Contact Molecules for Homologous Proteins


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PID QueryLength Homolgous Sequence in PDB UniProt Query TITLE
1682730 498 69 Q13568(IRF5_HUMAN) RecName: Full=Interferon regulatory factor 5 ; Short=IRF-5 ;
QUERYSEQ
MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGDNTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEVCSNGPAPTDSQPPEDYSFGAGEEEEEEEEL
QRMLPSLSLTEDVKWPPTLQPPTLRPPTLQPPTLQPPVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQLLPDLLISPHMLPLTDLEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQEQVELFGPISLEQVRFP
SPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWPDRKPREKKLITVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDL
KDRMVEQFKELHHIWQSQQRLQPVAQAPPGAGLGVGQGPWPMHPAGMQ
[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]

UniProt Feature Tables [Q13568(IRF5_HUMAN)]

498
region name description
1-498 CHAIN /note="Interferon regulatory factor 5" /id="PRO_0000154558"
14-122 DNA_BIND /note="IRF tryptophan pentad repeat"
121-207 REGION /note="Disordered"
478-498 REGION /note="Disordered"
169-206 COMPBIAS /note="Pro residues"
1-498 DISORDER predicted by DISOPRED

MONOMER
498
pdb_id a1 identity[%]2 description
3dsh A 99.6 IRF5_HUMAN Interferon regulatory factor 5
7rh2 A 46.2 Q99419_HUMAN ICSAT transcription factor
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue.
HETERO
498 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1t2k[1] F ATF2_HUMAN Cyclic-AMP-dependent transcription factor ATF-2[61.. C 33.3
/44.3
3
/3
IRF3_HUMAN Interferon regulatory factor 3
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
NUCLEOTIDE
498 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
8jkl[8] C GATA-Forward E 70.0
/48.0
10
/10
F2Z3D5_HUMAN Interferon regulatory factor 4
8jkl[8] D GATA-Reverse E 66.7
/48.0
9
/11
F2Z3D5_HUMAN Interferon regulatory factor 4
7jm4[8] A Interferon-Stimulated Response Elements C 70.0
/45.3
10
/10
IRF4_HUMAN Interferon regulatory factor 4
7jm4[6] B Interferon-Stimulated Response Elements C 55.6
/45.3
9
/9
IRF4_HUMAN Interferon regulatory factor 4
7rh2[2] F DNA (5'-D(*GP*CP*TP*TP*TP*CP*TP*CP*GP*GP*TP*TP*TP*.. G 70.0
/46.2
10
/11
Q99419_HUMAN ICSAT transcription factor
7o56[3] B DNA (5'-D(P*AP*AP*TP*AP*AP*AP*AP*GP*AP*AP*AP*CP*CP.. A 77.8
/45.0
9
/9
IRF4_HUMAN Interferon regulatory factor 4
7o56[2] C DNA (5'-D(P*TP*TP*TP*AP*CP*TP*TP*TP*CP*GP*GP*TP*TP.. A 58.3
/45.0
12
/13
IRF4_HUMAN Interferon regulatory factor 4
8jkn[4] A GAAA-Forward C 80.0
/45.3
10
/10
F2Z3D5_HUMAN Interferon regulatory factor 4
8jkn[4] B GAAA-Reverse C 50.0
/45.3
10
/12
F2Z3D5_HUMAN Interferon regulatory factor 4
8jkq[4] A GACA-Forward C 77.8
/44.8
9
/9
F2Z3D5_HUMAN Interferon regulatory factor 4
8jkq[4] B GACA-Reverse C 54.5
/44.8
11
/12
F2Z3D5_HUMAN Interferon regulatory factor 4
8jks[4] A GAGA-Forward C 75.0
/45.3
8
/8
F2Z3D5_HUMAN Interferon regulatory factor 4
8jks[4] B GAGA-Reverse C 54.5
/45.3
11
/13
F2Z3D5_HUMAN Interferon regulatory factor 4
2o61[1] A 36-MER C 45.5
/45.1
11
/34
TF65_HUMAN IRF7_HUMAN IRF3_HUMAN Transcription factor p65/Interferon regulatory fac..
2o61[1] B 34-MER C 38.5
/45.1
13
/36
TF65_HUMAN IRF7_HUMAN IRF3_HUMAN Transcription factor p65/Interferon regulatory fac..
2pi0[4] A PRDIII-I region of human interferon-B promoter str.. C 50.0
/46.9
12
/12
IRF3_HUMAN Interferon regulatory factor 3
2pi0[4] B PRDIII-I region of human interferon-B promoter str.. C 54.5
/46.9
11
/13
IRF3_HUMAN Interferon regulatory factor 3
7ogs[4] C DNA (5'-D(P*TP*GP*TP*AP*CP*TP*TP*TP*CP*GP*GP*TP*TP.. A 63.6
/45.0
11
/13
IRF4_HUMAN Interferon regulatory factor 4
7ogs[4] D DNA (5'-D(P*AP*TP*AP*AP*CP*TP*GP*AP*AP*AP*CP*CP*GP.. A 75.0
/45.0
12
/12
IRF4_HUMAN Interferon regulatory factor 4
7oot[2] C DNA (5'-D(P*TP*CP*AP*AP*CP*TP*GP*AP*AP*AP*CP*CP*GP.. A 81.8
/45.0
11
/11
IRF4_HUMAN Interferon regulatory factor 4
7oot[2] D DNA (5'-D(P*AP*GP*CP*TP*TP*TP*CP*TP*CP*GP*GP*TP*TP.. A 41.7
/45.0
12
/13
IRF4_HUMAN Interferon regulatory factor 4
1t2k[2] A 31-MER C 55.6
/44.3
9
/9
IRF3_HUMAN Interferon regulatory factor 3
1t2k[2] B 31-MER C 46.7
/44.3
15
/17
IRF3_HUMAN Interferon regulatory factor 3
2o6g[4] A interferon-b enhancer C 50.0
/44.3
12
/12
IRF3_HUMAN Interferon regulatory factor 3
2o6g[4] B interferon-b enhancer C 42.9
/44.3
14
/16
IRF3_HUMAN Interferon regulatory factor 3
2irf[4] F DNA (5'-D(*TP*TP*CP*AP*CP*TP*TP*TP*CP*AP*CP*(5IU)P.. G 70.0
/43.9
10
/10
IRF2_MOUSE INTERFERON REGULATORY FACTOR 2
2irf[3] A DNA (5'-D(P*AP*AP*GP*TP*GP*AP*AP*AP*GP*(5IU)P*GP*A.. H 63.6
/43.9
11
/11
IRF2_MOUSE INTERFERON REGULATORY FACTOR 2
2irf[2] E DNA (5'-D(*TP*TP*CP*AP*CP*TP*TP*TP*CP*AP*CP*(5IU)P.. I 70.0
/43.9
10
/10
IRF2_MOUSE INTERFERON REGULATORY FACTOR 2
1if1[2] A DNA (26-MER) C 68.2
/42.9
22
/22
IRF1_MOUSE PROTEIN (INTERFERON REGULATORY FACTOR 1)
1if1[2] B DNA (26-MER) C 50.0
/42.9
2
/2
IRF1_MOUSE PROTEIN (INTERFERON REGULATORY FACTOR 1)
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
METAL
498 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
3qu3[3] D NA
SODIUM ION[1 atoms]
A 50.0
/41.5
4
/4
IRF7_MOUSE Interferon regulatory factor 7
3qu6[1] K NA
SODIUM ION[1 atoms]
A 50.0
/45.8
2
/2
Q7Z5G6_HUMAN IRF3 protein
3qu6[2] L NA
SODIUM ION[1 atoms]
A 40.0
/45.8
5
/5
Q7Z5G6_HUMAN IRF3 protein
3qu6[2] D ZN
ZINC ION[1 atoms]
A 0.0
/45.8
2
/2
Q7Z5G6_HUMAN IRF3 protein
3qu6[1] E ZN
ZINC ION[1 atoms]
A 50.0
/45.8
2
/2
Q7Z5G6_HUMAN IRF3 protein
3qu6[2] F ZN
ZINC ION[1 atoms]
A 50.0
/45.8
2
/2
Q7Z5G6_HUMAN IRF3 protein
3qu6[4] G ZN
ZINC ION[1 atoms]
A 25.0
/45.8
4
/4
Q7Z5G6_HUMAN IRF3 protein
3qu6[4] H CL
CHLORIDE ION[1 atoms]
A 25.0
/45.8
4
/4
Q7Z5G6_HUMAN IRF3 protein
3qu6[1] I CL
CHLORIDE ION[1 atoms]
A 0.0
/45.8
1
/1
Q7Z5G6_HUMAN IRF3 protein
3qu6[2] M CL
CHLORIDE ION[1 atoms]
A 25.0
/45.8
4
/4
Q7Z5G6_HUMAN IRF3 protein
5bvi[2] C CL
CHLORIDE ION[1 atoms]
A 66.7
/42.1
6
/6
Q5SUZ4_MOUSE Interferon regulatory factor 4
5bvi[1] D CL
CHLORIDE ION[1 atoms]
A 16.7
/42.1
6
/6
Q5SUZ4_MOUSE Interferon regulatory factor 4
5bvi[1] E CL
CHLORIDE ION[1 atoms]
A 50.0
/42.1
2
/2
Q5SUZ4_MOUSE Interferon regulatory factor 4
6td4[1] B CL
CHLORIDE ION[1 atoms]
A 0.0
/44.7
1
/1
IRF4_HUMAN Interferon regulatory factor 4
2irf[6] M K
POTASSIUM ION[1 atoms]
G 25.0
/43.9
4
/4
IRF2_MOUSE INTERFERON REGULATORY FACTOR 2
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
HOMO
498 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
3dsh[2] A IRF5_HUMAN Interferon regulatory factor 5[236 aa] A 98.4
/99.6
62
/62
IRF5_HUMAN Interferon regulatory factor 5
7o56[1] E IRF4_HUMAN Interferon regulatory factor 4[112 aa] D 50.0
/45.3
2
/2
IRF4_HUMAN Interferon regulatory factor 4
7o56[1] D IRF4_HUMAN Interferon regulatory factor 4[109 aa] E 0.0
/45.3
2
/2
IRF4_HUMAN Interferon regulatory factor 4
2o6g[3] E IRF3_HUMAN Interferon regulatory factor 3[110 aa] C 66.7
/44.3
3
/3
IRF3_HUMAN Interferon regulatory factor 3
2o6g[2] C IRF3_HUMAN Interferon regulatory factor 3[110 aa] E 0.0
/44.3
3
/3
IRF3_HUMAN Interferon regulatory factor 3
2pi0[1] C IRF3_HUMAN Interferon regulatory factor 3[98 aa] E 0.0
/45.2
1
/1
IRF3_HUMAN Interferon regulatory factor 3
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
PRECIPITANT
498 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
7oot[1] E PO4
PHOSPHATE ION[5 atoms]
B 0.0
/45.0
2
/2
IRF4_HUMAN Interferon regulatory factor 4
3qu3[1] F EDO
1,2-ETHANEDIOL[4 atoms]
B 50.0
/41.9
2
/2
IRF7_MOUSE Interferon regulatory factor 7
3qu3[2] G EDO
1,2-ETHANEDIOL[4 atoms]
B 33.3
/41.9
3
/3
IRF7_MOUSE Interferon regulatory factor 7
3qu3[1] J EDO
1,2-ETHANEDIOL[4 atoms]
C 66.7
/41.5
3
/5
IRF7_MOUSE Interferon regulatory factor 7
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.