Contact Molecules for Homologous Proteins | ||||
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PID | QueryLength | Homolgous Sequence in PDB | UniProt Query | TITLE |
20585 | 425 | 13 | P84022(SMAD3_HUMAN) | RecName: Full=Mothers against decapentaplegic homolog 3; Short=MAD homolog 3; Short=Mad3; Short=Mothers against DPP homolog 3; Short=hMAD-3;AltName: Full=JV15-2;AltName: Full=SMAD family member 3; Short=SMAD 3; Short=Smad3; Short=hSMAD3; |
QUERYSEQ |
MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEF PPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIG GEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS |
425 |
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region | name | description |
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2-425 | CHAIN | /note="Mothers against decapentaplegic homolog 3" /id="PRO_0000090856" |
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10-136 | DOMAIN | /note="MH1" |
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232-425 | DOMAIN | /note="MH2" |
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137-231 | REGION | /note="Linker" |
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165-208 | REGION | /note="Disordered" |
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271-324 | REGION | /note="Sufficient for interaction with XPO4" |
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64-64 | BINDING | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
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109-109 | BINDING | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
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121-121 | BINDING | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
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126-126 | BINDING | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
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1-425 | DISORDER | predicted by DISOPRED |
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425 | |||||||
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pdb_id | a1 | identity[%]2 | description | |||
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A | 100.0 | SMAD3_HUMAN SMAD 3 | |||
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C | 100.0 | SMAD3_HUMAN SMAD 3 | |||
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue. |
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425 | pdb_id | contact mol | homologue | ||||
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a3 | description | a4 | identity[%]5 | Ncon6 | description | |
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B | ZFYV9_HUMAN Madh-interacting protein[38 aa] | A | 100.0 /100.0 |
31 /31 |
SMAD3_HUMAN SMAD 3 |
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B | SMAD4_HUMAN Mothers against decapentaplegic homolog 4[193 aa] | A | 96.3 /100.0 |
27 /28 |
SMAD3_HUMAN Mothers against decapentaplegic homolog 3 |
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B | SMAD4_HUMAN Mothers against decapentaplegic homolog 4[193 aa] | C | 100.0 /100.0 |
20 /20 |
SMAD3_HUMAN Mothers against decapentaplegic homolog 3 |
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B | THIO_ECOLI FOXH1_HUMAN Thioredoxin 1,Forkhead box protein H1[133 aa] | A | 100.0 /100.0 |
26 /26 |
SMAD3_HUMAN Mothers against decapentaplegic homolog 3 |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
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425 | pdb_id | contact mol | homologue | ||||
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a3 | description | a4 | identity[%]5 | Ncon6 | description | |
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A | DNA | C | 100.0 /100.0 |
9 /9 |
SMAD3_HUMAN SMAD3 |
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B | DNA | C | 100.0 /100.0 |
4 /4 |
SMAD3_HUMAN SMAD3 |
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B | DNA | D | 100.0 /100.0 |
7 /7 |
SMAD3_HUMAN SMAD3 |
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A | Smad binding element | C | 100.0 /100.0 |
10 /10 |
SMAD3_HUMAN SMAD 3 |
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B | Smad binding element | C | 100.0 /100.0 |
6 /6 |
SMAD3_HUMAN SMAD 3 |
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C | DNA (5'-D(P*TP*GP*CP*AP*GP*GP*CP*GP*CP*GP*CP*CP*TP.. | A | 100.0 /100.0 |
5 /5 |
SMAD3_HUMAN Mothers against decapentaplegic homolog 3 |
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D | DNA (5'-D(P*TP*GP*CP*AP*GP*GP*CP*GP*CP*GP*CP*CP*TP.. | A | 100.0 /100.0 |
9 /9 |
SMAD3_HUMAN Mothers against decapentaplegic homolog 3 |
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C | DNA (5'-D(P*CP*AP*GP*GP*CP*TP*AP*GP*CP*CP*TP*GP*CP.. | A | 100.0 /100.0 |
8 /8 |
SMAD3_HUMAN Mothers against decapentaplegic homolog 3 |
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D | DNA (5'-D(P*CP*AP*GP*GP*CP*TP*AP*GP*CP*CP*TP*GP*CP.. | A | 100.0 /100.0 |
5 /5 |
SMAD3_HUMAN Mothers against decapentaplegic homolog 3 |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
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425 | pdb_id | contact mol | homologue | ||||
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a3 | description | a4 | identity[%]5 | Ncon6 | description | |
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E |
ZN
|
C | 100.0 /100.0 |
4 /4 |
SMAD3_HUMAN SMAD 3 |
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E |
ZN
|
A | 100.0 /100.0 |
4 /4 |
SMAD3_HUMAN Mothers against decapentaplegic homolog 3 |
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F |
CL
|
A | 100.0 /100.0 |
1 /1 |
SMAD3_HUMAN Mothers against decapentaplegic homolog 3 |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
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425 | pdb_id | contact mol | homologue | ||||
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a3 | description | a4 | identity[%]5 | Ncon6 | description | |
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A | SMAD3_HUMAN SMAD 3[197 aa] | A | 100.0 /100.0 |
12 /12 |
SMAD3_HUMAN SMAD 3 |
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C | SMAD3_HUMAN Mothers against decapentaplegic homolog 3[196 aa] | A | 100.0 /100.0 |
23 /23 |
SMAD3_HUMAN Mothers against decapentaplegic homolog 3 |
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A | SMAD3_HUMAN Mothers against decapentaplegic homolog 3[198 aa] | C | 95.7 /100.0 |
23 /24 |
SMAD3_HUMAN Mothers against decapentaplegic homolog 3 |
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A | SMAD3_HUMAN Mothers against decapentaplegic homolog 3[194 aa] | A | 100.0 /100.0 |
17 /17 |
SMAD3_HUMAN Mothers against decapentaplegic homolog 3 |
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A | SMAD3_HUMAN Mothers against decapentaplegic homolog 3[194 aa] | A | 100.0 /100.0 |
14 /14 |
SMAD3_HUMAN Mothers against decapentaplegic homolog 3 |
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D | SMAD3_HUMAN SMAD 3[124 aa] | C | 100.0 /100.0 |
1 /1 |
SMAD3_HUMAN SMAD 3 |
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B | SMAD3_HUMAN Mothers against decapentaplegic homolog 3[126 aa] | A | 100.0 /100.0 |
5 /5 |
SMAD3_HUMAN Mothers against decapentaplegic homolog 3 |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. | |||||||
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425 | pdb_id | contact mol | homologue | ||||
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a3 | description | a4 | identity[%]5 | Ncon6 | description | |
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C |
ACY
|
A | 100.0 /100.0 |
6 /6 |
SMAD3_HUMAN SMAD 3 |
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D |
ACY
|
A | 100.0 /100.0 |
6 /6 |
SMAD3_HUMAN SMAD 3 |
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E |
ACY
|
A | 100.0 /100.0 |
3 /3 |
SMAD3_HUMAN SMAD 3 |
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F |
ACY
|
A | 100.0 /100.0 |
4 /4 |
SMAD3_HUMAN SMAD 3 |
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue. |