[Multiple Alignment(many alignments)]
[Alignment Bar(many alignments)]
[show plain BLAST file]
PSIBLAST 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Stephen F.
Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005)
"Protein database searches using compositionally adjusted
substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: uniprot_sprot.fasta
571,282 sequences; 206,678,396 total letters
Results from round 1
Query= YP_009725309.1 3'-to-5' exonuclease [Severe acute respiratory
syndrome coronavirus 2]
Length=527
Score E
Sequences producing significant alignments: (Bits) Value
sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute re... 1134 0.0
sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus... 1097 0.0
sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute res... 1094 0.0
sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus... 1090 0.0
sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus... 1087 0.0
sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East res... 714 0.0
sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus... 711 0.0
sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus... 707 0.0
sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus... 707 0.0
sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus... 676 0.0
sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavir... 671 0.0
sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavi... 668 0.0
sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavi... 668 0.0
sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavi... 667 0.0
sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavir... 665 0.0
sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavir... 665 0.0
sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavir... 663 0.0
sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavir... 662 0.0
sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavir... 662 0.0
sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavir... 660 0.0
sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavi... 656 0.0
sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious... 596 0.0
sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectiou... 593 0.0
sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious... 592 0.0
sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavir... 570 0.0
sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavir... 565 5e-180
sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavir... 561 9e-179
sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmi... 561 1e-178
sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus... 560 3e-178
sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemi... 560 5e-178
sp|P0C6V8|R1AB_BRV1 Replicase polyprotein 1ab OS=Breda virus 1 OX... 50.8 3e-05
sp|Q008X6|R1AB_WBV24 Replicase polyprotein 1ab OS=White bream vir... 50.1 6e-05
sp|P0C6V7|R1AB_BEV Replicase polyprotein 1ab OS=Berne virus OX=11... 47.8 3e-04
sp|Q9RL17|BVMO1_STRCO Baeyer-Villiger monooxygenase OS=Streptomyc... 33.5 5.3
sp|Q7Z7M0|MEGF8_HUMAN Multiple epidermal growth factor-like domai... 33.5 6.2
sp|Q8G500|LEU3_BIFLO 3-isopropylmalate dehydrogenase OS=Bifidobac... 33.1 6.3
sp|B3DTF8|LEU3_BIFLD 3-isopropylmalate dehydrogenase OS=Bifidobac... 33.1 6.3
sp|B7GUI8|LEU3_BIFLS 3-isopropylmalate dehydrogenase OS=Bifidobac... 33.1 6.5
sp|Q0D8D4|NADE_ORYSJ Glutamine-dependent NAD(+) synthetase OS=Ory... 33.1 9.0
sp|A2YII8|NADE_ORYSI Glutamine-dependent NAD(+) synthetase OS=Ory... 33.1 9.0
>sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 GN=rep PE=1
SV=1
Length=7096
Score = 1134 bits (2932), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 527/527 (100%), Positives = 527/527 (100%), Gaps = 0/527 (0%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 60
AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF
Sbjct 5926 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 5985
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV
Sbjct 5986 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 6045
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR
Sbjct 6046 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 6105
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF
Sbjct 6106 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 6165
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG
Sbjct 6166 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 6225
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA
Sbjct 6226 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 6285
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY
Sbjct 6286 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 6345
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG
Sbjct 6346 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 6405
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ
Sbjct 6406 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 6452
>sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus
Rp3/2004 OX=349344 GN=rep PE=3 SV=1
Length=7071
Score = 1097 bits (2837), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 503/527 (95%), Positives = 521/527 (99%), Gaps = 0/527 (0%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 60
AENVTGLFKDCSK+ITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF
Sbjct 5901 AENVTGLFKDCSKIITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 5960
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVA+
Sbjct 5961 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAI 6020
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
PTGYVDT NNT+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDR
Sbjct 6021 PTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDR 6080
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
VVFVLWAHGFELTSMKYFVKIGPERTCCLCD+RATCFST+SDTYACW+HS+GFDYVYNPF
Sbjct 6081 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPF 6140
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
MIDVQQWGFTGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIG
Sbjct 6141 MIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIG 6200
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
DELKIN+ACRKVQHMVVK+ALLADKFPVLHDIGNPKAIKCVPQA+VEWKFYDAQPCSDKA
Sbjct 6201 DELKINSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKA 6260
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
YKIEELFYSYATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLY
Sbjct 6261 YKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLY 6320
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VNKHAFHTPAFDKSAF NLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG
Sbjct 6321 VNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 6380
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GAVCRHHANEYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFTRLQ
Sbjct 6381 GAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQ 6427
>sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus OX=694009 GN=rep PE=1 SV=1
Length=7073
Score = 1094 bits (2829), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 501/527 (95%), Positives = 520/527 (99%), Gaps = 0/527 (0%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 60
AENVTGLFKDCSK+ITGLHPTQAPTHLSVD KFKTEGLCVDIPGIPKDMTYRRLISMMGF
Sbjct 5903 AENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGF 5962
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVAV
Sbjct 5963 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAV 6022
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
PTGYVDT NNT+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDR
Sbjct 6023 PTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDR 6082
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
VVFVLWAHGFELTSMKYFVKIGPERTCCLCD+RATCFST+SDTYACW+HS+GFDYVYNPF
Sbjct 6083 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPF 6142
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
MIDVQQWGFTGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIG
Sbjct 6143 MIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIG 6202
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
DEL++N+ACRKVQHMVVK+ALLADKFPVLHDIGNPKAIKCVPQA+VEWKFYDAQPCSDKA
Sbjct 6203 DELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKA 6262
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
YKIEELFYSYATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLY
Sbjct 6263 YKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLY 6322
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VNKHAFHTPAFDKSAF NLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG
Sbjct 6323 VNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 6382
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GAVCRHHANEYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFTRLQ
Sbjct 6383 GAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQ 6429
>sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus
279/2005 OX=389167 GN=rep PE=3 SV=1
Length=7079
Score = 1090 bits (2818), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 502/527 (95%), Positives = 518/527 (98%), Gaps = 0/527 (0%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 60
AENVTGLFKDCSK+ITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF
Sbjct 5909 AENVTGLFKDCSKIITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 5968
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVAV
Sbjct 5969 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAV 6028
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
PTGYVDT NNT+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDR
Sbjct 6029 PTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDR 6088
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFST+SDTYACW+HS+GFDYVYNPF
Sbjct 6089 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTSSDTYACWNHSVGFDYVYNPF 6148
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
MIDVQQWGFTGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIG
Sbjct 6149 MIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIG 6208
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
DELKINAACRKVQHMVVK+ALLADKF VLHDIGNPKAIKCVPQA+V+WKFYDAQPCSDKA
Sbjct 6209 DELKINAACRKVQHMVVKSALLADKFSVLHDIGNPKAIKCVPQAEVDWKFYDAQPCSDKA 6268
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
YKIEELFYSYATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLY
Sbjct 6269 YKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLY 6328
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VNKHAFHTPAFDKSAF LKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG
Sbjct 6329 VNKHAFHTPAFDKSAFTYLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 6388
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GAVCR HANEYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFTRLQ
Sbjct 6389 GAVCRRHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQ 6435
>sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus
HKU3 OX=442736 GN=rep PE=3 SV=1
Length=7067
Score = 1087 bits (2812), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 499/527 (95%), Positives = 520/527 (99%), Gaps = 0/527 (0%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 60
AENVTGLFKDCSK+ITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF
Sbjct 5897 AENVTGLFKDCSKIITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 5956
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVAV
Sbjct 5957 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAV 6016
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
PTGYVDT N+T+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDR
Sbjct 6017 PTGYVDTENSTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDR 6076
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
VVFVLWAHGFELTSMKYFVKIGPERTCCLCD+RATCFST+SDTYACW+HS+GFDYVYNPF
Sbjct 6077 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPF 6136
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
MIDVQQWGFTGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIG
Sbjct 6137 MIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIG 6196
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
DELKINAACRKVQHMVVK+ALLADKF VLHDIGNPKAI+CVPQA+V+WKFYDAQPCSDKA
Sbjct 6197 DELKINAACRKVQHMVVKSALLADKFTVLHDIGNPKAIRCVPQAEVDWKFYDAQPCSDKA 6256
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
YKIEELFYSYATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLY
Sbjct 6257 YKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLY 6316
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VNKHAFHTPAFDKSAF +LKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG
Sbjct 6317 VNKHAFHTPAFDKSAFTHLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 6376
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GAVCRHHANEYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFT+LQ
Sbjct 6377 GAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTKLQ 6423
>sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East
respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=rep PE=1 SV=1
Length=7078
Score = 714 bits (1844), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 332/529 (63%), Positives = 407/529 (77%), Gaps = 7/529 (1%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMG 59
++ VTGLFKDCS+ +GL P APT++SVD K+KT + LCV++ +P ++ Y R+IS MG
Sbjct 5909 SQIVTGLFKDCSRETSGLSPAYAPTYVSVDDKYKTSDELCVNL-NLPANVPYSRVISRMG 5967
Query 60 FKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVA 119
FK++ V GYP +FITREEA+R VR+WIGFDVEG HA+R A GTN+PLQLGFSTGVN V
Sbjct 5968 FKLDATVPGYPKLFITREEAVRQVRSWIGFDVEGAHASRNACGTNVPLQLGFSTGVNFVV 6027
Query 120 VPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSD 179
P G VDT + ++A+PPPG+QFKHL+PLM+KG W +VR +IVQMLSDTL LSD
Sbjct 6028 QPVGVVDTEWGNMLTGIAARPPPGEQFKHLVPLMHKGAAWPIVRRRIVQMLSDTLDKLSD 6087
Query 180 RVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNP 239
FV WAHGFELTS YF KIG E+ CC+C+RRA +S+ +YACW HS G+DYVYNP
Sbjct 6088 YCTFVCWAHGFELTSASYFCKIGKEQKCCMCNRRAAAYSSPLQSYACWTHSCGYDYVYNP 6147
Query 240 FMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPII 299
F +DVQQWG+ GNL +NHD YC VH AHVAS DAIMTRCLA+H CF++RVDW IEYP I
Sbjct 6148 FFVDVQQWGYVGNLATNHDRYCSVHQGAHVASNDAIMTRCLAIHSCFIERVDWDIEYPYI 6207
Query 300 GDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDK 359
E K+N+ CR V+ VV+AALLA F ++DIGNPK I V V+W ++DAQP +
Sbjct 6208 SHEKKLNSCCRIVERNVVRAALLAGSFDKVYDIGNPKGIPIVDDPVVDWHYFDAQPLTR- 6266
Query 360 AYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSL 419
K+++LFY+ S +F DG+CLFWNCNV +YP N+IVCRFDTRV S NLPGCDGGSL
Sbjct 6267 --KVQQLFYTEDMAS-RFADGLCLFWNCNVPKYPNNAIVCRFDTRVHSEFNLPGCDGGSL 6323
Query 420 YVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGK-QVVSDIDYVPLKSATCITRCN 478
YVNKHAFHTPA+D SAF +LK LPFFYYS +PCE HG ++ DIDYVPLKSA CIT CN
Sbjct 6324 YVNKHAFHTPAYDVSAFRDLKPLPFFYYSTTPCEVHGNGSMIEDIDYVPLKSAVCITACN 6383
Query 479 LGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
LGGAVCR HA EYR Y++AYN++ ++GF LW YK FD YNLW+TFT++Q
Sbjct 6384 LGGAVCRKHATEYREYMEAYNLVSASGFRLWCYKTFDIYNLWSTFTKVQ 6432
>sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus
HKU5 OX=694008 GN=rep PE=3 SV=1
Length=7182
Score = 711 bits (1835), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 328/529 (62%), Positives = 409/529 (77%), Gaps = 7/529 (1%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMG 59
++ VTGL+KDCS+ +GLHP APT++SVD K+KT + LCV++ +P ++ Y R+IS MG
Sbjct 6000 SQIVTGLYKDCSRESSGLHPAYAPTYVSVDDKYKTSDELCVNL-NVPANVPYSRVISRMG 6058
Query 60 FKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVA 119
FK++ + YP +FITR+EAIR VR+WIGFDVEG HA+R A GTN+PLQLGFSTGVN V
Sbjct 6059 FKLDASIPNYPKLFITRDEAIRQVRSWIGFDVEGAHASRNACGTNVPLQLGFSTGVNFVV 6118
Query 120 VPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSD 179
P G VDT + + ++A+PPPG+QFKHL+PLM KG W +VR +IVQMLSDTL LSD
Sbjct 6119 QPVGVVDTEWGSMLTSIAARPPPGEQFKHLVPLMNKGAAWPIVRRRIVQMLSDTLDKLSD 6178
Query 180 RVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNP 239
FV WAHGFELTS YF KIG E+ CC+C+RRA+ +S+ +YACW HS G+DYVYNP
Sbjct 6179 YCTFVCWAHGFELTSASYFCKIGKEQRCCMCNRRASTYSSPLHSYACWSHSSGYDYVYNP 6238
Query 240 FMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPII 299
F +DVQQWG+ GNL +NHD YC VH AHVAS DA+MTRCLA+H+CF++RV+W I YP I
Sbjct 6239 FFVDVQQWGYIGNLATNHDRYCSVHQGAHVASNDAVMTRCLAIHDCFIERVEWDITYPYI 6298
Query 300 GDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDK 359
E ++N+ CR V+ VV+AALLA +F ++DIGNPK I V V+W +YDAQP S
Sbjct 6299 SHEKRLNSCCRAVERNVVRAALLAGRFERVYDIGNPKGIPIVDDPVVDWHYYDAQPLSK- 6357
Query 360 AYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSL 419
K+++LFY+ + F+DG+CLFWNCNV RYP N+IVCRFDTRV S NLPGCDGGSL
Sbjct 6358 --KVQQLFYT-EDCAKNFSDGLCLFWNCNVPRYPNNAIVCRFDTRVHSEFNLPGCDGGSL 6414
Query 420 YVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGK-QVVSDIDYVPLKSATCITRCN 478
YVNKHAFHTPA+D SAF +LK LPFFYYS +PCE HG ++ DIDYVPLKSA CIT CN
Sbjct 6415 YVNKHAFHTPAYDASAFRDLKPLPFFYYSTTPCEVHGNGNMLEDIDYVPLKSAVCITACN 6474
Query 479 LGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
LGGAVCR HA EYR Y++AYN++ ++GF LW YK FD YNLW+TFT++Q
Sbjct 6475 LGGAVCRKHAAEYRDYMEAYNLVSASGFRLWCYKTFDVYNLWSTFTKIQ 6523
>sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus
133/2005 OX=389230 GN=rep PE=3 SV=1
Length=7126
Score = 707 bits (1826), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 329/529 (62%), Positives = 410/529 (78%), Gaps = 8/529 (2%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMG 59
++ VTGLFKDCS+ GL P APT+LSVD K+KT + LCV++ I ++TY R+IS MG
Sbjct 5960 SQIVTGLFKDCSREDVGLPPAYAPTYLSVDAKYKTTDELCVNL-NITPNVTYSRVISRMG 6018
Query 60 FKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVA 119
FK++ + GYP +FITR+EAIR VR+WIGFDVEG HA+R A GTN+PLQLGFSTGVN V
Sbjct 6019 FKLDATIPGYPKLFITRDEAIRQVRSWIGFDVEGAHASRNACGTNVPLQLGFSTGVNFVV 6078
Query 120 VPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSD 179
P G VDT + + +SA+PPPG+QFKHL+PLM KG W +VR +IVQMLSDTL LSD
Sbjct 6079 QPVGVVDTEWGSMLTTISARPPPGEQFKHLVPLMNKGATWPIVRRRIVQMLSDTLDKLSD 6138
Query 180 RVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNP 239
FV WAHGFELTS YF KIG E+ CC+C RRA+ FS+ +YACW HS G+DYVYNP
Sbjct 6139 YCTFVCWAHGFELTSASYFCKIGKEQRCCMCSRRASTFSSPLQSYACWSHSSGYDYVYNP 6198
Query 240 FMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPII 299
F +DVQQWG+ GNL +NHD YC +H AHVAS DAIMTRCLA+++CF++RVDW + YP I
Sbjct 6199 FFVDVQQWGYVGNLATNHDRYCGIHAGAHVASSDAIMTRCLAIYDCFIERVDWDVTYPYI 6258
Query 300 GDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDK 359
E K+N+ CR V+ VV++A+L+ KF ++DIGNPK I + + VEW FYDAQP S+
Sbjct 6259 SHEQKLNSCCRTVERNVVRSAVLSGKFDKIYDIGNPKGIPIISEP-VEWHFYDAQPLSN- 6316
Query 360 AYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSL 419
K+++LFY+ + +F DG+CLFWNCNV +YP+N++VCRFDTRV S NLPGC+GGSL
Sbjct 6317 --KVKKLFYTDDV-AKQFEDGLCLFWNCNVSKYPSNAVVCRFDTRVHSEFNLPGCNGGSL 6373
Query 420 YVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGK-QVVSDIDYVPLKSATCITRCN 478
YVNKHAFHTPA+D +AF +LK LPFFYYS +PCE HG ++ DIDYVPLKSA CIT CN
Sbjct 6374 YVNKHAFHTPAYDINAFRDLKPLPFFYYSTTPCEVHGSGNMLEDIDYVPLKSAVCITACN 6433
Query 479 LGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
LGGAVCR HA EYR Y++AYN++ +AGF LWVYK FD YNLW+TF ++Q
Sbjct 6434 LGGAVCRKHAAEYRDYMEAYNIVSAAGFRLWVYKTFDIYNLWSTFVKVQ 6482
>sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus
HKU4 OX=694007 GN=rep PE=1 SV=1
Length=7119
Score = 707 bits (1824), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 329/529 (62%), Positives = 410/529 (78%), Gaps = 8/529 (2%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMG 59
++ VTGLFKDCS+ TGL P APT+LSVD K+KT + LCV++ I ++TY R+IS MG
Sbjct 5953 SQIVTGLFKDCSREDTGLPPAYAPTYLSVDAKYKTTDELCVNL-NITPNVTYSRVISRMG 6011
Query 60 FKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVA 119
FK++ + GYP +FITR+EAIR VR+W+GFDVEG HA+R A GTN+PLQLGFSTGVN V
Sbjct 6012 FKLDATIPGYPKLFITRDEAIRQVRSWVGFDVEGAHASRNACGTNVPLQLGFSTGVNFVV 6071
Query 120 VPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSD 179
P G VDT + + +SA+PPPG+QFKHL+PLM KG W +VR +IVQMLSDTL LSD
Sbjct 6072 QPVGVVDTEWGSMLTTISARPPPGEQFKHLVPLMNKGATWPIVRRRIVQMLSDTLDKLSD 6131
Query 180 RVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNP 239
FV WAHGFELTS YF KIG E+ C +C RRA+ FS+ +YACW HS G+DYVYNP
Sbjct 6132 YCTFVCWAHGFELTSASYFCKIGKEQRCSMCSRRASTFSSPLQSYACWSHSSGYDYVYNP 6191
Query 240 FMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPII 299
F +DVQQWG+ GNL +NHD YC +H AHVAS DAIMTRCLA+++CF++RVDW + YP I
Sbjct 6192 FFVDVQQWGYVGNLATNHDRYCGIHAGAHVASSDAIMTRCLAIYDCFIERVDWDVTYPYI 6251
Query 300 GDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDK 359
E K+N+ CR V+ VV++A+L+ KF ++DIGNPK I + + VEW FYDAQP S+
Sbjct 6252 SHEQKLNSCCRTVERNVVRSAVLSGKFEKIYDIGNPKGIAIISEP-VEWHFYDAQPLSN- 6309
Query 360 AYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSL 419
K+++LFY+ S +F DG+CLFWNCNV +YP+N++VCRFDTRV S NLPGC+GGSL
Sbjct 6310 --KVKKLFYTDDV-SKQFEDGLCLFWNCNVSKYPSNAVVCRFDTRVHSEFNLPGCNGGSL 6366
Query 420 YVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGK-QVVSDIDYVPLKSATCITRCN 478
YVNKHAFHTPA+D +AF +LK LPFFYYS +PCE HG ++ DIDYVPLKSA CIT CN
Sbjct 6367 YVNKHAFHTPAYDINAFRDLKPLPFFYYSTTPCEVHGSGNMLEDIDYVPLKSAVCITACN 6426
Query 479 LGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
LGGAVCR HA EYR Y++AYN++ +AGF LWVYK FD YNLW+TF ++Q
Sbjct 6427 LGGAVCRKHAAEYRDYMEAYNIVSAAGFRLWVYKTFDIYNLWSTFVKVQ 6475
>sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus
HKU9 OX=694006 GN=rep PE=1 SV=1
Length=6930
Score = 676 bits (1743), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 321/534 (60%), Positives = 389/534 (73%), Gaps = 11/534 (2%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK-TEGLCVDIPGIPKDMTYRRLISMMG 59
+E GLFKDC+K L P APT +SV+ KFK E LCV M Y RLIS MG
Sbjct 5767 SEVTVGLFKDCAKA-EPLGPAYAPTFVSVNDKFKLNESLCVHFDTTELQMPYNRLISKMG 5825
Query 60 FKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVA 119
FK + + GY +FITRE+AIR VR W+GFDVEG HA +GTNLPLQ+GFSTGVN V
Sbjct 5826 FKFDLNIPGYSKLFITREQAIREVRGWVGFDVEGAHACGPNIGTNLPLQIGFSTGVNFVV 5885
Query 120 VPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSD 179
P+GY+DT + + + V +K PPGDQFKHLIPLM KG PW+VVR +IV+ML DTL +SD
Sbjct 5886 TPSGYIDTESGSRLANVVSKAPPGDQFKHLIPLMRKGEPWSVVRKRIVEMLCDTLDGVSD 5945
Query 180 RVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSI---GFDYV 236
V FV WAHGFELT++ YF K+GPER C +C RRAT FS+ Y+CW H G D+V
Sbjct 5946 TVTFVTWAHGFELTTLHYFAKVGPERKCFMCPRRATLFSSVYGAYSCWSHHRHIGGADFV 6005
Query 237 YNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEY 296
YNPF++DVQQWG+ GNLQ NHD C VH AHVASCDAIMTRCLA+H+CF V+W +EY
Sbjct 6006 YNPFLVDVQQWGYVGNLQVNHDNVCDVHKGAHVASCDAIMTRCLAIHDCFCGEVNWDVEY 6065
Query 297 PIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPC 356
PII +EL IN ACR VQ +V+KAA+ A ++DIGNPKAIK W FYD P
Sbjct 6066 PIIANELAINRACRSVQRVVLKAAVKALHIETIYDIGNPKAIKVYGVNVNNWNFYDTNPV 6125
Query 357 SDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDG 416
+ +++L Y Y H D+F DG+ +FWNCNVD YP N++VCRFDTRVLS LNL GC+G
Sbjct 6126 VE---GVKQLHYVYDVHRDQFKDGLAMFWNCNVDCYPHNALVCRFDTRVLSKLNLAGCNG 6182
Query 417 GSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESH---GKQVVSDIDYVPLKSATC 473
GSLYVN+HAFHT AF+K+AFVNLK LPFFYYSD+ CE+ VS++DYVPLKS C
Sbjct 6183 GSLYVNQHAFHTDAFNKNAFVNLKPLPFFYYSDTACENATGVSTNYVSEVDYVPLKSNVC 6242
Query 474 ITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
ITRCNLGGAVC+ HA+EYR +L++YN M+SAGF+LWV K FD +NLW+TF +LQ
Sbjct 6243 ITRCNLGGAVCKKHADEYRNFLESYNTMVSAGFTLWVDKTFDVFNLWSTFVKLQ 6296
>sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavirus
(strain 2) OX=76344 GN=rep PE=3 SV=1
Length=7124
Score = 671 bits (1732), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 304/524 (58%), Positives = 389/524 (74%), Gaps = 6/524 (1%)
Query 5 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEG-LCVDIPGIPKDMTYRRLISMMGFKMN 63
T LFKDCS+ G HP AP+ L+VD K+K G L V + +TY RLIS+MGFK++
Sbjct 5933 TNLFKDCSRSYAGYHPAHAPSFLAVDDKYKVGGDLAVCLNVADSAVTYSRLISLMGFKLD 5992
Query 64 YQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTG 123
++GY +FITR+EAIR VRAW+GFD EG HATR+++GTN PLQLGFSTG++ V TG
Sbjct 5993 LTLDGYCKLFITRDEAIRRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATG 6052
Query 124 YVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVF 183
+ F + A+ PPG+QFKHL+PLM +G W+VVRI+IVQMLSD L +L+D VV
Sbjct 6053 MFAERDGYVFKKAVARAPPGEQFKHLVPLMSRGQKWDVVRIRIVQMLSDHLVDLADSVVL 6112
Query 184 VLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMID 243
V WA FELT ++YF K+G E C +C++RATCF++ + Y CW HS DY+YNP ++D
Sbjct 6113 VTWAASFELTCLRYFAKVGKEVVCSVCNKRATCFNSRTGYYGCWRHSYSCDYLYNPLIVD 6172
Query 244 VQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDEL 303
+QQWG+TG+L SNHDL C VH AHVAS DAIMTRCLAVH+CF K V+W++EYPII +E+
Sbjct 6173 IQQWGYTGSLTSNHDLICSVHKGAHVASSDAIMTRCLAVHDCFCKSVNWSLEYPIISNEV 6232
Query 304 KINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKI 363
+N +CR +Q ++ +AA+L +++ V +DIGNPK + CV D +KFYDA P +
Sbjct 6233 SVNTSCRLLQRVMFRAAMLCNRYDVCYDIGNPKGLACVKGYD--FKFYDASPV---VKSV 6287
Query 364 EELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNK 423
++ Y Y H D+F DG+C+FWNCNVD+YPAN++VCRFDTRVL+ LNLPGC+GGSLYVNK
Sbjct 6288 KQFVYKYEAHKDQFLDGLCMFWNCNVDKYPANAVVCRFDTRVLNKLNLPGCNGGSLYVNK 6347
Query 424 HAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAV 483
HAFHT F ++AF NLK +PFFYYSD+PC +DYVPL+SATCITRCNLGGAV
Sbjct 6348 HAFHTSPFTRAAFENLKPMPFFYYSDTPCVYMEGMESKQVDYVPLRSATCITRCNLGGAV 6407
Query 484 CRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
C HA +YR YL++YN +AGF+ WVYK FD YNLWNTFTRLQ
Sbjct 6408 CLKHAEDYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTRLQ 6451
>sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=rep PE=3 SV=1
Length=7094
Score = 668 bits (1724), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 304/524 (58%), Positives = 389/524 (74%), Gaps = 6/524 (1%)
Query 5 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMN 63
T LFKDCSK +G HP AP+ L+VD K+K G GI +TY RLIS+MGFK++
Sbjct 5903 TNLFKDCSKSYSGYHPAHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGFKLD 5962
Query 64 YQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTG 123
++GY +FIT+EEA++ VRAW+GFD EG HATR+++GTN PLQLGFSTG++ V TG
Sbjct 5963 VTLDGYCKLFITKEEAVKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATG 6022
Query 124 YVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVF 183
+ F + AK PPG+QFKHLIPLM +G W+VVR +IVQM +D L +LSD VV
Sbjct 6023 LFADRDGYSFKKAVAKAPPGEQFKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDCVVL 6082
Query 184 VLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMID 243
V WA FELT ++YF K+G E +C +C +RAT +++ + Y CW HS+ DY+YNP ++D
Sbjct 6083 VTWAANFELTCLRYFAKVGREISCNVCTKRATAYNSRTGYYGCWRHSVTCDYLYNPLIVD 6142
Query 244 VQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDEL 303
+QQWG+ G+L SNHDLYC VH AHVAS DAIMTRCLAV++CF ++W +EYPII +EL
Sbjct 6143 IQQWGYIGSLSSNHDLYCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNEL 6202
Query 304 KINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKI 363
IN +CR +Q +++KAA+L +++ + +DIGNPKAI CV D ++KFYDAQP +
Sbjct 6203 SINTSCRVLQRVMLKAAMLCNRYTLCYDIGNPKAIACVK--DFDFKFYDAQPI---VKSV 6257
Query 364 EELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNK 423
+ L YS+ H D F DG+C+FWNCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLYVNK
Sbjct 6258 KTLLYSFEAHKDSFKDGLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNK 6317
Query 424 HAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAV 483
HAFHT F ++AF +LK +PFFYYSD+PC +DYVPLKSATCITRCNLGGAV
Sbjct 6318 HAFHTKPFSRAAFEHLKPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLGGAV 6377
Query 484 CRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
C HA EYR YL++YN +AGF+ WVYK FD YNLWNTFT+LQ
Sbjct 6378 CLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTKLQ 6421
>sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=rep PE=3 SV=1
Length=7094
Score = 668 bits (1723), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 304/524 (58%), Positives = 389/524 (74%), Gaps = 6/524 (1%)
Query 5 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMN 63
T LFKDCSK +G HP AP+ L+VD K+K G GI +TY RLIS+MGFK++
Sbjct 5903 TNLFKDCSKSYSGYHPAHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGFKLD 5962
Query 64 YQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTG 123
++GY +FIT+EEA++ VRAW+GFD EG HATR+++GTN PLQLGFSTG++ V TG
Sbjct 5963 VTLDGYCKLFITKEEAVKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATG 6022
Query 124 YVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVF 183
+ F + AK PPG+QFKHLIPLM +G W+VVR +IVQM +D L +LSD VV
Sbjct 6023 LFADRDGYSFKKAVAKAPPGEQFKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDCVVL 6082
Query 184 VLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMID 243
V WA FELT ++YF K+G E +C +C +RAT +++ + Y CW HS+ DY+YNP ++D
Sbjct 6083 VTWAANFELTCLRYFAKVGREISCNVCTKRATAYNSRTGYYGCWRHSVTCDYLYNPLIVD 6142
Query 244 VQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDEL 303
+QQWG+ G+L SNHDLYC VH AHVAS DAIMTRCLAV++CF ++W +EYPII +EL
Sbjct 6143 IQQWGYIGSLSSNHDLYCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNEL 6202
Query 304 KINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKI 363
IN +CR +Q +++KAA+L +++ + +DIGNPKAI CV D ++KFYDAQP +
Sbjct 6203 SINTSCRVLQRVMLKAAMLCNRYTLCYDIGNPKAIACVK--DFDFKFYDAQPI---VKSV 6257
Query 364 EELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNK 423
+ L YS+ H D F DG+C+FWNCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLYVNK
Sbjct 6258 KTLLYSFEAHKDSFKDGLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNK 6317
Query 424 HAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAV 483
HAFHT F ++AF +LK +PFFYYSD+PC +DYVPLKSATCITRCNLGGAV
Sbjct 6318 HAFHTKPFSRAAFEHLKPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLGGAV 6377
Query 484 CRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
C HA EYR YL++YN +AGF+ WVYK FD YNLWNTFT+LQ
Sbjct 6378 CLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTKLQ 6421
>sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavirus
(strain A59) OX=11142 GN=rep PE=1 SV=1
Length=7176
Score = 667 bits (1720), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 303/524 (58%), Positives = 386/524 (74%), Gaps = 6/524 (1%)
Query 5 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEG-LCVDIPGIPKDMTYRRLISMMGFKMN 63
T LFKDCS+ G HP AP+ L+VD K+K G L V + +TY RLIS+MGFK++
Sbjct 5985 TNLFKDCSRSYVGYHPAHAPSFLAVDDKYKVGGDLAVCLNVADSAVTYSRLISLMGFKLD 6044
Query 64 YQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTG 123
++GY +FITR+EAI+ VRAW+GFD EG HA R+++GTN PLQLGFSTG++ V TG
Sbjct 6045 LTLDGYCKLFITRDEAIKRVRAWVGFDAEGAHAIRDSIGTNFPLQLGFSTGIDFVVEATG 6104
Query 124 YVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVF 183
+ F + +A+ PPG+QFKHLIPLM +G W+VVRI+IVQMLSD L +L+D VV
Sbjct 6105 MFAERDGYVFKKAAARAPPGEQFKHLIPLMSRGQKWDVVRIRIVQMLSDHLVDLADSVVL 6164
Query 184 VLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMID 243
V WA FELT ++YF K+G E C +C +RATCF++ + Y CW HS DY+YNP ++D
Sbjct 6165 VTWAASFELTCLRYFAKVGREVVCSVCTKRATCFNSRTGYYGCWRHSYSCDYLYNPLIVD 6224
Query 244 VQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDEL 303
+QQWG+TG+L SNHD C VH AHVAS DAIMTRCLAVH+CF K V+W +EYPII +E+
Sbjct 6225 IQQWGYTGSLTSNHDPICSVHKGAHVASSDAIMTRCLAVHDCFCKSVNWNLEYPIISNEV 6284
Query 304 KINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKI 363
+N +CR +Q ++ +AA+L +++ V +DIGNPK + CV D +KFYDA P +
Sbjct 6285 SVNTSCRLLQRVMFRAAMLCNRYDVCYDIGNPKGLACVKGYD--FKFYDASPV---VKSV 6339
Query 364 EELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNK 423
++ Y Y H D+F DG+C+FWNCNVD+YPAN++VCRFDTRVL+ LNLPGC+GGSLYVNK
Sbjct 6340 KQFVYKYEAHKDQFLDGLCMFWNCNVDKYPANAVVCRFDTRVLNKLNLPGCNGGSLYVNK 6399
Query 424 HAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAV 483
HAFHT F ++AF NLK +PFFYYSD+PC +DYVPL+SATCITRCNLGGAV
Sbjct 6400 HAFHTSPFTRAAFENLKPMPFFYYSDTPCVYMEGMESKQVDYVPLRSATCITRCNLGGAV 6459
Query 484 CRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
C HA EYR YL++YN +AGF+ WVYK FD YNLWNTFTRLQ
Sbjct 6460 CLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTRLQ 6503
>sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=rep PE=3 SV=1
Length=7132
Score = 665 bits (1717), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 306/524 (58%), Positives = 390/524 (74%), Gaps = 6/524 (1%)
Query 5 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMN 63
T LFKDCSK G HP AP+ L+VD K+K E L V++ +TY RLIS+MGFK++
Sbjct 5941 TNLFKDCSKSCLGYHPAHAPSFLAVDDKYKVNENLAVNLNICEPVLTYSRLISLMGFKLD 6000
Query 64 YQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTG 123
++GY +FIT++EAI+ VR W+GFDVEG HATRE +GTN PLQ+GFSTGV+ V TG
Sbjct 6001 LTLDGYSKLFITKDEAIKRVRGWVGFDVEGAHATRENIGTNFPLQIGFSTGVDFVVEATG 6060
Query 124 YVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVF 183
+ F + AK PPG++FKHLIPLM KG W++VRI+IVQMLSD L +LSD VVF
Sbjct 6061 LFAERDCYTFKKTVAKAPPGEKFKHLIPLMSKGQKWDIVRIRIVQMLSDYLLDLSDSVVF 6120
Query 184 VLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMID 243
+ W+ FELT ++YF K+G E C +C RATC+++ + Y CW HS DYVYNP ++D
Sbjct 6121 ITWSASFELTCLRYFAKLGRELNCNVCSNRATCYNSRTGYYGCWRHSYTCDYVYNPLIVD 6180
Query 244 VQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDEL 303
+QQWG+TG+L SNHD+ C VH AHVAS DAIMTRCLA+++CF K V+W +EYPII +E+
Sbjct 6181 IQQWGYTGSLTSNHDIICNVHKGAHVASADAIMTRCLAIYDCFCKSVNWNLEYPIISNEV 6240
Query 304 KINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKI 363
IN +CR +Q +++KAA+L +++ + +DIGNPK + CV D E+KFYDA P A +
Sbjct 6241 SINTSCRLLQRVMLKAAMLCNRYNLCYDIGNPKGLACVK--DYEFKFYDAFPV---AKSV 6295
Query 364 EELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNK 423
++LFY Y H D F DG+C+FWNCNVD+YP+NSIVCRFDTRVL+ LNLPGC+GGSLYVNK
Sbjct 6296 KQLFYVYDVHKDNFKDGLCMFWNCNVDKYPSNSIVCRFDTRVLNKLNLPGCNGGSLYVNK 6355
Query 424 HAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAV 483
HAFHT F ++ F NLK +PFFYYSD+PC +DYVPL+SATCITRCNLGGAV
Sbjct 6356 HAFHTNPFTRTVFENLKPMPFFYYSDTPCVYVDGLESKQVDYVPLRSATCITRCNLGGAV 6415
Query 484 CRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
C HA EY YL++YN++ +AGF+ WVYK FD YNLWNTFT LQ
Sbjct 6416 CSKHAEEYCNYLESYNIVTTAGFTFWVYKTFDFYNLWNTFTTLQ 6459
>sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=rep PE=3 SV=1
Length=7182
Score = 665 bits (1717), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 306/524 (58%), Positives = 390/524 (74%), Gaps = 6/524 (1%)
Query 5 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMN 63
T LFKDCSK G HP AP+ L+VD K+K E L V++ +TY RLIS+MGFK++
Sbjct 5991 TNLFKDCSKSCLGYHPAHAPSFLAVDDKYKVNENLAVNLNICEPVLTYSRLISLMGFKLD 6050
Query 64 YQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTG 123
++GY +FIT++EAI+ VR W+GFDVEG HATRE +GTN PLQ+GFSTGV+ V TG
Sbjct 6051 LTLDGYSKLFITKDEAIKRVRGWVGFDVEGAHATRENIGTNFPLQIGFSTGVDFVVEATG 6110
Query 124 YVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVF 183
+ F + AK PPG++FKHLIPLM KG W++VRI+IVQMLSD L +LSD VVF
Sbjct 6111 LFAERDCYTFKKTVAKAPPGEKFKHLIPLMSKGQKWDIVRIRIVQMLSDYLLDLSDSVVF 6170
Query 184 VLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMID 243
+ W+ FELT ++YF K+G E C +C RATC+++ + Y CW HS DYVYNP ++D
Sbjct 6171 ITWSASFELTCLRYFAKLGRELNCNVCSNRATCYNSRTGYYGCWRHSYTCDYVYNPLIVD 6230
Query 244 VQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDEL 303
+QQWG+TG+L SNHD+ C VH AHVAS DAIMTRCLA+++CF K V+W +EYPII +E+
Sbjct 6231 IQQWGYTGSLTSNHDIICNVHKGAHVASADAIMTRCLAIYDCFCKSVNWNLEYPIISNEV 6290
Query 304 KINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKI 363
IN +CR +Q +++KAA+L +++ + +DIGNPK + CV D E+KFYDA P A +
Sbjct 6291 SINTSCRLLQRVMLKAAMLCNRYNLCYDIGNPKGLACVK--DYEFKFYDAFPV---AKSV 6345
Query 364 EELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNK 423
++LFY Y H D F DG+C+FWNCNVD+YP+NSIVCRFDTRVL+ LNLPGC+GGSLYVNK
Sbjct 6346 KQLFYVYDVHKDNFKDGLCMFWNCNVDKYPSNSIVCRFDTRVLNKLNLPGCNGGSLYVNK 6405
Query 424 HAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAV 483
HAFHT F ++ F NLK +PFFYYSD+PC +DYVPL+SATCITRCNLGGAV
Sbjct 6406 HAFHTNPFTRTVFENLKPMPFFYYSDTPCVYVDGLESKQVDYVPLRSATCITRCNLGGAV 6465
Query 484 CRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
C HA EY YL++YN++ +AGF+ WVYK FD YNLWNTFT LQ
Sbjct 6466 CSKHAEEYCNYLESYNIVTTAGFTFWVYKNFDFYNLWNTFTTLQ 6509
>sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavirus
OC43 OX=31631 GN=rep PE=1 SV=1
Length=7095
Score = 663 bits (1711), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 302/524 (58%), Positives = 387/524 (74%), Gaps = 6/524 (1%)
Query 5 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMN 63
T LFKDCSK +G HP AP+ L+VD K+K G GI +TY RLIS+MGFK++
Sbjct 5903 TNLFKDCSKSYSGYHPAHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGFKLD 5962
Query 64 YQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTG 123
++GY +FIT+EEA++ VRAW+GFD EG HAT +++GTN PLQLGFSTG++ V TG
Sbjct 5963 VTLDGYCKLFITKEEAVKRVRAWVGFDAEGAHATLDSIGTNFPLQLGFSTGIDFVVEATG 6022
Query 124 YVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVF 183
+ F + AK PPG+QFKHLIPLM +G W+VVR +IVQM +D L +LSD VV
Sbjct 6023 LFADRDGYSFKKAVAKAPPGEQFKHLIPLMTRGHRWDVVRPRIVQMFADHLIDLSDCVVL 6082
Query 184 VLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMID 243
V WA FELT ++YF K+G E +C +C +RAT +++ + Y CW HS+ DY+YNP ++D
Sbjct 6083 VTWAANFELTCLRYFAKVGREISCNVCTKRATVYNSRTGYYGCWRHSVTCDYLYNPLIVD 6142
Query 244 VQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDEL 303
+QQWG+ G+L SNHDLYC VH AHVAS DAIMTRCLAV++CF ++W +EYPII +EL
Sbjct 6143 IQQWGYIGSLSSNHDLYCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNEL 6202
Query 304 KINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKI 363
IN +CR +Q +++KAA+L +++ + +DIGNPK I CV D ++KFYDAQP +
Sbjct 6203 SINTSCRVLQRVILKAAMLCNRYTLCYDIGNPKGIACVK--DFDFKFYDAQPI---VKSV 6257
Query 364 EELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNK 423
+ L YS+ H D F DG+C+FWNCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLYVNK
Sbjct 6258 KTLLYSFEAHKDSFKDGLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNK 6317
Query 424 HAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAV 483
HAFHT F ++AF +LK +PFFYYSD+PC +DYVPLKSATCITRCNLGGAV
Sbjct 6318 HAFHTKPFARAAFEHLKPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLGGAV 6377
Query 484 CRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
C HA EYR YL++YN +AGF+ WVYK FD YNLWNTFT+LQ
Sbjct 6378 CLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTKLQ 6421
>sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=rep PE=3 SV=1
Length=7152
Score = 662 bits (1708), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 308/524 (59%), Positives = 385/524 (73%), Gaps = 6/524 (1%)
Query 5 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMN 63
T LFKDCSK G HP AP+ LSVD K+K E L V + +TY RLIS+MGFK++
Sbjct 5961 TNLFKDCSKNFLGYHPAHAPSFLSVDDKYKVNEDLAVCLNICEPVLTYSRLISLMGFKLD 6020
Query 64 YQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTG 123
++GY FIT++EAI+ VR W+GFDVEG HATR+ +GTN PLQ+GFSTGV+ V TG
Sbjct 6021 LTLDGYSKFFITKDEAIKRVRGWVGFDVEGAHATRDNIGTNFPLQIGFSTGVDFVVEATG 6080
Query 124 YVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVF 183
+ F R AK PPGD FKHLIPLM KG W+VVRI+IVQMLSD L +LSD VVF
Sbjct 6081 LFAERDCYIFKRTVAKAPPGDNFKHLIPLMSKGQKWDVVRIRIVQMLSDYLLDLSDSVVF 6140
Query 184 VLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMID 243
+ W+ FELT ++YF K+G E C +C RATC+++ + Y CW HS DYVYNP ++D
Sbjct 6141 ITWSASFELTCLRYFAKLGRELNCDVCPNRATCYNSRTGYYGCWRHSYTCDYVYNPLIVD 6200
Query 244 VQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDEL 303
+QQWG+TG+L SNHD+ C VH AHVAS DAIMTRCLA+++CF K V+W +EYPII +E+
Sbjct 6201 IQQWGYTGSLTSNHDIICNVHKGAHVASSDAIMTRCLAIYDCFCKSVNWNLEYPIISNEV 6260
Query 304 KINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKI 363
IN +CR +Q +++KAA+L +++ + +DIGNPK I CV D E+KFYDA P +
Sbjct 6261 SINTSCRLLQRVMLKAAMLCNRYNLCYDIGNPKGIACVK--DYEFKFYDASPV---VKSV 6315
Query 364 EELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNK 423
++LFY Y H D F DG+C+FWNCNVD+YP+NSIVCRFDTRVL+ LNLPGC+GGSLYVNK
Sbjct 6316 KQLFYVYDVHKDNFKDGLCMFWNCNVDKYPSNSIVCRFDTRVLNKLNLPGCNGGSLYVNK 6375
Query 424 HAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAV 483
HAFHT F ++ F NLK +PFFYYSD+PC +DYVPL+SATCITRCNLGGAV
Sbjct 6376 HAFHTNPFTRTVFENLKPMPFFYYSDTPCVYVDGLESKQVDYVPLRSATCITRCNLGGAV 6435
Query 484 CRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
C HA +Y YL++YN+ +AGF+ WVYK FD YNLWNTFT LQ
Sbjct 6436 CSKHAEDYCKYLESYNVATTAGFTFWVYKTFDFYNLWNTFTMLQ 6479
>sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=rep PE=3 SV=1
Length=7059
Score = 662 bits (1707), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 302/524 (58%), Positives = 387/524 (74%), Gaps = 6/524 (1%)
Query 5 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMN 63
T LFKDCSK +G HP AP+ L+VD K+K G GI +TY RLIS+MGFK++
Sbjct 5903 TNLFKDCSKSYSGYHPAHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGFKLD 5962
Query 64 YQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTG 123
++GY +FIT+EEA++ VRAW+GFD EG HATR+++GTN PLQLGFSTG++ V TG
Sbjct 5963 VTLDGYCKLFITKEEAVKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATG 6022
Query 124 YVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVF 183
+ F + AK PPG+QFKHLIPLM +G W+VVR +IVQM +D L +LSD VV
Sbjct 6023 LFADRDGYSFKKAVAKAPPGEQFKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDCVVL 6082
Query 184 VLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMID 243
V WA FELT ++YF K+G E +C + +RAT +++ + Y CW HS+ DY+YNP ++D
Sbjct 6083 VTWAANFELTCLRYFAKVGREISCNVSTKRATAYNSRTGYYGCWRHSVTCDYLYNPLIVD 6142
Query 244 VQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDEL 303
+QQWG+ G+L SNHDLYC VH AHVAS DAIMTRCLAV++CF ++W +EYPII +EL
Sbjct 6143 IQQWGYIGSLSSNHDLYCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNEL 6202
Query 304 KINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKI 363
IN +CR +Q +++KAA+L +++ + +DIGNPKAI CV D ++KFYDAQP +
Sbjct 6203 SINTSCRVLQRVMLKAAMLCNRYTLCYDIGNPKAIACVK--DFDFKFYDAQPI---VKSV 6257
Query 364 EELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNK 423
+ L Y + H D F DG+C+FWNCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLYVNK
Sbjct 6258 KTLLYFFEAHKDSFKDGLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNK 6317
Query 424 HAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAV 483
HAFHT F ++AF +LK +PFFYYSD+PC +DYVPLKSATCITRCNLGGAV
Sbjct 6318 HAFHTKPFSRAAFEHLKPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLGGAV 6377
Query 484 CRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
C HA EYR YL++YN +AGF+ WVYK FD YNLWNTFT+LQ
Sbjct 6378 CLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTKLQ 6421
>sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=rep PE=3 SV=1
Length=7094
Score = 660 bits (1702), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 301/524 (57%), Positives = 386/524 (74%), Gaps = 6/524 (1%)
Query 5 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMN 63
T LFKDCSK +G HP AP+ L+VD K+K G GI +TY RL S+MGFK++
Sbjct 5903 TNLFKDCSKSYSGYHPAHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRLTSLMGFKLD 5962
Query 64 YQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTG 123
++GY +FIT+EEA++ VRAW+GFD EG HATR+++GTN PLQLGFSTG++ V TG
Sbjct 5963 VTLDGYCKLFITKEEAVKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATG 6022
Query 124 YVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVF 183
+ F + AK PPG+QFKHLIPLM +G W+VVR +IVQM +D L +LSD VV
Sbjct 6023 LFADRDGYSFKKAVAKAPPGEQFKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDCVVL 6082
Query 184 VLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMID 243
V WA FELT ++YF K+G E +C +C +RAT +++ + Y CW HS+ DY+YNP ++D
Sbjct 6083 VTWAANFELTCLRYFAKVGREISCNVCTKRATAYNSRTGYYGCWRHSVTCDYLYNPLIVD 6142
Query 244 VQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDEL 303
+QQWG+ G+L SNHDLYC VH AHVAS DAIMTRCLAV++CF ++W +EYPII +EL
Sbjct 6143 IQQWGYIGSLSSNHDLYCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNEL 6202
Query 304 KINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKI 363
IN +CR +Q +++KAA+L +++ + +DIGNPKAI CV D ++KFYDAQP +
Sbjct 6203 SINTSCRVLQRVMLKAAMLCNRYTLCYDIGNPKAIACVK--DFDFKFYDAQPI---VKSV 6257
Query 364 EELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNK 423
+ L Y + H D F DG+C+FWNCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLYVNK
Sbjct 6258 KTLLYFFEAHKDSFKDGLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNK 6317
Query 424 HAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAV 483
HAFHT F ++AF +LK +PFFYYSD+PC +DYVPLKSATCITRCNL GAV
Sbjct 6318 HAFHTKPFSRAAFEHLKPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLVGAV 6377
Query 484 CRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
C HA EYR YL++YN +AGF+ WVYK FD YNLWNTFT+LQ
Sbjct 6378 CLKHAEEYREYLNSYNTATTAGFTFWVYKTFDFYNLWNTFTKLQ 6421
>sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavirus
(strain JHM) OX=11144 GN=rep PE=1 SV=1
Length=7180
Score = 656 bits (1693), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 302/524 (58%), Positives = 385/524 (73%), Gaps = 8/524 (2%)
Query 5 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEG-LCVDIPGIPKDMTYRRLISMMGFKMN 63
T LFKDCSK G+ P L+VD K+K G L V + +TY RLIS+MGFK++
Sbjct 5991 TNLFKDCSKSYVGIPP--CAFLLAVDDKYKVSGNLAVCLNVADSAVTYSRLISLMGFKLD 6048
Query 64 YQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTG 123
++GY +FITR+EAI+ VRAW+GFD EG HATR+++GTN PLQLGFSTG++ V TG
Sbjct 6049 LTLDGYCKLFITRDEAIKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATG 6108
Query 124 YVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVF 183
+ F + +A+ PPG+QFKHL+PLM +G W+VVRI+IVQMLSD L +L+D VV
Sbjct 6109 MFAERDGYVFKKAAARAPPGEQFKHLVPLMSRGQKWDVVRIRIVQMLSDHLVDLADSVVL 6168
Query 184 VLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMID 243
V WA FELT ++YF K+G E C +C++RATCF++ + Y CW HS DY+YNP ++D
Sbjct 6169 VTWAASFELTCLRYFAKVGKEVVCSVCNKRATCFNSRTGYYGCWRHSYSCDYLYNPLIVD 6228
Query 244 VQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDEL 303
+QQWG+TG+L SNHD C VH AHVAS DAIMTRCLAVH+CF K V+W +EYPII +E+
Sbjct 6229 IQQWGYTGSLTSNHDPICSVHKGAHVASSDAIMTRCLAVHDCFCKSVNWNLEYPIISNEV 6288
Query 304 KINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKI 363
+N +CR +Q ++ +AA+L +++ V +DIGNPK + CV D +KFYDA P +
Sbjct 6289 SVNTSCRLLQRVMFRAAMLCNRYDVCYDIGNPKGLACVKGYD--FKFYDASPV---VKSV 6343
Query 364 EELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNK 423
++ Y Y H D+F DG+C+FWNCNVD+YPAN++VCRFDTRVLS LNLPGC+GGSLYVNK
Sbjct 6344 KQFVYKYEAHKDQFLDGLCMFWNCNVDKYPANAVVCRFDTRVLSKLNLPGCNGGSLYVNK 6403
Query 424 HAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAV 483
HAFHT F ++AF NLK +PFFYYSD+PC +DYVPL+SATCITRCNLGGAV
Sbjct 6404 HAFHTNPFTRAAFENLKPMPFFYYSDTPCVYMEGMESKQVDYVPLRSATCITRCNLGGAV 6463
Query 484 CRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
C HA EYR YL++YN +AGF+ WVYK FD YNLWNTFTRLQ
Sbjct 6464 CLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTRLQ 6507
>sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=rep PE=1 SV=1
Length=6631
Score = 596 bits (1536), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 277/525 (53%), Positives = 367/525 (70%), Gaps = 7/525 (1%)
Query 5 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIP--KDMTYRRLISMMGFKM 62
TGLFK C+K +G+HP A T ++ +K + + ++TY+ LIS++GFKM
Sbjct 5472 TGLFKICNKEFSGVHPAYAVTTKALAATYKVNDELAALVNVEAGSEITYKHLISLLGFKM 5531
Query 63 NYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPT 122
+ V G NMFITR+EAIR+VR W+GFDVE HA +GTNLP Q+GFSTG + V P
Sbjct 5532 SVNVEGCHNMFITRDEAIRNVRGWVGFDVEATHACGTNIGTNLPFQVGFSTGADFVVTPE 5591
Query 123 GYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVV 182
G VDT +F V++K PPG+QF HL L PW+VVR +IVQML+D L N+SD VV
Sbjct 5592 GLVDTSIGNNFEPVNSKAPPGEQFNHLRALFKSAKPWHVVRPRIVQMLADNLCNVSDCVV 5651
Query 183 FVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMI 242
FV W HG ELT+++YFVKIG ++ C C RAT F++ + YACW H +GFD+VYNP ++
Sbjct 5652 FVTWCHGLELTTLRYFVKIGKDQVCS-CGSRATTFNSHTQAYACWKHCLGFDFVYNPLLV 5710
Query 243 DVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDE 302
D+QQWG++GNLQ NHDL+C VHG+AHVAS DAIMTRCLA++ F + V+W + YP I +E
Sbjct 5711 DIQQWGYSGNLQFNHDLHCNVHGHAHVASADAIMTRCLAINNAFCQDVNWDLTYPHIANE 5770
Query 303 LKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYK 362
++N++CR +Q M + A + A K V++DIGNPK IKCV + D+ ++FYD P +
Sbjct 5771 DEVNSSCRYLQRMYLNACVDALKVNVVYDIGNPKGIKCVRRGDLNFRFYDKNPIVPNVKQ 5830
Query 363 IEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVN 422
E Y Y H DKF DG+C+FWNCNVD YP NS+VCR+DTR LS NLPGC+GGSLYVN
Sbjct 5831 FE---YDYNQHKDKFADGLCMFWNCNVDCYPDNSLVCRYDTRNLSVFNLPGCNGGSLYVN 5887
Query 423 KHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGA 482
KHAFHTP FD+++F NLK +PFF+Y SPCE+ V+ D V L + CIT+CN+GGA
Sbjct 5888 KHAFHTPKFDRTSFRNLKAMPFFFYDSSPCETIQLDGVAQ-DLVSLATKDCITKCNIGGA 5946
Query 483 VCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
VC+ HA Y ++ +YN ++AGF+ WV F+ YNLW +F+ LQ
Sbjct 5947 VCKKHAQMYADFVTSYNAAVTAGFTFWVTNNFNPYNLWKSFSALQ 5991
>sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=rep
PE=3 SV=1
Length=6629
Score = 593 bits (1528), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 276/525 (53%), Positives = 366/525 (70%), Gaps = 7/525 (1%)
Query 5 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIP--KDMTYRRLISMMGFKM 62
TGLFK C+K +G+HP A T ++ +K + + ++TY+ LIS++GFKM
Sbjct 5470 TGLFKICNKEFSGVHPAYAVTTKALAATYKVNDELAALVNVEAGSEITYKHLISLLGFKM 5529
Query 63 NYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPT 122
+ V G NMFITR+EAIR+VR W+GFDVE HA +GTNLP Q+GFSTG + V P
Sbjct 5530 SVNVEGCHNMFITRDEAIRNVRGWVGFDVEATHACGTNIGTNLPFQVGFSTGADFVVTPE 5589
Query 123 GYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVV 182
G VDT +F V++K PPG+QF HL L PW+V+R +IVQML+D L N+SD VV
Sbjct 5590 GLVDTSIGNNFEPVNSKAPPGEQFNHLRVLFKSAKPWHVIRPRIVQMLADNLCNVSDCVV 5649
Query 183 FVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMI 242
FV W HG ELT+++YFVKIG E+ C C RAT F++ + YACW H +GFD+VYNP ++
Sbjct 5650 FVTWCHGLELTTLRYFVKIGKEQVCS-CGSRATTFNSHTQAYACWKHCLGFDFVYNPLLV 5708
Query 243 DVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDE 302
D+QQWG++GNLQ NHDL+C VHG+AHVAS DAIMTRCLA++ F + V+W + YP I +E
Sbjct 5709 DIQQWGYSGNLQFNHDLHCNVHGHAHVASVDAIMTRCLAINNAFCQDVNWDLTYPHIANE 5768
Query 303 LKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYK 362
++N++CR +Q M + A + A K V++DIGNPK IKCV + DV ++FYD P +
Sbjct 5769 DEVNSSCRYLQRMYLNACVDALKVNVVYDIGNPKGIKCVRRGDVNFRFYDKNPIVRNVKQ 5828
Query 363 IEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVN 422
E Y Y H DKF DG+C+FWNCNVD YP NS+VCR+DTR LS NLPGC+GGSLYVN
Sbjct 5829 FE---YDYNQHKDKFADGLCMFWNCNVDCYPDNSLVCRYDTRNLSVFNLPGCNGGSLYVN 5885
Query 423 KHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGA 482
KHAF+TP FD+ +F NLK +PFF+Y SPCE+ V+ D V L + CIT+CN+GGA
Sbjct 5886 KHAFYTPKFDRISFRNLKAMPFFFYDSSPCETIQVDGVAQ-DLVSLATKDCITKCNIGGA 5944
Query 483 VCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
VC+ HA Y ++ +YN ++AGF+ WV + + YNLW +F+ LQ
Sbjct 5945 VCKKHAQMYAEFVTSYNAAVTAGFTFWVTNKLNPYNLWKSFSALQ 5989
>sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=rep PE=1
SV=1
Length=6629
Score = 592 bits (1527), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 276/525 (53%), Positives = 366/525 (70%), Gaps = 7/525 (1%)
Query 5 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIP--KDMTYRRLISMMGFKM 62
TGLFK C+K +G+HP A T ++ +K + + ++TY+ LIS++GFKM
Sbjct 5470 TGLFKICNKEFSGVHPAYAVTTKALAATYKVNDELAALVNVEAGSEITYKHLISLLGFKM 5529
Query 63 NYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPT 122
+ V G NMFITR+EAIR+VR W+GFDVE HA +GTNLP Q+GFSTG + V P
Sbjct 5530 SVNVEGCHNMFITRDEAIRNVRGWVGFDVEATHACGTNIGTNLPFQVGFSTGADFVVTPE 5589
Query 123 GYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVV 182
G VDT +F V++K PPG+QF HL L PW+V+R +IVQML+D L N+SD VV
Sbjct 5590 GLVDTSIGNNFEPVNSKAPPGEQFNHLRVLFKSAKPWHVIRPRIVQMLADNLCNVSDCVV 5649
Query 183 FVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMI 242
FV W HG ELT+++YFVKIG E+ C C RAT F++ + YACW H +GFD+VYNP ++
Sbjct 5650 FVTWCHGLELTTLRYFVKIGKEQVCS-CGSRATTFNSHTQAYACWKHCLGFDFVYNPLLV 5708
Query 243 DVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDE 302
D+QQWG++GNLQ NHDL+C VHG+AHVAS DAIMTRCLA++ F + V+W + YP I +E
Sbjct 5709 DIQQWGYSGNLQFNHDLHCNVHGHAHVASVDAIMTRCLAINNAFCQDVNWDLTYPHIANE 5768
Query 303 LKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYK 362
++N++CR +Q M + A + A K V++DIGNPK IKCV + DV ++FYD P +
Sbjct 5769 DEVNSSCRYLQRMYLNACVDALKVNVVYDIGNPKGIKCVRRGDVNFRFYDKNPIVRNVKQ 5828
Query 363 IEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVN 422
E Y Y H DKF DG+C+FWNCNVD YP NS+VCR+DTR LS NLPGC+GGSLYVN
Sbjct 5829 FE---YDYNQHKDKFADGLCMFWNCNVDCYPDNSLVCRYDTRNLSVFNLPGCNGGSLYVN 5885
Query 423 KHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGA 482
KHAF+TP FD+ +F NLK +PFF+Y SPCE+ V+ D V L + CIT+CN+GGA
Sbjct 5886 KHAFYTPKFDRISFRNLKAMPFFFYDSSPCETIQVDGVAQ-DLVSLATKDCITKCNIGGA 5944
Query 483 VCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
VC+ HA Y ++ +YN ++AGF+ WV + + YNLW +F+ LQ
Sbjct 5945 VCKKHAQMYAEFVTSYNAAVTAGFTFWVTNKLNPYNLWKSFSALQ 5989
>sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavirus
NL63 OX=277944 GN=rep PE=1 SV=1
Length=6729
Score = 570 bits (1469), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 285/530 (54%), Positives = 358/530 (68%), Gaps = 15/530 (3%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEG-LCVDIPGIPKDMTYRRLISMMG 59
+ V GLFK+C++ L PT A T LS+ +FKT G L V I G TY +IS MG
Sbjct 5568 SSQVCGLFKNCTRTPLNLPPTHAHTFLSLSDQFKTTGDLAVQI-GSNNVCTYEHVISFMG 5626
Query 60 FKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVA 119
F+ + + G ++F TR+ AIR+VR W+G DVE H + +GTN+PLQ+GFS GVN V
Sbjct 5627 FRFDISIPGSHSLFCTRDFAIRNVRGWLGMDVESAHVCGDNIGTNVPLQVGFSNGVNFVV 5686
Query 120 VPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSD 179
G V T V AK PPG+QF+HLIPL+ KG PW +VR +IVQM+SD L NLSD
Sbjct 5687 QTEGCVSTNFGDVIKPVCAKSPPGEQFRHLIPLLRKGQPWLIVRRRIVQMISDYLSNLSD 5746
Query 180 RVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNP 239
+VFVLWA ELT+M+YFVKIGP + C C ATC+++ S+ Y C+ H++G DYVYNP
Sbjct 5747 ILVFVLWAGSLELTTMRYFVKIGPIKY-CYCGNSATCYNSVSNEYCCFKHALGCDYVYNP 5805
Query 240 FMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPII 299
+ D+QQWG+ G+L NH +C +H N H AS DA+MTRCLAVH+CFVK VDWT+ YP I
Sbjct 5806 YAFDIQQWGYVGSLSQNHHTFCNIHRNEHDASGDAVMTRCLAVHDCFVKNVDWTVTYPFI 5865
Query 300 GDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDK 359
+E IN R VQ VV+AAL K V+HDIGNPK ++C D +W YD QP +
Sbjct 5866 ANEKFINGCGRNVQGHVVRAALKLYKPSVIHDIGNPKGVRC-AVTDAKWYCYDKQPVNS- 5923
Query 360 AYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSL 419
++ L Y YATH DG+CLFWNCNVD YP SIVCRFDTR S NL G +GGSL
Sbjct 5924 --NVKLLDYDYATHGQ--LDGLCLFWNCNVDMYPEFSIVCRFDTRTRSVFNLEGVNGGSL 5979
Query 420 YVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNL 479
YVNKHAFHTPA+DK AFV LK +PFFY+ DS C+ +QV +YVPL++++C+TRCN+
Sbjct 5980 YVNKHAFHTPAYDKRAFVKLKPMPFFYFDDSDCDVVQEQV----NYVPLRASSCVTRCNI 6035
Query 480 GGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTF--TRLQ 527
GGAVC HAN Y+ Y++AYN AGF++WV FD YNLW F T LQ
Sbjct 6036 GGAVCSKHANLYQKYVEAYNTFTQAGFNIWVPHSFDVYNLWQIFIETNLQ 6085
>sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavirus
229E OX=11137 GN=rep PE=1 SV=1
Length=6758
Score = 565 bits (1456), Expect = 5e-180, Method: Compositional matrix adjust.
Identities = 278/528 (53%), Positives = 356/528 (67%), Gaps = 13/528 (2%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEG-LCVDIPGIPKDMTYRRLISMMG 59
+E+ GLFKDC++ L P+ A T+LS+ +FKT G L V I G TY +IS MG
Sbjct 5593 SESSCGLFKDCARNPIDLPPSHATTYLSLSDRFKTSGDLAVQI-GNNNVCTYEHVISYMG 5651
Query 60 FKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVA 119
F+ + + G ++F TR+ A+RHVR W+G DVEG H T + VGTN+PLQ+GFS GV+ VA
Sbjct 5652 FRFDVSMPGSHSLFCTRDFAMRHVRGWLGMDVEGAHVTGDNVGTNVPLQVGFSNGVDFVA 5711
Query 120 VPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSD 179
P G V T + V A+ PPG+QF H++PL+ KG PW+V+R +IVQM++D L SD
Sbjct 5712 QPEGCVLTNTGSVVKPVRARAPPGEQFTHIVPLLRKGQPWSVLRKRIVQMIADFLAGSSD 5771
Query 180 RVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNP 239
+VFVLWA G ELT+M+YFVKIG + C C ATC+++ S+ Y C+ H++G DYVYNP
Sbjct 5772 VLVFVLWAGGLELTTMRYFVKIGAVKH-CQCGTVATCYNSVSNDYCCFKHALGCDYVYNP 5830
Query 240 FMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPII 299
++ID+QQWG+ G+L +NH C VH N HVAS DAIMTRCLAV++CFVK VDW+I YP+I
Sbjct 5831 YVIDIQQWGYVGSLSTNHHAICNVHRNEHVASGDAIMTRCLAVYDCFVKNVDWSITYPMI 5890
Query 300 GDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDK 359
+E IN R VQ +++AA+ +HDIGNPK I+C D +W YD P +
Sbjct 5891 ANENAINKGGRTVQSHIMRAAIKLYNPKAIHDIGNPKGIRCAV-TDAKWYCYDKNPINSN 5949
Query 360 AYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSL 419
+E Y Y TH DG+CLFWNCNVD YP SIVCRFDTR S LNL G +GGSL
Sbjct 5950 VKTLE---YDYMTHGQ--MDGLCLFWNCNVDMYPEFSIVCRFDTRTRSTLNLEGVNGGSL 6004
Query 420 YVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNL 479
YVN HAFHTPA+DK A LK PFFYY D CE QV +YVPL++ CIT+CN+
Sbjct 6005 YVNNHAFHTPAYDKRAMAKLKPAPFFYYDDGSCEVVHDQV----NYVPLRATNCITKCNI 6060
Query 480 GGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GGAVC HAN YR Y+++YN+ AGF++WV FD YNLW TFT +
Sbjct 6061 GGAVCSKHANLYRAYVESYNIFTQAGFNIWVPTTFDCYNLWQTFTEVN 6108
>sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavirus
(strain FIPV WSU-79/1146) OX=33734 GN=rep PE=1 SV=2
Length=6709
Score = 561 bits (1447), Expect = 9e-179, Method: Compositional matrix adjust.
Identities = 279/520 (54%), Positives = 353/520 (68%), Gaps = 16/520 (3%)
Query 6 GLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMNY 64
GLFKDCSK + P A T++S+ FKT +GL V+I KD+ Y +IS MGF+
Sbjct 5558 GLFKDCSKSEQYIPPAYATTYMSLSDNFKTSDGLAVNIG--TKDVKYANVISYMGFRFEA 5615
Query 65 QVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGY 124
+ GY +F TR+ A+R+VRAW+GFDVEG H + VGTN+PLQLGFS GV+ V G
Sbjct 5616 NIPGYHTLFCTRDFAMRNVRAWLGFDVEGAHVCGDNVGTNVPLQLGFSNGVDFVVQTEGC 5675
Query 125 VDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFV 184
V T V A+ PPG+QF HLIPLM KG PW++VR +IVQM+ D LSD ++FV
Sbjct 5676 VVTEKGNSIEVVKARAPPGEQFAHLIPLMRKGQPWHIVRRRIVQMVCDYFDGLSDILIFV 5735
Query 185 LWAHGFELTSMKYFVKIG-PERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMID 243
LWA G ELT+M+YFVKIG P++ C C + ATC+S++ YAC+ H++G DY+YNP+ ID
Sbjct 5736 LWAGGLELTTMRYFVKIGRPQK--CECGKSATCYSSSQCVYACFKHALGCDYLYNPYCID 5793
Query 244 VQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDEL 303
+QQWG+TG+L NH C +H N HVAS DAIMTRCLA+H+CFVKRVDW+I YP I +E
Sbjct 5794 IQQWGYTGSLSMNHHEVCNIHRNEHVASGDAIMTRCLAIHDCFVKRVDWSIVYPFIDNEE 5853
Query 304 KINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKI 363
KIN A R VQ V+KAAL +HD+GNPK I+C + W YD P ++ +
Sbjct 5854 KINKAGRIVQSHVMKAALKIFNPAAIHDVGNPKGIRCATTP-IPWFCYDRDPINNNVRCL 5912
Query 364 EELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNK 423
E Y Y H +G+ LFWNCNVD YP SIVCRFDTR S L+L GC+GG+LYVN
Sbjct 5913 E---YDYMVHGQ--MNGLMLFWNCNVDMYPEFSIVCRFDTRTRSKLSLEGCNGGALYVNN 5967
Query 424 HAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAV 483
HAFHTPA+D+ AF LK +PFFYY DS CE Q +YVPLKS CIT+CN+GGAV
Sbjct 5968 HAFHTPAYDRRAFAKLKPMPFFYYDDSNCELVDGQP----NYVPLKSNVCITKCNIGGAV 6023
Query 484 CRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTF 523
C+ HA YR Y++ YNM + AGF++W + FDTY LW+ F
Sbjct 6024 CKKHAALYRAYVEDYNMFMQAGFTIWCPQNFDTYMLWHGF 6063
>sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=rep PE=1 SV=1
Length=6684
Score = 561 bits (1446), Expect = 1e-178, Method: Compositional matrix adjust.
Identities = 278/520 (53%), Positives = 353/520 (68%), Gaps = 16/520 (3%)
Query 6 GLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMNY 64
GLFKDCSK + P A T++S+ FKT +GL V+I KD+ Y +IS MGF+
Sbjct 5533 GLFKDCSKSEQYIPPAYATTYMSLSDNFKTSDGLAVNIG--TKDVKYANVISYMGFRFEA 5590
Query 65 QVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGY 124
+ GY +F TR+ A+R+VRAW+GFDVEG H + VGTN+PLQLGFS GV+ V G
Sbjct 5591 NIPGYHTLFCTRDFAMRNVRAWLGFDVEGAHVCGDNVGTNVPLQLGFSNGVDFVVQTEGC 5650
Query 125 VDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFV 184
V T V A+ PPG+QF HLIPLM KG PW++VR +IVQM+ D LSD ++FV
Sbjct 5651 VITEKGNSIEVVKARAPPGEQFAHLIPLMRKGQPWHIVRRRIVQMVCDYFDGLSDILIFV 5710
Query 185 LWAHGFELTSMKYFVKIG-PERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMID 243
LWA G ELT+M+YFVKIG P++ C C + ATC+S++ YAC+ H++G DY+YNP+ ID
Sbjct 5711 LWAGGLELTTMRYFVKIGRPQK--CECGKSATCYSSSQSVYACFKHALGCDYLYNPYCID 5768
Query 244 VQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDEL 303
+QQWG+TG+L NH C +H N HVAS DAIMTRCLA+H+CFVKRVDW+I YP I +E
Sbjct 5769 IQQWGYTGSLSMNHHEVCNIHRNEHVASGDAIMTRCLAIHDCFVKRVDWSIVYPFIDNEE 5828
Query 304 KINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKI 363
KIN A R VQ V+KAAL +HD+GNPK I+C + W YD P ++ +
Sbjct 5829 KINKAGRIVQSHVMKAALKIFNPAAIHDVGNPKGIRCATTP-IPWFCYDRDPINN---NV 5884
Query 364 EELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNK 423
L Y Y H +G+ LFWNCNVD YP SIVCRFDTR S L+L GC+GG+LYVN
Sbjct 5885 RCLDYDYMVHGQ--MNGLMLFWNCNVDMYPEFSIVCRFDTRTRSKLSLEGCNGGALYVNN 5942
Query 424 HAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAV 483
HAFHTPA+D+ AF LK +PFFYY DS CE V +YVPLKS CIT+CN+GGAV
Sbjct 5943 HAFHTPAYDRRAFAKLKPMPFFYYDDSNCE----LVDGQPNYVPLKSNVCITKCNIGGAV 5998
Query 484 CRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTF 523
C+ HA YR Y++ YN+ + AGF++W + FDTY LW+ F
Sbjct 5999 CKKHAALYRAYVEDYNIFMQAGFTIWCPQNFDTYMLWHGF 6038
>sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus
512/2005 OX=693999 GN=rep PE=3 SV=1
Length=6793
Score = 560 bits (1443), Expect = 3e-178, Method: Compositional matrix adjust.
Identities = 272/519 (52%), Positives = 349/519 (67%), Gaps = 13/519 (3%)
Query 6 GLFKDCSKVITGLHPTQAPTHLSVDTKFKTE-GLCVDIPGIPKDMTYRRLISMMGFKMNY 64
GLFKDC K L P+ APT +S+ FKT+ L V I G+ + Y +IS MGF+ +
Sbjct 5641 GLFKDCYKGEDNLPPSHAPTFMSLSDNFKTDKDLAVQI-GVNGPVKYEHVISFMGFRFDI 5699
Query 65 QVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGY 124
V +F TR+ A+R+ R W+GFDVEG H VGTN+PLQLGFS GV+ V P G
Sbjct 5700 NVPNQHTLFCTRDFAMRNARGWLGFDVEGAHVIGSNVGTNVPLQLGFSNGVDFVVRPEGC 5759
Query 125 VDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFV 184
V T V A+ PPGDQF HL+PL+ KG PW+V+R +IVQM SD L NLSD ++FV
Sbjct 5760 VSTEVGDVIQPVRARAPPGDQFTHLLPLLRKGQPWSVIRRRIVQMCSDYLANLSDTLIFV 5819
Query 185 LWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDV 244
LW+ G ELT+M+YFVK+GP +T C C +RATC+++ + T++C+ H++G DY+YN + ID+
Sbjct 5820 LWSGGLELTTMRYFVKLGPVQT-CDCGKRATCYNSTNHTFSCFRHALGSDYIYNCYCIDI 5878
Query 245 QQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELK 304
QQWG+TG+L NH C +H N HVAS DA MTRCLA+H+CFVK VDW+I YP I +E
Sbjct 5879 QQWGYTGSLSMNHHEVCNIHRNEHVASGDAAMTRCLAIHDCFVKNVDWSITYPFIANEQA 5938
Query 305 INAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIE 364
IN + R VQ V++A L +HD+GNPK I+CV D W YD P + +E
Sbjct 5939 INKSGRLVQSHVMRAVLKLYNPKAIHDVGNPKGIRCVV-TDASWYCYDKNPTNTNVKMLE 5997
Query 365 ELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKH 424
Y Y TH DG+CLFWNCNVD YP S+VCRFDTR+ S LNL GC+GGSLYVN H
Sbjct 5998 ---YDYITHGQ--LDGLCLFWNCNVDMYPEFSVVCRFDTRMRSTLNLEGCNGGSLYVNNH 6052
Query 425 AFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVC 484
AFHTPA+DK AF LK +PFF+Y DS CE ++ ++YVPL+++ CITRCN+GGAVC
Sbjct 6053 AFHTPAYDKRAFAKLKAMPFFFYDDSECE----KLQDAVNYVPLRASNCITRCNVGGAVC 6108
Query 485 RHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTF 523
H Y Y+ AYN +AGF++WV FD +NLW TF
Sbjct 6109 SKHCALYHNYVMAYNTFTTAGFTIWVPNSFDMFNLWQTF 6147
>sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=rep PE=1 SV=1
Length=6781
Score = 560 bits (1442), Expect = 5e-178, Method: Compositional matrix adjust.
Identities = 270/519 (52%), Positives = 351/519 (68%), Gaps = 11/519 (2%)
Query 6 GLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQ 65
GLFKDCS+ L P+ A T +S+ FKT+ G+ + Y +IS MGF+ +
Sbjct 5630 GLFKDCSRGDDLLPPSHANTFMSLADNFKTDQYLAVQIGVNGPIKYEHVISFMGFRFDIN 5689
Query 66 VNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYV 125
+ + +F TR+ A+R+VR W+GFDVEG H VGTN+PLQLGFS GV+ V P G V
Sbjct 5690 IPNHHTLFCTRDFAMRNVRGWLGFDVEGAHVVGSNVGTNVPLQLGFSNGVDFVVRPEGCV 5749
Query 126 DTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVL 185
T + V A+ PPG+QF HL+PL+ +G PW+VVR +IVQM SD L NLSD ++FVL
Sbjct 5750 VTESGDYIKPVRARAPPGEQFAHLLPLLKRGQPWDVVRKRIVQMCSDYLANLSDILIFVL 5809
Query 186 WAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQ 245
WA G ELT+M+YFVKIGP ++ C C + ATC+++A TY C+ H++G DY+YNP+ ID+Q
Sbjct 5810 WAGGLELTTMRYFVKIGPSKS-CDCGKVATCYNSALHTYCCFKHALGCDYLYNPYCIDIQ 5868
Query 246 QWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKI 305
QWG+ G+L NH +C VH N HVAS DAIMTRCLA+H+CFVK VDW+I YP IG+E I
Sbjct 5869 QWGYKGSLSLNHHEHCNVHRNEHVASGDAIMTRCLAIHDCFVKNVDWSITYPFIGNEAVI 5928
Query 306 NAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEE 365
N + R VQ +++ L ++DIGNPK I+C D +W +D P + +E
Sbjct 5929 NKSGRIVQSHTMRSVLKLYNPKAIYDIGNPKGIRCA-VTDAKWFCFDKNPTNSNVKTLE- 5986
Query 366 LFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHA 425
Y Y TH DG+CLFWNCNVD YP S+VCRFDTR S LNL GC+GGSLYVN HA
Sbjct 5987 --YDYITHGQ--FDGLCLFWNCNVDMYPEFSVVCRFDTRCRSPLNLEGCNGGSLYVNNHA 6042
Query 426 FHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCR 485
FHTPAFDK AF LK +PFF+Y D+ C+ ++ I+YVPL+++ CIT+CN+GGAVC
Sbjct 6043 FHTPAFDKRAFAKLKPMPFFFYDDTECD----KLQDSINYVPLRASNCITKCNVGGAVCS 6098
Query 486 HHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFT 524
H Y Y++AYN SAGF++WV FDTYNLW TF+
Sbjct 6099 KHCAMYHSYVNAYNTFTSAGFTIWVPTSFDTYNLWQTFS 6137
>sp|P0C6V8|R1AB_BRV1 Replicase polyprotein 1ab OS=Breda virus
1 OX=360393 GN=rep PE=2 SV=1
Length=6733
Score = 50.8 bits (120), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 34/101 (34%), Positives = 52/101 (51%), Gaps = 7/101 (7%)
Query 183 FVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACW--HHSIGFDYVYNPF 240
F+L++ +L S+K++V+ G C C A C Y C + ++ + N
Sbjct 5953 FILYSCSNDLKSLKFYVEFGTNYFCS-CGELAICL-MRDGLYKCRNCYGNMSISKLVNCK 6010
Query 241 MIDVQQWGFTGNLQSNHDLYCQ-VHGNAHVASCDAIMTRCL 280
+DVQ+ LQ HD CQ HG++H A CDA+MT+CL
Sbjct 6011 YLDVQKERI--KLQDAHDAICQQFHGDSHEALCDAVMTKCL 6049
>sp|Q008X6|R1AB_WBV24 Replicase polyprotein 1ab OS=White bream
virus (isolate Blicca bjoerkna L./Germany/DF24/00) OX=766180
GN=rep PE=1 SV=1
Length=6872
Score = 50.1 bits (118), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 37/110 (34%), Positives = 54/110 (49%), Gaps = 8/110 (7%)
Query 179 DRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYA--CWHHS---IGF 233
+RVV+VL+ G +L ++ +G + TC C + AT ++ + C HH+
Sbjct 6074 NRVVYVLYGAGNDLRALTNLNIVG-DYTCEKCTKEATFYTIHREIVHTFCNHHAPSQFPL 6132
Query 234 DYVYNPFMIDVQQWGFTG-NLQSNHDLYC-QVHGNAHVASCDAIMTRCLA 281
N ID+Q +L + H C Q HG+AH AS D IMT CLA
Sbjct 6133 MGTINAQAIDIQHASANKQSLTNTHAEVCNQQHGDAHTASADTIMTGCLA 6182
>sp|P0C6V7|R1AB_BEV Replicase polyprotein 1ab OS=Berne virus OX=11156
GN=rep PE=1 SV=1
Length=6857
Score = 47.8 bits (112), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 35/103 (34%), Positives = 53/103 (51%), Gaps = 11/103 (11%)
Query 183 FVLWAHGFELTSMKYFVKIGPERTC--CLCDRRATCFSTASDTYACW--HHSIGFDYVYN 238
F+L++ +L S+K++V+ TC C C A C + Y C + + + N
Sbjct 6077 FILYSCSNDLKSLKFYVEFD---TCYFCSCGEMAICLMRDGN-YKCRNCYGGMLISKLVN 6132
Query 239 PFMIDVQQWGFTGNLQSNHDLYCQ-VHGNAHVASCDAIMTRCL 280
+DVQ+ LQ HD CQ HG++H A CDA+MT+CL
Sbjct 6133 CKYLDVQKERV--KLQDAHDAICQQFHGDSHEALCDAVMTKCL 6173
>sp|Q9RL17|BVMO1_STRCO Baeyer-Villiger monooxygenase OS=Streptomyces
coelicolor (strain ATCC BAA-471 / A3(2) / M145) OX=100226
GN=SCO0300 PE=1 SV=1
Length=603
Score = 33.5 bits (75), Expect = 5.3, Method: Compositional matrix adjust.
Identities = 29/93 (31%), Positives = 37/93 (40%), Gaps = 8/93 (9%)
Query 347 EWKFYDAQPCSDKAYKIEELF--YSYATHSDKFT----DGVCLFWNCNVDRYPA-NSIVC 399
EWK+ + A +I E F Y+ S T D W DR+ A +
Sbjct 132 EWKYAPGEEIRRHAMRIAETFDLYTDVLFSTAVTSLSWDDTTGEWIVETDRHDAFRATYV 191
Query 400 RFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFD 432
T VLS L LPG G + H FHT +D
Sbjct 192 ITATGVLSELKLPGIPGIERF-KGHTFHTSRWD 223
>sp|Q7Z7M0|MEGF8_HUMAN Multiple epidermal growth factor-like domains
protein 8 OS=Homo sapiens OX=9606 GN=MEGF8 PE=1 SV=2
Length=2845
Score = 33.5 bits (75), Expect = 6.2, Method: Composition-based stats.
Identities = 24/86 (28%), Positives = 34/86 (40%), Gaps = 10/86 (12%)
Query 203 PERTCCLCDRRATCFSTASDTYAC-WHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYC 261
PE LC +R TC +++ C W S +++ ++ G G S
Sbjct 943 PEECPPLCSQRLTCEDCLANSSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDS------ 996
Query 262 QVHGNAHVASCDAIMT--RCLAVHEC 285
VH SCD +T CL HEC
Sbjct 997 -VHSEPRCRSCDGFLTCHECLQSHEC 1021
>sp|Q8G500|LEU3_BIFLO 3-isopropylmalate dehydrogenase OS=Bifidobacterium
longum (strain NCC 2705) OX=206672 GN=leuB PE=3 SV=1
Length=343
Score = 33.1 bits (74), Expect = 6.3, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 28/60 (47%), Gaps = 5/60 (8%)
Query 431 FDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANE 490
FD +VNL+ + SP + G DID+V ++ T C GGAV R+ E
Sbjct 95 FDLDQYVNLRPSKLYKGVTSPLANPG-----DIDFVVVREGTEGLYCGAGGAVRRNTPQE 149
>sp|B3DTF8|LEU3_BIFLD 3-isopropylmalate dehydrogenase OS=Bifidobacterium
longum (strain DJO10A) OX=205913 GN=leuB PE=3 SV=1
Length=343
Score = 33.1 bits (74), Expect = 6.3, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 28/60 (47%), Gaps = 5/60 (8%)
Query 431 FDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANE 490
FD +VNL+ + SP + G DID+V ++ T C GGAV R+ E
Sbjct 95 FDLDQYVNLRPSKLYKGVTSPLANPG-----DIDFVVVREGTEGLYCGAGGAVRRNTPQE 149
>sp|B7GUI8|LEU3_BIFLS 3-isopropylmalate dehydrogenase OS=Bifidobacterium
longum subsp. infantis (strain ATCC 15697 / DSM 20088
/ JCM 1222 / NCTC 11817 / S12) OX=391904 GN=leuB PE=3 SV=1
Length=343
Score = 33.1 bits (74), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 28/60 (47%), Gaps = 5/60 (8%)
Query 431 FDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANE 490
FD +VNL+ + SP + G DID+V ++ T C GGAV R+ E
Sbjct 95 FDLDQYVNLRPSKLYKGVTSPLANPG-----DIDFVVVREGTEGLYCGAGGAVRRNTPQE 149
>sp|Q0D8D4|NADE_ORYSJ Glutamine-dependent NAD(+) synthetase OS=Oryza
sativa subsp. japonica OX=39947 GN=Os07g0167100 PE=3
SV=2
Length=735
Score = 33.1 bits (74), Expect = 9.0, Method: Compositional matrix adjust.
Identities = 32/112 (29%), Positives = 46/112 (41%), Gaps = 14/112 (13%)
Query 318 KAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKF 377
K AL+ + P+ DI + VP +F D S+ EELF + A D
Sbjct 134 KDALVDFQLPL--DISEVTSQDTVPFGYGFIQFLDVSLASETC---EELFTANAPRIDLA 188
Query 378 TDGVCLFWNCNVDRYPANSIVCRFDTRVLSNL---------NLPGCDGGSLY 420
+GV +F N + + + R D+ + L N GCDGG LY
Sbjct 189 LNGVEVFVNASGSHHQLRKLSLRIDSMRNATLACGGVYMYANQQGCDGGRLY 240
>sp|A2YII8|NADE_ORYSI Glutamine-dependent NAD(+) synthetase OS=Oryza
sativa subsp. indica OX=39946 GN=OsI_25032 PE=3 SV=1
Length=735
Score = 33.1 bits (74), Expect = 9.0, Method: Compositional matrix adjust.
Identities = 32/112 (29%), Positives = 46/112 (41%), Gaps = 14/112 (13%)
Query 318 KAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKF 377
K AL+ + P+ DI + VP +F D S+ EELF + A D
Sbjct 134 KDALVDFQLPL--DISEVTSQDTVPFGYGFIQFLDVSLASETC---EELFTANAPRIDLA 188
Query 378 TDGVCLFWNCNVDRYPANSIVCRFDTRVLSNL---------NLPGCDGGSLY 420
+GV +F N + + + R D+ + L N GCDGG LY
Sbjct 189 LNGVEVFVNASGSHHQLRKLSLRIDSMRNATLACGGVYMYANQQGCDGGRLY 240
Lambda K H a alpha
0.325 0.138 0.455 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 55109926840
Results from round 2
Query= YP_009725309.1 3'-to-5' exonuclease [Severe acute respiratory
syndrome coronavirus 2]
Length=527
Score E
Sequences producing significant alignments: (Bits) Value
Sequences used in model and found again:
sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus... 941 0.0
sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute re... 940 0.0
sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute res... 938 0.0
sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus... 937 0.0
sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus... 937 0.0
sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus... 905 0.0
sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East res... 898 0.0
sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus... 893 0.0
sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus... 891 0.0
sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavir... 888 0.0
sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavi... 885 0.0
sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavir... 879 0.0
sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavir... 879 0.0
sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavi... 878 0.0
sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavi... 878 0.0
sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavir... 875 0.0
sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemi... 875 0.0
sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavir... 873 0.0
sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavir... 872 0.0
sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus... 871 0.0
sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavir... 869 0.0
sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavir... 869 0.0
sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavi... 868 0.0
sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavir... 861 0.0
sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus... 861 0.0
sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavir... 860 0.0
sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmi... 858 0.0
sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious... 825 0.0
sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectiou... 814 0.0
sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious... 814 0.0
sp|Q008X6|R1AB_WBV24 Replicase polyprotein 1ab OS=White bream vir... 117 4e-26
sp|P0C6V8|R1AB_BRV1 Replicase polyprotein 1ab OS=Breda virus 1 OX... 117 4e-26
sp|P0C6V7|R1AB_BEV Replicase polyprotein 1ab OS=Berne virus OX=11... 112 2e-24
Sequences not found previously or not previously below threshold:
sp|P0C664|ZWILC_CAEBR Protein zwilch homolog OS=Caenorhabditis br... 34.2 4.0
>sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus
Rp3/2004 OX=349344 GN=rep PE=3 SV=1
Length=7071
Score = 941 bits (2433), Expect = 0.0, Method: Composition-based stats.
Identities = 503/527 (95%), Positives = 521/527 (99%), Gaps = 0/527 (0%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 60
AENVTGLFKDCSK+ITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF
Sbjct 5901 AENVTGLFKDCSKIITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 5960
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVA+
Sbjct 5961 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAI 6020
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
PTGYVDT NNT+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDR
Sbjct 6021 PTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDR 6080
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
VVFVLWAHGFELTSMKYFVKIGPERTCCLCD+RATCFST+SDTYACW+HS+GFDYVYNPF
Sbjct 6081 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPF 6140
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
MIDVQQWGFTGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIG
Sbjct 6141 MIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIG 6200
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
DELKIN+ACRKVQHMVVK+ALLADKFPVLHDIGNPKAIKCVPQA+VEWKFYDAQPCSDKA
Sbjct 6201 DELKINSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKA 6260
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
YKIEELFYSYATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLY
Sbjct 6261 YKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLY 6320
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VNKHAFHTPAFDKSAF NLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG
Sbjct 6321 VNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 6380
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GAVCRHHANEYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFTRLQ
Sbjct 6381 GAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQ 6427
>sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 GN=rep PE=1
SV=1
Length=7096
Score = 940 bits (2430), Expect = 0.0, Method: Composition-based stats.
Identities = 527/527 (100%), Positives = 527/527 (100%), Gaps = 0/527 (0%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 60
AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF
Sbjct 5926 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 5985
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV
Sbjct 5986 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 6045
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR
Sbjct 6046 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 6105
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF
Sbjct 6106 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 6165
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG
Sbjct 6166 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 6225
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA
Sbjct 6226 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 6285
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY
Sbjct 6286 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 6345
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG
Sbjct 6346 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 6405
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ
Sbjct 6406 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 6452
>sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus OX=694009 GN=rep PE=1 SV=1
Length=7073
Score = 938 bits (2424), Expect = 0.0, Method: Composition-based stats.
Identities = 501/527 (95%), Positives = 520/527 (99%), Gaps = 0/527 (0%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 60
AENVTGLFKDCSK+ITGLHPTQAPTHLSVD KFKTEGLCVDIPGIPKDMTYRRLISMMGF
Sbjct 5903 AENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGF 5962
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVAV
Sbjct 5963 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAV 6022
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
PTGYVDT NNT+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDR
Sbjct 6023 PTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDR 6082
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
VVFVLWAHGFELTSMKYFVKIGPERTCCLCD+RATCFST+SDTYACW+HS+GFDYVYNPF
Sbjct 6083 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPF 6142
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
MIDVQQWGFTGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIG
Sbjct 6143 MIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIG 6202
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
DEL++N+ACRKVQHMVVK+ALLADKFPVLHDIGNPKAIKCVPQA+VEWKFYDAQPCSDKA
Sbjct 6203 DELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKA 6262
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
YKIEELFYSYATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLY
Sbjct 6263 YKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLY 6322
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VNKHAFHTPAFDKSAF NLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG
Sbjct 6323 VNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 6382
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GAVCRHHANEYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFTRLQ
Sbjct 6383 GAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQ 6429
>sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus
HKU3 OX=442736 GN=rep PE=3 SV=1
Length=7067
Score = 937 bits (2423), Expect = 0.0, Method: Composition-based stats.
Identities = 499/527 (95%), Positives = 520/527 (99%), Gaps = 0/527 (0%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 60
AENVTGLFKDCSK+ITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF
Sbjct 5897 AENVTGLFKDCSKIITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 5956
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVAV
Sbjct 5957 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAV 6016
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
PTGYVDT N+T+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDR
Sbjct 6017 PTGYVDTENSTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDR 6076
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
VVFVLWAHGFELTSMKYFVKIGPERTCCLCD+RATCFST+SDTYACW+HS+GFDYVYNPF
Sbjct 6077 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPF 6136
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
MIDVQQWGFTGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIG
Sbjct 6137 MIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIG 6196
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
DELKINAACRKVQHMVVK+ALLADKF VLHDIGNPKAI+CVPQA+V+WKFYDAQPCSDKA
Sbjct 6197 DELKINAACRKVQHMVVKSALLADKFTVLHDIGNPKAIRCVPQAEVDWKFYDAQPCSDKA 6256
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
YKIEELFYSYATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLY
Sbjct 6257 YKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLY 6316
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VNKHAFHTPAFDKSAF +LKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG
Sbjct 6317 VNKHAFHTPAFDKSAFTHLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 6376
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GAVCRHHANEYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFT+LQ
Sbjct 6377 GAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTKLQ 6423
>sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus
279/2005 OX=389167 GN=rep PE=3 SV=1
Length=7079
Score = 937 bits (2421), Expect = 0.0, Method: Composition-based stats.
Identities = 502/527 (95%), Positives = 518/527 (98%), Gaps = 0/527 (0%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 60
AENVTGLFKDCSK+ITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF
Sbjct 5909 AENVTGLFKDCSKIITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 5968
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVAV
Sbjct 5969 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAV 6028
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
PTGYVDT NNT+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDR
Sbjct 6029 PTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDR 6088
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFST+SDTYACW+HS+GFDYVYNPF
Sbjct 6089 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTSSDTYACWNHSVGFDYVYNPF 6148
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
MIDVQQWGFTGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIG
Sbjct 6149 MIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIG 6208
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
DELKINAACRKVQHMVVK+ALLADKF VLHDIGNPKAIKCVPQA+V+WKFYDAQPCSDKA
Sbjct 6209 DELKINAACRKVQHMVVKSALLADKFSVLHDIGNPKAIKCVPQAEVDWKFYDAQPCSDKA 6268
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
YKIEELFYSYATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLY
Sbjct 6269 YKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLY 6328
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VNKHAFHTPAFDKSAF LKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG
Sbjct 6329 VNKHAFHTPAFDKSAFTYLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 6388
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GAVCR HANEYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFTRLQ
Sbjct 6389 GAVCRRHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQ 6435
>sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus
HKU5 OX=694008 GN=rep PE=3 SV=1
Length=7182
Score = 905 bits (2339), Expect = 0.0, Method: Composition-based stats.
Identities = 328/529 (62%), Positives = 409/529 (77%), Gaps = 7/529 (1%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMG 59
++ VTGL+KDCS+ +GLHP APT++SVD K+KT + LCV++ +P ++ Y R+IS MG
Sbjct 6000 SQIVTGLYKDCSRESSGLHPAYAPTYVSVDDKYKTSDELCVNL-NVPANVPYSRVISRMG 6058
Query 60 FKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVA 119
FK++ + YP +FITR+EAIR VR+WIGFDVEG HA+R A GTN+PLQLGFSTGVN V
Sbjct 6059 FKLDASIPNYPKLFITRDEAIRQVRSWIGFDVEGAHASRNACGTNVPLQLGFSTGVNFVV 6118
Query 120 VPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSD 179
P G VDT + + ++A+PPPG+QFKHL+PLM KG W +VR +IVQMLSDTL LSD
Sbjct 6119 QPVGVVDTEWGSMLTSIAARPPPGEQFKHLVPLMNKGAAWPIVRRRIVQMLSDTLDKLSD 6178
Query 180 RVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNP 239
FV WAHGFELTS YF KIG E+ CC+C+RRA+ +S+ +YACW HS G+DYVYNP
Sbjct 6179 YCTFVCWAHGFELTSASYFCKIGKEQRCCMCNRRASTYSSPLHSYACWSHSSGYDYVYNP 6238
Query 240 FMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPII 299
F +DVQQWG+ GNL +NHD YC VH AHVAS DA+MTRCLA+H+CF++RV+W I YP I
Sbjct 6239 FFVDVQQWGYIGNLATNHDRYCSVHQGAHVASNDAVMTRCLAIHDCFIERVEWDITYPYI 6298
Query 300 GDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDK 359
E ++N+ CR V+ VV+AALLA +F ++DIGNPK I V V+W +YDAQP S
Sbjct 6299 SHEKRLNSCCRAVERNVVRAALLAGRFERVYDIGNPKGIPIVDDPVVDWHYYDAQPLS-- 6356
Query 360 AYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSL 419
K+++LFY+ + F+DG+CLFWNCNV RYP N+IVCRFDTRV S NLPGCDGGSL
Sbjct 6357 -KKVQQLFYTED-CAKNFSDGLCLFWNCNVPRYPNNAIVCRFDTRVHSEFNLPGCDGGSL 6414
Query 420 YVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHG-KQVVSDIDYVPLKSATCITRCN 478
YVNKHAFHTPA+D SAF +LK LPFFYYS +PCE HG ++ DIDYVPLKSA CIT CN
Sbjct 6415 YVNKHAFHTPAYDASAFRDLKPLPFFYYSTTPCEVHGNGNMLEDIDYVPLKSAVCITACN 6474
Query 479 LGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
LGGAVCR HA EYR Y++AYN++ ++GF LW YK FD YNLW+TFT++Q
Sbjct 6475 LGGAVCRKHAAEYRDYMEAYNLVSASGFRLWCYKTFDVYNLWSTFTKIQ 6523
>sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East
respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=rep PE=1 SV=1
Length=7078
Score = 898 bits (2320), Expect = 0.0, Method: Composition-based stats.
Identities = 331/529 (63%), Positives = 407/529 (77%), Gaps = 7/529 (1%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMG 59
++ VTGLFKDCS+ +GL P APT++SVD K+KT + LCV++ +P ++ Y R+IS MG
Sbjct 5909 SQIVTGLFKDCSRETSGLSPAYAPTYVSVDDKYKTSDELCVNL-NLPANVPYSRVISRMG 5967
Query 60 FKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVA 119
FK++ V GYP +FITREEA+R VR+WIGFDVEG HA+R A GTN+PLQLGFSTGVN V
Sbjct 5968 FKLDATVPGYPKLFITREEAVRQVRSWIGFDVEGAHASRNACGTNVPLQLGFSTGVNFVV 6027
Query 120 VPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSD 179
P G VDT + ++A+PPPG+QFKHL+PLM+KG W +VR +IVQMLSDTL LSD
Sbjct 6028 QPVGVVDTEWGNMLTGIAARPPPGEQFKHLVPLMHKGAAWPIVRRRIVQMLSDTLDKLSD 6087
Query 180 RVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNP 239
FV WAHGFELTS YF KIG E+ CC+C+RRA +S+ +YACW HS G+DYVYNP
Sbjct 6088 YCTFVCWAHGFELTSASYFCKIGKEQKCCMCNRRAAAYSSPLQSYACWTHSCGYDYVYNP 6147
Query 240 FMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPII 299
F +DVQQWG+ GNL +NHD YC VH AHVAS DAIMTRCLA+H CF++RVDW IEYP I
Sbjct 6148 FFVDVQQWGYVGNLATNHDRYCSVHQGAHVASNDAIMTRCLAIHSCFIERVDWDIEYPYI 6207
Query 300 GDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDK 359
E K+N+ CR V+ VV+AALLA F ++DIGNPK I V V+W ++DAQP +
Sbjct 6208 SHEKKLNSCCRIVERNVVRAALLAGSFDKVYDIGNPKGIPIVDDPVVDWHYFDAQPLT-- 6265
Query 360 AYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSL 419
K+++LFY+ + +F DG+CLFWNCNV +YP N+IVCRFDTRV S NLPGCDGGSL
Sbjct 6266 -RKVQQLFYTEDM-ASRFADGLCLFWNCNVPKYPNNAIVCRFDTRVHSEFNLPGCDGGSL 6323
Query 420 YVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHG-KQVVSDIDYVPLKSATCITRCN 478
YVNKHAFHTPA+D SAF +LK LPFFYYS +PCE HG ++ DIDYVPLKSA CIT CN
Sbjct 6324 YVNKHAFHTPAYDVSAFRDLKPLPFFYYSTTPCEVHGNGSMIEDIDYVPLKSAVCITACN 6383
Query 479 LGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
LGGAVCR HA EYR Y++AYN++ ++GF LW YK FD YNLW+TFT++Q
Sbjct 6384 LGGAVCRKHATEYREYMEAYNLVSASGFRLWCYKTFDIYNLWSTFTKVQ 6432
>sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus
133/2005 OX=389230 GN=rep PE=3 SV=1
Length=7126
Score = 893 bits (2309), Expect = 0.0, Method: Composition-based stats.
Identities = 329/529 (62%), Positives = 408/529 (77%), Gaps = 8/529 (2%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMG 59
++ VTGLFKDCS+ GL P APT+LSVD K+KT + LCV++ I ++TY R+IS MG
Sbjct 5960 SQIVTGLFKDCSREDVGLPPAYAPTYLSVDAKYKTTDELCVNL-NITPNVTYSRVISRMG 6018
Query 60 FKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVA 119
FK++ + GYP +FITR+EAIR VR+WIGFDVEG HA+R A GTN+PLQLGFSTGVN V
Sbjct 6019 FKLDATIPGYPKLFITRDEAIRQVRSWIGFDVEGAHASRNACGTNVPLQLGFSTGVNFVV 6078
Query 120 VPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSD 179
P G VDT + + +SA+PPPG+QFKHL+PLM KG W +VR +IVQMLSDTL LSD
Sbjct 6079 QPVGVVDTEWGSMLTTISARPPPGEQFKHLVPLMNKGATWPIVRRRIVQMLSDTLDKLSD 6138
Query 180 RVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNP 239
FV WAHGFELTS YF KIG E+ CC+C RRA+ FS+ +YACW HS G+DYVYNP
Sbjct 6139 YCTFVCWAHGFELTSASYFCKIGKEQRCCMCSRRASTFSSPLQSYACWSHSSGYDYVYNP 6198
Query 240 FMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPII 299
F +DVQQWG+ GNL +NHD YC +H AHVAS DAIMTRCLA+++CF++RVDW + YP I
Sbjct 6199 FFVDVQQWGYVGNLATNHDRYCGIHAGAHVASSDAIMTRCLAIYDCFIERVDWDVTYPYI 6258
Query 300 GDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDK 359
E K+N+ CR V+ VV++A+L+ KF ++DIGNPK I + + VEW FYDAQP S+
Sbjct 6259 SHEQKLNSCCRTVERNVVRSAVLSGKFDKIYDIGNPKGIPIISEP-VEWHFYDAQPLSN- 6316
Query 360 AYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSL 419
K+++LFY+ F DG+CLFWNCNV +YP+N++VCRFDTRV S NLPGC+GGSL
Sbjct 6317 --KVKKLFYTDDVAKQ-FEDGLCLFWNCNVSKYPSNAVVCRFDTRVHSEFNLPGCNGGSL 6373
Query 420 YVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHG-KQVVSDIDYVPLKSATCITRCN 478
YVNKHAFHTPA+D +AF +LK LPFFYYS +PCE HG ++ DIDYVPLKSA CIT CN
Sbjct 6374 YVNKHAFHTPAYDINAFRDLKPLPFFYYSTTPCEVHGSGNMLEDIDYVPLKSAVCITACN 6433
Query 479 LGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
LGGAVCR HA EYR Y++AYN++ +AGF LWVYK FD YNLW+TF ++Q
Sbjct 6434 LGGAVCRKHAAEYRDYMEAYNIVSAAGFRLWVYKTFDIYNLWSTFVKVQ 6482
>sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus
HKU4 OX=694007 GN=rep PE=1 SV=1
Length=7119
Score = 891 bits (2302), Expect = 0.0, Method: Composition-based stats.
Identities = 329/529 (62%), Positives = 410/529 (78%), Gaps = 8/529 (2%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMG 59
++ VTGLFKDCS+ TGL P APT+LSVD K+KT + LCV++ I ++TY R+IS MG
Sbjct 5953 SQIVTGLFKDCSREDTGLPPAYAPTYLSVDAKYKTTDELCVNL-NITPNVTYSRVISRMG 6011
Query 60 FKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVA 119
FK++ + GYP +FITR+EAIR VR+W+GFDVEG HA+R A GTN+PLQLGFSTGVN V
Sbjct 6012 FKLDATIPGYPKLFITRDEAIRQVRSWVGFDVEGAHASRNACGTNVPLQLGFSTGVNFVV 6071
Query 120 VPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSD 179
P G VDT + + +SA+PPPG+QFKHL+PLM KG W +VR +IVQMLSDTL LSD
Sbjct 6072 QPVGVVDTEWGSMLTTISARPPPGEQFKHLVPLMNKGATWPIVRRRIVQMLSDTLDKLSD 6131
Query 180 RVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNP 239
FV WAHGFELTS YF KIG E+ C +C RRA+ FS+ +YACW HS G+DYVYNP
Sbjct 6132 YCTFVCWAHGFELTSASYFCKIGKEQRCSMCSRRASTFSSPLQSYACWSHSSGYDYVYNP 6191
Query 240 FMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPII 299
F +DVQQWG+ GNL +NHD YC +H AHVAS DAIMTRCLA+++CF++RVDW + YP I
Sbjct 6192 FFVDVQQWGYVGNLATNHDRYCGIHAGAHVASSDAIMTRCLAIYDCFIERVDWDVTYPYI 6251
Query 300 GDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDK 359
E K+N+ CR V+ VV++A+L+ KF ++DIGNPK I + + VEW FYDAQP S+
Sbjct 6252 SHEQKLNSCCRTVERNVVRSAVLSGKFEKIYDIGNPKGIAIISEP-VEWHFYDAQPLSN- 6309
Query 360 AYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSL 419
K+++LFY+ S +F DG+CLFWNCNV +YP+N++VCRFDTRV S NLPGC+GGSL
Sbjct 6310 --KVKKLFYTDDV-SKQFEDGLCLFWNCNVSKYPSNAVVCRFDTRVHSEFNLPGCNGGSL 6366
Query 420 YVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHG-KQVVSDIDYVPLKSATCITRCN 478
YVNKHAFHTPA+D +AF +LK LPFFYYS +PCE HG ++ DIDYVPLKSA CIT CN
Sbjct 6367 YVNKHAFHTPAYDINAFRDLKPLPFFYYSTTPCEVHGSGNMLEDIDYVPLKSAVCITACN 6426
Query 479 LGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
LGGAVCR HA EYR Y++AYN++ +AGF LWVYK FD YNLW+TF ++Q
Sbjct 6427 LGGAVCRKHAAEYRDYMEAYNIVSAAGFRLWVYKTFDIYNLWSTFVKVQ 6475
>sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavirus
(strain 2) OX=76344 GN=rep PE=3 SV=1
Length=7124
Score = 888 bits (2294), Expect = 0.0, Method: Composition-based stats.
Identities = 304/527 (58%), Positives = 390/527 (74%), Gaps = 6/527 (1%)
Query 2 ENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEG-LCVDIPGIPKDMTYRRLISMMGF 60
+ T LFKDCS+ G HP AP+ L+VD K+K G L V + +TY RLIS+MGF
Sbjct 5930 QCTTNLFKDCSRSYAGYHPAHAPSFLAVDDKYKVGGDLAVCLNVADSAVTYSRLISLMGF 5989
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
K++ ++GY +FITR+EAIR VRAW+GFD EG HATR+++GTN PLQLGFSTG++ V
Sbjct 5990 KLDLTLDGYCKLFITRDEAIRRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVE 6049
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
TG + F + A+ PPG+QFKHL+PLM +G W+VVRI+IVQMLSD L +L+D
Sbjct 6050 ATGMFAERDGYVFKKAVARAPPGEQFKHLVPLMSRGQKWDVVRIRIVQMLSDHLVDLADS 6109
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
VV V WA FELT ++YF K+G E C +C++RATCF++ + Y CW HS DY+YNP
Sbjct 6110 VVLVTWAASFELTCLRYFAKVGKEVVCSVCNKRATCFNSRTGYYGCWRHSYSCDYLYNPL 6169
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
++D+QQWG+TG+L SNHDL C VH AHVAS DAIMTRCLAVH+CF K V+W++EYPII
Sbjct 6170 IVDIQQWGYTGSLTSNHDLICSVHKGAHVASSDAIMTRCLAVHDCFCKSVNWSLEYPIIS 6229
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
+E+ +N +CR +Q ++ +AA+L +++ V +DIGNPK + CV D +KFYDA P
Sbjct 6230 NEVSVNTSCRLLQRVMFRAAMLCNRYDVCYDIGNPKGLACVKGYD--FKFYDASPV---V 6284
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
+++ Y Y H D+F DG+C+FWNCNVD+YPAN++VCRFDTRVL+ LNLPGC+GGSLY
Sbjct 6285 KSVKQFVYKYEAHKDQFLDGLCMFWNCNVDKYPANAVVCRFDTRVLNKLNLPGCNGGSLY 6344
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VNKHAFHT F ++AF NLK +PFFYYSD+PC +DYVPL+SATCITRCNLG
Sbjct 6345 VNKHAFHTSPFTRAAFENLKPMPFFYYSDTPCVYMEGMESKQVDYVPLRSATCITRCNLG 6404
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GAVC HA +YR YL++YN +AGF+ WVYK FD YNLWNTFTRLQ
Sbjct 6405 GAVCLKHAEDYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTRLQ 6451
>sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavirus
(strain A59) OX=11142 GN=rep PE=1 SV=1
Length=7176
Score = 885 bits (2287), Expect = 0.0, Method: Composition-based stats.
Identities = 303/527 (57%), Positives = 387/527 (73%), Gaps = 6/527 (1%)
Query 2 ENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEG-LCVDIPGIPKDMTYRRLISMMGF 60
+ T LFKDCS+ G HP AP+ L+VD K+K G L V + +TY RLIS+MGF
Sbjct 5982 QCTTNLFKDCSRSYVGYHPAHAPSFLAVDDKYKVGGDLAVCLNVADSAVTYSRLISLMGF 6041
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
K++ ++GY +FITR+EAI+ VRAW+GFD EG HA R+++GTN PLQLGFSTG++ V
Sbjct 6042 KLDLTLDGYCKLFITRDEAIKRVRAWVGFDAEGAHAIRDSIGTNFPLQLGFSTGIDFVVE 6101
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
TG + F + +A+ PPG+QFKHLIPLM +G W+VVRI+IVQMLSD L +L+D
Sbjct 6102 ATGMFAERDGYVFKKAAARAPPGEQFKHLIPLMSRGQKWDVVRIRIVQMLSDHLVDLADS 6161
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
VV V WA FELT ++YF K+G E C +C +RATCF++ + Y CW HS DY+YNP
Sbjct 6162 VVLVTWAASFELTCLRYFAKVGREVVCSVCTKRATCFNSRTGYYGCWRHSYSCDYLYNPL 6221
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
++D+QQWG+TG+L SNHD C VH AHVAS DAIMTRCLAVH+CF K V+W +EYPII
Sbjct 6222 IVDIQQWGYTGSLTSNHDPICSVHKGAHVASSDAIMTRCLAVHDCFCKSVNWNLEYPIIS 6281
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
+E+ +N +CR +Q ++ +AA+L +++ V +DIGNPK + CV D +KFYDA P
Sbjct 6282 NEVSVNTSCRLLQRVMFRAAMLCNRYDVCYDIGNPKGLACVKGYD--FKFYDASPV---V 6336
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
+++ Y Y H D+F DG+C+FWNCNVD+YPAN++VCRFDTRVL+ LNLPGC+GGSLY
Sbjct 6337 KSVKQFVYKYEAHKDQFLDGLCMFWNCNVDKYPANAVVCRFDTRVLNKLNLPGCNGGSLY 6396
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VNKHAFHT F ++AF NLK +PFFYYSD+PC +DYVPL+SATCITRCNLG
Sbjct 6397 VNKHAFHTSPFTRAAFENLKPMPFFYYSDTPCVYMEGMESKQVDYVPLRSATCITRCNLG 6456
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GAVC HA EYR YL++YN +AGF+ WVYK FD YNLWNTFTRLQ
Sbjct 6457 GAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTRLQ 6503
>sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=rep PE=3 SV=1
Length=7132
Score = 879 bits (2272), Expect = 0.0, Method: Composition-based stats.
Identities = 306/525 (58%), Positives = 390/525 (74%), Gaps = 6/525 (1%)
Query 4 VTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKM 62
T LFKDCSK G HP AP+ L+VD K+K E L V++ +TY RLIS+MGFK+
Sbjct 5940 TTNLFKDCSKSCLGYHPAHAPSFLAVDDKYKVNENLAVNLNICEPVLTYSRLISLMGFKL 5999
Query 63 NYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPT 122
+ ++GY +FIT++EAI+ VR W+GFDVEG HATRE +GTN PLQ+GFSTGV+ V T
Sbjct 6000 DLTLDGYSKLFITKDEAIKRVRGWVGFDVEGAHATRENIGTNFPLQIGFSTGVDFVVEAT 6059
Query 123 GYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVV 182
G + F + AK PPG++FKHLIPLM KG W++VRI+IVQMLSD L +LSD VV
Sbjct 6060 GLFAERDCYTFKKTVAKAPPGEKFKHLIPLMSKGQKWDIVRIRIVQMLSDYLLDLSDSVV 6119
Query 183 FVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMI 242
F+ W+ FELT ++YF K+G E C +C RATC+++ + Y CW HS DYVYNP ++
Sbjct 6120 FITWSASFELTCLRYFAKLGRELNCNVCSNRATCYNSRTGYYGCWRHSYTCDYVYNPLIV 6179
Query 243 DVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDE 302
D+QQWG+TG+L SNHD+ C VH AHVAS DAIMTRCLA+++CF K V+W +EYPII +E
Sbjct 6180 DIQQWGYTGSLTSNHDIICNVHKGAHVASADAIMTRCLAIYDCFCKSVNWNLEYPIISNE 6239
Query 303 LKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYK 362
+ IN +CR +Q +++KAA+L +++ + +DIGNPK + CV D E+KFYDA P A
Sbjct 6240 VSINTSCRLLQRVMLKAAMLCNRYNLCYDIGNPKGLACVK--DYEFKFYDAFPV---AKS 6294
Query 363 IEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVN 422
+++LFY Y H D F DG+C+FWNCNVD+YP+NSIVCRFDTRVL+ LNLPGC+GGSLYVN
Sbjct 6295 VKQLFYVYDVHKDNFKDGLCMFWNCNVDKYPSNSIVCRFDTRVLNKLNLPGCNGGSLYVN 6354
Query 423 KHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGA 482
KHAFHT F ++ F NLK +PFFYYSD+PC +DYVPL+SATCITRCNLGGA
Sbjct 6355 KHAFHTNPFTRTVFENLKPMPFFYYSDTPCVYVDGLESKQVDYVPLRSATCITRCNLGGA 6414
Query 483 VCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
VC HA EY YL++YN++ +AGF+ WVYK FD YNLWNTFT LQ
Sbjct 6415 VCSKHAEEYCNYLESYNIVTTAGFTFWVYKTFDFYNLWNTFTTLQ 6459
>sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=rep PE=3 SV=1
Length=7182
Score = 879 bits (2271), Expect = 0.0, Method: Composition-based stats.
Identities = 306/525 (58%), Positives = 390/525 (74%), Gaps = 6/525 (1%)
Query 4 VTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKM 62
T LFKDCSK G HP AP+ L+VD K+K E L V++ +TY RLIS+MGFK+
Sbjct 5990 TTNLFKDCSKSCLGYHPAHAPSFLAVDDKYKVNENLAVNLNICEPVLTYSRLISLMGFKL 6049
Query 63 NYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPT 122
+ ++GY +FIT++EAI+ VR W+GFDVEG HATRE +GTN PLQ+GFSTGV+ V T
Sbjct 6050 DLTLDGYSKLFITKDEAIKRVRGWVGFDVEGAHATRENIGTNFPLQIGFSTGVDFVVEAT 6109
Query 123 GYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVV 182
G + F + AK PPG++FKHLIPLM KG W++VRI+IVQMLSD L +LSD VV
Sbjct 6110 GLFAERDCYTFKKTVAKAPPGEKFKHLIPLMSKGQKWDIVRIRIVQMLSDYLLDLSDSVV 6169
Query 183 FVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMI 242
F+ W+ FELT ++YF K+G E C +C RATC+++ + Y CW HS DYVYNP ++
Sbjct 6170 FITWSASFELTCLRYFAKLGRELNCNVCSNRATCYNSRTGYYGCWRHSYTCDYVYNPLIV 6229
Query 243 DVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDE 302
D+QQWG+TG+L SNHD+ C VH AHVAS DAIMTRCLA+++CF K V+W +EYPII +E
Sbjct 6230 DIQQWGYTGSLTSNHDIICNVHKGAHVASADAIMTRCLAIYDCFCKSVNWNLEYPIISNE 6289
Query 303 LKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYK 362
+ IN +CR +Q +++KAA+L +++ + +DIGNPK + CV D E+KFYDA P A
Sbjct 6290 VSINTSCRLLQRVMLKAAMLCNRYNLCYDIGNPKGLACVK--DYEFKFYDAFPV---AKS 6344
Query 363 IEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVN 422
+++LFY Y H D F DG+C+FWNCNVD+YP+NSIVCRFDTRVL+ LNLPGC+GGSLYVN
Sbjct 6345 VKQLFYVYDVHKDNFKDGLCMFWNCNVDKYPSNSIVCRFDTRVLNKLNLPGCNGGSLYVN 6404
Query 423 KHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGA 482
KHAFHT F ++ F NLK +PFFYYSD+PC +DYVPL+SATCITRCNLGGA
Sbjct 6405 KHAFHTNPFTRTVFENLKPMPFFYYSDTPCVYVDGLESKQVDYVPLRSATCITRCNLGGA 6464
Query 483 VCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
VC HA EY YL++YN++ +AGF+ WVYK FD YNLWNTFT LQ
Sbjct 6465 VCSKHAEEYCNYLESYNIVTTAGFTFWVYKNFDFYNLWNTFTTLQ 6509
>sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=rep PE=3 SV=1
Length=7094
Score = 878 bits (2270), Expect = 0.0, Method: Composition-based stats.
Identities = 304/527 (58%), Positives = 391/527 (74%), Gaps = 6/527 (1%)
Query 2 ENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK-TEGLCVDIPGIPKDMTYRRLISMMGF 60
+ T LFKDCSK +G HP AP+ L+VD K+K T L V + +TY RLIS+MGF
Sbjct 5900 QCSTNLFKDCSKSYSGYHPAHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGF 5959
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
K++ ++GY +FIT+EEA++ VRAW+GFD EG HATR+++GTN PLQLGFSTG++ V
Sbjct 5960 KLDVTLDGYCKLFITKEEAVKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVE 6019
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
TG + F + AK PPG+QFKHLIPLM +G W+VVR +IVQM +D L +LSD
Sbjct 6020 ATGLFADRDGYSFKKAVAKAPPGEQFKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDC 6079
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
VV V WA FELT ++YF K+G E +C +C +RAT +++ + Y CW HS+ DY+YNP
Sbjct 6080 VVLVTWAANFELTCLRYFAKVGREISCNVCTKRATAYNSRTGYYGCWRHSVTCDYLYNPL 6139
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
++D+QQWG+ G+L SNHDLYC VH AHVAS DAIMTRCLAV++CF ++W +EYPII
Sbjct 6140 IVDIQQWGYIGSLSSNHDLYCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIIS 6199
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
+EL IN +CR +Q +++KAA+L +++ + +DIGNPKAI CV D ++KFYDAQP
Sbjct 6200 NELSINTSCRVLQRVMLKAAMLCNRYTLCYDIGNPKAIACVK--DFDFKFYDAQPI---V 6254
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
++ L YS+ H D F DG+C+FWNCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLY
Sbjct 6255 KSVKTLLYSFEAHKDSFKDGLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLY 6314
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VNKHAFHT F ++AF +LK +PFFYYSD+PC +DYVPLKSATCITRCNLG
Sbjct 6315 VNKHAFHTKPFSRAAFEHLKPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLG 6374
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GAVC HA EYR YL++YN +AGF+ WVYK FD YNLWNTFT+LQ
Sbjct 6375 GAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTKLQ 6421
>sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=rep PE=3 SV=1
Length=7094
Score = 878 bits (2270), Expect = 0.0, Method: Composition-based stats.
Identities = 304/527 (58%), Positives = 391/527 (74%), Gaps = 6/527 (1%)
Query 2 ENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK-TEGLCVDIPGIPKDMTYRRLISMMGF 60
+ T LFKDCSK +G HP AP+ L+VD K+K T L V + +TY RLIS+MGF
Sbjct 5900 QCSTNLFKDCSKSYSGYHPAHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGF 5959
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
K++ ++GY +FIT+EEA++ VRAW+GFD EG HATR+++GTN PLQLGFSTG++ V
Sbjct 5960 KLDVTLDGYCKLFITKEEAVKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVE 6019
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
TG + F + AK PPG+QFKHLIPLM +G W+VVR +IVQM +D L +LSD
Sbjct 6020 ATGLFADRDGYSFKKAVAKAPPGEQFKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDC 6079
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
VV V WA FELT ++YF K+G E +C +C +RAT +++ + Y CW HS+ DY+YNP
Sbjct 6080 VVLVTWAANFELTCLRYFAKVGREISCNVCTKRATAYNSRTGYYGCWRHSVTCDYLYNPL 6139
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
++D+QQWG+ G+L SNHDLYC VH AHVAS DAIMTRCLAV++CF ++W +EYPII
Sbjct 6140 IVDIQQWGYIGSLSSNHDLYCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIIS 6199
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
+EL IN +CR +Q +++KAA+L +++ + +DIGNPKAI CV D ++KFYDAQP
Sbjct 6200 NELSINTSCRVLQRVMLKAAMLCNRYTLCYDIGNPKAIACVK--DFDFKFYDAQPI---V 6254
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
++ L YS+ H D F DG+C+FWNCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLY
Sbjct 6255 KSVKTLLYSFEAHKDSFKDGLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLY 6314
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VNKHAFHT F ++AF +LK +PFFYYSD+PC +DYVPLKSATCITRCNLG
Sbjct 6315 VNKHAFHTKPFSRAAFEHLKPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLG 6374
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GAVC HA EYR YL++YN +AGF+ WVYK FD YNLWNTFT+LQ
Sbjct 6375 GAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTKLQ 6421
>sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=rep PE=3 SV=1
Length=7152
Score = 875 bits (2261), Expect = 0.0, Method: Composition-based stats.
Identities = 308/525 (59%), Positives = 385/525 (73%), Gaps = 6/525 (1%)
Query 4 VTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKM 62
T LFKDCSK G HP AP+ LSVD K+K E L V + +TY RLIS+MGFK+
Sbjct 5960 TTNLFKDCSKNFLGYHPAHAPSFLSVDDKYKVNEDLAVCLNICEPVLTYSRLISLMGFKL 6019
Query 63 NYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPT 122
+ ++GY FIT++EAI+ VR W+GFDVEG HATR+ +GTN PLQ+GFSTGV+ V T
Sbjct 6020 DLTLDGYSKFFITKDEAIKRVRGWVGFDVEGAHATRDNIGTNFPLQIGFSTGVDFVVEAT 6079
Query 123 GYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVV 182
G + F R AK PPGD FKHLIPLM KG W+VVRI+IVQMLSD L +LSD VV
Sbjct 6080 GLFAERDCYIFKRTVAKAPPGDNFKHLIPLMSKGQKWDVVRIRIVQMLSDYLLDLSDSVV 6139
Query 183 FVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMI 242
F+ W+ FELT ++YF K+G E C +C RATC+++ + Y CW HS DYVYNP ++
Sbjct 6140 FITWSASFELTCLRYFAKLGRELNCDVCPNRATCYNSRTGYYGCWRHSYTCDYVYNPLIV 6199
Query 243 DVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDE 302
D+QQWG+TG+L SNHD+ C VH AHVAS DAIMTRCLA+++CF K V+W +EYPII +E
Sbjct 6200 DIQQWGYTGSLTSNHDIICNVHKGAHVASSDAIMTRCLAIYDCFCKSVNWNLEYPIISNE 6259
Query 303 LKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYK 362
+ IN +CR +Q +++KAA+L +++ + +DIGNPK I CV D E+KFYDA P
Sbjct 6260 VSINTSCRLLQRVMLKAAMLCNRYNLCYDIGNPKGIACVK--DYEFKFYDASPV---VKS 6314
Query 363 IEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVN 422
+++LFY Y H D F DG+C+FWNCNVD+YP+NSIVCRFDTRVL+ LNLPGC+GGSLYVN
Sbjct 6315 VKQLFYVYDVHKDNFKDGLCMFWNCNVDKYPSNSIVCRFDTRVLNKLNLPGCNGGSLYVN 6374
Query 423 KHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGA 482
KHAFHT F ++ F NLK +PFFYYSD+PC +DYVPL+SATCITRCNLGGA
Sbjct 6375 KHAFHTNPFTRTVFENLKPMPFFYYSDTPCVYVDGLESKQVDYVPLRSATCITRCNLGGA 6434
Query 483 VCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
VC HA +Y YL++YN+ +AGF+ WVYK FD YNLWNTFT LQ
Sbjct 6435 VCSKHAEDYCKYLESYNVATTAGFTFWVYKTFDFYNLWNTFTMLQ 6479
>sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=rep PE=1 SV=1
Length=6781
Score = 875 bits (2260), Expect = 0.0, Method: Composition-based stats.
Identities = 270/521 (52%), Positives = 351/521 (67%), Gaps = 11/521 (2%)
Query 5 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNY 64
GLFKDCS+ L P+ A T +S+ FKT+ G+ + Y +IS MGF+ +
Sbjct 5629 CGLFKDCSRGDDLLPPSHANTFMSLADNFKTDQYLAVQIGVNGPIKYEHVISFMGFRFDI 5688
Query 65 QVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGY 124
+ + +F TR+ A+R+VR W+GFDVEG H VGTN+PLQLGFS GV+ V P G
Sbjct 5689 NIPNHHTLFCTRDFAMRNVRGWLGFDVEGAHVVGSNVGTNVPLQLGFSNGVDFVVRPEGC 5748
Query 125 VDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFV 184
V T + V A+ PPG+QF HL+PL+ +G PW+VVR +IVQM SD L NLSD ++FV
Sbjct 5749 VVTESGDYIKPVRARAPPGEQFAHLLPLLKRGQPWDVVRKRIVQMCSDYLANLSDILIFV 5808
Query 185 LWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDV 244
LWA G ELT+M+YFVKIGP ++C C + ATC+++A TY C+ H++G DY+YNP+ ID+
Sbjct 5809 LWAGGLELTTMRYFVKIGPSKSC-DCGKVATCYNSALHTYCCFKHALGCDYLYNPYCIDI 5867
Query 245 QQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELK 304
QQWG+ G+L NH +C VH N HVAS DAIMTRCLA+H+CFVK VDW+I YP IG+E
Sbjct 5868 QQWGYKGSLSLNHHEHCNVHRNEHVASGDAIMTRCLAIHDCFVKNVDWSITYPFIGNEAV 5927
Query 305 INAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIE 364
IN + R VQ +++ L ++DIGNPK I+C D +W +D P + +E
Sbjct 5928 INKSGRIVQSHTMRSVLKLYNPKAIYDIGNPKGIRCA-VTDAKWFCFDKNPTNSNVKTLE 5986
Query 365 ELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKH 424
Y Y TH DG+CLFWNCNVD YP S+VCRFDTR S LNL GC+GGSLYVN H
Sbjct 5987 ---YDYITHGQ--FDGLCLFWNCNVDMYPEFSVVCRFDTRCRSPLNLEGCNGGSLYVNNH 6041
Query 425 AFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVC 484
AFHTPAFDK AF LK +PFF+Y D+ C+ ++ I+YVPL+++ CIT+CN+GGAVC
Sbjct 6042 AFHTPAFDKRAFAKLKPMPFFFYDDTECD----KLQDSINYVPLRASNCITKCNVGGAVC 6097
Query 485 RHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTR 525
H Y Y++AYN SAGF++WV FDTYNLW TF+
Sbjct 6098 SKHCAMYHSYVNAYNTFTSAGFTIWVPTSFDTYNLWQTFSN 6138
>sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavirus
OC43 OX=31631 GN=rep PE=1 SV=1
Length=7095
Score = 873 bits (2255), Expect = 0.0, Method: Composition-based stats.
Identities = 302/527 (57%), Positives = 389/527 (74%), Gaps = 6/527 (1%)
Query 2 ENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK-TEGLCVDIPGIPKDMTYRRLISMMGF 60
+ T LFKDCSK +G HP AP+ L+VD K+K T L V + +TY RLIS+MGF
Sbjct 5900 QCSTNLFKDCSKSYSGYHPAHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGF 5959
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
K++ ++GY +FIT+EEA++ VRAW+GFD EG HAT +++GTN PLQLGFSTG++ V
Sbjct 5960 KLDVTLDGYCKLFITKEEAVKRVRAWVGFDAEGAHATLDSIGTNFPLQLGFSTGIDFVVE 6019
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
TG + F + AK PPG+QFKHLIPLM +G W+VVR +IVQM +D L +LSD
Sbjct 6020 ATGLFADRDGYSFKKAVAKAPPGEQFKHLIPLMTRGHRWDVVRPRIVQMFADHLIDLSDC 6079
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
VV V WA FELT ++YF K+G E +C +C +RAT +++ + Y CW HS+ DY+YNP
Sbjct 6080 VVLVTWAANFELTCLRYFAKVGREISCNVCTKRATVYNSRTGYYGCWRHSVTCDYLYNPL 6139
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
++D+QQWG+ G+L SNHDLYC VH AHVAS DAIMTRCLAV++CF ++W +EYPII
Sbjct 6140 IVDIQQWGYIGSLSSNHDLYCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIIS 6199
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
+EL IN +CR +Q +++KAA+L +++ + +DIGNPK I CV D ++KFYDAQP
Sbjct 6200 NELSINTSCRVLQRVILKAAMLCNRYTLCYDIGNPKGIACVK--DFDFKFYDAQPI---V 6254
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
++ L YS+ H D F DG+C+FWNCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLY
Sbjct 6255 KSVKTLLYSFEAHKDSFKDGLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLY 6314
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VNKHAFHT F ++AF +LK +PFFYYSD+PC +DYVPLKSATCITRCNLG
Sbjct 6315 VNKHAFHTKPFARAAFEHLKPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLG 6374
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GAVC HA EYR YL++YN +AGF+ WVYK FD YNLWNTFT+LQ
Sbjct 6375 GAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTKLQ 6421
>sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=rep PE=3 SV=1
Length=7059
Score = 872 bits (2254), Expect = 0.0, Method: Composition-based stats.
Identities = 302/527 (57%), Positives = 389/527 (74%), Gaps = 6/527 (1%)
Query 2 ENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK-TEGLCVDIPGIPKDMTYRRLISMMGF 60
+ T LFKDCSK +G HP AP+ L+VD K+K T L V + +TY RLIS+MGF
Sbjct 5900 QCSTNLFKDCSKSYSGYHPAHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGF 5959
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
K++ ++GY +FIT+EEA++ VRAW+GFD EG HATR+++GTN PLQLGFSTG++ V
Sbjct 5960 KLDVTLDGYCKLFITKEEAVKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVE 6019
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
TG + F + AK PPG+QFKHLIPLM +G W+VVR +IVQM +D L +LSD
Sbjct 6020 ATGLFADRDGYSFKKAVAKAPPGEQFKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDC 6079
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
VV V WA FELT ++YF K+G E +C + +RAT +++ + Y CW HS+ DY+YNP
Sbjct 6080 VVLVTWAANFELTCLRYFAKVGREISCNVSTKRATAYNSRTGYYGCWRHSVTCDYLYNPL 6139
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
++D+QQWG+ G+L SNHDLYC VH AHVAS DAIMTRCLAV++CF ++W +EYPII
Sbjct 6140 IVDIQQWGYIGSLSSNHDLYCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIIS 6199
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
+EL IN +CR +Q +++KAA+L +++ + +DIGNPKAI CV D ++KFYDAQP
Sbjct 6200 NELSINTSCRVLQRVMLKAAMLCNRYTLCYDIGNPKAIACVK--DFDFKFYDAQPI---V 6254
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
++ L Y + H D F DG+C+FWNCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLY
Sbjct 6255 KSVKTLLYFFEAHKDSFKDGLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLY 6314
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VNKHAFHT F ++AF +LK +PFFYYSD+PC +DYVPLKSATCITRCNLG
Sbjct 6315 VNKHAFHTKPFSRAAFEHLKPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLG 6374
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GAVC HA EYR YL++YN +AGF+ WVYK FD YNLWNTFT+LQ
Sbjct 6375 GAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTKLQ 6421
>sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus
512/2005 OX=693999 GN=rep PE=3 SV=1
Length=6793
Score = 871 bits (2251), Expect = 0.0, Method: Composition-based stats.
Identities = 269/521 (52%), Positives = 346/521 (66%), Gaps = 11/521 (2%)
Query 5 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNY 64
GLFKDC K L P+ APT +S+ FKT+ G+ + Y +IS MGF+ +
Sbjct 5640 CGLFKDCYKGEDNLPPSHAPTFMSLSDNFKTDKDLAVQIGVNGPVKYEHVISFMGFRFDI 5699
Query 65 QVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGY 124
V +F TR+ A+R+ R W+GFDVEG H VGTN+PLQLGFS GV+ V P G
Sbjct 5700 NVPNQHTLFCTRDFAMRNARGWLGFDVEGAHVIGSNVGTNVPLQLGFSNGVDFVVRPEGC 5759
Query 125 VDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFV 184
V T V A+ PPGDQF HL+PL+ KG PW+V+R +IVQM SD L NLSD ++FV
Sbjct 5760 VSTEVGDVIQPVRARAPPGDQFTHLLPLLRKGQPWSVIRRRIVQMCSDYLANLSDTLIFV 5819
Query 185 LWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDV 244
LW+ G ELT+M+YFVK+GP +TC C +RATC+++ + T++C+ H++G DY+YN + ID+
Sbjct 5820 LWSGGLELTTMRYFVKLGPVQTC-DCGKRATCYNSTNHTFSCFRHALGSDYIYNCYCIDI 5878
Query 245 QQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELK 304
QQWG+TG+L NH C +H N HVAS DA MTRCLA+H+CFVK VDW+I YP I +E
Sbjct 5879 QQWGYTGSLSMNHHEVCNIHRNEHVASGDAAMTRCLAIHDCFVKNVDWSITYPFIANEQA 5938
Query 305 INAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIE 364
IN + R VQ V++A L +HD+GNPK I+CV D W YD P + +E
Sbjct 5939 INKSGRLVQSHVMRAVLKLYNPKAIHDVGNPKGIRCV-VTDASWYCYDKNPTNTNVKMLE 5997
Query 365 ELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKH 424
Y Y TH DG+CLFWNCNVD YP S+VCRFDTR+ S LNL GC+GGSLYVN H
Sbjct 5998 ---YDYITHGQ--LDGLCLFWNCNVDMYPEFSVVCRFDTRMRSTLNLEGCNGGSLYVNNH 6052
Query 425 AFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVC 484
AFHTPA+DK AF LK +PFF+Y DS CE ++ ++YVPL+++ CITRCN+GGAVC
Sbjct 6053 AFHTPAYDKRAFAKLKAMPFFFYDDSECE----KLQDAVNYVPLRASNCITRCNVGGAVC 6108
Query 485 RHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTR 525
H Y Y+ AYN +AGF++WV FD +NLW TF
Sbjct 6109 SKHCALYHNYVMAYNTFTTAGFTIWVPNSFDMFNLWQTFKN 6149
>sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavirus
229E OX=11137 GN=rep PE=1 SV=1
Length=6758
Score = 869 bits (2246), Expect = 0.0, Method: Composition-based stats.
Identities = 273/527 (52%), Positives = 352/527 (67%), Gaps = 11/527 (2%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 60
+E+ GLFKDC++ L P+ A T+LS+ +FKT G G TY +IS MGF
Sbjct 5593 SESSCGLFKDCARNPIDLPPSHATTYLSLSDRFKTSGDLAVQIGNNNVCTYEHVISYMGF 5652
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
+ + + G ++F TR+ A+RHVR W+G DVEG H T + VGTN+PLQ+GFS GV+ VA
Sbjct 5653 RFDVSMPGSHSLFCTRDFAMRHVRGWLGMDVEGAHVTGDNVGTNVPLQVGFSNGVDFVAQ 5712
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
P G V T + V A+ PPG+QF H++PL+ KG PW+V+R +IVQM++D L SD
Sbjct 5713 PEGCVLTNTGSVVKPVRARAPPGEQFTHIVPLLRKGQPWSVLRKRIVQMIADFLAGSSDV 5772
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
+VFVLWA G ELT+M+YFVKIG + C C ATC+++ S+ Y C+ H++G DYVYNP+
Sbjct 5773 LVFVLWAGGLELTTMRYFVKIGAVKHC-QCGTVATCYNSVSNDYCCFKHALGCDYVYNPY 5831
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
+ID+QQWG+ G+L +NH C VH N HVAS DAIMTRCLAV++CFVK VDW+I YP+I
Sbjct 5832 VIDIQQWGYVGSLSTNHHAICNVHRNEHVASGDAIMTRCLAVYDCFVKNVDWSITYPMIA 5891
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
+E IN R VQ +++AA+ +HDIGNPK I+C D +W YD P +
Sbjct 5892 NENAINKGGRTVQSHIMRAAIKLYNPKAIHDIGNPKGIRCA-VTDAKWYCYDKNPINSNV 5950
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
+E Y Y TH DG+CLFWNCNVD YP SIVCRFDTR S LNL G +GGSLY
Sbjct 5951 KTLE---YDYMTHGQ--MDGLCLFWNCNVDMYPEFSIVCRFDTRTRSTLNLEGVNGGSLY 6005
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VN HAFHTPA+DK A LK PFFYY D CE ++YVPL++ CIT+CN+G
Sbjct 6006 VNNHAFHTPAYDKRAMAKLKPAPFFYYDDGSCEVVH----DQVNYVPLRATNCITKCNIG 6061
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GAVC HAN YR Y+++YN+ AGF++WV FD YNLW TFT +
Sbjct 6062 GAVCSKHANLYRAYVESYNIFTQAGFNIWVPTTFDCYNLWQTFTEVN 6108
>sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=rep PE=3 SV=1
Length=7094
Score = 869 bits (2245), Expect = 0.0, Method: Composition-based stats.
Identities = 301/527 (57%), Positives = 388/527 (74%), Gaps = 6/527 (1%)
Query 2 ENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK-TEGLCVDIPGIPKDMTYRRLISMMGF 60
+ T LFKDCSK +G HP AP+ L+VD K+K T L V + +TY RL S+MGF
Sbjct 5900 QCSTNLFKDCSKSYSGYHPAHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRLTSLMGF 5959
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
K++ ++GY +FIT+EEA++ VRAW+GFD EG HATR+++GTN PLQLGFSTG++ V
Sbjct 5960 KLDVTLDGYCKLFITKEEAVKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVE 6019
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
TG + F + AK PPG+QFKHLIPLM +G W+VVR +IVQM +D L +LSD
Sbjct 6020 ATGLFADRDGYSFKKAVAKAPPGEQFKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDC 6079
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
VV V WA FELT ++YF K+G E +C +C +RAT +++ + Y CW HS+ DY+YNP
Sbjct 6080 VVLVTWAANFELTCLRYFAKVGREISCNVCTKRATAYNSRTGYYGCWRHSVTCDYLYNPL 6139
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
++D+QQWG+ G+L SNHDLYC VH AHVAS DAIMTRCLAV++CF ++W +EYPII
Sbjct 6140 IVDIQQWGYIGSLSSNHDLYCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIIS 6199
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
+EL IN +CR +Q +++KAA+L +++ + +DIGNPKAI CV D ++KFYDAQP
Sbjct 6200 NELSINTSCRVLQRVMLKAAMLCNRYTLCYDIGNPKAIACVK--DFDFKFYDAQPI---V 6254
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
++ L Y + H D F DG+C+FWNCNVD+YP N++VCRFDTRVL+NLNLPGC+GGSLY
Sbjct 6255 KSVKTLLYFFEAHKDSFKDGLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLY 6314
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VNKHAFHT F ++AF +LK +PFFYYSD+PC +DYVPLKSATCITRCNL
Sbjct 6315 VNKHAFHTKPFSRAAFEHLKPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLV 6374
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GAVC HA EYR YL++YN +AGF+ WVYK FD YNLWNTFT+LQ
Sbjct 6375 GAVCLKHAEEYREYLNSYNTATTAGFTFWVYKTFDFYNLWNTFTKLQ 6421
>sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavirus
(strain JHM) OX=11144 GN=rep PE=1 SV=1
Length=7180
Score = 868 bits (2243), Expect = 0.0, Method: Composition-based stats.
Identities = 302/527 (57%), Positives = 386/527 (73%), Gaps = 8/527 (2%)
Query 2 ENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEG-LCVDIPGIPKDMTYRRLISMMGF 60
+ T LFKDCSK G+ P L+VD K+K G L V + +TY RLIS+MGF
Sbjct 5988 QCTTNLFKDCSKSYVGIPP--CAFLLAVDDKYKVSGNLAVCLNVADSAVTYSRLISLMGF 6045
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
K++ ++GY +FITR+EAI+ VRAW+GFD EG HATR+++GTN PLQLGFSTG++ V
Sbjct 6046 KLDLTLDGYCKLFITRDEAIKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVE 6105
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
TG + F + +A+ PPG+QFKHL+PLM +G W+VVRI+IVQMLSD L +L+D
Sbjct 6106 ATGMFAERDGYVFKKAAARAPPGEQFKHLVPLMSRGQKWDVVRIRIVQMLSDHLVDLADS 6165
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
VV V WA FELT ++YF K+G E C +C++RATCF++ + Y CW HS DY+YNP
Sbjct 6166 VVLVTWAASFELTCLRYFAKVGKEVVCSVCNKRATCFNSRTGYYGCWRHSYSCDYLYNPL 6225
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
++D+QQWG+TG+L SNHD C VH AHVAS DAIMTRCLAVH+CF K V+W +EYPII
Sbjct 6226 IVDIQQWGYTGSLTSNHDPICSVHKGAHVASSDAIMTRCLAVHDCFCKSVNWNLEYPIIS 6285
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
+E+ +N +CR +Q ++ +AA+L +++ V +DIGNPK + CV D +KFYDA P
Sbjct 6286 NEVSVNTSCRLLQRVMFRAAMLCNRYDVCYDIGNPKGLACVKGYD--FKFYDASPV---V 6340
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
+++ Y Y H D+F DG+C+FWNCNVD+YPAN++VCRFDTRVLS LNLPGC+GGSLY
Sbjct 6341 KSVKQFVYKYEAHKDQFLDGLCMFWNCNVDKYPANAVVCRFDTRVLSKLNLPGCNGGSLY 6400
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VNKHAFHT F ++AF NLK +PFFYYSD+PC +DYVPL+SATCITRCNLG
Sbjct 6401 VNKHAFHTNPFTRAAFENLKPMPFFYYSDTPCVYMEGMESKQVDYVPLRSATCITRCNLG 6460
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
GAVC HA EYR YL++YN +AGF+ WVYK FD YNLWNTFTRLQ
Sbjct 6461 GAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTRLQ 6507
>sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavirus
NL63 OX=277944 GN=rep PE=1 SV=1
Length=6729
Score = 861 bits (2225), Expect = 0.0, Method: Composition-based stats.
Identities = 280/529 (53%), Positives = 353/529 (67%), Gaps = 13/529 (2%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGF 60
+ V GLFK+C++ L PT A T LS+ +FKT G G TY +IS MGF
Sbjct 5568 SSQVCGLFKNCTRTPLNLPPTHAHTFLSLSDQFKTTGDLAVQIGSNNVCTYEHVISFMGF 5627
Query 61 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAV 120
+ + + G ++F TR+ AIR+VR W+G DVE H + +GTN+PLQ+GFS GVN V
Sbjct 5628 RFDISIPGSHSLFCTRDFAIRNVRGWLGMDVESAHVCGDNIGTNVPLQVGFSNGVNFVVQ 5687
Query 121 PTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDR 180
G V T V AK PPG+QF+HLIPL+ KG PW +VR +IVQM+SD L NLSD
Sbjct 5688 TEGCVSTNFGDVIKPVCAKSPPGEQFRHLIPLLRKGQPWLIVRRRIVQMISDYLSNLSDI 5747
Query 181 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPF 240
+VFVLWA ELT+M+YFVKIGP + C C ATC+++ S+ Y C+ H++G DYVYNP+
Sbjct 5748 LVFVLWAGSLELTTMRYFVKIGPIKYC-YCGNSATCYNSVSNEYCCFKHALGCDYVYNPY 5806
Query 241 MIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIG 300
D+QQWG+ G+L NH +C +H N H AS DA+MTRCLAVH+CFVK VDWT+ YP I
Sbjct 5807 AFDIQQWGYVGSLSQNHHTFCNIHRNEHDASGDAVMTRCLAVHDCFVKNVDWTVTYPFIA 5866
Query 301 DELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKA 360
+E IN R VQ VV+AAL K V+HDIGNPK ++C D +W YD QP +
Sbjct 5867 NEKFINGCGRNVQGHVVRAALKLYKPSVIHDIGNPKGVRCA-VTDAKWYCYDKQPVNSN- 5924
Query 361 YKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLY 420
++ L Y YATH DG+CLFWNCNVD YP SIVCRFDTR S NL G +GGSLY
Sbjct 5925 --VKLLDYDYATHGQ--LDGLCLFWNCNVDMYPEFSIVCRFDTRTRSVFNLEGVNGGSLY 5980
Query 421 VNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 480
VNKHAFHTPA+DK AFV LK +PFFY+ DS C+ ++YVPL++++C+TRCN+G
Sbjct 5981 VNKHAFHTPAYDKRAFVKLKPMPFFYFDDSDCDVVQ----EQVNYVPLRASSCVTRCNIG 6036
Query 481 GAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTF--TRLQ 527
GAVC HAN Y+ Y++AYN AGF++WV FD YNLW F T LQ
Sbjct 6037 GAVCSKHANLYQKYVEAYNTFTQAGFNIWVPHSFDVYNLWQIFIETNLQ 6085
>sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus
HKU9 OX=694006 GN=rep PE=1 SV=1
Length=6930
Score = 861 bits (2225), Expect = 0.0, Method: Composition-based stats.
Identities = 321/534 (60%), Positives = 388/534 (73%), Gaps = 11/534 (2%)
Query 1 AENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFK-TEGLCVDIPGIPKDMTYRRLISMMG 59
+E GLFKDC+K L P APT +SV+ KFK E LCV M Y RLIS MG
Sbjct 5767 SEVTVGLFKDCAKAE-PLGPAYAPTFVSVNDKFKLNESLCVHFDTTELQMPYNRLISKMG 5825
Query 60 FKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVA 119
FK + + GY +FITRE+AIR VR W+GFDVEG HA +GTNLPLQ+GFSTGVN V
Sbjct 5826 FKFDLNIPGYSKLFITREQAIREVRGWVGFDVEGAHACGPNIGTNLPLQIGFSTGVNFVV 5885
Query 120 VPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSD 179
P+GY+DT + + + V +K PPGDQFKHLIPLM KG PW+VVR +IV+ML DTL +SD
Sbjct 5886 TPSGYIDTESGSRLANVVSKAPPGDQFKHLIPLMRKGEPWSVVRKRIVEMLCDTLDGVSD 5945
Query 180 RVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSI---GFDYV 236
V FV WAHGFELT++ YF K+GPER C +C RRAT FS+ Y+CW H G D+V
Sbjct 5946 TVTFVTWAHGFELTTLHYFAKVGPERKCFMCPRRATLFSSVYGAYSCWSHHRHIGGADFV 6005
Query 237 YNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEY 296
YNPF++DVQQWG+ GNLQ NHD C VH AHVASCDAIMTRCLA+H+CF V+W +EY
Sbjct 6006 YNPFLVDVQQWGYVGNLQVNHDNVCDVHKGAHVASCDAIMTRCLAIHDCFCGEVNWDVEY 6065
Query 297 PIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPC 356
PII +EL IN ACR VQ +V+KAA+ A ++DIGNPKAIK W FYD P
Sbjct 6066 PIIANELAINRACRSVQRVVLKAAVKALHIETIYDIGNPKAIKVYGVNVNNWNFYDTNPV 6125
Query 357 SDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDG 416
+++L Y Y H D+F DG+ +FWNCNVD YP N++VCRFDTRVLS LNL GC+G
Sbjct 6126 ---VEGVKQLHYVYDVHRDQFKDGLAMFWNCNVDCYPHNALVCRFDTRVLSKLNLAGCNG 6182
Query 417 GSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCES---HGKQVVSDIDYVPLKSATC 473
GSLYVN+HAFHT AF+K+AFVNLK LPFFYYSD+ CE+ VS++DYVPLKS C
Sbjct 6183 GSLYVNQHAFHTDAFNKNAFVNLKPLPFFYYSDTACENATGVSTNYVSEVDYVPLKSNVC 6242
Query 474 ITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
ITRCNLGGAVC+ HA+EYR +L++YN M+SAGF+LWV K FD +NLW+TF +LQ
Sbjct 6243 ITRCNLGGAVCKKHADEYRNFLESYNTMVSAGFTLWVDKTFDVFNLWSTFVKLQ 6296
>sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavirus
(strain FIPV WSU-79/1146) OX=33734 GN=rep PE=1 SV=2
Length=6709
Score = 860 bits (2223), Expect = 0.0, Method: Composition-based stats.
Identities = 278/523 (53%), Positives = 351/523 (67%), Gaps = 14/523 (3%)
Query 4 VTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKM 62
GLFKDCSK + P A T++S+ FKT +GL V+I KD+ Y +IS MGF+
Sbjct 5556 TCGLFKDCSKSEQYIPPAYATTYMSLSDNFKTSDGLAVNIG--TKDVKYANVISYMGFRF 5613
Query 63 NYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPT 122
+ GY +F TR+ A+R+VRAW+GFDVEG H + VGTN+PLQLGFS GV+ V
Sbjct 5614 EANIPGYHTLFCTRDFAMRNVRAWLGFDVEGAHVCGDNVGTNVPLQLGFSNGVDFVVQTE 5673
Query 123 GYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVV 182
G V T V A+ PPG+QF HLIPLM KG PW++VR +IVQM+ D LSD ++
Sbjct 5674 GCVVTEKGNSIEVVKARAPPGEQFAHLIPLMRKGQPWHIVRRRIVQMVCDYFDGLSDILI 5733
Query 183 FVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMI 242
FVLWA G ELT+M+YFVKIG + C C + ATC+S++ YAC+ H++G DY+YNP+ I
Sbjct 5734 FVLWAGGLELTTMRYFVKIGRPQKCE-CGKSATCYSSSQCVYACFKHALGCDYLYNPYCI 5792
Query 243 DVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDE 302
D+QQWG+TG+L NH C +H N HVAS DAIMTRCLA+H+CFVKRVDW+I YP I +E
Sbjct 5793 DIQQWGYTGSLSMNHHEVCNIHRNEHVASGDAIMTRCLAIHDCFVKRVDWSIVYPFIDNE 5852
Query 303 LKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYK 362
KIN A R VQ V+KAAL +HD+GNPK I+C + W YD P ++
Sbjct 5853 EKINKAGRIVQSHVMKAALKIFNPAAIHDVGNPKGIRCATTP-IPWFCYDRDPINNNVRC 5911
Query 363 IEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVN 422
+E Y Y H +G+ LFWNCNVD YP SIVCRFDTR S L+L GC+GG+LYVN
Sbjct 5912 LE---YDYMVHGQ--MNGLMLFWNCNVDMYPEFSIVCRFDTRTRSKLSLEGCNGGALYVN 5966
Query 423 KHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGA 482
HAFHTPA+D+ AF LK +PFFYY DS CE Q +YVPLKS CIT+CN+GGA
Sbjct 5967 NHAFHTPAYDRRAFAKLKPMPFFYYDDSNCELVDGQP----NYVPLKSNVCITKCNIGGA 6022
Query 483 VCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTR 525
VC+ HA YR Y++ YNM + AGF++W + FDTY LW+ F
Sbjct 6023 VCKKHAALYRAYVEDYNMFMQAGFTIWCPQNFDTYMLWHGFVN 6065
>sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=rep PE=1 SV=1
Length=6684
Score = 858 bits (2217), Expect = 0.0, Method: Composition-based stats.
Identities = 277/523 (53%), Positives = 350/523 (67%), Gaps = 14/523 (3%)
Query 4 VTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKM 62
GLFKDCSK + P A T++S+ FKT +GL V+I KD+ Y +IS MGF+
Sbjct 5531 TCGLFKDCSKSEQYIPPAYATTYMSLSDNFKTSDGLAVNIG--TKDVKYANVISYMGFRF 5588
Query 63 NYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPT 122
+ GY +F TR+ A+R+VRAW+GFDVEG H + VGTN+PLQLGFS GV+ V
Sbjct 5589 EANIPGYHTLFCTRDFAMRNVRAWLGFDVEGAHVCGDNVGTNVPLQLGFSNGVDFVVQTE 5648
Query 123 GYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVV 182
G V T V A+ PPG+QF HLIPLM KG PW++VR +IVQM+ D LSD ++
Sbjct 5649 GCVITEKGNSIEVVKARAPPGEQFAHLIPLMRKGQPWHIVRRRIVQMVCDYFDGLSDILI 5708
Query 183 FVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMI 242
FVLWA G ELT+M+YFVKIG + C C + ATC+S++ YAC+ H++G DY+YNP+ I
Sbjct 5709 FVLWAGGLELTTMRYFVKIGRPQKCE-CGKSATCYSSSQSVYACFKHALGCDYLYNPYCI 5767
Query 243 DVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDE 302
D+QQWG+TG+L NH C +H N HVAS DAIMTRCLA+H+CFVKRVDW+I YP I +E
Sbjct 5768 DIQQWGYTGSLSMNHHEVCNIHRNEHVASGDAIMTRCLAIHDCFVKRVDWSIVYPFIDNE 5827
Query 303 LKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYK 362
KIN A R VQ V+KAAL +HD+GNPK I+C + W YD P ++
Sbjct 5828 EKINKAGRIVQSHVMKAALKIFNPAAIHDVGNPKGIRCATTP-IPWFCYDRDPINNNVRC 5886
Query 363 IEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVN 422
L Y Y H +G+ LFWNCNVD YP SIVCRFDTR S L+L GC+GG+LYVN
Sbjct 5887 ---LDYDYMVHGQ--MNGLMLFWNCNVDMYPEFSIVCRFDTRTRSKLSLEGCNGGALYVN 5941
Query 423 KHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGA 482
HAFHTPA+D+ AF LK +PFFYY DS CE Q +YVPLKS CIT+CN+GGA
Sbjct 5942 NHAFHTPAYDRRAFAKLKPMPFFYYDDSNCELVDGQP----NYVPLKSNVCITKCNIGGA 5997
Query 483 VCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTR 525
VC+ HA YR Y++ YN+ + AGF++W + FDTY LW+ F
Sbjct 5998 VCKKHAALYRAYVEDYNIFMQAGFTIWCPQNFDTYMLWHGFVN 6040
>sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=rep PE=1 SV=1
Length=6631
Score = 825 bits (2132), Expect = 0.0, Method: Composition-based stats.
Identities = 277/525 (53%), Positives = 367/525 (70%), Gaps = 7/525 (1%)
Query 5 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIP--KDMTYRRLISMMGFKM 62
TGLFK C+K +G+HP A T ++ +K + + ++TY+ LIS++GFKM
Sbjct 5472 TGLFKICNKEFSGVHPAYAVTTKALAATYKVNDELAALVNVEAGSEITYKHLISLLGFKM 5531
Query 63 NYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPT 122
+ V G NMFITR+EAIR+VR W+GFDVE HA +GTNLP Q+GFSTG + V P
Sbjct 5532 SVNVEGCHNMFITRDEAIRNVRGWVGFDVEATHACGTNIGTNLPFQVGFSTGADFVVTPE 5591
Query 123 GYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVV 182
G VDT +F V++K PPG+QF HL L PW+VVR +IVQML+D L N+SD VV
Sbjct 5592 GLVDTSIGNNFEPVNSKAPPGEQFNHLRALFKSAKPWHVVRPRIVQMLADNLCNVSDCVV 5651
Query 183 FVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMI 242
FV W HG ELT+++YFVKIG ++ C C RAT F++ + YACW H +GFD+VYNP ++
Sbjct 5652 FVTWCHGLELTTLRYFVKIGKDQVCS-CGSRATTFNSHTQAYACWKHCLGFDFVYNPLLV 5710
Query 243 DVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDE 302
D+QQWG++GNLQ NHDL+C VHG+AHVAS DAIMTRCLA++ F + V+W + YP I +E
Sbjct 5711 DIQQWGYSGNLQFNHDLHCNVHGHAHVASADAIMTRCLAINNAFCQDVNWDLTYPHIANE 5770
Query 303 LKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYK 362
++N++CR +Q M + A + A K V++DIGNPK IKCV + D+ ++FYD P +
Sbjct 5771 DEVNSSCRYLQRMYLNACVDALKVNVVYDIGNPKGIKCVRRGDLNFRFYDKNPIVPNVKQ 5830
Query 363 IEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVN 422
E Y Y H DKF DG+C+FWNCNVD YP NS+VCR+DTR LS NLPGC+GGSLYVN
Sbjct 5831 FE---YDYNQHKDKFADGLCMFWNCNVDCYPDNSLVCRYDTRNLSVFNLPGCNGGSLYVN 5887
Query 423 KHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGA 482
KHAFHTP FD+++F NLK +PFF+Y SPCE+ V+ D V L + CIT+CN+GGA
Sbjct 5888 KHAFHTPKFDRTSFRNLKAMPFFFYDSSPCETIQLDGVAQ-DLVSLATKDCITKCNIGGA 5946
Query 483 VCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
VC+ HA Y ++ +YN ++AGF+ WV F+ YNLW +F+ LQ
Sbjct 5947 VCKKHAQMYADFVTSYNAAVTAGFTFWVTNNFNPYNLWKSFSALQ 5991
>sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=rep
PE=3 SV=1
Length=6629
Score = 814 bits (2102), Expect = 0.0, Method: Composition-based stats.
Identities = 276/525 (53%), Positives = 366/525 (70%), Gaps = 7/525 (1%)
Query 5 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIP--KDMTYRRLISMMGFKM 62
TGLFK C+K +G+HP A T ++ +K + + ++TY+ LIS++GFKM
Sbjct 5470 TGLFKICNKEFSGVHPAYAVTTKALAATYKVNDELAALVNVEAGSEITYKHLISLLGFKM 5529
Query 63 NYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPT 122
+ V G NMFITR+EAIR+VR W+GFDVE HA +GTNLP Q+GFSTG + V P
Sbjct 5530 SVNVEGCHNMFITRDEAIRNVRGWVGFDVEATHACGTNIGTNLPFQVGFSTGADFVVTPE 5589
Query 123 GYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVV 182
G VDT +F V++K PPG+QF HL L PW+V+R +IVQML+D L N+SD VV
Sbjct 5590 GLVDTSIGNNFEPVNSKAPPGEQFNHLRVLFKSAKPWHVIRPRIVQMLADNLCNVSDCVV 5649
Query 183 FVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMI 242
FV W HG ELT+++YFVKIG E+ C C RAT F++ + YACW H +GFD+VYNP ++
Sbjct 5650 FVTWCHGLELTTLRYFVKIGKEQVCS-CGSRATTFNSHTQAYACWKHCLGFDFVYNPLLV 5708
Query 243 DVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDE 302
D+QQWG++GNLQ NHDL+C VHG+AHVAS DAIMTRCLA++ F + V+W + YP I +E
Sbjct 5709 DIQQWGYSGNLQFNHDLHCNVHGHAHVASVDAIMTRCLAINNAFCQDVNWDLTYPHIANE 5768
Query 303 LKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYK 362
++N++CR +Q M + A + A K V++DIGNPK IKCV + DV ++FYD P +
Sbjct 5769 DEVNSSCRYLQRMYLNACVDALKVNVVYDIGNPKGIKCVRRGDVNFRFYDKNPIVRNVKQ 5828
Query 363 IEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVN 422
E Y Y H DKF DG+C+FWNCNVD YP NS+VCR+DTR LS NLPGC+GGSLYVN
Sbjct 5829 FE---YDYNQHKDKFADGLCMFWNCNVDCYPDNSLVCRYDTRNLSVFNLPGCNGGSLYVN 5885
Query 423 KHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGA 482
KHAF+TP FD+ +F NLK +PFF+Y SPCE+ V+ D V L + CIT+CN+GGA
Sbjct 5886 KHAFYTPKFDRISFRNLKAMPFFFYDSSPCETIQVDGVAQ-DLVSLATKDCITKCNIGGA 5944
Query 483 VCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
VC+ HA Y ++ +YN ++AGF+ WV + + YNLW +F+ LQ
Sbjct 5945 VCKKHAQMYAEFVTSYNAAVTAGFTFWVTNKLNPYNLWKSFSALQ 5989
>sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=rep PE=1
SV=1
Length=6629
Score = 814 bits (2102), Expect = 0.0, Method: Composition-based stats.
Identities = 276/525 (53%), Positives = 366/525 (70%), Gaps = 7/525 (1%)
Query 5 TGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIP--KDMTYRRLISMMGFKM 62
TGLFK C+K +G+HP A T ++ +K + + ++TY+ LIS++GFKM
Sbjct 5470 TGLFKICNKEFSGVHPAYAVTTKALAATYKVNDELAALVNVEAGSEITYKHLISLLGFKM 5529
Query 63 NYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPT 122
+ V G NMFITR+EAIR+VR W+GFDVE HA +GTNLP Q+GFSTG + V P
Sbjct 5530 SVNVEGCHNMFITRDEAIRNVRGWVGFDVEATHACGTNIGTNLPFQVGFSTGADFVVTPE 5589
Query 123 GYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVV 182
G VDT +F V++K PPG+QF HL L PW+V+R +IVQML+D L N+SD VV
Sbjct 5590 GLVDTSIGNNFEPVNSKAPPGEQFNHLRVLFKSAKPWHVIRPRIVQMLADNLCNVSDCVV 5649
Query 183 FVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMI 242
FV W HG ELT+++YFVKIG E+ C C RAT F++ + YACW H +GFD+VYNP ++
Sbjct 5650 FVTWCHGLELTTLRYFVKIGKEQVCS-CGSRATTFNSHTQAYACWKHCLGFDFVYNPLLV 5708
Query 243 DVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDE 302
D+QQWG++GNLQ NHDL+C VHG+AHVAS DAIMTRCLA++ F + V+W + YP I +E
Sbjct 5709 DIQQWGYSGNLQFNHDLHCNVHGHAHVASVDAIMTRCLAINNAFCQDVNWDLTYPHIANE 5768
Query 303 LKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYK 362
++N++CR +Q M + A + A K V++DIGNPK IKCV + DV ++FYD P +
Sbjct 5769 DEVNSSCRYLQRMYLNACVDALKVNVVYDIGNPKGIKCVRRGDVNFRFYDKNPIVRNVKQ 5828
Query 363 IEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVN 422
E Y Y H DKF DG+C+FWNCNVD YP NS+VCR+DTR LS NLPGC+GGSLYVN
Sbjct 5829 FE---YDYNQHKDKFADGLCMFWNCNVDCYPDNSLVCRYDTRNLSVFNLPGCNGGSLYVN 5885
Query 423 KHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGA 482
KHAF+TP FD+ +F NLK +PFF+Y SPCE+ V+ D V L + CIT+CN+GGA
Sbjct 5886 KHAFYTPKFDRISFRNLKAMPFFFYDSSPCETIQVDGVAQ-DLVSLATKDCITKCNIGGA 5944
Query 483 VCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQ 527
VC+ HA Y ++ +YN ++AGF+ WV + + YNLW +F+ LQ
Sbjct 5945 VCKKHAQMYAEFVTSYNAAVTAGFTFWVTNKLNPYNLWKSFSALQ 5989
>sp|Q008X6|R1AB_WBV24 Replicase polyprotein 1ab OS=White bream
virus (isolate Blicca bjoerkna L./Germany/DF24/00) OX=766180
GN=rep PE=1 SV=1
Length=6872
Score = 117 bits (293), Expect = 4e-26, Method: Composition-based stats.
Identities = 37/110 (34%), Positives = 54/110 (49%), Gaps = 8/110 (7%)
Query 179 DRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYA--CWHHS---IGF 233
+RVV+VL+ G +L ++ +G + TC C + AT ++ + C HH+
Sbjct 6074 NRVVYVLYGAGNDLRALTNLNIVG-DYTCEKCTKEATFYTIHREIVHTFCNHHAPSQFPL 6132
Query 234 DYVYNPFMIDVQQWGFTG-NLQSNHDLYC-QVHGNAHVASCDAIMTRCLA 281
N ID+Q +L + H C Q HG+AH AS D IMT CLA
Sbjct 6133 MGTINAQAIDIQHASANKQSLTNTHAEVCNQQHGDAHTASADTIMTGCLA 6182
>sp|P0C6V8|R1AB_BRV1 Replicase polyprotein 1ab OS=Breda virus
1 OX=360393 GN=rep PE=2 SV=1
Length=6733
Score = 117 bits (293), Expect = 4e-26, Method: Composition-based stats.
Identities = 37/134 (28%), Positives = 60/134 (45%), Gaps = 21/134 (16%)
Query 183 FVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACW--HHSIGFDYVYNPF 240
F+L++ +L S+K++V+ G C C A C Y C + ++ + N
Sbjct 5953 FILYSCSNDLKSLKFYVEFGTNYFCS-CGELAICL-MRDGLYKCRNCYGNMSISKLVNCK 6010
Query 241 MIDVQQWGFTGNLQSNHDLYCQ-VHGNAHVASCDAIMTRC--LAVHEC------------ 285
+DVQ+ LQ HD CQ HG++H A CDA+MT+C LA ++
Sbjct 6011 YLDVQKERI--KLQDAHDAICQQFHGDSHEALCDAVMTKCLYLASYDAAFKDTIHVKYKD 6068
Query 286 FVKRVDWTIEYPII 299
+ + I P +
Sbjct 6069 LCLEIQYKITSPYV 6082
>sp|P0C6V7|R1AB_BEV Replicase polyprotein 1ab OS=Berne virus OX=11156
GN=rep PE=1 SV=1
Length=6857
Score = 112 bits (280), Expect = 2e-24, Method: Composition-based stats.
Identities = 33/101 (33%), Positives = 50/101 (50%), Gaps = 7/101 (7%)
Query 183 FVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACW--HHSIGFDYVYNPF 240
F+L++ +L S+K++V+ C C A C Y C + + + N
Sbjct 6077 FILYSCSNDLKSLKFYVEFDTCYFCS-CGEMAICL-MRDGNYKCRNCYGGMLISKLVNCK 6134
Query 241 MIDVQQWGFTGNLQSNHDLYCQ-VHGNAHVASCDAIMTRCL 280
+DVQ+ LQ HD CQ HG++H A CDA+MT+CL
Sbjct 6135 YLDVQKERV--KLQDAHDAICQQFHGDSHEALCDAVMTKCL 6173
>sp|P0C664|ZWILC_CAEBR Protein zwilch homolog OS=Caenorhabditis
briggsae OX=6238 GN=zwl-1 PE=3 SV=1
Length=639
Score = 34.2 bits (77), Expect = 4.0, Method: Composition-based stats.
Identities = 11/34 (32%), Positives = 21/34 (62%), Gaps = 0/34 (0%)
Query 162 VRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSM 195
+R +I+ SDTL+ SD + F+L +L+++
Sbjct 447 LRGRIINKFSDTLQFPSDELTFILKTCENDLSTL 480
Lambda K H a alpha
0.318 0.144 0.478 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0441 0.140 1.90 42.6 43.6
Effective search space used: 55109926840
Search has CONVERGED!
Database: uniprot_sprot.fasta
Posted date: Apr 3, 2024 12:05 PM
Number of letters in database: 206,678,396
Number of sequences in database: 571,282
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40