFQGCGILQPDPPANITVTA 226
VA TFQG I PD + +++
Sbjct 398 VA-----------TFQGAPI--PDLSVEVNISS 417
>8cby_A L anti-cortisol (17) Fab (light chain)
Length=211
Score = 34.7 bits (78), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 22/85 (26%), Positives = 39/85 (46%), Gaps = 23/85 (27%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
V+++ PG+ VT+TC + +HW +KP G+ P RW +G+ R
Sbjct 9 AVMSAFPGEEVTMTCSASSSIN--YMHWYQQKP--GTSPKRWIYDTSKLASGVPARFSGS 64
Query 81 -------LLLRSVQLHDSGNYSCYR 98
L + S++ D+ Y C++
Sbjct 65 GSGTSYSLTISSMEAEDAATYYCHQ 89
>8cbz_A L anti-cortisol (17) Fab (light chain)
Length=211
Score = 34.7 bits (78), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 22/85 (26%), Positives = 39/85 (46%), Gaps = 23/85 (27%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
V+++ PG+ VT+TC + +HW +KP G+ P RW +G+ R
Sbjct 9 AVMSAFPGEEVTMTCSASSSIN--YMHWYQQKP--GTSPKRWIYDTSKLASGVPARFSGS 64
Query 81 -------LLLRSVQLHDSGNYSCYR 98
L + S++ D+ Y C++
Sbjct 65 GSGTSYSLTISSMEAEDAATYYCHQ 89
>8cbx_A L anti-cortisol (17) Fab (light chain)
Length=211
Score = 34.7 bits (78), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 22/85 (26%), Positives = 39/85 (46%), Gaps = 23/85 (27%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
V+++ PG+ VT+TC + +HW +KP G+ P RW +G+ R
Sbjct 9 AVMSAFPGEEVTMTCSASSSIN--YMHWYQQKP--GTSPKRWIYDTSKLASGVPARFSGS 64
Query 81 -------LLLRSVQLHDSGNYSCYR 98
L + S++ D+ Y C++
Sbjct 65 GSGTSYSLTISSMEAEDAATYYCHQ 89
>8cc1_A L anti-cortisol (17) Fab (light chain)
Length=211
Score = 34.7 bits (78), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 22/85 (26%), Positives = 39/85 (46%), Gaps = 23/85 (27%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
V+++ PG+ VT+TC + +HW +KP G+ P RW +G+ R
Sbjct 9 AVMSAFPGEEVTMTCSASSSIN--YMHWYQQKP--GTSPKRWIYDTSKLASGVPARFSGS 64
Query 81 -------LLLRSVQLHDSGNYSCYR 98
L + S++ D+ Y C++
Sbjct 65 GSGTSYSLTISSMEAEDAATYYCHQ 89
>8cc0_A L anti-cortisol (17) Fab (light chain)
Length=211
Score = 34.7 bits (78), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 22/85 (26%), Positives = 39/85 (46%), Gaps = 23/85 (27%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
V+++ PG+ VT+TC + +HW +KP G+ P RW +G+ R
Sbjct 9 AVMSAFPGEEVTMTCSASSSIN--YMHWYQQKP--GTSPKRWIYDTSKLASGVPARFSGS 64
Query 81 -------LLLRSVQLHDSGNYSCYR 98
L + S++ D+ Y C++
Sbjct 65 GSGTSYSLTISSMEAEDAATYYCHQ 89
>6d9w_C L Fab Light Chain
Length=213
Score = 34.7 bits (78), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 45/110 (41%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K ++ PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYVSQSSSGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGMYFCQQSNSWPRTFGGGTKLEIKRADAAPTVSIF 118
>5kte_C L Fab Light Chain
Length=213
Score = 34.7 bits (78), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 45/110 (41%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K ++ PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYVSQSSSGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGMYFCQQSNSWPRTFGGGTKLEIKRADAAPTVSIF 118
>8hpk_C L Fab fragment Light chain
Length=215
Score = 34.7 bits (78), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 24/110 (22%), Positives = 45/110 (41%), Gaps = 21/110 (19%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRWAGMGR- 79
++++ G+ VT+TC ++ +HW ++P A P R++G G
Sbjct 10 IMSASLGERVTMTCTASSSVTSSYLHWYQQRPGSSPKLWIYSTSNLASGVPGRFSGRGSG 69
Query 80 ---RLLLRSVQLHDSGNYSCYRAGRP----AGTVHLLVDVPPEEPQLSCF 122
L + S++ D+ Y C++ R G L + P +S F
Sbjct 70 TSYSLTISSMEAEDAATYYCHQYHRSPPTFGGGTKLEIKRADAAPTVSIF 119
>1mlb_A A IGG1-KAPPA D44.1 FAB (LIGHT CHAIN)
Length=214
Score = 34.7 bits (78), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 45/110 (41%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K ++ PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYVSQSSSGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGMYFCQQSNSWPRTFGGGTKLEIKRADAAPTVSIF 118
>1mlc_C C IGG1-KAPPA D44.1 FAB (LIGHT CHAIN)
Length=214
Score = 34.7 bits (78), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 45/110 (41%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K ++ PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYVSQSSSGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGMYFCQQSNSWPRTFGGGTKLEIKRADAAPTVSIF 118
>1mlc_A A IGG1-KAPPA D44.1 FAB (LIGHT CHAIN)
Length=214
Score = 34.7 bits (78), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 45/110 (41%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K ++ PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYVSQSSSGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGMYFCQQSNSWPRTFGGGTKLEIKRADAAPTVSIF 118
>5u8q_D L Fv 24-60 light chain
Length=108
Score = 33.1 bits (74), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 24/83 (29%), Positives = 37/83 (45%), Gaps = 18/83 (22%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 11 TLSVTPGDSVSLSCRASQTISN-NLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 69
Query 80 ---RLLLRSVQLHDSGNYSCYRA 99
L + SV+ D G Y C ++
Sbjct 70 TDFTLSINSVETEDFGMYFCQQS 92
>7ut3_B L G10C Light chain
Length=212
Score = 34.7 bits (78), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 27/109 (25%), Positives = 45/109 (41%), Gaps = 22/109 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRWAGMGRR 80
++++ PG+ VTLTC +HW +KP A P+R++G G
Sbjct 10 IMSASPGEKVTLTCSA--SSGIGFIHWYQQKPGTSPKRWIYDTSILASGVPARFSGSGSE 67
Query 81 ----LLLRSVQLHDSGNYSCY-RAGRP--AGTVHLLVDVPPEEPQLSCF 122
L + ++ D+ Y C+ R+ P G L + P +S F
Sbjct 68 TSYSLTITIMEAEDAATYYCHQRSSYPTFGGGTKLEIKRADAAPTVSIF 116
>5u8r_C L Fv 24-60 light chain
Length=108
Score = 33.1 bits (74), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 24/83 (29%), Positives = 37/83 (45%), Gaps = 18/83 (22%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 11 TLSVTPGDSVSLSCRASQTISN-NLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 69
Query 80 ---RLLLRSVQLHDSGNYSCYRA 99
L + SV+ D G Y C ++
Sbjct 70 TDFTLSINSVETEDFGMYFCQQS 92
>8gy5_B B light chain
Length=214
Score = 34.3 bits (77), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 35/129 (27%), Positives = 52/129 (40%), Gaps = 36/129 (28%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAA-------------GSHPSRWAGMGR-- 79
L++ GDS+T+TC N ++W +KP G PSR++G G
Sbjct 11 LSASVGDSITITCRA-SLSINTFLNWYQQKPGKAPNLLIYAASSLHGGVPSRFSGSGSGT 69
Query 80 --RLLLRSVQLHDSGNYSCYRAGR------PAGTVHLLVDV--------PPEEPQLSCFR 123
L +R++Q D Y C ++ P V V PP + QL
Sbjct 70 DFTLTIRTLQPEDFATYYCQQSSNTPFTFGPGTVVDFRRTVAAPSVFIFPPSDEQL---- 125
Query 124 KSPLSNVVC 132
KS ++VVC
Sbjct 126 KSGTASVVC 134
>8gy5_E L light chain
Length=214
Score = 34.3 bits (77), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 35/129 (27%), Positives = 52/129 (40%), Gaps = 36/129 (28%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAA-------------GSHPSRWAGMGR-- 79
L++ GDS+T+TC N ++W +KP G PSR++G G
Sbjct 11 LSASVGDSITITCRA-SLSINTFLNWYQQKPGKAPNLLIYAASSLHGGVPSRFSGSGSGT 69
Query 80 --RLLLRSVQLHDSGNYSCYRAGR------PAGTVHLLVDV--------PPEEPQLSCFR 123
L +R++Q D Y C ++ P V V PP + QL
Sbjct 70 DFTLTIRTLQPEDFATYYCQQSSNTPFTFGPGTVVDFRRTVAAPSVFIFPPSDEQL---- 125
Query 124 KSPLSNVVC 132
KS ++VVC
Sbjct 126 KSGTASVVC 134
>5oj2_A A MAM domain-containing glycosylphosphatidylinositol anchor
protein 1
Length=970
Score = 35.0 bits (79), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 55/213 (26%), Positives = 80/213 (38%), Gaps = 56/213 (26%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCY- 97
PGD+VT+ C + V W + G P G L + +++ DSG Y+C
Sbjct 236 PGDNVTMQCSLTGGDPQPEVLW---SHSPGPLPPNSLVQGGNLTIWRIRVEDSGYYNCTA 292
Query 98 --RAGRPA-GTVHLLV------------DVPPE--------EPQLSCFRKS-PLSNVVCE 133
G PA TV+LLV DV E + +LSC + P VV
Sbjct 293 INNVGNPAKKTVNLLVRSMKNATFQITPDVIKESETIQLGQDLKLSCHVDAVPQEKVVYS 352
Query 134 WGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMC 193
W P+ + +L+ R N P E +C L + + S Y +C
Sbjct 353 WYKNGKPARFSDRLLITR---NDP------------ELPPVTCSLEIIDLRFSDYGTYLC 397
Query 194 VASSVGSKFSKTQTFQGCGILQPDPPANITVTA 226
VA TFQG I PD + +++
Sbjct 398 VA-----------TFQGAPI--PDLSVEVNISS 417
>6x7w_E C antibody vFP49.02 light chain
Length=214
Score = 34.3 bits (77), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 26/82 (32%), Positives = 37/82 (45%), Gaps = 20/82 (24%)
Query 33 GVLTSLPGDSVTLTCPGVEP-EDNATVHWVLRKP-------------AAGSHPSRWAGMG 78
L+ PGDSV+L+C + DN +HW L+K + PSR++G G
Sbjct 9 ATLSVTPGDSVSLSCRASQTISDN--LHWYLQKSHESPRLLIKYSSQSISGIPSRFSGSG 66
Query 79 R----RLLLRSVQLHDSGNYSC 96
L + SV+ D G Y C
Sbjct 67 SGTDFTLNINSVETEDFGMYFC 88
>6x7w_D L antibody vFP49.02 light chain
Length=214
Score = 34.3 bits (77), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 26/82 (32%), Positives = 37/82 (45%), Gaps = 20/82 (24%)
Query 33 GVLTSLPGDSVTLTCPGVEP-EDNATVHWVLRKP-------------AAGSHPSRWAGMG 78
L+ PGDSV+L+C + DN +HW L+K + PSR++G G
Sbjct 9 ATLSVTPGDSVSLSCRASQTISDN--LHWYLQKSHESPRLLIKYSSQSISGIPSRFSGSG 66
Query 79 R----RLLLRSVQLHDSGNYSC 96
L + SV+ D G Y C
Sbjct 67 SGTDFTLNINSVETEDFGMYFC 88
>7z3q_B B Leptin receptor
Length=232
Score = 34.3 bits (77), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 43/198 (22%), Positives = 80/198 (40%), Gaps = 12/198 (6%)
Query 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNS-------PAEDFQEPCQYSQE 170
+SC L+ + C W ST ++ L +R ++S EP +
Sbjct 30 NISCETDGYLTKMTCRWS-TSTXXXLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQ 88
Query 171 SQKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARN 230
S F + P S Y + + + S+GS S +++P PP+++ + N
Sbjct 89 SDGFYECIFQPIFLLSGYTMWIRIQHSLGSLDSPPTCVLPDSVVKPLPPSSVK-AEITIN 147
Query 231 PRWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHV 289
L ++W+ P N+ +++R+ L + + K + + K + D +
Sbjct 148 IGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDL--SAVYA 205
Query 290 VQLRAQEEFGQGEWSEWS 307
VQ+R + G G WS WS
Sbjct 206 VQVRCKRLDGLGYWSNWS 223
>7z3q_D D Leptin receptor
Length=232
Score = 34.3 bits (77), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 42/197 (21%), Positives = 76/197 (39%), Gaps = 10/197 (5%)
Query 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDF------QEPCQYSQES 171
+SC L+ + C W + SL + L + D EP +S
Sbjct 30 NISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQS 89
Query 172 QKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNP 231
F + P S Y + + + S+GS S +++P PP+++ + N
Sbjct 90 DGFYECIFQPIFLLSGYTMWIRIQHSLGSLDSPPTCVLPDSVVKPLPPSSVK-AEITINI 148
Query 232 RWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVV 290
L ++W+ P N+ +++R+ L + K + + K + D + V
Sbjct 149 GLLKISWEKPVFPENNLQFQIRYGLSGXXXQWKMYEVYDAKSKSVSLPVPDL--SAVYAV 206
Query 291 QLRAQEEFGQGEWSEWS 307
Q+R + G G WS WS
Sbjct 207 QVRCKRLDGLGYWSNWS 223
>1v7m_D M Monoclonal TN1 Fab Light Chain
Length=213
Score = 33.9 bits (76), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 27/111 (24%), Positives = 46/111 (41%), Gaps = 23/111 (21%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRWAGMGR 79
G++++ PG+ VT+TC + ++W +KP A P+R+ G G
Sbjct 9 GIMSASPGEKVTITCSA--SSSVSYMYWFQQKPGTSPKLWIYSTSNLASGVPARFRGSGS 66
Query 80 ----RLLLRSVQLHDSGNYSC-YRAGRP---AGTVHLLVDVPPEEPQLSCF 122
L + ++ D+ Y C R+G P G L + P +S F
Sbjct 67 GTSYSLTISRMEAEDAATYYCQQRSGYPRTFGGGTKLEIKRADAAPTVSIF 117
>1v7n_E N Monoclonal TN1 Fab Light Chain
Length=213
Score = 33.9 bits (76), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 27/111 (24%), Positives = 46/111 (41%), Gaps = 23/111 (21%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRWAGMGR 79
G++++ PG+ VT+TC + ++W +KP A P+R+ G G
Sbjct 9 GIMSASPGEKVTITCSA--SSSVSYMYWFQQKPGTSPKLWIYSTSNLASGVPARFRGSGS 66
Query 80 ----RLLLRSVQLHDSGNYSC-YRAGRP---AGTVHLLVDVPPEEPQLSCF 122
L + ++ D+ Y C R+G P G L + P +S F
Sbjct 67 GTSYSLTISRMEAEDAATYYCQQRSGYPRTFGGGTKLEIKRADAAPTVSIF 117
>1v7n_C M Monoclonal TN1 Fab Light Chain
Length=213
Score = 33.9 bits (76), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 27/111 (24%), Positives = 46/111 (41%), Gaps = 23/111 (21%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRWAGMGR 79
G++++ PG+ VT+TC + ++W +KP A P+R+ G G
Sbjct 9 GIMSASPGEKVTITCSA--SSSVSYMYWFQQKPGTSPKLWIYSTSNLASGVPARFRGSGS 66
Query 80 ----RLLLRSVQLHDSGNYSC-YRAGRP---AGTVHLLVDVPPEEPQLSCF 122
L + ++ D+ Y C R+G P G L + P +S F
Sbjct 67 GTSYSLTISRMEAEDAATYYCQQRSGYPRTFGGGTKLEIKRADAAPTVSIF 117
>1v7m_A L Monoclonal TN1 Fab Light Chain
Length=213
Score = 33.9 bits (76), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 27/111 (24%), Positives = 46/111 (41%), Gaps = 23/111 (21%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRWAGMGR 79
G++++ PG+ VT+TC + ++W +KP A P+R+ G G
Sbjct 9 GIMSASPGEKVTITCSA--SSSVSYMYWFQQKPGTSPKLWIYSTSNLASGVPARFRGSGS 66
Query 80 ----RLLLRSVQLHDSGNYSC-YRAGRP---AGTVHLLVDVPPEEPQLSCF 122
L + ++ D+ Y C R+G P G L + P +S F
Sbjct 67 GTSYSLTISRMEAEDAATYYCQQRSGYPRTFGGGTKLEIKRADAAPTVSIF 117
>5oj2_B B MAM domain-containing glycosylphosphatidylinositol anchor
protein 1
Length=970
Score = 34.7 bits (78), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 55/213 (26%), Positives = 79/213 (37%), Gaps = 56/213 (26%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCY- 97
PGD+VT+ C + V W + G P G L + +++ DSG Y+C
Sbjct 236 PGDNVTMQCSLTGGDPQPEVLW---SHSPGPLPPNSLVQGGNLTIWRIRVEDSGYYNCTA 292
Query 98 --RAGRPA-GTVHLLV------------DVPPE--------EPQLSCFRKS-PLSNVVCE 133
G PA TV+LLV DV E + +LSC + P VV
Sbjct 293 INNVGNPAKKTVNLLVRSMKNATFQITPDVIKESETIQLGQDLKLSCHVDAVPQEKVVYS 352
Query 134 WGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAVPEGDSSFYIVSMC 193
W P+ + L+ R N P E +C L + + S Y +C
Sbjct 353 WYKNGKPARFSDXXLITR---NDP------------ELPPVTCSLEIIDLRFSDYGTYLC 397
Query 194 VASSVGSKFSKTQTFQGCGILQPDPPANITVTA 226
VA TFQG I PD + +++
Sbjct 398 VA-----------TFQGAPI--PDLSVEVNISS 417
>2a0l_C C 33H1 Fv fragment
Length=105
Score = 32.3 bits (72), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 22/88 (25%), Positives = 39/88 (44%), Gaps = 21/88 (24%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ GD VT+TC ++ +HW +KP GS P W +G+ R
Sbjct 9 AIMSASLGDRVTMTCTASSSVSSSYLHWYQQKP--GSSPKLWIYSTSNLASGVPARFSGS 66
Query 81 -------LLLRSVQLHDSGNYSCYRAGR 101
L + S++ D+ Y C++ R
Sbjct 67 GSGTSYSLTISSMEAEDAATYYCHQFHR 94
>2a0l_E E 33H1 Fv fragment
Length=105
Score = 32.3 bits (72), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 22/88 (25%), Positives = 39/88 (44%), Gaps = 21/88 (24%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ GD VT+TC ++ +HW +KP GS P W +G+ R
Sbjct 9 AIMSASLGDRVTMTCTASSSVSSSYLHWYQQKP--GSSPKLWIYSTSNLASGVPARFSGS 66
Query 81 -------LLLRSVQLHDSGNYSCYRAGR 101
L + S++ D+ Y C++ R
Sbjct 67 GSGTSYSLTISSMEAEDAATYYCHQFHR 94
>1dqq_C C ANTI-LYSOZYME ANTIBODY HYHEL-63 (LIGHT CHAIN)
Length=214
Score = 33.9 bits (76), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>1dqm_A L ANTI-LYSOZYME ANTIBODY HYHEL-63 (LIGHT CHAIN)
Length=214
Score = 33.9 bits (76), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>1nby_A A antibody kappa light chain
Length=214
Score = 33.9 bits (76), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>1ndm_A A antibody kappa light chain
Length=214
Score = 33.9 bits (76), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>1dqq_A A ANTI-LYSOZYME ANTIBODY HYHEL-63 (LIGHT CHAIN)
Length=214
Score = 33.9 bits (76), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>1dqj_A A ANTI-LYSOZYME ANTIBODY HYHEL-63 (LIGHT CHAIN)
Length=214
Score = 33.9 bits (76), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>1ndg_A A antibody kappa light chain
Length=214
Score = 33.9 bits (76), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>1nbz_A A antibody kappa light chain
Length=214
Score = 33.9 bits (76), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>1xgu_A A antibody kappa light chain
Length=214
Score = 33.9 bits (76), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>2zkh_A L Monoclonal TN1 FAB light chain
Length=213
Score = 33.9 bits (76), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 27/111 (24%), Positives = 46/111 (41%), Gaps = 23/111 (21%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRWAGMGR 79
G++++ PG+ VT+TC + ++W +KP A P+R+ G G
Sbjct 9 GIMSASPGEKVTITCSA--SSSVSYMYWFQQKPGTSPKLWIYSTSNLASGVPARFRGSGS 66
Query 80 ----RLLLRSVQLHDSGNYSC-YRAGRP---AGTVHLLVDVPPEEPQLSCF 122
L + ++ D+ Y C R+G P G L + P +S F
Sbjct 67 GTSYSLTISRMEAEDAATYYCQQRSGYPRTFGGGTKLEIKRADAAPTVSIF 117
>1cd9_B B PROTEIN (G-CSF RECEPTOR)
Length=215
Score = 33.9 bits (76), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 48/210 (23%), Positives = 81/210 (39%), Gaps = 22/210 (10%)
Query 113 PPEEP-QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQES 171
PP P LSC +++VC+W P L T +L + F++ +Q +
Sbjct 4 PPASPSNLSCLMHLTTNSLVCQWEPGPETHLPTSFIL--KSFRSRADCQYQGDTIPDCVA 61
Query 172 QKFSCQLAVPEGDSSFY---IVSMCVASSVGSKFSKTQTFQGCGILQPDPPA----NITV 224
+K ++P + Y + + + +GS S +++ +PP +I
Sbjct 62 KKRQNNCSIPRKNLLLYQYMAIWVQAENMLGSSESPKLCLDPMDVVKLEPPMLQALDIXX 121
Query 225 TAVARNPRWLSVTWQDPHSWN-SSFYRLRFELRYR-----AERSKTFTTWMVKDLQHHCV 278
P L ++W+ W S + ELRY+ A + F KD C
Sbjct 122 XXXXXQPGCLWLSWK---PWKPSEYMEQECELRYQPQLKGANWTLVFHLPSSKDQFELCG 178
Query 279 IHDAWSGLRHVVQLRAQEEFGQGEWSEWSP 308
+H A + +Q+R G WS WSP
Sbjct 179 LHQA---PVYTLQMRCIRSSLPGFWSPWSP 205
>6gc2_A L Light Chain
Length=252
Score = 34.3 bits (77), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 35/130 (27%), Positives = 52/130 (40%), Gaps = 36/130 (28%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 29 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHEPPRLLIKYVSQSVSGIPSRFSGSGSG 87
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVD----------VPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + PP + QL
Sbjct 88 TDFTLSINSVETEDFGMYFCGQSNSWPRTFGGGTKLEIKRTVAAPSVFIFPPSDEQL--- 144
Query 123 RKSPLSNVVC 132
KS ++VVC
Sbjct 145 -KSGTASVVC 153
>1xgr_A A antibody kappa light chain
Length=215
Score = 33.9 bits (76), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 11 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 69
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 70 TDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 119
>1xgp_A A antibody kappa light chain
Length=215
Score = 33.9 bits (76), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 11 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 69
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 70 TDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 119
>1xgq_A A antibody kappa light chain
Length=215
Score = 33.9 bits (76), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 11 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 69
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 70 TDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 119
>1xgt_A A antibody kappa light chain
Length=215
Score = 33.9 bits (76), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 11 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 69
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 70 TDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 119
>1v7n_A L Monoclonal TN1 Fab Light Chain
Length=213
Score = 33.9 bits (76), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 27/111 (24%), Positives = 46/111 (41%), Gaps = 23/111 (21%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRWAGMGR 79
G++++ PG+ VT+TC + ++W +KP A P+R+ G G
Sbjct 9 GIMSASPGEKVTITCSA--SSSVSYMYWFQQKPGTSPKLWIYSTSNLASGVPARFRGSGS 66
Query 80 ----RLLLRSVQLHDSGNYSC-YRAGRP---AGTVHLLVDVPPEEPQLSCF 122
L + ++ D+ Y C R+G P G L + P +S F
Sbjct 67 GTSYSLTISRMEAEDAATYYCQQRSGYPRTFGGGTKLEIKRADAAPTVSIF 117
>1v7n_G O Monoclonal TN1 Fab Light Chain
Length=213
Score = 33.9 bits (76), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 27/111 (24%), Positives = 46/111 (41%), Gaps = 23/111 (21%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRWAGMGR 79
G++++ PG+ VT+TC + ++W +KP A P+R+ G G
Sbjct 9 GIMSASPGEKVTITCSA--SSSVSYMYWFQQKPGTSPKLWIYSTSNLASGVPARFRGSGS 66
Query 80 ----RLLLRSVQLHDSGNYSC-YRAGRP---AGTVHLLVDVPPEEPQLSCF 122
L + ++ D+ Y C R+G P G L + P +S F
Sbjct 67 GTSYSLTISRMEAEDAATYYCQQRSGYPRTFGGGTKLEIKRADAAPTVSIF 117
>6df0_A L 4G10-4D5 Antibody Light chain
Length=248
Score = 33.9 bits (76), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 35/128 (27%), Positives = 50/128 (39%), Gaps = 34/128 (27%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRW----AGM 77
L++ GD VT+TC ++ +HW +KP A PSR+ +G
Sbjct 34 LSASVGDRVTITCRASSSVSSSYLHWYQQKPGKAPKLLIYSTSNLASGVPSRFSGSRSGT 93
Query 78 GRRLLLRSVQLHDSGNYSC-----YRAGRPAGTVHLLVDV--------PPEEPQLSCFRK 124
L + S+Q D Y C YR V + V PP + QL K
Sbjct 94 DFTLTISSLQPEDFATYYCQQYSGYRTFGQGTKVEIKRTVAAPSVFIFPPSDSQL----K 149
Query 125 SPLSNVVC 132
S ++VVC
Sbjct 150 SGTASVVC 157
>7wvm_E D Light Chain of Cemiplimab
Length=107
Score = 32.3 bits (72), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 18/82 (22%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAA-------------GSHPSRWAGMGR-- 79
L++ GDS+T+TC N ++W +KP G PSR++G G
Sbjct 11 LSASVGDSITITCR-ASLSINTFLNWYQQKPGKAPNLLIYAASSLHGGVPSRFSGSGSGT 69
Query 80 --RLLLRSVQLHDSGNYSCYRA 99
L +R++Q D Y C ++
Sbjct 70 DFTLTIRTLQPEDFATYYCQQS 91
>7wvm_B B Light Chain of Cemiplimab
Length=107
Score = 32.3 bits (72), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 18/82 (22%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAA-------------GSHPSRWAGMGR-- 79
L++ GDS+T+TC N ++W +KP G PSR++G G
Sbjct 11 LSASVGDSITITCR-ASLSINTFLNWYQQKPGKAPNLLIYAASSLHGGVPSRFSGSGSGT 69
Query 80 --RLLLRSVQLHDSGNYSCYRA 99
L +R++Q D Y C ++
Sbjct 70 DFTLTIRTLQPEDFATYYCQQS 91
>7z3q_F F Leptin receptor
Length=232
Score = 33.9 bits (76), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 43/198 (22%), Positives = 79/198 (40%), Gaps = 12/198 (6%)
Query 118 QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNS-------PAEDFQEPCQYSQE 170
+SC L+ + C W ST + L +R ++S EP +
Sbjct 30 NISCETDGYLTKMTCRWS-TSTXXXXXXSTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQ 88
Query 171 SQKFSCQLAVPEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARN 230
S F + P S Y + + + S+GS S +++P PP+++ + N
Sbjct 89 SDGFYECIFQPIFLLSGYTMWIRIQHSLGSLDSPPTCVLPDSVVKPLPPSSVK-AEITIN 147
Query 231 PRWLSVTWQDP-HSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHV 289
L ++W+ P N+ +++R+ L + + K + + K + D +
Sbjct 148 IGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDL--SAVYA 205
Query 290 VQLRAQEEFGQGEWSEWS 307
VQ+R + G G WS WS
Sbjct 206 VQVRCKRLDGLGYWSNWS 223
>8g9y_F L vFP49.02 light chain
Length=214
Score = 33.9 bits (76), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 26/81 (32%), Positives = 37/81 (46%), Gaps = 20/81 (25%)
Query 34 VLTSLPGDSVTLTCPGVEP-EDNATVHWVLRKP-------------AAGSHPSRWAGMGR 79
L+ PGDSV+L+C + DN +HW L+K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQTISDN--LHWYLQKSHESPRLLIKYSSQSISGIPSRFSGSGS 67
Query 80 ----RLLLRSVQLHDSGNYSC 96
L + SV+ D G Y C
Sbjct 68 GTDFTLNINSVETEDFGMYFC 88
>8g9x_F L vFP49.02 light chain
Length=214
Score = 33.9 bits (76), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 26/81 (32%), Positives = 37/81 (46%), Gaps = 20/81 (25%)
Query 34 VLTSLPGDSVTLTCPGVEP-EDNATVHWVLRKP-------------AAGSHPSRWAGMGR 79
L+ PGDSV+L+C + DN +HW L+K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQTISDN--LHWYLQKSHESPRLLIKYSSQSISGIPSRFSGSGS 67
Query 80 ----RLLLRSVQLHDSGNYSC 96
L + SV+ D G Y C
Sbjct 68 GTDFTLNINSVETEDFGMYFC 88
>8g9w_F L vFP49.02 light chain
Length=214
Score = 33.9 bits (76), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 26/81 (32%), Positives = 37/81 (46%), Gaps = 20/81 (25%)
Query 34 VLTSLPGDSVTLTCPGVEP-EDNATVHWVLRKP-------------AAGSHPSRWAGMGR 79
L+ PGDSV+L+C + DN +HW L+K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQTISDN--LHWYLQKSHESPRLLIKYSSQSISGIPSRFSGSGS 67
Query 80 ----RLLLRSVQLHDSGNYSC 96
L + SV+ D G Y C
Sbjct 68 GTDFTLNINSVETEDFGMYFC 88
>8eq6_B L Antibody FAB light chain
Length=215
Score = 33.5 bits (75), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 34/129 (26%), Positives = 50/129 (39%), Gaps = 35/129 (27%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRWAGMGR-- 79
L++ GD VT+TC ++ +HW +KP A PSR++G G
Sbjct 11 LSASVGDRVTITCRASSSVISSYLHWYQQKPGKAPKLLIYSTSNLASGVPSRFSGSGSGT 70
Query 80 --RLLLRSVQLHDSGNYSCYRAGRP----AGTVHLLVD----------VPPEEPQLSCFR 123
L + S+Q D Y C + G L + PP + QL
Sbjct 71 DYTLTISSLQPEDFATYYCQQYNSYPLTFGGGTKLEIKRTVAAPSVFIFPPSDEQL---- 126
Query 124 KSPLSNVVC 132
KS ++VVC
Sbjct 127 KSGTASVVC 135
>6df1_A L Anti-phosphotyrosine antibody 4G10-4D5 heavy chain
Length=240
Score = 33.9 bits (76), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 35/128 (27%), Positives = 50/128 (39%), Gaps = 34/128 (27%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRW----AGM 77
L++ GD VT+TC ++ +HW +KP A PSR+ +G
Sbjct 34 LSASVGDRVTITCRASSSVSSSYLHWYQQKPGKAPKLLIYSTSNLASGVPSRFSGSRSGT 93
Query 78 GRRLLLRSVQLHDSGNYSC-----YRAGRPAGTVHLLVDV--------PPEEPQLSCFRK 124
L + S+Q D Y C YR V + V PP + QL K
Sbjct 94 DFTLTISSLQPEDFATYYCQQYSGYRTFGQGTKVEIKRTVAAPSVFIFPPSDSQL----K 149
Query 125 SPLSNVVC 132
S ++VVC
Sbjct 150 SGTASVVC 157
>6v4p_D D Abciximab, light chain
Length=214
Score = 33.5 bits (75), Expect = 3.3, Method: Compositional matrix adjust.
Identities = 38/130 (29%), Positives = 53/130 (41%), Gaps = 36/130 (28%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHW----------VLRKPAAGSH---PSRWAGMGR- 79
L+ PGDSV+L+C N +HW +L K A+ S PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASRDISN-NLHWFQQTSHESPRLLIKYASQSMSGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVD----------VPPEEPQLSCF 122
L + SV+ D G Y C + G L + PP + QL
Sbjct 69 TDFTLSINSVETEDFGMYFCQQTNSWPYTFGGGTKLEIKRTVAAPSVFIFPPSDEQL--- 125
Query 123 RKSPLSNVVC 132
KS ++VVC
Sbjct 126 -KSGTASVVC 134
>35c8_A L IGG 5C8
Length=212
Score = 33.5 bits (75), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 26/113 (23%), Positives = 46/113 (41%), Gaps = 25/113 (22%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ G+ VT+TC ++ +HW +KP GS P W +G+ R
Sbjct 9 AIMSASLGERVTMTCTASSSVSSSNLHWYQQKP--GSSPKLWIYSTSNLASGVPARFSGS 66
Query 81 -------LLLRSVQLHDSGNYSCYRAGRP----AGTVHLLVDVPPEEPQLSCF 122
L + S++ D+ Y C++ R G L + P +S F
Sbjct 67 GSGTSYSLTISSMEAEDAATYYCHQYHRSPYTFGGGTKLEIKRADAAPTVSIF 119
>25c8_A L IGG 5C8
Length=212
Score = 33.5 bits (75), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 26/113 (23%), Positives = 46/113 (41%), Gaps = 25/113 (22%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ G+ VT+TC ++ +HW +KP GS P W +G+ R
Sbjct 9 AIMSASLGERVTMTCTASSSVSSSNLHWYQQKP--GSSPKLWIYSTSNLASGVPARFSGS 66
Query 81 -------LLLRSVQLHDSGNYSCYRAGRP----AGTVHLLVDVPPEEPQLSCF 122
L + S++ D+ Y C++ R G L + P +S F
Sbjct 67 GSGTSYSLTISSMEAEDAATYYCHQYHRSPYTFGGGTKLEIKRADAAPTVSIF 119
>15c8_A L IGG 5C8 FAB (LIGHT CHAIN)
Length=213
Score = 33.5 bits (75), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 26/113 (23%), Positives = 46/113 (41%), Gaps = 25/113 (22%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ G+ VT+TC ++ +HW +KP GS P W +G+ R
Sbjct 9 AIMSASLGERVTMTCTASSSVSSSNLHWYQQKP--GSSPKLWIYSTSNLASGVPARFSGS 66
Query 81 -------LLLRSVQLHDSGNYSCYRAGRP----AGTVHLLVDVPPEEPQLSCF 122
L + S++ D+ Y C++ R G L + P +S F
Sbjct 67 GSGTSYSLTISSMEAEDAATYYCHQYHRSPYTFGGGTKLEIKRADAAPTVSIF 119
>4ffv_C C 11A19 Fab light chain
Length=210
Score = 33.5 bits (75), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 30/113 (27%), Positives = 47/113 (42%), Gaps = 27/113 (24%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
+L++ PG+ VT+TC +N +HW +KP GS P W +G+ R
Sbjct 9 AILSASPGEKVTMTCRASSSVNN--MHWYQQKP--GSSPKPWLHGTSNLASGVPVRFSGS 64
Query 81 -------LLLRSVQLHDSGNYSCYR-AGRP---AGTVHLLVDVPPEEPQLSCF 122
L + V+ D+ Y C + + P G L +D P +S F
Sbjct 65 GSGTSFSLTISRVEAEDAATYFCQQWSNHPPTFGGGTKLEIDRADAAPTVSIF 117
>4ffv_E L 11A19 Fab light chain
Length=210
Score = 33.5 bits (75), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 30/113 (27%), Positives = 47/113 (42%), Gaps = 27/113 (24%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
+L++ PG+ VT+TC +N +HW +KP GS P W +G+ R
Sbjct 9 AILSASPGEKVTMTCRASSSVNN--MHWYQQKP--GSSPKPWLHGTSNLASGVPVRFSGS 64
Query 81 -------LLLRSVQLHDSGNYSCYR-AGRP---AGTVHLLVDVPPEEPQLSCF 122
L + V+ D+ Y C + + P G L +D P +S F
Sbjct 65 GSGTSFSLTISRVEAEDAATYFCQQWSNHPPTFGGGTKLEIDRADAAPTVSIF 117
>1bm3_A L IMMUNOGLOBULIN OPG2 FAB, CONSTANT DOMAIN
Length=214
Score = 33.5 bits (75), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 24/83 (29%), Positives = 37/83 (45%), Gaps = 18/83 (22%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRA 99
L + SV+ D G Y C ++
Sbjct 69 TDFTLSINSVETEDFGMYFCQQS 91
>1opg_A L OPG2 FAB (LIGHT CHAIN)
Length=214
Score = 33.5 bits (75), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 24/83 (29%), Positives = 37/83 (45%), Gaps = 18/83 (22%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISN-NLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRA 99
L + SV+ D G Y C ++
Sbjct 69 TDFTLSINSVETEDFGMYFCQQS 91
>6u6u_B L BI00655130 Fab light chain
Length=215
Score = 33.5 bits (75), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 33/131 (25%), Positives = 51/131 (39%), Gaps = 35/131 (27%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRWAGMGR 79
G L+ PG+ T+TC ++ HW +KP A P R++G G
Sbjct 9 GTLSLSPGERATMTCTASSSVSSSYFHWYQQKPGQAPRLWIYRTSRLASGVPDRFSGSGS 68
Query 80 ----RLLLRSVQLHDSGNYSCYRAGRP-----AGTVHLL---------VDVPPEEPQLSC 121
L + ++ D+ Y C++ R AGT + PP + QL
Sbjct 69 GTDFTLTISRLEPEDAATYYCHQFHRSPLTFGAGTKLEIKRTVAAPSVFIFPPSDEQL-- 126
Query 122 FRKSPLSNVVC 132
KS ++VVC
Sbjct 127 --KSGTASVVC 135
>6djp_D D 8B8 light chain Fab
Length=213
Score = 33.1 bits (74), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 20/85 (24%), Positives = 39/85 (46%), Gaps = 23/85 (27%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ PG+ VT+TC + +HW +K +G+ P RW +G+ R
Sbjct 9 AIMSAFPGEKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRWIYDTSKLASGVPARFSGS 64
Query 81 -------LLLRSVQLHDSGNYSCYR 98
L + S++ D+ Y C++
Sbjct 65 GSGTSYSLTISSMEAEDAATYYCHQ 89
>5opy_B L Light chain of LM609 Fab (antigen-binding fragment)
Length=214
Score = 33.1 bits (74), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISNH-LHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGMYFCQQSNSWPHTFGGGTKLEIKRADAAPTVSIF 118
>1ors_A A 33H1 Fab light chain
Length=214
Score = 33.1 bits (74), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 22/88 (25%), Positives = 39/88 (44%), Gaps = 21/88 (24%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ GD VT+TC ++ +HW +KP GS P W +G+ R
Sbjct 9 AIMSASLGDRVTMTCTASSSVSSSYLHWYQQKP--GSSPKLWIYSTSNLASGVPARFSGS 66
Query 81 -------LLLRSVQLHDSGNYSCYRAGR 101
L + S++ D+ Y C++ R
Sbjct 67 GSGTSYSLTISSMEAEDAATYYCHQFHR 94
>6avu_D L Fab LM609 light chain
Length=214
Score = 33.1 bits (74), Expect = 4.4, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISNH-LHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGMYFCQQSNSWPHTFGGGTKLEIKRADAAPTVSIF 118
>6avr_D L Fab LM609 light chain
Length=214
Score = 33.1 bits (74), Expect = 4.4, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISNH-LHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGMYFCQQSNSWPHTFGGGTKLEIKRADAAPTVSIF 118
>6avq_D L LM609 Fab light chain
Length=214
Score = 33.1 bits (74), Expect = 4.4, Method: Compositional matrix adjust.
Identities = 29/110 (26%), Positives = 44/110 (40%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISNH-LHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLSINSVETEDFGMYFCQQSNSWPHTFGGGTKLEIKRADAAPTVSIF 118
>2brr_B L MN20B9.34 ANTI-P1.4 ANTIBODY, FAB LIGHT CHAIN
Length=215
Score = 33.1 bits (74), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 27/113 (24%), Positives = 48/113 (42%), Gaps = 25/113 (22%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ PG+ VT+TC ++ +HW +K +G+ P W +G+ R
Sbjct 9 AIMSASPGEKVTMTCRASSSVSSSYLHWYQQK--SGASPKLWIYSTSNLASGVPARFSGS 66
Query 81 -------LLLRSVQLHDSGNYSCYR-AGRP---AGTVHLLVDVPPEEPQLSCF 122
L + SV+ D+ Y C + +G P G L + P +S F
Sbjct 67 GSGTSYSLTISSVEAEDAATYYCQQYSGYPYTFGGGTKLEIKRADAAPTVSIF 119
>6k7o_C C h128-3 Fab light chain
Length=218
Score = 33.1 bits (74), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 23/82 (28%), Positives = 36/82 (44%), Gaps = 17/82 (21%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRWAGMGR-- 79
L++ GD VT+TC E ++ + W +KP A PSR++G G
Sbjct 11 LSASVGDRVTITCQASESINSIYLAWYQQKPGKAPKLLIYRASTLASGVPSRFSGSGSGT 70
Query 80 --RLLLRSVQLHDSGNYSCYRA 99
L + S+Q D Y C ++
Sbjct 71 DFTLTISSLQPEDFATYYCQQS 92
>6k7o_I L h128-3 Fab light chain
Length=218
Score = 33.1 bits (74), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 23/82 (28%), Positives = 36/82 (44%), Gaps = 17/82 (21%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRWAGMGR-- 79
L++ GD VT+TC E ++ + W +KP A PSR++G G
Sbjct 11 LSASVGDRVTITCQASESINSIYLAWYQQKPGKAPKLLIYRASTLASGVPSRFSGSGSGT 70
Query 80 --RLLLRSVQLHDSGNYSCYRA 99
L + S+Q D Y C ++
Sbjct 71 DFTLTISSLQPEDFATYYCQQS 92
>6k7o_E E h128-3 Fab light chain
Length=218
Score = 33.1 bits (74), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 23/82 (28%), Positives = 36/82 (44%), Gaps = 17/82 (21%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRWAGMGR-- 79
L++ GD VT+TC E ++ + W +KP A PSR++G G
Sbjct 11 LSASVGDRVTITCQASESINSIYLAWYQQKPGKAPKLLIYRASTLASGVPSRFSGSGSGT 70
Query 80 --RLLLRSVQLHDSGNYSCYRA 99
L + S+Q D Y C ++
Sbjct 71 DFTLTISSLQPEDFATYYCQQS 92
>6k7o_G G h128-3 Fab light chain
Length=218
Score = 33.1 bits (74), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 23/82 (28%), Positives = 36/82 (44%), Gaps = 17/82 (21%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRWAGMGR-- 79
L++ GD VT+TC E ++ + W +KP A PSR++G G
Sbjct 11 LSASVGDRVTITCQASESINSIYLAWYQQKPGKAPKLLIYRASTLASGVPSRFSGSGSGT 70
Query 80 --RLLLRSVQLHDSGNYSCYRA 99
L + S+Q D Y C ++
Sbjct 71 DFTLTISSLQPEDFATYYCQQS 92
>2brr_D X MN20B9.34 ANTI-P1.4 ANTIBODY, FAB LIGHT CHAIN
Length=215
Score = 33.1 bits (74), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 27/113 (24%), Positives = 48/113 (42%), Gaps = 25/113 (22%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ PG+ VT+TC ++ +HW +K +G+ P W +G+ R
Sbjct 9 AIMSASPGEKVTMTCRASSSVSSSYLHWYQQK--SGASPKLWIYSTSNLASGVPARFSGS 66
Query 81 -------LLLRSVQLHDSGNYSCYR-AGRP---AGTVHLLVDVPPEEPQLSCF 122
L + SV+ D+ Y C + +G P G L + P +S F
Sbjct 67 GSGTSYSLTISSVEAEDAATYYCQQYSGYPYTFGGGTKLEIKRADAAPTVSIF 119
>8dua_H E ITS92.02 Light Chain
Length=214
Score = 33.1 bits (74), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 26/79 (33%), Positives = 38/79 (48%), Gaps = 18/79 (23%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKP----------AAGSH---PSRWAGMGR-- 79
L++ GD VT+TC + DN ++W +KP A+ H PSR++G G
Sbjct 11 LSASVGDRVTITCRASQGIDNY-LNWYQQKPGKAPKRLIFAASSLHNGVPSRFSGSGSGT 69
Query 80 --RLLLRSVQLHDSGNYSC 96
L + S+Q D G Y C
Sbjct 70 KFTLTISSLQPEDLGTYYC 88
>8dua_L K ITS92.02 Light Chain
Length=214
Score = 33.1 bits (74), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 26/79 (33%), Positives = 38/79 (48%), Gaps = 18/79 (23%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKP----------AAGSH---PSRWAGMGR-- 79
L++ GD VT+TC + DN ++W +KP A+ H PSR++G G
Sbjct 11 LSASVGDRVTITCRASQGIDNY-LNWYQQKPGKAPKRLIFAASSLHNGVPSRFSGSGSGT 69
Query 80 --RLLLRSVQLHDSGNYSC 96
L + S+Q D G Y C
Sbjct 70 KFTLTISSLQPEDLGTYYC 88
>8dua_D L ITS92.02 Light Chain
Length=214
Score = 33.1 bits (74), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 26/79 (33%), Positives = 38/79 (48%), Gaps = 18/79 (23%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKP----------AAGSH---PSRWAGMGR-- 79
L++ GD VT+TC + DN ++W +KP A+ H PSR++G G
Sbjct 11 LSASVGDRVTITCRASQGIDNY-LNWYQQKPGKAPKRLIFAASSLHNGVPSRFSGSGSGT 69
Query 80 --RLLLRSVQLHDSGNYSC 96
L + S+Q D G Y C
Sbjct 70 KFTLTISSLQPEDLGTYYC 88
>7rah_C C M2B10 Fab Light Chain
Length=214
Score = 32.7 bits (73), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 34/133 (26%), Positives = 55/133 (41%), Gaps = 39/133 (29%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
+L++ G+ VT+TC ++ +HW +KP GS P W +G+ R
Sbjct 8 AILSASLGERVTMTCTASSSVSSSYLHWYQQKP--GSSPKLWIYSTSNLASGVPARFSGS 65
Query 81 -------LLLRSVQLHDSGNYSCYRAGRP-----AGTVHLL---------VDVPPEEPQL 119
L + S++ D+ Y C++ R AGT + PP + QL
Sbjct 66 GSGTSYSLTISSMEAEDAATYYCHQYHRSPPTFGAGTKLEIKRTVAAPSVFIFPPSDEQL 125
Query 120 SCFRKSPLSNVVC 132
KS ++VVC
Sbjct 126 ----KSGTASVVC 134
>5gir_B L Light chain of Fab fragment
Length=234
Score = 33.1 bits (74), Expect = 5.5, Method: Compositional matrix adjust.
Identities = 24/85 (28%), Positives = 37/85 (44%), Gaps = 18/85 (21%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 29 ATLSVTPGDSVSLSCRASQRISN-NLHWYQQKSHESPRLLIRYTSQSISGIPSRFSGSGS 87
Query 80 ----RLLLRSVQLHDSGNYSCYRAG 100
L + SV+ D G Y C ++
Sbjct 88 GTDFTLSINSVETEDFGMYFCQQSN 112
>5gir_D B Light chain of Fab fragment
Length=234
Score = 33.1 bits (74), Expect = 5.6, Method: Compositional matrix adjust.
Identities = 24/85 (28%), Positives = 37/85 (44%), Gaps = 18/85 (21%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 29 ATLSVTPGDSVSLSCRASQRISN-NLHWYQQKSHESPRLLIRYTSQSISGIPSRFSGSGS 87
Query 80 ----RLLLRSVQLHDSGNYSCYRAG 100
L + SV+ D G Y C ++
Sbjct 88 GTDFTLSINSVETEDFGMYFCQQSN 112
>5gis_B L Light chain of Fab fragment
Length=234
Score = 33.1 bits (74), Expect = 5.6, Method: Compositional matrix adjust.
Identities = 24/85 (28%), Positives = 37/85 (44%), Gaps = 18/85 (21%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR 79
L+ PGDSV+L+C + N +HW +K + PSR++G G
Sbjct 29 ATLSVTPGDSVSLSCRASQRISN-NLHWYQQKSHESPRLLIRYTSQSISGIPSRFSGSGS 87
Query 80 ----RLLLRSVQLHDSGNYSCYRAG 100
L + SV+ D G Y C ++
Sbjct 88 GTDFTLSINSVETEDFGMYFCQQSN 112
>3iu3_F L Light chain of Fab fragment of Basiliximab
Length=210
Score = 32.7 bits (73), Expect = 5.6, Method: Compositional matrix adjust.
Identities = 31/131 (24%), Positives = 53/131 (40%), Gaps = 39/131 (30%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ PG+ VT+TC + + W +KP G+ P RW +G+ R
Sbjct 9 AIMSASPGEKVTMTCSA--SSSRSYMQWYQQKP--GTSPKRWIYDTSKLASGVPARFSGS 64
Query 81 -------LLLRSVQLHDSGNYSCYRAGRP--AGTVHLLVD----------VPPEEPQLSC 121
L + S++ D+ Y C++ G L + PP + QL
Sbjct 65 GSGTSYSLTISSMEAEDAATYYCHQRSSYTFGGGTKLEIKRTVAAPSVFIFPPSDEQL-- 122
Query 122 FRKSPLSNVVC 132
KS ++VVC
Sbjct 123 --KSGTASVVC 131
>3iu3_B B Light chain of Fab fragment of Basiliximab
Length=210
Score = 32.7 bits (73), Expect = 5.6, Method: Compositional matrix adjust.
Identities = 31/131 (24%), Positives = 53/131 (40%), Gaps = 39/131 (30%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ PG+ VT+TC + + W +KP G+ P RW +G+ R
Sbjct 9 AIMSASPGEKVTMTCSA--SSSRSYMQWYQQKP--GTSPKRWIYDTSKLASGVPARFSGS 64
Query 81 -------LLLRSVQLHDSGNYSCYRAGRP--AGTVHLLVD----------VPPEEPQLSC 121
L + S++ D+ Y C++ G L + PP + QL
Sbjct 65 GSGTSYSLTISSMEAEDAATYYCHQRSSYTFGGGTKLEIKRTVAAPSVFIFPPSDEQL-- 122
Query 122 FRKSPLSNVVC 132
KS ++VVC
Sbjct 123 --KSGTASVVC 131
>6vvu_F F Fab E104.v1 light chain
Length=217
Score = 32.7 bits (73), Expect = 5.6, Method: Compositional matrix adjust.
Identities = 34/131 (26%), Positives = 51/131 (39%), Gaps = 37/131 (28%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAG-------------SHPSRWAGMGR-- 79
L++ GD VT+TC ++ N + W +KP PSR++G G
Sbjct 11 LSASVGDRVTITCQSIKSVYNNRLGWYQQKPGKAPKLLIYETSILTSGVPSRFSGSGSGT 70
Query 80 --RLLLRSVQLHDSGNYSCY----RAGRPAGTVHLLVDV------------PPEEPQLSC 121
L + S+Q D Y C R+G V++ PP + QL
Sbjct 71 DFTLTISSLQPEDFATYYCAGGFDRSGDTTFGQGTKVEIKRTVAAPSVFIFPPSDEQL-- 128
Query 122 FRKSPLSNVVC 132
KS ++VVC
Sbjct 129 --KSGTASVVC 137
>6vvu_I I Fab E104.v1 light chain
Length=217
Score = 32.7 bits (73), Expect = 5.6, Method: Compositional matrix adjust.
Identities = 34/131 (26%), Positives = 51/131 (39%), Gaps = 37/131 (28%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAG-------------SHPSRWAGMGR-- 79
L++ GD VT+TC ++ N + W +KP PSR++G G
Sbjct 11 LSASVGDRVTITCQSIKSVYNNRLGWYQQKPGKAPKLLIYETSILTSGVPSRFSGSGSGT 70
Query 80 --RLLLRSVQLHDSGNYSCY----RAGRPAGTVHLLVDV------------PPEEPQLSC 121
L + S+Q D Y C R+G V++ PP + QL
Sbjct 71 DFTLTISSLQPEDFATYYCAGGFDRSGDTTFGQGTKVEIKRTVAAPSVFIFPPSDEQL-- 128
Query 122 FRKSPLSNVVC 132
KS ++VVC
Sbjct 129 --KSGTASVVC 137
>7shz_E L HAE Variable fragment Light chain
Length=135
Score = 32.0 bits (71), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 20/85 (24%)
Query 35 LTSLPGDSVTLTCPGVEP---EDNATVHWVLRKPA--------AGSH-----PSRWAGMG 78
L++ GD VT+TC +P E ++ ++W +KP A S+ PSR++G G
Sbjct 14 LSASVGDRVTITCRASKPVDGEGDSYLNWYQQKPGKAPKLLIYAASYLESGVPSRFSGSG 73
Query 79 R----RLLLRSVQLHDSGNYSCYRA 99
L + S+Q D Y C ++
Sbjct 74 SGTDFTLTISSLQPEDFATYYCQQS 98
>7shz_G J HAE Variable fragment Light chain
Length=135
Score = 32.0 bits (71), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 20/85 (24%)
Query 35 LTSLPGDSVTLTCPGVEP---EDNATVHWVLRKPA--------AGSH-----PSRWAGMG 78
L++ GD VT+TC +P E ++ ++W +KP A S+ PSR++G G
Sbjct 14 LSASVGDRVTITCRASKPVDGEGDSYLNWYQQKPGKAPKLLIYAASYLESGVPSRFSGSG 73
Query 79 R----RLLLRSVQLHDSGNYSCYRA 99
L + S+Q D Y C ++
Sbjct 74 SGTDFTLTISSLQPEDFATYYCQQS 98
>1rvf_E L FAB 17-IA
Length=110
Score = 31.6 bits (70), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 13/42 (31%), Positives = 23/42 (55%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PG+ VT+TC + +HW +KP G+ P W
Sbjct 9 AIMSAFPGEKVTITCSATSSVNY--MHWFQQKP--GTSPKLW 46
>6vvu_L L Fab E104.v1 light chain
Length=217
Score = 32.7 bits (73), Expect = 5.8, Method: Compositional matrix adjust.
Identities = 34/131 (26%), Positives = 51/131 (39%), Gaps = 37/131 (28%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAG-------------SHPSRWAGMGR-- 79
L++ GD VT+TC ++ N + W +KP PSR++G G
Sbjct 11 LSASVGDRVTITCQSIKSVYNNRLGWYQQKPGKAPKLLIYETSILTSGVPSRFSGSGSGT 70
Query 80 --RLLLRSVQLHDSGNYSCY----RAGRPAGTVHLLVDV------------PPEEPQLSC 121
L + S+Q D Y C R+G V++ PP + QL
Sbjct 71 DFTLTISSLQPEDFATYYCAGGFDRSGDTTFGQGTKVEIKRTVAAPSVFIFPPSDEQL-- 128
Query 122 FRKSPLSNVVC 132
KS ++VVC
Sbjct 129 --KSGTASVVC 137
>1mim_A L CHIMERIC SDZ CHI621
Length=210
Score = 32.7 bits (73), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 31/131 (24%), Positives = 53/131 (40%), Gaps = 39/131 (30%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ PG+ VT+TC + + W +KP G+ P RW +G+ R
Sbjct 9 AIMSASPGEKVTMTCSA--SSSRSYMQWYQQKP--GTSPKRWIYDTSKLASGVPARFSGS 64
Query 81 -------LLLRSVQLHDSGNYSCYRAGRP--AGTVHLLVD----------VPPEEPQLSC 121
L + S++ D+ Y C++ G L + PP + QL
Sbjct 65 GSGTSYSLTISSMEAEDAATYYCHQRSSYTFGGGTKLEIKRTVAAPSVFIFPPSDEQL-- 122
Query 122 FRKSPLSNVVC 132
KS ++VVC
Sbjct 123 --KSGTASVVC 131
>1fnl_A A LOW AFFINITY IMMUNOGLOBULIN GAMMA FC REGION RECEPTOR
III-B
Length=175
Score = 32.3 bits (72), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 21/60 (35%), Positives = 28/60 (47%), Gaps = 9/60 (15%)
Query 38 LPGDSVTLTCPGV-EPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSC 96
L DSVTL C G PEDN+T W + S S + + + ++DSG Y C
Sbjct 20 LEKDSVTLKCQGAYSPEDNST-QWFHNESLISSQASSY-------FIDAATVNDSGEYRC 71
>6df2_D A Anti-phosphotyrosine antibody c310-4D5 heavy chain
Length=251
Score = 33.1 bits (74), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 35/131 (27%), Positives = 50/131 (38%), Gaps = 37/131 (28%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRW----AGM 77
L++ GD VT+TC ++ +HW +KP A PSR+ +G
Sbjct 34 LSASVGDRVTITCRASSSVSSSYLHWYQQKPGKAPKLLIYSTSNLASGVPSRFSGSRSGT 93
Query 78 GRRLLLRSVQLHDSGNYSC--------YRAGRPAGTVHLLVDV--------PPEEPQLSC 121
L + S+Q D Y C YR V + V PP + QL
Sbjct 94 DFTLTISSLQPEDFATYYCQQYSRRTSYRTFGQGTKVEIKRTVAAPSVFIFPPSDSQL-- 151
Query 122 FRKSPLSNVVC 132
KS ++VVC
Sbjct 152 --KSGTASVVC 160
>6df2_A L Anti-phosphotyrosine antibody c310-4D5 heavy chain
Length=251
Score = 33.1 bits (74), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 35/131 (27%), Positives = 50/131 (38%), Gaps = 37/131 (28%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPA-------------AGSHPSRW----AGM 77
L++ GD VT+TC ++ +HW +KP A PSR+ +G
Sbjct 34 LSASVGDRVTITCRASSSVSSSYLHWYQQKPGKAPKLLIYSTSNLASGVPSRFSGSRSGT 93
Query 78 GRRLLLRSVQLHDSGNYSC--------YRAGRPAGTVHLLVDV--------PPEEPQLSC 121
L + S+Q D Y C YR V + V PP + QL
Sbjct 94 DFTLTISSLQPEDFATYYCQQYSRRTSYRTFGQGTKVEIKRTVAAPSVFIFPPSDSQL-- 151
Query 122 FRKSPLSNVVC 132
KS ++VVC
Sbjct 152 --KSGTASVVC 160
>6vvu_K K Fab E104.v1 light chain
Length=217
Score = 32.7 bits (73), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 34/131 (26%), Positives = 51/131 (39%), Gaps = 37/131 (28%)
Query 35 LTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAG-------------SHPSRWAGMGR-- 79
L++ GD VT+TC ++ N + W +KP PSR++G G
Sbjct 11 LSASVGDRVTITCQSIKSVYNNRLGWYQQKPGKAPKLLIYETSILTSGVPSRFSGSGSGT 70
Query 80 --RLLLRSVQLHDSGNYSCY----RAGRPAGTVHLLVDV------------PPEEPQLSC 121
L + S+Q D Y C R+G V++ PP + QL
Sbjct 71 DFTLTISSLQPEDFATYYCAGGFDRSGDTTFGQGTKVEIKRTVAAPSVFIFPPSDEQL-- 128
Query 122 FRKSPLSNVVC 132
KS ++VVC
Sbjct 129 --KSGTASVVC 137
>7cw3_TA p Fab light chain
Length=213
Score = 32.7 bits (73), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 30/111 (27%), Positives = 45/111 (41%), Gaps = 24/111 (22%)
Query 34 VLTSLPGDSVTLTCPGVEP-EDNATVHWVLRKP-------------AAGSHPSRWAGMGR 79
L+ PGDSV+L+C + DN +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISDN--LHWYQQKSHESPGLLIKYASQSISGIPSRFSGSGS 67
Query 80 ----RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 68 GTDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>7cw3_GA n Fab light chain
Length=213
Score = 32.7 bits (73), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 30/111 (27%), Positives = 45/111 (41%), Gaps = 24/111 (22%)
Query 34 VLTSLPGDSVTLTCPGVEP-EDNATVHWVLRKP-------------AAGSHPSRWAGMGR 79
L+ PGDSV+L+C + DN +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISDN--LHWYQQKSHESPGLLIKYASQSISGIPSRFSGSGS 67
Query 80 ----RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 68 GTDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>7cw3_W l Fab light chain
Length=213
Score = 32.7 bits (73), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 30/111 (27%), Positives = 45/111 (41%), Gaps = 24/111 (22%)
Query 34 VLTSLPGDSVTLTCPGVEP-EDNATVHWVLRKP-------------AAGSHPSRWAGMGR 79
L+ PGDSV+L+C + DN +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISDN--LHWYQQKSHESPGLLIKYASQSISGIPSRFSGSGS 67
Query 80 ----RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 68 GTDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>7cw3_J r Fab light chain
Length=213
Score = 32.7 bits (73), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 30/111 (27%), Positives = 45/111 (41%), Gaps = 24/111 (22%)
Query 34 VLTSLPGDSVTLTCPGVEP-EDNATVHWVLRKP-------------AAGSHPSRWAGMGR 79
L+ PGDSV+L+C + DN +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISDN--LHWYQQKSHESPGLLIKYASQSISGIPSRFSGSGS 67
Query 80 ----RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 68 GTDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>7cw2_V V Fab light chain
Length=213
Score = 32.7 bits (73), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 30/111 (27%), Positives = 45/111 (41%), Gaps = 24/111 (22%)
Query 34 VLTSLPGDSVTLTCPGVEP-EDNATVHWVLRKP-------------AAGSHPSRWAGMGR 79
L+ PGDSV+L+C + DN +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISDN--LHWYQQKSHESPGLLIKYASQSISGIPSRFSGSGS 67
Query 80 ----RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 68 GTDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>7cw2_K T Fab light chain
Length=213
Score = 32.7 bits (73), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 30/111 (27%), Positives = 45/111 (41%), Gaps = 24/111 (22%)
Query 34 VLTSLPGDSVTLTCPGVEP-EDNATVHWVLRKP-------------AAGSHPSRWAGMGR 79
L+ PGDSV+L+C + DN +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISDN--LHWYQQKSHESPGLLIKYASQSISGIPSRFSGSGS 67
Query 80 ----RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 68 GTDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>7cw0_M R Fab light chain
Length=213
Score = 32.7 bits (73), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 30/111 (27%), Positives = 45/111 (41%), Gaps = 24/111 (22%)
Query 34 VLTSLPGDSVTLTCPGVEP-EDNATVHWVLRKP-------------AAGSHPSRWAGMGR 79
L+ PGDSV+L+C + DN +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISDN--LHWYQQKSHESPGLLIKYASQSISGIPSRFSGSGS 67
Query 80 ----RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 68 GTDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>7cw0_E P Fab light chain
Length=213
Score = 32.7 bits (73), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 30/111 (27%), Positives = 45/111 (41%), Gaps = 24/111 (22%)
Query 34 VLTSLPGDSVTLTCPGVEP-EDNATVHWVLRKP-------------AAGSHPSRWAGMGR 79
L+ PGDSV+L+C + DN +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISDN--LHWYQQKSHESPGLLIKYASQSISGIPSRFSGSGS 67
Query 80 ----RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 68 GTDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>7cvz_M R Fab light chain
Length=213
Score = 32.7 bits (73), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 30/111 (27%), Positives = 45/111 (41%), Gaps = 24/111 (22%)
Query 34 VLTSLPGDSVTLTCPGVEP-EDNATVHWVLRKP-------------AAGSHPSRWAGMGR 79
L+ PGDSV+L+C + DN +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISDN--LHWYQQKSHESPGLLIKYASQSISGIPSRFSGSGS 67
Query 80 ----RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 68 GTDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>7cvz_E P Fab light chain
Length=213
Score = 32.7 bits (73), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 30/111 (27%), Positives = 45/111 (41%), Gaps = 24/111 (22%)
Query 34 VLTSLPGDSVTLTCPGVEP-EDNATVHWVLRKP-------------AAGSHPSRWAGMGR 79
L+ PGDSV+L+C + DN +HW +K + PSR++G G
Sbjct 10 TLSVTPGDSVSLSCRASQSISDN--LHWYQQKSHESPGLLIKYASQSISGIPSRFSGSGS 67
Query 80 ----RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 68 GTDFTLSINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>5nj6_C L Fab3949 L
Length=213
Score = 32.7 bits (73), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 26/113 (23%), Positives = 46/113 (41%), Gaps = 25/113 (22%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ G+ VT+TC ++ +HW +KP GS P W +G+ R
Sbjct 9 AIMSASLGERVTMTCTASSSISSSYLHWYQQKP--GSSPKLWIYSTSNLASGVPARFSGS 66
Query 81 -------LLLRSVQLHDSGNYSCYRAGRP----AGTVHLLVDVPPEEPQLSCF 122
L + S++ D+ Y C++ R G L + P +S F
Sbjct 67 GSGTSYSLTISSMEAEDAATYYCHQFHRSPYTFGGGTKLEIKRADAAPTVSIF 119
>1orq_A A 6E1 Fab light chain
Length=215
Score = 32.7 bits (73), Expect = 6.3, Method: Compositional matrix adjust.
Identities = 27/113 (24%), Positives = 47/113 (42%), Gaps = 25/113 (22%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
+++ PG+ VT+TC ++ +HW +K +G+ P W +G+ R
Sbjct 9 AIMSPSPGEKVTMTCRARSSVSSSYLHWYQQK--SGASPKLWIYSTSNLASGVPARFSGS 66
Query 81 -------LLLRSVQLHDSGNYSCYR-AGRP---AGTVHLLVDVPPEEPQLSCF 122
L + SV+ D+ Y C + +G P G L + P +S F
Sbjct 67 GSGTSYSLTISSVEAEDTATYYCQQYSGNPWTFGGGTKLEIKRADAAPTVSIF 119
>3w2d_B L Monoclonal Antibody 3E2 Fab figment light chain
Length=215
Score = 32.7 bits (73), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 20/83 (24%), Positives = 37/83 (45%), Gaps = 21/83 (25%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ PG++VT+TC + +HW +K +G+ P W +G+ R
Sbjct 9 AIMSASPGETVTMTCRATSSVSSTYLHWYQQK--SGASPKLWIYSTSNLASGVPARFSGS 66
Query 81 -------LLLRSVQLHDSGNYSC 96
L + SV+ D+ Y C
Sbjct 67 GSGTSYSLTISSVEAEDAATYYC 89
>3iu3_D D Light chain of Fab fragment of Basiliximab
Length=210
Score = 32.7 bits (73), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 31/131 (24%), Positives = 53/131 (40%), Gaps = 39/131 (30%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ PG+ VT+TC + + W +KP G+ P RW +G+ R
Sbjct 9 AIMSASPGEKVTMTCSA--SSSRSYMQWYQQKP--GTSPKRWIYDTSKLASGVPARFSGS 64
Query 81 -------LLLRSVQLHDSGNYSCYRAGRP--AGTVHLLVD----------VPPEEPQLSC 121
L + S++ D+ Y C++ G L + PP + QL
Sbjct 65 GSGTSYSLTISSMEAEDAATYYCHQRSSYTFGGGTKLEIKRTVAAPSVFIFPPSDEQL-- 122
Query 122 FRKSPLSNVVC 132
KS ++VVC
Sbjct 123 --KSGTASVVC 131
>1pgr_F F PROTEIN (G-CSF RECEPTOR)
Length=215
Score = 32.7 bits (73), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 48/210 (23%), Positives = 80/210 (38%), Gaps = 22/210 (10%)
Query 113 PPEEP-QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQES 171
PP P LSC +++VC+W P L T +L + F++ +Q +
Sbjct 4 PPASPSNLSCLMHLTTNSLVCQWEPGPETHLPTSFIL--KSFRSRADCQYQGDTIPDCVA 61
Query 172 QKFSCQLAVPEGDSSFY---IVSMCVASSVGSKFSKTQTFQGCGILQPDPPA----NITV 224
+K ++P + Y + + + +GS S + + +PP +I
Sbjct 62 KKRQNNCSIPRKNLLLYQYMAIWVQAENMLGSSESPKLCLDPMDVXKLEPPMLQALDIGP 121
Query 225 TAVARNPRWLSVTWQDPHSWN-SSFYRLRFELRYR-----AERSKTFTTWMVKDLQHHCV 278
P L ++W+ W S + ELRY+ A + F KD C
Sbjct 122 DXXXHQPGCLWLSWK---PWKPSEYMEQECELRYQPQLKGANWTLVFHLPSSKDQFELCG 178
Query 279 IHDAWSGLRHVVQLRAQEEFGQGEWSEWSP 308
+H A + +Q+R G WS WSP
Sbjct 179 LHQA---PVYTLQMRCIRSSLPGFWSPWSP 205
>1ken_G L influenza virus infectivity neutralizing antibody (light
chain)
Length=213
Score = 32.7 bits (73), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 21/85 (25%), Positives = 39/85 (46%), Gaps = 21/85 (25%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ PG+ VTLTC ++ ++W +KP GS P W +G+ R
Sbjct 9 AIMSASPGEKVTLTCSASSTITSSFLYWYQQKP--GSSPKLWIYSTSNLASGVPARFSGS 66
Query 81 -------LLLRSVQLHDSGNYSCYR 98
L + S++ D +Y C++
Sbjct 67 GSGTSYSLTISSLEAEDGASYFCHQ 91
>1ken_I U influenza virus infectivity neutralizing antibody (light
chain)
Length=213
Score = 32.7 bits (73), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 21/85 (25%), Positives = 39/85 (46%), Gaps = 21/85 (25%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ PG+ VTLTC ++ ++W +KP GS P W +G+ R
Sbjct 9 AIMSASPGEKVTLTCSASSTITSSFLYWYQQKP--GSSPKLWIYSTSNLASGVPARFSGS 66
Query 81 -------LLLRSVQLHDSGNYSCYR 98
L + S++ D +Y C++
Sbjct 67 GSGTSYSLTISSLEAEDGASYFCHQ 91
>8iv8_D D light chain of 1C4
Length=107
Score = 31.2 bits (69), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 23/83 (28%), Positives = 37/83 (45%), Gaps = 18/83 (22%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGD+V+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDNVSLSCRASQIISN-NLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRA 99
L + SV+ D G Y C ++
Sbjct 69 TDFTLSINSVETEDFGMYFCQQS 91
>8iv5_D B light chain of 1C4
Length=107
Score = 31.2 bits (69), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 23/83 (28%), Positives = 37/83 (45%), Gaps = 18/83 (22%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
L+ PGD+V+L+C + N +HW +K + PSR++G G
Sbjct 10 TLSVTPGDNVSLSCRASQIISN-NLHWYQQKSHESPRLLIKYASQSISGIPSRFSGSGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRA 99
L + SV+ D G Y C ++
Sbjct 69 TDFTLSINSVETEDFGMYFCQQS 91
>7shz_L F HAE Variable fragment Light chain
Length=135
Score = 32.0 bits (71), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 25/82 (30%), Positives = 39/82 (48%), Gaps = 20/82 (24%)
Query 35 LTSLPGDSVTLTCPGVEP---EDNATVHWVLRKPA--------AGSH-----PSRWAGMG 78
L++ GD VT+TC +P E ++ ++W +KP A S+ PSR++G G
Sbjct 14 LSASVGDRVTITCRASKPVDGEGDSYLNWYQQKPGKAPKLLIYAASYLESGVPSRFSGSG 73
Query 79 R----RLLLRSVQLHDSGNYSC 96
L + S+Q D Y C
Sbjct 74 SGTDFTLTISSLQPEDFATYYC 95
>7shz_F D HAE Variable fragment Light chain
Length=135
Score = 32.0 bits (71), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 25/82 (30%), Positives = 39/82 (48%), Gaps = 20/82 (24%)
Query 35 LTSLPGDSVTLTCPGVEP---EDNATVHWVLRKPA--------AGSH-----PSRWAGMG 78
L++ GD VT+TC +P E ++ ++W +KP A S+ PSR++G G
Sbjct 14 LSASVGDRVTITCRASKPVDGEGDSYLNWYQQKPGKAPKLLIYAASYLESGVPSRFSGSG 73
Query 79 R----RLLLRSVQLHDSGNYSC 96
L + S+Q D Y C
Sbjct 74 SGTDFTLTISSLQPEDFATYYC 95
>1t89_C C Low affinity immunoglobulin gamma Fc region receptor
III-B
Length=176
Score = 32.3 bits (72), Expect = 6.9, Method: Compositional matrix adjust.
Identities = 21/60 (35%), Positives = 28/60 (47%), Gaps = 9/60 (15%)
Query 38 LPGDSVTLTCPGV-EPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSC 96
L DSVTL C G PEDN+T W + S S + + + ++DSG Y C
Sbjct 20 LEKDSVTLKCQGAYSPEDNST-QWFHNESLISSQASSY-------FIDAATVNDSGEYRC 71
>1t83_C C Low affinity immunoglobulin gamma Fc region receptor
III-B
Length=176
Score = 32.3 bits (72), Expect = 6.9, Method: Compositional matrix adjust.
Identities = 21/60 (35%), Positives = 28/60 (47%), Gaps = 9/60 (15%)
Query 38 LPGDSVTLTCPGV-EPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSC 96
L DSVTL C G PEDN+T W + S S + + + ++DSG Y C
Sbjct 20 LEKDSVTLKCQGAYSPEDNST-QWFHNESLISSQASSY-------FIDAATVNDSGEYRC 71
>1e4k_C C LOW AFFINITY IMMUNOGLOBULIN GAMMA FC RECEPTOR III
Length=176
Score = 32.3 bits (72), Expect = 6.9, Method: Compositional matrix adjust.
Identities = 21/60 (35%), Positives = 28/60 (47%), Gaps = 9/60 (15%)
Query 38 LPGDSVTLTCPGV-EPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSC 96
L DSVTL C G PEDN+T W + S S + + + ++DSG Y C
Sbjct 21 LEKDSVTLKCQGAYSPEDNST-QWFHNESLISSQASSY-------FIDAATVNDSGEYRC 72
>1e4j_A A LOW AFFINITY IMMUNOGLOBULIN GAMMA FC RECEPTOR III
Length=176
Score = 32.3 bits (72), Expect = 7.0, Method: Compositional matrix adjust.
Identities = 21/60 (35%), Positives = 28/60 (47%), Gaps = 9/60 (15%)
Query 38 LPGDSVTLTCPGV-EPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSC 96
L DSVTL C G PEDN+T W + S S + + + ++DSG Y C
Sbjct 21 LEKDSVTLKCQGAYSPEDNST-QWFHNESLISSQASSY-------FIDAATVNDSGEYRC 72
>5yc5_C C Low affinity immunoglobulin gamma Fc region receptor
III-A
Length=182
Score = 32.3 bits (72), Expect = 7.0, Method: Compositional matrix adjust.
Identities = 22/60 (37%), Positives = 28/60 (47%), Gaps = 9/60 (15%)
Query 38 LPGDSVTLTCPGV-EPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSC 96
L DSVTL C G PEDN+T W + S S + L+ + + DSG Y C
Sbjct 20 LEKDSVTLKCRGAYSPEDNST-QWFHNESLISSQASSY-------LIDAATVDDSGEYRC 71
>1x5h_A A Neogenin
Length=132
Score = 31.6 bits (70), Expect = 7.5, Method: Compositional matrix adjust.
Identities = 30/114 (26%), Positives = 49/114 (43%), Gaps = 8/114 (7%)
Query 219 PANITVTAVARNPRWLSVTWQDPHSWNSSFYRLRFELRYR-AERSKTFTTWMVKDLQHHC 277
P N+++ RN + + + WQ P + +++RYR A R T +V Q
Sbjct 22 PQNLSLEV--RNSKSIMIHWQPPAPATQNGQITGYKIRYRKASRKSDVTETLVSGTQLSQ 79
Query 278 VIHDAWSGLRHVVQLRAQEEFGQGEWSEW-SPEAMGTPWTESRSPPAENEVSTP 330
+I G + ++ A G G ++W S E + E+R P EVS P
Sbjct 80 LIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVP----EVSGP 129
>5mn2_B B Low affinity immunoglobulin gamma Fc region receptor
III-A
Length=175
Score = 32.0 bits (71), Expect = 7.8, Method: Compositional matrix adjust.
Identities = 21/60 (35%), Positives = 27/60 (45%), Gaps = 9/60 (15%)
Query 38 LPGDSVTLTCPGV-EPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSC 96
L DSVTL C G PEDN+T W + S S + + + + DSG Y C
Sbjct 20 LEKDSVTLKCQGAYSPEDNST-QWFHNESLISSQASSY-------FIDAATVDDSGEYRC 71
>7w71_D L Light chain of Fab
Length=214
Score = 32.3 bits (72), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 27/110 (25%), Positives = 46/110 (42%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
+L+ PGDSV+L+C + ++ +HW ++ + PSR++G G
Sbjct 10 ILSVTPGDSVSLSCRASQSV-SSNLHWYQQRSHESPRLLITYAFQSISGIPSRFSGNGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLNINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>6ada_D D antibody Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2r9h_D D Fab fragment
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>6adc_F F antibody Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>5hd8_D D FAB FRAGMENT (LIGHT CHAIN)
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kk5_D D Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>3det_D D Fab fragment, Light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>7cvt_F F antibody Fab fragment light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>6adc_D D antibody Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>5hd8_F F FAB FRAGMENT (LIGHT CHAIN)
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4mqx_D D ERIC
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4lou_F F Fab light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kka_D D Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kjp_F F light chain of Fab fragment
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>3det_F F Fab fragment, Light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>6ada_F F antibody Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>6adb_D D antibody Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>6adb_F F antibody Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>6ad7_D D antibody Fab fragment light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>6ad8_D D antibody Fab fragment light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>6ad7_F F antibody Fab fragment light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>6ad8_F F antibody Fab fragment light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4lou_D D Fab light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2r9h_F F Fab fragment
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>7cvt_D D antibody Fab fragment light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>7cvs_D D antibody Fab fragment light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>7cvs_F F antibody Fab fragment light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4fg6_F F Fab fragment (Light chain)
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4fg6_D D Fab fragment (Light chain)
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2fee_D O Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2fee_F L Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2fed_D D Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2fed_F F Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2fec_F L Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2fec_D O Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kjp_D D light chain of Fab fragment
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2ht2_D D Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kk8_D D Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2htl_D D Fab fragment, Light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2htl_F F Fab fragment, Light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2htk_D D Fab fragment, Light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2htk_F F Fab fragment, Light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2ht2_F F Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2ht3_D D Fab fragment, Light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2ht4_D D Fab fragment, Light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2ht3_F F Fab fragment, Light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2ht4_F F Fab fragment, Light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2ez0_F F Fab Fragment (Light Chain)
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2ez0_D D Fab Fragment (Light Chain)
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2exy_F F Fab Fragment (Light Chain)
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2exw_F F Fab Fragment (Light Chain)
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2exy_D D Fab Fragment (Light Chain)
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2exw_D D Fab Fragment (Light Chain)
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kkl_D D Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kkl_F F Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kkc_D D Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kkb_F F Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kkb_D D Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kkc_F F Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kka_F F Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kk8_F F Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kk9_D D Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kk9_F F Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kk5_F F Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kk6_F F Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kk6_D D Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kjw_F F Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kjw_D D Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kjq_F F Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4kjq_D D Fab, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>6k5i_D D Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>6k5a_D D Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>3ejy_D D Fab fragment, Light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2hlf_D D Fab Fragment, Light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>6k5f_D D Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>1ots_D D Fab fragment (light chain)
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>1otu_F F Fab fragment (Light chain)
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2hlf_F F Fab Fragment, Light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4ene_D D light chain of Fab fragment
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4ene_F F light chain of Fab fragment
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>3ejz_D D Fab fragment, Light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>3ejz_F F Fab fragment, Light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>3ejy_F F Fab fragment, Light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>6k5i_F F Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>6k5f_F F Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>6k5d_F F Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>6k5d_D D Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>6k5a_F F Fab fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>4mqx_F F ERIC
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2h2s_F F FAB fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2h2s_D D FAB fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2h2p_D D FAB fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>2h2p_F F FAB fragment, light chain
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>1otu_D D Fab fragment (Light chain)
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>1ott_F F Fab fragment (Light chain)
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>1ott_D D Fab fragment (Light chain)
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>1ots_F F Fab fragment (light chain)
Length=211
Score = 32.3 bits (72), Expect = 8.2, Method: Compositional matrix adjust.
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 4/42 (10%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW 74
++++ PGD VT+TC + +HW +K +G+ P RW
Sbjct 9 AIMSAAPGDKVTMTCSA--SSSVSYIHWYQQK--SGTSPKRW 46
>7w71_F M Light chain of Fab
Length=214
Score = 32.3 bits (72), Expect = 8.3, Method: Compositional matrix adjust.
Identities = 27/110 (25%), Positives = 46/110 (42%), Gaps = 22/110 (20%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKP-------------AAGSHPSRWAGMGR- 79
+L+ PGDSV+L+C + ++ +HW ++ + PSR++G G
Sbjct 10 ILSVTPGDSVSLSCRASQSV-SSNLHWYQQRSHESPRLLITYAFQSISGIPSRFSGNGSG 68
Query 80 ---RLLLRSVQLHDSGNYSCYRAGR----PAGTVHLLVDVPPEEPQLSCF 122
L + SV+ D G Y C ++ G L + P +S F
Sbjct 69 TDFTLNINSVETEDFGMYFCQQSNSWPYTFGGGTKLEIKRADAAPTVSIF 118
>2iff_A L IGG1 HYHEL-5 FAB (LIGHT CHAIN)
Length=212
Score = 32.3 bits (72), Expect = 8.6, Method: Compositional matrix adjust.
Identities = 26/112 (23%), Positives = 47/112 (42%), Gaps = 26/112 (23%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ PG+ VT+TC + ++W +K +G+ P RW +G+ R
Sbjct 9 AIMSASPGEKVTMTCSASSSVN--YMYWYQQK--SGTSPKRWIYDTSKLASGVPVRFSGS 64
Query 81 -------LLLRSVQLHDSGNYSCYRAGRP---AGTVHLLVDVPPEEPQLSCF 122
L + S++ D+ Y C + GR G L + P +S F
Sbjct 65 GSGTSYSLTISSMETEDAATYYCQQWGRNPTFGGGTKLEIKRADAAPTVSIF 116
>1bql_A L HYHEL-5 FAB (LIGHT CHAIN)
Length=212
Score = 32.3 bits (72), Expect = 8.6, Method: Compositional matrix adjust.
Identities = 26/112 (23%), Positives = 47/112 (42%), Gaps = 26/112 (23%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ PG+ VT+TC + ++W +K +G+ P RW +G+ R
Sbjct 9 AIMSASPGEKVTMTCSASSSVN--YMYWYQQK--SGTSPKRWIYDTSKLASGVPVRFSGS 64
Query 81 -------LLLRSVQLHDSGNYSCYRAGRP---AGTVHLLVDVPPEEPQLSCF 122
L + S++ D+ Y C + GR G L + P +S F
Sbjct 65 GSGTSYSLTISSMETEDAATYYCQQWGRNPTFGGGTKLEIKRADAAPTVSIF 116
>8iow_B D2 Interleukin-6 receptor subunit alpha
Length=365
Score = 32.7 bits (73), Expect = 8.7, Method: Compositional matrix adjust.
Identities = 14/14 (100%), Positives = 14/14 (100%), Gaps = 0/14 (0%)
Query 120 SCFRKSPLSNVVCE 133
SCFRKSPLSNVVCE
Sbjct 120 SCFRKSPLSNVVCE 133
>1yqv_A L HyHEL-5 Antibody Light Chain
Length=211
Score = 32.3 bits (72), Expect = 8.7, Method: Compositional matrix adjust.
Identities = 26/112 (23%), Positives = 47/112 (42%), Gaps = 26/112 (23%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ PG+ VT+TC + ++W +K +G+ P RW +G+ R
Sbjct 10 AIMSASPGEKVTMTCSASSSVN--YMYWYQQK--SGTSPKRWIYDTSKLASGVPVRFSGS 65
Query 81 -------LLLRSVQLHDSGNYSCYRAGRP---AGTVHLLVDVPPEEPQLSCF 122
L + S++ D+ Y C + GR G L + P +S F
Sbjct 66 GSGTSYSLTISSMETEDAATYYCQQWGRNPTFGGGTKLEIKRADAAPTVSIF 117
>7x3y_B L 9A3 light chain
Length=108
Score = 31.2 bits (69), Expect = 8.7, Method: Compositional matrix adjust.
Identities = 20/82 (24%), Positives = 37/82 (45%), Gaps = 21/82 (26%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR----- 80
++++ PG+ VT+TC ++ +HW +K +G+ P W +G+ R
Sbjct 10 IMSASPGEKVTMTCRASSSVSSSYLHWYQQK--SGASPKLWIYSTSNLASGVPARFSGSG 67
Query 81 ------LLLRSVQLHDSGNYSC 96
L + SV+ D+ Y C
Sbjct 68 SGTSYSLTISSVEAEDAATYYC 89
>7x4k_B L 9A3 light chain
Length=108
Score = 31.2 bits (69), Expect = 8.7, Method: Compositional matrix adjust.
Identities = 20/82 (24%), Positives = 37/82 (45%), Gaps = 21/82 (26%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR----- 80
++++ PG+ VT+TC ++ +HW +K +G+ P W +G+ R
Sbjct 10 IMSASPGEKVTMTCRASSSVSSSYLHWYQQK--SGASPKLWIYSTSNLASGVPARFSGSG 67
Query 81 ------LLLRSVQLHDSGNYSC 96
L + SV+ D+ Y C
Sbjct 68 SGTSYSLTISSVEAEDAATYYC 89
>7x3d_F L 9A3 light chain
Length=108
Score = 31.2 bits (69), Expect = 8.7, Method: Compositional matrix adjust.
Identities = 20/82 (24%), Positives = 37/82 (45%), Gaps = 21/82 (26%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR----- 80
++++ PG+ VT+TC ++ +HW +K +G+ P W +G+ R
Sbjct 10 IMSASPGEKVTMTCRASSSVSSSYLHWYQQK--SGASPKLWIYSTSNLASGVPARFSGSG 67
Query 81 ------LLLRSVQLHDSGNYSC 96
L + SV+ D+ Y C
Sbjct 68 SGTSYSLTISSVEAEDAATYYC 89
>7x3f_B L 9A3 light chain
Length=108
Score = 31.2 bits (69), Expect = 8.7, Method: Compositional matrix adjust.
Identities = 20/82 (24%), Positives = 37/82 (45%), Gaps = 21/82 (26%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR----- 80
++++ PG+ VT+TC ++ +HW +K +G+ P W +G+ R
Sbjct 10 IMSASPGEKVTMTCRASSSVSSSYLHWYQQK--SGASPKLWIYSTSNLASGVPARFSGSG 67
Query 81 ------LLLRSVQLHDSGNYSC 96
L + SV+ D+ Y C
Sbjct 68 SGTSYSLTISSVEAEDAATYYC 89
>7x3e_F L 9A3 light chain
Length=108
Score = 31.2 bits (69), Expect = 8.7, Method: Compositional matrix adjust.
Identities = 20/82 (24%), Positives = 37/82 (45%), Gaps = 21/82 (26%)
Query 34 VLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR----- 80
++++ PG+ VT+TC ++ +HW +K +G+ P W +G+ R
Sbjct 10 IMSASPGEKVTMTCRASSSVSSSYLHWYQQK--SGASPKLWIYSTSNLASGVPARFSGSG 67
Query 81 ------LLLRSVQLHDSGNYSC 96
L + SV+ D+ Y C
Sbjct 68 SGTSYSLTISSVEAEDAATYYC 89
>1pgr_B B PROTEIN (G-CSF RECEPTOR)
Length=215
Score = 32.3 bits (72), Expect = 8.8, Method: Compositional matrix adjust.
Identities = 48/210 (23%), Positives = 80/210 (38%), Gaps = 22/210 (10%)
Query 113 PPEEP-QLSCFRKSPLSNVVCEWGPRSTPSLTTKAVLLVRKFQNSPAEDFQEPCQYSQES 171
PP P LSC +++VC+W P L T +L + F++ +Q +
Sbjct 4 PPASPSNLSCLMHLTTNSLVCQWEPGPETHLPTSFIL--KSFRSRADCQYQGDTIPDCVA 61
Query 172 QKFSCQLAVPEGDSSFY---IVSMCVASSVGSKFSKTQTFQGCGILQPDPPA----NITV 224
+K ++P + Y + + + +GS S + + +PP +I
Sbjct 62 KKRQNNCSIPRKNLLLYQYMAIWVQAENMLGSSESPKLCLDPMDVXKLEPPMLQALDIGP 121
Query 225 TAVARNPRWLSVTWQDPHSWN-SSFYRLRFELRYR-----AERSKTFTTWMVKDLQHHCV 278
P L ++W+ W S + ELRY+ A + F KD C
Sbjct 122 DXXXXQPGCLWLSWK---PWKPSEYMEQECELRYQPQLKGANWTLVFHLPSSKDQFELCG 178
Query 279 IHDAWSGLRHVVQLRAQEEFGQGEWSEWSP 308
+H A + +Q+R G WS WSP
Sbjct 179 LHQA---PVYTLQMRCIRSSLPGFWSPWSP 205
>8ghp_C L anti-GUCY2C-scFv antibody light chain
Length=119
Score = 31.2 bits (69), Expect = 8.8, Method: Compositional matrix adjust.
Identities = 24/82 (29%), Positives = 35/82 (43%), Gaps = 20/82 (24%)
Query 35 LTSLPGDSVTLTCPGVEPED---NATVHWVLRKPA-------------AGSHPSRWAGMG 78
L++ GD VT+TC E D ++ + W +KP A PSR++G G
Sbjct 11 LSASVGDRVTITCRASESVDYYGSSLLQWYQQKPGKAPKLLIYAASKLASGVPSRFSGSG 70
Query 79 R----RLLLRSVQLHDSGNYSC 96
L + S+Q D Y C
Sbjct 71 SGTDFTLTISSLQPEDFATYYC 92
>6m87_F I Fab 10A6 light chain
Length=215
Score = 32.3 bits (72), Expect = 9.3, Method: Compositional matrix adjust.
Identities = 21/85 (25%), Positives = 39/85 (46%), Gaps = 23/85 (27%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ PG+ VT+TC + VHW +K +G+ P RW +G+ R
Sbjct 9 AIMSASPGEKVTMTCSA--SSSVSYVHWYQQK--SGTSPKRWIYDTSKLASGVPARFSGS 64
Query 81 -------LLLRSVQLHDSGNYSCYR 98
L + S++ D+ Y C++
Sbjct 65 GSGTSYSLTISSMEAEDAATYYCHQ 89
>1gl4_B B BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE PROTEIN
Length=98
Score = 30.8 bits (68), Expect = 9.4, Method: Compositional matrix adjust.
Identities = 19/58 (33%), Positives = 24/58 (41%), Gaps = 2/58 (3%)
Query 39 PGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSC 96
PG VT C T+ W + G PSR L +R+VQ D+G Y C
Sbjct 24 PGADVTFICTAKSKSPAYTLVWT--RLHNGKLPSRAMDFNGILTIRNVQPSDAGTYVC 79
>6m87_E G Fab 10A6 light chain
Length=215
Score = 32.0 bits (71), Expect = 9.5, Method: Compositional matrix adjust.
Identities = 21/85 (25%), Positives = 39/85 (46%), Gaps = 23/85 (27%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ PG+ VT+TC + VHW +K +G+ P RW +G+ R
Sbjct 9 AIMSASPGEKVTMTCSA--SSSVSYVHWYQQK--SGTSPKRWIYDTSKLASGVPARFSGS 64
Query 81 -------LLLRSVQLHDSGNYSCYR 98
L + S++ D+ Y C++
Sbjct 65 GSGTSYSLTISSMEAEDAATYYCHQ 89
>6m87_C C Fab 10A6 light chain
Length=215
Score = 32.0 bits (71), Expect = 9.5, Method: Compositional matrix adjust.
Identities = 21/85 (25%), Positives = 39/85 (46%), Gaps = 23/85 (27%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ PG+ VT+TC + VHW +K +G+ P RW +G+ R
Sbjct 9 AIMSASPGEKVTMTCSA--SSSVSYVHWYQQK--SGTSPKRWIYDTSKLASGVPARFSGS 64
Query 81 -------LLLRSVQLHDSGNYSCYR 98
L + S++ D+ Y C++
Sbjct 65 GSGTSYSLTISSMEAEDAATYYCHQ 89
>6m87_G K Fab 10A6 light chain
Length=215
Score = 32.0 bits (71), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 21/85 (25%), Positives = 39/85 (46%), Gaps = 23/85 (27%)
Query 33 GVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRW--------AGMGRR---- 80
++++ PG+ VT+TC + VHW +K +G+ P RW +G+ R
Sbjct 9 AIMSASPGEKVTMTCSA--SSSVSYVHWYQQK--SGTSPKRWIYDTSKLASGVPARFSGS 64
Query 81 -------LLLRSVQLHDSGNYSCYR 98
L + S++ D+ Y C++
Sbjct 65 GSGTSYSLTISSMEAEDAATYYCHQ 89
>7kq7_C B Interleukin-21 receptor
Length=214
Score = 32.0 bits (71), Expect = 9.9, Method: Compositional matrix adjust.
Identities = 35/132 (27%), Positives = 56/132 (42%), Gaps = 19/132 (14%)
Query 189 IVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVAR-NPRWLSVTWQDPHSWNSS 247
I S+ + G+ + +F ++P PP N+TVT + N W S ++DP +
Sbjct 74 IFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTVTFSGQYNISWRS-DYEDP-----A 127
Query 248 FYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGL---------RHVVQLRAQEEF 298
FY L+ +L+Y + W V + + L + +Q+RA
Sbjct 128 FYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMP 187
Query 299 G---QGEWSEWS 307
G QG WSEWS
Sbjct 188 GSSYQGTWSEWS 199
Lambda K H a alpha
0.317 0.132 0.417 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 47331240578
Database: unitmol_20240403.fasta
Posted date: Apr 4, 2024 8:53 PM
Number of letters in database: 237,935,689
Number of sequences in database: 829,018
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40