Contact Molecules for Homologous Proteins

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PID QueryLength Homolgous Sequence in PDB UniProt Query TITLE
6445 675 24 Q8N3R9(PALS1_HUMAN) RecName: Full=Protein PALS1 ;AltName: Full=MAGUK p55 subfamily member 5;AltName: Full=Membrane protein, palmitoylated 5 ;AltName: Full=Protein associated with Lin-7 1 ;
QUERYSEQ 
MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIRQQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLL
LQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE
VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLY
NANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP
SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWLR
[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]

UniProt Feature Tables [Q8N3R9(PALS1_HUMAN)]

675
region name description
1-675 CHAIN /note="Protein PALS1" /id="PRO_0000094580"
120-177 DOMAIN /note="L27 1"
179-235 DOMAIN /note="L27 2"
256-336 DOMAIN /note="PDZ"
345-417 DOMAIN /note="SH3"
479-660 DOMAIN /note="Guanylate kinase-like"
1-345 REGION /note="Required for the correct localization of PALS1 and PATJ at cell-cell contacts and the normal formation of tight junctions and adherens junctions"
1-34 REGION /note="Disordered"
21-140 REGION /note="Interaction with PARD6B"
51-78 REGION /note="Disordered"
181-243 REGION /note="Interaction with LIN7C"
10-34 COMPBIAS /note="Basic and acidic residues"
57-78 COMPBIAS /note="Basic and acidic residues"
486-493 BINDING /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616"
1-469 DISORDER predicted by DISOPRED

MONOMER
675
pdb_id a1 identity[%]2 description
4wsi A 100.0 MPP5_HUMAN MPP5_HUMAN MAGUK p55 subfamily member 5
7m4r A 100.0 MPP5_HUMAN MPP5_HUMAN MAGUK p55 subfamily member 5
4wsi B 100.0 MPP5_HUMAN MPP5_HUMAN MAGUK p55 subfamily member 5
7m4r B 100.0 MPP5_HUMAN MPP5_HUMAN MAGUK p55 subfamily member 5
3uit D 100.0 INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, Protein lin-7 homolog B
3uit A 100.0 INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, Protein lin-7 homolog B
3uit B 100.0 INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, Protein lin-7 homolog B
3uit C 100.0 INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, Protein lin-7 homolog B
1va8 A 99.0 MPP5_MOUSE MAGUK p55 subfamily member 5
7qcs B 100.0 PALS1_HUMAN Protein PALS1
7qcs A 100.0 PALS1_HUMAN Protein PALS1
4uu5 A 100.0 MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5
4uu6 A 100.0 MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5
7qcs E 100.0 PALS1_HUMAN Protein PALS1
7ntk F 100.0 MPP5_HUMAN MAGUK p55 subfamily member 5
7ntk D 100.0 MPP5_HUMAN MAGUK p55 subfamily member 5
7ntk A 100.0 MPP5_HUMAN MAGUK p55 subfamily member 5
7ntj A 100.0 MPP5_HUMAN MAGUK p55 subfamily member 5
7ntj C 100.0 MPP5_HUMAN MAGUK p55 subfamily member 5
7ntk B 100.0 MPP5_HUMAN MAGUK p55 subfamily member 5
1y76 D 100.0 MPP5_HUMAN MAGUK p55 subfamily member 5
1y76 B 100.0 MPP5_HUMAN MAGUK p55 subfamily member 5
1vf6 D 91.7 MPP5_MOUSE MAGUK p55 subfamily member 5
1vf6 C 91.7 MPP5_MOUSE MAGUK p55 subfamily member 5 
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue.
HETERO
675 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1y76 A MPDZ_RAT protein associated to tight junctions[62 aa] B 100.0
/100.0		 4
/4		 MPP5_HUMAN MAGUK p55 subfamily member 5
1y76 C MPDZ_RAT protein associated to tight junctions[62 aa] B 100.0
/100.0		 26
/26		 MPP5_HUMAN MAGUK p55 subfamily member 5
1y76 A MPDZ_RAT protein associated to tight junctions[62 aa] D 100.0
/100.0		 27
/27		 MPP5_HUMAN MAGUK p55 subfamily member 5
1y76 C MPDZ_RAT protein associated to tight junctions[62 aa] D 100.0
/100.0		 3
/3		 MPP5_HUMAN MAGUK p55 subfamily member 5
4uu5 B CRUM1_HUMAN PROTEIN CRUMBS HOMOLOG 1[14 aa] A 100.0
/100.0		 13
/13		 MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5
4wsi C CRB_DROME Protein crumbs[18 aa] A 100.0
/100.0		 37
/37		 MPP5_HUMAN MPP5_HUMAN MAGUK p55 subfamily member 5
4wsi D CRB_DROME Protein crumbs[18 aa] B 100.0
/100.0		 35
/35		 MPP5_HUMAN MPP5_HUMAN MAGUK p55 subfamily member 5
7m4r C VEMP_SARS2 Envelope small membrane protein[9 aa] A 100.0
/100.0		 11
/11		 MPP5_HUMAN MPP5_HUMAN MAGUK p55 subfamily member 5
7ntj B VEMP_SARS Envelope small membrane protein[4 aa] A 100.0
/100.0		 13
/13		 MPP5_HUMAN MAGUK p55 subfamily member 5
7ntj D VEMP_SARS Envelope small membrane protein[7 aa] C 100.0
/100.0		 13
/13		 MPP5_HUMAN MAGUK p55 subfamily member 5
7ntk C VEMP_SARS2 Envelope small membrane protein[7 aa] A 100.0
/100.0		 12
/12		 MPP5_HUMAN MAGUK p55 subfamily member 5
7ntk G VEMP_SARS2 Envelope small membrane protein[7 aa] B 100.0
/100.0		 14
/14		 MPP5_HUMAN MAGUK p55 subfamily member 5
7ntk E VEMP_SARS2 Envelope small membrane protein[7 aa] D 100.0
/100.0		 14
/14		 MPP5_HUMAN MAGUK p55 subfamily member 5
7ntk H VEMP_SARS2 Envelope small membrane protein[6 aa] F 100.0
/100.0		 14
/14		 MPP5_HUMAN MAGUK p55 subfamily member 5
7qcs C VEMP_SARS2 Envelope small membrane protein[5 aa] A 100.0
/100.0		 14
/14		 PALS1_HUMAN Protein PALS1
7qcs D VEMP_SARS2 Envelope small membrane protein[5 aa] B 100.0
/100.0		 12
/12		 PALS1_HUMAN Protein PALS1
1vf6 A INADL_HUMAN PALS1-associated tight junction protein[58 aa] C 100.0
/91.7		 20
/20		 MPP5_MOUSE MAGUK p55 subfamily member 5
1vf6 A INADL_HUMAN PALS1-associated tight junction protein[58 aa] C 100.0
/91.7		 20
/20		 MPP5_MOUSE MAGUK p55 subfamily member 5
1vf6 B INADL_HUMAN PALS1-associated tight junction protein[60 aa] C 50.0
/91.7		 2
/2		 MPP5_MOUSE MAGUK p55 subfamily member 5
1vf6 B INADL_HUMAN PALS1-associated tight junction protein[60 aa] C 50.0
/91.7		 2
/2		 MPP5_MOUSE MAGUK p55 subfamily member 5
1vf6 A INADL_HUMAN PALS1-associated tight junction protein[58 aa] D 0.0
/91.7		 1
/1		 MPP5_MOUSE MAGUK p55 subfamily member 5
1vf6 A INADL_HUMAN PALS1-associated tight junction protein[58 aa] D 0.0
/91.7		 1
/1		 MPP5_MOUSE MAGUK p55 subfamily member 5
1vf6 B INADL_HUMAN PALS1-associated tight junction protein[60 aa] D 100.0
/91.7		 19
/19		 MPP5_MOUSE MAGUK p55 subfamily member 5
1vf6 B INADL_HUMAN PALS1-associated tight junction protein[60 aa] D 100.0
/91.7		 19
/19		 MPP5_MOUSE MAGUK p55 subfamily member 5
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
COMPOUND
675 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
4uu5 K PUN
2,2,4,4,6,6,8-heptamethylnonane[16 atoms] 		A 100.0
/100.0		 2
/2		 MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
METAL
675 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
4uu5 F CL
CHLORIDE ION[1 atoms] 		A 100.0
/100.0		 1
/1		 MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5
4uu5 G CL
CHLORIDE ION[1 atoms] 		A 100.0
/100.0		 2
/2		 MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5
4uu5 H CL
CHLORIDE ION[1 atoms] 		A 100.0
/100.0		 2
/2		 MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5
4uu5 I CL
CHLORIDE ION[1 atoms] 		A 100.0
/100.0		 1
/1		 MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5
4uu5 L CL
CHLORIDE ION[1 atoms] 		A 100.0
/100.0		 1
/1		 MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5
4uu6 C CL
CHLORIDE ION[1 atoms] 		A 100.0
/100.0		 1
/1		 MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5
4uu5 J NA
SODIUM ION[1 atoms] 		A 100.0
/100.0		 3
/3		 MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
HOMO
675 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1y76 D MPP5_HUMAN MAGUK p55 subfamily member 5[60 aa] B 100.0
/100.0		 6
/6		 MPP5_HUMAN MAGUK p55 subfamily member 5
1y76 B MPP5_HUMAN MAGUK p55 subfamily member 5[60 aa] D 100.0
/100.0		 6
/6		 MPP5_HUMAN MAGUK p55 subfamily member 5
7m4r B MPP5_HUMAN MPP5_HUMAN MAGUK p55 subfamily member 5[270 aa] A 100.0
/100.0		 20
/20		 MPP5_HUMAN MPP5_HUMAN MAGUK p55 subfamily member 5
7m4r A MPP5_HUMAN MPP5_HUMAN MAGUK p55 subfamily member 5[360 aa] B 100.0
/100.0		 19
/19		 MPP5_HUMAN MPP5_HUMAN MAGUK p55 subfamily member 5
7qcs B PALS1_HUMAN Protein PALS1[98 aa] A 100.0
/100.0		 9
/9		 PALS1_HUMAN Protein PALS1
7qcs E PALS1_HUMAN Protein PALS1[82 aa] A 100.0
/100.0		 2
/2		 PALS1_HUMAN Protein PALS1
7qcs A PALS1_HUMAN Protein PALS1[97 aa] B 100.0
/100.0		 9
/9		 PALS1_HUMAN Protein PALS1
7qcs A PALS1_HUMAN Protein PALS1[97 aa] E 100.0
/100.0		 1
/1		 PALS1_HUMAN Protein PALS1
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
PRECIPITANT
675 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
3uit E ACT
ACETATE ION[4 atoms] 		A 100.0
/100.0		 2
/3		 INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, P..
3uit G ACT
ACETATE ION[4 atoms] 		A 100.0
/100.0		 1
/2		 INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, P..
3uit H ACT
ACETATE ION[4 atoms] 		A 100.0
/100.0		 2
/5		 INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, P..
3uit J ACT
ACETATE ION[4 atoms] 		A 100.0
/100.0		 3
/3		 INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, P..
3uit K ACT
ACETATE ION[4 atoms] 		A 100.0
/100.0		 1
/5		 INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, P..
3uit M ACT
ACETATE ION[4 atoms] 		B 100.0
/100.0		 2
/3		 INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, P..
3uit O ACT
ACETATE ION[4 atoms] 		B 100.0
/100.0		 1
/3		 INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, P..
3uit P ACT
ACETATE ION[4 atoms] 		B 100.0
/100.0		 1
/2		 INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, P..
3uit S ACT
ACETATE ION[4 atoms] 		C 100.0
/100.0		 1
/2		 INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, P..
3uit U ACT
ACETATE ION[4 atoms] 		D 100.0
/100.0		 1
/2		 INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, P..
3uit V ACT
ACETATE ION[4 atoms] 		D 100.0
/100.0		 2
/5		 INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, P..
3uit W ACT
ACETATE ION[4 atoms] 		D 100.0
/100.0		 3
/3		 INADL_MOUSE MPP5_HUMAN LIN7B_RAT InaD-like protein, MAGUK p55 subfamily member 5, P..
4uu6 D ACT
ACETATE ION[4 atoms] 		A 100.0
/100.0		 1
/1		 MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5
4uu6 B GOL
GLYCEROL[6 atoms] 		A 100.0
/100.0		 6
/6		 MPP5_HUMAN MAGUK P55 SUBFAMILY MEMBER 5
7ntk I FLC
CITRATE ANION[13 atoms] 		B 100.0
/100.0		 2
/2		 MPP5_HUMAN MAGUK p55 subfamily member 5
7ntk J EDO
1,2-ETHANEDIOL[4 atoms] 		B 100.0
/100.0		 1
/2		 MPP5_HUMAN MAGUK p55 subfamily member 5
7ntk K EDO
1,2-ETHANEDIOL[4 atoms] 		B 100.0
/100.0		 1
/1		 MPP5_HUMAN MAGUK p55 subfamily member 5
7ntk M EDO
1,2-ETHANEDIOL[4 atoms] 		D 100.0
/100.0		 5
/5		 MPP5_HUMAN MAGUK p55 subfamily member 5
7ntk N EDO
1,2-ETHANEDIOL[4 atoms] 		F 100.0
/100.0		 2
/2		 MPP5_HUMAN MAGUK p55 subfamily member 5
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.