PSIBLAST 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Stephen F.
Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005)
"Protein database searches using compositionally adjusted
substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: uniprot_sprot.fasta
571,282 sequences; 206,678,396 total letters
Results from round 1
Query= sp|Q8N3R9|PALS1_HUMAN Protein PALS1 OS=Homo sapiens OX=9606 GN=PALS1
PE=1 SV=3
Length=675
Score E
Sequences producing significant alignments: (Bits) Value
sp|Q8N3R9|PALS1_HUMAN Protein PALS1 OS=Homo sapiens OX=9606 GN=PA... 1398 0.0
sp|Q5RDQ2|PALS1_PONAB Protein PALS1 OS=Pongo abelii OX=9601 GN=PA... 1393 0.0
sp|E2QY99|PALS1_CANLF Protein PALS1 OS=Canis lupus familiaris OX=... 1383 0.0
sp|B4F7E7|PALS1_RAT Protein PALS1 OS=Rattus norvegicus OX=10116 G... 1362 0.0
sp|Q9JLB2|PALS1_MOUSE Protein PALS1 OS=Mus musculus OX=10090 GN=P... 1361 0.0
sp|Q8JHF4|PAL1A_DANRE Protein PALS1 OS=Danio rerio OX=7955 GN=pal... 1009 0.0
sp|Q8BVD5|MPP7_MOUSE MAGUK p55 subfamily member 7 OS=Mus musculus... 394 3e-128
sp|A8KBF6|MPP7_XENTR MAGUK p55 subfamily member 7 OS=Xenopus trop... 392 2e-127
sp|Q6P0D7|MPP7_DANRE MAGUK p55 subfamily member 7 OS=Danio rerio ... 383 6e-124
sp|Q5U2Y3|MPP7_RAT MAGUK p55 subfamily member 7 OS=Rattus norvegi... 370 6e-119
sp|Q5T2T1|MPP7_HUMAN MAGUK p55 subfamily member 7 OS=Homo sapiens... 370 7e-119
sp|A6QQZ7|MPP7_BOVIN MAGUK p55 subfamily member 7 OS=Bos taurus O... 369 1e-118
sp|Q13368|MPP3_HUMAN MAGUK p55 subfamily member 3 OS=Homo sapiens... 353 3e-112
sp|Q9JLB0|PALS2_MOUSE Protein PALS2 OS=Mus musculus OX=10090 GN=P... 351 6e-112
sp|O88954|MPP3_RAT MAGUK p55 subfamily member 3 OS=Rattus norvegi... 350 4e-111
sp|D3ZAA9|MPP2_RAT MAGUK p55 subfamily member 2 OS=Rattus norvegi... 346 3e-110
sp|Q14168|MPP2_HUMAN MAGUK p55 subfamily member 2 OS=Homo sapiens... 347 4e-110
sp|Q9WV34|MPP2_MOUSE MAGUK p55 subfamily member 2 OS=Mus musculus... 345 9e-110
sp|Q9NZW5|PALS2_HUMAN Protein PALS2 OS=Homo sapiens OX=9606 GN=PA... 338 2e-107
sp|O88910|MPP3_MOUSE MAGUK p55 subfamily member 3 OS=Mus musculus... 332 3e-104
sp|Q24210|CSKP_DROME Peripheral plasma membrane protein CASK OS=D... 303 2e-90
sp|Q9QYH1|MPP4_RAT MAGUK p55 subfamily member 4 OS=Rattus norvegi... 285 3e-88
sp|O70589|CSKP_MOUSE Peripheral plasma membrane protein CASK OS=M... 284 7e-83
sp|O14936|CSKP_HUMAN Peripheral plasma membrane protein CASK OS=H... 283 1e-82
sp|Q62915|CSKP_RAT Peripheral plasma membrane protein CASK OS=Rat... 279 2e-81
sp|Q00013|EM55_HUMAN 55 kDa erythrocyte membrane protein OS=Homo ... 264 1e-79
sp|A9CB74|EM55_PAPAN 55 kDa erythrocyte membrane protein OS=Papio... 263 3e-79
sp|Q5RDW4|EM55_PONAB 55 kDa erythrocyte membrane protein OS=Pongo... 263 3e-79
sp|P70290|EM55_MOUSE 55 kDa erythrocyte membrane protein OS=Mus m... 262 7e-79
sp|Q17QN6|EM55_BOVIN 55 kDa erythrocyte membrane protein OS=Bos t... 259 6e-78
sp|P54936|LIN2_CAEEL Protein lin-2 OS=Caenorhabditis elegans OX=6... 271 7e-78
sp|Q5ZJ00|EM55_CHICK 55 kDa erythrocyte membrane protein OS=Gallu... 259 1e-77
sp|P49697|EM55_TAKRU 55 kDa erythrocyte membrane protein OS=Takif... 255 3e-76
sp|Q15700|DLG2_HUMAN Disks large homolog 2 OS=Homo sapiens OX=960... 212 3e-57
sp|Q91XM9|DLG2_MOUSE Disks large homolog 2 OS=Mus musculus OX=100... 203 2e-54
sp|Q63622|DLG2_RAT Disks large homolog 2 OS=Rattus norvegicus OX=... 202 3e-54
sp|Q12959|DLG1_HUMAN Disks large homolog 1 OS=Homo sapiens OX=960... 197 3e-52
sp|Q62936|DLG3_RAT Disks large homolog 3 OS=Rattus norvegicus OX=... 196 7e-52
sp|P70175|DLG3_MOUSE Disks large homolog 3 OS=Mus musculus OX=100... 196 7e-52
sp|Q92796|DLG3_HUMAN Disks large homolog 3 OS=Homo sapiens OX=960... 194 2e-51
sp|Q811D0|DLG1_MOUSE Disks large homolog 1 OS=Mus musculus OX=100... 194 6e-51
sp|Q5PYH7|DLG2_DANRE Disks large homolog 2 OS=Danio rerio OX=7955... 193 9e-51
sp|Q5PYH5|DLG1L_DANRE Discs large homolog 1-like protein OS=Danio... 191 2e-50
sp|Q62696|DLG1_RAT Disks large homolog 1 OS=Rattus norvegicus OX=... 189 2e-49
sp|P78352|DLG4_HUMAN Disks large homolog 4 OS=Homo sapiens OX=960... 187 2e-49
sp|Q62108|DLG4_MOUSE Disks large homolog 4 OS=Mus musculus OX=100... 187 3e-49
sp|P31016|DLG4_RAT Disks large homolog 4 OS=Rattus norvegicus OX=... 186 4e-49
sp|Q28C55|DLG1_XENTR Disks large homolog 1 OS=Xenopus tropicalis ... 187 1e-48
sp|Q6P7F1|MPP4_MOUSE MAGUK p55 subfamily member 4 OS=Mus musculus... 181 2e-47
sp|P31007|DLG1_DROME Disks large 1 tumor suppressor protein OS=Dr... 182 5e-47
sp|Q96JB8|MPP4_HUMAN MAGUK p55 subfamily member 4 OS=Homo sapiens... 177 4e-46
sp|G5ECY0|DLG1_CAEEL Disks large homolog 1 OS=Caenorhabditis eleg... 175 1e-44
sp|Q6R005|DLG4_DANRE Disks large homolog 4 OS=Danio rerio OX=7955... 163 9e-41
sp|Q64520|KGUA_MOUSE Guanylate kinase OS=Mus musculus OX=10090 GN... 135 2e-35
sp|P46195|KGUA_BOVIN Guanylate kinase OS=Bos taurus OX=9913 GN=GU... 133 2e-34
sp|P31006|KGUA_PIG Guanylate kinase OS=Sus scrofa OX=9823 GN=GUK1... 132 3e-34
sp|Q16774|KGUA_HUMAN Guanylate kinase OS=Homo sapiens OX=9606 GN=... 131 7e-34
sp|Q2QPW1|GMK1_ORYSJ Guanylate kinase 1 OS=Oryza sativa subsp. ja... 129 3e-31
sp|Q5PYH6|DLG1_DANRE Disks large homolog 1 OS=Danio rerio OX=7955... 133 7e-31
sp|P15454|KGUA_YEAST Guanylate kinase OS=Saccharomyces cerevisiae... 120 4e-30
sp|P93757|GMK1_ARATH Guanylate kinase 1 OS=Arabidopsis thaliana O... 118 2e-27
sp|Q9P6I5|KGUA_SCHPO Guanylate kinase OS=Schizosaccharomyces pomb... 112 5e-27
sp|Q9M682|GMK2_ARATH Guanylate kinase 2 OS=Arabidopsis thaliana O... 113 8e-26
sp|Q54XF2|KGUA_DICDI Guanylate kinase OS=Dictyostelium discoideum... 104 2e-24
sp|Q72DM9|KGUA_DESVH Guanylate kinase OS=Desulfovibrio vulgaris (... 104 3e-24
sp|Q1WUB5|KGUA_LIGS1 Guanylate kinase OS=Ligilactobacillus saliva... 103 8e-24
sp|Q30XT1|KGUA_OLEA2 Guanylate kinase OS=Oleidesulfovibrio alaske... 101 3e-23
sp|Q3MD38|KGUA_TRIV2 Guanylate kinase OS=Trichormus variabilis (s... 99.8 1e-22
sp|Q8Z0I7|KGUA_NOSS1 Guanylate kinase OS=Nostoc sp. (strain PCC 7... 98.6 2e-22
sp|Q8NX22|KGUA_STAAW Guanylate kinase OS=Staphylococcus aureus (s... 99.0 3e-22
sp|Q6GA04|KGUA_STAAS Guanylate kinase OS=Staphylococcus aureus (s... 99.0 3e-22
sp|Q5HGM3|KGUA_STAAC Guanylate kinase OS=Staphylococcus aureus (s... 99.0 3e-22
sp|Q2G1U0|KGUA_STAA8 Guanylate kinase OS=Staphylococcus aureus (s... 99.0 3e-22
sp|Q2FHM9|KGUA_STAA3 Guanylate kinase OS=Staphylococcus aureus (s... 99.0 3e-22
sp|Q82ZD5|KGUA_ENTFA Guanylate kinase OS=Enterococcus faecalis (s... 98.6 3e-22
sp|Q8DMQ7|KGUA_THEVB Guanylate kinase OS=Thermosynechococcus vest... 97.4 5e-22
sp|P99176|KGUA_STAAN Guanylate kinase OS=Staphylococcus aureus (s... 97.8 6e-22
sp|P65219|KGUA_STAAM Guanylate kinase OS=Staphylococcus aureus (s... 97.8 6e-22
sp|Q6GHM6|KGUA_STAAR Guanylate kinase OS=Staphylococcus aureus (s... 97.8 7e-22
sp|Q2YXF9|KGUA_STAAB Guanylate kinase OS=Staphylococcus aureus (s... 97.8 7e-22
sp|Q38XU0|KGUA_LATSS Guanylate kinase OS=Latilactobacillus sakei ... 97.1 9e-22
sp|Q1GH67|KGUA_RUEST Guanylate kinase OS=Ruegeria sp. (strain TM1... 97.4 1e-21
sp|O34328|KGUA_BACSU Guanylate kinase OS=Bacillus subtilis (strai... 96.7 1e-21
sp|Q3SLI4|KGUA_THIDA Guanylate kinase OS=Thiobacillus denitrifica... 96.7 2e-21
sp|Q88C87|KGUA_PSEPK Guanylate kinase OS=Pseudomonas putida (stra... 95.9 3e-21
sp|P60549|KGUA_BDEBA Guanylate kinase OS=Bdellovibrio bacteriovor... 95.1 3e-21
sp|Q5F775|KGUA_NEIG1 Guanylate kinase OS=Neisseria gonorrhoeae (s... 94.7 7e-21
sp|Q01230|A57_VACCW Guanylate kinase homolog OS=Vaccinia virus (s... 92.8 7e-21
sp|Q5SI18|KGUA_THET8 Guanylate kinase OS=Thermus thermophilus (st... 95.1 8e-21
sp|Q72ID5|KGUA_THET2 Guanylate kinase OS=Thermus thermophilus (st... 94.7 9e-21
sp|Q0TPK6|KGUA_CLOP1 Guanylate kinase OS=Clostridium perfringens ... 94.0 2e-20
sp|P21074|A57_VACCC Guanylate kinase homolog OS=Vaccinia virus (s... 91.7 2e-20
sp|Q0SS73|KGUA_CLOPS Guanylate kinase OS=Clostridium perfringens ... 93.6 2e-20
sp|Q49WZ1|KGUA_STAS1 Guanylate kinase OS=Staphylococcus saprophyt... 93.2 2e-20
sp|Q8XJK8|KGUA_CLOPE Guanylate kinase OS=Clostridium perfringens ... 93.2 3e-20
sp|Q166A7|KGUA_ROSDO Guanylate kinase OS=Roseobacter denitrifican... 92.0 6e-20
sp|Q3AWM1|KGUA_SYNS9 Guanylate kinase OS=Synechococcus sp. (strai... 91.3 7e-20
sp|Q4L5R1|KGUA_STAHJ Guanylate kinase OS=Staphylococcus haemolyti... 91.7 8e-20
sp|P65221|KGUA_STRA5 Guanylate kinase OS=Streptococcus agalactiae... 91.7 9e-20
sp|P65220|KGUA_STRA3 Guanylate kinase OS=Streptococcus agalactiae... 91.7 9e-20
sp|Q3K368|KGUA_STRA1 Guanylate kinase OS=Streptococcus agalactiae... 91.7 9e-20
sp|Q5LS25|KGUA_RUEPO Guanylate kinase OS=Ruegeria pomeroyi (strai... 91.7 1e-19
sp|Q1AVZ3|KGUA_RUBXD Guanylate kinase OS=Rubrobacter xylanophilus... 90.1 2e-19
sp|Q9CEE3|KGUA_LACLA Guanylate kinase OS=Lactococcus lactis subsp... 90.1 3e-19
sp|Q3B204|KGUA_CHLL3 Guanylate kinase OS=Chlorobium luteolum (str... 89.7 3e-19
sp|Q2YD10|KGUA_NITMU Guanylate kinase OS=Nitrosospira multiformis... 90.1 3e-19
sp|Q7U570|KGUA_PARMW Guanylate kinase OS=Parasynechococcus mareni... 89.4 3e-19
sp|Q88BE2|KGUA_PSESM Guanylate kinase OS=Pseudomonas syringae pv.... 90.1 3e-19
sp|Q4ZZY8|KGUA_PSEU2 Guanylate kinase OS=Pseudomonas syringae pv.... 90.1 3e-19
sp|Q5HPY1|KGUA_STAEQ Guanylate kinase OS=Staphylococcus epidermid... 89.7 4e-19
sp|Q9HTM2|KGUA_PSEAE Guanylate kinase OS=Pseudomonas aeruginosa (... 89.4 5e-19
sp|Q1QSI1|KGUA_CHRSD Guanylate kinase OS=Chromohalobacter salexig... 89.7 5e-19
sp|P72648|KGUA_SYNY3 Guanylate kinase OS=Synechocystis sp. (strai... 89.0 5e-19
sp|Q0A5V3|KGUA_ALKEH Guanylate kinase OS=Alkalilimnicola ehrlichi... 89.0 6e-19
sp|Q5M3I4|KGUA_STRT2 Guanylate kinase OS=Streptococcus thermophil... 89.0 7e-19
sp|Q5LYX1|KGUA_STRT1 Guanylate kinase OS=Streptococcus thermophil... 89.0 7e-19
sp|Q9JT96|KGUA_NEIMA Guanylate kinase OS=Neisseria meningitidis s... 89.0 8e-19
sp|Q9KX62|KGUA_MYCGA Guanylate kinase OS=Mycoplasmoides gallisept... 88.6 8e-19
sp|Q0I868|KGUA_SYNS3 Guanylate kinase OS=Synechococcus sp. (strai... 88.2 9e-19
sp|Q73HV1|KGUA_WOLPM Guanylate kinase OS=Wolbachia pipientis wMel... 88.6 9e-19
sp|P0C0M9|KGUA_STAES Guanylate kinase OS=Staphylococcus epidermid... 88.6 1e-18
sp|Q1G9H8|KGUA_LACDA Guanylate kinase OS=Lactobacillus delbruecki... 88.2 1e-18
sp|Q48Q15|KGUA_PSE14 Guanylate kinase OS=Pseudomonas savastanoi p... 88.6 1e-18
sp|Q1MRL0|KGUA_LAWIP Guanylate kinase OS=Lawsonia intracellularis... 88.2 2e-18
sp|Q96M69|LRGUK_HUMAN Leucine-rich repeat and guanylate kinase do... 93.6 2e-18
sp|Q5N570|KGUA_SYNP6 Guanylate kinase OS=Synechococcus sp. (strai... 86.7 3e-18
sp|Q9JYB5|KGUA_NEIMB Guanylate kinase OS=Neisseria meningitidis s... 87.4 3e-18
sp|Q65JT0|KGUA_BACLD Guanylate kinase OS=Bacillus licheniformis (... 87.0 3e-18
sp|Q7V2K9|KGUA_PROMP Guanylate kinase OS=Prochlorococcus marinus ... 86.7 3e-18
sp|Q5YTM7|KGUA_NOCFA Guanylate kinase OS=Nocardia farcinica (stra... 86.7 4e-18
sp|Q9RS38|KGUA_DEIRA Guanylate kinase OS=Deinococcus radiodurans ... 87.8 4e-18
sp|Q67PR9|KGUA_SYMTH Guanylate kinase OS=Symbiobacterium thermoph... 86.7 5e-18
sp|Q15Z10|KGUA_PSEA6 Guanylate kinase OS=Pseudoalteromonas atlant... 86.3 6e-18
sp|Q88WL7|KGUA_LACPL Guanylate kinase OS=Lactiplantibacillus plan... 86.3 7e-18
sp|Q8DNR5|KGUA_STRR6 Guanylate kinase OS=Streptococcus pneumoniae... 85.9 9e-18
sp|Q5GS56|KGUA_WOLTR Guanylate kinase OS=Wolbachia sp. subsp. Bru... 85.1 1e-17
sp|Q92AI1|KGUA_LISIN Guanylate kinase OS=Listeria innocua serovar... 85.5 1e-17
sp|Q97PA3|KGUA_STRPN Guanylate kinase OS=Streptococcus pneumoniae... 85.5 1e-17
sp|P0DB95|KGUA_STRPQ Guanylate kinase OS=Streptococcus pyogenes s... 85.1 2e-17
sp|Q48S18|KGUA_STRPM Guanylate kinase OS=Streptococcus pyogenes s... 85.1 2e-17
sp|Q1J5I6|KGUA_STRPF Guanylate kinase OS=Streptococcus pyogenes s... 85.1 2e-17
sp|Q1JFN7|KGUA_STRPD Guanylate kinase OS=Streptococcus pyogenes s... 85.1 2e-17
sp|Q1JKP6|KGUA_STRPC Guanylate kinase OS=Streptococcus pyogenes s... 85.1 2e-17
sp|Q1JAJ4|KGUA_STRPB Guanylate kinase OS=Streptococcus pyogenes s... 85.1 2e-17
sp|P65223|KGUA_STRP8 Guanylate kinase OS=Streptococcus pyogenes s... 85.1 2e-17
sp|Q5XAP1|KGUA_STRP6 Guanylate kinase OS=Streptococcus pyogenes s... 85.1 2e-17
sp|P0DB94|KGUA_STRP3 Guanylate kinase OS=Streptococcus pyogenes s... 85.1 2e-17
sp|Q3ALX6|KGUA_SYNSC Guanylate kinase OS=Synechococcus sp. (strai... 84.3 2e-17
sp|Q99YM5|KGUA_STRP1 Guanylate kinase OS=Streptococcus pyogenes s... 85.1 2e-17
sp|Q7WZE5|KGUA_SHEVD Guanylate kinase OS=Shewanella violacea (str... 85.1 2e-17
sp|Q31C67|KGUA_PROM9 Guanylate kinase OS=Prochlorococcus marinus ... 83.6 3e-17
sp|Q2S8R2|KGUA_HAHCH Guanylate kinase OS=Hahella chejuensis (stra... 84.3 3e-17
sp|Q4K3R4|KGUA_PSEF5 Guanylate kinase OS=Pseudomonas fluorescens ... 84.0 3e-17
sp|Q8KFS5|KGUA_CHLTE Guanylate kinase OS=Chlorobaculum tepidum (s... 83.6 4e-17
sp|Q0I5L8|KGUA_HISS1 Guanylate kinase OS=Histophilus somni (strai... 83.6 5e-17
sp|Q8KPQ7|KGUA_SYNE7 Guanylate kinase OS=Synechococcus elongatus ... 82.8 6e-17
sp|Q2GLF7|KGUA_ANAPZ Guanylate kinase OS=Anaplasma phagocytophilu... 83.6 6e-17
sp|Q8EJU6|KGUA_SHEON Guanylate kinase OS=Shewanella oneidensis (s... 83.2 7e-17
sp|Q21TP7|KGUA_ALBFT Guanylate kinase OS=Albidiferax ferrireducen... 83.2 7e-17
sp|Q5P3M0|KGUA_AROAE Guanylate kinase OS=Aromatoleum aromaticum (... 83.2 7e-17
sp|Q9D5S7|LRGUK_MOUSE Leucine-rich repeat and guanylate kinase do... 88.6 7e-17
sp|Q5X3P2|KGUA_LEGPA Guanylate kinase OS=Legionella pneumophila (... 82.8 9e-17
sp|Q3IJH8|KGUA_PSET1 Guanylate kinase OS=Pseudoalteromonas transl... 82.8 9e-17
sp|Q0VT94|KGUA_ALCBS Guanylate kinase OS=Alcanivorax borkumensis ... 82.8 1e-16
sp|Q30PL1|KGUA_SULDN Guanylate kinase OS=Sulfurimonas denitrifica... 82.8 1e-16
sp|Q5QYH9|KGUA_IDILO Guanylate kinase OS=Idiomarina loihiensis (s... 82.8 1e-16
sp|Q12IL8|KGUA_SHEDO Guanylate kinase OS=Shewanella denitrificans... 82.4 1e-16
sp|Q7VIA1|KGUA_HELHP Guanylate kinase OS=Helicobacter hepaticus (... 82.4 1e-16
sp|Q7VRJ7|KGUA_BLOFL Guanylate kinase OS=Blochmannia floridanus O... 82.4 1e-16
sp|Q47UB3|KGUA_COLP3 Guanylate kinase OS=Colwellia psychrerythrae... 82.4 2e-16
sp|Q8Z2H9|KGUA_SALTI Guanylate kinase OS=Salmonella typhi OX=9037... 82.0 2e-16
sp|Q5PC40|KGUA_SALPA Guanylate kinase OS=Salmonella paratyphi A (... 82.0 2e-16
sp|Q83EL7|KGUA_COXBU Guanylate kinase OS=Coxiella burnetii (strai... 82.0 2e-16
sp|Q5WFK3|KGUA_SHOC1 Guanylate kinase OS=Shouchella clausii (stra... 82.0 2e-16
sp|Q3AQL3|KGUA_CHLCH Guanylate kinase OS=Chlorobium chlorochromat... 81.6 2e-16
sp|Q9X6M5|KGUA_SALTY Guanylate kinase OS=Salmonella typhimurium (... 82.0 2e-16
sp|Q5ZTZ8|KGUA_LEGPH Guanylate kinase OS=Legionella pneumophila s... 82.0 2e-16
sp|Q5WV30|KGUA_LEGPL Guanylate kinase OS=Legionella pneumophila (... 81.6 2e-16
sp|Q088T7|KGUA_SHEFN Guanylate kinase OS=Shewanella frigidimarina... 81.6 2e-16
sp|Q6MDG3|KGUA_PARUW Guanylate kinase OS=Protochlamydia amoebophi... 81.3 2e-16
sp|Q21EC9|KGUA_SACD2 Guanylate kinase OS=Saccharophagus degradans... 81.6 2e-16
sp|Q7VDB6|KGUA_PROMA Guanylate kinase OS=Prochlorococcus marinus ... 80.9 3e-16
sp|Q9A7N9|KGUA_CAUVC Guanylate kinase OS=Caulobacter vibrioides (... 81.6 3e-16
sp|Q8DVK6|KGUA_STRMU Guanylate kinase OS=Streptococcus mutans ser... 81.3 3e-16
sp|Q87TA9|KGUA_VIBPA Guanylate kinase OS=Vibrio parahaemolyticus ... 81.3 3e-16
sp|Q3K4L8|KGUA_PSEPF Guanylate kinase OS=Pseudomonas fluorescens ... 81.3 3e-16
sp|Q4FQY7|KGUA_PSYA2 Guanylate kinase OS=Psychrobacter arcticus (... 81.3 4e-16
sp|Q0HZX1|KGUA_SHESR Guanylate kinase OS=Shewanella sp. (strain M... 80.9 4e-16
sp|Q57I92|KGUA_SALCH Guanylate kinase OS=Salmonella choleraesuis ... 80.9 4e-16
sp|Q1Q973|KGUA_PSYCK Guanylate kinase OS=Psychrobacter cryohalole... 80.9 4e-16
sp|Q4FMR1|KGUA_PELUB Guanylate kinase OS=Pelagibacter ubique (str... 80.9 4e-16
sp|Q8ER28|KGUA_OCEIH Guanylate kinase OS=Oceanobacillus iheyensis... 80.9 5e-16
sp|Q2JQ59|KGUA_SYNJB Guanylate kinase OS=Synechococcus sp. (strai... 81.3 5e-16
sp|Q31UQ6|KGUA_SHIBS Guanylate kinase OS=Shigella boydii serotype... 80.9 5e-16
sp|Q3AC14|KGUA_CARHZ Guanylate kinase OS=Carboxydothermus hydroge... 80.9 5e-16
sp|Q329K8|KGUA_SHIDS Guanylate kinase OS=Shigella dysenteriae ser... 80.9 5e-16
sp|Q5L0S8|KGUA_GEOKA Guanylate kinase OS=Geobacillus kaustophilus... 80.5 5e-16
sp|Q7NRL1|KGUA_CHRVO Guanylate kinase OS=Chromobacterium violaceu... 80.9 5e-16
sp|Q3YW11|KGUA_SHISS Guanylate kinase OS=Shigella sonnei (strain ... 80.5 5e-16
sp|P60548|KGUA_SHIFL Guanylate kinase OS=Shigella flexneri OX=623... 80.5 5e-16
sp|Q1R4U3|KGUA_ECOUT Guanylate kinase OS=Escherichia coli (strain... 80.5 5e-16
sp|P60546|KGUA_ECOLI Guanylate kinase OS=Escherichia coli (strain... 80.5 5e-16
sp|P60547|KGUA_ECOL6 Guanylate kinase OS=Escherichia coli O6:H1 (... 80.5 5e-16
sp|Q0TBG1|KGUA_ECOL5 Guanylate kinase OS=Escherichia coli O6:K15:... 80.5 5e-16
sp|Q9PQS9|KGUA_UREPA Guanylate kinase OS=Ureaplasma parvum serova... 80.1 6e-16
sp|P75526|KGUA_MYCPN Guanylate kinase OS=Mycoplasma pneumoniae (s... 81.3 6e-16
sp|Q827Q3|KGUA_STRAW Guanylate kinase OS=Streptomyces avermitilis... 80.1 6e-16
sp|Q0HE40|KGUA_SHESM Guanylate kinase OS=Shewanella sp. (strain M... 80.5 6e-16
sp|Q2NIH1|KGUA_AYWBP Guanylate kinase OS=Aster yellows witches'-b... 80.5 7e-16
sp|Q2JQB9|KGUA_SYNJA Guanylate kinase OS=Synechococcus sp. (strai... 80.5 7e-16
sp|P60554|KGUA_ONYPE Guanylate kinase OS=Onion yellows phytoplasm... 80.5 7e-16
sp|Q3A523|KGUA_SYNC1 Guanylate kinase OS=Syntrophotalea carbinoli... 80.1 8e-16
sp|Q9Z961|KGUA_CHLPN Guanylate kinase OS=Chlamydia pneumoniae OX=... 79.7 1e-15
sp|Q9KXS0|KGUA_STRCO Guanylate kinase OS=Streptomyces coelicolor ... 79.3 1e-15
sp|Q3J2A5|KGUA_CERS4 Guanylate kinase OS=Cereibacter sphaeroides ... 79.7 1e-15
sp|Q8XD88|KGUA_ECO57 Guanylate kinase OS=Escherichia coli O157:H7... 79.7 1e-15
sp|P60555|KGUA_PROMM Guanylate kinase OS=Prochlorococcus marinus ... 79.0 1e-15
sp|P60552|KGUA_LACJO Guanylate kinase OS=Lactobacillus johnsonii ... 79.3 1e-15
sp|Q12DV7|KGUA_POLSJ Guanylate kinase OS=Polaromonas sp. (strain ... 79.0 2e-15
sp|Q8GAU4|KGUA_STRKA Guanylate kinase OS=Streptomyces kasugaensis... 79.0 2e-15
sp|Q0S0L7|KGUA_RHOJR Guanylate kinase OS=Rhodococcus jostii (stra... 79.0 2e-15
sp|Q1IW06|KGUA_DEIGD Guanylate kinase OS=Deinococcus geothermalis... 79.7 2e-15
sp|Q6F7H0|KGUA_ACIAD Guanylate kinase OS=Acinetobacter baylyi (st... 79.0 2e-15
sp|Q895Q5|KGUA_CLOTE Guanylate kinase OS=Clostridium tetani (stra... 79.0 2e-15
sp|Q89AC8|KGUA_BUCBP Guanylate kinase OS=Buchnera aphidicola subs... 78.6 3e-15
sp|Q5HTT7|KGUA_CAMJR Guanylate kinase OS=Campylobacter jejuni (st... 78.6 3e-15
sp|Q9K9Y2|KGUA_HALH5 Guanylate kinase OS=Halalkalibacterium halod... 78.2 3e-15
sp|Q1CUI1|KGUA_HELPH Guanylate kinase OS=Helicobacter pylori (str... 78.2 3e-15
sp|Q9PNB8|KGUA_CAMJE Guanylate kinase OS=Campylobacter jejuni sub... 78.6 3e-15
sp|Q7MPW9|KGUA_VIBVY Guanylate kinase OS=Vibrio vulnificus (strai... 78.2 3e-15
sp|Q8DDV6|KGUA_VIBVU Guanylate kinase OS=Vibrio vulnificus (strai... 78.2 3e-15
sp|P56103|KGUA_HELPY Guanylate kinase OS=Helicobacter pylori (str... 78.2 3e-15
sp|Q9KNM4|KGUA_VIBCH Guanylate kinase OS=Vibrio cholerae serotype... 78.2 4e-15
sp|Q98PN5|KGUA_MYCPU Guanylate kinase OS=Mycoplasmopsis pulmonis ... 77.8 4e-15
sp|Q8Y672|KGUA_LISMO Guanylate kinase OS=Listeria monocytogenes s... 77.8 4e-15
sp|Q71YI9|KGUA_LISMF Guanylate kinase OS=Listeria monocytogenes s... 77.8 4e-15
sp|Q602T6|KGUA_METCA Guanylate kinase OS=Methylococcus capsulatus... 77.8 4e-15
sp|Q9ZMB7|KGUA_HELPJ Guanylate kinase OS=Helicobacter pylori (str... 77.8 5e-15
sp|Q92QZ2|KGUA_RHIME Guanylate kinase OS=Rhizobium meliloti (stra... 78.2 5e-15
sp|Q6G053|KGUA_BARQU Guanylate kinase OS=Bartonella quintana (str... 77.8 7e-15
sp|Q5FJH2|KGUA_LACAC Guanylate kinase OS=Lactobacillus acidophilu... 77.4 7e-15
sp|Q3JBT3|KGUA_NITOC Guanylate kinase OS=Nitrosococcus oceani (st... 77.4 7e-15
sp|P57509|KGUA_BUCAI Guanylate kinase OS=Buchnera aphidicola subs... 77.4 7e-15
sp|Q2J840|KGUA_FRACC Guanylate kinase OS=Frankia casuarinae (stra... 76.6 7e-15
sp|Q47R17|KGUA_THEFY Guanylate kinase OS=Thermobifida fusca (stra... 77.0 8e-15
sp|Q11HG8|KGUA_CHESB Guanylate kinase OS=Chelativorans sp. (strai... 77.0 1e-14
sp|Q28PK5|KGUA_JANSC Guanylate kinase OS=Jannaschia sp. (strain C... 77.0 1e-14
sp|Q182S8|KGUA_CLOD6 Guanylate kinase OS=Clostridioides difficile... 76.6 1e-14
sp|Q0BL54|KGUA_FRATO Guanylate kinase OS=Francisella tularensis s... 75.9 2e-14
sp|Q255A8|KGUA_CHLFF Guanylate kinase OS=Chlamydia felis (strain ... 76.3 2e-14
sp|Q2LQ62|KGUA_SYNAS Guanylate kinase OS=Syntrophus aciditrophicu... 76.3 2e-14
sp|Q1B9F6|KGUA_MYCSS Guanylate kinase OS=Mycobacterium sp. (strai... 75.9 2e-14
sp|O84033|KGUA_CHLTR Guanylate kinase OS=Chlamydia trachomatis (s... 76.3 2e-14
sp|Q3KMZ2|KGUA_CHLTA Guanylate kinase OS=Chlamydia trachomatis se... 76.3 2e-14
sp|Q6HEU4|KGUA_BACHK Guanylate kinase OS=Bacillus thuringiensis s... 75.9 2e-14
sp|Q636F5|KGUA_BACCZ Guanylate kinase OS=Bacillus cereus (strain ... 75.9 2e-14
sp|Q732K0|KGUA_BACC1 Guanylate kinase OS=Bacillus cereus (strain ... 75.9 2e-14
sp|Q81WG7|KGUA_BACAN Guanylate kinase OS=Bacillus anthracis OX=13... 75.9 2e-14
sp|Q2A2K6|KGUA_FRATH Guanylate kinase OS=Francisella tularensis s... 75.5 2e-14
sp|P44310|KGUA_HAEIN Guanylate kinase OS=Haemophilus influenzae (... 75.9 2e-14
sp|Q97ID0|KGUA_CLOAB Guanylate kinase OS=Clostridium acetobutylic... 75.9 2e-14
sp|Q8R9S6|KGUA_CALS4 Guanylate kinase OS=Caldanaerobacter subterr... 75.5 3e-14
sp|Q9CCQ7|KGUA_MYCLE Guanylate kinase OS=Mycobacterium leprae (st... 75.5 3e-14
sp|Q5E8P5|KGUA_ALIF1 Guanylate kinase OS=Aliivibrio fischeri (str... 75.5 3e-14
sp|Q9X215|KGUA_THEMA Guanylate kinase OS=Thermotoga maritima (str... 75.5 3e-14
sp|Q65RR5|KGUA_MANSM Guanylate kinase OS=Mannheimia succiniciprod... 75.1 4e-14
sp|Q4UK55|KGUA_RICFE Guanylate kinase OS=Rickettsia felis (strain... 74.7 4e-14
sp|Q4QJK3|KGUA_HAEI8 Guanylate kinase OS=Haemophilus influenzae (... 75.1 4e-14
sp|Q2NQS9|KGUA_SODGM Guanylate kinase OS=Sodalis glossinidius (st... 75.1 4e-14
sp|Q822M8|KGUA_CHLCV Guanylate kinase OS=Chlamydia caviae (strain... 75.1 5e-14
sp|Q7N9P2|KGUA_PHOLL Guanylate kinase OS=Photorhabdus laumondii s... 75.1 5e-14
sp|Q6AJ91|KGUA_DESPS Guanylate kinase OS=Desulfotalea psychrophil... 74.7 5e-14
sp|Q0AXK8|KGUA_SYNWW Guanylate kinase OS=Syntrophomonas wolfei su... 74.3 6e-14
sp|Q2W9C3|KGUA_MAGSA Guanylate kinase OS=Magnetospirillum magneti... 75.1 6e-14
sp|Q5NEY6|KGUA_FRATT Guanylate kinase OS=Francisella tularensis s... 74.3 6e-14
sp|Q14GD9|KGUA_FRAT1 Guanylate kinase OS=Francisella tularensis s... 74.3 6e-14
sp|Q39T72|KGUA_GEOMG Guanylate kinase OS=Geobacter metallireducen... 74.3 7e-14
sp|Q110R6|KGUA_TRIEI Guanylate kinase OS=Trichodesmium erythraeum... 73.9 7e-14
sp|Q24TX4|KGUA_DESHY Guanylate kinase OS=Desulfitobacterium hafni... 74.3 7e-14
sp|Q0AQC4|KGUA_MARMM Guanylate kinase OS=Maricaulis maris (strain... 74.7 8e-14
sp|Q46GV6|KGUA_PROMT Guanylate kinase OS=Prochlorococcus marinus ... 73.6 8e-14
sp|Q7MAK5|KGUA_WOLSU Guanylate kinase OS=Wolinella succinogenes (... 74.3 8e-14
sp|P57888|KGUA_PASMU Guanylate kinase OS=Pasteurella multocida (s... 74.3 9e-14
sp|Q2IX83|KGUA_RHOP2 Guanylate kinase OS=Rhodopseudomonas palustr... 74.3 9e-14
sp|Q7MWS7|KGUA_PORGI Guanylate kinase OS=Porphyromonas gingivalis... 73.6 1e-13
sp|Q6G439|KGUA_BARHE Guanylate kinase OS=Bartonella henselae (str... 74.3 1e-13
sp|P60551|KGUA_GEOSL Guanylate kinase OS=Geobacter sulfurreducens... 73.9 1e-13
sp|Q1IK22|KGUA_KORVE Guanylate kinase OS=Koribacter versatilis (s... 74.7 1e-13
sp|Q7NK59|KGUA_GLOVI Guanylate kinase OS=Gloeobacter violaceus (s... 73.9 1e-13
sp|P60553|KGUA_MYCPA Guanylate kinase OS=Mycolicibacterium paratu... 74.3 1e-13
sp|Q1LQ34|KGUA_CUPMC Guanylate kinase OS=Cupriavidus metalliduran... 73.9 1e-13
sp|Q6AF82|KGUA_LEIXX Guanylate kinase OS=Leifsonia xyli subsp. xy... 74.7 1e-13
sp|Q31DP7|KGUA_HYDCU Guanylate kinase OS=Hydrogenovibrio crunogen... 73.6 1e-13
sp|Q479A8|KGUA_DECAR Guanylate kinase OS=Dechloromonas aromatica ... 73.2 2e-13
sp|Q66GE5|KGUA_YERPS Guanylate kinase OS=Yersinia pseudotuberculo... 73.6 2e-13
sp|Q1CCZ3|KGUA_YERPN Guanylate kinase OS=Yersinia pestis bv. Anti... 73.6 2e-13
sp|Q8ZJQ2|KGUA_YERPE Guanylate kinase OS=Yersinia pestis OX=632 G... 73.6 2e-13
sp|Q1C258|KGUA_YERPA Guanylate kinase OS=Yersinia pestis bv. Anti... 73.6 2e-13
sp|Q819T6|KGUA_BACCR Guanylate kinase OS=Bacillus cereus (strain ... 73.2 2e-13
sp|Q2L090|KGUA_BORA1 Guanylate kinase OS=Bordetella avium (strain... 73.2 2e-13
sp|Q9PL09|KGUA_CHLMU Guanylate kinase OS=Chlamydia muridarum (str... 73.2 2e-13
sp|P9WKE9|KGUA_MYCTU Guanylate kinase OS=Mycobacterium tuberculos... 73.2 2e-13
sp|P9WKE8|KGUA_MYCTO Guanylate kinase OS=Mycobacterium tuberculos... 73.2 2e-13
sp|P0A5I5|KGUA_MYCBO Guanylate kinase OS=Mycobacterium bovis (str... 73.2 2e-13
sp|Q8G813|KGUA_BIFLO Guanylate kinase OS=Bifidobacterium longum (... 72.4 3e-13
sp|Q6DB60|KGUA_PECAS Guanylate kinase OS=Pectobacterium atrosepti... 72.4 4e-13
sp|Q82SQ3|KGUA_NITEU Guanylate kinase OS=Nitrosomonas europaea (s... 72.0 4e-13
sp|Q4A6S7|KGUA_MYCS5 Guanylate kinase OS=Mycoplasmopsis synoviae ... 72.0 4e-13
sp|Q8K9C7|KGUA_BUCAP Guanylate kinase OS=Buchnera aphidicola subs... 72.0 4e-13
sp|Q2S6J5|KGUA_SALRD Guanylate kinase OS=Salinibacter ruber (stra... 71.6 4e-13
sp|Q8UGD7|KGUA_AGRFC Guanylate kinase OS=Agrobacterium fabrum (st... 72.4 4e-13
sp|Q13V49|KGUA_PARXL Guanylate kinase OS=Paraburkholderia xenovor... 72.4 5e-13
sp|P65218|KGUA_BRUSU Guanylate kinase OS=Brucella suis biovar 1 (... 71.2 1e-12
sp|P65217|KGUA_BRUME Guanylate kinase OS=Brucella melitensis biot... 71.2 1e-12
sp|Q57EQ3|KGUA_BRUAB Guanylate kinase OS=Brucella abortus biovar ... 71.2 1e-12
sp|Q2YMJ2|KGUA_BRUA2 Guanylate kinase OS=Brucella abortus (strain... 71.2 1e-12
sp|P0C0M8|KGUA_STAEP Guanylate kinase (Fragment) OS=Staphylococcu... 68.9 1e-12
sp|Q46YE8|KGUA_CUPPJ Guanylate kinase OS=Cupriavidus pinatubonens... 71.2 1e-12
sp|Q5L5M1|KGUA_CHLAB Guanylate kinase OS=Chlamydia abortus (strai... 70.9 1e-12
sp|P60550|KGUA_CORDI Guanylate kinase OS=Corynebacterium diphther... 70.5 1e-12
sp|Q135N9|KGUA_RHOPS Guanylate kinase OS=Rhodopseudomonas palustr... 70.9 2e-12
sp|Q6LVP5|KGUA_PHOPR Guanylate kinase OS=Photobacterium profundum... 70.1 2e-12
sp|Q4JVH4|KGUA_CORJK Guanylate kinase OS=Corynebacterium jeikeium... 69.7 2e-12
sp|Q2IL45|KGUA_ANADE Guanylate kinase OS=Anaeromyxobacter dehalog... 70.5 3e-12
sp|Q8TDM6|DLG5_HUMAN Disks large homolog 5 OS=Homo sapiens OX=960... 74.3 3e-12
sp|Q1BY73|KGUA_BURO1 Guanylate kinase OS=Burkholderia orbicola (s... 70.1 3e-12
sp|Q7UP92|KGUA_RHOBA Guanylate kinase OS=Rhodopirellula baltica (... 69.7 3e-12
sp|Q1RK99|KGUA_RICBR Guanylate kinase OS=Rickettsia bellii (strai... 68.9 4e-12
sp|Q6F1S1|KGUA_MESFL Guanylate kinase OS=Mesoplasma florum (strai... 71.2 4e-12
sp|P47353|KGUA_MYCGE Guanylate kinase OS=Mycoplasma genitalium (s... 69.7 5e-12
sp|Q8EVJ9|KGUA_MALP2 Guanylate kinase OS=Malacoplasma penetrans (... 68.9 5e-12
sp|Q8FT45|KGUA_COREF Guanylate kinase OS=Corynebacterium efficien... 68.6 5e-12
sp|Q1D3A6|KGUA_MYXXD Guanylate kinase OS=Myxococcus xanthus (stra... 68.6 7e-12
sp|O95049|ZO3_HUMAN Tight junction protein ZO-3 OS=Homo sapiens O... 72.0 1e-11
sp|Q5NQE8|KGUA_ZYMMO Guanylate kinase OS=Zymomonas mobilis subsp.... 68.6 1e-11
sp|Q2KA85|KGUA_RHIEC Guanylate kinase OS=Rhizobium etli (strain C... 68.2 1e-11
sp|Q1LTY3|KGUA_BAUCH Guanylate kinase OS=Baumannia cicadellinicol... 67.8 1e-11
sp|Q5H3S2|KGUA_XANOR Guanylate kinase OS=Xanthomonas oryzae pv. o... 67.8 1e-11
sp|Q2P6N0|KGUA_XANOM Guanylate kinase OS=Xanthomonas oryzae pv. o... 67.8 1e-11
sp|Q3ZWD8|KGUA_DEHMC Guanylate kinase OS=Dehalococcoides mccartyi... 67.8 2e-11
sp|Q8D2E8|KGUA_WIGBR Guanylate kinase OS=Wigglesworthia glossinid... 67.4 2e-11
sp|Q39IL2|KGUA_BURL3 Guanylate kinase OS=Burkholderia lata (strai... 68.2 2e-11
sp|Q7VKP3|KGUA_HAEDU Guanylate kinase OS=Haemophilus ducreyi (str... 67.4 2e-11
sp|P60556|KGUA_RHOPA Guanylate kinase OS=Rhodopseudomonas palustr... 67.4 2e-11
sp|Q9ZCH7|KGUA_RICPR Guanylate kinase OS=Rickettsia prowazekii (s... 66.6 3e-11
sp|Q8NQ42|KGUA_CORGL Guanylate kinase OS=Corynebacterium glutamic... 66.6 3e-11
sp|Q83GE3|KGUA_TROWT Guanylate kinase OS=Tropheryma whipplei (str... 65.9 4e-11
sp|Q83HT8|KGUA_TROW8 Guanylate kinase OS=Tropheryma whipplei (str... 65.9 4e-11
sp|Q2SY72|KGUA_BURTA Guanylate kinase OS=Burkholderia thailandens... 66.6 5e-11
sp|Q9QXY1|ZO3_MOUSE Tight junction protein ZO-3 OS=Mus musculus O... 69.7 5e-11
sp|Q92GC9|KGUA_RICCN Guanylate kinase OS=Rickettsia conorii (stra... 66.6 6e-11
sp|Q8P5T7|KGUA_XANCP Guanylate kinase OS=Xanthomonas campestris p... 65.9 7e-11
sp|Q4UY41|KGUA_XANC8 Guanylate kinase OS=Xanthomonas campestris p... 65.9 7e-11
sp|Q984S9|KGUA_RHILO Guanylate kinase OS=Mesorhizobium japonicum ... 65.9 8e-11
sp|Q8PH65|KGUA_XANAC Guanylate kinase OS=Xanthomonas axonopodis p... 65.1 1e-10
sp|Q1GXB9|KGUA_METFK Guanylate kinase OS=Methylobacillus flagella... 64.7 1e-10
sp|Q1QKV7|KGUA_NITHX Guanylate kinase OS=Nitrobacter hamburgensis... 64.7 2e-10
sp|A0A0G2K2P5|ZO1_RAT Tight junction protein ZO-1 OS=Rattus norve... 68.2 2e-10
sp|Q2SSR8|KGUA_MYCCT Guanylate kinase OS=Mycoplasma capricolum su... 65.9 2e-10
sp|Q491W5|KGUA_BLOPB Guanylate kinase OS=Blochmannia pennsylvanic... 64.3 2e-10
sp|Q0C093|KGUA_HYPNA Guanylate kinase OS=Hyphomonas neptunium (st... 64.3 2e-10
sp|Q7VXZ3|KGUA_BORPE Guanylate kinase OS=Bordetella pertussis (st... 63.9 3e-10
sp|Q7W6B2|KGUA_BORPA Guanylate kinase OS=Bordetella parapertussis... 63.9 3e-10
sp|Q7WI80|KGUA_BORBR Guanylate kinase OS=Bordetella bronchiseptic... 63.9 3e-10
sp|Q3BPS0|KGUA_XANC5 Guanylate kinase OS=Xanthomonas campestris p... 63.5 3e-10
sp|Q3SRZ7|KGUA_NITWN Guanylate kinase OS=Nitrobacter winogradskyi... 63.9 3e-10
sp|Q07157|ZO1_HUMAN Tight junction protein ZO-1 OS=Homo sapiens O... 67.4 3e-10
sp|Q68VY3|KGUA_RICTY Guanylate kinase OS=Rickettsia typhi (strain... 63.5 4e-10
sp|Q89MV4|KGUA_BRADU Guanylate kinase OS=Bradyrhizobium diazoeffi... 63.9 4e-10
sp|O97758|ZO1_CANLF Tight junction protein ZO-1 OS=Canis lupus fa... 67.4 4e-10
sp|E9Q9R9|DLG5_MOUSE Disks large homolog 5 OS=Mus musculus OX=100... 67.4 4e-10
sp|Q1MJ02|KGUA_RHIJ3 Guanylate kinase OS=Rhizobium johnstonii (st... 63.5 4e-10
sp|Q1GNB4|KGUA_SPHAL Guanylate kinase OS=Sphingopyxis alaskensis ... 63.5 5e-10
sp|P39447|ZO1_MOUSE Tight junction protein ZO-1 OS=Mus musculus O... 67.0 5e-10
sp|Q8A677|KGUA_BACTN Guanylate kinase OS=Bacteroides thetaiotaomi... 63.2 6e-10
sp|Q9PD76|KGUA_XYLFA Guanylate kinase OS=Xylella fastidiosa (stra... 62.8 6e-10
sp|O62683|ZO3_CANLF Tight junction protein ZO-3 OS=Canis lupus fa... 65.9 8e-10
sp|Q5HAK7|KGUA_EHRRW Guanylate kinase OS=Ehrlichia ruminantium (s... 62.4 9e-10
sp|Q5FFZ9|KGUA_EHRRG Guanylate kinase OS=Ehrlichia ruminantium (s... 62.4 9e-10
sp|Q2G9M5|KGUA_NOVAD Guanylate kinase OS=Novosphingobium aromatic... 62.4 1e-09
sp|Q2GD44|KGUA_NEOSM Guanylate kinase OS=Neorickettsia sennetsu (... 62.0 1e-09
sp|Q215S7|KGUA_RHOPB Guanylate kinase OS=Rhodopseudomonas palustr... 62.0 1e-09
sp|Q95168|ZO2_CANLF Tight junction protein ZO-2 OS=Canis lupus fa... 65.5 1e-09
sp|Q9NPB6|PAR6A_HUMAN Partitioning defective 6 homolog alpha OS=H... 63.5 2e-09
sp|Q9UDY2|ZO2_HUMAN Tight junction protein ZO-2 OS=Homo sapiens O... 64.7 2e-09
sp|Q6MU25|KGUA_MYCMS Guanylate kinase OS=Mycoplasma mycoides subs... 62.8 2e-09
sp|Q6B4M5|PAR6A_RAT Partitioning defective 6 homolog alpha OS=Rat... 63.2 3e-09
sp|Q8XXF9|KGUA_RALN1 Guanylate kinase OS=Ralstonia nicotianae (st... 61.2 3e-09
sp|Q8RHI9|KGUA_FUSNN Guanylate kinase OS=Fusobacterium nucleatum ... 60.5 3e-09
sp|Q9Z101|PAR6A_MOUSE Partitioning defective 6 homolog alpha OS=M... 62.8 3e-09
sp|Q9Z0U1|ZO2_MOUSE Tight junction protein ZO-2 OS=Mus musculus O... 63.9 3e-09
sp|Q3YRE2|KGUA_EHRCJ Guanylate kinase OS=Ehrlichia canis (strain ... 60.8 4e-09
sp|Q4A8L2|KGUA_MESH7 Guanylate kinase OS=Mesomycoplasma hyopneumo... 60.5 4e-09
sp|Q0BPZ9|KGUA_GRABC Guanylate kinase OS=Granulibacter bethesdens... 60.1 6e-09
sp|Q5FS85|KGUA_GLUOX Guanylate kinase OS=Gluconobacter oxydans (s... 59.7 7e-09
sp|Q87DG5|KGUA_XYLFT Guanylate kinase OS=Xylella fastidiosa (stra... 58.9 1e-08
sp|Q2GHE0|KGUA_EHRCR Guanylate kinase OS=Ehrlichia chaffeensis (s... 58.9 2e-08
sp|Q63RV7|KGUA_BURPS Guanylate kinase OS=Burkholderia pseudomalle... 59.3 2e-08
sp|Q3JPS9|KGUA_BURP1 Guanylate kinase OS=Burkholderia pseudomalle... 59.3 2e-08
sp|Q62I00|KGUA_BURMA Guanylate kinase OS=Burkholderia mallei (str... 59.3 2e-08
sp|Q4AAI1|KGUA_MESHJ Guanylate kinase OS=Mesomycoplasma hyopneumo... 58.5 2e-08
sp|Q601H3|KGUA_MESH2 Guanylate kinase OS=Mesomycoplasma hyopneumo... 58.5 2e-08
sp|Q6A8H6|KGUA_CUTAK Guanylate kinase OS=Cutibacterium acnes (str... 57.4 4e-08
sp|Q9NAN2|PAR6_CAEEL Partitioning defective protein 6 OS=Caenorha... 57.8 1e-07
sp|Q10M74|GMK2_ORYSJ Guanylate kinase 2, chloroplastic/mitochondr... 57.0 2e-07
sp|Q9JK83|PAR6B_MOUSE Partitioning defective 6 homolog beta OS=Mu... 57.4 2e-07
sp|Q9BYG5|PAR6B_HUMAN Partitioning defective 6 homolog beta OS=Ho... 57.4 2e-07
sp|Q11XI0|KGUA_CYTH3 Guanylate kinase OS=Cytophaga hutchinsonii (... 55.1 2e-07
sp|Q64PY1|KGUA_BACFR Guanylate kinase OS=Bacteroides fragilis (st... 55.1 3e-07
sp|Q5L9N9|KGUA_BACFN Guanylate kinase OS=Bacteroides fragilis (st... 55.1 3e-07
sp|Q9BYG4|PAR6G_HUMAN Partitioning defective 6 homolog gamma OS=H... 56.6 3e-07
sp|Q9JK84|PAR6G_MOUSE Partitioning defective 6 homolog gamma OS=M... 56.6 3e-07
sp|Q2RXB1|KGUA_RHORT Guanylate kinase OS=Rhodospirillum rubrum (s... 54.3 7e-07
sp|Q3ZAF9|KGUA_DEHM1 Guanylate kinase OS=Dehalococcoides mccartyi... 52.8 2e-06
sp|Q6KH87|KGUA_MESM1 Guanylate kinase OS=Mesomycoplasma mobile (s... 52.4 2e-06
sp|P97879|GRIP1_RAT Glutamate receptor-interacting protein 1 OS=R... 53.5 6e-06
sp|Q925T6|GRIP1_MOUSE Glutamate receptor-interacting protein 1 OS... 53.5 7e-06
sp|Q9Y3R0|GRIP1_HUMAN Glutamate receptor-interacting protein 1 OS... 53.1 8e-06
sp|A1A5G4|MAGI3_XENTR Membrane-associated guanylate kinase, WW an... 53.1 9e-06
sp|Q9C0E4|GRIP2_HUMAN Glutamate receptor-interacting protein 2 OS... 52.8 1e-05
sp|Q5TCQ9|MAGI3_HUMAN Membrane-associated guanylate kinase, WW an... 52.8 1e-05
sp|Q9EQJ9|MAGI3_MOUSE Membrane-associated guanylate kinase, WW an... 52.4 2e-05
sp|Q9JK71|MAGI3_RAT Membrane-associated guanylate kinase, WW and ... 52.0 2e-05
sp|Q5F488|MAGI3_CHICK Membrane-associated guanylate kinase, WW an... 50.8 4e-05
sp|Q9WTW1|GRIP2_RAT Glutamate receptor-interacting protein 2 OS=R... 50.8 4e-05
sp|A8E0R9|GRIP2_XENLA Glutamate receptor-interacting protein 2 OS... 50.4 5e-05
sp|Q60631|GRB2_MOUSE Growth factor receptor-bound protein 2 OS=Mu... 46.6 2e-04
sp|P62994|GRB2_RAT Growth factor receptor-bound protein 2 OS=Ratt... 46.6 3e-04
sp|Q5R4J7|GRB2_PONAB Growth factor receptor-bound protein 2 OS=Po... 46.6 3e-04
sp|P62993|GRB2_HUMAN Growth factor receptor-bound protein 2 OS=Ho... 46.6 3e-04
sp|Q2KIB6|LIN7B_BOVIN Protein lin-7 homolog B OS=Bos taurus OX=99... 46.2 3e-04
sp|Q9HAP6|LIN7B_HUMAN Protein lin-7 homolog B OS=Homo sapiens OX=... 46.2 3e-04
sp|Q4L1J4|MAGI1_RAT Membrane-associated guanylate kinase, WW and ... 47.8 3e-04
sp|Q96QZ7|MAGI1_HUMAN Membrane-associated guanylate kinase, WW an... 47.8 4e-04
sp|Q9Z252|LIN7B_RAT Protein lin-7 homolog B OS=Rattus norvegicus ... 45.8 4e-04
sp|Q9ES64|USH1C_MOUSE Harmonin OS=Mus musculus OX=10090 GN=Ush1c ... 47.4 4e-04
sp|O88951|LIN7B_MOUSE Protein lin-7 homolog B OS=Mus musculus OX=... 45.4 4e-04
sp|Q94JM2|GMK3_ARATH Guanylate kinase 3, chloroplastic OS=Arabido... 46.2 5e-04
sp|Q6RHR9|MAGI1_MOUSE Membrane-associated guanylate kinase, WW an... 47.4 6e-04
sp|Q5F425|LIN7C_CHICK Protein lin-7 homolog C OS=Gallus gallus OX... 44.7 8e-04
sp|Q3MHQ0|USH1C_BOVIN Harmonin OS=Bos taurus OX=9913 GN=USH1C PE=... 46.2 8e-04
sp|Q792I0|LIN7C_RAT Protein lin-7 homolog C OS=Rattus norvegicus ... 44.7 8e-04
sp|Q5RAA5|LIN7C_PONAB Protein lin-7 homolog C OS=Pongo abelii OX=... 44.7 8e-04
sp|O88952|LIN7C_MOUSE Protein lin-7 homolog C OS=Mus musculus OX=... 44.7 8e-04
sp|Q9NUP9|LIN7C_HUMAN Protein lin-7 homolog C OS=Homo sapiens OX=... 44.7 8e-04
sp|Q0P5F3|LIN7C_BOVIN Protein lin-7 homolog C OS=Bos taurus OX=99... 44.7 8e-04
sp|Q99NH2|PARD3_MOUSE Partitioning defective 3 homolog OS=Mus mus... 46.6 0.001
sp|Q9Z340|PARD3_RAT Partitioning defective 3 homolog OS=Rattus no... 46.2 0.001
sp|Q80U72|SCRIB_MOUSE Protein scribble homolog OS=Mus musculus OX... 46.2 0.001
sp|Q8TEW0|PARD3_HUMAN Partitioning defective 3 homolog OS=Homo sa... 45.8 0.001
sp|Q0U6X7|HSE1_PHANO Class E vacuolar protein-sorting machinery p... 45.4 0.002
sp|Q9Y6V0|PCLO_HUMAN Protein piccolo OS=Homo sapiens OX=9606 GN=P... 45.8 0.002
sp|Q14160|SCRIB_HUMAN Protein scribble homolog OS=Homo sapiens OX... 45.4 0.002
sp|Q29498|NOS1_SHEEP Nitric oxide synthase 1 OS=Ovis aries OX=994... 45.1 0.002
sp|P87379|GRB2A_XENLA Growth factor receptor-bound protein 2-A OS... 43.9 0.002
sp|Q66II3|GRB2_XENTR Growth factor receptor-bound protein 2 OS=Xe... 43.5 0.002
sp|P29475|NOS1_HUMAN Nitric oxide synthase 1 OS=Homo sapiens OX=9... 45.1 0.002
sp|O19132|NOS1_RABIT Nitric oxide synthase 1 OS=Oryctolagus cunic... 45.1 0.002
sp|Q9Z250|LIN7A_RAT Protein lin-7 homolog A OS=Rattus norvegicus ... 43.5 0.003
sp|Q8JZS0|LIN7A_MOUSE Protein lin-7 homolog A OS=Mus musculus OX=... 43.5 0.003
sp|O14910|LIN7A_HUMAN Protein lin-7 homolog A OS=Homo sapiens OX=... 43.5 0.003
sp|Q32LM6|LIN7A_BOVIN Protein lin-7 homolog A OS=Bos taurus OX=99... 43.5 0.003
sp|Q4H4B6|SCRIB_DANRE Protein scribble homolog OS=Danio rerio OX=... 44.7 0.003
sp|Q6DFG0|RH21A_XENLA Rho GTPase-activating protein 21-A OS=Xenop... 44.3 0.004
sp|A2RUV4|RHG21_XENTR Rho GTPase-activating protein 21 OS=Xenopus... 44.3 0.004
sp|Q9WVQ1|MAGI2_MOUSE Membrane-associated guanylate kinase, WW an... 44.3 0.005
sp|Q71M21|RH21B_XENLA Rho GTPase-activating protein 21-B OS=Xenop... 44.3 0.005
sp|Q6GPJ9|GRB2B_XENLA Growth factor receptor-bound protein 2-B OS... 42.4 0.006
sp|O88382|MAGI2_RAT Membrane-associated guanylate kinase, WW and ... 43.9 0.006
sp|Q9NZM3|ITSN2_HUMAN Intersectin-2 OS=Homo sapiens OX=9606 GN=IT... 43.9 0.006
sp|Q86UL8|MAGI2_HUMAN Membrane-associated guanylate kinase, WW an... 43.9 0.006
sp|Q9QYX7|PCLO_MOUSE Protein piccolo OS=Mus musculus OX=10090 GN=... 43.9 0.007
sp|Q07883|GRB2_CHICK Growth factor receptor-bound protein 2 OS=Ga... 42.0 0.007
sp|O15018|PDZD2_HUMAN PDZ domain-containing protein 2 OS=Homo sap... 43.1 0.011
sp|Q6DFV3|RHG21_MOUSE Rho GTPase-activating protein 21 OS=Mus mus... 43.1 0.011
sp|Q9WVE9|ITSN1_RAT Intersectin-1 OS=Rattus norvegicus OX=10116 G... 43.1 0.011
sp|Q925E1|SNTG1_MOUSE Gamma-1-syntrophin OS=Mus musculus OX=10090... 42.4 0.012
sp|O55164|MPDZ_RAT Multiple PDZ domain protein OS=Rattus norvegic... 42.7 0.012
sp|O35430|APBA1_RAT Amyloid-beta A4 precursor protein-binding fam... 42.7 0.012
sp|B2RUJ5|APBA1_MOUSE Amyloid-beta A4 precursor protein-binding f... 42.7 0.013
sp|Q5T5U3|RHG21_HUMAN Rho GTPase-activating protein 21 OS=Homo sa... 42.7 0.013
sp|Q02410|APBA1_HUMAN Amyloid-beta A4 precursor protein-binding f... 42.7 0.013
sp|Q9QZR8|PDZD2_RAT PDZ domain-containing protein 2 OS=Rattus nor... 42.7 0.014
sp|Q69ZH9|RHG23_MOUSE Rho GTPase-activating protein 23 OS=Mus mus... 42.7 0.014
sp|F1MAD2|INADL_RAT InaD-like protein OS=Rattus norvegicus OX=101... 42.7 0.014
sp|O75970|MPDZ_HUMAN Multiple PDZ domain protein OS=Homo sapiens ... 42.7 0.014
sp|Q9PU36|PCLO_CHICK Protein piccolo (Fragment) OS=Gallus gallus ... 42.7 0.015
sp|Q63ZW7|INADL_MOUSE InaD-like protein OS=Mus musculus OX=10090 ... 42.4 0.017
sp|Q3UHD6|SNX27_MOUSE Sorting nexin-27 OS=Mus musculus OX=10090 G... 42.0 0.018
sp|Q8NI35|INADL_HUMAN InaD-like protein OS=Homo sapiens OX=9606 G... 42.4 0.018
sp|Q8K4V4|SNX27_RAT Sorting nexin-27 OS=Rattus norvegicus OX=1011... 42.0 0.018
sp|A5PKA5|SNX27_BOVIN Sorting nexin-27 OS=Bos taurus OX=9913 GN=S... 42.0 0.019
sp|Q9Y6N9|USH1C_HUMAN Harmonin OS=Homo sapiens OX=9606 GN=USH1C P... 42.0 0.020
sp|Q9Z0R6|ITSN2_MOUSE Intersectin-2 OS=Mus musculus OX=10090 GN=I... 42.0 0.021
sp|P29476|NOS1_RAT Nitric oxide synthase 1 OS=Rattus norvegicus O... 42.0 0.025
sp|Q9Z0J4|NOS1_MOUSE Nitric oxide synthase 1 OS=Mus musculus OX=1... 41.6 0.027
sp|Q9NSN8|SNTG1_HUMAN Gamma-1-syntrophin OS=Homo sapiens OX=9606 ... 41.2 0.029
sp|Q9ULJ8|NEB1_HUMAN Neurabin-1 OS=Homo sapiens OX=9606 GN=PPP1R9... 41.6 0.030
sp|Q9NY99|SNTG2_HUMAN Gamma-2-syntrophin OS=Homo sapiens OX=9606 ... 41.2 0.030
sp|O35867|NEB1_RAT Neurabin-1 OS=Rattus norvegicus OX=10116 GN=Pp... 41.6 0.031
sp|P29355|SEM5_CAEEL Sex muscle abnormal protein 5 OS=Caenorhabdi... 40.0 0.034
sp|Q9Z0R4|ITSN1_MOUSE Intersectin-1 OS=Mus musculus OX=10090 GN=I... 41.2 0.034
sp|E2QYC9|INADL_CANLF InaD-like protein OS=Canis lupus familiaris... 41.2 0.035
sp|Q9HD26|GOPC_HUMAN Golgi-associated PDZ and coiled-coil motif-c... 40.4 0.050
sp|Q8BH60|GOPC_MOUSE Golgi-associated PDZ and coiled-coil motif-c... 40.4 0.053
sp|P98084|APBA2_MOUSE Amyloid-beta A4 precursor protein-binding f... 40.4 0.063
sp|Q99767|APBA2_HUMAN Amyloid-beta A4 precursor protein-binding f... 40.4 0.065
sp|Q12923|PTN13_HUMAN Tyrosine-protein phosphatase non-receptor t... 40.0 0.082
sp|Q8VBX6|MPDZ_MOUSE Multiple PDZ domain protein OS=Mus musculus ... 40.0 0.083
sp|Q9V9S7|SYDE_DROME Rho GTPase-activating protein 100F OS=Drosop... 40.0 0.090
sp|P0CY30|SEC4_CANAX Ras-related protein SEC4 OS=Candida albicans... 38.5 0.098
sp|C4YL11|SEC4_CANAW Ras-related protein SEC4 OS=Candida albicans... 38.5 0.098
sp|P0CY31|SEC4_CANAL Ras-related protein SEC4 OS=Candida albicans... 38.5 0.098
sp|Q4WHP5|HSE1_ASPFU Class E vacuolar protein-sorting machinery p... 39.7 0.10
sp|Q7ZYG4|OSTF1_XENLA Osteoclast-stimulating factor 1 OS=Xenopus ... 38.5 0.11
sp|E9Q9W7|PDZD7_MOUSE PDZ domain-containing protein 7 OS=Mus musc... 39.7 0.11
sp|Q9CX99|GRAP_MOUSE GRB2-related adapter protein OS=Mus musculus... 38.1 0.13
sp|A6QLK6|GRAP_BOVIN GRB2-related adapter protein OS=Bos taurus O... 38.1 0.13
sp|Q64512|PTN13_MOUSE Tyrosine-protein phosphatase non-receptor t... 39.3 0.14
sp|Q8MJ49|OSTF1_PIG Osteoclast-stimulating factor 1 OS=Sus scrofa... 38.1 0.15
sp|A1DFN5|HSE1_NEOFI Class E vacuolar protein-sorting machinery p... 38.9 0.16
sp|Q9XYM0|CRK_DROME Adapter molecule Crk OS=Drosophila melanogast... 38.5 0.16
sp|Q92882|OSTF1_HUMAN Osteoclast-stimulating factor 1 OS=Homo sap... 38.1 0.16
sp|O70248|APBA3_RAT Amyloid-beta A4 precursor protein-binding fam... 38.9 0.16
sp|Q9CSB4|PAR3L_MOUSE Partitioning defective 3 homolog B OS=Mus m... 39.3 0.17
sp|Q9P227|RHG23_HUMAN Rho GTPase-activating protein 23 OS=Homo sa... 39.3 0.17
sp|Q9JKS6|PCLO_RAT Protein piccolo OS=Rattus norvegicus OX=10116 ... 39.3 0.18
sp|Q9UQ26|RIMS2_HUMAN Regulating synaptic membrane exocytosis pro... 38.9 0.18
sp|Q9P202|WHRN_HUMAN Whirlin OS=Homo sapiens OX=9606 GN=WHRN PE=1... 38.9 0.18
sp|Q5RD33|APBA2_PONAB Amyloid-beta A4 precursor protein-binding f... 38.9 0.18
sp|P54283|CACB1_RAT Voltage-dependent L-type calcium channel subu... 38.9 0.18
sp|Q6IN97|FRP2L_HUMAN Putative protein FRMPD2-like OS=Homo sapien... 38.5 0.19
sp|Q9JIS1|RIMS2_RAT Regulating synaptic membrane exocytosis prote... 38.9 0.19
sp|Q6TGW5|OSTF1_DANRE Osteoclast-stimulating factor 1 OS=Danio re... 37.7 0.19
sp|Q96L92|SNX27_HUMAN Sorting nexin-27 OS=Homo sapiens OX=9606 GN... 38.5 0.21
sp|Q8MJ50|OSTF1_BOVIN Osteoclast-stimulating factor 1 OS=Bos taur... 37.4 0.23
sp|Q9EQZ7|RIMS2_MOUSE Regulating synaptic membrane exocytosis pro... 38.5 0.23
sp|Q6XJU9|OSTF1_MONAL Osteoclast-stimulating factor 1 OS=Monopter... 37.4 0.25
sp|Q14005|IL16_HUMAN Pro-interleukin-16 OS=Homo sapiens OX=9606 G... 38.5 0.25
sp|Q8R3Z5|CACB1_MOUSE Voltage-dependent L-type calcium channel su... 38.1 0.25
sp|A7E8B6|SLA1_SCLS1 Actin cytoskeleton-regulatory complex protei... 38.5 0.26
sp|Q5ZJJ9|OSTF1_CHICK Osteoclast-stimulating factor 1 OS=Gallus g... 37.0 0.27
sp|Q925E0|SNTG2_MOUSE Gamma-2-syntrophin OS=Mus musculus OX=10090... 38.1 0.29
sp|O34666|CTPA_BACSU Carboxy-terminal processing protease CtpA OS... 38.1 0.29
sp|Q15811|ITSN1_HUMAN Intersectin-1 OS=Homo sapiens OX=9606 GN=IT... 38.1 0.30
sp|Q9WVJ4|SYJ2B_RAT Synaptojanin-2-binding protein OS=Rattus norv... 36.2 0.31
sp|P34109|MYOD_DICDI Myosin ID heavy chain OS=Dictyostelium disco... 38.1 0.33
sp|O35431|APBA2_RAT Amyloid-beta A4 precursor protein-binding fam... 38.1 0.34
sp|Q5RBI7|PDZD7_PONAB PDZ domain-containing protein 7 OS=Pongo ab... 38.1 0.34
sp|P05433|GAGC_AVISC P47(GAG-CRK) protein OS=Avian sarcoma virus ... 37.7 0.34
sp|W6RTA4|CLA1_CAEEL Protein clarinet OS=Caenorhabditis elegans O... 38.1 0.37
sp|Q9H5P4|PDZD7_HUMAN PDZ domain-containing protein 7 OS=Homo sap... 38.1 0.37
sp|Q9D6K5|SYJ2B_MOUSE Synaptojanin-2-binding protein OS=Mus muscu... 35.8 0.37
sp|O62675|IL16_MACMU Pro-interleukin-16 OS=Macaca mulatta OX=9544... 37.7 0.37
sp|O62674|IL16_CHLAE Pro-interleukin-16 OS=Chlorocebus aethiops O... 37.7 0.41
sp|Q8TEW8|PAR3L_HUMAN Partitioning defective 3 homolog B OS=Homo ... 37.7 0.42
sp|Q68DX3|FRPD2_HUMAN FERM and PDZ domain-containing protein 2 OS... 37.7 0.42
sp|O54824|IL16_MOUSE Pro-interleukin-16 OS=Mus musculus OX=10090 ... 37.7 0.47
sp|Q0V8R5|IL16_BOVIN Pro-interleukin-16 OS=Bos taurus OX=9913 GN=... 37.4 0.48
sp|Q0CJU8|HSE1_ASPTN Class E vacuolar protein-sorting machinery p... 37.4 0.50
sp|Q04929|CRK_CHICK Adapter molecule crk OS=Gallus gallus OX=9031... 37.0 0.51
sp|O62666|IL16_PANTR Pro-interleukin-16 OS=Pan troglodytes OX=959... 37.4 0.52
sp|P0A1B9|SCTN1_SALTY SPI-1 type 3 secretion system ATPase OS=Sal... 37.0 0.54
sp|P0A1C0|SCTN1_SALTI SPI-1 type 3 secretion system ATPase OS=Sal... 37.0 0.54
sp|O62678|IL16_AOTTR Pro-interleukin-16 OS=Aotus trivirgatus OX=9... 37.4 0.56
sp|Q1E878|HSE1_COCIM Class E vacuolar protein-sorting machinery p... 37.4 0.57
sp|Q63768|CRK_RAT Adapter molecule crk OS=Rattus norvegicus OX=10... 36.6 0.57
sp|Q9QY53|NPHP1_MOUSE Nephrocystin-1 OS=Mus musculus OX=10090 GN=... 37.4 0.58
sp|Q86UR5|RIMS1_HUMAN Regulating synaptic membrane exocytosis pro... 37.4 0.60
sp|P46108|CRK_HUMAN Adapter molecule crk OS=Homo sapiens OX=9606 ... 36.6 0.61
sp|O62677|IL16_SAISC Pro-interleukin-16 OS=Saimiri sciureus OX=95... 37.0 0.61
sp|O62676|IL16_MACFA Pro-interleukin-16 OS=Macaca fascicularis OX... 37.0 0.62
sp|Q3T0C9|SYJ2B_BOVIN Synaptojanin-2-binding protein OS=Bos tauru... 35.4 0.62
sp|Q64010|CRK_MOUSE Adapter molecule crk OS=Mus musculus OX=10090... 36.6 0.62
sp|Q9MZL7|CACB1_BOVIN Voltage-dependent L-type calcium channel su... 37.0 0.65
sp|Q13588|GRAP_HUMAN GRB2-related adapter protein OS=Homo sapiens... 36.2 0.68
sp|Q9F0W4|NOSZ_PSEFL Nitrous-oxide reductase OS=Pseudomonas fluor... 37.0 0.68
sp|Q9JJ40|NHRF3_RAT Na(+)/H(+) exchange regulatory cofactor NHE-R... 37.0 0.69
sp|P19517|CACB1_RABIT Voltage-dependent L-type calcium channel su... 37.0 0.72
sp|A5IMD9|DER_THEP1 GTPase Der OS=Thermotoga petrophila (strain A... 36.6 0.73
sp|Q9JIR4|RIMS1_RAT Regulating synaptic membrane exocytosis prote... 37.0 0.74
sp|A2QW93|HSE1_ASPNC Class E vacuolar protein-sorting machinery p... 37.0 0.74
sp|Q2KJA1|SH3G1_BOVIN Endophilin-A2 OS=Bos taurus OX=9913 GN=SH3G... 36.6 0.78
sp|Q02641|CACB1_HUMAN Voltage-dependent L-type calcium channel su... 36.6 0.78
sp|Q6GGY8|CTPAL_STAAR Probable CtpA-like serine protease OS=Staph... 36.6 0.83
sp|P57105|SYJ2B_HUMAN Synaptojanin-2-binding protein OS=Homo sapi... 35.0 0.83
sp|Q7A5M9|CTPAL_STAAN Probable CtpA-like serine protease OS=Staph... 36.6 0.84
sp|Q99U67|CTPAL_STAAM Probable CtpA-like serine protease OS=Staph... 36.6 0.84
sp|Q99NE5|RIMS1_MOUSE Regulating synaptic membrane exocytosis pro... 37.0 0.85
sp|Q7KRY7|SCRIB_DROME Protein lap4 OS=Drosophila melanogaster OX=... 36.6 0.90
sp|Q80VW5|WHRN_MOUSE Whirlin OS=Mus musculus OX=10090 GN=Whrn PE=... 36.6 0.96
sp|A1CEK6|HSE1_ASPCL Class E vacuolar protein-sorting machinery p... 36.6 0.97
sp|Q3T0X8|NHRF3_BOVIN Na(+)/H(+) exchange regulatory cofactor NHE... 36.2 0.99
sp|A7UA95|RADIL_DANRE Ras-associating and dilute domain-containin... 36.6 1.1
sp|Q16A32|RBKTP_ROSDO Bifunctional ribose 1,5-bisphosphokinase-th... 36.2 1.1
sp|Q61235|SNTB2_MOUSE Beta-2-syntrophin OS=Mus musculus OX=10090 ... 36.2 1.1
sp|Q2GT05|HSE1_CHAGB Class E vacuolar protein-sorting machinery p... 36.2 1.1
sp|Q99961|SH3G1_HUMAN Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH... 35.8 1.1
sp|Q69Z89|RADIL_MOUSE Ras-associating and dilute domain-containin... 36.2 1.1
sp|O42287|ITSN1_XENLA Intersectin-1 OS=Xenopus laevis OX=8355 GN=... 36.2 1.2
sp|Q2YXZ9|CTPAL_STAAB Probable CtpA-like serine protease OS=Staph... 36.2 1.2
sp|O96018|APBA3_HUMAN Amyloid-beta A4 precursor protein-binding f... 36.2 1.2
sp|Q5HG01|CTPAL_STAAC Probable CtpA-like serine protease OS=Staph... 36.2 1.2
sp|Q8NWR2|CTPAL_STAAW Probable CtpA-like serine protease OS=Staph... 36.2 1.2
sp|Q6G9E1|CTPAL_STAAS Probable CtpA-like serine protease OS=Staph... 36.2 1.2
sp|Q6CVA8|HSE1_KLULA Class E vacuolar protein-sorting machinery p... 36.2 1.2
sp|Q13425|SNTB2_HUMAN Beta-2-syntrophin OS=Homo sapiens OX=9606 G... 36.2 1.2
sp|Q9X1F8|DER_THEMA GTPase Der OS=Thermotoga maritima (strain ATC... 35.8 1.3
sp|Q6CHN0|SLA1_YARLI Actin cytoskeleton-regulatory complex protei... 36.2 1.3
sp|Q62422|OSTF1_MOUSE Osteoclast-stimulating factor 1 OS=Mus musc... 35.0 1.3
sp|Q6P686|OSTF1_RAT Osteoclast-stimulating factor 1 OS=Rattus nor... 35.0 1.4
sp|P42690|SRK4_SPOLA Tyrosine-protein kinase isoform SRK4 OS=Spon... 35.8 1.4
sp|E7FDW2|PZR3B_DANRE E3 ubiquitin-protein ligase PDZRN3-B OS=Dan... 36.2 1.4
sp|Q75DS3|HSE1_EREGS Class E vacuolar protein-sorting machinery p... 35.8 1.4
sp|P55196|AFAD_HUMAN Afadin OS=Homo sapiens OX=9606 GN=AFDN PE=1 ... 36.2 1.5
sp|Q13884|SNTB1_HUMAN Beta-1-syntrophin OS=Homo sapiens OX=9606 G... 35.8 1.5
sp|P70297|STAM1_MOUSE Signal transducing adapter molecule 1 OS=Mu... 35.8 1.5
sp|O55043|ARHG7_RAT Rho guanine nucleotide exchange factor 7 OS=R... 35.8 1.6
sp|Q9QZQ1|AFAD_MOUSE Afadin OS=Mus musculus OX=10090 GN=Afdn PE=1... 35.8 1.6
sp|Q9JIL4|NHRF3_MOUSE Na(+)/H(+) exchange regulatory cofactor NHE... 35.8 1.6
sp|P42686|SRK1_SPOLA Tyrosine-protein kinase isoform SRK1 OS=Spon... 35.8 1.6
sp|O35889|AFAD_RAT Afadin OS=Rattus norvegicus OX=10116 GN=Afdn P... 35.8 1.6
sp|Q8AXV0|SH3G1_CHICK Endophilin-A2 OS=Gallus gallus OX=9031 GN=S... 35.4 1.7
sp|Q9ES28|ARHG7_MOUSE Rho guanine nucleotide exchange factor 7 OS... 35.8 1.7
sp|P87378|CRK_XENLA Adapter molecule crk OS=Xenopus laevis OX=835... 35.4 1.7
sp|Q62419|SH3G1_MOUSE Endophilin-A2 OS=Mus musculus OX=10090 GN=S... 35.4 1.7
sp|Q557J6|DBNL_DICDI Drebrin-like protein OS=Dictyostelium discoi... 35.4 1.8
sp|Q99L88|SNTB1_MOUSE Beta-1-syntrophin OS=Mus musculus OX=10090 ... 35.4 1.8
sp|Q92783|STAM1_HUMAN Signal transducing adapter molecule 1 OS=Ho... 35.4 1.9
sp|P16885|PLCG2_HUMAN 1-phosphatidylinositol 4,5-bisphosphate pho... 35.4 2.0
sp|O35964|SH3G1_RAT Endophilin-A2 OS=Rattus norvegicus OX=10116 G... 35.0 2.0
sp|Q810W9|WHRN_RAT Whirlin OS=Rattus norvegicus OX=10116 GN=Whrn ... 35.4 2.0
sp|B1LBI4|DER_THESQ GTPase Der OS=Thermotoga sp. (strain RQ2) OX=... 35.0 2.2
sp|Q6C2N2|HSE1_YARLI Class E vacuolar protein-sorting machinery p... 35.4 2.2
sp|Q61085|RHPN1_MOUSE Rhophilin-1 OS=Mus musculus OX=10090 GN=Rhp... 35.0 2.5
sp|Q6QA76|PDZ11_PIG PDZ domain-containing protein 11 OS=Sus scrof... 33.5 2.6
sp|Q32LE7|PDZ11_BOVIN PDZ domain-containing protein 11 OS=Bos tau... 33.5 2.6
sp|Q9CZG9|PDZ11_MOUSE PDZ domain-containing protein 11 OS=Mus mus... 33.5 2.7
sp|B9K8E0|DER_THENN GTPase Der OS=Thermotoga neapolitana (strain ... 35.0 2.7
sp|Q14155|ARHG7_HUMAN Rho guanine nucleotide exchange factor 7 OS... 35.0 2.7
sp|Q62420|SH3G2_MOUSE Endophilin-A1 OS=Mus musculus OX=10090 GN=S... 34.7 2.8
sp|F1LRS8|CD2AP_RAT CD2-associated protein OS=Rattus norvegicus O... 35.0 2.8
sp|Q0P5E6|SNTA1_BOVIN Alpha-1-syntrophin OS=Bos taurus OX=9913 GN... 35.0 2.8
sp|Q7S6J4|HSE1_NEUCR Class E vacuolar protein-sorting machinery p... 35.0 2.9
sp|Q6ZMN7|PZRN4_HUMAN PDZ domain-containing RING finger protein 4... 35.0 2.9
sp|Q13424|SNTA1_HUMAN Alpha-1-syntrophin OS=Homo sapiens OX=9606 ... 34.7 3.0
sp|Q8CIH5|PLCG2_MOUSE 1-phosphatidylinositol 4,5-bisphosphate pho... 35.0 3.1
sp|Q9JLQ0|CD2AP_MOUSE CD2-associated protein OS=Mus musculus OX=1... 34.7 3.1
sp|P24135|PLCG2_RAT 1-phosphatidylinositol 4,5-bisphosphate phosp... 35.0 3.1
sp|Q64434|PTK6_MOUSE Protein-tyrosine kinase 6 OS=Mus musculus OX... 34.7 3.2
sp|P38753|HSE1_YEAST Class E vacuolar protein-sorting machinery p... 34.7 3.3
sp|Q9UPQ7|PZRN3_HUMAN E3 ubiquitin-protein ligase PDZRN3 OS=Homo ... 34.7 3.3
sp|O00560|SDCB1_HUMAN Syntenin-1 OS=Homo sapiens OX=9606 GN=SDCBP... 34.3 3.3
sp|Q69ZS0|PZRN3_MOUSE E3 ubiquitin-protein ligase PDZRN3 OS=Mus m... 34.7 3.4
sp|Q99963|SH3G3_HUMAN Endophilin-A3 OS=Homo sapiens OX=9606 GN=SH... 34.3 3.5
sp|P68907|PZRN3_RAT E3 ubiquitin-protein ligase PDZRN3 OS=Rattus ... 34.7 3.7
sp|B7IE34|DER_THEAB GTPase Der OS=Thermosipho africanus (strain T... 34.3 3.8
sp|P62484|ABI2_MOUSE Abl interactor 2 OS=Mus musculus OX=10090 GN... 34.3 3.8
sp|A1ZAY1|DLISH_DROME SH3 domain-containing protein Dlish OS=Dros... 34.3 3.8
sp|O88888|APBA3_MOUSE Amyloid-beta A4 precursor protein-binding f... 34.3 3.9
sp|P27447|YES_XIPHE Tyrosine-protein kinase Yes OS=Xiphophorus he... 34.3 4.2
sp|O43586|PPIP1_HUMAN Proline-serine-threonine phosphatase-intera... 34.3 4.3
sp|Q10199|IMP2_SCHPO Septation protein imp2 OS=Schizosaccharomyce... 34.3 4.4
sp|Q865P3|NHRF3_RABIT Na(+)/H(+) exchange regulatory cofactor NHE... 34.3 4.7
sp|O35002|CTPB_BACSU Carboxy-terminal processing protease CtpB OS... 33.9 4.9
sp|F4KHG6|CTPA1_ARATH Carboxyl-terminal-processing peptidase 1, c... 33.9 5.0
sp|O35180|SH3G3_RAT Endophilin-A3 OS=Rattus norvegicus OX=10116 G... 33.9 5.2
sp|Q45670|THES_BACSJ Thermophilic serine proteinase OS=Bacillus s... 33.9 5.3
sp|Q6ZWJ1|STXB4_HUMAN Syntaxin-binding protein 4 OS=Homo sapiens ... 33.9 5.4
sp|A5IKF4|MNME_THEP1 tRNA modification GTPase MnmE OS=Thermotoga ... 33.9 5.5
sp|Q9NYB9|ABI2_HUMAN Abl interactor 2 OS=Homo sapiens OX=9606 GN=... 33.9 5.5
sp|B1L9N6|MNME_THESQ tRNA modification GTPase MnmE OS=Thermotoga ... 33.9 5.6
sp|Q80TH2|ERBIN_MOUSE Erbin OS=Mus musculus OX=10090 GN=Erbin PE=... 34.3 5.6
sp|Q9WYA4|MNME_THEMA tRNA modification GTPase MnmE OS=Thermotoga ... 33.9 5.9
sp|Q6BNP6|HSE1_DEBHA Class E vacuolar protein-sorting machinery p... 33.9 6.1
sp|Q24008|INAD_DROME Inactivation-no-after-potential D protein OS... 33.9 6.4
sp|Q93646|SNT1_CAEEL Syntrophin-1 OS=Caenorhabditis elegans OX=62... 33.5 6.5
sp|Q4KLN0|SDCB2_RAT Syntenin-2 OS=Rattus norvegicus OX=10116 GN=S... 33.5 6.7
sp|Q61234|SNTA1_MOUSE Alpha-1-syntrophin OS=Mus musculus OX=10090... 33.5 6.8
sp|Q28626|SNTA1_RABIT Alpha-1-syntrophin OS=Oryctolagus cuniculus... 33.5 6.9
sp|Q9NHC3|CED2_CAEEL Cell death abnormality protein 2 OS=Caenorha... 33.1 6.9
sp|Q9ES67|ARHGB_RAT Rho guanine nucleotide exchange factor 11 OS=... 33.9 7.1
sp|Q7SI59|CWC25_NEUCR Pre-mRNA-splicing factor cwc25 OS=Neurospor... 33.5 7.6
sp|O70263|LNX1_MOUSE E3 ubiquitin-protein ligase LNX OS=Mus muscu... 33.5 7.7
sp|Q5BBL4|HSE1_EMENI Class E vacuolar protein-sorting machinery p... 33.5 7.8
sp|Q86UT5|NHRF4_HUMAN Na(+)/H(+) exchange regulatory cofactor NHE... 33.5 7.9
sp|O17583|LIN10_CAEEL Protein lin-10 OS=Caenorhabditis elegans OX... 33.5 8.0
sp|Q14511|CASL_HUMAN Enhancer of filamentation 1 OS=Homo sapiens ... 33.5 9.1
sp|Q8IVF5|TIAM2_HUMAN Rho guanine nucleotide exchange factor TIAM... 33.5 9.1
sp|P53671|LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapiens OX=9606... 33.1 9.2
sp|D4ACE5|INTU_RAT Protein inturned OS=Rattus norvegicus OX=10116... 33.5 9.4
sp|Q9MZL3|CACB3_BOVIN Voltage-dependent L-type calcium channel su... 33.1 9.5
sp|P40996|SCD2_SCHPO Protein scd2/ral3 OS=Schizosaccharomyces pom... 33.1 9.5
sp|Q9QXN0|SHRM3_MOUSE Protein Shroom3 OS=Mus musculus OX=10090 GN... 33.5 9.9
>sp|Q8N3R9|PALS1_HUMAN Protein PALS1 OS=Homo sapiens OX=9606 GN=PALS1
PE=1 SV=3
Length=675
Score = 1398 bits (3619), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 675/675 (100%), Positives = 675/675 (100%), Gaps = 0/675 (0%)
Query 1 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR 60
MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR
Sbjct 1 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR 60
Query 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK 120
QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK
Sbjct 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK 120
Query 121 ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF 180
ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF
Sbjct 121 ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF 180
Query 181 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE 240
PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE
Sbjct 181 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE 240
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE
Sbjct 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD
Sbjct 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
Query 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK
Sbjct 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
Query 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR
Sbjct 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI
Sbjct 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP
Sbjct 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN
Sbjct 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
Query 661 KLDTEPQWVPSTWLR 675
KLDTEPQWVPSTWLR
Sbjct 661 KLDTEPQWVPSTWLR 675
>sp|Q5RDQ2|PALS1_PONAB Protein PALS1 OS=Pongo abelii OX=9601 GN=PALS1
PE=2 SV=1
Length=675
Score = 1393 bits (3606), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 672/675 (99%), Positives = 674/675 (99%), Gaps = 0/675 (0%)
Query 1 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR 60
MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR
Sbjct 1 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR 60
Query 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK 120
QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK
Sbjct 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK 120
Query 121 ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF 180
ILEIEDLFSSLKHIQHTL+DSQSQEDISLLLQLVQNK FQNAFKIHNAITVHMNKASPPF
Sbjct 121 ILEIEDLFSSLKHIQHTLIDSQSQEDISLLLQLVQNKGFQNAFKIHNAITVHMNKASPPF 180
Query 181 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE 240
PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE
Sbjct 181 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE 240
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE
Sbjct 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
VLEINGIEIRGKDVNEVFDLL+DMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD
Sbjct 301 VLEINGIEIRGKDVNEVFDLLADMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
Query 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK
Sbjct 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
Query 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR
Sbjct 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI
Sbjct 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP
Sbjct 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN
Sbjct 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
Query 661 KLDTEPQWVPSTWLR 675
KLDTEPQWVPSTWLR
Sbjct 661 KLDTEPQWVPSTWLR 675
>sp|E2QY99|PALS1_CANLF Protein PALS1 OS=Canis lupus familiaris
OX=9615 GN=PALS1 PE=1 SV=1
Length=675
Score = 1383 bits (3579), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 663/675 (98%), Positives = 672/675 (99%), Gaps = 0/675 (0%)
Query 1 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR 60
MTTSHMNGHVTEESD+EVKNVDLASPEEHQKHREMAVDCPGDLGTRMMP+RRSAQLERIR
Sbjct 1 MTTSHMNGHVTEESDNEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPVRRSAQLERIR 60
Query 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK 120
QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNP+FDTEEGIVLESPHYAVK
Sbjct 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPIFDTEEGIVLESPHYAVK 120
Query 121 ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF 180
ILE+EDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNA+TVHMNKASPPF
Sbjct 121 ILEVEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAVTVHMNKASPPF 180
Query 181 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE 240
PLISNAQDLAQEVQTVLKPVHHKEGQELTALL+ PH+QALLLAHDKVAEQEMQLEP TDE
Sbjct 181 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLSAPHVQALLLAHDKVAEQEMQLEPFTDE 240
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE
Sbjct 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD
Sbjct 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
Query 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
DPYVPCRELGLSFQKGDILH+ISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK
Sbjct 361 DPYVPCRELGLSFQKGDILHIISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
Query 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR
Sbjct 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRD EVAGRDYHFVSRQAFEADI
Sbjct 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDHEVAGRDYHFVSRQAFEADI 540
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP
Sbjct 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN
Sbjct 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
Query 661 KLDTEPQWVPSTWLR 675
KLDTEPQWVPS+WLR
Sbjct 661 KLDTEPQWVPSSWLR 675
>sp|B4F7E7|PALS1_RAT Protein PALS1 OS=Rattus norvegicus OX=10116
GN=Pals1 PE=1 SV=1
Length=675
Score = 1362 bits (3524), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 654/675 (97%), Positives = 665/675 (99%), Gaps = 0/675 (0%)
Query 1 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR 60
MTTS+MNGHVTEESDS +KN+ LASPEEH KHREMAVDCPGDLGTR+MP+RRSAQLERIR
Sbjct 1 MTTSYMNGHVTEESDSGIKNLGLASPEEHPKHREMAVDCPGDLGTRLMPVRRSAQLERIR 60
Query 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK 120
QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNP+FDTEEGIVLESPHYAVK
Sbjct 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPIFDTEEGIVLESPHYAVK 120
Query 121 ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF 180
ILE+EDLFSSLKHIQHTLVDSQSQEDISLLLQLVQN+DFQNAFKIHNA+TVHMNKASPPF
Sbjct 121 ILEVEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNRDFQNAFKIHNAVTVHMNKASPPF 180
Query 181 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE 240
PLI+N QDL QEVQTVLKPVH KEGQELTALLN PHIQALLLAHDKVAEQEMQLEPITDE
Sbjct 181 PLIANVQDLVQEVQTVLKPVHQKEGQELTALLNAPHIQALLLAHDKVAEQEMQLEPITDE 240
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
RVYESIG YGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE
Sbjct 241 RVYESIGHYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD
Sbjct 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
Query 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK
Sbjct 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
Query 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR
Sbjct 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTR+RRD EVAGRDYHFVSRQAFEADI
Sbjct 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRNRRDHEVAGRDYHFVSRQAFEADI 540
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR QSLKTLRNSDLKPYIIFIAPP
Sbjct 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRAQSLKTLRNSDLKPYIIFIAPP 600
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN
Sbjct 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
Query 661 KLDTEPQWVPSTWLR 675
KLDTEPQWVPSTWLR
Sbjct 661 KLDTEPQWVPSTWLR 675
>sp|Q9JLB2|PALS1_MOUSE Protein PALS1 OS=Mus musculus OX=10090
GN=Pals1 PE=1 SV=1
Length=675
Score = 1361 bits (3522), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 653/675 (97%), Positives = 666/675 (99%), Gaps = 0/675 (0%)
Query 1 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR 60
MTTS+MNGHVTEESDS +KN+DLASPEE+ KHREMAVDCPGDLGTRMMP+RRSAQLERIR
Sbjct 1 MTTSYMNGHVTEESDSGIKNLDLASPEEYPKHREMAVDCPGDLGTRMMPVRRSAQLERIR 60
Query 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK 120
QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNP+FDTEEGIVLESPHYAV
Sbjct 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPIFDTEEGIVLESPHYAVN 120
Query 121 ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF 180
IL++EDLFSSLKHIQHTLVDSQSQEDISLLLQLVQN+DFQNAFKIHNA+TVHM+KASPPF
Sbjct 121 ILDVEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNRDFQNAFKIHNAVTVHMSKASPPF 180
Query 181 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE 240
PLI+N QDL QEVQTVLKPVH KEGQELTALLN PHIQALLLAHDKVAEQEMQLEPITDE
Sbjct 181 PLIANVQDLVQEVQTVLKPVHQKEGQELTALLNAPHIQALLLAHDKVAEQEMQLEPITDE 240
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
RVYESIG YGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE
Sbjct 241 RVYESIGHYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD
Sbjct 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
Query 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK
Sbjct 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
Query 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR
Sbjct 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTR+RRD EVAGRDYHFVSRQAFEADI
Sbjct 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRNRRDHEVAGRDYHFVSRQAFEADI 540
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP
Sbjct 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN
Sbjct 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
Query 661 KLDTEPQWVPSTWLR 675
KLDTEPQWVPSTWLR
Sbjct 661 KLDTEPQWVPSTWLR 675
>sp|Q8JHF4|PAL1A_DANRE Protein PALS1 OS=Danio rerio OX=7955 GN=pals1a
PE=1 SV=2
Length=677
Score = 1009 bits (2609), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 517/681 (76%), Positives = 581/681 (85%), Gaps = 10/681 (1%)
Query 1 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR 60
MTTSHMNG+VTE D+ E Q+HREMAVDCP +LG R +P+RRSAQLE+IR
Sbjct 1 MTTSHMNGYVTESDGG--GGTDIVE-EGVQRHREMAVDCPSELGARTLPVRRSAQLEKIR 57
Query 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIV-----LESP 115
QQQED RRR EE +QELDLNSSMRLKKL+Q PK GIDNP F+ EG L+S
Sbjct 58 QQQEDRRRREEEGRSRQELDLNSSMRLKKLSQ-NPKVGIDNPTFEQMEGPGGSAGGLQSL 116
Query 116 HYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNK 175
+LE+EDL SLK +QH+L DSQSQED+ L+LQLVQ DFQ AF IHN++ +MN+
Sbjct 117 IAPPALLELEDLLMSLKQVQHSLNDSQSQEDVELVLQLVQKPDFQKAFSIHNSVAHYMNR 176
Query 176 ASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLE 235
SPP+PL +AQ LAQEV+ +++ HKEG EL++LL+T H+QAL++AHD VAEQEMQLE
Sbjct 177 PSPPYPLTDHAQTLAQEVEVMVQNSSHKEGLELSSLLSTSHMQALMMAHDSVAEQEMQLE 236
Query 236 PITDE-RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGL 294
P+ E++ Q+GGETVKIVRIEKA+DIPLGATVRN+MDSV+ISRIVKGGAAE+SGL
Sbjct 237 PLVPSVNASETLTQWGGETVKIVRIEKAKDIPLGATVRNDMDSVVISRIVKGGAAERSGL 296
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHF 354
LHEGDE+LEING+EIRGKDVNEVFD+L+DMHG L+FVLIPS QIK PP KETV+HVKAHF
Sbjct 297 LHEGDEILEINGVEIRGKDVNEVFDILADMHGVLSFVLIPSAQIKSPPIKETVVHVKAHF 356
Query 355 DYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ 414
DYDPSDDPYVPCRELGL FQKGDILH+ISQ+DPNWWQAYR+GDEDNQPLAGLVPGKSFQQ
Sbjct 357 DYDPSDDPYVPCRELGLCFQKGDILHIISQDDPNWWQAYRDGDEDNQPLAGLVPGKSFQQ 416
Query 415 QREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQ 474
QREAMKQTIEEDKEPEK+GKLWCAKK KKKRKK+ YNANKNDD+DNEEILTYEEM+LYHQ
Sbjct 417 QREAMKQTIEEDKEPEKTGKLWCAKKTKKKRKKMQYNANKNDDFDNEEILTYEEMALYHQ 476
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
PANRKRPI LIGP NCGQNELRQRL++ E DRFA VPHTTRSRRD E GRDYHFVSRQ
Sbjct 477 PANRKRPIALIGPPNCGQNELRQRLLSTEPDRFAGPVPHTTRSRRDAEANGRDYHFVSRQ 536
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
AFE D AAGKFIE GEFEKN YGTS DSVRQVIN+GKICLL + TQSLK LR+SDLKPYI
Sbjct 537 AFEMDSAAGKFIESGEFEKNFYGTSTDSVRQVINTGKICLLCVHTQSLKVLRSSDLKPYI 596
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFIAPPSQERLRALLAK+ KNPKPEELR+IIEK REMEQN GH FD AIVN+DLDK+YQE
Sbjct 597 IFIAPPSQERLRALLAKDNKNPKPEELRDIIEKAREMEQNYGHLFDAAIVNTDLDKSYQE 656
Query 655 LLRLINKLDTEPQWVPSTWLR 675
LLRLINKLDTEPQWVPS+WLR
Sbjct 657 LLRLINKLDTEPQWVPSSWLR 677
>sp|Q8BVD5|MPP7_MOUSE MAGUK p55 subfamily member 7 OS=Mus musculus
OX=10090 GN=Mpp7 PE=1 SV=2
Length=576
Score = 394 bits (1011), Expect = 3e-128, Method: Compositional matrix adjust.
Identities = 224/561 (40%), Positives = 333/561 (59%), Gaps = 46/561 (8%)
Query 143 SQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQ----DLAQEVQTVLK 198
SQED++ L + K + KIH + H + P P++ A DL +E+Q L
Sbjct 31 SQEDLTFLWDVFGEKSLHSLVKIHEKL--HCYEKQNPLPILHGAAALADDLTEELQNKLP 88
Query 199 PVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQ--LEPITDERVYESIGQYGGETVKI 256
+ E +EL LL+ P+++ALL HD VA++ L P+ D+ E ++VKI
Sbjct 89 ---NSEIRELLKLLSKPNVKALLSVHDTVAQKSYDPVLPPVPDDIDDEE------DSVKI 139
Query 257 VRIEKARDIPLGATVRN--EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
+R+ K + PLGAT++ + ++ ++RI++GGAA++SGL+H GDE+ E+NGI + K
Sbjct 140 IRLVKNSE-PLGATIKKDEQTGAITVARIMRGGAADRSGLIHVGDELREVNGIPVEDKRP 198
Query 315 NEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQ 374
E+ +LS G +TF +IPS + + P+KE I +KA FDYDP +D +PC+E GLSF+
Sbjct 199 EEIIKILSQSKGAITFKIIPSTK-EETPSKEGKIFIKALFDYDPKEDKAIPCKEAGLSFR 257
Query 375 KGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQ--------TIEED 426
KGDIL ++SQ+D WWQA EGD + P AGL+P K FQ++R A+++ +
Sbjct 258 KGDILQIMSQDDVTWWQAKHEGDAN--PRAGLIPSKHFQERRLALRRPEIVVQPLKLSNT 315
Query 427 KEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYH-QPANRKRPIILI 485
K ++KNKK K +Y K++ YD ++ TYEE++ Y Q ++ R I+L+
Sbjct 316 KSSGFRRSFRLSRKNKKINKS-MYECKKSEQYDTADVPTYEEVTPYRRQIHDKYRLIVLV 374
Query 486 GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKF 545
GP G NEL+++L+ + + VPHTTR+RR QE G +Y F+S+ FE D+ KF
Sbjct 375 GPVGVGLNELKRKLLMSDAQHYGVIVPHTTRARRSQESDGVEYIFISKHLFETDVQINKF 434
Query 546 IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERL 605
IE+GE++ N YGTSIDSVR V+ K+CLL ++ ++K LR + KPY+IFI PPS ERL
Sbjct 435 IEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERL 494
Query 606 RALLAKEGK---------NPKP---EELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
R K K KP E+ +E+I+ + ME GH FD I+N DL A+
Sbjct 495 RE-TRKNAKIISSRDDQGTAKPFTEEDFQEMIKSAQIMESQYGHLFDKIIINDDLTVAFN 553
Query 654 ELLRLINKLDTEPQWVPSTWL 674
EL +KL+T+ WVP +WL
Sbjct 554 ELKTTFDKLETDTHWVPVSWL 574
>sp|A8KBF6|MPP7_XENTR MAGUK p55 subfamily member 7 OS=Xenopus
tropicalis OX=8364 GN=mpp7 PE=2 SV=1
Length=576
Score = 392 bits (1007), Expect = 2e-127, Method: Compositional matrix adjust.
Identities = 226/557 (41%), Positives = 341/557 (61%), Gaps = 38/557 (7%)
Query 143 SQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVH- 201
SQED++ L + K + KIH + H + P P+I +A LA+E+ L+
Sbjct 31 SQEDLTFLWDMFGEKSLHSLVKIHEKL--HYYEKENPMPVIHSATALAEELAEELQSKSL 88
Query 202 HKEGQELTALLNTPHIQALLLAHDKVAEQEMQ--LEPITDERVYESIGQYGGETVKIVRI 259
+ E +EL LL+ P+++ALL HD VA++ L P+ D+ + ++VKI+R+
Sbjct 89 NSEIRELLKLLSKPNLKALLSVHDTVAQKSYDPVLPPMPDDIDDDE------DSVKIIRL 142
Query 260 EKARDIPLGATVRNE--MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
K R+ PLGAT++ + +++++RI++GGAA++SGL+H GDE+ E+NGI + K E+
Sbjct 143 VKNRE-PLGATIKKDEKTGAIVVARIMRGGAADRSGLIHVGDELREVNGISVEDKKPEEI 201
Query 318 FDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGD 377
+L+ G +TF +IPS + + PP + + VKA FDY P++D +PC+E GLSF+KGD
Sbjct 202 IHILAQSQGAITFKIIPSIK-EEPPNNDGKMFVKALFDYYPNEDKAIPCKEAGLSFRKGD 260
Query 378 ILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEK------ 431
IL ++SQ+D WWQA EGD + P AGL+P K FQ++R A+++ + + +P+K
Sbjct 261 ILQIMSQDDATWWQAKHEGDAN--PRAGLIPSKQFQERRFALRKPVVSN-QPQKVPNRKS 317
Query 432 SGKLWCAKKNKKKRK--KVLYNANKNDDYDNEEILTYEEMSLYHQPANRK-RPIILIGPQ 488
SG + ++K RK K +Y K+D YD ++ TYEE++LY + N K R +IL+GP
Sbjct 318 SGFRRSFRLSRKDRKTNKFMYECKKSDQYDTADVPTYEEVALYQRKPNEKYRLVILVGPV 377
Query 489 NCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEH 548
G NEL+++++ + VPHTTR +R QE G +Y F+S+ FE DI KFIE+
Sbjct 378 GVGVNELKRKVLIGNSQHYGVTVPHTTRGKRSQENDGVEYIFISKHLFETDIHNNKFIEY 437
Query 549 GEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLR-- 606
GE++ N YGTS+DSVR V+ KICLL ++ SLK LR S+ KP++IFI PP+ ERLR
Sbjct 438 GEYKNNYYGTSLDSVRSVLAKNKICLLDVQPNSLKHLRTSEFKPFVIFIKPPTIERLRET 497
Query 607 -----ALLAKEGKN-PKP---EELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
+ K+ + KP E+ E+I+ ME H+FDT IVN DL AY EL
Sbjct 498 RRNAKVISGKDERGAAKPFSDEDFEEMIQSAEAMEAQYDHFFDTTIVNDDLSAAYNELRS 557
Query 658 LINKLDTEPQWVPSTWL 674
+ +L+ E WVP +WL
Sbjct 558 TLERLEMEGFWVPVSWL 574
>sp|Q6P0D7|MPP7_DANRE MAGUK p55 subfamily member 7 OS=Danio rerio
OX=7955 GN=mpp7 PE=1 SV=1
Length=576
Score = 383 bits (983), Expect = 6e-124, Method: Compositional matrix adjust.
Identities = 213/556 (38%), Positives = 337/556 (61%), Gaps = 36/556 (6%)
Query 142 QSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKP-V 200
+S +D S L + + + KIH + + + A P P++ +A LA ++ L+
Sbjct 30 ESPDDRSFLHAMFGERSLHSLVKIHEKLQCYEDCA--PTPVLDSAGSLAADLTEELQARS 87
Query 201 HHKEGQELTALLNTPHIQALLLAHDKVAEQEM--QLEPITDERVYESIGQYGGETVKIVR 258
E +EL LL+ PH+++LL HD VA++ +L P+ D+ E ++VKI+R
Sbjct 88 ASNEIRELVKLLSKPHVKSLLSVHDTVAKKSYDPELPPLPDDIDDEE------DSVKIIR 141
Query 259 IEKARDIPLGATVRNE--MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
+ K ++ PLGAT++ + +++++RI++GGAA++SGL+H GDE+ E+NGI + K E
Sbjct 142 LVKNKE-PLGATIKKDEHTGAILVARILRGGAADRSGLIHVGDELKEVNGIPVDDKKPEE 200
Query 317 VFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKG 376
+ +LS G +TF ++P + +KE + +KA FDY+P++D +PC+E GL F+KG
Sbjct 201 IIRILSQSQGAITFKVVPGIK-DEAQSKEPKMFIKALFDYNPAEDKAIPCKEAGLGFKKG 259
Query 377 DILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQ-----TIEEDKEPEK 431
DIL V+SQ+D WWQA EGD + + AGL+P K FQ++R A+ + T++
Sbjct 260 DILQVMSQDDATWWQAKLEGDGNLR--AGLIPSKHFQERRLAVWRPTPVMTLQRTSSKRF 317
Query 432 SGKLWCAKKNK--KKRKKVLYNANKNDDYDNEEILTYEEMSLYHQP-ANRKRPIILIGPQ 488
SG + ++ KK K +Y K++ YD ++ TYEE++ Y + +R R ++L+GP
Sbjct 318 SGLRRSFRLSRRDKKTNKSMYECKKSEQYDTADVPTYEEVTTYRRKHGDRHRLVVLVGPT 377
Query 489 NCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEH 548
G NEL+++L+ + F+ +PHT+RS+R QE G +YHF+S+ FEADI KFIEH
Sbjct 378 GVGLNELKRKLLISDTQHFSVTIPHTSRSKRHQESEGVEYHFISKNLFEADIQNNKFIEH 437
Query 549 GEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRAL 608
GE++ N YGTS DSVR V++ K+CLL ++ +LK LR ++ KPY++F+ PP ERLR
Sbjct 438 GEYKGNYYGTSFDSVRSVLSKNKVCLLDVQPHTLKHLRTAEFKPYVVFVKPPCIERLRET 497
Query 609 L--AK--EGKNPKP-------EELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
AK GK+ K E+ E+I ++ ME GH F+ IVN DL A+ EL +
Sbjct 498 RRNAKVISGKDDKTSSKAFSEEDFLEMISASQMMENQYGHLFEKVIVNDDLTVAFSELKQ 557
Query 658 LINKLDTEPQWVPSTW 673
+ K++TE WVP +W
Sbjct 558 ALKKVETEAHWVPISW 573
>sp|Q5U2Y3|MPP7_RAT MAGUK p55 subfamily member 7 OS=Rattus norvegicus
OX=10116 GN=Mpp7 PE=2 SV=2
Length=576
Score = 370 bits (949), Expect = 6e-119, Method: Compositional matrix adjust.
Identities = 226/559 (40%), Positives = 336/559 (60%), Gaps = 42/559 (8%)
Query 143 SQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVL--KPV 200
SQED++ L + K + KIH + H + P P++ A LA ++ L KP
Sbjct 31 SQEDLTFLWDMFGEKSLHSLVKIHEKL--HYYEKQSPVPILHGAAALADDLADELQNKPP 88
Query 201 HHKEGQELTALLNTPHIQALLLAHDKVAEQEMQ--LEPITDERVYESIGQYGGETVKIVR 258
+ E +EL LL+ P+++ALL HD VA++ L P+ D+ E ++VKI+R
Sbjct 89 N-SEIRELLKLLSKPNVKALLSVHDTVAQKSYDPVLPPMPDDIDDEE------DSVKIIR 141
Query 259 IEKARDIPLGATVRN--EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
+ K R+ PLGAT++ + ++ ++RI++GGAA++SGL+H GDE+ E+NGI + K E
Sbjct 142 LVKNRE-PLGATIKKDEQTGAITVARIMRGGAADRSGLIHVGDELREVNGIPVEDKRPEE 200
Query 317 VFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKG 376
+ +LS G +TF +IPS + + P+KE I +KA FDYDP +D +PC+E GLSF+KG
Sbjct 201 IIQILSQSQGAITFKIIPSTK-EEIPSKEGKIFIKALFDYDPKEDKAIPCKEAGLSFRKG 259
Query 377 DILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEK----- 431
DIL ++SQ+D WWQA EGD P AGL+P K FQ++R A+++ E +P K
Sbjct 260 DILQIMSQDDATWWQAKHEGD--TNPRAGLIPSKHFQERRLALRRP-EIVVQPLKLSNRK 316
Query 432 -SG--KLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYH-QPANRKRPIILIGP 487
SG + + + KK K +Y K++ YD ++ TYEE++ Y Q ++ R ++L+GP
Sbjct 317 SSGFRRSFRLSRKDKKTNKSMYECKKSEQYDTADVPTYEEVTPYRRQTHDKYRLVVLVGP 376
Query 488 QNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIE 547
G NEL+++L+ + + VPHTTR+RR QE G +Y F+S+ FE D+ KFIE
Sbjct 377 VGVGLNELKRKLLMSDTQHYGVTVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIE 436
Query 548 HGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRA 607
+GE++ N YGTSIDSVR V+ K+CLL ++ ++K LR + KPY+IFI PPS ERLR
Sbjct 437 YGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERLRE 496
Query 608 LLAKEGK---------NPKP---EELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
K K KP E+ +E+I+ + ME GH FD I+N DL A+ EL
Sbjct 497 -TRKNAKIISSRDDQGTAKPFTEEDFQEMIKSAQIMESQYGHLFDKIIINDDLTVAFNEL 555
Query 656 LRLINKLDTEPQWVPSTWL 674
+KL+T+ WVP +WL
Sbjct 556 KTTFDKLETDAHWVPVSWL 574
>sp|Q5T2T1|MPP7_HUMAN MAGUK p55 subfamily member 7 OS=Homo sapiens
OX=9606 GN=MPP7 PE=1 SV=1
Length=576
Score = 370 bits (949), Expect = 7e-119, Method: Compositional matrix adjust.
Identities = 223/558 (40%), Positives = 341/558 (61%), Gaps = 40/558 (7%)
Query 143 SQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVL--KPV 200
SQED++ L + K + KIH + H + P P++ A LA ++ L KP+
Sbjct 31 SQEDLTFLWDMFGEKSLHSLVKIHEKL--HYYEKQSPVPILHGAAALADDLAEELQNKPL 88
Query 201 HHKEGQELTALLNTPHIQALLLAHDKVAEQEMQ--LEPITDERVYESIGQYGGETVKIVR 258
+ E +EL LL+ P+++ALL HD VA++ L P+ ++ E ++VKI+R
Sbjct 89 N-SEIRELLKLLSKPNVKALLSVHDTVAQKNYDPVLPPMPEDIDDEE------DSVKIIR 141
Query 259 IEKARDIPLGATVRN--EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
+ K R+ PLGAT++ + ++I++RI++GGAA++SGL+H GDE+ E+NGI + K E
Sbjct 142 LVKNRE-PLGATIKKDEQTGAIIVARIMRGGAADRSGLIHVGDELREVNGIPVEDKRPEE 200
Query 317 VFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKG 376
+ +L+ G +TF +IP + + P+KE + +KA FDY+P++D +PC+E GLSF+KG
Sbjct 201 IIQILAQSQGAITFKIIPGSK-EETPSKEGKMFIKALFDYNPNEDKAIPCKEAGLSFKKG 259
Query 377 DILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEK----- 431
DIL ++SQ+D WWQA E D + P AGL+P K FQ++R A+++ E +P K
Sbjct 260 DILQIMSQDDATWWQAKHEADAN--PRAGLIPSKHFQERRLALRRP-EILVQPLKVSNRK 316
Query 432 -SG--KLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRK-RPIILIGP 487
SG K + + KK K +Y K+D YD ++ TYEE++ Y + N K R ++L+GP
Sbjct 317 SSGFRKSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGP 376
Query 488 QNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIE 547
G NEL+++L+ + + VPHTTR+RR QE G +Y F+S+ FE D+ KFIE
Sbjct 377 VGVGLNELKRKLLISDTQHYGVTVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIE 436
Query 548 HGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLR- 606
+GE++ N YGTSIDSVR V+ K+CLL ++ ++K LR + KPY+IFI PPS ERLR
Sbjct 437 YGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERLRE 496
Query 607 ------ALLAKEGKN-PKP---EELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+ +++ + KP E+ +E+I+ + ME GH FD I+N DL A+ EL
Sbjct 497 TRKNAKIISSRDDQGAAKPFTEEDFQEMIKSAQIMESQYGHLFDKIIINDDLTVAFNELK 556
Query 657 RLINKLDTEPQWVPSTWL 674
+KL+TE WVP +WL
Sbjct 557 TTFDKLETETHWVPVSWL 574
>sp|A6QQZ7|MPP7_BOVIN MAGUK p55 subfamily member 7 OS=Bos taurus
OX=9913 GN=MPP7 PE=2 SV=1
Length=576
Score = 369 bits (947), Expect = 1e-118, Method: Compositional matrix adjust.
Identities = 219/558 (39%), Positives = 339/558 (61%), Gaps = 40/558 (7%)
Query 143 SQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVL--KPV 200
SQED++ L + K + KIH + H + P P++ A LA ++ L KP+
Sbjct 31 SQEDLTFLWDVFGEKSLHSLVKIHEKL--HYYEKQNPVPILQGAAALADDLAEELQNKPL 88
Query 201 HHKEGQELTALLNTPHIQALLLAHDKVAEQEMQ--LEPITDERVYESIGQYGGETVKIVR 258
+ E +EL LL+ P+++ALL HD VA++ L P+ D+ E ++VKI+R
Sbjct 89 N-SEIRELLKLLSKPNVKALLSVHDTVAQKNYDPVLPPMPDDIDNEE------DSVKIIR 141
Query 259 IEKARDIPLGATVRN--EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
+ K R+ PLGAT++ + +++++RI++GGAA++SGL+H GDE+ E+NGI + K E
Sbjct 142 LVKNRE-PLGATIKKDEQTGAIVVARIMRGGAADRSGLIHVGDELREVNGIPVEDKRPEE 200
Query 317 VFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKG 376
+ +L+ G +TF +IPS + + P+KE + +KA FDYDP++D +PC+E GLSF+KG
Sbjct 201 IIQILAQSQGAITFKIIPSIK-EETPSKEGKMFIKALFDYDPNEDKAIPCKEAGLSFKKG 259
Query 377 DILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQ--------TIEEDKE 428
DIL ++SQ+D WWQA EGD + P AGL+P K FQ++R A+++ + K
Sbjct 260 DILQIMSQDDATWWQAKHEGDAN--PRAGLIPSKHFQERRLALRRPEILVQPLKVSSRKS 317
Query 429 PEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRK-RPIILIGP 487
++K+KK K +Y ++D YD ++ TYEE++ Y + N K R ++L+GP
Sbjct 318 SGFRRSFRLSRKDKKTNKS-MYECKRSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGP 376
Query 488 QNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIE 547
G NEL+++L+ + + VPHTTR RR QE G +Y F+S+ FE D+ KFIE
Sbjct 377 VGVGLNELKRKLLISDTQHYGVTVPHTTRPRRSQESDGVEYIFISKHLFETDVQNNKFIE 436
Query 548 HGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLR- 606
+GE++ N YGTSIDSVR V+ K+CLL ++ ++K LR + KP++IFI PPS ERLR
Sbjct 437 YGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFKPFVIFIKPPSIERLRE 496
Query 607 ------ALLAKEGKN-PKP---EELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+ +++ + KP ++ +E+I+ + ME GH FD IVN DL A+ EL
Sbjct 497 TRKNAKIISSRDDQGAAKPFTEDDFQEMIKSAQIMESQYGHLFDKTIVNDDLAVAFNELK 556
Query 657 RLINKLDTEPQWVPSTWL 674
+KL+T+ WVP +WL
Sbjct 557 TTFDKLETDTHWVPVSWL 574
>sp|Q13368|MPP3_HUMAN MAGUK p55 subfamily member 3 OS=Homo sapiens
OX=9606 GN=MPP3 PE=1 SV=2
Length=585
Score = 353 bits (905), Expect = 3e-112, Method: Compositional matrix adjust.
Identities = 202/577 (35%), Positives = 333/577 (58%), Gaps = 56/577 (10%)
Query 140 DSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKP 199
DS +E++ L + K KIH + + ++ P P++ +A LA++V L+
Sbjct 24 DSNHKEEMGFLRDVFSEKSLSYLMKIHEKLRYYERQS--PTPVLHSAVALAEDVMEELQA 81
Query 200 VH-HKEGQELTALLNTPHIQALLLAHDKVAEQEMQ--LEPITDERVYESIGQYGGETVKI 256
H + +EL LL+TPH++A+L+ HD VA++ L P+ D + E + E+VKI
Sbjct 82 ASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDN-IDEDFDE---ESVKI 137
Query 257 VRIEKARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
VR+ K ++ PLGAT+R + S V+++RI++GGAA++SGL+H GDE+ E+NGI + K
Sbjct 138 VRLVKNKE-PLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRP 196
Query 315 NEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQ 374
+E+ +L+ G++T +IP+ Q + KE+ + ++A F Y+P +D +PC+E GL FQ
Sbjct 197 DEISQILAQSQGSITLKIIPATQ-EEDRLKESKVFMRALFHYNPREDRAIPCQEAGLPFQ 255
Query 375 KGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPE---- 430
+ +L V+SQ+DP WWQA R GD + + AGL+P K FQ++R + ++ P+
Sbjct 256 RRQVLEVVSQDDPTWWQAKRVGDTNLR--AGLIPSKGFQERRLSYRRAAGTLPSPQSLRK 313
Query 431 ---------------------------KSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEI 463
+S +L C ++R + ++ E+
Sbjct 314 PPYDQPCDKETCDCEGYLKGHYVAGLRRSFRLGC-----RERLGGSQEGKMSSGAESPEL 368
Query 464 LTYEEMSLY-HQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQE 522
LTYEE++ Y HQP R R ++LIG +EL+Q+++ + F AVPHTTR R+ E
Sbjct 369 LTYEEVARYQHQPGERPRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHE 428
Query 523 VAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSL 582
G +YHFVS+QAFEAD+ KF+EHGE+++NLYGTS+++++ V+ K+CL+ + ++L
Sbjct 429 KEGVEYHFVSKQAFEADLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEAL 488
Query 583 KTLRNSDLKPYIIFIAPPSQERLR----ALLAKEGKNPKPEELREIIEKTREMEQNNGHY 638
K LR S+ KPYIIF+ P QE+ + + ++ P E+ +E+ ++++ GH
Sbjct 489 KQLRTSEFKPYIIFVKPAIQEKRKTPPMSPACEDTAAPFDEQQQEMAASAAFIDRHYGHL 548
Query 639 FDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWLR 675
D +V DL AY +L ++ KL + WVP +W+R
Sbjct 549 VDAVLVKEDLQGAYSQLKVVLEKLSKDTHWVPVSWVR 585
>sp|Q9JLB0|PALS2_MOUSE Protein PALS2 OS=Mus musculus OX=10090
GN=Pals2 PE=1 SV=1
Length=553
Score = 351 bits (900), Expect = 6e-112, Method: Compositional matrix adjust.
Identities = 188/488 (39%), Positives = 291/488 (60%), Gaps = 34/488 (7%)
Query 207 ELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIG-QYGGETVKIVRIEKARDI 265
EL +L PH Q+LL AHD VA + P + E S+ Q + ++I+ I K
Sbjct 79 ELVGILKEPHFQSLLEAHDIVASKCYDSPPSSPEMNIPSLNNQLPVDAIRILGIHKKAGE 138
Query 266 PLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMH 325
PLG T R E + ++I+RI+ GG ++ GLLH GD + E+NG E+ G + E+ +LL ++
Sbjct 139 PLGVTFRVENNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEV-GNNPKELQELLKNIS 197
Query 326 GTLTFVLIPSQQ--IKPP---------PAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQ 374
G++T ++PS + I P PA + VK HFDY+P +D +PC+E GL F
Sbjct 198 GSVTLKILPSYRDTITPQQSYVNMERHPAHVRQVFVKCHFDYNPFNDNLIPCKEAGLKFS 257
Query 375 KGDILHVISQEDPNWWQA--YREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKS 432
KG+IL ++++EDPNWWQA +EG AGL+P + +++R+A + ++ P
Sbjct 258 KGEILQIVNREDPNWWQASHVKEGGS-----AGLIPSQFLEEKRKAFVRRDWDNSGP--- 309
Query 433 GKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQ 492
+C + KK+KK++Y +N ++D EI YEE++ P +++ ++LIG Q G+
Sbjct 310 ---FCGTISNKKKKKMMYLTTRNAEFDRHEIQIYEEVA--KMPPFQRKTLVLIGAQGVGR 364
Query 493 NELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFE 552
L+ R + RF + VP T+R R+ E G+ Y FVSR EADI AGK++EHGE+E
Sbjct 365 RSLKNRFIVLNPARFGTTVPFTSRKPREDEKDGQAYKFVSRSEMEADIKAGKYLEHGEYE 424
Query 553 KNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRAL---L 609
NLYGT IDS+ +V+ +G+ C+L + Q+LK LR S+ PY++FIA P E LRA+ +
Sbjct 425 GNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAAPELETLRAMHKAV 484
Query 610 AKEGKNPK---PEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEP 666
G K +L++ ++++ +++ HYFD IVN +LDKA+++L I KL EP
Sbjct 485 VDAGITTKLLTDSDLKKTVDESARIQRAYNHYFDLIIVNDNLDKAFEKLQTAIEKLRMEP 544
Query 667 QWVPSTWL 674
QWVP +W+
Sbjct 545 QWVPISWV 552
>sp|O88954|MPP3_RAT MAGUK p55 subfamily member 3 OS=Rattus norvegicus
OX=10116 GN=Mpp3 PE=1 SV=3
Length=585
Score = 350 bits (897), Expect = 4e-111, Method: Compositional matrix adjust.
Identities = 204/579 (35%), Positives = 335/579 (58%), Gaps = 60/579 (10%)
Query 140 DSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKP 199
DS +E++ L + K KIH + + ++ P P++ +A LA++V L+
Sbjct 24 DSNHREEMGFLRDVFSEKSLGYLMKIHEKLRYYERQS--PTPVLHSAMALAEDVMEELQA 81
Query 200 VH-HKEGQELTALLNTPHIQALLLAHDKVAEQEMQ--LEPITDERVYESIGQ-YGGETVK 255
H + +EL LL+TPH++A+L+ HD VA++ L P+ D +I + + E+VK
Sbjct 82 ASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPD-----NIDEDFEEESVK 136
Query 256 IVRIEKARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
IVR+ K ++ PLGAT+R + S V+++RI++GGAA++SGL+H GDE+ E+NGI + K
Sbjct 137 IVRLVKNKE-PLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGITVLHKR 195
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSF 373
+E+ +L+ G++T +IP+ Q + KE+ + ++A F YDP +D +PC+E GL F
Sbjct 196 PDEISQILAQSQGSITLKIIPATQ-EEDRFKESKVFMRALFHYDPREDRAIPCQEAGLPF 254
Query 374 QKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPE--- 430
Q+ +L V+SQ+DP WWQA R GD + + AGL+P K FQ++R + ++T P+
Sbjct 255 QQRQVLEVVSQDDPTWWQAKRVGDTNLR--AGLIPSKQFQERRLSYRRTTGTIPSPQNLR 312
Query 431 ----------------------------KSGKLWCAKK-NKKKRKKVLYNANKNDDYDNE 461
+S +L C ++ + KV A +++
Sbjct 313 KPLYDQPCDKETCDCDGYFKGHYVAGLRRSFRLGCRERLTGSQEVKVPVGA------ESQ 366
Query 462 EILTYEEMSLY-HQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRD 520
+LTYEE++ Y HQP R R ++LIG +EL+QR++ ++ F AVPHTTR R+
Sbjct 367 VLLTYEEVARYQHQPGERSRLVVLIGSLGAHLHELKQRVVAEDPQHFGVAVPHTTRPRKS 426
Query 521 QEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQ 580
E G +YHFVS+QAFEADI KF+EHGE ++NLYGTS+++++ V+ K+CL+ + +
Sbjct 427 HEREGVEYHFVSKQAFEADIQHNKFLEHGEHKENLYGTSLEAIQTVMAKNKVCLVDVEPE 486
Query 581 SLKTLRNSDLKPYIIFIAPPSQERLR----ALLAKEGKNPKPEELREIIEKTREMEQNNG 636
+L+ LR + KPY+IF+ P QE+ + + +++ P E+ +E+ ++Q+ G
Sbjct 487 ALRHLRTPEFKPYVIFVKPAIQEKRKTPPVSPDSEDPATPLDEQQQEMAASAAFIDQHYG 546
Query 637 HYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWLR 675
H DT +V DL +L +I L + WVP +W+R
Sbjct 547 HLIDTVLVRQDLQSVCSQLRAVIESLSKDTYWVPISWVR 585
>sp|D3ZAA9|MPP2_RAT MAGUK p55 subfamily member 2 OS=Rattus norvegicus
OX=10116 GN=Mpp2 PE=1 SV=2
Length=552
Score = 346 bits (888), Expect = 3e-110, Method: Compositional matrix adjust.
Identities = 182/476 (38%), Positives = 284/476 (60%), Gaps = 22/476 (5%)
Query 207 ELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQ-YGGETVKIVRIEKARDI 265
EL +L PH Q+LL HD VA + + P + Q + V++V I K
Sbjct 90 ELARILQEPHFQSLLETHDSVASKTYETPPPSPGLDPTFSNQPVPPDAVRMVGIRKTAGE 149
Query 266 PLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMH 325
LG T R E ++I+RI+ GG + GLLH GD + E+NG + G D + +LL
Sbjct 150 HLGVTFRVEGGELVIARILHGGMVAQQGLLHVGDIIKEVNGQPV-GSDPRALQELLRSAS 208
Query 326 GTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE 385
G++ ++PS Q P + + VK HFDYDP+ D +PC+E GL F GD+L +++Q+
Sbjct 209 GSVILKILPSYQEPHLPRQ---VFVKCHFDYDPARDSLIPCKEAGLRFNAGDLLQIVNQD 265
Query 386 DPNWWQA-YREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKK 444
D NWWQA + EG AGL+P + +++R+A ++ D E + C + KK
Sbjct 266 DANWWQACHVEGGS-----AGLIPSQLLEEKRKAF---VKRDLELTPTSGTLCGSLSGKK 317
Query 445 RKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEK 504
+K+++Y KN ++D E+L YEE++ P R++ ++LIG Q G+ L+ +L+ +
Sbjct 318 KKRMMYLTTKNAEFDRHELLIYEEVA--RMPPFRRKTLVLIGAQGVGRRSLKNKLILWDP 375
Query 505 DRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVR 564
DR+ + VP+T+R +D E G+ Y FVSR EADI AG+++EHGE+E NLYGT IDS+R
Sbjct 376 DRYGTTVPYTSRRPKDSEREGQGYSFVSRGEMEADIRAGRYLEHGEYEGNLYGTRIDSIR 435
Query 565 QVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRAL---LAKEGKNPK---P 618
V+ SGK+C+L + Q++K LR ++ PY++FI P E LRA+ + G + K
Sbjct 436 GVVASGKVCVLDVNPQAVKVLRTAEFVPYVVFIEAPDFETLRAMNRAALESGVSTKQLTE 495
Query 619 EELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
+LR +E++ +++ GHYFD ++VNS+L++ ++EL + KL TEPQWVP +W+
Sbjct 496 ADLRRTVEESSRIQRGYGHYFDLSLVNSNLERTFRELQTAMEKLRTEPQWVPVSWV 551
>sp|Q14168|MPP2_HUMAN MAGUK p55 subfamily member 2 OS=Homo sapiens
OX=9606 GN=MPP2 PE=1 SV=3
Length=576
Score = 347 bits (890), Expect = 4e-110, Method: Compositional matrix adjust.
Identities = 186/495 (38%), Positives = 291/495 (59%), Gaps = 27/495 (5%)
Query 193 VQTVLKPVHHKEGQ-----ELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIG 247
VQ +L+ + H Q EL +L PH Q+LL HD VA + + P +
Sbjct 95 VQEILRDLAHVAEQSSTAAELAHILQEPHFQSLLETHDSVASKTYETPPPSPGLDPTFSN 154
Query 248 Q-YGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEING 306
Q + V++V I K LG T R E ++I+RI+ GG + GLLH GD + E+NG
Sbjct 155 QPVPPDAVRMVGIRKTAGEHLGVTFRVEGGELVIARILHGGMVAQQGLLHVGDIIKEVNG 214
Query 307 IEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPC 366
+ G D + +LL + G++ ++PS Q P + + VK HFDYDP+ D +PC
Sbjct 215 QPV-GSDPRALQELLRNASGSVILKILPSYQEPHLPRQ---VFVKCHFDYDPARDSLIPC 270
Query 367 RELGLSFQKGDILHVISQEDPNWWQA-YREGDEDNQPLAGLVPGKSFQQQREAMKQTIEE 425
+E GL F GD+L +++Q+D NWWQA + EG AGL+P + +++R+A ++
Sbjct 271 KEAGLRFNAGDLLQIVNQDDANWWQACHVEGGS-----AGLIPSQLLEEKRKAF---VKR 322
Query 426 DKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILI 485
D E + C + KK+K+++Y KN ++D E+L YEE++ P R++ ++LI
Sbjct 323 DLELTPNSGTLCGSLSGKKKKRMMYLTTKNAEFDRHELLIYEEVA--RMPPFRRKTLVLI 380
Query 486 GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKF 545
G Q G+ L+ +L+ + DR+ + VP+T+R +D E G+ Y FVSR EAD+ AG++
Sbjct 381 GAQGVGRRSLKNKLIMWDPDRYGTTVPYTSRRPKDSEREGQGYSFVSRGEMEADVRAGRY 440
Query 546 IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERL 605
+EHGE+E NLYGT IDS+R V+ +GK+C+L + Q++K LR ++ PY++FI P E L
Sbjct 441 LEHGEYEGNLYGTRIDSIRGVVAAGKVCVLDVNPQAVKVLRTAEFVPYVVFIEAPDFETL 500
Query 606 RAL--LAKEG----KNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
RA+ A E K +LR +E++ +++ GHYFD +VNS+L++ ++EL +
Sbjct 501 RAMNRAALESGISTKQLTEADLRRTVEESSRIQRGYGHYFDLCLVNSNLERTFRELQTAM 560
Query 660 NKLDTEPQWVPSTWL 674
KL TEPQWVP +W+
Sbjct 561 EKLRTEPQWVPVSWV 575
>sp|Q9WV34|MPP2_MOUSE MAGUK p55 subfamily member 2 OS=Mus musculus
OX=10090 GN=Mpp2 PE=1 SV=1
Length=552
Score = 345 bits (885), Expect = 9e-110, Method: Compositional matrix adjust.
Identities = 182/476 (38%), Positives = 283/476 (59%), Gaps = 22/476 (5%)
Query 207 ELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQ-YGGETVKIVRIEKARDI 265
EL +L PH Q+LL HD VA + + P + Q + V++V I K
Sbjct 90 ELARILQEPHFQSLLETHDSVASKTYETPPPSPGLDPTFSNQPVPPDAVRMVGIRKTAGE 149
Query 266 PLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMH 325
LG T R E ++I+RI+ GG + GLLH GD + E+NG + G D + +LL
Sbjct 150 HLGVTFRVEGGELVIARILHGGMVAQQGLLHVGDIIKEVNGQPV-GSDPRALQELLRSAS 208
Query 326 GTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE 385
G++ ++PS Q P + + VK HFDYDP+ D PC+E GL F GD+L +++Q+
Sbjct 209 GSVILKILPSYQEPHLPRQ---VFVKCHFDYDPARDSLSPCKEAGLRFNAGDLLQIVNQD 265
Query 386 DPNWWQA-YREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKK 444
D NWWQA + EG AGL+P + +++R+A ++ D E + C + KK
Sbjct 266 DANWWQACHVEGGS-----AGLIPSQLLEEKRKAF---VKRDLELTPTSGTLCGSLSGKK 317
Query 445 RKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEK 504
+K+++Y KN ++D E+L YEE++ P R++ ++LIG Q G+ L+ +L+ +
Sbjct 318 KKRMMYLTTKNAEFDRHELLIYEEVA--RMPPFRRKTLVLIGAQGVGRRSLKNKLILWDP 375
Query 505 DRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVR 564
DR+ + VP+T+R +D E G+ Y FVSR EADI AG+++EHGE+E NLYGT IDS+R
Sbjct 376 DRYGTTVPYTSRRPKDSEREGQGYSFVSRGEMEADIRAGRYLEHGEYEGNLYGTRIDSIR 435
Query 565 QVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRAL---LAKEGKNPK---P 618
V+ SGK+C+L + Q++K LR ++ PY++FI P E LRA+ + G + K
Sbjct 436 GVVASGKVCVLDVNPQAVKVLRTAEFVPYVVFIEAPDYETLRAMNRAALESGVSTKQLTE 495
Query 619 EELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
+LR +E++ +++ GHYFD ++VNS+L++ ++EL + KL TEPQWVP +W+
Sbjct 496 ADLRRTVEESSRIQRGYGHYFDLSLVNSNLERTFRELQTAMEKLRTEPQWVPVSWV 551
>sp|Q9NZW5|PALS2_HUMAN Protein PALS2 OS=Homo sapiens OX=9606 GN=PALS2
PE=1 SV=2
Length=540
Score = 338 bits (868), Expect = 2e-107, Method: Compositional matrix adjust.
Identities = 184/478 (38%), Positives = 288/478 (60%), Gaps = 27/478 (6%)
Query 207 ELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQ--YGGETVKIVRIEKARD 264
EL +L PH Q+LL AHD VA + P + E SI + ++I+ I K
Sbjct 79 ELVGILKEPHFQSLLEAHDIVASKCYDSPPSSPEMNNSSINNQLLPVDAIRILGIHKRAG 138
Query 265 IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
PLG T R E + ++I+RI+ GG ++ GLLH GD + E+NG E+ G + E+ +LL ++
Sbjct 139 EPLGVTFRVENNDLVIARILHGGMIDRQGLLHVGDIIKEVNGHEV-GNNPKELQELLKNI 197
Query 325 HGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ 384
G++T ++PS + P + + VK HFDY+P +D +PC+E GL F KG+IL ++++
Sbjct 198 SGSVTLKILPSYRDTITPQQ---VFVKCHFDYNPYNDNLIPCKEAGLKFSKGEILQIVNR 254
Query 385 EDPNWWQA--YREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNK 442
EDPNWWQA +EG AGL+P + +++R+A + ++ P +C +
Sbjct 255 EDPNWWQASHVKEGGS-----AGLIPSQFLEEKRKAFVRRDWDNSGP------FCGTISS 303
Query 443 KKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNK 502
KK+KK++Y +N ++D EI YEE++ P +++ ++LIG Q G+ L+ R +
Sbjct 304 KKKKKMMYLTTRNAEFDRHEIQIYEEVA--KMPPFQRKTLVLIGAQGVGRRSLKNRFIVL 361
Query 503 EKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDS 562
RF + VP T+R R+ E G+ Y FVSR EADI AGK++EHGE+E NLYGT IDS
Sbjct 362 NPTRFGTTVPFTSRKPREDEKDGQAYKFVSRSEMEADIKAGKYLEHGEYEGNLYGTKIDS 421
Query 563 VRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRAL---LAKEGKNPK-- 617
+ +V+ +G+ C+L + Q+LK LR S+ PY++FIA P E LRA+ + G K
Sbjct 422 ILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAAPELETLRAMHKAVVDAGITTKLL 481
Query 618 -PEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
+L++ ++++ +++ HYFD I+N +LDKA+++L I KL EPQWVP +W+
Sbjct 482 TDSDLKKTVDESARIQRAYNHYFDLIIINDNLDKAFEKLQTAIEKLRMEPQWVPISWV 539
>sp|O88910|MPP3_MOUSE MAGUK p55 subfamily member 3 OS=Mus musculus
OX=10090 GN=Mpp3 PE=1 SV=2
Length=568
Score = 332 bits (850), Expect = 3e-104, Method: Compositional matrix adjust.
Identities = 195/552 (35%), Positives = 325/552 (59%), Gaps = 60/552 (11%)
Query 140 DSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKP 199
DS +E++ L + K KIH + + ++ P P++ +A LA++V L+
Sbjct 24 DSNHREEMGFLRDVFSEKSLSYLMKIHEKLRYYERQS--PTPVLHSAMALAEDVMEELQA 81
Query 200 VH-HKEGQELTALLNTPHIQALLLAHDKVAEQEMQ--LEPITDERVYESIGQ-YGGETVK 255
H + +EL LL+TPH++A+L+ HD VA++ L P+ D +I + + E+VK
Sbjct 82 ASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPD-----NIDEDFEEESVK 136
Query 256 IVRIEKARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
IVR+ K ++ PLGAT+R + S V+++RI++GGAA++SGL+H GDE+ E+NGI + K
Sbjct 137 IVRLVKNKE-PLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKR 195
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSF 373
+E+ +L+ G++T +IP+ Q + K++ + ++A F YDP +D +PC+E GL F
Sbjct 196 PDEISQILAQSQGSITLKIIPATQ-EEDRFKDSKVFMRALFHYDPREDRAIPCQEAGLPF 254
Query 374 QKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPE--- 430
Q+ +L V+SQ+DP WWQA R GD + + AGL+P K FQ++R + ++T P+
Sbjct 255 QRRQVLEVVSQDDPTWWQAKRVGDTNLR--AGLIPSKQFQERRLSYRRTTGTLPSPQNFK 312
Query 431 ----------------------------KSGKLWCAKK-NKKKRKKVLYNANKNDDYDNE 461
+S +L C ++ + KV A +++
Sbjct 313 KPPYDQPCDKETCDCDGYFKGHYVAGLRRSFRLGCRERLGGSQEAKVPTGA------ESQ 366
Query 462 EILTYEEMSLY-HQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRD 520
+LTYEE++ Y HQP R R ++LIG +EL+QR++ ++ +FA AVPHTTR R+
Sbjct 367 VLLTYEEVARYQHQPGERPRLVVLIGSLGAHLHELKQRVVAEDPQQFAVAVPHTTRPRKS 426
Query 521 QEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQ 580
E G +YHFVS+QAFEAD+ KF+EHGE+++NLYGTS+++++ V+ K+CL+ + +
Sbjct 427 HERDGVEYHFVSKQAFEADVHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPE 486
Query 581 SLKTLRNSDLKPYIIFIAPPSQERLR----ALLAKEGKNPKPEELREIIEKTREMEQNNG 636
+L+ LR + KPY+IF+ P QER + + +++ + E+ +E+ ++Q+ G
Sbjct 487 ALRHLRTPEFKPYVIFVKPAIQERRKTPPVSPDSEDIASSLDEQQQEMAASAAFIDQHYG 546
Query 637 HYFDTAIVNSDL 648
H DT +V DL
Sbjct 547 HLIDTVLVRQDL 558
>sp|Q24210|CSKP_DROME Peripheral plasma membrane protein CASK
OS=Drosophila melanogaster OX=7227 GN=CASK PE=1 SV=4
Length=898
Score = 303 bits (777), Expect = 2e-90, Method: Compositional matrix adjust.
Identities = 205/652 (31%), Positives = 344/652 (53%), Gaps = 59/652 (9%)
Query 50 IRRSAQLER--IRQQQEDMRR---RREEEGKKQELDLNSSMR-LKKLAQIPPKTGIDNPM 103
IR +L+R + E+++R RR+ +G Q + ++M L P TG +
Sbjct 278 IRDRDKLQRTHLADTVEELKRYNARRKLKGAVQAIAGGTNMDPLYATDADMPITGATDEW 337
Query 104 FDTEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAF 163
D E GI + I D + +Q VD+ D +L+ + F F
Sbjct 338 ADEEAGIE--------AVQRILDCLDDIYSLQDAHVDADVLRD---MLRDNRLHQFLQLF 386
Query 164 KIHNAITVHMNKASPPFPLISNAQDLAQEVQTV-----LKPVHHKEGQELTALLNTPHIQ 218
A V N +P + +D+ +++ + L + KE EL LL PH+Q
Sbjct 387 DRIAATVVTSNGRAPAAEAVGRCRDVLEQLSSTSGGNSLGGKYAKE--ELMRLLAAPHMQ 444
Query 219 ALLLAHDKVA-----EQEMQLEP---ITDERVYESIGQYGGET-----VKIVRIEKARDI 265
ALL +HD VA E+ +++ P + E GGE V++V+ +K D
Sbjct 445 ALLHSHDVVARDVYGEEALRVTPPPMVPYLNGDELDNVEGGELQHVTRVRLVQFQKNTDE 504
Query 266 PLGATVRNEMDS-VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
P+G T++ D I++RI+ GG + LH GDE+ EING ++ + V ++ +L +
Sbjct 505 PMGITLKMTEDGRCIVARIMHGGMIHRQATLHVGDEIREINGQPVQHQSVGQLQRMLREA 564
Query 325 HGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ 384
G++TF ++PS + PPP + I V+A FDY+P DD +PC + G+SFQ GDIL +IS+
Sbjct 565 RGSVTFKIVPSYRSAPPPCE---IFVRAQFDYNPLDDELIPCAQAGISFQVGDILQIISK 621
Query 385 EDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKK 444
+D +WWQA + + AGL+P Q+ R A QT+++ K+ + + ++ +K K+
Sbjct 622 DDHHWWQARLDTVGGS---AGLIPSPELQEWRIAC-QTVDKTKQEQVNCSIF-GRKKKQC 676
Query 445 RKKVLYNANKNDDYDNEEILTYEEMSLY--HQPANRKRPIILIGPQNCGQNELRQRLMNK 502
R K Y A N +D +++TYEE+ P +++ ++L+G G+ ++ L++K
Sbjct 677 RDK--YLAKHNAIFDTLDVVTYEEVVKVPVGDPNFQRKTLVLLGAHGVGRRHIKNTLISK 734
Query 503 EKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDS 562
D++A +PHTTR + +E GR Y+FVS ADI A +++E+G E +YGT +D+
Sbjct 735 YPDKYAYPIPHTTRPAKPEEENGRSYYFVSHDEMMADIGANEYLEYGTHEDAMYGTKLDT 794
Query 563 VRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELR 622
+R++ GK+ +L + Q+LK LR ++ PY++FIA PS L+ + +G L
Sbjct 795 IRRIHTEGKMAILDVEPQALKILRTAEFTPYVVFIAAPS---LQNIADYDGS------LE 845
Query 623 EIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
+ +++ + Q GH+FD IVN+D+ + L I+++ T PQWVP +WL
Sbjct 846 RLAKESEMLRQLYGHFFDLTIVNNDISETIATLETAIDRVHTTPQWVPVSWL 897
>sp|Q9QYH1|MPP4_RAT MAGUK p55 subfamily member 4 OS=Rattus norvegicus
OX=10116 GN=Mpp4 PE=1 SV=1
Length=441
Score = 285 bits (730), Expect = 3e-88, Method: Compositional matrix adjust.
Identities = 161/436 (37%), Positives = 248/436 (57%), Gaps = 39/436 (9%)
Query 266 PLGATV-RNEMDS-VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD 323
PLGAT+ R+E+ ++++R++ GG E++GLL+ GD+++E+NG+ + G D +V +L+
Sbjct 12 PLGATIKRHEITGDILVARVIHGGLVERNGLLYAGDKLVEVNGVPVEGLDPEQVIHILAM 71
Query 324 MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVIS 383
GT+ F +IP PP + +T ++V+A DY P +DP +PC + GL F KGDIL ++
Sbjct 72 SCGTIMFKVIPVS--APPVSSQTTVYVRAMIDYWPQEDPDIPCMDAGLPFLKGDILQIVD 129
Query 384 QEDPNWWQAYREGDEDNQPLAGLVPGKSF--QQQREAMKQTIEEDKEPEKSGKLWCAKKN 441
Q D WWQA + D AGL+P ++QRE + +P C K
Sbjct 130 QSDALWWQARK--ISDIAICAGLIPSNHLLKRKQREFW---WSQPYQPHT-----CLKST 179
Query 442 KKKRKKV-----LYNANKNDDYDNEEILT---------YEEMSLYH-QPANRKRPIILIG 486
+ K + V + A + N YEE+ Y QPA++ R I+L+G
Sbjct 180 RSKEEFVGDGQQFFIAGFRQQHANMRCTCSCYSAVGAPYEEVVRYQRQPADKHRLIVLVG 239
Query 487 PQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFI 546
P G NELR++L+ F SAVPHTTRS + E+ GR+YH+VSR+ FE+ + + +
Sbjct 240 PSGVGVNELRRQLIGCNPSCFQSAVPHTTRSPKSYEMDGREYHYVSRETFESLMYGHRML 299
Query 547 EHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLR 606
E GE++ +LYGTS+++V V++ GKIC++ L Q ++ R +LKPY+IFI PPS +R
Sbjct 300 EFGEYKGHLYGTSVNAVLAVLDEGKICVMDLEPQDIQLARTRELKPYVIFIKPPSMSSMR 359
Query 607 -----ALLAKE---GKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
A + + K E+L+E+ E ++ME G +FD IVN +L A +LL
Sbjct 360 HSRRNAKIITDYFVDMKFKDEDLQEMEELAQKMESQFGQFFDHVIVNDNLQDARAQLLSA 419
Query 659 INKLDTEPQWVPSTWL 674
I K + E QWVP W+
Sbjct 420 IQKAEEELQWVPEAWV 435
>sp|O70589|CSKP_MOUSE Peripheral plasma membrane protein CASK
OS=Mus musculus OX=10090 GN=Cask PE=1 SV=2
Length=926
Score = 284 bits (726), Expect = 7e-83, Method: Compositional matrix adjust.
Identities = 173/600 (29%), Positives = 320/600 (53%), Gaps = 70/600 (12%)
Query 124 IEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKA--SPPFP 181
+ + SL+ I H L D S++D+ L + Q++ +++ I + +PP
Sbjct 347 VSQVLDSLEEI-HALTDC-SEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSD 404
Query 182 LISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVA-----EQEMQLEP 236
+ A+++ +E+ + + + +EL +L PH ALL HD VA ++ +++ P
Sbjct 405 AVQRAKEVLEEISCYPE---NNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTP 461
Query 237 ------ITDERVYESIGQYGGETV---KIVRIEKARDIPLGATVR-NEMDSVIISRIVKG 286
+ + + G E V ++V+ +K D P+G T++ NE++ I++RI+ G
Sbjct 462 PPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHG 521
Query 287 GAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK------- 339
G + G LH GDE+ EINGI + + V ++ +L +M G++TF ++PS + +
Sbjct 522 GMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERD 581
Query 340 -PPPAKETV------------------------IHVKAHFDYDPSDDPYVPCRELGLSFQ 374
P ++++ I+V+A F+YDP+ D +PC+E G+ F+
Sbjct 582 SPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFR 641
Query 375 KGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGK 434
GDI+ +IS++D NWWQ E ++ AGL+P Q+ R A +E+ K+ +++
Sbjct 642 VGDIIQIISKDDHNWWQGKLENSKNGT--AGLIPSPELQEWRVACI-AMEKTKQEQQASC 698
Query 435 LWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNE 494
W KK K+ + K L A N +D +++TYEE + PA +++ ++L+G G+
Sbjct 699 TWFGKKKKQYKDKYL--AKHNAVFDQLDLVTYEE--VVKLPAFKRKTLVLLGAHGVGRRH 754
Query 495 LRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKN 554
++ L+ K DRFA +PHTTR + E G++Y+FVS DI+ +++E+G E
Sbjct 755 IKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDA 814
Query 555 LYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGK 614
+YGT ++++R++ G I +L + Q+LK LR ++ P+++FIA P+ G
Sbjct 815 MYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPT--------ITPGL 866
Query 615 NPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
N + E L+ + +++ +++ HYFD I+N+++D+ + L + + T PQWVP +W+
Sbjct 867 N-EDESLQRLQKESDVLQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWV 925
>sp|O14936|CSKP_HUMAN Peripheral plasma membrane protein CASK
OS=Homo sapiens OX=9606 GN=CASK PE=1 SV=3
Length=926
Score = 283 bits (725), Expect = 1e-82, Method: Compositional matrix adjust.
Identities = 173/600 (29%), Positives = 320/600 (53%), Gaps = 70/600 (12%)
Query 124 IEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKA--SPPFP 181
+ + SL+ I H L D S++D+ L + Q++ +++ I + +PP
Sbjct 347 VSQVLDSLEEI-HALTDC-SEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSD 404
Query 182 LISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVA-----EQEMQLEP 236
+ A+++ +E+ + + + +EL +L PH ALL HD VA ++ +++ P
Sbjct 405 AVQRAKEVLEEISCYPE---NNDAKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTP 461
Query 237 ------ITDERVYESIGQYGGETV---KIVRIEKARDIPLGATVR-NEMDSVIISRIVKG 286
+ + + G E V ++V+ +K D P+G T++ NE++ I++RI+ G
Sbjct 462 PPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHG 521
Query 287 GAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK------- 339
G + G LH GDE+ EINGI + + V ++ +L +M G++TF ++PS + +
Sbjct 522 GMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERD 581
Query 340 -PPPAKETV------------------------IHVKAHFDYDPSDDPYVPCRELGLSFQ 374
P ++++ I+V+A F+YDP+ D +PC+E G+ F+
Sbjct 582 SPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFR 641
Query 375 KGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGK 434
GDI+ +IS++D NWWQ E ++ AGL+P Q+ R A +E+ K+ +++
Sbjct 642 VGDIIQIISKDDHNWWQGKLENSKNGT--AGLIPSPELQEWRVACI-AMEKTKQEQQASC 698
Query 435 LWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNE 494
W KK K+ + K L A N +D +++TYEE + PA +++ ++L+G G+
Sbjct 699 TWFGKKKKQYKDKYL--AKHNAVFDQLDLVTYEE--VVKLPAFKRKTLVLLGAHGVGRRH 754
Query 495 LRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKN 554
++ L+ K DRFA +PHTTR + E G++Y+FVS DI+ +++E+G E
Sbjct 755 IKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDA 814
Query 555 LYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGK 614
+YGT ++++R++ G I +L + Q+LK LR ++ P+++FIA P+ G
Sbjct 815 MYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPT--------ITPGL 866
Query 615 NPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
N + E L+ + +++ +++ HYFD I+N+++D+ + L + + T PQWVP +W+
Sbjct 867 N-EDESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWV 925
>sp|Q62915|CSKP_RAT Peripheral plasma membrane protein CASK OS=Rattus
norvegicus OX=10116 GN=Cask PE=1 SV=1
Length=909
Score = 279 bits (714), Expect = 2e-81, Method: Compositional matrix adjust.
Identities = 168/588 (29%), Positives = 318/588 (54%), Gaps = 63/588 (11%)
Query 124 IEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKA--SPPFP 181
+ + SL+ I H L D S++D+ L + Q++ +++ I + +PP
Sbjct 347 VSQVLDSLEEI-HALTDC-SEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSD 404
Query 182 LISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALL-----LAHDKVAEQEMQLEP 236
+ A+++ +E+ + + + +EL +L PH ALL +AH+ +++ +++ P
Sbjct 405 AVQRAKEVLEEISCYPE---NNDAKELKRILTQPHFMALLQTHHVVAHEVYSDEALRVTP 461
Query 237 ------ITDERVYESIGQYGGETV---KIVRIEKARDIPLGATVR-NEMDSVIISRIVKG 286
+ + + G E V ++V+ +K D P+G T++ NE++ I++RI+ G
Sbjct 462 PPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHCIVARIMHG 521
Query 287 GAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK------- 339
G + G LH GDE+ EINGI + + V ++ +L +M G++TF ++PS + +
Sbjct 522 GMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERD 581
Query 340 -PPPAKET------------VIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQED 386
P ++++ I+V+A F+YDP+ D +PC+E G+ F+ GDI+ +IS++D
Sbjct 582 SPSTSRQSPANGHSSTNNSVSIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDD 641
Query 387 PNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRK 446
NWWQ E ++ AGL+P Q+ R A +E+ K+ +++ W KK K+ +
Sbjct 642 HNWWQGKLENSKNGT--AGLIPSPELQEWRVACI-AMEKTKQEQQASCTWFGKKKKQYKD 698
Query 447 KVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDR 506
K L N +++TYEE + PA +++ ++L+G G+ ++ L+ K +R
Sbjct 699 KYLAK-------HNADLVTYEE--VVKLPAFKRKTLVLLGAHGVGRRHIKNTLITKHPER 749
Query 507 FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQV 566
FA +PHTTR + E G++Y+FVS DI+ +++E+G E +YGT ++++R++
Sbjct 750 FAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKI 809
Query 567 INSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIE 626
G I +L + Q+LK LR ++ P+++FIA P+ G N + E L+ + +
Sbjct 810 HEQGLIAILDVEPQALKVLRTAEFPPFVVFIAAPT--------ITPGLN-EDESLQRLQK 860
Query 627 KTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
++ +++ HYFD I+N+++D+ + L + + T PQWVP +W+
Sbjct 861 ESDVLQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWV 908
>sp|Q00013|EM55_HUMAN 55 kDa erythrocyte membrane protein OS=Homo
sapiens OX=9606 GN=MPP1 PE=1 SV=2
Length=466
Score = 264 bits (674), Expect = 1e-79, Method: Compositional matrix adjust.
Identities = 135/422 (32%), Positives = 239/422 (57%), Gaps = 26/422 (6%)
Query 254 VKIVRIEKARDIPLGATVR-NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
V++++ EK + P+G T++ NE S ++RI+ GG + G LH GDE+LEING +
Sbjct 69 VRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEINGTNVTNH 128
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLS 372
V+++ + + G ++ +IP+QQ + P + + ++A FDYDP D +PC+E GL
Sbjct 129 SVDQLQKAMKETKGMISLKVIPNQQSRLPALQ---MFMRAQFDYDPKKDNLIPCKEAGLK 185
Query 373 FQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKS 432
F GDI+ +I+++D NWWQ EG AGL+P Q+ R A + P
Sbjct 186 FATGDIIQIINKDDSNWWQGRVEGSSKES--AGLIPSPELQEWRVASMAQSAPSEAPS-- 241
Query 433 GKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQ 492
C+ KKK+ K Y A + +D ++++YEE + PA +++ ++LIG G+
Sbjct 242 ----CSPFGKKKKYKDKYLAKHSSIFDQLDVVSYEE--VVRLPAFKRKTLVLIGASGVGR 295
Query 493 NELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFE 552
+ ++ L+++ ++F VP+TTR R E G++YHF+S + +I+A +F+E G ++
Sbjct 296 SHIKNALLSQNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQ 355
Query 553 KNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKE 612
N++GT ++V Q+ KI +L + Q+LK +R ++L P+I+FIAP Q
Sbjct 356 GNMFGTKFETVHQIHKQNKIAILDIEPQTLKIVRTAELSPFIVFIAPTDQ---------- 405
Query 613 GKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPST 672
+ E L+++ + + + HYFD ++VN+ +D+ ++L ++ + PQWVP +
Sbjct 406 --GTQTEALQQLQKDSEAIRSQYAHYFDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVS 463
Query 673 WL 674
W+
Sbjct 464 WV 465
>sp|A9CB74|EM55_PAPAN 55 kDa erythrocyte membrane protein OS=Papio
anubis OX=9555 GN=MPP1 PE=3 SV=1
Length=466
Score = 263 bits (672), Expect = 3e-79, Method: Compositional matrix adjust.
Identities = 135/422 (32%), Positives = 239/422 (57%), Gaps = 26/422 (6%)
Query 254 VKIVRIEKARDIPLGATVR-NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
V++++IEK + P+G T++ NE S ++RI+ GG + G LH GDE+LEING +
Sbjct 69 VRLIQIEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEINGTNVTNH 128
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLS 372
V+++ + + G ++ +IP+QQ + P + + ++A FDYDP D +PC+E GL
Sbjct 129 SVDQLQKAMKETKGMISLKVIPNQQSRLPALQ---MFMRAQFDYDPKKDNLIPCKEAGLK 185
Query 373 FQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKS 432
F GDI+ +I+++D NWWQ EG AGL+P Q+ R A + P
Sbjct 186 FATGDIIQIINKDDSNWWQGRVEGSSKES--AGLIPSPELQEWRVASIAQSAPSEAPS-- 241
Query 433 GKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQ 492
C+ KKK+ K Y A + +D ++++YEE + PA +++ ++LIG G+
Sbjct 242 ----CSPFGKKKKYKDKYLAKHSSIFDQLDVVSYEE--VVRLPAFKRKTLVLIGASGVGR 295
Query 493 NELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFE 552
+ ++ L+++ ++F P+TTR R E G++YHF+S + +I+A +F+E G ++
Sbjct 296 SHIKNALLSQNPEKFVYPAPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQ 355
Query 553 KNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKE 612
N++GT ++V Q+ KI +L + Q+LK +R ++L P+I+FIAP Q
Sbjct 356 GNMFGTKFETVHQIHKQDKIAILDIEPQTLKIVRTAELSPFIVFIAPTDQ---------- 405
Query 613 GKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPST 672
+ E L+++ + + + HYFD ++VN+ +D+ ++L ++ + PQWVP +
Sbjct 406 --GTQTEALQQLQKDSEAIRSQYAHYFDLSLVNNSVDETLKKLQEAFDQACSSPQWVPVS 463
Query 673 WL 674
W+
Sbjct 464 WV 465
>sp|Q5RDW4|EM55_PONAB 55 kDa erythrocyte membrane protein OS=Pongo
abelii OX=9601 GN=MPP1 PE=2 SV=1
Length=466
Score = 263 bits (672), Expect = 3e-79, Method: Compositional matrix adjust.
Identities = 135/422 (32%), Positives = 239/422 (57%), Gaps = 26/422 (6%)
Query 254 VKIVRIEKARDIPLGATVR-NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
V++++ EK + P+G T++ NE S ++RI+ GG + G LH GDE+LEING +
Sbjct 69 VRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEINGTNVTNH 128
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLS 372
V+++ + + G ++ +IP+QQ + P + + ++A FDYDP D +PC+E GL
Sbjct 129 SVDQLQKAMKETKGMISLKVIPNQQSRLPALQ---MFMRAQFDYDPKKDNLIPCKEAGLK 185
Query 373 FQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKS 432
F GDI+ +I+++D NWWQ EG AGL+P Q+ R A + P
Sbjct 186 FATGDIIQIINKDDSNWWQGRVEGSSKES--AGLIPSPELQEWRVASVAQSAPSEAPS-- 241
Query 433 GKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQ 492
C+ KKK+ K Y A + +D ++++YEE + PA +++ ++LIG G+
Sbjct 242 ----CSPFGKKKKYKDKYLAKHSSIFDQLDVVSYEE--VVRLPAFKRKTLVLIGASGVGR 295
Query 493 NELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFE 552
+ ++ L+++ ++F VP+TTR R E G++YHF+S + +I+A +F+E G ++
Sbjct 296 SHIKNALLSQNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEFLEFGSYQ 355
Query 553 KNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKE 612
N++GT ++V Q+ KI +L + Q+LK +R ++L P+I+FIAP Q
Sbjct 356 GNMFGTKFETVHQIHKQDKIAILDIEPQTLKIVRTAELSPFIVFIAPTDQ---------- 405
Query 613 GKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPST 672
+ E L+++ + + + HYFD ++VN+ +D+ ++L ++ + PQWVP +
Sbjct 406 --GTQTEALQQLQKDSEAIRSQYAHYFDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVS 463
Query 673 WL 674
W+
Sbjct 464 WV 465
>sp|P70290|EM55_MOUSE 55 kDa erythrocyte membrane protein OS=Mus
musculus OX=10090 GN=Mpp1 PE=1 SV=1
Length=466
Score = 262 bits (669), Expect = 7e-79, Method: Compositional matrix adjust.
Identities = 134/422 (32%), Positives = 238/422 (56%), Gaps = 26/422 (6%)
Query 254 VKIVRIEKARDIPLGATVR-NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
V++++ EK + P+G T++ NE S ++RI+ GG + G LH GDE+LEING +
Sbjct 69 VRLIQFEKITEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEINGTNVTNH 128
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLS 372
V+++ + + G ++ +I +QQ + P + + ++A FDYDP D +PC+E GL
Sbjct 129 SVDQLQKAMKETKGMISLKVIANQQSRLPALQ---MFMRAQFDYDPQKDNLIPCKEAGLK 185
Query 373 FQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKS 432
F GDI+ +I+++D NWWQ EG AGL+P Q+ R A + P
Sbjct 186 FVTGDIIQIINKDDSNWWQGRVEGSSKES--AGLIPSPELQEWRVASVAHSAPSEAPS-- 241
Query 433 GKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQ 492
C+ KKK+ K Y A + +D ++++YEE + PA +++ ++LIG G+
Sbjct 242 ----CSPFGKKKKCKDKYLAKHSSIFDQLDVVSYEE--VVRLPAFKRKTLVLIGASGVGR 295
Query 493 NELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFE 552
+ ++ L++ ++FA P+TTR + E G++YHF+S + +I+A +F+E G ++
Sbjct 296 SHIKNGLLSHNPEKFAYPAPYTTRPPKKSEEDGKEYHFISTEEMTKNISANEFLEFGSYQ 355
Query 553 KNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKE 612
N++GT ++V Q+ KI +L + Q+LKT+R ++L P+I+FIAP Q
Sbjct 356 GNMFGTKFETVHQIHKQDKIAILDIEPQTLKTVRTAELSPFIVFIAPTDQ---------- 405
Query 613 GKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPST 672
+ E L+++ + + + HYFD ++VN+ +D+ ++L ++ + PQWVP +
Sbjct 406 --GTQTEALQQLQKDSEAIRSQYAHYFDLSLVNNSVDETLKKLQEAFDQACSSPQWVPVS 463
Query 673 WL 674
W+
Sbjct 464 WV 465
>sp|Q17QN6|EM55_BOVIN 55 kDa erythrocyte membrane protein OS=Bos
taurus OX=9913 GN=MPP1 PE=1 SV=1
Length=466
Score = 259 bits (662), Expect = 6e-78, Method: Compositional matrix adjust.
Identities = 143/489 (29%), Positives = 259/489 (53%), Gaps = 35/489 (7%)
Query 196 VLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYG----- 250
LK + G + L+ +++ LL H++ QL + ++ G
Sbjct 2 TLKASEGEGGGGMRTALSDLYLEHLLQKHNRPEPVSPQLSAVMEDMYTNGPAALGSPAQT 61
Query 251 ----GETVKIVRIEKARDIPLGATVR-NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
V++++ EK + P+G T++ NE S ++RI+ GG + G LH GDE+LEIN
Sbjct 62 QGQEARKVRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMVHRQGSLHVGDEILEIN 121
Query 306 GIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVP 365
G + V+++ + + G ++ +IP+QQ + P + + ++A FDYDP D +P
Sbjct 122 GTNVTNHSVDQLQKAMKETKGMISLKVIPNQQNRLPALQ---MFMRAQFDYDPRKDNLIP 178
Query 366 CRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEE 425
C+E GL F GD++ +I+++D NWWQ EG +Q AGL+P Q+ R A
Sbjct 179 CKEAGLKFLTGDVIQIINKDDSNWWQGRVEGS--SQESAGLIPSPELQEWRVASGAHSAP 236
Query 426 DKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILI 485
+ P C+ KKK+ K Y A + +D ++++YEE + PA +++ ++LI
Sbjct 237 SEAPS------CSPFGKKKKYKDKYLAKHSAIFDQLDVVSYEE--VVRLPAFKRKTLVLI 288
Query 486 GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKF 545
G G++ ++ L+++ D+FA P+TTR R E G++YHF+S + I+A +F
Sbjct 289 GASGVGRSHIKSALLSQNPDKFAYPAPYTTRPARKSEEDGKEYHFISTEEMTRSISANEF 348
Query 546 IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERL 605
+E G ++ N++GT ++V Q+ K+ +L + Q+LK +R ++L P+I+FIAP Q
Sbjct 349 LEFGSYQGNMFGTKFETVHQIHKQDKVAILDIEPQTLKIVRTAELSPFIVFIAPTDQ--- 405
Query 606 RALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTE 665
+ + L+++ + + + HYFD ++VN+ +++ + L ++
Sbjct 406 ---------GTQTDTLQQLQKDSEAIRSQYAHYFDLSLVNNSVEETLKTLQETFDQACRS 456
Query 666 PQWVPSTWL 674
PQWVP +W+
Sbjct 457 PQWVPVSWV 465
>sp|P54936|LIN2_CAEEL Protein lin-2 OS=Caenorhabditis elegans
OX=6239 GN=lin-2 PE=1 SV=1
Length=961
Score = 271 bits (692), Expect = 7e-78, Method: Compositional matrix adjust.
Identities = 150/434 (35%), Positives = 246/434 (57%), Gaps = 30/434 (7%)
Query 254 VKIVRIEKARDIPLGATVR-NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
+++V+ +K P+G T++ NE ++RI+ GG + LH GDE+ EING+ + +
Sbjct 544 LRLVQFQKDTQEPMGITLKVNEDGRCFVARIMHGGMIHRQATLHVGDEIREINGMSVANR 603
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLS 372
V + ++L D G +TF +IPS + PP + I V+A FDY+PS D +PC + G+
Sbjct 604 SVESLQEMLRDARGQVTFKIIPSYRSAPPACE---IFVRAQFDYEPSQDDLIPCPQAGIP 660
Query 373 FQKGDILHVISQEDPNWWQAY------REGDEDN------QPLAGLVPGKSFQQQREAMK 420
F+ GDIL VIS++D NWWQA G+ N Q +AGL+P Q+ R A
Sbjct 661 FKTGDILQVISKDDHNWWQARFVSSFPSIGNSSNAQRSNQQQVAGLIPSPELQEWRTAC- 719
Query 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
+E K + +W KK K K L + +D +++TYEE+ Q R++
Sbjct 720 LAMERSKNTCNTHCMWFNKKKKYYTTKYL--QKHSALFDQLDLVTYEEVMRLSQ--YRRK 775
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
++L+G G+ ++ L+++ +RFA +PHTTR R EV G+ Y+FV+ + ADI
Sbjct 776 TLVLLGAHGVGRRHIKNTLIHRHPNRFAYPIPHTTRPPRKDEVDGKHYYFVTNEQMMADI 835
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
+++E+G E+++YGT ++++R + SGKI +L + Q+LK LR ++ P+++FIA P
Sbjct 836 QNNEYLEYGTHEESMYGTKLETIRNIHKSGKIAILDVEPQALKVLRTAEYSPFVVFIAAP 895
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
+ L+ + +G L +++ ++ + Q GH FD I NSD+D +L RL+
Sbjct 896 N---LQGMQDPDGS------LEKLLNESDVLRQAFGHLFDFIITNSDIDDTIAQLERLVE 946
Query 661 KLDTEPQWVPSTWL 674
KL PQW+P TW+
Sbjct 947 KLPAYPQWLPVTWV 960
>sp|Q5ZJ00|EM55_CHICK 55 kDa erythrocyte membrane protein OS=Gallus
gallus OX=9031 GN=MPP1 PE=2 SV=1
Length=468
Score = 259 bits (661), Expect = 1e-77, Method: Compositional matrix adjust.
Identities = 133/422 (32%), Positives = 243/422 (58%), Gaps = 26/422 (6%)
Query 254 VKIVRIEKARDIPLGATVR-NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
+++V+ EK + P+G T++ N+ S +++RI GG + G LH GDE++EING +
Sbjct 71 IRLVQFEKVTEEPMGITLKLNDKQSCMVARIFHGGMIHRQGSLHVGDEIIEINGQSVSNH 130
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLS 372
V+++ +L + G ++ +IP+QQ + P + + ++A FDYDP D +PC+E GL
Sbjct 131 SVDQLQKMLKETQGMVSIKVIPNQQSRLPALQ---MFMRAQFDYDPKKDNLIPCKEAGLK 187
Query 373 FQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKS 432
FQ GD++ +I+++D NWWQ EG AGL+P Q+ R A ++ + + E
Sbjct 188 FQTGDVIQIINKDDSNWWQGRVEGSGTES--AGLIPSPELQEWRVA---SVTQSSQSEAQ 242
Query 433 GKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQ 492
C+ KKK+ K Y A + +D ++++YEE + PA +++ ++LIG G+
Sbjct 243 S---CSPFGKKKKYKDKYLAKHSSIFDQLDVVSYEE--VVRLPAFKRKTLVLIGASGVGR 297
Query 493 NELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFE 552
+ ++ L++ ++F P+TTR ++ EV G+DY+FVS + DI+A +F+E G ++
Sbjct 298 SHIKNALLSNNPEKFMYPPPYTTRPQKKNEVDGKDYYFVSTEEMTRDISANEFLEFGSYQ 357
Query 553 KNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKE 612
N++GT ++V ++ K+ +L + Q+LK +R ++L P+I+FIAP
Sbjct 358 GNMFGTKFETVHKIHQQDKVAILDIEPQTLKIVRTAELSPFIVFIAPTD----------- 406
Query 613 GKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPST 672
K + E L+++ + + + HYFD +IVN+ ++++ + L + + PQWVP +
Sbjct 407 -KAEESEALQQLRKDSESIRSRYAHYFDLSIVNNGVEESLKLLEEAFEQACSSPQWVPVS 465
Query 673 WL 674
W+
Sbjct 466 WV 467
>sp|P49697|EM55_TAKRU 55 kDa erythrocyte membrane protein OS=Takifugu
rubripes OX=31033 GN=mpp1 PE=3 SV=1
Length=467
Score = 255 bits (651), Expect = 3e-76, Method: Compositional matrix adjust.
Identities = 135/419 (32%), Positives = 233/419 (56%), Gaps = 27/419 (6%)
Query 257 VRIEKARDIPLGATVR-NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVN 315
V EK + PLG T++ N+ ++RI+ GG + G LHEGDE+ EING + + V+
Sbjct 74 VAFEKNQSEPLGVTLKLNDKQRCSVARILHGGMIHRQGSLHEGDEIAEINGKSVANQTVD 133
Query 316 EVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQK 375
++ +L + +G +T +IP Q + P + ++++ FDYDP+ D +PC+E GL FQ
Sbjct 134 QLQKILKETNGVVTMKIIPRPQSRSKPCE---MYMRGQFDYDPAMDDLIPCKEAGLKFQT 190
Query 376 GDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKL 435
GDI+ +I+++DPNWWQ E + N AGL+P Q+ R A K E G
Sbjct 191 GDIIQIINKQDPNWWQGRVENNAAN--FAGLIPSPELQEWRAASKSKARE-------GSQ 241
Query 436 WCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNEL 495
C+ KKK+ K Y A + +D ++++YEE + PA +++ ++LIG G+ +
Sbjct 242 SCSPFGKKKKCKDKYLAKHSSIFDQLDVISYEE--VVRLPAFKRKTLVLIGAPGVGRRHI 299
Query 496 RQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNL 555
+ L+ K ++F+ VPHTTR +R + G +Y F+S +A I+A + +E+G F+ +
Sbjct 300 KNVLLTKYPEKFSYPVPHTTRPQRKGDANGEEYFFISNEAMTKCISANELLEYGSFQGYM 359
Query 556 YGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKN 615
+GT ++++++ KI LL + Q++K LR +D P ++FIAP
Sbjct 360 FGTITETIQKIHEQDKIALLDVEPQTMKVLRTADFGPLMVFIAPTDTA------------ 407
Query 616 PKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
+ E L+ I +++ + YFD +VN+D++++ + + + T PQWVP +W+
Sbjct 408 AQTENLQMIQKESETILNTYRQYFDVVLVNNDVNESVKIVEEALEHATTTPQWVPVSWV 466
>sp|Q15700|DLG2_HUMAN Disks large homolog 2 OS=Homo sapiens OX=9606
GN=DLG2 PE=1 SV=3
Length=870
Score = 212 bits (539), Expect = 3e-57, Method: Compositional matrix adjust.
Identities = 156/467 (33%), Positives = 231/467 (49%), Gaps = 63/467 (13%)
Query 251 GETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
GE K+V + + + + + + +S I+ GG A+ SG L GD++L +NGI++R
Sbjct 417 GEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLR 476
Query 311 GKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIH--------------------- 349
G + L T+T +I Q + E IH
Sbjct 477 GASHEQAAAALKGAGQTVT--IIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTN 534
Query 350 ------VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPL 403
V+A FDYD S D +P + GLSF+ GDILHVI+ D WWQA R E +
Sbjct 535 QKRSLYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRVMLEGDSEE 592
Query 404 AGLVPGKSFQQQRE-AMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEE 462
G++P K +++E A +T++ + +P G + KRKK + K Y N+E
Sbjct 593 MGVIPSKRRVERKERARLKTVKFNAKP---GVIDSKGSFNDKRKKSFIFSRKFPFYKNKE 649
Query 463 ----------------ILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDR 506
IL+YE ++ Q N RP+I++GP ++ + L+++ D+
Sbjct 650 QSEQETSDPERGQEDLILSYEPVT--RQEINYTRPVIILGPM---KDRINDDLISEFPDK 704
Query 507 FASAVPHTTRSRRDQEVAGRDYHFV-SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQ 565
F S VPHTTR +RD EV GRDYHFV SR+ E DI KFIE G++ NLYGTS+ SVR
Sbjct 705 FGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRF 764
Query 566 VINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREII 625
V GK C+L + ++K L+ + L P IFI P S E L + K E+ ++
Sbjct 765 VAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEM----NKRLTEEQAKKTY 820
Query 626 EKTREMEQNNGHYFDTAIVNSD-LDKAYQELLRLINKLDTEPQWVPS 671
++ ++EQ G YF TAIV D L+ Y + +I + W+PS
Sbjct 821 DRAIKLEQEFGEYF-TAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPS 866
Score = 35.0 bits (79), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Query 254 VKIVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
+K+ + K + V N+ +S+ +++I+ GGAA+K G L GD +L +N
Sbjct 194 IKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVN 249
>sp|Q91XM9|DLG2_MOUSE Disks large homolog 2 OS=Mus musculus OX=10090
GN=Dlg2 PE=1 SV=2
Length=852
Score = 203 bits (516), Expect = 2e-54, Method: Compositional matrix adjust.
Identities = 148/456 (32%), Positives = 227/456 (50%), Gaps = 59/456 (13%)
Query 251 GETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
GE K+V + + + + + + +S I+ GG A+ SG L GD++L +NGI++R
Sbjct 417 GEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLR 476
Query 311 GKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIH--------------------- 349
G + L T+T +I Q + E IH
Sbjct 477 GASHEQAAAALKGAGQTVT--IIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTN 534
Query 350 ------VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPL 403
V+A FDYD S D +P + GLSF+ GDILHVI+ D WWQA R + +
Sbjct 535 QKRSLYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRVTLDGDSEE 592
Query 404 AGLVPGKSFQQQRE-AMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEE 462
G++P K +++E A +T++ + +P + K L +D Y +
Sbjct 593 MGVIPSKRRVERKERARLKTVKFNAKP--------GVIDSKGDIPGL----GDDGYGTKT 640
Query 463 ILTYEEMSLYHQPANRK-----RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRS 517
+ E++ L ++P R+ RP+I++GP ++ + L+++ D+F S VPHTTR
Sbjct 641 LRGQEDLILSYEPVTRQEINYTRPVIILGPM---KDRINDDLISEFPDKFGSCVPHTTRP 697
Query 518 RRDQEVAGRDYHFV-SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLS 576
+RD EV GRDYHFV SR+ E DI KFIE G++ NLYGTS+ SVR V GK C+L
Sbjct 698 KRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHCILD 757
Query 577 LRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNG 636
+ ++K L+ + L P IFI P S E L + K E+ ++ ++ ++EQ G
Sbjct 758 VSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEM----NKRLTEEQAKKTYDRAIKLEQEFG 813
Query 637 HYFDTAIVNSD-LDKAYQELLRLINKLDTEPQWVPS 671
YF TAIV D L+ Y + +I + W+PS
Sbjct 814 EYF-TAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPS 848
Score = 35.0 bits (79), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Query 254 VKIVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
+K+ + K + V N+ +S+ +++I+ GGAA+K G L GD +L +N
Sbjct 194 IKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVN 249
>sp|Q63622|DLG2_RAT Disks large homolog 2 OS=Rattus norvegicus
OX=10116 GN=Dlg2 PE=1 SV=1
Length=852
Score = 202 bits (515), Expect = 3e-54, Method: Compositional matrix adjust.
Identities = 150/459 (33%), Positives = 229/459 (50%), Gaps = 65/459 (14%)
Query 251 GETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
GE K+V + + + + + + +S I+ GG A+ SG L GD++L +NGI++R
Sbjct 417 GEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLR 476
Query 311 GKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIH--------------------- 349
G + L T+T +I Q + E IH
Sbjct 477 GASHEQAAAALKGAGQTVT--IIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTN 534
Query 350 ------VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR---EGDEDN 400
V+A FDYD S D +P + GLSF+ GDILHVI+ D WWQA R +GD +
Sbjct 535 QKRSLYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRVILDGDSEE 592
Query 401 QPLAGLVPGKSFQQQRE-AMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYD 459
G++P K +++E A +T++ + +P + K L +D Y
Sbjct 593 M---GVIPSKRRVERKERARLKTVKFNAKP--------GVIDSKGDIPGL----GDDGYG 637
Query 460 NEEILTYEEMSLYHQPANRK-----RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHT 514
+ + E++ L ++P R+ RP+I++GP ++ + L+++ D+F S VPHT
Sbjct 638 TKTLRGQEDLILSYEPVTRQEINYTRPVIILGPM---KDRINDDLISEFPDKFGSCVPHT 694
Query 515 TRSRRDQEVAGRDYHFV-SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKIC 573
TR +RD EV GRDYHFV SR+ E DI KFIE G++ NLYGTS+ SVR V GK C
Sbjct 695 TRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVAERGKHC 754
Query 574 LLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQ 633
+L + ++K L+ + L P IFI P S E L + K E+ ++ ++ ++EQ
Sbjct 755 ILDVSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEM----NKRLTEEQAKKTYDRAIKLEQ 810
Query 634 NNGHYFDTAIVNSD-LDKAYQELLRLINKLDTEPQWVPS 671
G YF TAIV D L+ Y + +I + W+PS
Sbjct 811 EFGEYF-TAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPS 848
Score = 35.0 bits (79), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Query 254 VKIVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
+K+ + K + V N+ +S+ +++I+ GGAA+K G L GD +L +N
Sbjct 194 IKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVN 249
>sp|Q12959|DLG1_HUMAN Disks large homolog 1 OS=Homo sapiens OX=9606
GN=DLG1 PE=1 SV=2
Length=904
Score = 197 bits (502), Expect = 3e-52, Method: Compositional matrix adjust.
Identities = 137/431 (32%), Positives = 224/431 (52%), Gaps = 52/431 (12%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ + IS I+ GG A+ SG L +GD ++ +N +++R + L + +T V
Sbjct 487 EGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIV---- 542
Query 336 QQIKPP-----------------------------PAKETVIHVKAHFDYDPSDDPYVPC 366
Q +P +++ ++V+A FDYD + D +P
Sbjct 543 AQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPS 602
Query 367 RELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQRE-AMKQTIEE 425
+ GL+F+ GDILHVI+ D WWQA + + G++P K +++E A +T++
Sbjct 603 Q--GLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKF 660
Query 426 DKEPEKSGKLWCAKKNKKKRKKVLYNANKNDD-YDNEE--ILTYEEMSLYHQPANRKRPI 482
+ + G++ K K V NA+ ++ Y +E +L+YE ++ Q N RP+
Sbjct 661 NSKTRDKGEI-PDDMGSKGLKHVTSNASDSESSYRGQEEYVLSYEPVN--QQEVNYTRPV 717
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFV-SRQAFEADIA 541
I++GP ++ + L+++ D+F S VPHTTR +RD EV GRDYHFV SR+ E DI
Sbjct 718 IILGPM---KDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQ 774
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
KFIE G++ +LYGTS+ SVR+V GK C+L + ++K L+ + L P IFI P S
Sbjct 775 EHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKS 834
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD-LDKAYQELLRLIN 660
E + + K E+ R+ E+ ++EQ +F TAIV D L+ Y ++ ++I
Sbjct 835 MENIMEM----NKRLTEEQARKTFERAMKLEQEFTEHF-TAIVQGDTLEDIYNQVKQIIE 889
Query 661 KLDTEPQWVPS 671
+ WVP+
Sbjct 890 EQSGSYIWVPA 900
Score = 37.0 bits (84), Expect = 0.74, Method: Compositional matrix adjust.
Identities = 17/58 (29%), Positives = 34/58 (59%), Gaps = 4/58 (7%)
Query 254 VKIVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
+K+++ K + V N+ +S+ +++I++GGAA K G L GD++L +N +
Sbjct 320 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNV 377
>sp|Q62936|DLG3_RAT Disks large homolog 3 OS=Rattus norvegicus
OX=10116 GN=Dlg3 PE=1 SV=1
Length=849
Score = 196 bits (497), Expect = 7e-52, Method: Compositional matrix adjust.
Identities = 140/437 (32%), Positives = 213/437 (49%), Gaps = 57/437 (13%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ + +S I+ GG A+ SG L GD +L +NG+ +R + L ++T V
Sbjct 425 EGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIV---- 480
Query 336 QQIKPP-----------------------------PAKETVIHVKAHFDYDPSDDPYVPC 366
Q +P +++ ++V+A FDYD + D +P
Sbjct 481 AQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPS 540
Query 367 RELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQRE--------- 417
+ GLSF GDILHVI+ D WWQA G++P K +++E
Sbjct 541 Q--GLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKF 598
Query 418 -AMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPA 476
A IE +++ + KN K ++ + + IL+YE ++ Q
Sbjct 599 HARTGMIESNRDFPGLSDDYYGAKNLKGVTSNTSDSESSSKGQEDAILSYEPVT--RQEI 656
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFV-SRQA 535
+ RP+I++GP ++ + L+++ +F S VPHTTR RRD EV G+DYHFV SR+
Sbjct 657 HYARPVIILGPM---KDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQ 713
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
E DI KFIE G+F NLYGTSI SVR V GK C+L + ++K L+ + L P I
Sbjct 714 MEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAI 773
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD-LDKAYQE 654
FI P S E L + ++ E+ +I +K ++EQ G YF TAIV D L++ Y +
Sbjct 774 FIKPKSIEALMEMNRRQTY----EQANKIFDKAMKLEQEFGEYF-TAIVQGDSLEEIYNK 828
Query 655 LLRLINKLDTEPQWVPS 671
+ ++I WVPS
Sbjct 829 IKQIIEDQSGHYIWVPS 845
Score = 35.0 bits (79), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 14/35 (40%), Positives = 25/35 (71%), Gaps = 0/35 (0%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
+S+ I++I++GGAA+K G L GD +L +N ++
Sbjct 271 NSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQ 305
>sp|P70175|DLG3_MOUSE Disks large homolog 3 OS=Mus musculus OX=10090
GN=Dlg3 PE=1 SV=1
Length=849
Score = 196 bits (497), Expect = 7e-52, Method: Compositional matrix adjust.
Identities = 140/437 (32%), Positives = 213/437 (49%), Gaps = 57/437 (13%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ + +S I+ GG A+ SG L GD +L +NG+ +R + L ++T V
Sbjct 425 EGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIV---- 480
Query 336 QQIKPP-----------------------------PAKETVIHVKAHFDYDPSDDPYVPC 366
Q +P +++ ++V+A FDYD + D +P
Sbjct 481 AQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPS 540
Query 367 RELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQRE--------- 417
+ GLSF GDILHVI+ D WWQA G++P K +++E
Sbjct 541 Q--GLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKF 598
Query 418 -AMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPA 476
A IE +++ + KN K ++ + + IL+YE ++ Q
Sbjct 599 HARTGMIESNRDFPGLSDDYYGAKNLKGVTSNTSDSESSSKGQEDAILSYEPVT--RQEI 656
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFV-SRQA 535
+ RP+I++GP ++ + L+++ +F S VPHTTR RRD EV G+DYHFV SR+
Sbjct 657 HYARPVIILGPM---KDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQ 713
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
E DI KFIE G+F NLYGTSI SVR V GK C+L + ++K L+ + L P I
Sbjct 714 MEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAI 773
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD-LDKAYQE 654
FI P S E L + ++ E+ +I +K ++EQ G YF TAIV D L++ Y +
Sbjct 774 FIKPKSIEALMEMNRRQTY----EQANKIFDKAMKLEQEFGEYF-TAIVQGDSLEEIYNK 828
Query 655 LLRLINKLDTEPQWVPS 671
+ ++I WVPS
Sbjct 829 IKQIIEDQSGHYIWVPS 845
Score = 35.0 bits (79), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 14/30 (47%), Positives = 23/30 (77%), Gaps = 0/30 (0%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
+S+ I++I++GGAA+K G L GD +L +N
Sbjct 271 NSIYITKIIEGGAAQKDGRLQIGDRLLAVN 300
>sp|Q92796|DLG3_HUMAN Disks large homolog 3 OS=Homo sapiens OX=9606
GN=DLG3 PE=1 SV=2
Length=817
Score = 194 bits (494), Expect = 2e-51, Method: Compositional matrix adjust.
Identities = 139/427 (33%), Positives = 212/427 (50%), Gaps = 51/427 (12%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ + +S I+ GG A+ SG L GD +L +NG+ +R + L ++T V
Sbjct 407 EGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIV---- 462
Query 336 QQIKPP-----------------------------PAKETVIHVKAHFDYDPSDDPYVPC 366
Q +P +++ ++V+A FDYD + D +P
Sbjct 463 AQYRPEEYSRFESKIHDLREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPS 522
Query 367 RELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEED 426
+ GLSF GDILHVI+ D WWQA G++P K +++E + ++
Sbjct 523 Q--GLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKE--RARLKTV 578
Query 427 KEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIG 486
K ++G + + Y KN + IL+YE ++ Q + RP+I++G
Sbjct 579 KFHARTGMIESNRDFPGLSDD--YYGAKNLKGQEDAILSYEPVT--RQEIHYARPVIILG 634
Query 487 PQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFV-SRQAFEADIAAGKF 545
P ++ + L+++ +F S VPHTTR RRD EV G+DYHFV SR+ E DI KF
Sbjct 635 PM---KDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKF 691
Query 546 IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERL 605
IE G+F NLYGTSI SVR V GK C+L + ++K L+ + L P IFI P S E L
Sbjct 692 IEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEAL 751
Query 606 RALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD-LDKAYQELLRLINKLDT 664
+ ++ E+ +I +K ++EQ G YF TAIV D L++ Y ++ ++I
Sbjct 752 MEMNRRQTY----EQANKIYDKAMKLEQEFGEYF-TAIVQGDSLEEIYNKIKQIIEDQSG 806
Query 665 EPQWVPS 671
WVPS
Sbjct 807 HYIWVPS 813
Score = 35.0 bits (79), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
Query 254 VKIVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
V +++ K + + N+ +S+ I++I++GGAA+K G L GD +L +N
Sbjct 227 VNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVN 282
>sp|Q811D0|DLG1_MOUSE Disks large homolog 1 OS=Mus musculus OX=10090
GN=Dlg1 PE=1 SV=1
Length=905
Score = 194 bits (492), Expect = 6e-51, Method: Compositional matrix adjust.
Identities = 136/431 (32%), Positives = 220/431 (51%), Gaps = 51/431 (12%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ + IS I+ GG A+ SG L +GD ++ +N +++R + L + +T V
Sbjct 487 EGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIV---- 542
Query 336 QQIKPP-----------------------------PAKETVIHVKAHFDYDPSDDPYVPC 366
Q +P +++ ++V+A FDYD + D +P
Sbjct 543 AQYRPEEYSRFEAKIHDLREQMMNSSVSSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPS 602
Query 367 RELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQRE-AMKQTIEE 425
+ GL+F+ GDILHVI+ D WWQA + + G++P K +++E A +T++
Sbjct 603 Q--GLNFRFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKF 660
Query 426 DKEPEKSGKLWCAKKNKKKRKKVLYNANKNDD-YDNEE--ILTYEEMSLYHQPANRKRPI 482
+ + K K V NA+ ++ Y +E +L+YE ++ Q N RP+
Sbjct 661 NSKTRGDKGEIPDDMGSKGLKHVTSNASDSESSYRGQEEYVLSYEPVN--QQEVNYTRPV 718
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFV-SRQAFEADIA 541
I++GP ++ + L+++ D+F S VPHTTR +RD EV GRDYHFV SR+ E DI
Sbjct 719 IILGPM---KDRVNDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQ 775
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
KFIE G++ +LYGTS+ SVR V GK C+L + ++K L+ + L P IFI P S
Sbjct 776 EHKFIEAGQYNNHLYGTSVQSVRAVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKS 835
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD-LDKAYQELLRLIN 660
E + + K E+ R+ E+ ++EQ +F TAIV D L+ Y ++ ++I
Sbjct 836 MENIMEM----NKRLTEEQARKTFERAMKLEQEFTEHF-TAIVQGDTLEDIYNQVKQIIE 890
Query 661 KLDTEPQWVPS 671
+ WVP+
Sbjct 891 EQSGPYIWVPA 901
Score = 37.0 bits (84), Expect = 0.67, Method: Compositional matrix adjust.
Identities = 17/58 (29%), Positives = 34/58 (59%), Gaps = 4/58 (7%)
Query 254 VKIVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
+K+++ K + V N+ +S+ +++I++GGAA K G L GD++L +N +
Sbjct 320 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSV 377
>sp|Q5PYH7|DLG2_DANRE Disks large homolog 2 OS=Danio rerio OX=7955
GN=dlg2 PE=2 SV=1
Length=881
Score = 193 bits (490), Expect = 9e-51, Method: Compositional matrix adjust.
Identities = 142/448 (32%), Positives = 226/448 (50%), Gaps = 67/448 (15%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL--- 332
+ + +S I+ GG A+ SG L GD++L +NGI++RG + L T+T +
Sbjct 445 EGIFVSFILAGGPADLSGELRRGDQILSVNGIDLRGATHEQAAAALKGAGQTVTIIAQYR 504
Query 333 ----------------------IPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELG 370
+ S ++ ++V+A FDY+ + D +P + G
Sbjct 505 PEEYGRFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRALFDYERAKDSGLPSQ--G 562
Query 371 LSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQRE-AMKQTIEEDKEP 429
LSF+ GDILHVI+ D WWQA R E + G++P K +++E A +T++ + +P
Sbjct 563 LSFRYGDILHVINASDDEWWQARRVTPEGDSEEMGVIPSKRRVERKERARLKTVKFNAKP 622
Query 430 EKSGKLWC-AKKNKKKRKKVLY----------NANKNDDYDNEE-----ILTYEEMSLYH 473
G L ++K+RK ++ +A++ D D+E IL+YE +
Sbjct 623 ---GSLDSKGSFSEKRRKNFIFSRKFPFYKNKDADEQDGSDSERSQEELILSYE--PVIR 677
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVP--------HTTRSRRDQEVAG 525
Q N RP+I++GP ++ + L+++ D+F S VP TTR +RD EV G
Sbjct 678 QEINYARPVIILGPM---KDRINDDLISEFPDKFGSCVPPANSSDQEDTTRPKRDYEVDG 734
Query 526 RDYHFV-SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKT 584
RDYHF+ SR+ E DI KFIE G++ NLYGTS+ SV+ V GK C+L + ++K
Sbjct 735 RDYHFMASREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVKYVAERGKHCILDVSGNAIKR 794
Query 585 LRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIV 644
L+ + L P IFI P S E L + K E+ ++ ++ ++EQ G YF TA+V
Sbjct 795 LQVAQLYPIAIFIKPRSIESLMEM----NKRLTEEQAKKTYDRAMKLEQEFGEYF-TALV 849
Query 645 NSD-LDKAYQELLRLINKLDTEPQWVPS 671
D L+ Y + +I + W+PS
Sbjct 850 QGDTLEDIYNQCKMVIEEQSGPYIWIPS 877
Score = 36.2 bits (82), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
Query 254 VKIVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
+K+++ K + V N+ +S+ +++I+ GGAA+K G L GD +L +N
Sbjct 251 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVN 306
>sp|Q5PYH5|DLG1L_DANRE Discs large homolog 1-like protein OS=Danio
rerio OX=7955 GN=dlg1l PE=2 SV=1
Length=827
Score = 191 bits (486), Expect = 2e-50, Method: Compositional matrix adjust.
Identities = 139/438 (32%), Positives = 219/438 (50%), Gaps = 77/438 (18%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ + IS I+ GG A+ G L +GD ++ +NGI++RG + L + T+T V
Sbjct 424 EGIFISFILAGGPADLCGELRKGDRLVSVNGIDLRGATHEQAAAALKNAGQTVTIV---- 479
Query 336 QQIKPP-----------------------------PAKETVIHVKAHFDYDPSDDPYVPC 366
Q +P +++ ++V+A FDYD + D +P
Sbjct 480 AQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPS 539
Query 367 RELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEED 426
+ GL+F+ GDILHV++ D WWQA + + G++P K +++E
Sbjct 540 Q--GLNFKFGDILHVVNASDDEWWQARQVTAQGEVEEMGVIPSKRRVEKKE--------- 588
Query 427 KEPEKSGKLWCAKKNKKKRKKVLYNANKNDDY-------DNEEILTYEEMSLYHQPANRK 479
+L K N K R+K + DD E +L+YE +S Q N
Sbjct 589 -----RARLKTVKFNSKSREK----GDNPDDMLSKGQSGQEEYVLSYEPVS--QQEVNYS 637
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFV-SRQAFEA 538
RP+I++GP ++ + L+++ D+F S VPHTTR +RD EV GRDYHFV SR+ E
Sbjct 638 RPVIILGPM---KDRVNDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVVSREQMER 694
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
DI KFIE G++ +LYGTS+ SVR+V GK C+L + ++K L+ + L P IFI
Sbjct 695 DIQEHKFIEAGQYNSHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQVAMLYPIGIFIK 754
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD-LDKAYQELLR 657
P S E + + K E+ R+ ++ ++EQ +F TAIV D L++ Y ++ +
Sbjct 755 PKSVENIMEM----NKRLTEEQGRKTYDRAMKLEQEFMEHF-TAIVQGDTLEEIYDQVKQ 809
Query 658 LINKLDTEPQWVPSTWLR 675
+I E Q P W++
Sbjct 810 II-----EEQSGPYIWVQ 822
Score = 36.2 bits (82), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 33/56 (59%), Gaps = 4/56 (7%)
Query 254 VKIVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
+K+++ K + V N+ +S+ +++I++GGAA K G L GD++L +N
Sbjct 255 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLLAVN 310
>sp|Q62696|DLG1_RAT Disks large homolog 1 OS=Rattus norvegicus
OX=10116 GN=Dlg1 PE=1 SV=1
Length=911
Score = 189 bits (480), Expect = 2e-49, Method: Compositional matrix adjust.
Identities = 135/438 (31%), Positives = 217/438 (50%), Gaps = 58/438 (13%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ + IS I+ GG A+ SG L +GD ++ +N +++R + L + +T V
Sbjct 486 EGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAVTIV---- 541
Query 336 QQIKPP-----------------------------PAKETVIHVKAHFDYDPSDDPYVPC 366
Q +P +++ ++V+A FDYD + D +P
Sbjct 542 AQYRPEEYSRFEAKIHDLRETMMNSSVSSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPS 601
Query 367 RELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQRE-AMKQTIEE 425
+ GL+F+ GDILHVI+ D WWQA + + G++P K +++E A +T++
Sbjct 602 Q--GLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEKKERARLKTVKF 659
Query 426 DKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDY----------DNEEILTYEEMSLYHQP 475
+ + K K V NA+ ++ E +L+YE ++ Q
Sbjct 660 NSKTRGDKGEIPDDMGSKGLKHVTSNASDSESSYHEYGCSKGGQEEYVLSYEPVN--QQE 717
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFV-SRQ 534
N RP+I++GP ++ + L+++ D+F S VPHTTR +RD EV GRDYHFV SR+
Sbjct 718 VNYTRPVIILGPM---KDRVNDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSRE 774
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
E DI KFIE G++ +LYGTS+ SVR V GK C+L + ++K L+ + L P
Sbjct 775 QMEKDIQEHKFIEAGQYNNHLYGTSVQSVRAVAEKGKHCILDVSGNAIKRLQIAQLYPIS 834
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD-LDKAYQ 653
IFI P S E + + K E+ R+ E+ +EQ +F TAIV D L+ Y
Sbjct 835 IFIKPKSMENIMEM----NKRLTDEQARKTFERAVRLEQEFTEHF-TAIVQGDTLEDIYN 889
Query 654 ELLRLINKLDTEPQWVPS 671
++ ++I + WVP+
Sbjct 890 QVKQIIEEQSGPYIWVPA 907
Score = 37.0 bits (84), Expect = 0.65, Method: Compositional matrix adjust.
Identities = 17/58 (29%), Positives = 34/58 (59%), Gaps = 4/58 (7%)
Query 254 VKIVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
+K+++ K + V N+ +S+ +++I++GGAA K G L GD++L +N +
Sbjct 319 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSV 376
>sp|P78352|DLG4_HUMAN Disks large homolog 4 OS=Homo sapiens OX=9606
GN=DLG4 PE=1 SV=3
Length=724
Score = 187 bits (475), Expect = 2e-49, Method: Compositional matrix adjust.
Identities = 130/428 (30%), Positives = 202/428 (47%), Gaps = 73/428 (17%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ + IS I+ GG A+ SG L +GD++L +NG+++R + L + T+T +
Sbjct 334 EGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTII---- 389
Query 336 QQIKPPPAK--ETVIH---------------------------VKAHFDYDPSDDPYVPC 366
Q KP E IH ++A FDYD + D C
Sbjct 390 AQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKD----C 445
Query 367 REL--GLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIE 424
L LSF+ GD+LHVI D WWQA R + G +P K ++RE +
Sbjct 446 GFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRL--- 502
Query 425 EDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIIL 484
K W + + R+ + +L+YE ++ + RPII+
Sbjct 503 -------KAKDWGSSSGSQGRE--------------DSVLSYETVT--QMEVHYARPIII 539
Query 485 IGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVS-RQAFEADIAAG 543
+GP N+ L+++ D+F S VPHTTR +R+ E+ GRDYHFVS R+ E DI A
Sbjct 540 LGPTKDRAND---DLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAH 596
Query 544 KFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQE 603
KFIE G++ +LYGTS+ SVR+V GK C+L + +++ L+ + L P IFI P S E
Sbjct 597 KFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLE 656
Query 604 RLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLD 663
+ + K E+ R+ ++ ++EQ F + ++ Y ++ R+I L
Sbjct 657 NVLEI----NKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLS 712
Query 664 TEPQWVPS 671
WVP+
Sbjct 713 GPYIWVPA 720
Score = 37.7 bits (86), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 17/60 (28%), Positives = 35/60 (58%), Gaps = 4/60 (7%)
Query 254 VKIVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+K+++ K + V N+ +S+ +++I++GGAA K G L GD++L +N + +
Sbjct 161 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGL 220
>sp|Q62108|DLG4_MOUSE Disks large homolog 4 OS=Mus musculus OX=10090
GN=Dlg4 PE=1 SV=1
Length=724
Score = 187 bits (474), Expect = 3e-49, Method: Compositional matrix adjust.
Identities = 130/428 (30%), Positives = 201/428 (47%), Gaps = 73/428 (17%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ + IS I+ GG A+ SG L +GD++L +NG+++R + L + T+T +
Sbjct 334 EGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTII---- 389
Query 336 QQIKPPPAK--ETVIH---------------------------VKAHFDYDPSDDPYVPC 366
Q KP E IH ++A FDYD + D C
Sbjct 390 AQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKD----C 445
Query 367 REL--GLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIE 424
L LSF GD+LHVI D WWQA R + G +P K ++RE +
Sbjct 446 GFLSQALSFHFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRL--- 502
Query 425 EDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIIL 484
K W + + R+ + +L+YE ++ + RPII+
Sbjct 503 -------KAKDWGSSSGSQGRE--------------DSVLSYETVT--QMEVHYARPIII 539
Query 485 IGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVS-RQAFEADIAAG 543
+GP N+ L+++ D+F S VPHTTR +R+ E+ GRDYHFVS R+ E DI A
Sbjct 540 LGPTKDRAND---DLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAH 596
Query 544 KFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQE 603
KFIE G++ +LYGTS+ SVR+V GK C+L + +++ L+ + L P IFI P S E
Sbjct 597 KFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLE 656
Query 604 RLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLD 663
+ + K E+ R+ ++ ++EQ F + ++ Y ++ R+I L
Sbjct 657 NVLEI----NKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLS 712
Query 664 TEPQWVPS 671
WVP+
Sbjct 713 GPYIWVPA 720
Score = 37.7 bits (86), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 17/60 (28%), Positives = 35/60 (58%), Gaps = 4/60 (7%)
Query 254 VKIVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+K+++ K + V N+ +S+ +++I++GGAA K G L GD++L +N + +
Sbjct 161 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGL 220
>sp|P31016|DLG4_RAT Disks large homolog 4 OS=Rattus norvegicus
OX=10116 GN=Dlg4 PE=1 SV=1
Length=724
Score = 186 bits (473), Expect = 4e-49, Method: Compositional matrix adjust.
Identities = 130/428 (30%), Positives = 202/428 (47%), Gaps = 73/428 (17%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ + IS I+ GG A+ SG L +GD++L +NG+++R + L + T+T +
Sbjct 334 EGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTII---- 389
Query 336 QQIKPPPAK--ETVIH---------------------------VKAHFDYDPSDDPYVPC 366
Q KP E IH ++A FDYD + D C
Sbjct 390 AQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKD----C 445
Query 367 REL--GLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIE 424
L LSF+ GD+LHVI D WWQA R + G +P K ++RE +
Sbjct 446 GFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRL--- 502
Query 425 EDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIIL 484
K W + + R+ + +L+YE ++ + RPII+
Sbjct 503 -------KAKDWGSSSGSQGRE--------------DSVLSYETVT--QMEVHYARPIII 539
Query 485 IGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVS-RQAFEADIAAG 543
+GP N+ L+++ D+F S VPHTTR +R+ E+ GRDYHFVS R+ E DI A
Sbjct 540 LGPTKDRAND---DLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAH 596
Query 544 KFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQE 603
KFIE G++ +LYGTS+ SVR+V GK C+L + +++ L+ + L P IFI P S E
Sbjct 597 KFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLE 656
Query 604 RLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLD 663
+ + K E+ R+ ++ ++EQ F + ++ Y ++ R+I L
Sbjct 657 NVLEI----NKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLS 712
Query 664 TEPQWVPS 671
WVP+
Sbjct 713 GPYIWVPA 720
Score = 37.7 bits (86), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 17/60 (28%), Positives = 35/60 (58%), Gaps = 4/60 (7%)
Query 254 VKIVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+K+++ K + V N+ +S+ +++I++GGAA K G L GD++L +N + +
Sbjct 161 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGL 220
>sp|Q28C55|DLG1_XENTR Disks large homolog 1 OS=Xenopus tropicalis
OX=8364 GN=dlg1 PE=2 SV=1
Length=927
Score = 187 bits (475), Expect = 1e-48, Method: Compositional matrix adjust.
Identities = 135/453 (30%), Positives = 226/453 (50%), Gaps = 73/453 (16%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ + IS I+ GG A+ SG L +GD ++ +NG++++ + L + T+T V
Sbjct 487 EGIFISFILAGGPADLSGELQKGDRIMSVNGVDLKSATHEQAAAALKNAGQTVTIV---- 542
Query 336 QQIKPP-----------------------------PAKETVIHVKAHFDYDPSDDPYVPC 366
Q +P +++ ++V+A FDYD + D +P
Sbjct 543 AQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPS 602
Query 367 RELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSF--QQQREAMKQTIE 424
+ GL+F+ GDILHV++ D WWQA + + G++P K +++R +K
Sbjct 603 Q--GLNFKFGDILHVVNASDDEWWQARQVTADGESEEIGVIPSKRRVEKKERARLKTVKF 660
Query 425 EDKEPEKSGKLWCAKKNKK--KRKKVLY-----------------NANKNDD---YDNEE 462
K G+ + K+ K RK Y +N +D Y +E
Sbjct 661 NSKARGDKGQSFNDKRKKNLFSRKFPFYKNKDQSEMETSDVDQHVTSNASDSESSYRGQE 720
Query 463 --ILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRD 520
+L+YE ++ Q N RP+I++GP ++ + L+++ ++F S VPHTTR +RD
Sbjct 721 EYVLSYEPVN--QQEVNYSRPVIILGPT---KDRVNDDLISEFPEKFGSCVPHTTRPKRD 775
Query 521 QEVAGRDYHFV-SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRT 579
E+ GRDYHFV SR+ E DI +FIE G++ +LYGTS+ SV++V GK C+L +
Sbjct 776 YEIDGRDYHFVTSREQMEKDIQDHRFIEAGQYNSHLYGTSVQSVKEVAERGKHCILDVSG 835
Query 580 QSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYF 639
++K L+ + L P IFI P S E + + K E+ R+ E+ ++EQ +F
Sbjct 836 NAIKRLQIAQLYPIAIFIKPKSVENIIEM----SKRVTEEQGRKTYERAMKLEQEFTEHF 891
Query 640 DTAIVNSD-LDKAYQELLRLINKLDTEPQWVPS 671
TAIV D L++ Y ++ ++I + + WVP+
Sbjct 892 -TAIVQGDTLEEIYNQIKQIIEEQSSTFIWVPA 923
Score = 37.4 bits (85), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 18/58 (31%), Positives = 34/58 (59%), Gaps = 4/58 (7%)
Query 254 VKIVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
+K+V+ K + V N+ +S+ +++I++GGAA K G L GD++L +N +
Sbjct 319 IKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLLAVNTV 376
>sp|Q6P7F1|MPP4_MOUSE MAGUK p55 subfamily member 4 OS=Mus musculus
OX=10090 GN=Mpp4 PE=1 SV=1
Length=635
Score = 181 bits (458), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 93/222 (42%), Positives = 135/222 (61%), Gaps = 17/222 (8%)
Query 466 YEEMSLYH-QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVA 524
YEE+ Y QPA++ R I+L+GP G NELR++L+ F SAVPHTTR + E+
Sbjct 412 YEEVVRYQRQPADKHRLIVLVGPSGVGVNELRRQLIGCNPSCFQSAVPHTTRFPKSYEMD 471
Query 525 GRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKT 584
GR+YH+VSR+ FE+ + K +E+GE++ +LYGTS+++V V++ GKIC++ L Q +++
Sbjct 472 GREYHYVSRETFESLMYGHKMLEYGEYKGHLYGTSVNAVHAVLDEGKICIMDLEPQDIQS 531
Query 585 LRNSDLKPYIIFIAPPSQERLRALLAKEGKNP------------KPEELREIIEKTREME 632
R DLKPY+IFI PP+ +R KN K E+L+E+ E ++ME
Sbjct 532 ARTRDLKPYVIFIKPPNTSSMR----HSRKNAKITTDYYVDMKFKDEDLQEMEELAQKME 587
Query 633 QNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
G +FD IVN +L A +LL I K E QWVP W+
Sbjct 588 SQFGQFFDHVIVNDNLQDACGQLLSAIQKAQEELQWVPEAWV 629
Score = 155 bits (392), Expect = 1e-38, Method: Compositional matrix adjust.
Identities = 99/277 (36%), Positives = 159/277 (57%), Gaps = 18/277 (6%)
Query 147 ISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVL-KPVHHKEG 205
+ LL L+ + Q K+++ + K P ++AQ LA EV +L K E
Sbjct 49 LCLLYDLLHSPWLQALLKVYDCLQRFKEKKL--VPDTTHAQILACEVLELLPKASGSPEI 106
Query 206 QELTALLNTPHIQALLLAHDKVAEQEMQ-LEPITDERVYESIGQYGGETVKIVRIEKARD 264
QEL +L PH +ALL AHD VA+++ + L P + + +S E ++IV + K +
Sbjct 107 QELRQVLQAPHCKALLSAHDTVAQKDFEPLLPPLPDNIPDS-----EEAMRIVCLVKNQQ 161
Query 265 IPLGATV-RNEMDS-VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
PLGAT+ R+E+ ++++R++ GG E+SGLL+ GD+++E+NG+ + G D +V +L+
Sbjct 162 -PLGATIKRHEITGDILVARVIHGGLVERSGLLYAGDKLVEVNGVSVEGLDPEQVIHILA 220
Query 323 DMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVI 382
GT+ F +IP PP + + +++V+A DY P +DP +PC + GL F KGDIL ++
Sbjct 221 MSCGTIMFKVIPVS--APPVSSQKMVYVRAMIDYWPQEDPDIPCMDAGLPFLKGDILQIV 278
Query 383 SQEDPNWWQAYREGDEDNQPLAGLVPGKSF--QQQRE 417
Q D WWQA + D AGL+P ++QRE
Sbjct 279 DQNDALWWQARKISDLTI--CAGLIPSNHLLKRKQRE 313
>sp|P31007|DLG1_DROME Disks large 1 tumor suppressor protein OS=Drosophila
melanogaster OX=7227 GN=dlg1 PE=1 SV=2
Length=970
Score = 182 bits (462), Expect = 5e-47, Method: Compositional matrix adjust.
Identities = 135/449 (30%), Positives = 221/449 (49%), Gaps = 64/449 (14%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL---- 332
+ +S I+ GG A+ L GD++L +N + + E L G +T +
Sbjct 528 GIYVSFILAGGPADLGSELKRGDQLLSVNNVNLTHATHEEAAQALKTSGGVVTLLAQYRP 587
Query 333 -------IPSQQIKPPPA-------------KETVIHVKAHFDYDPSDDPYVPCRELGLS 372
Q++K A ++ ++V+A FDYDP+ D +P R GL
Sbjct 588 EEYNRFEARIQELKQQAALGAGGSGTLLRTTQKRSLYVRALFDYDPNRDDGLPSR--GLP 645
Query 373 FQKGDILHVISQEDPNWWQAYRE-GDEDNQPLAGLVPGKS-FQQQREAMKQTIE------ 424
F+ GDILHV + D WWQA R GD +++ + G+VP K ++++ A ++++
Sbjct 646 FKHGDILHVTNASDDEWWQARRVLGDNEDEQI-GIVPSKRRWERKMRARDRSVKFQGHAA 704
Query 425 EDKEPEKSGKLWCAKKNKKKRKKVLYNAN---KNDDYDNEE--ILTY-----------EE 468
+ +K L KKN +K + + KN+D ++E +L Y EE
Sbjct 705 ANNNLDKQSTLDRKKKNFTFSRKFPFMKSRDEKNEDGSDQEPFMLCYTQDDANAEGASEE 764
Query 469 MSLYHQPANR-----KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV 523
L ++ R RP+I++GP ++ + L+++ D+F S VPHTTR +R+ EV
Sbjct 765 NVLSYEAVQRLSINYTRPVIILGPL---KDRINDDLISEYPDKFGSCVPHTTRPKREYEV 821
Query 524 AGRDYHFVS-RQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSL 582
GRDYHFVS R+ E DI FIE G++ NLYGTS+ SVR+V GK C+L + ++
Sbjct 822 DGRDYHFVSSREQMERDIQNHLFIEAGQYNDNLYGTSVASVREVAEKGKHCILDVSGNAI 881
Query 583 KTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTA 642
K L+ + L P +FI P S + + + + E+ ++ E+ +MEQ G YF
Sbjct 882 KRLQVAQLYPVAVFIKPKSVDSVMEM----NRRMTEEQAKKTYERAIKMEQEFGEYFTGV 937
Query 643 IVNSDLDKAYQELLRLINKLDTEPQWVPS 671
+ +++ Y ++ +I WVPS
Sbjct 938 VQGDTIEEIYSKVKSMIWSQSGPTIWVPS 966
>sp|Q96JB8|MPP4_HUMAN MAGUK p55 subfamily member 4 OS=Homo sapiens
OX=9606 GN=MPP4 PE=1 SV=2
Length=637
Score = 177 bits (448), Expect = 4e-46, Method: Compositional matrix adjust.
Identities = 90/218 (41%), Positives = 137/218 (63%), Gaps = 9/218 (4%)
Query 466 YEEMSLYHQ-PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVA 524
YEE+ Y + P+++ R I+L+GP G NELR++L+ F SAVPHTTR+++ E+
Sbjct 413 YEEVVRYQRRPSDKYRLIVLMGPSGVGVNELRRQLIEFNPSHFQSAVPHTTRTKKSYEMN 472
Query 525 GRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKT 584
GR+YH+VS++ FE I + + +E+GE++ +LYGTS+D+V+ V+ GKIC++ L Q ++
Sbjct 473 GREYHYVSKETFENLIYSHRMLEYGEYKGHLYGTSVDAVQTVLVEGKICVMDLEPQDIQG 532
Query 585 LRNSDLKPYIIFIAPPS-----QERLRALLAKE---GKNPKPEELREIIEKTREMEQNNG 636
+R +LKPY+IFI P + Q R A + + K E+L+E+ + ME G
Sbjct 533 VRTHELKPYVIFIKPSNMRCMKQSRKNAKVITDYYVDMKFKDEDLQEMENLAQRMETQFG 592
Query 637 HYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
+FD IVN L A +LL I K EPQWVP+TW+
Sbjct 593 QFFDHVIVNDSLHDACAQLLSAIQKAQEEPQWVPATWI 630
Score = 160 bits (406), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 101/277 (36%), Positives = 159/277 (57%), Gaps = 18/277 (6%)
Query 147 ISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPV-HHKEG 205
+ LL L+ + Q KI++ + K P +AQ L+ EV +L+ E
Sbjct 50 VCLLYDLLHSPWLQALLKIYDCLQEFKEKKL--VPATPHAQVLSYEVVELLRETPTSPEI 107
Query 206 QELTALLNTPHIQALLLAHDKVAEQEMQ-LEPITDERVYESIGQYGGETVKIVRIEKARD 264
QEL +L PH +ALL AHD +A+++ + L P + + ES E ++IV + K +
Sbjct 108 QELRQMLQAPHFKALLSAHDTIAQKDFEPLLPPLPDNIPES-----EEAMRIVCLVKNQQ 162
Query 265 IPLGATV-RNEMDS-VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
PLGAT+ R+EM ++++RI+ GG AE+SGLL+ GD+++E+NG+ + G D +V +L+
Sbjct 163 -PLGATIKRHEMTGDILVARIIHGGLAERSGLLYAGDKLVEVNGVSVEGLDPEQVIHILA 221
Query 323 DMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVI 382
GT+ F ++P PP + +++V+A +Y P +DP +PC + GL FQKGDIL ++
Sbjct 222 MSRGTIMFKVVPVSD--PPVNSQQMVYVRAMTEYWPQEDPDIPCMDAGLPFQKGDILQIV 279
Query 383 SQEDPNWWQAYREGDEDNQPLAGLVPGKSF--QQQRE 417
Q D WWQA + D AGLVP ++QRE
Sbjct 280 DQNDALWWQARKISDPAT--CAGLVPSNHLLKRKQRE 314
>sp|G5ECY0|DLG1_CAEEL Disks large homolog 1 OS=Caenorhabditis
elegans OX=6239 GN=dlg-1 PE=1 SV=1
Length=967
Score = 175 bits (444), Expect = 1e-44, Method: Compositional matrix adjust.
Identities = 128/440 (29%), Positives = 215/440 (49%), Gaps = 54/440 (12%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG--TLTFVLIPS 335
+ IS ++ GG A+ SG + GD +LE+NG+ +R E + L + LT P
Sbjct 533 IYISFVLPGGVADLSGNVKTGDVLLEVNGVVLRNATHKEAAEALRNAGNPVYLTLQYRPQ 592
Query 336 Q----QIKPPPAKETVI-------------HVKAHFDYDPS-DDPYVPCRELGLSFQKGD 377
+ + K + VI +V+A FDYDPS ++ P R +G F GD
Sbjct 593 EYQIFESKIEKLRNDVIAQSRMGTLSRKSEYVRALFDYDPSRENSVAPHRSMG--FNYGD 650
Query 378 ILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQ---------------- 421
ILH+I+ D WW A + + + G++P K ++RE +++
Sbjct 651 ILHIINSSDDEWWTARKVHENGEETAEGVIPSKKRVEKRERLRRKQVNFNSGSQSLGRNS 710
Query 422 --TIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEE-ILTYEEMSLYHQPANR 478
T E++ +S + K K L + N+ EE + +Y+ ++ Q N
Sbjct 711 STTGLENRRGSRSQLSFSRKFPFVKSTDRLNDLNEESSNVAEEPVWSYQ--AVEQQAINY 768
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
RP+I++G ++ + L+N++ +F+S VPHT+R R+ EV GRDY+FV++ E
Sbjct 769 VRPVIILGAL---KDRINDELVNRDPSKFSSCVPHTSRPPREGEVNGRDYYFVNKHNMEE 825
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLR-NSDLKPYIIFI 597
D+ FIE G+F+ NLYGTSI SVR V N G+ C+L + +++ L+ N++++P IFI
Sbjct 826 DVKNNLFIEAGQFQNNLYGTSIQSVRDVANQGRHCILDVSGNAIRRLQSNANIQPISIFI 885
Query 598 APPSQERLRALLAKEGKNPK------PEELREIIEKTREMEQNNGHYFDTAIVN-SDLDK 650
P S +++ L ++ N + EE + + +EQ G F I N +
Sbjct 886 KPSSAQQILELDSQLATNRQDDRAMSGEEAQAQYSRCHRIEQTFGDLFTQEISNVHSAND 945
Query 651 AYQELLRLINKLDTEPQWVP 670
++ +I++ P WVP
Sbjct 946 VLSKVYSIISRESQTPIWVP 965
>sp|Q6R005|DLG4_DANRE Disks large homolog 4 OS=Danio rerio OX=7955
GN=dlg4 PE=2 SV=1
Length=801
Score = 163 bits (412), Expect = 9e-41, Method: Compositional matrix adjust.
Identities = 114/422 (27%), Positives = 198/422 (47%), Gaps = 64/422 (15%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV---- 331
+ + IS I+ GGAA+ SG L +GD++L +NG+++R + L + T+T +
Sbjct 414 EGIFISFILAGGAADLSGELRKGDQILSVNGVDLRHATHEQAAAALKNAGQTVTIITQYR 473
Query 332 -----------------LIPSQQIKPPPAKET---VIHVKAHFDYDPSDDPYVPCRELGL 371
L+ S + + + ++A FDYD + D + +
Sbjct 474 PEEYSRFEAKIHDLREQLMNSSLVSAAASLRSGKRSFFIRALFDYDKTADGGFLSQ--AV 531
Query 372 SFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEK 431
SF+ GD+L V D WWQA + G +P K +++E
Sbjct 532 SFRFGDVLQVFDCSDEEWWQAGKLAPHGELEETGYIPSKRRVERKE-------------- 577
Query 432 SGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCG 491
W K + + + DY I++YE ++ + RP+I++GP
Sbjct 578 ----WSRLKTRGREP-----VSGRSDY----IVSYETVT--QSEVHYARPVIILGPS--- 619
Query 492 QNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFV-SRQAFEADIAAGKFIEHGE 550
++ + L+++ D+F S VPHTTR +R+ E+ GRDYHFV SR+ E DI + +FIE G+
Sbjct 620 KDRVNDDLLSEFPDKFGSCVPHTTRPKREYEMDGRDYHFVSSREQMEKDIQSHRFIEAGQ 679
Query 551 FEKNLYGTSIDSVRQVI-NSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALL 609
+ +LYGTS+ SVRQV GK C+L + +++ L+ + L P IFI P S + + +
Sbjct 680 YNSHLYGTSVQSVRQVAEQQGKHCILDVSANAVRRLQAAQLYPIAIFIRPSSLQNVLNI- 738
Query 610 AKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWV 669
K E+ R +++ ++EQ+ F + ++ Y + +I + W+
Sbjct 739 ---SKRLTEEQARRALDRAVKLEQDFIECFSAIVEGESFEEIYHHVKSVIEEQSGPYIWI 795
Query 670 PS 671
P+
Sbjct 796 PA 797
Score = 36.6 bits (83), Expect = 0.82, Method: Compositional matrix adjust.
Identities = 17/60 (28%), Positives = 35/60 (58%), Gaps = 4/60 (7%)
Query 254 VKIVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+K+++ K + V N+ +S+ +++I++GGAA K G L GD++L +N + +
Sbjct 249 LKLIKGPKGLGFSIAGGVGNQHVPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNNMYL 308
>sp|Q64520|KGUA_MOUSE Guanylate kinase OS=Mus musculus OX=10090
GN=Guk1 PE=1 SV=2
Length=198
Score = 135 bits (340), Expect = 2e-35, Method: Compositional matrix adjust.
Identities = 73/183 (40%), Positives = 108/183 (59%), Gaps = 13/183 (7%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
RP++L GP G++ L ++L + F +V HTTR+ R E G+DY+FV+R+ + D
Sbjct 5 RPVVLSGPSGAGKSTLLKKLFQEHSSIFGFSVSHTTRNPRPGEEDGKDYYFVTREMMQRD 64
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
IAAG FIEH EF NLYGTS ++VR V +IC+L + Q +++++ +DL P IF+ P
Sbjct 65 IAAGDFIEHAEFSGNLYGTSKEAVRAVQAMNRICVLDVDLQGVRSIKKTDLCPIYIFVQP 124
Query 600 PS----QERLRALLAKEGKNPKPEE--LREIIEKTREMEQNN-GHYFDTAIVNSDLDKAY 652
PS ++RLR +N + EE + + +ME + FD I+N DLDKAY
Sbjct 125 PSLDVLEQRLRL------RNTETEESLAKRLAAARTDMESSKEPGLFDLVIINDDLDKAY 178
Query 653 QEL 655
L
Sbjct 179 ATL 181
>sp|P46195|KGUA_BOVIN Guanylate kinase OS=Bos taurus OX=9913 GN=GUK1
PE=1 SV=2
Length=198
Score = 133 bits (334), Expect = 2e-34, Method: Compositional matrix adjust.
Identities = 69/177 (39%), Positives = 101/177 (57%), Gaps = 1/177 (1%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
RP++L GP G++ L ++L+ + F +V HTTR R E G+DY+FV+R+ + D
Sbjct 5 RPVVLSGPSGAGKSTLLKKLLQEHGSIFGFSVSHTTRDPRPGEENGKDYYFVTREVMQRD 64
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
IAAG FIEH EF NLYGTS +VR V +IC+L + Q ++ ++ +DL+P IF+ P
Sbjct 65 IAAGDFIEHAEFSGNLYGTSKAAVRAVQAMNRICVLDVDLQGVRNIKKTDLRPIYIFVQP 124
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNN-GHYFDTAIVNSDLDKAYQEL 655
PS + L L + + + + +ME + FD IVN LDKAY L
Sbjct 125 PSLDVLEQRLRQRNTETEESLAKRLAAARADMESSKEPGLFDLIIVNDSLDKAYWAL 181
>sp|P31006|KGUA_PIG Guanylate kinase OS=Sus scrofa OX=9823 GN=GUK1
PE=1 SV=2
Length=198
Score = 132 bits (333), Expect = 3e-34, Method: Compositional matrix adjust.
Identities = 68/177 (38%), Positives = 101/177 (57%), Gaps = 1/177 (1%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
RP++L GP G++ L ++L+ + F +V HTTR R E G+DY+FV+R+ + D
Sbjct 5 RPVVLSGPSGAGKSTLLKKLLQEHSSIFGFSVSHTTRDPRPGEENGKDYYFVTREVMQRD 64
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
IAAG FIEH EF NLYGTS +VR V +IC+L + Q ++ ++ +DL+P IF+ P
Sbjct 65 IAAGDFIEHAEFSGNLYGTSKAAVRAVQAMNRICVLDVDLQGVRNIKKTDLQPIYIFVQP 124
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNN-GHYFDTAIVNSDLDKAYQEL 655
PS + L L + + + + +ME + FD I+N LDKAY L
Sbjct 125 PSLDVLEQRLRQRNTETEESLAKRLAAAKADMESSKEPGLFDLIIINDSLDKAYWAL 181
>sp|Q16774|KGUA_HUMAN Guanylate kinase OS=Homo sapiens OX=9606
GN=GUK1 PE=1 SV=2
Length=197
Score = 131 bits (330), Expect = 7e-34, Method: Compositional matrix adjust.
Identities = 67/177 (38%), Positives = 102/177 (58%), Gaps = 1/177 (1%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
RP++L GP G++ L +RL+ + F +V HTTR+ R E G+DY+FV+R+ + D
Sbjct 5 RPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENGKDYYFVTREVMQRD 64
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
IAAG FIEH EF NLYGTS +V+ V +IC+L + Q ++ ++ +DL+P I + P
Sbjct 65 IAAGDFIEHAEFSGNLYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPIYISVQP 124
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNN-GHYFDTAIVNSDLDKAYQEL 655
PS L L + + ++ + +ME + FD I+N LD+AY EL
Sbjct 125 PSLHVLEQRLRQRNTETEESLVKRLAAAQADMESSKEPGLFDVVIINDSLDQAYAEL 181
>sp|Q2QPW1|GMK1_ORYSJ Guanylate kinase 1 OS=Oryza sativa subsp.
japonica OX=39947 GN=GK1 PE=2 SV=2
Length=382
Score = 129 bits (324), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 63/183 (34%), Positives = 104/183 (57%), Gaps = 1/183 (1%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
++PI++ GP G+ L +LM + +F +V HTTR+ R++E+ G YHF R E
Sbjct 128 QKPIVISGPSGVGKGTLIAKLMKEYPSKFGFSVSHTTRAPREKEIDGVHYHFTERSKIEE 187
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+I+ GKF+E N+YGTS+++V V + GK C+L + Q +++R S L+ IF+
Sbjct 188 EISEGKFLEFAHVHGNVYGTSVEAVESVTDEGKRCILDIDVQGARSVRASSLEAIFIFVC 247
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNG-HYFDTAIVNSDLDKAYQELLR 657
PPS E L L G + + + + E++Q+N FD +VN DL+ Y+ L +
Sbjct 248 PPSFEELEKRLRARGTETEEQIQKRLRNARAELDQSNSPGLFDHLLVNDDLEACYENLKK 307
Query 658 LIN 660
L++
Sbjct 308 LLS 310
>sp|Q5PYH6|DLG1_DANRE Disks large homolog 1 OS=Danio rerio OX=7955
GN=dlg1 PE=2 SV=2
Length=873
Score = 133 bits (334), Expect = 7e-31, Method: Compositional matrix adjust.
Identities = 79/210 (38%), Positives = 124/210 (59%), Gaps = 12/210 (6%)
Query 463 ILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQE 522
+L+YE ++ Q + RP+I++GP ++ + L+++ D+F S VPHTTR +RD E
Sbjct 669 VLSYETVT--QQEVSYSRPVIILGPM---KDRINDDLISEFPDKFGSCVPHTTRPKRDYE 723
Query 523 VAGRDYHFV-SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS 581
V GRDYHFV SR+ E DI KFIE G++ +LYGTS+ SVR+V GK C+L + +
Sbjct 724 VDGRDYHFVNSREQMEKDIQDHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNA 783
Query 582 LKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDT 641
+K L+ + L P +FI P S E + + K E+ R+ ++ ++EQ +F T
Sbjct 784 IKRLQLAQLYPIAVFIKPKSVENILEM----NKRLMEEQGRKTYDRAMKLEQEFLEHF-T 838
Query 642 AIVNSD-LDKAYQELLRLINKLDTEPQWVP 670
AIV D L++ Y ++ ++I + WVP
Sbjct 839 AIVQGDTLEEIYNQVKQIIEEQSGPFIWVP 868
Score = 39.7 bits (91), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 20/58 (34%), Positives = 34/58 (59%), Gaps = 4/58 (7%)
Query 254 VKIVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
VK+V+ K + V N+ +S+ I++I++GGAA K G L GD++L +N +
Sbjct 326 VKLVKGPKGLGFSIAGGVGNQHIPGDNSIYITKIIEGGAAHKDGRLQIGDKLLAVNAV 383
Score = 37.4 bits (85), Expect = 0.53, Method: Compositional matrix adjust.
Identities = 16/56 (29%), Positives = 31/56 (55%), Gaps = 0/56 (0%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV 331
+ + IS I+ GG A+ G L +GD ++ +NG+++R + L + T+T +
Sbjct 495 EGIFISFILAGGPADLCGELRKGDRIVSVNGVDLRSATHEQAAAALKNAGQTVTII 550
>sp|P15454|KGUA_YEAST Guanylate kinase OS=Saccharomyces cerevisiae
(strain ATCC 204508 / S288c) OX=559292 GN=GUK1 PE=1 SV=2
Length=187
Score = 120 bits (301), Expect = 4e-30, Method: Composition-based stats.
Identities = 68/181 (38%), Positives = 101/181 (56%), Gaps = 1/181 (1%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
RPI++ GP G++ L ++L + D F +V TTR+ R EV G+DY+FVS F++
Sbjct 3 RPIVISGPSGTGKSTLLKKLFAEYPDSFGFSVSSTTRTPRAGEVNGKDYNFVSVDEFKSM 62
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN-SDLKPYIIFIA 598
I +FIE +F N YG+++ SV+QV SGK C+L + Q +K+++ +L +FIA
Sbjct 63 IKNNEFIEWAQFSGNYYGSTVASVKQVSKSGKTCILDIDMQGVKSVKAIPELNARFLFIA 122
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS E L+ L G + + + E+ D IVN DLDKAY+EL
Sbjct 123 PPSVEDLKKRLEGRGTETEESINKRLSAAQAELAYAETGAHDKVIVNDDLDKAYKELKDF 182
Query 659 I 659
I
Sbjct 183 I 183
>sp|P93757|GMK1_ARATH Guanylate kinase 1 OS=Arabidopsis thaliana
OX=3702 GN=GK-1 PE=1 SV=3
Length=387
Score = 118 bits (295), Expect = 2e-27, Method: Compositional matrix adjust.
Identities = 62/186 (33%), Positives = 98/186 (53%), Gaps = 1/186 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
N ++PI++ GP G+ L LM + F +V HTTRS R E+ G YHF ++
Sbjct 134 GNAEKPIVISGPSGVGKGTLISMLMKEFPSMFGFSVSHTTRSPRSMEMDGVHYHFADKKV 193
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
E +I GKF+E NLYGTSI+SV V +SGK C+L + Q +++R S L I
Sbjct 194 MEKEIKDGKFLEFASVHGNLYGTSIESVEAVTDSGKRCILDIDVQGARSVRASSLDAIFI 253
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQN-NGHYFDTAIVNSDLDKAYQE 654
F+ PPS + L L G + + + + E+++ + F + N +L++ Y++
Sbjct 254 FVCPPSMKELEDRLRARGTETEEQIQKRLRNAEAEIKEGISSGIFGLILYNDNLEECYKK 313
Query 655 LLRLIN 660
L L+
Sbjct 314 LKNLLG 319
>sp|Q9P6I5|KGUA_SCHPO Guanylate kinase OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=SPBC1198.05 PE=3
SV=1
Length=202
Score = 112 bits (279), Expect = 5e-27, Method: Compositional matrix adjust.
Identities = 61/179 (34%), Positives = 103/179 (58%), Gaps = 5/179 (3%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
+P+++ GP G++ L +RL+ D+ +V HTTR+ R E G DYHFV+++ F+
Sbjct 19 KPVVVFGPSGVGKSTLLKRLLKDHGDKLGFSVSHTTRTPRAGEKDGIDYHFVTKEEFQKL 78
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
+A KF+E F N+YGTSI +++++ K +L + Q + ++ S + +F+AP
Sbjct 79 VAEEKFVEWAVFSGNMYGTSIMAIQELEAVNKKAILDIDLQGVLQVKASPIDAQYVFLAP 138
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTR---EMEQNNGHYFDTAIVNSDLDKAYQEL 655
PS E+L L G + L+ +E+ R E + G+ FD IVN D++KAY++L
Sbjct 139 PSIEQLEVRLRGRGTENESAILQR-LERARAEIEYSEKPGN-FDALIVNDDVEKAYKQL 195
>sp|Q9M682|GMK2_ARATH Guanylate kinase 2 OS=Arabidopsis thaliana
OX=3702 GN=GK-2 PE=2 SV=1
Length=389
Score = 113 bits (283), Expect = 8e-26, Method: Compositional matrix adjust.
Identities = 62/192 (32%), Positives = 97/192 (51%), Gaps = 1/192 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
N ++PI++ GP G+ L LM + F +V HTTR+ R E G YHF +
Sbjct 134 GNAEKPIVISGPSGVGKGTLISMLMKEFPSMFGFSVSHTTRAPRCMEKNGVHYHFTDKTV 193
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
E +I GKF+E NLYGTSI+SV V +SGK C+L + Q ++++ S L I
Sbjct 194 MEKEIKDGKFLEFASVHGNLYGTSIESVEVVTDSGKRCILDIDVQGARSVKASSLDAIFI 253
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQN-NGHYFDTAIVNSDLDKAYQE 654
F+ PPS + L L G + + + + E++ + F+ + N +L++ Y+
Sbjct 254 FVCPPSMKELEDRLRARGTETEEQIQKRLRNADAEIKAGKSSGIFEHKLYNDNLEECYKT 313
Query 655 LLRLINKLDTEP 666
L L+ D P
Sbjct 314 LKNLLGINDLAP 325
>sp|Q54XF2|KGUA_DICDI Guanylate kinase OS=Dictyostelium discoideum
OX=44689 GN=guk1 PE=3 SV=1
Length=202
Score = 104 bits (260), Expect = 2e-24, Method: Composition-based stats.
Identities = 61/182 (34%), Positives = 97/182 (53%), Gaps = 3/182 (2%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
PII+ GP G+ L +L + + F V HTTR R+ E+ G YHF I
Sbjct 11 PIIITGPSGVGKGTLIDKLRKEYEGSFGHIVSHTTRKPREGEINGVHYHFTDIPTMTEGI 70
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
G FIEH N YGTS +++ V + KIC+L + Q ++++ +++ IFI+PP
Sbjct 71 KNGDFIEHANVHGNFYGTSKKALKDVSDKNKICILDIDVQGCESVKKANIPCKFIFISPP 130
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTRE--MEQNNGHYFDTAIVNSDLDKAYQELLRL 658
+ E L+ L G + E L++ +E ++ + ++ +FD IVN+ LD AY EL +
Sbjct 131 TFETLQERLIGRGTENE-ETLKKRLETAKKEMVYRDIPGFFDHVIVNNVLDVAYGELKSI 189
Query 659 IN 660
I+
Sbjct 190 IS 191
>sp|Q72DM9|KGUA_DESVH Guanylate kinase OS=Desulfovibrio vulgaris
(strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 /
Hildenborough) OX=882 GN=gmk PE=3 SV=1
Length=207
Score = 104 bits (260), Expect = 3e-24, Method: Composition-based stats.
Identities = 61/174 (35%), Positives = 92/174 (53%), Gaps = 3/174 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++L P G+ L +RL+ E RFA +V +TTR R+ EV G+DYHFV+ +AF
Sbjct 10 LVLCAPSGTGKTTLTRRLLT-EFPRFAFSVSYTTRKPRNGEVDGKDYHFVTVEAFLRLRD 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
AG F E E N YGT + + +++ G+ L + Q + LR S + +FI PPS
Sbjct 69 AGFFAEWAEVHGNFYGTPLKATLDLLDEGRDVLFDIDVQGARQLRASLQRGRYVFIMPPS 128
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
++ L L G + + R + +E+ + FD IVN DL++AY EL
Sbjct 129 RDELEHRLRARGTDDEETIARRLANAAKELRE--ARRFDAWIVNDDLERAYDEL 180
>sp|Q1WUB5|KGUA_LIGS1 Guanylate kinase OS=Ligilactobacillus salivarius
(strain UCC118) OX=362948 GN=gmk PE=3 SV=1
Length=205
Score = 103 bits (256), Expect = 8e-24, Method: Compositional matrix adjust.
Identities = 57/187 (30%), Positives = 104/187 (56%), Gaps = 8/187 (4%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A R I+L GP G+ +R+ + ++ ++F +V TTR R EV G+DY+FVS++
Sbjct 2 AKRGMLIVLSGPSGVGKGTVRKEIFSQPGNKFHYSVSMTTREMRPGEVNGKDYYFVSKEE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE +IAAG+ +E+ ++ N YGT + V ++++SGK L + + +R I
Sbjct 62 FEQEIAAGQMLEYAQYVDNYYGTPLKYVNEMLDSGKDVFLEIEVKGAMQVREKAPDGLFI 121
Query 596 FIAPPSQERLRALLAKEGK---NPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAY 652
F+ PP LR + G + + +++ +++ EM QN +D A+VN +++KA
Sbjct 122 FLTPPDLMELRQRIINRGTDDIDTINKRMKKAVDEI-EMMQN----YDYAVVNDEVEKAA 176
Query 653 QELLRLI 659
+++ +I
Sbjct 177 EKIKTII 183
>sp|Q30XT1|KGUA_OLEA2 Guanylate kinase OS=Oleidesulfovibrio alaskensis
(strain ATCC BAA-1058 / DSM 17464 / G20) OX=207559
GN=gmk PE=3 SV=1
Length=206
Score = 101 bits (252), Expect = 3e-23, Method: Composition-based stats.
Identities = 61/174 (35%), Positives = 90/174 (52%), Gaps = 3/174 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++L P G+ L +RL+ +E RFA +V +TTR R E GR+Y+FV + F
Sbjct 10 LVLCAPSGTGKTTLTRRLL-EEFPRFAFSVSYTTRQPRAGEEHGREYNFVDEETFIRLRD 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G F E E N YGT ++ RQ++ G+ L + Q LR S + +FI PPS
Sbjct 69 EGFFAEWAEVHGNFYGTPLEDTRQLLARGRDVLFDIDVQGAAQLRGSLKQGCYVFILPPS 128
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
L L G +P+ R + RE++Q H+F+ IVN +L++AY EL
Sbjct 129 GAELERRLRARGTDPEDTIRRRLANARRELQQ--AHWFNAWIVNDNLEQAYDEL 180
>sp|Q3MD38|KGUA_TRIV2 Guanylate kinase OS=Trichormus variabilis
(strain ATCC 29413 / PCC 7937) OX=240292 GN=gmk PE=3 SV=1
Length=199
Score = 99.8 bits (247), Expect = 1e-22, Method: Compositional matrix adjust.
Identities = 61/194 (31%), Positives = 100/194 (52%), Gaps = 3/194 (2%)
Query 462 EILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQ 521
++L+ + + + + + I+L GP G+ L + L+ + + + S V TTR+ R
Sbjct 3 QVLSIQNCATTKENPSSGKLIVLTGPSGVGKGTLMRSLLQRHPELYYS-VSATTRAPRPG 61
Query 522 EVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS 581
EV G Y+F+SR FE +A G+F+E EF N YGT ++V I SGK+ +L +
Sbjct 62 EVNGESYYFISRNKFEELLAQGEFLESAEFAGNYYGTPREAVLNQIQSGKLVVLEIELAG 121
Query 582 LKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDT 641
+ +R S + IFI PPS E L + G++ + R + T E++ + FD
Sbjct 122 ARQIRASFPEALSIFILPPSFEELEKRIRGRGQDSEEAIARRLQRATEEIQAAD--EFDI 179
Query 642 AIVNSDLDKAYQEL 655
IVN D + A Q +
Sbjct 180 QIVNDDFEAALQAI 193
>sp|Q8Z0I7|KGUA_NOSS1 Guanylate kinase OS=Nostoc sp. (strain PCC
7120 / SAG 25.82 / UTEX 2576) OX=103690 GN=gmk PE=3 SV=1
Length=199
Score = 98.6 bits (244), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 62/174 (36%), Positives = 91/174 (52%), Gaps = 3/174 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
IIL GP G+ L + L+ + + + S V TTR R EV G Y+FVSR FE IA
Sbjct 23 IILTGPSGVGKGTLMRSLLQRHPELYYS-VSATTRPPRPGEVNGESYYFVSRSKFEELIA 81
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+F+E EF N YGT ++V + SGK+ +L + + +R S + IFI PPS
Sbjct 82 QGEFLESAEFAGNYYGTPREAVLNQVQSGKLVVLEIELAGARQIRTSFPEALSIFILPPS 141
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
E L + G++ + E + +++ +E E FD IVN D + A Q +
Sbjct 142 FEELENRIRGRGQDSE-EAIARRLQRAKE-EIQAADEFDIQIVNDDFEAALQAI 193
>sp|Q8NX22|KGUA_STAAW Guanylate kinase OS=Staphylococcus aureus
(strain MW2) OX=196620 GN=gmk PE=3 SV=1
Length=207
Score = 99.0 bits (245), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 56/170 (33%), Positives = 85/170 (50%), Gaps = 2/170 (1%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +R+R+ + ++ TTR R+ EV G DY F +R AFEA I
Sbjct 9 IVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFFKTRDAFEALIK 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+FIE+ E+ N YGT + V+ ++ G L + + K +R IF+APPS
Sbjct 69 DDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDALFIFLAPPS 128
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
E LR L G + I E +E+E N +D +VN +++ A
Sbjct 129 LEHLRERLVGRGTESDEKIQSRINEARKEVEMMN--LYDYVVVNDEVELA 176
>sp|Q6GA04|KGUA_STAAS Guanylate kinase OS=Staphylococcus aureus
(strain MSSA476) OX=282459 GN=gmk PE=3 SV=1
Length=207
Score = 99.0 bits (245), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 56/170 (33%), Positives = 85/170 (50%), Gaps = 2/170 (1%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +R+R+ + ++ TTR R+ EV G DY F +R AFEA I
Sbjct 9 IVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFFKTRDAFEALIK 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+FIE+ E+ N YGT + V+ ++ G L + + K +R IF+APPS
Sbjct 69 DDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDALFIFLAPPS 128
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
E LR L G + I E +E+E N +D +VN +++ A
Sbjct 129 LEHLRERLVGRGTESDEKIQSRINEARKEVEMMN--LYDYVVVNDEVELA 176
>sp|Q5HGM3|KGUA_STAAC Guanylate kinase OS=Staphylococcus aureus
(strain COL) OX=93062 GN=gmk PE=1 SV=1
Length=207
Score = 99.0 bits (245), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 56/170 (33%), Positives = 85/170 (50%), Gaps = 2/170 (1%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +R+R+ + ++ TTR R+ EV G DY F +R AFEA I
Sbjct 9 IVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFFKTRDAFEALIK 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+FIE+ E+ N YGT + V+ ++ G L + + K +R IF+APPS
Sbjct 69 DDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDALFIFLAPPS 128
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
E LR L G + I E +E+E N +D +VN +++ A
Sbjct 129 LEHLRERLVGRGTESDEKIQSRINEARKEVEMMN--LYDYVVVNDEVELA 176
>sp|Q2G1U0|KGUA_STAA8 Guanylate kinase OS=Staphylococcus aureus
(strain NCTC 8325 / PS 47) OX=93061 GN=gmk PE=3 SV=1
Length=207
Score = 99.0 bits (245), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 56/170 (33%), Positives = 85/170 (50%), Gaps = 2/170 (1%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +R+R+ + ++ TTR R+ EV G DY F +R AFEA I
Sbjct 9 IVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFFKTRDAFEALIK 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+FIE+ E+ N YGT + V+ ++ G L + + K +R IF+APPS
Sbjct 69 DDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDALFIFLAPPS 128
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
E LR L G + I E +E+E N +D +VN +++ A
Sbjct 129 LEHLRERLVGRGTESDEKIQSRINEARKEVEMMN--LYDYVVVNDEVELA 176
>sp|Q2FHM9|KGUA_STAA3 Guanylate kinase OS=Staphylococcus aureus
(strain USA300) OX=367830 GN=gmk PE=3 SV=1
Length=207
Score = 99.0 bits (245), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 56/170 (33%), Positives = 85/170 (50%), Gaps = 2/170 (1%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +R+R+ + ++ TTR R+ EV G DY F +R AFEA I
Sbjct 9 IVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFFKTRDAFEALIK 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+FIE+ E+ N YGT + V+ ++ G L + + K +R IF+APPS
Sbjct 69 DDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDALFIFLAPPS 128
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
E LR L G + I E +E+E N +D +VN +++ A
Sbjct 129 LEHLRERLVGRGTESDEKIQSRINEARKEVEMMN--LYDYVVVNDEVELA 176
>sp|Q82ZD5|KGUA_ENTFA Guanylate kinase OS=Enterococcus faecalis
(strain ATCC 700802 / V583) OX=226185 GN=gmk PE=3 SV=1
Length=204
Score = 98.6 bits (244), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 57/184 (31%), Positives = 97/184 (53%), Gaps = 2/184 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+L GP G+ +R+ + + E++ F ++ TTR +R+ EV G DY+F SR+
Sbjct 2 SERGLLIVLSGPSGVGKGTVRKAIFDSEENDFQYSISMTTRKQREGEVDGVDYYFRSREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FEA I AG+ +E+ E+ N YGT + V Q ++ GK L + Q K +++ I
Sbjct 62 FEAMIEAGEMLEYAEYVGNYYGTPLTYVNQTLDEGKDVFLEIEVQGAKQVKDKVPDGVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP L++ + G + + + E + RE E +D A+VN ++ A Q +
Sbjct 122 FLTPPDLAELKSRIIGRGTD-EMSVIEERMAVARE-EIEMMALYDYAVVNDEVPLAVQRI 179
Query 656 LRLI 659
+I
Sbjct 180 KDII 183
>sp|Q8DMQ7|KGUA_THEVB Guanylate kinase OS=Thermosynechococcus
vestitus (strain NIES-2133 / IAM M-273 / BP-1) OX=197221 GN=gmk
PE=3 SV=1
Length=191
Score = 97.4 bits (241), Expect = 5e-22, Method: Compositional matrix adjust.
Identities = 61/170 (36%), Positives = 89/170 (52%), Gaps = 3/170 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I++ GP G+ L ++L + + A +V TTR R EVAG DY+FVS + F+A IA
Sbjct 12 IVITGPSGVGKGTLLRQLRQRHPE-LALSVSATTRPPRPTEVAGVDYYFVSVEEFKAMIA 70
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
AG+ +E EF + YGT + Q+I GK +L + Q + +R S + IFI PPS
Sbjct 71 AGQLLEWAEFAGHYYGTPRQPLVQLIAQGKTVILEIELQGARQVRQSYPQARHIFILPPS 130
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
L L G++ + R + + E E FD IVN DL+K+
Sbjct 131 LAELEHRLRSRGQDSEEAIARRLAQA--ETEIAAAPEFDVQIVNDDLEKS 178
>sp|P99176|KGUA_STAAN Guanylate kinase OS=Staphylococcus aureus
(strain N315) OX=158879 GN=gmk PE=1 SV=1
Length=207
Score = 97.8 bits (242), Expect = 6e-22, Method: Compositional matrix adjust.
Identities = 55/170 (32%), Positives = 85/170 (50%), Gaps = 2/170 (1%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +R+R+ + ++ TTR R+ EV G DY F +R AFEA I
Sbjct 9 IVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFFKTRDAFEALIK 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+FIE+ E+ N YGT + V+ ++ G L + + K +R IF+APPS
Sbjct 69 DDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDALFIFLAPPS 128
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
+ LR L G + I E +E+E N +D +VN +++ A
Sbjct 129 LDHLRERLVGRGTESNEKIQSRINEARKEVEMMN--LYDYVVVNDEVELA 176
>sp|P65219|KGUA_STAAM Guanylate kinase OS=Staphylococcus aureus
(strain Mu50 / ATCC 700699) OX=158878 GN=gmk PE=3 SV=1
Length=207
Score = 97.8 bits (242), Expect = 6e-22, Method: Compositional matrix adjust.
Identities = 55/170 (32%), Positives = 85/170 (50%), Gaps = 2/170 (1%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +R+R+ + ++ TTR R+ EV G DY F +R AFEA I
Sbjct 9 IVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFFKTRDAFEALIK 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+FIE+ E+ N YGT + V+ ++ G L + + K +R IF+APPS
Sbjct 69 DDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDALFIFLAPPS 128
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
+ LR L G + I E +E+E N +D +VN +++ A
Sbjct 129 LDHLRERLVGRGTESNEKIQSRINEARKEVEMMN--LYDYVVVNDEVELA 176
>sp|Q6GHM6|KGUA_STAAR Guanylate kinase OS=Staphylococcus aureus
(strain MRSA252) OX=282458 GN=gmk PE=3 SV=1
Length=207
Score = 97.8 bits (242), Expect = 7e-22, Method: Compositional matrix adjust.
Identities = 55/170 (32%), Positives = 85/170 (50%), Gaps = 2/170 (1%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +R+R+ + ++ TTR R+ EV G DY F +R AFEA I
Sbjct 9 IVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFFKTRDAFEALIK 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+FIE+ E+ N YGT + V+ ++ G L + + K +R IF+APPS
Sbjct 69 DDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDALFIFLAPPS 128
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
+ LR L G + I E +E+E N +D +VN +++ A
Sbjct 129 LDHLRERLVGRGTESDEKIQSRINEARKEVEMMN--LYDYVVVNDEVELA 176
>sp|Q2YXF9|KGUA_STAAB Guanylate kinase OS=Staphylococcus aureus
(strain bovine RF122 / ET3-1) OX=273036 GN=gmk PE=3 SV=1
Length=207
Score = 97.8 bits (242), Expect = 7e-22, Method: Compositional matrix adjust.
Identities = 55/170 (32%), Positives = 85/170 (50%), Gaps = 2/170 (1%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +R+R+ + ++ TTR R+ EV G DY F +R AFEA I
Sbjct 9 IVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFFKTRDAFEALIK 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+FIE+ E+ N YGT + V+ ++ G L + + K +R IF+APPS
Sbjct 69 DDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDALFIFLAPPS 128
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
+ LR L G + I E +E+E N +D +VN +++ A
Sbjct 129 LDHLRERLVGRGTESDEKIQSRINEARKEVEMMN--LYDYVVVNDEVELA 176
>sp|Q38XU0|KGUA_LATSS Guanylate kinase OS=Latilactobacillus sakei
subsp. sakei (strain 23K) OX=314315 GN=gmk PE=3 SV=1
Length=203
Score = 97.1 bits (240), Expect = 9e-22, Method: Compositional matrix adjust.
Identities = 58/187 (31%), Positives = 95/187 (51%), Gaps = 8/187 (4%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+NR I+L GP G+ +RQ ++ E F +V TTR R E G DY+FVS++
Sbjct 2 SNRGMLIVLSGPSGVGKGTVRQAMLEDEFRDFHYSVSMTTRKPRPGEQDGVDYYFVSKEE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE +IA +E+ ++ N YGT + V Q + SG+ LL + Q +R I
Sbjct 62 FEQEIANDGMLEYAQYVDNYYGTPMKYVNQTLESGRDVLLEIEVQGAMQVREKCPDGVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKP---EELREIIEKTREMEQNNGHYFDTAIVNSDLDKAY 652
F+ PP LR + K G + + + +++ ++ R ME +D A+VN ++ A
Sbjct 122 FLTPPDLLELRNRIQKRGTDDQATIDKRMQKAADEIRMMEN-----YDYAVVNDEIPNAV 176
Query 653 QELLRLI 659
Q + ++I
Sbjct 177 QRIEKII 183
>sp|Q1GH67|KGUA_RUEST Guanylate kinase OS=Ruegeria sp. (strain
TM1040) OX=292414 GN=gmk PE=3 SV=1
Length=217
Score = 97.4 bits (241), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 64/193 (33%), Positives = 100/193 (52%), Gaps = 6/193 (3%)
Query 471 LYHQPANRKRP-IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYH 529
+ H A R+ IIL P G++ L +RL + D + +V TTR R EV G+DYH
Sbjct 1 MAHSKAQRRGLLIILSSPSGAGKSTLAKRLRAWDSD-ISFSVSATTRKPRPGEVDGQDYH 59
Query 530 FVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD 589
FV+ ++F+ D+A G +EH N YG+ V+ IN G+ L + Q + + NSD
Sbjct 60 FVTVESFKQDVANGDMLEHAHVFGNFYGSPKGPVQTAINEGRDVLFDIDWQGAQQITNSD 119
Query 590 LKPYI--IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD 647
L + IF+ PPS LR L G++ E + ++K+ + + G Y D ++N D
Sbjct 120 LGKHTLSIFLLPPSITELRRRLESRGQD-DAETISRRMQKSWDEISHWGSY-DHVLINED 177
Query 648 LDKAYQELLRLIN 660
LD+ + L +I
Sbjct 178 LDETEEALKTIIT 190
>sp|O34328|KGUA_BACSU Guanylate kinase OS=Bacillus subtilis (strain
168) OX=224308 GN=gmk PE=3 SV=2
Length=204
Score = 96.7 bits (239), Expect = 1e-21, Method: Compositional matrix adjust.
Identities = 49/132 (37%), Positives = 71/132 (54%), Gaps = 0/132 (0%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +RQ + ++E +F ++ TTRS R+ EV G DY F +R FE IA
Sbjct 8 IVLSGPSGVGKGTVRQAIFSQEDTKFEYSISVTTRSPREGEVNGVDYFFKTRDEFEQMIA 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
K +E E+ N YGT +D V Q + GK L + Q +RN+ + IF+APPS
Sbjct 68 DNKLLEWAEYVGNYYGTPVDYVEQTLQDGKDVFLEIEVQGALQVRNAFPEGLFIFLAPPS 127
Query 602 QERLRALLAKEG 613
L+ + G
Sbjct 128 LSELKNRIVTRG 139
>sp|Q3SLI4|KGUA_THIDA Guanylate kinase OS=Thiobacillus denitrificans
(strain ATCC 25259) OX=292415 GN=gmk PE=3 SV=1
Length=209
Score = 96.7 bits (239), Expect = 2e-21, Method: Composition-based stats.
Identities = 66/196 (34%), Positives = 97/196 (49%), Gaps = 9/196 (5%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
PA+ I+ P G+ L + L+ K +V HTTR+ R E GRDYHFV+R
Sbjct 4 PASPGVLYIVSAPSGAGKTSLVKALL-KSDPAIRLSVSHTTRAPRPGESDGRDYHFVARD 62
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
FE +A G+F+EH E N YGTS + Q +++G+ LL + Q + ++ +
Sbjct 63 TFEKMLADGEFLEHAEVYGNFYGTSRGRIGQELDAGRDLLLEIDWQGAEQVKRHFPQSTS 122
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEK---TREMEQNNGHYFDTAIVNSDLDKA 651
IFI PP+ LR L G++ EIIE+ + + FD IVN D D A
Sbjct 123 IFILPPTFSALRTRLTGRGQDSP-----EIIERRLAAAAHDVAHAEAFDYIIVNDDFDHA 177
Query 652 YQELLRLINKLDTEPQ 667
Q+L+ + + E Q
Sbjct 178 LQDLVAITRSIRLEAQ 193
>sp|Q88C87|KGUA_PSEPK Guanylate kinase OS=Pseudomonas putida (strain
ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
OX=160488 GN=gmk PE=3 SV=1
Length=206
Score = 95.9 bits (237), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 61/175 (35%), Positives = 90/175 (51%), Gaps = 7/175 (4%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I+ P G+ L L K+ + +V HTTR+ R E G +YHFV + F+A IA
Sbjct 10 IVSAPSGAGKTSLVTAL-TKDDQQIRVSVSHTTRAMRPGEQHGVNYHFVVHEEFKALIAQ 68
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
G F+EH E N YGTS +++Q ++ G +L + Q + +R + +FI PPSQ
Sbjct 69 GDFLEHAEVFGNFYGTSRSALQQTLDQGYDLILEIDWQGAQQVRKLMPQALSVFILPPSQ 128
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQEL 655
E LR L +G+ EE+ I + +E HY +D I+N D D A +L
Sbjct 129 EALRHRL--DGRGQDSEEI--IAGRMKEAVSEMVHYDEYDYVIINDDFDTALADL 179
>sp|P60549|KGUA_BDEBA Guanylate kinase OS=Bdellovibrio bacteriovorus
(strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100)
OX=264462 GN=gmk PE=3 SV=1
Length=185
Score = 95.1 bits (235), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 59/186 (32%), Positives = 87/186 (47%), Gaps = 5/186 (3%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ R II+ P G++ +R+ +E R V TTRS R E G Y+F+ FE
Sbjct 2 KTRMIIVAAPSGAGKSSFVERI-TREDSRLVDIVTFTTRSIRQGETPGLQYNFIDHADFE 60
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I G F+E + N YGTS S+ N GK ++ + Q + T ++ +FI
Sbjct 61 QKIKEGFFVEWAKVHTNFYGTSYSSLETAWNQGKTAIMDIDIQGVATFKSKFPDAKTVFI 120
Query 598 APPSQERLRALLAK-EGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
PPS + LR + K +GK P E+R E E FD IVN +K+Y E
Sbjct 121 HPPSIDELRRRIEKRDGKVPADIEVR---MANAEKEIREASKFDYQIVNDVFEKSYGEFK 177
Query 657 RLINKL 662
+++ L
Sbjct 178 KIVEDL 183
>sp|Q5F775|KGUA_NEIG1 Guanylate kinase OS=Neisseria gonorrhoeae
(strain ATCC 700825 / FA 1090) OX=242231 GN=gmk PE=3 SV=1
Length=205
Score = 94.7 bits (234), Expect = 7e-21, Method: Composition-based stats.
Identities = 64/186 (34%), Positives = 96/186 (52%), Gaps = 4/186 (2%)
Query 476 ANRKRPIILI-GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
A RK I +I G+ L RL+ + +V HTTR R+ E G YHFVS++
Sbjct 3 AYRKGNIFIISAASGTGKTTLVSRLL-ANHNGLRVSVSHTTRPPREGEANGVHYHFVSKE 61
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
FE+ IA F+E+ + N YGTS + V + +G +L + Q +RN+ +
Sbjct 62 EFESLIAQEAFLEYADVFGNYYGTSTEGVNALAAAGYDVILEIDVQGAAQVRNALPEAVG 121
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFI PPS + L A L G + + R + + E+EQ+ FD +VN DL+KA +
Sbjct 122 IFILPPSFDVLAARLKGRGTDSREVIQRRLSKARHEIEQSV--LFDFVVVNDDLEKAEGD 179
Query 655 LLRLIN 660
LL ++N
Sbjct 180 LLHIVN 185
>sp|Q01230|A57_VACCW Guanylate kinase homolog OS=Vaccinia virus
(strain Western Reserve) OX=10254 GN=VACWR182 PE=3 SV=3
Length=151
Score = 92.8 bits (229), Expect = 7e-21, Method: Composition-based stats.
Identities = 50/139 (36%), Positives = 78/139 (56%), Gaps = 1/139 (1%)
Query 522 EVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS 581
E G DYH+V+R+A IAAG F+EH EF N+YGTS +V + +IC++ L
Sbjct 2 EREGVDYHYVNREAIWKGIAAGNFLEHTEFLGNIYGTSKTAVNTAAINNRICVMDLNIDG 61
Query 582 LKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPE-ELREIIEKTREMEQNNGHYFD 640
+++L+N+ L PY ++I P S + + L E R I+ KT E N FD
Sbjct 62 VRSLKNTYLMPYSVYIRPTSLKMVETKLRCRNTEANDEIHRRVILAKTDMDEANEAGLFD 121
Query 641 TAIVNSDLDKAYQELLRLI 659
T I+ D++ AY +L++++
Sbjct 122 TIIIEDDVNLAYSKLIQIL 140
>sp|Q5SI18|KGUA_THET8 Guanylate kinase OS=Thermus thermophilus
(strain ATCC 27634 / DSM 579 / HB8) OX=300852 GN=gmk PE=3 SV=1
Length=223
Score = 95.1 bits (235), Expect = 8e-21, Method: Composition-based stats.
Identities = 57/182 (31%), Positives = 98/182 (54%), Gaps = 4/182 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R R ++ G G+ +R +++ E+ R ++ TTR R EV G DY+FV R FE
Sbjct 5 RGRLFVMTGASGVGKGTVRAKVL--ERTRLFYSISMTTRPPRPGEVDGVDYYFVDRPTFE 62
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
A + F+E+ E+ +LYGT V + ++ G+ LL + Q ++ + + +IF+
Sbjct 63 ALVREDGFLEYAEYVGHLYGTPRAPVERALSRGEDVLLEIEVQGALQVKRAVPEAVLIFL 122
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS L+ L GK+ PE++++ +E+ E E N H FD +VN L++A + L
Sbjct 123 LPPSLSELKRRLVYRGKD-SPEKIQKRLEQA-EWEIRNAHLFDYVVVNDVLEEAVADFLA 180
Query 658 LI 659
++
Sbjct 181 IL 182
>sp|Q72ID5|KGUA_THET2 Guanylate kinase OS=Thermus thermophilus
(strain ATCC BAA-163 / DSM 7039 / HB27) OX=262724 GN=gmk PE=3
SV=1
Length=220
Score = 94.7 bits (234), Expect = 9e-21, Method: Composition-based stats.
Identities = 57/182 (31%), Positives = 98/182 (54%), Gaps = 4/182 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R R ++ G G+ +R +++ E+ R ++ TTR R EV G DY+FV R FE
Sbjct 2 RGRLFVMTGASGVGKGTVRAKVL--ERTRLFYSISMTTRPPRPGEVDGVDYYFVDRPTFE 59
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
A + F+E+ E+ +LYGT V + ++ G+ LL + Q ++ + + +IF+
Sbjct 60 ALVREDGFLEYAEYVGHLYGTPRAPVERALSRGEDVLLEIEVQGALQVKRAVPEAVLIFL 119
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS L+ L GK+ PE++++ +E+ E E N H FD +VN L++A + L
Sbjct 120 LPPSLSELKRRLVYRGKD-SPEKIQKRLEQA-EWEIRNAHLFDYVVVNDVLEEAVADFLA 177
Query 658 LI 659
++
Sbjct 178 IL 179
>sp|Q0TPK6|KGUA_CLOP1 Guanylate kinase OS=Clostridium perfringens
(strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC
8237 / Type A) OX=195103 GN=gmk PE=3 SV=1
Length=216
Score = 94.0 bits (232), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 59/179 (33%), Positives = 94/179 (53%), Gaps = 3/179 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
NR I++ GP G+ + + L+ K D F S V TTR+ R EV G +YHF++++ F
Sbjct 9 NRGVLIVISGPSGAGKGTICKALLEKHDDIFIS-VSATTRNPRVGEVDGVNYHFLTKEEF 67
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ IA F+EH E N YGT SV ++++ GK +L + Q ++ IF
Sbjct 68 KQRIAEDDFLEHAEVYGNYYGTPKSSVEKMLDEGKNVILEIDIQGALKVKEKATDGVFIF 127
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
I PPS E L+ + K G + PE L K+ E N ++ A+VN +++ A +++
Sbjct 128 ILPPSMEELKQRIIKRG-SETPESLMTRF-KSAYKEINYVSKYNYAVVNDNVEDAVKKI 184
>sp|P21074|A57_VACCC Guanylate kinase homolog OS=Vaccinia virus
(strain Copenhagen) OX=10249 GN=A57R PE=3 SV=3
Length=151
Score = 91.7 bits (226), Expect = 2e-20, Method: Composition-based stats.
Identities = 49/139 (35%), Positives = 77/139 (55%), Gaps = 1/139 (1%)
Query 522 EVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS 581
E G DYH+V+R+A IAAG F+EH EF N+YGTS +V + +IC++ L
Sbjct 2 EREGVDYHYVNREAIWKGIAAGNFLEHTEFLGNIYGTSKTAVNTAAINNRICVMDLNIDG 61
Query 582 LKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPE-ELREIIEKTREMEQNNGHYFD 640
+++ +N+ L PY ++I P S + + L E R I+ KT E N FD
Sbjct 62 VRSFKNTYLMPYSVYIRPTSLKMVETKLRCRNTEANDEIHRRVILAKTDMDEANEAGLFD 121
Query 641 TAIVNSDLDKAYQELLRLI 659
T I+ D++ AY +L++++
Sbjct 122 TIIIEDDVNLAYSKLIQIL 140
>sp|Q0SS73|KGUA_CLOPS Guanylate kinase OS=Clostridium perfringens
(strain SM101 / Type A) OX=289380 GN=gmk PE=3 SV=1
Length=216
Score = 93.6 bits (231), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 59/179 (33%), Positives = 94/179 (53%), Gaps = 3/179 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
NR I++ GP G+ + + L+ K D F S V TTR+ R EV G +YHF++++ F
Sbjct 9 NRGVLIVISGPSGAGKGTICKALLEKHDDIFIS-VSATTRNPRVGEVDGVNYHFLTKEEF 67
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ IA F+EH E N YGT SV ++++ GK +L + Q ++ IF
Sbjct 68 KQRIAEDDFLEHAEVYGNYYGTPKSSVEKMLDEGKNVILEIDIQGALKVKEKATDGVFIF 127
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
I PPS E L+ + K G + PE L K+ E N ++ A+VN +++ A +++
Sbjct 128 ILPPSMEELKQRIIKRG-SETPESLMTRF-KSAYKEINYVSKYNYAVVNDNVEDAVKKI 184
>sp|Q49WZ1|KGUA_STAS1 Guanylate kinase OS=Staphylococcus saprophyticus
subsp. saprophyticus (strain ATCC 15305 / DSM 20229
/ NCIMB 8711 / NCTC 7292 / S-41) OX=342451 GN=gmk PE=3 SV=1
Length=207
Score = 93.2 bits (230), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 51/178 (29%), Positives = 88/178 (49%), Gaps = 2/178 (1%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +R+++ + + ++ TTR +R EV G DY F ++ FE I
Sbjct 9 IVLSGPSGVGKGTVRKKIFDDPSTSYKYSISMTTRDKRQGEVDGVDYFFKAKSEFEELIK 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+FIE+ E+ N YGT + V+ ++ G L + + K +R IF+APPS
Sbjct 69 QDQFIEYAEYVGNYYGTPVQYVKDTMDRGYDVFLEIEVEGAKQVRKKFPDALFIFLAPPS 128
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
+ LR L G + + E +E+E N +D +VN +++ A Q + ++
Sbjct 129 LDHLRERLVGRGTESSEKIQSRVHEARKEVEMMN--LYDYVVVNDEVELAKQRIQSIV 184
>sp|Q8XJK8|KGUA_CLOPE Guanylate kinase OS=Clostridium perfringens
(strain 13 / Type A) OX=195102 GN=gmk PE=3 SV=3
Length=216
Score = 93.2 bits (230), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 58/179 (32%), Positives = 94/179 (53%), Gaps = 3/179 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
NR I++ GP G+ + + L+ K D F S + TTR+ R EV G +YHF++++ F
Sbjct 9 NRGVLIVISGPSGAGKGTICKALLEKHDDIFIS-ISATTRNPRVGEVDGVNYHFLTKEEF 67
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ IA F+EH E N YGT SV ++++ GK +L + Q ++ IF
Sbjct 68 KQRIAEDDFLEHAEVYGNYYGTPKSSVEKMLDEGKNVILEIDIQGALKVKEKATDGVFIF 127
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
I PPS E L+ + K G + PE L K+ E N ++ A+VN +++ A +++
Sbjct 128 ILPPSMEELKQRIIKRG-SETPESLMTRF-KSAYKEINYVSKYNYAVVNDNVEDAVKKI 184
>sp|Q166A7|KGUA_ROSDO Guanylate kinase OS=Roseobacter denitrificans
(strain ATCC 33942 / OCh 114) OX=375451 GN=gmk PE=3 SV=1
Length=211
Score = 92.0 bits (227), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 59/181 (33%), Positives = 92/181 (51%), Gaps = 5/181 (3%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
IIL P G++ L +RL + + D +V TTR+ R EV GR+YHFV AF++ ++
Sbjct 7 IILSSPSGAGKSTLARRLRDWDTD-IEFSVSATTRAARPGEVDGREYHFVDEAAFKSQVS 65
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI--IFIAP 599
G +EH N YG+ V++ IN+G+ L + Q + + NS L + IF+ P
Sbjct 66 NGGMLEHAHVFGNFYGSPSGPVQEAINAGRDVLFDIDWQGAQQITNSALSAHTLSIFLLP 125
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
PS LR L K ++ R ++K+ + + G Y D +VN DLD L ++
Sbjct 126 PSIRELRNRLEKRAQDDAATIARR-MDKSWDEISHWGSY-DYVLVNDDLDTTEAHLKTIV 183
Query 660 N 660
Sbjct 184 T 184
>sp|Q3AWM1|KGUA_SYNS9 Guanylate kinase OS=Synechococcus sp. (strain
CC9902) OX=316279 GN=gmk PE=3 SV=2
Length=187
Score = 91.3 bits (225), Expect = 7e-20, Method: Composition-based stats.
Identities = 59/180 (33%), Positives = 95/180 (53%), Gaps = 3/180 (2%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A+ R +L GP G+ L +RL+++ + + S V TTR R E G Y F R
Sbjct 2 AHNGRLTVLTGPSGVGKGTLVKRLLDQHPEIWLS-VSATTRQPRAGEEEGVSYFFHPRDT 60
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F+A +AAG +E EF N YGT D V + + +G+ LL + + + +R S + +
Sbjct 61 FDALVAAGGLLEWAEFASNCYGTPRDPVEEHLAAGRPVLLEIELEGARQVRTSFPDAFQV 120
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+APPS L + G + + + ++ + + RE E N + FD +VN DLD+A ++L
Sbjct 121 FLAPPSFAELERRIRGRGTDTE-DAIQRRLARARE-ELNAQNEFDAVVVNDDLDQALKQL 178
>sp|Q4L5R1|KGUA_STAHJ Guanylate kinase OS=Staphylococcus haemolyticus
(strain JCSC1435) OX=279808 GN=gmk PE=3 SV=1
Length=207
Score = 91.7 bits (226), Expect = 8e-20, Method: Compositional matrix adjust.
Identities = 51/178 (29%), Positives = 89/178 (50%), Gaps = 2/178 (1%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +R+ + + + +V TTR+ R+ EV G DY F +++ FEA I
Sbjct 9 IVLSGPSGVGKGTVRKEIFDDPTTSYKYSVSMTTRNMREGEVDGVDYFFKTKEEFEALIQ 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+FIE+ E+ N YGT + V+ + +G L + + K +R IF+APPS
Sbjct 69 EDQFIEYAEYVGNYYGTPVQYVKDTMAAGHDVFLEIEVEGAKQVRKKFPDALFIFLAPPS 128
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
+ L+ L G + + E +E+E N +D +VN ++ A + + ++
Sbjct 129 LDHLKERLVGRGTESDEKIQSRVNEARKEVEMMN--LYDYVVVNDEVHLAKERIQSIV 184
>sp|P65221|KGUA_STRA5 Guanylate kinase OS=Streptococcus agalactiae
serotype V (strain ATCC BAA-611 / 2603 V/R) OX=208435 GN=gmk
PE=3 SV=1
Length=209
Score = 91.7 bits (226), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 56/184 (30%), Positives = 91/184 (49%), Gaps = 2/184 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFDYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FEA I G+ +E+ E+ N YGT + V + ++ G L + Q +++ I
Sbjct 62 FEALIKEGQMLEYAEYVGNYYGTPLSYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP E L L G + PE + + IE+ +E E +D A+VN + A + +
Sbjct 122 FLTPPDLEELEERLVGRGTD-SPEVIAQRIERAKE-EIALMREYDYAVVNDQVSLAAERV 179
Query 656 LRLI 659
R+I
Sbjct 180 KRVI 183
>sp|P65220|KGUA_STRA3 Guanylate kinase OS=Streptococcus agalactiae
serotype III (strain NEM316) OX=211110 GN=gmk PE=3 SV=1
Length=209
Score = 91.7 bits (226), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 56/184 (30%), Positives = 91/184 (49%), Gaps = 2/184 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFDYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FEA I G+ +E+ E+ N YGT + V + ++ G L + Q +++ I
Sbjct 62 FEALIKEGQMLEYAEYVGNYYGTPLSYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP E L L G + PE + + IE+ +E E +D A+VN + A + +
Sbjct 122 FLTPPDLEELEERLVGRGTD-SPEVIAQRIERAKE-EIALMREYDYAVVNDQVSLAAERV 179
Query 656 LRLI 659
R+I
Sbjct 180 KRVI 183
>sp|Q3K368|KGUA_STRA1 Guanylate kinase OS=Streptococcus agalactiae
serotype Ia (strain ATCC 27591 / A909 / CDC SS700) OX=205921
GN=gmk PE=3 SV=1
Length=209
Score = 91.7 bits (226), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 56/184 (30%), Positives = 91/184 (49%), Gaps = 2/184 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFDYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FEA I G+ +E+ E+ N YGT + V + ++ G L + Q +++ I
Sbjct 62 FEALIKEGQMLEYAEYVGNYYGTPLSYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP E L L G + PE + + IE+ +E E +D A+VN + A + +
Sbjct 122 FLTPPDLEELEERLVGRGTD-SPEVIAQRIERAKE-EIALMREYDYAVVNDQVSLAAERV 179
Query 656 LRLI 659
R+I
Sbjct 180 KRVI 183
>sp|Q5LS25|KGUA_RUEPO Guanylate kinase OS=Ruegeria pomeroyi (strain
ATCC 700808 / DSM 15171 / DSS-3) OX=246200 GN=gmk PE=3
SV=1
Length=213
Score = 91.7 bits (226), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 57/181 (31%), Positives = 93/181 (51%), Gaps = 5/181 (3%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
IIL P G++ L +RLM+ + +V TTR+ R E GR+Y+F+S F+ +
Sbjct 9 IILSSPSGAGKSTLARRLMSWDPG-LKFSVSATTRAPRPGEEHGREYYFLSEDQFKGQVR 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI--IFIAP 599
G+ +EH N YG+ VR I +G+ L + Q +RNSDL + IFI P
Sbjct 68 RGEMLEHAHVFGNFYGSPAGPVRDTIEAGQDVLFDVDWQGEIQIRNSDLGKHALSIFILP 127
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
PS + LR L G++ R +++ E+ ++ Y+D ++N DLD + L ++
Sbjct 128 PSIKELRRRLESRGQDSAEVISRRMLKSWDEI--SHWGYYDYVLINDDLDATEERLKTIV 185
Query 660 N 660
+
Sbjct 186 S 186
>sp|Q1AVZ3|KGUA_RUBXD Guanylate kinase OS=Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129 / PRD-1) OX=266117 GN=gmk
PE=3 SV=1
Length=191
Score = 90.1 bits (222), Expect = 2e-19, Method: Composition-based stats.
Identities = 59/185 (32%), Positives = 96/185 (52%), Gaps = 3/185 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R R I++ GP G++ L + ++ + A +V TTR+ R EV GRDY F+SR+ FE
Sbjct 3 RGRLIVVSGPSGAGKSTLIRAALDAVP-QLAYSVSATTRAPRPGEVNGRDYIFLSREEFE 61
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I G+F+E E+ NLYGT V + + SG +L + Q + +R +IF+
Sbjct 62 RWIREGRFLEWAEYSGNLYGTPAHRVEEYLESGLSVILEIELQGARKVRRKRPDAVMIFV 121
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PS E R L EG+ + E+ + T E FD +VN D ++A +E++
Sbjct 122 RAPSLEETRRRL--EGRATESEDAVQRRLATAVEEVAARDEFDCEVVNDDYERAREEMIE 179
Query 658 LINKL 662
++ ++
Sbjct 180 IMRRI 184
>sp|Q9CEE3|KGUA_LACLA Guanylate kinase OS=Lactococcus lactis subsp.
lactis (strain IL1403) OX=272623 GN=gmk PE=3 SV=1
Length=205
Score = 90.1 bits (222), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 54/178 (30%), Positives = 89/178 (50%), Gaps = 3/178 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+ GP G+ +R ++ E + F +V TTR +R EV G+DY+F +R FE I
Sbjct 8 IVFSGPSGVGKGTVRAKIFESENN-FEYSVSMTTRKQRPGEVDGKDYYFRTRDEFEEMIR 66
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+ +E+ E+ N YGT + V Q ++ GK L + Q ++ +F+ PP
Sbjct 67 NGQMLEYAEYVGNYYGTPLTYVNQTLDEGKDVFLEIEVQGALQVKEKVPDGVFVFLTPPD 126
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
E LR L G + E + +EK +E + Y D A+VN ++ A + + ++I
Sbjct 127 LEELRGRLVGRGTDS-AEVIASRLEKAKEEIRLMSEY-DYAVVNDKVELAAERVKKII 182
>sp|Q3B204|KGUA_CHLL3 Guanylate kinase OS=Chlorobium luteolum
(strain DSM 273 / BCRC 81028 / 2530) OX=319225 GN=gmk PE=3 SV=1
Length=197
Score = 89.7 bits (221), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 62/194 (32%), Positives = 101/194 (52%), Gaps = 14/194 (7%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFAS---AVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R ++ P G++ + +R++ +RF S +V TTR R+ EV G +YHF+S++ F
Sbjct 10 RLVVFSAPSGTGKSTIARRVL----ERFPSMRFSVSATTRPMREGEVDGVNYHFLSKEDF 65
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKP---Y 593
E++I G FIEH F N YGT + R+ + G LL L + L+ L P
Sbjct 66 ESEIRNGGFIEHEFFFGNHYGTLLQKTREAMAQGTDLLLDLDVKGAMNLKK--LFPDSSL 123
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
++F+APPS + L+ L K+ E L+ +E+ R +E FDT I+N L+ A +
Sbjct 124 LVFLAPPSMDVLKERLQSR-KSEDEESLKLRLERAR-LELGFADRFDTVIINDTLEDAVE 181
Query 654 ELLRLINKLDTEPQ 667
++ I+ + Q
Sbjct 182 AVILAISNFLSTKQ 195
>sp|Q2YD10|KGUA_NITMU Guanylate kinase OS=Nitrosospira multiformis
(strain ATCC 25196 / NCIMB 11849 / C 71) OX=323848 GN=gmk
PE=3 SV=1
Length=210
Score = 90.1 bits (222), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 60/189 (32%), Positives = 96/189 (51%), Gaps = 5/189 (3%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I+ P G+ L + L+ D + ++ +T+R R +E+ GRDYHFV+RQ FE +
Sbjct 10 IISAPSGAGKTSLVKALLQTGID-LSLSISYTSRQPRPEEMDGRDYHFVTRQVFEQKLQE 68
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
+F+E E N YGTS + + + SG+ LL + +Q + +R IF+ PPS
Sbjct 69 DEFLESAELYGNFYGTSKKWINETMTSGRDILLEIDSQGARQVRAVFPVAVGIFVLPPSL 128
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN-- 660
E L L + ++ E + + RE + G Y + I+N LD+A Q+L +I
Sbjct 129 EVLEMRLRQRAQD-SLEAISRRLAAAREELSHAGEY-NYIIINDKLDRALQDLKCIIQAE 186
Query 661 KLDTEPQWV 669
+L T Q V
Sbjct 187 RLKTAKQLV 195
>sp|Q7U570|KGUA_PARMW Guanylate kinase OS=Parasynechococcus marenigrum
(strain WH8102) OX=84588 GN=gmk PE=3 SV=1
Length=182
Score = 89.4 bits (220), Expect = 3e-19, Method: Composition-based stats.
Identities = 58/173 (34%), Positives = 90/173 (52%), Gaps = 3/173 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
++ GP G+ L QRL+ + + S V TTR+ R+ E G Y F SR+ F+A +
Sbjct 6 VITGPSGVGKGTLVQRLLARNPSIWVS-VSATTRAPREGEREGESYFFHSRERFDALVQE 64
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
G +E EF N YGT V Q + +G+ LL + + + +R S K IF+APPS
Sbjct 65 GGLLEWAEFAGNCYGTPRAPVEQQLQAGRPVLLEIELEGARQVRRSFSKARQIFLAPPSF 124
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
E L + G + + + +++ + + RE G FD +VN DLD+A +L
Sbjct 125 EELERRIRGRGTDSE-DAIQQRLLRAREELSAQGE-FDAVVVNDDLDQALLKL 175
>sp|Q88BE2|KGUA_PSESM Guanylate kinase OS=Pseudomonas syringae
pv. tomato (strain ATCC BAA-871 / DC3000) OX=223283 GN=gmk
PE=3 SV=1
Length=214
Score = 90.1 bits (222), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 63/197 (32%), Positives = 97/197 (49%), Gaps = 17/197 (9%)
Query 483 ILIGPQNCGQNELRQRLMNKEKD-------RFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
I+ P G+ L + LM+ +++ + +V HTTR+ R EV G +Y+FV R
Sbjct 10 IISAPSGAGKTSLVKALMDAQQEPQHGAQAKIRVSVSHTTRAMRPGEVDGVNYNFVDRAE 69
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F I G F+E E NLYGTS ++Q ++ G +L + Q + +R + I
Sbjct 70 FVRMIEHGDFLEQAEVFGNLYGTSQSHLQQTLDEGHDLILEIDWQGARQVRTQMPQARSI 129
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIE-KTREMEQNNGHY--FDTAIVNSDLDKAY 652
FI PPSQ+ LR L G++ EIIE + RE HY ++ +VN D A
Sbjct 130 FILPPSQQALRQRLTNRGQDSD-----EIIEARMREAVSEMSHYNEYEYVVVNDDFAGAL 184
Query 653 QELLRLI--NKLDTEPQ 667
++L + N+L + Q
Sbjct 185 EDLKSIFRANRLTQQHQ 201
>sp|Q4ZZY8|KGUA_PSEU2 Guanylate kinase OS=Pseudomonas syringae
pv. syringae (strain B728a) OX=205918 GN=gmk PE=3 SV=1
Length=214
Score = 90.1 bits (222), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 59/183 (32%), Positives = 92/183 (50%), Gaps = 15/183 (8%)
Query 483 ILIGPQNCGQNELRQRLMNKEKD-------RFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
I+ P G+ L + LM+ +++ + +V HTTR+ R EV G +Y+FV R
Sbjct 10 IISAPSGAGKTSLVKALMDAQQEPQHGAQAKIRVSVSHTTRAMRPGEVDGVNYNFVDRAT 69
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F + I G F+E E NLYGTS ++Q ++ G +L + Q + +R + I
Sbjct 70 FLSMIEHGDFLEQAEVFGNLYGTSQSHLQQTLDEGHDLILEIDWQGARQVRAQMPQARSI 129
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIE-KTREMEQNNGHY--FDTAIVNSDLDKAY 652
FI PP+Q+ LR L G++ EIIE + RE HY ++ +VN D A
Sbjct 130 FILPPTQQALRQRLTNRGQDSD-----EIIEARMREAVSEMSHYSEYEYVVVNDDFAGAL 184
Query 653 QEL 655
++L
Sbjct 185 EDL 187
>sp|Q5HPY1|KGUA_STAEQ Guanylate kinase OS=Staphylococcus epidermidis
(strain ATCC 35984 / RP62A) OX=176279 GN=gmk PE=3 SV=1
Length=207
Score = 89.7 bits (221), Expect = 4e-19, Method: Compositional matrix adjust.
Identities = 49/170 (29%), Positives = 84/170 (49%), Gaps = 2/170 (1%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +R+++ + ++ TTR R+ E+ G DY F +++ FEA I
Sbjct 9 IVLSGPSGVGKGTVRKKIFEDPTTSYKYSISMTTRHMREGEIDGVDYFFKTKEEFEALIK 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+FIE+ ++ N YGT + V+ + G L + + K +R IF+APPS
Sbjct 69 DDQFIEYAQYVGNYYGTPVQYVKDTMEEGHDVFLEIEVEGAKQVRKKFPDALFIFLAPPS 128
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
+ LR L G + + E +E+E N +D +VN +++ A
Sbjct 129 LDDLRERLVGRGTESDEKIQSRVNEARKEVEMMN--LYDYVVVNDEVELA 176
>sp|Q9HTM2|KGUA_PSEAE Guanylate kinase OS=Pseudomonas aeruginosa
(strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 /
LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=gmk PE=1 SV=1
Length=203
Score = 89.4 bits (220), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 61/176 (35%), Positives = 87/176 (49%), Gaps = 9/176 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I+ P G+ L + L++ + S V HTTR R EV G +YHF SR+ F A +
Sbjct 7 IVSAPSGAGKTSLVKALLDAAPEVRVS-VSHTTRGMRPGEVDGVNYHFTSREEFLAMLER 65
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
+F+EH E NLYGTS V + + G +L + Q + +R + IFI PPSQ
Sbjct 66 NEFLEHAEVFGNLYGTSQRWVEKTLAEGLDLILEIDWQGAQQVRRLMPEAQSIFILPPSQ 125
Query 603 ERLRALLAKEGKNPKPEELREIIE-KTREMEQNNGHY--FDTAIVNSDLDKAYQEL 655
E LR L G++ E+IE + RE HY +D ++N D A +L
Sbjct 126 EALRQRLTNRGQDSD-----EVIERRMREAVSEMSHYVEYDHLVINDDFAHALDDL 176
>sp|Q1QSI1|KGUA_CHRSD Guanylate kinase OS=Chromohalobacter salexigens
(strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB
13768 / 1H11) OX=290398 GN=gmk PE=3 SV=1
Length=215
Score = 89.7 bits (221), Expect = 5e-19, Method: Composition-based stats.
Identities = 62/193 (32%), Positives = 95/193 (49%), Gaps = 7/193 (4%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
QP ++ I+ P G+ L + L+ + +V HTTR+ R E G +YHFV
Sbjct 4 QPPSKGTLYIVSAPSGAGKTSLVRALLERVAG-IQVSVSHTTRAMRPGEQNGINYHFVDV 62
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
FE I +G FIEH N YGTS +V+ ++++G+ +L + Q + +R + +
Sbjct 63 ATFERLIESGDFIEHARVFDNYYGTSRAAVQALLDAGQDVILEIDWQGARQVREAFDEAV 122
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKA 651
IFI PPS+E L A LA G + R + + EM HY ++ I+N D A
Sbjct 123 SIFILPPSREALHARLAGRGTDDAATIARRMRDAVDEMS----HYDEYEHVIINDTFDHA 178
Query 652 YQELLRLINKLDT 664
EL L++ T
Sbjct 179 LDELSCLVHAQRT 191
>sp|P72648|KGUA_SYNY3 Guanylate kinase OS=Synechocystis sp. (strain
PCC 6803 / Kazusa) OX=1111708 GN=gmk PE=3 SV=1
Length=191
Score = 89.0 bits (219), Expect = 5e-19, Method: Compositional matrix adjust.
Identities = 58/188 (31%), Positives = 95/188 (51%), Gaps = 3/188 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
Q + + + I+L GP G+ L Q L+ ++ F S + TTRS R EV G+ Y+F+++
Sbjct 5 QTSVKGQLIVLTGPSGVGKGTLVQLLLERQPHWFLS-ISATTRSPRAGEVDGQSYYFLTK 63
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ F+ I K +E E+ N YGT V + I GK LL + + ++ +
Sbjct 64 EEFQTWIGEEKLLEWAEYAGNYYGTPRQPVEEQIAQGKTVLLEIEVLGARQIKQTFPSAR 123
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI PPS E L L G + + + + + +E++ FD +VN DLD+A
Sbjct 124 RIFILPPSVEVLEERLRGRGSDSETAIAKRLAQAQQELQAAA--EFDYQVVNDDLDQALH 181
Query 654 ELLRLINK 661
L++LI +
Sbjct 182 RLVKLIGE 189
>sp|Q0A5V3|KGUA_ALKEH Guanylate kinase OS=Alkalilimnicola ehrlichii
(strain ATCC BAA-1101 / DSM 17681 / MLHE-1) OX=187272
GN=gmk PE=3 SV=1
Length=203
Score = 89.0 bits (219), Expect = 6e-19, Method: Composition-based stats.
Identities = 59/176 (34%), Positives = 94/176 (53%), Gaps = 9/176 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
++ P G+ L L+ ++ + + +V HTTR R E G +YHFV R F+A +A
Sbjct 7 VVSAPSGAGKTSLVNALV-RQDEAVSLSVSHTTRPPRPGEEDGVNYHFVDRDRFQALVAQ 65
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
G F+EH E N YGTS +V+ +++ G+ +L + Q + +R +FI PPS+
Sbjct 66 GDFLEHAEVFGNHYGTSRSAVQALLDQGQDVILEIDWQGARQVRERMPGCLSVFILPPSR 125
Query 603 ERLRALLAKEGKNPKPEEL-REIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQEL 655
E LR L + G++ +PE + R + E EM HY +D +VN D D+ +L
Sbjct 126 EELRRRLTQRGQD-EPEVIDRRMAEAVSEMS----HYAEYDYLLVNDDFDRTLADL 176
>sp|Q5M3I4|KGUA_STRT2 Guanylate kinase OS=Streptococcus thermophilus
(strain ATCC BAA-250 / LMG 18311) OX=264199 GN=gmk PE=3
SV=1
Length=209
Score = 89.0 bits (219), Expect = 7e-19, Method: Compositional matrix adjust.
Identities = 55/178 (31%), Positives = 88/178 (49%), Gaps = 2/178 (1%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+ GP G+ +RQ + +K +F +V TTR++R EV G+DY F SR+ FE I
Sbjct 8 IVFSGPSGVGKGTVRQEIFSKSDHKFEYSVSMTTRAQRPGEVDGKDYFFRSREEFEELIR 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+ +E+ E+ N YGT + V + ++ G L + Q ++ IF+ PP
Sbjct 68 NGQMLEYAEYVGNYYGTPLAYVNETLDKGIDVFLEIEVQGALQVKKKVPDAVFIFLTPPD 127
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
L L G + + E + + IE+ RE Y D IVN ++ A + + R+I
Sbjct 128 LNELEERLVGRGTDSE-EVIAQRIERAREEIALMSEY-DYTIVNDEVPLAAERVKRVI 183
>sp|Q5LYX1|KGUA_STRT1 Guanylate kinase OS=Streptococcus thermophilus
(strain CNRZ 1066) OX=299768 GN=gmk PE=3 SV=1
Length=209
Score = 89.0 bits (219), Expect = 7e-19, Method: Compositional matrix adjust.
Identities = 55/178 (31%), Positives = 88/178 (49%), Gaps = 2/178 (1%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+ GP G+ +RQ + +K +F +V TTR++R EV G+DY F SR+ FE I
Sbjct 8 IVFSGPSGVGKGTVRQEIFSKSDHKFEYSVSMTTRAQRPGEVDGKDYFFRSREEFEELIR 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+ +E+ E+ N YGT + V + ++ G L + Q ++ IF+ PP
Sbjct 68 NGQMLEYAEYVGNYYGTPLAYVNETLDKGIDVFLEIEVQGALQVKKKVPDAVFIFLTPPD 127
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
L L G + + E + + IE+ RE Y D IVN ++ A + + R+I
Sbjct 128 LNELEERLVGRGTDSE-EVIAQRIERAREEIALMSEY-DYTIVNDEVPLAAERVKRVI 183
>sp|Q9JT96|KGUA_NEIMA Guanylate kinase OS=Neisseria meningitidis
serogroup A / serotype 4A (strain DSM 15465 / Z2491) OX=122587
GN=gmk PE=3 SV=1
Length=205
Score = 89.0 bits (219), Expect = 8e-19, Method: Composition-based stats.
Identities = 61/186 (33%), Positives = 95/186 (51%), Gaps = 4/186 (2%)
Query 476 ANRKRPIILI-GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
A RK I +I G+ L RL+ + +V HTTR R+ E G YHFVS++
Sbjct 3 AYRKGNIFIISAASGTGKTTLVSRLL-ANHNGLRVSVSHTTRPPREGEANGVHYHFVSKE 61
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
FE+ IA F+E+ + N YGTS + V + +G +L + Q +R++ +
Sbjct 62 EFESLIAQEAFLEYADVFGNYYGTSAEGVNALAAAGYDVILEIDVQGAAQVRDALPEAVG 121
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFI PPS + L A L G + + R + + E+EQ+ FD +VN DL +A ++
Sbjct 122 IFILPPSFDVLAARLNGRGTDSREVIQRRLSKARHEIEQSV--LFDFVVVNDDLARAEED 179
Query 655 LLRLIN 660
L ++N
Sbjct 180 LRHIVN 185
>sp|Q9KX62|KGUA_MYCGA Guanylate kinase OS=Mycoplasmoides gallisepticum
(strain R(low / passage 15 / clone 2)) OX=710127 GN=gmk
PE=3 SV=2
Length=195
Score = 88.6 bits (218), Expect = 8e-19, Method: Compositional matrix adjust.
Identities = 54/196 (28%), Positives = 103/196 (53%), Gaps = 3/196 (2%)
Query 469 MSLYHQPANRKRPIILI-GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRD 527
M + + +N++ IILI GP G+ + RL++ + ++ TTR +R EV G
Sbjct 1 MVVIYIMSNKQGLIILISGPSGVGKGTIVSRLLSDNNLKLNVSISATTRKKRASEVEGVH 60
Query 528 YHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN 587
Y F +++ FE IA + +E+ + N YGT + V+++++ + +L + Q + +
Sbjct 61 YFFKTKEEFEQMIANNQLLEYANYVNNYYGTPLSLVKEILDKNENLILEIEYQGVIQVLR 120
Query 588 SDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD 647
+ IF+ PPS++ L A L K G E ++ +E+ + E + +D I+N D
Sbjct 121 KGFRTLSIFVLPPSEDELVARLKKRG-TENDEVIKHRLEQAVK-EYAHRELYDHTIINDD 178
Query 648 LDKAYQELLRLINKLD 663
L+K +++ +LI K +
Sbjct 179 LEKTIEDIKQLILKYN 194
>sp|Q0I868|KGUA_SYNS3 Guanylate kinase OS=Synechococcus sp. (strain
CC9311) OX=64471 GN=gmk PE=3 SV=1
Length=190
Score = 88.2 bits (217), Expect = 9e-19, Method: Compositional matrix adjust.
Identities = 58/181 (32%), Positives = 87/181 (48%), Gaps = 3/181 (2%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
RP +L GP G+ L RL + + + S V TTR+ R E+ G Y F S++ F
Sbjct 9 RPTVLTGPSGVGKGTLVARLRERHPEIWLS-VSATTRAPRSGEIDGIHYFFHSKERFNKL 67
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
+ +G +E EF N YGT + V + + +G LL + + + +R S + IF+AP
Sbjct 68 VQSGGLLEWAEFAGNCYGTPREPVSERVANGIPVLLEIELEGARQVRKSLPEAIQIFLAP 127
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
PS E L + G + R + E+E FD IVN DL+ A EL + +
Sbjct 128 PSVEELEKRIRGRGTEAEEAIQRRLKRAQEELEAQT--EFDAVIVNDDLETALAELEKQM 185
Query 660 N 660
N
Sbjct 186 N 186
>sp|Q73HV1|KGUA_WOLPM Guanylate kinase OS=Wolbachia pipientis
wMel OX=163164 GN=gmk PE=3 SV=2
Length=201
Score = 88.6 bits (218), Expect = 9e-19, Method: Compositional matrix adjust.
Identities = 55/183 (30%), Positives = 93/183 (51%), Gaps = 10/183 (5%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++L P G+ + +L+ + + +V TTR R E+ G+DY FV+ + F
Sbjct 10 LVLSSPSGAGKTTISAKLLEQSTN-LVRSVSMTTRKPRPGEINGKDYFFVTEEKFHELCK 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS----LKTLRNSDLKPYIIFI 597
AG+ +E+ + +N YG D + Q ++SG LLS+ Q K +R K +FI
Sbjct 69 AGQMLEYAKVFENFYGIPRDFIEQNLSSGISVLLSIDWQGAFHLFKLMRK---KVVSVFI 125
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS E LR L K + E R + E +E+ + + +D I+N D+DK+ +E+
Sbjct 126 LPPSMEELRLRLQKRNSDDASEIERRLAEAQKEISKRDK--YDYVIINDDIDKSVEEISS 183
Query 658 LIN 660
++N
Sbjct 184 ILN 186
>sp|P0C0M9|KGUA_STAES Guanylate kinase OS=Staphylococcus epidermidis
(strain ATCC 12228 / FDA PCI 1200) OX=176280 GN=gmk PE=3
SV=1
Length=207
Score = 88.6 bits (218), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 48/170 (28%), Positives = 84/170 (49%), Gaps = 2/170 (1%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +R+++ + ++ TTR R+ E+ G DY F +++ FEA I
Sbjct 9 IVLSGPSGVGKGTVRKKIFEDPTTSYKYSISMTTRHMREGEIDGVDYFFKTKEEFEALIK 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+FIE+ ++ N YGT + V+ + G L + + K +R IF+APPS
Sbjct 69 DDQFIEYAQYVGNYYGTPVQYVKDTMEEGHDVFLEIEVEGAKQVRKKFPDALFIFLAPPS 128
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
+ L+ L G + + E +E+E N +D +VN +++ A
Sbjct 129 LDDLKERLVGRGTESDEKIQSRVNEARKEVEMMN--LYDYVVVNDEVELA 176
>sp|Q1G9H8|KGUA_LACDA Guanylate kinase OS=Lactobacillus delbrueckii
subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / BCRC
10696 / JCM 1002 / NBRC 13953 / NCIMB 11778 / NCTC 12712 /
WDCM 00102 / Lb 14) OX=390333 GN=gmk PE=3 SV=1
Length=204
Score = 88.2 bits (217), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 53/185 (29%), Positives = 97/185 (52%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A++ ++L GP G+ ++ ++ + F +V TTR R+ EV G+DY+FV+R+
Sbjct 2 ADKGLLLVLSGPSGVGKGTVKSAIVEHKVFPFEYSVSMTTRKPREGEVNGKDYYFVTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F+ IA + +E+ E+ NLYGT + V++++ +GK LL + +T+R + I
Sbjct 62 FKQAIADNQLLEYNEYVGNLYGTPLGPVKEMLAAGKDVLLEIDVNGARTVRQQMPEGVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP LR L G + + +R I + R+ E +D A+VN + A +
Sbjct 122 FLTPPDLHTLRDRLEHRGTESE-DVIRGRIAQARK-EILVMQDYDYAVVNDTVANAVNHI 179
Query 656 LRLIN 660
+++
Sbjct 180 KAIVD 184
>sp|Q48Q15|KGUA_PSE14 Guanylate kinase OS=Pseudomonas savastanoi
pv. phaseolicola (strain 1448A / Race 6) OX=264730 GN=gmk
PE=3 SV=2
Length=214
Score = 88.6 bits (218), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 59/183 (32%), Positives = 91/183 (50%), Gaps = 15/183 (8%)
Query 483 ILIGPQNCGQNELRQRLMNKEKD-------RFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
I+ P G+ L + LM+ +++ + +V HTTR+ R EV G +Y+FV R
Sbjct 10 IISAPSGAGKTSLVKALMDAQQEPQHGAQAKIRVSVSHTTRAMRPGEVNGVNYNFVDRAE 69
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F I G F+E E NLYGTS ++Q ++ G +L + Q + +R + I
Sbjct 70 FVRMIEHGDFLEQAEVFGNLYGTSQSHLQQTLDEGHDLILEIDWQGARQVRAQMPQARSI 129
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIE-KTREMEQNNGHY--FDTAIVNSDLDKAY 652
FI PP+Q+ LR L G++ EIIE + RE HY ++ +VN D A
Sbjct 130 FILPPTQQALRQRLTNRGQDSD-----EIIEARMREAVSEMSHYNEYEYVVVNDDFAGAL 184
Query 653 QEL 655
++L
Sbjct 185 EDL 187
>sp|Q1MRL0|KGUA_LAWIP Guanylate kinase OS=Lawsonia intracellularis
(strain PHE/MN1-00) OX=363253 GN=gmk PE=3 SV=1
Length=212
Score = 88.2 bits (217), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 55/174 (32%), Positives = 85/174 (49%), Gaps = 3/174 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ P G+ L QRL KE FA ++ TTR R E G+DY+F+S++ F A
Sbjct 17 LVICAPSGTGKTTLIQRL-RKEFPCFAYSISCTTRPPRKNEEDGKDYYFISQEEFIARKN 75
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
F E YGT + + ++N+G+ L + Q L + IF+ PP+
Sbjct 76 EKYFAEWAYVHGYFYGTPLAPILTILNNGQDILFDIDVQGAAQLYLTLPYAKYIFLLPPT 135
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
L L G + + ++ T+E+ Q H+FDT IVN ++DKAY EL
Sbjct 136 MVELEKRLRSRGTDREDIIQHRLLSATQEIRQ--AHWFDTWIVNENIDKAYDEL 187
>sp|Q96M69|LRGUK_HUMAN Leucine-rich repeat and guanylate kinase
domain-containing protein OS=Homo sapiens OX=9606 GN=LRGUK
PE=1 SV=1
Length=825
Score = 93.6 bits (231), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 55/180 (31%), Positives = 90/180 (50%), Gaps = 2/180 (1%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+IL GP+ CG+ EL RL + F HTTR E DYHF+S+ F+ +
Sbjct 417 LILAGPEACGKRELAHRLCRQFSTYFRYGACHTTRPPYFGEGDRVDYHFISQDVFDEMVN 476
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
GKFI + + YG + D+V + G + + + +++L+ S +P I + P +
Sbjct 477 MGKFILTFSYGNHKYGLNRDTVEGIARDGLASCIHMEIEGVRSLKYSYFEPRYILVVPMN 536
Query 602 QERLRALLAKEGKNPKPEELREI--IEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
+E+ L ++G + E + ++ ++ QN YFD I DLD AYQ+L +LI
Sbjct 537 KEKYEGYLRRKGLFSRAEIEFAVSRVDLYIKINQNFPGYFDEVINADDLDVAYQKLSQLI 596
>sp|Q5N570|KGUA_SYNP6 Guanylate kinase OS=Synechococcus sp. (strain
ATCC 27144 / PCC 6301 / SAUG 1402/1) OX=269084 GN=gmk
PE=3 SV=1
Length=183
Score = 86.7 bits (213), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 51/176 (29%), Positives = 88/176 (50%), Gaps = 3/176 (2%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
R ++L GP G+ L + ++++ + F S + TTRS R EV G+ Y+F+SR+ F+
Sbjct 5 RVVVLTGPSGVGKGTLLKAILSQHPEAFLS-ISATTRSPRPGEVDGQHYYFLSREEFQTK 63
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
IA +F+E EF NLYGT V + +N G+ +L + + + +R + + + P
Sbjct 64 IAEQEFLEWAEFAGNLYGTPRSPVIEQVNLGRTVILEIELEGARQVRKTLPSARQVVLLP 123
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
PS E L + + + R +++ E+ FD ++N LD A L
Sbjct 124 PSVEELEQRIRERATEDEAAIARRLLQAQTEI--GAAKEFDRCVINDQLDTAITAL 177
>sp|Q9JYB5|KGUA_NEIMB Guanylate kinase OS=Neisseria meningitidis
serogroup B (strain MC58) OX=122586 GN=gmk PE=3 SV=1
Length=205
Score = 87.4 bits (215), Expect = 3e-18, Method: Composition-based stats.
Identities = 60/186 (32%), Positives = 94/186 (51%), Gaps = 4/186 (2%)
Query 476 ANRKRPIILI-GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
A RK I +I G+ L RL+ + +V HTTR R+ E G YHFVS++
Sbjct 3 AYRKGNIFIISAASGTGKTTLVSRLL-ANHNGLRVSVSHTTRPPREGEANGVHYHFVSKE 61
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
FE+ IA F+E+ + N YGT + V + +G +L + Q +R++ +
Sbjct 62 EFESLIAQEAFLEYADVFGNYYGTGAEGVNALAAAGYDVILEIDVQGAAQVRDALPEAVG 121
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFI PPS + L A L G + + R + + E+EQ+ FD +VN DL +A ++
Sbjct 122 IFILPPSFDVLAARLNGRGTDSREVIQRRLSKARHEIEQSV--LFDFVVVNDDLARAEED 179
Query 655 LLRLIN 660
L ++N
Sbjct 180 LRHIVN 185
>sp|Q65JT0|KGUA_BACLD Guanylate kinase OS=Bacillus licheniformis
(strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC
12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46)
OX=279010 GN=gmk PE=3 SV=1
Length=204
Score = 87.0 bits (214), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 46/132 (35%), Positives = 67/132 (51%), Gaps = 0/132 (0%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +RQ L +E +F ++ TTR R E G DY F +R+ FE I
Sbjct 8 IVLSGPSGVGKGTVRQALFAQEDTKFEYSISVTTRKPRQGERDGVDYFFKTREEFEEMIE 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
K +E E+ N YGT +D V Q + SG+ L + Q +R + + IF+APPS
Sbjct 68 NNKLLEWAEYVGNYYGTPVDYVEQTLESGRDVFLEIEVQGALQVRKAFPEGLFIFLAPPS 127
Query 602 QERLRALLAKEG 613
L+ + G
Sbjct 128 LAELKNRIVTRG 139
>sp|Q7V2K9|KGUA_PROMP Guanylate kinase OS=Prochlorococcus marinus
subsp. pastoris (strain CCMP1986 / NIES-2087 / MED4) OX=59919
GN=gmk PE=3 SV=1
Length=184
Score = 86.7 bits (213), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 53/183 (29%), Positives = 94/183 (51%), Gaps = 3/183 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N K+ II+ GP G+ + + L+++ KD + S + TTR+ R E +Y+F+ + F
Sbjct 3 NLKKLIIITGPSGVGKGTVIKELLDRNKDIWLS-ISATTRNPRVGEKDDLNYYFIGEERF 61
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I +F+E +F N YGT + +V + I G I LL + + K ++ + IF
Sbjct 62 KDMIDKKEFLEWAQFAGNYYGTPLSTVNEKIEKGFIVLLEIEVEGAKQIKEKFPESLSIF 121
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+ PPS+E L + G + R + E+ +N FD + N D+D+ +E+L
Sbjct 122 LLPPSKEELEKRIRNRGTEKEEAIDRRLSRANYEIASSN--QFDFVLTNHDVDETVKEVL 179
Query 657 RLI 659
++I
Sbjct 180 KII 182
>sp|Q5YTM7|KGUA_NOCFA Guanylate kinase OS=Nocardia farcinica (strain
IFM 10152) OX=247156 GN=gmk PE=3 SV=1
Length=193
Score = 86.7 bits (213), Expect = 4e-18, Method: Composition-based stats.
Identities = 59/183 (32%), Positives = 95/183 (52%), Gaps = 5/183 (3%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ R ++L+GP G++ + R + + +V TTR+ R EV GRDY FV+R F+
Sbjct 7 KGRLVVLVGPSAVGKSTV-VRCVRERLPELVFSVSATTRAPRPGEVDGRDYRFVTRAEFD 65
Query 538 ADIAAGKFIEHGEFEKNLY--GTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
A I AG+ +E E L GT VR+ + +GK LL + + +++R + ++
Sbjct 66 AMIEAGELLEWAEIHGGLQRSGTPAAPVREALAAGKNVLLEVDLEGARSVRKVMPEARLV 125
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+APPS + L A L G PE + +E R +E FD IVN ++ A ++L
Sbjct 126 FLAPPSWDELVARLTARGTE-TPEVIARRLETAR-IELAACDEFDNVIVNDEVTSACEQL 183
Query 656 LRL 658
+ L
Sbjct 184 VSL 186
>sp|Q9RS38|KGUA_DEIRA Guanylate kinase OS=Deinococcus radiodurans
(strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074
/ LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1) OX=243230
GN=gmk PE=3 SV=2
Length=239
Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 60/183 (33%), Positives = 88/183 (48%), Gaps = 5/183 (3%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
P R I++ G G+ LR+R + + D F S TTR R EV GRDY FVS
Sbjct 15 PQGRGLLIVVTGASGVGKGTLRERWLAGQ-DVFYS-TSWTTREPRPGEVNGRDYVFVSPA 72
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS-DLKPY 593
F A F+EH +F N YGT I+ + + G+ +L + + +++ +
Sbjct 73 EFLAKAQQNGFLEHAQFVGNHYGTPIEPIEAALERGQDVVLEIEVEGAMQVKDRMGEQAI 132
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
++FI PPS LR L PE + + + + R+ E H F IVN +LD+A
Sbjct 133 LVFIMPPSLTELRRRLTGRATE-TPERIEKRLTRARD-EIQAAHDFRYVIVNDNLDRAVS 190
Query 654 ELL 656
ELL
Sbjct 191 ELL 193
>sp|Q67PR9|KGUA_SYMTH Guanylate kinase OS=Symbiobacterium thermophilum
(strain T / IAM 14863) OX=292459 GN=gmk PE=3 SV=1
Length=211
Score = 86.7 bits (213), Expect = 5e-18, Method: Composition-based stats.
Identities = 59/179 (33%), Positives = 87/179 (49%), Gaps = 5/179 (3%)
Query 482 IILIGPQNCGQNEL-RQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I++ GP G+ + R L RF+ V TTR +R EV G +Y+F+S++ FE I
Sbjct 10 IVVTGPSAVGKGTICRALLAETPGIRFS--VSCTTRPKRPGEVDGVEYYFISKEEFERRI 67
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
AAG+F+E E N YGT V +V G+ +L + + +R +F+ PP
Sbjct 68 AAGEFLEWAEVYGNYYGTPRGYVEEVTAQGQDVILDIDRVGARAVREQYPDAVSVFVIPP 127
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
S E LR +A G R + E + + G +D IVN DL +A EL +I
Sbjct 128 SMEALRQRIAARGTESPEAVARRLAEAPEWIRE--GLTYDYVIVNDDLARAVAELRAII 184
>sp|Q15Z10|KGUA_PSEA6 Guanylate kinase OS=Pseudoalteromonas atlantica
(strain T6c / ATCC BAA-1087) OX=3042615 GN=gmk PE=3
SV=1
Length=215
Score = 86.3 bits (212), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 58/192 (30%), Positives = 91/192 (47%), Gaps = 8/192 (4%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKE------KDRFASAVPHTTRSRRDQEVAGRDY 528
P + IL P G++ L + L+ + +V HTTR+ R E+ G Y
Sbjct 2 PQSLGNLFILAAPSGAGKSSLIKALLQNHDATEIHNNEMQVSVSHTTRAPRPGEIDGVHY 61
Query 529 HFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS 588
HFVSR+ F+ I +F E E N YGTS + Q + G L + Q + ++
Sbjct 62 HFVSRKVFQELITQDEFFEWAEVFGNYYGTSKVVIEQTLRKGIDVFLDIDWQGARQVKAQ 121
Query 589 DLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDL 648
IF+APPS+E L L + G++ PE +++ + K E ++ H FD +VN D
Sbjct 122 IPDTATIFVAPPSREELMRRLTERGQD-TPEVIQDRMNKAVS-EISHYHEFDYIVVNDDF 179
Query 649 DKAYQELLRLIN 660
A EL +++
Sbjct 180 TAALAELDAIVS 191
>sp|Q88WL7|KGUA_LACPL Guanylate kinase OS=Lactiplantibacillus
plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) OX=220668
GN=gmk PE=3 SV=1
Length=206
Score = 86.3 bits (212), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 46/178 (26%), Positives = 89/178 (50%), Gaps = 2/178 (1%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +R+ + + + + F +V TTR R EV G+DY+FVS++ FE +I
Sbjct 8 IVLSGPSGVGKGTVRKEIFDSDDNDFQYSVSMTTRQMRPGEVDGKDYYFVSKEEFEDEIK 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+G +E+ ++ N YGT + ++Q + +GK L + +R IF+ PP
Sbjct 68 SGGMLEYAKYVDNYYGTPLKYIKQSLAAGKDVFLEIEVNGAMQVREKMPDGVFIFLTPPD 127
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
L+ + G + + + + E++ +D A++N ++ A + + +I
Sbjct 128 LMELKHRIIGRGTDDMSVINKRMAKAVDEIKMMRN--YDYAVINDEVPLAAERIKAII 183
>sp|Q8DNR5|KGUA_STRR6 Guanylate kinase OS=Streptococcus pneumoniae
(strain ATCC BAA-255 / R6) OX=171101 GN=gmk PE=3 SV=1
Length=208
Score = 85.9 bits (211), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 53/176 (30%), Positives = 87/176 (49%), Gaps = 2/176 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A+R I+ GP G+ +R+ + +++F +V TTR++R EV G DY F +R+
Sbjct 2 ADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q ++ I
Sbjct 62 FEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKKKVPDAVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
F+ PP + L+ L G + E + + IEK +E E +D AIVN + A
Sbjct 122 FLTPPDLDELQDRLVGRGTD-SAEVIAQRIEKAKE-EIALMREYDYAIVNDQVSLA 175
>sp|Q5GS56|KGUA_WOLTR Guanylate kinase OS=Wolbachia sp. subsp.
Brugia malayi (strain TRS) OX=292805 GN=gmk PE=3 SV=1
Length=195
Score = 85.1 bits (209), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 53/184 (29%), Positives = 93/184 (51%), Gaps = 10/184 (5%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++L P G+ + +RL+ + + +V TTR R E+ G+DY FV+++ F
Sbjct 10 LVLSSPSGAGKTTILERLLERSTN-LVRSVSMTTRKPRPGEINGKDYFFVTKKEFHELCE 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS----LKTLRNSDLKPYIIFI 597
AG+ +E+ +N YG + Q ++SG LLS+ Q + +R K +FI
Sbjct 69 AGQMLEYARVFENFYGIPKSFIEQNLSSGISVLLSIDWQGAFHLFELMRE---KVISVFI 125
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS E LR L K + E + E +EM + + +D ++N D+DK+ +E+
Sbjct 126 LPPSMEELRLRLQKRNSDSASEIEHRLAEAQKEMSKRDK--YDYVVINDDIDKSVEEISS 183
Query 658 LINK 661
+++K
Sbjct 184 ILDK 187
>sp|Q92AI1|KGUA_LISIN Guanylate kinase OS=Listeria innocua serovar
6a (strain ATCC BAA-680 / CLIP 11262) OX=272626 GN=gmk
PE=3 SV=1
Length=205
Score = 85.5 bits (210), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 53/176 (30%), Positives = 86/176 (49%), Gaps = 6/176 (3%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +R+ + + F ++ TTR R+ E G DY+F SR+ FE I
Sbjct 8 IVLSGPSGVGKGTVREAVFKDPETSFDYSISMTTRLPREGEQDGVDYYFRSREVFEQAIK 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
GK +E+ E+ N YGT ++ V + + +G L + Q +R + + IF+ PP
Sbjct 68 DGKMLEYAEYVGNYYGTPLEYVEEKLAAGIDIFLEIEVQGAMQVRKAMPEGIFIFLTPPD 127
Query 602 QERLRALLAKEGKNPKP--EELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
L+ + G EE E +K EM + +D A+VN + KA Q++
Sbjct 128 LSELKNRIIGRGTESMEVVEERMETAKKEIEMMAS----YDYAVVNDVVSKAVQKI 179
>sp|Q97PA3|KGUA_STRPN Guanylate kinase OS=Streptococcus pneumoniae
serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=gmk
PE=3 SV=1
Length=208
Score = 85.5 bits (210), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 52/170 (31%), Positives = 85/170 (50%), Gaps = 2/170 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A+R I+ GP G+ +R+ + +++F +V TTR++R EV G DY F +R+
Sbjct 2 ADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q ++ I
Sbjct 62 FEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKKKVPDAVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVN 645
F+ PP + L+ L G + E + + IEK +E E +D AIVN
Sbjct 122 FLTPPDLDELQDRLVGRGTD-SAEVIAQRIEKAKE-EIALMREYDYAIVN 169
>sp|P0DB95|KGUA_STRPQ Guanylate kinase OS=Streptococcus pyogenes
serotype M3 (strain SSI-1) OX=193567 GN=gmk PE=3 SV=1
Length=211
Score = 85.1 bits (209), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 52/184 (28%), Positives = 91/184 (49%), Gaps = 2/184 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + E + + IE+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQ-EVIAQRIERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLI 659
R+I
Sbjct 180 KRII 183
>sp|Q48S18|KGUA_STRPM Guanylate kinase OS=Streptococcus pyogenes
serotype M28 (strain MGAS6180) OX=319701 GN=gmk PE=3 SV=1
Length=211
Score = 85.1 bits (209), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 52/184 (28%), Positives = 91/184 (49%), Gaps = 2/184 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + E + + IE+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQ-EVIAQRIERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLI 659
R+I
Sbjct 180 KRII 183
>sp|Q1J5I6|KGUA_STRPF Guanylate kinase OS=Streptococcus pyogenes
serotype M4 (strain MGAS10750) OX=370554 GN=gmk PE=3 SV=1
Length=211
Score = 85.1 bits (209), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 52/184 (28%), Positives = 91/184 (49%), Gaps = 2/184 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + E + + IE+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQ-EVIAQRIERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLI 659
R+I
Sbjct 180 KRII 183
>sp|Q1JFN7|KGUA_STRPD Guanylate kinase OS=Streptococcus pyogenes
serotype M2 (strain MGAS10270) OX=370552 GN=gmk PE=3 SV=1
Length=211
Score = 85.1 bits (209), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 52/184 (28%), Positives = 91/184 (49%), Gaps = 2/184 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + E + + IE+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQ-EVIAQRIERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLI 659
R+I
Sbjct 180 KRII 183
>sp|Q1JKP6|KGUA_STRPC Guanylate kinase OS=Streptococcus pyogenes
serotype M12 (strain MGAS9429) OX=370551 GN=gmk PE=3 SV=1
Length=211
Score = 85.1 bits (209), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 52/184 (28%), Positives = 91/184 (49%), Gaps = 2/184 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + E + + IE+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQ-EVIAQRIERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLI 659
R+I
Sbjct 180 KRII 183
>sp|Q1JAJ4|KGUA_STRPB Guanylate kinase OS=Streptococcus pyogenes
serotype M12 (strain MGAS2096) OX=370553 GN=gmk PE=3 SV=1
Length=211
Score = 85.1 bits (209), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 52/184 (28%), Positives = 91/184 (49%), Gaps = 2/184 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + E + + IE+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQ-EVIAQRIERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLI 659
R+I
Sbjct 180 KRII 183
>sp|P65223|KGUA_STRP8 Guanylate kinase OS=Streptococcus pyogenes
serotype M18 (strain MGAS8232) OX=186103 GN=gmk PE=3 SV=1
Length=211
Score = 85.1 bits (209), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 52/184 (28%), Positives = 91/184 (49%), Gaps = 2/184 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + E + + IE+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQ-EVIAQRIERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLI 659
R+I
Sbjct 180 KRII 183
>sp|Q5XAP1|KGUA_STRP6 Guanylate kinase OS=Streptococcus pyogenes
serotype M6 (strain ATCC BAA-946 / MGAS10394) OX=286636 GN=gmk
PE=3 SV=1
Length=211
Score = 85.1 bits (209), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 52/184 (28%), Positives = 91/184 (49%), Gaps = 2/184 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + E + + IE+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQ-EVIAQRIERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLI 659
R+I
Sbjct 180 KRII 183
>sp|P0DB94|KGUA_STRP3 Guanylate kinase OS=Streptococcus pyogenes
serotype M3 (strain ATCC BAA-595 / MGAS315) OX=198466 GN=gmk
PE=3 SV=1
Length=211
Score = 85.1 bits (209), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 52/184 (28%), Positives = 91/184 (49%), Gaps = 2/184 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + E + + IE+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQ-EVIAQRIERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLI 659
R+I
Sbjct 180 KRII 183
>sp|Q3ALX6|KGUA_SYNSC Guanylate kinase OS=Synechococcus sp. (strain
CC9605) OX=110662 GN=gmk PE=3 SV=1
Length=185
Score = 84.3 bits (207), Expect = 2e-17, Method: Composition-based stats.
Identities = 55/177 (31%), Positives = 86/177 (49%), Gaps = 3/177 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
++ GP G+ L +L+ + + S V TTRS R E G +Y F SR FEA +
Sbjct 9 LITGPSGVGKGTLVNQLLERHPQIWLS-VSATTRSPRQGEQDGINYFFHSRAGFEALVEQ 67
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
G F+E EF N YGT V Q + +G+ LL + + + +R S + IF+APPS
Sbjct 68 GGFLEWAEFAGNCYGTPRGPVEQQMAAGRPVLLEIELEGARQVRRSFPDGFQIFLAPPSF 127
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
+ L + G + + R + E+E FD ++N DL+ A ++ L+
Sbjct 128 DELERRIRGRGTDSEDAIQRRLTRAREELEAQ--QEFDAVVINDDLESALNQVETLM 182
>sp|Q99YM5|KGUA_STRP1 Guanylate kinase OS=Streptococcus pyogenes
serotype M1 OX=301447 GN=gmk PE=3 SV=1
Length=211
Score = 85.1 bits (209), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 52/184 (28%), Positives = 91/184 (49%), Gaps = 2/184 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + E + + IE+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQ-EVIAQRIERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLI 659
R+I
Sbjct 180 KRII 183
>sp|Q7WZE5|KGUA_SHEVD Guanylate kinase OS=Shewanella violacea
(strain JCM 10179 / CIP 106290 / LMG 19151 / DSS12) OX=637905
GN=gmk PE=3 SV=1
Length=207
Score = 85.1 bits (209), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 57/183 (31%), Positives = 86/183 (47%), Gaps = 4/183 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLM-NKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R I+ P G++ L L+ +K D+ S V HTTR R EV G+ YHFV+++ F
Sbjct 4 RGNLFIVSAPSGAGKSSLISALLQDKPADKQVS-VSHTTRQPRPGEVNGQHYHFVTKEEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+A I F E E N YGTS + Q + G L + Q + ++ + IF
Sbjct 63 KALITENAFFEWAEVFGNYYGTSRKVIEQTLTDGIDVFLDIDWQGAQQVKKVMPEAIGIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+ L L G++ K + + E+ N +D I+N D D A +L+
Sbjct 123 ILPPSRTELEKRLTGRGQDSKEVIASRMAQAASEISHYN--EYDFIIINDDFDTALADLV 180
Query 657 RLI 659
+I
Sbjct 181 AII 183
>sp|Q31C67|KGUA_PROM9 Guanylate kinase OS=Prochlorococcus marinus
(strain MIT 9312) OX=74546 GN=gmk PE=3 SV=1
Length=184
Score = 83.6 bits (205), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 49/183 (27%), Positives = 94/183 (51%), Gaps = 3/183 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N+K+ IIL GP G+ + + ++ K+K+ + S + TTR R+ E G +Y+F+ ++ F
Sbjct 3 NQKKLIILTGPSGVGKGTVIKEILGKDKNIWLS-ISATTREPREGEQEGENYYFLKQEKF 61
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I F+E +F N YGT + SV + I G LL + + K ++ + IF
Sbjct 62 KEMIEKNLFLEWAQFAGNYYGTPLSSVNEKITKGFTVLLEIEVEGAKQIKEKFPESLSIF 121
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+ PP + L + G + + ++ + E+ +N FD + N ++D+ + ++
Sbjct 122 LLPPDKAELERRIRNRGTEKEEAIKKRLLRASYEISASN--QFDFELTNHNVDETAKRII 179
Query 657 RLI 659
+LI
Sbjct 180 KLI 182
>sp|Q2S8R2|KGUA_HAHCH Guanylate kinase OS=Hahella chejuensis (strain
KCTC 2396) OX=349521 GN=gmk PE=3 SV=1
Length=208
Score = 84.3 bits (207), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 59/180 (33%), Positives = 84/180 (47%), Gaps = 7/180 (4%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R + I+ P G+ L L+ ++K S + HTTR R E G +Y F+SR+ F
Sbjct 3 RGQLYIISAPSGAGKTSLVSALLKEDKLAQVS-ISHTTRQVRPGEQDGVNYFFISREEFL 61
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
A AG F+EH E N YGTS V + G +L + Q + +R + IFI
Sbjct 62 AQAQAGDFLEHAEVFGNFYGTSQAWVESTLAKGVDVILEIDWQGAQQVRKLRPEAKSIFI 121
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQEL 655
PPS E L+ L G++ R + E E+ HY +D + N D D A +EL
Sbjct 122 LPPSLEALQQRLESRGQDSAEVIQRRLQEAANEI----SHYPEYDYLVFNDDFDHALEEL 177
>sp|Q4K3R4|KGUA_PSEF5 Guanylate kinase OS=Pseudomonas fluorescens
(strain ATCC BAA-477 / NRRL B-23932 / Pf-5) OX=220664 GN=gmk
PE=3 SV=1
Length=206
Score = 84.0 bits (206), Expect = 3e-17, Method: Compositional matrix adjust.
Identities = 58/176 (33%), Positives = 87/176 (49%), Gaps = 9/176 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I+ P G++ L + L + K +V HTTR+ R EV G +YHFVSR+ F
Sbjct 10 IISAPSGAGKSSLVKALTDA-KPEIRVSVSHTTRAMRPGEVDGVNYHFVSRETFVKMGEH 68
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
G F+E E NLYGTS ++Q +++G +L + Q + +R + IFI PPS
Sbjct 69 GDFLERAEVFGNLYGTSQSHLQQTLDAGHDLILEIDWQGAEQVRKLMPQARSIFILPPSL 128
Query 603 ERLRALLAKEGKNPKPEELREIIE-KTREMEQNNGHY--FDTAIVNSDLDKAYQEL 655
+ L L G++ E+I+ + RE HY +D I+N D A +L
Sbjct 129 QALHQRLTNRGQDSD-----EVIDGRMREAVSEMSHYVDYDYLIINDDFAHALGDL 179
>sp|Q8KFS5|KGUA_CHLTE Guanylate kinase OS=Chlorobaculum tepidum
(strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS) OX=194439
GN=gmk PE=3 SV=1
Length=195
Score = 83.6 bits (205), Expect = 4e-17, Method: Composition-based stats.
Identities = 64/198 (32%), Positives = 98/198 (49%), Gaps = 12/198 (6%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFAS---AVPHTTRSRRDQEVAGRDYHF 530
Q ++ R I+ P G++ + + +M +R S +V TTR R E G DYHF
Sbjct 5 QVLDQGRLIVFSAPSGTGKSTVAKLVM----ERLGSLEFSVSATTRQMRAGERDGVDYHF 60
Query 531 VSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQ-SLKTLRNSD 589
+SR+ FE IA FIEH F N YGT +D I +G L L + +L R
Sbjct 61 LSREEFEKKIAENGFIEHEFFFGNFYGTLLDKTIDAIKAGHNLLFDLDVKGALNLKRIFG 120
Query 590 LKPYIIFIAPPSQERL-RALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDL 648
+ ++F+ PPS E L R L A++ ++ E L+ +E+ EME ++ FD +VN DL
Sbjct 121 DQALLVFLKPPSMEELARRLQARDSES--AEALKSRLERA-EMELSHAGEFDFVVVNDDL 177
Query 649 DKAYQELLRLINKLDTEP 666
+ + I + +P
Sbjct 178 GRTVDAVATRIAEFLPQP 195
>sp|Q0I5L8|KGUA_HISS1 Guanylate kinase OS=Histophilus somni (strain
129Pt) OX=205914 GN=gmk PE=3 SV=2
Length=208
Score = 83.6 bits (205), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 60/185 (32%), Positives = 93/185 (50%), Gaps = 14/185 (8%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEK-DRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R I+ P G++ L L+ ++K D ++ HTTRS R E+ G YHFVS + F
Sbjct 3 RGNLYIISAPSGAGKSSLISALLERDKNDSMTVSISHTTRSPRPGEIDGVHYHFVSHEKF 62
Query 537 EADIAAGKFIEHGE-FEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS--DLKPY 593
E I F+E+ + F N YGTS+ ++ + + +G L + Q + +R D+K
Sbjct 63 EQLILENSFLEYAKVFGGNYYGTSLLNIEKNLAAGIDVFLDIDWQGARQIREKRPDVKS- 121
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNN-GHY--FDTAIVNSDLDK 650
IFI PPS L L G++ + +II K E + HY +D I+N+D D+
Sbjct 122 -IFILPPSISALEKRLIGRGQDSQ-----DIIAKRMEKAADEISHYDEYDYVIINADFDQ 175
Query 651 AYQEL 655
A +L
Sbjct 176 ALVDL 180
>sp|Q8KPQ7|KGUA_SYNE7 Guanylate kinase OS=Synechococcus elongatus
(strain ATCC 33912 / PCC 7942 / FACHB-805) OX=1140 GN=gmk
PE=3 SV=2
Length=183
Score = 82.8 bits (203), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 51/176 (29%), Positives = 88/176 (50%), Gaps = 3/176 (2%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
R ++L GP G+ L + ++++ + F S + TTRS R EV G+ Y+F+SR+ F+
Sbjct 5 RVVVLTGPSGVGKGTLLKAILSQHPEAFLS-ISATTRSPRPGEVDGQHYYFLSREEFQTK 63
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
IA +F+E EF NLYGT V + +N G+ +L + + + +R + + + P
Sbjct 64 IAEQEFLEWAEFAGNLYGTPRSPVIEQVNLGRTVILEIELEGARQVRKTLPSARQVMLLP 123
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
PS E L + + + R +++ E+ FD ++N LD A L
Sbjct 124 PSVEELERRIRERATEDEAAIARRLLQAQTEI--GAAKEFDRCVINDQLDTAITAL 177
>sp|Q2GLF7|KGUA_ANAPZ Guanylate kinase OS=Anaplasma phagocytophilum
(strain HZ) OX=212042 GN=gmk PE=1 SV=1
Length=210
Score = 83.6 bits (205), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 53/171 (31%), Positives = 83/171 (49%), Gaps = 3/171 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++L P CG+ + +L+ K+K+ +V TTR+ R E G+DY+FV R+ F +
Sbjct 9 LVLSSPSGCGKTTVANKLLEKQKNNIVKSVSVTTRAARKGEKEGKDYYFVDREEFLRLCS 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQ-SLKTLRNSDLKPYIIFIAPP 600
G+ IEH E N YG ++ ++ G LL + Q + K + IFI PP
Sbjct 69 NGEIIEHAEVFGNFYGVPRKNLEDNVDKGVSTLLVIDWQGAFKFMEMMREHVVSIFIMPP 128
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
S E LR L G+ E+ E K E ++ +D IVN D+++
Sbjct 129 SMEELRRRLC--GRRADDSEVVEARLKGAAFEISHCEAYDYVIVNEDIEET 177
>sp|Q8EJU6|KGUA_SHEON Guanylate kinase OS=Shewanella oneidensis
(strain MR-1) OX=211586 GN=gmk PE=3 SV=1
Length=207
Score = 83.2 bits (204), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 55/184 (30%), Positives = 84/184 (46%), Gaps = 6/184 (3%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R I+ P G++ L L+ + +V HTTR+ R E+ G+ YHFV+ + F+
Sbjct 4 RGNLFIVSAPSGAGKSSLISALLKDKPADMQVSVSHTTRAPRPGEINGQHYHFVNVEEFK 63
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
A IA F E E N YGTS + + G L + Q + ++ + +FI
Sbjct 64 ALIAQNAFFEWAEVFGNYYGTSRHVIEHTLTQGIDVFLDIDWQGAQQVKAVMPEAIGVFI 123
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQEL 655
PPS++ L L G++ K + + EM HY +D IVN D D A +L
Sbjct 124 LPPSRDELERRLTGRGQDSKDVIDSRMAQAVSEMS----HYKEYDFIIVNDDFDTALADL 179
Query 656 LRLI 659
+I
Sbjct 180 RAII 183
>sp|Q21TP7|KGUA_ALBFT Guanylate kinase OS=Albidiferax ferrireducens
(strain ATCC BAA-621 / DSM 15236 / T118) OX=338969 GN=gmk
PE=3 SV=1
Length=206
Score = 83.2 bits (204), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 53/179 (30%), Positives = 90/179 (50%), Gaps = 3/179 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++ P G++ L + L+ + +V HTTR+ R QE GR+Y FVS Q F+A +
Sbjct 8 FVVAAPSGAGKSSLVKALLELD-SHVQLSVSHTTRAPRGQEKHGREYFFVSEQEFDAMVK 66
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
A F+E ++ YGTS ++ + + G +L + Q ++ IFI PPS
Sbjct 67 ADAFVEWASVHQHRYGTSKRAIEERMAQGADVVLEIDYQGALQIKKLFANAISIFILPPS 126
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
+ LRA L + G++ ++ E+ K +E H FD I+N D+A +L +++
Sbjct 127 WDELRARLERRGEDSA--DVIELRLKNAAIEVAQVHKFDFVIINELFDRALFDLKAIVH 183
>sp|Q5P3M0|KGUA_AROAE Guanylate kinase OS=Aromatoleum aromaticum
(strain EbN1) OX=76114 GN=gmk PE=3 SV=2
Length=204
Score = 83.2 bits (204), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 57/178 (32%), Positives = 86/178 (48%), Gaps = 3/178 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
II+ P G+ L L+ ++ + +V +TTR R E GR+YHFV F A
Sbjct 6 IIITAPSGAGKTTLVSGLLERDP-QVNLSVSYTTREPRPGERDGREYHFVDVATFRALRD 64
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+F+E E N Y TS ++Q I +G+ LL + Q + +R S +FI PPS
Sbjct 65 RGEFLEWAEVHGNYYATSKVWLKQQIATGRDILLEIDWQGAQQVRKSFPDAVGVFILPPS 124
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
E L A L G + +R ++ EM FD I+N+DL A +L+ ++
Sbjct 125 LEELEARLRGRGTDSDDVIMRRLLGARGEMRHVG--EFDYVILNNDLQCALDDLVAVV 180
>sp|Q9D5S7|LRGUK_MOUSE Leucine-rich repeat and guanylate kinase
domain-containing protein OS=Mus musculus OX=10090 GN=Lrguk
PE=1 SV=1
Length=820
Score = 88.6 bits (218), Expect = 7e-17, Method: Compositional matrix adjust.
Identities = 52/180 (29%), Positives = 87/180 (48%), Gaps = 2/180 (1%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+IL GP CG+ EL RL + F HTTR E DYHF+S++ F+ +
Sbjct 417 LILTGPAACGKRELAHRLCRQFSTYFRYGACHTTRPPYFGEGDRVDYHFISQEVFDEMLN 476
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
GKFI + + YG + D++ + G + + + +++L+ S +P I + P
Sbjct 477 MGKFILTFNYGNHNYGLNRDTIEGIARDGLASCIHMELEGVRSLKYSYFEPRYILVVPMD 536
Query 602 QERLRALLAKEGKNPKPEELREI--IEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
+E+ L ++G + E + ++ ++ Q YFD I D+D AYQ+L LI
Sbjct 537 KEKYEGYLRRKGLFSRAEIEIAVSRVDLYVKVNQKYPGYFDAVINADDMDIAYQKLSELI 596
>sp|Q5X3P2|KGUA_LEGPA Guanylate kinase OS=Legionella pneumophila
(strain Paris) OX=297246 GN=gmk PE=3 SV=1
Length=209
Score = 82.8 bits (203), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 59/195 (30%), Positives = 94/195 (48%), Gaps = 9/195 (5%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N I+ P G+ L ++L+ + +V HTTR R E G DY F+ + F
Sbjct 5 NSGNLYIVAAPSGGGKTSLVKKLIEMVGE-IEVSVSHTTRPMRPGEKEGVDYFFIDEEQF 63
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ + G FIEH + + YGTS+ + + + G +L + Q + +R+S +F
Sbjct 64 ISMVNEGAFIEHAKVFNHWYGTSVAQINKRLQFGIDVVLDIDWQGAEQIRHSYPDAVSVF 123
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQE 654
I PPS + L+ L N + ++ I E+ + + GHY FD IVN D +KA E
Sbjct 124 IIPPSLDTLKERLM----NRRQDKDNVISERMTKAQDELGHYPEFDYLIVNDDFEKAAME 179
Query 655 LLRLI--NKLDTEPQ 667
L ++ N+L E Q
Sbjct 180 LQSIVIANRLRIEKQ 194
>sp|Q3IJH8|KGUA_PSET1 Guanylate kinase OS=Pseudoalteromonas translucida
(strain TAC 125) OX=326442 GN=gmk PE=3 SV=1
Length=206
Score = 82.8 bits (203), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 58/182 (32%), Positives = 83/182 (46%), Gaps = 9/182 (5%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R IL P G++ L L+ K D S V HTTR++R E G YHFVS F
Sbjct 4 TRGNLFILSAPSGAGKSSLINALLKKHTDMKVS-VSHTTRAKRPGEENGVHYHFVSTDEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+A I F E + N YGTS ++ +++G L + Q + +R IF
Sbjct 63 KALITKDDFFEWAQVFDNYYGTSKQAIESQLDAGIDVFLDIDWQGAQQVRKIMPSVQTIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIE-KTREMEQNNGHY--FDTAIVNSDLDKAYQ 653
I PPS+ L L G++ + EII + + + HY +D IVN D D A
Sbjct 123 ILPPSKAELEQRLNNRGQDSQ-----EIIAGRMAQAQSETSHYNEYDFVIVNDDFDTALT 177
Query 654 EL 655
++
Sbjct 178 DI 179
>sp|Q0VT94|KGUA_ALCBS Guanylate kinase OS=Alcanivorax borkumensis
(strain ATCC 700651 / DSM 11573 / NCIMB 13689 / SK2) OX=393595
GN=gmk PE=3 SV=1
Length=207
Score = 82.8 bits (203), Expect = 1e-16, Method: Composition-based stats.
Identities = 58/182 (32%), Positives = 86/182 (47%), Gaps = 7/182 (4%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A++ I+ P G+ L L++K + ++ HTTR+ R E G +YHF R
Sbjct 2 ADKGTLYIISAPSGAGKTSLVAALVDKLA-QVRISISHTTRAMRPGEKDGVNYHFTDRDC 60
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F + G+F+EH + NLYGTS D V Q + +G +L + Q +R I
Sbjct 61 FVRQVEQGRFLEHAQVFGNLYGTSADWVAQTLRTGDDVILEIDWQGATQIRKQLPDSVSI 120
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQ 653
FI PPS E L L G+ E + I ++ ++ HY FD +VN D +A
Sbjct 121 FILPPSLEALAGRL--RGRETDDETV--IQQRLDGAQEEMSHYGEFDYLVVNDDFQRALY 176
Query 654 EL 655
EL
Sbjct 177 EL 178
>sp|Q30PL1|KGUA_SULDN Guanylate kinase OS=Sulfurimonas denitrificans
(strain ATCC 33889 / DSM 1251) OX=326298 GN=gmk PE=3
SV=1
Length=206
Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 58/180 (32%), Positives = 94/180 (52%), Gaps = 7/180 (4%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++L GP G++ L + +++ + + S + TTR R+ EV G YHFVS F+ DI
Sbjct 9 LVLSGPSGAGKSSLIKEVIDDIGECYFS-ISTTTRPIREGEVDGVHYHFVSESEFKKDIE 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN--SDLKPYIIFIAP 599
F+E+ N YGTSI V++ + SGK+ + + Q T+ N D+ +FI+P
Sbjct 68 DEFFLEYAVVHSNYYGTSIKPVKKALKSGKLVIFDIDVQGNATIINRLGDITTS-VFISP 126
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
P+ L+ L + K R I REM++ + +D IVN +L +A + LR+I
Sbjct 127 PTLSELKKRLEARSTDTKDVIERRIEMAKREMQRVSE--YDFLIVNDNLQEA-AKTLRII 183
>sp|Q5QYH9|KGUA_IDILO Guanylate kinase OS=Idiomarina loihiensis
(strain ATCC BAA-735 / DSM 15497 / L2-TR) OX=283942 GN=gmk
PE=3 SV=1
Length=210
Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 57/179 (32%), Positives = 87/179 (49%), Gaps = 3/179 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDR-FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L + L+ K D+ +V TTR+ R EV G YHF+S + FE I
Sbjct 11 FIIAAPSGAGKSSLIRALLEKHPDQSMQVSVSSTTRAPRPGEVQGVHYHFLSTEEFEQRI 70
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
AG+F E N YGTS V ++ GK L + Q + +R + +FI PP
Sbjct 71 DAGEFYEWARVFGNYYGTSRKVVESLLAEGKDVFLDIDWQGAQQVREHHPEVRSVFIVPP 130
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
S E L L G++ E + E + K + E ++ H FD +VN D + + L ++
Sbjct 131 SLEILEERLRVRGQDSD-EVIAERMAKA-QAEMSHYHEFDYLLVNDDFNNSLASLEHIV 187
>sp|Q12IL8|KGUA_SHEDO Guanylate kinase OS=Shewanella denitrificans
(strain OS217 / ATCC BAA-1090 / DSM 15013) OX=318161 GN=gmk
PE=3 SV=1
Length=207
Score = 82.4 bits (202), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 53/182 (29%), Positives = 83/182 (46%), Gaps = 2/182 (1%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R I+ P G++ L L+ + +V HTTR+ R EV G+ YHFVS + F+
Sbjct 4 RGNLFIVSAPSGAGKSSLITALLKDKPQDMQVSVSHTTRAPRPGEVDGQHYHFVSVEQFK 63
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
A IA F E E N YGTS + ++ G L + Q + ++ + +FI
Sbjct 64 ALIAENAFFESAEVFGNFYGTSRQVIENTLSLGIDVFLDIDWQGAQQVKKIMPEAIGVFI 123
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS+ L L G++ + + EM N +D I+N D ++A +L
Sbjct 124 LPPSKAELERRLTGRGQDSSDVIAARMAQAVSEMSHYN--EYDFVIINDDFEQALADLKS 181
Query 658 LI 659
+I
Sbjct 182 II 183
>sp|Q7VIA1|KGUA_HELHP Guanylate kinase OS=Helicobacter hepaticus
(strain ATCC 51449 / 3B1) OX=235279 GN=gmk PE=3 SV=1
Length=200
Score = 82.4 bits (202), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 56/188 (30%), Positives = 95/188 (51%), Gaps = 16/188 (9%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+I+ GP CG++ L + L+ + + S + TTR R+ E G YHFVS++ F DI
Sbjct 7 LIISGPSGCGKSTLTKSLIESIPNVYFS-ISTTTRPMREGETDGVHYHFVSKEHFLQDIH 65
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI------I 595
F+E E N YGTS+ V+Q + KI L + Q + +K Y +
Sbjct 66 NNVFLEWAEVHTNFYGTSLKPVQQALEQDKIVLFDVDVQG-----HHSIKEYFGDFAKSV 120
Query 596 FIAPPSQERLRA-LLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
FI +++ LR L++++ + + E R +I+ EM+ + H FD I+N D+ A +
Sbjct 121 FITTKNKDILRERLISRQTDDLQTIEFR-LIQAHNEMQ--HIHNFDYLIINDDITTAKEA 177
Query 655 LLRLINKL 662
++ + L
Sbjct 178 MVAIARSL 185
>sp|Q7VRJ7|KGUA_BLOFL Guanylate kinase OS=Blochmannia floridanus
OX=203907 GN=gmk PE=3 SV=1
Length=210
Score = 82.4 bits (202), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 51/172 (30%), Positives = 88/172 (51%), Gaps = 7/172 (4%)
Query 483 ILIGPQNCGQNELRQRLM-NKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+ P G++ L L N + ++ +TTR +R EV G+DY+F+S + F+ I
Sbjct 10 IISAPSGAGKSTLINALQKNDSILQIKLSISYTTRKKRPGEVHGKDYYFISIEEFQNMIN 69
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
F+E+ + + YGT +S++ ++NSG +L++ Q + +RN L Y IFI PPS
Sbjct 70 QNMFLEYAKVFNHYYGTEKNSIKLMLNSGVHVILNIDWQGMNQIRNKKLDFYTIFILPPS 129
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKA 651
Q+ L L G + + I ++ ++ H +D I+N D + A
Sbjct 130 QKELEKRLRFRGLDTD----QVIFDRMKQAMNEISHCKEYDYIIINDDFNIA 177
>sp|Q47UB3|KGUA_COLP3 Guanylate kinase OS=Colwellia psychrerythraea
(strain 34H / ATCC BAA-681) OX=167879 GN=gmk PE=3 SV=1
Length=218
Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 57/185 (31%), Positives = 87/185 (47%), Gaps = 10/185 (5%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASA----VPHTTRSRRDQEVAGRDYHFVSRQAFE 537
IL P G++ L L+ + A A + HTTR R E G YHFVS + F+
Sbjct 8 FILSAPSGAGKSSLINALLKPDNQASARAMQVSISHTTRDARPGENNGEHYHFVSVEEFK 67
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I+ F E+ E N YGTS ++ ++ G L + Q + +R IFI
Sbjct 68 KQISLNAFYEYAEVFGNYYGTSEAAIDAQLSQGIDVFLDIDWQGAQQVRMKKPGVTTIFI 127
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQEL 655
+PPS+E L + L G+ +E+ I + + + HY FD IVN D ++A +L
Sbjct 128 SPPSKEELESRL--RGRGQDSDEV--IASRMAQAQAECSHYNEFDYVIVNDDFEQALLDL 183
Query 656 LRLIN 660
++N
Sbjct 184 TTIVN 188
>sp|Q8Z2H9|KGUA_SALTI Guanylate kinase OS=Salmonella typhi OX=90370
GN=gmk PE=3 SV=1
Length=207
Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 59/181 (33%), Positives = 87/181 (48%), Gaps = 9/181 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ + D S V HTTR+ R EV G Y FV+ F+ I
Sbjct 8 IVSAPSGAGKSSLIQALLKTQPLYDTQVS-VSHTTRAPRPGEVHGEHYFFVNHDEFKTMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
F+EH E N YGTS +++ QV+ +G L + Q + +R + IFI PP
Sbjct 67 GREAFLEHAEVFGNYYGTSRETIEQVLATGVDVFLDIDWQGAQQIREKMPQARSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLRL 658
S+ L L G++ + + + + EM HY +D IVN D D A +L +
Sbjct 127 SKIELDRRLRGRGQDSEEVIAKRMAQAVAEM----SHYAEYDYLIVNDDFDTALSDLKTI 182
Query 659 I 659
I
Sbjct 183 I 183
>sp|Q5PC40|KGUA_SALPA Guanylate kinase OS=Salmonella paratyphi
A (strain ATCC 9150 / SARB42) OX=295319 GN=gmk PE=3 SV=1
Length=207
Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 59/181 (33%), Positives = 87/181 (48%), Gaps = 9/181 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ + D S V HTTR+ R EV G Y FV+ F+ I
Sbjct 8 IVSAPSGAGKSSLIQALLKTQPLYDTQVS-VSHTTRAPRPGEVHGEHYFFVNHDEFKTMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
F+EH E N YGTS +++ QV+ +G L + Q + +R + IFI PP
Sbjct 67 GREAFLEHAEVFGNYYGTSRETIEQVLATGVDVFLDIDWQGAQQIREKMPQARSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLRL 658
S+ L L G++ + + + + EM HY +D IVN D D A +L +
Sbjct 127 SKIELDRRLRGRGQDSEEVIAKRMAQAVAEM----SHYAEYDYLIVNDDFDTALSDLKTI 182
Query 659 I 659
I
Sbjct 183 I 183
>sp|Q83EL7|KGUA_COXBU Guanylate kinase OS=Coxiella burnetii (strain
RSA 493 / Nine Mile phase I) OX=227377 GN=gmk PE=1 SV=1
Length=206
Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 57/187 (30%), Positives = 88/187 (47%), Gaps = 9/187 (5%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N+ I+ P G+ L R + K ++ HTTR +R + G DY F+ F
Sbjct 2 NKANLFIISAPSGAGKTSL-VRALVKALAEIKISISHTTRPKRPGDQEGVDYFFIDETRF 60
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+A + G F+EH + YGT D V + + +G+ LL + Q + +R IF
Sbjct 61 QAMVKEGAFLEHATIYERHYGTEKDWVLRQLKAGRDVLLEIDWQGARQIRELFPPALSIF 120
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNN-GHY--FDTAIVNSDLDKAYQ 653
I PPS E LR L K ++ IIE+ + + HY FD +VN + D+A Q
Sbjct 121 ILPPSIEALRERLIKRRQDDTA-----IIEQRLALAREEMAHYKEFDYLVVNDNFDQAVQ 175
Query 654 ELLRLIN 660
L+ +I+
Sbjct 176 NLIHIIS 182
>sp|Q5WFK3|KGUA_SHOC1 Guanylate kinase OS=Shouchella clausii (strain
KSM-K16) OX=66692 GN=gmk PE=3 SV=1
Length=205
Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 47/132 (36%), Positives = 69/132 (52%), Gaps = 1/132 (1%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ + L N + +V TTR R+ E G +Y F +R+ FE I
Sbjct 9 IVLSGPAGVGKGTVCGALRN-QNTAIEYSVSATTRKPREGEKHGVNYFFKTREQFEQMIE 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
GK +E E+ N YGT ID V++ IN+GK +L + Q + +R + IF+APPS
Sbjct 68 DGKLLEWAEYVGNYYGTPIDYVQETINAGKDIILEIEVQGAQKVRTVFPEGVFIFLAPPS 127
Query 602 QERLRALLAKEG 613
+ LR + G
Sbjct 128 LKELRDRIVGRG 139
>sp|Q3AQL3|KGUA_CHLCH Guanylate kinase OS=Chlorobium chlorochromatii
(strain CaD3) OX=340177 GN=gmk PE=3 SV=1
Length=190
Score = 81.6 bits (200), Expect = 2e-16, Method: Composition-based stats.
Identities = 56/175 (32%), Positives = 87/175 (50%), Gaps = 4/175 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+ P G+ + ++ + + + +V TTR +R+ E G +Y+F+ + FE I
Sbjct 10 IVFSAPSGAGKTTIATMVLQRIAN-LSFSVSATTRKQREGEQDGVNYYFLDKATFEKKIE 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN-SDLKPYIIFIAPP 600
G FIEH F N YGT +D+ V+ SGK LL + + +R + +IFI PP
Sbjct 69 QGGFIEHEFFFGNYYGTLLDATESVLASGKNLLLDVDVKGALNVRKLFGERSLLIFIQPP 128
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
S E L L G L+E +E+ R E + FDT IVN++L A ++
Sbjct 129 SMEVLIERLQGRGSEDDA-ALQERLERAR-FEMSFADQFDTIIVNNNLTAAVDDV 181
>sp|Q9X6M5|KGUA_SALTY Guanylate kinase OS=Salmonella typhimurium
(strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=gmk PE=3
SV=1
Length=207
Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 59/181 (33%), Positives = 87/181 (48%), Gaps = 9/181 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ + D S V HTTR+ R EV G Y FV+ F+ I
Sbjct 8 IVSAPSGAGKSSLIQALLKTQPLYDTQVS-VSHTTRAPRPGEVHGEHYFFVNHDEFKTMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
F+EH E N YGTS +++ QV+ +G L + Q + +R + IFI PP
Sbjct 67 GREAFLEHAEVFGNYYGTSRETIEQVLATGVDVFLDIDWQGAQQIREKMPQARSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLRL 658
S+ L L G++ + + + + EM HY +D IVN D D A +L +
Sbjct 127 SKIELDRRLRGRGQDSEEVIAKRMAQAVAEM----SHYAEYDYLIVNDDFDTALSDLKTI 182
Query 659 I 659
I
Sbjct 183 I 183
>sp|Q5ZTZ8|KGUA_LEGPH Guanylate kinase OS=Legionella pneumophila
subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 /
DSM 7513) OX=272624 GN=gmk PE=3 SV=1
Length=209
Score = 82.0 bits (201), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 58/195 (30%), Positives = 94/195 (48%), Gaps = 9/195 (5%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N I+ P G+ L ++L+ + +V HTTR R E G DY F+ + F
Sbjct 5 NSGNLYIVAAPSGGGKTSLVKKLIEMVGE-IEVSVSHTTRPMRPGEKEGVDYFFIDEKQF 63
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ + G FIEH + + YGTS+ + + + G +L + Q + +R++ +F
Sbjct 64 ISMVNEGAFIEHAKVFNHWYGTSVAQINKRLQFGIDVVLDIDWQGAEQIRHAYPDAVSVF 123
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQE 654
I PPS + L+ L N + ++ I E+ + + GHY FD IVN D +KA E
Sbjct 124 IIPPSLDALKERLM----NRRQDKDHVISERMTKAQDELGHYPEFDYLIVNDDFEKAAME 179
Query 655 LLRLI--NKLDTEPQ 667
L ++ N+L E Q
Sbjct 180 LQSIVIANRLRIEKQ 194
>sp|Q5WV30|KGUA_LEGPL Guanylate kinase OS=Legionella pneumophila
(strain Lens) OX=297245 GN=gmk PE=3 SV=1
Length=209
Score = 81.6 bits (200), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 58/195 (30%), Positives = 94/195 (48%), Gaps = 9/195 (5%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N I+ P G+ L ++L+ + +V HTTR R E G DY F+ + F
Sbjct 5 NSGNLYIVAAPSGGGKTSLVKKLIEMVGE-IEVSVSHTTRPMRPGEKEGVDYFFIDEEQF 63
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ + G FIEH + + YGTS+ + + + G +L + Q + +R++ +F
Sbjct 64 ISMVNEGAFIEHAKVFNHWYGTSVAQINKRLQFGIDVVLDIDWQGAEQIRHAYPDAVSVF 123
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQE 654
I PPS + L+ L N + ++ I E+ + + GHY FD IVN D +KA E
Sbjct 124 IIPPSLDALKERLM----NRRQDKDNVISERMTKAQDELGHYPEFDYLIVNDDFEKAAME 179
Query 655 LLRLI--NKLDTEPQ 667
L ++ N+L E Q
Sbjct 180 LQSIVIANRLRIEKQ 194
>sp|Q088T7|KGUA_SHEFN Guanylate kinase OS=Shewanella frigidimarina
(strain NCIMB 400) OX=318167 GN=gmk PE=3 SV=1
Length=207
Score = 81.6 bits (200), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 55/186 (30%), Positives = 85/186 (46%), Gaps = 6/186 (3%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ P G++ L L+ + +V HTTR R EV G+ YHF++ +
Sbjct 2 STRGNLFIVSAPSGAGKSSLISTLLKDKPSDKQVSVSHTTRKPRPGEVDGQHYHFITVEQ 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F+A IA FIE E N YGTS + Q ++ G L + Q + ++ +
Sbjct 62 FKALIAQNAFIEWAEVFGNFYGTSKLVIEQTLDKGIDVFLDIDWQGAEQVKKLMETAIGV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQ 653
FI PPS+ L L G++ + + + EM HY ++ IVN D D A
Sbjct 122 FILPPSKAELERRLTGRGQDSQQVIDSRMAQAVSEMS----HYAQYEFIIVNDDFDNALA 177
Query 654 ELLRLI 659
+L +I
Sbjct 178 DLSAII 183
>sp|Q6MDG3|KGUA_PARUW Guanylate kinase OS=Protochlamydia amoebophila
(strain UWE25) OX=264201 GN=gmk PE=3 SV=1
Length=197
Score = 81.3 bits (199), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 61/177 (34%), Positives = 89/177 (50%), Gaps = 10/177 (6%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+ P G+ L L+ +E +++ +TTR+ R EV G+DY+F++ FEA IA
Sbjct 13 FIVSAPAGTGKTTLVN-LLVQEFPTVIASISYTTRAPRLGEVNGKDYYFITESEFEAKIA 71
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
A F+E+ + YGTS + V G +L + TQ L+ + IFI PPS
Sbjct 72 AADFLEYVKLYDTYYGTSREWVEIQRQLGLHVILVIDTQGALQLQKL-CEATFIFIRPPS 130
Query 602 QERLRALLAKEGKNPKPEELREIIEK---TREMEQNNGHYFDTAIVNSDLDKAYQEL 655
+ L+ L N + E L E+IEK E E Y+D I+N DL +AYQ L
Sbjct 131 LDELKNRLI----NRQTESL-EMIEKRLACAERELEAAQYYDYEIINDDLQEAYQVL 182
>sp|Q21EC9|KGUA_SACD2 Guanylate kinase OS=Saccharophagus degradans
(strain 2-40 / ATCC 43961 / DSM 17024) OX=203122 GN=gmk
PE=3 SV=2
Length=205
Score = 81.6 bits (200), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 57/186 (31%), Positives = 84/186 (45%), Gaps = 9/186 (5%)
Query 486 GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKF 545
P G+ L L++ + S V HTTR++R E G +YHFVS + F + F
Sbjct 12 APSGAGKTSLVSALIDTTSNIMVS-VSHTTRAKRPGEQEGVNYHFVSHEQFATMVENNAF 70
Query 546 IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERL 605
+EH + N YGTS V + G +L + Q + +R +FI PPS+E L
Sbjct 71 LEHAQVFTNFYGTSKQWVEDTLAKGIDVILEIDWQGAQQVRKLIPAAKSVFILPPSRECL 130
Query 606 RALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDT--AIVNSDLDKAYQELLRLI--NK 661
R L G++ + I + E + HY + IVN D D A E ++ N+
Sbjct 131 RERLTGRGQDDES----VIDARMAEAKSEISHYVEAQYLIVNDDFDTALTEFRSIVVANR 186
Query 662 LDTEPQ 667
L E Q
Sbjct 187 LALEKQ 192
>sp|Q7VDB6|KGUA_PROMA Guanylate kinase OS=Prochlorococcus marinus
(strain SARG / CCMP1375 / SS120) OX=167539 GN=gmk PE=3 SV=1
Length=184
Score = 80.9 bits (198), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 52/178 (29%), Positives = 90/178 (51%), Gaps = 3/178 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I++ GP G+ L ++L+ + + + S + TTR+ R+ E+ G+DY F++++ F +
Sbjct 8 IVITGPSGVGKGTLVKKLLLENPEIWLS-ISATTRTPREGEINGKDYFFLNKKEFIDLVD 66
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
F+E EF N YGT ++ I+ GK LL + + +R + + + IFIAPPS
Sbjct 67 KEGFLEWAEFAGNFYGTPRAQAQEKISVGKKVLLEIELDGARQVRKTFPEGFQIFIAPPS 126
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
E L + G + + + E+ N FD ++N LD A E+ +LI
Sbjct 127 FEELEKRIRTRGTDSELAIQSRLNRAKEELLAKN--EFDAIVINDQLDIALLEIKKLI 182
>sp|Q9A7N9|KGUA_CAUVC Guanylate kinase OS=Caulobacter vibrioides
(strain ATCC 19089 / CB15) OX=190650 GN=gmk PE=3 SV=1
Length=213
Score = 81.6 bits (200), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 53/193 (27%), Positives = 94/193 (49%), Gaps = 5/193 (3%)
Query 469 MSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDY 528
M+ H P +R ++++ P G+ L +RL++ D S + TTR R E GRDY
Sbjct 1 MNKSHHP-HRGLLLMVVAPSGVGKTSLTRRLVSDHGDLHLS-ISATTRDPRPGEHDGRDY 58
Query 529 HFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQ-SLKTLRN 587
HFVSR F+ +A F+E E N YG+ + ++ G+ L + Q ++K +
Sbjct 59 HFVSRDKFQGMLAEDAFLEWAEVYGNFYGSPKAPIMDALSRGESVLFDIDFQGAMKVHKQ 118
Query 588 SDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD 647
+ +++I PPS + L ++ + E + + + ++ E FD I+N D
Sbjct 119 AGADSVLVYILPPSLAEMSRRLHTRSQDSE-EVIHRRLSRAKD-EVAAWEQFDYVILNDD 176
Query 648 LDKAYQELLRLIN 660
D+AY +L + +
Sbjct 177 FDRAYADLAHIYH 189
>sp|Q8DVK6|KGUA_STRMU Guanylate kinase OS=Streptococcus mutans
serotype c (strain ATCC 700610 / UA159) OX=210007 GN=gmk PE=3
SV=1
Length=210
Score = 81.3 bits (199), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 51/184 (28%), Positives = 89/184 (48%), Gaps = 2/184 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R E+ G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHQFEYSVSMTTRPQRLGEIDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q ++ I
Sbjct 62 FEELIKQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKQKVPDGVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP L+ L G + + E + + IE+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLAELKDRLVGRGTDSQ-EVIAQRIERAKE-EIALMREYDYAVVNDEVKLAAERV 179
Query 656 LRLI 659
+I
Sbjct 180 KHII 183
>sp|Q87TA9|KGUA_VIBPA Guanylate kinase OS=Vibrio parahaemolyticus
serotype O3:K6 (strain RIMD 2210633) OX=223926 GN=gmk PE=3
SV=1
Length=207
Score = 81.3 bits (199), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 58/182 (32%), Positives = 86/182 (47%), Gaps = 12/182 (7%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDR-FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+ P G++ L ++ + +V HTTR+ R E G YHFV+++ FE IA
Sbjct 8 IVSAPSGAGKSSLISAMLERNPTYAMKVSVSHTTRNMRPGEEDGVHYHFVAKEEFETLIA 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G F+E+ E N YGTS + + + G L + Q + +R K IFI PPS
Sbjct 68 KGDFLEYAEVFGNYYGTSRVWIEETLEKGIDVFLDIDWQGARQIREQMPKAKSIFILPPS 127
Query 602 QERLRALLAKEGKNPKPEELREIIEK-TREMEQNNGHY--FDTAIVNSDLDKA---YQEL 655
L L N + ++ E+I K E + HY +D IVN D D A ++ +
Sbjct 128 NGELERRL-----NTRGQDSAEVIAKRMAEAKSEISHYSEYDYVIVNDDFDTALMDFKAI 182
Query 656 LR 657
LR
Sbjct 183 LR 184
>sp|Q3K4L8|KGUA_PSEPF Guanylate kinase OS=Pseudomonas fluorescens
(strain Pf0-1) OX=205922 GN=gmk PE=3 SV=1
Length=206
Score = 81.3 bits (199), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 56/176 (32%), Positives = 85/176 (48%), Gaps = 9/176 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I+ P G++ L + L + D ++ HTTR+ R EV G +YHFV+R+ F
Sbjct 10 IISAPSGAGKSSLVKALTDTNPD-IRVSISHTTRAMRPGEVDGVNYHFVTREEFVKMGEH 68
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
G F+E E N YGTS ++Q ++ G +L + Q + +R + IFI PPS
Sbjct 69 GDFLERAEVFGNFYGTSQSRLQQTLDEGHDLILEIDWQGAEQVRKLMPQARSIFILPPSL 128
Query 603 ERLRALLAKEGKNPKPEELREIIE-KTREMEQNNGHY--FDTAIVNSDLDKAYQEL 655
+ L L G++ EII+ + RE HY +D I+N D A +L
Sbjct 129 QALHQRLTNRGQDSD-----EIIDGRMREAVSEMSHYVEYDYLIINDDFAHALDDL 179
>sp|Q4FQY7|KGUA_PSYA2 Guanylate kinase OS=Psychrobacter arcticus
(strain DSM 17307 / VKM B-2377 / 273-4) OX=259536 GN=gmk
PE=3 SV=1
Length=208
Score = 81.3 bits (199), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 54/178 (30%), Positives = 81/178 (46%), Gaps = 3/178 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+ G+ L ++L+ D +V HTTR R E+ G YHF F I+
Sbjct 6 FIITAASGTGKTSLVKQLLATTND-LTVSVSHTTRDPRPGEIDGHHYHFTDVDNFVTAIS 64
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+F+EH E N YGTS SVR +++G +L + Q ++ +IFI PPS
Sbjct 65 ESQFLEHAEVFGNYYGTSEQSVRAQLDAGVDVILEIDWQGALQVKKIFTDAIMIFILPPS 124
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
LR L+ G++ + + EM Q FD I+N + + A EL +I
Sbjct 125 IATLRQRLSTRGQDSMEVIEQRLAGAVNEMAQYIN--FDYVIINDNFEVALTELKAII 180
>sp|Q0HZX1|KGUA_SHESR Guanylate kinase OS=Shewanella sp. (strain
MR-7) OX=60481 GN=gmk PE=3 SV=2
Length=207
Score = 80.9 bits (198), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 54/184 (29%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R I+ P G++ L L+ + +V HTTR+ R EV G+ YHFV+ + F+
Sbjct 4 RGNLFIVSAPSGAGKSSLISALLKDKPADMQVSVSHTTRAPRPGEVNGQHYHFVNVEEFK 63
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
A I F E E N YGTS + + G L + Q + ++ + +FI
Sbjct 64 ALIEQNAFFEWAEVFGNYYGTSRHVIEHTLTQGIDVFLDIDWQGAQQVKAVMPEAIGVFI 123
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQEL 655
PPS++ L L G++ + + + EM HY +D IVN D D A +L
Sbjct 124 LPPSRDELERRLTGRGQDSQEVIASRMAQAVSEMS----HYKEYDFIIVNDDFDTALADL 179
Query 656 LRLI 659
+I
Sbjct 180 RAII 183
>sp|Q57I92|KGUA_SALCH Guanylate kinase OS=Salmonella choleraesuis
(strain SC-B67) OX=321314 GN=gmk PE=3 SV=2
Length=207
Score = 80.9 bits (198), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 59/181 (33%), Positives = 86/181 (48%), Gaps = 9/181 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ + D S V HTTR+ R EV G Y FV+ F+ I
Sbjct 8 IVSAPSGAGKSSLIQALLKTQPLYDTQVS-VSHTTRAPRPGEVHGEHYFFVNHDEFKTMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
F+EH E N YGTS ++ QV+ +G L + Q + +R + IFI PP
Sbjct 67 GREAFLEHAEVFGNYYGTSRETTEQVLATGVDVFLDIDWQGAQQIREKMPQARSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLRL 658
S+ L L G++ + + + + EM HY +D IVN D D A +L +
Sbjct 127 SKIELDRRLRGRGQDSEEVIAKRMAQAVAEM----SHYAEYDYLIVNDDFDTALSDLKTI 182
Query 659 I 659
I
Sbjct 183 I 183
>sp|Q1Q973|KGUA_PSYCK Guanylate kinase OS=Psychrobacter cryohalolentis
(strain ATCC BAA-1226 / DSM 17306 / VKM B-2378 / K5)
OX=335284 GN=gmk PE=3 SV=1
Length=208
Score = 80.9 bits (198), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 54/178 (30%), Positives = 80/178 (45%), Gaps = 3/178 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+ G+ L ++L+ D +V HTTR R E+ G YHF F I+
Sbjct 6 FIITAASGTGKTSLVKQLLATTND-LTVSVSHTTREPRPGEIDGHHYHFTDVNKFVTAIS 64
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+F+EH E N YGTS SVR +++G +L + Q ++ +IFI PPS
Sbjct 65 ESQFLEHAEVFGNYYGTSEQSVRAQLDAGVDVILEIDWQGALQVKKIFTDAIMIFILPPS 124
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
LR L+ G++ + + EM Q FD I+N + A EL +I
Sbjct 125 IATLRQRLSTRGQDSMEVIEQRLAGAVNEMAQYVN--FDYVIINDSFEVALTELKAII 180
>sp|Q4FMR1|KGUA_PELUB Guanylate kinase OS=Pelagibacter ubique
(strain HTCC1062) OX=335992 GN=gmk PE=3 SV=1
Length=210
Score = 80.9 bits (198), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 56/183 (31%), Positives = 99/183 (54%), Gaps = 10/183 (5%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+IL P G+ L +L++K K+ F ++ HTTR R E+A +DY+FV FE I
Sbjct 10 VILSSPSGAGKTTL-VKLLSKNKN-FHISISHTTRKPRLNEIADKDYYFVDHDKFENLIK 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII--FIAP 599
+F+E+ + +LYGT+ V + + G+ + + Q ++N L +I FI P
Sbjct 68 NEEFLEYAKVFNHLYGTTRTPVIEKLEKGENVIFDIDWQGADQIKNKKLNYKLITFFILP 127
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLR 657
PS+E L L+ ++ K + + E E+ +E ++ H+ +D I+N DL++ Y ++
Sbjct 128 PSKEILFERLS--NRDMKDKLIVE--ERMKEFSRDVLHWINYDYVIINDDLEECYSKISS 183
Query 658 LIN 660
LI+
Sbjct 184 LID 186
>sp|Q8ER28|KGUA_OCEIH Guanylate kinase OS=Oceanobacillus iheyensis
(strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954
/ HTE831) OX=221109 GN=gmk PE=3 SV=1
Length=206
Score = 80.9 bits (198), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 48/178 (27%), Positives = 88/178 (49%), Gaps = 3/178 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
IL GP G+ +R++L +E D ++ TTR RR EV G DY + +++ FE I
Sbjct 9 FILSGPSGVGKGTVRKKLFEEETD-LQYSISMTTRDRRPGEVDGVDYFYKTKEEFEQLIK 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+ +E+ ++ N YGT + V + + +G+ L + Q ++ + + IF+ PPS
Sbjct 68 DGQLLEYAQYVNNYYGTPRNYVEETLENGQDVFLEIEVQGALQVKENFPEGVFIFLFPPS 127
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
+ L+ + G + L + E E+E + +D +VN + A ++ +I
Sbjct 128 LDELKNRIVSRGTESQELVLNRLKEARNEIEMMDA--YDYVVVNDKVQHAVDKVKTII 183
>sp|Q2JQ59|KGUA_SYNJB Guanylate kinase OS=Synechococcus sp. (strain
JA-2-3B'a(2-13)) OX=321332 GN=gmk PE=3 SV=1
Length=221
Score = 81.3 bits (199), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 57/185 (31%), Positives = 93/185 (50%), Gaps = 3/185 (2%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
P R R ++L GP G+ L +L + + + S V TTR R E G +Y+F SR+
Sbjct 28 PTPRGRLVVLTGPSGVGKGTLVNQLRQRHPELYLS-VSVTTRPPRPSEQEGVNYYFRSRE 86
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
F I A + +E ++ N YGT + V Q +N G+ LL + + +R
Sbjct 87 EFLNLIEANELLEWAQYAGNFYGTPREIVFQKLNQGQDVLLEIELAGARQVRQQYPDAIR 146
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IF+ PPS E L + + G++ + R + + +E++ + FD IVN +L++A QE
Sbjct 147 IFLCPPSLEELERRIRERGQDSEASIERRLEQARKELDAQDE--FDYVIVNDNLEQALQE 204
Query 655 LLRLI 659
L L+
Sbjct 205 LEALL 209
>sp|Q31UQ6|KGUA_SHIBS Guanylate kinase OS=Shigella boydii serotype
4 (strain Sb227) OX=300268 GN=gmk PE=3 SV=1
Length=207
Score = 80.9 bits (198), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 59/181 (33%), Positives = 86/181 (48%), Gaps = 9/181 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ + D S V HTTR R EV G Y FV+ F+ I
Sbjct 8 IVSAPSGAGKSSLIQALLKTQPLYDTQVS-VSHTTRQPRPGEVHGEHYFFVNHDEFKEMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
+ F+EH E N YGTS +++ QV+ +G L + Q + +R IFI PP
Sbjct 67 SRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLRL 658
S+ L L G++ + + + + EM HY +D IVN D D A +L +
Sbjct 127 SKIELDRRLRGRGQDSEEVIAKRMAQAVAEM----SHYDEYDYLIVNDDFDTALTDLKTI 182
Query 659 I 659
I
Sbjct 183 I 183
>sp|Q3AC14|KGUA_CARHZ Guanylate kinase OS=Carboxydothermus hydrogenoformans
(strain ATCC BAA-161 / DSM 6008 / Z-2901) OX=246194
GN=gmk PE=3 SV=1
Length=204
Score = 80.9 bits (198), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 52/177 (29%), Positives = 88/177 (50%), Gaps = 9/177 (5%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ GP G+ + Q + + + F S + TTR +R E+ G Y+F+ RQ FE IA
Sbjct 7 VVVSGPSGAGKGTICQEIRKRNPNLFYS-ISATTREKRVGEIDGVHYYFIDRQQFEKMIA 65
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+F+E + N YGT V + + G+ +L + + + ++ + + +FI PPS
Sbjct 66 NDEFLEWADVYGNYYGTPKKPVFEALARGQDVILEIDIKGARQVKKTYPEGVFVFILPPS 125
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREM---EQNNGHYFDTAIVNSDLDKAYQEL 655
L L K G + + EII K +M E N ++D I+N DL+ A +L
Sbjct 126 ISILEERLRKRGTDKE-----EIIVKRMQMAWEEIANCDWYDYLILNDDLETAVNDL 177
>sp|Q329K8|KGUA_SHIDS Guanylate kinase OS=Shigella dysenteriae
serotype 1 (strain Sd197) OX=300267 GN=gmk PE=3 SV=1
Length=207
Score = 80.9 bits (198), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 59/181 (33%), Positives = 86/181 (48%), Gaps = 9/181 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ + D S V HTTR R EV G Y FV+ F+ I
Sbjct 8 IVSAPSGAGKSSLIQALLKTQPLYDTQVS-VSHTTRQPRPGEVHGEHYFFVNHDEFKEMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
+ F+EH E N YGTS +++ QV+ +G L + Q + +R IFI PP
Sbjct 67 SRDAFLEHAEVFDNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLRL 658
S+ L L G++ + + + + EM HY +D IVN D D A +L +
Sbjct 127 SKIELDRRLRGRGQDSEEVIAKRMAQAVAEM----SHYAEYDYLIVNDDFDTALTDLKTI 182
Query 659 I 659
I
Sbjct 183 I 183
>sp|Q5L0S8|KGUA_GEOKA Guanylate kinase OS=Geobacillus kaustophilus
(strain HTA426) OX=235909 GN=gmk PE=3 SV=1
Length=205
Score = 80.5 bits (197), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 45/136 (33%), Positives = 66/136 (49%), Gaps = 0/136 (0%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I++ GP G+ +R+ L ++ +V TTR R+ EV G DY F +R+ FE I
Sbjct 9 IVMSGPSGVGKGTVRKALFSQPDINLHYSVSVTTRKPREGEVEGVDYFFRTREQFEQMIR 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
K +E E+ N YGT ID V + + GK L + Q +R + + IF+APPS
Sbjct 69 ENKLLEWAEYVGNYYGTPIDYVEKTLAEGKDVFLEIEVQGAMKVRRAFPEALFIFLAPPS 128
Query 602 QERLRALLAKEGKNPK 617
L + G K
Sbjct 129 LTELEKRIMGRGTESK 144
>sp|Q7NRL1|KGUA_CHRVO Guanylate kinase OS=Chromobacterium violaceum
(strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614
/ NCIMB 9131 / NCTC 9757) OX=243365 GN=gmk PE=3 SV=1
Length=210
Score = 80.9 bits (198), Expect = 5e-16, Method: Composition-based stats.
Identities = 58/189 (31%), Positives = 93/189 (49%), Gaps = 9/189 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I++ P G+ L L+ E ++ ++TR R E+ G+ YHF+ R AFE
Sbjct 10 IVVAPSGAGKTSLVAALLQAEPS-VELSISYSTRQARKGEIDGQHYHFIDRAAFEEMKDR 68
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
G F+E E N YGTS +R + +G+ LL + Q + +R IFIAPPS
Sbjct 69 GDFLEWAEVYGNCYGTSAPWIRGRLEAGRDILLEIDWQGAEQVRKVFPDAIGIFIAPPSI 128
Query 603 ERLRALLAKEGKNPKPEE--LREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI- 659
E L L G++ EE LR + E+++ +D +VN D ++A +L+ ++
Sbjct 129 EELERRL--RGRDTDTEEVILRRLASARAEIDKIA--EYDYIVVNDDFERARLDLISIVR 184
Query 660 -NKLDTEPQ 667
+L + PQ
Sbjct 185 AQRLRSAPQ 193
>sp|Q3YW11|KGUA_SHISS Guanylate kinase OS=Shigella sonnei (strain
Ss046) OX=300269 GN=gmk PE=3 SV=1
Length=207
Score = 80.5 bits (197), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 59/181 (33%), Positives = 86/181 (48%), Gaps = 9/181 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ + D S V HTTR R EV G Y FV+ F+ I
Sbjct 8 IVSAPSGAGKSSLIQALLKTQPLYDTQVS-VSHTTRQPRPGEVHGEHYFFVNHDEFKEMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
+ F+EH E N YGTS +++ QV+ +G L + Q + +R IFI PP
Sbjct 67 SRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLRL 658
S+ L L G++ + + + + EM HY +D IVN D D A +L +
Sbjct 127 SKIELDRRLRGRGQDSEEVIAKRMAQAVAEM----SHYAEYDYLIVNDDFDTALTDLKTI 182
Query 659 I 659
I
Sbjct 183 I 183
>sp|P60548|KGUA_SHIFL Guanylate kinase OS=Shigella flexneri OX=623
GN=gmk PE=3 SV=1
Length=207
Score = 80.5 bits (197), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 59/181 (33%), Positives = 86/181 (48%), Gaps = 9/181 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ + D S V HTTR R EV G Y FV+ F+ I
Sbjct 8 IVSAPSGAGKSSLIQALLKTQPLYDTQVS-VSHTTRQPRPGEVHGEHYFFVNHDEFKEMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
+ F+EH E N YGTS +++ QV+ +G L + Q + +R IFI PP
Sbjct 67 SRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLRL 658
S+ L L G++ + + + + EM HY +D IVN D D A +L +
Sbjct 127 SKIELDRRLRGRGQDSEEVIAKRMAQAVAEM----SHYAEYDYLIVNDDFDTALTDLKTI 182
Query 659 I 659
I
Sbjct 183 I 183
>sp|Q1R4U3|KGUA_ECOUT Guanylate kinase OS=Escherichia coli (strain
UTI89 / UPEC) OX=364106 GN=gmk PE=3 SV=2
Length=207
Score = 80.5 bits (197), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 59/181 (33%), Positives = 86/181 (48%), Gaps = 9/181 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ + D S V HTTR R EV G Y FV+ F+ I
Sbjct 8 IVSAPSGAGKSSLIQALLKTQPLYDTQVS-VSHTTRQPRPGEVHGEHYFFVNHDEFKEMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
+ F+EH E N YGTS +++ QV+ +G L + Q + +R IFI PP
Sbjct 67 SRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLRL 658
S+ L L G++ + + + + EM HY +D IVN D D A +L +
Sbjct 127 SKIELDRRLRGRGQDSEEVIAKRMAQAVAEM----SHYAEYDYLIVNDDFDTALTDLKTI 182
Query 659 I 659
I
Sbjct 183 I 183
>sp|P60546|KGUA_ECOLI Guanylate kinase OS=Escherichia coli (strain
K12) OX=83333 GN=gmk PE=1 SV=1
Length=207
Score = 80.5 bits (197), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 59/181 (33%), Positives = 86/181 (48%), Gaps = 9/181 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ + D S V HTTR R EV G Y FV+ F+ I
Sbjct 8 IVSAPSGAGKSSLIQALLKTQPLYDTQVS-VSHTTRQPRPGEVHGEHYFFVNHDEFKEMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
+ F+EH E N YGTS +++ QV+ +G L + Q + +R IFI PP
Sbjct 67 SRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLRL 658
S+ L L G++ + + + + EM HY +D IVN D D A +L +
Sbjct 127 SKIELDRRLRGRGQDSEEVIAKRMAQAVAEM----SHYAEYDYLIVNDDFDTALTDLKTI 182
Query 659 I 659
I
Sbjct 183 I 183
>sp|P60547|KGUA_ECOL6 Guanylate kinase OS=Escherichia coli O6:H1
(strain CFT073 / ATCC 700928 / UPEC) OX=199310 GN=gmk PE=3
SV=1
Length=207
Score = 80.5 bits (197), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 59/181 (33%), Positives = 86/181 (48%), Gaps = 9/181 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ + D S V HTTR R EV G Y FV+ F+ I
Sbjct 8 IVSAPSGAGKSSLIQALLKTQPLYDTQVS-VSHTTRQPRPGEVHGEHYFFVNHDEFKEMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
+ F+EH E N YGTS +++ QV+ +G L + Q + +R IFI PP
Sbjct 67 SRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLRL 658
S+ L L G++ + + + + EM HY +D IVN D D A +L +
Sbjct 127 SKIELDRRLRGRGQDSEEVIAKRMAQAVAEM----SHYAEYDYLIVNDDFDTALTDLKTI 182
Query 659 I 659
I
Sbjct 183 I 183
>sp|Q0TBG1|KGUA_ECOL5 Guanylate kinase OS=Escherichia coli O6:K15:H31
(strain 536 / UPEC) OX=362663 GN=gmk PE=3 SV=1
Length=207
Score = 80.5 bits (197), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 59/181 (33%), Positives = 86/181 (48%), Gaps = 9/181 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ + D S V HTTR R EV G Y FV+ F+ I
Sbjct 8 IVSAPSGAGKSSLIQALLKTQPLYDTQVS-VSHTTRQPRPGEVHGEHYFFVNHDEFKEMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
+ F+EH E N YGTS +++ QV+ +G L + Q + +R IFI PP
Sbjct 67 SRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLRL 658
S+ L L G++ + + + + EM HY +D IVN D D A +L +
Sbjct 127 SKIELDRRLRGRGQDSEEVIAKRMAQAVAEM----SHYAEYDYLIVNDDFDTALTDLKTI 182
Query 659 I 659
I
Sbjct 183 I 183
>sp|Q9PQS9|KGUA_UREPA Guanylate kinase OS=Ureaplasma parvum serovar
3 (strain ATCC 700970) OX=273119 GN=gmk PE=3 SV=1
Length=191
Score = 80.1 bits (196), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 56/186 (30%), Positives = 94/186 (51%), Gaps = 8/186 (4%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R + I+ GP G++ + +++N++ A ++ TTR +R+ EV G DY+FV+ + F+
Sbjct 3 RGKLIVFSGPSGVGKHTILSKIINRKDLNLAYSISMTTRKKREGEVNGVDYYFVNDEEFK 62
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR-TQSLKTL---RNSDLKPY 593
I + IE EF N YGT V ++ + GK +L + +LK L +N DL
Sbjct 63 KAILNNELIEWAEFVGNKYGTPRTIVEKLRDEGKNVILEIEVVGALKVLDLYKNDDLIS- 121
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+ PPS + L+ L K + I + T E+ + Y+ I+N + D A
Sbjct 122 -IFLLPPSIDELKKRLLKRNTETLETIKKRIQKATHEITIKD--YYQYNIINDNPDHAAN 178
Query 654 ELLRLI 659
+L +I
Sbjct 179 QLAEII 184
>sp|P75526|KGUA_MYCPN Guanylate kinase OS=Mycoplasma pneumoniae
(strain ATCC 29342 / M129 / Subtype 1) OX=272634 GN=gmk PE=3
SV=1
Length=239
Score = 81.3 bits (199), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 54/177 (31%), Positives = 84/177 (47%), Gaps = 3/177 (2%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
R ++ GP G++ L + L++ KD+ ++ TTR R+ E G DY F + FE
Sbjct 56 RIFVITGPSGVGKSSLVRCLIDHFKDKLRYSISATTRKMRNSETEGVDYFFKDKAEFEKL 115
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQ-SLKTLRNSDLKPYIIFIA 598
IAA F+E + N YGT Q+I++G +L + Q +L+ + +IFI
Sbjct 116 IAADAFVEWAMYNDNYYGTLKSQAEQIIHNGGNLVLEIEYQGALQVKQKYPNDVVLIFIK 175
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
PPS E L L K + + +E +Q GH F + N++ DK EL
Sbjct 176 PPSMEELLVRLKKRNDEDAITIQNRLKQAEKECQQ-IGH-FKYVVTNNEFDKTLAEL 230
>sp|Q827Q3|KGUA_STRAW Guanylate kinase OS=Streptomyces avermitilis
(strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893
/ NCIMB 12804 / NRRL 8165 / MA-4680) OX=227882 GN=gmk PE=3 SV=1
Length=197
Score = 80.1 bits (196), Expect = 6e-16, Method: Composition-based stats.
Identities = 59/186 (32%), Positives = 90/186 (48%), Gaps = 3/186 (2%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
P R R +L GP G++ + M KE +V TTR R E G Y FVS
Sbjct 13 PDARPRLTVLSGPSGVGKSTVVAH-MRKEHPEVWLSVSATTRKPRPGEKHGVHYFFVSDD 71
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
+ IA G+ +E EF N YGT +V + + G+ LL + Q + +R S + +
Sbjct 72 EMDKLIANGELLEWAEFAGNRYGTPRQAVLERLERGEPVLLEIDLQGARQVRESMPEALL 131
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
+F+APPS E L L G P PE + ++ + +E FD +VN+ ++ +E
Sbjct 132 VFLAPPSWEELVRRLTGRGTEP-PEVIERRLDAAK-VELAAEPEFDVTLVNTSVEDVARE 189
Query 655 LLRLIN 660
LL L++
Sbjct 190 LLALVD 195
>sp|Q0HE40|KGUA_SHESM Guanylate kinase OS=Shewanella sp. (strain
MR-4) OX=60480 GN=gmk PE=3 SV=1
Length=207
Score = 80.5 bits (197), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 53/184 (29%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R I+ P G++ L L+ + +V HTTR+ R EV G+ YHFV+ + F+
Sbjct 4 RGNLFIVSAPSGAGKSSLISALLKDKPADMQVSVSHTTRAPRPGEVNGQHYHFVNVEEFK 63
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
A I F E E N YGTS + + G L + Q + ++ + +FI
Sbjct 64 ALIEQNAFFEWAEVFGNYYGTSRHVIEHTLTQGIDVFLDIDWQGAQQVKAVMPEAIGVFI 123
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQEL 655
PPS++ L L G++ + + + EM HY +D IVN D D A ++
Sbjct 124 LPPSRDELERRLTGRGQDSQEVIASRMAQAVSEMS----HYKEYDFIIVNDDFDTALADM 179
Query 656 LRLI 659
+I
Sbjct 180 RAII 183
>sp|Q2NIH1|KGUA_AYWBP Guanylate kinase OS=Aster yellows witches'-broom
phytoplasma (strain AYWB) OX=322098 GN=gmk PE=3 SV=1
Length=211
Score = 80.5 bits (197), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 50/179 (28%), Positives = 82/179 (46%), Gaps = 3/179 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
IIL GP G+ +R+ L F +V TTR R E G+DYHF++++ FE I
Sbjct 10 IILSGPSGVGKATVRKALFEMTNHNFVYSVSATTRKPRPGEQDGKDYHFLTKEEFEKGIE 69
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL-KPYIIFIAPP 600
F+E +F + YGT ++ + GK L + + LR + IF+ PP
Sbjct 70 NNCFLEWAKFIDHYYGTPKKQIQDFLKQGKEVFLEIEVEGATHLRKKRMPNTVFIFLVPP 129
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
++ L L K G + ++ I + E H +D +VN ++ A ++ +I
Sbjct 130 KKKDLYDRLKKRGTEQEINIVQRIAKANNEFRL--AHKYDYIVVNDEVANAADRIIAII 186
>sp|Q2JQB9|KGUA_SYNJA Guanylate kinase OS=Synechococcus sp. (strain
JA-3-3Ab) OX=321327 GN=gmk PE=3 SV=1
Length=217
Score = 80.5 bits (197), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 56/185 (30%), Positives = 95/185 (51%), Gaps = 3/185 (2%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
PA R R ++L GP G+ L +L + + + S V TTR R E G +Y+F +R+
Sbjct 26 PATRGRLVVLTGPSGVGKGTLVSQLRQRHPELYFS-VSVTTRPPRPGEQEGVNYYFRTRE 84
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
F I A + +E ++ N YGT + V Q ++ G+ LL + + +R
Sbjct 85 EFLNLIEADELLEWAQYAGNFYGTPREIVFQKLSQGQDVLLEIELAGARQVRQQCPDAIR 144
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IF++PPS E L + + G++ + R + + +E++ + FD IVN +L++A QE
Sbjct 145 IFLSPPSLEELERRIRERGQDSEASIQRRLQQARKELDAKD--EFDYVIVNDNLEQALQE 202
Query 655 LLRLI 659
L L+
Sbjct 203 LEALL 207
>sp|P60554|KGUA_ONYPE Guanylate kinase OS=Onion yellows phytoplasma
(strain OY-M) OX=262768 GN=gmk PE=3 SV=1
Length=212
Score = 80.5 bits (197), Expect = 7e-16, Method: Compositional matrix adjust.
Identities = 49/179 (27%), Positives = 81/179 (45%), Gaps = 3/179 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +R+ L F +V TTR R E G+DYHF++++ FE I
Sbjct 10 IVLSGPSGVGKATVRKALFEMTNHNFVYSVSATTRKPRPGEQDGKDYHFLTKEEFEKGIE 69
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL-KPYIIFIAPP 600
F+E +F + YGT ++ + GK L + + LR + IF+ PP
Sbjct 70 NNCFLEWAKFIDHYYGTPKKQIQDFLKQGKEVFLEIEVEGATHLRKKRIPNTVFIFLVPP 129
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
++ L L K G + + I + E H +D +VN ++ A ++ +I
Sbjct 130 EKKALYDRLKKRGTEQEANIAKRIAKANNEFHL--AHKYDYIVVNDEVANAADRIIAII 186
>sp|Q3A523|KGUA_SYNC1 Guanylate kinase OS=Syntrophotalea carbinolica
(strain DSM 2380 / NBRC 103641 / GraBd1) OX=338963 GN=gmk
PE=3 SV=1
Length=210
Score = 80.1 bits (196), Expect = 8e-16, Method: Composition-based stats.
Identities = 54/179 (30%), Positives = 89/179 (50%), Gaps = 7/179 (4%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
++ P G+ L +++++ D ++ TTR RR+ E G DYHFV+ + F+ +A
Sbjct 9 VISAPSGAGKTSLCRQIVDIFPD-MRHSISFTTRPRRNGETDGVDYHFVTPEVFDTMVAE 67
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
G F E N YGT++ ++++ G+ LL + Q L+ + IFI PPS
Sbjct 68 GAFAEWARVHGNCYGTALATLQEAREQGQDLLLDIDCQGAAQLKRNCPDDVFIFILPPSF 127
Query 603 ERLRALLAKEGKNPKPEEL--REIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
E L L G+N E+ R + RE+ + ++D IVN DL +A +E +I
Sbjct 128 EELERRL--RGRNTDTAEVIARRLDNARREIRELV--WYDYLIVNEDLPRAVEEFKSII 182
>sp|Q9Z961|KGUA_CHLPN Guanylate kinase OS=Chlamydia pneumoniae
OX=83558 GN=gmk PE=3 SV=1
Length=205
Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 55/170 (32%), Positives = 84/170 (49%), Gaps = 3/170 (2%)
Query 486 GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKF 545
P G+ L + L + FA + TTR R+ EV G+DYHFVS + F+ +
Sbjct 26 APAGVGKTTLVRMLEQEFSSAFAETISVTTRKPREGEVPGKDYHFVSHEEFQRLLDRQAL 85
Query 546 IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERL 605
+E YGTS+ + ++ + GK + + Q +R S + IFIAPPSQE L
Sbjct 86 LEWVFLFGECYGTSMLEIERIWSLGKHAVAVIDIQGALFIR-SRMPSVSIFIAPPSQEEL 144
Query 606 RALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
LA G + +E +E + +E + FD I+N DL++AY+ L
Sbjct 145 ERRLASRGSEEGSQR-KERLEHSL-IELAAANQFDYVIINDDLNQAYRVL 192
>sp|Q9KXS0|KGUA_STRCO Guanylate kinase OS=Streptomyces coelicolor
(strain ATCC BAA-471 / A3(2) / M145) OX=100226 GN=gmk PE=3
SV=1
Length=197
Score = 79.3 bits (194), Expect = 1e-15, Method: Composition-based stats.
Identities = 59/186 (32%), Positives = 91/186 (49%), Gaps = 3/186 (2%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
P R R +L GP G++ + M KE +V TTR R E G Y FVS +
Sbjct 13 PDARPRLTVLSGPSGVGKSTVVAH-MRKEHPEVWLSVSATTRRPRPGEQHGVHYFFVSDE 71
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
+ IA G+ +E EF N YGT +V + + +G+ LL + Q + +R S + +
Sbjct 72 EMDKLIANGELLEWAEFAGNRYGTPRTAVLERLEAGEPVLLEIDLQGARQVRESMPEARL 131
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
+F+APPS + L L G+ +P E+ E ++E FD +VN+ ++ +E
Sbjct 132 VFLAPPSWDELVRRLT--GRGTEPPEVIERRLAAAKVELAAEPEFDQTLVNTSVEDVARE 189
Query 655 LLRLIN 660
LL L N
Sbjct 190 LLALTN 195
>sp|Q3J2A5|KGUA_CERS4 Guanylate kinase OS=Cereibacter sphaeroides
(strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG
2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) OX=272943 GN=gmk
PE=3 SV=1
Length=211
Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 61/185 (33%), Positives = 91/185 (49%), Gaps = 11/185 (6%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
A R +IL P G++ L +RL + RF+ V TTR+ R EV GRDY+F +R
Sbjct 2 ARRGLLLILSSPSGAGKSTLSKRLTAWDPSIRFS--VSATTRAPRPGEVDGRDYYFRTRD 59
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
F A + AG+ +EH E N YG+ V + + G L + Q + +RNS L +
Sbjct 60 EFIAAVEAGEMLEHAEVFGNFYGSPKAPVEKALEQGHDTLFDIDWQGGQQIRNSSLGRDV 119
Query 595 --IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDK 650
IF+ PPS L L ++ EE+ I + + H+ +D +VN DLD
Sbjct 120 VSIFVLPPSIGELDRRLRSRAQD--SEEV--IATRMARSKDEISHWAEYDYVLVNRDLDL 175
Query 651 AYQEL 655
A ++L
Sbjct 176 AEEQL 180
>sp|Q8XD88|KGUA_ECO57 Guanylate kinase OS=Escherichia coli O157:H7
OX=83334 GN=gmk PE=3 SV=1
Length=207
Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 60/181 (33%), Positives = 87/181 (48%), Gaps = 9/181 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ + D S V HTTR R EV G Y FV+ F+ I
Sbjct 8 IVSAPSGAGKSSLIQALLKTQPLYDTQVS-VSHTTRQPRPGEVHGEHYFFVNHDEFKEMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
+ F+EH E N YGTS +++ QV+ +G L + Q + +R IFI PP
Sbjct 67 SRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLRL 658
S+ L L G++ EE+ I ++ + HY +D IVN D D A +L +
Sbjct 127 SKIELDRRL--RGRDQDSEEV--IAKRMAQAVAEMSHYAEYDYLIVNDDFDTALTDLKTI 182
Query 659 I 659
I
Sbjct 183 I 183
>sp|P60555|KGUA_PROMM Guanylate kinase OS=Prochlorococcus marinus
(strain MIT 9313) OX=74547 GN=gmk PE=3 SV=1
Length=189
Score = 79.0 bits (193), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 53/178 (30%), Positives = 88/178 (49%), Gaps = 3/178 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
++ GP G+ L ++L+ + + S + TTR R E+ G Y F++R F + A
Sbjct 12 VITGPSGVGKGSLVKQLLELHPEIWLS-ISATTREARQGEIEGDHYFFLNRDRFAELVQA 70
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
G +E EF N YGT V Q ++ G+ LL + + + +R S + + IF+APPS
Sbjct 71 GGCLEWAEFAGNRYGTPRQPVEQQLSLGRPVLLEIELEGARQVRRSFPEAFQIFLAPPSF 130
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
E L + +P+ E ++ + + RE E FD ++N +L A EL L+
Sbjct 131 EELERRIRGRATDPE-EAIQRRLARARE-ELMAQQEFDAVVINDNLQVAVIELESLMG 186
>sp|P60552|KGUA_LACJO Guanylate kinase OS=Lactobacillus johnsonii
(strain CNCM I-12250 / La1 / NCC 533) OX=257314 GN=gmk PE=3
SV=1
Length=204
Score = 79.3 bits (194), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 40/134 (30%), Positives = 68/134 (51%), Gaps = 0/134 (0%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++L GP G+ ++ ++ ++ F +V TTR R EV G+DY+FVS F+ I
Sbjct 8 LVLSGPSGVGKGTVKSAMVKQKAFSFEYSVSMTTRKPRPGEVNGKDYYFVSEDRFQEAIK 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+ +E+ E+ N YGT + V++++N GK LL + K +R IF+ PP
Sbjct 68 GNELLEYNEYVGNHYGTPLAPVQKMLNEGKDVLLEIDVNGAKQVRKLMPDGVFIFLTPPD 127
Query 602 QERLRALLAKEGKN 615
L+ + G +
Sbjct 128 LHELKHRIVNRGTD 141
>sp|Q12DV7|KGUA_POLSJ Guanylate kinase OS=Polaromonas sp. (strain
JS666 / ATCC BAA-500) OX=296591 GN=gmk PE=3 SV=1
Length=206
Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 54/180 (30%), Positives = 88/180 (49%), Gaps = 5/180 (3%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++ P G++ L + LM + AV HTTR R QE GR+Y F+S + F++ +
Sbjct 8 FVVAAPSGAGKSSLVKALMELDSA-IQPAVSHTTRPPRGQEKHGREYFFLSPEEFDSMVQ 66
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
F+E + YGTS ++ + I GK +L + Q ++ +IFI PPS
Sbjct 67 RDAFLEWAHVHGHRYGTSRQAIEERIAHGKDVILEIDFQGAINIKRIFSNAVLIFILPPS 126
Query 602 QERLRALLAKEGKN-PKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
E LR+ L + G++ P+ ELR K E FD I+N ++A +L +++
Sbjct 127 WEELRSRLQRRGEDSPEVIELR---LKNAATEMAQAREFDFVIINELFERAVFDLKTIVH 183
>sp|Q8GAU4|KGUA_STRKA Guanylate kinase OS=Streptomyces kasugaensis
OX=1946 GN=gmk PE=3 SV=1
Length=205
Score = 79.0 bits (193), Expect = 2e-15, Method: Composition-based stats.
Identities = 59/188 (31%), Positives = 90/188 (48%), Gaps = 9/188 (5%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
P R R +L GP G++ + L + + S V TTR R E G Y FV +
Sbjct 13 PDARPRLTVLSGPSGVGKSTVVAHLRTVHPEVWLS-VSATTRKPRPGEQHGVQYFFVDDE 71
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
F+ +A G+ +E EF N YGT +V + +G+ LL + Q + +R S ++
Sbjct 72 EFDKLVANGELLEWAEFAGNRYGTPRKAVLDRLEAGEPVLLEIDLQGARQVRESMADAHL 131
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEK---TREMEQNNGHYFDTAIVNSDLDKA 651
+F+APPS E L L G E EIIE+ ++E FD +VN+ ++
Sbjct 132 VFLAPPSWEELVRRLTGRGT-----EAPEIIERRLAAAKVELAAETEFDVTLVNTSVEDV 186
Query 652 YQELLRLI 659
+ELL L+
Sbjct 187 SRELLALM 194
>sp|Q0S0L7|KGUA_RHOJR Guanylate kinase OS=Rhodococcus jostii (strain
RHA1) OX=101510 GN=gmk PE=3 SV=1
Length=207
Score = 79.0 bits (193), Expect = 2e-15, Method: Composition-based stats.
Identities = 58/187 (31%), Positives = 91/187 (49%), Gaps = 11/187 (6%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R R ++L GP G++ + RL+ + +V TTR R EV G+DY F SR F+
Sbjct 16 RGRLVVLAGPSAVGKSSV-VRLLRERMPELVFSVSATTRDPRPGEVDGKDYRFTSRDEFQ 74
Query 538 ADIAAGKFIEHGEFEK--NLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
I +G+ +E E L GT VR+ I GK L+ + + +R + + ++
Sbjct 75 RMIESGELLEWAEIHGGLQLSGTPAAPVRRAIEQGKPVLVEVDLAGARAVRAAMPEALLV 134
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEK---TREMEQNNGHYFDTAIVNSDLDKAY 652
F+APPS + L L G E E++E+ T +E FD IVN D+ ++
Sbjct 135 FMAPPSWDVLVERLTGRGT-----ESAEVVERRLATARVELEAQDEFDEVIVNEDVSRSC 189
Query 653 QELLRLI 659
EL+ L+
Sbjct 190 DELVSLL 196
>sp|Q1IW06|KGUA_DEIGD Guanylate kinase OS=Deinococcus geothermalis
(strain DSM 11300 / AG-3a) OX=319795 GN=gmk PE=3 SV=1
Length=242
Score = 79.7 bits (195), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 53/175 (30%), Positives = 85/175 (49%), Gaps = 5/175 (3%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I++ G G+ LR+R + + D F S TTR R E G DY FV+ + F +
Sbjct 25 IVMTGASGVGKGTLRERWLAGQ-DVFYS-TSWTTREARPGERDGVDYVFVTPEVFLEKVR 82
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQ-SLKTLRNSDLKPYIIFIAPP 600
F+EH +F N YGT + + + G+ +L + + +++ + ++FI PP
Sbjct 83 QNGFLEHAQFVGNHYGTPTEPIEAALARGQDVVLEIEVEGAMQVKERMGEEAVLVFIMPP 142
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
S LR L PE + + +++ R+ E H F IVN DLD+A +EL
Sbjct 143 SLTELRRRLTGRATE-TPERIEKRLQRARD-EIMAAHAFRYVIVNDDLDRAVREL 195
>sp|Q6F7H0|KGUA_ACIAD Guanylate kinase OS=Acinetobacter baylyi
(strain ATCC 33305 / BD413 / ADP1) OX=62977 GN=gmk PE=3 SV=1
Length=207
Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 54/179 (30%), Positives = 85/179 (47%), Gaps = 3/179 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++ G+ L + L+ + + S V HTTR +R E+ G YHF +++ F + +
Sbjct 6 FVVSAASGTGKTSLVKALLERVTNLHVS-VSHTTRGQRPGELDGVHYHFTTKENFLSQVE 64
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
FIE+ E N YGTS +V+Q + G LL + Q + +R + IFI PPS
Sbjct 65 DNGFIEYAEVFGNYYGTSQATVKQQLAKGHDVLLEIDWQGAQQVRRIFPESKQIFILPPS 124
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
Q LR L+ G + + +M+Q FD I+N D +KA +L +I
Sbjct 125 QFDLRQRLSNRGTDAVDVIEHRLSCAVEDMQQYVN--FDYIIINDDFNKALHDLESVIT 181
>sp|Q895Q5|KGUA_CLOTE Guanylate kinase OS=Clostridium tetani (strain
Massachusetts / E88) OX=212717 GN=gmk PE=3 SV=1
Length=208
Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 48/179 (27%), Positives = 90/179 (50%), Gaps = 4/179 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I++ GP G+ + + L+ + F +V TTR R+ E+ G+ Y+F+S++ FE I
Sbjct 7 IVISGPSGTGKGTVCKELLRN--NNFWFSVSSTTRDPREGEIQGKSYYFMSKEEFEDKIK 64
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
F+E+ + N YGT V ++++ GK +L + Q ++ + + IFI PPS
Sbjct 65 ENDFLEYAKVYGNYYGTPKSKVIEMLDKGKDVILEIDIQGALQVKENYKEGIFIFILPPS 124
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
E L+ + K G + + K+ E N ++ A+VN + A +++ +I+
Sbjct 125 MEELKNRIIKRGTETEESLMTRF--KSAYKEINYVSKYNYAVVNDKVHDAVEKIQSIIS 181
>sp|Q89AC8|KGUA_BUCBP Guanylate kinase OS=Buchnera aphidicola
subsp. Baizongia pistaciae (strain Bp) OX=224915 GN=gmk PE=3
SV=1
Length=207
Score = 78.6 bits (192), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 53/181 (29%), Positives = 88/181 (49%), Gaps = 7/181 (4%)
Query 482 IILIGPQNCGQNELRQRLMNKEK-DRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+N +V HTTR R E G+ Y+F+S F+ I
Sbjct 7 FIVSAPSGTGKSSLIQALVNTHPLYSIKVSVSHTTRIIRPGECHGKHYYFISNTEFQNMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
+F+E+ + N YGTS + +++G L + Q + +RN + IFI PP
Sbjct 67 DKEEFLEYAKVFNNYYGTSKKQINYGLSTGTDVFLDIDWQGARQIRNKLPESKSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLRL 658
S+E L L K G++ + + + EM+ HY +D I+N + + A +L ++
Sbjct 127 SKEELYRRLCKRGQDSDIIIKKRMNQAVSEMK----HYIDYDYLIINDNFNLAVSDLYKI 182
Query 659 I 659
I
Sbjct 183 I 183
>sp|Q5HTT7|KGUA_CAMJR Guanylate kinase OS=Campylobacter jejuni
(strain RM1221) OX=195099 GN=gmk PE=3 SV=1
Length=205
Score = 78.6 bits (192), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 47/189 (25%), Positives = 97/189 (51%), Gaps = 5/189 (3%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ GP G++ L ++L ++ +D ++ TTR R+ E G YHF+S + F+ I
Sbjct 6 LLISGPSGAGKSTLLKKLFDEFEDELYFSISSTTRKPREGEKNGIHYHFISHEEFQKGID 65
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-IFIAPP 600
+ F+E +N YGTS+ + +++GKI + + Q K R + +FI
Sbjct 66 SDHFLEWARVHENFYGTSLKHTQNALDNGKIVVFDIDVQGFKIARKKMADKIVSVFITTK 125
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL--LRL 658
+++ L+ L K + + + + + EM++ + +D I+N +L ++Y+ L + +
Sbjct 126 NKDELKKRLIKRNTDTIIQLEKRLQNASDEMKELSE--YDYLIINDELKQSYEALRAILI 183
Query 659 INKLDTEPQ 667
+K T+ Q
Sbjct 184 AHKFRTKGQ 192
>sp|Q9K9Y2|KGUA_HALH5 Guanylate kinase OS=Halalkalibacterium halodurans
(strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM
9153 / C-125) OX=272558 GN=gmk PE=3 SV=1
Length=204
Score = 78.2 bits (191), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 49/140 (35%), Positives = 71/140 (51%), Gaps = 3/140 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ + L K +V TTR+ R EV G +Y F SR+ FEA I
Sbjct 9 IVLSGPAGVGKGTVCSAL-RKHDTNIQYSVSATTRAPRKGEVDGVNYFFKSREQFEAMIE 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+ +E E+ N YGT I VR+ I+SGK +L + Q +R + IF+ PPS
Sbjct 68 KEELLEWAEYVGNYYGTPIQYVRETIDSGKDIILEIEVQGALKVRERFPEGVFIFLMPPS 127
Query 602 QERLRALLAKEGKNPKPEEL 621
LR+ + G+ + EE+
Sbjct 128 LAELRSRIV--GRGTETEEV 145
>sp|Q1CUI1|KGUA_HELPH Guanylate kinase OS=Helicobacter pylori
(strain HPAG1) OX=357544 GN=gmk PE=3 SV=1
Length=206
Score = 78.2 bits (191), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 56/182 (31%), Positives = 90/182 (49%), Gaps = 5/182 (3%)
Query 482 IILIGPQNCGQNELRQRLMNK-EKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
+IL GP G++ L + L K K F+ + TTR R+ EV G Y+FVS + F+ I
Sbjct 8 LILSGPSGAGKSTLTKYLQEKIPKTHFSLST--TTRKPREGEVDGLHYNFVSEEEFKQGI 65
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
G+F+E + YGTS V + + GKI + + Q + L+ +FI+
Sbjct 66 EKGQFLEWAIVHNHYYGTSKIPVEKALKEGKIVIFDIDVQGHEILKKHYPNACSVFISTK 125
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
+QE L+ L G + K + +I +EM+ FD I+N DL+K+ + +L +
Sbjct 126 NQEILKERLLLRGTDSKETIEKRLINAYKEMQCLES--FDYLIINEDLEKSKEIILSIAK 183
Query 661 KL 662
L
Sbjct 184 TL 185
>sp|Q9PNB8|KGUA_CAMJE Guanylate kinase OS=Campylobacter jejuni
subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
OX=192222 GN=gmk PE=3 SV=1
Length=207
Score = 78.6 bits (192), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 47/189 (25%), Positives = 97/189 (51%), Gaps = 5/189 (3%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ GP G++ L ++L ++ +D ++ TTR R+ E G YHF+S + F+ I
Sbjct 8 LLISGPSGAGKSTLLKKLFDEFEDELYFSISSTTRKPREGEKNGIHYHFISHEEFQKGID 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-IFIAPP 600
+ F+E +N YGTS+ + +++GKI + + Q K R + +FI
Sbjct 68 SDHFLEWARVHENFYGTSLKHTQNALDNGKIVVFDIDVQGFKIARKKMADKIVSVFITTK 127
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL--LRL 658
+++ L+ L K + + + + + EM++ + +D I+N +L ++Y+ L + +
Sbjct 128 NKDELKKRLIKRNTDTIIQLEKRLQNASDEMKELSE--YDYLIINDELKQSYEALRAILI 185
Query 659 INKLDTEPQ 667
+K T+ Q
Sbjct 186 AHKFRTKGQ 194
>sp|Q7MPW9|KGUA_VIBVY Guanylate kinase OS=Vibrio vulnificus (strain
YJ016) OX=196600 GN=gmk PE=3 SV=1
Length=207
Score = 78.2 bits (191), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 52/178 (29%), Positives = 79/178 (44%), Gaps = 3/178 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDR-FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+ P G++ L ++ K +V HTTR R E G YHFV ++ FE I
Sbjct 8 IVSAPSGAGKSSLISAMLEKNPTYAMKVSVSHTTRGMRPGEQDGVHYHFVEKEHFEDLIT 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+F+E+ E N YGTS + ++ G L + Q + +R IFI PPS
Sbjct 68 KGEFLEYAEVFGNYYGTSRVWIENTLDKGIDVFLDIDWQGARQIREQMPHAKSIFILPPS 127
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
L L G++ + + + E E+ N +D I+N D D A + +I
Sbjct 128 NGELERRLNTRGQDSEAVIAKRMAEAKSEISHYNE--YDYVIINDDFDTALMDFKAII 183
>sp|Q8DDV6|KGUA_VIBVU Guanylate kinase OS=Vibrio vulnificus (strain
CMCP6) OX=216895 GN=gmk PE=3 SV=1
Length=207
Score = 78.2 bits (191), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 52/178 (29%), Positives = 79/178 (44%), Gaps = 3/178 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDR-FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+ P G++ L ++ K +V HTTR R E G YHFV ++ FE I
Sbjct 8 IVSAPSGAGKSSLISAMLEKNPTYAMKVSVSHTTRGMRPGEQDGVHYHFVEKEHFEDLIT 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+F+E+ E N YGTS + ++ G L + Q + +R IFI PPS
Sbjct 68 KGEFLEYAEVFGNYYGTSRVWIENTLDKGIDVFLDIDWQGARQIREQMPHAKSIFILPPS 127
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
L L G++ + + + E E+ N +D I+N D D A + +I
Sbjct 128 NGELERRLNTRGQDSEAVIAKRMAEAKSEISHYNE--YDYVIINDDFDTALMDFKAII 183
>sp|P56103|KGUA_HELPY Guanylate kinase OS=Helicobacter pylori
(strain ATCC 700392 / 26695) OX=85962 GN=gmk PE=3 SV=1
Length=206
Score = 78.2 bits (191), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 56/182 (31%), Positives = 90/182 (49%), Gaps = 5/182 (3%)
Query 482 IILIGPQNCGQNELRQRLMNK-EKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
+IL GP G++ L + L K K F+ + TTR R+ EV G Y+FVS + F+ I
Sbjct 8 LILSGPSGAGKSTLTKYLQEKIPKTHFSLST--TTRKPREGEVDGLHYNFVSEEEFKQGI 65
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
G+F+E + YGTS V + + GKI + + Q + L+ +FI+
Sbjct 66 EKGQFLEWAIVHNHYYGTSKIPVEKALKEGKIVIFDIDVQGHEILKKHYPNACSVFISTK 125
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
+QE L+ L G + K + +I +EM+ FD I+N DL+K+ + +L +
Sbjct 126 NQEILKERLLLRGTDSKETIEKRLINAYKEMQCLES--FDYLIINEDLEKSKEIILSIAK 183
Query 661 KL 662
L
Sbjct 184 TL 185
>sp|Q9KNM4|KGUA_VIBCH Guanylate kinase OS=Vibrio cholerae serotype
O1 (strain ATCC 39315 / El Tor Inaba N16961) OX=243277
GN=gmk PE=1 SV=2
Length=207
Score = 78.2 bits (191), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 54/180 (30%), Positives = 82/180 (46%), Gaps = 7/180 (4%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDR-FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+ P G++ L L+ + +V HTTR R E G YHFV ++ F I
Sbjct 8 IVSAPSGAGKSSLIAALLEQNPTYAMKVSVSHTTRGMRPGEQDGVHYHFVEKEHFIELIG 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+F+E+ E N YGTS + +N G L + Q + +R+ + IFI PPS
Sbjct 68 KGEFLEYAEVFGNYYGTSRVWIENTLNKGIDVFLDIDWQGARQIRSQMPEAKSIFILPPS 127
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLRLI 659
+E L L G++ I ++ E + HY +D I+N D D A + +I
Sbjct 128 KEELERRLNTRGQDSDA----VIAKRMGEAKSEISHYSEYDYVIINDDFDVALMDFKAII 183
>sp|Q98PN5|KGUA_MYCPU Guanylate kinase OS=Mycoplasmopsis pulmonis
(strain UAB CTIP) OX=272635 GN=gmk PE=3 SV=1
Length=196
Score = 77.8 bits (190), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 51/190 (27%), Positives = 96/190 (51%), Gaps = 7/190 (4%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+++ ++L+GP G+ + + L + + + + TTR +R+ E+ G Y F+S++ F
Sbjct 5 HKRNIVLLVGPSGVGKGTIEKILFESKTLKLSLSRSATTRKKREGEINGIHYFFISKEEF 64
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLR-----NSDLK 591
E+ I +F+E E N YGT + + + + G+I +L + T K + D
Sbjct 65 ESKIENDEFMEWNEHFDNYYGTLLSEILLIFSQGRIPVLEVETYGAKKILQKYKDKKDFN 124
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
IF+ PPS E L + K G + K E++ + K +E E + F+ I N ++A
Sbjct 125 WITIFVDPPSFEELENRIIKRGTDTK-EKIAIRMAKAKE-ELKDRDLFEFKITNHTPEQA 182
Query 652 YQELLRLINK 661
+E+ ++I K
Sbjct 183 AEEIEKIILK 192
>sp|Q8Y672|KGUA_LISMO Guanylate kinase OS=Listeria monocytogenes
serovar 1/2a (strain ATCC BAA-679 / EGD-e) OX=169963 GN=gmk
PE=1 SV=1
Length=205
Score = 77.8 bits (190), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 40/132 (30%), Positives = 66/132 (50%), Gaps = 0/132 (0%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +R+ + + F ++ TTR R+ E G DY+F SR+ FE I
Sbjct 8 IVLSGPSGVGKGTVREAVFKDPETSFDYSISMTTRLPREGEQDGVDYYFRSREVFEQAIK 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
GK +E+ E+ N YGT ++ V + + +G L + Q +R + + IF+ PP
Sbjct 68 DGKMLEYAEYVGNYYGTPLEYVEEKLAAGVDIFLEIEVQGAMQVRKAMPEGIFIFLTPPD 127
Query 602 QERLRALLAKEG 613
L+ + G
Sbjct 128 LSELKNRIIGRG 139
>sp|Q71YI9|KGUA_LISMF Guanylate kinase OS=Listeria monocytogenes
serotype 4b (strain F2365) OX=265669 GN=gmk PE=3 SV=1
Length=205
Score = 77.8 bits (190), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 40/132 (30%), Positives = 66/132 (50%), Gaps = 0/132 (0%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ +R+ + + F ++ TTR R+ E G DY+F SR+ FE I
Sbjct 8 IVLSGPSGVGKGTVREAVFKDPETSFDYSISMTTRLPREGEQDGVDYYFRSREVFEQAIK 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
GK +E+ E+ N YGT ++ V + + +G L + Q +R + + IF+ PP
Sbjct 68 DGKMLEYAEYVGNYYGTPLEYVEEKLAAGVDIFLEIEVQGAMQVRKAMPEGIFIFLTPPD 127
Query 602 QERLRALLAKEG 613
L+ + G
Sbjct 128 LSELKNRIIGRG 139
>sp|Q602T6|KGUA_METCA Guanylate kinase OS=Methylococcus capsulatus
(strain ATCC 33009 / NCIMB 11132 / Bath) OX=243233 GN=gmk
PE=3 SV=1
Length=204
Score = 77.8 bits (190), Expect = 4e-15, Method: Composition-based stats.
Identities = 54/179 (30%), Positives = 85/179 (47%), Gaps = 7/179 (4%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
++ P G+ L L D A +V HTTR +R EV G+DY FV + FE IA
Sbjct 8 VISAPSGAGKTSLVSALCAGAPD-LAVSVSHTTRPQRPGEVPGQDYWFVDKAEFEKMIAN 66
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
F+E+ N YGT+ +V +V+ +G+ +L + Q + +R +FI PPS+
Sbjct 67 EAFLEYARVFDNYYGTAKTTVEEVLATGRDAVLEIDWQGARQVRRLMPACVSVFILPPSR 126
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLRLI 659
+ L L ++ + R + EM HY +D IVN D + A +L ++
Sbjct 127 QALEQRLRTRQQDSEAVIARRMEAAISEMS----HYAEYDYLIVNDDFNLALNQLRAIV 181
>sp|Q9ZMB7|KGUA_HELPJ Guanylate kinase OS=Helicobacter pylori
(strain J99 / ATCC 700824) OX=85963 GN=gmk PE=3 SV=1
Length=206
Score = 77.8 bits (190), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 56/182 (31%), Positives = 90/182 (49%), Gaps = 5/182 (3%)
Query 482 IILIGPQNCGQNELRQRLMNK-EKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
+IL GP G++ L + L K K F+ + TTR R+ EV G Y+FVS + F+ I
Sbjct 8 LILSGPSGAGKSTLTKYLQEKIPKTHFSLST--TTRKPREGEVDGLHYNFVSEEEFKQGI 65
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
G+F+E + YGTS V + + GKI + + Q + L+ +FI+
Sbjct 66 EKGQFLEWAIVHNHYYGTSKIPVEKALKEGKIVIFDIDVQGHEILKKHYPNACSVFISTK 125
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
+QE L+ L G + K + +I +EM+ FD I+N DL+K+ + +L +
Sbjct 126 NQEILKERLLLRGTDSKETIEKRLINAYKEMQCLES--FDYLIINEDLEKSKEIILSIAK 183
Query 661 KL 662
L
Sbjct 184 TL 185
>sp|Q92QZ2|KGUA_RHIME Guanylate kinase OS=Rhizobium meliloti (strain
1021) OX=266834 GN=gmk PE=3 SV=1
Length=219
Score = 78.2 bits (191), Expect = 5e-15, Method: Compositional matrix adjust.
Identities = 53/187 (28%), Positives = 91/187 (49%), Gaps = 8/187 (4%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A R +++ P G++ + + L+ + D + +V TTRSRR E+ GR Y F S +
Sbjct 12 ARRGLMLVISSPSGAGKSTIARNLLEADPD-LSISVSVTTRSRRPSEIEGRHYFFKSIRE 70
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI- 594
FEA A +E E N YGT D+V + + G+ L + Q + L+ +
Sbjct 71 FEALRATDSLLEWAEVHGNYYGTPRDAVEKAMGEGRDMLFDIDWQGAQQLQEKMAGDVVS 130
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAY 652
IFI PPS L++ L + ++ + + E+E H+ +D +VN DLD+A+
Sbjct 131 IFILPPSMAELQSRLHRRAEDSEEVIATRLANSRAEIE----HWREYDYIVVNDDLDRAF 186
Query 653 QELLRLI 659
+ ++
Sbjct 187 SSVRAIV 193
>sp|Q6G053|KGUA_BARQU Guanylate kinase OS=Bartonella quintana
(strain Toulouse) OX=283165 GN=gmk PE=3 SV=1
Length=221
Score = 77.8 bits (190), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 59/194 (30%), Positives = 97/194 (50%), Gaps = 13/194 (7%)
Query 464 LTYEEMSLYHQPANRKRPIILI--GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQ 521
+T+ E L + +++R + I P G++ L RL+ K+ + +V TTR RR
Sbjct 1 MTFFESELSAKKRDQRRGFLFILSSPSGAGKSTL-SRLLLKDA-QLERSVSVTTRQRRPS 58
Query 522 EVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS 581
EV G YHFVS+Q FE +FIE E N YGT SV +++G+ L + Q
Sbjct 59 EVDGFHYHFVSKQEFECKRDGDEFIEWAEVHGNYYGTLRKSVENALSAGRDILFDIDYQG 118
Query 582 LKTLRNSDLKPYI-IFIAPPSQERLRALLAKEGKNPKPEELREIIE---KTREMEQNNGH 637
+ L+ + IFI PPS + L L + + E+ ++II K + E +
Sbjct 119 TEQLQKKMPGDTVSIFILPPSMKELILRLHR-----RAEDSQDIINLRLKNAQTEMQHWR 173
Query 638 YFDTAIVNSDLDKA 651
++D ++N DL+++
Sbjct 174 FYDYVVINKDLNQS 187
>sp|Q5FJH2|KGUA_LACAC Guanylate kinase OS=Lactobacillus acidophilus
(strain ATCC 700396 / NCK56 / N2 / NCFM) OX=272621 GN=gmk
PE=3 SV=1
Length=204
Score = 77.4 bits (189), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 50/189 (26%), Positives = 91/189 (48%), Gaps = 10/189 (5%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A++ ++L GP G+ ++ ++ + F +V TTR R EV G+DY+FVS
Sbjct 2 ADKGLLLVLSGPSGVGKGTVKSAIVENKVFPFEYSVSMTTRKPRPGEVNGKDYYFVSEGR 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F+ I G+ +E+ + + YGT + V+++++ GK LL + + +R I
Sbjct 62 FKEAINNGELLEYNNYVGHYYGTPLGPVKEMLHEGKDVLLEIDVNGAQKVREKMPDGVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTR----EMEQNNGHYFDTAIVNSDLDKA 651
F+ PP L L G + + +R I++ R EME +D A+VN + A
Sbjct 122 FLTPPDLHTLHLRLEHRGTESE-DVIRGRIKQARNEILEMED-----YDYAVVNDTVANA 175
Query 652 YQELLRLIN 660
+ +++
Sbjct 176 VDHIKAIVD 184
>sp|Q3JBT3|KGUA_NITOC Guanylate kinase OS=Nitrosococcus oceani
(strain ATCC 19707 / BCRC 17464 / JCM 30415 / NCIMB 11848 /
C-107) OX=323261 GN=gmk PE=3 SV=1
Length=203
Score = 77.4 bits (189), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 52/180 (29%), Positives = 83/180 (46%), Gaps = 3/180 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+ P G+ L + L D ++ HTTR R E G DYHFV+ FE
Sbjct 6 FIVAAPSGAGKTSLVKALAASMAD-IRLSISHTTRPPRPGEQDGMDYHFVTEAIFETMEG 64
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G F+EH + + YGT+ +SV ++ G +L + Q + ++ IFI PPS
Sbjct 65 GGGFLEHAQVFGHRYGTAKESVLPLLAQGMDVILEIDWQGRRQVQAQFPHCVSIFILPPS 124
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINK 661
+E L L G++ + R + + E+ N FD +VN D + A+ +L ++
Sbjct 125 RETLEHRLRLRGQDTEAVVARRMGDACAEISHYN--EFDYLVVNDDFEVAHTDLRAIVQS 182
>sp|P57509|KGUA_BUCAI Guanylate kinase OS=Buchnera aphidicola
subsp. Acyrthosiphon pisum (strain APS) OX=107806 GN=gmk PE=3
SV=1
Length=207
Score = 77.4 bits (189), Expect = 7e-15, Method: Compositional matrix adjust.
Identities = 53/183 (29%), Positives = 92/183 (50%), Gaps = 9/183 (5%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFAS--AVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
I+ P G++ L Q L+ K K + + ++ HTTR R E+ G+ Y+F+S++ FE
Sbjct 7 FIISAPSGTGKSSLIQGLL-KSKTLYNTRVSISHTTRIIRPGELHGKHYYFISKKEFEIM 65
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
I F+E+ + N YGTS + +++ SG L + Q K ++ K IF+ P
Sbjct 66 IKQEYFLEYAKVFSNYYGTSRKYIEKMLFSGIDVFLDIDWQGAKQIKCKMPKSKSIFLLP 125
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLR 657
PS++ L L + G++ + + EM+ HY +D I+N D +A +L+
Sbjct 126 PSKDTLYKRLRERGQDSDSVIANRMEKAVDEMQ----HYSEYDYLIINDDFKQAVNDLIT 181
Query 658 LIN 660
+I
Sbjct 182 IIT 184
>sp|Q2J840|KGUA_FRACC Guanylate kinase OS=Frankia casuarinae (strain
DSM 45818 / CECT 9043 / HFP020203 / CcI3) OX=106370 GN=gmk
PE=3 SV=1
Length=184
Score = 76.6 bits (187), Expect = 7e-15, Method: Composition-based stats.
Identities = 51/177 (29%), Positives = 87/177 (49%), Gaps = 3/177 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
+L GP G++ + + + + + S V TTR R E G +YHFV + F + A
Sbjct 8 VLSGPSGVGKDTVVAAVRERHPEVWVS-VSATTRPPRPGETDGVEYHFVDAEEFARMVKA 66
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
G+F+EH F + YGT + + + +G CLL + + +R++ + +F+APP+
Sbjct 67 GEFVEHAMFAGHAYGTPRRPLLERLAAGVPCLLEIELLGARQVRSAMPQARFVFLAPPTF 126
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
+ L L G PE + +++ R +E FD IVN D+ A L+ L+
Sbjct 127 DELVRRLTGRGTE-SPEVIARRLDRAR-IELAAETEFDDVIVNDDVRSAAARLVALM 181
>sp|Q47R17|KGUA_THEFY Guanylate kinase OS=Thermobifida fusca (strain
YX) OX=269800 GN=gmk PE=3 SV=1
Length=196
Score = 77.0 bits (188), Expect = 8e-15, Method: Composition-based stats.
Identities = 56/187 (30%), Positives = 92/187 (49%), Gaps = 3/187 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
KR +L GP G++ + + L + + + S V TTR R E G +Y+FV F+
Sbjct 13 KRLTVLSGPSGVGKSTVVKELRRRRPEVWLS-VSVTTRPPRPGETDGVEYYFVDDAEFDR 71
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+A + +E EF N YGT + V + + +G+ LL + + +R + +++F+A
Sbjct 72 LVAENELLEWAEFAGNRYGTPREPVLKRLAAGQPVLLEIDLNGARQVRANMPDAFLVFLA 131
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS E L L G PE ++ +E R +E FD +VN+ + + ELL L
Sbjct 132 PPSWEELVRRLTGRGTE-SPEVIQRRLETAR-IELAAEKEFDVTLVNTSVHEVCDELLAL 189
Query 659 INKLDTE 665
I T+
Sbjct 190 IAAPSTQ 196
>sp|Q11HG8|KGUA_CHESB Guanylate kinase OS=Chelativorans sp. (strain
BNC1) OX=266779 GN=gmk PE=3 SV=1
Length=218
Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 54/193 (28%), Positives = 92/193 (48%), Gaps = 20/193 (10%)
Query 478 RKRPIILI--GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
R+R ++L+ P G++ + + L+ + + F +V TTR RR E+ G YHF +++
Sbjct 11 RRRGVMLVLSSPSGAGKSTIARSLLENDHE-FELSVSVTTRPRRPSEIEGVHYHFKTQRD 69
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI- 594
FE G +E E N YGT V + I G+ L + Q LR +
Sbjct 70 FEMMRDGGDLLEWAEVHGNCYGTPRGPVERAIAGGRDMLFDIDWQGAAQLREKMPDDIVS 129
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY-------FDTAIVNSD 647
+FI PP+ + L A L + + E+ EIIE+ N H+ +D ++N D
Sbjct 130 VFILPPTMKELLARLTR-----RAEDTPEIIER----RLRNAHHEIEQWRDYDYVVINDD 180
Query 648 LDKAYQELLRLIN 660
LD+A+ + +++
Sbjct 181 LDRAFASVRAIVS 193
>sp|Q28PK5|KGUA_JANSC Guanylate kinase OS=Jannaschia sp. (strain
CCS1) OX=290400 GN=gmk PE=3 SV=1
Length=218
Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 55/184 (30%), Positives = 87/184 (47%), Gaps = 11/184 (6%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
IIL P G++ L +RLM + + + +V TTR R E G Y F+ F++ ++
Sbjct 13 IILSSPSGAGKSTLARRLMAWD-ETLSFSVSATTRQARPGEEDGVHYRFLPEAEFKSLVS 71
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI--IFIAP 599
+G+ +EH N YG+ + V Q I +G L + Q + +RNSDL + IFI P
Sbjct 72 SGQMLEHAHVFGNFYGSPMAPVSQAIEAGHDVLFDIDWQGAQQIRNSDLGKHTLSIFILP 131
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREM---EQNNGHYFDTAIVNSDLDKAYQELL 656
PS L+ L ++ ++IEK E + +D +VN DL + L
Sbjct 132 PSIPELKRRLESRAQDSD-----DVIEKRMRKSWDEISRWDAYDYVLVNDDLSVTEERLK 186
Query 657 RLIN 660
+I
Sbjct 187 TIIT 190
>sp|Q182S8|KGUA_CLOD6 Guanylate kinase OS=Clostridioides difficile
(strain 630) OX=272563 GN=gmk PE=3 SV=1
Length=205
Score = 76.6 bits (187), Expect = 1e-14, Method: Composition-based stats.
Identities = 49/179 (27%), Positives = 88/179 (49%), Gaps = 3/179 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ GP G+ + + L+ KE D +V TTR R EV G +Y F+S++ FE I
Sbjct 9 LVVSGPSGAGKGTICKELL-KENDTIKLSVSATTRKPRTGEVDGVNYFFISKEKFEEMIE 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+F+E+ + N YGT ++ + + G+ LL + Q K ++ + IF+ PPS
Sbjct 68 KGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLEIEMQGAKQIKEVCPEGVFIFVLPPS 127
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
E L+ + G + E + E++ +D I N D+ + +E+ +I+
Sbjct 128 LEELKNRIVGRGTETEAEIEKRFSCAYEEIKMIKD--YDYFIFNEDVKTSAKEIEGIIS 184
>sp|Q0BL54|KGUA_FRATO Guanylate kinase OS=Francisella tularensis
subsp. holarctica (strain OSU18) OX=393011 GN=gmk PE=3 SV=1
Length=190
Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 53/181 (29%), Positives = 92/181 (51%), Gaps = 5/181 (3%)
Query 482 IILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
I+ P G++ L + + + KD +A A+ HTTR R E+ R+Y+FV+ FE
Sbjct 6 FIISAPSGAGKSSLLKAFLATDIGKDNYAVAISHTTREPRVGEINSREYYFVTVAEFEQL 65
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN-SDLKPYIIFIA 598
++ FIE+ + KN YGTS + +++ GK +L + Q + R + IFI
Sbjct 66 LSQDGFIEYAKVFKNYYGTSKAELDRLLALGKNIILEINWQGAQQTRAIYGDRAKSIFIL 125
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS + LR L K + K E + +E+ + E ++ +D +VN D ++ ++L +
Sbjct 126 PPSLDELRKRLEKRNTDSK-ETIDYRMEQVQS-EISHADEYDYLLVNDDFSQSLEQLCKY 183
Query 659 I 659
Sbjct 184 F 184
>sp|Q255A8|KGUA_CHLFF Guanylate kinase OS=Chlamydia felis (strain
Fe/C-56) OX=264202 GN=gmk PE=3 SV=1
Length=204
Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 53/170 (31%), Positives = 80/170 (47%), Gaps = 3/170 (2%)
Query 486 GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKF 545
P G+ L + L + D F V TTRS R +EV G DY+FVS++ F + +G F
Sbjct 25 APAGAGKTTLVRMLAEEFPDSFQKTVSLTTRSPRPEEVHGVDYYFVSQEEFLKRLDSGDF 84
Query 546 IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERL 605
+E YGTS + ++ SGK + + + LR S + IFI+ PS E L
Sbjct 85 LEWVALFGEYYGTSRLEIDKIWKSGKHAIAVIDVEGALALR-SKIPTVTIFISAPSLEEL 143
Query 606 RALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
L G + + + +EQ F+ I+N DL+K+Y+ L
Sbjct 144 ERRLKHRGSEQDAQRQERL--QHSLIEQAASSKFEYVIINDDLEKSYEIL 191
>sp|Q2LQ62|KGUA_SYNAS Guanylate kinase OS=Syntrophus aciditrophicus
(strain SB) OX=56780 GN=gmk PE=3 SV=1
Length=207
Score = 76.3 bits (186), Expect = 2e-14, Method: Composition-based stats.
Identities = 55/174 (32%), Positives = 87/174 (50%), Gaps = 4/174 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L G+ +R R+ + +V +TTR+ R EV G+DY FV+ F I
Sbjct 13 IVLSAASGTGKTSIR-RIFLERCPEVQFSVSYTTRTARPGEVDGQDYFFVTETDFRERID 71
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+F E E YGTS + +V+ G+ +L + + KTL+ + +F+ PPS
Sbjct 72 QGEFAEWEENYGRYYGTSGKVMTRVLEQGRDMILDIEPRGAKTLKKNYQGGIYVFVLPPS 131
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
L+A L K G++ E+R+ ++K RE E +D I N L+KA + L
Sbjct 132 LAELKARLRKRGESEA--EIRKRLDKVRE-EIAEARGYDYVIFNDSLEKAVERL 182
>sp|Q1B9F6|KGUA_MYCSS Guanylate kinase OS=Mycobacterium sp. (strain
MCS) OX=164756 GN=gmk PE=3 SV=1
Length=198
Score = 75.9 bits (185), Expect = 2e-14, Method: Composition-based stats.
Identities = 56/183 (31%), Positives = 92/183 (50%), Gaps = 7/183 (4%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
R ++L GP G++ + + L + D + S V TTR+ R EV G DY FV+ +AF+
Sbjct 9 RVVVLSGPSAVGKSTVVRCLRERIPDLYFS-VSATTRAPRPGEVDGVDYSFVTPEAFQQL 67
Query 540 IAAGKFIEHGEFEKNLY--GTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I G +E E L+ GT VR+ +G+ L+ + + ++ + + +F+
Sbjct 68 IDDGALLEWAEIHGGLHRSGTPARPVREATVAGRPVLIEVDLAGARAVKQAMPEALSVFL 127
Query 598 APPSQERL-RALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
APPS E L R L+ + + P R +T Q++ FD +VNS L+ A EL+
Sbjct 128 APPSWEVLERRLVGRGTETPDVMSRRLDTARTELAAQSD---FDVVVVNSQLESACSELV 184
Query 657 RLI 659
L+
Sbjct 185 SLL 187
>sp|O84033|KGUA_CHLTR Guanylate kinase OS=Chlamydia trachomatis
(strain D/UW-3/Cx) OX=272561 GN=gmk PE=3 SV=1
Length=205
Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 59/175 (34%), Positives = 81/175 (46%), Gaps = 5/175 (3%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+ P G+ L L + D F V TTRS R EV G DY FVS F+ +
Sbjct 21 FIISAPAGAGKTTLTHMLQREFPDAFEKTVSSTTRSARPGEVHGVDYLFVSEDDFKQSLD 80
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
F+E YGTS + +V+ GK C+ + Q L+ + IFI PS
Sbjct 81 REDFLEWVFLFGTYYGTSKAEISRVLQKGKHCIAVIDVQGALALKK-QMPAVTIFIQAPS 139
Query 602 QERL-RALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
QE L R L A++ + K + +E +E + +E FD +VN DL AYQ L
Sbjct 140 QEELERRLNARDSE--KDFQKKERLEHS-AVEIAAASEFDYVVVNDDLITAYQVL 191
>sp|Q3KMZ2|KGUA_CHLTA Guanylate kinase OS=Chlamydia trachomatis
serovar A (strain ATCC VR-571B / DSM 19440 / HAR-13) OX=315277
GN=gmk PE=3 SV=1
Length=205
Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 59/175 (34%), Positives = 81/175 (46%), Gaps = 5/175 (3%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+ P G+ L L + D F V TTRS R EV G DY FVS F+ +
Sbjct 21 FIISAPAGAGKTTLTHMLQREFPDAFEKTVSSTTRSARPGEVHGVDYLFVSEDDFKQSLD 80
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
F+E YGTS + +V+ GK C+ + Q L+ + IFI PS
Sbjct 81 REDFLEWVFLFGTYYGTSKAEISRVLQKGKHCIAVIDVQGALALKK-QMPAVTIFIQAPS 139
Query 602 QERL-RALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
QE L R L A++ + K + +E +E + +E FD +VN DL AYQ L
Sbjct 140 QEELERRLNARDSE--KDFQKKERLEHS-AVEIAAASEFDYVVVNDDLITAYQVL 191
>sp|Q6HEU4|KGUA_BACHK Guanylate kinase OS=Bacillus thuringiensis
subsp. konkukian (strain 97-27) OX=281309 GN=gmk PE=3 SV=2
Length=205
Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 48/138 (35%), Positives = 69/138 (50%), Gaps = 0/138 (0%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+L GP G+ +R+ L + E RF ++ TTR R+ EV G DY F R+
Sbjct 3 SRRGLLIVLSGPSGVGKGTVRKELFSHEDTRFQYSISVTTRKPREGEVDGVDYFFKEREE 62
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I K +E EF N YGT ID V + + GK L + Q ++ + + I
Sbjct 63 FEEMIRNEKLLEWAEFVGNYYGTPIDYVEKTLQEGKDVFLEIEVQGAIQVKKAFPEGVFI 122
Query 596 FIAPPSQERLRALLAKEG 613
F+APPS L+ + G
Sbjct 123 FLAPPSLSELKNRIVGRG 140
>sp|Q636F5|KGUA_BACCZ Guanylate kinase OS=Bacillus cereus (strain
ZK / E33L) OX=288681 GN=gmk PE=3 SV=2
Length=205
Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 48/138 (35%), Positives = 69/138 (50%), Gaps = 0/138 (0%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+L GP G+ +R+ L + E RF ++ TTR R+ EV G DY F R+
Sbjct 3 SRRGLLIVLSGPSGVGKGTVRKELFSHEDTRFQYSISVTTRKPREGEVDGVDYFFKEREE 62
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I K +E EF N YGT ID V + + GK L + Q ++ + + I
Sbjct 63 FEEMIRNEKLLEWAEFVGNYYGTPIDYVEKTLQEGKDVFLEIEVQGAIQVKKAFPEGVFI 122
Query 596 FIAPPSQERLRALLAKEG 613
F+APPS L+ + G
Sbjct 123 FLAPPSLSELKNRIVGRG 140
>sp|Q732K0|KGUA_BACC1 Guanylate kinase OS=Bacillus cereus (strain
ATCC 10987 / NRS 248) OX=222523 GN=gmk PE=3 SV=2
Length=205
Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 48/138 (35%), Positives = 69/138 (50%), Gaps = 0/138 (0%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+L GP G+ +R+ L + E RF ++ TTR R+ EV G DY F R+
Sbjct 3 SRRGLLIVLSGPSGVGKGTVRKELFSHEDTRFQYSISVTTRKPREGEVDGVDYFFKEREE 62
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I K +E EF N YGT ID V + + GK L + Q ++ + + I
Sbjct 63 FEEMIRNEKLLEWAEFVGNYYGTPIDYVEKTLQEGKDVFLEIEVQGAIQVKKAFPEGVFI 122
Query 596 FIAPPSQERLRALLAKEG 613
F+APPS L+ + G
Sbjct 123 FLAPPSLSELKNRIVGRG 140
>sp|Q81WG7|KGUA_BACAN Guanylate kinase OS=Bacillus anthracis OX=1392
GN=gmk PE=3 SV=1
Length=205
Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 48/138 (35%), Positives = 69/138 (50%), Gaps = 0/138 (0%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+L GP G+ +R+ L + E RF ++ TTR R+ EV G DY F R+
Sbjct 3 SRRGLLIVLSGPSGVGKGTVRKELFSHEDTRFQYSISVTTRKPREGEVDGVDYFFKEREE 62
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I K +E EF N YGT ID V + + GK L + Q ++ + + I
Sbjct 63 FEEMIRNEKLLEWAEFVGNYYGTPIDYVEKTLQEGKDVFLEIEVQGAIQVKKAFPEGVFI 122
Query 596 FIAPPSQERLRALLAKEG 613
F+APPS L+ + G
Sbjct 123 FLAPPSLSELKNRIVGRG 140
>sp|Q2A2K6|KGUA_FRATH Guanylate kinase OS=Francisella tularensis
subsp. holarctica (strain LVS) OX=376619 GN=gmk PE=3 SV=1
Length=190
Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 53/181 (29%), Positives = 92/181 (51%), Gaps = 5/181 (3%)
Query 482 IILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
I+ P G++ L + + + KD +A A+ HTTR R E+ R+Y+FV+ FE
Sbjct 6 FIISAPSGAGKSSLLKAFLATDIGKDNYAVAISHTTREPRVGEINSREYYFVTVAEFEQL 65
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN-SDLKPYIIFIA 598
++ FIE+ + KN YGTS + +++ GK +L + Q + R + IFI
Sbjct 66 LSQDGFIEYAKVFKNYYGTSKAELDRLLALGKNIILEIDWQGAQQTRAIYGDRAKSIFIL 125
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS + LR L K + K E + +E+ + E ++ +D +VN D ++ ++L +
Sbjct 126 PPSLDELRKRLEKRNTDSK-ETIDYRMEQVQS-EISHADEYDYLLVNDDFSQSLEQLCKY 183
Query 659 I 659
Sbjct 184 F 184
>sp|P44310|KGUA_HAEIN Guanylate kinase OS=Haemophilus influenzae
(strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=gmk
PE=3 SV=1
Length=208
Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 56/177 (32%), Positives = 87/177 (49%), Gaps = 8/177 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
IL P G++ L L+ + + +V HTTR+ R EV G Y+FVS++ FE+ I
Sbjct 8 ILSAPSGAGKSSLISALLASDSSTQKMVSVSHTTRAPRPGEVEGVHYYFVSKEEFESLIE 67
Query 542 AGKFIEHGE-FEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
F+E+ + F N YGTS+ ++ + + G L + Q + +R IFI PP
Sbjct 68 QDLFLEYAKVFGGNYYGTSLPAIEENLAKGIDVFLDIDWQGAQQIRKKVPSVKSIFILPP 127
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQEL 655
S L L G++ EE+ I E+ + HY +D IVN D +K ++L
Sbjct 128 SLPELERRLIGRGQD--SEEV--IAERMSKAMSEISHYDEYDYVIVNDDFEKTLKDL 180
>sp|Q97ID0|KGUA_CLOAB Guanylate kinase OS=Clostridium acetobutylicum
(strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM
B-1787) OX=272562 GN=gmk PE=3 SV=1
Length=209
Score = 75.9 bits (185), Expect = 2e-14, Method: Composition-based stats.
Identities = 49/178 (28%), Positives = 92/178 (52%), Gaps = 4/178 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I++ GP G+ + + LM +++ F +V TTR R++EV G+ Y+F++ F++ I+
Sbjct 8 IVISGPSGAGKGTICKALMKEQQ--FWLSVSATTREPREKEVEGKSYYFLTVDEFKSKIS 65
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
F+E+ E N YGT SV + I++G+ +L + Q ++ + + IFI PPS
Sbjct 66 EDGFLEYAEVYGNYYGTPKKSVCEKIDNGENVILEIDIQGALKVKENYPEGVFIFILPPS 125
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
E L+ + G + + K+ E N ++ AI+N ++ A ++ +I
Sbjct 126 MEELKKRIIGRGSETEKSLMTRF--KSAYKEINYVSKYNYAIINDTVENAVTKINSII 181
>sp|Q8R9S6|KGUA_CALS4 Guanylate kinase OS=Caldanaerobacter subterraneus
subsp. tengcongensis (strain DSM 15242 / JCM 11007
/ NBRC 100824 / MB4) OX=273068 GN=gmk PE=3 SV=1
Length=206
Score = 75.5 bits (184), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 50/178 (28%), Positives = 88/178 (49%), Gaps = 3/178 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I++ GP G+ + + L+ KEKD ++ TTR R EV G++Y F S + F+ I
Sbjct 10 IVISGPSGAGKGTICKALIEKEKD-LKLSISATTRQPRAGEVDGKNYFFKSEEEFKRMIE 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
F+E + + YGT + V + + G +L + Q ++ + IFI PPS
Sbjct 69 EDAFLEWAKVYDHYYGTPKEFVLKNLEEGNDVVLEIDIQGALKVKEKFPEGVFIFILPPS 128
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
E LR + K G + E ++ K+ E N ++ ++N D+D+A +++ +I
Sbjct 129 MEELRNRIKKRGTESEEEIIKRF--KSAYEELNYVSKYNYVVINDDVDRAVEKIRAII 184
>sp|Q9CCQ7|KGUA_MYCLE Guanylate kinase OS=Mycobacterium leprae
(strain TN) OX=272631 GN=gmk PE=3 SV=1
Length=210
Score = 75.5 bits (184), Expect = 3e-14, Method: Composition-based stats.
Identities = 58/194 (30%), Positives = 92/194 (47%), Gaps = 13/194 (7%)
Query 472 YHQPANRKRPIILIGPQNCGQNE----LRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRD 527
+ + ++ R ++L GP G++ LR+R+ N +V TTR R E+ G D
Sbjct 16 WSEQTDKGRVVVLSGPSAVGKSTVVRCLRERVSN-----LHFSVSATTREPRPDEMDGVD 70
Query 528 YHFVSRQAFEADIAAGKFIEHGEFEKNLY--GTSIDSVRQVINSGKICLLSLRTQSLKTL 585
YHFVS F+ I G +E E ++ GT + VR +G L+ + + +
Sbjct 71 YHFVSPARFQQLIDQGALLEWAEIHGGMHRSGTLAEPVRVAAAAGFPVLIEVDLAGARAV 130
Query 586 RNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVN 645
+ + + +F+APPS E L A L G PE +R +E R +E FD +VN
Sbjct 131 KKAMPEAIAVFLAPPSWEDLEARLVGRGTE-TPEAIRRRLETAR-IELAAQDDFDEVVVN 188
Query 646 SDLDKAYQELLRLI 659
L+ A EL+ L+
Sbjct 189 RRLESACAELVSLL 202
>sp|Q5E8P5|KGUA_ALIF1 Guanylate kinase OS=Aliivibrio fischeri
(strain ATCC 700601 / ES114) OX=312309 GN=gmk PE=3 SV=1
Length=207
Score = 75.5 bits (184), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 51/180 (28%), Positives = 79/180 (44%), Gaps = 7/180 (4%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDR-FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+ P G++ L L+ +V HTTR R E G YHF+ ++ FE I
Sbjct 8 IVSAPSGAGKSSLISALLESNPTYAMKVSVSHTTRGMRPGETDGVHYHFIQKEHFEELIQ 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+F+E+ E N YGTS + + ++ G L + Q + +R +FI PPS
Sbjct 68 KGEFLEYAEVFGNYYGTSRVWIEETLDKGIDVFLDIDWQGARQIREQMPLAKSVFILPPS 127
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLRLI 659
L L G++ I ++ E + HY +D I+N D D A + +I
Sbjct 128 NGELERRLNARGQDSDA----VIAKRMSEAKSEISHYDEYDYVIINDDFDTAQMDFRSII 183
>sp|Q9X215|KGUA_THEMA Guanylate kinase OS=Thermotoga maritima
(strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
OX=243274 GN=gmk PE=3 SV=1
Length=207
Score = 75.5 bits (184), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 47/178 (26%), Positives = 85/178 (48%), Gaps = 3/178 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++ GP G+ + + ++ K D +V TTR +R E G+DY F++ + F +
Sbjct 6 FVICGPSGAGKTSIIKEVL-KRLDNVVFSVSCTTRPKRPHEEDGKDYFFITEEEFLKRVE 64
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+F+E +LYGT V IN GK +L + Q +++ I++APPS
Sbjct 65 RGEFLEWARVHGHLYGTLRSFVESHINEGKDVVLDIDVQGALSVKKKYSNTVFIYVAPPS 124
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
LR + K G + + L + E+ + FD +VN +L+ A + ++ ++
Sbjct 125 YADLRERILKRGTEKEADVLVRLENAKWELMFMDE--FDYIVVNENLEDAVEMVVSIV 180
>sp|Q65RR5|KGUA_MANSM Guanylate kinase OS=Mannheimia succiniciproducens
(strain MBEL55E) OX=221988 GN=gmk PE=3 SV=1
Length=208
Score = 75.1 bits (183), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 53/181 (29%), Positives = 85/181 (47%), Gaps = 8/181 (4%)
Query 483 ILIGPQNCGQNELRQRLMNKEK-DRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
IL P G++ L L+ +++ + +V HTTR R E G YHFVS + FE I
Sbjct 8 ILSAPSGAGKSSLISALLEQDQANTMMVSVSHTTRQPRPGEENGVHYHFVSVEEFELLIN 67
Query 542 AGKFIEHGE-FEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
G F+E+ + F N YGTS+ ++ + + G L + Q + +R IFI PP
Sbjct 68 EGAFLEYAKVFGGNYYGTSLPTIEKNLAQGIDVFLDIDWQGAQQIRKKVPSVKSIFILPP 127
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLRL 658
S L L G++ I ++ + HY +D I+N D +A +L+ +
Sbjct 128 SLAELEKRLIGRGQDSA----EVIADRMSKAMDEISHYNEYDYVIINDDFTRALADLVHI 183
Query 659 I 659
+
Sbjct 184 L 184
>sp|Q4UK55|KGUA_RICFE Guanylate kinase OS=Rickettsia felis (strain
ATCC VR-1525 / URRWXCal2) OX=315456 GN=gmk PE=3 SV=1
Length=192
Score = 74.7 bits (182), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 51/183 (28%), Positives = 90/183 (49%), Gaps = 3/183 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N+ IIL P G++ L + L+ K + ++ TTR R EV G +Y+F ++ F
Sbjct 5 NKGLIIILSSPSGTGKSSLAKALL-KIDNNLRLSISATTRKPRLGEVEGINYYFKTKLEF 63
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
E + KF+E+ + N YGT + V ++N G L + Q K+++ + IF
Sbjct 64 EELVKQNKFLEYAKIYDNYYGTPKEYVEMLLNQGLDVLFDIDWQGAKSIKKNATNVVAIF 123
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS E L L + EE ++ ++ + E ++ + +D I N D D+ +++
Sbjct 124 ILPPSIEILEQRLRNRATD--NEEAIKLRMQSAQNEMSHANEYDYVITNDDFDQTLKKIH 181
Query 657 RLI 659
+I
Sbjct 182 EII 184
>sp|Q4QJK3|KGUA_HAEI8 Guanylate kinase OS=Haemophilus influenzae
(strain 86-028NP) OX=281310 GN=gmk PE=3 SV=1
Length=208
Score = 75.1 bits (183), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 56/177 (32%), Positives = 87/177 (49%), Gaps = 8/177 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
IL P G++ L L+ + + +V HTTR+ R EV G Y+FVS++ FE+ I
Sbjct 8 ILSAPSGAGKSSLISALLASDSSTQKMVSVSHTTRAPRPGEVEGVHYYFVSKEEFESLIE 67
Query 542 AGKFIEHGE-FEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
F+E+ + F N YGTS+ ++ + + G L + Q + +R IFI PP
Sbjct 68 QDLFLEYAKVFGGNYYGTSLPAIEENLAKGIDVFLDIDWQGAQQIRKKVPSVKSIFILPP 127
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQEL 655
S L L G++ EE+ I E+ + HY +D IVN D +K ++L
Sbjct 128 SLPELERRLIGRGQD--SEEV--IAERMSKAISEISHYDEYDYVIVNDDFEKTLKDL 180
>sp|Q2NQS9|KGUA_SODGM Guanylate kinase OS=Sodalis glossinidius
(strain morsitans) OX=343509 GN=gmk PE=3 SV=1
Length=207
Score = 75.1 bits (183), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 58/183 (32%), Positives = 89/183 (49%), Gaps = 13/183 (7%)
Query 483 ILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ + D S + HTTR+ R E G+ Y FV FE I
Sbjct 8 IVSAPSGAGKSSLIQALLKTQPLYDTQVS-ISHTTRAMRPGEAHGQHYFFVPVAEFEHMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
A F+E+ N YGTS ++++QV+ +G L + Q + +R IF+ PP
Sbjct 67 AEDAFLEYARVFDNYYGTSREAIQQVLATGVDVFLDIDWQGAQQIRAKMPDARSIFVLPP 126
Query 601 SQERLRALLAKEGKNPKPEEL--REIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELL 656
S+E L L G++ EE+ R + + EM H+ +D IVN D + A +L
Sbjct 127 SKEELDRRL--RGRDQDSEEVIGRRMAQAVAEMT----HFAEYDYLIVNDDFNTALLDLK 180
Query 657 RLI 659
+I
Sbjct 181 TII 183
>sp|Q822M8|KGUA_CHLCV Guanylate kinase OS=Chlamydia caviae (strain
ATCC VR-813 / DSM 19441 / 03DC25 / GPIC) OX=227941 GN=gmk
PE=3 SV=1
Length=204
Score = 75.1 bits (183), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 55/188 (29%), Positives = 92/188 (49%), Gaps = 10/188 (5%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
P+ + + P G+ L + L + D F + TTR+ R +EV+G DY FVS++
Sbjct 14 PSCAPKLFTISAPAGAGKTTLVRMLAQEFPDSFQKTLSLTTRAPRPEEVSGIDYWFVSQE 73
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
F+ + + F+E YGTS + ++ SGK + + + +L+ S +
Sbjct 74 EFKQRLDSNNFLEWVLLFGEYYGTSRLEIDEIWKSGKHAVAVIDVEGALSLK-SKIPTVT 132
Query 595 IFIAPPSQERLRALLAKEGK---NPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
IFI+ PSQE L L G + + E L+ + +EQ + F+ I+N DL K+
Sbjct 133 IFISAPSQEELERRLKYRGSEQDSQRQERLQHSL-----IEQAASNQFEYVIINDDLQKS 187
Query 652 YQELLRLI 659
Y E+L+ I
Sbjct 188 Y-EILKSI 194
>sp|Q7N9P2|KGUA_PHOLL Guanylate kinase OS=Photorhabdus laumondii
subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01) OX=243265
GN=gmk PE=3 SV=1
Length=207
Score = 75.1 bits (183), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 59/184 (32%), Positives = 89/184 (48%), Gaps = 15/184 (8%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFAS--AVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ K + + + +V HTTR+ R E G Y F++ +AF I
Sbjct 8 IVSAPSGAGKSSLIQALL-KTQPLYDTQVSVSHTTRAMRPGENQGEHYFFITEEAFRQMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
+F+EH N YGTS + + + SG L + Q + +R IFI PP
Sbjct 67 DNNEFLEHARVFDNYYGTSRKVIEETLASGVDVFLDIDWQGAQQIRKKMPSARSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNG---HY--FDTAIVNSDLDKAYQEL 655
S+E L L G++ + +IIEK M+Q HY +D IVN D + A +L
Sbjct 127 SKEELCRRLRGRGQDSE-----DIIEK--RMDQAVAEMVHYNEYDYLIVNDDFNTALADL 179
Query 656 LRLI 659
+I
Sbjct 180 HTII 183
>sp|Q6AJ91|KGUA_DESPS Guanylate kinase OS=Desulfotalea psychrophila
(strain LSv54 / DSM 12343) OX=177439 GN=gmk PE=3 SV=1
Length=203
Score = 74.7 bits (182), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 57/184 (31%), Positives = 83/184 (45%), Gaps = 4/184 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N+ + ++ P G+ + R+M R ++ HTTR+ R E G DYHFV ++ F
Sbjct 2 NKGKLFVISAPSGAGKTTILGRVM-ANVGRLNFSISHTTRTARPGEQDGVDYHFVEQEDF 60
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS-DLKPYII 595
G F+E KN YGTS ++V ++ G +L + Q L S L I
Sbjct 61 IEMQEKGIFLESAYVHKNYYGTSREAVMAQLSEGVDVVLDIDVQGATILMESASLPATYI 120
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FIAPP L L K G + EE ++ E + +D IVN DL +A L
Sbjct 121 FIAPPDLSVLEERLRKRGSD--SEETIKLRMGNAAGEMLSSRKYDYLIVNDDLAQASTLL 178
Query 656 LRLI 659
+I
Sbjct 179 KSII 182
>sp|Q0AXK8|KGUA_SYNWW Guanylate kinase OS=Syntrophomonas wolfei
subsp. wolfei (strain DSM 2245B / Goettingen) OX=335541 GN=gmk
PE=3 SV=1
Length=195
Score = 74.3 bits (181), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 53/184 (29%), Positives = 87/184 (47%), Gaps = 4/184 (2%)
Query 477 NRKRPIILI-GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
NRK + +I GP G+ L++ L+++ KD ++ TTR R EV G+ Y FV +
Sbjct 2 NRKGILFVISGPSGVGKGTLKKALLDQTKD-LNLSISATTRPARLGEVHGQHYFFVDQAK 60
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F I F+E + NLYGT V + G+ LL + Q ++ I
Sbjct 61 FREMIEQDAFLEWAQVYSNLYGTPRGFVLNHLQQGRDVLLEIDIQGALQVKEKMPSGVFI 120
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PP+ E L L G++ + + E++ + Y+D +VN +D+A Q++
Sbjct 121 FIYPPNLEELAFRLVSRGQDSQDSIEARLAACENELKHID--YYDYLVVNDKIDRALQKI 178
Query 656 LRLI 659
+I
Sbjct 179 TAII 182
>sp|Q2W9C3|KGUA_MAGSA Guanylate kinase OS=Magnetospirillum magneticum
(strain AMB-1 / ATCC 700264) OX=342108 GN=gmk PE=3 SV=1
Length=214
Score = 75.1 bits (183), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 51/180 (28%), Positives = 91/180 (51%), Gaps = 6/180 (3%)
Query 475 PANRKRPIILI--GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVS 532
P +R ++L+ P G+ + + L+ ++ +V TTR+ R EV G+DYHFV+
Sbjct 6 PTVSRRGLMLVMSSPSGAGKTTISRALLERDP-AIGMSVSATTRAPRPGEVDGKDYHFVT 64
Query 533 RQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTL-RNSDLK 591
+ F + +F+EH N YGT V +++ SG+ L + Q + + +N+
Sbjct 65 VEKFHEMVEKREFLEHARVFDNFYGTPRGPVDEILRSGRDVLFDIDWQGTQQMAQNARAD 124
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
+F+ PPS E L L ++ E +R+ + K + E ++ +D +VN DLDK+
Sbjct 125 LVSVFVLPPSVEELERRLRGRAQDSD-EVVRKRMAKAGD-EMSHWPEYDYIVVNIDLDKS 182
>sp|Q5NEY6|KGUA_FRATT Guanylate kinase OS=Francisella tularensis
subsp. tularensis (strain SCHU S4 / Schu 4) OX=177416 GN=gmk
PE=3 SV=1
Length=190
Score = 74.3 bits (181), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 51/181 (28%), Positives = 90/181 (50%), Gaps = 5/181 (3%)
Query 482 IILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
I+ P G++ L + + + KD +A A+ HTTR R E+ R+Y+FV+ FE
Sbjct 6 FIVSAPSGAGKSSLLKAFLATDIGKDNYAVAISHTTREPRVGEINSREYYFVTVAEFEQL 65
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN-SDLKPYIIFIA 598
++ FIE+ + KN YGTS + +++ GK +L + Q + R + IFI
Sbjct 66 LSQDGFIEYAKVFKNYYGTSKAELDRLLALGKNIILEIDWQGAQQTRAIYGDRAKSIFIL 125
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS + LR L K +N +E + + + E ++ +D +VN D ++ ++ +
Sbjct 126 PPSLDELRKRLEK--RNTDSKETIDYRMEQAQSEISHADEYDYLLVNDDFSQSLEQFCKY 183
Query 659 I 659
Sbjct 184 F 184
>sp|Q14GD9|KGUA_FRAT1 Guanylate kinase OS=Francisella tularensis
subsp. tularensis (strain FSC 198) OX=393115 GN=gmk PE=3
SV=1
Length=190
Score = 74.3 bits (181), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 51/181 (28%), Positives = 90/181 (50%), Gaps = 5/181 (3%)
Query 482 IILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
I+ P G++ L + + + KD +A A+ HTTR R E+ R+Y+FV+ FE
Sbjct 6 FIVSAPSGAGKSSLLKAFLATDIGKDNYAVAISHTTREPRVGEINSREYYFVTVAEFEQL 65
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN-SDLKPYIIFIA 598
++ FIE+ + KN YGTS + +++ GK +L + Q + R + IFI
Sbjct 66 LSQDGFIEYAKVFKNYYGTSKAELDRLLALGKNIILEIDWQGAQQTRAIYGDRAKSIFIL 125
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS + LR L K +N +E + + + E ++ +D +VN D ++ ++ +
Sbjct 126 PPSLDELRKRLEK--RNTDSKETIDYRMEQAQSEISHADEYDYLLVNDDFSQSLEQFCKY 183
Query 659 I 659
Sbjct 184 F 184
>sp|Q39T72|KGUA_GEOMG Guanylate kinase OS=Geobacter metallireducens
(strain ATCC 53774 / DSM 7210 / GS-15) OX=269799 GN=gmk
PE=3 SV=1
Length=203
Score = 74.3 bits (181), Expect = 7e-14, Method: Composition-based stats.
Identities = 51/177 (29%), Positives = 83/177 (47%), Gaps = 3/177 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I+ P G+ L + +++ +V +TTR R EV G+DY+F+S F + +
Sbjct 9 IISAPSGAGKTTLCKEIIDIFP-HLRHSVSYTTRQPRAGEVHGKDYYFISMDEFRSMVDK 67
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
G+F E E N YGTSI ++ + +G +L + Q + L+ IFI PPS
Sbjct 68 GEFAEWAEVHGNCYGTSIRTLEECRITGIDLILDIDIQGARQLKERYEGGVYIFILPPSY 127
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
E LR L + R I E+ ++ ++D IVN +A +EL ++
Sbjct 128 EELRRRLNGRSSDSDDVISRRIDAAAGEIRES--RWYDYIIVNDQFSRAVEELKSVV 182
>sp|Q110R6|KGUA_TRIEI Guanylate kinase OS=Trichodesmium erythraeum
(strain IMS101) OX=203124 GN=gmk PE=3 SV=1
Length=186
Score = 73.9 bits (180), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 51/178 (29%), Positives = 82/178 (46%), Gaps = 3/178 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ L L+++ A +V TTRS R EV G+ Y FV F I
Sbjct 7 IVLTGPSGVGKGTLLSCLLHRHPG-LAFSVSVTTRSPRPGEVEGKSYFFVDHDQFREMIE 65
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+ + +E E+ N YGT V + I G+ +L + Q + ++ + IFI PPS
Sbjct 66 SEELLEWAEYAGNFYGTPRVPVIENIEQGRSMILEIELQGARQIQRTFPDALRIFILPPS 125
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
L L G++ + + + T E+E FD +VN ++ Q L +++
Sbjct 126 MAELEERLWGRGQDSEEAITKRLQRATEELEAAT--EFDIQLVNDSIEDTLQNLDKIL 181
>sp|Q24TX4|KGUA_DESHY Guanylate kinase OS=Desulfitobacterium hafniense
(strain Y51) OX=138119 GN=gmk PE=3 SV=1
Length=200
Score = 74.3 bits (181), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 52/177 (29%), Positives = 83/177 (47%), Gaps = 9/177 (5%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L GP G+ L Q L+ ++ + +V TTR R E+ G Y+F SR+ F+ I
Sbjct 9 IVLSGPSGAGKGTLCQELL-RQLPQVKYSVSATTRQPRPGEMDGLHYYFRSREEFQTMIE 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+ +E EF N YGT +V Q I +G +L + Q ++ + IF+ PPS
Sbjct 68 QDQLLEWAEFCGNYYGTPQFAVEQAIQAGNDVILEIEIQGALQVKQRFPQGVFIFVVPPS 127
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY---FDTAIVNSDLDKAYQEL 655
+ L + K G E E+I+K + Y +D +VN ++ A +L
Sbjct 128 MDELSQRIHKRGT-----ESEEVIQKRLQTAARELEYVSEYDYVVVNDEIPLAVDKL 179
>sp|Q0AQC4|KGUA_MARMM Guanylate kinase OS=Maricaulis maris (strain
MCS10) OX=394221 GN=gmk PE=3 SV=1
Length=218
Score = 74.7 bits (182), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 54/182 (30%), Positives = 90/182 (49%), Gaps = 6/182 (3%)
Query 477 NRKRPIILI--GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
R+R ++L P G+ L +RL+++ D S V TTR R EV G+DYHF+S
Sbjct 13 GRRRGVLLALSSPSGAGKTTLSKRLLSQNPDVVLS-VSATTRKPRPGEVDGQDYHFISVD 71
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
F+ I +F E E YGT V + + G+ + + Q + L + +
Sbjct 72 EFKKKIEDDEFFEWAEVFGRYYGTPKTPVMEAVEDGRDVVFDIDWQGAQALAAAAPDDAV 131
Query 595 -IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
+FI PPS L L K G++ E +++ + + ++ E ++ H +D IVN D +A +
Sbjct 132 RVFILPPSLALLEDRLRKRGQD-TTEIIKDRMARAKD-EISHWHEYDYVIVNDDFARALE 189
Query 654 EL 655
+L
Sbjct 190 KL 191
>sp|Q46GV6|KGUA_PROMT Guanylate kinase OS=Prochlorococcus marinus
(strain NATL2A) OX=59920 GN=gmk PE=3 SV=1
Length=186
Score = 73.6 bits (179), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 48/173 (28%), Positives = 85/173 (49%), Gaps = 3/173 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
+L GP G+ + ++++ D + S + TTR R E+ G Y F+ ++ F+ I
Sbjct 9 VLTGPSGVGKGTIVRKILESHSDVWLS-ISATTRQPRSGEIDGEHYFFLEKKQFQEIIDK 67
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
F+E F N YGT V++ I G LL + + + +R S + + IF+APP+
Sbjct 68 DGFLEWASFSNNFYGTPKKIVKEKIEKGTNVLLEIELEGARQIRKSFPEAFQIFLAPPNL 127
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
L + G + E +R+ + E E FD ++N D++KA++E+
Sbjct 128 YELEKRIRGRGTETE-ESIRDRL-SIAEKELIAQKEFDAVVINEDIEKAFKEI 178
>sp|Q7MAK5|KGUA_WOLSU Guanylate kinase OS=Wolinella succinogenes
(strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC
602W) OX=273121 GN=gmk PE=3 SV=1
Length=215
Score = 74.3 bits (181), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 49/152 (32%), Positives = 77/152 (51%), Gaps = 7/152 (5%)
Query 510 AVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINS 569
+V TTR+ R+ E+ G+ YHFVS++ F I F+E E N YGTS +SV +
Sbjct 36 SVSTTTRTPREGEIEGKHYHFVSKEKFLEGIEENFFLEWAEVHGNYYGTSKESVESALAQ 95
Query 570 GKICLLSLRTQSLKTLRNSDLKPYI---IFIAPPSQERLRALLAKEGKNPKPEELREIIE 626
GK+ + + Q + ++ S P + +FI P+Q+ LR L G + K ++
Sbjct 96 GKLVVFDIDIQGHRNIKES--YPELTTSVFITTPTQQELRERLVLRGTDDKETIDLRVMH 153
Query 627 KTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
EM+ FD IVN DL ++ + LL +
Sbjct 154 AYTEMKHIKE--FDFVIVNRDLKESEKLLLSI 183
>sp|P57888|KGUA_PASMU Guanylate kinase OS=Pasteurella multocida
(strain Pm70) OX=272843 GN=gmk PE=3 SV=1
Length=208
Score = 74.3 bits (181), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 55/180 (31%), Positives = 87/180 (48%), Gaps = 7/180 (4%)
Query 483 ILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
IL P G++ L L+N+++D + +V HTTR R E G Y+FVS +AFE+ I
Sbjct 8 ILSAPSGAGKSSLISALLNQQQDNKMMVSVSHTTRQPRPGEQEGVHYYFVSVEAFESLIE 67
Query 542 AGKFIEHGE-FEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
F+E+ + F N YGTS+ ++ + + G L + Q + +R IFI PP
Sbjct 68 QDLFLEYAKVFGGNYYGTSLPAIEENLAKGIDVFLDIDWQGAQQIRQKVPNVKSIFILPP 127
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA---YQELLR 657
S L L G++ + + E+ N +D IVN ++A +Q +LR
Sbjct 128 SLAELERRLIGRGQDSTEVIAARMSKAIDEISHYNE--YDYVIVNDVFEQALADFQAILR 185
>sp|Q2IX83|KGUA_RHOP2 Guanylate kinase OS=Rhodopseudomonas palustris
(strain HaA2) OX=316058 GN=gmk PE=3 SV=1
Length=220
Score = 74.3 bits (181), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 86/175 (49%), Gaps = 4/175 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+L P G+ L R++ E +V TTR +R EV GRDY+FV R F+A +
Sbjct 19 FVLSSPSGAGKTTL-SRMLVDEAPGLRMSVSATTRPKRPGEVDGRDYYFVDRPKFDAMVE 77
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-IFIAPP 600
AG+F+E N YGT V +++G L + Q + LR+ + +FI PP
Sbjct 78 AGEFLEWANVFDNCYGTPRAPVEAALSAGNDVLFDIDWQGTQQLRSRASNDVVSVFILPP 137
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
S + L L ++ E +R ++K + E ++ +D +VN ++ A++ +
Sbjct 138 SVQDLEHRLHTRAQDSD-EVIRGRMKKAGD-EMSHFDAYDYIVVNDNIGVAFESV 190
>sp|Q7MWS7|KGUA_PORGI Guanylate kinase OS=Porphyromonas gingivalis
(strain ATCC BAA-308 / W83) OX=242619 GN=gmk PE=3 SV=1
Length=188
Score = 73.6 bits (179), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 53/185 (29%), Positives = 92/185 (50%), Gaps = 8/185 (4%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
II+ P G++ + +RL+ + ++ T+R+ R +E GR+Y+F+S + F I
Sbjct 5 IIISAPSGTGKSTVIERLLTDRELNLHFSISATSRAPRGEEQNGREYYFLSPEEFRRRIE 64
Query 542 AGKFIEHGE-FEKNLYGTSIDSVRQVINSGKICLLSLRT---QSLKTLRNSDLKPYIIFI 597
A +F+E+ E + YGT V +++ K + + QS+K + IFI
Sbjct 65 ANEFVEYEEVYRDKYYGTLKSEVERILKEEKNVIFDVDVVGAQSIKKYYGD--RALAIFI 122
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS E LR+ L K G + E +++ ++K E E H FD VN DL +++ +
Sbjct 123 LPPSIEELRSRLQKRGTDSM-ETIKQRVDKA-EKEIGYAHLFDLRFVNDDLVTCVEQIRK 180
Query 658 LINKL 662
I +
Sbjct 181 AIAQF 185
>sp|Q6G439|KGUA_BARHE Guanylate kinase OS=Bartonella henselae
(strain ATCC 49882 / DSM 28221 / CCUG 30454 / Houston 1) OX=283166
GN=gmk PE=1 SV=1
Length=222
Score = 74.3 bits (181), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 55/195 (28%), Positives = 97/195 (50%), Gaps = 13/195 (7%)
Query 463 ILTYEEMSLYHQPANRKRPIILI--GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRD 520
++T+ E L + N++R + I P G++ L + L+ K ++ TTR +R
Sbjct 1 MVTFFENELSAKKRNQRRGFLFILSSPSGAGKSTLSRLLLKDGK--LELSISMTTRQKRP 58
Query 521 QEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQ 580
EV G YHF+S++ F+ +FIE E N YGT +SV V+++G+ L + Q
Sbjct 59 SEVDGLHYHFISKKEFKRKRDGNEFIEWAEVHGNYYGTLRESVENVLSTGRDMLFDIDYQ 118
Query 581 SLKTLRNSDLKPYI-IFIAPPSQERLRALLAKEGKNPKPEELREIIE---KTREMEQNNG 636
K L+ + +FI PPS + L + L + + E+ ++II K E +
Sbjct 119 GTKQLQKKMPGDTVSVFILPPSMKELISRLYR-----RAEDSQDIINLRLKNARTEMQHW 173
Query 637 HYFDTAIVNSDLDKA 651
+D I+N +L+++
Sbjct 174 RSYDYVIINENLNQS 188
>sp|P60551|KGUA_GEOSL Guanylate kinase OS=Geobacter sulfurreducens
(strain ATCC 51573 / DSM 12127 / PCA) OX=243231 GN=gmk
PE=3 SV=1
Length=203
Score = 73.9 bits (180), Expect = 1e-13, Method: Composition-based stats.
Identities = 56/179 (31%), Positives = 88/179 (49%), Gaps = 7/179 (4%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
IL P G+ L + +++ + +V +TTR+ R E+ G+DY FVS F I A
Sbjct 9 ILSAPSGAGKTTLCREIIDIFP-QLRHSVSYTTRTPRPGEIHGKDYFFVSMDEFHRMIDA 67
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
+F E E N YGTSI ++ + +G +L + Q + L+ IFI PPS
Sbjct 68 DEFAEWAEVHGNCYGTSIRTLEENRAAGVDLILDIDIQGARQLQERFAGGVYIFILPPSF 127
Query 603 ERLRALLAKEGKNPKPEEL--REIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
E LR L G++ +E+ R I E+ ++ ++D IVN +A +EL +I
Sbjct 128 EELRRRL--NGRSSDSDEVISRRINAAAGEIRES--RWYDYIIVNDQFSRAVEELKSVI 182
>sp|Q1IK22|KGUA_KORVE Guanylate kinase OS=Koribacter versatilis
(strain Ellin345) OX=204669 GN=gmk PE=3 SV=1
Length=233
Score = 74.7 bits (182), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 56/185 (30%), Positives = 90/185 (49%), Gaps = 14/185 (8%)
Query 482 IILIGPQNCGQ----NELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
I+ P G+ NELR + E ++ +TTR+ R E GR+Y FV+R+ F+
Sbjct 6 FIISAPSGSGKSSLVNELRHVVPGLE-----FSISYTTRAPRGSEQNGREYFFVTREKFD 60
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
A +AA +F+EH E YGT+ V + + G +L + Q L+ IFI
Sbjct 61 AMLAADEFLEHAEVFGECYGTAKHFVTEALARGNDLVLDIDVQGAAQLKVKLPDAVGIFI 120
Query 598 APPSQERLRALLAKEGKNPKPEELREIIE---KTREMEQNNGHYFDTAIVNSDLDKAYQE 654
PPS++ L A L + +N E+IE K E N ++D +VN + + A ++
Sbjct 121 LPPSRKELEARLKR--RNLSDHVAPEVIERRLKGAGKEIENFSHYDYILVNDNFETAVEQ 178
Query 655 LLRLI 659
L ++
Sbjct 179 LRAIV 183
>sp|Q7NK59|KGUA_GLOVI Guanylate kinase OS=Gloeobacter violaceus
(strain ATCC 29082 / PCC 7421) OX=251221 GN=gmk PE=3 SV=1
Length=205
Score = 73.9 bits (180), Expect = 1e-13, Method: Composition-based stats.
Identities = 57/188 (30%), Positives = 89/188 (47%), Gaps = 4/188 (2%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
R ++L GP G++ + + + + + S V TTR R EV GRDY F+S FE
Sbjct 18 RLLVLSGPSGVGKDTILREVRERHPGLYVS-VSATTRPPRPGEVDGRDYRFLSAAEFEEW 76
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
IA +E + N YGT V + + G+ +L + Q ++N+ ++FI P
Sbjct 77 IATDDLLEWACYVGNYYGTPKTPVLERLAVGEPVVLEIDVQGALQVKNNFPAAMLVFIRP 136
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
PS E L L G + PE + + + RE E FD +VN L A + + RL+
Sbjct 137 PSLEVLAERLRSRGTD-APEAIERRLARARE-ELALADRFDHQVVNDKLAAAVEAVERLL 194
Query 660 -NKLDTEP 666
++ EP
Sbjct 195 FEEIPDEP 202
>sp|P60553|KGUA_MYCPA Guanylate kinase OS=Mycolicibacterium paratuberculosis
(strain ATCC BAA-968 / K-10) OX=262316 GN=gmk
PE=3 SV=1
Length=223
Score = 74.3 bits (181), Expect = 1e-13, Method: Composition-based stats.
Identities = 61/192 (32%), Positives = 92/192 (48%), Gaps = 13/192 (7%)
Query 474 QPANRKRPIILIGPQNCGQNE----LRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYH 529
+P+ R ++L GP G++ LR+R+ N +V TTR+ R EV G DYH
Sbjct 16 EPSGDGRVVVLSGPSAVGKSTVVRCLRERVPN-----LHFSVSATTRAPRPGEVDGVDYH 70
Query 530 FVSRQAFEADIAAGKFIEHGEFEKNLY--GTSIDSVRQVINSGKICLLSLRTQSLKTLRN 587
FVS F+ I G +E E L+ GT VR + G L+ + + ++
Sbjct 71 FVSPARFQQLIDEGALLEWAEIHSGLHRSGTLAAPVRAAVARGCPVLIEVDLAGARAVKK 130
Query 588 SDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD 647
+ + +F+APPS E L A L G PE + ++ R +E H FD +VNS
Sbjct 131 AMPEALTVFLAPPSWEDLEARLIGRGTE-TPEVIARRLQTAR-VEMAAQHDFDRVVVNSR 188
Query 648 LDKAYQELLRLI 659
L+ A EL+ L+
Sbjct 189 LESACAELVSLL 200
>sp|Q1LQ34|KGUA_CUPMC Guanylate kinase OS=Cupriavidus metallidurans
(strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34) OX=266264
GN=gmk PE=3 SV=1
Length=216
Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 51/179 (28%), Positives = 83/179 (46%), Gaps = 3/179 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ P G++ L L+ ++K ++ HTTRS R E GR+YHF+S F A
Sbjct 18 FMVVAPSGAGKSTLVNALLAQDKA-IRLSISHTTRSPRPGEQNGREYHFISVDEFRAARD 76
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+F+E E N Y TS + + + G LL + Q + + IFI PPS
Sbjct 77 RGEFLEWAEVHGNYYATSRVWIEEQMAQGTDVLLEIDWQGAQQVHKRFSNAVEIFILPPS 136
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
L L K G++ +R ++ EM + D I+N D A ++L +++
Sbjct 137 LTALEERLKKRGQDEPNVIVRRLLAAGSEMSHASES--DYVIINEVFDDALKQLQNVVH 193
>sp|Q6AF82|KGUA_LEIXX Guanylate kinase OS=Leifsonia xyli subsp.
xyli (strain CTCB07) OX=281090 GN=gmk PE=3 SV=1
Length=254
Score = 74.7 bits (182), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 53/179 (30%), Positives = 87/179 (49%), Gaps = 4/179 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++L GP G+ + + + S V TTRS R EV G +Y+FV AF+ IA
Sbjct 67 VVLAGPTAVGKGTVSAYIRENYPEVLLS-VSATTRSPRPGEVDGVNYYFVDDAAFDRMIA 125
Query 542 AGKFIEHGEFEKNL-YGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
AG +EH YGT + + ++ G+ LL + Q + +R S + +IF+ PP
Sbjct 126 AGDLLEHATVHNAYRYGTPRAPIEKALDDGRSVLLEIDLQGARQVRASMPEARLIFLLPP 185
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
+ E L L G E+ R + +T ++E + FD +VN + A +E++ L+
Sbjct 186 TWEELVRRLTGRGTEDAAEQQRRL--ETAKVELAAQNEFDHRVVNHTVADAAREVVDLM 242
>sp|Q31DP7|KGUA_HYDCU Guanylate kinase OS=Hydrogenovibrio crunogenus
(strain DSM 25203 / XCL-2) OX=317025 GN=gmk PE=3 SV=1
Length=205
Score = 73.6 bits (179), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 51/173 (29%), Positives = 79/173 (46%), Gaps = 3/173 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I+ P G+ L +L K+ R ++ TTR +R E G +Y F+S AF+ +A
Sbjct 7 IISAPSGAGKTSLVSKLTEKDS-RIQVSISSTTRPKRPGEEDGVNYVFLSVDAFKQKVAE 65
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
F+EH + N YGTS V + K +L + Q + +R +FI PPS
Sbjct 66 NDFLEHAQVFDNYYGTSKSVVESKLAEDKDVILEIDWQGAQQVRKLIPDAVSVFILPPSL 125
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
+ L L G + + R + + EM+ N FD ++N+ D A EL
Sbjct 126 KELEKRLRGRGTDSEDVIERRMSDAVNEMKHFNE--FDYLVINNHFDTALSEL 176
>sp|Q479A8|KGUA_DECAR Guanylate kinase OS=Dechloromonas aromatica
(strain RCB) OX=159087 GN=gmk PE=3 SV=1
Length=202
Score = 73.2 bits (178), Expect = 2e-13, Method: Composition-based stats.
Identities = 53/173 (31%), Positives = 78/173 (45%), Gaps = 3/173 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
++ P G+ L + L+ +E S + +TTR R E GR+YHFV F A IA
Sbjct 7 VVAAPSGAGKTTLVRMLLEQESSVNLS-ISYTTRHPRPGEQNGREYHFVETPEFRAMIAR 65
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
+F+E E N YGTS + + +G+ LL + Q + +R + +FI PPS
Sbjct 66 QEFLEWAEVHGNFYGTSKKWIADQLAAGRDVLLEIDWQGAQQVRALFPQAIGVFILPPSM 125
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
E L L G + R + EM FD I+N L +A +L
Sbjct 126 EELTRRLTGRGTDSPDVIDRRLAAAQAEMRHVG--EFDYVIINDQLAQALDDL 176
>sp|Q66GE5|KGUA_YERPS Guanylate kinase OS=Yersinia pseudotuberculosis
serotype I (strain IP32953) OX=273123 GN=gmk PE=3 SV=1
Length=207
Score = 73.6 bits (179), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 60/184 (33%), Positives = 88/184 (48%), Gaps = 15/184 (8%)
Query 483 ILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ + D S + HTTR++R E G Y FVS + F I
Sbjct 8 IVSAPSGAGKSSLIQALLKTQPLYDTQVS-ISHTTRAKRPGENHGEHYFFVSEKEFCQMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
F+EH + +N YGTS ++ QV+ +G L + Q + +R IFI PP
Sbjct 67 DDDAFLEHAKVFENYYGTSRLAIEQVLATGVDVFLDIDWQGAQQIRAKMPTARSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQ---NNGHY--FDTAIVNSDLDKAYQEL 655
S+ L L G++ + E+I K MEQ HY +D IVN D + A +L
Sbjct 127 SKTELDRRLRGRGQDSE-----EVIAK--RMEQAVAEMAHYAEYDYLIVNDDFNLALSDL 179
Query 656 LRLI 659
+I
Sbjct 180 KTII 183
>sp|Q1CCZ3|KGUA_YERPN Guanylate kinase OS=Yersinia pestis bv.
Antiqua (strain Nepal516) OX=377628 GN=gmk PE=3 SV=1
Length=207
Score = 73.6 bits (179), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 60/184 (33%), Positives = 88/184 (48%), Gaps = 15/184 (8%)
Query 483 ILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ + D S + HTTR++R E G Y FVS + F I
Sbjct 8 IVSAPSGAGKSSLIQALLKTQPLYDTQVS-ISHTTRAKRPGENHGEHYFFVSEKEFCQMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
F+EH + +N YGTS ++ QV+ +G L + Q + +R IFI PP
Sbjct 67 DDDAFLEHAKVFENYYGTSRLAIEQVLATGVDVFLDIDWQGAQQIRAKMPTARSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQ---NNGHY--FDTAIVNSDLDKAYQEL 655
S+ L L G++ + E+I K MEQ HY +D IVN D + A +L
Sbjct 127 SKTELDRRLRGRGQDSE-----EVIAK--RMEQAVAEMAHYAEYDYLIVNDDFNLALSDL 179
Query 656 LRLI 659
+I
Sbjct 180 KTII 183
>sp|Q8ZJQ2|KGUA_YERPE Guanylate kinase OS=Yersinia pestis OX=632
GN=gmk PE=3 SV=1
Length=207
Score = 73.6 bits (179), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 60/184 (33%), Positives = 88/184 (48%), Gaps = 15/184 (8%)
Query 483 ILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ + D S + HTTR++R E G Y FVS + F I
Sbjct 8 IVSAPSGAGKSSLIQALLKTQPLYDTQVS-ISHTTRAKRPGENHGEHYFFVSEKEFCQMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
F+EH + +N YGTS ++ QV+ +G L + Q + +R IFI PP
Sbjct 67 DDDAFLEHAKVFENYYGTSRLAIEQVLATGVDVFLDIDWQGAQQIRAKMPTARSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQ---NNGHY--FDTAIVNSDLDKAYQEL 655
S+ L L G++ + E+I K MEQ HY +D IVN D + A +L
Sbjct 127 SKTELDRRLRGRGQDSE-----EVIAK--RMEQAVAEMAHYAEYDYLIVNDDFNLALSDL 179
Query 656 LRLI 659
+I
Sbjct 180 KTII 183
>sp|Q1C258|KGUA_YERPA Guanylate kinase OS=Yersinia pestis bv.
Antiqua (strain Antiqua) OX=360102 GN=gmk PE=3 SV=1
Length=207
Score = 73.6 bits (179), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 60/184 (33%), Positives = 88/184 (48%), Gaps = 15/184 (8%)
Query 483 ILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ + D S + HTTR++R E G Y FVS + F I
Sbjct 8 IVSAPSGAGKSSLIQALLKTQPLYDTQVS-ISHTTRAKRPGENHGEHYFFVSEKEFCQMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
F+EH + +N YGTS ++ QV+ +G L + Q + +R IFI PP
Sbjct 67 DDDAFLEHAKVFENYYGTSRLAIEQVLATGVDVFLDIDWQGAQQIRAKMPTARSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQ---NNGHY--FDTAIVNSDLDKAYQEL 655
S+ L L G++ + E+I K MEQ HY +D IVN D + A +L
Sbjct 127 SKTELDRRLRGRGQDSE-----EVIAK--RMEQAVAEMAHYAEYDYLIVNDDFNLALSDL 179
Query 656 LRLI 659
+I
Sbjct 180 KTII 183
>sp|Q819T6|KGUA_BACCR Guanylate kinase OS=Bacillus cereus (strain
ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305
/ NCIMB 9373 / NCTC 2599 / NRRL B-3711) OX=226900 GN=gmk PE=3
SV=1
Length=205
Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 47/138 (34%), Positives = 69/138 (50%), Gaps = 0/138 (0%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+L P G+ +R+ L + E RF ++ TTR R+ EV G DY F R+
Sbjct 3 SRRGLLIVLSRPSGVGKGTVRKELFSHEDTRFQYSISVTTRKPREGEVDGVDYFFKEREE 62
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I K +E EF N YGT ID V + + GK L + Q ++ + + I
Sbjct 63 FEEMIRNEKLLEWAEFVGNYYGTPIDYVEKTLQEGKDVFLEIEVQGAIQVKKAFPEGVFI 122
Query 596 FIAPPSQERLRALLAKEG 613
F+APPS L++ + G
Sbjct 123 FLAPPSLSELKSRIVGRG 140
>sp|Q2L090|KGUA_BORA1 Guanylate kinase OS=Bordetella avium (strain
197N) OX=360910 GN=gmk PE=3 SV=1
Length=210
Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 49/179 (27%), Positives = 87/179 (49%), Gaps = 3/179 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ P G++ L + L++++ S + TTR+ R E GRDYHFV+++AF A
Sbjct 9 FMVVAPSGAGKSSLVRALLDRDPSIVLS-ISSTTRAPRPGEQDGRDYHFVTKEAFLAQRE 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
A +E E N YGT + +G+ LL + Q + ++ + IFI PPS
Sbjct 68 ANNLLEWAEVHGNFYGTPRGRIDAATAAGQDVLLEIDWQGARQVKQRYPEAIGIFILPPS 127
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
E L+ L G++ + R ++ E+ + + I+N + A EL ++I+
Sbjct 128 IEALQERLKARGQDSEQVISRRLLAAGGEIA--HAPECEYVIINQEFSLALSELTQIIS 184
>sp|Q9PL09|KGUA_CHLMU Guanylate kinase OS=Chlamydia muridarum
(strain MoPn / Nigg) OX=243161 GN=gmk PE=3 SV=1
Length=205
Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 55/175 (31%), Positives = 78/175 (45%), Gaps = 13/175 (7%)
Query 486 GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKF 545
P G+ L L + F V TTRS R EV G DY F+S F+ + F
Sbjct 25 APAGAGKTTLVHMLQEEFPSAFEKTVSSTTRSPRPGEVHGVDYVFMSEDEFKDVLDKDGF 84
Query 546 IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERL 605
+E YGTS + + +++ GK C+ + Q TL+ ++ IFI PSQE L
Sbjct 85 LEWVFLFGTYYGTSKEGISRILQKGKHCIAVIDVQGALTLKK-QMQTVAIFIQAPSQEEL 143
Query 606 RALLAKEGKNPKPEELREIIEKTREMEQNN-----GHYFDTAIVNSDLDKAYQEL 655
L N + E + ++K +E +N FD +VN DL AYQ L
Sbjct 144 ERRL-----NTRDSE--KDLQKKERLEHSNVEIAAASQFDYVVVNDDLTTAYQVL 191
>sp|P9WKE9|KGUA_MYCTU Guanylate kinase OS=Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv) OX=83332 GN=gmk PE=1 SV=1
Length=208
Score = 73.2 bits (178), Expect = 2e-13, Method: Composition-based stats.
Identities = 58/195 (30%), Positives = 92/195 (47%), Gaps = 19/195 (10%)
Query 474 QPANRKRPIILIGPQNCGQNE----LRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYH 529
QPA R ++L GP G++ LR+R+ N +V TTR+ R EV G DYH
Sbjct 16 QPAAVGRVVVLSGPSAVGKSTVVRCLRERIPN-----LHFSVSATTRAPRPGEVDGVDYH 70
Query 530 FVSRQAFEADIAAGKFIEHGEFEKNLY--GTSIDSVRQVINSGKICLLSLRTQSLKTLRN 587
F+ F+ I G+ +E E L+ GT VR +G L+ + + ++
Sbjct 71 FIDPTRFQQLIDQGELLEWAEIHGGLHRSGTLAQPVRAAAATGVPVLIEVDLAGARAIKK 130
Query 588 SDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEK---TREMEQNNGHYFDTAIV 644
+ + +F+APPS + L+A L G E ++I++ T +E FD +V
Sbjct 131 TMPEAVTVFLAPPSWQDLQARLIGRGT-----ETADVIQRRLDTARIELAAQGDFDKVVV 185
Query 645 NSDLDKAYQELLRLI 659
N L+ A EL+ L+
Sbjct 186 NRRLESACAELVSLL 200
>sp|P9WKE8|KGUA_MYCTO Guanylate kinase OS=Mycobacterium tuberculosis
(strain CDC 1551 / Oshkosh) OX=83331 GN=gmk PE=3 SV=1
Length=208
Score = 73.2 bits (178), Expect = 2e-13, Method: Composition-based stats.
Identities = 58/195 (30%), Positives = 92/195 (47%), Gaps = 19/195 (10%)
Query 474 QPANRKRPIILIGPQNCGQNE----LRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYH 529
QPA R ++L GP G++ LR+R+ N +V TTR+ R EV G DYH
Sbjct 16 QPAAVGRVVVLSGPSAVGKSTVVRCLRERIPN-----LHFSVSATTRAPRPGEVDGVDYH 70
Query 530 FVSRQAFEADIAAGKFIEHGEFEKNLY--GTSIDSVRQVINSGKICLLSLRTQSLKTLRN 587
F+ F+ I G+ +E E L+ GT VR +G L+ + + ++
Sbjct 71 FIDPTRFQQLIDQGELLEWAEIHGGLHRSGTLAQPVRAAAATGVPVLIEVDLAGARAIKK 130
Query 588 SDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEK---TREMEQNNGHYFDTAIV 644
+ + +F+APPS + L+A L G E ++I++ T +E FD +V
Sbjct 131 TMPEAVTVFLAPPSWQDLQARLIGRGT-----ETADVIQRRLDTARIELAAQGDFDKVVV 185
Query 645 NSDLDKAYQELLRLI 659
N L+ A EL+ L+
Sbjct 186 NRRLESACAELVSLL 200
>sp|P0A5I5|KGUA_MYCBO Guanylate kinase OS=Mycobacterium bovis
(strain ATCC BAA-935 / AF2122/97) OX=233413 GN=gmk PE=3 SV=1
Length=208
Score = 73.2 bits (178), Expect = 2e-13, Method: Composition-based stats.
Identities = 58/195 (30%), Positives = 92/195 (47%), Gaps = 19/195 (10%)
Query 474 QPANRKRPIILIGPQNCGQNE----LRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYH 529
QPA R ++L GP G++ LR+R+ N +V TTR+ R EV G DYH
Sbjct 16 QPAAVGRVVVLSGPSAVGKSTVVRCLRERIPN-----LHFSVSATTRAPRPGEVDGVDYH 70
Query 530 FVSRQAFEADIAAGKFIEHGEFEKNLY--GTSIDSVRQVINSGKICLLSLRTQSLKTLRN 587
F+ F+ I G+ +E E L+ GT VR +G L+ + + ++
Sbjct 71 FIDPTRFQQLIDQGELLEWAEIHGGLHRSGTLAQPVRAAAATGVPVLIEVDLAGARAIKK 130
Query 588 SDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEK---TREMEQNNGHYFDTAIV 644
+ + +F+APPS + L+A L G E ++I++ T +E FD +V
Sbjct 131 TMPEAVTVFLAPPSWQDLQARLIGRGT-----ETADVIQRRLDTARIELAAQGDFDKVVV 185
Query 645 NSDLDKAYQELLRLI 659
N L+ A EL+ L+
Sbjct 186 NRRLESACAELVSLL 200
>sp|Q8G813|KGUA_BIFLO Guanylate kinase OS=Bifidobacterium longum
(strain NCC 2705) OX=206672 GN=gmk PE=3 SV=1
Length=196
Score = 72.4 bits (176), Expect = 3e-13, Method: Composition-based stats.
Identities = 59/190 (31%), Positives = 92/190 (48%), Gaps = 14/190 (7%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
R I+L GP G+ + +L + + S V TTR+ R EV G +Y F++ F A
Sbjct 9 RLIVLTGPTAVGKGTVEAKLRADHPEVWVS-VSATTRAPRPGEVDGVNYWFLTEDEFLAR 67
Query 540 IAAGKFIE----HGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS----DLK 591
AAG+F+E HG YGT + V + + +G +L + Q + ++ DL+
Sbjct 68 EAAGEFLETAVVHGMAH---YGTLLKPVEEHLAAGVPTILEIDLQGARRVKQRAAELDLE 124
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
+FIAPPS E L L G ++ R + +T ++E FD IVN +D+A
Sbjct 125 VVYVFIAPPSFEELERRLIGRGTETAEQQARRL--ETAKVELAAESEFDVTIVNETVDQA 182
Query 652 YQELLRLINK 661
+L +I K
Sbjct 183 AADLWSVIAK 192
>sp|Q6DB60|KGUA_PECAS Guanylate kinase OS=Pectobacterium atrosepticum
(strain SCRI 1043 / ATCC BAA-672) OX=218491 GN=gmk PE=3
SV=1
Length=207
Score = 72.4 bits (176), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 54/167 (32%), Positives = 79/167 (47%), Gaps = 9/167 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L Q L+ + D S + HTTR++R E G Y FV F+ I
Sbjct 8 IVSAPSGAGKSSLIQALLKTQPLYDTQVS-ISHTTRAKRPGENHGEHYFFVEADEFKRMI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
+F+EH E N YGTS ++ QV+ +G L + Q + +R + IFI PP
Sbjct 67 QDSEFLEHAEVFGNYYGTSRPAIEQVLATGVDVFLDIDWQGAQQIRAKMPQARSIFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVN 645
S+E L L G++ R + + EM HY +D IVN
Sbjct 127 SKEELARRLRGRGQDSDEVIARRMSQAVAEMT----HYGEYDYLIVN 169
>sp|Q82SQ3|KGUA_NITEU Guanylate kinase OS=Nitrosomonas europaea
(strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)
OX=228410 GN=gmk PE=3 SV=1
Length=201
Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 52/190 (27%), Positives = 90/190 (47%), Gaps = 5/190 (3%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++ P G+ + + L+ + + ++ +TTR R E G DY FV F+ A
Sbjct 5 FVISAPSGAGKTSVIRTLLQTDIN-LTLSISYTTRPPRRDEKNGHDYFFVDHATFKDMQA 63
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+F+E E NLYGTS + + + + + LL + Q + +R + IFI PPS
Sbjct 64 RGEFLESAEVHGNLYGTSRKWIEETMAAEQDVLLEIDCQGAQQIRTVYPQAASIFILPPS 123
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN- 660
E L+ L + G++ R + E+ N FD +VN +L+ A +++ ++
Sbjct 124 MEALKQRLEQRGQDENKVIERRLAAARSEISHVN--RFDYVVVNHELETAARDVASIVQA 181
Query 661 -KLDTEPQWV 669
+L T Q V
Sbjct 182 ERLKTIRQLV 191
>sp|Q4A6S7|KGUA_MYCS5 Guanylate kinase OS=Mycoplasmopsis synoviae
(strain 53) OX=262723 GN=gmk PE=3 SV=1
Length=198
Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 50/193 (26%), Positives = 89/193 (46%), Gaps = 13/193 (7%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+K +I GP G+ + Q + N ++ + + TTRS R E G Y+F+S++ F+
Sbjct 5 KKSIVIFTGPSGVGKGTVEQLVFNYDELNLSLSCSATTRSPRGGETNGIHYYFISKEEFK 64
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRT-------QSLKTLRNSDL 590
I KF+EH N YGT + +I K+ L + T Q ++ L+N
Sbjct 65 DRIKNKKFLEHSFHFDNYYGTLYSELDNIIARNKVPFLEIETNGAKIIAQKMQKLKNPPY 124
Query 591 KPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTRE--MEQNNGHYFDTAIVNSDL 648
IF++PPS + + G + ++ + K +E +E N F + N
Sbjct 125 NLITIFLSPPSITDIYKRIKNRG-TENAQTIKNRVNKAKEELLEAGN---FKYVVYNDRP 180
Query 649 DKAYQELLRLINK 661
++A QE+ +++K
Sbjct 181 ERAAQEIREILHK 193
>sp|Q8K9C7|KGUA_BUCAP Guanylate kinase OS=Buchnera aphidicola
subsp. Schizaphis graminum (strain Sg) OX=198804 GN=gmk PE=3
SV=1
Length=207
Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 52/184 (28%), Positives = 87/184 (47%), Gaps = 13/184 (7%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFAS----AVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
I+ P G++ L + L+ K +F ++ HTTR R E G+ Y+F+S++ F
Sbjct 7 FIISAPSGTGKSSLIEGLL---KTKFLYNIQVSISHTTRVMRPGESHGKHYYFISKKEFR 63
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I F+E+ + N YGTS S+ +++ SG L + Q +R IF+
Sbjct 64 IMIKQESFLEYAKVFNNYYGTSRQSIEKMLLSGIDVFLDIDWQGANQIRYKMPNSKSIFL 123
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQEL 655
PPS++ L L + G++ + + + EM HY +D I+N D KA +L
Sbjct 124 LPPSKDELYKRLRERGQDSDTVISKRMEKAVDEM----NHYSEYDYLIINDDFQKAINDL 179
Query 656 LRLI 659
+I
Sbjct 180 RTII 183
>sp|Q2S6J5|KGUA_SALRD Guanylate kinase OS=Salinibacter ruber (strain
DSM 13855 / M31) OX=309807 GN=gmk PE=3 SV=1
Length=188
Score = 71.6 bits (174), Expect = 4e-13, Method: Composition-based stats.
Identities = 55/182 (30%), Positives = 84/182 (46%), Gaps = 4/182 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++L P G+ + R++ D +V TTR+ R E G DYHF+S + F A I
Sbjct 7 VVLTAPSGAGKTTIAHRVLEAMPD-MQFSVSATTRAARPDETDGVDYHFLSPEEFRARID 65
Query 542 AGKFIEHGE-FEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
AG +E+ E + YGT V G + L +L R I+F+APP
Sbjct 66 AGDLLEYEEVYPDQFYGTLRSEVEDRAEDGPVLLDIDVKGALNVKRIFGDDALILFVAPP 125
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
S + L+ L G + E L++ +++ E E + D +VN DLD A +E L I
Sbjct 126 SLDELQRRLEGRGTEDR-ESLQDRLDRV-EQEMDRADDCDAVVVNDDLDPAVEETLTRIR 183
Query 661 KL 662
+
Sbjct 184 QF 185
>sp|Q8UGD7|KGUA_AGRFC Guanylate kinase OS=Agrobacterium fabrum
(strain C58 / ATCC 33970) OX=176299 GN=gmk PE=3 SV=1
Length=220
Score = 72.4 bits (176), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 92/183 (50%), Gaps = 12/183 (7%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A R +++ P G++ + + L+ K+K+ + +V TTR RR E+ G YHF+S++
Sbjct 12 ARRGLMLVISSPSGAGKSTIARNLLEKDKN-ISLSVSVTTRPRRQSEIEGIHYHFISKRD 70
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI- 594
FE + +E E N YGT + V + +G+ L + Q + L++ +
Sbjct 71 FERMRDGDELLEWAEVHGNFYGTPREPVEAAMAAGRDMLFDIDWQGAEQLQDKMKADVVS 130
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREM----EQNNGHYFDTAIVNSDLDK 650
IFI PP+ L++ L + + E+ E+I KTR + E + +D I+N DL
Sbjct 131 IFILPPTMTELQSRLHR-----RAEDSEEVI-KTRLLNSRAEIEHWRDYDYVILNDDLQA 184
Query 651 AYQ 653
A++
Sbjct 185 AFE 187
>sp|Q13V49|KGUA_PARXL Guanylate kinase OS=Paraburkholderia xenovorans
(strain LB400) OX=266265 GN=gmk PE=3 SV=1
Length=225
Score = 72.4 bits (176), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 50/178 (28%), Positives = 82/178 (46%), Gaps = 3/178 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ P G++ L L+ + D ++ +TTR R +E+ G YHF + F
Sbjct 23 FMVVAPSGAGKSTLVNALLAGD-DAIRLSISYTTRPPRPKELDGEHYHFTTVDDFMKRHD 81
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
AG+F+E E N YGTS + + SG LL + Q + ++ IFI PPS
Sbjct 82 AGEFLESAEVHGNYYGTSRVWIEDQMKSGHDVLLEIDWQGAQQVKKQFHNAVEIFILPPS 141
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
E L L K G++ R ++ EM + + ++N + D+A EL L+
Sbjct 142 LEALEERLKKRGQDEPNVITRRLLAAGSEMA--HAAEAEYVVINENFDRALSELQCLV 197
>sp|P65218|KGUA_BRUSU Guanylate kinase OS=Brucella suis biovar
1 (strain 1330) OX=204722 GN=gmk PE=3 SV=1
Length=220
Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 51/195 (26%), Positives = 90/195 (46%), Gaps = 9/195 (5%)
Query 470 SLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYH 529
S+ + A R +++ P G++ + + L+ K + + ++ TTR RR E+ G YH
Sbjct 5 SVENGVARRGLMVVISSPSGAGKSTIARLLLEDPKMKLSLSISVTTRQRRPSEIDGVHYH 64
Query 530 FVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD 589
F++ + FE + IE E N YGT ++ + G+ L + Q L+
Sbjct 65 FITIREFERLRDNDELIEWAEVHGNFYGTLRETAEIALADGQDMLFDIDWQGADQLQAKM 124
Query 590 LKPYI-IFIAPPSQERLRALLAKEGKNPKPEELREIIE---KTREMEQNNGHYFDTAIVN 645
+ IFI PP+ L+ L N + E+ E+IE + E +D ++N
Sbjct 125 PADVVSIFILPPTMRELQQRL-----NRRAEDTAEVIETRLQNARFEIQKWVKYDYIVIN 179
Query 646 SDLDKAYQELLRLIN 660
DLD++Y + +IN
Sbjct 180 EDLDRSYAAIKSIIN 194
>sp|P65217|KGUA_BRUME Guanylate kinase OS=Brucella melitensis
biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) OX=224914 GN=gmk
PE=3 SV=1
Length=220
Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 51/195 (26%), Positives = 90/195 (46%), Gaps = 9/195 (5%)
Query 470 SLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYH 529
S+ + A R +++ P G++ + + L+ K + + ++ TTR RR E+ G YH
Sbjct 5 SVENGVARRGLMVVISSPSGAGKSTIARLLLEDPKMKLSLSISVTTRQRRPSEIDGVHYH 64
Query 530 FVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD 589
F++ + FE + IE E N YGT ++ + G+ L + Q L+
Sbjct 65 FITIREFERLRDNDELIEWAEVHGNFYGTLRETAEIALADGQDMLFDIDWQGADQLQAKM 124
Query 590 LKPYI-IFIAPPSQERLRALLAKEGKNPKPEELREIIE---KTREMEQNNGHYFDTAIVN 645
+ IFI PP+ L+ L N + E+ E+IE + E +D ++N
Sbjct 125 PADVVSIFILPPTMRELQQRL-----NRRAEDTAEVIETRLQNARFEIQKWVKYDYIVIN 179
Query 646 SDLDKAYQELLRLIN 660
DLD++Y + +IN
Sbjct 180 EDLDRSYAAIKSIIN 194
>sp|Q57EQ3|KGUA_BRUAB Guanylate kinase OS=Brucella abortus biovar
1 (strain 9-941) OX=262698 GN=gmk PE=3 SV=1
Length=220
Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 51/195 (26%), Positives = 90/195 (46%), Gaps = 9/195 (5%)
Query 470 SLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYH 529
S+ + A R +++ P G++ + + L+ K + + ++ TTR RR E+ G YH
Sbjct 5 SVENGVARRGLMVVISSPSGAGKSTIARLLLEDPKMKLSLSISVTTRQRRPSEIDGVHYH 64
Query 530 FVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD 589
F++ + FE + IE E N YGT ++ + G+ L + Q L+
Sbjct 65 FITIREFERLRDNDELIEWAEVHGNFYGTLRETAEIALADGQDMLFDIDWQGADQLQAKM 124
Query 590 LKPYI-IFIAPPSQERLRALLAKEGKNPKPEELREIIE---KTREMEQNNGHYFDTAIVN 645
+ IFI PP+ L+ L N + E+ E+IE + E +D ++N
Sbjct 125 PADVVSIFILPPTMRELQQRL-----NRRAEDTAEVIETRLQNARFEIQKWVKYDYIVIN 179
Query 646 SDLDKAYQELLRLIN 660
DLD++Y + +IN
Sbjct 180 EDLDRSYAAIKSIIN 194
>sp|Q2YMJ2|KGUA_BRUA2 Guanylate kinase OS=Brucella abortus (strain
2308) OX=359391 GN=gmk PE=3 SV=1
Length=220
Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 51/195 (26%), Positives = 90/195 (46%), Gaps = 9/195 (5%)
Query 470 SLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYH 529
S+ + A R +++ P G++ + + L+ K + + ++ TTR RR E+ G YH
Sbjct 5 SVENGVARRGLMVVISSPSGAGKSTIARLLLEDPKMKLSLSISVTTRQRRPSEIDGVHYH 64
Query 530 FVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD 589
F++ + FE + IE E N YGT ++ + G+ L + Q L+
Sbjct 65 FITIREFERLRDNDELIEWAEVHGNFYGTLRETAEIALADGQDMLFDIDWQGADQLQAKM 124
Query 590 LKPYI-IFIAPPSQERLRALLAKEGKNPKPEELREIIE---KTREMEQNNGHYFDTAIVN 645
+ IFI PP+ L+ L N + E+ E+IE + E +D ++N
Sbjct 125 PADVVSIFILPPTMRELQQRL-----NRRAEDTAEVIETRLQNARFEIQKWVKYDYIVIN 179
Query 646 SDLDKAYQELLRLIN 660
DLD++Y + +IN
Sbjct 180 EDLDRSYAAIKSIIN 194
>sp|P0C0M8|KGUA_STAEP Guanylate kinase (Fragment) OS=Staphylococcus
epidermidis OX=1282 GN=gmk PE=3 SV=1
Length=130
Score = 68.9 bits (167), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 34/107 (32%), Positives = 55/107 (51%), Gaps = 0/107 (0%)
Query 507 FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQV 566
+ ++ TTR R+ E+ G DY F +++ FEA I +FIE+ ++ N YGT + V+
Sbjct 10 YKYSISMTTRHMREGEIDGVDYFFKTKEEFEALIKDDQFIEYAQYVGNYYGTPVQYVKDT 69
Query 567 INSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEG 613
+ G L + + K +R IF+APPS + L+ L G
Sbjct 70 MEEGHDVFLEIEVEGAKQVRKKFPDALFIFLAPPSLDDLKERLVGRG 116
>sp|Q46YE8|KGUA_CUPPJ Guanylate kinase OS=Cupriavidus pinatubonensis
(strain JMP 134 / LMG 1197) OX=264198 GN=gmk PE=3 SV=1
Length=216
Score = 71.2 bits (173), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 49/178 (28%), Positives = 81/178 (46%), Gaps = 3/178 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ P G++ L L+ ++ ++ HTTR+ R E GR+YHF + +F A
Sbjct 18 FMVVAPSGAGKSTLVNALLAQDAA-IRLSISHTTRAPRPGEQDGREYHFCTVDSFRAARD 76
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+F+E E N Y TS + + + G LL + Q + + IFI PPS
Sbjct 77 RGEFLEWAEVHGNYYATSRVWIEEQMAQGNDVLLEIDWQGAQQVHQRFSNAVEIFILPPS 136
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
L L K G++ +R ++ EM + D I+N D A +EL ++
Sbjct 137 LTALEDRLKKRGQDEPNVIVRRLLAAGSEMSHASES--DYVIINEVFDNALEELRNVV 192
>sp|Q5L5M1|KGUA_CHLAB Guanylate kinase OS=Chlamydia abortus (strain
DSM 27085 / S26/3) OX=218497 GN=gmk PE=3 SV=1
Length=204
Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 50/173 (29%), Positives = 82/173 (47%), Gaps = 9/173 (5%)
Query 486 GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKF 545
P G+ L + L + D F + TTR+ R +E+ G DY FVS++ F+ + F
Sbjct 25 APAGAGKTTLVRMLAREFPDSFQKTLSLTTRAPRPEEIPGVDYQFVSQEEFQRRLDNEDF 84
Query 546 IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERL 605
+E YGTS + ++ SG+ + + + L+ S + IFI+ PSQE L
Sbjct 85 LEWVALFGEYYGTSRLGIDEIWKSGRHAVAVIDVEGALVLQ-SKIPTVAIFISAPSQEEL 143
Query 606 RALLAKEGK---NPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
L + G + E L+ + +EQ F+ I+N DL+K+Y+ L
Sbjct 144 ERRLKQRGSEQDTQRQERLQHSL-----IEQAAADKFEYVIINDDLEKSYEVL 191
>sp|P60550|KGUA_CORDI Guanylate kinase OS=Corynebacterium diphtheriae
(strain ATCC 700971 / NCTC 13129 / Biotype gravis) OX=257309
GN=gmk PE=3 SV=1
Length=191
Score = 70.5 bits (171), Expect = 1e-12, Method: Composition-based stats.
Identities = 53/184 (29%), Positives = 92/184 (50%), Gaps = 9/184 (5%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
R ++L GP G++ + RL + +D + S V TTR+ R E G DY FVS + F++
Sbjct 9 RLVVLAGPSAVGKSTVVHRLREEIEDLYFS-VSMTTRAPRPGERDGVDYFFVSPEEFQSK 67
Query 540 IAAGKFIE----HGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
I AG+ +E HG +++ GT V + +G+ L+ + + + + + +
Sbjct 68 IDAGEMLEWADIHGGLQRS--GTPAGPVEAALLAGRPVLVEVDLVGARNVASLKPESETV 125
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+APPS E L L G P+ R + +T + E H F +VN D++KA ++
Sbjct 126 FLAPPSWEVLVERLTGRGTEPEDVITRRL--ETAKNELTAQHEFKHVVVNEDVEKAVSDI 183
Query 656 LRLI 659
++
Sbjct 184 KEIL 187
>sp|Q135N9|KGUA_RHOPS Guanylate kinase OS=Rhodopseudomonas palustris
(strain BisB5) OX=316057 GN=gmk PE=3 SV=1
Length=219
Score = 70.9 bits (172), Expect = 2e-12, Method: Composition-based stats.
Identities = 51/174 (29%), Positives = 85/174 (49%), Gaps = 4/174 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
+L P G+ L R++ E +V TTR RR EV GRDY+FV R F+A + A
Sbjct 19 VLSSPSGAGKTTL-SRMLVDEAPGLTMSVSATTRPRRPGEVDGRDYYFVDRPKFDAMVEA 77
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-IFIAPPS 601
+F+E N YGT V + +G+ L + Q + LR+ + +FI PPS
Sbjct 78 DEFLEWAHVFDNCYGTPRAPVEAALAAGRDVLFDIDWQGTQQLRSRASNDVVSVFILPPS 137
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
+ L L ++ E +R ++K + E ++ +D +VN ++ A++ +
Sbjct 138 VQDLEHRLHTRAQDSD-EVIRGRMKKAGD-EMSHFDAYDYIVVNDNIGVAFESV 189
>sp|Q6LVP5|KGUA_PHOPR Guanylate kinase OS=Photobacterium profundum
(strain SS9) OX=298386 GN=gmk PE=3 SV=1
Length=208
Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 55/179 (31%), Positives = 78/179 (44%), Gaps = 5/179 (3%)
Query 483 ILIGPQNCGQNELRQRLM--NKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+ P G++ L L+ N D S V HTTR R E G Y+F+S + F
Sbjct 8 IVSAPSGAGKSSLINALLETNPTYDMKVS-VSHTTRGMRPGEENGVHYNFISVEEFTELT 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
F+EH E N YGTS + +N G L + Q + +R +FI PP
Sbjct 67 EQESFLEHAEVFGNYYGTSRPWIEDQLNKGIDVFLDIDWQGARQIRIQMPAAKSLFILPP 126
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
S+E L L G++ + R + E E+ N +D IVN D D A + +I
Sbjct 127 SKEELERRLNARGQDSETIIARRMQEARSEISHYNE--YDYVIVNDDFDAALMDFKAII 183
>sp|Q4JVH4|KGUA_CORJK Guanylate kinase OS=Corynebacterium jeikeium
(strain K411) OX=306537 GN=gmk PE=3 SV=1
Length=188
Score = 69.7 bits (169), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 48/157 (31%), Positives = 77/157 (49%), Gaps = 8/157 (5%)
Query 473 HQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVS 532
Q N R ++L GP G++ + +RL D F S V TTR R EV G DY +V+
Sbjct 2 SQDLNSGRIVVLAGPSAVGKSTVVRRLRTDVPDLFFS-VSMTTRDPRPGEVDGEDYIYVT 60
Query 533 RQAFEADIAAGKFIEHGEFEKN--LYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL 590
R+ FE +IAA K +E E L GT + + + + + L+ + + + ++
Sbjct 61 REQFEQNIAADKMLEWAEIHGGLQLSGTPREPIEKALAESRPVLVEVDLEGARNVKKMLP 120
Query 591 KPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEK 627
+ +F+APPS E L L G E +++IE+
Sbjct 121 QVQTVFLAPPSWEELVDRLTGRGT-----ETQDVIER 152
>sp|Q2IL45|KGUA_ANADE Guanylate kinase OS=Anaeromyxobacter dehalogenans
(strain 2CP-C) OX=290397 GN=gmk PE=3 SV=1
Length=226
Score = 70.5 bits (171), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 52/194 (27%), Positives = 87/194 (45%), Gaps = 9/194 (5%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++L P G+ L RL D S + TTR+ R E G DYHFV+ + F +A
Sbjct 16 LVLSAPSGAGKTTLAHRLREASPDAVFS-ISATTRAPRGAEREGVDYHFVTAERFTELVA 74
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS-DLKPYIIFIAPP 600
G F E E YGT +V + + +GK+ L + Q ++ + + + + PP
Sbjct 75 QGAFAEWAEVHGQRYGTLRATVDEALAAGKLALFDIDVQGGAQIKAAWPQQAATVLVLPP 134
Query 601 SQERLRALLAKEGKNPKPEEL--REIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
+ L L G++ +E R ++ E+ + G Y D +VN L+ A +L +
Sbjct 135 DEAELERRL--RGRDTDSDETIRRRLVAARAEVARGLGSY-DYVVVNDVLEGALAQLQAI 191
Query 659 IN--KLDTEPQWVP 670
+ +L +W P
Sbjct 192 VRHERLRHAGRWDP 205
>sp|Q8TDM6|DLG5_HUMAN Disks large homolog 5 OS=Homo sapiens OX=9606
GN=DLG5 PE=1 SV=4
Length=1919
Score = 74.3 bits (181), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 96/450 (21%), Positives = 194/450 (43%), Gaps = 61/450 (14%)
Query 255 KIVRIEKARDIPLGA-TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
++V I+K++ + LG + V ++ + A+ L GD +LE +++R K
Sbjct 1501 RVVFIKKSQ-LELGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKT 1559
Query 314 VNEVF-DLLSDMHGT-LTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGL 371
V EV+ ++L G L P + K +++A +D + E L
Sbjct 1560 VEEVYVEMLKPRDGVRLKVQYRPEEFTKAKGLPGDSFYIRALYDR-------LADVEQEL 1612
Query 372 SFQKGDILHV---ISQEDPNWWQAYREGDEDNQPLA-GLVPGKSFQQQREAMKQTIEEDK 427
SF+K DIL+V + Q W A+ + DE+ Q + G +P K Q + + ++ E K
Sbjct 1613 SFKKDDILYVDDTLPQGTFGSWMAW-QLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVK 1671
Query 428 EPEKSGKLWCAK------KNKKKRKKVLYNANKN----DDYDNEEILTYEE-MSLYHQPA 476
+ + K A + K K K+ K+ D + ++ I +E+ +SL +Q
Sbjct 1672 DDNSATKTLSAAARRSFFRRKHKHKRSGSKDGKDLLALDAFSSDSIPLFEDSVSLAYQRV 1731
Query 477 NRK-----RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFV 531
+ RP++++GP + +++ L+N+ +F ++
Sbjct 1732 QKVDCTALRPVLILGPL---LDVVKEMLVNEAPGKFCRCPLEVMKA-------------- 1774
Query 532 SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK 591
S+QA E + F+++ + T++ S++++ + CLL + +++ L + +
Sbjct 1775 SQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNRHCLLDIAPHAIERLHHMHIY 1834
Query 592 PYIIFIAPPSQERLRALLAKEGKNP-------KPEELREIIEKTREMEQNNGHYFDTAIV 644
P +IFI S + + KE ++P +E E +++EQ YF I
Sbjct 1835 PIVIFIHYKSAKHI-----KEQRDPIYLRDKVTQRHSKEQFEAAQKLEQEYSRYFTGVIQ 1889
Query 645 NSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
L ++L ++N+ + W+P+ L
Sbjct 1890 GGALSSICTQILAMVNQEQNKVLWIPACPL 1919
Score = 43.1 bits (100), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 26/84 (31%), Positives = 40/84 (48%), Gaps = 3/84 (4%)
Query 250 GGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
GG+ V + I + G ++ N V + ++ G A K G L GD ++ INGI +
Sbjct 713 GGKVVTPLHINLSGQKDSGISLEN---GVYAAAVLPGSPAAKEGSLAVGDRIVAINGIAL 769
Query 310 RGKDVNEVFDLLSDMHGTLTFVLI 333
K +NE LL +LT L+
Sbjct 770 DNKSLNECESLLRSCQDSLTLSLL 793
Score = 38.1 bits (87), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 22/76 (29%), Positives = 42/76 (55%), Gaps = 3/76 (4%)
Query 257 VRIEKARDIPLG-ATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVN 315
V+++K + PLG + V E + +S++ G A ++GL + GD++LE NGI +R
Sbjct 1351 VKVQKGSE-PLGISIVSGEKGGIYVSKVTVGSIAHQAGLEY-GDQLLEFNGINLRSATEQ 1408
Query 316 EVFDLLSDMHGTLTFV 331
+ ++ T+T +
Sbjct 1409 QARLIIGQQCDTITIL 1424
>sp|Q1BY73|KGUA_BURO1 Guanylate kinase OS=Burkholderia orbicola
(strain AU 1054) OX=331271 GN=gmk PE=3 SV=1
Length=227
Score = 70.1 bits (170), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 83/174 (48%), Gaps = 3/174 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ P G++ L L++K+ D ++ +TTR R E G+ YHF + + F A A
Sbjct 24 FMVVAPSGAGKSTLVNALLSKDSD-ICLSISYTTRKPRPGEQDGQHYHFTTVEDFRARHA 82
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
A +F+E E N YGTS + + + +G LL + Q ++ IFI PPS
Sbjct 83 AHEFLESAEVHGNYYGTSRVWIEEQMRNGHDVLLEIDWQGALQVKKQFRNAVGIFILPPS 142
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
+ L L K G++ R ++ E+ + + ++N + ++A EL
Sbjct 143 LDALEERLKKRGQDEPNVITRRLLAAGSEIAHASEAEY--VVINENFERALAEL 194
>sp|Q7UP92|KGUA_RHOBA Guanylate kinase OS=Rhodopirellula baltica
(strain DSM 10527 / NCIMB 13988 / SH1) OX=243090 GN=gmk PE=3
SV=1
Length=209
Score = 69.7 bits (169), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 53/197 (27%), Positives = 93/197 (47%), Gaps = 6/197 (3%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ A+ R +I+ GP G++ + ++LM + +V TTR R E+ G+DY F+S
Sbjct 11 ETAHPGRLVIISGPSGAGKSTVVKQLMKRCDVPLQLSVSATTREPRPGEIHGQDYFFLSH 70
Query 534 QAFEADIAAGKFIEHGEFEK--NLYGTSIDSVRQVINSGKICLLSLRTQ-SLKTLRNSDL 590
+ FE F+E + YGT D V +N+GK +L + Q ++ L +
Sbjct 71 EEFERRRKLNDFVECKQVFSMGQWYGTLKDQVATGLNAGKWVILEIDVQGAMAVLDDPHY 130
Query 591 KPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDK 650
+P IF+ P S E L L G + + EM+ + + ++ I+N +D
Sbjct 131 RPVTIFVHPGSMEELERRLRNRGTESESSLTARLETAAAEMQCLSRYQYE--IINESVDN 188
Query 651 AYQELLR-LINKLDTEP 666
A E+ + L+++ T P
Sbjct 189 AVTEICQILLDQRKTTP 205
>sp|Q1RK99|KGUA_RICBR Guanylate kinase OS=Rickettsia bellii (strain
RML369-C) OX=336407 GN=gmk PE=3 SV=1
Length=191
Score = 68.9 bits (167), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 47/183 (26%), Positives = 87/183 (48%), Gaps = 3/183 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N+ IIL P G++ L + L+ + + ++ TTR R E G +Y+F ++ F
Sbjct 4 NKGLIIILSSPSGAGKSSLAKALLEIDHN-LRLSISATTRKPRPNEQDGVNYYFKTKVEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
E + +F+EH + N YGT V ++N G L + Q ++++ + + IF
Sbjct 63 EKLVKQNQFLEHAKIYDNYYGTPKKHVENLLNQGLDVLFDIDWQGARSIKQNAVNAVSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PP+ E L L + EE ++ + + E ++ + +D I N D + Q++
Sbjct 123 ILPPNLEVLEQRL--RNRAADNEEAIQLRMASAQAEISHSNEYDHIITNDDFNDTIQQIH 180
Query 657 RLI 659
+I
Sbjct 181 TII 183
>sp|Q6F1S1|KGUA_MESFL Guanylate kinase OS=Mesoplasma florum (strain
ATCC 33453 / NBRC 100688 / NCTC 11704 / L1) OX=265311
GN=gmk PE=3 SV=1
Length=297
Score = 71.2 bits (173), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 41/132 (31%), Positives = 67/132 (51%), Gaps = 2/132 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N+ + II+ GP G+ + L+ + + +V TTR+ R+ EV G +Y FVS++ F
Sbjct 3 NKGKVIIISGPSGVGKGSVNGELLTNKDLKLEYSVSMTTRAPREGEVNGVNYFFVSKEEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQ-SLKTLRNSDLKPYII 595
I + IE+ F N YGT V + +N GK +L + + + LRN + I
Sbjct 63 ANAIVNNELIEYANFVGNSYGTPRKYVEEKLNEGKNVILEIEVDGATQVLRNEE-NVLSI 121
Query 596 FIAPPSQERLRA 607
F+ PP+ L +
Sbjct 122 FLMPPTLNELES 133
>sp|P47353|KGUA_MYCGE Guanylate kinase OS=Mycoplasma genitalium
(strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37) OX=243273
GN=gmk PE=3 SV=2
Length=240
Score = 69.7 bits (169), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 51/182 (28%), Positives = 81/182 (45%), Gaps = 7/182 (4%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N+ R ++ GP G++ L + L++ K++ ++ TTR +R E G DY F + F
Sbjct 54 NQGRIFVITGPSGVGKSTLVKALLDHFKEQLFYSISATTRKKRISEKEGIDYFFKDKDEF 113
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY--- 593
E I FIE + + YGT Q I SG +L + Q L+ P+
Sbjct 114 ENLIKQDAFIEWACYNNHYYGTLKSQAEQAIKSGINLMLEIEYQG--ALQVKSKYPHNVV 171
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
+IFI PPS + L L K + + + + E +Q + F + N + DK
Sbjct 172 LIFIKPPSMQELLKRLKKRNDEDETTIKKRLEQAKIEFQQIDN--FKYVVTNKEFDKTLN 229
Query 654 EL 655
EL
Sbjct 230 EL 231
>sp|Q8EVJ9|KGUA_MALP2 Guanylate kinase OS=Malacoplasma penetrans
(strain HF-2) OX=272633 GN=gmk PE=3 SV=1
Length=196
Score = 68.9 bits (167), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 49/172 (28%), Positives = 86/172 (50%), Gaps = 4/172 (2%)
Query 486 GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKF 545
GP G+ + +++N ++ TTR R+ E G DY FVS + F + I G+
Sbjct 15 GPSGVGKKTIIDQVINNVDLNLTYSISMTTRLPREHEKNGVDYFFVSEEEFNSAIEKGEL 74
Query 546 IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS-DLKPYI-IFIAPPSQE 603
+E EF N YGT I ++ ++I K +L + Q +++ + + YI IF+ PPS
Sbjct 75 LEWAEFANNKYGTPIKNLYKLIGENKNVILEIEVQGATKVKDILNREDYISIFLIPPSIR 134
Query 604 RLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
L+ L K E++++ I++ + +E + +D I+N D A +L
Sbjct 135 ELKRRLKIRDTETK-EKIKQRIKRAK-VELKLQNEYDFIILNDDAKNAADKL 184
>sp|Q8FT45|KGUA_COREF Guanylate kinase OS=Corynebacterium efficiens
(strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC
100395) OX=196164 GN=gmk PE=3 SV=1
Length=190
Score = 68.6 bits (166), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 55/180 (31%), Positives = 85/180 (47%), Gaps = 9/180 (5%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
R +IL GP G++ + RL + + + S V TTR R EV GRDY +V+ Q F+
Sbjct 9 RLVILAGPSAVGKSTVVDRLRSDVPNLYFS-VSMTTRDPRPGEVDGRDYFYVTAQEFQEK 67
Query 540 IAAGKFIE----HGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
I G+ +E HG +++ GT + VRQ G+ L+ + + + + I
Sbjct 68 IDRGEMLEWADIHGGLQRS--GTPAEPVRQAREEGRPVLVEVDLVGARNIARLIPEAETI 125
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+APPS E L L G + + + +E RE E F I+N D+D A +
Sbjct 126 FLAPPSWEVLVERLTGRGTESQ-DVINRRLETARE-ELAAQSEFKHVIINDDVDTAVSAI 183
>sp|Q1D3A6|KGUA_MYXXD Guanylate kinase OS=Myxococcus xanthus (strain
DK1622) OX=246197 GN=gmk PE=3 SV=1
Length=209
Score = 68.6 bits (166), Expect = 7e-12, Method: Composition-based stats.
Identities = 45/174 (26%), Positives = 76/174 (44%), Gaps = 2/174 (1%)
Query 486 GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKF 545
P G+ L RL+ + D S + TTR R +E G DY+FV F++ I G+F
Sbjct 17 APSGAGKTTLAHRLLKETPDAVFS-ISVTTRRPRGKEREGVDYNFVDVATFQSKIERGEF 75
Query 546 IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERL 605
+E E + YG+ V + + + Q + ++ IF+ PPS E L
Sbjct 76 VEWAEVYGHFYGSPQSVVDEARARKSAAIFDIDVQGGQAIKRKHPDAVTIFVLPPSMEEL 135
Query 606 RALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
L + R ++ E+E+ Y D +VN D ++A+ +L ++
Sbjct 136 ERRLRDRQTDSDETIRRRMLAARSEIERGIASY-DYVVVNDDFERAFSDLRSVV 188
>sp|O95049|ZO3_HUMAN Tight junction protein ZO-3 OS=Homo sapiens
OX=9606 GN=TJP3 PE=1 SV=3
Length=919
Score = 72.0 bits (175), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 99/448 (22%), Positives = 175/448 (39%), Gaps = 90/448 (20%)
Query 254 VKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
++VR K + I L N++ + +S + G A+ G+ EGD++L++N + +
Sbjct 381 TRVVRFLKGKSIGLRLAGGNDV-GIFVSGVQAGSPADGQGI-QEGDQILQVNDVPFQNLT 438
Query 314 VNEVFDLLSDMHGT--LTFVLIPSQQIKPPPAKETV---IHVKAHFDYDPSDDPYVPCRE 368
E L + + V Q I + V +++ HF+ +PS P
Sbjct 439 REEAVQFLLGLPPGEEMELVTQRKQDIFWKMVQSRVGDSFYIRTHFELEPSP----PS-- 492
Query 369 LGLSFQKGDILHVISQEDP---------NWWQAYREGDEDNQPLAGLVPGKSFQQQ---R 416
GL F +GD+ HV+ P W A R G + + G++P +S +Q
Sbjct 493 -GLGFTRGDVFHVLDTLHPGPGQSHARGGHWLAVRMGRDLREQERGIIPNQSRAEQLASL 551
Query 417 EAMKQTI----EEDKEPEKSGKLW-------CAKKNKKKRKKVLYNANKNDDYDNEEILT 465
EA ++ + + W AKK ++ ++ L + Y E +
Sbjct 552 EAAQRAVGVGPGSSAGSNARAEFWRLRGLRRGAKKTTQRSREDLSALTRQGRYPPYERVV 611
Query 466 YEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAG 525
E S KRP++++GP + Q+L + D+F A T SR D
Sbjct 612 LREASF-------KRPVVILGPV---ADIAMQKLTAEMPDQFEIA---ETVSRTD----- 653
Query 526 RDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTL 585
+ K I+ +D+VR + K LL + +++ L
Sbjct 654 ---------------SPSKIIK------------LDTVRVIAEKDKHALLDVTPSAIERL 686
Query 586 RNSDLKPYIIFIAPPSQERLRAL---LAKEGKNPKPEELREIIEKTREMEQNNGHYFDTA 642
P ++F P S+ L+AL LA + R + + +++ +++ H F
Sbjct 687 NYVQYYPIVVFFIPESRPALKALRQWLAPASRR----STRRLYAQAQKLRKHSSHLFTAT 742
Query 643 I-VNSDLDKAYQELLRLINKLDTEPQWV 669
I +N D YQEL +I + T P W
Sbjct 743 IPLNGTSDTWYQELKAIIREQQTRPIWT 770
Score = 33.9 bits (76), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 16/56 (29%), Positives = 29/56 (52%), Gaps = 0/56 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
+ I I G A + L EGD +L+ING+ + +N+ L+ G L+ +++
Sbjct 214 IFIKHITDSGLAARHRGLQEGDLILQINGVSSQNLSLNDTRRLIEKSEGKLSLLVL 269
>sp|Q5NQE8|KGUA_ZYMMO Guanylate kinase OS=Zymomonas mobilis subsp.
mobilis (strain ATCC 31821 / ZM4 / CP4) OX=264203 GN=gmk
PE=3 SV=1
Length=216
Score = 68.6 bits (166), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 47/181 (26%), Positives = 84/181 (46%), Gaps = 4/181 (2%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A R ++ P G++ + +R++ E D +V TTR +R EV G DYHFV
Sbjct 9 ARRGLLFVISSPSGAGKSTIARRIL-AEDDEIHLSVSVTTRPKRPGEVDGVDYHFVDVPT 67
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI- 594
F+ +A + +E N YGT V ++++ G+ L + Q + L I
Sbjct 68 FKKMVAENQLLEWAHVFDNRYGTPRAPVEEMLHKGQDVLFDIDWQGAQQLWQQASGDTIR 127
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
++I PPS E L L G + + + + E+ +G +D ++N D+D+ ++
Sbjct 128 VYILPPSFEELERRLRGRGTDSEEVIQKRMARAASEISHWDG--YDYVLINDDMDECVKQ 185
Query 655 L 655
+
Sbjct 186 V 186
>sp|Q2KA85|KGUA_RHIEC Guanylate kinase OS=Rhizobium etli (strain
CFN 42 / ATCC 51251) OX=347834 GN=gmk PE=3 SV=1
Length=220
Score = 68.2 bits (165), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 50/187 (27%), Positives = 86/187 (46%), Gaps = 4/187 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
Q A R +++ P G++ + + L+ +K +V TTR RR EV G YHF S
Sbjct 10 QIARRGLMLVISSPSGAGKSTIARTLLETDK-HIGLSVSVTTRPRRPSEVEGVHYHFKSV 68
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ FE + +E E N YGT + V Q + G+ L + Q + L+
Sbjct 69 REFERLRDSDALLEWAEVHGNFYGTPREPVEQAMAEGRDMLFDIDWQGAQQLQEKMSADV 128
Query 594 I-IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAY 652
+ IF+ PP+ L++ L + ++ EE+ + E + +D IVN DL+ A+
Sbjct 129 VSIFVLPPTMTELQSRLHRRAED--SEEVIQTRLANSRAEIAHWREYDYVIVNDDLNTAF 186
Query 653 QELLRLI 659
+ ++
Sbjct 187 DAVQSIV 193
>sp|Q1LTY3|KGUA_BAUCH Guanylate kinase OS=Baumannia cicadellinicola
subsp. Homalodisca coagulata OX=374463 GN=gmk PE=3 SV=1
Length=204
Score = 67.8 bits (164), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 56/185 (30%), Positives = 89/185 (48%), Gaps = 15/185 (8%)
Query 483 ILIGPQNCGQNELRQRLMNKEK---DRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
I+ P G++ L Q L+ ++ ++ HTTR+ R E+ G+ Y+F+S + FE
Sbjct 4 IISAPSGTGKSSLLQALLRTKRLPLHEIRISISHTTRAMRPGEINGQHYYFISVEEFEKL 63
Query 540 IAAGKFIEHGEFEKNLYGT---SIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
I F+E+ + YGT +DS+ +INS I LL + Q K + IF
Sbjct 64 IDQDAFLEYARVFNHYYGTLRQEVDSI--LINSVDI-LLDIDWQGAKQIYAIRKDVRSIF 120
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQE 654
I PPS++ L L K G++ + + I + EM HY +D I+N D A +
Sbjct 121 IIPPSKDELHRRLHKRGQDQEEVINQRISQAVAEM----IHYTEYDYLIINDDFHTALSD 176
Query 655 LLRLI 659
L +I
Sbjct 177 LNTII 181
>sp|Q5H3S2|KGUA_XANOR Guanylate kinase OS=Xanthomonas oryzae pv.
oryzae (strain KACC10331 / KXO85) OX=291331 GN=gmk PE=3 SV=1
Length=203
Score = 67.8 bits (164), Expect = 1e-11, Method: Composition-based stats.
Identities = 47/173 (27%), Positives = 83/173 (48%), Gaps = 3/173 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I+ P G++ + + ++ + A ++ T+R+ R E YHFVS + F+ IAA
Sbjct 7 IVAAPSGAGKSSIVNATLARDP-KIALSISFTSRAPRPGERHSEHYHFVSAEEFQGMIAA 65
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
G F E+ + GT+ SV + +G LL + Q + +R +FI PPS+
Sbjct 66 GDFFEYALVHGDWKGTARQSVEPQLAAGHDVLLEIDWQGARQVRQKVPDAVSVFILPPSR 125
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
+ L + K G++ + + + + + RE E + FD I+N D A E+
Sbjct 126 QALDERMRKRGQDSE-DVMAQRLAAARE-EMLHFEEFDYVIINETFDTAVSEM 176
>sp|Q2P6N0|KGUA_XANOM Guanylate kinase OS=Xanthomonas oryzae pv.
oryzae (strain MAFF 311018) OX=342109 GN=gmk PE=3 SV=1
Length=203
Score = 67.8 bits (164), Expect = 1e-11, Method: Composition-based stats.
Identities = 47/173 (27%), Positives = 83/173 (48%), Gaps = 3/173 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I+ P G++ + + ++ + A ++ T+R+ R E YHFVS + F+ IAA
Sbjct 7 IVAAPSGAGKSSIVNATLARDP-KIALSISFTSRAPRPGERHSEHYHFVSAEEFQGMIAA 65
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
G F E+ + GT+ SV + +G LL + Q + +R +FI PPS+
Sbjct 66 GDFFEYALVHGDWKGTARQSVEPQLAAGHDVLLEIDWQGARQVRQKVPDAVSVFILPPSR 125
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
+ L + K G++ + + + + + RE E + FD I+N D A E+
Sbjct 126 QALDERMRKRGQDSE-DVMAQRLAAARE-EMLHFEEFDYVIINETFDTAVSEM 176
>sp|Q3ZWD8|KGUA_DEHMC Guanylate kinase OS=Dehalococcoides mccartyi
(strain CBDB1) OX=255470 GN=gmk PE=3 SV=1
Length=206
Score = 67.8 bits (164), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 49/185 (26%), Positives = 86/185 (46%), Gaps = 7/185 (4%)
Query 479 KRPIILI--GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
++P++LI GP G++ + R M + K V TTR +R+ E G DY+F+ F
Sbjct 11 EKPLLLIVSGPSGVGKDAVLAR-MKERKLPLTYIVTTTTRPKRETETEGVDYNFIRPAEF 69
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I+ + +E N YG +RQ ++ G ++ + Q +++ IF
Sbjct 70 QELISQNELLEWANVYGNFYGVPKAPIRQALSRGSDVIVKVDVQGAASIKKIVPNAVFIF 129
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVN--SDLDKAYQE 654
+ PP + L L + PE LR + T +E FD +VN ++D A +E
Sbjct 130 LMPPDMDELTRRL-EHRLTESPESLRRRL-ATAPLEIEKLPDFDYVVVNPEGEIDNAVRE 187
Query 655 LLRLI 659
++ +I
Sbjct 188 IMSII 192
>sp|Q8D2E8|KGUA_WIGBR Guanylate kinase OS=Wigglesworthia glossinidia
brevipalpis OX=36870 GN=gmk PE=3 SV=1
Length=207
Score = 67.4 bits (163), Expect = 2e-11, Method: Composition-based stats.
Identities = 50/175 (29%), Positives = 81/175 (46%), Gaps = 3/175 (2%)
Query 486 GPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGK 544
P G++ L + +N F ++ HTTR+ R +E+ G+DY F+S++ F+ I K
Sbjct 11 APSGTGKSSLIKTFLNTNLGMNFRLSISHTTRNIRSEEIEGKDYFFISKEKFKKMIFEKK 70
Query 545 FIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQER 604
FIE+ N YGTS V+ I S + + +K ++ K IFI PPS+
Sbjct 71 FIEYTYSFNNYYGTSFKEVKNKIKSNFSLFFDVNYKGVKKIKEFIPKLISIFILPPSKLD 130
Query 605 LRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
L L N EL + K ++ N Y D ++N D + ++ +I
Sbjct 131 LLKRLYNR-YNSNEFELNKRFYKYKKDILNYNKY-DFILINRDFNNTLNKIKTII 183
>sp|Q39IL2|KGUA_BURL3 Guanylate kinase OS=Burkholderia lata (strain
ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194
/ 383) OX=482957 GN=gmk PE=3 SV=1
Length=227
Score = 68.2 bits (165), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 46/174 (26%), Positives = 82/174 (47%), Gaps = 3/174 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ P G++ L L++K+ D ++ +TTR R E G+ YHF + + F A
Sbjct 24 FMVVAPSGAGKSTLVNALLSKDSD-ICLSISYTTRKPRPGEQDGQHYHFTTVEDFRTRHA 82
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
A +F+E E N YGTS + + + +G LL + Q ++ IFI PPS
Sbjct 83 AHEFLESAEVHGNYYGTSRVWIEEQMKNGHDVLLEIDWQGALQVKKQFRNAVGIFILPPS 142
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
+ L L K G++ R ++ E+ + + ++N + ++A EL
Sbjct 143 LDALEERLKKRGQDEPKVITRRLLAAGSEIA--HAPEAEYVVINENFERALAEL 194
>sp|Q7VKP3|KGUA_HAEDU Guanylate kinase OS=Haemophilus ducreyi
(strain 35000HP / ATCC 700724) OX=233412 GN=gmk PE=3 SV=1
Length=206
Score = 67.4 bits (163), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 49/176 (28%), Positives = 74/176 (42%), Gaps = 7/176 (4%)
Query 483 ILIGPQNCGQNELRQRLM-NKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
IL P G++ L L+ + + ++ HTTR R E G Y+F FE+ I
Sbjct 7 ILSAPSGAGKSSLINALLADLPRTEVQLSISHTTRQPRVGETHGIHYYFTEHHEFESLIE 66
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G F+E + YGTS+ + + + G L + Q + +R IFI PPS
Sbjct 67 QGHFLEWARVFDHYYGTSLPMIERSLAQGIDVFLDIDWQGARQIREKVPNVKTIFILPPS 126
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQEL 655
+ L L G++ L I ++ + HY FD I+N A EL
Sbjct 127 RAELEKRLVGRGQD----SLETIAKRMEQAVSEMTHYNEFDYVIINDQFKTALTEL 178
>sp|P60556|KGUA_RHOPA Guanylate kinase OS=Rhodopseudomonas palustris
(strain ATCC BAA-98 / CGA009) OX=258594 GN=gmk PE=3 SV=1
Length=220
Score = 67.4 bits (163), Expect = 2e-11, Method: Composition-based stats.
Identities = 51/180 (28%), Positives = 88/180 (49%), Gaps = 8/180 (4%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
+L P G+ L R++ ++ +V TTR R EV GRDY+FV R F+ + A
Sbjct 20 VLSSPSGAGKTTL-SRMLVEQMPGLQMSVSATTRPMRPGEVDGRDYYFVDRPKFDEMVGA 78
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR---TQSLKTLRNSDLKPYIIFIAP 599
G+F+E N YGT V + G+ L + TQ L++ SD+ +FI P
Sbjct 79 GEFLEWANVFDNRYGTPRAPVEAALAVGRDVLFDIDWQGTQQLRSRAGSDVVS--VFILP 136
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
PS + L L ++ E +R ++K + E ++ +D +VN ++ A++ + ++
Sbjct 137 PSVQALEHRLHTRAQDSH-EVIRGRMKKAGD-EMSHFDAYDYIVVNDNIGVAFESVRSIL 194
>sp|Q9ZCH7|KGUA_RICPR Guanylate kinase OS=Rickettsia prowazekii
(strain Madrid E) OX=272947 GN=gmk PE=3 SV=1
Length=197
Score = 66.6 bits (161), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 46/183 (25%), Positives = 91/183 (50%), Gaps = 3/183 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N+ IIL P G++ L + L+ K + ++ TTR R EV G +Y+F S + F
Sbjct 5 NKGLIIILSSPSGTGKSSLAKELL-KIDNNLRLSISVTTRKPRLGEVDGINYYFKSDREF 63
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ + KF+E+ + + YGT + V+ ++ G L + Q +++++ + IF
Sbjct 64 KTLVKQNKFLEYAKIYNDYYGTPKEYVKMLLKQGFDVLFDIDWQGVRSIKKNTNNVITIF 123
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS E L L + EE ++ ++ + E ++ + +D ++N D + +++
Sbjct 124 ILPPSIEILEQRLRNRATD--NEETIKLRMQSAQNEISHANEYDYVVINDDFSQTLKKIH 181
Query 657 RLI 659
+I
Sbjct 182 EII 184
>sp|Q8NQ42|KGUA_CORGL Guanylate kinase OS=Corynebacterium glutamicum
(strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318
/ LMG 3730 / NCIMB 10025) OX=196627 GN=gmk PE=3 SV=2
Length=190
Score = 66.6 bits (161), Expect = 3e-11, Method: Composition-based stats.
Identities = 55/180 (31%), Positives = 85/180 (47%), Gaps = 9/180 (5%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
R +IL GP G++ + RL N + + S V TTR+ R EV GRDY +V+ Q F+
Sbjct 9 RLVILAGPSAVGKSTVVDRLRNDVPNLYFS-VSMTTRAPRPGEVDGRDYFYVTAQEFQDK 67
Query 540 IAAGKFIE----HGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
I G+ +E HG +++ GT V + +G+ L+ + + + + I
Sbjct 68 IDCGEMLEWADIHGGLQRS--GTPAGPVNEARQNGRPVLVEVDLAGARNIASLIPDAETI 125
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+APPS E L L G + R +E RE E F I+N D+D A + +
Sbjct 126 FLAPPSWEVLVERLTGRGTESEDVIARR-LETARE-ELAAQSEFKHVIINDDVDTAVKAI 183
>sp|Q83GE3|KGUA_TROWT Guanylate kinase OS=Tropheryma whipplei
(strain Twist) OX=203267 GN=gmk PE=3 SV=2
Length=193
Score = 65.9 bits (159), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 45/181 (25%), Positives = 88/181 (49%), Gaps = 4/181 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I+ GP G+ + L K + ++ TTR RD E G DY+FV+ + F+ + +
Sbjct 16 IVAGPTAVGKGTVISHL-RKCHPQVKVSISATTREPRDSERDGIDYYFVTDEVFDCMVRS 74
Query 543 GKFIEHGEFEK-NLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+ +E + YGT + V +++++G+ +L + Q ++ +R + + PP+
Sbjct 75 GQMLEWATVHGLHKYGTPKEEVERLLHTGQPVILEIDLQGMRKVRKILPAVRTVILLPPA 134
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINK 661
+ L + + G + E + +E+E FD IVN+D++ A EL +N+
Sbjct 135 WDDLICRIKRRGSESQDEIDARLATAKKELEAIG--EFDYKIVNADVEIAANELWLAMNR 192
Query 662 L 662
+
Sbjct 193 V 193
>sp|Q83HT8|KGUA_TROW8 Guanylate kinase OS=Tropheryma whipplei
(strain TW08/27) OX=218496 GN=gmk PE=3 SV=1
Length=193
Score = 65.9 bits (159), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 45/181 (25%), Positives = 88/181 (49%), Gaps = 4/181 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I+ GP G+ + L K + ++ TTR RD E G DY+FV+ + F+ + +
Sbjct 16 IVAGPTAVGKGTVISHL-RKCHPQVKVSISATTREPRDSERDGIDYYFVTDEVFDCMVRS 74
Query 543 GKFIEHGEFEK-NLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+ +E + YGT + V +++++G+ +L + Q ++ +R + + PP+
Sbjct 75 GQMLEWATVHGLHKYGTPKEEVERLLHTGQPVILEIDLQGMRKVRKILPAVRTVILLPPA 134
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINK 661
+ L + + G + E + +E+E FD IVN+D++ A EL +N+
Sbjct 135 WDDLICRIKRRGSESQDEIDARLATAKKELEAIG--EFDYKIVNADVEIAANELWLAMNR 192
Query 662 L 662
+
Sbjct 193 V 193
>sp|Q2SY72|KGUA_BURTA Guanylate kinase OS=Burkholderia thailandensis
(strain ATCC 700388 / DSM 13276 / CCUG 48851 / CIP 106301
/ E264) OX=271848 GN=gmk PE=3 SV=1
Length=227
Score = 66.6 bits (161), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 46/174 (26%), Positives = 81/174 (47%), Gaps = 3/174 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ P G++ L L++K+ + ++ +TTR R E G+ YHF + + F A A
Sbjct 24 FMVVAPSGAGKSTLVNALLSKDPE-ICLSISYTTRKPRSGEQDGQHYHFTTVEDFRARHA 82
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+ +F+E E N YGTS + + + SG LL + Q + ++ IFI PPS
Sbjct 83 SHEFLESAEVHGNYYGTSRVWIEEQMKSGHDVLLEIDWQGAQQVKKQFRNAVGIFILPPS 142
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
L L K G++ R ++ E+ + + ++N + A EL
Sbjct 143 LAALEERLKKRGQDEPNVITRRLLAAGSEIA--HAAEAEYVVINETFEHALAEL 194
>sp|Q9QXY1|ZO3_MOUSE Tight junction protein ZO-3 OS=Mus musculus
OX=10090 GN=Tjp3 PE=1 SV=1
Length=905
Score = 69.7 bits (169), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 97/450 (22%), Positives = 178/450 (40%), Gaps = 89/450 (20%)
Query 254 VKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
++V K I L N++ + +S + G A+ G+ EGDE+L++NG+ R
Sbjct 369 TRVVSFPKGASIGLRLAGGNDV-GIFVSGVQAGSPADGQGI-QEGDEILQVNGMPFRNLT 426
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKET------VIHVKAHFDYDPSDDPYVPCR 367
E L + L+ + + + +++ HF+ +PS PY
Sbjct 427 REEAVQFLLGLPPGEDMELVTQSKTGHSLRRWSQSRVGDSFYIRTHFELEPS-PPY---- 481
Query 368 ELGLSFQKGDILHVISQEDP------------NWWQAYREGDEDNQPLAGLVPGKSFQQQ 415
GL F +GD+ HV+ P W A R G + + G++P +S +Q
Sbjct 482 --GLGFTRGDVFHVVDTLYPGSGPGHGHSSHGGLWLAARMGRDLREQERGVIPNQSRAEQ 539
Query 416 REAMKQTIEEDK-EPEKS------GKLWCAKKNKKKRKKVLYNANKNDDYDNEEILT--- 465
+++ P S + W + ++ KK ++ D LT
Sbjct 540 LASLEAAQRAAGVGPGASVGSNPRAEFWRLRSLRRGTKKASTQRSRED----LSALTRQG 595
Query 466 ----YEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQ 521
YE + L + A+ KRP++++GP + ++L + + F A + SR D
Sbjct 596 HYPPYERVVL--REASFKRPVVILGPV---ADIAMKKLTTEMPEEFEIA---ESMSRTD- 646
Query 522 EVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS 581
+ K I+ +D+VR + K LL + +
Sbjct 647 -------------------SPSKIIK------------LDTVRVIAERDKHALLDVTPSA 675
Query 582 LKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKP-EELREIIEKTREMEQNNGHYFD 640
++ L P +IF AP S+ L+AL +E P R + + +++++++GH F
Sbjct 676 IERLNYVQYYPIVIFCAPESRPALKAL--REWLAPASRRSSRRLYAQAQKLQKHSGHLFT 733
Query 641 TAI-VNSDLDKAYQELLRLINKLDTEPQWV 669
I ++ D YQE+ +I + P W
Sbjct 734 ATIPLHGTSDSWYQEVKAVIQQQQARPIWT 763
Score = 33.5 bits (75), Expect = 9.4, Method: Compositional matrix adjust.
Identities = 16/56 (29%), Positives = 30/56 (54%), Gaps = 0/56 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
+ I I + G A ++ L EGD +L+ING+ +++ L+ G LT +++
Sbjct 206 IFIKHITESGLAARNHGLQEGDLILQINGVSSANLSLSDTRRLIEKSEGELTLLVL 261
>sp|Q92GC9|KGUA_RICCN Guanylate kinase OS=Rickettsia conorii (strain
ATCC VR-613 / Malish 7) OX=272944 GN=gmk PE=3 SV=1
Length=229
Score = 66.6 bits (161), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 46/178 (26%), Positives = 86/178 (48%), Gaps = 3/178 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
IIL P G++ L + L+ K + ++ TTR R EV G +Y+F + FE +
Sbjct 47 IILSSPSGTGKSSLAKALL-KIDNNLRLSISATTRKPRLGEVEGINYYFKTGLEFEELVK 105
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
KF+E+ + N YGT + V ++N G L + Q ++++ + IF+ PP+
Sbjct 106 QNKFLEYAKIYDNYYGTPKEYVEMLLNQGLDVLFDIDWQGARSIKKNATNVVTIFVLPPN 165
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
E L L + EE ++ + + E ++ + +D + N D D+ +++ +I
Sbjct 166 IEVLEQRL--RNRATDNEEAIKLRMQLAQNEISHANEYDYVVTNDDFDRTLKKIHAII 221
>sp|Q8P5T7|KGUA_XANCP Guanylate kinase OS=Xanthomonas campestris
pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528
/ LMG 568 / P 25) OX=190485 GN=gmk PE=3 SV=1
Length=203
Score = 65.9 bits (159), Expect = 7e-11, Method: Composition-based stats.
Identities = 46/173 (27%), Positives = 82/173 (47%), Gaps = 3/173 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I+ P G++ + + ++ + A ++ T+R+ R E YHFVS + F+ I A
Sbjct 7 IVAAPSGAGKSSIVNATLARDP-KIALSISFTSRAPRPGERHAEHYHFVSAEEFQGMIEA 65
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
G F E+ + GT+ SV + +G LL + Q + +R +FI PPS+
Sbjct 66 GDFFEYALVHGDWKGTARQSVEPQLAAGHDVLLEIDWQGARQVRQKVPDAVSVFILPPSR 125
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
+ L + K G++ + + + + + RE E + FD I+N D A E+
Sbjct 126 QALDERMRKRGQDSE-DVMAQRLAAARE-EMLHFEEFDYVIINETFDTAVSEM 176
>sp|Q4UY41|KGUA_XANC8 Guanylate kinase OS=Xanthomonas campestris
pv. campestris (strain 8004) OX=314565 GN=gmk PE=3 SV=1
Length=203
Score = 65.9 bits (159), Expect = 7e-11, Method: Composition-based stats.
Identities = 46/173 (27%), Positives = 82/173 (47%), Gaps = 3/173 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I+ P G++ + + ++ + A ++ T+R+ R E YHFVS + F+ I A
Sbjct 7 IVAAPSGAGKSSIVNATLARDP-KIALSISFTSRAPRPGERHAEHYHFVSAEEFQGMIEA 65
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
G F E+ + GT+ SV + +G LL + Q + +R +FI PPS+
Sbjct 66 GDFFEYALVHGDWKGTARQSVEPQLAAGHDVLLEIDWQGARQVRQKVPDAVSVFILPPSR 125
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
+ L + K G++ + + + + + RE E + FD I+N D A E+
Sbjct 126 QALDERMRKRGQDSE-DVMAQRLAAARE-EMLHFEEFDYVIINETFDTAVSEM 176
>sp|Q984S9|KGUA_RHILO Guanylate kinase OS=Mesorhizobium japonicum
(strain LMG 29417 / CECT 9101 / MAFF 303099) OX=266835 GN=gmk
PE=3 SV=2
Length=218
Score = 65.9 bits (159), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 50/181 (28%), Positives = 84/181 (46%), Gaps = 6/181 (3%)
Query 478 RKRPIILI--GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
R+R ++L+ P G++ + + L+ + +V TTR RR E+ G YHF + +
Sbjct 11 RRRGLMLVLSSPSGAGKSTIARNLLESDSS-LELSVSVTTRPRRGSEIEGVHYHFRTMRE 69
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI- 594
FE + +E E N Y T + + G+ L + Q + L+ +
Sbjct 70 FERLRDSDALLEWAEVHGNCYATPREPAELALAQGRDMLFDIDWQGAQQLKEKMRADIVS 129
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFI PPS + L+A L + ++ E + E K E + +D IVN DLD+A+ E
Sbjct 130 IFILPPSMKELKARLKRRAED--QEAVIETRLKNARNEIEHWKEYDFVIVNDDLDRAFAE 187
Query 655 L 655
+
Sbjct 188 V 188
>sp|Q8PH65|KGUA_XANAC Guanylate kinase OS=Xanthomonas axonopodis
pv. citri (strain 306) OX=190486 GN=gmk PE=3 SV=1
Length=203
Score = 65.1 bits (157), Expect = 1e-10, Method: Composition-based stats.
Identities = 46/175 (26%), Positives = 79/175 (45%), Gaps = 7/175 (4%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I+ P G++ + + ++ + A ++ T+R+ R E YHFVS F+ I A
Sbjct 7 IVAAPSGAGKSSIVNATLARDP-KIALSISFTSRAPRPGERHAEHYHFVSADEFQGMIEA 65
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
G F E+ + GT+ SV + +G LL + Q + +R +FI PPS+
Sbjct 66 GDFFEYALVHGDWKGTARQSVEPQLAAGHDVLLEIDWQGARQVRQKVPDAVSVFILPPSR 125
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQEL 655
+ L + K G++ + + + EM H+ FD I+N D A E+
Sbjct 126 QALDERMRKRGQDSEVVMAQRLAAAREEML----HFEEFDYVIINETFDTAVSEM 176
>sp|Q1GXB9|KGUA_METFK Guanylate kinase OS=Methylobacillus flagellatus
(strain KT / ATCC 51484 / DSM 6875) OX=265072 GN=gmk
PE=3 SV=1
Length=202
Score = 64.7 bits (156), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 51/190 (27%), Positives = 79/190 (42%), Gaps = 5/190 (3%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+ P G+ L + L++ + + +V HTTR R E G YHFV F +
Sbjct 6 FIITAPSGAGKTSLVRALLDGD-EHIKLSVSHTTRKPRPGEEDGVHYHFVEEARFVELLN 64
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G F+E + YGTS +V + G +L + Q + +R+ IFI PPS
Sbjct 65 HGDFLESAQVHGAYYGTSQSTVNSALAEGYDLILEIDWQGAQQVRSLYADAISIFILPPS 124
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI-- 659
E L L ++ R + EM FD +N + A ++L +I
Sbjct 125 MEALEQRLNNRAQDSAEVIARRLAAAREEMRHVTE--FDYVTINDRFEHALEDLRAIIRS 182
Query 660 NKLDTEPQWV 669
+L E Q +
Sbjct 183 QRLRREKQLI 192
>sp|Q1QKV7|KGUA_NITHX Guanylate kinase OS=Nitrobacter hamburgensis
(strain DSM 10229 / NCIMB 13809 / X14) OX=323097 GN=gmk
PE=3 SV=1
Length=219
Score = 64.7 bits (156), Expect = 2e-10, Method: Composition-based stats.
Identities = 48/178 (27%), Positives = 83/178 (47%), Gaps = 4/178 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
+L P G+ L RL+ + + + +V TTR R EV GRDY FV + F +
Sbjct 19 VLSSPSGAGKTTL-SRLLIERVEGLSLSVSATTRPMRPGEVDGRDYRFVDKATFAVMVKC 77
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-IFIAPPS 601
+ +E N YGT V ++SG+ L + Q + LR + +FI PPS
Sbjct 78 DELLEWATVFDNRYGTPRAPVEAALSSGRDVLFDIDWQGTQQLREKARADVVSVFILPPS 137
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
L L ++ E +R +++ E ++ +D ++N D+D+A+ E+ ++
Sbjct 138 ATDLERRLHTRAQDSD-EVIRGRMDRAAH-ELSHWAEYDYIVINQDIDEAFAEVQSIL 193
>sp|A0A0G2K2P5|ZO1_RAT Tight junction protein ZO-1 OS=Rattus norvegicus
OX=10116 GN=Tjp1 PE=1 SV=1
Length=1765
Score = 68.2 bits (165), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 91/437 (21%), Positives = 182/437 (42%), Gaps = 77/437 (18%)
Query 253 TVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
++K+V+ K + L N++ + ++ +++ A K GL EGD++L +N ++
Sbjct 421 SMKLVKFRKGDSVGLRLAGGNDV-GIFVAGVLEDSPAAKEGL-EEGDQILRVNNVDFTNI 478
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV-------IHVKAHFDYDPSDDPYVP 365
E L D+ ++ Q K + V +++ HF+Y+ + PY
Sbjct 479 IREEAVLFLLDLPKGEEVTIL--AQKKKDVYRRIVESDVGDSFYIRTHFEYE-KESPY-- 533
Query 366 CRELGLSFQKGDILHVIS---QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQT 422
GLSF KG++ V+ W A R G + G+VP K+ +Q +++ T
Sbjct 534 ----GLSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGIVPNKNRAEQLASVQYT 589
Query 423 IEEDKEPEKSGKLW------CAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPA 476
+ + +++ W +K+N +K ++ L + E + E
Sbjct 590 LPKTAGGDRA-DFWRFRGLRSSKRNLRKSREDLSAQPVQTKFPAYERVVLREAGFL---- 644
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
RP+ + GP + R++L +E D + A + + AG D+
Sbjct 645 ---RPVTIFGPI---ADVAREKLAREEPDIYQIA-------KSEPRDAGTDHR------- 684
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
++G H +++Q+I+ K LL + ++ L + P ++F
Sbjct 685 ----SSGIIRLH-------------TIKQIIDQDKHALLDVTPNAVDRLNYAQWYPIVVF 727
Query 597 IAPPSQERLRAL---LAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAI-VNSDLDKAY 652
+ P S++ ++ + L E + + R++ E++ ++ +NN H F T I +NS D Y
Sbjct 728 LNPDSKQGVKTMRMRLCPESR----KSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWY 783
Query 653 QELLRLINKLDTEPQWV 669
L I + + WV
Sbjct 784 GALKEAIQQQQNQLVWV 800
Score = 35.4 bits (80), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 27/110 (25%), Positives = 44/110 (40%), Gaps = 5/110 (5%)
Query 223 AHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISR 282
A D+ A ++ L P +D R S V +V+ K + L + +
Sbjct 156 ARDRSASRDRSLSPRSDRRSVASSQPAKPTKVTLVKSRKNEEYGLRLASH-----IFVKE 210
Query 283 IVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
I + A + G + EGD VL+ING + + L+ G L V+
Sbjct 211 ISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVV 260
Score = 33.9 bits (76), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 15/33 (45%), Positives = 22/33 (67%), Gaps = 2/33 (6%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
S++IS ++KGG AE G L E D V +NG+ +
Sbjct 53 SIVISDVLKGGPAE--GQLQENDRVAMVNGVSM 83
>sp|Q2SSR8|KGUA_MYCCT Guanylate kinase OS=Mycoplasma capricolum
subsp. capricolum (strain California kid / ATCC 27343 / NCTC
10154) OX=340047 GN=gmk PE=3 SV=1
Length=297
Score = 65.9 bits (159), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 37/128 (29%), Positives = 57/128 (45%), Gaps = 0/128 (0%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ + II+ GP G+ + L+ R +V TTR R+ E+ G +Y FVS + F
Sbjct 3 KGKMIIISGPSGVGKGSVNGELLQNPDLRLKYSVSMTTRKPRNGEINGVNYFFVSNEEFA 62
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I + IE+ F N YGT V Q + G +L + + N + IF+
Sbjct 63 KAIVNDELIEYAHFVGNSYGTPRKYVEQELKKGNNVILEIEVDGATQVLNKEANVLSIFL 122
Query 598 APPSQERL 605
PP+ L
Sbjct 123 MPPNLTEL 130
>sp|Q491W5|KGUA_BLOPB Guanylate kinase OS=Blochmannia pennsylvanicus
(strain BPEN) OX=291272 GN=gmk PE=3 SV=1
Length=212
Score = 64.3 bits (155), Expect = 2e-10, Method: Composition-based stats.
Identities = 39/149 (26%), Positives = 78/149 (52%), Gaps = 7/149 (5%)
Query 510 AVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINS 569
++ +TTR +R E+ G+DY+F+S++ F+ I F E+ + YGT+ + ++N+
Sbjct 38 SISYTTRIKRPGEIHGKDYYFISKKKFKYMIDKNMFFEYAMIFNHYYGTAKTDIETMLNT 97
Query 570 GKICLLSLRTQSLKTLRNSDLKP-YIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKT 628
G +L++ + + +R+ K Y IFI PPS++ L L G++ + + I+ +
Sbjct 98 GIHIVLNIDWKGAQQIRSKISKNIYTIFILPPSKKELARRLYLRGEDTE----KVIVARM 153
Query 629 REMEQNNGHY--FDTAIVNSDLDKAYQEL 655
+ H+ +D I+N + + A L
Sbjct 154 GQAMDEISHFKEYDYIIINDNFNIALMHL 182
>sp|Q0C093|KGUA_HYPNA Guanylate kinase OS=Hyphomonas neptunium
(strain ATCC 15444) OX=228405 GN=gmk PE=3 SV=1
Length=217
Score = 64.3 bits (155), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 52/182 (29%), Positives = 84/182 (46%), Gaps = 10/182 (5%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++L P G+ L + L+ + D ++ TTR R EV G DY+F + F I
Sbjct 18 LVLSSPSGAGKTTLSRMLLEEFGD-VKLSISATTRPPRPNEVHGEDYYFKTPDEFHRMIE 76
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-IFIAPP 600
+F+E YGT + +G+ L + Q L + + +FI PP
Sbjct 77 RREFLEWAHVFDKHYGTPKADTVARLEAGEDVLFDVDWQGADALHDQMPNDVVSVFILPP 136
Query 601 SQERLRA-LLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELLR 657
S E L+A L+ + G P EL + + + ++ H+ +D IVN DL+ AYQ L R
Sbjct 137 SIEALQARLMGRPGSTP---EL--VARRMEDAKREIMHWRRYDYVIVNDDLNVAYQRLKR 191
Query 658 LI 659
++
Sbjct 192 IL 193
>sp|Q7VXZ3|KGUA_BORPE Guanylate kinase OS=Bordetella pertussis
(strain Tohama I / ATCC BAA-589 / NCTC 13251) OX=257313 GN=gmk
PE=3 SV=2
Length=215
Score = 63.9 bits (154), Expect = 3e-10, Method: Composition-based stats.
Identities = 47/192 (24%), Positives = 87/192 (45%), Gaps = 3/192 (2%)
Query 469 MSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDY 528
MS A +++ P G++ L + L++++ S + TTR+ R E GR+Y
Sbjct 1 MSFLSMSAPSGNVFMVVAPSGAGKSSLVRALLDRDPSLVLS-ISCTTRAPRPGEQDGREY 59
Query 529 HFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS 588
FV + F A + +E E N YGT D + + +G LL + Q + ++
Sbjct 60 RFVDQAEFARLRDAQQLLEWAEVHGNFYGTPRDRIDEATRAGHDVLLEIDWQGARQVKQR 119
Query 589 DLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDL 648
+ IF+ PPS + L + L G++ R ++ E+ + + I+N +
Sbjct 120 YPEAIGIFVLPPSIDELESRLKARGQDAPQVIARRLLAAGGEIA--HAPECEYVIINQEF 177
Query 649 DKAYQELLRLIN 660
A EL+++I+
Sbjct 178 SVALTELVQIIS 189
>sp|Q7W6B2|KGUA_BORPA Guanylate kinase OS=Bordetella parapertussis
(strain 12822 / ATCC BAA-587 / NCTC 13253) OX=257311 GN=gmk
PE=3 SV=1
Length=215
Score = 63.9 bits (154), Expect = 3e-10, Method: Composition-based stats.
Identities = 47/192 (24%), Positives = 87/192 (45%), Gaps = 3/192 (2%)
Query 469 MSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDY 528
MS A +++ P G++ L + L++++ S + TTR+ R E GR+Y
Sbjct 1 MSFLSMSAPSGNVFMVVAPSGAGKSSLVRALLDRDPSLVLS-ISCTTRAPRPGEQDGREY 59
Query 529 HFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS 588
FV + F A + +E E N YGT D + + +G LL + Q + ++
Sbjct 60 RFVDQAEFARLRDAQQLLEWAEVHGNFYGTPRDRIDEATRAGHDVLLEIDWQGARQVKQR 119
Query 589 DLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDL 648
+ IF+ PPS + L + L G++ R ++ E+ + + I+N +
Sbjct 120 YPEAIGIFVLPPSIDELESRLKARGQDAPQVIARRLLAAGGEIA--HAPECEYVIINQEF 177
Query 649 DKAYQELLRLIN 660
A EL+++I+
Sbjct 178 SVALTELVQIIS 189
>sp|Q7WI80|KGUA_BORBR Guanylate kinase OS=Bordetella bronchiseptica
(strain ATCC BAA-588 / NCTC 13252 / RB50) OX=257310 GN=gmk
PE=3 SV=1
Length=215
Score = 63.9 bits (154), Expect = 3e-10, Method: Composition-based stats.
Identities = 47/192 (24%), Positives = 87/192 (45%), Gaps = 3/192 (2%)
Query 469 MSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDY 528
MS A +++ P G++ L + L++++ S + TTR+ R E GR+Y
Sbjct 1 MSFLSMSAPSGNVFMVVAPSGAGKSSLVRALLDRDPSLVLS-ISCTTRAPRPGEQDGREY 59
Query 529 HFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS 588
FV + F A + +E E N YGT D + + +G LL + Q + ++
Sbjct 60 RFVDQAEFARLRDAQQLLEWAEVHGNFYGTPRDRIDEATRAGHDVLLEIDWQGARQVKQR 119
Query 589 DLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDL 648
+ IF+ PPS + L + L G++ R ++ E+ + + I+N +
Sbjct 120 YPEAIGIFVLPPSIDELESRLKARGQDAPQVIARRLLAAGGEIA--HAPECEYVIINQEF 177
Query 649 DKAYQELLRLIN 660
A EL+++I+
Sbjct 178 SVALTELVQIIS 189
>sp|Q3BPS0|KGUA_XANC5 Guanylate kinase OS=Xanthomonas campestris
pv. vesicatoria (strain 85-10) OX=316273 GN=gmk PE=3 SV=1
Length=203
Score = 63.5 bits (153), Expect = 3e-10, Method: Composition-based stats.
Identities = 46/173 (27%), Positives = 81/173 (47%), Gaps = 3/173 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I+ P G++ + + ++ + A ++ T+R+ R E YHFVS F+ I A
Sbjct 7 IVAAPSGAGKSSIVNATLARDP-KIALSISFTSRAPRPGERHAEHYHFVSADEFQGMIEA 65
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
G F E+ + GT+ SV + +G LL + Q + +R +FI PPS+
Sbjct 66 GDFFEYALVHGDWKGTARQSVEPQLAAGHDVLLEIDWQGARQVRQKVPDAVSVFILPPSR 125
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
+ L + K G++ + + + + + RE E + FD I+N D A E+
Sbjct 126 QALDERMRKRGQDSE-DVMAQRLAAARE-EMLHFEEFDYVIINETFDIAVAEM 176
>sp|Q3SRZ7|KGUA_NITWN Guanylate kinase OS=Nitrobacter winogradskyi
(strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846
/ Nb-255) OX=323098 GN=gmk PE=3 SV=1
Length=219
Score = 63.9 bits (154), Expect = 3e-10, Method: Composition-based stats.
Identities = 49/178 (28%), Positives = 83/178 (47%), Gaps = 4/178 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
+L P G+ L RL+ + + + +V TTR R EV GRDY FV + F A +
Sbjct 19 VLSSPSGAGKTTL-SRLLIERVEGLSLSVSATTRPMRPGEVDGRDYAFVDEKTFAAMVER 77
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-IFIAPPS 601
+E N YGT V ++SG+ L + Q + LR + +FI PPS
Sbjct 78 NDLLEWAHVFDNHYGTPRAPVDAALSSGRDVLFDIDWQGTQQLREKARDDVVSVFILPPS 137
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
L L ++ + +RE + + E ++ +D ++N D+D+A+ E+ ++
Sbjct 138 AADLERRLHTRAQDSD-DVIRERMARAAH-EVSHWAEYDYIVINRDIDEAFAEVQSIL 193
>sp|Q07157|ZO1_HUMAN Tight junction protein ZO-1 OS=Homo sapiens
OX=9606 GN=TJP1 PE=1 SV=3
Length=1748
Score = 67.4 bits (163), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 89/437 (20%), Positives = 180/437 (41%), Gaps = 77/437 (18%)
Query 253 TVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
++K+V+ K + L N++ + ++ +++ A K GL EGD++L +N ++
Sbjct 421 SMKLVKFRKGDSVGLRLAGGNDV-GIFVAGVLEDSPAAKEGL-EEGDQILRVNNVDFTNI 478
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV-------IHVKAHFDYDPSDDPYVP 365
E L D+ ++ Q K + V +++ HF+Y+ + PY
Sbjct 479 IREEAVLFLLDLPKGEEVTIL--AQKKKDVYRRIVESDVGDSFYIRTHFEYE-KESPY-- 533
Query 366 CRELGLSFQKGDILHVIS---QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQT 422
GLSF KG++ V+ W A R G + G++P K+ +Q +++ T
Sbjct 534 ----GLSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGIIPNKNRAEQLASVQYT 589
Query 423 IEEDKEPEKSGKLW------CAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPA 476
+ + +++ W +K+N +K ++ L + E + E
Sbjct 590 LPKTAGGDRA-DFWRFRGLRSSKRNLRKSREDLSAQPVQTKFPAYERVVLREAGFL---- 644
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
RP+ + GP + R++L +E D + A + DQ +G + R
Sbjct 645 ---RPVTIFGPI---ADVAREKLAREEPDIYQIAKSEPRDAGTDQRSSG-----IIR--- 690
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ +++Q+I+ K LL + ++ L + P ++F
Sbjct 691 -----------------------LHTIKQIIDQDKHALLDVTPNAVDRLNYAQWYPIVVF 727
Query 597 IAPPSQERLRAL---LAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAI-VNSDLDKAY 652
+ P S++ ++ + L E + + R++ E++ ++ +NN H F T I +NS D Y
Sbjct 728 LNPDSKQGVKTMRMRLCPESR----KSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWY 783
Query 653 QELLRLINKLDTEPQWV 669
L I + + WV
Sbjct 784 GALKEAIQQQQNQLVWV 800
Score = 35.4 bits (80), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 27/112 (24%), Positives = 44/112 (39%), Gaps = 5/112 (4%)
Query 221 LLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVII 280
+ D+ A +E L P +D R S V +V+ K + L + +
Sbjct 154 IWPRDRSASRERSLSPRSDRRSVASSQPAKPTKVTLVKSRKNEEYGLRLASH-----IFV 208
Query 281 SRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
I + A + G + EGD VL+ING + + L+ G L V+
Sbjct 209 KEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVV 260
Score = 33.9 bits (76), Expect = 7.3, Method: Compositional matrix adjust.
Identities = 15/33 (45%), Positives = 22/33 (67%), Gaps = 2/33 (6%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
S++IS ++KGG AE G L E D V +NG+ +
Sbjct 53 SIVISDVLKGGPAE--GQLQENDRVAMVNGVSM 83
>sp|Q68VY3|KGUA_RICTY Guanylate kinase OS=Rickettsia typhi (strain
ATCC VR-144 / Wilmington) OX=257363 GN=gmk PE=3 SV=1
Length=197
Score = 63.5 bits (153), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 43/178 (24%), Positives = 87/178 (49%), Gaps = 3/178 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
IIL P G++ L + L+ K + ++ TTR R EV G +Y+F + F+ +
Sbjct 10 IILSSPSGTGKSSLAKELL-KIDNNLRLSISVTTRKPRLGEVDGINYYFKTDLEFKTLVK 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
KF+E+ + + YGT + V+ ++ G L + Q +++++ + IF+ PPS
Sbjct 69 QNKFLEYAKIYNDYYGTPKEYVKMLLKQGLDVLFDIDWQGVRSIKKNTNNVVTIFVLPPS 128
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
E L L + EE ++ ++ + E + + +D ++N D + +++ +I
Sbjct 129 LEILEQRLRNRATD--NEETIKLRMQSAQHEISYANEYDYVVINDDFGQTLKKIHEII 184
>sp|Q89MV4|KGUA_BRADU Guanylate kinase OS=Bradyrhizobium diazoefficiens
(strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC
14792 / USDA 110) OX=224911 GN=gmk PE=3 SV=1
Length=219
Score = 63.9 bits (154), Expect = 4e-10, Method: Composition-based stats.
Identities = 49/178 (28%), Positives = 83/178 (47%), Gaps = 4/178 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
+L P G+ L RL+ + +V TTR R EV GRDY FV + FEA +
Sbjct 19 VLSSPSGAGKTTL-SRLLIERMPGLRMSVSATTRPMRPGEVDGRDYLFVDKPRFEAMVRD 77
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-IFIAPPS 601
+ +E N YGT V +++G+ L + Q + LR + +FI PPS
Sbjct 78 DELLEWATVFDNRYGTPRAPVEAALSAGQDVLFDIDWQGTQQLREKARADVVSVFILPPS 137
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
L L ++ E +R+ + + E ++ +D ++N D+D+A+ E+ ++
Sbjct 138 AGDLEKRLHSRAQDSD-EVIRKRMSRASH-EMSHWAEYDYIVINHDVDEAFAEVQSIL 193
>sp|O97758|ZO1_CANLF Tight junction protein ZO-1 OS=Canis lupus
familiaris OX=9615 GN=TJP1 PE=1 SV=1
Length=1769
Score = 67.4 bits (163), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 89/437 (20%), Positives = 180/437 (41%), Gaps = 77/437 (18%)
Query 253 TVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
++K+V+ K + L N++ + ++ +++ A K GL EGD++L +N ++
Sbjct 420 SMKLVKFRKGDSVGLRLAGGNDV-GIFVAGVLEDSPAAKEGL-EEGDQILRVNNVDFTNI 477
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV-------IHVKAHFDYDPSDDPYVP 365
E L D+ ++ Q K + V +++ HF+Y+ + PY
Sbjct 478 IREEAVLFLLDLPKGEEVTIL--AQKKKDVYRRIVESDVGDSFYIRTHFEYE-KESPY-- 532
Query 366 CRELGLSFQKGDILHVIS---QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQT 422
GLSF KG++ V+ W A R G + G++P K+ +Q +++ T
Sbjct 533 ----GLSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGIIPNKNRAEQLASVQYT 588
Query 423 IEEDKEPEKSGKLW------CAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPA 476
+ + +++ W +K+N +K ++ L + E + E
Sbjct 589 LPKTAGGDRA-DFWRFRGLRSSKRNLRKSREDLSAQPVQTKFPAYERVVLREAGFL---- 643
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
RP+ + GP + R++L +E D + A + DQ +G + R
Sbjct 644 ---RPVTIFGPI---ADVAREKLAREEPDIYQIAKSEPRDAGTDQRSSG-----IIR--- 689
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ +++Q+I+ K LL + ++ L + P ++F
Sbjct 690 -----------------------LHTIKQIIDQDKHALLDVTPNAVDRLNYAQWYPIVVF 726
Query 597 IAPPSQERLRAL---LAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAI-VNSDLDKAY 652
+ P S++ ++ + L E + + R++ E++ ++ +NN H F T I +NS D Y
Sbjct 727 LNPDSKQGVKTMRMRLCPESR----KSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWY 782
Query 653 QELLRLINKLDTEPQWV 669
L I + + WV
Sbjct 783 GALKEAIQQQQNQLVWV 799
Score = 36.2 bits (82), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 28/110 (25%), Positives = 44/110 (40%), Gaps = 5/110 (5%)
Query 223 AHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISR 282
A D+ A +E L P +D R S V +V+ K + L + +
Sbjct 155 ARDRSASRERSLSPRSDRRSVASSQPPKPTKVTLVKSRKNEEYGLRLASH-----IFVKE 209
Query 283 IVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
I + A + G + EGD VL+ING + + L+ G L V+
Sbjct 210 ISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVV 259
Score = 33.9 bits (76), Expect = 6.9, Method: Compositional matrix adjust.
Identities = 15/33 (45%), Positives = 22/33 (67%), Gaps = 2/33 (6%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
S++IS ++KGG AE G L E D V +NG+ +
Sbjct 53 SIVISDVLKGGPAE--GQLQENDRVAMVNGVSM 83
>sp|E9Q9R9|DLG5_MOUSE Disks large homolog 5 OS=Mus musculus OX=10090
GN=Dlg5 PE=1 SV=1
Length=1921
Score = 67.4 bits (163), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 89/449 (20%), Positives = 194/449 (43%), Gaps = 64/449 (14%)
Query 255 KIVRIEKARDIPLGA-TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
+IV I+K++ + LG + V ++ + A+ L GD +LE +++R +
Sbjct 1504 RIVFIKKSQ-LDLGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDMRSRT 1562
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQ----IKPPPAKETVIHVKAHFDYDPSDDPYVPCREL 369
V +V+ + +L + + +K P +++A +D +P
Sbjct 1563 VEDVYVEMLKPKDSLRLKVQYRHEEFTRVKGLPGDS--FYIRALYDRLAEVEPE------ 1614
Query 370 GLSFQKGDILHV---ISQEDPNWWQAYREGDEDNQPLA-GLVPGKSFQQQREAMKQTIEE 425
LSF+K DIL+V + Q W A+ + DE+ Q + G +P K Q + + ++ E
Sbjct 1615 -LSFKKDDILYVDDTLPQGVFGSWMAW-QLDENAQKIQRGQIPSKYVMDQEFSRRLSMSE 1672
Query 426 DKEPEKSGKLWCAKKNKKKRKKVLYNANKN---------DDYDNEEILTYEE-MSLYHQP 475
K+ + L A + R+K + + + D + N+ I +E+ +SL +Q
Sbjct 1673 VKDDNTAKTLSAAARRSFFRRKHKHKRSGSKDGKDLLALDTFSNDSIPLFEDSVSLAYQR 1732
Query 476 ANRK-----RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ RP++L+GP + +++ L+N+ +F ++
Sbjct 1733 VQKVDCTSLRPVLLLGPL---LDVVKEMLVNEAPGKFCRCPLEVMKA------------- 1776
Query 531 VSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL 590
S+QA E + F+++ + T++ S++++ + CLL + +++ L + +
Sbjct 1777 -SQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNRHCLLDIAPHAIERLHHMHI 1835
Query 591 KPYIIFIAPPSQERLRALLAKEGKNP-------KPEELREIIEKTREMEQNNGHYFDTAI 643
P +IFI S + + KE ++P +E E ++++Q YF +
Sbjct 1836 YPIVIFIRYKSAKHI-----KEQRDPVYLRDKVTQRHSKEQFETAQKIDQEYSRYFTGVV 1890
Query 644 VNSDLDKAYQELLRLINKLDTEPQWVPST 672
L ++L ++++ ++ W+P+
Sbjct 1891 QGGALSSICTQILAMVSQEQSKVLWIPAC 1919
Score = 44.3 bits (103), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 27/84 (32%), Positives = 40/84 (48%), Gaps = 3/84 (4%)
Query 250 GGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
GG+ V + I + G ++ N V + +V G A K G L GD ++ INGI +
Sbjct 713 GGKVVTPLHINLSGQKDSGISLEN---GVYAAAVVPGSPAAKEGSLAVGDRIVAINGIAL 769
Query 310 RGKDVNEVFDLLSDMHGTLTFVLI 333
K +NE LL +LT L+
Sbjct 770 DNKSLNECESLLRSCQDSLTLSLL 793
Score = 38.9 bits (89), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 23/76 (30%), Positives = 42/76 (55%), Gaps = 3/76 (4%)
Query 257 VRIEKARDIPLG-ATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVN 315
V+++K + PLG + V E V +S++ G A ++GL + GD++LE NGI +R
Sbjct 1351 VKVQKGSE-PLGISIVSGEKGGVYVSKVTLGSIAHQAGLEY-GDQLLEFNGINLRSATEQ 1408
Query 316 EVFDLLSDMHGTLTFV 331
+ ++ T+T +
Sbjct 1409 QARLIIGQQCDTITIL 1424
>sp|Q1MJ02|KGUA_RHIJ3 Guanylate kinase OS=Rhizobium johnstonii
(strain DSM 114642 / LMG 32736 / 3841) OX=216596 GN=gmk PE=3
SV=1
Length=220
Score = 63.5 bits (153), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 48/179 (27%), Positives = 82/179 (46%), Gaps = 4/179 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
Q A R +++ P G++ + + L+ ++ + +V TTR RR EV YHF S
Sbjct 10 QIARRGLMLVISSPSGAGKSTIARTLLETDR-QIGLSVSVTTRQRRPSEVEDVHYHFKSV 68
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ FE + +E E N YGT + V Q + G+ L + Q + L+
Sbjct 69 REFERLRDSDALLEWAEVHGNFYGTPREPVEQAMGEGRDMLFDIDWQGAQQLQEKMSADV 128
Query 594 I-IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
+ IF+ PP+ L++ L + ++ EE+ + E + +D IVN DL+ A
Sbjct 129 VSIFVLPPTMTELQSRLHRRAED--SEEVIQTRLANSRAEIAHWREYDYVIVNDDLNAA 185
>sp|Q1GNB4|KGUA_SPHAL Guanylate kinase OS=Sphingopyxis alaskensis
(strain DSM 13593 / LMG 18877 / RB2256) OX=317655 GN=gmk
PE=3 SV=1
Length=220
Score = 63.5 bits (153), Expect = 5e-10, Method: Composition-based stats.
Identities = 44/178 (25%), Positives = 80/178 (45%), Gaps = 4/178 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
+L P G+ + + ++ ++KD A +V TTR R E+ G YHFV F+ A
Sbjct 15 VLSSPSGAGKTTISRMMLEEDKD-IALSVSATTRPPRPGEIDGVHYHFVDTDTFKKMAAD 73
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-IFIAPPS 601
G F+E + YGT V +++ +GK L + Q + L + +F+ PP+
Sbjct 74 GAFLEWAHVFGHRYGTPRAPVEELLAAGKDVLFDIDWQGAQQLYQEAGPDVVRVFVLPPT 133
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
E L L G + + E+ +G +D ++N + + Y E++ ++
Sbjct 134 MEELERRLRARGTDSDEVIAARMARAANEISHWDG--YDYVLINDHVGECYGEVMAIL 189
>sp|P39447|ZO1_MOUSE Tight junction protein ZO-1 OS=Mus musculus
OX=10090 GN=Tjp1 PE=1 SV=2
Length=1745
Score = 67.0 bits (162), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 90/437 (21%), Positives = 182/437 (42%), Gaps = 77/437 (18%)
Query 253 TVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
++K+V+ K + L N++ + ++ +++ A K GL EGD++L +N ++
Sbjct 421 SMKLVKFRKGDSVGLRLAGGNDV-GIFVAGVLEDSPAAKEGL-EEGDQILRVNNVDFTNI 478
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV-------IHVKAHFDYDPSDDPYVP 365
E L D+ ++ Q K + V +++ HF+Y+ + PY
Sbjct 479 IREEAVLFLLDLPKGEEVTIL--AQKKKDVYRRIVESDVGDSFYIRTHFEYE-KESPY-- 533
Query 366 CRELGLSFQKGDILHVIS---QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQT 422
GLSF KG++ V+ W A R G + G++P K+ +Q +++ T
Sbjct 534 ----GLSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGIIPNKNRAEQLASVQYT 589
Query 423 IEEDKEPEKSGKLW------CAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPA 476
+ + +++ W +K+N +K ++ L + E + E
Sbjct 590 LPKTAGGDRA-DFWRFRGLRSSKRNLRKSREDLSAQPVQTKFPAYERVVLREAGFL---- 644
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
RP+ + GP + R++L +E D + A + + AG D+
Sbjct 645 ---RPVTIFGPI---ADVAREKLAREEPDIYQIA-------KSEPRDAGTDHR------- 684
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
++G H +++Q+I+ K LL + ++ L + P ++F
Sbjct 685 ----SSGIIRLH-------------TIKQIIDQDKHALLDVTPNAVDRLNYAQWYPIVVF 727
Query 597 IAPPSQERLRAL---LAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAI-VNSDLDKAY 652
+ P S++ ++ + L E + + R++ E++ ++ +NN H F T I +NS D Y
Sbjct 728 LNPDSKQGVKTMRMRLCPESR----KSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWY 783
Query 653 QELLRLINKLDTEPQWV 669
L I + + WV
Sbjct 784 GALKEAIQQQQNQLVWV 800
Score = 36.6 bits (83), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 28/110 (25%), Positives = 44/110 (40%), Gaps = 5/110 (5%)
Query 223 AHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISR 282
A D+ A +E L P +D R S V +V+ K + L + +
Sbjct 156 ARDRSASRERSLSPRSDRRSVASSQPAKPTKVTLVKSRKNEEYGLRLASH-----IFVKE 210
Query 283 IVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
I + A + G + EGD VL+ING + + L+ G L V+
Sbjct 211 ISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVV 260
Score = 33.9 bits (76), Expect = 6.9, Method: Compositional matrix adjust.
Identities = 15/33 (45%), Positives = 22/33 (67%), Gaps = 2/33 (6%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
S++IS ++KGG AE G L E D V +NG+ +
Sbjct 53 SIVISDVLKGGPAE--GQLQENDRVAMVNGVSM 83
>sp|Q8A677|KGUA_BACTN Guanylate kinase OS=Bacteroides thetaiotaomicron
(strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774
/ NCTC 10582 / VPI-5482 / E50) OX=226186 GN=gmk PE=3 SV=1
Length=204
Score = 63.2 bits (152), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 54/188 (29%), Positives = 86/188 (46%), Gaps = 15/188 (8%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
II P G++ + L+ + + A ++ T+R R E G +Y F++ + F I
Sbjct 21 IIFSAPSGSGKSTIINYLLTQNLN-LAFSISATSRPPRGTEKHGVEYFFLTPEEFRCRIE 79
Query 542 AGKFIEHGEFEKN-LYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI------ 594
+F+E+ E K+ YGT + V + + G+ + L + ++K Y
Sbjct 80 NNEFLEYEEVYKDRYYGTLKEQVEKQLEKGQNVVF-----DLDVVGGCNIKKYYGERALS 134
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IF+ PPS E LR L G + +PE + I K E E FD IVN DL+ A E
Sbjct 135 IFVQPPSIEELRCRLTGRGTD-EPEVIECRIAKA-EYEMTFAPQFDRVIVNDDLEAAKAE 192
Query 655 LLRLINKL 662
L +I +
Sbjct 193 TLEVIKEF 200
>sp|Q9PD76|KGUA_XYLFA Guanylate kinase OS=Xylella fastidiosa (strain
9a5c) OX=160492 GN=gmk PE=3 SV=1
Length=204
Score = 62.8 bits (151), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 48/175 (27%), Positives = 79/175 (45%), Gaps = 7/175 (4%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I+ G++ + + +++ + A ++ T+R R E + Y+FVS F+ I A
Sbjct 7 IVSAASGTGKSSIVNATLERDQ-QIALSISFTSRQPRPNERHAQHYYFVSADEFQRMIEA 65
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
G F E+ + GT+ SV + +G LL + Q + +RN IFI PPS+
Sbjct 66 GDFFEYALVHDDWKGTAHQSVEPQLAAGHDVLLEIDWQGARQVRNKIPDAISIFILPPSR 125
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQEL 655
L L K G++ + R + EM HY FD I+N + A E+
Sbjct 126 AALEERLRKRGQDSEEVIHRRLAAVHEEM----AHYDEFDYTIINEHFETAVSEM 176
>sp|O62683|ZO3_CANLF Tight junction protein ZO-3 OS=Canis lupus
familiaris OX=9615 GN=TJP3 PE=1 SV=1
Length=898
Score = 65.9 bits (159), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 92/455 (20%), Positives = 173/455 (38%), Gaps = 106/455 (23%)
Query 255 KIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
++VR K I L N++ + +S + +G A+ G+ EGD++L++N + R
Sbjct 371 RVVRFHKGTTIGLRLAGGNDV-GIFVSGVQEGSPADGQGI-QEGDQILQVNDVPFRNLTR 428
Query 315 NEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVI-------------HVKAHFDYDPSDD 361
E L L P ++++ + I +++ HF+ + S
Sbjct 429 EEAVQFL--------VALPPGEEVELVTQRNEDIFRKMVQSRVGDSFYIRTHFELEASPP 480
Query 362 PYVPCRELGLSFQKGDILHVISQEDPN---------WWQAYREGDEDNQPLAGLVPGKSF 412
GL F +GD+ HV+ P W A R G + + G++P +S
Sbjct 481 S-------GLGFTRGDVFHVLDTLCPGPGPSGARGTHWLAVRMGRDLREQERGIIPNQSR 533
Query 413 QQQREAMKQTIEE-DKEPEKS------GKLW-------CAKKNKKKRKKVLYNANKNDDY 458
+Q +++ P S + W AKK+ ++ ++ L + Y
Sbjct 534 AEQLASLESAQRAVGAGPGASVGSSARAEFWRLRGLRRGAKKSTQRSREDLSALTRQGHY 593
Query 459 DNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR 518
E + E S KRP++++GP + Q+L + D+F
Sbjct 594 PPYERVVLREASF-------KRPVVILGPV---ADIAMQKLTAEMPDQFG---------- 633
Query 519 RDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
++ D + K I+ +D+VR + K LL +
Sbjct 634 ------------IADSVLRTD-SPSKIIK------------LDTVRVIAEKNKHALLDVT 668
Query 579 TQSLKTLRNSDLKPYIIFIAPPSQERLRAL---LAKEGKNPKPEELREIIEKTREMEQNN 635
+++ L P ++F AP S+ L+AL LA + R + + +++ +++
Sbjct 669 PSAVERLNYVQYYPIVVFCAPESRAALKALRQWLAPASR----RSARRLYAQAQKLRKHS 724
Query 636 GHYFDTAI-VNSDLDKAYQELLRLINKLDTEPQWV 669
H F I + D YQEL ++ + T P W
Sbjct 725 EHLFTATIPLRGTSDTWYQELKAVVREQQTRPIWT 759
Score = 35.0 bits (79), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 21/80 (26%), Positives = 39/80 (49%), Gaps = 3/80 (4%)
Query 254 VKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
VK V + + G T+ ++ + I I G A ++ L EGD +L+ING+
Sbjct 185 VKSVLVRRTESEEFGVTLGSQ---IFIKHITDSGLAARNRGLQEGDLILQINGVSSENLS 241
Query 314 VNEVFDLLSDMHGTLTFVLI 333
+++ L+ G LT +++
Sbjct 242 LSDTRRLIEKSEGKLTLLVL 261
>sp|Q5HAK7|KGUA_EHRRW Guanylate kinase OS=Ehrlichia ruminantium
(strain Welgevonden) OX=254945 GN=gmk PE=3 SV=1
Length=209
Score = 62.4 bits (150), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 50/183 (27%), Positives = 89/183 (49%), Gaps = 10/183 (5%)
Query 478 RKRPIILI--GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+L+ P G+ + Q L+N+ + +V TTR R++EV G+DY FV+
Sbjct 6 KSRGIMLVMSSPSGGGKTTISQLLVNELQGEIIRSVSVTTREPRNEEVEGKDYFFVTEDE 65
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQ-SLKTLRNSDLKPYI 594
F + +E+ + N YG V IN+G L S+ Q + K +
Sbjct 66 FHHLCNTNQMLEYAKVFGNYYGIPRRFVMDNINNGISILFSIDWQGAFKLIDIMSEHVVS 125
Query 595 IFIAPPSQERL-RALLAKEGKNPK-PEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAY 652
+FI PPS E L R L + G++ + L+E E ++ + ++ IVN +++++
Sbjct 126 VFILPPSMEELKRRLYNRSGESDMINQRLKE-----AAFEISHCYRYNYIIVNHNIEESV 180
Query 653 QEL 655
Q++
Sbjct 181 QQI 183
>sp|Q5FFZ9|KGUA_EHRRG Guanylate kinase OS=Ehrlichia ruminantium
(strain Gardel) OX=302409 GN=gmk PE=3 SV=1
Length=209
Score = 62.4 bits (150), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 50/183 (27%), Positives = 89/183 (49%), Gaps = 10/183 (5%)
Query 478 RKRPIILI--GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+L+ P G+ + Q L+N+ + +V TTR R++EV G+DY FV+
Sbjct 6 KSRGIMLVMSSPSGGGKTTISQLLVNELQGEIIRSVSVTTREPRNEEVEGKDYFFVTEDE 65
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQ-SLKTLRNSDLKPYI 594
F + +E+ + N YG V IN+G L S+ Q + K +
Sbjct 66 FHHLCNTNQMLEYAKVFGNYYGIPRRFVMDNINNGISILFSIDWQGAFKLIDIMSEHVVS 125
Query 595 IFIAPPSQERL-RALLAKEGKNPK-PEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAY 652
+FI PPS E L R L + G++ + L+E E ++ + ++ IVN +++++
Sbjct 126 VFILPPSMEELKRRLYNRSGESDMINQRLKE-----AAFEISHCYRYNYIIVNHNIEESV 180
Query 653 QEL 655
Q++
Sbjct 181 QQI 183
>sp|Q2G9M5|KGUA_NOVAD Guanylate kinase OS=Novosphingobium aromaticivorans
(strain ATCC 700278 / DSM 12444 / CCUG 56034 / CIP
105152 / NBRC 16084 / F199) OX=279238 GN=gmk PE=3 SV=1
Length=221
Score = 62.4 bits (150), Expect = 1e-09, Method: Composition-based stats.
Identities = 42/134 (31%), Positives = 62/134 (46%), Gaps = 2/134 (1%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
IL P G+ + ++L++ E A +V TTR R EV G+DY FV FE + A
Sbjct 24 ILSSPSGAGKTTIARKLLS-EDSEIAMSVSVTTRPMRPGEVDGKDYFFVEPAEFERMVEA 82
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-IFIAPPS 601
+F E N YGT +R+ + +G L + Q + L + +FI PPS
Sbjct 83 NEFYEWATVFGNCYGTPKAHIRERLKTGGDVLFDIDWQGTQQLYQKAQADVVRVFILPPS 142
Query 602 QERLRALLAKEGKN 615
+ LR L G +
Sbjct 143 LDELRRRLTGRGTD 156
>sp|Q2GD44|KGUA_NEOSM Guanylate kinase OS=Neorickettsia sennetsu
(strain ATCC VR-367 / Miyayama) OX=222891 GN=gmk PE=3 SV=1
Length=206
Score = 62.0 bits (149), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 48/182 (26%), Positives = 83/182 (46%), Gaps = 10/182 (5%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+ P G+ + L+ ++ ++ TTR R +E G DY+FVS+ F +
Sbjct 7 FIISSPSGGGKTTVADFLVGQDLS-IKRSISFTTRQPRGEEKDGIDYYFVSKDEFNRLLQ 65
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+ +EH +N YGTS + + + G L + Q + +R IF+ PPS
Sbjct 66 EGEMLEHATVLQNQYGTSHRYIEETLALGIDVLCCIDWQGAEQIRKKT-NCISIFLLPPS 124
Query 602 QERLRALLAKEGKNPKPEELREIIE---KTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
++L+ L G + ++IE K E + +D +VN DL + Q++L +
Sbjct 125 LQKLKTRLTSRGTDTA-----DVIEYRLKVALEEIQHFSKYDYVLVNDDLTETKQKVLSI 179
Query 659 IN 660
I
Sbjct 180 IT 181
>sp|Q215S7|KGUA_RHOPB Guanylate kinase OS=Rhodopseudomonas palustris
(strain BisB18) OX=316056 GN=gmk PE=3 SV=1
Length=219
Score = 62.0 bits (149), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 48/178 (27%), Positives = 78/178 (44%), Gaps = 10/178 (6%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+L P G+ L RL+ + +V TTR++R E GRDY+FV F+A
Sbjct 18 FVLSSPSGAGKTTL-SRLLIERVAGLKMSVSATTRTKRPGEEDGRDYYFVDHARFQAMTE 76
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-IFIAPP 600
+ +E N YGT V + G+ L + Q + LR + +FI PP
Sbjct 77 NAELLEWANVFDNCYGTPRAPVEAALAVGQDVLFDIDWQGTQQLREKARDDVVSVFILPP 136
Query 601 SQERLRALLAKEGKNPKPEELREIIE-KTREMEQNNGHY--FDTAIVNSDLDKAYQEL 655
S L L + + ++ E+I + H+ +D +VN D+D+A+ E+
Sbjct 137 SAADLEKRL-----HTRAQDSDEVIRGRMSRASHELSHFAEYDYIVVNHDIDEAFAEV 189
>sp|Q95168|ZO2_CANLF Tight junction protein ZO-2 OS=Canis lupus
familiaris OX=9615 GN=TJP2 PE=1 SV=1
Length=1174
Score = 65.5 bits (158), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 102/447 (23%), Positives = 193/447 (43%), Gaps = 79/447 (18%)
Query 239 DERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEG 298
DE +Y G K+VR +K + L N++ + ++ I +G +AE+ GL EG
Sbjct 486 DEAIY-------GPNTKMVRFKKGDSVGLRLAGGNDV-GIFVAGIQEGTSAEQEGL-QEG 536
Query 299 DEVLEINGIEIRG-KDVNEVFDLLSDMHGTLTFVLIPSQ----QIKPPPAKETVIHVKAH 353
D++L++N + RG + V LL G + +L S+ + + +++H
Sbjct 537 DQILKVNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRADVYRDILACGRGDSFFIRSH 596
Query 354 FDYDPSDDPYVPCRELGLSFQKGDILHVIS---QEDPNWWQAYREGDEDNQPLAGLVPGK 410
F+ + + P L+F +G++ V+ W A R G+E + GL+P K
Sbjct 597 FECE-KETPQ------SLAFSRGEVFRVVDTLYDGKLGHWLAVRIGNELEK---GLIPNK 646
Query 411 SFQQQREAMKQTIEEDKEPEKS------GKLWCAKKNKKKRKKVLYNANKNDDYDNEEIL 464
S +Q ++ Q + D +++ G+ KKN +K ++ L A + +
Sbjct 647 SRAEQMASV-QNAQRDNAGDRADFWRMRGQRSGMKKNLRKSREDLTAAVSV----STKFP 701
Query 465 TYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVA 524
YE + L + A KRP++L GP + ++L N+ D F +A + + + A
Sbjct 702 AYERVLL--REAGFKRPVVLFGPI---ADIALEKLANELPDLFQTA-------KTEPKDA 749
Query 525 GRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKT 584
G EK+ +++VRQ+I K LL + +++
Sbjct 750 GS-------------------------EKSSGVVRLNTVRQIIEQDKHALLDVTPKAVDL 784
Query 585 LRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKP-EELREIIEKTREMEQNNGHYFDTAI 643
L + P +IF P S++ ++ + ++ NP + R++ ++ ++++ H F I
Sbjct 785 LNYTQWFPIVIFFNPDSRQGVKTM--RQRLNPTSNKSSRKLYDQANKLKKTCAHLFTATI 842
Query 644 -VNSDLDKAYQELLRLINKLDTEPQWV 669
+NS D + L I E WV
Sbjct 843 NLNSANDSWFGSLKDTIQHQQGEAVWV 869
Score = 37.4 bits (85), Expect = 0.50, Method: Compositional matrix adjust.
Identities = 22/80 (28%), Positives = 39/80 (49%), Gaps = 7/80 (9%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
+ I ++ + A K G LHEGD +L+ING + + L+ G L V++
Sbjct 311 IFIKQMTRTALATKDGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRD-- 368
Query 338 IKPPPAKETVIHVKAHFDYD 357
+K+T+I++ + D D
Sbjct 369 -----SKQTLINIPSLNDSD 383
>sp|Q9NPB6|PAR6A_HUMAN Partitioning defective 6 homolog alpha
OS=Homo sapiens OX=9606 GN=PARD6A PE=1 SV=1
Length=346
Score = 63.5 bits (153), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 37/99 (37%), Positives = 55/99 (56%), Gaps = 13/99 (13%)
Query 252 ETVKIVRIEK-ARDIPLGATVRNEMD------------SVIISRIVKGGAAEKSGLLHEG 298
ET + VR+ K D PLG +R+ M + ISR+V+GG AE +GLL
Sbjct 153 ETHRRVRLHKHGSDRPLGFYIRDGMSVRVAPQGLERVPGIFISRLVRGGLAESTGLLAVS 212
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
DE+LE+NGIE+ GK +++V D++ L + P+ Q
Sbjct 213 DEILEVNGIEVAGKTLDQVTDMMVANSHNLIVTVKPANQ 251
>sp|Q9UDY2|ZO2_HUMAN Tight junction protein ZO-2 OS=Homo sapiens
OX=9606 GN=TJP2 PE=1 SV=2
Length=1190
Score = 64.7 bits (156), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 101/447 (23%), Positives = 192/447 (43%), Gaps = 79/447 (18%)
Query 239 DERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEG 298
DE +Y G K+VR +K + L N++ + ++ I +G +AE+ GL EG
Sbjct 502 DEAIY-------GPNTKMVRFKKGDSVGLRLAGGNDV-GIFVAGIQEGTSAEQEGL-QEG 552
Query 299 DEVLEINGIEIRG-KDVNEVFDLLSDMHGTLTFVLIPSQ----QIKPPPAKETVIHVKAH 353
D++L++N + RG + V LL G + +L S+ + + +++H
Sbjct 553 DQILKVNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRADVYRDILACGRGDSFFIRSH 612
Query 354 FDYDPSDDPYVPCRELGLSFQKGDILHVIS---QEDPNWWQAYREGDEDNQPLAGLVPGK 410
F+ + + P L+F +G++ V+ W A R G+E + GL+P K
Sbjct 613 FECE-KETPQ------SLAFTRGEVFRVVDTLYDGKLGNWLAVRIGNELEK---GLIPNK 662
Query 411 SFQQQREAMKQTIEEDKEPEKS------GKLWCAKKNKKKRKKVLYNANKNDDYDNEEIL 464
S +Q ++ Q + D +++ G+ KKN +K ++ L + +
Sbjct 663 SRAEQMASV-QNAQRDNAGDRADFWRMRGQRSGVKKNLRKSREDLTAVVSV----STKFP 717
Query 465 TYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVA 524
YE + L + A KRP++L GP + ++L N+ D F +A + + + A
Sbjct 718 AYERVLL--REAGFKRPVVLFGPI---ADIAMEKLANELPDWFQTA-------KTEPKDA 765
Query 525 GRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKT 584
G EK+ +++VRQ+I K LL + +++
Sbjct 766 GS-------------------------EKSTGVVRLNTVRQIIEQDKHALLDVTPKAVDL 800
Query 585 LRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKP-EELREIIEKTREMEQNNGHYFDTAI 643
L + P +IF P S++ ++ + ++ NP + R++ ++ ++++ H F I
Sbjct 801 LNYTQWFPIVIFFNPDSRQGVKTM--RQRLNPTSNKSSRKLFDQANKLKKTCAHLFTATI 858
Query 644 -VNSDLDKAYQELLRLINKLDTEPQWV 669
+NS D + L I E WV
Sbjct 859 NLNSANDSWFGSLKDTIQHQQGEAVWV 885
Score = 38.5 bits (88), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 22/80 (28%), Positives = 38/80 (48%), Gaps = 7/80 (9%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
+ + + + G A K G LHEGD +L+ING + + L+ G L V++ Q
Sbjct 327 IFVKEMTRTGLATKDGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQ 386
Query 338 IKPPPAKETVIHVKAHFDYD 357
+T+I++ + D D
Sbjct 387 -------QTLINIPSLNDSD 399
>sp|Q6MU25|KGUA_MYCMS Guanylate kinase OS=Mycoplasma mycoides
subsp. mycoides SC (strain PG1) OX=272632 GN=gmk PE=3 SV=1
Length=297
Score = 62.8 bits (151), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 37/128 (29%), Positives = 56/128 (44%), Gaps = 0/128 (0%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ + II+ GP G+ + L+ +V TTR R+ EV G +Y FVS + F
Sbjct 3 KGKMIIISGPSGVGKGSVNGELLQNPDLHLRYSVSMTTRKPRNGEVDGVNYFFVSNEEFA 62
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I + IE+ F N YGT V Q + G +L + + N + IF+
Sbjct 63 KAIVNDELIEYAHFVGNSYGTPRKYVEQELKKGNNVILEIEVDGATQVLNKEPNVLSIFL 122
Query 598 APPSQERL 605
PP+ L
Sbjct 123 MPPNPTEL 130
>sp|Q6B4M5|PAR6A_RAT Partitioning defective 6 homolog alpha OS=Rattus
norvegicus OX=10116 GN=Pard6a PE=1 SV=2
Length=346
Score = 63.2 bits (152), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 37/99 (37%), Positives = 55/99 (56%), Gaps = 13/99 (13%)
Query 252 ETVKIVRIEK-ARDIPLGATVRNEMD------------SVIISRIVKGGAAEKSGLLHEG 298
ET + VR+ K D PLG +R+ M + ISR+V+GG AE +GLL
Sbjct 153 ETHRRVRLHKHGSDRPLGFYIRDGMSVRVAPQGLERVPGIFISRLVRGGLAESTGLLAVS 212
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
DE+LE+NGIE+ GK +++V D++ L + P+ Q
Sbjct 213 DEILEVNGIEVAGKTLDQVTDMMVANSHNLIVTVKPANQ 251
>sp|Q8XXF9|KGUA_RALN1 Guanylate kinase OS=Ralstonia nicotianae
(strain GMI1000) OX=267608 GN=gmk PE=3 SV=1
Length=221
Score = 61.2 bits (147), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 47/178 (26%), Positives = 80/178 (45%), Gaps = 3/178 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ P G++ L L+ ++ +V TTR R E GR+Y+F++ F+A
Sbjct 23 FMVVAPSGAGKSTLVNALLAQDPS-IRLSVSATTRKPRPGEQHGREYNFMTVDEFKACRD 81
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+F+E E N Y TS + + + +G LL + Q + + IFI PPS
Sbjct 82 RGEFLEWAEVHGNYYATSRVWIEEQMRAGTDVLLEIDWQGAQQVHRRFANAVEIFILPPS 141
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
L L K G++ +R ++ EM + D I+N + A EL ++
Sbjct 142 LTALEDRLKKRGQDEPNVIVRRLLAAGSEMA--HAPEADYVIINEVFEAALAELRTVV 197
>sp|Q8RHI9|KGUA_FUSNN Guanylate kinase OS=Fusobacterium nucleatum
subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681
/ CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)
OX=190304 GN=gmk PE=3 SV=1
Length=185
Score = 60.5 bits (145), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 44/177 (25%), Positives = 85/177 (48%), Gaps = 4/177 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
++ GP G++ + + + +E+ ++ T+R R+ E G DY F++ + FE I
Sbjct 8 VVSGPSGAGKSTVCK--LVRERLGINLSISATSRKPRNGEQEGVDYFFITAEEFERKIKN 65
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
F+E+ N YGT V + + G+ LL + Q ++N + +IF ++
Sbjct 66 DDFLEYANVHGNYYGTLKSEVEERLKRGEKVLLEIDVQGGVQVKNKFPEANLIFFKTANK 125
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
E L L G+N EE+ + K E +D I+N+++++A +L+ +I
Sbjct 126 EELEKRL--RGRNTDSEEVIQARLKNSLKELEYESKYDRVIINNEIEQACNDLISII 180
>sp|Q9Z101|PAR6A_MOUSE Partitioning defective 6 homolog alpha
OS=Mus musculus OX=10090 GN=Pard6a PE=1 SV=2
Length=346
Score = 62.8 bits (151), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 37/99 (37%), Positives = 55/99 (56%), Gaps = 13/99 (13%)
Query 252 ETVKIVRIEK-ARDIPLGATVRNEMD------------SVIISRIVKGGAAEKSGLLHEG 298
ET + VR+ K D PLG +R+ M + ISR+V+GG AE +GLL
Sbjct 153 ETHRRVRLHKHGSDRPLGFYIRDGMSVRVAPQGLERVPGIFISRLVRGGLAESTGLLAVS 212
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
DE+LE+NGIE+ GK +++V D++ L + P+ Q
Sbjct 213 DEILEVNGIEVAGKTLDQVTDMMVANSHNLIVTVKPANQ 251
>sp|Q9Z0U1|ZO2_MOUSE Tight junction protein ZO-2 OS=Mus musculus
OX=10090 GN=Tjp2 PE=1 SV=2
Length=1167
Score = 63.9 bits (154), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 98/449 (22%), Positives = 185/449 (41%), Gaps = 81/449 (18%)
Query 239 DERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEG 298
DE +Y G K+VR +K + L N++ + ++ I +G +AE+ GL EG
Sbjct 482 DEAIY-------GPNTKMVRFKKGDSVGLRLAGGNDV-GIFVAGIQEGTSAEQEGL-QEG 532
Query 299 DEVLEINGIEIRG-KDVNEVFDLLSDMHGTLTFVLIPSQ----QIKPPPAKETVIHVKAH 353
D++L++N + RG + V LL G +L S+ + + +++H
Sbjct 533 DQILKVNTQDFRGLVREDAVLYLLEIPKGETVTILAQSRADVYRDILACGRGDSFFIRSH 592
Query 354 FDYDPSDDPYVPCRELGLSFQKGDILHVIS---QEDPNWWQAYREGDEDNQPLAGLVPGK 410
F+ + + P L+F +G++ V+ W A R G+E + GL+P K
Sbjct 593 FECE-KETPQ------SLAFTRGEVFRVVDTLYDGKLGHWLAVRIGNELEK---GLIPNK 642
Query 411 SFQQQREAMKQTIEEDKEPEKSGKLW---------CAKKNKKKRKKVLYNANKNDDYDNE 461
S +Q +++ E+ W KKN +K ++ L A +
Sbjct 643 SRAEQMASVQNAQRENA--GDRADFWRMRGQRSSGGVKKNLRKSREDLAAAVSV----ST 696
Query 462 EILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQ 521
+ YE++ L + A KRP++L GP + + +R A+ +P
Sbjct 697 KFPAYEKVLL--REAGFKRPVVLFGP-----------IADIAMERLATELPDL------- 736
Query 522 EVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS 581
F + + D + EK+ +++VRQ+I K LL + ++
Sbjct 737 --------FQTAKTEPKDAGS---------EKSSGVVRLNTVRQIIEQDKHALLDVTPKA 779
Query 582 LKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDT 641
+ L + P +IF P S++ ++ + + + R++ ++ ++++ H F
Sbjct 780 VDLLNYTQWFPIVIFFNPDSRQGVKTIRQRLSPTSN-KSSRKLFDQANKLKKTCSHLFTA 838
Query 642 AI-VNSDLDKAYQELLRLINKLDTEPQWV 669
I VNS D + L I + E WV
Sbjct 839 TINVNSANDGWFGSLKDSIQQQQNEAVWV 867
Score = 40.4 bits (93), Expect = 0.066, Method: Compositional matrix adjust.
Identities = 24/80 (30%), Positives = 39/80 (49%), Gaps = 7/80 (9%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
+ I + + G A K G LHEGD +L+ING + + L+ G L V++
Sbjct 307 IFIKEMTRTGLATKDGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRD-- 364
Query 338 IKPPPAKETVIHVKAHFDYD 357
+K+T+I++ A D D
Sbjct 365 -----SKQTLINIPALNDSD 379
>sp|Q3YRE2|KGUA_EHRCJ Guanylate kinase OS=Ehrlichia canis (strain
Jake) OX=269484 GN=gmk PE=3 SV=1
Length=209
Score = 60.8 bits (146), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 47/180 (26%), Positives = 87/180 (48%), Gaps = 14/180 (8%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ P G+ + L+++ ++ +V TTR RD EV G+DY FV+ F
Sbjct 12 LVISSPSGGGKTTISHLLIDELQNDLVRSVSVTTREPRDGEVNGKDYFFVTEHEFINLCN 71
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI--IFIAP 599
+ +E+ + N YG V I +G L S+ Q L + ++ ++ +FI P
Sbjct 72 TDQMLEYAKVFGNYYGIPRKFVMDNITTGVSVLFSIDWQGAFKLIDI-MREHVVSVFILP 130
Query 600 PSQERL-RALLAKEGKNPKPEELREIIEKT---REMEQNNGHYFDTAIVNSDLDKAYQEL 655
PS E L R L + GK+ +I++K E ++ + +D IVN D++++ ++
Sbjct 131 PSMEELRRRLYNRSGKS-------DIVKKRLGEAAFEIDHCYRYDYVIVNHDVEESVHQI 183
>sp|Q4A8L2|KGUA_MESH7 Guanylate kinase OS=Mesomycoplasma hyopneumoniae
(strain 7448) OX=262722 GN=gmk PE=3 SV=1
Length=197
Score = 60.5 bits (145), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 51/188 (27%), Positives = 88/188 (47%), Gaps = 8/188 (4%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
+ IIL GP G+ + L+ + A+ TTR +R E+ G +Y F++ Q F+
Sbjct 7 KLIILSGPSGVGKGTIESLLLKNKNLLIKLAISATTREKRRDEINGVNYFFLTVQEFKEK 66
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTL-----RNSDLKPYI 594
I +FIE N YGT ++ + + I LL + T K + +L +
Sbjct 67 IENDEFIEWSCHFNNYYGTLKSQIKFIQSQNFIPLLEIDTTGAKNIIENYKNKGELSQLL 126
Query 595 -IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI PPS E L+ + K ++ + +EK + E + F +VN +L+K
Sbjct 127 TIFILPPSIESLKNRIQKRLTETNI-QINQRLEKAK-AEIKVKNLFKFQVVNDNLEKCVA 184
Query 654 ELLRLINK 661
++ ++I+K
Sbjct 185 QIEKIISK 192
>sp|Q0BPZ9|KGUA_GRABC Guanylate kinase OS=Granulibacter bethesdensis
(strain ATCC BAA-1260 / CGDNIH1) OX=391165 GN=gmk PE=3
SV=1
Length=213
Score = 60.1 bits (144), Expect = 6e-09, Method: Composition-based stats.
Identities = 52/204 (25%), Positives = 97/204 (48%), Gaps = 9/204 (4%)
Query 475 PANRKRPIILI--GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVS 532
P +R + L+ P G++ + + L+ E +V TTR+ R E G Y+F +
Sbjct 6 PETGRRGLCLVVAAPSGAGKSSITRALL-AEDPGLRLSVSVTTRAPRAGEQEGVHYYFRT 64
Query 533 RQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKP 592
++ F+A A G+ +E+ YGT V++ ++ G L + Q LR++
Sbjct 65 QEEFDAMAAEGQLLEYARVFGRSYGTPRGPVQKALSEGSDVLFDVDWQGYHQLRSALPGD 124
Query 593 YI-IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
+ IF+ PPS + L + L EG+ P+ + + + R+ + G F +VN+ L +A
Sbjct 125 VVGIFVLPPSLDDLASRL--EGRGDAPDIIAQRMAAARDEIAHVGE-FPYVVVNTHLPEA 181
Query 652 YQELLRLINKLDTEPQWVPSTWLR 675
++ +++ TE + WLR
Sbjct 182 IDQVRTILHAARTETK--RQGWLR 203
>sp|Q5FS85|KGUA_GLUOX Guanylate kinase OS=Gluconobacter oxydans
(strain 621H) OX=290633 GN=gmk PE=3 SV=1
Length=208
Score = 59.7 bits (143), Expect = 7e-09, Method: Composition-based stats.
Identities = 50/174 (29%), Positives = 79/174 (45%), Gaps = 4/174 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ P G++ + L E +V TTRS R EV G YHF F A
Sbjct 11 LVISAPSGAGKSTIANALRASEPT-LRHSVSVTTRSPRPGEVEGVHYHFRDIAEFRRMAA 69
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-IFIAPP 600
G+ +E E YGT V + +++G + + Q + LR + + +F+ PP
Sbjct 70 DGELLEWAEVFGRGYGTPRAPVEEALDAGHDMVFDIDWQGHRLLRAALPDDVVSLFVLPP 129
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
S E L L K + PEE+ ++ + E ++ FD I+NSDLD A +
Sbjct 130 SLEELERRLNKRASD-HPEEIARRMKAALD-EISHWSEFDHTIINSDLDTAISQ 181
>sp|Q87DG5|KGUA_XYLFT Guanylate kinase OS=Xylella fastidiosa (strain
Temecula1 / ATCC 700964) OX=183190 GN=gmk PE=3 SV=1
Length=204
Score = 58.9 bits (141), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 46/176 (26%), Positives = 80/176 (45%), Gaps = 9/176 (5%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I+ G++ + + +++ + A ++ T+R R E + Y+FVS F+ I A
Sbjct 7 IVSASSGTGKSSIVNATLERDQ-QIALSISFTSRQPRPNERHAQHYYFVSADEFQRMIEA 65
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
G F E+ + GT+ SV + +G LL + Q + +R+ IFI PPS+
Sbjct 66 GDFFEYALVHGDWKGTARQSVEPQLAAGHDVLLEIDWQGARQVRSKIPDAISIFILPPSR 125
Query 603 ERLRALLAKEGKNPKPEELREIIE-KTREMEQNNGHY--FDTAIVNSDLDKAYQEL 655
L L K G++ + E+I + + HY FD I+N + A E+
Sbjct 126 AALEERLRKRGQDSE-----EVIHLRLAAAHEEMAHYDEFDYTIINEHFETAVSEM 176
>sp|Q2GHE0|KGUA_EHRCR Guanylate kinase OS=Ehrlichia chaffeensis
(strain ATCC CRL-10679 / Arkansas) OX=205920 GN=gmk PE=3 SV=1
Length=209
Score = 58.9 bits (141), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 49/186 (26%), Positives = 89/186 (48%), Gaps = 16/186 (9%)
Query 478 RKRPIILI--GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+L+ P G+ + L+N+ ++ ++ TTR RD E+ G+DY FV+
Sbjct 6 KSRGIMLVISSPSGGGKTTISHLLINELQNDLVRSISVTTREPRDGEINGKDYFFVTEPE 65
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI- 594
F + +E+ + N YG V I +G L S+ Q L + ++ ++
Sbjct 66 FINLCNTNQMLEYAKVFGNYYGIPRKFVTDNIANGVSVLFSIDWQGAFKLIDI-MREHVV 124
Query 595 -IFIAPPSQERL-RALLAKEGKNPKPEELREIIEKT---REMEQNNGHYFDTAIVNSDLD 649
IFI PPS E L R L + G++ ++I K E ++ + +D IVN D++
Sbjct 125 SIFILPPSMEELQRRLYNRSGES-------DVINKRLGEAAFEISHCYRYDYVIVNHDIE 177
Query 650 KAYQEL 655
++ ++
Sbjct 178 QSVYQI 183
>sp|Q63RV7|KGUA_BURPS Guanylate kinase OS=Burkholderia pseudomallei
(strain K96243) OX=272560 GN=gmk PE=3 SV=1
Length=227
Score = 59.3 bits (142), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 44/174 (25%), Positives = 77/174 (44%), Gaps = 3/174 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ P G++ L L++K+ + ++ +TTR R E G+ YHF + + F A
Sbjct 24 FMVVAPSGAGKSTLVNALLSKDPE-IRLSISYTTRKPRPGEQDGQHYHFTTVEDFRERHA 82
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+F+E E N YGTS + + + G LL + Q + ++ IFI PPS
Sbjct 83 RHEFLESAEVHGNYYGTSRVWIEEQMKIGHDVLLEIDWQGAQQVKKQFRNAVGIFILPPS 142
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
L L K G++ R ++ E+ + ++N + A EL
Sbjct 143 LAALEERLKKRGQDEPNVITRRLLAAGSEIAHAAEAQY--VVINETFEHALAEL 194
>sp|Q3JPS9|KGUA_BURP1 Guanylate kinase OS=Burkholderia pseudomallei
(strain 1710b) OX=320372 GN=gmk PE=3 SV=1
Length=227
Score = 59.3 bits (142), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 44/174 (25%), Positives = 77/174 (44%), Gaps = 3/174 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ P G++ L L++K+ + ++ +TTR R E G+ YHF + + F A
Sbjct 24 FMVVAPSGAGKSTLVNALLSKDPE-IRLSISYTTRKPRPGEQDGQHYHFTTVEDFRERHA 82
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+F+E E N YGTS + + + G LL + Q + ++ IFI PPS
Sbjct 83 RHEFLESAEVHGNYYGTSRVWIEEQMKIGHDVLLEIDWQGAQQVKKQFRNAVGIFILPPS 142
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
L L K G++ R ++ E+ + ++N + A EL
Sbjct 143 LAALEERLKKRGQDEPNVITRRLLAAGSEIAHAAEAQY--VVINETFEHALAEL 194
>sp|Q62I00|KGUA_BURMA Guanylate kinase OS=Burkholderia mallei
(strain ATCC 23344) OX=243160 GN=gmk PE=3 SV=1
Length=227
Score = 59.3 bits (142), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 44/174 (25%), Positives = 77/174 (44%), Gaps = 3/174 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ P G++ L L++K+ + ++ +TTR R E G+ YHF + + F A
Sbjct 24 FMVVAPSGAGKSTLVNALLSKDPE-IRLSISYTTRKPRPGEQDGQHYHFTTVEDFRERHA 82
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+F+E E N YGTS + + + G LL + Q + ++ IFI PPS
Sbjct 83 RHEFLESAEVHGNYYGTSRVWIEEQMKIGHDVLLEIDWQGAQQVKKQFRNAVGIFILPPS 142
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
L L K G++ R ++ E+ + ++N + A EL
Sbjct 143 LAALEERLKKRGQDEPNVITRRLLAAGSEIAHAAEAQY--VVINETFEHALAEL 194
>sp|Q4AAI1|KGUA_MESHJ Guanylate kinase OS=Mesomycoplasma hyopneumoniae
(strain J / ATCC 25934 / NCTC 10110) OX=262719 GN=gmk
PE=3 SV=1
Length=197
Score = 58.5 bits (140), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 50/188 (27%), Positives = 88/188 (47%), Gaps = 8/188 (4%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
+ IIL GP G+ + L+ + A+ TTR +R E+ G +Y F++ Q F+
Sbjct 7 KLIILSGPSGVGKGTIESLLLKNKNLLIKLAISATTREKRRDEINGVNYFFLTVQEFKEK 66
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTL-----RNSDLKPYI 594
I +FIE N YGT ++ + + I LL + T K + +L +
Sbjct 67 IENDEFIEWSCHFNNYYGTLKSQIKFIQSQNFIPLLEIDTTGAKNIIENYKNKGELSQLL 126
Query 595 -IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI PPS E L+ + K ++ + +EK + E + F +VN +L++
Sbjct 127 TIFILPPSIESLKNRIQKRLTETNI-QINQRLEKAK-AEIKIKNLFKFQVVNDNLEECVA 184
Query 654 ELLRLINK 661
++ ++I+K
Sbjct 185 QIEKIISK 192
>sp|Q601H3|KGUA_MESH2 Guanylate kinase OS=Mesomycoplasma hyopneumoniae
(strain 232) OX=295358 GN=gmk PE=3 SV=1
Length=197
Score = 58.5 bits (140), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 50/188 (27%), Positives = 88/188 (47%), Gaps = 8/188 (4%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
+ IIL GP G+ + L+ + A+ TTR +R E+ G +Y F++ Q F+
Sbjct 7 KLIILSGPSGVGKGTIESLLLKNKNLLIKLAISATTREKRRDEINGVNYFFLTVQEFKEK 66
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTL-----RNSDLKPYI 594
I +FIE N YGT ++ + + I LL + T K + +L +
Sbjct 67 IENDEFIEWSCHFNNYYGTLKSQIKFIQSQNFIPLLEIDTTGAKNIIENYKNKGELSQLL 126
Query 595 -IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI PPS E L+ + K ++ + +EK + E + F +VN +L++
Sbjct 127 TIFILPPSIESLKNRIQKRLTETNI-QINQRLEKAK-AEIKIKNLFKFQVVNDNLEECVA 184
Query 654 ELLRLINK 661
++ ++I+K
Sbjct 185 QIEKIISK 192
>sp|Q6A8H6|KGUA_CUTAK Guanylate kinase OS=Cutibacterium acnes
(strain DSM 16379 / KPA171202) OX=267747 GN=gmk PE=3 SV=1
Length=199
Score = 57.4 bits (137), Expect = 4e-08, Method: Composition-based stats.
Identities = 42/148 (28%), Positives = 70/148 (47%), Gaps = 3/148 (2%)
Query 514 TTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKN-LYGTSIDSVRQVINSGKI 572
TTR R E G DY F++ + F+ + +E + YGT V + + +
Sbjct 53 TTRPPRPTERDGIDYDFITPEQFDKLVDGEGLLEWATVHNSHRYGTPRGPVERAVADNRT 112
Query 573 CLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREME 632
+L + Q + +R + + IF+APPS E L L G PE+ ++ +E T ++E
Sbjct 113 VVLEIDLQGARQVRETYPQATQIFLAPPSWEELVHRLIGRGTE-TPEQQKQRLE-TAKVE 170
Query 633 QNNGHYFDTAIVNSDLDKAYQELLRLIN 660
N FD +VN +D A L+ L++
Sbjct 171 LANADEFDAVVVNDTVDHAVAHLVELLS 198
>sp|Q9NAN2|PAR6_CAEEL Partitioning defective protein 6 OS=Caenorhabditis
elegans OX=6239 GN=par-6 PE=1 SV=2
Length=309
Score = 57.8 bits (138), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 55/99 (56%), Gaps = 13/99 (13%)
Query 252 ETVKIVRIEK-ARDIPLGATVRN------------EMDSVIISRIVKGGAAEKSGLLHEG 298
E + VR+ K ++ PLG +R+ ++ + ISR+V GG AE +GLL
Sbjct 152 EAHRRVRLCKHGQERPLGFYIRDGTSVRVTERGVVKVSGIFISRLVDGGLAESTGLLGVN 211
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
DEVLE+NGIE+ GK +++V D++ L + P+ Q
Sbjct 212 DEVLEVNGIEVLGKTLDQVTDMMVANAHNLIITVKPANQ 250
>sp|Q10M74|GMK2_ORYSJ Guanylate kinase 2, chloroplastic/mitochondrial
OS=Oryza sativa subsp. japonica OX=39947 GN=V2 PE=1
SV=1
Length=285
Score = 57.0 bits (136), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 50/186 (27%), Positives = 89/186 (48%), Gaps = 8/186 (4%)
Query 480 RPIILI--GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+P+IL+ GP G++ + QRL +E++ V T+R++R EV G+DY+FV+++ F
Sbjct 90 QPMILVISGPSGVGKDAVIQRL-QEEREGMHFVVTATSRAKRPGEVDGKDYYFVTKEEFL 148
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-IF 596
I + +E+ G +R + G +L + Q TLR + I IF
Sbjct 149 TMIERKELLEYALVYGEYKGIPKQQIRDYMAKGYDIVLRVDIQGAATLREILGESAIFIF 208
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNS--DLDKAYQE 654
+ S+E L L L + E+++ N FD +VNS +L+ A ++
Sbjct 209 LVAESEEALVKRLIHRKTETSDMLLVRVATAREEVKRMNN--FDYVVVNSEGNLEGAVKQ 266
Query 655 LLRLIN 660
+ +I+
Sbjct 267 VESIID 272
>sp|Q9JK83|PAR6B_MOUSE Partitioning defective 6 homolog beta OS=Mus
musculus OX=10090 GN=Pard6b PE=1 SV=2
Length=371
Score = 57.4 bits (137), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 55/99 (56%), Gaps = 13/99 (13%)
Query 252 ETVKIVRIEK-ARDIPLGATVRN------------EMDSVIISRIVKGGAAEKSGLLHEG 298
ET + VR+ K + PLG +R+ ++ + ISR+V GG A+ +GLL
Sbjct 153 ETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVN 212
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
DEVLE+NGIE+ GK +++V D++ L + P+ Q
Sbjct 213 DEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQ 251
>sp|Q9BYG5|PAR6B_HUMAN Partitioning defective 6 homolog beta OS=Homo
sapiens OX=9606 GN=PARD6B PE=1 SV=1
Length=372
Score = 57.4 bits (137), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 55/99 (56%), Gaps = 13/99 (13%)
Query 252 ETVKIVRIEK-ARDIPLGATVRN------------EMDSVIISRIVKGGAAEKSGLLHEG 298
ET + VR+ K + PLG +R+ ++ + ISR+V GG A+ +GLL
Sbjct 153 ETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVN 212
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
DEVLE+NGIE+ GK +++V D++ L + P+ Q
Sbjct 213 DEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQ 251
>sp|Q11XI0|KGUA_CYTH3 Guanylate kinase OS=Cytophaga hutchinsonii
(strain ATCC 33406 / DSM 1761 / CIP 103989 / NBRC 15051 /
NCIMB 9469 / D465) OX=269798 GN=gmk PE=3 SV=1
Length=192
Score = 55.1 bits (131), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 49/185 (26%), Positives = 89/185 (48%), Gaps = 8/185 (4%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRD-QEVAGRDYHFVSRQAFEADI 540
I P G+ + Q L+N + R ++ TR R+ +E G+DY+F+S FE I
Sbjct 6 FIFSAPSGSGKTTVVQHLLNTDP-RIGFSISACTREMRESKEANGKDYYFLSVDEFERRI 64
Query 541 AAGKFIEHGE-FEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS-DLKPYIIFIA 598
+F+E E + YGT V+++ + GK + + + +L+ K +F+
Sbjct 65 QNNEFVEWEEVYPGRYYGTLRSEVQRIWDMGKHVIFDVDVKGGLSLKEQFGDKALSVFVK 124
Query 599 PPSQERLRALLAKEGKNPKPEE-LREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PS E L+ L +N + E+ L+ +EK + E + FD +VN L++ + + +
Sbjct 125 VPSIEELQKRLID--RNTESEDSLKARLEKMK-YESSFQDQFDVILVNDRLEETFVKAHQ 181
Query 658 LINKL 662
LI+
Sbjct 182 LIDHF 186
>sp|Q64PY1|KGUA_BACFR Guanylate kinase OS=Bacteroides fragilis
(strain YCH46) OX=295405 GN=gmk PE=3 SV=1
Length=204
Score = 55.1 bits (131), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 54/194 (28%), Positives = 87/194 (45%), Gaps = 18/194 (9%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
II P G++ + L+ +K A ++ T+R R E G +Y F+S F IA
Sbjct 19 IIFSAPSGSGKSTIINYLL-AQKLNLAFSISATSRPPRGNEKHGVEYFFLSPDEFRQRIA 77
Query 542 AGKFIEHGE-FEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI------ 594
+F+E+ E + YGT V + + +G+ + + ++K Y
Sbjct 78 NNEFLEYEEVYTDRFYGTLKAQVEKQLAAGQ-----NVVFDVDVVGGCNIKKYYGERALS 132
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
+FI PP + LR L G + PE + I K E E + FD I+N DL+ A
Sbjct 133 LFIQPPCIDELRRRLIGRGTD-TPEVIESRIAKA-EYELSFAPKFDKVIINDDLETAKAH 190
Query 655 LLRLINK---LDTE 665
L++I + +DTE
Sbjct 191 ALKVIKEFLGIDTE 204
>sp|Q5L9N9|KGUA_BACFN Guanylate kinase OS=Bacteroides fragilis
(strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC
9343 / Onslow) OX=272559 GN=gmk PE=3 SV=1
Length=204
Score = 55.1 bits (131), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 54/194 (28%), Positives = 87/194 (45%), Gaps = 18/194 (9%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
II P G++ + L+ +K A ++ T+R R E G +Y F+S F IA
Sbjct 19 IIFSAPSGSGKSTIINYLL-AQKLNLAFSISATSRPPRGNEKHGVEYFFLSPDEFRQRIA 77
Query 542 AGKFIEHGE-FEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI------ 594
+F+E+ E + YGT V + + +G+ + + ++K Y
Sbjct 78 NNEFLEYEEVYTDRFYGTLKAQVEKQLAAGQ-----NVVFDVDVVGGCNIKKYYGERALS 132
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
+FI PP + LR L G + PE + I K E E + FD I+N DL+ A
Sbjct 133 LFIQPPCIDELRRRLIGRGTD-TPEVIESRIAKA-EYELSFAPKFDKVIINDDLETAKAH 190
Query 655 LLRLINK---LDTE 665
L++I + +DTE
Sbjct 191 ALKVIKEFLGIDTE 204
>sp|Q9BYG4|PAR6G_HUMAN Partitioning defective 6 homolog gamma
OS=Homo sapiens OX=9606 GN=PARD6G PE=1 SV=1
Length=376
Score = 56.6 bits (135), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 31/76 (41%), Positives = 46/76 (61%), Gaps = 6/76 (8%)
Query 268 GATVR------NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
GA+VR ++ + ISR+V GG AE +GLL DEVLE+NGIE+ GK +++V D++
Sbjct 177 GASVRVTPHGLEKVPGIFISRMVPGGLAESTGLLAVNDEVLEVNGIEVAGKTLDQVTDMM 236
Query 322 SDMHGTLTFVLIPSQQ 337
L + P+ Q
Sbjct 237 IANSHNLIVTVKPANQ 252
>sp|Q9JK84|PAR6G_MOUSE Partitioning defective 6 homolog gamma
OS=Mus musculus OX=10090 GN=Pard6g PE=2 SV=1
Length=382
Score = 56.6 bits (135), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 35/99 (35%), Positives = 55/99 (56%), Gaps = 13/99 (13%)
Query 252 ETVKIVRIEK-ARDIPLGATVRN------------EMDSVIISRIVKGGAAEKSGLLHEG 298
ET + VR+ + + PLG +R+ ++ + ISR+V GG AE +GLL
Sbjct 154 ETHRRVRLYRHGYEKPLGFYIRDGTSVRVTPHGLEKVPGIFISRMVPGGLAESTGLLAVN 213
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
DEVLE+NGIE+ GK +++V D++ L + P+ Q
Sbjct 214 DEVLEVNGIEVAGKTLDQVTDMMIANSHNLIVTVKPANQ 252
>sp|Q2RXB1|KGUA_RHORT Guanylate kinase OS=Rhodospirillum rubrum
(strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB
8255 / S1) OX=269796 GN=gmk PE=3 SV=1
Length=218
Score = 54.3 bits (129), Expect = 7e-07, Method: Composition-based stats.
Identities = 50/183 (27%), Positives = 76/183 (42%), Gaps = 12/183 (7%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R ++L P G+ + + L+ E+D +V TTR+ R E G YHF+ +
Sbjct 14 RGMMLVLSSPSGAGKTTISRALL-AEEDGLEMSVSVTTRAPRPGERDGEHYHFIDVARYM 72
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR---TQSLKTLRNSDLKPYI 594
A +EH +N YGT V + G L + TQ + +DL
Sbjct 73 ALTKDDGLLEHARVFENYYGTPRAPVEAALARGCDVLFDIDWQGTQQVAEKARTDLVS-- 130
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYF--DTAIVNSDLDKAY 652
IFI PPS L L ++ + + E+ HYF D IVN DLD++
Sbjct 131 IFILPPSVGELERRLKGRAQDSDAVVAARMAKAMDEIS----HYFEYDYIIVNDDLDRSI 186
Query 653 QEL 655
++
Sbjct 187 ADV 189
>sp|Q3ZAF9|KGUA_DEHM1 Guanylate kinase OS=Dehalococcoides mccartyi
(strain ATCC BAA-2266 / KCTC 15142 / 195) OX=243164 GN=gmk
PE=3 SV=1
Length=206
Score = 52.8 bits (125), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 48/187 (26%), Positives = 86/187 (46%), Gaps = 5/187 (3%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
AN+ +++ GP G++ + R M + K A V TTR++R++E G DY+F+
Sbjct 10 ANKPLLLVVSGPSGVGKDAVLAR-MKERKLPLAYIVTTTTRTKREKETEGVDYNFIRPAE 68
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F+ I + +E N YG +RQ + G ++ + Q +++ I
Sbjct 69 FQQLIGQNELLEWANVYGNFYGVPKAPIRQALAHGFDVIVKVDVQGAASIKKIVPNAVFI 128
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVN--SDLDKAYQ 653
F+ PP + L L + PE L+ + T +E FD +VN ++D A
Sbjct 129 FLMPPDMDELTRRL-EHRLTESPESLKRRL-ATAPLEIEKLPDFDYVVVNPEGEIDNAVS 186
Query 654 ELLRLIN 660
E++ +I+
Sbjct 187 EIMSIIS 193
>sp|Q6KH87|KGUA_MESM1 Guanylate kinase OS=Mesomycoplasma mobile
(strain ATCC 43663 / 163K / NCTC 11711) OX=267748 GN=gmk PE=3
SV=1
Length=201
Score = 52.4 bits (124), Expect = 2e-06, Method: Composition-based stats.
Identities = 44/144 (31%), Positives = 64/144 (44%), Gaps = 6/144 (4%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
IIL GP G+ + + L+ EK + + T+R R E+ G+DY F S + F I
Sbjct 13 IILSGPSGVGKGSIEKLLLEDEKLKLKFSTSVTSRKPRVNEIEGKDYFFRSEEEFSELIK 72
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQ-SLKTLRNSDLKPYI-----I 595
KFIE N YGT V +++ + L+ + T +L L+ K + I
Sbjct 73 EKKFIEWSRHLNNYYGTLKSEVDKILGAKFNVLIEIETTGALNILKYYKKKNMLNDVISI 132
Query 596 FIAPPSQERLRALLAKEGKNPKPE 619
FI PP E L + G K E
Sbjct 133 FILPPRLEELETRILNRGSETKEE 156
>sp|P97879|GRIP1_RAT Glutamate receptor-interacting protein 1
OS=Rattus norvegicus OX=10116 GN=Grip1 PE=1 SV=1
Length=1112
Score = 53.5 bits (127), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 27/68 (40%), Positives = 39/68 (57%), Gaps = 3/68 (4%)
Query 266 PLGATVRNE---MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
PLG T+ D +IIS + KGG AE++G +H GD +L IN ++GK ++E LL
Sbjct 681 PLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQ 740
Query 323 DMHGTLTF 330
T+T
Sbjct 741 MAGETVTL 748
Score = 40.0 bits (92), Expect = 0.075, Method: Compositional matrix adjust.
Identities = 32/133 (24%), Positives = 56/133 (42%), Gaps = 8/133 (6%)
Query 211 LLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGAT 270
LL T H +A+ + K QE L D V +S+ G +V + K LG
Sbjct 211 LLGTTHAEAMSIL--KQCGQEATLLIEYDVSVMDSVATASGPL--LVEVAKTPGASLGVA 266
Query 271 VRNEMDS----VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
+ + ++I +I A++ G LH GD +L I+G + + E L++
Sbjct 267 LTTSVCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTSMEYCTLAEATQFLANTTD 326
Query 327 TLTFVLIPSQQIK 339
+ ++P Q +
Sbjct 327 QVKLEILPHHQTR 339
Score = 36.2 bits (82), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 16/50 (32%), Positives = 28/50 (56%), Gaps = 0/50 (0%)
Query 272 RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
RN+ V+I+ + GG A++ G + GD +L ++GI + G E +L
Sbjct 174 RNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSIL 223
Score = 36.2 bits (82), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query 257 VRIEKARDIPLGATV-----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
V++ K + LG T+ R D ++IS I KG A ++G L GD++L I+ I +
Sbjct 573 VKLPKKHSVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDS 632
Query 312 KDVNEVFDLL 321
+ + +L
Sbjct 633 CSMEDAVQIL 642
>sp|Q925T6|GRIP1_MOUSE Glutamate receptor-interacting protein
1 OS=Mus musculus OX=10090 GN=Grip1 PE=1 SV=1
Length=1127
Score = 53.5 bits (127), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 27/68 (40%), Positives = 39/68 (57%), Gaps = 3/68 (4%)
Query 266 PLGATVRNE---MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
PLG T+ D +IIS + KGG AE++G +H GD +L IN ++GK ++E LL
Sbjct 681 PLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQ 740
Query 323 DMHGTLTF 330
T+T
Sbjct 741 MAGETVTL 748
Score = 40.4 bits (93), Expect = 0.070, Method: Compositional matrix adjust.
Identities = 32/133 (24%), Positives = 56/133 (42%), Gaps = 8/133 (6%)
Query 211 LLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGAT 270
LL T H +A+ + K QE L D V +S+ G +V + K LG
Sbjct 211 LLGTTHAEAMSIL--KQCGQEATLLIEYDVSVMDSVATASGPL--LVEVAKTPGASLGVA 266
Query 271 VRNEMDS----VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
+ + ++I +I A++ G LH GD +L I+G + + E L++
Sbjct 267 LTTSVCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTSMEYCTLAEATQFLANTTD 326
Query 327 TLTFVLIPSQQIK 339
+ ++P Q +
Sbjct 327 QVKLEILPHHQTR 339
Score = 36.6 bits (83), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 16/50 (32%), Positives = 28/50 (56%), Gaps = 0/50 (0%)
Query 272 RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
RN+ V+I+ + GG A++ G + GD +L ++GI + G E +L
Sbjct 174 RNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSIL 223
Score = 35.8 bits (81), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query 257 VRIEKARDIPLGATV-----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
V++ K + LG T+ R D ++IS I KG A ++G L GD++L I+ I +
Sbjct 573 VKLPKKHSVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDN 632
Query 312 KDVNEVFDLL 321
+ + +L
Sbjct 633 CSMEDAVQIL 642
>sp|Q9Y3R0|GRIP1_HUMAN Glutamate receptor-interacting protein
1 OS=Homo sapiens OX=9606 GN=GRIP1 PE=1 SV=3
Length=1128
Score = 53.1 bits (126), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 27/68 (40%), Positives = 39/68 (57%), Gaps = 3/68 (4%)
Query 266 PLGATVRNE---MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
PLG T+ D +IIS + KGG AE++G +H GD +L IN ++GK ++E LL
Sbjct 682 PLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQ 741
Query 323 DMHGTLTF 330
T+T
Sbjct 742 MAGETVTL 749
Score = 42.4 bits (98), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 33/133 (25%), Positives = 56/133 (42%), Gaps = 8/133 (6%)
Query 211 LLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGAT 270
LL T H +A+ + K QE L D V +S+ G +V + K LG
Sbjct 211 LLGTTHAEAMSIL--KQCGQEAALLIEYDVSVMDSVATASGPL--LVEVAKTPGASLGVA 266
Query 271 VRNEMDS----VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
+ M ++I +I A++ G LH GD +L I+G + + E L++
Sbjct 267 LTTSMCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTSMEYCTLAEATQFLANTTD 326
Query 327 TLTFVLIPSQQIK 339
+ ++P Q +
Sbjct 327 QVKLEILPHHQTR 339
Score = 36.2 bits (82), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 21/70 (30%), Positives = 37/70 (53%), Gaps = 5/70 (7%)
Query 257 VRIEKARDIPLGATV-----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
V++ K ++ LG T+ R D ++IS I KG A ++G L GD++L I+ I +
Sbjct 574 VKLPKKHNVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDN 633
Query 312 KDVNEVFDLL 321
+ + +L
Sbjct 634 CSMEDAVQIL 643
Score = 36.2 bits (82), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 16/50 (32%), Positives = 28/50 (56%), Gaps = 0/50 (0%)
Query 272 RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
RN+ V+I+ + GG A++ G + GD +L ++GI + G E +L
Sbjct 174 RNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSIL 223
>sp|A1A5G4|MAGI3_XENTR Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 3 OS=Xenopus tropicalis
OX=8364 GN=magi3 PE=2 SV=1
Length=1107
Score = 53.1 bits (126), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 23/52 (44%), Positives = 33/52 (63%), Gaps = 0/52 (0%)
Query 507 FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGT 558
+ +P TTRS RD EV G DY+F+S + F+A +G +E G ++ N YGT
Sbjct 135 YLRTIPCTTRSPRDGEVPGVDYNFISVEQFKALEDSGVLLESGTYDGNFYGT 186
Score = 42.0 bits (97), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 18/47 (38%), Positives = 31/47 (66%), Gaps = 0/47 (0%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD 323
++ I I+ GAAEK G L DE++ I+G+ ++GK +V DL+++
Sbjct 750 AIYIGAIIPLGAAEKDGRLRAADELICIDGVPVKGKSHKQVLDLMTN 796
Score = 34.3 bits (77), Expect = 4.4, Method: Compositional matrix adjust.
Identities = 17/64 (27%), Positives = 33/64 (52%), Gaps = 0/64 (0%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
I R+++G A++ L GD + +NG I + + L+ D T+T +I ++ +
Sbjct 884 IGRVIEGSPADRCRKLKVGDRISAVNGQSIVELSHDNIVQLIKDAGNTVTLTVIAEEEHR 943
Query 340 PPPA 343
PP+
Sbjct 944 GPPS 947
>sp|Q9C0E4|GRIP2_HUMAN Glutamate receptor-interacting protein
2 OS=Homo sapiens OX=9606 GN=GRIP2 PE=1 SV=4
Length=1043
Score = 52.8 bits (125), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 32/100 (32%), Positives = 53/100 (53%), Gaps = 7/100 (7%)
Query 266 PLGATVRNE---MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
PLG T+ D ++IS + K G AE++G +H GD +L IN + ++G+ ++E LL
Sbjct 665 PLGITISGTEEPFDPIVISGLTKRGLAERTGAIHVGDRILAINNVSLKGRPLSEAIHLLQ 724
Query 323 DMHGTLTFVLIPSQQIKPP--PAKETVIHVKAHFDYDPSD 360
T+T + +Q+ P P K + + D DP+D
Sbjct 725 VAGETVTLKI--KKQLDRPLLPRKSGSLSETSDADEDPAD 762
Score = 40.0 bits (92), Expect = 0.077, Method: Compositional matrix adjust.
Identities = 31/92 (34%), Positives = 45/92 (49%), Gaps = 14/92 (15%)
Query 222 LAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV----RNEMDS 277
LAH V E E + E V S G + V++ K R + LG T+ R +
Sbjct 533 LAHKVVLEVEFDVA----ESVIPSSGTFH------VKLPKKRSVELGITISSASRKRGEP 582
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+IIS I KG A ++G L GD++L I+ I +
Sbjct 583 LIISDIKKGSVAHRTGTLEPGDKLLAIDNIRL 614
Score = 35.4 bits (80), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 40/89 (45%), Gaps = 1/89 (1%)
Query 254 VKIVRIE-KARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
V+IV+ A I L T + I RI ++SG LH GD +L I+G +
Sbjct 249 VEIVKTPGSALGISLTTTSLRNKSVITIDRIKPASVVDRSGALHPGDHILSIDGTSMEHC 308
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
+ E LL+ + + ++P Q + P
Sbjct 309 SLLEATKLLASISEKVRLEILPVPQSQRP 337
>sp|Q5TCQ9|MAGI3_HUMAN Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 3 OS=Homo sapiens OX=9606
GN=MAGI3 PE=1 SV=3
Length=1481
Score = 52.8 bits (125), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 22/52 (42%), Positives = 33/52 (63%), Gaps = 0/52 (0%)
Query 507 FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGT 558
+ +P TTR+ RD EV G DY+F+S + F+A +G +E G ++ N YGT
Sbjct 139 YLRTIPCTTRAPRDGEVPGVDYNFISVEQFKALEESGALLESGTYDGNFYGT 190
Score = 43.5 bits (101), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 20/46 (43%), Positives = 30/46 (65%), Gaps = 0/46 (0%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
S+ I I+ GAAEK G L DE++ I+GI ++GK +V DL++
Sbjct 749 SIYIGAIIPLGAAEKDGRLRAADELMCIDGIPVKGKSHKQVLDLMT 794
Score = 36.6 bits (83), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 18/64 (28%), Positives = 33/64 (52%), Gaps = 0/64 (0%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
I R+++G A++ G L GD + +NG I + + L+ D T+T +I ++
Sbjct 882 IGRVIEGSPADRCGKLKVGDHISAVNGQSIVELSHDNIVQLIKDAGVTVTLTVIAEEEHH 941
Query 340 PPPA 343
PP+
Sbjct 942 GPPS 945
Score = 35.0 bits (79), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 27/117 (23%), Positives = 51/117 (44%), Gaps = 4/117 (3%)
Query 224 HDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRI 283
H +A+ + + + R +++G Y V++ R + L M + I R+
Sbjct 995 HKHLAQPDTAVISVVGSRHNQNLGCY---PVELERGPRGFGFSLRGGKEYNM-GLFILRL 1050
Query 284 VKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
+ G A K G +H GD+++EING +G +L+ + +L P + P
Sbjct 1051 AEDGPAIKDGRIHVGDQIVEINGEPTQGITHTRAIELIQAGGNKVLLLLRPGTGLIP 1107
>sp|Q9EQJ9|MAGI3_MOUSE Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 3 OS=Mus musculus OX=10090
GN=Magi3 PE=1 SV=2
Length=1476
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 22/52 (42%), Positives = 33/52 (63%), Gaps = 0/52 (0%)
Query 507 FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGT 558
+ +P TTR+ RD EV G DY+F+S + F+A +G +E G ++ N YGT
Sbjct 141 YLRTIPCTTRAPRDGEVPGVDYNFISVEQFKALEESGALLESGTYDGNFYGT 192
Score = 43.5 bits (101), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 20/46 (43%), Positives = 30/46 (65%), Gaps = 0/46 (0%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
S+ I I+ GAAEK G L DE++ I+GI ++GK +V DL++
Sbjct 752 SIYIGAIIPLGAAEKDGRLRAADELMCIDGIPVKGKSHKQVLDLMT 797
Score = 37.0 bits (84), Expect = 0.74, Method: Compositional matrix adjust.
Identities = 40/171 (23%), Positives = 70/171 (41%), Gaps = 23/171 (13%)
Query 224 HDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRI 283
H +A+ + + + R +S+G Y V++ R + L M + I R+
Sbjct 996 HKHLAQPDTAVISVVGSRHNQSLGCY---PVELERGPRGFGFSLRGGKEYNM-GLFILRL 1051
Query 284 VKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP--- 340
+ G A K G +H GD+++EING +G +L+ + +L P + P
Sbjct 1052 AEDGPAIKDGRIHVGDQIVEINGEPTQGITHTRAIELIQAGGNKVLLLLRPGTGLIPDHG 1111
Query 341 -----PPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQED 386
P+ VI +D P P +P +F++ HV + ED
Sbjct 1112 DWDTNSPSSSNVI-----YDEQP---PPLPSSHSASTFEES---HVPATED 1151
Score = 36.2 bits (82), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 17/64 (27%), Positives = 32/64 (50%), Gaps = 0/64 (0%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
I R++ G A++ G L GD + +NG I + + L+ D T+T ++ ++
Sbjct 883 IGRVIDGSPADRCGGLKVGDHISAVNGQSIVDLSHDNIVQLIKDAGVTVTLTVVAEEEHH 942
Query 340 PPPA 343
PP+
Sbjct 943 GPPS 946
>sp|Q9JK71|MAGI3_RAT Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 3 OS=Rattus norvegicus OX=10116
GN=Magi3 PE=1 SV=2
Length=1470
Score = 52.0 bits (123), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 22/49 (45%), Positives = 32/49 (65%), Gaps = 0/49 (0%)
Query 510 AVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGT 558
+P TTR+ RD EV G DY+F+S + F+A +G +E G ++ N YGT
Sbjct 144 TIPCTTRAPRDGEVPGVDYNFISVEQFKALEESGALLESGTYDGNFYGT 192
Score = 43.5 bits (101), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 20/46 (43%), Positives = 30/46 (65%), Gaps = 0/46 (0%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
S+ I I+ GAAEK G L DE++ I+GI ++GK +V DL++
Sbjct 752 SIYIGAIIPLGAAEKDGRLRAADELMCIDGIPVKGKSHKQVLDLMT 797
Score = 36.6 bits (83), Expect = 0.98, Method: Compositional matrix adjust.
Identities = 28/117 (24%), Positives = 51/117 (44%), Gaps = 4/117 (3%)
Query 224 HDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRI 283
H +A+ + + + R +S+G Y V++ R + L M + I R+
Sbjct 996 HKHLAQPDTAVISVVGSRHSQSLGCY---PVELERGPRGFGFSLRGGKEYNM-GLFILRL 1051
Query 284 VKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
+ G A K G +H GD+++EING +G +L+ + +L P + P
Sbjct 1052 AEDGPAIKDGRIHVGDQIVEINGEPTQGITHTRAIELIQAGGNKVLLLLRPGTGLIP 1108
Score = 36.2 bits (82), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 17/64 (27%), Positives = 32/64 (50%), Gaps = 0/64 (0%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
I R++ G A++ G L GD + +NG I + + L+ D T+T ++ ++
Sbjct 883 IGRVIDGSPADRCGRLKVGDHISAVNGQSIVDLSHDNIVQLIKDAGVTVTLTVVAEEEHH 942
Query 340 PPPA 343
PP+
Sbjct 943 GPPS 946
>sp|Q5F488|MAGI3_CHICK Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 3 OS=Gallus gallus OX=9031
GN=MAGI3 PE=2 SV=1
Length=1128
Score = 50.8 bits (120), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 21/52 (40%), Positives = 32/52 (62%), Gaps = 0/52 (0%)
Query 507 FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGT 558
+ +P TTR+ RD EV G DY+F+ + F+A +G +E G ++ N YGT
Sbjct 141 YLRTIPCTTRAPRDGEVPGVDYNFIPVEQFKALEESGALLESGTYDGNFYGT 192
Score = 41.2 bits (95), Expect = 0.036, Method: Compositional matrix adjust.
Identities = 18/45 (40%), Positives = 29/45 (64%), Gaps = 0/45 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
+ I I+ GAAEK G L DE++ I+G+ ++GK +V DL++
Sbjct 752 IYIGAIIPLGAAEKDGRLRAADELMCIDGVPVKGKSHKQVLDLMT 796
Score = 33.9 bits (76), Expect = 5.8, Method: Compositional matrix adjust.
Identities = 18/64 (28%), Positives = 31/64 (48%), Gaps = 0/64 (0%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQ 336
+ I R+ + G A K G +H GD+++EING +G +L+ + +L P
Sbjct 1047 GLFILRLAEDGPAVKDGRVHVGDQIVEINGEPTQGITHTRAIELIQAGGNKVLLLLRPGT 1106
Query 337 QIKP 340
+ P
Sbjct 1107 GLIP 1110
Score = 33.9 bits (76), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 16/64 (25%), Positives = 32/64 (50%), Gaps = 0/64 (0%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
I R++ G A++ G L GD + +NG I + + L+ D +T ++ ++ +
Sbjct 883 IGRVIDGSPADQCGKLKVGDRISAVNGQSIVELSHDSIVQLIKDAGHVVTLTVVAEEEHR 942
Query 340 PPPA 343
PP+
Sbjct 943 GPPS 946
>sp|Q9WTW1|GRIP2_RAT Glutamate receptor-interacting protein 2
OS=Rattus norvegicus OX=10116 GN=Grip2 PE=1 SV=1
Length=1043
Score = 50.8 bits (120), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 25/68 (37%), Positives = 39/68 (57%), Gaps = 3/68 (4%)
Query 266 PLGATVRNE---MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
PLG T+ D +IIS + K G AE++G +H GD +L IN + ++G+ ++E LL
Sbjct 667 PLGITISGTEEPFDPIIISGLTKRGLAERTGAIHVGDRILAINSVSLKGRPLSEAIHLLQ 726
Query 323 DMHGTLTF 330
T+T
Sbjct 727 VAGETVTL 734
Score = 37.0 bits (84), Expect = 0.70, Method: Compositional matrix adjust.
Identities = 21/57 (37%), Positives = 33/57 (58%), Gaps = 4/57 (7%)
Query 257 VRIEKARDIPLGATV----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
V++ K R + LG T+ R + +IIS I KG A ++G L GD++L I+ I +
Sbjct 560 VKLPKRRGVELGITISSASRKRGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRL 616
Score = 37.0 bits (84), Expect = 0.74, Method: Compositional matrix adjust.
Identities = 28/97 (29%), Positives = 46/97 (47%), Gaps = 10/97 (10%)
Query 256 IVRIEKARDIPLGATV-----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
+V I K LG ++ RN+ ++ I RI ++SG LH GD +L I+G
Sbjct 253 VVEIAKTPGSALGISLTTGSHRNK-PAITIDRIKPASVVDRSGALHAGDHILAIDGTSTE 311
Query 311 GKDVNEVFDLLSDMHGTLTFVLIPSQQ----IKPPPA 343
+ E LL+ + + ++P+ Q +KPP A
Sbjct 312 HCSLVEATKLLASVTEKVRLEILPAPQSRRPLKPPEA 348
>sp|A8E0R9|GRIP2_XENLA Glutamate receptor-interacting protein
2 OS=Xenopus laevis OX=8355 GN=grip2 PE=2 SV=2
Length=1083
Score = 50.4 bits (119), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 26/68 (38%), Positives = 39/68 (57%), Gaps = 3/68 (4%)
Query 266 PLGATVRNE---MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
PLG T+ D ++IS + K G AE++G +H GD +L IN I ++GK ++E LL
Sbjct 676 PLGITISGTEEPFDPIVISGLTKRGLAERTGAIHIGDRILAINNISLKGKPLSEAIHLLQ 735
Query 323 DMHGTLTF 330
T+T
Sbjct 736 MAGETVTL 743
Score = 36.2 bits (82), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 21/68 (31%), Positives = 37/68 (54%), Gaps = 3/68 (4%)
Query 257 VRIEKARDIPLGATV---RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
V++ K + + LG T+ R + +IIS I KG A ++G L GD++L I+ I +
Sbjct 570 VKLPKRKGVELGITISSSRKPGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDNCS 629
Query 314 VNEVFDLL 321
+ + +L
Sbjct 630 MEDAVQIL 637
Score = 33.9 bits (76), Expect = 7.3, Method: Compositional matrix adjust.
Identities = 40/160 (25%), Positives = 67/160 (42%), Gaps = 19/160 (12%)
Query 210 ALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLG- 268
+L N H AL + E Q+E D + +++ G +V I K LG
Sbjct 216 SLHNITHTDALSILRQCSQEGVFQIE--YDVALMDTVTNASGPL--LVEIAKTPGSTLGI 271
Query 269 ----ATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
T RN+ ++I ++ ++ G LH GD +L I+G E LL+ +
Sbjct 272 SLSTGTHRNKQ-VIVIDKVKPASVVDRCGALHPGDHILSIDGTSTEHCTQMEATQLLASI 330
Query 325 HGTLTFVLIPSQQ----IKPPPAKETVIHVKA--HFDYDP 358
+ ++P+ ++PP ETV K+ H +DP
Sbjct 331 IENVKLEILPAHHSRLPLRPP---ETVKVQKSDHHHCWDP 367
>sp|Q60631|GRB2_MOUSE Growth factor receptor-bound protein 2 OS=Mus
musculus OX=10090 GN=Grb2 PE=1 SV=1
Length=217
Score = 46.6 bits (109), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 7/60 (12%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+V+A FD+DP +D ELG F++GD +HV+ DPNWW+ G P + P
Sbjct 160 YVQALFDFDPQEDG-----ELG--FRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTP 212
>sp|P62994|GRB2_RAT Growth factor receptor-bound protein 2 OS=Rattus
norvegicus OX=10116 GN=Grb2 PE=1 SV=1
Length=217
Score = 46.6 bits (109), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 7/60 (12%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+V+A FD+DP +D ELG F++GD +HV+ DPNWW+ G P + P
Sbjct 160 YVQALFDFDPQEDG-----ELG--FRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTP 212
>sp|Q5R4J7|GRB2_PONAB Growth factor receptor-bound protein 2 OS=Pongo
abelii OX=9601 GN=GRB2 PE=2 SV=1
Length=217
Score = 46.6 bits (109), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 7/60 (12%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+V+A FD+DP +D ELG F++GD +HV+ DPNWW+ G P + P
Sbjct 160 YVQALFDFDPQEDG-----ELG--FRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTP 212
>sp|P62993|GRB2_HUMAN Growth factor receptor-bound protein 2 OS=Homo
sapiens OX=9606 GN=GRB2 PE=1 SV=1
Length=217
Score = 46.6 bits (109), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 7/60 (12%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+V+A FD+DP +D ELG F++GD +HV+ DPNWW+ G P + P
Sbjct 160 YVQALFDFDPQEDG-----ELG--FRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTP 212
>sp|Q2KIB6|LIN7B_BOVIN Protein lin-7 homolog B OS=Bos taurus OX=9913
GN=LIN7B PE=2 SV=1
Length=201
Score = 46.2 bits (108), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 18/55 (33%), Positives = 34/55 (62%), Gaps = 0/55 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ ISR++ GG A++ G L GD++L +NG+ + G+ + +LL G++ V+
Sbjct 117 IYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVV 171
>sp|Q9HAP6|LIN7B_HUMAN Protein lin-7 homolog B OS=Homo sapiens
OX=9606 GN=LIN7B PE=1 SV=1
Length=207
Score = 46.2 bits (108), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 18/55 (33%), Positives = 34/55 (62%), Gaps = 0/55 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ ISR++ GG A++ G L GD++L +NG+ + G+ + +LL G++ V+
Sbjct 117 IYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVV 171
>sp|Q4L1J4|MAGI1_RAT Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 1 OS=Rattus norvegicus OX=10116
GN=Magi1 PE=1 SV=1
Length=1255
Score = 47.8 bits (112), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 33/96 (34%), Positives = 53/96 (55%), Gaps = 9/96 (9%)
Query 493 NELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFE 552
+EL+Q + + + + AVP TTRS R+ EV G DY F++ + F +G +E G +E
Sbjct 127 HELQQTIRD---NLYRHAVPCTTRSPREGEVPGVDYSFLTVKEFLDLEQSGTLLEVGTYE 183
Query 553 KNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS 588
N YGT + V SGK+ + T +L +L++
Sbjct 184 GNYYGTPKPPSQPV--SGKV----ITTDALHSLQSG 213
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 19/58 (33%), Positives = 34/58 (59%), Gaps = 0/58 (0%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
I RI++G A++ G L GD +L +NG I K +++ +L+ + T+T +IP +
Sbjct 1037 IGRIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKEAGNTVTLRIIPGDE 1094
Score = 34.3 bits (77), Expect = 5.6, Method: Compositional matrix adjust.
Identities = 20/54 (37%), Positives = 29/54 (54%), Gaps = 1/54 (2%)
Query 253 TVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEING 306
TV++ R K L MD ++ R+ + G AE+ G + GDE+LEING
Sbjct 1151 TVELERGAKGFGFSLRGGREYNMDLYVL-RLAEDGPAERCGKMRIGDEILEING 1203
>sp|Q96QZ7|MAGI1_HUMAN Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 1 OS=Homo sapiens OX=9606
GN=MAGI1 PE=1 SV=3
Length=1491
Score = 47.8 bits (112), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 30/82 (37%), Positives = 46/82 (56%), Gaps = 6/82 (7%)
Query 507 FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQV 566
+ AVP TTRS R+ EV G DY+F++ + F +G +E G +E N YGT + V
Sbjct 138 YRHAVPCTTRSPREGEVPGVDYNFLTVKEFLDLEQSGTLLEVGTYEGNYYGTPKPPSQPV 197
Query 567 INSGKICLLSLRTQSLKTLRNS 588
SGK+ + T +L +L++
Sbjct 198 --SGKV----ITTDALHSLQSG 213
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 19/58 (33%), Positives = 34/58 (59%), Gaps = 0/58 (0%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
I RI++G A++ G L GD +L +NG I K +++ +L+ + T+T +IP +
Sbjct 1038 IGRIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKEAGNTVTLRIIPGDE 1095
Score = 34.7 bits (78), Expect = 4.4, Method: Compositional matrix adjust.
Identities = 20/54 (37%), Positives = 29/54 (54%), Gaps = 1/54 (2%)
Query 253 TVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEING 306
TV++ R K L MD ++ R+ + G AE+ G + GDE+LEING
Sbjct 1152 TVELERGAKGFGFSLRGGREYNMDLYVL-RLAEDGPAERCGKMRIGDEILEING 1204
>sp|Q9Z252|LIN7B_RAT Protein lin-7 homolog B OS=Rattus norvegicus
OX=10116 GN=Lin7b PE=1 SV=1
Length=207
Score = 45.8 bits (107), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 18/55 (33%), Positives = 34/55 (62%), Gaps = 0/55 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ ISR++ GG A++ G L GD++L +NG+ + G+ + +LL G++ V+
Sbjct 117 IYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGSVKLVV 171
>sp|Q9ES64|USH1C_MOUSE Harmonin OS=Mus musculus OX=10090 GN=Ush1c
PE=1 SV=1
Length=910
Score = 47.4 bits (111), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 23/61 (38%), Positives = 41/61 (67%), Gaps = 2/61 (3%)
Query 248 QYGGETVKIVRIEK--ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
Q G+ V+++RI+K + D+ L V + + V++S + +GGAAE+ G + +GDE++ IN
Sbjct 747 QIAGKDVRLLRIKKEGSLDLALEGGVDSPVGKVVVSAVYEGGAAERHGGVVKGDEIMAIN 806
Query 306 G 306
G
Sbjct 807 G 807
Score = 42.0 bits (97), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 28/91 (31%), Positives = 47/91 (52%), Gaps = 4/91 (4%)
Query 234 LEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAE 290
L P+ + Y+ + +K VR+++ LG +VR ++ + IS ++KGG A+
Sbjct 65 LIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKGGQAD 124
Query 291 KSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
GL GDE++ ING I EV +L+
Sbjct 125 SVGL-QVGDEIVRINGYSISSCTHEEVINLI 154
>sp|O88951|LIN7B_MOUSE Protein lin-7 homolog B OS=Mus musculus
OX=10090 GN=Lin7b PE=1 SV=2
Length=207
Score = 45.4 bits (106), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 18/55 (33%), Positives = 34/55 (62%), Gaps = 0/55 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ ISR++ GG A++ G L GD++L +NG+ + G+ + +LL G++ V+
Sbjct 117 IYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGSVKLVV 171
>sp|Q94JM2|GMK3_ARATH Guanylate kinase 3, chloroplastic OS=Arabidopsis
thaliana OX=3702 GN=GK3 PE=2 SV=1
Length=282
Score = 46.2 bits (108), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 47/185 (25%), Positives = 84/185 (45%), Gaps = 12/185 (6%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I++ GP G++ + +L + ++ V T+R R EV G+DY FVSR F + +
Sbjct 91 IVISGPSGVGKDAVINKL-REVREGLHFVVTATSRPMRPGEVDGKDYFFVSRDQFLSMVE 149
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLR----NSDLKPYIIFI 597
+ +E+ G +++ + G+ +L + Q +TLR NS + +I +
Sbjct 150 NEELLEYALVYGEYKGIPKKQIQEFMAKGEDIVLRVDIQGAQTLRRILGNSAV--FIFLV 207
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD--LDKAYQEL 655
A + L+ + K EEL + RE E + FD +VN+ LD A +
Sbjct 208 AESELAMVERLIDR--KTESQEELLVRVATARE-EVRHLKNFDYVVVNAKGRLDDAVNRV 264
Query 656 LRLIN 660
+I+
Sbjct 265 ESIID 269
>sp|Q6RHR9|MAGI1_MOUSE Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 1 OS=Mus musculus OX=10090
GN=Magi1 PE=1 SV=1
Length=1471
Score = 47.4 bits (111), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 30/82 (37%), Positives = 45/82 (55%), Gaps = 6/82 (7%)
Query 507 FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQV 566
+ AVP TTRS R+ EV G DY F++ + F +G +E G +E N YGT + V
Sbjct 138 YRHAVPCTTRSPREGEVPGVDYSFLTVKEFLDLEQSGTLLEVGTYEGNYYGTPKPPSQPV 197
Query 567 INSGKICLLSLRTQSLKTLRNS 588
SGK+ + T +L +L++
Sbjct 198 --SGKV----ITTDALHSLQSG 213
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 19/69 (28%), Positives = 36/69 (52%), Gaps = 0/69 (0%)
Query 269 ATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTL 328
++V RI++G A++ G L GD +L +NG I K +++ +L+ + T+
Sbjct 1007 SSVSRPEAGTTFGRIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKEAGNTV 1066
Query 329 TFVLIPSQQ 337
T +IP +
Sbjct 1067 TLRIIPGDE 1075
Score = 34.3 bits (77), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 20/54 (37%), Positives = 29/54 (54%), Gaps = 1/54 (2%)
Query 253 TVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEING 306
TV++ R K L MD ++ R+ + G AE+ G + GDE+LEING
Sbjct 1132 TVELERGAKGFGFSLRGGREYNMDLYVL-RLAEDGPAERCGKMRIGDEILEING 1184
>sp|Q5F425|LIN7C_CHICK Protein lin-7 homolog C OS=Gallus gallus
OX=9031 GN=LIN7C PE=1 SV=1
Length=197
Score = 44.7 bits (104), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 19/55 (35%), Positives = 33/55 (60%), Gaps = 0/55 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ ISRI+ GG A++ G L GD++L +NG+ + G+ + +LL G + V+
Sbjct 117 IYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVV 171
>sp|Q3MHQ0|USH1C_BOVIN Harmonin OS=Bos taurus OX=9913 GN=USH1C
PE=2 SV=1
Length=551
Score = 46.2 bits (108), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 23/61 (38%), Positives = 41/61 (67%), Gaps = 2/61 (3%)
Query 248 QYGGETVKIVRIEK--ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
Q G+ V+++R++K A D+ L V + + V++S + +GGAAE+ G + +GDE++ IN
Sbjct 447 QIMGKDVRLLRVKKEGALDLALEGGVDSPIGKVVVSAVYEGGAAERHGGIVKGDEIMAIN 506
Query 306 G 306
G
Sbjct 507 G 507
Score = 36.6 bits (83), Expect = 0.87, Method: Compositional matrix adjust.
Identities = 27/91 (30%), Positives = 46/91 (51%), Gaps = 4/91 (4%)
Query 234 LEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAE 290
L P+ + Y+ + +K VR+++ LG +VR ++ + IS ++K G A+
Sbjct 65 LIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKDGQAD 124
Query 291 KSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
GL GDE++ ING I EV +L+
Sbjct 125 SVGL-QVGDEIVRINGYSISSCTHEEVINLI 154
>sp|Q792I0|LIN7C_RAT Protein lin-7 homolog C OS=Rattus norvegicus
OX=10116 GN=Lin7c PE=1 SV=1
Length=197
Score = 44.7 bits (104), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 19/55 (35%), Positives = 33/55 (60%), Gaps = 0/55 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ ISRI+ GG A++ G L GD++L +NG+ + G+ + +LL G + V+
Sbjct 117 IYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVV 171
>sp|Q5RAA5|LIN7C_PONAB Protein lin-7 homolog C OS=Pongo abelii
OX=9601 GN=LIN7C PE=2 SV=1
Length=197
Score = 44.7 bits (104), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 19/55 (35%), Positives = 33/55 (60%), Gaps = 0/55 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ ISRI+ GG A++ G L GD++L +NG+ + G+ + +LL G + V+
Sbjct 117 IYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVV 171
>sp|O88952|LIN7C_MOUSE Protein lin-7 homolog C OS=Mus musculus
OX=10090 GN=Lin7c PE=1 SV=2
Length=197
Score = 44.7 bits (104), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 19/55 (35%), Positives = 33/55 (60%), Gaps = 0/55 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ ISRI+ GG A++ G L GD++L +NG+ + G+ + +LL G + V+
Sbjct 117 IYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVV 171
>sp|Q9NUP9|LIN7C_HUMAN Protein lin-7 homolog C OS=Homo sapiens
OX=9606 GN=LIN7C PE=1 SV=1
Length=197
Score = 44.7 bits (104), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 19/55 (35%), Positives = 33/55 (60%), Gaps = 0/55 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ ISRI+ GG A++ G L GD++L +NG+ + G+ + +LL G + V+
Sbjct 117 IYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVV 171
>sp|Q0P5F3|LIN7C_BOVIN Protein lin-7 homolog C OS=Bos taurus OX=9913
GN=LIN7C PE=2 SV=1
Length=197
Score = 44.7 bits (104), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 19/55 (35%), Positives = 33/55 (60%), Gaps = 0/55 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ ISRI+ GG A++ G L GD++L +NG+ + G+ + +LL G + V+
Sbjct 117 IYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVV 171
>sp|Q99NH2|PARD3_MOUSE Partitioning defective 3 homolog OS=Mus
musculus OX=10090 GN=Pard3 PE=1 SV=2
Length=1333
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 23/74 (31%), Positives = 42/74 (57%), Gaps = 7/74 (9%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+RD+ +G + + + I+ GAA + G L GD ++E+NG+++ GK EV LL
Sbjct 477 SRDVTIGGSA-----PIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLAGKSQEEVVSLL 531
Query 322 --SDMHGTLTFVLI 333
+ M GT++ ++
Sbjct 532 RSTKMEGTVSLLVF 545
Score = 35.0 bits (79), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 15/44 (34%), Positives = 24/44 (55%), Gaps = 0/44 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ + I+ GGAA K G L D+++ +NG + GK E + L
Sbjct 619 IFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKANQEAMETL 662
Score = 33.5 bits (75), Expect = 9.0, Method: Compositional matrix adjust.
Identities = 13/35 (37%), Positives = 23/35 (66%), Gaps = 0/35 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
+++ R+ KGG AE+ L HE D ++ IN ++R +
Sbjct 301 LLVKRLEKGGKAEQENLFHENDCIVRINDGDLRNR 335
>sp|Q9Z340|PARD3_RAT Partitioning defective 3 homolog OS=Rattus
norvegicus OX=10116 GN=Pard3 PE=1 SV=1
Length=1337
Score = 46.2 bits (108), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 23/74 (31%), Positives = 42/74 (57%), Gaps = 7/74 (9%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+RD+ +G + + + I+ GAA + G L GD ++E+NG+++ GK EV LL
Sbjct 477 SRDVTIGGSA-----PIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLAGKSQEEVVSLL 531
Query 322 --SDMHGTLTFVLI 333
+ M GT++ ++
Sbjct 532 RSTKMEGTVSLLVF 545
Score = 35.0 bits (79), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 15/44 (34%), Positives = 24/44 (55%), Gaps = 0/44 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ + I+ GGAA K G L D+++ +NG + GK E + L
Sbjct 619 IFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKANQEAMETL 662
Score = 33.5 bits (75), Expect = 9.7, Method: Compositional matrix adjust.
Identities = 13/35 (37%), Positives = 23/35 (66%), Gaps = 0/35 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
+++ R+ KGG AE+ L HE D ++ IN ++R +
Sbjct 301 LLVKRLEKGGKAEQENLFHENDCIVRINDGDLRNR 335
>sp|Q80U72|SCRIB_MOUSE Protein scribble homolog OS=Mus musculus
OX=10090 GN=Scrib PE=1 SV=2
Length=1612
Score = 46.2 bits (108), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 5/82 (6%)
Query 256 IVRIEKARDIPL----GATVRNEMDS-VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
+VR EK + G+T D + ISRI +GGAA ++G L GD VL ING+++
Sbjct 851 LVRSEKGLGFSIAGGKGSTPYRAGDGGIFISRIAEGGAAHRAGTLQVGDRVLSINGVDMT 910
Query 311 GKDVNEVFDLLSDMHGTLTFVL 332
+ LL+ T++ +L
Sbjct 911 EARHDHAVSLLTAASPTISLLL 932
Score = 35.4 bits (80), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 29/112 (26%), Positives = 45/112 (40%), Gaps = 16/112 (14%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQ 336
V IS+++ G A + GL GD +L +NG ++R E L + L L+ +
Sbjct 1021 GVFISKVLPRGLAARCGL-RVGDRILAVNGQDVREATHQEAVSAL--LRPCLELCLLVRR 1077
Query 337 QIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPN 388
PP +E I P +LG+S + G H + DP
Sbjct 1078 DPPPPGMRELCIQ-------------KAPGEKLGISIRGGAKGHAGNPCDPT 1116
Score = 34.7 bits (78), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 27/111 (24%), Positives = 56/111 (50%), Gaps = 7/111 (6%)
Query 253 TVKIVRIEKARDIPL----GAT-VRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
T+ IVR I + G+T + + + + ISR+ + G A ++G+ GD++LE+NG+
Sbjct 714 TLTIVRQTGGLGISIAGGKGSTPYKGDDEGIFISRVSEEGPAARAGV-RVGDKLLEVNGV 772
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDP 358
++ + +E + L + + + ++P A T+ ++ DY P
Sbjct 773 ALQDAEHHEAVEALRGAGAAVQMRVWRERMVEPENAV-TITPLRPEDDYSP 822
>sp|Q8TEW0|PARD3_HUMAN Partitioning defective 3 homolog OS=Homo
sapiens OX=9606 GN=PARD3 PE=1 SV=2
Length=1356
Score = 45.8 bits (107), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 23/74 (31%), Positives = 42/74 (57%), Gaps = 7/74 (9%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+RD+ +G + + + I+ GAA + G L GD ++E+NG+++ GK EV LL
Sbjct 477 SRDVTIGGSA-----PIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLL 531
Query 322 --SDMHGTLTFVLI 333
+ M GT++ ++
Sbjct 532 RSTKMEGTVSLLVF 545
Score = 34.3 bits (77), Expect = 5.3, Method: Compositional matrix adjust.
Identities = 14/44 (32%), Positives = 24/44 (55%), Gaps = 0/44 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ + I+ GGAA K G L D+++ +NG + GK + + L
Sbjct 619 IFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETL 662
>sp|Q0U6X7|HSE1_PHANO Class E vacuolar protein-sorting machinery
protein HSE1 OS=Phaeosphaeria nodorum (strain SN15 / ATCC
MYA-4574 / FGSC 10173) OX=321614 GN=HSE1 PE=3 SV=1
Length=618
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 53/192 (28%), Positives = 84/192 (44%), Gaps = 38/192 (20%)
Query 336 QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELG-LSFQKGDILHVISQEDPNWWQAYR 394
Q ++P TV V+A FD+ PS E G L F+KGDI+ V+ +WW+
Sbjct 207 QPVQPGTTAATVSRVRALFDFQPS--------EPGELQFKKGDIIAVLESVYKDWWKGSL 258
Query 395 EGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYN--- 451
G+ G+ P ++ ++ ++ +E KE + +++ +N +K +L
Sbjct 259 RGN------TGIFPLNYVEKLQDPTREELE--KEAQTEAEVFAQIRNVEKLLALLSTNTQ 310
Query 452 ANKNDDYDNEEILTYEEMSLYHQP-ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASA 510
A D DNEEI LYH A R + I LIG +++KD F
Sbjct 311 AGGGDGRDNEEI-----TELYHSTLAIRPKLIELIG------------KYSQKKDDFTQL 353
Query 511 VPHTTRSRRDQE 522
++RRD E
Sbjct 354 NEKFIKARRDYE 365
>sp|Q9Y6V0|PCLO_HUMAN Protein piccolo OS=Homo sapiens OX=9606
GN=PCLO PE=1 SV=5
Length=5142
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 27/75 (36%), Positives = 41/75 (55%), Gaps = 14/75 (19%)
Query 257 VRIEKARDIP-----LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
+RI ++IP +GA I++I+ GG+AE++G L EG +VLE NGI +
Sbjct 4515 IRIVGGKEIPGHSGEIGA---------YIAKILPGGSAEQTGKLMEGMQVLEWNGIPLTS 4565
Query 312 KDVNEVFDLLSDMHG 326
K EV ++S G
Sbjct 4566 KTYEEVQSIISQQSG 4580
>sp|Q14160|SCRIB_HUMAN Protein scribble homolog OS=Homo sapiens
OX=9606 GN=SCRIB PE=1 SV=5
Length=1630
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 20/56 (36%), Positives = 32/56 (57%), Gaps = 0/56 (0%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ +SRI +GGAA ++G L GD VL ING+++ + LL+ T+ +L
Sbjct 891 GIFVSRIAEGGAAHRAGTLQVGDRVLSINGVDVTEARHDHAVSLLTAASPTIALLL 946
Score = 38.1 bits (87), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 22/83 (27%), Positives = 46/83 (55%), Gaps = 2/83 (2%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ + ISR+ + G A ++G+ GD++LE+NG+ ++G + +E + L GT + +
Sbjct 756 EGIFISRVSEEGPAARAGV-RVGDKLLEVNGVALQGAEHHEAVEALRGA-GTAVQMRVWR 813
Query 336 QQIKPPPAKETVIHVKAHFDYDP 358
+++ P T+ ++ DY P
Sbjct 814 ERMVEPENAVTITPLRPEDDYSP 836
Score = 37.4 bits (85), Expect = 0.58, Method: Compositional matrix adjust.
Identities = 37/146 (25%), Positives = 58/146 (40%), Gaps = 28/146 (19%)
Query 254 VKIVRIEKARDIPLGATVRNEMD-----------SVIISRIVKGGAAEKSGLLHEGDEVL 302
V+ +R+ +A PLG ++ D V IS+++ G A +SGL GD +L
Sbjct 1002 VEEIRLPRAGG-PLGLSIVGGSDHSSHPFGVQEPGVFISKVLPRGLAARSGL-RVGDRIL 1059
Query 303 EINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDP 362
+NG ++R E L + L L+ + PP +E I
Sbjct 1060 AVNGQDVRDATHQEAVSAL--LRPCLELSLLVRRDPAPPGLRELCIQ------------- 1104
Query 363 YVPCRELGLSFQKGDILHVISQEDPN 388
P LG+S + G H + DP
Sbjct 1105 KAPGERLGISIRGGARGHAGNPRDPT 1130
>sp|Q29498|NOS1_SHEEP Nitric oxide synthase 1 OS=Ovis aries OX=9940
GN=NOS1 PE=2 SV=3
Length=1463
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 27/79 (34%), Positives = 43/79 (54%), Gaps = 2/79 (3%)
Query 257 VRIEKARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
VR+ K + LG V+ + VIIS +++GGAAE+SGL+ GD +L +NG +
Sbjct 18 VRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVNGQPLVDLSY 77
Query 315 NEVFDLLSDMHGTLTFVLI 333
+ ++L + VLI
Sbjct 78 DSALEVLRGIASETHVVLI 96
>sp|P87379|GRB2A_XENLA Growth factor receptor-bound protein 2-A
OS=Xenopus laevis OX=8355 GN=grb2-a PE=1 SV=2
Length=229
Score = 43.9 bits (102), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 19/44 (43%), Positives = 28/44 (64%), Gaps = 7/44 (16%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 392
+V+A FD+DP +D ELG F++GD + V+ DPNWW+
Sbjct 172 YVQALFDFDPQEDG-----ELG--FRRGDFIQVVDNSDPNWWKG 208
>sp|Q66II3|GRB2_XENTR Growth factor receptor-bound protein 2 OS=Xenopus
tropicalis OX=8364 GN=grb2 PE=2 SV=1
Length=229
Score = 43.5 bits (101), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 19/44 (43%), Positives = 28/44 (64%), Gaps = 7/44 (16%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 392
+V+A FD+DP +D ELG F++GD + V+ DPNWW+
Sbjct 172 YVQALFDFDPQEDG-----ELG--FRRGDFIQVVDNSDPNWWKG 208
>sp|P29475|NOS1_HUMAN Nitric oxide synthase 1 OS=Homo sapiens
OX=9606 GN=NOS1 PE=1 SV=2
Length=1434
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 27/79 (34%), Positives = 43/79 (54%), Gaps = 2/79 (3%)
Query 257 VRIEKARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
VR+ K + LG V+ + VIIS +++GGAAE+SGL+ GD +L +NG +
Sbjct 18 VRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVNGRPLVDLSY 77
Query 315 NEVFDLLSDMHGTLTFVLI 333
+ ++L + VLI
Sbjct 78 DSALEVLRGIASETHVVLI 96
>sp|O19132|NOS1_RABIT Nitric oxide synthase 1 OS=Oryctolagus cuniculus
OX=9986 GN=NOS1 PE=2 SV=1
Length=1435
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 27/79 (34%), Positives = 43/79 (54%), Gaps = 2/79 (3%)
Query 257 VRIEKARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
VR+ K + LG V+ + VIIS +++GGAAE+SGL+ GD +L +NG +
Sbjct 18 VRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVNGRPLVDLSY 77
Query 315 NEVFDLLSDMHGTLTFVLI 333
+ ++L + VLI
Sbjct 78 DSALEVLRGVASETHVVLI 96
>sp|Q9Z250|LIN7A_RAT Protein lin-7 homolog A OS=Rattus norvegicus
OX=10116 GN=Lin7a PE=1 SV=2
Length=232
Score = 43.5 bits (101), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 19/55 (35%), Positives = 33/55 (60%), Gaps = 0/55 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ ISRI+ GG AE+ G L GD++L +NG+ + G+ + +LL ++ V+
Sbjct 132 IYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVV 186
>sp|Q8JZS0|LIN7A_MOUSE Protein lin-7 homolog A OS=Mus musculus
OX=10090 GN=Lin7a PE=1 SV=2
Length=233
Score = 43.5 bits (101), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 19/55 (35%), Positives = 33/55 (60%), Gaps = 0/55 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ ISRI+ GG AE+ G L GD++L +NG+ + G+ + +LL ++ V+
Sbjct 132 IYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVV 186
>sp|O14910|LIN7A_HUMAN Protein lin-7 homolog A OS=Homo sapiens
OX=9606 GN=LIN7A PE=1 SV=2
Length=233
Score = 43.5 bits (101), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 19/55 (35%), Positives = 33/55 (60%), Gaps = 0/55 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ ISRI+ GG AE+ G L GD++L +NG+ + G+ + +LL ++ V+
Sbjct 132 IYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVV 186
>sp|Q32LM6|LIN7A_BOVIN Protein lin-7 homolog A OS=Bos taurus OX=9913
GN=LIN7A PE=2 SV=1
Length=233
Score = 43.5 bits (101), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 19/55 (35%), Positives = 33/55 (60%), Gaps = 0/55 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ ISRI+ GG AE+ G L GD++L +NG+ + G+ + +LL ++ V+
Sbjct 132 IYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVV 186
>sp|Q4H4B6|SCRIB_DANRE Protein scribble homolog OS=Danio rerio
OX=7955 GN=scrib PE=1 SV=1
Length=1724
Score = 44.7 bits (104), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 23/66 (35%), Positives = 39/66 (59%), Gaps = 1/66 (2%)
Query 268 GATVRNEMDS-VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
G+T+ D+ + ISRI +GGAA + +L GD V+ ING+++ ++ LL+
Sbjct 886 GSTLYRVGDTGIFISRIAEGGAAHRDNILQVGDRVISINGVDMTEARHDQAVALLTGTSP 945
Query 327 TLTFVL 332
T+T V+
Sbjct 946 TITLVV 951
Score = 39.7 bits (91), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 51/111 (46%), Gaps = 18/111 (16%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE-VFDLLSDMHGTLTFVLIPSQ 336
V IS+++ G A +SGL GD +LE+N I++R E V LLS+ V +
Sbjct 1037 VFISKVIPNGLASQSGL-RVGDRILEVNSIDLRHATHQEAVRALLSNKQEIRMLV---RR 1092
Query 337 QIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDP 387
PP +E VIH + P +LG+S + G H + DP
Sbjct 1093 DPSPPGMQEIVIHKQ-------------PGEKLGISIRGGAKGHAGNPFDP 1130
Score = 37.0 bits (84), Expect = 0.72, Method: Compositional matrix adjust.
Identities = 24/98 (24%), Positives = 50/98 (51%), Gaps = 7/98 (7%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ + ISR+ + G A ++G+ GD++LE+NG+++ G + + + L + + ++
Sbjct 759 EGIFISRVSEEGPAARAGV-KVGDKLLEVNGVDLHGAEHHTAVEALRNSGAAVVMTVLRE 817
Query 336 QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSF 373
+ ++P A T ++ DY P + R GL F
Sbjct 818 RMVEPENAI-TTTPLRPEDDYFPRER-----RSSGLPF 849
>sp|Q6DFG0|RH21A_XENLA Rho GTPase-activating protein 21-A OS=Xenopus
laevis OX=8355 GN=arhgap21-a PE=2 SV=1
Length=1926
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 18/60 (30%), Positives = 37/60 (62%), Gaps = 1/60 (2%)
Query 275 MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP 334
MD++ + ++ +GG A ++GL GD ++++NG + GK ++V L+ + TL ++P
Sbjct 102 MDTIFVKQVKEGGPAHEAGLC-TGDRIIKVNGESVIGKTYSQVIALIQNSDSTLELSVMP 160
>sp|A2RUV4|RHG21_XENTR Rho GTPase-activating protein 21 OS=Xenopus
tropicalis OX=8364 GN=arhgap21 PE=2 SV=1
Length=1935
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 18/60 (30%), Positives = 37/60 (62%), Gaps = 1/60 (2%)
Query 275 MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP 334
MD++ + ++ +GG A ++GL GD ++++NG + GK ++V L+ + TL ++P
Sbjct 103 MDTIFVKQVKEGGPAHEAGLC-TGDRIIKVNGESVIGKTYSQVIALIQNSDSTLELSVMP 161
>sp|Q9WVQ1|MAGI2_MOUSE Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 2 OS=Mus musculus OX=10090
GN=Magi2 PE=1 SV=2
Length=1275
Score = 44.3 bits (103), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 20/52 (38%), Positives = 29/52 (56%), Gaps = 0/52 (0%)
Query 507 FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGT 558
+ VP TTR ++ EV G DY F++ + F +G +E G +E N YGT
Sbjct 134 YLRTVPCTTRPHKEGEVPGVDYIFITVEEFMELEKSGALLESGTYEDNYYGT 185
Score = 42.4 bits (98), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 28/96 (29%), Positives = 47/96 (49%), Gaps = 3/96 (3%)
Query 227 VAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIP-LGATVRNEMDSVIISRIVK 285
+ E Q+ P T R+ S Y V + R+E LG + ++I ++
Sbjct 751 IYESRQQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRILGGDEPGQ--PILIGAVIA 808
Query 286 GGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
G+A++ G LH GDE++ ++GI + GK V DL+
Sbjct 809 MGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLM 844
Score = 37.4 bits (85), Expect = 0.53, Method: Compositional matrix adjust.
Identities = 18/62 (29%), Positives = 32/62 (52%), Gaps = 0/62 (0%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
I RI+ G A++ L GD +L +NG I ++ L+ D ++T +IP +++
Sbjct 953 IGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELN 1012
Query 340 PP 341
P
Sbjct 1013 SP 1014
>sp|Q71M21|RH21B_XENLA Rho GTPase-activating protein 21-B OS=Xenopus
laevis OX=8355 GN=arhgap21-b PE=2 SV=1
Length=1902
Score = 44.3 bits (103), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 18/60 (30%), Positives = 37/60 (62%), Gaps = 1/60 (2%)
Query 275 MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP 334
MD++ + ++ +GG A ++GL GD ++++NG + GK ++V L+ + TL ++P
Sbjct 102 MDTIFVKQVKEGGPAHEAGLC-TGDRIIKVNGESVIGKTYSQVIALIQNSDSTLELSVMP 160
>sp|Q6GPJ9|GRB2B_XENLA Growth factor receptor-bound protein 2-B
OS=Xenopus laevis OX=8355 GN=grb2-b PE=1 SV=1
Length=229
Score = 42.4 bits (98), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 19/43 (44%), Positives = 27/43 (63%), Gaps = 7/43 (16%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 392
V+A FD+DP +D ELG F++GD + V+ DPNWW+
Sbjct 173 VQALFDFDPQEDG-----ELG--FRRGDFIQVVDNSDPNWWKG 208
>sp|O88382|MAGI2_RAT Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 2 OS=Rattus norvegicus OX=10116
GN=Magi2 PE=1 SV=1
Length=1277
Score = 43.9 bits (102), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 20/52 (38%), Positives = 29/52 (56%), Gaps = 0/52 (0%)
Query 507 FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGT 558
+ VP TTR ++ EV G DY F++ + F +G +E G +E N YGT
Sbjct 134 YLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYEDNYYGT 185
Score = 42.4 bits (98), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 28/96 (29%), Positives = 47/96 (49%), Gaps = 3/96 (3%)
Query 227 VAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIP-LGATVRNEMDSVIISRIVK 285
+ E Q+ P T R+ S Y V + R+E LG + ++I ++
Sbjct 752 IYESRQQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRILGGDEPGQ--PILIGAVIA 809
Query 286 GGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
G+A++ G LH GDE++ ++GI + GK V DL+
Sbjct 810 MGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLM 845
Score = 37.0 bits (84), Expect = 0.80, Method: Compositional matrix adjust.
Identities = 18/62 (29%), Positives = 32/62 (52%), Gaps = 0/62 (0%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
I RI+ G A++ L GD +L +NG I ++ L+ D ++T +IP +++
Sbjct 954 IGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELN 1013
Query 340 PP 341
P
Sbjct 1014 NP 1015
>sp|Q9NZM3|ITSN2_HUMAN Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2
PE=1 SV=3
Length=1697
Score = 43.9 bits (102), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 32/108 (30%), Positives = 50/108 (46%), Gaps = 26/108 (24%)
Query 331 VLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW 390
+L PS + + PA V V A +DY ++ E LSF KG +++V++++DP+WW
Sbjct 1114 LLGPSSE-RATPAFHPVCQVIAMYDYAANN-------EDELSFSKGQLINVMNKDDPDWW 1165
Query 391 QAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCA 438
Q G + GL P +K T + D + WCA
Sbjct 1166 QGEING------VTGLFPSN-------YVKMTTDSDPSQQ-----WCA 1195
>sp|Q86UL8|MAGI2_HUMAN Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 2 OS=Homo sapiens OX=9606
GN=MAGI2 PE=1 SV=3
Length=1455
Score = 43.9 bits (102), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 20/52 (38%), Positives = 29/52 (56%), Gaps = 0/52 (0%)
Query 507 FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGT 558
+ VP TTR ++ EV G DY F++ + F +G +E G +E N YGT
Sbjct 134 YLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGTYEDNYYGT 185
Score = 42.4 bits (98), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 28/96 (29%), Positives = 47/96 (49%), Gaps = 3/96 (3%)
Query 227 VAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIP-LGATVRNEMDSVIISRIVK 285
+ E Q+ P T R+ S Y V + R+E LG + ++I ++
Sbjct 752 IYESRQQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRILGGDEPGQ--PILIGAVIA 809
Query 286 GGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
G+A++ G LH GDE++ ++GI + GK V DL+
Sbjct 810 MGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLM 845
Score = 37.7 bits (86), Expect = 0.51, Method: Compositional matrix adjust.
Identities = 18/62 (29%), Positives = 32/62 (52%), Gaps = 0/62 (0%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
I RI+ G A++ L GD +L +NG I ++ L+ D ++T +IP +++
Sbjct 954 IGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELN 1013
Query 340 PP 341
P
Sbjct 1014 SP 1015
>sp|Q9QYX7|PCLO_MOUSE Protein piccolo OS=Mus musculus OX=10090
GN=Pclo PE=1 SV=4
Length=5068
Score = 43.9 bits (102), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 27/75 (36%), Positives = 40/75 (53%), Gaps = 14/75 (19%)
Query 257 VRIEKARDIP-----LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
+RI ++IP +GA I++I+ GG+AE SG L EG +VLE NGI +
Sbjct 4443 IRIVGGKEIPGHSGEIGA---------YIAKILPGGSAEHSGKLIEGMQVLEWNGIPLTS 4493
Query 312 KDVNEVFDLLSDMHG 326
K EV +++ G
Sbjct 4494 KTYEEVQSIINQQSG 4508
>sp|Q07883|GRB2_CHICK Growth factor receptor-bound protein 2 OS=Gallus
gallus OX=9031 GN=GRB2 PE=1 SV=1
Length=217
Score = 42.0 bits (97), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 7/60 (12%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+V+A FD+DP + E L F++GD + V+ DPNWW+ G P + P
Sbjct 160 YVQALFDFDPQE-------EGELGFRRGDFIQVLDNSDPNWWKGACHGQTGMFPRNYVTP 212
>sp|O15018|PDZD2_HUMAN PDZ domain-containing protein 2 OS=Homo
sapiens OX=9606 GN=PDZD2 PE=1 SV=4
Length=2839
Score = 43.1 bits (100), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 17/34 (50%), Positives = 26/34 (76%), Gaps = 0/34 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
++I R+ KGGAAE++G++ GDE+L ING + G
Sbjct 2777 LVIKRVYKGGAAEQAGIIEAGDEILAINGKPLVG 2810
Score = 42.7 bits (99), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 23/82 (28%), Positives = 39/82 (48%), Gaps = 6/82 (7%)
Query 259 IEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVF 318
I RD +R +M + + I G+A + G L EGDE+L++NGI I+G E
Sbjct 601 IAGGRDC-----IRGQM-GIFVKTIFPNGSAAEDGRLKEGDEILDVNGIPIKGLTFQEAI 654
Query 319 DLLSDMHGTLTFVLIPSQQIKP 340
+ L + + ++ + P
Sbjct 655 HTFKQIRSGLFVLTVRTKLVSP 676
Score = 37.4 bits (85), Expect = 0.55, Method: Compositional matrix adjust.
Identities = 18/56 (32%), Positives = 32/56 (57%), Gaps = 0/56 (0%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+++++++ +GGAA + G L GDE+L ING + G E +L G + V+
Sbjct 360 AIVVTQVKEGGAAHRDGRLSLGDELLVINGHLLVGLSHEEAVAILRSATGMVQLVV 415
Score = 35.0 bits (79), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 20/74 (27%), Positives = 34/74 (46%), Gaps = 4/74 (5%)
Query 252 ETVKIVRIEKARDIPLGATVRNEMD----SVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
E V + + + LG +V D S+ + R+ GAA + G ++ GD +L +NG
Sbjct 2618 EDVCFIVLNRKEGSGLGFSVAGGTDVEPKSITVHRVFSQGAASQEGTMNRGDFLLSVNGA 2677
Query 308 EIRGKDVNEVFDLL 321
+ G V +L
Sbjct 2678 SLAGLAHGNVLKVL 2691
>sp|Q6DFV3|RHG21_MOUSE Rho GTPase-activating protein 21 OS=Mus
musculus OX=10090 GN=Arhgap21 PE=1 SV=2
Length=1945
Score = 43.1 bits (100), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 21/70 (30%), Positives = 40/70 (57%), Gaps = 4/70 (6%)
Query 268 GATVRNE---MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
G RN MD++ + ++ +GG A ++GL GD ++++NG + GK ++V L+ +
Sbjct 95 GGKQRNRLEPMDTIFVKQVKEGGPAFEAGLC-TGDRIIKVNGESVIGKTYSQVIALIQNS 153
Query 325 HGTLTFVLIP 334
TL ++P
Sbjct 154 DTTLELSVMP 163
>sp|Q9WVE9|ITSN1_RAT Intersectin-1 OS=Rattus norvegicus OX=10116
GN=Itsn1 PE=1 SV=2
Length=1713
Score = 43.1 bits (100), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 27/89 (30%), Positives = 40/89 (45%), Gaps = 18/89 (20%)
Query 320 LLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDIL 379
LLS +T +P ++P V V +DY +D L+F KG I+
Sbjct 1127 LLSPGTSKITPTELPKTAVQP-----AVCQVIGMYDYTAQNDDE-------LAFSKGQII 1174
Query 380 HVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+V+S+EDP+WW+ G GL P
Sbjct 1175 NVLSKEDPDWWKGEVSGQ------VGLFP 1197
>sp|Q925E1|SNTG1_MOUSE Gamma-1-syntrophin OS=Mus musculus OX=10090
GN=Sntg1 PE=2 SV=2
Length=517
Score = 42.4 bits (98), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 36/105 (34%), Positives = 50/105 (48%), Gaps = 11/105 (10%)
Query 220 LLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDS-- 277
L LA D + QE + ++ E Y G TV I R G +++ +
Sbjct 29 LHLARDLLMLQEQDVLCVSGEPFYS-----GERTVTIRRQTVG---GFGLSIKGGAEHNI 80
Query 278 -VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
V+IS+I K AE SGLL GD +L+INGI +R EV +L
Sbjct 81 PVVISKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVL 125
>sp|O55164|MPDZ_RAT Multiple PDZ domain protein OS=Rattus norvegicus
OX=10116 GN=Mpdz PE=1 SV=1
Length=2054
Score = 42.7 bits (99), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 24/59 (41%), Positives = 34/59 (58%), Gaps = 1/59 (2%)
Query 272 RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTF 330
RN+ V +S IVKGG A+ G L +GD++L +NG ++R V LL GT+T
Sbjct 1728 RNDT-GVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVTL 1785
Score = 42.0 bits (97), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 33/122 (27%), Positives = 60/122 (49%), Gaps = 3/122 (2%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
LG ++ + I ++ G SG L GDE+LE+NGI + G++ +V ++L ++
Sbjct 557 LGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGINLLGENHQDVVNILKELPI 616
Query 327 TLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQED 386
+T V ++ PP A V + H D + ++ P++ E S + D + +S D
Sbjct 617 DVTMVC--CRRTVPPTALSEVDSLDIH-DLELTEKPHIDLGEFIGSSETEDPMLAMSDVD 673
Query 387 PN 388
N
Sbjct 674 QN 675
Score = 39.3 bits (90), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 25/71 (35%), Positives = 38/71 (54%), Gaps = 8/71 (11%)
Query 251 GETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
G+T + I D LGA +II + + GAA K G L GD++LE+NGI++R
Sbjct 1619 GQTGLGLSIVGGSDTLLGA--------IIIHEVYEEGAACKDGRLWAGDQILEVNGIDLR 1670
Query 311 GKDVNEVFDLL 321
+E ++L
Sbjct 1671 KATHDEAINVL 1681
Score = 34.7 bits (78), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 6/95 (6%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
++I +V GG AEK G L GD ++ +N I + + E + L + + +
Sbjct 720 IVIRSLVPGGIAEKDGRLFPGDRLMFVNDINLENSTLEEAVEALKGAPSGMVRIGVA--- 776
Query 338 IKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLS 372
KP P +V A D P+ C+E+GLS
Sbjct 777 -KPLPLSPEEGYVSAKEDTFLC-SPHT-CKEMGLS 808
Score = 33.9 bits (76), Expect = 7.7, Method: Compositional matrix adjust.
Identities = 15/56 (27%), Positives = 29/56 (52%), Gaps = 0/56 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
+ + + GAA + G L GD+++ +NG + G E +L GT+T +++
Sbjct 1998 IYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVL 2053
>sp|O35430|APBA1_RAT Amyloid-beta A4 precursor protein-binding
family A member 1 OS=Rattus norvegicus OX=10116 GN=Apba1 PE=1
SV=1
Length=839
Score = 42.7 bits (99), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 25/65 (38%), Positives = 37/65 (57%), Gaps = 5/65 (8%)
Query 252 ETVKIVRIEKARDIPLGATVRNE-----MDSVIISRIVKGGAAEKSGLLHEGDEVLEING 306
E K V IEK + LG + + +VII+ ++ GG AEKSG L+ GD+++ ING
Sbjct 654 ENCKDVFIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSING 713
Query 307 IEIRG 311
+ G
Sbjct 714 TSLVG 718
>sp|B2RUJ5|APBA1_MOUSE Amyloid-beta A4 precursor protein-binding
family A member 1 OS=Mus musculus OX=10090 GN=Apba1 PE=1
SV=2
Length=842
Score = 42.7 bits (99), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 25/65 (38%), Positives = 37/65 (57%), Gaps = 5/65 (8%)
Query 252 ETVKIVRIEKARDIPLGATVRNE-----MDSVIISRIVKGGAAEKSGLLHEGDEVLEING 306
E K V IEK + LG + + +VII+ ++ GG AEKSG L+ GD+++ ING
Sbjct 657 ENCKDVFIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSING 716
Query 307 IEIRG 311
+ G
Sbjct 717 TSLVG 721
>sp|Q5T5U3|RHG21_HUMAN Rho GTPase-activating protein 21 OS=Homo
sapiens OX=9606 GN=ARHGAP21 PE=1 SV=2
Length=1958
Score = 42.7 bits (99), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 21/70 (30%), Positives = 40/70 (57%), Gaps = 4/70 (6%)
Query 268 GATVRNE---MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
G RN MD++ + ++ +GG A ++GL GD ++++NG + GK ++V L+ +
Sbjct 89 GGKQRNRLEPMDTIFVKQVKEGGPAFEAGLC-TGDRIIKVNGESVIGKTYSQVIALIQNS 147
Query 325 HGTLTFVLIP 334
TL ++P
Sbjct 148 DTTLELSVMP 157
>sp|Q02410|APBA1_HUMAN Amyloid-beta A4 precursor protein-binding
family A member 1 OS=Homo sapiens OX=9606 GN=APBA1 PE=1 SV=3
Length=837
Score = 42.7 bits (99), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 37/136 (27%), Positives = 61/136 (45%), Gaps = 20/136 (15%)
Query 252 ETVKIVRIEKARDIPLGATVRNE-----MDSVIISRIVKGGAAEKSGLLHEGDEVLEING 306
E K V IEK + LG + + +VII+ ++ GG AEKSG L+ GD+++ ING
Sbjct 652 ENCKDVFIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSING 711
Query 307 IEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPC 366
+ G ++ ++ + L ++ PP TV+ + Y
Sbjct 712 TSLVGLPLSTCQSIIKGLKNQSRVKL---NIVRCPPVT-TVLIRRPDLRY---------- 757
Query 367 RELGLSFQKGDILHVI 382
+LG S Q G I ++
Sbjct 758 -QLGFSVQNGIICSLM 772
>sp|Q9QZR8|PDZD2_RAT PDZ domain-containing protein 2 OS=Rattus
norvegicus OX=10116 GN=Pdzd2 PE=1 SV=1
Length=2766
Score = 42.7 bits (99), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 7/75 (9%)
Query 259 IEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVF 318
I RD +R +M + + I G+A + G L EGDE+L++NGI I+G E
Sbjct 550 IAGGRDC-----IRGQM-GIFVKTIFPNGSAAEDGRLKEGDEILDVNGIPIKGLTFQEAI 603
Query 319 DLLSDMHGTLTFVLI 333
+ L FVL
Sbjct 604 HTFKQIRSGL-FVLT 617
Score = 42.4 bits (98), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 17/34 (50%), Positives = 25/34 (74%), Gaps = 0/34 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
++I R+ KGGAAE++G + GDE+L ING + G
Sbjct 2705 LVIKRVYKGGAAERAGTIEAGDEILAINGKPLVG 2738
Score = 37.4 bits (85), Expect = 0.53, Method: Compositional matrix adjust.
Identities = 18/56 (32%), Positives = 32/56 (57%), Gaps = 0/56 (0%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+++++++ +GGAA + G L GDE+L ING + G E +L G + V+
Sbjct 360 AIVVTQVKEGGAAHRDGRLSLGDELLVINGHLLVGLSHEEAVAILRSATGMVQLVV 415
Score = 35.4 bits (80), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 4/74 (5%)
Query 252 ETVKIVRIEKARDIPLGATVRNEMD----SVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
E + + + K LG +V D SV++ R+ G A + G + GD +L +NG
Sbjct 2546 EDICFIVLNKKEGSGLGFSVAGGADVEPKSVMVHRVFSQGVASQEGTVSRGDFLLSVNGT 2605
Query 308 EIRGKDVNEVFDLL 321
+ G +EV +L
Sbjct 2606 SLAGLAHSEVTKVL 2619
>sp|Q69ZH9|RHG23_MOUSE Rho GTPase-activating protein 23 OS=Mus
musculus OX=10090 GN=Arhgap23 PE=1 SV=2
Length=1483
Score = 42.7 bits (99), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 19/60 (32%), Positives = 35/60 (58%), Gaps = 1/60 (2%)
Query 275 MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP 334
MD++ + + GG A ++GL GD ++++NG I GK ++V L+ + TL ++P
Sbjct 95 MDTIFVKNVKDGGPAHRAGL-RTGDRLVKVNGESIIGKTYSQVIGLIQNSDDTLELSIMP 153
>sp|F1MAD2|INADL_RAT InaD-like protein OS=Rattus norvegicus OX=10116
GN=Patj PE=1 SV=2
Length=1836
Score = 42.7 bits (99), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 30/90 (33%), Positives = 44/90 (49%), Gaps = 5/90 (6%)
Query 242 VYESIGQYGGET---VKIVRIEK--ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLH 296
+Y QY E V +V ++K R + L + V IS IVKGGAA+ G L
Sbjct 1553 IYRDEAQYRDEENLEVFLVDLQKKTGRGLGLSIVGKRSGSGVFISDIVKGGAADLDGRLI 1612
Query 297 EGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
GD++L +NG ++R V +L + G
Sbjct 1613 RGDQILSVNGEDVRQASQETVATILKCVQG 1642
Score = 40.8 bits (94), Expect = 0.058, Method: Compositional matrix adjust.
Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 5/70 (7%)
Query 256 IVRIEKARDIPLGATV----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
I+ I K R LG ++ +D+++I + + GAA + G L GD++LE+NG+++R
Sbjct 1474 IIEISKGRS-GLGLSIVGGKDTPLDAIVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRS 1532
Query 312 KDVNEVFDLL 321
E L
Sbjct 1533 SSHEEAITAL 1542
Score = 38.1 bits (87), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 19/52 (37%), Positives = 27/52 (52%), Gaps = 0/52 (0%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV 331
IS I GG + LL DE+LE+NG+++ GK E L ++ T V
Sbjct 585 ISSIAPGGPVDTLNLLQPEDELLEVNGVQLYGKSRREAVSFLKEVPPPFTLV 636
Score = 35.0 bits (79), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 29/122 (24%), Positives = 49/122 (40%), Gaps = 12/122 (10%)
Query 251 GETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
G T + I + G V + V++ IV GG A++ G L GD +L+I ++
Sbjct 244 GHTEDVELINDGSGLGFG-IVGGKSSGVVVRTIVPGGLADRDGRLQTGDHILKIGSTNVQ 302
Query 311 GKDVNEVFDLLSDMHGTLTFVLI--PSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRE 368
G +V +L + ++ ++ P +I P + V P V R
Sbjct 303 GMTSEQVAQVLRNCGNSVRMLVARDPVGEIAVTPPTPASLPVAL---------PVVATRT 353
Query 369 LG 370
LG
Sbjct 354 LG 355
>sp|O75970|MPDZ_HUMAN Multiple PDZ domain protein OS=Homo sapiens
OX=9606 GN=MPDZ PE=1 SV=2
Length=2070
Score = 42.7 bits (99), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 24/59 (41%), Positives = 34/59 (58%), Gaps = 1/59 (2%)
Query 272 RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTF 330
RN+ V +S IVKGG A+ G L +GD++L +NG ++R V LL GT+T
Sbjct 1744 RNDT-GVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVTL 1801
Score = 39.7 bits (91), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 27/76 (36%), Positives = 42/76 (55%), Gaps = 7/76 (9%)
Query 250 GGETVKIVRIEKARDIPLGATVRNEMDS----VIISRIVKGGAAEKSGLLHEGDEVLEIN 305
G ET + I K R LG ++ D+ +II + + GAA K G L GD++LE+N
Sbjct 1625 GCETT--IEISKGR-TGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVN 1681
Query 306 GIEIRGKDVNEVFDLL 321
GI++R +E ++L
Sbjct 1682 GIDLRKATHDEAINVL 1697
Score = 37.0 bits (84), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 26/103 (25%), Positives = 50/103 (49%), Gaps = 3/103 (3%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
LG ++ + I ++ G SG L GDE+LE+NGI + G++ +V ++L ++
Sbjct 565 LGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGITLLGENHQDVVNILKELPI 624
Query 327 TLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCREL 369
+T V + PP ++ + D + ++ P+V E
Sbjct 625 EVTMVCC---RRTVPPTTQSELDSLDLCDIELTEKPHVDLGEF 664
Score = 34.3 bits (77), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 24/112 (21%), Positives = 48/112 (43%), Gaps = 9/112 (8%)
Query 228 AEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDS------VIIS 281
A + +T +++ G K + +E+ D LG ++ S + +
Sbjct 1961 ASSSLSFTGLTSSSIFQD--DLGPPQCKSITLERGPD-GLGFSIVGGYGSPHGDLPIYVK 2017
Query 282 RIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
+ GAA + G L GD+++ +NG + G E +L GT+T +++
Sbjct 2018 TVFAKGAASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVL 2069
>sp|Q9PU36|PCLO_CHICK Protein piccolo (Fragment) OS=Gallus gallus
OX=9031 GN=PCLO PE=2 SV=1
Length=5120
Score = 42.7 bits (99), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 23/65 (35%), Positives = 40/65 (62%), Gaps = 4/65 (6%)
Query 257 VRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
+R+ ++IP + E+ I++++ GG AE++G L EG +VLE NGI + GK E
Sbjct 4433 IRVVGGKEIPGSS---GEI-GAYIAKVLPGGNAEQTGKLIEGMQVLEWNGIPLTGKTYEE 4488
Query 317 VFDLL 321
V +++
Sbjct 4489 VQNII 4493
>sp|Q63ZW7|INADL_MOUSE InaD-like protein OS=Mus musculus OX=10090
GN=Patj PE=1 SV=2
Length=1834
Score = 42.4 bits (98), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 31/92 (34%), Positives = 45/92 (49%), Gaps = 5/92 (5%)
Query 242 VYESIGQYGGET---VKIVRIEK--ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLH 296
VY QY E V +V ++K R + L + V IS IVKGGAA+ G L
Sbjct 1551 VYRDEAQYRDEENLEVFLVDLQKKTGRGLGLSIVGKRSGSGVFISDIVKGGAADLDGRLI 1610
Query 297 EGDEVLEINGIEIRGKDVNEVFDLLSDMHGTL 328
GD++L +NG ++R V +L + G +
Sbjct 1611 RGDQILSVNGEDMRHASQETVATILKCVQGLV 1642
Score = 40.4 bits (93), Expect = 0.060, Method: Compositional matrix adjust.
Identities = 22/70 (31%), Positives = 38/70 (54%), Gaps = 5/70 (7%)
Query 256 IVRIEKARDIPLGATV----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
I+ I K R LG ++ +D+++I + + GAA + G L GD++LE+NG+++R
Sbjct 1472 IIEISKGRS-GLGLSIVGGKDTPLDAIVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRS 1530
Query 312 KDVNEVFDLL 321
E L
Sbjct 1531 SSHEEAITAL 1540
Score = 38.1 bits (87), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 21/82 (26%), Positives = 40/82 (49%), Gaps = 1/82 (1%)
Query 251 GETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
G T ++ I + G V + V++ IV GG A++ G L GD +L+I G ++
Sbjct 244 GHTEEVELINDGSGLGFG-IVGGKSSGVVVRTIVPGGLADRDGRLQTGDHILKIGGTNVQ 302
Query 311 GKDVNEVFDLLSDMHGTLTFVL 332
G +V +L + ++ ++
Sbjct 303 GMTSEQVAQVLRNCGNSVRMLV 324
Score = 36.6 bits (83), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 18/52 (35%), Positives = 27/52 (52%), Gaps = 0/52 (0%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV 331
IS + GG + LL DE+LE+NG+++ GK E L ++ T V
Sbjct 585 ISSVAPGGPVDTLNLLQPEDELLEVNGMQLYGKSRREAVSFLKEVPPPFTLV 636
>sp|Q3UHD6|SNX27_MOUSE Sorting nexin-27 OS=Mus musculus OX=10090
GN=Snx27 PE=1 SV=2
Length=539
Score = 42.0 bits (97), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 28/94 (30%), Positives = 46/94 (49%), Gaps = 20/94 (21%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
+S ++ GGAA+++G+ +GD +LE+NG+ + G +V DL+ L ++
Sbjct 79 VSAVLPGGAADRAGV-RKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSV---- 133
Query 340 PPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSF 373
PP + + DPSDD LG SF
Sbjct 134 PPHEADNL---------DPSDD------SLGQSF 152
>sp|Q8NI35|INADL_HUMAN InaD-like protein OS=Homo sapiens OX=9606
GN=PATJ PE=1 SV=3
Length=1801
Score = 42.4 bits (98), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 40/145 (28%), Positives = 64/145 (44%), Gaps = 24/145 (17%)
Query 186 AQDLAQEVQTV-LKPVHHKEGQELTALLNTPHIQALLLAHDKV---AEQEMQLEPITDER 241
A D EV V L+ H+E +TAL TP L++ D+ E+ +++ P+ ++
Sbjct 1481 AGDQILEVNGVDLRNSSHEEA--ITALRQTPQKVRLVVYRDEAHYRDEENLEIFPVDLQK 1538
Query 242 VYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEV 301
+ R + L + V IS IVKGGAA+ G L +GD++
Sbjct 1539 ------------------KAGRGLGLSIVGKRNGSGVFISDIVKGGAADLDGRLIQGDQI 1580
Query 302 LEINGIEIRGKDVNEVFDLLSDMHG 326
L +NG ++R V +L G
Sbjct 1581 LSVNGEDMRNASQETVATILKCAQG 1605
Score = 41.2 bits (95), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 21/52 (40%), Positives = 29/52 (56%), Gaps = 0/52 (0%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV 331
IS IV GG + GLL DE+LE+NG+++ GK E L ++ T V
Sbjct 583 ISSIVSGGPVDTLGLLQPEDELLEVNGMQLYGKSRREAVSFLKEVPPPFTLV 634
Score = 38.9 bits (89), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 22/70 (31%), Positives = 37/70 (53%), Gaps = 5/70 (7%)
Query 256 IVRIEKARDIPLGATVRNEMDS----VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
I+ I K R LG ++ D+ ++I + + GAA + G L GD++LE+NG+++R
Sbjct 1437 IIEISKGRS-GLGLSIVGGKDTPLNAIVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRN 1495
Query 312 KDVNEVFDLL 321
E L
Sbjct 1496 SSHEEAITAL 1505
Score = 37.7 bits (86), Expect = 0.45, Method: Compositional matrix adjust.
Identities = 28/127 (22%), Positives = 56/127 (44%), Gaps = 3/127 (2%)
Query 206 QELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDI 265
Q + L T L++A + V + + D + E++ G ++ I +
Sbjct 201 QAIALLQQTTGSLRLIVAREPVHTKSSTSSSLNDTTLPETV--CWGHVEEVELINDGSGL 258
Query 266 PLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMH 325
G V + V++ IV GG A++ G L GD +L+I G ++G +V +L +
Sbjct 259 GFG-IVGGKTSGVVVRTIVPGGLADRDGRLQTGDHILKIGGTNVQGMTSEQVAQVLRNCG 317
Query 326 GTLTFVL 332
++ ++
Sbjct 318 NSVRMLV 324
Score = 33.9 bits (76), Expect = 7.0, Method: Compositional matrix adjust.
Identities = 22/111 (20%), Positives = 53/111 (48%), Gaps = 15/111 (14%)
Query 255 KIVRIEKARDIPLGATVRN------------EMDSVIISRIVKGGAAEKSGLLHEGDEVL 302
+IV I + ++ LG ++ E+ + I ++++ A K+ L GD++L
Sbjct 1067 RIVEIFREPNVSLGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTNALKTGDKIL 1126
Query 303 EINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAH 353
E++G++++ +E + + + + F++ Q + P +H KA+
Sbjct 1127 EVSGVDLQNASHSEAVEAIKNAGNPVVFIV---QSLSSTPRVIPNVHNKAN 1174
Score = 33.5 bits (75), Expect = 9.5, Method: Compositional matrix adjust.
Identities = 23/88 (26%), Positives = 38/88 (43%), Gaps = 6/88 (7%)
Query 257 VRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
+ I R PLG V I+ I G A ++ L GD ++ ING + G +
Sbjct 1689 ISIAGGRGSPLGDI------PVFIAMIQASGVAARTQKLKVGDRIVSINGQPLDGLSHAD 1742
Query 317 VFDLLSDMHGTLTFVLIPSQQIKPPPAK 344
V +LL + +G + ++ I A+
Sbjct 1743 VVNLLKNAYGRIILQVVADTNISAIAAQ 1770
>sp|Q8K4V4|SNX27_RAT Sorting nexin-27 OS=Rattus norvegicus OX=10116
GN=Snx27 PE=1 SV=2
Length=539
Score = 42.0 bits (97), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 28/94 (30%), Positives = 46/94 (49%), Gaps = 20/94 (21%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
+S ++ GGAA+++G+ +GD +LE+NG+ + G +V DL+ L ++
Sbjct 79 VSAVLPGGAADRAGV-RKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSV---- 133
Query 340 PPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSF 373
PP + + DPSDD LG SF
Sbjct 134 PPHEADNL---------DPSDD------SLGQSF 152
>sp|A5PKA5|SNX27_BOVIN Sorting nexin-27 OS=Bos taurus OX=9913
GN=SNX27 PE=2 SV=1
Length=541
Score = 42.0 bits (97), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 28/94 (30%), Positives = 46/94 (49%), Gaps = 20/94 (21%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
+S ++ GGAA+++G+ +GD +LE+NG+ + G +V DL+ L ++
Sbjct 81 VSAVLPGGAADRAGV-RKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSV---- 135
Query 340 PPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSF 373
PP + + DPSDD LG SF
Sbjct 136 PPHEADNL---------DPSDD------SLGQSF 154
>sp|Q9Y6N9|USH1C_HUMAN Harmonin OS=Homo sapiens OX=9606 GN=USH1C
PE=1 SV=3
Length=552
Score = 42.0 bits (97), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 22/61 (36%), Positives = 40/61 (66%), Gaps = 2/61 (3%)
Query 248 QYGGETVKIVRIEK--ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
Q G+ V+++RI+K + D+ L V + + V++S + + GAAE+ G + +GDE++ IN
Sbjct 447 QIMGKDVRLLRIKKEGSLDLALEGGVDSPIGKVVVSAVYERGAAERHGGIVKGDEIMAIN 506
Query 306 G 306
G
Sbjct 507 G 507
Score = 39.7 bits (91), Expect = 0.10, Method: Compositional matrix adjust.
Identities = 28/91 (31%), Positives = 47/91 (52%), Gaps = 4/91 (4%)
Query 234 LEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAE 290
L P+ + Y+ + +K VR+++ LG +VR ++ + IS ++KGG A+
Sbjct 65 LIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKGGQAD 124
Query 291 KSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
GL GDE++ ING I EV +L+
Sbjct 125 SVGL-QVGDEIVRINGYSISSCTHEEVINLI 154
>sp|Q9Z0R6|ITSN2_MOUSE Intersectin-2 OS=Mus musculus OX=10090
GN=Itsn2 PE=1 SV=2
Length=1659
Score = 42.0 bits (97), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 28/97 (29%), Positives = 43/97 (44%), Gaps = 25/97 (26%)
Query 342 PAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQ 401
P V V A +DY ++ E L+F KG +++V++++DP+WWQ G
Sbjct 1085 PTFHAVCQVIAMYDYMANN-------EDELNFSKGQLINVMNKDDPDWWQGETNG----- 1132
Query 402 PLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCA 438
L GL P +K T + D + WCA
Sbjct 1133 -LTGLFPSN-------YVKMTTDSDPSQQ-----WCA 1156
>sp|P29476|NOS1_RAT Nitric oxide synthase 1 OS=Rattus norvegicus
OX=10116 GN=Nos1 PE=1 SV=1
Length=1429
Score = 42.0 bits (97), Expect = 0.025, Method: Compositional matrix adjust.
Identities = 26/79 (33%), Positives = 42/79 (53%), Gaps = 2/79 (3%)
Query 257 VRIEKARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
VR+ K + LG V+ + VIIS +++GGAAE+SGL+ GD +L +N +
Sbjct 18 VRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVNDRPLVDLSY 77
Query 315 NEVFDLLSDMHGTLTFVLI 333
+ ++L + VLI
Sbjct 78 DSALEVLRGIASETHVVLI 96
>sp|Q9Z0J4|NOS1_MOUSE Nitric oxide synthase 1 OS=Mus musculus
OX=10090 GN=Nos1 PE=1 SV=1
Length=1429
Score = 41.6 bits (96), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 26/79 (33%), Positives = 42/79 (53%), Gaps = 2/79 (3%)
Query 257 VRIEKARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
VR+ K + LG V+ + VIIS +++GGAAE+SGL+ GD +L +N +
Sbjct 18 VRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVNDRPLVDLSY 77
Query 315 NEVFDLLSDMHGTLTFVLI 333
+ ++L + VLI
Sbjct 78 DSALEVLRGIASETHVVLI 96
>sp|Q9NSN8|SNTG1_HUMAN Gamma-1-syntrophin OS=Homo sapiens OX=9606
GN=SNTG1 PE=1 SV=1
Length=517
Score = 41.2 bits (95), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 35/105 (33%), Positives = 50/105 (48%), Gaps = 11/105 (10%)
Query 220 LLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDS-- 277
L LA D + QE + ++ E Y G TV I R G +++ +
Sbjct 29 LHLAKDILMIQEQDVICVSGEPFYS-----GERTVTIRRQTVG---GFGLSIKGGAEHNI 80
Query 278 -VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
V++S+I K AE SGLL GD +L+INGI +R EV +L
Sbjct 81 PVVVSKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVL 125
>sp|Q9ULJ8|NEB1_HUMAN Neurabin-1 OS=Homo sapiens OX=9606 GN=PPP1R9A
PE=1 SV=2
Length=1098
Score = 41.6 bits (96), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 18/68 (26%), Positives = 37/68 (54%), Gaps = 0/68 (0%)
Query 265 IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
+ +GA E + + + +GGAA++ G + D+++E++GI + G N +L +
Sbjct 521 MGVGADAGLEKLGIFVKTVTEGGAAQRDGRIQVNDQIVEVDGISLVGVTQNFAATVLRNT 580
Query 325 HGTLTFVL 332
G + FV+
Sbjct 581 KGNVRFVI 588
>sp|Q9NY99|SNTG2_HUMAN Gamma-2-syntrophin OS=Homo sapiens OX=9606
GN=SNTG2 PE=1 SV=2
Length=539
Score = 41.2 bits (95), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 28/100 (28%), Positives = 51/100 (51%), Gaps = 6/100 (6%)
Query 247 GQYGGETVKIVRIEKARDIPLGATVRNEMDS---VIISRIVKGGAAEKSGLLHEGDEVLE 303
G + G + V + + LG +++ + V+IS+I + AA+++G+L GD VL+
Sbjct 64 GSHQGRNRRTVTLRRQPVGGLGLSIKGGSEHNVPVVISKIFEDQAADQTGMLFVGDAVLQ 123
Query 304 INGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPA 343
+NGI + EV LL + +T I + ++ PA
Sbjct 124 VNGIHVENATHEEVVHLLRNAGDEVT---ITVEYLREAPA 160
>sp|O35867|NEB1_RAT Neurabin-1 OS=Rattus norvegicus OX=10116 GN=Ppp1r9a
PE=1 SV=1
Length=1095
Score = 41.6 bits (96), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 18/66 (27%), Positives = 36/66 (55%), Gaps = 0/66 (0%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
+GA E + + + +GGAA++ G + D+++E++GI + G N +L + G
Sbjct 524 VGADAGLEKLGIFVKTVTEGGAAQRDGRIQVNDQIVEVDGISLVGVTQNFAATVLRNTKG 583
Query 327 TLTFVL 332
+ FV+
Sbjct 584 NVRFVI 589
>sp|P29355|SEM5_CAEEL Sex muscle abnormal protein 5 OS=Caenorhabditis
elegans OX=6239 GN=sem-5 PE=1 SV=1
Length=228
Score = 40.0 bits (92), Expect = 0.034, Method: Compositional matrix adjust.
Identities = 17/44 (39%), Positives = 31/44 (70%), Gaps = 9/44 (20%)
Query 350 VKAHFDYDPSDDPYVPCRELG-LSFQKGDILHVISQEDPNWWQA 392
V+A FD++P +E G L+F++GD++ +I+++DPNWW+
Sbjct 159 VQALFDFNP--------QESGELAFKRGDVITLINKDDPNWWEG 194
>sp|Q9Z0R4|ITSN1_MOUSE Intersectin-1 OS=Mus musculus OX=10090
GN=Itsn1 PE=1 SV=2
Length=1714
Score = 41.2 bits (95), Expect = 0.034, Method: Compositional matrix adjust.
Identities = 26/89 (29%), Positives = 40/89 (45%), Gaps = 18/89 (20%)
Query 320 LLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDIL 379
LLS +T +P ++P V V +DY +D L+F KG I+
Sbjct 1128 LLSPGTSKITPTELPKTAVQP-----AVCQVIGMYDYTAQNDDE-------LAFSKGQII 1175
Query 380 HVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+V+++EDP+WW+ G GL P
Sbjct 1176 NVLNKEDPDWWKGEVSGQ------VGLFP 1198
>sp|E2QYC9|INADL_CANLF InaD-like protein OS=Canis lupus familiaris
OX=9615 GN=PATJ PE=1 SV=3
Length=1828
Score = 41.2 bits (95), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 22/65 (34%), Positives = 34/65 (52%), Gaps = 8/65 (12%)
Query 257 VRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
+ I RD PL D+++I + + GAA + G L GD++LE+NGI++R E
Sbjct 1476 LSIVGGRDTPL--------DAIVIHEVYEEGAAARDGRLWAGDQILEVNGIDLRSASHEE 1527
Query 317 VFDLL 321
L
Sbjct 1528 AITAL 1532
Score = 38.9 bits (89), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 38/145 (26%), Positives = 63/145 (43%), Gaps = 24/145 (17%)
Query 186 AQDLAQEVQTV-LKPVHHKEGQELTALLNTPHIQALLLAHDKV---AEQEMQLEPITDER 241
A D EV + L+ H+E +TAL TP L++ D+ E+ +++ P+ ++
Sbjct 1508 AGDQILEVNGIDLRSASHEEA--ITALRQTPQKVRLVVYRDEAHYRDEENLEIFPVDLQK 1565
Query 242 VYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEV 301
+ R + L + V IS IVKGGAA+ L +GD++
Sbjct 1566 ------------------KAGRGLGLSIVGKRNGSGVFISDIVKGGAADLDRRLIQGDQI 1607
Query 302 LEINGIEIRGKDVNEVFDLLSDMHG 326
L +NG ++R V +L G
Sbjct 1608 LSVNGEDMRNASQETVATVLKCAQG 1632
Score = 38.9 bits (89), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 22/97 (23%), Positives = 44/97 (45%), Gaps = 4/97 (4%)
Query 269 ATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTL 328
V + V++ IV GG A++ G L GD +L+I +++G +V +L + ++
Sbjct 261 GIVGGKSSGVVVRTIVPGGLADRDGRLQTGDHILKIGDTDVQGMTSEQVAQVLRNCGNSV 320
Query 329 TFVL----IPSQQIKPPPAKETVIHVKAHFDYDPSDD 361
++ + + PP + + A + PS D
Sbjct 321 RMLVARDPVGETSVTPPTPAALPVALPAVANRSPSTD 357
Score = 37.4 bits (85), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 19/52 (37%), Positives = 27/52 (52%), Gaps = 0/52 (0%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV 331
IS I GG + LL DE+LE+NG+++ GK E L ++ T V
Sbjct 583 ISSIAPGGPVDALNLLQPEDELLEVNGVQLYGKSRREAVSFLKEVPPPFTLV 634
Score = 34.7 bits (78), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 23/111 (21%), Positives = 52/111 (47%), Gaps = 15/111 (14%)
Query 255 KIVRIEKARDIPLGATVRN------------EMDSVIISRIVKGGAAEKSGLLHEGDEVL 302
+IV I + ++ LG ++ E+ + I ++++ A K+ L GD++L
Sbjct 1069 RIVEIFREPNVSLGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTNALKTGDKIL 1128
Query 303 EINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAH 353
E++G++++ E + + + + FV+ Q + P +H KA+
Sbjct 1129 EVSGVDLQNASHREAVEAIKNAGNPVVFVV---QSLSSTPRVIPSVHNKAN 1176
Score = 33.9 bits (76), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 28/110 (25%), Positives = 46/110 (42%), Gaps = 15/110 (14%)
Query 238 TDERVYESIGQYGGETVKIVR---------IEKARDIPLGATVRNEMDSVIISRIVKGGA 288
TD + S G TV+I+R I + PLG + I+ I G
Sbjct 1688 TDPSLKSSGMDMGPRTVEIIRELSDALGISIAGGKGSPLGDI------PIFIAMIQASGV 1741
Query 289 AEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
A ++ L GD ++ ING + G +V +LL + +G + ++ I
Sbjct 1742 AARTQKLKVGDRIVSINGQPLDGLSHADVVNLLKNAYGRIILQVVADTNI 1791
>sp|Q9HD26|GOPC_HUMAN Golgi-associated PDZ and coiled-coil motif-containing
protein OS=Homo sapiens OX=9606 GN=GOPC PE=1 SV=1
Length=462
Score = 40.4 bits (93), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 19/56 (34%), Positives = 31/56 (55%), Gaps = 0/56 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
++IS I G A++ G LH GD +L +NG+ +R E +LS G + F ++
Sbjct 313 ILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVV 368
>sp|Q8BH60|GOPC_MOUSE Golgi-associated PDZ and coiled-coil motif-containing
protein OS=Mus musculus OX=10090 GN=Gopc PE=1
SV=1
Length=463
Score = 40.4 bits (93), Expect = 0.053, Method: Compositional matrix adjust.
Identities = 19/56 (34%), Positives = 31/56 (55%), Gaps = 0/56 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
++IS I G A++ G LH GD +L +NG+ +R E +LS G + F ++
Sbjct 314 ILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVV 369
>sp|P98084|APBA2_MOUSE Amyloid-beta A4 precursor protein-binding
family A member 2 OS=Mus musculus OX=10090 GN=Apba2 PE=1
SV=2
Length=750
Score = 40.4 bits (93), Expect = 0.063, Method: Compositional matrix adjust.
Identities = 77/340 (23%), Positives = 131/340 (39%), Gaps = 72/340 (21%)
Query 40 PGDLGTRMMPIRRSAQLERIRQQQEDMRRRREEEGKKQELDLNSSM------RLKKLAQI 93
PGDL R + + ER + QE + E+ K+Q DLN KK+A
Sbjct 294 PGDL-QRGLKTKTRTPEERPKWPQEQVCNGLEQPRKQQRSDLNGPTDNNNIPETKKVASF 352
Query 94 PPKTGIDNPMF--DTEEGIVLES-------------PHYAVKILEIEDLFSSLKHIQ--- 135
P + P D +GI+ + P +++++ ++ S +K +Q
Sbjct 353 PSFVAVPGPCEAEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAA 412
Query 136 ------HTLVDSQSQEDISLLLQL----VQNKDFQNAFKIH-----------NAITVHMN 174
++ D+Q+ ++ L + V N D Q H I V M
Sbjct 413 KIKKKANSEGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMA 472
Query 175 KASPPFPLISNAQDL------AQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVA 228
+ P S +QD AQE + K + H E L+ QA +A+ +
Sbjct 473 RRRMPR---SASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFL 529
Query 229 ----------EQEMQLEPITDERVYES--IGQYGGETVKIVRIEKARDIPLGATVRNE-- 274
Q+ + I + +Y I E K +++EK + LG V
Sbjct 530 RANGINPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGW 589
Query 275 ---MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
+ +VI++ ++ GG A +SG L GD+++ ING + G
Sbjct 590 GSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVG 629
>sp|Q99767|APBA2_HUMAN Amyloid-beta A4 precursor protein-binding
family A member 2 OS=Homo sapiens OX=9606 GN=APBA2 PE=1 SV=3
Length=749
Score = 40.4 bits (93), Expect = 0.065, Method: Compositional matrix adjust.
Identities = 76/340 (22%), Positives = 132/340 (39%), Gaps = 72/340 (21%)
Query 40 PGDLGTRMMPIRRSAQLERIRQQQEDMRRRREEEGKKQELDLNSSM------RLKKLAQI 93
PGD P R+ + ER++ E + E+ K+Q DLN + KK+A
Sbjct 293 PGDPQRGFKPKTRTPE-ERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASF 351
Query 94 PPKTGIDNPMF--DTEEGIVLES-------------PHYAVKILEIEDLFSSLKHIQ--- 135
P + P D +GI+ + P +++++ ++ S +K +Q
Sbjct 352 PSFVAVPGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAA 411
Query 136 ------HTLVDSQSQEDISLLLQL----VQNKDFQNAFKIH-----------NAITVHMN 174
++ D+Q+ ++ L + V N D Q H I V M
Sbjct 412 KIKKKANSEGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMA 471
Query 175 KASPPFPLISNAQDL------AQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVA 228
+ P S +QD AQE + K + H E L+ QA +A+ +
Sbjct 472 RRRMPR---SASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFL 528
Query 229 ----------EQEMQLEPITDERVYES--IGQYGGETVKIVRIEKARDIPLGATVRNE-- 274
Q+ + I + +Y I E K +++EK + LG V
Sbjct 529 RANGINPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGW 588
Query 275 ---MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
+ +VI++ ++ GG A +SG L GD+++ ING + G
Sbjct 589 GSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVG 628
>sp|Q12923|PTN13_HUMAN Tyrosine-protein phosphatase non-receptor
type 13 OS=Homo sapiens OX=9606 GN=PTPN13 PE=1 SV=2
Length=2485
Score = 40.0 bits (92), Expect = 0.082, Method: Compositional matrix adjust.
Identities = 28/99 (28%), Positives = 50/99 (51%), Gaps = 10/99 (10%)
Query 256 IVRIEKAR-DIPLGATVRNEMDS------VIISRIVKGGAAEKSGLLHEGDEVLEINGIE 308
I +E A+ D LG +V +++ + + ++ GAAE G +H+GD VL +NG+
Sbjct 1366 IFEVELAKNDNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVS 1425
Query 309 IRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV 347
+ G + + L + G + +L+ Q P +KE V
Sbjct 1426 LEGATHKQAVETLRNT-GQVVHLLLEKGQ--SPTSKEHV 1461
Score = 35.8 bits (81), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 25/101 (25%), Positives = 47/101 (47%), Gaps = 12/101 (12%)
Query 251 GETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
G +I+ EK + LG + IS + GG A+ G L GD ++ +N + +
Sbjct 1103 GLGFQIIGGEKMGRLDLG---------IFISSVAPGGPADLDGCLKPGDRLISVNSVSLE 1153
Query 311 GKDVNEVFDLLSDMHGTLTFVLI-PSQQIKPPPAKETVIHV 350
G + ++L + +T V+ P ++I P+ T +H+
Sbjct 1154 GVSHHAAIEILQNAPEDVTLVISQPKEKISKVPS--TPVHL 1192
Score = 34.7 bits (78), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 21/68 (31%), Positives = 36/68 (53%), Gaps = 9/68 (13%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTL--TFVLIPS 335
V + ++ G A +SG + GD +L++NG ++G EV +S + GT F+L+
Sbjct 1531 VRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEV---ISALRGTAPEVFLLL-- 1585
Query 336 QQIKPPPA 343
+PPP
Sbjct 1586 --CRPPPG 1591
>sp|Q8VBX6|MPDZ_MOUSE Multiple PDZ domain protein OS=Mus musculus
OX=10090 GN=Mpdz PE=1 SV=2
Length=2055
Score = 40.0 bits (92), Expect = 0.083, Method: Compositional matrix adjust.
Identities = 23/59 (39%), Positives = 33/59 (56%), Gaps = 1/59 (2%)
Query 272 RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTF 330
RN+ V +S IVKGG A+ G L +GD++L +NG ++R V LL G +T
Sbjct 1729 RNDT-GVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRHATQEAVAALLKCSLGAVTL 1786
Score = 39.3 bits (90), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 25/71 (35%), Positives = 38/71 (54%), Gaps = 8/71 (11%)
Query 251 GETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
G+T + I D LGA +II + + GAA K G L GD++LE+NGI++R
Sbjct 1620 GQTGLGLSIVGGSDTLLGA--------IIIHEVYEEGAACKDGRLWAGDQILEVNGIDLR 1671
Query 311 GKDVNEVFDLL 321
+E ++L
Sbjct 1672 KATHDEAINVL 1682
Score = 37.0 bits (84), Expect = 0.74, Method: Compositional matrix adjust.
Identities = 31/122 (25%), Positives = 60/122 (49%), Gaps = 3/122 (2%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
LG ++ + I ++ G SG L GDE+LE+NGI + G++ +V ++L ++
Sbjct 558 LGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGINLLGENHQDVVNILKELPI 617
Query 327 TLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQED 386
+T V ++ PP A + + + D + ++ P++ E S + D + +S D
Sbjct 618 DVTMVC--CRRTVPPIALSEMDSLDIN-DLELTEKPHIDLGEFIGSSETEDPMLAMSDVD 674
Query 387 PN 388
N
Sbjct 675 QN 676
Score = 33.9 bits (76), Expect = 7.6, Method: Compositional matrix adjust.
Identities = 15/56 (27%), Positives = 29/56 (52%), Gaps = 0/56 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
+ + + GAA + G L GD+++ +NG + G E +L GT+T +++
Sbjct 1999 IYVKTVFAKGAAAEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVL 2054
>sp|Q9V9S7|SYDE_DROME Rho GTPase-activating protein 100F OS=Drosophila
melanogaster OX=7227 GN=RhoGAP100F PE=1 SV=2
Length=1866
Score = 40.0 bits (92), Expect = 0.090, Method: Compositional matrix adjust.
Identities = 25/75 (33%), Positives = 39/75 (52%), Gaps = 5/75 (7%)
Query 253 TVKIVRIEKARDIPLGATVR-----NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
TV++V I K LG +R + D V ISRI A SG L GDE+L +N +
Sbjct 176 TVQLVEIVKRPGQTLGLYIREGNGADRTDGVFISRIALESAVYNSGCLRVGDEILAVNLV 235
Query 308 EIRGKDVNEVFDLLS 322
++ +++V ++S
Sbjct 236 DVTHMSLDDVVIIMS 250
>sp|P0CY30|SEC4_CANAX Ras-related protein SEC4 OS=Candida albicans
OX=5476 GN=SEC4 PE=3 SV=1
Length=210
Score = 38.5 bits (88), Expect = 0.098, Method: Compositional matrix adjust.
Identities = 38/146 (26%), Positives = 63/146 (43%), Gaps = 12/146 (8%)
Query 101 NPMFDTEEGI-----VLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQ 155
NP F T GI +ES +K L++ D + T + I L+ +
Sbjct 40 NPSFITTIGIDFKIRTIESKGKRIK-LQVWDTAGQERFRTITTAYYRGAMGIVLIYDVTD 98
Query 156 NKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTP 215
++ F+N +T H N+ + F L+ N D V + V ++GQEL A LN P
Sbjct 99 SRSFENVENWFQTVTQHANEDAQIF-LVGNKCD-----DEVNRQVSKEQGQELAAKLNVP 152
Query 216 HIQALLLAHDKVAEQEMQLEPITDER 241
++A +++ V +L I E+
Sbjct 153 FLEASAKSNENVDSIFYELASIIQEK 178
>sp|C4YL11|SEC4_CANAW Ras-related protein SEC4 OS=Candida albicans
(strain WO-1) OX=294748 GN=SEC4 PE=3 SV=1
Length=210
Score = 38.5 bits (88), Expect = 0.098, Method: Compositional matrix adjust.
Identities = 38/146 (26%), Positives = 63/146 (43%), Gaps = 12/146 (8%)
Query 101 NPMFDTEEGI-----VLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQ 155
NP F T GI +ES +K L++ D + T + I L+ +
Sbjct 40 NPSFITTIGIDFKIRTIESKGKRIK-LQVWDTAGQERFRTITTAYYRGAMGIVLIYDVTD 98
Query 156 NKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTP 215
++ F+N +T H N+ + F L+ N D V + V ++GQEL A LN P
Sbjct 99 SRSFENVENWFQTVTQHANEDAQIF-LVGNKCD-----DEVNRQVSKEQGQELAAKLNVP 152
Query 216 HIQALLLAHDKVAEQEMQLEPITDER 241
++A +++ V +L I E+
Sbjct 153 FLEASAKSNENVDSIFYELASIIQEK 178
>sp|P0CY31|SEC4_CANAL Ras-related protein SEC4 OS=Candida albicans
(strain SC5314 / ATCC MYA-2876) OX=237561 GN=SEC4 PE=1
SV=1
Length=210
Score = 38.5 bits (88), Expect = 0.098, Method: Compositional matrix adjust.
Identities = 38/146 (26%), Positives = 63/146 (43%), Gaps = 12/146 (8%)
Query 101 NPMFDTEEGI-----VLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQ 155
NP F T GI +ES +K L++ D + T + I L+ +
Sbjct 40 NPSFITTIGIDFKIRTIESKGKRIK-LQVWDTAGQERFRTITTAYYRGAMGIVLIYDVTD 98
Query 156 NKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTP 215
++ F+N +T H N+ + F L+ N D V + V ++GQEL A LN P
Sbjct 99 SRSFENVENWFQTVTQHANEDAQIF-LVGNKCD-----DEVNRQVSKEQGQELAAKLNVP 152
Query 216 HIQALLLAHDKVAEQEMQLEPITDER 241
++A +++ V +L I E+
Sbjct 153 FLEASAKSNENVDSIFYELASIIQEK 178
>sp|Q4WHP5|HSE1_ASPFU Class E vacuolar protein-sorting machinery
protein hse1 OS=Aspergillus fumigatus (strain ATCC MYA-4609
/ CBS 101355 / FGSC A1100 / Af293) OX=330879 GN=hse1 PE=3
SV=1
Length=584
Score = 39.7 bits (91), Expect = 0.10, Method: Compositional matrix adjust.
Identities = 49/167 (29%), Positives = 79/167 (47%), Gaps = 26/167 (16%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELG-LSFQKGDILHVISQEDPNWWQAY 393
SQ + P + TV V+A FD+ PS E G L F+KGDI+ V+ +WW+
Sbjct 186 SQAVPPGTSAATVSRVRALFDFQPS--------EPGELQFRKGDIIAVLESVYKDWWKGS 237
Query 394 REGDEDNQPLAGLVPGKSFQQQREAMKQTIEE-DKEPEKSGKLWCAKKNKKKRKKVLYN- 451
G G+ P ++ + T+EE +E + +++ KN +K +L
Sbjct 238 LRGQ------TGIFPLNYVEKLPDP---TVEELQREAQMEAEVFGQIKNVEKLLTLLSTR 288
Query 452 ANKNDDYDNEEILTYEEMSLYHQPAN-RKRPIILIGPQNCGQNELRQ 497
+++ + DNEEI SLYH + R + I LIG + ++E Q
Sbjct 289 SSELNVQDNEEI-----TSLYHSTLSIRPKLIELIGKYSQKKDEFTQ 330
>sp|Q7ZYG4|OSTF1_XENLA Osteoclast-stimulating factor 1 OS=Xenopus
laevis OX=8355 GN=ostf1 PE=2 SV=1
Length=214
Score = 38.5 bits (88), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 17/55 (31%), Positives = 28/55 (51%), Gaps = 6/55 (11%)
Query 371 LSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEE 425
L F++GDIL++ D NWW+ +G GL+P +Q E++ + E
Sbjct 31 LYFEEGDILYIADMSDTNWWKGTCKGK------TGLIPSNYVAEQAESIDNPLHE 79
>sp|E9Q9W7|PDZD7_MOUSE PDZ domain-containing protein 7 OS=Mus
musculus OX=10090 GN=Pdzd7 PE=1 SV=2
Length=1021
Score = 39.7 bits (91), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 21/74 (28%), Positives = 42/74 (57%), Gaps = 4/74 (5%)
Query 252 ETVKIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEINGIE 308
+ + VR+EK+ LG +VR + + +S++ +G +AE++GL GD++ E+NG+
Sbjct 82 DIIHAVRVEKSPSGRLGFSVRGGSEHGLGIFVSKVEEGSSAERAGLC-VGDKITEVNGLS 140
Query 309 IRGKDVNEVFDLLS 322
+ + LL+
Sbjct 141 LESTTMGSAVRLLT 154
>sp|Q9CX99|GRAP_MOUSE GRB2-related adapter protein OS=Mus musculus
OX=10090 GN=Grap PE=1 SV=1
Length=217
Score = 38.1 bits (87), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 40/138 (29%), Positives = 64/138 (46%), Gaps = 25/138 (18%)
Query 272 RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI-EIRGKDV--NEVFDLLS---DMH 325
RN + + +I R + E S ++ GD+V + E GK E F+ L+ D +
Sbjct 77 RNHLGAFLI-RESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEEKFNSLNELVDFY 135
Query 326 GTLTF-----VLIPSQQ--IKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDI 378
T T + + +Q IKP A +A FD+ D P + LS ++GDI
Sbjct 136 RTTTIAKRRQIFLCDEQPLIKPSRA----CFAQAQFDFSAQD----PSQ---LSLRRGDI 184
Query 379 LHVISQEDPNWWQAYREG 396
+ V+ +EDP+WW+ G
Sbjct 185 VEVVEREDPHWWRGRAGG 202
>sp|A6QLK6|GRAP_BOVIN GRB2-related adapter protein OS=Bos taurus
OX=9913 GN=GRAP PE=2 SV=1
Length=217
Score = 38.1 bits (87), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 19/58 (33%), Positives = 30/58 (52%), Gaps = 7/58 (12%)
Query 339 KPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREG 396
+P P +A FD+ D P + LSF++GDI+ V+ + DP+WW+ G
Sbjct 152 EPLPKPPRACFAQAQFDFSAQD----PSQ---LSFRRGDIIEVLERLDPSWWRGRLSG 202
>sp|Q64512|PTN13_MOUSE Tyrosine-protein phosphatase non-receptor
type 13 OS=Mus musculus OX=10090 GN=Ptpn13 PE=1 SV=2
Length=2453
Score = 39.3 bits (90), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 24/88 (27%), Positives = 45/88 (51%), Gaps = 9/88 (10%)
Query 264 DIPLGATVRNEMDS------VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
D LG +V +++ + + I+ GAAE G +H+GD VL +NG+ + G +
Sbjct 1364 DGSLGISVTGGVNTSVRHGGIYVKAIIPKGAAESDGRIHKGDRVLAVNGVSLEGATHKQA 1423
Query 318 FDLLSDMHGTLTFVLIPSQQIKPPPAKE 345
+ L + G + +L+ Q+ P ++E
Sbjct 1424 VETLRNT-GQVVHLLLEKGQV--PTSRE 1448
Score = 38.1 bits (87), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 20/72 (28%), Positives = 35/72 (49%), Gaps = 1/72 (1%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
V IS + GG A+ G L GD ++ +N + + G + D+L + +T V+ ++
Sbjct 1112 VFISAVTPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAVDILQNAPEDVTLVISQPKE 1171
Query 338 IKPPPAKETVIH 349
KP T +H
Sbjct 1172 -KPSKVPSTPVH 1182
>sp|Q8MJ49|OSTF1_PIG Osteoclast-stimulating factor 1 OS=Sus scrofa
OX=9823 GN=OSTF1 PE=2 SV=1
Length=214
Score = 38.1 bits (87), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 16/55 (29%), Positives = 28/55 (51%), Gaps = 6/55 (11%)
Query 371 LSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEE 425
L F++GDI+++ D NWW+ +G GL+P +Q E++ + E
Sbjct 31 LYFEEGDIIYITDMSDTNWWKGTSKG------RTGLIPSNYVAEQAESIDNPLHE 79
>sp|A1DFN5|HSE1_NEOFI Class E vacuolar protein-sorting machinery
protein hse1 OS=Neosartorya fischeri (strain ATCC 1020 /
DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB
181) OX=331117 GN=hse1 PE=3 SV=1
Length=603
Score = 38.9 bits (89), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 48/167 (29%), Positives = 79/167 (47%), Gaps = 26/167 (16%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELG-LSFQKGDILHVISQEDPNWWQAY 393
SQ + P + TV V+A FD+ PS E G L F+KGDI+ V+ +WW+
Sbjct 205 SQAVPPGTSAATVSRVRALFDFQPS--------EPGELQFRKGDIIAVLESVYKDWWKGS 256
Query 394 REGDEDNQPLAGLVPGKSFQQQREAMKQTIEE-DKEPEKSGKLWCAKKNKKKRKKVLYN- 451
G G+ P ++ + T+EE +E + +++ KN +K +L
Sbjct 257 LRGQ------TGIFPLNYVEKLPDP---TVEELQREAQMEAEVFGQIKNVEKLLTLLSTR 307
Query 452 ANKNDDYDNEEILTYEEMSLYHQPAN-RKRPIILIGPQNCGQNELRQ 497
+++ + DNEEI +LYH + R + I LIG + ++E Q
Sbjct 308 SSELNVQDNEEI-----TALYHSTLSIRPKLIELIGKYSQKKDEFTQ 349
>sp|Q9XYM0|CRK_DROME Adapter molecule Crk OS=Drosophila melanogaster
OX=7227 GN=Crk PE=1 SV=1
Length=271
Score = 38.5 bits (88), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 29/108 (27%), Positives = 46/108 (43%), Gaps = 14/108 (13%)
Query 328 LTFVLIPSQQIKP--PPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE 385
LTF + P PA V V FD+ SD +P FQ+G++L ++ ++
Sbjct 87 LTFYTLHYLDTTPLKRPACRRVEKVIGKFDFVGSDQDDLP-------FQRGEVLTIVRKD 139
Query 386 DPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSG 433
+ WW A ++ G +P QQ + M + + EP SG
Sbjct 140 EDQWWTA-----RNSSGKIGQIPVPYIQQYDDYMDEDAIDKNEPSISG 182
>sp|Q92882|OSTF1_HUMAN Osteoclast-stimulating factor 1 OS=Homo
sapiens OX=9606 GN=OSTF1 PE=1 SV=2
Length=214
Score = 38.1 bits (87), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 16/55 (29%), Positives = 28/55 (51%), Gaps = 6/55 (11%)
Query 371 LSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEE 425
L F++GDI+++ D NWW+ +G GL+P +Q E++ + E
Sbjct 31 LYFEEGDIIYITDMSDTNWWKGTSKG------RTGLIPSNYVAEQAESIDNPLHE 79
>sp|O70248|APBA3_RAT Amyloid-beta A4 precursor protein-binding
family A member 3 OS=Rattus norvegicus OX=10116 GN=Apba3 PE=1
SV=2
Length=569
Score = 38.9 bits (89), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 22/77 (29%), Positives = 37/77 (48%), Gaps = 7/77 (9%)
Query 275 MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM--HGTLTFVL 332
+ + +I+ ++ GG AE+ G L GD V ING + G + + ++ H ++T +
Sbjct 413 LPTAVIANLLHGGPAERCGALSIGDRVTAINGTSLVGLSLAACQAAVREVRRHSSVTLSI 472
Query 333 IPSQQIKPPPAKETVIH 349
I PP VIH
Sbjct 473 -----IHCPPVTTAVIH 484
>sp|Q9CSB4|PAR3L_MOUSE Partitioning defective 3 homolog B OS=Mus
musculus OX=10090 GN=Pard3b PE=1 SV=2
Length=1203
Score = 39.3 bits (90), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 19/60 (32%), Positives = 32/60 (53%), Gaps = 0/60 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
+ + I+ GAA K G L GD +LE+NG ++ G+ E+ +L T L+ ++Q
Sbjct 410 IFVKNILPKGAAVKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETVSLVIARQ 469
Score = 34.7 bits (78), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 18/64 (28%), Positives = 32/64 (50%), Gaps = 7/64 (11%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL-------SDMHGTLT 329
+ I I+ GGAA K G L D+++ +NG + GK +E + L ++ G +
Sbjct 526 GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGETLLGKSNHEAMETLRRSMSMEGNIRGMIQ 585
Query 330 FVLI 333
V++
Sbjct 586 LVIL 589
>sp|Q9P227|RHG23_HUMAN Rho GTPase-activating protein 23 OS=Homo
sapiens OX=9606 GN=ARHGAP23 PE=1 SV=2
Length=1491
Score = 39.3 bits (90), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 17/60 (28%), Positives = 35/60 (58%), Gaps = 1/60 (2%)
Query 275 MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP 334
MD++ + + + G A ++GL GD ++++NG + GK ++V L+ + TL ++P
Sbjct 95 MDTIFVKNVKEDGPAHRAGL-RTGDRLVKVNGESVIGKTYSQVIALIQNSDDTLELSIMP 153
>sp|Q9JKS6|PCLO_RAT Protein piccolo OS=Rattus norvegicus OX=10116
GN=Pclo PE=1 SV=1
Length=5085
Score = 39.3 bits (90), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 14/75 (19%)
Query 257 VRIEKARDIP-----LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
+RI ++IP +GA I++I+ G +AE +G L EG +VLE NG+ +
Sbjct 4461 IRIVGGKEIPGHSGEIGA---------YIAKILPGESAEHTGPLMEGMQVLEWNGVPLTS 4511
Query 312 KDVNEVFDLLSDMHG 326
K EV +++ G
Sbjct 4512 KTYEEVQSIINQQSG 4526
>sp|Q9UQ26|RIMS2_HUMAN Regulating synaptic membrane exocytosis
protein 2 OS=Homo sapiens OX=9606 GN=RIMS2 PE=1 SV=2
Length=1411
Score = 38.9 bits (89), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 17/44 (39%), Positives = 27/44 (61%), Gaps = 0/44 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
I+++ KG A+ G L GDEVLE NG ++G EV++++
Sbjct 696 AFITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNII 739
>sp|Q9P202|WHRN_HUMAN Whirlin OS=Homo sapiens OX=9606 GN=WHRN
PE=1 SV=4
Length=907
Score = 38.9 bits (89), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 24/80 (30%), Positives = 42/80 (53%), Gaps = 7/80 (9%)
Query 253 TVKIVRIEKARD-----IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
T +VR++K+ I GA R + ++ I +GG+A G L G +LE+NG+
Sbjct 813 TSTLVRVKKSAATLGIAIEGGANTRQPLPRIVT--IQRGGSAHNCGQLKVGHVILEVNGL 870
Query 308 EIRGKDVNEVFDLLSDMHGT 327
+RGK+ E ++++ T
Sbjct 871 TLRGKEHREAARIIAEAFKT 890
>sp|Q5RD33|APBA2_PONAB Amyloid-beta A4 precursor protein-binding
family A member 2 OS=Pongo abelii OX=9601 GN=APBA2 PE=2 SV=1
Length=749
Score = 38.9 bits (89), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 90/419 (21%), Positives = 153/419 (37%), Gaps = 103/419 (25%)
Query 40 PGDLGTRMMPIRRSAQLERIRQQQEDMRRRREEEGKKQELDLNSSM------RLKKLAQI 93
PGD P R+ + ER + E + E+ K+Q DLN + KK+A
Sbjct 293 PGDPQRGFKPKTRTPE-ERPKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASF 351
Query 94 PPKTGIDNPMF--DTEEGIVLES-------------PHYAVKILEIEDLFSSLKHIQ--- 135
P + P D +GI+ + P +++++ ++ S +K +Q
Sbjct 352 PSFVAVPGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAA 411
Query 136 ------HTLVDSQSQEDISLLLQL----VQNKDFQNAFKIH-----------NAITVHMN 174
++ D+Q+ ++ L + V N D Q H I V M
Sbjct 412 KIKKKANSEGDAQTLTEVDLFISAQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMA 471
Query 175 KASPPFPLISNAQDL------AQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAH---- 224
+ P S +QD AQE + K + H E L+ QA +A+
Sbjct 472 RRRMPR---SASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFL 528
Query 225 ----------------DKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLG 268
D + QEM D+ ++ S E K +++EK + LG
Sbjct 529 RANGINPEDLSQKEYSDIINTQEM----YNDDLIHFS----NSENCKELQLEKHKGEILG 580
Query 269 ATVRNE-----MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD 323
V + +VI++ ++ GG A +SG L GD+++ ING + G + ++
Sbjct 581 VVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKG 640
Query 324 MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVI 382
+ L I P TV+ + Y +LG S Q G I ++
Sbjct 641 LKNQTQVKL----NIVSCPPVTTVLIKRPDLKY-----------QLGFSVQNGIICSLM 684
>sp|P54283|CACB1_RAT Voltage-dependent L-type calcium channel
subunit beta-1 OS=Rattus norvegicus OX=10116 GN=Cacnb1 PE=1
SV=1
Length=597
Score = 38.9 bits (89), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 66/325 (20%), Positives = 128/325 (39%), Gaps = 35/325 (11%)
Query 344 KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW--QAYREGDEDNQ 401
K V+ + Y+PS VP + + ++F+ D LH+ + + +WW + +EG E
Sbjct 99 KPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCE--- 155
Query 402 PLAGLVPGK-SFQQQREAMKQTIEEDK----EPEKSGKLWCAKKNKKKRKKVLYNANKND 456
G +P R +QT+ +++ + + R+ + K
Sbjct 156 --VGFIPSPVKLDSLRLLQEQTLRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPASAKQK 213
Query 457 DYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKEKDRFASAVPH 513
E + Y+ + RPIIL+GP G + +++ L + K RF +
Sbjct 214 QKSTEHVPPYDVVP-------SMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-S 265
Query 514 TTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKIC 573
TR D +A R + + + IE +L + R + +
Sbjct 266 ITRVTADISLAKR--------SVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQ 317
Query 574 LLSLRTQSLK---TLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTRE 630
L++L ++ L + L P I++I S + L+ L+ GK+ + + L I + +
Sbjct 318 LVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKS-QSKHLNVQIAASEK 376
Query 631 MEQNNGHYFDTAIVNSDLDKAYQEL 655
+ Q FD + + L+ A + L
Sbjct 377 LAQCPPEMFDIILDENQLEDACEHL 401
>sp|Q6IN97|FRP2L_HUMAN Putative protein FRMPD2-like OS=Homo sapiens
OX=9606 GN=FRMPD2B PE=5 SV=1
Length=320
Score = 38.5 bits (88), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 23/68 (34%), Positives = 32/68 (47%), Gaps = 5/68 (7%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
D V I R+ G AE++G + GD +L +NG G EV LL +T +L
Sbjct 118 DLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL--- 174
Query 336 QQIKPPPA 343
+PPP
Sbjct 175 --CRPPPG 180
>sp|Q9JIS1|RIMS2_RAT Regulating synaptic membrane exocytosis protein
2 OS=Rattus norvegicus OX=10116 GN=Rims2 PE=1 SV=1
Length=1555
Score = 38.9 bits (89), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 17/44 (39%), Positives = 27/44 (61%), Gaps = 0/44 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
I+++ KG A+ G L GDEVLE NG ++G EV++++
Sbjct 618 AFITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNII 661
>sp|Q6TGW5|OSTF1_DANRE Osteoclast-stimulating factor 1 OS=Danio
rerio OX=7955 GN=ostf1 PE=2 SV=1
Length=214
Score = 37.7 bits (86), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 22/77 (29%), Positives = 35/77 (45%), Gaps = 17/77 (22%)
Query 351 KAHFDYDPS--DDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+A F +DP D+ Y F++GDIL++ D NWW+ G GL+P
Sbjct 18 RALFTFDPRTPDELY---------FEEGDILYISDTSDSNWWKGTCRG------RTGLIP 62
Query 409 GKSFQQQREAMKQTIEE 425
+Q E++ + E
Sbjct 63 SNYVAEQAESIDNPMHE 79
>sp|Q96L92|SNX27_HUMAN Sorting nexin-27 OS=Homo sapiens OX=9606
GN=SNX27 PE=1 SV=2
Length=541
Score = 38.5 bits (88), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 27/94 (29%), Positives = 45/94 (48%), Gaps = 20/94 (21%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
+S ++ GGAA+++G+ +GD +LE+N + + G +V DL+ L ++
Sbjct 81 VSAVLPGGAADRAGV-RKGDRILEVNHVNVEGATHKQVVDLIRAGEKELILTVLSV---- 135
Query 340 PPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSF 373
PP + + DPSDD LG SF
Sbjct 136 PPHEADNL---------DPSDD------SLGQSF 154
>sp|Q8MJ50|OSTF1_BOVIN Osteoclast-stimulating factor 1 OS=Bos
taurus OX=9913 GN=OSTF1 PE=2 SV=1
Length=214
Score = 37.4 bits (85), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 16/55 (29%), Positives = 28/55 (51%), Gaps = 6/55 (11%)
Query 371 LSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEE 425
L F++GDI+++ D NWW+ +G GL+P +Q E++ + E
Sbjct 31 LYFEEGDIIYITDMSDTNWWKGTCKG------RTGLIPSNYVAEQAESIDNPLHE 79
>sp|Q9EQZ7|RIMS2_MOUSE Regulating synaptic membrane exocytosis
protein 2 OS=Mus musculus OX=10090 GN=Rims2 PE=1 SV=1
Length=1530
Score = 38.5 bits (88), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 17/44 (39%), Positives = 27/44 (61%), Gaps = 0/44 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
I+++ KG A+ G L GDEVLE NG ++G EV++++
Sbjct 705 AFITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNII 748
>sp|Q6XJU9|OSTF1_MONAL Osteoclast-stimulating factor 1 OS=Monopterus
albus OX=43700 GN=ostf1 PE=2 SV=1
Length=214
Score = 37.4 bits (85), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 22/77 (29%), Positives = 34/77 (44%), Gaps = 17/77 (22%)
Query 351 KAHFDYDPS--DDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+A F +DP D+ Y F++GDIL++ D NWW+ G GL+P
Sbjct 18 RALFTFDPRTPDELY---------FEEGDILYISDTSDTNWWKGTCRG------RTGLIP 62
Query 409 GKSFQQQREAMKQTIEE 425
+Q E + + E
Sbjct 63 SNYVAEQAETIDHPMHE 79
>sp|Q14005|IL16_HUMAN Pro-interleukin-16 OS=Homo sapiens OX=9606
GN=IL16 PE=1 SV=4
Length=1332
Score = 38.5 bits (88), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 18/56 (32%), Positives = 35/56 (63%), Gaps = 1/56 (2%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM-HGTLTFVL 332
+ I+RI KG A+E+S + GDE+L++ G ++G E ++++ + G +T V+
Sbjct 1261 LTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVI 1316
>sp|Q8R3Z5|CACB1_MOUSE Voltage-dependent L-type calcium channel
subunit beta-1 OS=Mus musculus OX=10090 GN=Cacnb1 PE=1 SV=1
Length=597
Score = 38.1 bits (87), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 66/325 (20%), Positives = 128/325 (39%), Gaps = 35/325 (11%)
Query 344 KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW--QAYREGDEDNQ 401
K V+ + Y+PS VP + + ++F+ D LH+ + + +WW + +EG E
Sbjct 99 KPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCE--- 155
Query 402 PLAGLVPGK-SFQQQREAMKQTIEEDK----EPEKSGKLWCAKKNKKKRKKVLYNANKND 456
G +P R +QT+ +++ + + R+ + K
Sbjct 156 --VGFIPSPVKLDSLRLLQEQTLRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPASAKQK 213
Query 457 DYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKEKDRFASAVPH 513
E + Y+ + RPIIL+GP G + +++ L + K RF +
Sbjct 214 QKSTEHVPPYDVVP-------SMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-S 265
Query 514 TTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKIC 573
TR D +A R + + + IE +L + R + +
Sbjct 266 ITRVTADISLAKR--------SVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQ 317
Query 574 LLSLRTQSLK---TLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTRE 630
L++L ++ L + L P I++I S + L+ L+ GK+ + + L I + +
Sbjct 318 LVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKS-QSKHLNVQIAASEK 376
Query 631 MEQNNGHYFDTAIVNSDLDKAYQEL 655
+ Q FD + + L+ A + L
Sbjct 377 LAQCPPEMFDIILDENQLEDACEHL 401
>sp|A7E8B6|SLA1_SCLS1 Actin cytoskeleton-regulatory complex protein
sla1 OS=Sclerotinia sclerotiorum (strain ATCC 18683 /
1980 / Ss-1) OX=665079 GN=sla1 PE=3 SV=2
Length=1150
Score = 38.5 bits (88), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 23/61 (38%), Positives = 35/61 (57%), Gaps = 4/61 (7%)
Query 363 YVPCRELGLSFQKGDILHVI--SQEDPNWWQAYREGD-EDNQPLAGLVPGKSFQQQREAM 419
YVP E L+ ++GDIL+V+ S ED +WW+A ++ ED GL+P Q+ +
Sbjct 13 YVPAGEGELTIKEGDILYVLEKSTED-DWWKAKKKASAEDEDEPVGLIPNNYIQEAAPSG 71
Query 420 K 420
K
Sbjct 72 K 72
>sp|Q5ZJJ9|OSTF1_CHICK Osteoclast-stimulating factor 1 OS=Gallus
gallus OX=9031 GN=OSTF1 PE=2 SV=1
Length=202
Score = 37.0 bits (84), Expect = 0.27, Method: Composition-based stats.
Identities = 16/55 (29%), Positives = 28/55 (51%), Gaps = 6/55 (11%)
Query 371 LSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEE 425
L F++GDI+++ D NWW+ +G GL+P +Q E++ + E
Sbjct 31 LYFEEGDIIYISDMSDTNWWKGTCKGR------TGLIPSNYVAEQAESIDNPLHE 79
>sp|Q925E0|SNTG2_MOUSE Gamma-2-syntrophin OS=Mus musculus OX=10090
GN=Sntg2 PE=1 SV=1
Length=539
Score = 38.1 bits (87), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 19/44 (43%), Positives = 28/44 (64%), Gaps = 0/44 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
V+IS+I K AA+++ +L GD VL++NGI + EV LL
Sbjct 98 VVISKIFKDQAADQTEMLFIGDAVLQVNGINVENATHEEVVHLL 141
>sp|O34666|CTPA_BACSU Carboxy-terminal processing protease CtpA
OS=Bacillus subtilis (strain 168) OX=224308 GN=ctpA PE=2 SV=1
Length=466
Score = 38.1 bits (87), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 20/61 (33%), Positives = 36/61 (59%), Gaps = 1/61 (2%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
+GA V + ++I +KG AEK+G+ D+++++NG ++G +VNE L+ G
Sbjct 106 IGAQVEEKDGEILIVSPIKGSPAEKAGIKPR-DQIIKVNGKSVKGMNVNEAVALIRGKKG 164
Query 327 T 327
T
Sbjct 165 T 165
>sp|Q15811|ITSN1_HUMAN Intersectin-1 OS=Homo sapiens OX=9606 GN=ITSN1
PE=1 SV=3
Length=1721
Score = 38.1 bits (87), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 21/66 (32%), Positives = 31/66 (47%), Gaps = 13/66 (20%)
Query 343 AKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQP 402
A V V +DY +D L+F KG I++V+++EDP+WW+ G
Sbjct 1153 ALAAVCQVIGMYDYTAQNDDE-------LAFNKGQIINVLNKEDPDWWKGEVNGQ----- 1200
Query 403 LAGLVP 408
GL P
Sbjct 1201 -VGLFP 1205
>sp|Q9WVJ4|SYJ2B_RAT Synaptojanin-2-binding protein OS=Rattus
norvegicus OX=10116 GN=Synj2bp PE=1 SV=2
Length=145
Score = 36.2 bits (82), Expect = 0.31, Method: Composition-based stats.
Identities = 16/46 (35%), Positives = 28/46 (61%), Gaps = 0/46 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD 323
+ +SRI + GAA + G L EGD++L +NG +++ + DL +
Sbjct 42 IYVSRIKEDGAAARDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRN 87
>sp|P34109|MYOD_DICDI Myosin ID heavy chain OS=Dictyostelium discoideum
OX=44689 GN=myoD PE=1 SV=2
Length=1109
Score = 38.1 bits (87), Expect = 0.33, Method: Compositional matrix adjust.
Identities = 20/61 (33%), Positives = 28/61 (46%), Gaps = 7/61 (11%)
Query 342 PAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQ 401
PA KA +D+D + LSF++GDIL V+ Q +WW A +G
Sbjct 955 PASNVKPSAKALYDFDAES-------SMELSFKEGDILTVLDQSSGDWWDAELKGRRGKV 1007
Query 402 P 402
P
Sbjct 1008 P 1008
>sp|O35431|APBA2_RAT Amyloid-beta A4 precursor protein-binding
family A member 2 OS=Rattus norvegicus OX=10116 GN=Apba2 PE=1
SV=1
Length=750
Score = 38.1 bits (87), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 21/65 (32%), Positives = 36/65 (55%), Gaps = 5/65 (8%)
Query 252 ETVKIVRIEKARDIPLGATVRNE-----MDSVIISRIVKGGAAEKSGLLHEGDEVLEING 306
E K +++EK + LG V + +VI++ ++ GG A +SG L GD+++ ING
Sbjct 565 ENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSING 624
Query 307 IEIRG 311
+ G
Sbjct 625 TSLVG 629
>sp|Q5RBI7|PDZD7_PONAB PDZ domain-containing protein 7 OS=Pongo
abelii OX=9601 GN=PDZD7 PE=2 SV=2
Length=1005
Score = 38.1 bits (87), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 20/69 (29%), Positives = 40/69 (58%), Gaps = 4/69 (6%)
Query 257 VRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
VR+EK+ LG +VR + + +S++ +G +AE++GL GD++ E+NG+ +
Sbjct 87 VRVEKSPAGRLGFSVRGGSEHGLGIFVSKVEEGSSAERAGLC-VGDKITEVNGLSLESTT 145
Query 314 VNEVFDLLS 322
+ +L+
Sbjct 146 MGSAVKVLT 154
>sp|P05433|GAGC_AVISC P47(GAG-CRK) protein OS=Avian sarcoma virus
CT10 OX=11878 PE=4 SV=1
Length=440
Score = 37.7 bits (86), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 22/65 (34%), Positives = 34/65 (52%), Gaps = 12/65 (18%)
Query 344 KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPL 403
+E V +V+A FD+ +DD +P F+KGDIL + + + WW A ED
Sbjct 367 QEEVEYVRALFDFKGNDDGDLP-------FKKGDILKIRDKPEEQWWNA-----EDMDGK 414
Query 404 AGLVP 408
G++P
Sbjct 415 RGMIP 419
>sp|W6RTA4|CLA1_CAEEL Protein clarinet OS=Caenorhabditis elegans
OX=6239 GN=cla-1 PE=1 SV=2
Length=8922
Score = 38.1 bits (87), Expect = 0.37, Method: Compositional matrix adjust.
Identities = 19/56 (34%), Positives = 31/56 (55%), Gaps = 0/56 (0%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
S +S++ + G + GDEV+E NGI +RGK EV +++ HG + V+
Sbjct 8602 SAYVSQLHSTANNQTLGQIKIGDEVVEWNGILLRGKTFEEVERIVNKSHGEIEMVI 8657
>sp|Q9H5P4|PDZD7_HUMAN PDZ domain-containing protein 7 OS=Homo
sapiens OX=9606 GN=PDZD7 PE=1 SV=2
Length=1033
Score = 38.1 bits (87), Expect = 0.37, Method: Compositional matrix adjust.
Identities = 20/69 (29%), Positives = 40/69 (58%), Gaps = 4/69 (6%)
Query 257 VRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
VR+EK+ LG +VR + + +S++ +G +AE++GL GD++ E+NG+ +
Sbjct 87 VRVEKSPAGRLGFSVRGGSEHGLGIFVSKVEEGSSAERAGLC-VGDKITEVNGLSLESTT 145
Query 314 VNEVFDLLS 322
+ +L+
Sbjct 146 MGSAVKVLT 154
>sp|Q9D6K5|SYJ2B_MOUSE Synaptojanin-2-binding protein OS=Mus musculus
OX=10090 GN=Synj2bp PE=1 SV=1
Length=145
Score = 35.8 bits (81), Expect = 0.37, Method: Composition-based stats.
Identities = 16/46 (35%), Positives = 28/46 (61%), Gaps = 0/46 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD 323
+ +SRI + GAA + G L EGD++L +NG +++ + DL +
Sbjct 42 IYVSRIKEDGAAAQDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRN 87
>sp|O62675|IL16_MACMU Pro-interleukin-16 OS=Macaca mulatta OX=9544
GN=IL16 PE=2 SV=1
Length=630
Score = 37.7 bits (86), Expect = 0.37, Method: Compositional matrix adjust.
Identities = 18/56 (32%), Positives = 35/56 (63%), Gaps = 1/56 (2%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM-HGTLTFVL 332
+ I+RI KG A+E+S + GDE+L++ G ++G E ++++ + G +T V+
Sbjct 559 LTINRIFKGAASEQSETIQPGDEILQLAGTAMQGLTRFEAWNIIKALPDGPVTIVI 614
>sp|O62674|IL16_CHLAE Pro-interleukin-16 OS=Chlorocebus aethiops
OX=9534 GN=IL16 PE=2 SV=1
Length=631
Score = 37.7 bits (86), Expect = 0.41, Method: Compositional matrix adjust.
Identities = 18/56 (32%), Positives = 35/56 (63%), Gaps = 1/56 (2%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM-HGTLTFVL 332
+ I+RI KG A+E+S + GDE+L++ G ++G E ++++ + G +T V+
Sbjct 560 LTINRIFKGAASEQSETIQPGDEILQLAGTAMQGLTRFEAWNIIKALPDGPVTIVI 615
>sp|Q8TEW8|PAR3L_HUMAN Partitioning defective 3 homolog B OS=Homo
sapiens OX=9606 GN=PARD3B PE=1 SV=2
Length=1205
Score = 37.7 bits (86), Expect = 0.42, Method: Compositional matrix adjust.
Identities = 19/60 (32%), Positives = 32/60 (53%), Gaps = 0/60 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
+ + I+ GAA K G L GD +LE+NG ++ G+ E+ +L T L+ ++Q
Sbjct 410 IFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVIARQ 469
Score = 34.7 bits (78), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 18/64 (28%), Positives = 32/64 (50%), Gaps = 7/64 (11%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL-------SDMHGTLT 329
+ I I+ GGAA K G L D+++ +NG + GK +E + L ++ G +
Sbjct 526 GIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQ 585
Query 330 FVLI 333
V++
Sbjct 586 LVIL 589
>sp|Q68DX3|FRPD2_HUMAN FERM and PDZ domain-containing protein
2 OS=Homo sapiens OX=9606 GN=FRMPD2 PE=1 SV=3
Length=1309
Score = 37.7 bits (86), Expect = 0.42, Method: Compositional matrix adjust.
Identities = 23/68 (34%), Positives = 32/68 (47%), Gaps = 5/68 (7%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
D V I R+ G AE++G + GD +L +NG G EV LL +T +L
Sbjct 1107 DLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLL--- 1163
Query 336 QQIKPPPA 343
+PPP
Sbjct 1164 --CRPPPG 1169
Score = 34.3 bits (77), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 23/77 (30%), Positives = 37/77 (48%), Gaps = 8/77 (10%)
Query 255 KIVRIEKARDIPLG-ATVRNEMD-------SVIISRIVKGGAAEKSGLLHEGDEVLEING 306
+IVR+ RD G V NE + + IS I+ GG AEK+ + G ++L +N
Sbjct 772 EIVRVTLKRDPHRGFGFVINEGEYSGQADPGIFISSIIPGGPAEKAKTIKPGGQILALNH 831
Query 307 IEIRGKDVNEVFDLLSD 323
I + G N ++ +
Sbjct 832 ISLEGFTFNMAVRMIQN 848
>sp|O54824|IL16_MOUSE Pro-interleukin-16 OS=Mus musculus OX=10090
GN=Il16 PE=1 SV=3
Length=1322
Score = 37.7 bits (86), Expect = 0.47, Method: Compositional matrix adjust.
Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 2/54 (4%)
Query 268 GATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
GA + N++ + + R+ G A + G + +G+EVL ING ++G N+ +L
Sbjct 1124 GADLENKV--ITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGATHNDALAIL 1175
>sp|Q0V8R5|IL16_BOVIN Pro-interleukin-16 OS=Bos taurus OX=9913
GN=IL16 PE=2 SV=1
Length=627
Score = 37.4 bits (85), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 2/54 (4%)
Query 268 GATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
GA + N++ + + R+ G A + G + +G+EVL ING ++G N+ +L
Sbjct 427 GADLENKV--ITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGATHNDALAIL 478
>sp|Q0CJU8|HSE1_ASPTN Class E vacuolar protein-sorting machinery
protein hse1 OS=Aspergillus terreus (strain NIH 2624 / FGSC
A1156) OX=341663 GN=hse1 PE=3 SV=1
Length=597
Score = 37.4 bits (85), Expect = 0.50, Method: Compositional matrix adjust.
Identities = 50/182 (27%), Positives = 79/182 (43%), Gaps = 38/182 (21%)
Query 346 TVIHVKAHFDYDPSDDPYVPCRELG-LSFQKGDILHVISQEDPNWWQAYREGDEDNQPLA 404
TV V+A FD+ PS E G L F+KGD++ V+ +WW+ G
Sbjct 225 TVSRVRALFDFQPS--------EPGELQFRKGDVIAVLESVYKDWWKGSLRGQ------T 270
Query 405 GLVPGKSFQQQREAMKQTIEE-DKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDY-DNEE 462
G+ P ++ + T+EE +E + +++ KN +K +L + + DNEE
Sbjct 271 GIFPLNYVEKLPDP---TVEELQREAQMEAEVFGQIKNVEKLLTLLSTRSSEPNVQDNEE 327
Query 463 ILTYEEMSLYHQP-ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQ 521
I +LYH A R + I LIG +++KD F ++RRD
Sbjct 328 I-----TALYHSTLAIRPKLIELIG------------KYSQKKDEFTQLNEKFIKARRDY 370
Query 522 EV 523
E
Sbjct 371 EA 372
>sp|Q04929|CRK_CHICK Adapter molecule crk OS=Gallus gallus OX=9031
GN=CRK PE=1 SV=1
Length=305
Score = 37.0 bits (84), Expect = 0.51, Method: Compositional matrix adjust.
Identities = 22/65 (34%), Positives = 35/65 (54%), Gaps = 12/65 (18%)
Query 344 KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPL 403
+E V +V+A FD++ +DD +P F+KGDIL + + + WW A ED
Sbjct 132 QEEVEYVRALFDFNGNDDEDLP-------FKKGDILKIRDKPEEQWWNA-----EDMDGK 179
Query 404 AGLVP 408
G++P
Sbjct 180 RGMIP 184
>sp|O62666|IL16_PANTR Pro-interleukin-16 OS=Pan troglodytes OX=9598
GN=IL16 PE=2 SV=1
Length=631
Score = 37.4 bits (85), Expect = 0.52, Method: Compositional matrix adjust.
Identities = 18/56 (32%), Positives = 35/56 (63%), Gaps = 1/56 (2%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM-HGTLTFVL 332
+ I+RI KG A+E+S + GDE+L++ G ++G E ++++ + G +T V+
Sbjct 560 LTINRIFKGAASEQSETVQPGDEILQLAGTAMQGLTRFEAWNIIKALPDGPVTIVI 615
Score = 37.4 bits (85), Expect = 0.55, Method: Compositional matrix adjust.
Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 2/54 (4%)
Query 268 GATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
GA + N++ + + R+ G A + G + +G+EVL ING ++G N+ +L
Sbjct 430 GADLENKV--ITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHNDALAIL 481
>sp|P0A1B9|SCTN1_SALTY SPI-1 type 3 secretion system ATPase OS=Salmonella
typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
OX=99287 GN=sctN1 PE=1 SV=1
Length=431
Score = 37.0 bits (84), Expect = 0.54, Method: Compositional matrix adjust.
Identities = 49/180 (27%), Positives = 76/180 (42%), Gaps = 24/180 (13%)
Query 165 IHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAH 224
+ A V + + LI NAQ L+++V VL P G+ L+A + + A+L
Sbjct 46 VARAQVVGLQRERTVLSLIGNAQGLSRDV--VLYPT----GRALSAWVGYSVLGAVLDPT 99
Query 225 DKVAEQEM-QLEPITDERVYE----SIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVI 279
K+ E+ ++ PI++ERV + S G ++ +A D L V M
Sbjct 100 GKIVERFTPEVAPISEERVIDVAPPSYASRVGVREPLITGVRAIDGLLTCGVGQRMG--- 156
Query 280 ISRIVKGGAAEKSGLLH------EGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
I K+ L+H E D V I I RG++V E D+L H VL+
Sbjct 157 ---IFASAGCGKTMLMHMLIEQTEAD-VFVIGLIGERGREVTEFVDMLRASHKKEKCVLV 212
>sp|P0A1C0|SCTN1_SALTI SPI-1 type 3 secretion system ATPase OS=Salmonella
typhi OX=90370 GN=sctN1 PE=3 SV=1
Length=431
Score = 37.0 bits (84), Expect = 0.54, Method: Compositional matrix adjust.
Identities = 49/180 (27%), Positives = 76/180 (42%), Gaps = 24/180 (13%)
Query 165 IHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAH 224
+ A V + + LI NAQ L+++V VL P G+ L+A + + A+L
Sbjct 46 VARAQVVGLQRERTVLSLIGNAQGLSRDV--VLYPT----GRALSAWVGYSVLGAVLDPT 99
Query 225 DKVAEQEM-QLEPITDERVYE----SIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVI 279
K+ E+ ++ PI++ERV + S G ++ +A D L V M
Sbjct 100 GKIVERFTPEVAPISEERVIDVAPPSYASRVGVREPLITGVRAIDGLLTCGVGQRMG--- 156
Query 280 ISRIVKGGAAEKSGLLH------EGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
I K+ L+H E D V I I RG++V E D+L H VL+
Sbjct 157 ---IFASAGCGKTMLMHMLIEQTEAD-VFVIGLIGERGREVTEFVDMLRASHKKEKCVLV 212
>sp|O62678|IL16_AOTTR Pro-interleukin-16 OS=Aotus trivirgatus
OX=9505 GN=IL16 PE=2 SV=1
Length=632
Score = 37.4 bits (85), Expect = 0.56, Method: Compositional matrix adjust.
Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 2/54 (4%)
Query 268 GATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
GA + N++ + + R+ G A + G + +G+EVL ING ++G N+ +L
Sbjct 431 GADLENKV--ITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHNDALAIL 482
Score = 36.6 bits (83), Expect = 0.94, Method: Compositional matrix adjust.
Identities = 18/56 (32%), Positives = 34/56 (61%), Gaps = 1/56 (2%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM-HGTLTFVL 332
+ I+RI KG A+E+S + GDE+L + G ++G E ++++ + G +T V+
Sbjct 561 LTINRIFKGAASEQSETVQPGDEILHLAGTAMQGLTRFEAWNIIKALPDGPVTIVI 616
>sp|Q1E878|HSE1_COCIM Class E vacuolar protein-sorting machinery
protein HSE1 OS=Coccidioides immitis (strain RS) OX=246410
GN=HSE1 PE=3 SV=1
Length=612
Score = 37.4 bits (85), Expect = 0.57, Method: Compositional matrix adjust.
Identities = 51/193 (26%), Positives = 83/193 (43%), Gaps = 36/193 (19%)
Query 334 PSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELG-LSFQKGDILHVISQEDPNWWQA 392
PSQ I TV V+A +D+ PS E G L F+KGDI+ V+ +WW+
Sbjct 204 PSQGIPSGTTAATVSRVRALYDFQPS--------EPGELQFRKGDIIAVLESVYKDWWKG 255
Query 393 YREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNA 452
G G+ P ++ + ++ ++ +E + +++ KN +K +L +
Sbjct 256 SLRGQ------VGIFPLNYVEKLSDPTQEELQ--REAQMEAEVFAEIKNVEKLLALLSTS 307
Query 453 NKN-DDYDNEEILTYEEMSLYHQP-ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASA 510
+ + +NEEI LYH A R + I LIG +K+KD F
Sbjct 308 SPELNVQENEEI-----TKLYHSTLAIRPKLIELIG------------KYSKKKDDFTQL 350
Query 511 VPHTTRSRRDQEV 523
++RRD E
Sbjct 351 NEKFIKARRDYEA 363
>sp|Q63768|CRK_RAT Adapter molecule crk OS=Rattus norvegicus OX=10116
GN=Crk PE=1 SV=1
Length=304
Score = 36.6 bits (83), Expect = 0.57, Method: Compositional matrix adjust.
Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 12/75 (16%)
Query 344 KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPL 403
+E +V+A FD++ +D+ +P F+KGDIL + + + WW A ED++
Sbjct 131 QEEAEYVRALFDFNGNDEEDLP-------FKKGDILRIRDKPEEQWWNA-----EDSEGK 178
Query 404 AGLVPGKSFQQQREA 418
G++P ++ R A
Sbjct 179 RGMIPVPYVEKYRPA 193
>sp|Q9QY53|NPHP1_MOUSE Nephrocystin-1 OS=Mus musculus OX=10090
GN=Nphp1 PE=1 SV=1
Length=687
Score = 37.4 bits (85), Expect = 0.58, Method: Compositional matrix adjust.
Identities = 15/38 (39%), Positives = 25/38 (66%), Gaps = 5/38 (13%)
Query 371 LSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
L+F+KGD+LH+I ++ WW A +D + + GL+P
Sbjct 174 LTFKKGDVLHIIEKKPDGWWLA-----KDAEGVEGLIP 206
>sp|Q86UR5|RIMS1_HUMAN Regulating synaptic membrane exocytosis
protein 1 OS=Homo sapiens OX=9606 GN=RIMS1 PE=1 SV=1
Length=1692
Score = 37.4 bits (85), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 17/44 (39%), Positives = 26/44 (59%), Gaps = 0/44 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
I+++ KG A+ G L GDEVLE NG + G EV++++
Sbjct 633 AFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNII 676
>sp|P46108|CRK_HUMAN Adapter molecule crk OS=Homo sapiens OX=9606
GN=CRK PE=1 SV=2
Length=304
Score = 36.6 bits (83), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 12/75 (16%)
Query 344 KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPL 403
+E +V+A FD++ +D+ +P F+KGDIL + + + WW A ED++
Sbjct 131 QEEAEYVRALFDFNGNDEEDLP-------FKKGDILRIRDKPEEQWWNA-----EDSEGK 178
Query 404 AGLVPGKSFQQQREA 418
G++P ++ R A
Sbjct 179 RGMIPVPYVEKYRPA 193
>sp|O62677|IL16_SAISC Pro-interleukin-16 OS=Saimiri sciureus OX=9521
GN=IL16 PE=2 SV=1
Length=627
Score = 37.0 bits (84), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 17/54 (31%), Positives = 31/54 (57%), Gaps = 2/54 (4%)
Query 268 GATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
GA + N++ + + R+ G A + G + +G+EVL ING ++G N+ +L
Sbjct 426 GADLENKV--ITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHNDALAIL 477
Score = 36.6 bits (83), Expect = 0.94, Method: Compositional matrix adjust.
Identities = 18/56 (32%), Positives = 34/56 (61%), Gaps = 1/56 (2%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM-HGTLTFVL 332
+ I+RI KG A+E+S + GDE+L + G ++G E ++++ + G +T V+
Sbjct 556 LTINRIFKGAASEQSETVQPGDEILHLAGTAMQGLTRFEAWNIIKALPDGPVTIVI 611
>sp|O62676|IL16_MACFA Pro-interleukin-16 OS=Macaca fascicularis
OX=9541 GN=IL16 PE=3 SV=1
Length=630
Score = 37.0 bits (84), Expect = 0.62, Method: Compositional matrix adjust.
Identities = 18/56 (32%), Positives = 35/56 (63%), Gaps = 1/56 (2%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM-HGTLTFVL 332
+ I+RI KG A+E+S + GDE+L++ G ++G E ++++ + G +T V+
Sbjct 559 LTINRIFKGAASEQSETIQPGDEILQLAGTAMQGLTRFEAWNIIKALPDGPVTTVI 614
>sp|Q3T0C9|SYJ2B_BOVIN Synaptojanin-2-binding protein OS=Bos taurus
OX=9913 GN=SYNJ2BP PE=2 SV=1
Length=145
Score = 35.4 bits (80), Expect = 0.62, Method: Composition-based stats.
Identities = 16/46 (35%), Positives = 27/46 (59%), Gaps = 0/46 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD 323
+ +SRI + GAA G L EGD++L +NG +++ + DL +
Sbjct 42 IFVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRN 87
>sp|Q64010|CRK_MOUSE Adapter molecule crk OS=Mus musculus OX=10090
GN=Crk PE=1 SV=1
Length=304
Score = 36.6 bits (83), Expect = 0.62, Method: Compositional matrix adjust.
Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 12/75 (16%)
Query 344 KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPL 403
+E +V+A FD++ +D+ +P F+KGDIL + + + WW A ED++
Sbjct 131 QEEAEYVRALFDFNGNDEEDLP-------FKKGDILRIRDKPEEQWWNA-----EDSEGK 178
Query 404 AGLVPGKSFQQQREA 418
G++P ++ R A
Sbjct 179 RGMIPVPYVEKYRPA 193
>sp|Q9MZL7|CACB1_BOVIN Voltage-dependent L-type calcium channel
subunit beta-1 OS=Bos taurus OX=9913 GN=CACNB1 PE=1 SV=1
Length=598
Score = 37.0 bits (84), Expect = 0.65, Method: Compositional matrix adjust.
Identities = 66/327 (20%), Positives = 128/327 (39%), Gaps = 39/327 (12%)
Query 344 KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW--QAYREGDEDNQ 401
K V+ + Y+PS VP + + ++F+ D LH+ + + +WW + +EG E
Sbjct 99 KPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCE--- 155
Query 402 PLAGLVPG-------KSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANK 454
G +P + Q+Q+ ++Q + + R+ + K
Sbjct 156 --VGFIPSPVKLDSLRLLQEQK--LRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPASAK 211
Query 455 NDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKEKDRFASAV 511
E + Y+ + RPIIL+GP G + +++ L + K RF +
Sbjct 212 QKQKSTEHVPPYDVVP-------SMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRI 264
Query 512 PHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGK 571
TR D +A R + + + IE +L + R +
Sbjct 265 -SITRVTADISLAKR--------SVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELART 315
Query 572 ICLLSLRTQSLK---TLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKT 628
+ L++L ++ L + L P I++I S + L+ L+ GK+ + + L I +
Sbjct 316 LQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKS-QSKHLNVQIAAS 374
Query 629 REMEQNNGHYFDTAIVNSDLDKAYQEL 655
++ Q FD + + L+ A + L
Sbjct 375 EKLAQCPPEMFDIILDENQLEDACEHL 401
>sp|Q13588|GRAP_HUMAN GRB2-related adapter protein OS=Homo sapiens
OX=9606 GN=GRAP PE=1 SV=1
Length=217
Score = 36.2 bits (82), Expect = 0.68, Method: Compositional matrix adjust.
Identities = 19/55 (35%), Positives = 30/55 (55%), Gaps = 11/55 (20%)
Query 338 IKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 392
+K P A +A FD+ D P + LSF++GDI+ V+ + DP+WW+
Sbjct 155 LKSPGA----CFAQAQFDFSAQD----PSQ---LSFRRGDIIEVLERPDPHWWRG 198
>sp|Q9F0W4|NOSZ_PSEFL Nitrous-oxide reductase OS=Pseudomonas fluorescens
OX=294 GN=nosZ PE=3 SV=1
Length=639
Score = 37.0 bits (84), Expect = 0.68, Method: Compositional matrix adjust.
Identities = 25/87 (29%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query 229 EQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGA 288
+ EM + I D + S Y G+ + LG +RNE D V++ I++ A
Sbjct 227 KMEMAFQVIVDGNLDNSDADYTGKYAASTCYNSEKAYDLGGMMRNERDWVVVFNILRIEA 286
Query 289 AEKSG--LLHEGDEVLEINGIEIRGKD 313
A K+G + +G +V ++G + GKD
Sbjct 287 AIKAGKFITLDGSKVPVVDGRKTDGKD 313
>sp|Q9JJ40|NHRF3_RAT Na(+)/H(+) exchange regulatory cofactor NHE-RF3
OS=Rattus norvegicus OX=10116 GN=Pdzk1 PE=1 SV=2
Length=523
Score = 37.0 bits (84), Expect = 0.69, Method: Compositional matrix adjust.
Identities = 20/63 (32%), Positives = 38/63 (60%), Gaps = 1/63 (2%)
Query 271 VRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTF 330
+ + D ++ I +G AEK+GLL +GD VL ING+ + ++ +V DL+ ++T
Sbjct 26 IEKDTDGHLVRVIEEGSPAEKAGLL-DGDRVLRINGVFVDKEEHAQVVDLVRKSGNSVTL 84
Query 331 VLI 333
+++
Sbjct 85 LVL 87
>sp|P19517|CACB1_RABIT Voltage-dependent L-type calcium channel
subunit beta-1 OS=Oryctolagus cuniculus OX=9986 GN=CACNB1
PE=1 SV=1
Length=524
Score = 37.0 bits (84), Expect = 0.72, Method: Compositional matrix adjust.
Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 7/68 (10%)
Query 343 AKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW--QAYREGDEDN 400
K V+ + Y+PS VP + ++F+ D LH+ + + +WW + +EG E
Sbjct 98 TKPVAFAVRTNVGYNPSPGDEVPVEGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCE-- 155
Query 401 QPLAGLVP 408
G +P
Sbjct 156 ---VGFIP 160
>sp|A5IMD9|DER_THEP1 GTPase Der OS=Thermotoga petrophila (strain
ATCC BAA-488 / DSM 13995 / JCM 10881 / RKU-1) OX=390874 GN=der
PE=3 SV=1
Length=439
Score = 36.6 bits (83), Expect = 0.73, Method: Compositional matrix adjust.
Identities = 20/52 (38%), Positives = 30/52 (58%), Gaps = 3/52 (6%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVA--GRDYHFV 531
+ ++G N G++ L ++NKE+ S +P TTR D+EV GR Y FV
Sbjct 183 VAIVGRPNVGKSTLFNAILNKER-ALVSPIPGTTRDPVDEEVFIDGRKYVFV 233
>sp|Q9JIR4|RIMS1_RAT Regulating synaptic membrane exocytosis protein
1 OS=Rattus norvegicus OX=10116 GN=Rims1 PE=1 SV=1
Length=1615
Score = 37.0 bits (84), Expect = 0.74, Method: Compositional matrix adjust.
Identities = 17/44 (39%), Positives = 26/44 (59%), Gaps = 0/44 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
I+++ KG A+ G L GDEVLE NG + G EV++++
Sbjct 647 AFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNII 690
>sp|A2QW93|HSE1_ASPNC Class E vacuolar protein-sorting machinery
protein hse1 OS=Aspergillus niger (strain ATCC MYA-4892 /
CBS 513.88 / FGSC A1513) OX=425011 GN=hse1 PE=3 SV=1
Length=611
Score = 37.0 bits (84), Expect = 0.74, Method: Compositional matrix adjust.
Identities = 45/156 (29%), Positives = 73/156 (47%), Gaps = 26/156 (17%)
Query 346 TVIHVKAHFDYDPSDDPYVPCRELG-LSFQKGDILHVISQEDPNWWQAYREGDEDNQPLA 404
TV V+A FD+ PS E G L F+KGD++ V+ +WW+ G
Sbjct 217 TVSRVRALFDFQPS--------EPGELQFRKGDVIAVLESVYKDWWKGSLRGQ------T 262
Query 405 GLVPGKSFQQQREAMKQTIEE-DKEPEKSGKLWCAKKNKKKRKKVLYN-ANKNDDYDNEE 462
G+ P ++ + T+EE +E + ++ KN +K +L +++ + DNEE
Sbjct 263 GIFPLNYVEKLPDP---TVEELQREAQMEADVFGQIKNVEKLLTLLSTRSSELNVQDNEE 319
Query 463 ILTYEEMSLYHQP-ANRKRPIILIGPQNCGQNELRQ 497
I +LYH A R + I LIG + ++E Q
Sbjct 320 I-----TALYHSTLAIRPKLIELIGKYSQKKDEFTQ 350
>sp|Q2KJA1|SH3G1_BOVIN Endophilin-A2 OS=Bos taurus OX=9913 GN=SH3GL1
PE=2 SV=1
Length=368
Score = 36.6 bits (83), Expect = 0.78, Method: Compositional matrix adjust.
Identities = 19/55 (35%), Positives = 31/55 (56%), Gaps = 7/55 (13%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLA 404
KA +D++P +D ELG F +GDI+ + +Q D NW++ +G PL+
Sbjct 311 CKALYDFEPEND-----GELG--FHEGDIITLTNQIDENWYEGMLDGQSGFFPLS 358
>sp|Q02641|CACB1_HUMAN Voltage-dependent L-type calcium channel
subunit beta-1 OS=Homo sapiens OX=9606 GN=CACNB1 PE=1 SV=3
Length=598
Score = 36.6 bits (83), Expect = 0.78, Method: Compositional matrix adjust.
Identities = 66/327 (20%), Positives = 129/327 (39%), Gaps = 39/327 (12%)
Query 344 KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW--QAYREGDEDNQ 401
K V+ + Y+PS VP + + ++F+ D LH+ + + +WW + +EG E
Sbjct 99 KPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCE--- 155
Query 402 PLAGLVPG-------KSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANK 454
G +P + Q+Q+ ++Q + + R+ + K
Sbjct 156 --VGFIPSPVKLDSLRLLQEQK--LRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAK 211
Query 455 NDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKEKDRFASAV 511
E + Y+ + RPIIL+GP G + +++ L + K RF +
Sbjct 212 QKQKSTEHVPPYDVVP-------SMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRI 264
Query 512 PHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNL--YGTSIDSVRQVINS 569
TR D +A R + + + IE +L + I+ + ++ +
Sbjct 265 -SITRVTADISLAKR--------SVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELART 315
Query 570 GKICLLSLRT-QSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKT 628
++ L T L + L P I++I S + L+ L+ GK+ + + L I +
Sbjct 316 LQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKS-QSKHLNVQIAAS 374
Query 629 REMEQNNGHYFDTAIVNSDLDKAYQEL 655
++ Q FD + + L+ A + L
Sbjct 375 EKLAQCPPEMFDIILDENQLEDACEHL 401
>sp|Q6GGY8|CTPAL_STAAR Probable CtpA-like serine protease OS=Staphylococcus
aureus (strain MRSA252) OX=282458 GN=SAR1432 PE=3
SV=1
Length=496
Score = 36.6 bits (83), Expect = 0.83, Method: Compositional matrix adjust.
Identities = 24/89 (27%), Positives = 49/89 (55%), Gaps = 2/89 (2%)
Query 265 IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVF-DLLSD 323
+ +GA ++ + D ++++ +KG AE++G + D + ++NG I+GK ++EV D+
Sbjct 136 VGIGAEMQKKNDQIMVTSPMKGSPAERAG-IRPKDVITKVNGKSIKGKALDEVVKDVRGK 194
Query 324 MHGTLTFVLIPSQQIKPPPAKETVIHVKA 352
+ +T + + K K IHVK+
Sbjct 195 ENTEVTLTVQRGSEEKDVKIKREKIHVKS 223
>sp|P57105|SYJ2B_HUMAN Synaptojanin-2-binding protein OS=Homo
sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2
Length=145
Score = 35.0 bits (79), Expect = 0.83, Method: Composition-based stats.
Identities = 16/46 (35%), Positives = 27/46 (59%), Gaps = 0/46 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD 323
+ +SRI + GAA G L EGD++L +NG +++ + DL +
Sbjct 42 IYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRN 87
>sp|Q7A5M9|CTPAL_STAAN Probable CtpA-like serine protease OS=Staphylococcus
aureus (strain N315) OX=158879 GN=SA1253 PE=1
SV=1
Length=496
Score = 36.6 bits (83), Expect = 0.84, Method: Compositional matrix adjust.
Identities = 26/93 (28%), Positives = 51/93 (55%), Gaps = 3/93 (3%)
Query 265 IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVF-DLLSD 323
+ +GA ++ + D ++++ +KG AE++G + D + ++NG I+GK ++EV D+
Sbjct 136 VGIGAEMQKKNDQIMVTSPMKGSPAERAG-IRPKDVITKVNGKSIKGKALDEVVKDVRGK 194
Query 324 MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDY 356
+ +T + + K K IHVK+ DY
Sbjct 195 ENTEVTLTVQRGSEEKDVKIKREKIHVKS-VDY 226
>sp|Q99U67|CTPAL_STAAM Probable CtpA-like serine protease OS=Staphylococcus
aureus (strain Mu50 / ATCC 700699) OX=158878 GN=SAV1420
PE=3 SV=1
Length=496
Score = 36.6 bits (83), Expect = 0.84, Method: Compositional matrix adjust.
Identities = 26/93 (28%), Positives = 51/93 (55%), Gaps = 3/93 (3%)
Query 265 IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVF-DLLSD 323
+ +GA ++ + D ++++ +KG AE++G + D + ++NG I+GK ++EV D+
Sbjct 136 VGIGAEMQKKNDQIMVTSPMKGSPAERAG-IRPKDVITKVNGKSIKGKALDEVVKDVRGK 194
Query 324 MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDY 356
+ +T + + K K IHVK+ DY
Sbjct 195 ENTEVTLTVQRGSEEKDVKIKREKIHVKS-VDY 226
>sp|Q99NE5|RIMS1_MOUSE Regulating synaptic membrane exocytosis
protein 1 OS=Mus musculus OX=10090 GN=Rims1 PE=1 SV=2
Length=1463
Score = 37.0 bits (84), Expect = 0.85, Method: Compositional matrix adjust.
Identities = 17/44 (39%), Positives = 26/44 (59%), Gaps = 0/44 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
I+++ KG A+ G L GDEVLE NG + G EV++++
Sbjct 468 AFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNII 511
>sp|Q7KRY7|SCRIB_DROME Protein lap4 OS=Drosophila melanogaster
OX=7227 GN=scrib PE=1 SV=1
Length=1851
Score = 36.6 bits (83), Expect = 0.90, Method: Compositional matrix adjust.
Identities = 15/35 (43%), Positives = 23/35 (66%), Gaps = 0/35 (0%)
Query 272 RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEING 306
+++ D + ISRI +GG A + G + GD V+ ING
Sbjct 955 KDDCDGIFISRITEGGLAYRDGKIMVGDRVMAING 989
Score = 36.6 bits (83), Expect = 0.93, Method: Compositional matrix adjust.
Identities = 39/157 (25%), Positives = 66/157 (42%), Gaps = 26/157 (17%)
Query 167 NAITVHMNKASPPFPLISNA-QDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHD 225
+A+TV++NK P P+ A +L + +T+ K T + T
Sbjct 1183 SAVTVNVNKPQPDLPMFPAAPTELGRVTETITK-------STFTETVMT----------- 1224
Query 226 KVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVK 285
++ + ++ EP+ E V Q G I+ +P G + IS IV
Sbjct 1225 RITDNQLA-EPLISEEVVLPKNQ-GSLGFSIIGGTDHSCVPFG----TREPGIFISHIVP 1278
Query 286 GGAAEKSGLLHEGDEVLEINGIEI-RGKDVNEVFDLL 321
GG A K G L GD +L++N ++ + + V +LL
Sbjct 1279 GGIASKCGKLRMGDRILKVNEADVSKATHQDAVLELL 1315
Score = 35.4 bits (80), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 18/57 (32%), Positives = 31/57 (54%), Gaps = 1/57 (2%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
D + ISR+ + G A+ +G L GD+V+++NGI + D + +L L V+
Sbjct 759 DGIFISRVTEAGPADLAG-LKVGDKVIKVNGIVVVDADHYQAVQVLKACGAVLVLVV 814
>sp|Q80VW5|WHRN_MOUSE Whirlin OS=Mus musculus OX=10090 GN=Whrn
PE=1 SV=3
Length=918
Score = 36.6 bits (83), Expect = 0.96, Method: Compositional matrix adjust.
Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 7/80 (9%)
Query 253 TVKIVRIEKARD-----IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
T +VR+ K+ I GA R + ++ I +GG+A G L G +LE+NG
Sbjct 824 TSTLVRVRKSAATLGIAIEGGANTRQPLPRIVT--IQRGGSAHNCGQLKVGHVILEVNGQ 881
Query 308 EIRGKDVNEVFDLLSDMHGT 327
+RGK+ E ++++ T
Sbjct 882 TLRGKEHKEAARIIAEAFKT 901
>sp|A1CEK6|HSE1_ASPCL Class E vacuolar protein-sorting machinery
protein hse1 OS=Aspergillus clavatus (strain ATCC 1007 /
CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612
GN=hse1 PE=3 SV=1
Length=599
Score = 36.6 bits (83), Expect = 0.97, Method: Compositional matrix adjust.
Identities = 46/156 (29%), Positives = 73/156 (47%), Gaps = 26/156 (17%)
Query 346 TVIHVKAHFDYDPSDDPYVPCRELG-LSFQKGDILHVISQEDPNWWQAYREGDEDNQPLA 404
TV V+A FD+ PS E G L F+KGDI+ V+ +WW+ G
Sbjct 216 TVSRVRALFDFQPS--------EPGELQFRKGDIIAVLESVYKDWWKGSLRGQ------T 261
Query 405 GLVPGKSFQQQREAMKQTIEE-DKEPEKSGKLWCAKKNKKKRKKVLYN-ANKNDDYDNEE 462
G+ P ++ + T+EE +E + ++ KN +K +L +++ + DNEE
Sbjct 262 GIFPLNYVEKLPDP---TVEELQREAQMEADVFGQIKNVEKLLTLLSTRSSELNVQDNEE 318
Query 463 ILTYEEMSLYHQP-ANRKRPIILIGPQNCGQNELRQ 497
I +LYH A R + I LIG + ++E Q
Sbjct 319 I-----TALYHSTLAIRPKLIELIGKYSQKKDEFTQ 349
>sp|Q3T0X8|NHRF3_BOVIN Na(+)/H(+) exchange regulatory cofactor
NHE-RF3 OS=Bos taurus OX=9913 GN=PDZK1 PE=2 SV=1
Length=520
Score = 36.2 bits (82), Expect = 0.99, Method: Compositional matrix adjust.
Identities = 20/63 (32%), Positives = 37/63 (59%), Gaps = 1/63 (2%)
Query 271 VRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTF 330
+ + D ++ I KG AEK+GL +GD VL ING+ + ++ +V DL+ ++T
Sbjct 26 IEKDTDGHLVRVIEKGSPAEKAGL-QDGDRVLRINGVFVDKEEHMQVVDLVRKSGNSVTL 84
Query 331 VLI 333
+++
Sbjct 85 LVL 87
>sp|A7UA95|RADIL_DANRE Ras-associating and dilute domain-containing
protein OS=Danio rerio OX=7955 GN=radil PE=2 SV=1
Length=1124
Score = 36.6 bits (83), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 18/58 (31%), Positives = 27/58 (47%), Gaps = 0/58 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ I ++ G A G L GD +L +NG + G D DL+ G L F++ S
Sbjct 1054 IYIRTLIPDGPAAADGRLCIGDRILAVNGTSLIGADYQSAVDLIRLGGGRLRFLVAKS 1111
>sp|Q16A32|RBKTP_ROSDO Bifunctional ribose 1,5-bisphosphokinase-thymidine
phosphorylase OS=Roseobacter denitrificans (strain
ATCC 33942 / OCh 114) OX=375451 GN=phnN PE=3 SV=1
Length=677
Score = 36.2 bits (82), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 11/130 (8%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR---RDQEVAGRDYHFVSRQAFEA 538
+++GP G++ L + +DR A++ + R R + G DY V+ FE
Sbjct 6 FLIVGPSGVGKDTL----LEGARDRLATSRWFSFPQRVVTRAADAGGEDYIPVTPSEFEQ 61
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI- 597
+AAG F YG + R + N + L + R + + R+ I I
Sbjct 62 QLAAGAFWHQWHAHGLSYGIPMQVARDLDNGINVVLNASRNE-IGAFRDKATHVVTIGIS 120
Query 598 APPS--QERL 605
APP +ERL
Sbjct 121 APPGIVEERL 130
>sp|Q61235|SNTB2_MOUSE Beta-2-syntrophin OS=Mus musculus OX=10090
GN=Sntb2 PE=1 SV=2
Length=520
Score = 36.2 bits (82), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 3/60 (5%)
Query 254 VKIVRIEKARDIPLGATVRNEMDS---VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
V+ VR+ K LG +++ ++ ++IS+I G AA++S L GD +L +NG ++R
Sbjct 93 VRRVRVVKQEAGGLGISIKGGRENRMPILISKIFPGLAADQSRALRLGDAILSVNGTDLR 152
>sp|Q2GT05|HSE1_CHAGB Class E vacuolar protein-sorting machinery
protein HSE1 OS=Chaetomium globosum (strain ATCC 6205 / CBS
148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) OX=306901 GN=HSE1
PE=3 SV=1
Length=713
Score = 36.2 bits (82), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 51/199 (26%), Positives = 83/199 (42%), Gaps = 36/199 (18%)
Query 334 PSQQIKPPPA---KETVIHVKAHFDYDPSDDPYVPCRELG-LSFQKGDILHVISQEDPNW 389
P+ I+P P+ TV V+A +D+ PS E G L F+KGD++ V+ +W
Sbjct 211 PAAPIQPMPSGTTAATVSRVRALYDFAPS--------EPGELEFKKGDVIAVLESVYKDW 262
Query 390 WQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVL 449
W+ +G G+ P ++ + ++ +E + +++ KN +K +L
Sbjct 263 WRGSLKGK------TGIFPLNYVEKLTDPTPDELQ--REAQMEAEVFAEIKNVEKLLTLL 314
Query 450 YNANKND-DYDNEEILT-------YE---EMSLYHQPANRK-----RPIILIGPQNCGQN 493
+N + DNEEI YE E S+ H P RP I G GQN
Sbjct 315 SASNTAPREEDNEEISKFIKARRDYEALLESSMSHPPGPTYHQYAMRPQIPQGYPPPGQN 374
Query 494 ELRQRLMNKEKDRFASAVP 512
++ RF + P
Sbjct 375 YGAPPPQQQDAQRFYTPAP 393
>sp|Q99961|SH3G1_HUMAN Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1
PE=1 SV=1
Length=368
Score = 35.8 bits (81), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 18/55 (33%), Positives = 31/55 (56%), Gaps = 7/55 (13%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLA 404
KA +D++P +D ELG F +GD++ + +Q D NW++ +G PL+
Sbjct 311 CKALYDFEPEND-----GELG--FHEGDVITLTNQIDENWYEGMLDGQSGFFPLS 358
>sp|Q69Z89|RADIL_MOUSE Ras-associating and dilute domain-containing
protein OS=Mus musculus OX=10090 GN=Radil PE=1 SV=2
Length=1099
Score = 36.2 bits (82), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 19/56 (34%), Positives = 27/56 (48%), Gaps = 6/56 (11%)
Query 266 PLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
PLGA + I ++ G A G L GD++LE+NG +RG DL+
Sbjct 1021 PLGA------QGLYIQTLLPGSPAASDGRLSLGDQILEVNGSSLRGVSYMRAVDLI 1070
>sp|O42287|ITSN1_XENLA Intersectin-1 OS=Xenopus laevis OX=8355
GN=itsn1 PE=1 SV=2
Length=1705
Score = 36.2 bits (82), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 19/68 (28%), Positives = 32/68 (47%), Gaps = 18/68 (26%)
Query 371 LSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPE 430
L+F KG +++V+++EDP+WW+ G GL P + + D +P
Sbjct 1158 LAFSKGQVINVLNKEDPDWWKGELNGH------VGLFPSNYVK---------LTTDMDPS 1202
Query 431 KSGKLWCA 438
+ WCA
Sbjct 1203 QQ---WCA 1207
>sp|Q2YXZ9|CTPAL_STAAB Probable CtpA-like serine protease OS=Staphylococcus
aureus (strain bovine RF122 / ET3-1) OX=273036
GN=SAB1275c PE=3 SV=1
Length=496
Score = 36.2 bits (82), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 24/89 (27%), Positives = 49/89 (55%), Gaps = 2/89 (2%)
Query 265 IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVF-DLLSD 323
+ +GA ++ + D ++++ +KG AE++G + D + ++NG I+GK ++EV D+
Sbjct 136 VGIGAEMQKKNDQIMVTSPMKGSPAERAG-IRPKDVITKVNGKSIKGKALDEVVKDVRGK 194
Query 324 MHGTLTFVLIPSQQIKPPPAKETVIHVKA 352
+ +T + + K K IHVK+
Sbjct 195 ENTEVTLTVQRGSEEKDVKIKREKIHVKS 223
>sp|O96018|APBA3_HUMAN Amyloid-beta A4 precursor protein-binding
family A member 3 OS=Homo sapiens OX=9606 GN=APBA3 PE=1 SV=1
Length=575
Score = 36.2 bits (82), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 25/98 (26%), Positives = 42/98 (43%), Gaps = 8/98 (8%)
Query 257 VRIEKARDIPLGATVRNE-----MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
V +EK R LG + + + +I+ ++ GG AE+SG L GD + ING + G
Sbjct 395 VHLEKRRGEGLGVALVESGWGSLLPTAVIANLLHGGPAERSGALSIGDRLTAINGTSLVG 454
Query 312 KDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIH 349
+ + + + L + PP +IH
Sbjct 455 LPLAACQAAVRETKSQTSVTL---SIVHCPPVTTAIIH 489
>sp|Q5HG01|CTPAL_STAAC Probable CtpA-like serine protease OS=Staphylococcus
aureus (strain COL) OX=93062 GN=SACOL1455 PE=3
SV=1
Length=496
Score = 36.2 bits (82), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 24/89 (27%), Positives = 49/89 (55%), Gaps = 2/89 (2%)
Query 265 IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVF-DLLSD 323
+ +GA ++ + D ++++ +KG AE++G + D + ++NG I+GK ++EV D+
Sbjct 136 VGIGAEMQKKNDQIMVTSPMKGSPAERAG-IRPKDVITKVNGKSIKGKALDEVVKDVRGK 194
Query 324 MHGTLTFVLIPSQQIKPPPAKETVIHVKA 352
+ +T + + K K IHVK+
Sbjct 195 ENTEVTLTVQRGSEEKDVKIKREKIHVKS 223
>sp|Q8NWR2|CTPAL_STAAW Probable CtpA-like serine protease OS=Staphylococcus
aureus (strain MW2) OX=196620 GN=MW1310 PE=3 SV=1
Length=496
Score = 36.2 bits (82), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 24/89 (27%), Positives = 49/89 (55%), Gaps = 2/89 (2%)
Query 265 IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVF-DLLSD 323
+ +GA ++ + D ++++ +KG AE++G + D + ++NG I+GK ++EV D+
Sbjct 136 VGIGAEMQKKNDQIMVTSPMKGSPAERAG-IRPKDVITKVNGKSIKGKALDEVVKDVRGK 194
Query 324 MHGTLTFVLIPSQQIKPPPAKETVIHVKA 352
+ +T + + K K IHVK+
Sbjct 195 ENTEVTLTVQRGSEEKDVKIKREKIHVKS 223
>sp|Q6G9E1|CTPAL_STAAS Probable CtpA-like serine protease OS=Staphylococcus
aureus (strain MSSA476) OX=282459 GN=SAS1363 PE=3
SV=1
Length=496
Score = 36.2 bits (82), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 24/89 (27%), Positives = 49/89 (55%), Gaps = 2/89 (2%)
Query 265 IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVF-DLLSD 323
+ +GA ++ + D ++++ +KG AE++G + D + ++NG I+GK ++EV D+
Sbjct 136 VGIGAEMQKKNDQIMVTSPMKGSPAERAG-IRPKDVITKVNGKSIKGKALDEVVKDVRGK 194
Query 324 MHGTLTFVLIPSQQIKPPPAKETVIHVKA 352
+ +T + + K K IHVK+
Sbjct 195 ENTEVTLTVQRGSEEKDVKIKREKIHVKS 223
>sp|Q6CVA8|HSE1_KLULA Class E vacuolar protein-sorting machinery
protein HSE1 OS=Kluyveromyces lactis (strain ATCC 8585 /
CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) OX=284590
GN=HSE1 PE=3 SV=1
Length=508
Score = 36.2 bits (82), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 16/119 (13%)
Query 346 TVIH-VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLA 404
TVI V+A +D++ ++ + LSF+KGD++ V+ Q +WW+ G PL
Sbjct 222 TVIRKVRAMYDFNSTE-------QDELSFKKGDLICVVEQVYRDWWRGTLAGSVGIFPLN 274
Query 405 GLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEI 463
+ P QQ A ++ +E +++ K N + + L A D ++EI
Sbjct 275 YVTPVTEPSQQELAAERAKDE--------QVFAQKDNVDRLQNKLREAGNADITQDQEI 325
>sp|Q13425|SNTB2_HUMAN Beta-2-syntrophin OS=Homo sapiens OX=9606
GN=SNTB2 PE=1 SV=1
Length=540
Score = 36.2 bits (82), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 3/60 (5%)
Query 254 VKIVRIEKARDIPLGATVRNEMDS---VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
V+ VR+ K LG +++ ++ ++IS+I G AA++S L GD +L +NG ++R
Sbjct 113 VRRVRVVKQEAGGLGISIKGGRENRMPILISKIFPGLAADQSRALRLGDAILSVNGTDLR 172
>sp|Q9X1F8|DER_THEMA GTPase Der OS=Thermotoga maritima (strain
ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) OX=243274
GN=der PE=1 SV=1
Length=439
Score = 35.8 bits (81), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 20/52 (38%), Positives = 29/52 (56%), Gaps = 3/52 (6%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVA--GRDYHFV 531
+ ++G N G++ L ++NKE+ S +P TTR D EV GR Y FV
Sbjct 183 VAIVGRPNVGKSTLFNAILNKER-ALVSPIPGTTRDPVDDEVFIDGRKYVFV 233
>sp|Q6CHN0|SLA1_YARLI Actin cytoskeleton-regulatory complex protein
SLA1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150)
OX=284591 GN=SLA1 PE=3 SV=1
Length=1136
Score = 36.2 bits (82), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 29/83 (35%), Positives = 35/83 (42%), Gaps = 15/83 (18%)
Query 326 GTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE 385
GT L+P I+P PAK A +DYD E L+F++GD L V
Sbjct 52 GTNEIGLVPLTYIEPAPAKR---QAYALYDYDKQ-------TEEELTFKEGDALTVYDDS 101
Query 386 DPNWWQAYREGDEDNQPLAGLVP 408
D W R GDE G VP
Sbjct 102 DSEWLLVCRGGDE-----YGFVP 119
>sp|Q62422|OSTF1_MOUSE Osteoclast-stimulating factor 1 OS=Mus
musculus OX=10090 GN=Ostf1 PE=1 SV=2
Length=215
Score = 35.0 bits (79), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 15/55 (27%), Positives = 28/55 (51%), Gaps = 6/55 (11%)
Query 371 LSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEE 425
L F++GDI+++ D +WW+ +G GL+P +Q E++ + E
Sbjct 31 LYFEEGDIIYITDMSDTSWWKGTCKG------RTGLIPSNYVAEQAESIDNPLHE 79
>sp|Q6P686|OSTF1_RAT Osteoclast-stimulating factor 1 OS=Rattus
norvegicus OX=10116 GN=Ostf1 PE=1 SV=1
Length=214
Score = 35.0 bits (79), Expect = 1.4, Method: Composition-based stats.
Identities = 15/55 (27%), Positives = 28/55 (51%), Gaps = 6/55 (11%)
Query 371 LSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEE 425
L F++GDI+++ D +WW+ +G GL+P +Q E++ + E
Sbjct 31 LYFEEGDIIYITDMSDTSWWKGTCKGR------TGLIPSNYVAEQAESIDNPLHE 79
>sp|P42690|SRK4_SPOLA Tyrosine-protein kinase isoform SRK4 OS=Spongilla
lacustris OX=6055 GN=SRK1 PE=2 SV=1
Length=506
Score = 35.8 bits (81), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 17/45 (38%), Positives = 27/45 (60%), Gaps = 8/45 (18%)
Query 348 IHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 392
I+V +DYD D LSF+KGD++++IS ++ +WW A
Sbjct 58 IYV-GKYDYDSRTDD-------DLSFKKGDLMYIISTDEGDWWFA 94
>sp|E7FDW2|PZR3B_DANRE E3 ubiquitin-protein ligase PDZRN3-B OS=Danio
rerio OX=7955 GN=pdzrn3b PE=1 SV=1
Length=1053
Score = 36.2 bits (82), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 24/71 (34%), Positives = 36/71 (51%), Gaps = 6/71 (8%)
Query 267 LGATVRNEMD-----SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
LG TV D + +S I A K G + EGD +++INGIEI+ ++ V L
Sbjct 432 LGFTVCYRTDDEDETGIYVSEIDPNSIAAKDGRIREGDRIIQINGIEIQNRE-EAVALLT 490
Query 322 SDMHGTLTFVL 332
S+ H + +L
Sbjct 491 SEEHPNVCLLL 501
Score = 33.5 bits (75), Expect = 8.6, Method: Compositional matrix adjust.
Identities = 22/71 (31%), Positives = 36/71 (51%), Gaps = 11/71 (15%)
Query 250 GGETVKIVRIEKARDIPLGATV---RNEMDS--------VIISRIVKGGAAEKSGLLHEG 298
GGET + I LG + R +D+ + +S+IV+ GAA+K G L
Sbjct 241 GGETKSVTAILHRESGSLGFNIVGGRPCVDNKDGTSNEGIFVSKIVEKGAADKEGGLQIH 300
Query 299 DEVLEINGIEI 309
D ++E+NG ++
Sbjct 301 DRIMEVNGKDL 311
>sp|Q75DS3|HSE1_EREGS Class E vacuolar protein-sorting machinery
protein HSE1 OS=Eremothecium gossypii (strain ATCC 10895
/ CBS 109.51 / FGSC 9923 / NRRL Y-1056) OX=284811 GN=HSE1 PE=3
SV=1
Length=443
Score = 35.8 bits (81), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 20/55 (36%), Positives = 28/55 (51%), Gaps = 7/55 (13%)
Query 342 PAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREG 396
P + V VKA FD + S+ LSF+KGD++ VI Q +WW+ G
Sbjct 207 PQPQIVRRVKAIFDLNASEPD-------ELSFKKGDVITVIEQVYKDWWRGLLRG 254
>sp|P55196|AFAD_HUMAN Afadin OS=Homo sapiens OX=9606 GN=AFDN PE=1
SV=3
Length=1824
Score = 36.2 bits (82), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 15/53 (28%), Positives = 28/53 (53%), Gaps = 0/53 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTF 330
+ + +VKGGAA+ G L GD++L ++G + G +L++ +T
Sbjct 1035 IYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTL 1087
>sp|Q13884|SNTB1_HUMAN Beta-1-syntrophin OS=Homo sapiens OX=9606
GN=SNTB1 PE=1 SV=3
Length=538
Score = 35.8 bits (81), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 16/44 (36%), Positives = 28/44 (64%), Gaps = 0/44 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
++IS+I KG AA+++ L+ GD +L +NG ++R +E L
Sbjct 137 ILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQAL 180
>sp|P70297|STAM1_MOUSE Signal transducing adapter molecule 1 OS=Mus
musculus OX=10090 GN=Stam PE=1 SV=3
Length=548
Score = 35.8 bits (81), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 14/43 (33%), Positives = 26/43 (60%), Gaps = 7/43 (16%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 392
V+A +D++ ++D L+F+ G+I+ V+ DPNWW+
Sbjct 215 VRAVYDFEAAEDN-------ELTFKAGEIITVLDDSDPNWWKG 250
>sp|O55043|ARHG7_RAT Rho guanine nucleotide exchange factor 7
OS=Rattus norvegicus OX=10116 GN=Arhgef7 PE=1 SV=1
Length=646
Score = 35.8 bits (81), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 7/47 (15%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREG 396
V+A F++ ++ E LSF KGD++HV E+ WW+ G
Sbjct 11 VRAKFNFQQTN-------EDELSFSKGDVIHVTRVEEGGWWEGTHNG 50
>sp|Q9QZQ1|AFAD_MOUSE Afadin OS=Mus musculus OX=10090 GN=Afdn
PE=1 SV=3
Length=1820
Score = 35.8 bits (81), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 15/53 (28%), Positives = 28/53 (53%), Gaps = 0/53 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTF 330
+ + +VKGGAA+ G L GD++L ++G + G +L++ +T
Sbjct 1035 IYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTL 1087
>sp|Q9JIL4|NHRF3_MOUSE Na(+)/H(+) exchange regulatory cofactor
NHE-RF3 OS=Mus musculus OX=10090 GN=Pdzk1 PE=1 SV=1
Length=519
Score = 35.8 bits (81), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 20/63 (32%), Positives = 38/63 (60%), Gaps = 1/63 (2%)
Query 271 VRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTF 330
+ + D +I I +G AEK+GLL +GD VL ING+ + ++ +V +L+ ++T
Sbjct 26 IEKDTDGHLIRVIEEGSPAEKAGLL-DGDRVLRINGVFVDKEEHAQVVELVRKSGNSVTL 84
Query 331 VLI 333
+++
Sbjct 85 LVL 87
>sp|P42686|SRK1_SPOLA Tyrosine-protein kinase isoform SRK1 OS=Spongilla
lacustris OX=6055 GN=SRK1 PE=2 SV=1
Length=505
Score = 35.8 bits (81), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 15/39 (38%), Positives = 24/39 (62%), Gaps = 7/39 (18%)
Query 354 FDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 392
+DYD D LSF+KGD++++IS ++ +WW A
Sbjct 63 YDYDSRTDD-------DLSFKKGDLMYIISTDEGDWWFA 94
>sp|O35889|AFAD_RAT Afadin OS=Rattus norvegicus OX=10116 GN=Afdn
PE=1 SV=1
Length=1829
Score = 35.8 bits (81), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 15/53 (28%), Positives = 28/53 (53%), Gaps = 0/53 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTF 330
+ + +VKGGAA+ G L GD++L ++G + G +L++ +T
Sbjct 1042 IYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTL 1094
>sp|Q8AXV0|SH3G1_CHICK Endophilin-A2 OS=Gallus gallus OX=9031
GN=SH3GL1 PE=1 SV=1
Length=367
Score = 35.4 bits (80), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 19/54 (35%), Positives = 30/54 (56%), Gaps = 7/54 (13%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPL 403
KA +D++P +D ELG F++GDI+ + +Q D NW++ G PL
Sbjct 310 CKALYDFEPENDG-----ELG--FKEGDIITLTNQIDENWYEGMINGQSGFFPL 356
>sp|Q9ES28|ARHG7_MOUSE Rho guanine nucleotide exchange factor
7 OS=Mus musculus OX=10090 GN=Arhgef7 PE=1 SV=2
Length=862
Score = 35.8 bits (81), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 7/47 (15%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREG 396
V+A F++ ++ E LSF KGD++HV E+ WW+ G
Sbjct 168 VRAKFNFQQTN-------EDELSFSKGDVIHVTRVEEGGWWEGTHNG 207
>sp|P87378|CRK_XENLA Adapter molecule crk OS=Xenopus laevis OX=8355
GN=crk PE=2 SV=1
Length=296
Score = 35.4 bits (80), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 21/65 (32%), Positives = 35/65 (54%), Gaps = 12/65 (18%)
Query 344 KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPL 403
+E V +++A FD+ +DD +P F+KGDIL + + + WW A ED+
Sbjct 124 QEEVEYLRALFDFIGNDDEDLP-------FKKGDILRIREKPEEQWWNA-----EDSDGR 171
Query 404 AGLVP 408
G++P
Sbjct 172 RGMIP 176
>sp|Q62419|SH3G1_MOUSE Endophilin-A2 OS=Mus musculus OX=10090
GN=Sh3gl1 PE=1 SV=1
Length=368
Score = 35.4 bits (80), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 22/74 (30%), Positives = 40/74 (54%), Gaps = 11/74 (15%)
Query 331 VLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW 390
+ +PS+ + PP + KA +D++P +D ELG F++GD++ + +Q D NW+
Sbjct 296 IRMPSKSM--PPLDQP--SCKALYDFEPEND-----GELG--FREGDLITLTNQIDENWY 344
Query 391 QAYREGDEDNQPLA 404
+ G PL+
Sbjct 345 EGMLHGQSGFFPLS 358
>sp|Q557J6|DBNL_DICDI Drebrin-like protein OS=Dictyostelium discoideum
OX=44689 GN=abpE-1 PE=2 SV=1
Length=481
Score = 35.4 bits (80), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 17/46 (37%), Positives = 27/46 (59%), Gaps = 8/46 (17%)
Query 348 IHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPN-WWQA 392
+ KA +DY+ +D LSF++GDI+ ++ Q DP+ WWQ
Sbjct 425 LQAKALYDYNGEND-------GDLSFREGDIITILDQSDPDGWWQG 463
>sp|Q99L88|SNTB1_MOUSE Beta-1-syntrophin OS=Mus musculus OX=10090
GN=Sntb1 PE=1 SV=4
Length=537
Score = 35.4 bits (80), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 16/44 (36%), Positives = 28/44 (64%), Gaps = 0/44 (0%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
++IS+I KG AA+++ L+ GD +L +NG ++R +E L
Sbjct 136 ILISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQAL 179
>sp|Q92783|STAM1_HUMAN Signal transducing adapter molecule 1 OS=Homo
sapiens OX=9606 GN=STAM PE=1 SV=3
Length=540
Score = 35.4 bits (80), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 14/43 (33%), Positives = 26/43 (60%), Gaps = 7/43 (16%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 392
V+A +D++ ++D L+F+ G+I+ V+ DPNWW+
Sbjct 215 VRAIYDFEAAEDN-------ELTFKAGEIITVLDDSDPNWWKG 250
>sp|P16885|PLCG2_HUMAN 1-phosphatidylinositol 4,5-bisphosphate
phosphodiesterase gamma-2 OS=Homo sapiens OX=9606 GN=PLCG2
PE=1 SV=4
Length=1265
Score = 35.4 bits (80), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 39/141 (28%), Positives = 62/141 (44%), Gaps = 23/141 (16%)
Query 254 VKIVRIEK-ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHE-GDEVLEINGIEIRG 311
VK RI + R LG + E ++S K K L + E+LE +E
Sbjct 690 VKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHSLYRKMRLRYPVTPELLERYNME--- 746
Query 312 KDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGL 371
+D+N ++D+ S M+ + +I P + TV KA +DY R L
Sbjct 747 RDINSLYDV-SRMY-------VDPSEINPSMPQRTV---KALYDYKAK-------RSDEL 788
Query 372 SFQKGDILHVISQEDPNWWQA 392
SF +G ++H +S+E WW+
Sbjct 789 SFCRGALIHNVSKEPGGWWKG 809
>sp|O35964|SH3G1_RAT Endophilin-A2 OS=Rattus norvegicus OX=10116
GN=Sh3gl1 PE=1 SV=1
Length=368
Score = 35.0 bits (79), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 18/55 (33%), Positives = 31/55 (56%), Gaps = 7/55 (13%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLA 404
KA +D++P +D ELG F++GD++ + +Q D NW++ G PL+
Sbjct 311 CKALYDFEPEND-----GELG--FREGDLITLTNQIDENWYEGMLHGQSGFFPLS 358
>sp|Q810W9|WHRN_RAT Whirlin OS=Rattus norvegicus OX=10116 GN=Whrn
PE=1 SV=1
Length=920
Score = 35.4 bits (80), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 23/80 (29%), Positives = 40/80 (50%), Gaps = 7/80 (9%)
Query 253 TVKIVRIEKARD-----IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
T ++R+ K+ I GA R + ++ I +GG+A G L G +LE+NG
Sbjct 826 TSTLIRVRKSAATLGIAIEGGANTRQPLPRIVT--IQRGGSAHNCGQLKVGHVILEVNGQ 883
Query 308 EIRGKDVNEVFDLLSDMHGT 327
+RGK+ E ++++ T
Sbjct 884 TLRGKEHREAARVIAEAFKT 903
>sp|B1LBI4|DER_THESQ GTPase Der OS=Thermotoga sp. (strain RQ2)
OX=126740 GN=der PE=3 SV=1
Length=439
Score = 35.0 bits (79), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 19/52 (37%), Positives = 30/52 (58%), Gaps = 3/52 (6%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVA--GRDYHFV 531
+ ++G N G++ L ++NKE+ S +P TTR D+EV G+ Y FV
Sbjct 183 VAIVGRPNVGKSTLFNAILNKER-ALVSPIPGTTRDPVDEEVFIDGKKYVFV 233
>sp|Q6C2N2|HSE1_YARLI Class E vacuolar protein-sorting machinery
protein HSE1 OS=Yarrowia lipolytica (strain CLIB 122 / E
150) OX=284591 GN=HSE1 PE=3 SV=1
Length=685
Score = 35.4 bits (80), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 24/70 (34%), Positives = 33/70 (47%), Gaps = 9/70 (13%)
Query 340 PPPAKETVIHVKAHFDYDPSDDPYVPCRELG-LSFQKGDILHVISQEDPNWWQAYREGDE 398
P P TV VKA +D + E G LSF+KGDI+ V+ +WW+ G
Sbjct 245 PTPTVATVSRVKALYDLN--------ATEPGELSFRKGDIITVLESVFRDWWRGSLRGQV 296
Query 399 DNQPLAGLVP 408
PL ++P
Sbjct 297 GIFPLNYVMP 306
>sp|Q61085|RHPN1_MOUSE Rhophilin-1 OS=Mus musculus OX=10090 GN=Rhpn1
PE=1 SV=2
Length=643
Score = 35.0 bits (79), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
G T+R + V+I+ +V GG AE +GL EGD ++ +NG + EV L M
Sbjct 510 FGFTLRGD-SPVLIAAVVPGGQAESAGL-KEGDYIVSVNGQPCKWWKHLEVVTQLRSM 565
>sp|Q6QA76|PDZ11_PIG PDZ domain-containing protein 11 OS=Sus scrofa
OX=9823 GN=PDZD11 PE=2 SV=1
Length=140
Score = 33.5 bits (75), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 45/89 (51%), Gaps = 10/89 (11%)
Query 240 ERVYESIGQYGGETV----KIVRIEKARDIPLGATVRNEMDS---VIISRIVKGGAAEKS 292
ERVY Y E +IV ++K LG +R S + IS+++ A ++
Sbjct 29 ERVYHP--DYNNELTQFLPRIVTLKKPPGAQLGFNIRGGKASQLGIFISKVIPDSDAHRA 86
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
GL EGD+VL +N ++ + + ++ ++L
Sbjct 87 GL-QEGDQVLAVNDVDFQDIEHSKAVEIL 114
>sp|Q32LE7|PDZ11_BOVIN PDZ domain-containing protein 11 OS=Bos
taurus OX=9913 GN=PDZD11 PE=2 SV=1
Length=140
Score = 33.5 bits (75), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 45/89 (51%), Gaps = 10/89 (11%)
Query 240 ERVYESIGQYGGETV----KIVRIEKARDIPLGATVRNEMDS---VIISRIVKGGAAEKS 292
ERVY Y E +IV ++K LG +R S + IS+++ A ++
Sbjct 29 ERVYHP--DYNNELTQFLPRIVTLKKPPGAQLGFNIRGGKASQLGIFISKVIPDSDAHRA 86
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
GL EGD+VL +N ++ + + ++ ++L
Sbjct 87 GL-QEGDQVLAVNDVDFQDIEHSKAVEIL 114
>sp|Q9CZG9|PDZ11_MOUSE PDZ domain-containing protein 11 OS=Mus
musculus OX=10090 GN=Pdzd11 PE=1 SV=1
Length=140
Score = 33.5 bits (75), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 45/89 (51%), Gaps = 10/89 (11%)
Query 240 ERVYESIGQYGGETV----KIVRIEKARDIPLGATVRNEMDS---VIISRIVKGGAAEKS 292
ERVY Y E +IV ++K LG +R S + IS+++ A ++
Sbjct 29 ERVYHP--DYNNELTQFLPRIVTLKKPPGAQLGFNIRGGKASQLGIFISKVIPDSDAHRA 86
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
GL EGD+VL +N ++ + + ++ ++L
Sbjct 87 GL-QEGDQVLAVNDVDFQDIEHSKAVEIL 114
>sp|B9K8E0|DER_THENN GTPase Der OS=Thermotoga neapolitana (strain
ATCC 49049 / DSM 4359 / NBRC 107923 / NS-E) OX=309803 GN=der
PE=3 SV=1
Length=439
Score = 35.0 bits (79), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 20/52 (38%), Positives = 29/52 (56%), Gaps = 3/52 (6%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVA--GRDYHFV 531
I ++G N G++ L ++NKE+ S +P TTR D EV G+ Y FV
Sbjct 183 IAIVGRPNVGKSTLFNAILNKER-ALVSPIPGTTRDPVDDEVFIDGKKYIFV 233
>sp|Q14155|ARHG7_HUMAN Rho guanine nucleotide exchange factor
7 OS=Homo sapiens OX=9606 GN=ARHGEF7 PE=1 SV=2
Length=803
Score = 35.0 bits (79), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 7/47 (15%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREG 396
V+A F++ ++ E LSF KGD++HV E+ WW+ G
Sbjct 189 VRAKFNFQQTN-------EDELSFSKGDVIHVTRVEEGGWWEGTLNG 228
>sp|Q62420|SH3G2_MOUSE Endophilin-A1 OS=Mus musculus OX=10090
GN=Sh3gl2 PE=1 SV=2
Length=352
Score = 34.7 bits (78), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 19/65 (29%), Positives = 34/65 (52%), Gaps = 7/65 (11%)
Query 339 KPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDE 398
KPP + +A +D++P ++ ELG F++GDI+ + +Q D NW++ G
Sbjct 284 KPPGVQMDQPCCRALYDFEPENEG-----ELG--FKEGDIITLTNQIDENWYEGMLHGQS 336
Query 399 DNQPL 403
P+
Sbjct 337 GFFPI 341
>sp|F1LRS8|CD2AP_RAT CD2-associated protein OS=Rattus norvegicus
OX=10116 GN=Cd2ap PE=1 SV=2
Length=637
Score = 35.0 bits (79), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 15/39 (38%), Positives = 24/39 (62%), Gaps = 2/39 (5%)
Query 362 PYVPCRELGLSFQKGDILHVISQE--DPNWWQAYREGDE 398
PY E L+F++G+I+H+IS+E + WW+ G E
Sbjct 279 PYTGTNEDELTFREGEIIHLISKETGEAGWWKGELNGKE 317
>sp|Q0P5E6|SNTA1_BOVIN Alpha-1-syntrophin OS=Bos taurus OX=9913
GN=SNTA1 PE=2 SV=1
Length=505
Score = 35.0 bits (79), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 22/69 (32%), Positives = 39/69 (57%), Gaps = 5/69 (7%)
Query 257 VRIEKARDIPLGATVR----NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
V + KA LG +++ N+M ++IS+I KG AA+++ L GD +L +NG ++
Sbjct 88 VTVRKADAGGLGISIKGGRENKMP-ILISKIFKGLAADQTEALFVGDAILSVNGEDLSSA 146
Query 313 DVNEVFDLL 321
+E +L
Sbjct 147 THDEAVQVL 155
>sp|Q7S6J4|HSE1_NEUCR Class E vacuolar protein-sorting machinery
protein hse1 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A
/ CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=hse1
PE=3 SV=1
Length=745
Score = 35.0 bits (79), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 33/130 (25%), Positives = 57/130 (44%), Gaps = 21/130 (16%)
Query 346 TVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAG 405
TV V+A +D+ VP L F+KGD++ V+ +WW +G G
Sbjct 239 TVSRVRALYDF-------VPSEPGELEFKKGDVIAVLKSVYKDWWSGSLKGK------TG 285
Query 406 LVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKND-DYDNEEIL 464
+ P ++ + + ++ +E + +++ KN +K +L N + DNEEI
Sbjct 286 IFPLNYVEKLADPTPEELQ--REAQMEAEVFAEIKNVEKLLTLLSAGNTGPREEDNEEI- 342
Query 465 TYEEMSLYHQ 474
LYHQ
Sbjct 343 ----SKLYHQ 348
>sp|Q6ZMN7|PZRN4_HUMAN PDZ domain-containing RING finger protein
4 OS=Homo sapiens OX=9606 GN=PDZRN4 PE=1 SV=3
Length=1036
Score = 35.0 bits (79), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 5/91 (5%)
Query 252 ETVKIVRIEKARDIPLGATVRN---EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIE 308
E V++ R+ + L R E + +S + A K G + EGD +L+ING +
Sbjct 401 EEVELCRVSSQEKLGLTVCYRTDDEEDTGIYVSEVDPNSIAAKDGRIREGDRILQINGED 460
Query 309 IRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
++ ++ E LLS+ +L+ +I+
Sbjct 461 VQNRE--EAVALLSNDECKRIVLLVARPEIQ 489
>sp|Q13424|SNTA1_HUMAN Alpha-1-syntrophin OS=Homo sapiens OX=9606
GN=SNTA1 PE=1 SV=1
Length=505
Score = 34.7 bits (78), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 22/69 (32%), Positives = 39/69 (57%), Gaps = 5/69 (7%)
Query 257 VRIEKARDIPLGATVR----NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
V + KA LG +++ N+M ++IS+I KG AA+++ L GD +L +NG ++
Sbjct 88 VTVRKADAGGLGISIKGGRENKM-PILISKIFKGLAADQTEALFVGDAILSVNGEDLSSA 146
Query 313 DVNEVFDLL 321
+E +L
Sbjct 147 THDEAVQVL 155
>sp|Q8CIH5|PLCG2_MOUSE 1-phosphatidylinositol 4,5-bisphosphate
phosphodiesterase gamma-2 OS=Mus musculus OX=10090 GN=Plcg2
PE=1 SV=1
Length=1265
Score = 35.0 bits (79), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 38/141 (27%), Positives = 62/141 (44%), Gaps = 23/141 (16%)
Query 254 VKIVRIEK-ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHE-GDEVLEINGIEIRG 311
VK RI + R LG + E ++S K K L + E+LE +E
Sbjct 690 VKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHALYRKMRLRYPVTPELLERYNME--- 746
Query 312 KDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGL 371
+D+N ++D+ S M+ + +I P + TV KA +DY R L
Sbjct 747 RDINSLYDV-SRMY-------VDPSEINPSMPQRTV---KALYDYKAK-------RSDEL 788
Query 372 SFQKGDILHVISQEDPNWWQA 392
+F +G ++H +S+E WW+
Sbjct 789 TFCRGALIHNVSKEPGGWWKG 809
>sp|Q9JLQ0|CD2AP_MOUSE CD2-associated protein OS=Mus musculus
OX=10090 GN=Cd2ap PE=1 SV=3
Length=637
Score = 34.7 bits (78), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 15/39 (38%), Positives = 24/39 (62%), Gaps = 2/39 (5%)
Query 362 PYVPCRELGLSFQKGDILHVISQE--DPNWWQAYREGDE 398
PY E L+F++G+I+H+IS+E + WW+ G E
Sbjct 279 PYTGTNEDELTFREGEIIHLISKETGEAGWWKGELNGKE 317
>sp|P24135|PLCG2_RAT 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
gamma-2 OS=Rattus norvegicus OX=10116 GN=Plcg2
PE=1 SV=1
Length=1265
Score = 35.0 bits (79), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 38/141 (27%), Positives = 62/141 (44%), Gaps = 23/141 (16%)
Query 254 VKIVRIEK-ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHE-GDEVLEINGIEIRG 311
VK RI + R LG + E ++S K K L + E+LE +E
Sbjct 690 VKHCRINRDGRHFVLGTSAYFESLVELVSYYEKHALYRKMRLRYPVTPELLERYNME--- 746
Query 312 KDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGL 371
+D+N ++D+ S M+ + +I P + TV KA +DY R L
Sbjct 747 RDINSLYDV-SRMY-------VDPSEINPSMPQRTV---KALYDYKAK-------RSDEL 788
Query 372 SFQKGDILHVISQEDPNWWQA 392
+F +G ++H +S+E WW+
Sbjct 789 TFCRGALIHNVSKEPGGWWKG 809
>sp|Q64434|PTK6_MOUSE Protein-tyrosine kinase 6 OS=Mus musculus
OX=10090 GN=Ptk6 PE=1 SV=1
Length=451
Score = 34.7 bits (78), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 22/57 (39%), Positives = 30/57 (53%), Gaps = 8/57 (14%)
Query 371 LSFQKGDILHVISQEDPNWWQAYREGDEDNQPLA-GLVPGKSFQQQREAMKQTIEED 426
LSFQ GD+LHV +E+ WW D + + LA G VP A K+T+E +
Sbjct 27 LSFQAGDLLHVTKKEELWWWATLL--DAEGKALAEGYVPHNYL-----AEKETVESE 76
>sp|P38753|HSE1_YEAST Class E vacuolar protein-sorting machinery
protein HSE1 OS=Saccharomyces cerevisiae (strain ATCC 204508
/ S288c) OX=559292 GN=HSE1 PE=1 SV=1
Length=452
Score = 34.7 bits (78), Expect = 3.3, Method: Compositional matrix adjust.
Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 7/67 (10%)
Query 342 PAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQ 401
PA+ V V+A +D +++P LSF+KGD++ V+ Q +WW+ G+
Sbjct 214 PAQTVVRRVRALYDLT-TNEPD------ELSFRKGDVITVLEQVYRDWWKGALRGNMGIF 266
Query 402 PLAGLVP 408
PL + P
Sbjct 267 PLNYVTP 273
>sp|Q9UPQ7|PZRN3_HUMAN E3 ubiquitin-protein ligase PDZRN3 OS=Homo
sapiens OX=9606 GN=PDZRN3 PE=1 SV=2
Length=1066
Score = 34.7 bits (78), Expect = 3.3, Method: Compositional matrix adjust.
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 7/61 (11%)
Query 267 LGATVRNEMD-----SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
LG TV D + IS I A K G + EGD +++INGIE++ ++ E LL
Sbjct 431 LGLTVCYRTDDEDDIGIYISEIDPNSIAAKDGRIREGDRIIQINGIEVQNRE--EAVALL 488
Query 322 S 322
+
Sbjct 489 T 489
>sp|O00560|SDCB1_HUMAN Syntenin-1 OS=Homo sapiens OX=9606 GN=SDCBP
PE=1 SV=1
Length=298
Score = 34.3 bits (77), Expect = 3.3, Method: Compositional matrix adjust.
Identities = 19/56 (34%), Positives = 33/56 (59%), Gaps = 1/56 (2%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
I+ IVK +A ++GLL E + EING + G +++ D+LS +T ++P+
Sbjct 218 ITSIVKDSSAARNGLLTE-HNICEINGQNVIGLKDSQIADILSTSGTVVTITIMPA 272
>sp|Q69ZS0|PZRN3_MOUSE E3 ubiquitin-protein ligase PDZRN3 OS=Mus
musculus OX=10090 GN=Pdzrn3 PE=1 SV=3
Length=1063
Score = 34.7 bits (78), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 7/61 (11%)
Query 267 LGATVRNEMD-----SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
LG TV D + IS I A K G + EGD +++INGIE++ ++ E LL
Sbjct 431 LGLTVCYRTDDEDDIGIYISEIDPNSIAAKDGRIREGDRIIQINGIEVQNRE--EAVALL 488
Query 322 S 322
+
Sbjct 489 T 489
>sp|Q99963|SH3G3_HUMAN Endophilin-A3 OS=Homo sapiens OX=9606 GN=SH3GL3
PE=1 SV=1
Length=347
Score = 34.3 bits (77), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 25/89 (28%), Positives = 37/89 (42%), Gaps = 20/89 (22%)
Query 333 IPSQQIKPPPAK---------ETVIHVKAHFDYDPSDDPYVPCRELG---------LSFQ 374
+P ++ KP P K T VK P D P CR L L F+
Sbjct 250 VPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPC--CRGLYDFEPENQGELGFK 307
Query 375 KGDILHVISQEDPNWWQAYREGDEDNQPL 403
+GDI+ + +Q D NW++ G+ P+
Sbjct 308 EGDIITLTNQIDENWYEGMIHGESGFFPI 336
>sp|P68907|PZRN3_RAT E3 ubiquitin-protein ligase PDZRN3 OS=Rattus
norvegicus OX=10116 GN=Pdzrn3 PE=1 SV=1
Length=1062
Score = 34.7 bits (78), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 7/61 (11%)
Query 267 LGATVRNEMD-----SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
LG TV D + IS I A K G + EGD +++INGIE++ ++ E LL
Sbjct 430 LGLTVCYRTDDEDDIGIYISEIDPNSIAAKDGRIREGDRIIQINGIEVQNRE--EAVALL 487
Query 322 S 322
+
Sbjct 488 T 488
>sp|B7IE34|DER_THEAB GTPase Der OS=Thermosipho africanus (strain
TCF52B) OX=484019 GN=der PE=3 SV=1
Length=439
Score = 34.3 bits (77), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 3/50 (6%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVA--GRDYHFV 531
IG N G++ L ++NKE+ + +P TTR D+ V GR Y FV
Sbjct 186 FIGRPNAGKSTLFNSILNKER-VLVTPIPGTTRDSVDELVTINGRKYLFV 234
>sp|P62484|ABI2_MOUSE Abl interactor 2 OS=Mus musculus OX=10090
GN=Abi2 PE=1 SV=1
Length=446
Score = 34.3 bits (77), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 6/47 (13%)
Query 363 YVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
Y +E LSFQ+G I++VI + D W++ G + GL PG
Sbjct 395 YTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNG------VTGLFPG 435
>sp|A1ZAY1|DLISH_DROME SH3 domain-containing protein Dlish OS=Drosophila
melanogaster OX=7227 GN=Dlish PE=1 SV=1
Length=355
Score = 34.3 bits (77), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 17/53 (32%), Positives = 30/53 (57%), Gaps = 4/53 (8%)
Query 371 LSFQKGDILHVISQEDPNW-WQAYREGDEDNQPLAGLVPGKS---FQQQREAM 419
LS ++G+ + V+++EDP+W W +G E P + + P S QQQ+ +
Sbjct 202 LSVERGEFVTVLNREDPDWFWIMRSDGQEGFVPASFIYPADSVRVLQQQKATL 254
>sp|O88888|APBA3_MOUSE Amyloid-beta A4 precursor protein-binding
family A member 3 OS=Mus musculus OX=10090 GN=Apba3 PE=1
SV=1
Length=571
Score = 34.3 bits (77), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 22/85 (26%), Positives = 37/85 (44%), Gaps = 6/85 (7%)
Query 275 MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP 334
+ + +I+ ++ GG AE+ G L GD V ING + G + + ++ + L
Sbjct 415 LPTAVIANLLHGGPAERCGALSIGDRVTAINGTSLVGLSLAACQAAVREVRRLSSVTL-- 472
Query 335 SQQIKPPPAKETVI---HVKAHFDY 356
I PP VI HV+ +
Sbjct 473 -SIIHCPPVTTAVIRRPHVREQLGF 496
>sp|P27447|YES_XIPHE Tyrosine-protein kinase Yes OS=Xiphophorus
hellerii OX=8084 GN=yes PE=2 SV=3
Length=544
Score = 34.3 bits (77), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 41/95 (43%), Gaps = 15/95 (16%)
Query 340 PPPAKET--VIHVKAHFDYDP--SDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA--Y 393
P PA T V A +DY+ SDD LSF+KGD +I+ + +WW+A
Sbjct 85 PFPAVITGGVTFFVALYDYEARTSDD---------LSFRKGDRFQIINNTEGDWWEARSI 135
Query 394 REGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKE 428
G+ P + P S Q + + +D E
Sbjct 136 NTGENGYIPSNYVAPADSIQSEEWYFGKLSRKDTE 170
>sp|O43586|PPIP1_HUMAN Proline-serine-threonine phosphatase-interacting
protein 1 OS=Homo sapiens OX=9606 GN=PSTPIP1 PE=1
SV=1
Length=416
Score = 34.3 bits (77), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 27/80 (34%), Positives = 36/80 (45%), Gaps = 14/80 (18%)
Query 330 FVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNW 389
+ I Q+I+ PA +A +DY + +P EL LS GDIL VI + + W
Sbjct 345 YTAIAVQEIQGNPAS-PAQEYRALYDY-TAQNP----DELDLS--AGDILEVILEGEDGW 396
Query 390 WQAYREGDEDNQPLAGLVPG 409
W R G G VPG
Sbjct 397 WTVERNGQR------GFVPG 410
>sp|Q10199|IMP2_SCHPO Septation protein imp2 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=imp2 PE=1
SV=1
Length=670
Score = 34.3 bits (77), Expect = 4.4, Method: Compositional matrix adjust.
Identities = 16/51 (31%), Positives = 29/51 (57%), Gaps = 7/51 (14%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDED 399
+V A +DYD + +P +SF+KGD + V+ + WW+ + G++D
Sbjct 611 YVSALYDYDAA----IPEE---ISFRKGDTIAVLKLYEDGWWEGFVVGEDD 654
>sp|Q865P3|NHRF3_RABIT Na(+)/H(+) exchange regulatory cofactor
NHE-RF3 OS=Oryctolagus cuniculus OX=9986 GN=PDZK1 PE=1 SV=1
Length=518
Score = 34.3 bits (77), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 19/55 (35%), Positives = 33/55 (60%), Gaps = 1/55 (2%)
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
++ I KG AEK+GL +GD VL ING+ + ++ +V DL+ +T +++
Sbjct 34 LVRVIEKGSPAEKAGL-QDGDRVLRINGVFVDKEEHMQVVDLVRKSGNAVTLLVL 87
>sp|O35002|CTPB_BACSU Carboxy-terminal processing protease CtpB
OS=Bacillus subtilis (strain 168) OX=224308 GN=ctpB PE=1 SV=1
Length=480
Score = 33.9 bits (76), Expect = 4.9, Method: Compositional matrix adjust.
Identities = 21/49 (43%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVN 315
+GA V E +II K AEK+GL DE++ ING + GKD+N
Sbjct 114 IGAEVGMEDGKIIIVSPFKKSPAEKAGL-KPNDEIISINGESMAGKDLN 161
>sp|F4KHG6|CTPA1_ARATH Carboxyl-terminal-processing peptidase
1, chloroplastic OS=Arabidopsis thaliana OX=3702 GN=CTPA1 PE=1
SV=1
Length=489
Score = 33.9 bits (76), Expect = 5.0, Method: Compositional matrix adjust.
Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 3/67 (4%)
Query 283 IVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPP 342
+V AA+ +G+ +GDE+L +NG+++ GK EV LL + TFV++ + K P
Sbjct 221 LVLDSAADIAGV-KQGDEILAVNGMDVSGKSSFEVSSLL--QGPSKTFVVLKVKHGKCGP 277
Query 343 AKETVIH 349
K I
Sbjct 278 VKSLKIQ 284
>sp|O35180|SH3G3_RAT Endophilin-A3 OS=Rattus norvegicus OX=10116
GN=Sh3gl3 PE=1 SV=2
Length=347
Score = 33.9 bits (76), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 17/53 (32%), Positives = 27/53 (51%), Gaps = 7/53 (13%)
Query 358 PSDDP-------YVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPL 403
PSD P + P E L F++GDI+ + +Q D NW++ G+ P+
Sbjct 284 PSDQPCCRGLYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLRGESGFFPI 336
>sp|Q45670|THES_BACSJ Thermophilic serine proteinase OS=Bacillus
sp. (strain AK1) OX=268807 PE=1 SV=1
Length=401
Score = 33.9 bits (76), Expect = 5.3, Method: Compositional matrix adjust.
Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 2/50 (4%)
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNS 646
+A P L ALLA +G+N E+R+ IE+T + G YF +NS
Sbjct 348 MASPHVAGLAALLASQGRNNI--EIRQAIEQTADKISGTGTYFKYGRINS 395
>sp|Q6ZWJ1|STXB4_HUMAN Syntaxin-binding protein 4 OS=Homo sapiens
OX=9606 GN=STXBP4 PE=1 SV=2
Length=553
Score = 33.9 bits (76), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 26/98 (27%), Positives = 43/98 (44%), Gaps = 7/98 (7%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS---- 322
LG RNE V I I+ GG K G L GD+++ +N + G E +++
Sbjct 36 LGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSIITGAKL 95
Query 323 --DMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDP 358
+ + F+ S I+P T + ++A +Y P
Sbjct 96 RLESAWEIAFIRQKSDNIQPENLSCTSL-IEASGEYGP 132
>sp|A5IKF4|MNME_THEP1 tRNA modification GTPase MnmE OS=Thermotoga
petrophila (strain ATCC BAA-488 / DSM 13995 / JCM 10881
/ RKU-1) OX=390874 GN=mnmE PE=3 SV=1
Length=450
Score = 33.9 bits (76), Expect = 5.5, Method: Compositional matrix adjust.
Identities = 16/54 (30%), Positives = 30/54 (56%), Gaps = 1/54 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
NR ++++G N G++ L RL+N+++ + +P TTR +E+ R F
Sbjct 209 NRGFRMVIVGKPNVGKSTLLNRLLNEDR-AIVTDIPGTTRDVISEEIVIRGILF 261
>sp|Q9NYB9|ABI2_HUMAN Abl interactor 2 OS=Homo sapiens OX=9606
GN=ABI2 PE=1 SV=1
Length=513
Score = 33.9 bits (76), Expect = 5.5, Method: Compositional matrix adjust.
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 6/39 (15%)
Query 371 LSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
LSFQ+G I++VI + D W++ G + GL PG
Sbjct 470 LSFQEGAIIYVIKKNDDGWYEGVMNG------VTGLFPG 502
>sp|B1L9N6|MNME_THESQ tRNA modification GTPase MnmE OS=Thermotoga
sp. (strain RQ2) OX=126740 GN=mnmE PE=3 SV=1
Length=450
Score = 33.9 bits (76), Expect = 5.6, Method: Compositional matrix adjust.
Identities = 16/54 (30%), Positives = 30/54 (56%), Gaps = 1/54 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
NR ++++G N G++ L RL+N+++ + +P TTR +E+ R F
Sbjct 209 NRGLRMVIVGKPNVGKSTLLNRLLNEDR-AIVTDIPGTTRDVISEEIVIRGILF 261
>sp|Q80TH2|ERBIN_MOUSE Erbin OS=Mus musculus OX=10090 GN=Erbin
PE=1 SV=3
Length=1402
Score = 34.3 bits (77), Expect = 5.6, Method: Compositional matrix adjust.
Identities = 16/66 (24%), Positives = 31/66 (47%), Gaps = 2/66 (3%)
Query 268 GATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGT 327
G R + D + ++R+ G A K LL GD++++ NG + + LL H
Sbjct 1334 GNPFRPDDDGIFVTRVQPEGPASK--LLQPGDKIIQANGYSFINIEHGQAVSLLKTFHNA 1391
Query 328 LTFVLI 333
+ +++
Sbjct 1392 VDLIIV 1397
>sp|Q9WYA4|MNME_THEMA tRNA modification GTPase MnmE OS=Thermotoga
maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC
100826 / MSB8) OX=243274 GN=mnmE PE=1 SV=1
Length=450
Score = 33.9 bits (76), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 16/54 (30%), Positives = 30/54 (56%), Gaps = 1/54 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
NR ++++G N G++ L RL+N+++ + +P TTR +E+ R F
Sbjct 209 NRGLRMVIVGKPNVGKSTLLNRLLNEDR-AIVTDIPGTTRDVISEEIVIRGILF 261
>sp|Q6BNP6|HSE1_DEBHA Class E vacuolar protein-sorting machinery
protein HSE1 OS=Debaryomyces hansenii (strain ATCC 36239
/ CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) OX=284592
GN=HSE1 PE=3 SV=2
Length=512
Score = 33.9 bits (76), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 22/76 (29%)
Query 324 MHGTLTFVLIPSQQIKPPPAKE----TVIHVKAHFD---YDPSDDPYVPCRELGLSFQKG 376
MH T T QQ PA+ TV V+A +D Y+P + LSF+KG
Sbjct 235 MHSTPT-----GQQSTQSPAESQTIATVSKVRALYDLISYEPDE----------LSFRKG 279
Query 377 DILHVISQEDPNWWQA 392
DI+ VI +WW+
Sbjct 280 DIITVIESVYRDWWRG 295
>sp|Q24008|INAD_DROME Inactivation-no-after-potential D protein
OS=Drosophila melanogaster OX=7227 GN=inaD PE=1 SV=2
Length=674
Score = 33.9 bits (76), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 33/126 (26%), Positives = 50/126 (40%), Gaps = 16/126 (13%)
Query 246 IGQYG--GETVKIVRIEKARDIPLG-ATVRNEM--------DSVIISRIVKGGAAEKSGL 294
+G+ G GE + +V ++K G VR E+ + I IV A G
Sbjct 5 LGKQGTAGELIHMVTLDKTGKKSFGICIVRGEVKDSPNTKTTGIFIKGIVPDSPAHLCGR 64
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTL-----TFVLIPSQQIKPPPAKETVIH 349
L GD +L +NG ++R V DL+ + + TF QQ K P +
Sbjct 65 LKVGDRILSLNGKDVRNSTEQAVIDLIKEADFKIELEIQTFDKSDEQQAKSDPRSNGYMQ 124
Query 350 VKAHFD 355
K F+
Sbjct 125 AKNKFN 130
>sp|Q93646|SNT1_CAEEL Syntrophin-1 OS=Caenorhabditis elegans OX=6239
GN=stn-1 PE=1 SV=1
Length=440
Score = 33.5 bits (75), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 18/55 (33%), Positives = 33/55 (60%), Gaps = 3/55 (5%)
Query 255 KIVRIEKARDIPLGATVRNEMDS---VIISRIVKGGAAEKSGLLHEGDEVLEING 306
+ VR+ K LG +++ D+ ++IS+I KG AA+++G L D ++ +NG
Sbjct 44 RTVRVVKYDGNGLGISIKGGRDNNMPIVISKIFKGMAADQAGELFLDDVIISVNG 98
>sp|Q4KLN0|SDCB2_RAT Syntenin-2 OS=Rattus norvegicus OX=10116
GN=Sdcbp2 PE=1 SV=1
Length=296
Score = 33.5 bits (75), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 1/56 (2%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
I +VKG +A ++GLL V E+NG + G ++ ++L+ +T +IP+
Sbjct 216 IVSVVKGSSAARNGLLTN-HYVCEVNGQNVIGLKDKKIIEILTTAGNVITLTIIPT 270
>sp|Q61234|SNTA1_MOUSE Alpha-1-syntrophin OS=Mus musculus OX=10090
GN=Snta1 PE=1 SV=1
Length=503
Score = 33.5 bits (75), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 20/68 (29%), Positives = 37/68 (54%), Gaps = 3/68 (4%)
Query 257 VRIEKARDIPLGATVRNEMDS---VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
V + KA LG +++ ++ ++IS+I KG AA+++ L GD +L +NG ++
Sbjct 82 VTVRKADAGGLGISIKGGRENKMPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSAT 141
Query 314 VNEVFDLL 321
+E L
Sbjct 142 HDEAVQAL 149
>sp|Q28626|SNTA1_RABIT Alpha-1-syntrophin OS=Oryctolagus cuniculus
OX=9986 GN=SNTA1 PE=1 SV=1
Length=505
Score = 33.5 bits (75), Expect = 6.9, Method: Compositional matrix adjust.
Identities = 20/68 (29%), Positives = 37/68 (54%), Gaps = 3/68 (4%)
Query 257 VRIEKARDIPLGATVRNEMDS---VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
V + KA LG +++ ++ ++IS+I KG AA+++ L GD +L +NG ++
Sbjct 88 VTVRKADAGGLGISIKGGRENKMPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSAT 147
Query 314 VNEVFDLL 321
+E L
Sbjct 148 HDEAVQAL 155
>sp|Q9NHC3|CED2_CAEEL Cell death abnormality protein 2 OS=Caenorhabditis
elegans OX=6239 GN=ced-2 PE=1 SV=1
Length=279
Score = 33.1 bits (74), Expect = 6.9, Method: Compositional matrix adjust.
Identities = 17/51 (33%), Positives = 27/51 (53%), Gaps = 5/51 (10%)
Query 367 RELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQRE 417
RE L F++G+ L ++S+ + +WW+A + GLVP Q Q E
Sbjct 131 RETDLPFEQGERLEILSKTNQDWWEA-----RNALGTTGLVPANYVQIQME 176
>sp|Q9ES67|ARHGB_RAT Rho guanine nucleotide exchange factor 11
OS=Rattus norvegicus OX=10116 GN=Arhgef11 PE=1 SV=1
Length=1527
Score = 33.9 bits (76), Expect = 7.1, Method: Compositional matrix adjust.
Identities = 18/55 (33%), Positives = 31/55 (56%), Gaps = 2/55 (4%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL-SDMHGTLTFV 331
V++ + GGAA K+G+ EGD ++++NG + EV L+ S + LT +
Sbjct 84 VLVQSVRPGGAAMKAGV-KEGDRIIKVNGTMVTNSSHLEVVKLIKSGAYAALTLL 137
>sp|Q7SI59|CWC25_NEUCR Pre-mRNA-splicing factor cwc25 OS=Neurospora
crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 /
DSM 1257 / FGSC 987) OX=367110 GN=msp-6 PE=3 SV=1
Length=444
Score = 33.5 bits (75), Expect = 7.6, Method: Compositional matrix adjust.
Identities = 32/120 (27%), Positives = 56/120 (47%), Gaps = 13/120 (11%)
Query 111 VLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLL------QLVQNKDFQNAFK 164
LE+ KI +E ++S Q S E + LL +L+Q+ D + A
Sbjct 56 ALEAAGGKRKIDRVEWMYSGPTDGQA----GDSAETEAYLLGKRRIDKLLQDNDTKKALS 111
Query 165 IHNAITVHMNKASPPFPLISNAQDLAQEV-QTVLKPVHHKEGQELTALLNTPHIQALLLA 223
+ V A+ P P+++NA+D+A ++ + L + +E Q A++N P + LLA
Sbjct 112 KQSQQDVL--SAAGPAPVVTNARDVATKIREDPLLAIKRQEQQAYEAMMNDPIKRRQLLA 169
>sp|O70263|LNX1_MOUSE E3 ubiquitin-protein ligase LNX OS=Mus musculus
OX=10090 GN=Lnx1 PE=1 SV=1
Length=728
Score = 33.5 bits (75), Expect = 7.7, Method: Compositional matrix adjust.
Identities = 15/34 (44%), Positives = 21/34 (62%), Gaps = 0/34 (0%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
V I ++ GG A++ G L E D VL ING ++R
Sbjct 409 GVFIFNVLNGGVADRHGQLEENDRVLAINGHDLR 442
>sp|Q5BBL4|HSE1_EMENI Class E vacuolar protein-sorting machinery
protein hse1 OS=Emericella nidulans (strain FGSC A4 / ATCC
38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=hse1 PE=3
SV=1
Length=581
Score = 33.5 bits (75), Expect = 7.8, Method: Compositional matrix adjust.
Identities = 20/59 (34%), Positives = 29/59 (49%), Gaps = 9/59 (15%)
Query 346 TVIHVKAHFDYDPSDDPYVPCRELG-LSFQKGDILHVISQEDPNWWQAYREGDEDNQPL 403
TV V+A +D+ PS E G L F+KGD++ V+ +WW+ G PL
Sbjct 216 TVSRVRALYDFQPS--------EPGELQFRKGDVIAVLESVYKDWWKGSLRGQTGIFPL 266
>sp|Q86UT5|NHRF4_HUMAN Na(+)/H(+) exchange regulatory cofactor
NHE-RF4 OS=Homo sapiens OX=9606 GN=NHERF4 PE=1 SV=2
Length=571
Score = 33.5 bits (75), Expect = 7.9, Method: Compositional matrix adjust.
Identities = 14/36 (39%), Positives = 25/36 (69%), Gaps = 1/36 (3%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
+ IS++ GG+A ++GL GD +LE+NG + G++
Sbjct 491 LFISQVTPGGSAARAGL-QVGDVILEVNGYPVGGQN 525
>sp|O17583|LIN10_CAEEL Protein lin-10 OS=Caenorhabditis elegans
OX=6239 GN=lin-10 PE=1 SV=1
Length=982
Score = 33.5 bits (75), Expect = 8.0, Method: Compositional matrix adjust.
Identities = 18/73 (25%), Positives = 38/73 (52%), Gaps = 5/73 (7%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
LG +V+N +I +++GG AE+ G+ G ++EING + + + ++L+ G
Sbjct 904 LGFSVQNG----VICSLLRGGIAERGGI-RVGHRIIEINGTSVVAVAHDRIVNMLATAVG 958
Query 327 TLTFVLIPSQQIK 339
+ +P+ +
Sbjct 959 EIHMKTMPTSMFR 971
>sp|Q14511|CASL_HUMAN Enhancer of filamentation 1 OS=Homo sapiens
OX=9606 GN=NEDD9 PE=1 SV=1
Length=834
Score = 33.5 bits (75), Expect = 9.1, Method: Compositional matrix adjust.
Identities = 42/178 (24%), Positives = 67/178 (38%), Gaps = 37/178 (21%)
Query 371 LSFQKGDILHVISQEDP---NWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDK 427
L+F+KGDIL VI Q WW G + G+VPG + M++T +
Sbjct 22 LAFRKGDILTVIEQNTGGLEGWWLCSLHGRQ------GIVPGNRVKLLIGPMQETASSHE 75
Query 428 EPEKSG---------KLWCAKKNKKKRKKVLYNANKNDDYDNEEILTY------EEMSLY 472
+P SG KL+ + + +Y + Y N+ I +E +Y
Sbjct 76 QP-ASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVPPS--YQNQGIYQVPTGHGTQEQEVY 132
Query 473 HQPANRKRPI----------ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRD 520
P + +R I +I P G + + +KD + HTT+ D
Sbjct 133 QVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQKDVYDIPPSHTTQGVYD 190
>sp|Q8IVF5|TIAM2_HUMAN Rho guanine nucleotide exchange factor
TIAM2 OS=Homo sapiens OX=9606 GN=TIAM2 PE=2 SV=4
Length=1701
Score = 33.5 bits (75), Expect = 9.1, Method: Compositional matrix adjust.
Identities = 23/99 (23%), Positives = 43/99 (43%), Gaps = 11/99 (11%)
Query 254 VKIVRIEKARDIPLGATV----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
V++ + D T R + + IS ++ G A GL +G+E++ +NG +
Sbjct 891 VQLTKTGSVCDFGFAVTAQVDERQHLSRIFISDVLPDGLAYGEGL-RKGNEIMTLNGEAV 949
Query 310 RGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVI 348
D+ ++ L S+ LT + +PP K T+
Sbjct 950 SDLDLKQMEALFSEKSVGLTLI------ARPPDTKATLC 982
>sp|P53671|LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapiens OX=9606
GN=LIMK2 PE=1 SV=1
Length=638
Score = 33.1 bits (74), Expect = 9.2, Method: Compositional matrix adjust.
Identities = 16/38 (42%), Positives = 22/38 (58%), Gaps = 0/38 (0%)
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+H GD +LEING +R V EV D +S TL ++
Sbjct 198 IHPGDRILEINGTPVRTLRVEEVEDAISQTSQTLQLLI 235
>sp|D4ACE5|INTU_RAT Protein inturned OS=Rattus norvegicus OX=10116
GN=Intu PE=1 SV=1
Length=942
Score = 33.5 bits (75), Expect = 9.4, Method: Compositional matrix adjust.
Identities = 15/54 (28%), Positives = 31/54 (57%), Gaps = 1/54 (2%)
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL-SDMHGTLTF 330
+++ +V GG+A KSG + GD ++ +N +++ +++ V + M LTF
Sbjct 212 LVVHGLVPGGSAMKSGQVLVGDVLVAVNDVDVTSENIERVLSCIPGPMQVKLTF 265
>sp|Q9MZL3|CACB3_BOVIN Voltage-dependent L-type calcium channel
subunit beta-3 OS=Bos taurus OX=9913 GN=CACNB3 PE=2 SV=2
Length=484
Score = 33.1 bits (74), Expect = 9.5, Method: Compositional matrix adjust.
Identities = 58/293 (20%), Positives = 119/293 (41%), Gaps = 45/293 (15%)
Query 336 QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW--QAY 393
QQ++ K V+ + Y D P + G++F+ D LH+ + +WW +
Sbjct 50 QQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLV 109
Query 394 REGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNAN 453
+EG + +P Q+ E+++ ++++++ +SG + + R+ +
Sbjct 110 KEGGD-----IAFIPSP---QRLESIR--LKQEQKARRSGNP-SSLSDIGSRRSPPPSLA 158
Query 454 KNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKEKDRFASA 510
K E I Y+ + RP++L+GP G + +++ L + K RF
Sbjct 159 KQKQKQAEHIPPYDVVP-------SMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGR 211
Query 511 VPHTTRSRRDQEVAGRDY-------HFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSV 563
+ TR D +A R + R + + IA + + I+ +
Sbjct 212 I-SITRVTADLSLAKRSVLNNPGKRTIIERSSARSSIAEVQ-------------SEIERI 257
Query 564 RQVINSGKICLLSLRT-QSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKN 615
++ S ++ +L T L + L P I+F+ S + L+ L+ GK+
Sbjct 258 FELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKS 310
>sp|P40996|SCD2_SCHPO Protein scd2/ral3 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=scd2 PE=4 SV=1
Length=536
Score = 33.1 bits (74), Expect = 9.5, Method: Compositional matrix adjust.
Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 13/68 (19%)
Query 371 LSFQKGDILHVISQEDPNWWQAYREGDEDNQPLA---GLVPGKSFQQQREAMKQTIEEDK 427
+SF KGD HVI +E+ W E P A G VP F++ + +T++ ++
Sbjct 43 VSFAKGDFFHVIGRENDKAWY------EVCNPAAGTRGFVPVSHFEE----IGKTVKSER 92
Query 428 EPEKSGKL 435
+ + SG++
Sbjct 93 DSDGSGQI 100
>sp|Q9QXN0|SHRM3_MOUSE Protein Shroom3 OS=Mus musculus OX=10090
GN=Shroom3 PE=1 SV=2
Length=1986
Score = 33.5 bits (75), Expect = 9.9, Method: Compositional matrix adjust.
Identities = 23/71 (32%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query 266 PLGATVRNEMD---SVIISRIVKGGAAEK-SGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
P G T++ ++ +IIS+I +GG A+ S L GDEV+ IN + + E L+
Sbjct 36 PWGFTLKGGLERGEPLIISKIEEGGKADSVSSGLQAGDEVIHINEVAL-SSPRREAVSLV 94
Query 322 SDMHGTLTFVL 332
+ TL V+
Sbjct 95 KGSYKTLRLVV 105
Lambda K H a alpha
0.314 0.133 0.378 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 74397480300
Results from round 2
Query= sp|Q8N3R9|PALS1_HUMAN Protein PALS1 OS=Homo sapiens OX=9606 GN=PALS1
PE=1 SV=3
Length=675
Score E
Sequences producing significant alignments: (Bits) Value
Sequences used in model and found again:
sp|Q5RDQ2|PALS1_PONAB Protein PALS1 OS=Pongo abelii OX=9601 GN=PA... 919 0.0
sp|Q8N3R9|PALS1_HUMAN Protein PALS1 OS=Homo sapiens OX=9606 GN=PA... 919 0.0
sp|E2QY99|PALS1_CANLF Protein PALS1 OS=Canis lupus familiaris OX=... 915 0.0
sp|B4F7E7|PALS1_RAT Protein PALS1 OS=Rattus norvegicus OX=10116 G... 895 0.0
sp|Q9JLB2|PALS1_MOUSE Protein PALS1 OS=Mus musculus OX=10090 GN=P... 895 0.0
sp|Q8JHF4|PAL1A_DANRE Protein PALS1 OS=Danio rerio OX=7955 GN=pal... 810 0.0
sp|Q24210|CSKP_DROME Peripheral plasma membrane protein CASK OS=D... 598 0.0
sp|Q8BVD5|MPP7_MOUSE MAGUK p55 subfamily member 7 OS=Mus musculus... 593 0.0
sp|A8KBF6|MPP7_XENTR MAGUK p55 subfamily member 7 OS=Xenopus trop... 573 0.0
sp|Q6P0D7|MPP7_DANRE MAGUK p55 subfamily member 7 OS=Danio rerio ... 567 0.0
sp|Q5U2Y3|MPP7_RAT MAGUK p55 subfamily member 7 OS=Rattus norvegi... 551 0.0
sp|Q5T2T1|MPP7_HUMAN MAGUK p55 subfamily member 7 OS=Homo sapiens... 551 0.0
sp|A6QQZ7|MPP7_BOVIN MAGUK p55 subfamily member 7 OS=Bos taurus O... 547 0.0
sp|Q13368|MPP3_HUMAN MAGUK p55 subfamily member 3 OS=Homo sapiens... 533 0.0
sp|O88954|MPP3_RAT MAGUK p55 subfamily member 3 OS=Rattus norvegi... 525 3e-179
sp|O14936|CSKP_HUMAN Peripheral plasma membrane protein CASK OS=H... 536 4e-179
sp|O70589|CSKP_MOUSE Peripheral plasma membrane protein CASK OS=M... 536 4e-179
sp|Q62915|CSKP_RAT Peripheral plasma membrane protein CASK OS=Rat... 527 1e-175
sp|Q6P7F1|MPP4_MOUSE MAGUK p55 subfamily member 4 OS=Mus musculus... 511 5e-173
sp|D3ZAA9|MPP2_RAT MAGUK p55 subfamily member 2 OS=Rattus norvegi... 504 1e-171
sp|Q14168|MPP2_HUMAN MAGUK p55 subfamily member 2 OS=Homo sapiens... 503 1e-170
sp|Q9WV34|MPP2_MOUSE MAGUK p55 subfamily member 2 OS=Mus musculus... 501 2e-170
sp|Q9JLB0|PALS2_MOUSE Protein PALS2 OS=Mus musculus OX=10090 GN=P... 500 4e-170
sp|Q96JB8|MPP4_HUMAN MAGUK p55 subfamily member 4 OS=Homo sapiens... 500 7e-169
sp|O88910|MPP3_MOUSE MAGUK p55 subfamily member 3 OS=Mus musculus... 496 2e-168
sp|Q9NZW5|PALS2_HUMAN Protein PALS2 OS=Homo sapiens OX=9606 GN=PA... 489 5e-166
sp|Q17QN6|EM55_BOVIN 55 kDa erythrocyte membrane protein OS=Bos t... 458 7e-155
sp|Q00013|EM55_HUMAN 55 kDa erythrocyte membrane protein OS=Homo ... 452 2e-152
sp|Q5RDW4|EM55_PONAB 55 kDa erythrocyte membrane protein OS=Pongo... 451 6e-152
sp|A9CB74|EM55_PAPAN 55 kDa erythrocyte membrane protein OS=Papio... 449 2e-151
sp|P70290|EM55_MOUSE 55 kDa erythrocyte membrane protein OS=Mus m... 444 3e-149
sp|Q5ZJ00|EM55_CHICK 55 kDa erythrocyte membrane protein OS=Gallu... 439 3e-147
sp|P54936|LIN2_CAEEL Protein lin-2 OS=Caenorhabditis elegans OX=6... 445 2e-143
sp|Q9QYH1|MPP4_RAT MAGUK p55 subfamily member 4 OS=Rattus norvegi... 426 1e-142
sp|P49697|EM55_TAKRU 55 kDa erythrocyte membrane protein OS=Takif... 417 1e-138
sp|Q92796|DLG3_HUMAN Disks large homolog 3 OS=Homo sapiens OX=960... 415 2e-133
sp|Q62936|DLG3_RAT Disks large homolog 3 OS=Rattus norvegicus OX=... 415 5e-133
sp|P70175|DLG3_MOUSE Disks large homolog 3 OS=Mus musculus OX=100... 415 5e-133
sp|Q15700|DLG2_HUMAN Disks large homolog 2 OS=Homo sapiens OX=960... 414 1e-132
sp|Q91XM9|DLG2_MOUSE Disks large homolog 2 OS=Mus musculus OX=100... 412 1e-131
sp|Q63622|DLG2_RAT Disks large homolog 2 OS=Rattus norvegicus OX=... 410 4e-131
sp|Q5PYH7|DLG2_DANRE Disks large homolog 2 OS=Danio rerio OX=7955... 400 5e-127
sp|Q5PYH5|DLG1L_DANRE Discs large homolog 1-like protein OS=Danio... 397 2e-126
sp|Q12959|DLG1_HUMAN Disks large homolog 1 OS=Homo sapiens OX=960... 394 2e-124
sp|Q28C55|DLG1_XENTR Disks large homolog 1 OS=Xenopus tropicalis ... 394 4e-124
sp|Q811D0|DLG1_MOUSE Disks large homolog 1 OS=Mus musculus OX=100... 392 1e-123
sp|Q62696|DLG1_RAT Disks large homolog 1 OS=Rattus norvegicus OX=... 389 2e-122
sp|P31016|DLG4_RAT Disks large homolog 4 OS=Rattus norvegicus OX=... 380 5e-121
sp|P78352|DLG4_HUMAN Disks large homolog 4 OS=Homo sapiens OX=960... 380 5e-121
sp|Q62108|DLG4_MOUSE Disks large homolog 4 OS=Mus musculus OX=100... 378 2e-120
sp|P31007|DLG1_DROME Disks large 1 tumor suppressor protein OS=Dr... 379 5e-118
sp|Q6R005|DLG4_DANRE Disks large homolog 4 OS=Danio rerio OX=7955... 362 2e-113
sp|G5ECY0|DLG1_CAEEL Disks large homolog 1 OS=Caenorhabditis eleg... 347 4e-106
sp|Q5PYH6|DLG1_DANRE Disks large homolog 1 OS=Danio rerio OX=7955... 301 2e-89
sp|Q0HZX1|KGUA_SHESR Guanylate kinase OS=Shewanella sp. (strain M... 274 3e-87
sp|Q8EJU6|KGUA_SHEON Guanylate kinase OS=Shewanella oneidensis (s... 274 5e-87
sp|Q7WZE5|KGUA_SHEVD Guanylate kinase OS=Shewanella violacea (str... 273 7e-87
sp|Q0HE40|KGUA_SHESM Guanylate kinase OS=Shewanella sp. (strain M... 273 1e-86
sp|Q12IL8|KGUA_SHEDO Guanylate kinase OS=Shewanella denitrificans... 272 3e-86
sp|Q9KNM4|KGUA_VIBCH Guanylate kinase OS=Vibrio cholerae serotype... 266 8e-84
sp|Q87TA9|KGUA_VIBPA Guanylate kinase OS=Vibrio parahaemolyticus ... 264 3e-83
sp|Q7MPW9|KGUA_VIBVY Guanylate kinase OS=Vibrio vulnificus (strai... 263 1e-82
sp|Q8DDV6|KGUA_VIBVU Guanylate kinase OS=Vibrio vulnificus (strai... 263 1e-82
sp|Q9X6M5|KGUA_SALTY Guanylate kinase OS=Salmonella typhimurium (... 262 2e-82
sp|O97758|ZO1_CANLF Tight junction protein ZO-1 OS=Canis lupus fa... 288 2e-82
sp|Q088T7|KGUA_SHEFN Guanylate kinase OS=Shewanella frigidimarina... 262 2e-82
sp|Q07157|ZO1_HUMAN Tight junction protein ZO-1 OS=Homo sapiens O... 288 4e-82
sp|Q8Z2H9|KGUA_SALTI Guanylate kinase OS=Salmonella typhi OX=9037... 261 4e-82
sp|Q5PC40|KGUA_SALPA Guanylate kinase OS=Salmonella paratyphi A (... 261 4e-82
sp|Q31UQ6|KGUA_SHIBS Guanylate kinase OS=Shigella boydii serotype... 261 7e-82
sp|Q3YW11|KGUA_SHISS Guanylate kinase OS=Shigella sonnei (strain ... 260 1e-81
sp|P60548|KGUA_SHIFL Guanylate kinase OS=Shigella flexneri OX=623... 260 1e-81
sp|Q1R4U3|KGUA_ECOUT Guanylate kinase OS=Escherichia coli (strain... 260 1e-81
sp|P60546|KGUA_ECOLI Guanylate kinase OS=Escherichia coli (strain... 260 1e-81
sp|P60547|KGUA_ECOL6 Guanylate kinase OS=Escherichia coli O6:H1 (... 260 1e-81
sp|Q0TBG1|KGUA_ECOL5 Guanylate kinase OS=Escherichia coli O6:K15:... 260 1e-81
sp|P39447|ZO1_MOUSE Tight junction protein ZO-1 OS=Mus musculus O... 286 1e-81
sp|A0A0G2K2P5|ZO1_RAT Tight junction protein ZO-1 OS=Rattus norve... 286 1e-81
sp|Q57I92|KGUA_SALCH Guanylate kinase OS=Salmonella choleraesuis ... 259 3e-81
sp|Q329K8|KGUA_SHIDS Guanylate kinase OS=Shigella dysenteriae ser... 258 7e-81
sp|Q8XD88|KGUA_ECO57 Guanylate kinase OS=Escherichia coli O157:H7... 256 2e-80
sp|Q3IJH8|KGUA_PSET1 Guanylate kinase OS=Pseudoalteromonas transl... 256 3e-80
sp|Q5E8P5|KGUA_ALIF1 Guanylate kinase OS=Aliivibrio fischeri (str... 256 4e-80
sp|Q602T6|KGUA_METCA Guanylate kinase OS=Methylococcus capsulatus... 256 4e-80
sp|Q6LVP5|KGUA_PHOPR Guanylate kinase OS=Photobacterium profundum... 255 6e-80
sp|Q5QYH9|KGUA_IDILO Guanylate kinase OS=Idiomarina loihiensis (s... 255 8e-80
sp|Q3AC14|KGUA_CARHZ Guanylate kinase OS=Carboxydothermus hydroge... 255 8e-80
sp|Q65RR5|KGUA_MANSM Guanylate kinase OS=Mannheimia succiniciprod... 255 1e-79
sp|Q8TDM6|DLG5_HUMAN Disks large homolog 5 OS=Homo sapiens OX=960... 280 1e-79
sp|O34328|KGUA_BACSU Guanylate kinase OS=Bacillus subtilis (strai... 253 3e-79
sp|P44310|KGUA_HAEIN Guanylate kinase OS=Haemophilus influenzae (... 254 3e-79
sp|Q66GE5|KGUA_YERPS Guanylate kinase OS=Yersinia pseudotuberculo... 253 3e-79
sp|Q1CCZ3|KGUA_YERPN Guanylate kinase OS=Yersinia pestis bv. Anti... 253 3e-79
sp|Q8ZJQ2|KGUA_YERPE Guanylate kinase OS=Yersinia pestis OX=632 G... 253 3e-79
sp|Q1C258|KGUA_YERPA Guanylate kinase OS=Yersinia pestis bv. Anti... 253 3e-79
sp|Q0I5L8|KGUA_HISS1 Guanylate kinase OS=Histophilus somni (strai... 253 4e-79
sp|Q479A8|KGUA_DECAR Guanylate kinase OS=Dechloromonas aromatica ... 253 4e-79
sp|Q7N9P2|KGUA_PHOLL Guanylate kinase OS=Photorhabdus laumondii s... 253 4e-79
sp|O95049|ZO3_HUMAN Tight junction protein ZO-3 OS=Homo sapiens O... 273 7e-79
sp|Q2NQS9|KGUA_SODGM Guanylate kinase OS=Sodalis glossinidius (st... 253 8e-79
sp|Q15Z10|KGUA_PSEA6 Guanylate kinase OS=Pseudoalteromonas atlant... 253 8e-79
sp|Q4QJK3|KGUA_HAEI8 Guanylate kinase OS=Haemophilus influenzae (... 252 1e-78
sp|Q8K9C7|KGUA_BUCAP Guanylate kinase OS=Buchnera aphidicola subs... 251 4e-78
sp|O62683|ZO3_CANLF Tight junction protein ZO-3 OS=Canis lupus fa... 269 8e-78
sp|Q65JT0|KGUA_BACLD Guanylate kinase OS=Bacillus licheniformis (... 249 9e-78
sp|P57888|KGUA_PASMU Guanylate kinase OS=Pasteurella multocida (s... 250 9e-78
sp|E9Q9R9|DLG5_MOUSE Disks large homolog 5 OS=Mus musculus OX=100... 274 1e-77
sp|Q1QSI1|KGUA_CHRSD Guanylate kinase OS=Chromohalobacter salexig... 249 1e-77
sp|Q88C87|KGUA_PSEPK Guanylate kinase OS=Pseudomonas putida (stra... 249 2e-77
sp|Q5F775|KGUA_NEIG1 Guanylate kinase OS=Neisseria gonorrhoeae (s... 248 2e-77
sp|Q67PR9|KGUA_SYMTH Guanylate kinase OS=Symbiobacterium thermoph... 248 3e-77
sp|Q89AC8|KGUA_BUCBP Guanylate kinase OS=Buchnera aphidicola subs... 248 4e-77
sp|Q5P3M0|KGUA_AROAE Guanylate kinase OS=Aromatoleum aromaticum (... 248 4e-77
sp|Q47UB3|KGUA_COLP3 Guanylate kinase OS=Colwellia psychrerythrae... 248 4e-77
sp|Q64520|KGUA_MOUSE Guanylate kinase OS=Mus musculus OX=10090 GN... 247 7e-77
sp|Q1GNB4|KGUA_SPHAL Guanylate kinase OS=Sphingopyxis alaskensis ... 248 7e-77
sp|Q2S8R2|KGUA_HAHCH Guanylate kinase OS=Hahella chejuensis (stra... 247 9e-77
sp|Q82ZD5|KGUA_ENTFA Guanylate kinase OS=Enterococcus faecalis (s... 246 2e-76
sp|Q0A5V3|KGUA_ALKEH Guanylate kinase OS=Alkalilimnicola ehrlichi... 246 2e-76
sp|Q9JT96|KGUA_NEIMA Guanylate kinase OS=Neisseria meningitidis s... 245 6e-76
sp|Q7VKP3|KGUA_HAEDU Guanylate kinase OS=Haemophilus ducreyi (str... 245 7e-76
sp|Q7NRL1|KGUA_CHRVO Guanylate kinase OS=Chromobacterium violaceu... 245 8e-76
sp|P15454|KGUA_YEAST Guanylate kinase OS=Saccharomyces cerevisiae... 244 9e-76
sp|Q24TX4|KGUA_DESHY Guanylate kinase OS=Desulfitobacterium hafni... 244 1e-75
sp|Q8Z0I7|KGUA_NOSS1 Guanylate kinase OS=Nostoc sp. (strain PCC 7... 244 1e-75
sp|Q3K4L8|KGUA_PSEPF Guanylate kinase OS=Pseudomonas fluorescens ... 244 1e-75
sp|Q3MD38|KGUA_TRIV2 Guanylate kinase OS=Trichormus variabilis (s... 244 1e-75
sp|Q9QXY1|ZO3_MOUSE Tight junction protein ZO-3 OS=Mus musculus O... 263 1e-75
sp|Q8NX22|KGUA_STAAW Guanylate kinase OS=Staphylococcus aureus (s... 244 2e-75
sp|Q6GA04|KGUA_STAAS Guanylate kinase OS=Staphylococcus aureus (s... 244 2e-75
sp|Q5HGM3|KGUA_STAAC Guanylate kinase OS=Staphylococcus aureus (s... 244 2e-75
sp|Q2G1U0|KGUA_STAA8 Guanylate kinase OS=Staphylococcus aureus (s... 244 2e-75
sp|Q2FHM9|KGUA_STAA3 Guanylate kinase OS=Staphylococcus aureus (s... 244 2e-75
sp|Q4K3R4|KGUA_PSEF5 Guanylate kinase OS=Pseudomonas fluorescens ... 243 2e-75
sp|Q9Z0U1|ZO2_MOUSE Tight junction protein ZO-2 OS=Mus musculus O... 266 2e-75
sp|Q8DNR5|KGUA_STRR6 Guanylate kinase OS=Streptococcus pneumoniae... 243 2e-75
sp|Q1LQ34|KGUA_CUPMC Guanylate kinase OS=Cupriavidus metalliduran... 243 3e-75
sp|P99176|KGUA_STAAN Guanylate kinase OS=Staphylococcus aureus (s... 243 3e-75
sp|P65219|KGUA_STAAM Guanylate kinase OS=Staphylococcus aureus (s... 243 3e-75
sp|Q9HTM2|KGUA_PSEAE Guanylate kinase OS=Pseudomonas aeruginosa (... 243 3e-75
sp|Q8R9S6|KGUA_CALS4 Guanylate kinase OS=Caldanaerobacter subterr... 243 3e-75
sp|P57509|KGUA_BUCAI Guanylate kinase OS=Buchnera aphidicola subs... 243 3e-75
sp|Q6GHM6|KGUA_STAAR Guanylate kinase OS=Staphylococcus aureus (s... 243 4e-75
sp|Q2YXF9|KGUA_STAAB Guanylate kinase OS=Staphylococcus aureus (s... 243 4e-75
sp|Q5L0S8|KGUA_GEOKA Guanylate kinase OS=Geobacillus kaustophilus... 243 4e-75
sp|Q9JYB5|KGUA_NEIMB Guanylate kinase OS=Neisseria meningitidis s... 243 5e-75
sp|Q97PA3|KGUA_STRPN Guanylate kinase OS=Streptococcus pneumoniae... 243 5e-75
sp|Q2L090|KGUA_BORA1 Guanylate kinase OS=Bordetella avium (strain... 243 5e-75
sp|Q31DP7|KGUA_HYDCU Guanylate kinase OS=Hydrogenovibrio crunogen... 242 6e-75
sp|Q2QPW1|GMK1_ORYSJ Guanylate kinase 1 OS=Oryza sativa subsp. ja... 248 7e-75
sp|Q4L5R1|KGUA_STAHJ Guanylate kinase OS=Staphylococcus haemolyti... 242 8e-75
sp|Q2SY72|KGUA_BURTA Guanylate kinase OS=Burkholderia thailandens... 243 9e-75
sp|Q1BY73|KGUA_BURO1 Guanylate kinase OS=Burkholderia orbicola (s... 243 1e-74
sp|P60551|KGUA_GEOSL Guanylate kinase OS=Geobacter sulfurreducens... 241 1e-74
sp|P0C0M9|KGUA_STAES Guanylate kinase OS=Staphylococcus epidermid... 242 1e-74
sp|Q5HPY1|KGUA_STAEQ Guanylate kinase OS=Staphylococcus epidermid... 242 1e-74
sp|Q1WUB5|KGUA_LIGS1 Guanylate kinase OS=Ligilactobacillus saliva... 241 1e-74
sp|Q8DMQ7|KGUA_THEVB Guanylate kinase OS=Thermosynechococcus vest... 241 1e-74
sp|Q88WL7|KGUA_LACPL Guanylate kinase OS=Lactiplantibacillus plan... 241 1e-74
sp|Q5NQE8|KGUA_ZYMMO Guanylate kinase OS=Zymomonas mobilis subsp.... 241 2e-74
sp|Q3ALX6|KGUA_SYNSC Guanylate kinase OS=Synechococcus sp. (strai... 240 2e-74
sp|Q39IL2|KGUA_BURL3 Guanylate kinase OS=Burkholderia lata (strai... 242 2e-74
sp|Q95168|ZO2_CANLF Tight junction protein ZO-2 OS=Canis lupus fa... 263 2e-74
sp|Q3SLI4|KGUA_THIDA Guanylate kinase OS=Thiobacillus denitrifica... 241 2e-74
sp|Q4FQY7|KGUA_PSYA2 Guanylate kinase OS=Psychrobacter arcticus (... 241 2e-74
sp|Q5M3I4|KGUA_STRT2 Guanylate kinase OS=Streptococcus thermophil... 241 3e-74
sp|Q5LYX1|KGUA_STRT1 Guanylate kinase OS=Streptococcus thermophil... 241 3e-74
sp|Q6DB60|KGUA_PECAS Guanylate kinase OS=Pectobacterium atrosepti... 240 3e-74
sp|Q72DM9|KGUA_DESVH Guanylate kinase OS=Desulfovibrio vulgaris (... 240 4e-74
sp|Q1GXB9|KGUA_METFK Guanylate kinase OS=Methylobacillus flagella... 240 4e-74
sp|Q3A523|KGUA_SYNC1 Guanylate kinase OS=Syntrophotalea carbinoli... 240 5e-74
sp|Q38XU0|KGUA_LATSS Guanylate kinase OS=Latilactobacillus sakei ... 239 6e-74
sp|P65221|KGUA_STRA5 Guanylate kinase OS=Streptococcus agalactiae... 239 7e-74
sp|P65220|KGUA_STRA3 Guanylate kinase OS=Streptococcus agalactiae... 239 7e-74
sp|Q3K368|KGUA_STRA1 Guanylate kinase OS=Streptococcus agalactiae... 239 7e-74
sp|Q7VXZ3|KGUA_BORPE Guanylate kinase OS=Bordetella pertussis (st... 239 9e-74
sp|Q7W6B2|KGUA_BORPA Guanylate kinase OS=Bordetella parapertussis... 239 9e-74
sp|Q7WI80|KGUA_BORBR Guanylate kinase OS=Bordetella bronchiseptic... 239 9e-74
sp|Q99YM5|KGUA_STRP1 Guanylate kinase OS=Streptococcus pyogenes s... 239 1e-73
sp|Q3JBT3|KGUA_NITOC Guanylate kinase OS=Nitrosococcus oceani (st... 239 1e-73
sp|Q21EC9|KGUA_SACD2 Guanylate kinase OS=Saccharophagus degradans... 239 1e-73
sp|P0DB95|KGUA_STRPQ Guanylate kinase OS=Streptococcus pyogenes s... 239 1e-73
sp|Q48S18|KGUA_STRPM Guanylate kinase OS=Streptococcus pyogenes s... 239 1e-73
sp|Q1J5I6|KGUA_STRPF Guanylate kinase OS=Streptococcus pyogenes s... 239 1e-73
sp|Q1JFN7|KGUA_STRPD Guanylate kinase OS=Streptococcus pyogenes s... 239 1e-73
sp|Q1JKP6|KGUA_STRPC Guanylate kinase OS=Streptococcus pyogenes s... 239 1e-73
sp|Q1JAJ4|KGUA_STRPB Guanylate kinase OS=Streptococcus pyogenes s... 239 1e-73
sp|P65223|KGUA_STRP8 Guanylate kinase OS=Streptococcus pyogenes s... 239 1e-73
sp|Q5XAP1|KGUA_STRP6 Guanylate kinase OS=Streptococcus pyogenes s... 239 1e-73
sp|P0DB94|KGUA_STRP3 Guanylate kinase OS=Streptococcus pyogenes s... 239 1e-73
sp|Q0SS73|KGUA_CLOPS Guanylate kinase OS=Clostridium perfringens ... 239 1e-73
sp|Q5SI18|KGUA_THET8 Guanylate kinase OS=Thermus thermophilus (st... 239 1e-73
sp|Q0AXK8|KGUA_SYNWW Guanylate kinase OS=Syntrophomonas wolfei su... 238 1e-73
sp|Q8ER28|KGUA_OCEIH Guanylate kinase OS=Oceanobacillus iheyensis... 238 2e-73
sp|Q46YE8|KGUA_CUPPJ Guanylate kinase OS=Cupriavidus pinatubonens... 239 2e-73
sp|Q1Q973|KGUA_PSYCK Guanylate kinase OS=Psychrobacter cryohalole... 238 2e-73
sp|Q0TPK6|KGUA_CLOP1 Guanylate kinase OS=Clostridium perfringens ... 238 2e-73
sp|Q92AI1|KGUA_LISIN Guanylate kinase OS=Listeria innocua serovar... 238 2e-73
sp|Q8XJK8|KGUA_CLOPE Guanylate kinase OS=Clostridium perfringens ... 238 3e-73
sp|Q13V49|KGUA_PARXL Guanylate kinase OS=Paraburkholderia xenovor... 239 3e-73
sp|Q72ID5|KGUA_THET2 Guanylate kinase OS=Thermus thermophilus (st... 238 3e-73
sp|P60552|KGUA_LACJO Guanylate kinase OS=Lactobacillus johnsonii ... 238 4e-73
sp|Q4UK55|KGUA_RICFE Guanylate kinase OS=Rickettsia felis (strain... 237 4e-73
sp|Q92QZ2|KGUA_RHIME Guanylate kinase OS=Rhizobium meliloti (stra... 238 5e-73
sp|Q8XXF9|KGUA_RALN1 Guanylate kinase OS=Ralstonia nicotianae (st... 238 5e-73
sp|Q49WZ1|KGUA_STAS1 Guanylate kinase OS=Staphylococcus saprophyt... 237 6e-73
sp|Q3AWM1|KGUA_SYNS9 Guanylate kinase OS=Synechococcus sp. (strai... 236 7e-73
sp|Q9CEE3|KGUA_LACLA Guanylate kinase OS=Lactococcus lactis subsp... 237 7e-73
sp|Q9UDY2|ZO2_HUMAN Tight junction protein ZO-2 OS=Homo sapiens O... 259 8e-73
sp|Q6F7H0|KGUA_ACIAD Guanylate kinase OS=Acinetobacter baylyi (st... 237 9e-73
sp|P93757|GMK1_ARATH Guanylate kinase 1 OS=Arabidopsis thaliana O... 243 9e-73
sp|Q63RV7|KGUA_BURPS Guanylate kinase OS=Burkholderia pseudomalle... 237 1e-72
sp|Q3JPS9|KGUA_BURP1 Guanylate kinase OS=Burkholderia pseudomalle... 237 1e-72
sp|Q62I00|KGUA_BURMA Guanylate kinase OS=Burkholderia mallei (str... 237 1e-72
sp|Q16774|KGUA_HUMAN Guanylate kinase OS=Homo sapiens OX=9606 GN=... 236 1e-72
sp|Q182S8|KGUA_CLOD6 Guanylate kinase OS=Clostridioides difficile... 236 1e-72
sp|Q39T72|KGUA_GEOMG Guanylate kinase OS=Geobacter metallireducen... 236 2e-72
sp|Q88BE2|KGUA_PSESM Guanylate kinase OS=Pseudomonas syringae pv.... 236 2e-72
sp|Q8DVK6|KGUA_STRMU Guanylate kinase OS=Streptococcus mutans ser... 236 2e-72
sp|Q5H3S2|KGUA_XANOR Guanylate kinase OS=Xanthomonas oryzae pv. o... 235 3e-72
sp|Q2P6N0|KGUA_XANOM Guanylate kinase OS=Xanthomonas oryzae pv. o... 235 3e-72
sp|Q8P5T7|KGUA_XANCP Guanylate kinase OS=Xanthomonas campestris p... 235 3e-72
sp|Q4UY41|KGUA_XANC8 Guanylate kinase OS=Xanthomonas campestris p... 235 3e-72
sp|Q7VRJ7|KGUA_BLOFL Guanylate kinase OS=Blochmannia floridanus O... 235 4e-72
sp|Q2KA85|KGUA_RHIEC Guanylate kinase OS=Rhizobium etli (strain C... 235 5e-72
sp|Q5WV30|KGUA_LEGPL Guanylate kinase OS=Legionella pneumophila (... 234 5e-72
sp|Q9K9Y2|KGUA_HALH5 Guanylate kinase OS=Halalkalibacterium halod... 234 6e-72
sp|Q1RK99|KGUA_RICBR Guanylate kinase OS=Rickettsia bellii (strai... 234 6e-72
sp|Q135N9|KGUA_RHOPS Guanylate kinase OS=Rhodopseudomonas palustr... 234 7e-72
sp|Q9M682|GMK2_ARATH Guanylate kinase 2 OS=Arabidopsis thaliana O... 241 9e-72
sp|Q5X3P2|KGUA_LEGPA Guanylate kinase OS=Legionella pneumophila (... 234 1e-71
sp|Q8PH65|KGUA_XANAC Guanylate kinase OS=Xanthomonas axonopodis p... 234 1e-71
sp|Q895Q5|KGUA_CLOTE Guanylate kinase OS=Clostridium tetani (stra... 234 1e-71
sp|Q9P6I5|KGUA_SCHPO Guanylate kinase OS=Schizosaccharomyces pomb... 233 1e-71
sp|Q2YD10|KGUA_NITMU Guanylate kinase OS=Nitrosospira multiformis... 234 1e-71
sp|Q3BPS0|KGUA_XANC5 Guanylate kinase OS=Xanthomonas campestris p... 233 1e-71
sp|P31006|KGUA_PIG Guanylate kinase OS=Sus scrofa OX=9823 GN=GUK1... 233 1e-71
sp|Q0VT94|KGUA_ALCBS Guanylate kinase OS=Alcanivorax borkumensis ... 233 1e-71
sp|P60556|KGUA_RHOPA Guanylate kinase OS=Rhodopseudomonas palustr... 234 2e-71
sp|Q30XT1|KGUA_OLEA2 Guanylate kinase OS=Oleidesulfovibrio alaske... 233 2e-71
sp|Q7U570|KGUA_PARMW Guanylate kinase OS=Parasynechococcus mareni... 232 2e-71
sp|Q11HG8|KGUA_CHESB Guanylate kinase OS=Chelativorans sp. (strai... 234 2e-71
sp|Q6G439|KGUA_BARHE Guanylate kinase OS=Bartonella henselae (str... 234 2e-71
sp|Q5LS25|KGUA_RUEPO Guanylate kinase OS=Ruegeria pomeroyi (strai... 233 2e-71
sp|Q9ZCH7|KGUA_RICPR Guanylate kinase OS=Rickettsia prowazekii (s... 233 2e-71
sp|P46195|KGUA_BOVIN Guanylate kinase OS=Bos taurus OX=9913 GN=GU... 233 2e-71
sp|Q2IX83|KGUA_RHOP2 Guanylate kinase OS=Rhodopseudomonas palustr... 233 2e-71
sp|Q21TP7|KGUA_ALBFT Guanylate kinase OS=Albidiferax ferrireducen... 233 2e-71
sp|Q3J2A5|KGUA_CERS4 Guanylate kinase OS=Cereibacter sphaeroides ... 233 2e-71
sp|Q48Q15|KGUA_PSE14 Guanylate kinase OS=Pseudomonas savastanoi p... 233 3e-71
sp|Q0I868|KGUA_SYNS3 Guanylate kinase OS=Synechococcus sp. (strai... 232 3e-71
sp|Q5ZTZ8|KGUA_LEGPH Guanylate kinase OS=Legionella pneumophila s... 233 3e-71
sp|Q1G9H8|KGUA_LACDA Guanylate kinase OS=Lactobacillus delbruecki... 232 5e-71
sp|Q83EL7|KGUA_COXBU Guanylate kinase OS=Coxiella burnetii (strai... 232 5e-71
sp|P72648|KGUA_SYNY3 Guanylate kinase OS=Synechocystis sp. (strai... 231 6e-71
sp|Q4ZZY8|KGUA_PSEU2 Guanylate kinase OS=Pseudomonas syringae pv.... 232 6e-71
sp|Q97ID0|KGUA_CLOAB Guanylate kinase OS=Clostridium acetobutylic... 232 6e-71
sp|Q2W9C3|KGUA_MAGSA Guanylate kinase OS=Magnetospirillum magneti... 232 8e-71
sp|Q1LTY3|KGUA_BAUCH Guanylate kinase OS=Baumannia cicadellinicol... 231 1e-70
sp|Q1MRL0|KGUA_LAWIP Guanylate kinase OS=Lawsonia intracellularis... 231 2e-70
sp|Q5WFK3|KGUA_SHOC1 Guanylate kinase OS=Shouchella clausii (stra... 231 2e-70
sp|Q89MV4|KGUA_BRADU Guanylate kinase OS=Bradyrhizobium diazoeffi... 231 2e-70
sp|P65218|KGUA_BRUSU Guanylate kinase OS=Brucella suis biovar 1 (... 231 2e-70
sp|P65217|KGUA_BRUME Guanylate kinase OS=Brucella melitensis biot... 231 2e-70
sp|Q57EQ3|KGUA_BRUAB Guanylate kinase OS=Brucella abortus biovar ... 231 2e-70
sp|Q2YMJ2|KGUA_BRUA2 Guanylate kinase OS=Brucella abortus (strain... 231 2e-70
sp|Q92GC9|KGUA_RICCN Guanylate kinase OS=Rickettsia conorii (stra... 231 3e-70
sp|Q54XF2|KGUA_DICDI Guanylate kinase OS=Dictyostelium discoideum... 229 4e-70
sp|Q12DV7|KGUA_POLSJ Guanylate kinase OS=Polaromonas sp. (strain ... 230 4e-70
sp|Q2NIH1|KGUA_AYWBP Guanylate kinase OS=Aster yellows witches'-b... 229 5e-70
sp|P60554|KGUA_ONYPE Guanylate kinase OS=Onion yellows phytoplasm... 229 7e-70
sp|Q1GH67|KGUA_RUEST Guanylate kinase OS=Ruegeria sp. (strain TM1... 229 9e-70
sp|Q827Q3|KGUA_STRAW Guanylate kinase OS=Streptomyces avermitilis... 228 9e-70
sp|Q68VY3|KGUA_RICTY Guanylate kinase OS=Rickettsia typhi (strain... 228 9e-70
sp|Q6HEU4|KGUA_BACHK Guanylate kinase OS=Bacillus thuringiensis s... 229 1e-69
sp|Q636F5|KGUA_BACCZ Guanylate kinase OS=Bacillus cereus (strain ... 229 1e-69
sp|Q732K0|KGUA_BACC1 Guanylate kinase OS=Bacillus cereus (strain ... 229 1e-69
sp|Q81WG7|KGUA_BACAN Guanylate kinase OS=Bacillus anthracis OX=13... 229 1e-69
sp|Q82SQ3|KGUA_NITEU Guanylate kinase OS=Nitrosomonas europaea (s... 228 1e-69
sp|Q9KXS0|KGUA_STRCO Guanylate kinase OS=Streptomyces coelicolor ... 228 1e-69
sp|Q47R17|KGUA_THEFY Guanylate kinase OS=Thermobifida fusca (stra... 228 1e-69
sp|Q8UGD7|KGUA_AGRFC Guanylate kinase OS=Agrobacterium fabrum (st... 229 1e-69
sp|Q0AQC4|KGUA_MARMM Guanylate kinase OS=Maricaulis maris (strain... 229 1e-69
sp|Q110R6|KGUA_TRIEI Guanylate kinase OS=Trichodesmium erythraeum... 228 1e-69
sp|Q2RXB1|KGUA_RHORT Guanylate kinase OS=Rhodospirillum rubrum (s... 229 2e-69
sp|Q5YTM7|KGUA_NOCFA Guanylate kinase OS=Nocardia farcinica (stra... 228 2e-69
sp|Q7VDB6|KGUA_PROMA Guanylate kinase OS=Prochlorococcus marinus ... 226 4e-69
sp|Q5FJH2|KGUA_LACAC Guanylate kinase OS=Lactobacillus acidophilu... 226 7e-69
sp|Q87DG5|KGUA_XYLFT Guanylate kinase OS=Xylella fastidiosa (stra... 226 7e-69
sp|Q8GAU4|KGUA_STRKA Guanylate kinase OS=Streptomyces kasugaensis... 226 1e-68
sp|Q7V2K9|KGUA_PROMP Guanylate kinase OS=Prochlorococcus marinus ... 225 1e-68
sp|Q166A7|KGUA_ROSDO Guanylate kinase OS=Roseobacter denitrifican... 226 1e-68
sp|Q5FS85|KGUA_GLUOX Guanylate kinase OS=Gluconobacter oxydans (s... 226 1e-68
sp|Q6G053|KGUA_BARQU Guanylate kinase OS=Bartonella quintana (str... 226 2e-68
sp|P60555|KGUA_PROMM Guanylate kinase OS=Prochlorococcus marinus ... 224 3e-68
sp|Q1MJ02|KGUA_RHIJ3 Guanylate kinase OS=Rhizobium johnstonii (st... 225 3e-68
sp|Q9KX62|KGUA_MYCGA Guanylate kinase OS=Mycoplasmoides gallisept... 224 3e-68
sp|Q1QKV7|KGUA_NITHX Guanylate kinase OS=Nitrobacter hamburgensis... 225 4e-68
sp|Q819T6|KGUA_BACCR Guanylate kinase OS=Bacillus cereus (strain ... 224 4e-68
sp|Q3SRZ7|KGUA_NITWN Guanylate kinase OS=Nitrobacter winogradskyi... 224 5e-68
sp|Q9PD76|KGUA_XYLFA Guanylate kinase OS=Xylella fastidiosa (stra... 224 6e-68
sp|Q5N570|KGUA_SYNP6 Guanylate kinase OS=Synechococcus sp. (strai... 223 7e-68
sp|Q984S9|KGUA_RHILO Guanylate kinase OS=Mesorhizobium japonicum ... 224 9e-68
sp|Q9X215|KGUA_THEMA Guanylate kinase OS=Thermotoga maritima (str... 223 1e-67
sp|Q28PK5|KGUA_JANSC Guanylate kinase OS=Jannaschia sp. (strain C... 223 1e-67
sp|Q2JQB9|KGUA_SYNJA Guanylate kinase OS=Synechococcus sp. (strai... 223 2e-67
sp|Q215S7|KGUA_RHOPB Guanylate kinase OS=Rhodopseudomonas palustr... 222 4e-67
sp|Q2IL45|KGUA_ANADE Guanylate kinase OS=Anaeromyxobacter dehalog... 222 6e-67
sp|Q0BPZ9|KGUA_GRABC Guanylate kinase OS=Granulibacter bethesdens... 221 6e-67
sp|Q2J840|KGUA_FRACC Guanylate kinase OS=Frankia casuarinae (stra... 220 6e-67
sp|Q5GS56|KGUA_WOLTR Guanylate kinase OS=Wolbachia sp. subsp. Bru... 221 7e-67
sp|Q9ZMB7|KGUA_HELPJ Guanylate kinase OS=Helicobacter pylori (str... 221 7e-67
sp|Q2JQ59|KGUA_SYNJB Guanylate kinase OS=Synechococcus sp. (strai... 222 7e-67
sp|P56103|KGUA_HELPY Guanylate kinase OS=Helicobacter pylori (str... 221 8e-67
sp|Q1CUI1|KGUA_HELPH Guanylate kinase OS=Helicobacter pylori (str... 221 1e-66
sp|Q1AVZ3|KGUA_RUBXD Guanylate kinase OS=Rubrobacter xylanophilus... 220 1e-66
sp|P9WKE9|KGUA_MYCTU Guanylate kinase OS=Mycobacterium tuberculos... 221 1e-66
sp|P9WKE8|KGUA_MYCTO Guanylate kinase OS=Mycobacterium tuberculos... 221 1e-66
sp|P0A5I5|KGUA_MYCBO Guanylate kinase OS=Mycobacterium bovis (str... 221 1e-66
sp|Q73HV1|KGUA_WOLPM Guanylate kinase OS=Wolbachia pipientis wMel... 220 2e-66
sp|Q6AJ91|KGUA_DESPS Guanylate kinase OS=Desulfotalea psychrophil... 220 2e-66
sp|Q255A8|KGUA_CHLFF Guanylate kinase OS=Chlamydia felis (strain ... 219 3e-66
sp|Q1B9F6|KGUA_MYCSS Guanylate kinase OS=Mycobacterium sp. (strai... 219 3e-66
sp|Q7NK59|KGUA_GLOVI Guanylate kinase OS=Gloeobacter violaceus (s... 219 3e-66
sp|P47353|KGUA_MYCGE Guanylate kinase OS=Mycoplasma genitalium (s... 220 4e-66
sp|Q9A7N9|KGUA_CAUVC Guanylate kinase OS=Caulobacter vibrioides (... 219 4e-66
sp|Q1D3A6|KGUA_MYXXD Guanylate kinase OS=Myxococcus xanthus (stra... 219 5e-66
sp|Q0C093|KGUA_HYPNA Guanylate kinase OS=Hyphomonas neptunium (st... 219 9e-66
sp|Q6MDG3|KGUA_PARUW Guanylate kinase OS=Protochlamydia amoebophi... 218 9e-66
sp|Q2A2K6|KGUA_FRATH Guanylate kinase OS=Francisella tularensis s... 218 1e-65
sp|Q5NEY6|KGUA_FRATT Guanylate kinase OS=Francisella tularensis s... 217 1e-65
sp|Q14GD9|KGUA_FRAT1 Guanylate kinase OS=Francisella tularensis s... 217 1e-65
sp|Q31C67|KGUA_PROM9 Guanylate kinase OS=Prochlorococcus marinus ... 216 3e-65
sp|Q1IK22|KGUA_KORVE Guanylate kinase OS=Koribacter versatilis (s... 218 4e-65
sp|P75526|KGUA_MYCPN Guanylate kinase OS=Mycoplasma pneumoniae (s... 218 5e-65
sp|Q0BL54|KGUA_FRATO Guanylate kinase OS=Francisella tularensis s... 216 5e-65
sp|Q5HTT7|KGUA_CAMJR Guanylate kinase OS=Campylobacter jejuni (st... 216 7e-65
sp|Q9PNB8|KGUA_CAMJE Guanylate kinase OS=Campylobacter jejuni sub... 216 7e-65
sp|Q491W5|KGUA_BLOPB Guanylate kinase OS=Blochmannia pennsylvanic... 216 8e-65
sp|Q8Y672|KGUA_LISMO Guanylate kinase OS=Listeria monocytogenes s... 216 8e-65
sp|Q71YI9|KGUA_LISMF Guanylate kinase OS=Listeria monocytogenes s... 216 8e-65
sp|O84033|KGUA_CHLTR Guanylate kinase OS=Chlamydia trachomatis (s... 215 1e-64
sp|Q3KMZ2|KGUA_CHLTA Guanylate kinase OS=Chlamydia trachomatis se... 215 1e-64
sp|Q7VIA1|KGUA_HELHP Guanylate kinase OS=Helicobacter hepaticus (... 214 2e-64
sp|Q2GHE0|KGUA_EHRCR Guanylate kinase OS=Ehrlichia chaffeensis (s... 215 2e-64
sp|Q6F1S1|KGUA_MESFL Guanylate kinase OS=Mesoplasma florum (strai... 218 2e-64
sp|Q9PQS9|KGUA_UREPA Guanylate kinase OS=Ureaplasma parvum serova... 214 2e-64
sp|Q9CCQ7|KGUA_MYCLE Guanylate kinase OS=Mycobacterium leprae (st... 214 3e-64
sp|Q8RHI9|KGUA_FUSNN Guanylate kinase OS=Fusobacterium nucleatum ... 213 4e-64
sp|Q9RS38|KGUA_DEIRA Guanylate kinase OS=Deinococcus radiodurans ... 215 4e-64
sp|Q0S0L7|KGUA_RHOJR Guanylate kinase OS=Rhodococcus jostii (stra... 213 6e-64
sp|Q822M8|KGUA_CHLCV Guanylate kinase OS=Chlamydia caviae (strain... 212 2e-63
sp|Q9PL09|KGUA_CHLMU Guanylate kinase OS=Chlamydia muridarum (str... 212 2e-63
sp|Q8G813|KGUA_BIFLO Guanylate kinase OS=Bifidobacterium longum (... 211 2e-63
sp|Q2GD44|KGUA_NEOSM Guanylate kinase OS=Neorickettsia sennetsu (... 212 2e-63
sp|Q7UP92|KGUA_RHOBA Guanylate kinase OS=Rhodopirellula baltica (... 212 2e-63
sp|Q9Z961|KGUA_CHLPN Guanylate kinase OS=Chlamydia pneumoniae OX=... 211 3e-63
sp|Q2G9M5|KGUA_NOVAD Guanylate kinase OS=Novosphingobium aromatic... 212 3e-63
sp|Q2GLF7|KGUA_ANAPZ Guanylate kinase OS=Anaplasma phagocytophilu... 212 3e-63
sp|P60550|KGUA_CORDI Guanylate kinase OS=Corynebacterium diphther... 211 3e-63
sp|Q6AF82|KGUA_LEIXX Guanylate kinase OS=Leifsonia xyli subsp. xy... 213 3e-63
sp|Q1IW06|KGUA_DEIGD Guanylate kinase OS=Deinococcus geothermalis... 212 8e-63
sp|Q3YRE2|KGUA_EHRCJ Guanylate kinase OS=Ehrlichia canis (strain ... 210 1e-62
sp|Q3B204|KGUA_CHLL3 Guanylate kinase OS=Chlorobium luteolum (str... 209 1e-62
sp|P60553|KGUA_MYCPA Guanylate kinase OS=Mycolicibacterium paratu... 210 1e-62
sp|Q6A8H6|KGUA_CUTAK Guanylate kinase OS=Cutibacterium acnes (str... 209 1e-62
sp|Q3AQL3|KGUA_CHLCH Guanylate kinase OS=Chlorobium chlorochromat... 208 3e-62
sp|Q8NQ42|KGUA_CORGL Guanylate kinase OS=Corynebacterium glutamic... 208 3e-62
sp|Q5L5M1|KGUA_CHLAB Guanylate kinase OS=Chlamydia abortus (strai... 208 5e-62
sp|Q8KPQ7|KGUA_SYNE7 Guanylate kinase OS=Synechococcus elongatus ... 207 6e-62
sp|Q8A677|KGUA_BACTN Guanylate kinase OS=Bacteroides thetaiotaomi... 208 7e-62
sp|Q8FT45|KGUA_COREF Guanylate kinase OS=Corynebacterium efficien... 206 2e-61
sp|Q7MWS7|KGUA_PORGI Guanylate kinase OS=Porphyromonas gingivalis... 206 2e-61
sp|Q30PL1|KGUA_SULDN Guanylate kinase OS=Sulfurimonas denitrifica... 206 3e-61
sp|Q4FMR1|KGUA_PELUB Guanylate kinase OS=Pelagibacter ubique (str... 206 4e-61
sp|Q46GV6|KGUA_PROMT Guanylate kinase OS=Prochlorococcus marinus ... 205 4e-61
sp|Q8KFS5|KGUA_CHLTE Guanylate kinase OS=Chlorobaculum tepidum (s... 205 6e-61
sp|Q6MU25|KGUA_MYCMS Guanylate kinase OS=Mycoplasma mycoides subs... 207 2e-60
sp|Q3ZWD8|KGUA_DEHMC Guanylate kinase OS=Dehalococcoides mccartyi... 204 2e-60
sp|Q2SSR8|KGUA_MYCCT Guanylate kinase OS=Mycoplasma capricolum su... 207 3e-60
sp|Q5HAK7|KGUA_EHRRW Guanylate kinase OS=Ehrlichia ruminantium (s... 203 3e-60
sp|Q5FFZ9|KGUA_EHRRG Guanylate kinase OS=Ehrlichia ruminantium (s... 203 3e-60
sp|Q2LQ62|KGUA_SYNAS Guanylate kinase OS=Syntrophus aciditrophicu... 199 1e-58
sp|P60549|KGUA_BDEBA Guanylate kinase OS=Bdellovibrio bacteriovor... 197 5e-58
sp|Q98PN5|KGUA_MYCPU Guanylate kinase OS=Mycoplasmopsis pulmonis ... 197 6e-58
sp|Q83GE3|KGUA_TROWT Guanylate kinase OS=Tropheryma whipplei (str... 195 2e-57
sp|Q83HT8|KGUA_TROW8 Guanylate kinase OS=Tropheryma whipplei (str... 195 2e-57
sp|Q3ZAF9|KGUA_DEHM1 Guanylate kinase OS=Dehalococcoides mccartyi... 194 1e-56
sp|Q4AAI1|KGUA_MESHJ Guanylate kinase OS=Mesomycoplasma hyopneumo... 191 1e-55
sp|Q601H3|KGUA_MESH2 Guanylate kinase OS=Mesomycoplasma hyopneumo... 191 1e-55
sp|Q4A8L2|KGUA_MESH7 Guanylate kinase OS=Mesomycoplasma hyopneumo... 191 2e-55
sp|Q11XI0|KGUA_CYTH3 Guanylate kinase OS=Cytophaga hutchinsonii (... 190 2e-55
sp|Q2S6J5|KGUA_SALRD Guanylate kinase OS=Salinibacter ruber (stra... 189 4e-55
sp|Q8EVJ9|KGUA_MALP2 Guanylate kinase OS=Malacoplasma penetrans (... 187 2e-54
sp|Q4JVH4|KGUA_CORJK Guanylate kinase OS=Corynebacterium jeikeium... 187 3e-54
sp|Q4A6S7|KGUA_MYCS5 Guanylate kinase OS=Mycoplasmopsis synoviae ... 186 8e-54
sp|Q7MAK5|KGUA_WOLSU Guanylate kinase OS=Wolinella succinogenes (... 186 9e-54
sp|Q10M74|GMK2_ORYSJ Guanylate kinase 2, chloroplastic/mitochondr... 185 2e-52
sp|Q8D2E8|KGUA_WIGBR Guanylate kinase OS=Wigglesworthia glossinid... 181 9e-52
sp|P0C0M8|KGUA_STAEP Guanylate kinase (Fragment) OS=Staphylococcu... 177 2e-51
sp|Q64PY1|KGUA_BACFR Guanylate kinase OS=Bacteroides fragilis (st... 180 2e-51
sp|Q5L9N9|KGUA_BACFN Guanylate kinase OS=Bacteroides fragilis (st... 180 2e-51
sp|Q94JM2|GMK3_ARATH Guanylate kinase 3, chloroplastic OS=Arabido... 177 1e-49
sp|Q6KH87|KGUA_MESM1 Guanylate kinase OS=Mesomycoplasma mobile (s... 167 1e-46
sp|Q9D5S7|LRGUK_MOUSE Leucine-rich repeat and guanylate kinase do... 174 2e-44
sp|Q96M69|LRGUK_HUMAN Leucine-rich repeat and guanylate kinase do... 173 3e-44
sp|Q01230|A57_VACCW Guanylate kinase homolog OS=Vaccinia virus (s... 143 1e-38
sp|P21074|A57_VACCC Guanylate kinase homolog OS=Vaccinia virus (s... 140 7e-38
sp|Q9Z101|PAR6A_MOUSE Partitioning defective 6 homolog alpha OS=M... 96.3 3e-20
sp|Q6B4M5|PAR6A_RAT Partitioning defective 6 homolog alpha OS=Rat... 95.9 4e-20
sp|Q9NPB6|PAR6A_HUMAN Partitioning defective 6 homolog alpha OS=H... 94.0 2e-19
sp|Q9NAN2|PAR6_CAEEL Partitioning defective protein 6 OS=Caenorha... 92.4 4e-19
sp|Q9BYG5|PAR6B_HUMAN Partitioning defective 6 homolog beta OS=Ho... 93.2 4e-19
sp|Q9JK84|PAR6G_MOUSE Partitioning defective 6 homolog gamma OS=M... 93.2 4e-19
sp|Q9BYG4|PAR6G_HUMAN Partitioning defective 6 homolog gamma OS=H... 92.8 6e-19
sp|Q9C0E4|GRIP2_HUMAN Glutamate receptor-interacting protein 2 OS... 94.4 2e-18
sp|Q9JK83|PAR6B_MOUSE Partitioning defective 6 homolog beta OS=Mu... 91.3 2e-18
sp|Q9WTW1|GRIP2_RAT Glutamate receptor-interacting protein 2 OS=R... 92.0 7e-18
sp|O88951|LIN7B_MOUSE Protein lin-7 homolog B OS=Mus musculus OX=... 85.9 8e-18
sp|Q9Z252|LIN7B_RAT Protein lin-7 homolog B OS=Rattus norvegicus ... 85.9 9e-18
sp|Q2KIB6|LIN7B_BOVIN Protein lin-7 homolog B OS=Bos taurus OX=99... 85.5 9e-18
sp|Q9HAP6|LIN7B_HUMAN Protein lin-7 homolog B OS=Homo sapiens OX=... 85.5 1e-17
sp|A8E0R9|GRIP2_XENLA Glutamate receptor-interacting protein 2 OS... 89.7 4e-17
sp|Q0U6X7|HSE1_PHANO Class E vacuolar protein-sorting machinery p... 89.0 5e-17
sp|Q5F425|LIN7C_CHICK Protein lin-7 homolog C OS=Gallus gallus OX... 82.8 8e-17
sp|Q792I0|LIN7C_RAT Protein lin-7 homolog C OS=Rattus norvegicus ... 82.8 9e-17
sp|Q5RAA5|LIN7C_PONAB Protein lin-7 homolog C OS=Pongo abelii OX=... 82.8 9e-17
sp|O88952|LIN7C_MOUSE Protein lin-7 homolog C OS=Mus musculus OX=... 82.8 9e-17
sp|Q9NUP9|LIN7C_HUMAN Protein lin-7 homolog C OS=Homo sapiens OX=... 82.8 9e-17
sp|Q0P5F3|LIN7C_BOVIN Protein lin-7 homolog C OS=Bos taurus OX=99... 82.8 9e-17
sp|A1A5G4|MAGI3_XENTR Membrane-associated guanylate kinase, WW an... 83.2 5e-15
sp|Q9Y3R0|GRIP1_HUMAN Glutamate receptor-interacting protein 1 OS... 82.8 6e-15
sp|Q9JK71|MAGI3_RAT Membrane-associated guanylate kinase, WW and ... 82.4 8e-15
sp|Q9EQJ9|MAGI3_MOUSE Membrane-associated guanylate kinase, WW an... 82.0 1e-14
sp|P97879|GRIP1_RAT Glutamate receptor-interacting protein 1 OS=R... 81.6 1e-14
sp|Q5TCQ9|MAGI3_HUMAN Membrane-associated guanylate kinase, WW an... 81.6 1e-14
sp|Q5F488|MAGI3_CHICK Membrane-associated guanylate kinase, WW an... 80.9 2e-14
sp|Q925T6|GRIP1_MOUSE Glutamate receptor-interacting protein 1 OS... 80.1 4e-14
sp|Q60631|GRB2_MOUSE Growth factor receptor-bound protein 2 OS=Mu... 73.2 2e-13
sp|P62994|GRB2_RAT Growth factor receptor-bound protein 2 OS=Ratt... 73.2 2e-13
sp|Q5R4J7|GRB2_PONAB Growth factor receptor-bound protein 2 OS=Po... 73.2 2e-13
sp|P62993|GRB2_HUMAN Growth factor receptor-bound protein 2 OS=Ho... 73.2 2e-13
sp|Q4L1J4|MAGI1_RAT Membrane-associated guanylate kinase, WW and ... 77.4 3e-13
sp|Q96QZ7|MAGI1_HUMAN Membrane-associated guanylate kinase, WW an... 76.2 6e-13
sp|Q6RHR9|MAGI1_MOUSE Membrane-associated guanylate kinase, WW an... 76.2 6e-13
sp|Q80U72|SCRIB_MOUSE Protein scribble homolog OS=Mus musculus OX... 73.9 3e-12
sp|Q8TEW0|PARD3_HUMAN Partitioning defective 3 homolog OS=Homo sa... 70.1 5e-11
sp|Q9Z340|PARD3_RAT Partitioning defective 3 homolog OS=Rattus no... 68.5 2e-10
sp|Q99NH2|PARD3_MOUSE Partitioning defective 3 homolog OS=Mus mus... 68.2 2e-10
sp|Q9ES64|USH1C_MOUSE Harmonin OS=Mus musculus OX=10090 GN=Ush1c ... 67.8 2e-10
sp|Q9Y6V0|PCLO_HUMAN Protein piccolo OS=Homo sapiens OX=9606 GN=P... 67.8 3e-10
sp|Q3MHQ0|USH1C_BOVIN Harmonin OS=Bos taurus OX=9913 GN=USH1C PE=... 65.8 6e-10
Sequences not found previously or not previously below threshold:
sp|Q9Z250|LIN7A_RAT Protein lin-7 homolog A OS=Rattus norvegicus ... 89.3 1e-18
sp|Q8JZS0|LIN7A_MOUSE Protein lin-7 homolog A OS=Mus musculus OX=... 89.3 1e-18
sp|O14910|LIN7A_HUMAN Protein lin-7 homolog A OS=Homo sapiens OX=... 89.3 1e-18
sp|Q32LM6|LIN7A_BOVIN Protein lin-7 homolog A OS=Bos taurus OX=99... 89.3 1e-18
sp|Q16A32|RBKTP_ROSDO Bifunctional ribose 1,5-bisphosphokinase-th... 90.5 1e-17
sp|B3PXI8|PHNN_RHIE6 Ribose 1,5-bisphosphate phosphokinase PhnN O... 83.6 5e-17
sp|E1SHE4|PHNN_PANVC Ribose 1,5-bisphosphate phosphokinase PhnN O... 81.3 2e-16
sp|Q3SGK8|PHNN_THIDA Ribose 1,5-bisphosphate phosphokinase PhnN O... 81.3 2e-16
sp|Q9BXL6|CAR14_HUMAN Caspase recruitment domain-containing prote... 86.3 4e-16
sp|Q1GL02|PHNN_RUEST Ribose 1,5-bisphosphate phosphokinase PhnN O... 79.7 7e-16
sp|A6V255|PHNN_PSEA7 Ribose 1,5-bisphosphate phosphokinase PhnN O... 79.7 7e-16
sp|Q89V30|PHNN_BRADU Ribose 1,5-bisphosphate phosphokinase PhnN O... 79.7 9e-16
sp|D0KG93|PHNN_PECPW Ribose 1,5-bisphosphate phosphokinase PhnN O... 77.0 6e-15
sp|Q99KF0|CAR14_MOUSE Caspase recruitment domain-containing prote... 80.9 2e-14
sp|Q8X5P4|PHNN_ECO57 Ribose 1,5-bisphosphate phosphokinase PhnN O... 75.5 2e-14
sp|P16690|PHNN_ECOLI Ribose 1,5-bisphosphate phosphokinase PhnN O... 75.1 3e-14
sp|Q329H3|PHNN_SHIDS Ribose 1,5-bisphosphate phosphokinase PhnN O... 74.3 4e-14
sp|A9CKM5|PHNN_AGRFC Ribose 1,5-bisphosphate phosphokinase PhnN O... 73.9 6e-14
sp|B1LPR3|PHNN_ECOSM Ribose 1,5-bisphosphate phosphokinase PhnN O... 73.6 1e-13
sp|Q6D9W6|PHNN_PECAS Ribose 1,5-bisphosphate phosphokinase PhnN O... 73.2 1e-13
sp|C1DLT0|PHNN_AZOVD Ribose 1,5-bisphosphate phosphokinase PhnN O... 73.2 1e-13
sp|Q9WVQ1|MAGI2_MOUSE Membrane-associated guanylate kinase, WW an... 77.8 2e-13
sp|Q9MZL7|CACB1_BOVIN Voltage-dependent L-type calcium channel su... 77.4 2e-13
sp|O88382|MAGI2_RAT Membrane-associated guanylate kinase, WW and ... 77.8 2e-13
sp|Q02641|CACB1_HUMAN Voltage-dependent L-type calcium channel su... 77.0 2e-13
sp|Q61235|SNTB2_MOUSE Beta-2-syntrophin OS=Mus musculus OX=10090 ... 76.2 3e-13
sp|Q13425|SNTB2_HUMAN Beta-2-syntrophin OS=Homo sapiens OX=9606 G... 76.2 3e-13
sp|Q8R3Z5|CACB1_MOUSE Voltage-dependent L-type calcium channel su... 76.6 3e-13
sp|Q12923|PTN13_HUMAN Tyrosine-protein phosphatase non-receptor t... 77.4 4e-13
sp|Q99L88|SNTB1_MOUSE Beta-1-syntrophin OS=Mus musculus OX=10090 ... 76.2 4e-13
sp|D2C357|PHNN_DICZ5 Ribose 1,5-bisphosphate phosphokinase PhnN O... 71.6 4e-13
sp|P54283|CACB1_RAT Voltage-dependent L-type calcium channel subu... 76.2 4e-13
sp|A5G2M7|PHNN_ACICJ Ribose 1,5-bisphosphate phosphokinase PhnN O... 71.2 5e-13
sp|Q86UL8|MAGI2_HUMAN Membrane-associated guanylate kinase, WW an... 76.6 5e-13
sp|Q4WHP5|HSE1_ASPFU Class E vacuolar protein-sorting machinery p... 75.9 6e-13
sp|A1DFN5|HSE1_NEOFI Class E vacuolar protein-sorting machinery p... 75.5 6e-13
sp|Q9MZL3|CACB3_BOVIN Voltage-dependent L-type calcium channel su... 75.1 7e-13
sp|Q9NY99|SNTG2_HUMAN Gamma-2-syntrophin OS=Homo sapiens OX=9606 ... 75.1 8e-13
sp|Q9HD26|GOPC_HUMAN Golgi-associated PDZ and coiled-coil motif-c... 74.7 8e-13
sp|Q13884|SNTB1_HUMAN Beta-1-syntrophin OS=Homo sapiens OX=9606 G... 75.1 9e-13
sp|O55164|MPDZ_RAT Multiple PDZ domain protein OS=Rattus norvegic... 75.9 9e-13
sp|Q66II3|GRB2_XENTR Growth factor receptor-bound protein 2 OS=Xe... 71.6 1e-12
sp|P54285|CACB3_MOUSE Voltage-dependent L-type calcium channel su... 74.3 1e-12
sp|Q6NBY8|PHNN_RHOPA Ribose 1,5-bisphosphate phosphokinase PhnN O... 70.9 1e-12
sp|P54286|CACB3_RABIT Voltage-dependent L-type calcium channel su... 74.3 1e-12
sp|Q8BH60|GOPC_MOUSE Golgi-associated PDZ and coiled-coil motif-c... 74.3 1e-12
sp|Q4H4B6|SCRIB_DANRE Protein scribble homolog OS=Danio rerio OX=... 75.5 1e-12
sp|P54287|CACB3_RAT Voltage-dependent L-type calcium channel subu... 74.3 1e-12
sp|E3G1M3|PHNN_ENTLS Ribose 1,5-bisphosphate phosphokinase PhnN O... 70.1 1e-12
sp|O75970|MPDZ_HUMAN Multiple PDZ domain protein OS=Homo sapiens ... 75.1 1e-12
sp|Q925E0|SNTG2_MOUSE Gamma-2-syntrophin OS=Mus musculus OX=10090... 74.3 1e-12
sp|A9MGI9|PHNN_SALAR Ribose 1,5-bisphosphate phosphokinase PhnN O... 70.1 2e-12
sp|P54284|CACB3_HUMAN Voltage-dependent L-type calcium channel su... 73.9 2e-12
sp|Q6GPJ9|GRB2B_XENLA Growth factor receptor-bound protein 2-B OS... 70.9 2e-12
sp|Q0CJU8|HSE1_ASPTN Class E vacuolar protein-sorting machinery p... 73.9 2e-12
sp|Q07883|GRB2_CHICK Growth factor receptor-bound protein 2 OS=Ga... 70.5 2e-12
sp|A2QW93|HSE1_ASPNC Class E vacuolar protein-sorting machinery p... 73.9 2e-12
sp|F1MAD2|INADL_RAT InaD-like protein OS=Rattus norvegicus OX=101... 74.3 2e-12
sp|A1CEK6|HSE1_ASPCL Class E vacuolar protein-sorting machinery p... 73.6 2e-12
sp|Q61234|SNTA1_MOUSE Alpha-1-syntrophin OS=Mus musculus OX=10090... 73.2 3e-12
sp|Q1E878|HSE1_COCIM Class E vacuolar protein-sorting machinery p... 73.6 3e-12
sp|Q63ZW7|INADL_MOUSE InaD-like protein OS=Mus musculus OX=10090 ... 73.9 4e-12
sp|Q8VBX6|MPDZ_MOUSE Multiple PDZ domain protein OS=Mus musculus ... 73.6 4e-12
sp|Q0P5E6|SNTA1_BOVIN Alpha-1-syntrophin OS=Bos taurus OX=9913 GN... 72.4 5e-12
sp|Q28626|SNTA1_RABIT Alpha-1-syntrophin OS=Oryctolagus cuniculus... 72.4 5e-12
sp|Q5BBL4|HSE1_EMENI Class E vacuolar protein-sorting machinery p... 72.4 5e-12
sp|Q7CKG8|PHNN_YERPE Ribose 1,5-bisphosphate phosphokinase PhnN O... 68.5 6e-12
sp|P87379|GRB2A_XENLA Growth factor receptor-bound protein 2-A OS... 69.3 6e-12
sp|Q13424|SNTA1_HUMAN Alpha-1-syntrophin OS=Homo sapiens OX=9606 ... 71.6 9e-12
sp|Q8NI35|INADL_HUMAN InaD-like protein OS=Homo sapiens OX=9606 G... 72.4 1e-11
sp|B2AIF3|RBKTP_CUPTR Bifunctional ribose 1,5-bisphosphokinase-th... 71.6 1e-11
sp|Q64512|PTN13_MOUSE Tyrosine-protein phosphatase non-receptor t... 72.4 1e-11
sp|Q5RD32|GOPC_PONAB Golgi-associated PDZ and coiled-coil motif-c... 70.9 1e-11
sp|Q9WVJ4|SYJ2B_RAT Synaptojanin-2-binding protein OS=Rattus norv... 66.2 1e-11
sp|Q3T0C9|SYJ2B_BOVIN Synaptojanin-2-binding protein OS=Bos tauru... 65.8 2e-11
sp|Q14160|SCRIB_HUMAN Protein scribble homolog OS=Homo sapiens OX... 71.6 2e-11
sp|E2QYC9|INADL_CANLF InaD-like protein OS=Canis lupus familiaris... 71.6 2e-11
sp|A8IA58|RBKTP_AZOC5 Bifunctional ribose 1,5-bisphosphokinase-th... 71.2 2e-11
sp|Q46UT0|RBKTP_CUPPJ Bifunctional ribose 1,5-bisphosphokinase-th... 70.9 2e-11
sp|Q9D6K5|SYJ2B_MOUSE Synaptojanin-2-binding protein OS=Mus muscu... 65.8 2e-11
sp|Q5ZIK2|PDZ11_CHICK PDZ domain-containing protein 11 OS=Gallus ... 65.5 2e-11
sp|A6TH13|PHNN_KLEP7 Ribose 1,5-bisphosphate phosphokinase PhnN O... 67.0 2e-11
sp|P57105|SYJ2B_HUMAN Synaptojanin-2-binding protein OS=Homo sapi... 65.5 3e-11
sp|Q7NWY0|PHNN_CHRVO Ribose 1,5-bisphosphate phosphokinase PhnN O... 66.6 3e-11
sp|Q6XJU9|OSTF1_MONAL Osteoclast-stimulating factor 1 OS=Monopter... 67.0 3e-11
sp|C7LNQ3|PHNN_DESBD Ribose 1,5-bisphosphate phosphokinase PhnN O... 65.5 6e-11
sp|D4A055|CACB4_RAT Voltage-dependent L-type calcium channel subu... 68.9 6e-11
sp|Q8R0S4|CACB4_MOUSE Voltage-dependent L-type calcium channel su... 68.9 6e-11
sp|O00305|CACB4_HUMAN Voltage-dependent L-type calcium channel su... 68.9 7e-11
sp|Q24008|INAD_DROME Inactivation-no-after-potential D protein OS... 68.9 7e-11
sp|A4RF61|HSE1_PYRO7 Class E vacuolar protein-sorting machinery p... 68.9 8e-11
sp|Q6TGW5|OSTF1_DANRE Osteoclast-stimulating factor 1 OS=Danio re... 65.8 8e-11
sp|C3K5M3|PHNN_PSEFS Ribose 1,5-bisphosphate phosphokinase PhnN O... 64.7 1e-10
sp|Q0K3R9|RBKTP_CUPNH Bifunctional ribose 1,5-bisphosphokinase-th... 68.2 1e-10
sp|Q93646|SNT1_CAEEL Syntrophin-1 OS=Caenorhabditis elegans OX=62... 67.8 1e-10
sp|E7FDW2|PZR3B_DANRE E3 ubiquitin-protein ligase PDZRN3-B OS=Dan... 68.5 1e-10
sp|A6SU94|PHNN_JANMA Ribose 1,5-bisphosphate phosphokinase PhnN O... 67.4 2e-10
sp|Q9CZG9|PDZ11_MOUSE PDZ domain-containing protein 11 OS=Mus mus... 62.8 2e-10
sp|Q6QA76|PDZ11_PIG PDZ domain-containing protein 11 OS=Sus scrof... 62.8 2e-10
sp|Q32LE7|PDZ11_BOVIN PDZ domain-containing protein 11 OS=Bos tau... 62.8 2e-10
sp|Q9NB04|PATJ_DROME Patj homolog OS=Drosophila melanogaster OX=7... 67.8 2e-10
sp|Q62662|FRK_RAT Tyrosine-protein kinase FRK OS=Rattus norvegicu... 67.0 2e-10
sp|Q7S6J4|HSE1_NEUCR Class E vacuolar protein-sorting machinery p... 67.4 3e-10
sp|Q57D38|PHNN_BRUAB Ribose 1,5-bisphosphate phosphokinase PhnN O... 63.2 4e-10
sp|C0RJ73|PHNN_BRUMB Ribose 1,5-bisphosphate phosphokinase PhnN O... 62.8 5e-10
sp|Q7KRY7|SCRIB_DROME Protein lap4 OS=Drosophila melanogaster OX=... 66.6 6e-10
sp|Q922K9|FRK_MOUSE Tyrosine-protein kinase FRK OS=Mus musculus O... 65.8 7e-10
sp|Q9CSB4|PAR3L_MOUSE Partitioning defective 3 homolog B OS=Mus m... 65.8 9e-10
sp|Q925E1|SNTG1_MOUSE Gamma-1-syntrophin OS=Mus musculus OX=10090... 65.1 1e-09
sp|A5PKA5|SNX27_BOVIN Sorting nexin-27 OS=Bos taurus OX=9913 GN=S... 65.1 1e-09
sp|Q8K4V4|SNX27_RAT Sorting nexin-27 OS=Rattus norvegicus OX=1011... 65.1 1e-09
sp|Q9Y6N9|USH1C_HUMAN Harmonin OS=Homo sapiens OX=9606 GN=USH1C P... 65.1 1e-09
sp|Q3UHD6|SNX27_MOUSE Sorting nexin-27 OS=Mus musculus OX=10090 G... 65.1 1e-09
sp|A1T0U7|PHNN_PSYIN Ribose 1,5-bisphosphate phosphokinase PhnN O... 62.0 1e-09
sp|Q9NSN8|SNTG1_HUMAN Gamma-1-syntrophin OS=Homo sapiens OX=9606 ... 65.1 1e-09
sp|Q9PU36|PCLO_CHICK Protein piccolo (Fragment) OS=Gallus gallus ... 65.5 1e-09
sp|Q9UPQ7|PZRN3_HUMAN E3 ubiquitin-protein ligase PDZRN3 OS=Homo ... 65.1 1e-09
sp|Q5EBL8|PDZ11_HUMAN PDZ domain-containing protein 11 OS=Homo sa... 60.1 2e-09
sp|Q9P202|WHRN_HUMAN Whirlin OS=Homo sapiens OX=9606 GN=WHRN PE=1... 65.1 2e-09
sp|Q8TEW8|PAR3L_HUMAN Partitioning defective 3 homolog B OS=Homo ... 65.1 2e-09
sp|Q9QYX7|PCLO_MOUSE Protein piccolo OS=Mus musculus OX=10090 GN=... 65.1 2e-09
sp|Q6NXB2|PDZ11_DANRE PDZ domain-containing protein 11 OS=Danio r... 59.7 2e-09
sp|Q9BXL7|CAR11_HUMAN Caspase recruitment domain-containing prote... 64.7 3e-09
sp|Q6ZMN7|PZRN4_HUMAN PDZ domain-containing RING finger protein 4... 64.3 3e-09
sp|P54288|CACB2_RABIT Voltage-dependent L-type calcium channel su... 63.9 3e-09
sp|Q91XL2|LNX2_MOUSE Ligand of Numb protein X 2 OS=Mus musculus O... 63.9 3e-09
sp|O35430|APBA1_RAT Amyloid-beta A4 precursor protein-binding fam... 63.9 4e-09
sp|Q8TBB1|LNX1_HUMAN E3 ubiquitin-protein ligase LNX OS=Homo sapi... 63.5 4e-09
sp|Q69ZS0|PZRN3_MOUSE E3 ubiquitin-protein ligase PDZRN3 OS=Mus m... 63.9 4e-09
sp|Q80VW5|WHRN_MOUSE Whirlin OS=Mus musculus OX=10090 GN=Whrn PE=... 63.5 4e-09
sp|P29074|PTN4_HUMAN Tyrosine-protein phosphatase non-receptor ty... 63.5 5e-09
sp|Q9MZL5|CACB2_BOVIN Voltage-dependent L-type calcium channel su... 63.2 5e-09
sp|O70263|LNX1_MOUSE E3 ubiquitin-protein ligase LNX OS=Mus muscu... 63.2 6e-09
sp|P68907|PZRN3_RAT E3 ubiquitin-protein ligase PDZRN3 OS=Rattus ... 63.2 6e-09
sp|Q08289|CACB2_HUMAN Voltage-dependent L-type calcium channel su... 62.8 7e-09
sp|O19132|NOS1_RABIT Nitric oxide synthase 1 OS=Oryctolagus cunic... 63.2 7e-09
sp|Q8MJ50|OSTF1_BOVIN Osteoclast-stimulating factor 1 OS=Bos taur... 59.7 8e-09
sp|O15018|PDZD2_HUMAN PDZ domain-containing protein 2 OS=Homo sap... 63.2 9e-09
sp|Q810W9|WHRN_RAT Whirlin OS=Rattus norvegicus OX=10116 GN=Whrn ... 62.8 9e-09
sp|Q7ZYG4|OSTF1_XENLA Osteoclast-stimulating factor 1 OS=Xenopus ... 59.7 9e-09
sp|B2RUJ5|APBA1_MOUSE Amyloid-beta A4 precursor protein-binding f... 62.4 9e-09
sp|Q02410|APBA1_HUMAN Amyloid-beta A4 precursor protein-binding f... 62.4 1e-08
sp|Q8N448|LNX2_HUMAN Ligand of Numb protein X 2 OS=Homo sapiens O... 62.4 1e-08
sp|Q9QZR8|PDZD2_RAT PDZ domain-containing protein 2 OS=Rattus nor... 62.8 1e-08
sp|Q63R14|PHNN_BURPS Ribose 1,5-bisphosphate phosphokinase PhnN O... 58.9 1e-08
sp|A1V0B1|PHNN_BURMS Ribose 1,5-bisphosphate phosphokinase PhnN O... 58.9 1e-08
sp|Q96L92|SNX27_HUMAN Sorting nexin-27 OS=Homo sapiens OX=9606 GN... 62.0 1e-08
sp|P29355|SEM5_CAEEL Sex muscle abnormal protein 5 OS=Caenorhabdi... 59.7 1e-08
sp|P42685|FRK_HUMAN Tyrosine-protein kinase FRK OS=Homo sapiens O... 61.6 1e-08
sp|Q9WU22|PTN4_MOUSE Tyrosine-protein phosphatase non-receptor ty... 62.0 1e-08
sp|Q5ZJJ9|OSTF1_CHICK Osteoclast-stimulating factor 1 OS=Gallus g... 58.9 1e-08
sp|P19517|CACB1_RABIT Voltage-dependent L-type calcium channel su... 61.6 1e-08
sp|O35867|NEB1_RAT Neurabin-1 OS=Rattus norvegicus OX=10116 GN=Pp... 61.6 2e-08
sp|Q8MJ49|OSTF1_PIG Osteoclast-stimulating factor 1 OS=Sus scrofa... 58.9 2e-08
sp|Q92882|OSTF1_HUMAN Osteoclast-stimulating factor 1 OS=Homo sap... 58.9 2e-08
sp|Q29498|NOS1_SHEEP Nitric oxide synthase 1 OS=Ovis aries OX=994... 61.6 2e-08
sp|A4D2P6|GRD2I_HUMAN Delphilin OS=Homo sapiens OX=9606 GN=GRID2I... 61.6 2e-08
sp|Q9JKS6|PCLO_RAT Protein piccolo OS=Rattus norvegicus OX=10116 ... 61.6 2e-08
sp|Q6ZM86|GRD2I_DANRE Delphilin OS=Danio rerio OX=7955 GN=grid2ip... 61.2 3e-08
sp|Q68DX3|FRPD2_HUMAN FERM and PDZ domain-containing protein 2 OS... 61.2 3e-08
sp|Q920G2|NHRF2_RAT Na(+)/H(+) exchange regulatory cofactor NHE-R... 59.7 3e-08
sp|O14907|TX1B3_HUMAN Tax1-binding protein 3 OS=Homo sapiens OX=9... 55.8 3e-08
sp|Q6P686|OSTF1_RAT Osteoclast-stimulating factor 1 OS=Rattus nor... 58.1 3e-08
sp|Q62422|OSTF1_MOUSE Osteoclast-stimulating factor 1 OS=Mus musc... 58.1 3e-08
sp|Q9DBG9|TX1B3_MOUSE Tax1-binding protein 3 OS=Mus musculus OX=1... 55.8 3e-08
sp|Q9ULJ8|NEB1_HUMAN Neurabin-1 OS=Homo sapiens OX=9606 GN=PPP1R9... 60.8 4e-08
sp|P29475|NOS1_HUMAN Nitric oxide synthase 1 OS=Homo sapiens OX=9... 60.5 5e-08
sp|Q9JHL1|NHRF2_MOUSE Na(+)/H(+) exchange regulatory cofactor NHE... 59.3 5e-08
sp|Q9P227|RHG23_HUMAN Rho GTPase-activating protein 23 OS=Homo sa... 60.5 5e-08
sp|Q8CC27|CACB2_MOUSE Voltage-dependent L-type calcium channel su... 60.1 5e-08
sp|Q69ZH9|RHG23_MOUSE Rho GTPase-activating protein 23 OS=Mus mus... 60.5 5e-08
sp|Q8VGC3|CACB2_RAT Voltage-dependent L-type calcium channel subu... 59.7 7e-08
sp|O62678|IL16_AOTTR Pro-interleukin-16 OS=Aotus trivirgatus OX=9... 59.7 7e-08
sp|Q5ZM14|NHRF1_CHICK Na(+)/H(+) exchange regulatory cofactor NHE... 58.5 7e-08
sp|Q04929|CRK_CHICK Adapter molecule crk OS=Gallus gallus OX=9031... 58.1 8e-08
sp|Q8SQG9|NHRF2_RABIT Na(+)/H(+) exchange regulatory cofactor NHE... 58.1 8e-08
sp|Q15599|NHRF2_HUMAN Na(+)/H(+) exchange regulatory cofactor NHE... 58.5 8e-08
sp|O08992|SDCB1_MOUSE Syntenin-1 OS=Mus musculus OX=10090 GN=Sdcb... 57.8 1e-07
sp|F1MCA7|LRRC7_BOVIN Leucine-rich repeat-containing protein 7 OS... 59.3 1e-07
sp|O00560|SDCB1_HUMAN Syntenin-1 OS=Homo sapiens OX=9606 GN=SDCBP... 57.8 1e-07
sp|Q96NW7|LRRC7_HUMAN Leucine-rich repeat-containing protein 7 OS... 59.3 1e-07
sp|P70587|LRRC7_RAT Leucine-rich repeat-containing protein 7 OS=R... 59.3 1e-07
sp|Q80TE7|LRRC7_MOUSE Leucine-rich repeat-containing protein 7 OS... 59.3 1e-07
sp|Q6AYQ0|MAGIX_RAT PDZ domain-containing protein MAGIX OS=Rattus... 57.8 1e-07
sp|P51140|DSH_DROME Segment polarity protein dishevelled OS=Droso... 58.5 1e-07
sp|Q8CIS0|CAR11_MOUSE Caspase recruitment domain-containing prote... 58.9 1e-07
sp|O35889|AFAD_RAT Afadin OS=Rattus norvegicus OX=10116 GN=Afdn P... 58.9 1e-07
sp|Q9V9S7|SYDE_DROME Rho GTPase-activating protein 100F OS=Drosop... 58.9 2e-07
sp|E3J0E1|PHNN_PSEI1 Ribose 1,5-bisphosphate phosphokinase PhnN O... 55.4 2e-07
sp|P27447|YES_XIPHE Tyrosine-protein kinase Yes OS=Xiphophorus he... 58.1 2e-07
sp|P46108|CRK_HUMAN Adapter molecule crk OS=Homo sapiens OX=9606 ... 57.0 2e-07
sp|Q63768|CRK_RAT Adapter molecule crk OS=Rattus norvegicus OX=10... 57.0 2e-07
sp|Q9QZQ1|AFAD_MOUSE Afadin OS=Mus musculus OX=10090 GN=Afdn PE=1... 58.5 2e-07
sp|P05433|GAGC_AVISC P47(GAG-CRK) protein OS=Avian sarcoma virus ... 57.8 2e-07
sp|E9Q9W7|PDZD7_MOUSE PDZ domain-containing protein 7 OS=Mus musc... 58.1 2e-07
sp|Q3T0X8|NHRF3_BOVIN Na(+)/H(+) exchange regulatory cofactor NHE... 57.8 2e-07
sp|Q9Z0J4|NOS1_MOUSE Nitric oxide synthase 1 OS=Mus musculus OX=1... 58.1 2e-07
sp|P29476|NOS1_RAT Nitric oxide synthase 1 OS=Rattus norvegicus O... 58.1 2e-07
sp|O96018|APBA3_HUMAN Amyloid-beta A4 precursor protein-binding f... 57.8 2e-07
sp|Q64010|CRK_MOUSE Adapter molecule crk OS=Mus musculus OX=10090... 56.6 2e-07
sp|Q71M21|RH21B_XENLA Rho GTPase-activating protein 21-B OS=Xenop... 58.1 2e-07
sp|A6QLK6|GRAP_BOVIN GRB2-related adapter protein OS=Bos taurus O... 55.4 3e-07
sp|Q9JJ40|NHRF3_RAT Na(+)/H(+) exchange regulatory cofactor NHE-R... 57.4 3e-07
sp|Q865P3|NHRF3_RABIT Na(+)/H(+) exchange regulatory cofactor NHE... 57.4 3e-07
sp|Q9JI92|SDCB1_RAT Syntenin-1 OS=Rattus norvegicus OX=10116 GN=S... 56.2 3e-07
sp|Q6DFG0|RH21A_XENLA Rho GTPase-activating protein 21-A OS=Xenop... 57.8 3e-07
sp|A2RUV4|RHG21_XENTR Rho GTPase-activating protein 21 OS=Xenopus... 57.8 3e-07
sp|Q96RT1|ERBIN_HUMAN Erbin OS=Homo sapiens OX=9606 GN=ERBIN PE=1... 57.8 3e-07
sp|Q8R4T5|GRASP_RAT General receptor for phosphoinositides 1-asso... 56.6 4e-07
sp|P55196|AFAD_HUMAN Afadin OS=Homo sapiens OX=9606 GN=AFDN PE=1 ... 57.4 4e-07
sp|E7RAI2|SHO1_OGAPD High osmolarity signaling protein SHO1 OS=Og... 55.4 5e-07
sp|O62677|IL16_SAISC Pro-interleukin-16 OS=Saimiri sciureus OX=95... 56.6 5e-07
sp|O70248|APBA3_RAT Amyloid-beta A4 precursor protein-binding fam... 56.6 5e-07
sp|Q2GT05|HSE1_CHAGB Class E vacuolar protein-sorting machinery p... 57.0 5e-07
sp|P87378|CRK_XENLA Adapter molecule crk OS=Xenopus laevis OX=835... 55.4 5e-07
sp|Q9JJA9|GRASP_MOUSE General receptor for phosphoinositides 1-as... 55.8 6e-07
sp|Q0QWG9|GRD2I_MOUSE Delphilin OS=Mus musculus OX=10090 GN=Grid2... 57.0 6e-07
sp|Q5RBI7|PDZD7_PONAB PDZ domain-containing protein 7 OS=Pongo ab... 56.6 6e-07
sp|P98084|APBA2_MOUSE Amyloid-beta A4 precursor protein-binding f... 56.6 6e-07
sp|Q80TH2|ERBIN_MOUSE Erbin OS=Mus musculus OX=10090 GN=Erbin PE=... 56.6 6e-07
sp|Q6C2N2|HSE1_YARLI Class E vacuolar protein-sorting machinery p... 56.2 7e-07
sp|Q11C47|PHNN_CHESB Ribose 1,5-bisphosphate phosphokinase PhnN O... 53.9 8e-07
sp|O88811|STAM2_MOUSE Signal transducing adapter molecule 2 OS=Mu... 55.8 8e-07
sp|O54824|IL16_MOUSE Pro-interleukin-16 OS=Mus musculus OX=10090 ... 56.2 8e-07
sp|O88888|APBA3_MOUSE Amyloid-beta A4 precursor protein-binding f... 55.8 9e-07
sp|Q9V9J3|SRC42_DROME Tyrosine-protein kinase Src42A OS=Drosophil... 55.8 1e-06
sp|Q4KL35|MAGIX_MOUSE PDZ domain-containing protein MAGIX OS=Mus ... 55.1 1e-06
sp|E3HQ85|PHNN_ACHXA Ribose 1,5-bisphosphate phosphokinase PhnN O... 53.1 1e-06
sp|Q9H5P4|PDZD7_HUMAN PDZ domain-containing protein 7 OS=Homo sap... 55.8 1e-06
sp|Q0V8R5|IL16_BOVIN Pro-interleukin-16 OS=Bos taurus OX=9913 GN=... 55.4 1e-06
sp|Q9H6Y5|MAGIX_HUMAN PDZ domain-containing protein MAGIX OS=Homo... 54.7 1e-06
sp|Q14005|IL16_HUMAN Pro-interleukin-16 OS=Homo sapiens OX=9606 G... 55.8 1e-06
sp|Q99767|APBA2_HUMAN Amyloid-beta A4 precursor protein-binding f... 55.4 1e-06
sp|O62674|IL16_CHLAE Pro-interleukin-16 OS=Chlorocebus aethiops O... 55.4 1e-06
sp|O35431|APBA2_RAT Amyloid-beta A4 precursor protein-binding fam... 55.4 1e-06
sp|Q6DFV3|RHG21_MOUSE Rho GTPase-activating protein 21 OS=Mus mus... 55.8 1e-06
sp|O62676|IL16_MACFA Pro-interleukin-16 OS=Macaca fascicularis OX... 55.4 1e-06
sp|Q5RD33|APBA2_PONAB Amyloid-beta A4 precursor protein-binding f... 55.4 1e-06
sp|O62675|IL16_MACMU Pro-interleukin-16 OS=Macaca mulatta OX=9544... 55.4 1e-06
sp|Q13588|GRAP_HUMAN GRB2-related adapter protein OS=Homo sapiens... 53.1 1e-06
sp|Q8CSK8|CTPAL_STAES Probable CtpA-like serine protease OS=Staph... 55.1 1e-06
sp|Q5HPB7|CTPAL_STAEQ Probable CtpA-like serine protease OS=Staph... 55.1 1e-06
sp|A7UA95|RADIL_DANRE Ras-associating and dilute domain-containin... 55.4 1e-06
sp|Q69Z89|RADIL_MOUSE Ras-associating and dilute domain-containin... 55.4 1e-06
sp|O08774|RGS12_RAT Regulator of G-protein signaling 12 OS=Rattus... 55.4 2e-06
sp|Q7A5M9|CTPAL_STAAN Probable CtpA-like serine protease OS=Staph... 54.7 2e-06
sp|Q99U67|CTPAL_STAAM Probable CtpA-like serine protease OS=Staph... 54.7 2e-06
sp|A8MUH7|PDZ1P_HUMAN Putative PDZ domain-containing protein PDZK... 54.3 2e-06
sp|Q22366|RIM_CAEEL Rab-3-interacting molecule unc-10 OS=Caenorha... 55.1 2e-06
sp|Q9JIL4|NHRF3_MOUSE Na(+)/H(+) exchange regulatory cofactor NHE... 54.7 2e-06
sp|O17583|LIN10_CAEEL Protein lin-10 OS=Caenorhabditis elegans OX... 55.1 2e-06
sp|Q5T5U3|RHG21_HUMAN Rho GTPase-activating protein 21 OS=Homo sa... 55.1 2e-06
sp|Q2YXZ9|CTPAL_STAAB Probable CtpA-like serine protease OS=Staph... 54.3 2e-06
sp|P42690|SRK4_SPOLA Tyrosine-protein kinase isoform SRK4 OS=Spon... 54.3 3e-06
sp|Q6GGY8|CTPAL_STAAR Probable CtpA-like serine protease OS=Staph... 54.3 3e-06
sp|O62666|IL16_PANTR Pro-interleukin-16 OS=Pan troglodytes OX=959... 54.3 3e-06
sp|Q7Z6J2|GRASP_HUMAN Protein TAMALIN OS=Homo sapiens OX=9606 GN=... 53.9 3e-06
sp|Q8NWR2|CTPAL_STAAW Probable CtpA-like serine protease OS=Staph... 54.3 3e-06
sp|Q6G9E1|CTPAL_STAAS Probable CtpA-like serine protease OS=Staph... 54.3 3e-06
sp|Q5HG01|CTPAL_STAAC Probable CtpA-like serine protease OS=Staph... 54.3 3e-06
sp|Q09284|YQJ3_CAEEL PDZ domain-containing protein C52A11.3 OS=Ca... 50.4 3e-06
sp|Q62083|PICK1_MOUSE PRKCA-binding protein OS=Mus musculus OX=10... 53.9 3e-06
sp|P42686|SRK1_SPOLA Tyrosine-protein kinase isoform SRK1 OS=Spon... 53.9 3e-06
sp|O35274|NEB2_RAT Neurabin-2 OS=Rattus norvegicus OX=10116 GN=Pp... 54.3 3e-06
sp|Q6R891|NEB2_MOUSE Neurabin-2 OS=Mus musculus OX=10090 GN=Ppp1r... 54.3 3e-06
sp|Q5T2W1|NHRF3_HUMAN Na(+)/H(+) exchange regulatory cofactor NHE... 53.9 3e-06
sp|Q96SB3|NEB2_HUMAN Neurabin-2 OS=Homo sapiens OX=9606 GN=PPP1R9... 54.3 3e-06
sp|A1A5H8|YES_DANRE Tyrosine-protein kinase yes OS=Danio rerio OX... 53.9 3e-06
sp|B7WN72|SHANK_CAEEL Protein shank OS=Caenorhabditis elegans OX=... 54.3 3e-06
sp|Q557J6|DBNL_DICDI Drebrin-like protein OS=Dictyostelium discoi... 53.5 4e-06
sp|Q6IN97|FRP2L_HUMAN Putative protein FRMPD2-like OS=Homo sapien... 53.1 4e-06
sp|Q9EP80|PICK1_RAT PRKCA-binding protein OS=Rattus norvegicus OX... 53.5 4e-06
sp|Q5RCF7|NHRF3_PONAB Na(+)/H(+) exchange regulatory cofactor NHE... 53.5 4e-06
sp|Q2T9M1|PICK1_BOVIN PRKCA-binding protein OS=Bos taurus OX=9913... 53.5 4e-06
sp|Q5REH1|PICK1_PONAB PRKCA-binding protein OS=Pongo abelii OX=96... 53.5 4e-06
sp|Q4R7Q5|PICK1_MACFA PRKCA-binding protein OS=Macaca fasciculari... 53.5 4e-06
sp|Q9NRD5|PICK1_HUMAN PRKCA-binding protein OS=Homo sapiens OX=96... 53.5 4e-06
sp|O75886|STAM2_HUMAN Signal transducing adapter molecule 2 OS=Ho... 53.5 4e-06
sp|Q8TEU7|RPGF6_HUMAN Rap guanine nucleotide exchange factor 6 OS... 53.9 5e-06
sp|Q99NE5|RIMS1_MOUSE Regulating synaptic membrane exocytosis pro... 53.9 5e-06
sp|Q8CGE9|RGS12_MOUSE Regulator of G-protein signaling 12 OS=Mus ... 53.9 5e-06
sp|Q86UT5|NHRF4_HUMAN Na(+)/H(+) exchange regulatory cofactor NHE... 53.5 5e-06
sp|P70441|NHRF1_MOUSE Na(+)/H(+) exchange regulatory cofactor NHE... 52.8 5e-06
sp|Q6CVA8|HSE1_KLULA Class E vacuolar protein-sorting machinery p... 53.1 5e-06
sp|Q92783|STAM1_HUMAN Signal transducing adapter molecule 1 OS=Ho... 53.1 6e-06
sp|Q9JIR4|RIMS1_RAT Regulating synaptic membrane exocytosis prote... 53.5 6e-06
sp|A2ALU4|SHRM2_MOUSE Protein Shroom2 OS=Mus musculus OX=10090 GN... 53.5 6e-06
sp|O61967|LAP1_CAEEL Protein lap1 OS=Caenorhabditis elegans OX=62... 53.1 7e-06
sp|O45539|SRC2_CAEEL Tyrosine protein-kinase src-2 OS=Caenorhabdi... 53.1 7e-06
sp|Q86UR5|RIMS1_HUMAN Regulating synaptic membrane exocytosis pro... 53.5 7e-06
sp|P34109|MYOD_DICDI Myosin ID heavy chain OS=Dictyostelium disco... 53.1 8e-06
sp|Q9JJ19|NHRF1_RAT Na(+)/H(+) exchange regulatory cofactor NHE-R... 52.4 8e-06
sp|P53667|LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapiens OX=9606... 52.8 8e-06
sp|O14924|RGS12_HUMAN Regulator of G-protein signaling 12 OS=Homo... 52.8 1e-05
sp|Q9Z0G0|GIPC1_MOUSE PDZ domain-containing protein GIPC1 OS=Mus ... 51.6 1e-05
sp|P13116|SRC2_XENLA Tyrosine-protein kinase Src-2 OS=Xenopus lae... 52.4 1e-05
sp|Q9QY39|PDZD4_MOUSE PDZ domain-containing protein 4 OS=Mus musc... 52.4 1e-05
sp|Q28619|NHRF1_RABIT Na(+)/H(+) exchange regulatory cofactor NHE... 51.6 1e-05
sp|Q09506|TX1B3_CAEEL Tax1-binding protein 3 homolog OS=Caenorhab... 48.5 1e-05
sp|P13115|SRC1_XENLA Tyrosine-protein kinase Src-1 OS=Xenopus lae... 52.0 1e-05
sp|Q9Y566|SHAN1_HUMAN SH3 and multiple ankyrin repeat domains pro... 52.4 1e-05
sp|P25020|SRC_RSVH1 Tyrosine-protein kinase transforming protein ... 51.6 2e-05
sp|Q3SZK8|NHRF1_BOVIN Na(+)/H(+) exchange regulatory cofactor NHE... 51.2 2e-05
sp|Q17353|PAR3_CAEEL Partitioning defective protein 3 OS=Caenorha... 52.0 2e-05
sp|Q9Z254|GIPC1_RAT PDZ domain-containing protein GIPC1 OS=Rattus... 50.8 2e-05
sp|Q5XHY7|STAM2_RAT Signal transducing adapter molecule 2 OS=Ratt... 51.2 2e-05
sp|O14908|GIPC1_HUMAN PDZ domain-containing protein GIPC1 OS=Homo... 50.8 2e-05
sp|Q9P7E8|APP1_SCHPO Protein app1 OS=Schizosaccharomyces pombe (s... 51.6 2e-05
sp|P13406|FYN_XENLA Tyrosine-protein kinase Fyn OS=Xenopus laevis... 51.2 2e-05
sp|P00528|SRC64_DROME Tyrosine-protein kinase Src64B OS=Drosophil... 51.2 2e-05
sp|P54792|DVLP1_HUMAN Putative segment polarity protein dishevell... 51.6 2e-05
sp|Q02977|YRK_CHICK Proto-oncogene tyrosine-protein kinase Yrk OS... 51.2 2e-05
sp|Q08012|GRAP_DROME Growth factor receptor-bound protein 2 OS=Dr... 49.3 2e-05
sp|Q6YKA8|DRK_DROSI Protein E(sev)2B OS=Drosophila simulans OX=72... 49.3 2e-05
sp|P70297|STAM1_MOUSE Signal transducing adapter molecule 1 OS=Mu... 51.2 2e-05
sp|Q9Z0R4|ITSN1_MOUSE Intersectin-1 OS=Mus musculus OX=10090 GN=I... 51.6 3e-05
sp|O14640|DVL1_HUMAN Segment polarity protein dishevelled homolog... 51.2 3e-05
sp|P53669|LIMK1_RAT LIM domain kinase 1 OS=Rattus norvegicus OX=1... 51.2 3e-05
sp|Q4R6G4|NHRF1_MACFA Na(+)/H(+) exchange regulatory cofactor NHE... 50.4 3e-05
sp|Q9WV48|SHAN1_RAT SH3 and multiple ankyrin repeat domains prote... 51.6 3e-05
sp|Q7TNF8|RIMB1_MOUSE Peripheral-type benzodiazepine receptor-ass... 51.6 3e-05
sp|D3YZU1|SHAN1_MOUSE SH3 and multiple ankyrin repeat domains pro... 51.6 3e-05
sp|O14745|NHRF1_HUMAN Na(+)/H(+) exchange regulatory cofactor NHE... 50.4 3e-05
sp|Q9NZM3|ITSN2_HUMAN Intersectin-2 OS=Homo sapiens OX=9606 GN=IT... 51.2 3e-05
sp|P51141|DVL1_MOUSE Segment polarity protein dishevelled homolog... 50.8 3e-05
sp|Q9JMH9|MY18A_MOUSE Unconventional myosin-XVIIIa OS=Mus musculu... 51.2 3e-05
sp|Q5IS48|DVL1_PANTR Segment polarity protein dishevelled homolog... 50.8 3e-05
sp|D3ZFD0|MY18A_RAT Unconventional myosin-XVIIIa OS=Rattus norveg... 51.2 3e-05
sp|Q5JV73|FRPD3_HUMAN FERM and PDZ domain-containing protein 3 OS... 51.2 4e-05
sp|Q9WVB9|DVL1_RAT Segment polarity protein dishevelled homolog D... 50.8 4e-05
sp|O93436|STAM2_CHICK Signal transducing adapter molecule 2 OS=Ga... 50.4 4e-05
sp|Q6ZWJ1|STXB4_HUMAN Syntaxin-binding protein 4 OS=Homo sapiens ... 50.4 4e-05
sp|Q9WVE9|ITSN1_RAT Intersectin-1 OS=Rattus norvegicus OX=10116 G... 50.8 4e-05
sp|Q61062|DVL3_MOUSE Segment polarity protein dishevelled homolog... 50.4 4e-05
sp|Q92997|DVL3_HUMAN Segment polarity protein dishevelled homolog... 50.4 4e-05
sp|O01498|STAM1_CAEEL Signal transducing adapter molecule 1 OS=Ca... 50.1 4e-05
sp|Q6EWH2|FYNA_DANRE Tyrosine-protein kinase fyna OS=Danio rerio ... 50.4 5e-05
sp|P09324|YES_CHICK Tyrosine-protein kinase Yes OS=Gallus gallus ... 50.4 5e-05
sp|Q05AS8|DVL2_XENTR Segment polarity protein dishevelled homolog... 50.4 5e-05
sp|Q8MR31|SLIP1_DROME Slo-interacting protein 1 OS=Drosophila mel... 50.4 5e-05
sp|Q9CX99|GRAP_MOUSE GRB2-related adapter protein OS=Mus musculus... 48.5 5e-05
sp|P05480|SRC_MOUSE Proto-oncogene tyrosine-protein kinase Src OS... 50.1 5e-05
sp|Q9WUD9|SRC_RAT Proto-oncogene tyrosine-protein kinase Src OS=R... 50.1 5e-05
sp|P12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src OS... 50.1 5e-05
sp|P17713|STK_HYDVU Tyrosine-protein kinase STK OS=Hydra vulgaris... 50.1 5e-05
sp|Q9Z1T4|CNKR2_RAT Connector enhancer of kinase suppressor of ra... 50.4 5e-05
sp|Q80YA9|CNKR2_MOUSE Connector enhancer of kinase suppressor of ... 50.4 5e-05
sp|Q8WXI2|CNKR2_HUMAN Connector enhancer of kinase suppressor of ... 50.4 5e-05
sp|P51142|DVL2_XENLA Segment polarity protein dishevelled homolog... 50.1 6e-05
sp|A7E8B6|SLA1_SCLS1 Actin cytoskeleton-regulatory complex protei... 50.4 6e-05
sp|Q1JPZ3|SRC_DANRE Proto-oncogene tyrosine-protein kinase Src OS... 50.1 6e-05
sp|Q05876|FYN_CHICK Tyrosine-protein kinase Fyn OS=Gallus gallus ... 50.1 6e-05
sp|O14641|DVL2_HUMAN Segment polarity protein dishevelled homolog... 50.1 6e-05
sp|Q62844|FYN_RAT Tyrosine-protein kinase Fyn OS=Rattus norvegicu... 50.1 6e-05
sp|A1Y2K1|FYN_PIG Tyrosine-protein kinase Fyn OS=Sus scrofa OX=98... 50.1 6e-05
sp|P39688|FYN_MOUSE Tyrosine-protein kinase Fyn OS=Mus musculus O... 50.1 6e-05
sp|P06241|FYN_HUMAN Tyrosine-protein kinase Fyn OS=Homo sapiens O... 50.1 6e-05
sp|A0JNB0|FYN_BOVIN Tyrosine-protein kinase Fyn OS=Bos taurus OX=... 50.1 6e-05
sp|F1RDG9|FYNB_DANRE Tyrosine-protein kinase fynb OS=Danio rerio ... 50.1 6e-05
sp|Q96JH8|RADIL_HUMAN Ras-associating and dilute domain-containin... 50.1 7e-05
sp|Q60838|DVL2_MOUSE Segment polarity protein dishevelled homolog... 50.1 7e-05
sp|Q9WV89|STXB4_MOUSE Syntaxin-binding protein 4 OS=Mus musculus ... 49.7 7e-05
sp|Q10199|IMP2_SCHPO Septation protein imp2 OS=Schizosaccharomyce... 49.7 7e-05
sp|P53671|LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapiens OX=9606... 49.7 8e-05
sp|Q6DKE2|DVL3_XENLA Segment polarity protein dishevelled homolog... 49.7 8e-05
sp|Q76G19|PDZD4_HUMAN PDZ domain-containing protein 4 OS=Homo sap... 49.7 8e-05
sp|B1WAP7|DVL3_XENTR Segment polarity protein dishevelled homolog... 49.7 8e-05
sp|P46109|CRKL_HUMAN Crk-like protein OS=Homo sapiens OX=9606 GN=... 48.9 8e-05
sp|P53668|LIMK1_MOUSE LIM domain kinase 1 OS=Mus musculus OX=1009... 49.7 8e-05
sp|P38753|HSE1_YEAST Class E vacuolar protein-sorting machinery p... 49.3 9e-05
sp|O54785|LIMK2_MOUSE LIM domain kinase 2 OS=Mus musculus OX=1009... 49.7 9e-05
sp|Q22227|MIG5_CAEEL Segment polarity protein dishevelled homolog... 49.7 9e-05
sp|P10936|YES_XENLA Tyrosine-protein kinase Yes OS=Xenopus laevis... 49.3 9e-05
sp|Q4P5J4|HSE1_USTMA Class E vacuolar protein-sorting machinery p... 49.3 1e-04
sp|F1LM93|YES_RAT Tyrosine-protein kinase Yes OS=Rattus norvegicu... 49.3 1e-04
sp|Q04736|YES_MOUSE Tyrosine-protein kinase Yes OS=Mus musculus O... 49.3 1e-04
sp|P07947|YES_HUMAN Tyrosine-protein kinase Yes OS=Homo sapiens O... 49.3 1e-04
sp|P63185|SRC_RSVSE Tyrosine-protein kinase transforming protein ... 49.3 1e-04
sp|Q9EQZ7|RIMS2_MOUSE Regulating synaptic membrane exocytosis pro... 49.7 1e-04
sp|Q9UQ26|RIMS2_HUMAN Regulating synaptic membrane exocytosis pro... 49.3 1e-04
sp|Q9JIS1|RIMS2_RAT Regulating synaptic membrane exocytosis prote... 49.3 1e-04
sp|P00525|SRC_AVISR Tyrosine-protein kinase transforming protein ... 48.9 1e-04
sp|P00523|SRC_CHICK Proto-oncogene tyrosine-protein kinase Src OS... 48.9 1e-04
sp|E1JIT7|PSD_DROME PH and SEC7 domain-containing protein OS=Dros... 49.3 1e-04
sp|Q4P9Q7|SHO1_USTMA High osmolarity signaling protein SHO1 OS=Us... 48.5 1e-04
sp|P14084|SRC_AVISS Tyrosine-protein kinase transforming protein ... 48.9 1e-04
sp|Q9Z0R6|ITSN2_MOUSE Intersectin-2 OS=Mus musculus OX=10090 GN=I... 49.3 1e-04
sp|P15054|SRC_AVIS2 Tyrosine-protein kinase transforming protein ... 48.9 1e-04
sp|Q92614|MY18A_HUMAN Unconventional myosin-XVIIIa OS=Homo sapien... 49.3 1e-04
sp|P14234|FGR_MOUSE Tyrosine-protein kinase Fgr OS=Mus musculus O... 48.9 1e-04
sp|P27446|FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiphophorus he... 48.9 1e-04
sp|P14085|SRC_AVIST Tyrosine-protein kinase transforming protein ... 48.9 1e-04
sp|Q9XYM0|CRK_DROME Adapter molecule Crk OS=Drosophila melanogast... 47.7 1e-04
sp|Q9PU47|PDLI3_CHICK PDZ and LIM domain protein 3 OS=Gallus gall... 48.1 1e-04
sp|P28191|PTP1_CAEEL Tyrosine-protein phosphatase 1 OS=Caenorhabd... 49.3 1e-04
sp|Q75DS3|HSE1_EREGS Class E vacuolar protein-sorting machinery p... 48.5 1e-04
sp|Q99JZ0|SDCB2_MOUSE Syntenin-2 OS=Mus musculus OX=10090 GN=Sdcb... 47.7 2e-04
sp|P00524|SRC_RSVSA Tyrosine-protein kinase transforming protein ... 48.5 2e-04
sp|Q61085|RHPN1_MOUSE Rhophilin-1 OS=Mus musculus OX=10090 GN=Rhp... 48.5 2e-04
sp|P26045|PTN3_HUMAN Tyrosine-protein phosphatase non-receptor ty... 48.9 2e-04
sp|O42287|ITSN1_XENLA Intersectin-1 OS=Xenopus laevis OX=8355 GN=... 48.9 2e-04
sp|P47941|CRKL_MOUSE Crk-like protein OS=Mus musculus OX=10090 GN... 47.7 2e-04
sp|Q6P9H4|CNKR3_HUMAN Connector enhancer of kinase suppressor of ... 48.5 2e-04
sp|Q8TCX5|RHPN1_HUMAN Rhophilin-1 OS=Homo sapiens OX=9606 GN=RHPN... 48.5 2e-04
sp|P00526|SRC_RSVP Tyrosine-protein kinase transforming protein S... 48.1 2e-04
sp|P00527|YES_AVISY Tyrosine-protein kinase transforming protein ... 48.1 2e-04
sp|O35002|CTPB_BACSU Carboxy-terminal processing protease CtpB OS... 48.1 2e-04
sp|O34666|CTPA_BACSU Carboxy-terminal processing protease CtpA OS... 48.1 2e-04
sp|E7A253|SHO1_SPORE High osmolarity signaling protein SHO1 OS=Sp... 47.7 2e-04
sp|F1PBJ0|RPGF2_CANLF Rap guanine nucleotide exchange factor 2 OS... 48.5 2e-04
sp|Q15811|ITSN1_HUMAN Intersectin-1 OS=Homo sapiens OX=9606 GN=IT... 48.5 2e-04
sp|Q5SGD7|CNKR3_RAT Connector enhancer of kinase suppressor of ra... 48.1 2e-04
sp|Q9Y4G8|RPGF2_HUMAN Rap guanine nucleotide exchange factor 2 OS... 48.5 2e-04
sp|O42565|LIMK1_XENLA LIM domain kinase 1 OS=Xenopus laevis OX=83... 48.1 2e-04
sp|A2ALK8|PTN3_MOUSE Tyrosine-protein phosphatase non-receptor ty... 48.1 2e-04
sp|O95153|RIMB1_HUMAN Peripheral-type benzodiazepine receptor-ass... 48.5 3e-04
sp|Q1IHU1|MIAA_KORVE tRNA dimethylallyltransferase OS=Koribacter ... 47.4 3e-04
sp|Q578K3|FBPC_BRUAB Fe(3+) ions import ATP-binding protein FbpC ... 47.4 3e-04
sp|Q2YKX3|FBPC_BRUA2 Fe(3+) ions import ATP-binding protein FbpC ... 47.4 3e-04
sp|Q8WWI1|LMO7_HUMAN LIM domain only protein 7 OS=Homo sapiens OX... 48.1 3e-04
sp|Q9VCX1|RGS_DROME Regulator of G-protein signaling loco OS=Dros... 48.1 3e-04
sp|Q8BMA3|CNKR3_MOUSE Connector enhancer of kinase suppressor of ... 47.7 3e-04
sp|Q9NZN5|ARHGC_HUMAN Rho guanine nucleotide exchange factor 12 O... 48.1 3e-04
sp|P09769|FGR_HUMAN Tyrosine-protein kinase Fgr OS=Homo sapiens O... 47.7 3e-04
sp|Q14511|CASL_HUMAN Enhancer of filamentation 1 OS=Homo sapiens ... 47.7 3e-04
sp|G9CGD6|CNIPF_HUMAN CNK3/IPCEF1 fusion protein OS=Homo sapiens ... 47.7 3e-04
sp|O15085|ARHGB_HUMAN Rho guanine nucleotide exchange factor 11 O... 48.1 3e-04
sp|Q6FN49|HSE1_CANGA Class E vacuolar protein-sorting machinery p... 47.4 3e-04
sp|Q99MJ6|NHRF4_MOUSE Na(+)/H(+) exchange regulatory cofactor NHE... 47.4 4e-04
sp|Q2K8C8|FBPC_RHIEC Fe(3+) ions import ATP-binding protein FbpC ... 47.0 4e-04
sp|Q92WJ0|FBPC1_RHIME Fe(3+) ions import ATP-binding protein FbpC... 47.0 4e-04
sp|P42681|TXK_HUMAN Tyrosine-protein kinase TXK OS=Homo sapiens O... 47.4 4e-04
sp|Q8R4H2|ARHGC_MOUSE Rho guanine nucleotide exchange factor 12 O... 47.7 4e-04
sp|P42784|CTPA_PICP2 Carboxyl-terminal-processing protease OS=Pic... 47.0 4e-04
sp|O75791|GRAP2_HUMAN GRB2-related adapter protein 2 OS=Homo sapi... 47.0 4e-04
sp|P42522|MYOC_DICDI Myosin IC heavy chain OS=Dictyostelium disco... 47.7 4e-04
sp|Q4KLN0|SDCB2_RAT Syntenin-2 OS=Rattus norvegicus OX=10116 GN=S... 46.6 4e-04
sp|B1LY53|PHNN_METRJ Ribose 1,5-bisphosphate phosphokinase PhnN O... 45.0 4e-04
sp|O89100|GRAP2_MOUSE GRB2-related adaptor protein 2 OS=Mus muscu... 46.6 4e-04
sp|Q14155|ARHG7_HUMAN Rho guanine nucleotide exchange factor 7 OS... 47.4 5e-04
sp|Q6DJJ6|RHN2A_XENLA Rhophilin-2-A OS=Xenopus laevis OX=8355 GN=... 47.4 5e-04
sp|B8D5U4|KCY_DESA1 Cytidylate kinase OS=Desulfurococcus amylolyt... 45.4 5e-04
sp|P53670|LIMK2_RAT LIM domain kinase 2 OS=Rattus norvegicus OX=1... 47.4 5e-04
sp|Q28923|YES_CANLF Tyrosine-protein kinase Yes OS=Canis lupus fa... 47.0 5e-04
sp|Q6P6U0|FGR_RAT Tyrosine-protein kinase Fgr OS=Rattus norvegicu... 47.0 5e-04
sp|E9Q634|MYO1E_MOUSE Unconventional myosin-Ie OS=Mus musculus OX... 47.4 5e-04
sp|Q5U2U2|CRKL_RAT Crk-like protein OS=Rattus norvegicus OX=10116... 46.2 5e-04
sp|Q9QY53|NPHP1_MOUSE Nephrocystin-1 OS=Mus musculus OX=10090 GN=... 47.0 5e-04
sp|P42682|TXK_MOUSE Tyrosine-protein kinase TXK OS=Mus musculus O... 47.0 5e-04
sp|Q8U6M1|FBPC_AGRFC Fe(3+) ions import ATP-binding protein FbpC ... 46.6 5e-04
sp|Q9ES28|ARHG7_MOUSE Rho guanine nucleotide exchange factor 7 OS... 47.0 6e-04
sp|O74749|HSE1_SCHPO Class E vacuolar protein-sorting machinery p... 46.6 6e-04
sp|Q8IR79|LIMK1_DROME LIM domain kinase 1 OS=Drosophila melanogas... 47.0 6e-04
sp|Q9ES67|ARHGB_RAT Rho guanine nucleotide exchange factor 11 OS=... 47.0 6e-04
sp|Q5L4W4|DER_CHLAB GTPase Der OS=Chlamydia abortus (strain DSM 2... 46.6 6e-04
sp|Q8TF64|GIPC3_HUMAN PDZ domain-containing protein GIPC3 OS=Homo... 46.2 6e-04
sp|Q8JH64|BTK_CHICK Tyrosine-protein kinase BTK OS=Gallus gallus ... 46.6 6e-04
sp|Q256C5|DER_CHLFF GTPase Der OS=Chlamydia felis (strain Fe/C-56... 46.6 7e-04
sp|P43669|PRC_SALTY Tail-specific protease OS=Salmonella typhimur... 46.6 7e-04
sp|C1D7Y5|PHNN_LARHH Ribose 1,5-bisphosphate phosphokinase PhnN O... 46.2 8e-04
sp|A0A8I3PDQ1|CASL_CANLF Enhancer of filamentation 1 OS=Canis lup... 46.6 8e-04
sp|Q5SYB0|FRPD1_HUMAN FERM and PDZ domain-containing protein 1 OS... 46.6 8e-04
sp|Q86NH1|SYD1_CAEEL Rho GTPase-activating protein syd-1 OS=Caeno... 46.6 8e-04
sp|B2TQ47|AROK_CLOBB Shikimate kinase OS=Clostridium botulinum (s... 44.3 9e-04
sp|P53666|LIMK2_CHICK LIM domain kinase 2 OS=Gallus gallus OX=903... 46.2 0.001
sp|Q22638|MICS1_CAEEL Mitochondrial scaffolding protein 1 OS=Caen... 45.4 0.001
sp|P45306|PRC_HAEIN Tail-specific protease OS=Haemophilus influen... 46.2 0.001
sp|O35177|CASL_MOUSE Enhancer of filamentation 1 OS=Mus musculus ... 46.2 0.001
sp|Q9ULL8|SHRM4_HUMAN Protein Shroom4 OS=Homo sapiens OX=9606 GN=... 46.2 0.001
sp|Q821L7|DER_CHLCV GTPase Der OS=Chlamydia caviae (strain ATCC V... 45.8 0.001
sp|Q8R1G6|PDLI2_MOUSE PDZ and LIM domain protein 2 OS=Mus musculu... 45.4 0.001
sp|Q5I0L6|CYTIP_RAT Cytohesin-interacting protein OS=Rattus norve... 45.4 0.001
sp|G5EEW9|CNKR_CAEEL Connector enhancer of kinase suppressor of r... 46.2 0.001
sp|Q96JY6|PDLI2_HUMAN PDZ and LIM domain protein 2 OS=Homo sapien... 45.4 0.001
sp|Q6ZPF3|TIAM2_MOUSE Rho guanine nucleotide exchange factor TIAM... 46.2 0.001
sp|Q9JJS5|SH3B4_RAT SH3 domain-binding protein 4 OS=Rattus norveg... 46.2 0.001
sp|Q91VY6|CYTIP_MOUSE Cytohesin-interacting protein OS=Mus muscul... 45.4 0.001
sp|Q60592|MAST2_MOUSE Microtubule-associated serine/threonine-pro... 46.2 0.001
sp|A1ZA47|ZASP_DROME PDZ and LIM domain protein Zasp OS=Drosophil... 46.2 0.001
sp|Q8R5M0|GIPC3_MOUSE PDZ domain-containing protein GIPC3 OS=Mus ... 45.0 0.001
sp|Q9P864|SHO1_CYBJA High osmolarity signaling protein SHO1 OS=Cy... 45.0 0.001
sp|Q6P0Q8|MAST2_HUMAN Microtubule-associated serine/threonine-pro... 46.2 0.001
sp|B8R1V5|SHO1_CLALS High osmolarity signaling protein SHO1 OS=Cl... 45.0 0.001
sp|C4Y1G1|SHO1_CLAL4 High osmolarity signaling protein SHO1 OS=Cl... 45.0 0.001
sp|O84709|DER_CHLTR GTPase Der OS=Chlamydia trachomatis (strain D... 45.4 0.001
sp|Q3KKZ1|DER_CHLTA GTPase Der OS=Chlamydia trachomatis serovar A... 45.4 0.001
sp|Q811L6|MAST4_MOUSE Microtubule-associated serine/threonine-pro... 46.2 0.001
sp|Q0SS84|RSGA_CLOPS Small ribosomal subunit biogenesis GTPase Rs... 45.0 0.001
sp|Q80U40|RIMB2_MOUSE RIMS-binding protein 2 OS=Mus musculus OX=1... 45.8 0.001
sp|P23865|PRC_ECOLI Tail-specific protease OS=Escherichia coli (s... 45.8 0.001
sp|Q1LVQ2|SH34A_DANRE SH3 domain-binding protein 4-A OS=Danio rer... 45.8 0.001
sp|Q4P3H6|SLA1_USTMA Actin cytoskeleton-regulatory complex protei... 45.8 0.002
sp|A0A142I732|PHOO2_DIALO ABC-type transporter phomO' OS=Diaporth... 45.8 0.002
sp|F4KHG6|CTPA1_ARATH Carboxyl-terminal-processing peptidase 1, c... 45.4 0.002
sp|Q63ZR5|RHN2B_XENLA Rhophilin-2-B OS=Xenopus laevis OX=8355 GN=... 45.4 0.002
sp|Q09666|AHNK_HUMAN Neuroblast differentiation-associated protei... 45.8 0.002
sp|O60759|CYTIP_HUMAN Cytohesin-interacting protein OS=Homo sapie... 45.0 0.002
sp|Q9GKU1|PDLI2_MACFA PDZ and LIM domain protein 2 OS=Macaca fasc... 44.7 0.002
sp|Q921I6|SH3B4_MOUSE SH3 domain-binding protein 4 OS=Mus musculu... 45.4 0.002
sp|Q32L23|LIMK2_BOVIN LIM domain kinase 2 OS=Bos taurus OX=9913 G... 45.0 0.002
sp|Q1W617|SHRM4_MOUSE Protein Shroom4 OS=Mus musculus OX=10090 GN... 45.4 0.002
sp|G5EDM4|NHRF1_CAEEL Na(+)/H(+) exchange regulatory cofactor-lik... 45.0 0.002
sp|O55043|ARHG7_RAT Rho guanine nucleotide exchange factor 7 OS=R... 45.0 0.002
sp|Q9P0V3|SH3B4_HUMAN SH3 domain-binding protein 4 OS=Homo sapien... 45.4 0.002
sp|F1MSG6|RPGF2_BOVIN Rap guanine nucleotide exchange factor 2 OS... 45.4 0.002
sp|O15021|MAST4_HUMAN Microtubule-associated serine/threonine-pro... 45.4 0.002
sp|O15034|RIMB2_HUMAN RIMS-binding protein 2 OS=Homo sapiens OX=9... 45.0 0.002
sp|A5DR93|SHO1_PICGU High osmolarity signaling protein SHO1 OS=Me... 44.3 0.002
sp|B0BAF8|DER_CHLTB GTPase Der OS=Chlamydia trachomatis serovar L... 44.7 0.002
sp|B0B8S9|DER_CHLT2 GTPase Der OS=Chlamydia trachomatis serovar L... 44.7 0.002
sp|Q6CHN0|SLA1_YARLI Actin cytoskeleton-regulatory complex protei... 45.0 0.003
sp|A8XI74|CED2_CAEBR Cell death abnormality protein 2 OS=Caenorha... 43.9 0.003
sp|G5EE56|SRC1_CAEEL Tyrosine protein-kinase src-1 OS=Caenorhabdi... 44.7 0.003
sp|A3LXQ8|HSE1_PICST Class E vacuolar protein-sorting machinery p... 44.7 0.003
sp|F1M386|RPGF2_RAT Rap guanine nucleotide exchange factor 2 OS=R... 45.0 0.003
sp|Q895P5|RSGA_CLOTE Small ribosomal subunit biogenesis GTPase Rs... 43.9 0.003
sp|Q8FVV5|FBPC_BRUSU Fe(3+) ions import ATP-binding protein FbpC ... 44.3 0.003
sp|Q6NU22|SH34A_XENLA SH3 domain-binding protein 4-A OS=Xenopus l... 44.7 0.003
sp|Q09822|CDC15_SCHPO Cell division control protein 15 OS=Schizos... 44.7 0.003
sp|Q8CHG7|RPGF2_MOUSE Rap guanine nucleotide exchange factor 2 OS... 44.7 0.003
sp|Q9QWY8|ASAP1_MOUSE Arf-GAP with SH3 domain, ANK repeat and PH ... 44.7 0.003
sp|Q5A895|HSE1_CANAL Class E vacuolar protein-sorting machinery p... 44.3 0.003
sp|P70248|MYO1F_MOUSE Unconventional myosin-If OS=Mus musculus OX... 44.7 0.003
sp|Q9JIR0|RIMB1_RAT Peripheral-type benzodiazepine receptor-assoc... 44.7 0.003
sp|Q75JD4|Y1676_DICDI SH3 and F-BAR domain-containing protein DDB... 44.3 0.003
sp|P41239|CSK_CHICK Tyrosine-protein kinase CSK OS=Gallus gallus ... 44.3 0.003
sp|P73940|HHOB_SYNY3 Putative serine protease HhoB OS=Synechocyst... 44.3 0.003
sp|Q9D9M4|PDZD9_MOUSE PDZ domain-containing protein 9 OS=Mus musc... 43.5 0.004
sp|Q32KW7|PDZD9_BOVIN PDZ domain-containing protein 9 OS=Bos taur... 43.5 0.004
sp|P06239|LCK_HUMAN Tyrosine-protein kinase Lck OS=Homo sapiens O... 44.3 0.004
sp|Q7SGL6|SHO1_NEUCR High osmolarity signaling protein sho1 OS=Ne... 43.5 0.004
sp|Q8XJL9|RSGA_CLOPE Small ribosomal subunit biogenesis GTPase Rs... 43.5 0.004
sp|Q13882|PTK6_HUMAN Protein-tyrosine kinase 6 OS=Homo sapiens OX... 43.9 0.004
sp|Q12965|MYO1E_HUMAN Unconventional myosin-Ie OS=Homo sapiens OX... 44.3 0.004
sp|Q97B38|KAD6_THEVO Putative adenylate kinase OS=Thermoplasma vo... 42.0 0.004
sp|E3QNZ1|SHO1_COLGM High osmolarity signaling protein SHO1 OS=Co... 43.5 0.004
sp|Q9ULD6|INTU_HUMAN Protein inturned OS=Homo sapiens OX=9606 GN=... 44.3 0.004
sp|B1V8A0|SH3GH_CAEEL Endophilin-A homolog OS=Caenorhabditis eleg... 43.5 0.004
sp|Q0TPL7|RSGA_CLOP1 Small ribosomal subunit biogenesis GTPase Rs... 43.1 0.004
sp|C9SA05|SHO1_VERA1 High osmolarity signaling protein SHO1 OS=Ve... 43.1 0.005
sp|F4J3G5|CTPA3_ARATH Carboxyl-terminal-processing peptidase 3, c... 43.9 0.005
sp|Q810W7|MAST1_RAT Microtubule-associated serine/threonine-prote... 44.3 0.005
sp|Q9R1L5|MAST1_MOUSE Microtubule-associated serine/threonine-pro... 44.3 0.005
sp|Q3T0C8|PDLI2_BOVIN PDZ and LIM domain protein 2 OS=Bos taurus ... 43.5 0.005
sp|Q62420|SH3G2_MOUSE Endophilin-A1 OS=Mus musculus OX=10090 GN=S... 43.5 0.005
sp|Q498M5|SH3R2_RAT E3 ubiquitin-protein ligase SH3RF2 OS=Rattus ... 43.9 0.005
sp|Q6AX33|MAST3_XENLA Microtubule-associated serine/threonine-pro... 43.9 0.005
sp|Q8IPW2|NCK_DROME SH2/SH3 adapter protein dreadlocks OS=Drosoph... 43.9 0.005
sp|Q63356|MYO1E_RAT Unconventional myosin-Ie OS=Rattus norvegicus... 43.9 0.005
sp|C5MB30|SHO1_CANTT High osmolarity signaling protein SHO1 OS=Ca... 43.5 0.005
sp|Q8QFX1|RIMB2_CHICK RIMS-binding protein 2 OS=Gallus gallus OX=... 43.9 0.005
sp|Q64434|PTK6_MOUSE Protein-tyrosine kinase 6 OS=Mus musculus OX... 43.5 0.005
sp|Q8AXQ3|SH3B4_SERQU SH3 domain-binding protein 4 OS=Seriola qui... 43.9 0.005
sp|Q6AYD6|PDLI2_RAT PDZ and LIM domain protein 2 OS=Rattus norveg... 43.1 0.005
sp|Q6BNP6|HSE1_DEBHA Class E vacuolar protein-sorting machinery p... 43.5 0.006
sp|Q8IVF5|TIAM2_HUMAN Rho guanine nucleotide exchange factor TIAM... 43.9 0.006
sp|Q6NU51|SH34B_XENLA SH3 domain-binding protein 4-B OS=Xenopus l... 43.9 0.006
sp|C4YDC4|SHO1_CANAW High osmolarity signaling protein SHO1 OS=Ca... 43.5 0.006
sp|Q5AQ36|SHO1_CANAL High osmolarity signaling protein SHO1 OS=Ca... 43.5 0.006
sp|Q9NHC3|CED2_CAEEL Cell death abnormality protein 2 OS=Caenorha... 42.7 0.006
sp|C7Z504|SHO1_FUSV7 High osmolarity signaling protein SHO1 OS=Fu... 43.1 0.006
sp|B9W8T5|SHO1_CANDC High osmolarity signaling protein SHO1 OS=Ca... 43.5 0.006
sp|A9A0U3|MIAA_DESOH tRNA dimethylallyltransferase OS=Desulfosudi... 43.1 0.006
sp|Q7RX59|ATM1_NEUCR Iron-sulfur clusters transporter atm1, mitoc... 43.5 0.006
sp|Q059U7|INTU_MOUSE Protein inturned OS=Mus musculus OX=10090 GN... 43.5 0.007
sp|Q8X6U5|UGPC_ECO57 sn-glycerol-3-phosphate import ATP-binding p... 43.1 0.007
sp|Q8AXV1|SH3G2_CHICK Endophilin-A1 OS=Gallus gallus OX=9031 GN=S... 43.1 0.007
sp|B3EQM3|MIAA_CHLPB tRNA dimethylallyltransferase OS=Chlorobium ... 42.7 0.007
sp|Q2W8Q8|MAME_MAGSA Magnetosome formation protease MamE OS=Magne... 43.5 0.007
sp|Q9Y2H9|MAST1_HUMAN Microtubule-associated serine/threonine-pro... 43.5 0.007
sp|Q9PL97|DEGPL_CHLMU Probable periplasmic serine endoprotease De... 43.1 0.007
sp|Q5LLN2|COAE_RUEPO Dephospho-CoA kinase OS=Ruegeria pomeroyi (s... 42.0 0.008
sp|P31693|SRC_RSVPA Tyrosine-protein kinase transforming protein ... 43.1 0.008
sp|B8MD74|SHO1_TALSN High osmolarity signaling protein sho1 OS=Ta... 42.4 0.008
sp|Q5U228|SH3B4_XENTR SH3 domain-binding protein 4 OS=Xenopus tro... 43.5 0.008
sp|A0A8J9WHR9|PHOO1_DIALO ABC-type transporter phomO OS=Diaporthe... 43.5 0.008
sp|B1I462|DER_DESAP GTPase Der OS=Desulforudis audaxviator (strai... 43.1 0.008
sp|A4SK24|AROK_AERS4 Shikimate kinase OS=Aeromonas salmonicida (s... 41.2 0.008
sp|A0KN29|AROK_AERHH Shikimate kinase OS=Aeromonas hydrophila sub... 41.2 0.008
sp|A5E1V8|SHO1_LODEL High osmolarity signaling protein SHO1 OS=Lo... 42.7 0.008
sp|Q8QFP8|LIMK1_CHICK LIM domain kinase 1 OS=Gallus gallus OX=903... 43.1 0.009
sp|Q95M30|HCK_MACFA Tyrosine-protein kinase HCK OS=Macaca fascicu... 43.1 0.009
sp|Q4R729|SH321_MACFA SH3 domain-containing protein 21 OS=Macaca ... 43.1 0.009
sp|P32577|CSK_RAT Tyrosine-protein kinase CSK OS=Rattus norvegicu... 42.7 0.009
sp|P41241|CSK_MOUSE Tyrosine-protein kinase CSK OS=Mus musculus O... 42.7 0.009
sp|P41240|CSK_HUMAN Tyrosine-protein kinase CSK OS=Homo sapiens O... 42.7 0.009
sp|Q0VBZ0|CSK_BOVIN Tyrosine-protein kinase CSK OS=Bos taurus OX=... 42.7 0.009
sp|Q9H987|SYP2L_HUMAN Synaptopodin 2-like protein OS=Homo sapiens... 43.1 0.010
sp|Q2QV81|AB49G_ORYSJ ABC transporter G family member 49 OS=Oryza... 43.1 0.010
sp|Q9VU84|DBNL_DROME Drebrin-like protein OS=Drosophila melanogas... 42.7 0.010
sp|B2V5W6|DER_SULSY GTPase Der OS=Sulfurihydrogenibium sp. (strai... 42.7 0.010
sp|F4JT78|RPP2A_ARATH Disease resistance protein RPP2A OS=Arabido... 43.1 0.010
sp|D4ACE5|INTU_RAT Protein inturned OS=Rattus norvegicus OX=10116... 43.1 0.010
sp|F4KHH8|RPS6C_ARATH Disease resistance protein RPS6 OS=Arabidop... 43.1 0.010
sp|P35991|BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus musculus O... 42.7 0.010
sp|Q9PLM3|DER_CHLMU GTPase Der OS=Chlamydia muridarum (strain MoP... 42.7 0.011
sp|A0QSH8|KAD_MYCS2 Adenylate kinase OS=Mycolicibacterium smegmat... 41.2 0.011
sp|Q9NYB9|ABI2_HUMAN Abl interactor 2 OS=Homo sapiens OX=9606 GN=... 42.7 0.011
sp|Q9JIR1|RIMB2_RAT RIMS-binding protein 2 OS=Rattus norvegicus O... 42.7 0.012
sp|Q64XX2|MIAA1_BACFR tRNA dimethylallyltransferase 1 OS=Bacteroi... 42.0 0.012
sp|D8PSG0|SHO1_SCHCM High osmolarity signaling protein SHO1 OS=Sc... 42.0 0.012
sp|Q2KEW0|SHO1_PYRO7 Cell surface sensor SHO1 OS=Pyricularia oryz... 42.0 0.012
sp|O35179|SH3G2_RAT Endophilin-A1 OS=Rattus norvegicus OX=10116 G... 42.0 0.013
sp|Q5LH18|MIAA1_BACFN tRNA dimethylallyltransferase 1 OS=Bacteroi... 42.0 0.013
sp|Q99963|SH3G3_HUMAN Endophilin-A3 OS=Homo sapiens OX=9606 GN=SH... 42.0 0.013
sp|B4HEM8|HTRA2_DROSE Serine protease HTRA2, mitochondrial OS=Dro... 42.4 0.013
sp|Q9VFJ3|HTRA2_DROME Serine protease HTRA2, mitochondrial OS=Dro... 42.4 0.013
sp|B2THS4|RSGA_CLOBB Small ribosomal subunit biogenesis GTPase Rs... 42.0 0.013
sp|Q3IQI3|PSTB2_NATPD Phosphate import ATP-binding protein PstB 2... 42.0 0.013
sp|Q03E60|KTHY_PEDPA Thymidylate kinase OS=Pediococcus pentosaceu... 41.2 0.013
sp|Q91YE8|SYNP2_MOUSE Synaptopodin-2 OS=Mus musculus OX=10090 GN=... 42.7 0.014
sp|W6RTA4|CLA1_CAEEL Protein clarinet OS=Caenorhabditis elegans O... 42.7 0.014
sp|P34092|MYOB_DICDI Myosin IB heavy chain OS=Dictyostelium disco... 42.7 0.014
sp|Q1LU61|AROK_BAUCH Shikimate kinase OS=Baumannia cicadellinicol... 40.8 0.014
sp|Q8I1C0|SH3G3_DROPS Endophilin-A OS=Drosophila pseudoobscura ps... 42.0 0.014
sp|B4QZU6|HTRA2_DROSI Serine protease HTRA2, mitochondrial OS=Dro... 42.0 0.014
sp|P0DKH6|RPS6R_ARATH Disease resistance protein RPS6 OS=Arabidop... 42.4 0.015
sp|Q54FG5|GACJJ_DICDI Rho GTPase-activating protein gacJJ OS=Dict... 42.4 0.015
sp|Q06187|BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo sapiens O... 42.4 0.015
sp|P16333|NCK1_HUMAN SH2/SH3 adapter protein NCK1 OS=Homo sapiens... 42.0 0.016
sp|O14259|SFP47_SCHPO Ubp4-interactor sfp47 OS=Schizosaccharomyce... 42.0 0.016
sp|P18584|DEGPL_CHLTR Probable periplasmic serine endoprotease De... 42.0 0.016
sp|Q1AAU6|ASAP1_RAT Arf-GAP with SH3 domain, ANK repeat and PH do... 42.4 0.017
sp|Q8I190|SH3G3_DROVI Endophilin-A OS=Drosophila virilis OX=7244 ... 42.0 0.017
sp|P53281|LSB1_YEAST LAS seventeen-binding protein 1 OS=Saccharom... 41.2 0.017
sp|B9K8E0|DER_THENN GTPase Der OS=Thermotoga neapolitana (strain ... 42.0 0.017
sp|Q8ZH59|RSEP_YERPE Protease RseP OS=Yersinia pestis OX=632 GN=r... 42.0 0.018
sp|P50545|HCK_RAT Tyrosine-protein kinase HCK OS=Rattus norvegicu... 42.0 0.019
sp|A4FU49|SH321_HUMAN SH3 domain-containing protein 21 OS=Homo sa... 42.0 0.019
sp|Q63767|BCAR1_RAT Breast cancer anti-estrogen resistance protei... 42.0 0.019
sp|P72780|HHOA_SYNY3 Putative serine protease HhoA OS=Synechocyst... 41.6 0.020
sp|Q8YCG3|FBPC_BRUME Fe(3+) ions import ATP-binding protein FbpC ... 41.6 0.020
sp|Q9PW72|PDLI4_CHICK PDZ and LIM domain protein 4 OS=Gallus gall... 41.6 0.020
sp|P59047|NALP5_HUMAN NACHT, LRR and PYD domains-containing prote... 42.0 0.020
sp|B3P3J9|HTRA2_DROER Serine protease HTRA2, mitochondrial OS=Dro... 41.6 0.021
sp|Q7TSG5|SH321_MOUSE SH3 domain-containing protein 21 OS=Mus mus... 42.0 0.021
sp|Q4A6Z8|KTHY_MYCS5 Thymidylate kinase OS=Mycoplasmopsis synovia... 40.4 0.022
sp|P08631|HCK_HUMAN Tyrosine-protein kinase HCK OS=Homo sapiens O... 41.6 0.022
sp|A1SWH9|UGPC_PSYIN sn-glycerol-3-phosphate import ATP-binding p... 41.6 0.022
sp|D1ZRK4|SHO1_SORMK High osmolarity signaling protein SHO1 OS=So... 41.2 0.022
sp|Q2P2T5|DER_XANOM GTPase Der OS=Xanthomonas oryzae pv. oryzae (... 41.6 0.023
sp|Q99962|SH3G2_HUMAN Endophilin-A1 OS=Homo sapiens OX=9606 GN=SH... 41.2 0.024
sp|Q8TEC5|SH3R2_HUMAN E3 ubiquitin-protein ligase SH3RF2 OS=Homo ... 41.6 0.024
sp|Q9Z3I3|NODI_BRASS Nod factor export ATP-binding protein I OS=B... 41.2 0.024
sp|Q4WUG9|SHO1_ASPFU High osmolarity signaling protein sho1 OS=As... 40.8 0.025
sp|B0Y3Z4|SHO1_ASPFC High osmolarity signaling protein sho1 OS=As... 40.8 0.025
sp|Q95KR7|LCK_SAISC Proto-oncogene tyrosine-protein kinase LCK OS... 41.6 0.025
sp|Q8IXQ8|PDZD9_HUMAN PDZ domain-containing protein 9 OS=Homo sap... 40.8 0.026
sp|Q06449|PIN3_YEAST [PSI+] inducibility protein 3 OS=Saccharomyc... 40.4 0.026
sp|Q9FI14|TAO1_ARATH Disease resistance protein TAO1 OS=Arabidops... 41.6 0.026
sp|P42683|LCK_CHICK Proto-oncogene tyrosine-protein kinase LCK OS... 41.6 0.026
sp|Q55669|CTPA_SYNY3 Carboxyl-terminal-processing protease OS=Syn... 41.2 0.026
sp|Q8U4K7|PGK2_PYRFU 2-phosphoglycerate kinase OS=Pyrococcus furi... 40.8 0.026
sp|O35180|SH3G3_RAT Endophilin-A3 OS=Rattus norvegicus OX=10116 G... 41.2 0.027
sp|B4PST0|HTRA2_DROYA Serine protease HTRA2, mitochondrial OS=Dro... 41.2 0.027
sp|P40341|YTA12_YEAST Mitochondrial respiratory chain complexes a... 41.6 0.028
sp|P43603|LSB3_YEAST LAS seventeen-binding protein 3 OS=Saccharom... 41.2 0.028
sp|A7A261|LSB3_YEAS7 LAS seventeen-binding protein 3 OS=Saccharom... 41.2 0.028
sp|P19706|MYSB_ACACA Myosin heavy chain IB OS=Acanthamoeba castel... 41.6 0.028
sp|O14136|PEX13_SCHPO Peroxisomal membrane protein pex13 OS=Schiz... 40.8 0.028
sp|Q62421|SH3G3_MOUSE Endophilin-A3 OS=Mus musculus OX=10090 GN=S... 40.8 0.029
sp|P42687|SPK1_GIRTI Tyrosine-protein kinase SPK-1 OS=Girardia ti... 41.2 0.029
sp|A6VUA4|DEGPL_MARMS Probable periplasmic serine endoprotease De... 41.2 0.030
sp|Q3U214|MAST3_MOUSE Microtubule-associated serine/threonine-pro... 41.6 0.031
sp|A6ZKU1|SLA1_YEAS7 Actin cytoskeleton-regulatory complex protei... 41.6 0.031
sp|P43069|CDC25_CANAL Cell division control protein 25 OS=Candida... 41.6 0.032
sp|P32790|SLA1_YEAST Actin cytoskeleton-regulatory complex protei... 41.6 0.032
sp|Q9Z762|DER_CHLPN GTPase Der OS=Chlamydia pneumoniae OX=83558 G... 41.2 0.032
sp|Q8TF65|GIPC2_HUMAN PDZ domain-containing protein GIPC2 OS=Homo... 40.8 0.033
sp|P37530|DGK_BACSU Deoxyguanosine kinase OS=Bacillus subtilis (s... 40.0 0.033
sp|Q5PXS1|LCK_AOTNA Tyrosine-protein kinase Lck OS=Aotus nancymaa... 41.2 0.034
>sp|Q5RDQ2|PALS1_PONAB Protein PALS1 OS=Pongo abelii OX=9601 GN=PALS1
PE=2 SV=1
Length=675
Score = 919 bits (2376), Expect = 0.0, Method: Composition-based stats.
Identities = 672/675 (99%), Positives = 674/675 (99%), Gaps = 0/675 (0%)
Query 1 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR 60
MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR
Sbjct 1 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR 60
Query 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK 120
QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK
Sbjct 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK 120
Query 121 ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF 180
ILEIEDLFSSLKHIQHTL+DSQSQEDISLLLQLVQNK FQNAFKIHNAITVHMNKASPPF
Sbjct 121 ILEIEDLFSSLKHIQHTLIDSQSQEDISLLLQLVQNKGFQNAFKIHNAITVHMNKASPPF 180
Query 181 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE 240
PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE
Sbjct 181 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE 240
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE
Sbjct 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
VLEINGIEIRGKDVNEVFDLL+DMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD
Sbjct 301 VLEINGIEIRGKDVNEVFDLLADMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
Query 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK
Sbjct 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
Query 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR
Sbjct 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI
Sbjct 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP
Sbjct 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN
Sbjct 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
Query 661 KLDTEPQWVPSTWLR 675
KLDTEPQWVPSTWLR
Sbjct 661 KLDTEPQWVPSTWLR 675
>sp|Q8N3R9|PALS1_HUMAN Protein PALS1 OS=Homo sapiens OX=9606 GN=PALS1
PE=1 SV=3
Length=675
Score = 919 bits (2375), Expect = 0.0, Method: Composition-based stats.
Identities = 675/675 (100%), Positives = 675/675 (100%), Gaps = 0/675 (0%)
Query 1 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR 60
MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR
Sbjct 1 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR 60
Query 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK 120
QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK
Sbjct 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK 120
Query 121 ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF 180
ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF
Sbjct 121 ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF 180
Query 181 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE 240
PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE
Sbjct 181 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE 240
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE
Sbjct 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD
Sbjct 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
Query 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK
Sbjct 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
Query 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR
Sbjct 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI
Sbjct 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP
Sbjct 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN
Sbjct 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
Query 661 KLDTEPQWVPSTWLR 675
KLDTEPQWVPSTWLR
Sbjct 661 KLDTEPQWVPSTWLR 675
>sp|E2QY99|PALS1_CANLF Protein PALS1 OS=Canis lupus familiaris
OX=9615 GN=PALS1 PE=1 SV=1
Length=675
Score = 915 bits (2365), Expect = 0.0, Method: Composition-based stats.
Identities = 663/675 (98%), Positives = 672/675 (99%), Gaps = 0/675 (0%)
Query 1 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR 60
MTTSHMNGHVTEESD+EVKNVDLASPEEHQKHREMAVDCPGDLGTRMMP+RRSAQLERIR
Sbjct 1 MTTSHMNGHVTEESDNEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPVRRSAQLERIR 60
Query 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK 120
QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNP+FDTEEGIVLESPHYAVK
Sbjct 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPIFDTEEGIVLESPHYAVK 120
Query 121 ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF 180
ILE+EDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNA+TVHMNKASPPF
Sbjct 121 ILEVEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAVTVHMNKASPPF 180
Query 181 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE 240
PLISNAQDLAQEVQTVLKPVHHKEGQELTALL+ PH+QALLLAHDKVAEQEMQLEP TDE
Sbjct 181 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLSAPHVQALLLAHDKVAEQEMQLEPFTDE 240
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE
Sbjct 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD
Sbjct 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
Query 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
DPYVPCRELGLSFQKGDILH+ISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK
Sbjct 361 DPYVPCRELGLSFQKGDILHIISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
Query 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR
Sbjct 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRD EVAGRDYHFVSRQAFEADI
Sbjct 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDHEVAGRDYHFVSRQAFEADI 540
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP
Sbjct 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN
Sbjct 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
Query 661 KLDTEPQWVPSTWLR 675
KLDTEPQWVPS+WLR
Sbjct 661 KLDTEPQWVPSSWLR 675
>sp|B4F7E7|PALS1_RAT Protein PALS1 OS=Rattus norvegicus OX=10116
GN=Pals1 PE=1 SV=1
Length=675
Score = 895 bits (2314), Expect = 0.0, Method: Composition-based stats.
Identities = 654/675 (97%), Positives = 665/675 (99%), Gaps = 0/675 (0%)
Query 1 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR 60
MTTS+MNGHVTEESDS +KN+ LASPEEH KHREMAVDCPGDLGTR+MP+RRSAQLERIR
Sbjct 1 MTTSYMNGHVTEESDSGIKNLGLASPEEHPKHREMAVDCPGDLGTRLMPVRRSAQLERIR 60
Query 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK 120
QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNP+FDTEEGIVLESPHYAVK
Sbjct 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPIFDTEEGIVLESPHYAVK 120
Query 121 ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF 180
ILE+EDLFSSLKHIQHTLVDSQSQEDISLLLQLVQN+DFQNAFKIHNA+TVHMNKASPPF
Sbjct 121 ILEVEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNRDFQNAFKIHNAVTVHMNKASPPF 180
Query 181 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE 240
PLI+N QDL QEVQTVLKPVH KEGQELTALLN PHIQALLLAHDKVAEQEMQLEPITDE
Sbjct 181 PLIANVQDLVQEVQTVLKPVHQKEGQELTALLNAPHIQALLLAHDKVAEQEMQLEPITDE 240
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
RVYESIG YGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE
Sbjct 241 RVYESIGHYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD
Sbjct 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
Query 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK
Sbjct 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
Query 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR
Sbjct 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTR+RRD EVAGRDYHFVSRQAFEADI
Sbjct 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRNRRDHEVAGRDYHFVSRQAFEADI 540
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR QSLKTLRNSDLKPYIIFIAPP
Sbjct 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRAQSLKTLRNSDLKPYIIFIAPP 600
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN
Sbjct 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
Query 661 KLDTEPQWVPSTWLR 675
KLDTEPQWVPSTWLR
Sbjct 661 KLDTEPQWVPSTWLR 675
>sp|Q9JLB2|PALS1_MOUSE Protein PALS1 OS=Mus musculus OX=10090
GN=Pals1 PE=1 SV=1
Length=675
Score = 895 bits (2314), Expect = 0.0, Method: Composition-based stats.
Identities = 653/675 (97%), Positives = 666/675 (99%), Gaps = 0/675 (0%)
Query 1 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR 60
MTTS+MNGHVTEESDS +KN+DLASPEE+ KHREMAVDCPGDLGTRMMP+RRSAQLERIR
Sbjct 1 MTTSYMNGHVTEESDSGIKNLDLASPEEYPKHREMAVDCPGDLGTRMMPVRRSAQLERIR 60
Query 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESPHYAVK 120
QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNP+FDTEEGIVLESPHYAV
Sbjct 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPIFDTEEGIVLESPHYAVN 120
Query 121 ILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPF 180
IL++EDLFSSLKHIQHTLVDSQSQEDISLLLQLVQN+DFQNAFKIHNA+TVHM+KASPPF
Sbjct 121 ILDVEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNRDFQNAFKIHNAVTVHMSKASPPF 180
Query 181 PLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE 240
PLI+N QDL QEVQTVLKPVH KEGQELTALLN PHIQALLLAHDKVAEQEMQLEPITDE
Sbjct 181 PLIANVQDLVQEVQTVLKPVHQKEGQELTALLNAPHIQALLLAHDKVAEQEMQLEPITDE 240
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
RVYESIG YGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE
Sbjct 241 RVYESIGHYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD
Sbjct 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
Query 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK
Sbjct 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
Query 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR
Sbjct 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTR+RRD EVAGRDYHFVSRQAFEADI
Sbjct 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRNRRDHEVAGRDYHFVSRQAFEADI 540
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP
Sbjct 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN
Sbjct 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
Query 661 KLDTEPQWVPSTWLR 675
KLDTEPQWVPSTWLR
Sbjct 661 KLDTEPQWVPSTWLR 675
>sp|Q8JHF4|PAL1A_DANRE Protein PALS1 OS=Danio rerio OX=7955 GN=pals1a
PE=1 SV=2
Length=677
Score = 810 bits (2092), Expect = 0.0, Method: Composition-based stats.
Identities = 517/681 (76%), Positives = 581/681 (85%), Gaps = 10/681 (1%)
Query 1 MTTSHMNGHVTEESDSEVKNVDLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIR 60
MTTSHMNG+VTE D+ E Q+HREMAVDCP +LG R +P+RRSAQLE+IR
Sbjct 1 MTTSHMNGYVTESDGG--GGTDIVE-EGVQRHREMAVDCPSELGARTLPVRRSAQLEKIR 57
Query 61 QQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIV-----LESP 115
QQQED RRR EE +QELDLNSSMRLKKL+Q PK GIDNP F+ EG L+S
Sbjct 58 QQQEDRRRREEEGRSRQELDLNSSMRLKKLSQ-NPKVGIDNPTFEQMEGPGGSAGGLQSL 116
Query 116 HYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNK 175
+LE+EDL SLK +QH+L DSQSQED+ L+LQLVQ DFQ AF IHN++ +MN+
Sbjct 117 IAPPALLELEDLLMSLKQVQHSLNDSQSQEDVELVLQLVQKPDFQKAFSIHNSVAHYMNR 176
Query 176 ASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLE 235
SPP+PL +AQ LAQEV+ +++ HKEG EL++LL+T H+QAL++AHD VAEQEMQLE
Sbjct 177 PSPPYPLTDHAQTLAQEVEVMVQNSSHKEGLELSSLLSTSHMQALMMAHDSVAEQEMQLE 236
Query 236 PITDE-RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGL 294
P+ E++ Q+GGETVKIVRIEKA+DIPLGATVRN+MDSV+ISRIVKGGAAE+SGL
Sbjct 237 PLVPSVNASETLTQWGGETVKIVRIEKAKDIPLGATVRNDMDSVVISRIVKGGAAERSGL 296
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHF 354
LHEGDE+LEING+EIRGKDVNEVFD+L+DMHG L+FVLIPS QIK PP KETV+HVKAHF
Sbjct 297 LHEGDEILEINGVEIRGKDVNEVFDILADMHGVLSFVLIPSAQIKSPPIKETVVHVKAHF 356
Query 355 DYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ 414
DYDPSDDPYVPCRELGL FQKGDILH+ISQ+DPNWWQAYR+GDEDNQPLAGLVPGKSFQQ
Sbjct 357 DYDPSDDPYVPCRELGLCFQKGDILHIISQDDPNWWQAYRDGDEDNQPLAGLVPGKSFQQ 416
Query 415 QREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQ 474
QREAMKQTIEEDKEPEK+GKLWCAKK KKKRKK+ YNANKNDD+DNEEILTYEEM+LYHQ
Sbjct 417 QREAMKQTIEEDKEPEKTGKLWCAKKTKKKRKKMQYNANKNDDFDNEEILTYEEMALYHQ 476
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
PANRKRPI LIGP NCGQNELRQRL++ E DRFA VPHTTRSRRD E GRDYHFVSRQ
Sbjct 477 PANRKRPIALIGPPNCGQNELRQRLLSTEPDRFAGPVPHTTRSRRDAEANGRDYHFVSRQ 536
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
AFE D AAGKFIE GEFEKN YGTS DSVRQVIN+GKICLL + TQSLK LR+SDLKPYI
Sbjct 537 AFEMDSAAGKFIESGEFEKNFYGTSTDSVRQVINTGKICLLCVHTQSLKVLRSSDLKPYI 596
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFIAPPSQERLRALLAK+ KNPKPEELR+IIEK REMEQN GH FD AIVN+DLDK+YQE
Sbjct 597 IFIAPPSQERLRALLAKDNKNPKPEELRDIIEKAREMEQNYGHLFDAAIVNTDLDKSYQE 656
Query 655 LLRLINKLDTEPQWVPSTWLR 675
LLRLINKLDTEPQWVPS+WLR
Sbjct 657 LLRLINKLDTEPQWVPSSWLR 677
>sp|Q24210|CSKP_DROME Peripheral plasma membrane protein CASK
OS=Drosophila melanogaster OX=7227 GN=CASK PE=1 SV=4
Length=898
Score = 598 bits (1542), Expect = 0.0, Method: Composition-based stats.
Identities = 201/652 (31%), Positives = 339/652 (52%), Gaps = 59/652 (9%)
Query 50 IRRSAQLER--IRQQQEDMRR---RREEEGKKQELDLNSSMR-LKKLAQIPPKTGIDNPM 103
IR +L+R + E+++R RR+ +G Q + ++M L P TG +
Sbjct 278 IRDRDKLQRTHLADTVEELKRYNARRKLKGAVQAIAGGTNMDPLYATDADMPITGATDEW 337
Query 104 FDTEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAF 163
D E GI + I D + +Q VD+ D +L+ + F F
Sbjct 338 ADEEAGIE--------AVQRILDCLDDIYSLQDAHVDADVLRD---MLRDNRLHQFLQLF 386
Query 164 KIHNAITVHMNKASPPFPLISNAQDLAQEVQTV-----LKPVHHKEGQELTALLNTPHIQ 218
A V N +P + +D+ +++ + L + KE EL LL PH+Q
Sbjct 387 DRIAATVVTSNGRAPAAEAVGRCRDVLEQLSSTSGGNSLGGKYAKE--ELMRLLAAPHMQ 444
Query 219 ALLLAHDKVA-----EQEMQLEPIT---DERVYESIGQYGGE-----TVKIVRIEKARDI 265
ALL +HD VA E+ +++ P E GGE V++V+ +K D
Sbjct 445 ALLHSHDVVARDVYGEEALRVTPPPMVPYLNGDELDNVEGGELQHVTRVRLVQFQKNTDE 504
Query 266 PLGATVRNEMDS-VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
P+G T++ D I++RI+ GG + LH GDE+ EING ++ + V ++ +L +
Sbjct 505 PMGITLKMTEDGRCIVARIMHGGMIHRQATLHVGDEIREINGQPVQHQSVGQLQRMLREA 564
Query 325 HGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ 384
G++TF ++PS + PPP + I V+A FDY+P DD +PC + G+SFQ GDIL +IS+
Sbjct 565 RGSVTFKIVPSYRSAPPPCE---IFVRAQFDYNPLDDELIPCAQAGISFQVGDILQIISK 621
Query 385 EDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKK 444
+D +WWQA + + AGL+P Q+ R A + T+++ K+ + + ++ K KK
Sbjct 622 DDHHWWQARLDTVGGS---AGLIPSPELQEWRIACQ-TVDKTKQEQVNCSIFGRK---KK 674
Query 445 RKKVLYNANKNDDYDNEEILTYEEMS--LYHQPANRKRPIILIGPQNCGQNELRQRLMNK 502
+ + Y A N +D +++TYEE+ P +++ ++L+G G+ ++ L++K
Sbjct 675 QCRDKYLAKHNAIFDTLDVVTYEEVVKVPVGDPNFQRKTLVLLGAHGVGRRHIKNTLISK 734
Query 503 EKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDS 562
D++A +PHTTR + +E GR Y+FVS ADI A +++E+G E +YGT +D+
Sbjct 735 YPDKYAYPIPHTTRPAKPEEENGRSYYFVSHDEMMADIGANEYLEYGTHEDAMYGTKLDT 794
Query 563 VRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELR 622
+R++ GK+ +L + Q+LK LR ++ PY++FIA PS + + L
Sbjct 795 IRRIHTEGKMAILDVEPQALKILRTAEFTPYVVFIAAPSLQNIADY---------DGSLE 845
Query 623 EIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
+ +++ + Q GH+FD IVN+D+ + L I+++ T PQWVP +WL
Sbjct 846 RLAKESEMLRQLYGHFFDLTIVNNDISETIATLETAIDRVHTTPQWVPVSWL 897
>sp|Q8BVD5|MPP7_MOUSE MAGUK p55 subfamily member 7 OS=Mus musculus
OX=10090 GN=Mpp7 PE=1 SV=2
Length=576
Score = 593 bits (1530), Expect = 0.0, Method: Composition-based stats.
Identities = 222/576 (39%), Positives = 338/576 (59%), Gaps = 40/576 (7%)
Query 124 IEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLI 183
+ +L ++L VD SQED++ L + K + KIH + H + P P++
Sbjct 14 LYELLAALPAQLQPHVD--SQEDLTFLWDVFGEKSLHSLVKIHEKL--HCYEKQNPLPIL 69
Query 184 SNAQDLAQEVQTVLKPV-HHKEGQELTALLNTPHIQALLLAHDKVAEQEMQ--LEPITDE 240
A LA ++ L+ + E +EL LL+ P+++ALL HD VA++ L P+ D+
Sbjct 70 HGAAALADDLTEELQNKLPNSEIRELLKLLSKPNVKALLSVHDTVAQKSYDPVLPPVPDD 129
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNE--MDSVIISRIVKGGAAEKSGLLHEG 298
E ++VKI+R+ K + PLGAT++ + ++ ++RI++GGAA++SGL+H G
Sbjct 130 IDDEE------DSVKIIRLVKNSE-PLGATIKKDEQTGAITVARIMRGGAADRSGLIHVG 182
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDP 358
DE+ E+NGI + K E+ +LS G +TF +IPS + + P+KE I +KA FDYDP
Sbjct 183 DELREVNGIPVEDKRPEEIIKILSQSKGAITFKIIPSTK-EETPSKEGKIFIKALFDYDP 241
Query 359 SDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREA 418
+D +PC+E GLSF+KGDIL ++SQ+D WWQA EGD + P AGL+P K FQ++R A
Sbjct 242 KEDKAIPCKEAGLSFRKGDILQIMSQDDVTWWQAKHEGDAN--PRAGLIPSKHFQERRLA 299
Query 419 MKQT--------IEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMS 470
+++ + K ++KN KK K +Y K++ YD ++ TYEE++
Sbjct 300 LRRPEIVVQPLKLSNTKSSGFRRSFRLSRKN-KKINKSMYECKKSEQYDTADVPTYEEVT 358
Query 471 LYH-QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYH 529
Y Q ++ R I+L+GP G NEL+++L+ + + VPHTTR+RR QE G +Y
Sbjct 359 PYRRQIHDKYRLIVLVGPVGVGLNELKRKLLMSDAQHYGVIVPHTTRARRSQESDGVEYI 418
Query 530 FVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD 589
F+S+ FE D+ KFIE+GE++ N YGTSIDSVR V+ K+CLL ++ ++K LR +
Sbjct 419 FISKHLFETDVQINKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLE 478
Query 590 LKPYIIFIAPPSQERLRALLAK----EGKNP-------KPEELREIIEKTREMEQNNGHY 638
KPY+IFI PPS ERLR ++ E+ +E+I+ + ME GH
Sbjct 479 FKPYVIFIKPPSIERLRETRKNAKIISSRDDQGTAKPFTEEDFQEMIKSAQIMESQYGHL 538
Query 639 FDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
FD I+N DL A+ EL +KL+T+ WVP +WL
Sbjct 539 FDKIIINDDLTVAFNELKTTFDKLETDTHWVPVSWL 574
>sp|A8KBF6|MPP7_XENTR MAGUK p55 subfamily member 7 OS=Xenopus
tropicalis OX=8364 GN=mpp7 PE=2 SV=1
Length=576
Score = 573 bits (1477), Expect = 0.0, Method: Composition-based stats.
Identities = 222/575 (39%), Positives = 340/575 (59%), Gaps = 38/575 (7%)
Query 124 IEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLI 183
+ ++ ++L VD SQED++ L + K + KIH + H + P P+I
Sbjct 14 LYEILATLPAQLQPHVD--SQEDLTFLWDMFGEKSLHSLVKIHEKL--HYYEKENPMPVI 69
Query 184 SNAQDLAQEVQTVLKPVH-HKEGQELTALLNTPHIQALLLAHDKVAEQEMQ--LEPITDE 240
+A LA+E+ L+ + E +EL LL+ P+++ALL HD VA++ L P+
Sbjct 70 HSATALAEELAEELQSKSLNSEIRELLKLLSKPNLKALLSVHDTVAQKSYDPVLPPMP-- 127
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNE--MDSVIISRIVKGGAAEKSGLLHEG 298
++VKI+R+ K R+ PLGAT++ + +++++RI++GGAA++SGL+H G
Sbjct 128 ----DDIDDDEDSVKIIRLVKNRE-PLGATIKKDEKTGAIVVARIMRGGAADRSGLIHVG 182
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDP 358
DE+ E+NGI + K E+ +L+ G +TF +IPS + + PP + + VKA FDY P
Sbjct 183 DELREVNGISVEDKKPEEIIHILAQSQGAITFKIIPSIK-EEPPNNDGKMFVKALFDYYP 241
Query 359 SDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREA 418
++D +PC+E GLSF+KGDIL ++SQ+D WWQA EGD + P AGL+P K FQ++R A
Sbjct 242 NEDKAIPCKEAGLSFRKGDILQIMSQDDATWWQAKHEGDAN--PRAGLIPSKQFQERRFA 299
Query 419 MKQTIEED---KEPEKSG----KLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSL 471
+++ + + K P + + + + +K K +Y K+D YD ++ TYEE++L
Sbjct 300 LRKPVVSNQPQKVPNRKSSGFRRSFRLSRKDRKTNKFMYECKKSDQYDTADVPTYEEVAL 359
Query 472 YHQPAN-RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
Y + N + R +IL+GP G NEL+++++ + VPHTTR +R QE G +Y F
Sbjct 360 YQRKPNEKYRLVILVGPVGVGVNELKRKVLIGNSQHYGVTVPHTTRGKRSQENDGVEYIF 419
Query 531 VSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL 590
+S+ FE DI KFIE+GE++ N YGTS+DSVR V+ KICLL ++ SLK LR S+
Sbjct 420 ISKHLFETDIHNNKFIEYGEYKNNYYGTSLDSVRSVLAKNKICLLDVQPNSLKHLRTSEF 479
Query 591 KPYIIFIAPPSQERLRALLAK----EGKNPK-------PEELREIIEKTREMEQNNGHYF 639
KP++IFI PP+ ERLR GK+ + E+ E+I+ ME H+F
Sbjct 480 KPFVIFIKPPTIERLRETRRNAKVISGKDERGAAKPFSDEDFEEMIQSAEAMEAQYDHFF 539
Query 640 DTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
DT IVN DL AY EL + +L+ E WVP +WL
Sbjct 540 DTTIVNDDLSAAYNELRSTLERLEMEGFWVPVSWL 574
>sp|Q6P0D7|MPP7_DANRE MAGUK p55 subfamily member 7 OS=Danio rerio
OX=7955 GN=mpp7 PE=1 SV=1
Length=576
Score = 567 bits (1461), Expect = 0.0, Method: Composition-based stats.
Identities = 214/574 (37%), Positives = 336/574 (59%), Gaps = 38/574 (7%)
Query 124 IEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLI 183
+ +L S L V +S +D S L + + + KIH + + + A P P++
Sbjct 14 LYELLSVLPSQLQPHV--ESPDDRSFLHAMFGERSLHSLVKIHEKLQCYEDCA--PTPVL 69
Query 184 SNAQDLAQEVQTVLKP-VHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQ--LEPITDE 240
+A LA ++ L+ E +EL LL+ PH+++LL HD VA++ L P+ D+
Sbjct 70 DSAGSLAADLTEELQARSASNEIRELVKLLSKPHVKSLLSVHDTVAKKSYDPELPPLPDD 129
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD--SVIISRIVKGGAAEKSGLLHEG 298
E ++VKI+R+ K ++ PLGAT++ + +++++RI++GGAA++SGL+H G
Sbjct 130 IDDEE------DSVKIIRLVKNKE-PLGATIKKDEHTGAILVARILRGGAADRSGLIHVG 182
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDP 358
DE+ E+NGI + K E+ +LS G +TF ++P + + +KE + +KA FDY+P
Sbjct 183 DELKEVNGIPVDDKKPEEIIRILSQSQGAITFKVVPGIKDEAQ-SKEPKMFIKALFDYNP 241
Query 359 SDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREA 418
++D +PC+E GL F+KGDIL V+SQ+D WWQA EGD + AGL+P K FQ++R A
Sbjct 242 AEDKAIPCKEAGLGFKKGDILQVMSQDDATWWQAKLEGDGNL--RAGLIPSKHFQERRLA 299
Query 419 MKQTIEEDKEPEKSGKLWCAKKNK-------KKRKKVLYNANKNDDYDNEEILTYEEMSL 471
+ + S K + + KK K +Y K++ YD ++ TYEE++
Sbjct 300 VWRPTPVMTLQRTSSKRFSGLRRSFRLSRRDKKTNKSMYECKKSEQYDTADVPTYEEVTT 359
Query 472 YHQP-ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
Y + +R R ++L+GP G NEL+++L+ + F+ +PHT+RS+R QE G +YHF
Sbjct 360 YRRKHGDRHRLVVLVGPTGVGLNELKRKLLISDTQHFSVTIPHTSRSKRHQESEGVEYHF 419
Query 531 VSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL 590
+S+ FEADI KFIEHGE++ N YGTS DSVR V++ K+CLL ++ +LK LR ++
Sbjct 420 ISKNLFEADIQNNKFIEHGEYKGNYYGTSFDSVRSVLSKNKVCLLDVQPHTLKHLRTAEF 479
Query 591 KPYIIFIAPPSQERLRALLAK----EGKNPK-------PEELREIIEKTREMEQNNGHYF 639
KPY++F+ PP ERLR GK+ K E+ E+I ++ ME GH F
Sbjct 480 KPYVVFVKPPCIERLRETRRNAKVISGKDDKTSSKAFSEEDFLEMISASQMMENQYGHLF 539
Query 640 DTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTW 673
+ IVN DL A+ EL + + K++TE WVP +W
Sbjct 540 EKVIVNDDLTVAFSELKQALKKVETEAHWVPISW 573
>sp|Q5U2Y3|MPP7_RAT MAGUK p55 subfamily member 7 OS=Rattus norvegicus
OX=10116 GN=Mpp7 PE=2 SV=2
Length=576
Score = 551 bits (1419), Expect = 0.0, Method: Composition-based stats.
Identities = 219/575 (38%), Positives = 339/575 (59%), Gaps = 38/575 (7%)
Query 124 IEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLI 183
+ +L ++L VD SQED++ L + K + KIH + H + P P++
Sbjct 14 LYELLAALPAQLQPHVD--SQEDLTFLWDMFGEKSLHSLVKIHEKL--HYYEKQSPVPIL 69
Query 184 SNAQDLAQEVQTVLKPVH-HKEGQELTALLNTPHIQALLLAHDKVAEQEMQ--LEPITDE 240
A LA ++ L+ + E +EL LL+ P+++ALL HD VA++ L P+ D+
Sbjct 70 HGAAALADDLADELQNKPPNSEIRELLKLLSKPNVKALLSVHDTVAQKSYDPVLPPMPDD 129
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNE--MDSVIISRIVKGGAAEKSGLLHEG 298
E ++VKI+R+ K R+ PLGAT++ + ++ ++RI++GGAA++SGL+H G
Sbjct 130 IDDEE------DSVKIIRLVKNRE-PLGATIKKDEQTGAITVARIMRGGAADRSGLIHVG 182
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDP 358
DE+ E+NGI + K E+ +LS G +TF +IPS + + P+KE I +KA FDYDP
Sbjct 183 DELREVNGIPVEDKRPEEIIQILSQSQGAITFKIIPSTK-EEIPSKEGKIFIKALFDYDP 241
Query 359 SDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREA 418
+D +PC+E GLSF+KGDIL ++SQ+D WWQA EGD + P AGL+P K FQ++R A
Sbjct 242 KEDKAIPCKEAGLSFRKGDILQIMSQDDATWWQAKHEGDTN--PRAGLIPSKHFQERRLA 299
Query 419 MKQT-------IEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSL 471
+++ +++ + + + KK K +Y K++ YD ++ TYEE++
Sbjct 300 LRRPEIVVQPLKLSNRKSSGFRRSFRLSRKDKKTNKSMYECKKSEQYDTADVPTYEEVTP 359
Query 472 YH-QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
Y Q ++ R ++L+GP G NEL+++L+ + + VPHTTR+RR QE G +Y F
Sbjct 360 YRRQTHDKYRLVVLVGPVGVGLNELKRKLLMSDTQHYGVTVPHTTRARRSQESDGVEYIF 419
Query 531 VSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL 590
+S+ FE D+ KFIE+GE++ N YGTSIDSVR V+ K+CLL ++ ++K LR +
Sbjct 420 ISKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEF 479
Query 591 KPYIIFIAPPSQERLRALLAK----EGKNP-------KPEELREIIEKTREMEQNNGHYF 639
KPY+IFI PPS ERLR ++ E+ +E+I+ + ME GH F
Sbjct 480 KPYVIFIKPPSIERLRETRKNAKIISSRDDQGTAKPFTEEDFQEMIKSAQIMESQYGHLF 539
Query 640 DTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
D I+N DL A+ EL +KL+T+ WVP +WL
Sbjct 540 DKIIINDDLTVAFNELKTTFDKLETDAHWVPVSWL 574
>sp|Q5T2T1|MPP7_HUMAN MAGUK p55 subfamily member 7 OS=Homo sapiens
OX=9606 GN=MPP7 PE=1 SV=1
Length=576
Score = 551 bits (1419), Expect = 0.0, Method: Composition-based stats.
Identities = 217/575 (38%), Positives = 339/575 (59%), Gaps = 38/575 (7%)
Query 124 IEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLI 183
+ +L ++L VD SQED++ L + K + KIH + H + P P++
Sbjct 14 LYELLAALPAQLQPHVD--SQEDLTFLWDMFGEKSLHSLVKIHEKL--HYYEKQSPVPIL 69
Query 184 SNAQDLAQEVQTVLKPVH-HKEGQELTALLNTPHIQALLLAHDKVAEQEMQ--LEPITDE 240
A LA ++ L+ + E +EL LL+ P+++ALL HD VA++ L P+ ++
Sbjct 70 HGAAALADDLAEELQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYDPVLPPMPED 129
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNE--MDSVIISRIVKGGAAEKSGLLHEG 298
E ++VKI+R+ K R+ PLGAT++ + ++I++RI++GGAA++SGL+H G
Sbjct 130 IDDEE------DSVKIIRLVKNRE-PLGATIKKDEQTGAIIVARIMRGGAADRSGLIHVG 182
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDP 358
DE+ E+NGI + K E+ +L+ G +TF +IP + + P+KE + +KA FDY+P
Sbjct 183 DELREVNGIPVEDKRPEEIIQILAQSQGAITFKIIPGSK-EETPSKEGKMFIKALFDYNP 241
Query 359 SDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREA 418
++D +PC+E GLSF+KGDIL ++SQ+D WWQA E D + P AGL+P K FQ++R A
Sbjct 242 NEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKHEADAN--PRAGLIPSKHFQERRLA 299
Query 419 MKQT-------IEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSL 471
+++ +++ K + + KK K +Y K+D YD ++ TYEE++
Sbjct 300 LRRPEILVQPLKVSNRKSSGFRKSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTP 359
Query 472 YHQPAN-RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
Y + N + R ++L+GP G NEL+++L+ + + VPHTTR+RR QE G +Y F
Sbjct 360 YRRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYGVTVPHTTRARRSQESDGVEYIF 419
Query 531 VSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL 590
+S+ FE D+ KFIE+GE++ N YGTSIDSVR V+ K+CLL ++ ++K LR +
Sbjct 420 ISKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEF 479
Query 591 KPYIIFIAPPSQERLRALLAK----EGKNP-------KPEELREIIEKTREMEQNNGHYF 639
KPY+IFI PPS ERLR ++ E+ +E+I+ + ME GH F
Sbjct 480 KPYVIFIKPPSIERLRETRKNAKIISSRDDQGAAKPFTEEDFQEMIKSAQIMESQYGHLF 539
Query 640 DTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
D I+N DL A+ EL +KL+TE WVP +WL
Sbjct 540 DKIIINDDLTVAFNELKTTFDKLETETHWVPVSWL 574
>sp|A6QQZ7|MPP7_BOVIN MAGUK p55 subfamily member 7 OS=Bos taurus
OX=9913 GN=MPP7 PE=2 SV=1
Length=576
Score = 547 bits (1410), Expect = 0.0, Method: Composition-based stats.
Identities = 216/575 (38%), Positives = 338/575 (59%), Gaps = 38/575 (7%)
Query 124 IEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLI 183
+ +L +L VD SQED++ L + K + KIH + H + P P++
Sbjct 14 LYELLVALPAQLQPHVD--SQEDLTFLWDVFGEKSLHSLVKIHEKL--HYYEKQNPVPIL 69
Query 184 SNAQDLAQEVQTVLKPVH-HKEGQELTALLNTPHIQALLLAHDKVAEQEMQ--LEPITDE 240
A LA ++ L+ + E +EL LL+ P+++ALL HD VA++ L P+ D+
Sbjct 70 QGAAALADDLAEELQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYDPVLPPMPDD 129
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNE--MDSVIISRIVKGGAAEKSGLLHEG 298
E ++VKI+R+ K R+ PLGAT++ + +++++RI++GGAA++SGL+H G
Sbjct 130 IDNEE------DSVKIIRLVKNRE-PLGATIKKDEQTGAIVVARIMRGGAADRSGLIHVG 182
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDP 358
DE+ E+NGI + K E+ +L+ G +TF +IPS + + P+KE + +KA FDYDP
Sbjct 183 DELREVNGIPVEDKRPEEIIQILAQSQGAITFKIIPSIK-EETPSKEGKMFIKALFDYDP 241
Query 359 SDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREA 418
++D +PC+E GLSF+KGDIL ++SQ+D WWQA EGD + P AGL+P K FQ++R A
Sbjct 242 NEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKHEGDAN--PRAGLIPSKHFQERRLA 299
Query 419 MKQT-------IEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSL 471
+++ ++ + + + KK K +Y ++D YD ++ TYEE++
Sbjct 300 LRRPEILVQPLKVSSRKSSGFRRSFRLSRKDKKTNKSMYECKRSDQYDTADVPTYEEVTP 359
Query 472 YHQPAN-RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
Y + N + R ++L+GP G NEL+++L+ + + VPHTTR RR QE G +Y F
Sbjct 360 YRRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYGVTVPHTTRPRRSQESDGVEYIF 419
Query 531 VSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL 590
+S+ FE D+ KFIE+GE++ N YGTSIDSVR V+ K+CLL ++ ++K LR +
Sbjct 420 ISKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEF 479
Query 591 KPYIIFIAPPSQERLRALLAK----EGKNP-------KPEELREIIEKTREMEQNNGHYF 639
KP++IFI PPS ERLR ++ ++ +E+I+ + ME GH F
Sbjct 480 KPFVIFIKPPSIERLRETRKNAKIISSRDDQGAAKPFTEDDFQEMIKSAQIMESQYGHLF 539
Query 640 DTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
D IVN DL A+ EL +KL+T+ WVP +WL
Sbjct 540 DKTIVNDDLAVAFNELKTTFDKLETDTHWVPVSWL 574
>sp|Q13368|MPP3_HUMAN MAGUK p55 subfamily member 3 OS=Homo sapiens
OX=9606 GN=MPP3 PE=1 SV=2
Length=585
Score = 533 bits (1372), Expect = 0.0, Method: Composition-based stats.
Identities = 199/572 (35%), Positives = 328/572 (57%), Gaps = 46/572 (8%)
Query 140 DSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKP 199
DS +E++ L + K KIH + + ++ P P++ +A LA++V L+
Sbjct 24 DSNHKEEMGFLRDVFSEKSLSYLMKIHEKLRYYERQS--PTPVLHSAVALAEDVMEELQA 81
Query 200 VH-HKEGQELTALLNTPHIQALLLAHDKVAEQEMQ--LEPITDERVYESIGQYGGETVKI 256
H + +EL LL+TPH++A+L+ HD VA++ L P+ D + + E+VKI
Sbjct 82 ASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDED----FDEESVKI 137
Query 257 VRIEKARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
VR+ K ++ PLGAT+R + S V+++RI++GGAA++SGL+H GDE+ E+NGI + K
Sbjct 138 VRLVKNKE-PLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRP 196
Query 315 NEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQ 374
+E+ +L+ G++T +IP+ Q + KE+ + ++A F Y+P +D +PC+E GL FQ
Sbjct 197 DEISQILAQSQGSITLKIIPATQ-EEDRLKESKVFMRALFHYNPREDRAIPCQEAGLPFQ 255
Query 375 KGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEK--- 431
+ +L V+SQ+DP WWQA R GD + AGL+P K FQ++R + ++ P+
Sbjct 256 RRQVLEVVSQDDPTWWQAKRVGDTNL--RAGLIPSKGFQERRLSYRRAAGTLPSPQSLRK 313
Query 432 -----------------------SGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEE 468
+G + ++R + ++ E+LTYEE
Sbjct 314 PPYDQPCDKETCDCEGYLKGHYVAGLRRSFRLGCRERLGGSQEGKMSSGAESPELLTYEE 373
Query 469 MSLY-HQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRD 527
++ Y HQP R R ++LIG +EL+Q+++ + F AVPHTTR R+ E G +
Sbjct 374 VARYQHQPGERPRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVE 433
Query 528 YHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN 587
YHFVS+QAFEAD+ KF+EHGE+++NLYGTS+++++ V+ K+CL+ + ++LK LR
Sbjct 434 YHFVSKQAFEADLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRT 493
Query 588 SDLKPYIIFIAPPSQERLRA----LLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAI 643
S+ KPYIIF+ P QE+ + ++ P E+ +E+ ++++ GH D +
Sbjct 494 SEFKPYIIFVKPAIQEKRKTPPMSPACEDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVL 553
Query 644 VNSDLDKAYQELLRLINKLDTEPQWVPSTWLR 675
V DL AY +L ++ KL + WVP +W+R
Sbjct 554 VKEDLQGAYSQLKVVLEKLSKDTHWVPVSWVR 585
>sp|O88954|MPP3_RAT MAGUK p55 subfamily member 3 OS=Rattus norvegicus
OX=10116 GN=Mpp3 PE=1 SV=3
Length=585
Score = 525 bits (1352), Expect = 3e-179, Method: Composition-based stats.
Identities = 199/572 (35%), Positives = 328/572 (57%), Gaps = 46/572 (8%)
Query 140 DSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKP 199
DS +E++ L + K KIH + + ++ P P++ +A LA++V L+
Sbjct 24 DSNHREEMGFLRDVFSEKSLGYLMKIHEKLRYYERQS--PTPVLHSAMALAEDVMEELQA 81
Query 200 VH-HKEGQELTALLNTPHIQALLLAHDKVAEQEMQ--LEPITDERVYESIGQYGGETVKI 256
H + +EL LL+TPH++A+L+ HD VA++ L P+ D + + E+VKI
Sbjct 82 ASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDED----FEEESVKI 137
Query 257 VRIEKARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
VR+ K ++ PLGAT+R + S V+++RI++GGAA++SGL+H GDE+ E+NGI + K
Sbjct 138 VRLVKNKE-PLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGITVLHKRP 196
Query 315 NEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQ 374
+E+ +L+ G++T +IP+ Q + KE+ + ++A F YDP +D +PC+E GL FQ
Sbjct 197 DEISQILAQSQGSITLKIIPATQ-EEDRFKESKVFMRALFHYDPREDRAIPCQEAGLPFQ 255
Query 375 KGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEK--- 431
+ +L V+SQ+DP WWQA R GD + AGL+P K FQ++R + ++T P+
Sbjct 256 QRQVLEVVSQDDPTWWQAKRVGDTNL--RAGLIPSKQFQERRLSYRRTTGTIPSPQNLRK 313
Query 432 -----------------------SGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEE 468
+G + ++R +++ +LTYEE
Sbjct 314 PLYDQPCDKETCDCDGYFKGHYVAGLRRSFRLGCRERLTGSQEVKVPVGAESQVLLTYEE 373
Query 469 MSLY-HQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRD 527
++ Y HQP R R ++LIG +EL+QR++ ++ F AVPHTTR R+ E G +
Sbjct 374 VARYQHQPGERSRLVVLIGSLGAHLHELKQRVVAEDPQHFGVAVPHTTRPRKSHEREGVE 433
Query 528 YHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN 587
YHFVS+QAFEADI KF+EHGE ++NLYGTS+++++ V+ K+CL+ + ++L+ LR
Sbjct 434 YHFVSKQAFEADIQHNKFLEHGEHKENLYGTSLEAIQTVMAKNKVCLVDVEPEALRHLRT 493
Query 588 SDLKPYIIFIAPPSQERLRA-LLAKEGKNPK---PEELREIIEKTREMEQNNGHYFDTAI 643
+ KPY+IF+ P QE+ + ++ + ++P E+ +E+ ++Q+ GH DT +
Sbjct 494 PEFKPYVIFVKPAIQEKRKTPPVSPDSEDPATPLDEQQQEMAASAAFIDQHYGHLIDTVL 553
Query 644 VNSDLDKAYQELLRLINKLDTEPQWVPSTWLR 675
V DL +L +I L + WVP +W+R
Sbjct 554 VRQDLQSVCSQLRAVIESLSKDTYWVPISWVR 585
>sp|O14936|CSKP_HUMAN Peripheral plasma membrane protein CASK
OS=Homo sapiens OX=9606 GN=CASK PE=1 SV=3
Length=926
Score = 536 bits (1382), Expect = 4e-179, Method: Composition-based stats.
Identities = 185/668 (28%), Positives = 337/668 (50%), Gaps = 82/668 (12%)
Query 59 IRQQQEDMRR---RREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESP 115
+ + E +R+ RR+ +G L SS + PP + D E
Sbjct 288 LPETVEQLRKFNARRKLKGAV--LAAVSSHKFNSFYGDPP-----EELPDFSEDPTSSGL 340
Query 116 HYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNK 175
A + + + SL+ I H L D S++D+ L + Q++ +++ I +
Sbjct 341 LAAERA--VSQVLDSLEEI-HALTDC-SEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSP 396
Query 176 --ASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVA----- 228
+PP + A+++ +E+ + + + +EL +L PH ALL HD VA
Sbjct 397 QIRNPPSDAVQRAKEVLEEISCYPE---NNDAKELKRILTQPHFMALLQTHDVVAHEVYS 453
Query 229 EQEMQLEPIT------DERVYESIGQYGGETV---KIVRIEKARDIPLGATVR-NEMDSV 278
++ +++ P + + G E V ++V+ +K D P+G T++ NE++
Sbjct 454 DEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHC 513
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
I++RI+ GG + G LH GDE+ EINGI + + V ++ +L +M G++TF ++PS +
Sbjct 514 IVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRT 573
Query 339 KPPPAKETV--------------------------------IHVKAHFDYDPSDDPYVPC 366
+ + I+V+A F+YDP+ D +PC
Sbjct 574 QSSSCERDSPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPC 633
Query 367 RELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEED 426
+E G+ F+ GDI+ +IS++D NWWQ E ++ AGL+P Q+ R A +E+
Sbjct 634 KEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGT--AGLIPSPELQEWRVACI-AMEKT 690
Query 427 KEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIG 486
K+ +++ W KK K+ + K L A N +D +++TYEE+ PA +++ ++L+G
Sbjct 691 KQEQQASCTWFGKKKKQYKDKYL--AKHNAVFDQLDLVTYEEVVKL--PAFKRKTLVLLG 746
Query 487 PQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFI 546
G+ ++ L+ K DRFA +PHTTR + E G++Y+FVS DI+ +++
Sbjct 747 AHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYL 806
Query 547 EHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLR 606
E+G E +YGT ++++R++ G I +L + Q+LK LR ++ P+++FIA P+
Sbjct 807 EYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTI---- 862
Query 607 ALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEP 666
G N + E L+ + +++ +++ HYFD I+N+++D+ + L + + T P
Sbjct 863 ----TPGLN-EDESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAP 917
Query 667 QWVPSTWL 674
QWVP +W+
Sbjct 918 QWVPVSWV 925
>sp|O70589|CSKP_MOUSE Peripheral plasma membrane protein CASK
OS=Mus musculus OX=10090 GN=Cask PE=1 SV=2
Length=926
Score = 536 bits (1382), Expect = 4e-179, Method: Composition-based stats.
Identities = 185/668 (28%), Positives = 337/668 (50%), Gaps = 82/668 (12%)
Query 59 IRQQQEDMRR---RREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESP 115
+ + E +R+ RR+ +G L SS + PP + D E
Sbjct 288 LPETVEQLRKFNARRKLKGAV--LAAVSSHKFNSFYGDPP-----EELPDFSEDPTSSGL 340
Query 116 HYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNK 175
A + + + SL+ I H L D S++D+ L + Q++ +++ I +
Sbjct 341 LAAERA--VSQVLDSLEEI-HALTDC-SEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSP 396
Query 176 --ASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVA----- 228
+PP + A+++ +E+ + + + +EL +L PH ALL HD VA
Sbjct 397 QIRNPPSDAVQRAKEVLEEISCYPE---NNDAKELKRILTQPHFMALLQTHDVVAHEVYS 453
Query 229 EQEMQLEPIT------DERVYESIGQYGGETV---KIVRIEKARDIPLGATVR-NEMDSV 278
++ +++ P + + G E V ++V+ +K D P+G T++ NE++
Sbjct 454 DEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHC 513
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
I++RI+ GG + G LH GDE+ EINGI + + V ++ +L +M G++TF ++PS +
Sbjct 514 IVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRT 573
Query 339 KPPPAKETV--------------------------------IHVKAHFDYDPSDDPYVPC 366
+ + I+V+A F+YDP+ D +PC
Sbjct 574 QSSSCERDSPSTSRQSPANGHSSTNNSVSDLPSTTQPKGRQIYVRAQFEYDPAKDDLIPC 633
Query 367 RELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEED 426
+E G+ F+ GDI+ +IS++D NWWQ E ++ AGL+P Q+ R A +E+
Sbjct 634 KEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGT--AGLIPSPELQEWRVACI-AMEKT 690
Query 427 KEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIG 486
K+ +++ W KK K+ + K L A N +D +++TYEE+ PA +++ ++L+G
Sbjct 691 KQEQQASCTWFGKKKKQYKDKYL--AKHNAVFDQLDLVTYEEVVKL--PAFKRKTLVLLG 746
Query 487 PQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFI 546
G+ ++ L+ K DRFA +PHTTR + E G++Y+FVS DI+ +++
Sbjct 747 AHGVGRRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYL 806
Query 547 EHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLR 606
E+G E +YGT ++++R++ G I +L + Q+LK LR ++ P+++FIA P+
Sbjct 807 EYGSHEDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFIAAPTI---- 862
Query 607 ALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEP 666
G N + E L+ + +++ +++ HYFD I+N+++D+ + L + + T P
Sbjct 863 ----TPGLN-EDESLQRLQKESDVLQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAP 917
Query 667 QWVPSTWL 674
QWVP +W+
Sbjct 918 QWVPVSWV 925
>sp|Q62915|CSKP_RAT Peripheral plasma membrane protein CASK OS=Rattus
norvegicus OX=10116 GN=Cask PE=1 SV=1
Length=909
Score = 527 bits (1357), Expect = 1e-175, Method: Composition-based stats.
Identities = 183/656 (28%), Positives = 338/656 (52%), Gaps = 75/656 (11%)
Query 59 IRQQQEDMRR---RREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIVLESP 115
+ + E +R+ RR+ +G L SS + PP + D E
Sbjct 288 LPETVEQLRKFNARRKLKGAV--LAAVSSHKFNSFYGDPP-----EELPDFSEDPTSSGL 340
Query 116 HYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNK 175
A + + + SL+ I H L D S++D+ L + Q++ +++ I +
Sbjct 341 LAAERA--VSQVLDSLEEI-HALTDC-SEKDLDFLHSVFQDQHLHTLLDLYDKINTKSSP 396
Query 176 --ASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVA----- 228
+PP + A+++ +E+ + + + +EL +L PH ALL H VA
Sbjct 397 QIRNPPSDAVQRAKEVLEEISCYPE---NNDAKELKRILTQPHFMALLQTHHVVAHEVYS 453
Query 229 EQEMQLEPIT------DERVYESIGQYGGETV---KIVRIEKARDIPLGATVR-NEMDSV 278
++ +++ P + + G E V ++V+ +K D P+G T++ NE++
Sbjct 454 DEALRVTPPPTSPYLNGDSPESANGDMDMENVTRVRLVQFQKNTDEPMGITLKMNELNHC 513
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
I++RI+ GG + G LH GDE+ EINGI + + V ++ +L +M G++TF ++PS +
Sbjct 514 IVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKMLREMRGSITFKIVPSYRT 573
Query 339 K--------PPPAKET------------VIHVKAHFDYDPSDDPYVPCRELGLSFQKGDI 378
+ P ++++ I+V+A F+YDP+ D +PC+E G+ F+ GDI
Sbjct 574 QSSSCERDSPSTSRQSPANGHSSTNNSVSIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDI 633
Query 379 LHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCA 438
+ +IS++D NWWQ E ++ AGL+P Q+ R A +E+ K+ +++ W
Sbjct 634 IQIISKDDHNWWQGKLENSKNGT--AGLIPSPELQEWRVACI-AMEKTKQEQQASCTWFG 690
Query 439 KKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQR 498
KK K+ + K L A N +++TYEE+ PA +++ ++L+G G+ ++
Sbjct 691 KKKKQYKDKYL--AKHNA-----DLVTYEEVVKL--PAFKRKTLVLLGAHGVGRRHIKNT 741
Query 499 LMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGT 558
L+ K +RFA +PHTTR + E G++Y+FVS DI+ +++E+G E +YGT
Sbjct 742 LITKHPERFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGT 801
Query 559 SIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKP 618
++++R++ G I +L + Q+LK LR ++ P+++FIA P+ G N +
Sbjct 802 KLETIRKIHEQGLIAILDVEPQALKVLRTAEFPPFVVFIAAPTI--------TPGLN-ED 852
Query 619 EELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
E L+ + +++ +++ HYFD I+N+++D+ + L + + T PQWVP +W+
Sbjct 853 ESLQRLQKESDVLQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWV 908
>sp|Q6P7F1|MPP4_MOUSE MAGUK p55 subfamily member 4 OS=Mus musculus
OX=10090 GN=Mpp4 PE=1 SV=1
Length=635
Score = 511 bits (1316), Expect = 5e-173, Method: Composition-based stats.
Identities = 194/593 (33%), Positives = 302/593 (51%), Gaps = 77/593 (13%)
Query 147 ISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVL-KPVHHKEG 205
+ LL L+ + Q K+++ + K P ++AQ LA EV +L K E
Sbjct 49 LCLLYDLLHSPWLQALLKVYDCLQRFKEKKL--VPDTTHAQILACEVLELLPKASGSPEI 106
Query 206 QELTALLNTPHIQALLLAHDKVAEQEMQ-LEPITDERVYESIGQYGGETVKIVRIEKARD 264
QEL +L PH +ALL AHD VA+++ + L P + + +S E ++IV + K +
Sbjct 107 QELRQVLQAPHCKALLSAHDTVAQKDFEPLLPPLPDNIPDS-----EEAMRIVCLVKNQQ 161
Query 265 IPLGATVRNE--MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
PLGAT++ ++++R++ GG E+SGLL+ GD+++E+NG+ + G D +V +L+
Sbjct 162 -PLGATIKRHEITGDILVARVIHGGLVERSGLLYAGDKLVEVNGVSVEGLDPEQVIHILA 220
Query 323 DMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVI 382
GT+ F +IP PP + + +++V+A DY P +DP +PC + GL F KGDIL ++
Sbjct 221 MSCGTIMFKVIPVS--APPVSSQKMVYVRAMIDYWPQEDPDIPCMDAGLPFLKGDILQIV 278
Query 383 SQEDPNWWQAYREGDEDNQPLAGLVPGKSF--QQQREAMKQ------------------- 421
Q D WWQA + D AGL+P ++QRE
Sbjct 279 DQNDALWWQARKISD--LTICAGLIPSNHLLKRKQREFWWSQPYQPHTCLKSTRALSMEE 336
Query 422 ------------------TIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEI 463
EE E + K ++ + + +
Sbjct 337 EDSMKIDEKCVEADEETFESEELAEAKDEFVGDGQKFFIAGFRRSMRLCRRKSHFSQLHA 396
Query 464 LT-------------YEEMSLY-HQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFAS 509
YEE+ Y QPA++ R I+L+GP G NELR++L+ F S
Sbjct 397 SLCCSCSCYSAVGAPYEEVVRYQRQPADKHRLIVLVGPSGVGVNELRRQLIGCNPSCFQS 456
Query 510 AVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINS 569
AVPHTTR + E+ GR+YH+VSR+ FE+ + K +E+GE++ +LYGTS+++V V++
Sbjct 457 AVPHTTRFPKSYEMDGREYHYVSRETFESLMYGHKMLEYGEYKGHLYGTSVNAVHAVLDE 516
Query 570 GKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLR--ALLAKEGKN------PKPEEL 621
GKIC++ L Q +++ R DLKPY+IFI PP+ +R AK + K E+L
Sbjct 517 GKICIMDLEPQDIQSARTRDLKPYVIFIKPPNTSSMRHSRKNAKITTDYYVDMKFKDEDL 576
Query 622 REIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
+E+ E ++ME G +FD IVN +L A +LL I K E QWVP W+
Sbjct 577 QEMEELAQKMESQFGQFFDHVIVNDNLQDACGQLLSAIQKAQEELQWVPEAWV 629
>sp|D3ZAA9|MPP2_RAT MAGUK p55 subfamily member 2 OS=Rattus norvegicus
OX=10116 GN=Mpp2 PE=1 SV=2
Length=552
Score = 504 bits (1298), Expect = 1e-171, Method: Composition-based stats.
Identities = 190/560 (34%), Positives = 310/560 (55%), Gaps = 29/560 (5%)
Query 124 IEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLI 183
++ + +L + + ++ D+ L ++++ ++ K H + +A +
Sbjct 12 MQQVLDNLGSLPNA--TGAAELDLIFLRGIMESPIVRSLAKAHERLEETKLEA-----VR 64
Query 184 SNAQDLAQEVQTVLKPVH--HKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDER 241
N +L QE+ L + EL +L PH Q+LL HD VA + + P +
Sbjct 65 DNNLELVQEILRDLAELAEQSSTAAELARILQEPHFQSLLETHDSVASKTYETPPPSPGL 124
Query 242 VYESIGQ-YGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
Q + V++V I K LG T R E ++I+RI+ GG + GLLH GD
Sbjct 125 DPTFSNQPVPPDAVRMVGIRKTAGEHLGVTFRVEGGELVIARILHGGMVAQQGLLHVGDI 184
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
+ E+NG + G D + +LL G++ ++PS Q P + + VK HFDYDP+
Sbjct 185 IKEVNGQPV-GSDPRALQELLRSASGSVILKILPSYQEPHLPRQ---VFVKCHFDYDPAR 240
Query 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
D +PC+E GL F GD+L +++Q+D NWWQA AGL+P + +++R+A
Sbjct 241 DSLIPCKEAGLRFNAGDLLQIVNQDDANWWQACHV----EGGSAGLIPSQLLEEKRKAF- 295
Query 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
++ D E + C + KK+K+++Y KN ++D E+L YEE++ P R++
Sbjct 296 --VKRDLELTPTSGTLCGSLSGKKKKRMMYLTTKNAEFDRHELLIYEEVA--RMPPFRRK 351
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
++LIG Q G+ L+ +L+ + DR+ + VP+T+R +D E G+ Y FVSR EADI
Sbjct 352 TLVLIGAQGVGRRSLKNKLILWDPDRYGTTVPYTSRRPKDSEREGQGYSFVSRGEMEADI 411
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
AG+++EHGE+E NLYGT IDS+R V+ SGK+C+L + Q++K LR ++ PY++FI P
Sbjct 412 RAGRYLEHGEYEGNLYGTRIDSIRGVVASGKVCVLDVNPQAVKVLRTAEFVPYVVFIEAP 471
Query 601 SQERLRALLAK------EGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
E LRA+ K +LR +E++ +++ GHYFD ++VNS+L++ ++E
Sbjct 472 DFETLRAMNRAALESGVSTKQLTEADLRRTVEESSRIQRGYGHYFDLSLVNSNLERTFRE 531
Query 655 LLRLINKLDTEPQWVPSTWL 674
L + KL TEPQWVP +W+
Sbjct 532 LQTAMEKLRTEPQWVPVSWV 551
>sp|Q14168|MPP2_HUMAN MAGUK p55 subfamily member 2 OS=Homo sapiens
OX=9606 GN=MPP2 PE=1 SV=3
Length=576
Score = 503 bits (1294), Expect = 1e-170, Method: Composition-based stats.
Identities = 191/583 (33%), Positives = 312/583 (54%), Gaps = 46/583 (8%)
Query 120 KILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPP 179
+ ++ D SL ++ D+ L ++++ ++ K+ + P
Sbjct 11 AMQQVLDNLGSLPSATGA-----AELDLIFLRGIMESPIVRSLAKVIMVLWFMQQNVFVP 65
Query 180 FPLI---SNAQDLAQE-------------VQTVLKPVHHKEGQ-----ELTALLNTPHIQ 218
+ A + +E VQ +L+ + H Q EL +L PH Q
Sbjct 66 MKYMLKYFGAHERLEETKLEAVRDNNLELVQEILRDLAHVAEQSSTAAELAHILQEPHFQ 125
Query 219 ALLLAHDKVAEQEMQLEPITDERVYESIGQ-YGGETVKIVRIEKARDIPLGATVRNEMDS 277
+LL HD VA + + P + Q + V++V I K LG T R E
Sbjct 126 SLLETHDSVASKTYETPPPSPGLDPTFSNQPVPPDAVRMVGIRKTAGEHLGVTFRVEGGE 185
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
++I+RI+ GG + GLLH GD + E+NG + G D + +LL + G++ ++PS Q
Sbjct 186 LVIARILHGGMVAQQGLLHVGDIIKEVNGQPV-GSDPRALQELLRNASGSVILKILPSYQ 244
Query 338 IKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGD 397
P + + VK HFDYDP+ D +PC+E GL F GD+L +++Q+D NWWQA
Sbjct 245 EPHLPRQ---VFVKCHFDYDPARDSLIPCKEAGLRFNAGDLLQIVNQDDANWWQACHV-- 299
Query 398 EDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDD 457
AGL+P + +++R+A ++ D E + C + KK+K+++Y KN +
Sbjct 300 --EGGSAGLIPSQLLEEKRKAF---VKRDLELTPNSGTLCGSLSGKKKKRMMYLTTKNAE 354
Query 458 YDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRS 517
+D E+L YEE++ P R++ ++LIG Q G+ L+ +L+ + DR+ + VP+T+R
Sbjct 355 FDRHELLIYEEVA--RMPPFRRKTLVLIGAQGVGRRSLKNKLIMWDPDRYGTTVPYTSRR 412
Query 518 RRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSL 577
+D E G+ Y FVSR EAD+ AG+++EHGE+E NLYGT IDS+R V+ +GK+C+L +
Sbjct 413 PKDSEREGQGYSFVSRGEMEADVRAGRYLEHGEYEGNLYGTRIDSIRGVVAAGKVCVLDV 472
Query 578 RTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAK------EGKNPKPEELREIIEKTREM 631
Q++K LR ++ PY++FI P E LRA+ K +LR +E++ +
Sbjct 473 NPQAVKVLRTAEFVPYVVFIEAPDFETLRAMNRAALESGISTKQLTEADLRRTVEESSRI 532
Query 632 EQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
++ GHYFD +VNS+L++ ++EL + KL TEPQWVP +W+
Sbjct 533 QRGYGHYFDLCLVNSNLERTFRELQTAMEKLRTEPQWVPVSWV 575
>sp|Q9WV34|MPP2_MOUSE MAGUK p55 subfamily member 2 OS=Mus musculus
OX=10090 GN=Mpp2 PE=1 SV=1
Length=552
Score = 501 bits (1290), Expect = 2e-170, Method: Composition-based stats.
Identities = 190/560 (34%), Positives = 309/560 (55%), Gaps = 29/560 (5%)
Query 124 IEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLI 183
++ + +L + + ++ D+ L ++++ ++ K H + +A +
Sbjct 12 MQQVLDNLGSLPNA--TGAAELDLIFLRGIMESPIVRSLAKAHERLEETKLEA-----VR 64
Query 184 SNAQDLAQEVQTVLKPVH--HKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDER 241
N +L QE+ L + EL +L PH Q+LL HD VA + + P +
Sbjct 65 DNNLELVQEILRDLAELAEQSSTAAELARILQEPHFQSLLETHDSVASKTYETPPPSPGL 124
Query 242 VYESIGQ-YGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
Q + V++V I K LG T R E ++I+RI+ GG + GLLH GD
Sbjct 125 DPTFSNQPVPPDAVRMVGIRKTAGEHLGVTFRVEGGELVIARILHGGMVAQQGLLHVGDI 184
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
+ E+NG + G D + +LL G++ ++PS Q P + + VK HFDYDP+
Sbjct 185 IKEVNGQPV-GSDPRALQELLRSASGSVILKILPSYQEPHLPRQ---VFVKCHFDYDPAR 240
Query 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
D PC+E GL F GD+L +++Q+D NWWQA AGL+P + +++R+A
Sbjct 241 DSLSPCKEAGLRFNAGDLLQIVNQDDANWWQACHV----EGGSAGLIPSQLLEEKRKAF- 295
Query 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKR 480
++ D E + C + KK+K+++Y KN ++D E+L YEE++ P R++
Sbjct 296 --VKRDLELTPTSGTLCGSLSGKKKKRMMYLTTKNAEFDRHELLIYEEVA--RMPPFRRK 351
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
++LIG Q G+ L+ +L+ + DR+ + VP+T+R +D E G+ Y FVSR EADI
Sbjct 352 TLVLIGAQGVGRRSLKNKLILWDPDRYGTTVPYTSRRPKDSEREGQGYSFVSRGEMEADI 411
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
AG+++EHGE+E NLYGT IDS+R V+ SGK+C+L + Q++K LR ++ PY++FI P
Sbjct 412 RAGRYLEHGEYEGNLYGTRIDSIRGVVASGKVCVLDVNPQAVKVLRTAEFVPYVVFIEAP 471
Query 601 SQERLRALLAK------EGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
E LRA+ K +LR +E++ +++ GHYFD ++VNS+L++ ++E
Sbjct 472 DYETLRAMNRAALESGVSTKQLTEADLRRTVEESSRIQRGYGHYFDLSLVNSNLERTFRE 531
Query 655 LLRLINKLDTEPQWVPSTWL 674
L + KL TEPQWVP +W+
Sbjct 532 LQTAMEKLRTEPQWVPVSWV 551
>sp|Q9JLB0|PALS2_MOUSE Protein PALS2 OS=Mus musculus OX=10090
GN=Pals2 PE=1 SV=1
Length=553
Score = 500 bits (1288), Expect = 4e-170, Method: Composition-based stats.
Identities = 193/571 (34%), Positives = 319/571 (56%), Gaps = 39/571 (7%)
Query 124 IEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLI 183
++ + +L + + + D+ L +++N ++ K H + +A +
Sbjct 1 MQQVLENLTELPSS--TGAEEIDLIFLKGIMENPIVKSLAKAHERLEDSKLEA-----VS 53
Query 184 SNAQDLAQEVQTVLKPVHHKEGQ--ELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE- 240
N +L E+ + P+ + EL +L PH Q+LL AHD VA + P + E
Sbjct 54 DNNLELVNEILEDITPLISVDENVAELVGILKEPHFQSLLEAHDIVASKCYDSPPSSPEM 113
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
+ Q + ++I+ I K PLG T R E + ++I+RI+ GG ++ GLLH GD
Sbjct 114 NIPSLNNQLPVDAIRILGIHKKAGEPLGVTFRVENNDLVIARILHGGMIDRQGLLHVGDI 173
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKE-----------TVIH 349
+ E+NG E+ G + E+ +LL ++ G++T ++PS + P + +
Sbjct 174 IKEVNGHEV-GNNPKELQELLKNISGSVTLKILPSYRDTITPQQSYVNMERHPAHVRQVF 232
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
VK HFDY+P +D +PC+E GL F KG+IL ++++EDPNWWQA + + AGL+P
Sbjct 233 VKCHFDYNPFNDNLIPCKEAGLKFSKGEILQIVNREDPNWWQASHVKEGGS---AGLIPS 289
Query 410 KSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEM 469
+ +++R+A + ++ P +C + KK+KK++Y +N ++D EI YEE+
Sbjct 290 QFLEEKRKAFVRRDWDNSGP------FCGTISNKKKKKMMYLTTRNAEFDRHEIQIYEEV 343
Query 470 SLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYH 529
+ P +++ ++LIG Q G+ L+ R + RF + VP T+R R+ E G+ Y
Sbjct 344 A--KMPPFQRKTLVLIGAQGVGRRSLKNRFIVLNPARFGTTVPFTSRKPREDEKDGQAYK 401
Query 530 FVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD 589
FVSR EADI AGK++EHGE+E NLYGT IDS+ +V+ +G+ C+L + Q+LK LR S+
Sbjct 402 FVSRSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTSE 461
Query 590 LKPYIIFIAPPSQERLRAL---LAKEGKNPK---PEELREIIEKTREMEQNNGHYFDTAI 643
PY++FIA P E LRA+ + G K +L++ ++++ +++ HYFD I
Sbjct 462 FMPYVVFIAAPELETLRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAYNHYFDLII 521
Query 644 VNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
VN +LDKA+++L I KL EPQWVP +W+
Sbjct 522 VNDNLDKAFEKLQTAIEKLRMEPQWVPISWV 552
>sp|Q96JB8|MPP4_HUMAN MAGUK p55 subfamily member 4 OS=Homo sapiens
OX=9606 GN=MPP4 PE=1 SV=2
Length=637
Score = 500 bits (1288), Expect = 7e-169, Method: Composition-based stats.
Identities = 194/593 (33%), Positives = 307/593 (52%), Gaps = 77/593 (13%)
Query 147 ISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPV-HHKEG 205
+ LL L+ + Q KI++ + K P +AQ L+ EV +L+ E
Sbjct 50 VCLLYDLLHSPWLQALLKIYDCLQEFKEKKL--VPATPHAQVLSYEVVELLRETPTSPEI 107
Query 206 QELTALLNTPHIQALLLAHDKVAEQEMQ-LEPITDERVYESIGQYGGETVKIVRIEKARD 264
QEL +L PH +ALL AHD +A+++ + L P + + ES E ++IV + K +
Sbjct 108 QELRQMLQAPHFKALLSAHDTIAQKDFEPLLPPLPDNIPES-----EEAMRIVCLVKNQQ 162
Query 265 IPLGATV-RNEMDS-VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
PLGAT+ R+EM ++++RI+ GG AE+SGLL+ GD+++E+NG+ + G D +V +L+
Sbjct 163 -PLGATIKRHEMTGDILVARIIHGGLAERSGLLYAGDKLVEVNGVSVEGLDPEQVIHILA 221
Query 323 DMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVI 382
GT+ F ++P PP + +++V+A +Y P +DP +PC + GL FQKGDIL ++
Sbjct 222 MSRGTIMFKVVPVS--DPPVNSQQMVYVRAMTEYWPQEDPDIPCMDAGLPFQKGDILQIV 279
Query 383 SQEDPNWWQAYREGDEDNQPLAGLVPGKSF--QQQREAMKQ------------------- 421
Q D WWQA + D AGLVP ++QRE
Sbjct 280 DQNDALWWQARKISDPA--TCAGLVPSNHLLKRKQREFWWSQPYQPHTCLKSTLSISMEE 337
Query 422 ------------------TIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEI 463
EE E ++ + K ++ + +
Sbjct 338 EDDMKIDEKCVEADEETFESEELSEDKEEFVGYGQKFFIAGFRRSMRLCRRKSHLSPLHA 397
Query 464 LT-------------YEEMSLY-HQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFAS 509
YEE+ Y +P+++ R I+L+GP G NELR++L+ F S
Sbjct 398 SVCCTGSCYSAVGAPYEEVVRYQRRPSDKYRLIVLMGPSGVGVNELRRQLIEFNPSHFQS 457
Query 510 AVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINS 569
AVPHTTR+++ E+ GR+YH+VS++ FE I + + +E+GE++ +LYGTS+D+V+ V+
Sbjct 458 AVPHTTRTKKSYEMNGREYHYVSKETFENLIYSHRMLEYGEYKGHLYGTSVDAVQTVLVE 517
Query 570 GKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLR--ALLAKEGKN------PKPEEL 621
GKIC++ L Q ++ +R +LKPY+IFI P + ++ AK + K E+L
Sbjct 518 GKICVMDLEPQDIQGVRTHELKPYVIFIKPSNMRCMKQSRKNAKVITDYYVDMKFKDEDL 577
Query 622 REIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
+E+ + ME G +FD IVN L A +LL I K EPQWVP+TW+
Sbjct 578 QEMENLAQRMETQFGQFFDHVIVNDSLHDACAQLLSAIQKAQEEPQWVPATWI 630
>sp|O88910|MPP3_MOUSE MAGUK p55 subfamily member 3 OS=Mus musculus
OX=10090 GN=Mpp3 PE=1 SV=2
Length=568
Score = 496 bits (1278), Expect = 2e-168, Method: Composition-based stats.
Identities = 191/549 (35%), Positives = 315/549 (57%), Gaps = 50/549 (9%)
Query 140 DSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKP 199
DS +E++ L + K KIH + + ++ P P++ +A LA++V L+
Sbjct 24 DSNHREEMGFLRDVFSEKSLSYLMKIHEKLRYYERQS--PTPVLHSAMALAEDVMEELQA 81
Query 200 VH-HKEGQELTALLNTPHIQALLLAHDKVAEQEMQ--LEPITDERVYESIGQYGGETVKI 256
H + +EL LL+TPH++A+L+ HD VA++ L P+ D + + E+VKI
Sbjct 82 ASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDED----FEEESVKI 137
Query 257 VRIEKARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
VR+ K ++ PLGAT+R + S V+++RI++GGAA++SGL+H GDE+ E+NGI + K
Sbjct 138 VRLVKNKE-PLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRP 196
Query 315 NEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQ 374
+E+ +L+ G++T +IP+ Q + K++ + ++A F YDP +D +PC+E GL FQ
Sbjct 197 DEISQILAQSQGSITLKIIPATQ-EEDRFKDSKVFMRALFHYDPREDRAIPCQEAGLPFQ 255
Query 375 KGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEK--- 431
+ +L V+SQ+DP WWQA R GD + AGL+P K FQ++R + ++T P+
Sbjct 256 RRQVLEVVSQDDPTWWQAKRVGDTNL--RAGLIPSKQFQERRLSYRRTTGTLPSPQNFKK 313
Query 432 -----------------------SGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEE 468
+G + ++R A +++ +LTYEE
Sbjct 314 PPYDQPCDKETCDCDGYFKGHYVAGLRRSFRLGCRERLGGSQEAKVPTGAESQVLLTYEE 373
Query 469 MSLY-HQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRD 527
++ Y HQP R R ++LIG +EL+QR++ ++ +FA AVPHTTR R+ E G +
Sbjct 374 VARYQHQPGERPRLVVLIGSLGAHLHELKQRVVAEDPQQFAVAVPHTTRPRKSHERDGVE 433
Query 528 YHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN 587
YHFVS+QAFEAD+ KF+EHGE+++NLYGTS+++++ V+ K+CL+ + ++L+ LR
Sbjct 434 YHFVSKQAFEADVHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALRHLRT 493
Query 588 SDLKPYIIFIAPPSQERLRALLAKEGKNPK------PEELREIIEKTREMEQNNGHYFDT 641
+ KPY+IF+ P QE R + + E+ +E+ ++Q+ GH DT
Sbjct 494 PEFKPYVIFVKPAIQE--RRKTPPVSPDSEDIASSLDEQQQEMAASAAFIDQHYGHLIDT 551
Query 642 AIVNSDLDK 650
+V DL +
Sbjct 552 VLVRQDLQE 560
>sp|Q9NZW5|PALS2_HUMAN Protein PALS2 OS=Homo sapiens OX=9606 GN=PALS2
PE=1 SV=2
Length=540
Score = 489 bits (1260), Expect = 5e-166, Method: Composition-based stats.
Identities = 193/561 (34%), Positives = 320/561 (57%), Gaps = 32/561 (6%)
Query 124 IEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLI 183
++ + +L + + + D+ L +++N ++ K H + +A +
Sbjct 1 MQQVLENLTELPSS--TGAEEIDLIFLKGIMENPIVKSLAKAHERLEDSKLEA-----VS 53
Query 184 SNAQDLAQEVQTVLKPVHHKEGQ--ELTALLNTPHIQALLLAHDKVAEQEMQLEPITDER 241
N +L E+ + P+ + + EL +L PH Q+LL AHD VA + P + E
Sbjct 54 DNNLELVNEILEDITPLINVDENVAELVGILKEPHFQSLLEAHDIVASKCYDSPPSSPEM 113
Query 242 VYESIGQ--YGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGD 299
SI + ++I+ I K PLG T R E + ++I+RI+ GG ++ GLLH GD
Sbjct 114 NNSSINNQLLPVDAIRILGIHKRAGEPLGVTFRVENNDLVIARILHGGMIDRQGLLHVGD 173
Query 300 EVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPS 359
+ E+NG E+ G + E+ +LL ++ G++T ++PS + P + + VK HFDY+P
Sbjct 174 IIKEVNGHEV-GNNPKELQELLKNISGSVTLKILPSYRDTITPQQ---VFVKCHFDYNPY 229
Query 360 DDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAM 419
+D +PC+E GL F KG+IL ++++EDPNWWQA + + AGL+P + +++R+A
Sbjct 230 NDNLIPCKEAGLKFSKGEILQIVNREDPNWWQASHVKEGGS---AGLIPSQFLEEKRKAF 286
Query 420 KQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRK 479
+ ++ P +C + KK+KK++Y +N ++D EI YEE++ P ++
Sbjct 287 VRRDWDNSGP------FCGTISSKKKKKMMYLTTRNAEFDRHEIQIYEEVA--KMPPFQR 338
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
+ ++LIG Q G+ L+ R + RF + VP T+R R+ E G+ Y FVSR EAD
Sbjct 339 KTLVLIGAQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKDGQAYKFVSRSEMEAD 398
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
I AGK++EHGE+E NLYGT IDS+ +V+ +G+ C+L + Q+LK LR S+ PY++FIA
Sbjct 399 IKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRTSEFMPYVVFIAA 458
Query 600 PSQERLRAL---LAKEGKNPK---PEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
P E LRA+ + G K +L++ ++++ +++ HYFD I+N +LDKA++
Sbjct 459 PELETLRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAYNHYFDLIIINDNLDKAFE 518
Query 654 ELLRLINKLDTEPQWVPSTWL 674
+L I KL EPQWVP +W+
Sbjct 519 KLQTAIEKLRMEPQWVPISWV 539
>sp|Q17QN6|EM55_BOVIN 55 kDa erythrocyte membrane protein OS=Bos
taurus OX=9913 GN=MPP1 PE=1 SV=1
Length=466
Score = 458 bits (1179), Expect = 7e-155, Method: Composition-based stats.
Identities = 142/489 (29%), Positives = 258/489 (53%), Gaps = 35/489 (7%)
Query 196 VLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGET-- 253
LK + G + L+ +++ LL H++ QL + ++ G
Sbjct 2 TLKASEGEGGGGMRTALSDLYLEHLLQKHNRPEPVSPQLSAVMEDMYTNGPAALGSPAQT 61
Query 254 -------VKIVRIEKARDIPLGATVR-NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
V++++ EK + P+G T++ NE S ++RI+ GG + G LH GDE+LEIN
Sbjct 62 QGQEARKVRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMVHRQGSLHVGDEILEIN 121
Query 306 GIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVP 365
G + V+++ + + G ++ +IP+QQ + P + + ++A FDYDP D +P
Sbjct 122 GTNVTNHSVDQLQKAMKETKGMISLKVIPNQQNRLPALQ---MFMRAQFDYDPRKDNLIP 178
Query 366 CRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEE 425
C+E GL F GD++ +I+++D NWWQ EG Q AGL+P Q+ R A
Sbjct 179 CKEAGLKFLTGDVIQIINKDDSNWWQGRVEGSS--QESAGLIPSPELQEWRVASGAHSAP 236
Query 426 DKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILI 485
+ P C+ KKK+ K Y A + +D ++++YEE+ PA +++ ++LI
Sbjct 237 SEAPS------CSPFGKKKKYKDKYLAKHSAIFDQLDVVSYEEVV--RLPAFKRKTLVLI 288
Query 486 GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKF 545
G G++ ++ L+++ D+FA P+TTR R E G++YHF+S + I+A +F
Sbjct 289 GASGVGRSHIKSALLSQNPDKFAYPAPYTTRPARKSEEDGKEYHFISTEEMTRSISANEF 348
Query 546 IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERL 605
+E G ++ N++GT ++V Q+ K+ +L + Q+LK +R ++L P+I+FIAP
Sbjct 349 LEFGSYQGNMFGTKFETVHQIHKQDKVAILDIEPQTLKIVRTAELSPFIVFIAPTD---- 404
Query 606 RALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTE 665
+ + + L+++ + + + HYFD ++VN+ +++ + L ++
Sbjct 405 --------QGTQTDTLQQLQKDSEAIRSQYAHYFDLSLVNNSVEETLKTLQETFDQACRS 456
Query 666 PQWVPSTWL 674
PQWVP +W+
Sbjct 457 PQWVPVSWV 465
>sp|Q00013|EM55_HUMAN 55 kDa erythrocyte membrane protein OS=Homo
sapiens OX=9606 GN=MPP1 PE=1 SV=2
Length=466
Score = 452 bits (1163), Expect = 2e-152, Method: Composition-based stats.
Identities = 143/489 (29%), Positives = 258/489 (53%), Gaps = 35/489 (7%)
Query 196 VLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGET-- 253
LK + G + L+ +++ LL + L +T++ G
Sbjct 2 TLKASEGESGGSMHTALSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQV 61
Query 254 -------VKIVRIEKARDIPLGATVR-NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
V++++ EK + P+G T++ NE S ++RI+ GG + G LH GDE+LEIN
Sbjct 62 KGQEVRKVRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEIN 121
Query 306 GIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVP 365
G + V+++ + + G ++ +IP+QQ + P + + ++A FDYDP D +P
Sbjct 122 GTNVTNHSVDQLQKAMKETKGMISLKVIPNQQSRLPALQ---MFMRAQFDYDPKKDNLIP 178
Query 366 CRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEE 425
C+E GL F GDI+ +I+++D NWWQ EG AGL+P Q+ R A
Sbjct 179 CKEAGLKFATGDIIQIINKDDSNWWQGRVEGSSKES--AGLIPSPELQEWRVASMAQSAP 236
Query 426 DKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILI 485
+ P C+ KKK+ K Y A + +D ++++YEE+ PA +++ ++LI
Sbjct 237 SEAPS------CSPFGKKKKYKDKYLAKHSSIFDQLDVVSYEEVV--RLPAFKRKTLVLI 288
Query 486 GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKF 545
G G++ ++ L+++ ++F VP+TTR R E G++YHF+S + +I+A +F
Sbjct 289 GASGVGRSHIKNALLSQNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEF 348
Query 546 IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERL 605
+E G ++ N++GT ++V Q+ KI +L + Q+LK +R ++L P+I+FIAP
Sbjct 349 LEFGSYQGNMFGTKFETVHQIHKQNKIAILDIEPQTLKIVRTAELSPFIVFIAPTD---- 404
Query 606 RALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTE 665
+ + E L+++ + + + HYFD ++VN+ +D+ ++L ++ +
Sbjct 405 --------QGTQTEALQQLQKDSEAIRSQYAHYFDLSLVNNGVDETLKKLQEAFDQACSS 456
Query 666 PQWVPSTWL 674
PQWVP +W+
Sbjct 457 PQWVPVSWV 465
>sp|Q5RDW4|EM55_PONAB 55 kDa erythrocyte membrane protein OS=Pongo
abelii OX=9601 GN=MPP1 PE=2 SV=1
Length=466
Score = 451 bits (1160), Expect = 6e-152, Method: Composition-based stats.
Identities = 143/489 (29%), Positives = 258/489 (53%), Gaps = 35/489 (7%)
Query 196 VLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGET-- 253
LK + G + L+ +++ LL + L +T++ G
Sbjct 2 TLKASEGESGGSMHTALSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQV 61
Query 254 -------VKIVRIEKARDIPLGATVR-NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
V++++ EK + P+G T++ NE S ++RI+ GG + G LH GDE+LEIN
Sbjct 62 KGQEVRKVRLIQFEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEIN 121
Query 306 GIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVP 365
G + V+++ + + G ++ +IP+QQ + P + + ++A FDYDP D +P
Sbjct 122 GTNVTNHSVDQLQKAMKETKGMISLKVIPNQQSRLPALQ---MFMRAQFDYDPKKDNLIP 178
Query 366 CRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEE 425
C+E GL F GDI+ +I+++D NWWQ EG AGL+P Q+ R A
Sbjct 179 CKEAGLKFATGDIIQIINKDDSNWWQGRVEGSSKES--AGLIPSPELQEWRVASVAQSAP 236
Query 426 DKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILI 485
+ P C+ KKK+ K Y A + +D ++++YEE+ PA +++ ++LI
Sbjct 237 SEAPS------CSPFGKKKKYKDKYLAKHSSIFDQLDVVSYEEVV--RLPAFKRKTLVLI 288
Query 486 GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKF 545
G G++ ++ L+++ ++F VP+TTR R E G++YHF+S + +I+A +F
Sbjct 289 GASGVGRSHIKNALLSQNPEKFVYPVPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEF 348
Query 546 IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERL 605
+E G ++ N++GT ++V Q+ KI +L + Q+LK +R ++L P+I+FIAP
Sbjct 349 LEFGSYQGNMFGTKFETVHQIHKQDKIAILDIEPQTLKIVRTAELSPFIVFIAPTD---- 404
Query 606 RALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTE 665
+ + E L+++ + + + HYFD ++VN+ +D+ ++L ++ +
Sbjct 405 --------QGTQTEALQQLQKDSEAIRSQYAHYFDLSLVNNGVDETLKKLQEAFDQACSS 456
Query 666 PQWVPSTWL 674
PQWVP +W+
Sbjct 457 PQWVPVSWV 465
>sp|A9CB74|EM55_PAPAN 55 kDa erythrocyte membrane protein OS=Papio
anubis OX=9555 GN=MPP1 PE=3 SV=1
Length=466
Score = 449 bits (1155), Expect = 2e-151, Method: Composition-based stats.
Identities = 143/489 (29%), Positives = 258/489 (53%), Gaps = 35/489 (7%)
Query 196 VLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGET-- 253
LK + G + L+ +++ LL + L +T++ G
Sbjct 2 TLKASEGESGGSMHTALSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQV 61
Query 254 -------VKIVRIEKARDIPLGATVR-NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
V++++IEK + P+G T++ NE S ++RI+ GG + G LH GDE+LEIN
Sbjct 62 KGQEVRKVRLIQIEKVTEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEIN 121
Query 306 GIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVP 365
G + V+++ + + G ++ +IP+QQ + P + + ++A FDYDP D +P
Sbjct 122 GTNVTNHSVDQLQKAMKETKGMISLKVIPNQQSRLPALQ---MFMRAQFDYDPKKDNLIP 178
Query 366 CRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEE 425
C+E GL F GDI+ +I+++D NWWQ EG AGL+P Q+ R A
Sbjct 179 CKEAGLKFATGDIIQIINKDDSNWWQGRVEGSSKES--AGLIPSPELQEWRVASIAQSAP 236
Query 426 DKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILI 485
+ P C+ KKK+ K Y A + +D ++++YEE+ PA +++ ++LI
Sbjct 237 SEAPS------CSPFGKKKKYKDKYLAKHSSIFDQLDVVSYEEVV--RLPAFKRKTLVLI 288
Query 486 GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKF 545
G G++ ++ L+++ ++F P+TTR R E G++YHF+S + +I+A +F
Sbjct 289 GASGVGRSHIKNALLSQNPEKFVYPAPYTTRPPRKSEEDGKEYHFISTEEMTRNISANEF 348
Query 546 IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERL 605
+E G ++ N++GT ++V Q+ KI +L + Q+LK +R ++L P+I+FIAP
Sbjct 349 LEFGSYQGNMFGTKFETVHQIHKQDKIAILDIEPQTLKIVRTAELSPFIVFIAPTD---- 404
Query 606 RALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTE 665
+ + E L+++ + + + HYFD ++VN+ +D+ ++L ++ +
Sbjct 405 --------QGTQTEALQQLQKDSEAIRSQYAHYFDLSLVNNSVDETLKKLQEAFDQACSS 456
Query 666 PQWVPSTWL 674
PQWVP +W+
Sbjct 457 PQWVPVSWV 465
>sp|P70290|EM55_MOUSE 55 kDa erythrocyte membrane protein OS=Mus
musculus OX=10090 GN=Mpp1 PE=1 SV=1
Length=466
Score = 444 bits (1142), Expect = 3e-149, Method: Composition-based stats.
Identities = 142/489 (29%), Positives = 257/489 (53%), Gaps = 35/489 (7%)
Query 196 VLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGET-- 253
LK + G + L+ +++ LL ++ Q T++ G
Sbjct 2 TLKSSEGEGGNSMRTALSDLYLEHLLQKRNRPETSLNQSNVTTEDMYTNGSPAPGSPAHA 61
Query 254 -------VKIVRIEKARDIPLGATVR-NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
V++++ EK + P+G T++ NE S ++RI+ GG + G LH GDE+LEIN
Sbjct 62 KGQEARRVRLIQFEKITEEPMGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEIN 121
Query 306 GIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVP 365
G + V+++ + + G ++ +I +QQ + P + + ++A FDYDP D +P
Sbjct 122 GTNVTNHSVDQLQKAMKETKGMISLKVIANQQSRLPALQ---MFMRAQFDYDPQKDNLIP 178
Query 366 CRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEE 425
C+E GL F GDI+ +I+++D NWWQ EG AGL+P Q+ R A
Sbjct 179 CKEAGLKFVTGDIIQIINKDDSNWWQGRVEGSSKES--AGLIPSPELQEWRVASVAHSAP 236
Query 426 DKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILI 485
+ P C+ KKK+ K Y A + +D ++++YEE+ PA +++ ++LI
Sbjct 237 SEAPS------CSPFGKKKKCKDKYLAKHSSIFDQLDVVSYEEVV--RLPAFKRKTLVLI 288
Query 486 GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKF 545
G G++ ++ L++ ++FA P+TTR + E G++YHF+S + +I+A +F
Sbjct 289 GASGVGRSHIKNGLLSHNPEKFAYPAPYTTRPPKKSEEDGKEYHFISTEEMTKNISANEF 348
Query 546 IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERL 605
+E G ++ N++GT ++V Q+ KI +L + Q+LKT+R ++L P+I+FIAP
Sbjct 349 LEFGSYQGNMFGTKFETVHQIHKQDKIAILDIEPQTLKTVRTAELSPFIVFIAPTD---- 404
Query 606 RALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTE 665
+ + E L+++ + + + HYFD ++VN+ +D+ ++L ++ +
Sbjct 405 --------QGTQTEALQQLQKDSEAIRSQYAHYFDLSLVNNSVDETLKKLQEAFDQACSS 456
Query 666 PQWVPSTWL 674
PQWVP +W+
Sbjct 457 PQWVPVSWV 465
>sp|Q5ZJ00|EM55_CHICK 55 kDa erythrocyte membrane protein OS=Gallus
gallus OX=9031 GN=MPP1 PE=2 SV=1
Length=468
Score = 439 bits (1128), Expect = 3e-147, Method: Composition-based stats.
Identities = 138/477 (29%), Positives = 255/477 (53%), Gaps = 35/477 (7%)
Query 208 LTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETV---------KIVR 258
+ L+ +++ LL K +T++ G + ++V+
Sbjct 16 MRTALSDLYLEHLLQNRAKPEAIAQAPNAMTEDIYTNGSATLGSPSHSNGREVRKIRLVQ 75
Query 259 IEKARDIPLGATVR-NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
EK + P+G T++ N+ S +++RI GG + G LH GDE++EING + V+++
Sbjct 76 FEKVTEEPMGITLKLNDKQSCMVARIFHGGMIHRQGSLHVGDEIIEINGQSVSNHSVDQL 135
Query 318 FDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGD 377
+L + G ++ +IP+QQ + P + + ++A FDYDP D +PC+E GL FQ GD
Sbjct 136 QKMLKETQGMVSIKVIPNQQSRLPALQ---MFMRAQFDYDPKKDNLIPCKEAGLKFQTGD 192
Query 378 ILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWC 437
++ +I+++D NWWQ EG AGL+P Q+ R A + +S C
Sbjct 193 VIQIINKDDSNWWQGRVEGSGTES--AGLIPSPELQEWRVA------SVTQSSQSEAQSC 244
Query 438 AKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQ 497
+ KKK+ K Y A + +D ++++YEE+ PA +++ ++LIG G++ ++
Sbjct 245 SPFGKKKKYKDKYLAKHSSIFDQLDVVSYEEVV--RLPAFKRKTLVLIGASGVGRSHIKN 302
Query 498 RLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYG 557
L++ ++F P+TTR ++ EV G+DY+FVS + DI+A +F+E G ++ N++G
Sbjct 303 ALLSNNPEKFMYPPPYTTRPQKKNEVDGKDYYFVSTEEMTRDISANEFLEFGSYQGNMFG 362
Query 558 TSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPK 617
T ++V ++ K+ +L + Q+LK +R ++L P+I+FIAP + +
Sbjct 363 TKFETVHKIHQQDKVAILDIEPQTLKIVRTAELSPFIVFIAPTDKAE------------E 410
Query 618 PEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
E L+++ + + + HYFD +IVN+ ++++ + L + + PQWVP +W+
Sbjct 411 SEALQQLRKDSESIRSRYAHYFDLSIVNNGVEESLKLLEEAFEQACSSPQWVPVSWV 467
>sp|P54936|LIN2_CAEEL Protein lin-2 OS=Caenorhabditis elegans
OX=6239 GN=lin-2 PE=1 SV=1
Length=961
Score = 445 bits (1144), Expect = 2e-143, Method: Composition-based stats.
Identities = 189/705 (27%), Positives = 321/705 (46%), Gaps = 105/705 (15%)
Query 50 IRRSAQL---ERIRQQQEDMRR---RREEEGKKQELDLNSSMRLKKLAQIPPKTGIDN-- 101
IR + + + + MRR R+ + + Q P+T +
Sbjct 281 IRDKEHMASRKHMNDVIDQMRRYNESRKLKSNVLSAVNSGRFDETTPRQDTPQTAFVDGS 340
Query 102 -PMFD-----TEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQ 155
P D P + + SL I ++L+D S + S Q +
Sbjct 341 SPGGDCCHRGESSSNDAAEPPADKDLSGAYKVLGSLDAI-NSLLDPNSYKPGSTTFQKIH 399
Query 156 NK-DFQNAFKIHNAITVHMNKASPPFPLISNA------QDLAQEVQTVLKPVHHKEGQEL 208
+ +N ++++ I KA P P+++ ++ ++ +L P E EL
Sbjct 400 DDGSVRNLLRLYDKI-----KALPCEPVVTEVDTSTLRKETLNQIDGLLGPS--PEALEL 452
Query 209 TALLNTPHIQALLLAHDKVAEQEMQ----------------------------LEPITDE 240
LLN+PH+ + + A D V + + P+ +
Sbjct 453 RQLLNSPHLASCVQALDVVVCEIRDPKNEASGSGDKEGNCVSSDPAPAYLNGGVLPLGAQ 512
Query 241 RVYESIGQYGGETV------------------KIVRIEKARDIPLGATVRNEMDS-VIIS 281
R S + V ++V+ +K P+G T++ D ++
Sbjct 513 RAGTSFEHFNQSAVHTSYDEEEEELYDCMSRLRLVQFQKDTQEPMGITLKVNEDGRCFVA 572
Query 282 RIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
RI+ GG + LH GDE+ EING+ + + V + ++L D G +TF +IPS + PP
Sbjct 573 RIMHGGMIHRQATLHVGDEIREINGMSVANRSVESLQEMLRDARGQVTFKIIPSYRSAPP 632
Query 342 PAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGD---- 397
+ I V+A FDY+PS D +PC + G+ F+ GDIL VIS++D NWWQA
Sbjct 633 ACE---IFVRAQFDYEPSQDDLIPCPQAGIPFKTGDILQVISKDDHNWWQARFVSSFPSI 689
Query 398 --------EDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVL 449
+ Q +AGL+P Q+ R A +E K + +W KK K K L
Sbjct 690 GNSSNAQRSNQQQVAGLIPSPELQEWRTAC-LAMERSKNTCNTHCMWFNKKKKYYTTKYL 748
Query 450 YNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFAS 509
+ +D +++TYEE+ Q R++ ++L+G G+ ++ L+++ +RFA
Sbjct 749 --QKHSALFDQLDLVTYEEVMRLSQ--YRRKTLVLLGAHGVGRRHIKNTLIHRHPNRFAY 804
Query 510 AVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINS 569
+PHTTR R EV G+ Y+FV+ + ADI +++E+G E+++YGT ++++R + S
Sbjct 805 PIPHTTRPPRKDEVDGKHYYFVTNEQMMADIQNNEYLEYGTHEESMYGTKLETIRNIHKS 864
Query 570 GKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTR 629
GKI +L + Q+LK LR ++ P+++FIA P+ + G L +++ ++
Sbjct 865 GKIAILDVEPQALKVLRTAEYSPFVVFIAAPNLQ---------GMQDPDGSLEKLLNESD 915
Query 630 EMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
+ Q GH FD I NSD+D +L RL+ KL PQW+P TW+
Sbjct 916 VLRQAFGHLFDFIITNSDIDDTIAQLERLVEKLPAYPQWLPVTWV 960
>sp|Q9QYH1|MPP4_RAT MAGUK p55 subfamily member 4 OS=Rattus norvegicus
OX=10116 GN=Mpp4 PE=1 SV=1
Length=441
Score = 426 bits (1095), Expect = 1e-142, Method: Composition-based stats.
Identities = 157/441 (36%), Positives = 250/441 (57%), Gaps = 26/441 (6%)
Query 254 VKIVRIEKARDIPLGATVRNE--MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
++ V + K + PLGAT++ ++++R++ GG E++GLL+ GD+++E+NG+ + G
Sbjct 1 MRTVCLVKNQQ-PLGATIKRHEITGDILVARVIHGGLVERNGLLYAGDKLVEVNGVPVEG 59
Query 312 KDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGL 371
D +V +L+ GT+ F +IP PP + +T ++V+A DY P +DP +PC + GL
Sbjct 60 LDPEQVIHILAMSCGTIMFKVIPVS--APPVSSQTTVYVRAMIDYWPQEDPDIPCMDAGL 117
Query 372 SFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEK 431
F KGDIL ++ Q D WWQA + D AGL+P ++++ + + +P
Sbjct 118 PFLKGDILQIVDQSDALWWQARKISD--IAICAGLIPSNHLLKRKQ-REFWWSQPYQPHT 174
Query 432 SGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILT---------YEEMSLY-HQPANRKRP 481
K +K+ + + A + N YEE+ Y QPA++ R
Sbjct 175 CLKSTRSKEEFVGDGQQFFIAGFRQQHANMRCTCSCYSAVGAPYEEVVRYQRQPADKHRL 234
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L+GP G NELR++L+ F SAVPHTTRS + E+ GR+YH+VSR+ FE+ +
Sbjct 235 IVLVGPSGVGVNELRRQLIGCNPSCFQSAVPHTTRSPKSYEMDGREYHYVSRETFESLMY 294
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+ +E GE++ +LYGTS+++V V++ GKIC++ L Q ++ R +LKPY+IFI PPS
Sbjct 295 GHRMLEFGEYKGHLYGTSVNAVLAVLDEGKICVMDLEPQDIQLARTRELKPYVIFIKPPS 354
Query 602 QERLR--ALLAKEGKN------PKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
+R AK + K E+L+E+ E ++ME G +FD IVN +L A
Sbjct 355 MSSMRHSRRNAKIITDYFVDMKFKDEDLQEMEELAQKMESQFGQFFDHVIVNDNLQDARA 414
Query 654 ELLRLINKLDTEPQWVPSTWL 674
+LL I K + E QWVP W+
Sbjct 415 QLLSAIQKAEEELQWVPEAWV 435
>sp|P49697|EM55_TAKRU 55 kDa erythrocyte membrane protein OS=Takifugu
rubripes OX=31033 GN=mpp1 PE=3 SV=1
Length=467
Score = 417 bits (1071), Expect = 1e-138, Method: Composition-based stats.
Identities = 140/473 (30%), Positives = 249/473 (53%), Gaps = 32/473 (7%)
Query 208 LTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYES-----IGQYGGETVKIVRIEKA 262
+ L+ +++ LL + MQ V+ + I ++ V EK
Sbjct 20 VRTALSDLYLEQLLQNKPTDKQAAMQTYENKGAEVFSNGSAGHINGAELSRMREVAFEKN 79
Query 263 RDIPLGATVR-NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ PLG T++ N+ ++RI+ GG + G LHEGDE+ EING + + V+++ +L
Sbjct 80 QSEPLGVTLKLNDKQRCSVARILHGGMIHRQGSLHEGDEIAEINGKSVANQTVDQLQKIL 139
Query 322 SDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHV 381
+ +G +T +IP Q + P + ++++ FDYDP+ D +PC+E GL FQ GDI+ +
Sbjct 140 KETNGVVTMKIIPRPQSRSKPCE---MYMRGQFDYDPAMDDLIPCKEAGLKFQTGDIIQI 196
Query 382 ISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKN 441
I+++DPNWWQ E + AGL+P Q+ R A K + G C+
Sbjct 197 INKQDPNWWQGRVE--NNAANFAGLIPSPELQEWRAA-------SKSKAREGSQSCSPFG 247
Query 442 KKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMN 501
KKK+ K Y A + +D ++++YEE+ PA +++ ++LIG G+ ++ L+
Sbjct 248 KKKKCKDKYLAKHSSIFDQLDVISYEEVV--RLPAFKRKTLVLIGAPGVGRRHIKNVLLT 305
Query 502 KEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSID 561
K ++F+ VPHTTR +R + G +Y F+S +A I+A + +E+G F+ ++GT +
Sbjct 306 KYPEKFSYPVPHTTRPQRKGDANGEEYFFISNEAMTKCISANELLEYGSFQGYMFGTITE 365
Query 562 SVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEEL 621
+++++ KI LL + Q++K LR +D P ++FIAP + E L
Sbjct 366 TIQKIHEQDKIALLDVEPQTMKVLRTADFGPLMVFIAPTD------------TAAQTENL 413
Query 622 REIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWL 674
+ I +++ + YFD +VN+D++++ + + + T PQWVP +W+
Sbjct 414 QMIQKESETILNTYRQYFDVVLVNNDVNESVKIVEEALEHATTTPQWVPVSWV 466
>sp|Q92796|DLG3_HUMAN Disks large homolog 3 OS=Homo sapiens OX=9606
GN=DLG3 PE=1 SV=2
Length=817
Score = 415 bits (1067), Expect = 2e-133, Method: Composition-based stats.
Identities = 137/469 (29%), Positives = 219/469 (47%), Gaps = 44/469 (9%)
Query 232 MQLEPITDERVYE---SIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGA 288
Q+ P + + + E KI+ + + + + + + +S I+ GG
Sbjct 360 PQVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGP 419
Query 289 AEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ----------- 337
A+ SG L GD +L +NG+ +R + L ++T V +
Sbjct 420 ADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHD 479
Query 338 --------------IKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVIS 383
+++ ++V+A FDYD + D +P + GLSF GDILHVI+
Sbjct 480 LREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQ--GLSFSYGDILHVIN 537
Query 384 QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKK 443
D WWQA G++P K +++E + ++ K ++G + +
Sbjct 538 ASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKE--RARLKTVKFHARTGMIESNRDFPG 595
Query 444 KRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKE 503
Y KN + IL+YE ++ Q + RP+I++GP ++ + L+++
Sbjct 596 LSDD--YYGAKNLKGQEDAILSYEPVT--RQEIHYARPVIILGPM---KDRVNDDLISEF 648
Query 504 KDRFASAVPHTTRSRRDQEVAGRDYHFV-SRQAFEADIAAGKFIEHGEFEKNLYGTSIDS 562
+F S VPHTTR RRD EV G+DYHFV SR+ E DI KFIE G+F NLYGTSI S
Sbjct 649 PHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNLYGTSIQS 708
Query 563 VRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELR 622
VR V GK C+L + ++K L+ + L P IFI P S E L + + E+
Sbjct 709 VRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEM----NRRQTYEQAN 764
Query 623 EIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPS 671
+I +K ++EQ G YF + L++ Y ++ ++I WVPS
Sbjct 765 KIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPS 813
Score = 66.2 bits (160), Expect = 6e-10, Method: Composition-based stats.
Identities = 24/103 (23%), Positives = 43/103 (42%), Gaps = 9/103 (9%)
Query 238 TDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD--------SVIISRIVKGGAA 289
R+ Q ET+ V + K LG ++ + S+ I++I++GGAA
Sbjct 208 PVVRLVVRRRQPPPETIMEVNLLKG-PKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAA 266
Query 290 EKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+K G L GD +L +N ++ E L + + +
Sbjct 267 QKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKV 309
Score = 53.5 bits (127), Expect = 5e-06, Method: Composition-based stats.
Identities = 15/77 (19%), Positives = 28/77 (36%), Gaps = 6/77 (8%)
Query 256 IVRIEKARDIPLGATVR------NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
IV + + + I++I+ GGAA G L D VL +N +++
Sbjct 132 IVLERGNSGLGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDV 191
Query 310 RGKDVNEVFDLLSDMHG 326
+ + L +
Sbjct 192 SEVVHSRAVEALKEAGP 208
>sp|Q62936|DLG3_RAT Disks large homolog 3 OS=Rattus norvegicus
OX=10116 GN=Dlg3 PE=1 SV=1
Length=849
Score = 415 bits (1066), Expect = 5e-133, Method: Composition-based stats.
Identities = 138/479 (29%), Positives = 220/479 (46%), Gaps = 50/479 (10%)
Query 232 MQLEPITDERVYE---SIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGA 288
Q+ P + + + E KI+ + + + + + + +S I+ GG
Sbjct 378 PQVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGP 437
Query 289 AEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ----------- 337
A+ SG L GD +L +NG+ +R + L ++T V +
Sbjct 438 ADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHD 497
Query 338 --------------IKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVIS 383
+++ ++V+A FDYD + D +P + GLSF GDILHVI+
Sbjct 498 LREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQ--GLSFSYGDILHVIN 555
Query 384 QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQRE----------AMKQTIEEDKEPEKSG 433
D WWQA G++P K +++E A IE +++
Sbjct 556 ASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLS 615
Query 434 KLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQN 493
+ KN K ++ + + IL+YE ++ Q + RP+I++GP ++
Sbjct 616 DDYYGAKNLKGVTSNTSDSESSSKGQEDAILSYEPVT--RQEIHYARPVIILGPM---KD 670
Query 494 ELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFV-SRQAFEADIAAGKFIEHGEFE 552
+ L+++ +F S VPHTTR RRD EV G+DYHFV SR+ E DI KFIE G+F
Sbjct 671 RVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFN 730
Query 553 KNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKE 612
NLYGTSI SVR V GK C+L + ++K L+ + L P IFI P S E L +
Sbjct 731 DNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEM---- 786
Query 613 GKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPS 671
+ E+ +I +K ++EQ G YF + L++ Y ++ ++I WVPS
Sbjct 787 NRRQTYEQANKIFDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPS 845
Score = 66.2 bits (160), Expect = 6e-10, Method: Composition-based stats.
Identities = 24/103 (23%), Positives = 43/103 (42%), Gaps = 9/103 (9%)
Query 238 TDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD--------SVIISRIVKGGAA 289
R+ Q ET+ V + K LG ++ + S+ I++I++GGAA
Sbjct 226 PVVRLVVRRRQPPPETIMEVNLLKG-PKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAA 284
Query 290 EKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+K G L GD +L +N ++ E L + + +
Sbjct 285 QKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKV 327
Score = 55.8 bits (133), Expect = 1e-06, Method: Composition-based stats.
Identities = 19/112 (17%), Positives = 39/112 (35%), Gaps = 10/112 (9%)
Query 225 DKVAEQEMQLEPITDERVYESIGQYGGETV----KIVRIEKARDIPLGATVR------NE 274
D + + E + S+ G + + +IV + +
Sbjct 115 DWYEQASPAPLLVNPEALEPSLSVNGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPD 174
Query 275 MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
+ I++I+ GGAA G L D VL +N +++ + + L +
Sbjct 175 DPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGP 226
>sp|P70175|DLG3_MOUSE Disks large homolog 3 OS=Mus musculus OX=10090
GN=Dlg3 PE=1 SV=1
Length=849
Score = 415 bits (1066), Expect = 5e-133, Method: Composition-based stats.
Identities = 138/479 (29%), Positives = 220/479 (46%), Gaps = 50/479 (10%)
Query 232 MQLEPITDERVYE---SIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGA 288
Q+ P + + + E KI+ + + + + + + +S I+ GG
Sbjct 378 PQVPPTRYSPIPRHMLAEEDFTREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGP 437
Query 289 AEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ----------- 337
A+ SG L GD +L +NG+ +R + L ++T V +
Sbjct 438 ADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRFESKIHD 497
Query 338 --------------IKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVIS 383
+++ ++V+A FDYD + D +P + GLSF GDILHVI+
Sbjct 498 LREQMMNSSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQ--GLSFSYGDILHVIN 555
Query 384 QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQRE----------AMKQTIEEDKEPEKSG 433
D WWQA G++P K +++E A IE +++
Sbjct 556 ASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFPGLS 615
Query 434 KLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQN 493
+ KN K ++ + + IL+YE ++ Q + RP+I++GP ++
Sbjct 616 DDYYGAKNLKGVTSNTSDSESSSKGQEDAILSYEPVT--RQEIHYARPVIILGPM---KD 670
Query 494 ELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFV-SRQAFEADIAAGKFIEHGEFE 552
+ L+++ +F S VPHTTR RRD EV G+DYHFV SR+ E DI KFIE G+F
Sbjct 671 RVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFN 730
Query 553 KNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKE 612
NLYGTSI SVR V GK C+L + ++K L+ + L P IFI P S E L +
Sbjct 731 DNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKPKSIEALMEM---- 786
Query 613 GKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPS 671
+ E+ +I +K ++EQ G YF + L++ Y ++ ++I WVPS
Sbjct 787 NRRQTYEQANKIFDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQIIEDQSGHYIWVPS 845
Score = 66.2 bits (160), Expect = 6e-10, Method: Composition-based stats.
Identities = 24/103 (23%), Positives = 43/103 (42%), Gaps = 9/103 (9%)
Query 238 TDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD--------SVIISRIVKGGAA 289
R+ Q ET+ V + K LG ++ + S+ I++I++GGAA
Sbjct 226 PVVRLVVRRRQPPPETIMEVNLLKG-PKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAA 284
Query 290 EKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+K G L GD +L +N ++ E L + + +
Sbjct 285 QKDGRLQIGDRLLAVNNTNLQDVRHEEAVASLKNTSDMVYLKV 327
Score = 55.8 bits (133), Expect = 1e-06, Method: Composition-based stats.
Identities = 19/112 (17%), Positives = 39/112 (35%), Gaps = 10/112 (9%)
Query 225 DKVAEQEMQLEPITDERVYESIGQYGGETV----KIVRIEKARDIPLGATVR------NE 274
D + + E + S+ G + + +IV + +
Sbjct 115 DWYEQASPAPLLVNPEALEPSLSVNGSDGMFKYEEIVLERGNSGLGFSIAGGIDNPHVPD 174
Query 275 MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
+ I++I+ GGAA G L D VL +N +++ + + L +
Sbjct 175 DPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGP 226
>sp|Q15700|DLG2_HUMAN Disks large homolog 2 OS=Homo sapiens OX=9606
GN=DLG2 PE=1 SV=3
Length=870
Score = 414 bits (1064), Expect = 1e-132, Method: Composition-based stats.
Identities = 152/537 (28%), Positives = 247/537 (46%), Gaps = 56/537 (10%)
Query 178 PPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQ---ALLLAHDKVAEQEMQL 234
PP P+ S L + + + + + LL+ P+ LL + + +
Sbjct 343 PPEPVYSTVNKLCDKPAS--PRHYSPVECDKSFLLSAPYSHYHLGLLPDSEMTSHSQHST 400
Query 235 EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGL 294
+ GE K+V + + + + + + +S I+ GG A+ SG
Sbjct 401 ATRQPSMTLQRAVSLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGE 460
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI---------------- 338
L GD++L +NGI++RG + L T+T + +
Sbjct 461 LQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMM 520
Query 339 ---------KPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNW 389
++ ++V+A FDYD S D +P + GLSF+ GDILHVI+ D W
Sbjct 521 NHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEW 578
Query 390 WQAYREGDEDNQPLAGLVPGKSFQQQRE-AMKQTIEEDKEPE------------KSGKLW 436
WQA R E + G++P K +++E A +T++ + +P K ++
Sbjct 579 WQARRVMLEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVIDSKGSFNDKRKKSFIF 638
Query 437 CAKKNKKKRKKVLYNANKNDDYDNEE-ILTYEEMSLYHQPANRKRPIILIGPQNCGQNEL 495
K K K+ + + E+ IL+YE ++ Q N RP+I++GP ++ +
Sbjct 639 SRKFPFYKNKEQSEQETSDPERGQEDLILSYEPVT--RQEINYTRPVIILGPM---KDRI 693
Query 496 RQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFV-SRQAFEADIAAGKFIEHGEFEKN 554
L+++ D+F S VPHTTR +RD EV GRDYHFV SR+ E DI KFIE G++ N
Sbjct 694 NDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDN 753
Query 555 LYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGK 614
LYGTS+ SVR V GK C+L + ++K L+ + L P IFI P S E L + K
Sbjct 754 LYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPRSLEPLMEM----NK 809
Query 615 NPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPS 671
E+ ++ ++ ++EQ G YF + L+ Y + +I + W+PS
Sbjct 810 RLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPS 866
Score = 64.7 bits (156), Expect = 2e-09, Method: Composition-based stats.
Identities = 19/83 (23%), Positives = 38/83 (46%), Gaps = 4/83 (5%)
Query 254 VKIVRIEKARDIPLGATVRNE----MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+K+ + K + V N+ +S+ +++I+ GGAA+K G L GD +L +N +
Sbjct 194 IKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSL 253
Query 310 RGKDVNEVFDLLSDMHGTLTFVL 332
E +L + + +
Sbjct 254 EEVTHEEAVAILKNTSEVVYLKV 276
Score = 64.7 bits (156), Expect = 2e-09, Method: Composition-based stats.
Identities = 24/161 (15%), Positives = 57/161 (35%), Gaps = 18/161 (11%)
Query 195 TVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQE---MQLEPIT--------DERVY 243
++ + H G EL + + ++ + H V + ++ P D Y
Sbjct 28 SLPRLTHEVRGPELVHV-SEKNLSQIENVHGYVLQSHISPLKASPAPIIVNTDTLDTIPY 86
Query 244 ESIGQYGGETVKIVRIEKARDIPLGATVR------NEMDSVIISRIVKGGAAEKSGLLHE 297
+ + E +I + + + I++I+ GGAA + G L
Sbjct 87 VNGTEIEYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRV 146
Query 298 GDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
D +L +N +++ ++ + L + + + + I
Sbjct 147 NDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPI 187
>sp|Q91XM9|DLG2_MOUSE Disks large homolog 2 OS=Mus musculus OX=10090
GN=Dlg2 PE=1 SV=2
Length=852
Score = 412 bits (1058), Expect = 1e-131, Method: Composition-based stats.
Identities = 150/524 (29%), Positives = 240/524 (46%), Gaps = 48/524 (9%)
Query 178 PPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQ---ALLLAHDKVAEQEMQL 234
PP P+ S L + + + + + LL+TP+ LL D + +
Sbjct 343 PPEPVYSTVNKLCDKPAS--PRHYSPVECDKSFLLSTPYPHYHLGLLPDSDMTSHSQHST 400
Query 235 EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGL 294
+ GE K+V + + + + + + +S I+ GG A+ SG
Sbjct 401 ATRQPSVTLQRAISLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGE 460
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI---------------- 338
L GD++L +NGI++RG + L T+T + +
Sbjct 461 LQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMM 520
Query 339 ---------KPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNW 389
++ ++V+A FDYD S D +P + GLSF+ GDILHVI+ D W
Sbjct 521 NHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEW 578
Query 390 WQAYREGDEDNQPLAGLVPGKSFQQQRE-AMKQTIEEDKEPEKSGKLWCAKKNKKKRKKV 448
WQA R + + G++P K +++E A +T++ + +P K
Sbjct 579 WQARRVTLDGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVI-----DSKGDIPGLGD 633
Query 449 LYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFA 508
K + IL+YE ++ Q N RP+I++GP ++ + L+++ D+F
Sbjct 634 DGYGTKTLRGQEDLILSYEPVT--RQEINYTRPVIILGPM---KDRINDDLISEFPDKFG 688
Query 509 SAVPHTTRSRRDQEVAGRDYHFV-SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVI 567
S VPHTTR +RD EV GRDYHFV SR+ E DI KFIE G++ NLYGTS+ SVR V
Sbjct 689 SCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVA 748
Query 568 NSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEK 627
GK C+L + ++K L+ + L P IFI P S E L + K E+ ++ ++
Sbjct 749 ERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEM----NKRLTEEQAKKTYDR 804
Query 628 TREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPS 671
++EQ G YF + L+ Y + +I + W+PS
Sbjct 805 AIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPS 848
Score = 65.1 bits (157), Expect = 2e-09, Method: Composition-based stats.
Identities = 19/83 (23%), Positives = 38/83 (46%), Gaps = 4/83 (5%)
Query 254 VKIVRIEKARDIPLGATVRNE----MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+K+ + K + V N+ +S+ +++I+ GGAA+K G L GD +L +N +
Sbjct 194 IKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSL 253
Query 310 RGKDVNEVFDLLSDMHGTLTFVL 332
E +L + + +
Sbjct 254 EEVTHEEAVAILKNTSDVVYLKV 276
Score = 65.1 bits (157), Expect = 2e-09, Method: Composition-based stats.
Identities = 24/161 (15%), Positives = 57/161 (35%), Gaps = 18/161 (11%)
Query 195 TVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQE---MQLEPIT--------DERVY 243
++ + H G EL + + ++ + H V + ++ P D Y
Sbjct 28 SLPRLTHEVRGPELVHV-SEKNLSQIENVHGYVLQSHISPLKASPAPIIVNTDTLDTIPY 86
Query 244 ESIGQYGGETVKIVRIEKARDIPLGATVR------NEMDSVIISRIVKGGAAEKSGLLHE 297
+ + E +I + + + I++I+ GGAA + G L
Sbjct 87 VNGTEIEYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRV 146
Query 298 GDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
D +L +N +++ ++ + L + + + + I
Sbjct 147 NDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPI 187
>sp|Q63622|DLG2_RAT Disks large homolog 2 OS=Rattus norvegicus
OX=10116 GN=Dlg2 PE=1 SV=1
Length=852
Score = 410 bits (1054), Expect = 4e-131, Method: Composition-based stats.
Identities = 150/524 (29%), Positives = 240/524 (46%), Gaps = 48/524 (9%)
Query 178 PPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQ---ALLLAHDKVAEQEMQL 234
PP P+ S L + + + + + LL+TP+ LL D + +
Sbjct 343 PPEPVYSTVNKLCDKPAS--PRHYSPVECDKSFLLSTPYPHYHLGLLPDSDMTSHSQHST 400
Query 235 EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGL 294
+ GE K+V + + + + + + +S I+ GG A+ SG
Sbjct 401 ATRQPSVTLQRAISLEGEPRKVVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGE 460
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI---------------- 338
L GD++L +NGI++RG + L T+T + +
Sbjct 461 LQRGDQILSVNGIDLRGASHEQAAAALKGAGQTVTIIAQYQPEDYARFEAKIHDLREQMM 520
Query 339 ---------KPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNW 389
++ ++V+A FDYD S D +P + GLSF+ GDILHVI+ D W
Sbjct 521 NHSMSSGSGSLRTNQKRSLYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEW 578
Query 390 WQAYREGDEDNQPLAGLVPGKSFQQQRE-AMKQTIEEDKEPEKSGKLWCAKKNKKKRKKV 448
WQA R + + G++P K +++E A +T++ + +P K
Sbjct 579 WQARRVILDGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGVI-----DSKGDIPGLGD 633
Query 449 LYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFA 508
K + IL+YE ++ Q N RP+I++GP ++ + L+++ D+F
Sbjct 634 DGYGTKTLRGQEDLILSYEPVT--RQEINYTRPVIILGPM---KDRINDDLISEFPDKFG 688
Query 509 SAVPHTTRSRRDQEVAGRDYHFV-SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVI 567
S VPHTTR +RD EV GRDYHFV SR+ E DI KFIE G++ NLYGTS+ SVR V
Sbjct 689 SCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVRFVA 748
Query 568 NSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEK 627
GK C+L + ++K L+ + L P IFI P S E L + K E+ ++ ++
Sbjct 749 ERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSLEPLMEM----NKRLTEEQAKKTYDR 804
Query 628 TREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPS 671
++EQ G YF + L+ Y + +I + W+PS
Sbjct 805 AIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIPS 848
Score = 65.1 bits (157), Expect = 2e-09, Method: Composition-based stats.
Identities = 19/83 (23%), Positives = 38/83 (46%), Gaps = 4/83 (5%)
Query 254 VKIVRIEKARDIPLGATVRNE----MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+K+ + K + V N+ +S+ +++I+ GGAA+K G L GD +L +N +
Sbjct 194 IKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSL 253
Query 310 RGKDVNEVFDLLSDMHGTLTFVL 332
E +L + + +
Sbjct 254 EEVTHEEAVAILKNTSDVVYLKV 276
Score = 64.7 bits (156), Expect = 2e-09, Method: Composition-based stats.
Identities = 24/161 (15%), Positives = 57/161 (35%), Gaps = 18/161 (11%)
Query 195 TVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQE---MQLEPIT--------DERVY 243
++ + H G EL + + ++ + H V + ++ P D Y
Sbjct 28 SLPRLTHEVRGPELVHV-SEKNLSQIENVHGYVLQSHISPLKASPAPIIVNTDTLDTIPY 86
Query 244 ESIGQYGGETVKIVRIEKARDIPLGATVR------NEMDSVIISRIVKGGAAEKSGLLHE 297
+ + E +I + + + I++I+ GGAA + G L
Sbjct 87 VNGTEIEYEFEEITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRV 146
Query 298 GDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
D +L +N +++ ++ + L + + + + I
Sbjct 147 NDCILRVNEVDVSEVSHSKAVEALKEAGSIVRLYVRRRRPI 187
>sp|Q5PYH7|DLG2_DANRE Disks large homolog 2 OS=Danio rerio OX=7955
GN=dlg2 PE=2 SV=1
Length=881
Score = 400 bits (1028), Expect = 5e-127, Method: Composition-based stats.
Identities = 150/562 (27%), Positives = 255/562 (45%), Gaps = 68/562 (12%)
Query 163 FKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLN--TPHIQAL 220
K+ +V+++ P + + + ++ + + E + L +P +
Sbjct 331 LKVGKPTSVYLSDPYGPPDITHS---FSPAMENHISSPGNNGTLEYKSSLPPISPGRYSP 387
Query 221 LLAHDKVAEQEMQLEPITDERV---YESIGQYGGETVKIVRIEKARDIPLGATVRNEMDS 277
L H + E+++ P DE ++S E KIV + + + + +
Sbjct 388 LPKH-LLGEEDINRNPSLDEMEGHRFDSQHFQLREPRKIVLHKGSTGLGFNIVGGEDGEG 446
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
+ +S I+ GG A+ SG L GD++L +NGI++RG + L T+T + +
Sbjct 447 IFVSFILAGGPADLSGELRRGDQILSVNGIDLRGATHEQAAAALKGAGQTVTIIAQYRPE 506
Query 338 I-------------------------KPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLS 372
++ ++V+A FDY+ + D +P + GLS
Sbjct 507 EYGRFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSLYVRALFDYERAKDSGLPSQ--GLS 564
Query 373 FQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQRE-AMKQTIEEDKEPE- 430
F+ GDILHVI+ D WWQA R E + G++P K +++E A +T++ + +P
Sbjct 565 FRYGDILHVINASDDEWWQARRVTPEGDSEEMGVIPSKRRVERKERARLKTVKFNAKPGS 624
Query 431 -----------KSGKLWCAKKNKKKRKKVLYNANKNDDYDNEE-ILTYEEMSLYHQPANR 478
+ ++ K K K + + EE IL+YE + Q N
Sbjct 625 LDSKGSFSEKRRKNFIFSRKFPFYKNKDADEQDGSDSERSQEELILSYEPV--IRQEINY 682
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVP--------HTTRSRRDQEVAGRDYHF 530
RP+I++GP ++ + L+++ D+F S VP TTR +RD EV GRDYHF
Sbjct 683 ARPVIILGPM---KDRINDDLISEFPDKFGSCVPPANSSDQEDTTRPKRDYEVDGRDYHF 739
Query 531 V-SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD 589
+ SR+ E DI KFIE G++ NLYGTS+ SV+ V GK C+L + ++K L+ +
Sbjct 740 MASREQMEKDIQEHKFIEAGQYNDNLYGTSVQSVKYVAERGKHCILDVSGNAIKRLQVAQ 799
Query 590 LKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLD 649
L P IFI P S E L + K E+ ++ ++ ++EQ G YF + L+
Sbjct 800 LYPIAIFIKPRSIESLMEM----NKRLTEEQAKKTYDRAMKLEQEFGEYFTALVQGDTLE 855
Query 650 KAYQELLRLINKLDTEPQWVPS 671
Y + +I + W+PS
Sbjct 856 DIYNQCKMVIEEQSGPYIWIPS 877
Score = 64.7 bits (156), Expect = 2e-09, Method: Composition-based stats.
Identities = 19/83 (23%), Positives = 39/83 (47%), Gaps = 4/83 (5%)
Query 254 VKIVRIEKARDIPLGATVRNE----MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+K+++ K + V N+ +S+ +++I+ GGAA+K G L GD +L +N +
Sbjct 251 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYTL 310
Query 310 RGKDVNEVFDLLSDMHGTLTFVL 332
E +L + + +
Sbjct 311 EEVTHEEAVAILKNTSDVVYLKV 333
Score = 59.3 bits (142), Expect = 1e-07, Method: Composition-based stats.
Identities = 24/188 (13%), Positives = 61/188 (32%), Gaps = 14/188 (7%)
Query 167 NAITVHMNKASPPFPLISNAQDLAQEV----QTVLKPVHHKEGQELTALLNTPHIQALLL 222
++ + + P + L EV + + E + + ++ HI L
Sbjct 67 DSPHSYRYQDDDSPPPEHSFPRLTNEVRAPELVHVSEKNLSEIENVHGYVSHSHISPLKA 126
Query 223 AHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVR------NEMD 276
+ + LE + E ++ T++ + +
Sbjct 127 SPAPIIVNTDTLESVPYVNGTEIEYEFEEITLE----RGNSGLGFSIAGGTDNPHIGDDP 182
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQ 336
+ I++I+ GGAA + G L D +L +N ++ ++ + L + + +
Sbjct 183 GIFITKIIPGGAAAEDGRLRVNDCILRVNESDVSEVSHSKAVEALKAAGSIVRLYVRRRR 242
Query 337 QIKPPPAK 344
+ +
Sbjct 243 PMLETVTE 250
>sp|Q5PYH5|DLG1L_DANRE Discs large homolog 1-like protein OS=Danio
rerio OX=7955 GN=dlg1l PE=2 SV=1
Length=827
Score = 397 bits (1020), Expect = 2e-126, Method: Composition-based stats.
Identities = 134/469 (29%), Positives = 224/469 (48%), Gaps = 56/469 (12%)
Query 234 LEPITDERVYESIGQYGG------ETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGG 287
L P+ R + G E K+V + + + + IS I+ GG
Sbjct 376 LPPVHSGRFSPTPKTTVGDDDVTREPRKVVLHRGTTGLGFNIVGGEDGEGIFISFILAGG 435
Query 288 AAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ---------- 337
A+ G L +GD ++ +NGI++RG + L + T+T V +
Sbjct 436 PADLCGELRKGDRLVSVNGIDLRGATHEQAAAALKNAGQTVTIVAQYRPEEYSRFEAKIH 495
Query 338 ---------------IKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVI 382
+++ ++V+A FDYD + D +P + GL+F+ GDILHV+
Sbjct 496 DLREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQ--GLNFKFGDILHVV 553
Query 383 SQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQRE-AMKQTIEEDKEPEKSGKLWCAKKN 441
+ D WWQA + + G++P K +++E A +T++ + K+
Sbjct 554 NASDDEWWQARQVTAQGEVEEMGVIPSKRRVEKKERARLKTVKFN------------SKS 601
Query 442 KKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMN 501
++K +K E +L+YE +S Q N RP+I++GP ++ + L++
Sbjct 602 REKGDNPDDMLSKGQSGQEEYVLSYEPVS--QQEVNYSRPVIILGPM---KDRVNDDLIS 656
Query 502 KEKDRFASAVPHTTRSRRDQEVAGRDYHFV-SRQAFEADIAAGKFIEHGEFEKNLYGTSI 560
+ D+F S VPHTTR +RD EV GRDYHFV SR+ E DI KFIE G++ +LYGTS+
Sbjct 657 EFPDKFGSCVPHTTRPKRDYEVDGRDYHFVVSREQMERDIQEHKFIEAGQYNSHLYGTSV 716
Query 561 DSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEE 620
SVR+V GK C+L + ++K L+ + L P IFI P S E + + K E+
Sbjct 717 QSVREVAEKGKHCILDVSGNAIKRLQVAMLYPIGIFIKPKSVENIMEM----NKRLTEEQ 772
Query 621 LREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWV 669
R+ ++ ++EQ +F + L++ Y ++ ++I + WV
Sbjct 773 GRKTYDRAMKLEQEFMEHFTAIVQGDTLEEIYDQVKQIIEEQSGPYIWV 821
Score = 65.5 bits (158), Expect = 1e-09, Method: Composition-based stats.
Identities = 20/129 (16%), Positives = 44/129 (34%), Gaps = 14/129 (11%)
Query 228 AEQEMQLEPIT--------DERVYESIGQYGGETVKIVRIEKARDIPLGATVR------N 273
+ +Q P D Y + + E +I +
Sbjct 124 SPVSVQANPPPVVVNTESLDSAPYVNGTEADFEYEEITLERGNSGLGFSIAGGTDNPHIG 183
Query 274 EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
E S+ I++++ GGAA + G L D +L +N +++R ++ + L + + +
Sbjct 184 EDPSIFITKVIPGGAAAQDGRLRVNDVILRVNEVDVRDVTHSKAVEALKEAGSLVRLYVR 243
Query 334 PSQQIKPPP 342
+
Sbjct 244 RRKSASEKV 252
Score = 62.4 bits (150), Expect = 1e-08, Method: Composition-based stats.
Identities = 18/83 (22%), Positives = 38/83 (46%), Gaps = 4/83 (5%)
Query 254 VKIVRIEKARDIPLGATVRNE----MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+K+++ K + V N+ +S+ +++I++GGAA K G L GD++L +N +
Sbjct 255 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLLAVNSSCL 314
Query 310 RGKDVNEVFDLLSDMHGTLTFVL 332
L + + +
Sbjct 315 EEVTHEHAVTALKNTPDVVYLKV 337
>sp|Q12959|DLG1_HUMAN Disks large homolog 1 OS=Homo sapiens OX=9606
GN=DLG1 PE=1 SV=2
Length=904
Score = 394 bits (1012), Expect = 2e-124, Method: Composition-based stats.
Identities = 129/456 (28%), Positives = 221/456 (48%), Gaps = 40/456 (9%)
Query 245 SIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEI 304
+ E K+V + + + + + IS I+ GG A+ SG L +GD ++ +
Sbjct 456 GDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISV 515
Query 305 NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ-------------------------IK 339
N +++R + L + +T V +
Sbjct 516 NSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGS 575
Query 340 PPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDED 399
+++ ++V+A FDYD + D +P + GL+F+ GDILHVI+ D WWQA + +
Sbjct 576 LRTSQKRSLYVRALFDYDKTKDSGLPSQ--GLNFKFGDILHVINASDDEWWQARQVTPDG 633
Query 400 NQPLAGLVPGKSFQQQRE-AMKQTIEEDKEPEKSGKL--WCAKKNKKKRKKVLYNANKND 456
G++P K +++E A +T++ + + G++ K K ++ +
Sbjct 634 ESDEVGVIPSKRRVEKKERARLKTVKFNSKTRDKGEIPDDMGSKGLKHVTSNASDSESSY 693
Query 457 DYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTR 516
E +L+YE ++ Q N RP+I++GP ++ + L+++ D+F S VPHTTR
Sbjct 694 RGQEEYVLSYEPVN--QQEVNYTRPVIILGPM---KDRINDDLISEFPDKFGSCVPHTTR 748
Query 517 SRRDQEVAGRDYHFV-SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLL 575
+RD EV GRDYHFV SR+ E DI KFIE G++ +LYGTS+ SVR+V GK C+L
Sbjct 749 PKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCIL 808
Query 576 SLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNN 635
+ ++K L+ + L P IFI P S E + + K E+ R+ E+ ++EQ
Sbjct 809 DVSGNAIKRLQIAQLYPISIFIKPKSMENIMEM----NKRLTEEQARKTFERAMKLEQEF 864
Query 636 GHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPS 671
+F + L+ Y ++ ++I + WVP+
Sbjct 865 TEHFTAIVQGDTLEDIYNQVKQIIEEQSGSYIWVPA 900
Score = 64.7 bits (156), Expect = 2e-09, Method: Composition-based stats.
Identities = 19/83 (23%), Positives = 40/83 (48%), Gaps = 4/83 (5%)
Query 254 VKIVRIEKARDIPLGATVRNE----MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+K+++ K + V N+ +S+ +++I++GGAA K G L GD++L +N + +
Sbjct 320 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCL 379
Query 310 RGKDVNEVFDLLSDMHGTLTFVL 332
E L + + +
Sbjct 380 EEVTHEEAVTALKNTSDFVYLKV 402
Score = 61.2 bits (147), Expect = 2e-08, Method: Composition-based stats.
Identities = 57/326 (17%), Positives = 105/326 (32%), Gaps = 42/326 (13%)
Query 48 MPIRRSAQ------LERIRQ---QQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTG 98
MP+R+ LE R Q ED + R E N L + + T
Sbjct 1 MPVRKQDTQRALHLLEEYRSKLSQTEDRQLRSSIERVINIFQSNLFQALIDIQEFYEVTL 60
Query 99 IDNPMFDTEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKD 158
+DNP P V EI L SS T+ +S ++ + +D
Sbjct 61 LDNPKCIDRSKP--SEPIQPVNTWEISSLPSS------TVTSETLPSSLSPSVEKYRYQD 112
Query 159 FQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELT---ALLNTP 215
+ H + + P L+ ++ E++ V V H + A+L +P
Sbjct 113 EDTPPQEHISPQITNEVIGP--ELVHVSEKNLSEIENVHGFVSHSHISPIKPTEAVLPSP 170
Query 216 HIQALLLAHDKVAEQEMQLEPITDERVYE--------------SIGQYGGETVKIVRIEK 261
++ AE + L I + E +I
Sbjct 171 PTVPVIPVLPVPAENTVILPTIPQANPPPVLVNTDSLETPTYVNGTDADYEYEEITLERG 230
Query 262 ARDIPLGATVR------NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVN 315
+ + S+ I++I+ GGAA + G L D +L +N +++R +
Sbjct 231 NSGLGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHS 290
Query 316 EVFDLLSDMHGTLTFVLIPSQQIKPP 341
+ + L + + + + +
Sbjct 291 KAVEALKEAGSIVRLYVKRRKPVSEK 316
>sp|Q28C55|DLG1_XENTR Disks large homolog 1 OS=Xenopus tropicalis
OX=8364 GN=dlg1 PE=2 SV=1
Length=927
Score = 394 bits (1011), Expect = 4e-124, Method: Composition-based stats.
Identities = 131/495 (26%), Positives = 228/495 (46%), Gaps = 68/495 (14%)
Query 234 LEPITDERVYE-----SIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGA 288
L P E K+V + + + + IS I+ GG
Sbjct 440 LPPSPGRYSPAPKGMLEDDDLTREPRKVVLQRGTTGLGFNIVGGEDGEGIFISFILAGGP 499
Query 289 AEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ----------- 337
A+ SG L +GD ++ +NG++++ + L + T+T V +
Sbjct 500 ADLSGELQKGDRIMSVNGVDLKSATHEQAAAALKNAGQTVTIVAQYRPEEYSRFEAKIHD 559
Query 338 --------------IKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVIS 383
+++ ++V+A FDYD + D +P + GL+F+ GDILHV++
Sbjct 560 LREQMMNSSISSGSGSLRTSQKRSLYVRALFDYDKTKDSGLPSQ--GLNFKFGDILHVVN 617
Query 384 QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQRE-AMKQTIEED-KEPEKSGKLWC--AK 439
D WWQA + + G++P K +++E A +T++ + K G+ + K
Sbjct 618 ASDDEWWQARQVTADGESEEIGVIPSKRRVEKKERARLKTVKFNSKARGDKGQSFNDKRK 677
Query 440 KNKKKRKKVLYNANKNDDYDNEEI----------------------LTYEEMSLYHQPAN 477
KN RK Y + + ++ L+YE ++ Q N
Sbjct 678 KNLFSRKFPFYKNKDQSEMETSDVDQHVTSNASDSESSYRGQEEYVLSYEPVN--QQEVN 735
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFV-SRQAF 536
RP+I++GP ++ + L+++ ++F S VPHTTR +RD E+ GRDYHFV SR+
Sbjct 736 YSRPVIILGPT---KDRVNDDLISEFPEKFGSCVPHTTRPKRDYEIDGRDYHFVTSREQM 792
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
E DI +FIE G++ +LYGTS+ SV++V GK C+L + ++K L+ + L P IF
Sbjct 793 EKDIQDHRFIEAGQYNSHLYGTSVQSVKEVAERGKHCILDVSGNAIKRLQIAQLYPIAIF 852
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I P S E + + K E+ R+ E+ ++EQ +F + L++ Y ++
Sbjct 853 IKPKSVENIIEM----SKRVTEEQGRKTYERAMKLEQEFTEHFTAIVQGDTLEEIYNQIK 908
Query 657 RLINKLDTEPQWVPS 671
++I + + WVP+
Sbjct 909 QIIEEQSSTFIWVPA 923
Score = 63.9 bits (154), Expect = 4e-09, Method: Composition-based stats.
Identities = 19/84 (23%), Positives = 40/84 (48%), Gaps = 4/84 (5%)
Query 253 TVKIVRIEKARDIPLGATVRNE----MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIE 308
+K+V+ K + V N+ +S+ +++I++GGAA K G L GD++L +N +
Sbjct 318 DIKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKLLAVNTVC 377
Query 309 IRGKDVNEVFDLLSDMHGTLTFVL 332
+ + L + + +
Sbjct 378 LEEVSHEDAVTALKNTSDFVNLKV 401
Score = 58.5 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 18/118 (15%), Positives = 41/118 (35%), Gaps = 11/118 (9%)
Query 235 EPITDERVYESIGQYGG-----ETVKIVRIEKARDIPLGATVRNEMD------SVIISRI 283
P+ E+ G E +I + + S+ I++I
Sbjct 198 PPVIVNTDLETPAYVNGTDAEYEYEEITLERGTSGLGFSIAGGTDNPHIGDDISIFITKI 257
Query 284 VKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
+ GGAA + G L D +L +N +++ ++ + L + + + + +
Sbjct 258 ISGGAAAQDGRLRVNDCILRVNEVDVHDVTHSKAVEALKEAGSIVRLYVRRRKPVTEK 315
>sp|Q811D0|DLG1_MOUSE Disks large homolog 1 OS=Mus musculus OX=10090
GN=Dlg1 PE=1 SV=1
Length=905
Score = 392 bits (1007), Expect = 1e-123, Method: Composition-based stats.
Identities = 131/457 (29%), Positives = 220/457 (48%), Gaps = 41/457 (9%)
Query 245 SIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEI 304
+ E K+V + + + + + IS I+ GG A+ SG L +GD ++ +
Sbjct 456 GDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISV 515
Query 305 NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ-------------------------IK 339
N +++R + L + +T V +
Sbjct 516 NSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSVSSGSGS 575
Query 340 PPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDED 399
+++ ++V+A FDYD + D +P + GL+F+ GDILHVI+ D WWQA + +
Sbjct 576 LRTSQKRSLYVRALFDYDKTKDSGLPSQ--GLNFRFGDILHVINASDDEWWQARQVTPDG 633
Query 400 NQPLAGLVPGKSFQQQRE-AMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDD- 457
G++P K +++E A +T++ + + K K V NA+ ++
Sbjct 634 ESDEVGVIPSKRRVEKKERARLKTVKFNSKTRGDKGEIPDDMGSKGLKHVTSNASDSESS 693
Query 458 --YDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTT 515
E +L+YE ++ Q N RP+I++GP ++ + L+++ D+F S VPHTT
Sbjct 694 YRGQEEYVLSYEPVN--QQEVNYTRPVIILGPM---KDRVNDDLISEFPDKFGSCVPHTT 748
Query 516 RSRRDQEVAGRDYHFV-SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICL 574
R +RD EV GRDYHFV SR+ E DI KFIE G++ +LYGTS+ SVR V GK C+
Sbjct 749 RPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVRAVAEKGKHCI 808
Query 575 LSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQN 634
L + ++K L+ + L P IFI P S E + + K E+ R+ E+ ++EQ
Sbjct 809 LDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEM----NKRLTEEQARKTFERAMKLEQE 864
Query 635 NGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPS 671
+F + L+ Y ++ ++I + WVP+
Sbjct 865 FTEHFTAIVQGDTLEDIYNQVKQIIEEQSGPYIWVPA 901
Score = 64.7 bits (156), Expect = 2e-09, Method: Composition-based stats.
Identities = 19/83 (23%), Positives = 40/83 (48%), Gaps = 4/83 (5%)
Query 254 VKIVRIEKARDIPLGATVRNE----MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+K+++ K + V N+ +S+ +++I++GGAA K G L GD++L +N + +
Sbjct 320 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCL 379
Query 310 RGKDVNEVFDLLSDMHGTLTFVL 332
E L + + +
Sbjct 380 EEVTHEEAVTALKNTSDFVYLKV 402
Score = 58.5 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 20/130 (15%), Positives = 41/130 (32%), Gaps = 14/130 (11%)
Query 226 KVAEQEMQLEPITDERVYESI--------GQYGGETVKIVRIEKARDIPLGATVR----- 272
V Q P +S+ E +I +
Sbjct 187 VVLPSAPQANPPPVLVNTDSLETPTYVNGTDADYEYEEITLERGNSGLGFSIAGGTDNPH 246
Query 273 -NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV 331
+ S+ I++I+ GGAA + G L D +L +N ++R ++ + L + +
Sbjct 247 IGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLY 306
Query 332 LIPSQQIKPP 341
+ +
Sbjct 307 VKRRKPASEK 316
>sp|Q62696|DLG1_RAT Disks large homolog 1 OS=Rattus norvegicus
OX=10116 GN=Dlg1 PE=1 SV=1
Length=911
Score = 389 bits (999), Expect = 2e-122, Method: Composition-based stats.
Identities = 131/464 (28%), Positives = 219/464 (47%), Gaps = 48/464 (10%)
Query 245 SIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEI 304
+ E K+V + + + + + IS I+ GG A+ SG L +GD ++ +
Sbjct 455 GDDEITREPRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISV 514
Query 305 NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ-------------------------IK 339
N +++R + L + +T V +
Sbjct 515 NSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLRETMMNSSVSSGSGS 574
Query 340 PPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDED 399
+++ ++V+A FDYD + D +P + GL+F+ GDILHVI+ D WWQA + +
Sbjct 575 LRTSQKRSLYVRALFDYDKTKDSGLPSQ--GLNFKFGDILHVINASDDEWWQARQVTPDG 632
Query 400 NQPLAGLVPGKSFQQQRE-AMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKND-- 456
G++P K +++E A +T++ + + K K V NA+ ++
Sbjct 633 ESDEVGVIPSKRRVEKKERARLKTVKFNSKTRGDKGEIPDDMGSKGLKHVTSNASDSESS 692
Query 457 --------DYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFA 508
E +L+YE ++ Q N RP+I++GP ++ + L+++ D+F
Sbjct 693 YHEYGCSKGGQEEYVLSYEPVN--QQEVNYTRPVIILGPM---KDRVNDDLISEFPDKFG 747
Query 509 SAVPHTTRSRRDQEVAGRDYHFV-SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVI 567
S VPHTTR +RD EV GRDYHFV SR+ E DI KFIE G++ +LYGTS+ SVR V
Sbjct 748 SCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQYNNHLYGTSVQSVRAVA 807
Query 568 NSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEK 627
GK C+L + ++K L+ + L P IFI P S E + + K E+ R+ E+
Sbjct 808 EKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMENIMEM----NKRLTDEQARKTFER 863
Query 628 TREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPS 671
+EQ +F + L+ Y ++ ++I + WVP+
Sbjct 864 AVRLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGPYIWVPA 907
Score = 63.5 bits (153), Expect = 5e-09, Method: Composition-based stats.
Identities = 19/82 (23%), Positives = 39/82 (48%), Gaps = 4/82 (5%)
Query 254 VKIVRIEKARDIPLGATVRNE----MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+K+++ K + V N+ +S+ +++I++GGAA K G L GD++L +N + +
Sbjct 319 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNSVCL 378
Query 310 RGKDVNEVFDLLSDMHGTLTFV 331
E L + +
Sbjct 379 EEVTHEEAVTALKNTSDFVYLK 400
Score = 58.1 bits (139), Expect = 2e-07, Method: Composition-based stats.
Identities = 31/182 (17%), Positives = 60/182 (33%), Gaps = 8/182 (4%)
Query 154 VQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLN 213
V K +H ++ P + + + + P T N
Sbjct 137 VSEKSLSEIENVHGFVSHSHISPIKPTEAVPPSSPIVPVTPALPVPAESPVVLPSTPQAN 196
Query 214 TPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRN 273
P +L+ D + + + YE I G + I D P
Sbjct 197 PP---PVLVNTDSLETPTY-VNGTDADYEYEEITLERGNSGLGFSIAGGTDNP----HIG 248
Query 274 EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
+ S+ I++I+ GGAA + G L D +L +N ++R ++ + L + + +
Sbjct 249 DDSSIFITKIITGGAAAQDGRLRVNDCILRVNEADVRDVTHSKAVEALKEAGSIVRLYVK 308
Query 334 PS 335
Sbjct 309 RR 310
>sp|P31016|DLG4_RAT Disks large homolog 4 OS=Rattus norvegicus
OX=10116 GN=Dlg4 PE=1 SV=1
Length=724
Score = 380 bits (976), Expect = 5e-121, Method: Composition-based stats.
Identities = 126/465 (27%), Positives = 211/465 (45%), Gaps = 63/465 (14%)
Query 233 QLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKS 292
+ P+ + + E E +IV + + + + + IS I+ GG A+ S
Sbjct 293 RYSPVAKDLLGEE--DIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLS 350
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI-------------- 338
G L +GD++L +NG+++R + L + T+T + +
Sbjct 351 GELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQ 410
Query 339 -----------KPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDP 387
+ +++A FDYD + D + LSF+ GD+LHVI D
Sbjct 411 LMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQ--ALSFRFGDVLHVIDAGDE 468
Query 388 NWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKK 447
WWQA R + G +P K ++RE + K W + + R+
Sbjct 469 EWWQARRVHSDSETDDIGFIPSKRRVERREWSRL----------KAKDWGSSSGSQGRE- 517
Query 448 VLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRF 507
+ +L+YE ++ + RPII++GP ++ L+++ D+F
Sbjct 518 -------------DSVLSYETVT--QMEVHYARPIIILGPT---KDRANDDLLSEFPDKF 559
Query 508 ASAVPHTTRSRRDQEVAGRDYHFV-SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQV 566
S VPHTTR +R+ E+ GRDYHFV SR+ E DI A KFIE G++ +LYGTS+ SVR+V
Sbjct 560 GSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREV 619
Query 567 INSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIE 626
GK C+L + +++ L+ + L P IFI P S E + + K E+ R+ +
Sbjct 620 AEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE-INKRITE---EQARKAFD 675
Query 627 KTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPS 671
+ ++EQ F + ++ Y ++ R+I L WVP+
Sbjct 676 RATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA 720
Score = 63.5 bits (153), Expect = 4e-09, Method: Composition-based stats.
Identities = 18/83 (22%), Positives = 41/83 (49%), Gaps = 4/83 (5%)
Query 254 VKIVRIEKARDIPLGATVRNE----MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+K+++ K + V N+ +S+ +++I++GGAA K G L GD++L +N + +
Sbjct 161 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGL 220
Query 310 RGKDVNEVFDLLSDMHGTLTFVL 332
+ L + + + +
Sbjct 221 EDVMHEDAVAALKNTYDVVYLKV 243
Score = 62.0 bits (149), Expect = 1e-08, Method: Composition-based stats.
Identities = 14/89 (16%), Positives = 33/89 (37%), Gaps = 6/89 (7%)
Query 260 EKARDIPLGATVR------NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
+ + S+ I++I+ GGAA + G L D +L +N +++R
Sbjct 70 RGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVT 129
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPP 342
+ + L + + ++ +
Sbjct 130 HSAAVEALKEAGSIVRLYVMRRKPPAEKV 158
>sp|P78352|DLG4_HUMAN Disks large homolog 4 OS=Homo sapiens OX=9606
GN=DLG4 PE=1 SV=3
Length=724
Score = 380 bits (975), Expect = 5e-121, Method: Composition-based stats.
Identities = 126/465 (27%), Positives = 211/465 (45%), Gaps = 63/465 (14%)
Query 233 QLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKS 292
+ P+ + + E E +IV + + + + + IS I+ GG A+ S
Sbjct 293 RYSPVAKDLLGEE--DIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLS 350
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI-------------- 338
G L +GD++L +NG+++R + L + T+T + +
Sbjct 351 GELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQ 410
Query 339 -----------KPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDP 387
+ +++A FDYD + D + LSF+ GD+LHVI D
Sbjct 411 LMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQ--ALSFRFGDVLHVIDASDE 468
Query 388 NWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKK 447
WWQA R + G +P K ++RE + K W + + R+
Sbjct 469 EWWQARRVHSDSETDDIGFIPSKRRVERREWSRL----------KAKDWGSSSGSQGRE- 517
Query 448 VLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRF 507
+ +L+YE ++ + RPII++GP ++ L+++ D+F
Sbjct 518 -------------DSVLSYETVT--QMEVHYARPIIILGPT---KDRANDDLLSEFPDKF 559
Query 508 ASAVPHTTRSRRDQEVAGRDYHFV-SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQV 566
S VPHTTR +R+ E+ GRDYHFV SR+ E DI A KFIE G++ +LYGTS+ SVR+V
Sbjct 560 GSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREV 619
Query 567 INSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIE 626
GK C+L + +++ L+ + L P IFI P S E + + K E+ R+ +
Sbjct 620 AEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE-INKRITE---EQARKAFD 675
Query 627 KTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPS 671
+ ++EQ F + ++ Y ++ R+I L WVP+
Sbjct 676 RATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA 720
Score = 63.5 bits (153), Expect = 4e-09, Method: Composition-based stats.
Identities = 18/83 (22%), Positives = 41/83 (49%), Gaps = 4/83 (5%)
Query 254 VKIVRIEKARDIPLGATVRNE----MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+K+++ K + V N+ +S+ +++I++GGAA K G L GD++L +N + +
Sbjct 161 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGL 220
Query 310 RGKDVNEVFDLLSDMHGTLTFVL 332
+ L + + + +
Sbjct 221 EDVMHEDAVAALKNTYDVVYLKV 243
Score = 62.0 bits (149), Expect = 1e-08, Method: Composition-based stats.
Identities = 14/89 (16%), Positives = 33/89 (37%), Gaps = 6/89 (7%)
Query 260 EKARDIPLGATVR------NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
+ + S+ I++I+ GGAA + G L D +L +N +++R
Sbjct 70 RGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVT 129
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPP 342
+ + L + + ++ +
Sbjct 130 HSAAVEALKEAGSIVRLYVMRRKPPAEKV 158
>sp|Q62108|DLG4_MOUSE Disks large homolog 4 OS=Mus musculus OX=10090
GN=Dlg4 PE=1 SV=1
Length=724
Score = 378 bits (971), Expect = 2e-120, Method: Composition-based stats.
Identities = 126/465 (27%), Positives = 210/465 (45%), Gaps = 63/465 (14%)
Query 233 QLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKS 292
+ P+ + + E E +IV + + + + + IS I+ GG A+ S
Sbjct 293 RYSPVAKDLLGEE--DIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLS 350
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI-------------- 338
G L +GD++L +NG+++R + L + T+T + +
Sbjct 351 GELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQ 410
Query 339 -----------KPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDP 387
+ +++A FDYD + D + LSF GD+LHVI D
Sbjct 411 LMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQ--ALSFHFGDVLHVIDASDE 468
Query 388 NWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKK 447
WWQA R + G +P K ++RE + K W + + R+
Sbjct 469 EWWQARRVHSDSETDDIGFIPSKRRVERREWSRL----------KAKDWGSSSGSQGRE- 517
Query 448 VLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRF 507
+ +L+YE ++ + RPII++GP ++ L+++ D+F
Sbjct 518 -------------DSVLSYETVT--QMEVHYARPIIILGPT---KDRANDDLLSEFPDKF 559
Query 508 ASAVPHTTRSRRDQEVAGRDYHFV-SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQV 566
S VPHTTR +R+ E+ GRDYHFV SR+ E DI A KFIE G++ +LYGTS+ SVR+V
Sbjct 560 GSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREV 619
Query 567 INSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIE 626
GK C+L + +++ L+ + L P IFI P S E + + K E+ R+ +
Sbjct 620 AEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE-INKRITE---EQARKAFD 675
Query 627 KTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPS 671
+ ++EQ F + ++ Y ++ R+I L WVP+
Sbjct 676 RATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA 720
Score = 65.1 bits (157), Expect = 2e-09, Method: Composition-based stats.
Identities = 32/157 (20%), Positives = 69/157 (44%), Gaps = 17/157 (11%)
Query 180 FPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITD 239
P + AQD V + V+ + +E+T + ++AL A V M+ +P +
Sbjct 100 IPGGAAAQDGRLRVNDSILFVNEVDVREVTH---SAAVEALKEAGSIVRLYVMRRKPPAE 156
Query 240 ERVYESIGQYGGETVKIVRIEKARDIPLGATVRNE----MDSVIISRIVKGGAAEKSGLL 295
+ + +K+++ K + V N+ +S+ +++I++GGAA K G L
Sbjct 157 KIIE----------IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRL 206
Query 296 HEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
GD++L +N + + + L + + + +
Sbjct 207 QIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKV 243
Score = 61.6 bits (148), Expect = 2e-08, Method: Composition-based stats.
Identities = 14/88 (16%), Positives = 33/88 (38%), Gaps = 6/88 (7%)
Query 260 EKARDIPLGATVR------NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
+ + S+ I++I+ GGAA + G L D +L +N +++R
Sbjct 70 RGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVT 129
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
+ + L + + ++ +
Sbjct 130 HSAAVEALKEAGSIVRLYVMRRKPPAEK 157
>sp|P31007|DLG1_DROME Disks large 1 tumor suppressor protein OS=Drosophila
melanogaster OX=7227 GN=dlg1 PE=1 SV=2
Length=970
Score = 379 bits (972), Expect = 5e-118, Method: Composition-based stats.
Identities = 128/494 (26%), Positives = 219/494 (44%), Gaps = 67/494 (14%)
Query 234 LEPITDERVYESIGQYGGETVKIVRIEKA-RDIPLGATVRNEMDSVIISRIVKGGAAEKS 292
L + + + + I+K + + + + +S I+ GG A+
Sbjct 484 LAAVPPGTPRAVSTEDITREPRTITIQKGPQGLGFNIVGGEDGQGIYVSFILAGGPADLG 543
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ--------------- 337
L GD++L +N + + E L G +T + +
Sbjct 544 SELKRGDQLLSVNNVNLTHATHEEAAQALKTSGGVVTLLAQYRPEEYNRFEARIQELKQQ 603
Query 338 ---------IKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPN 388
++ ++V+A FDYDP+ D +P R GL F+ GDILHV + D
Sbjct 604 AALGAGGSGTLLRTTQKRSLYVRALFDYDPNRDDGLPSR--GLPFKHGDILHVTNASDDE 661
Query 389 WWQAYREGDEDNQPLAGLVPGKSFQQQR-EAMKQTIEE------DKEPEKSGKLWCAKKN 441
WWQA R ++ G+VP K +++ A ++++ + +K L KKN
Sbjct 662 WWQARRVLGDNEDEQIGIVPSKRRWERKMRARDRSVKFQGHAAANNNLDKQSTLDRKKKN 721
Query 442 KKKRKKVLYNANKNDDYD-----------------------NEEILTYEEMSLYHQPANR 478
+K + ++++ + E +L+YE + N
Sbjct 722 FTFSRKFPFMKSRDEKNEDGSDQEPFMLCYTQDDANAEGASEENVLSYEAVQRLS--INY 779
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVS-RQAFE 537
RP+I++GP ++ + L+++ D+F S VPHTTR +R+ EV GRDYHFVS R+ E
Sbjct 780 TRPVIILGPL---KDRINDDLISEYPDKFGSCVPHTTRPKREYEVDGRDYHFVSSREQME 836
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
DI FIE G++ NLYGTS+ SVR+V GK C+L + ++K L+ + L P +FI
Sbjct 837 RDIQNHLFIEAGQYNDNLYGTSVASVREVAEKGKHCILDVSGNAIKRLQVAQLYPVAVFI 896
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
P S + + + + E+ ++ E+ +MEQ G YF + +++ Y ++
Sbjct 897 KPKSVDSVMEM----NRRMTEEQAKKTYERAIKMEQEFGEYFTGVVQGDTIEEIYSKVKS 952
Query 658 LINKLDTEPQWVPS 671
+I WVPS
Sbjct 953 MIWSQSGPTIWVPS 966
Score = 49.7 bits (117), Expect = 9e-05, Method: Composition-based stats.
Identities = 18/111 (16%), Positives = 39/111 (35%), Gaps = 13/111 (12%)
Query 234 LEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD--------SVIISRIVK 285
G V + + K LG ++ + + +++++
Sbjct 308 TPAAGSAAGDARDSAASGPKVIEIDLVKG-GKGLGFSIAGGIGNQHIPGDNGIYVTKLMD 366
Query 286 GGAAEKSGLLHEGDEVLEI--NGIE--IRGKDVNEVFDLLSDMHGTLTFVL 332
GGAA+ G L GD+++ + NG E + L + +T ++
Sbjct 367 GGAAQVDGRLSIGDKLIAVRTNGSEKNLENVTHELAVATLKSITDKVTLII 417
Score = 38.9 bits (89), Expect = 0.20, Method: Composition-based stats.
Identities = 14/93 (15%), Positives = 30/93 (32%), Gaps = 6/93 (6%)
Query 260 EKARDIPLGATVRNEMD------SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
+ + S+ I++++ GGAA G L D ++ +N + +
Sbjct 221 RGNSGLGFSIAGGTDNPHIGTDTSIYITKLISGGAAAADGRLSINDIIVSVNDVSVVDVP 280
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKET 346
D L + + + PA +
Sbjct 281 HASAVDALKKAGNVVKLHVKRKRGTATTPAAGS 313
>sp|Q6R005|DLG4_DANRE Disks large homolog 4 OS=Danio rerio OX=7955
GN=dlg4 PE=2 SV=1
Length=801
Score = 362 bits (930), Expect = 2e-113, Method: Composition-based stats.
Identities = 125/511 (24%), Positives = 221/511 (43%), Gaps = 76/511 (15%)
Query 193 VQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESI------ 246
V L HH++ N P I + H +++ L P + R
Sbjct 331 VAKTLHQHHHQDA------YNPPDITSSYSPHMDMSDYPQALSPSSPRRYSPIPKGLFLD 384
Query 247 GQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEING 306
E ++V + + + + + IS I+ GGAA+ SG L +GD++L +NG
Sbjct 385 DDISREPRRVVIHRGSTGLGFNIVGGEDGEGIFISFILAGGAADLSGELRKGDQILSVNG 444
Query 307 IEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI------------------------KPPP 342
+++R + L + T+T + +
Sbjct 445 VDLRHATHEQAAAALKNAGQTVTIITQYRPEEYSRFEAKIHDLREQLMNSSLVSAAASLR 504
Query 343 AKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQP 402
+ + ++A FDYD + D + +SF+ GD+L V D WWQA +
Sbjct 505 SGKRSFFIRALFDYDKTADGGFLSQ--AVSFRFGDVLQVFDCSDEEWWQAGKLAPHGELE 562
Query 403 LAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEE 462
G +P K +++E W K + + + DY
Sbjct 563 ETGYIPSKRRVERKE------------------WSRLKTRGREP-----VSGRSDY---- 595
Query 463 ILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQE 522
I++YE ++ + RP+I++GP ++ + L+++ D+F S VPHTTR +R+ E
Sbjct 596 IVSYETVT--QSEVHYARPVIILGPS---KDRVNDDLLSEFPDKFGSCVPHTTRPKREYE 650
Query 523 VAGRDYHFV-SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVIN-SGKICLLSLRTQ 580
+ GRDYHFV SR+ E DI + +FIE G++ +LYGTS+ SVRQV GK C+L +
Sbjct 651 MDGRDYHFVSSREQMEKDIQSHRFIEAGQYNSHLYGTSVQSVRQVAEQQGKHCILDVSAN 710
Query 581 SLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFD 640
+++ L+ + L P IFI P S + + ++K E+ R +++ ++EQ+ F
Sbjct 711 AVRRLQAAQLYPIAIFIRPSSLQNVLN-ISKRLTE---EQARRALDRAVKLEQDFIECFS 766
Query 641 TAIVNSDLDKAYQELLRLINKLDTEPQWVPS 671
+ ++ Y + +I + W+P+
Sbjct 767 AIVEGESFEEIYHHVKSVIEEQSGPYIWIPA 797
Score = 64.7 bits (156), Expect = 2e-09, Method: Composition-based stats.
Identities = 40/250 (16%), Positives = 73/250 (29%), Gaps = 47/250 (19%)
Query 129 SSLKHIQHTLVDSQSQEDISL------LLQLVQNKDFQNAFKIHN--AITVHMNKASPPF 180
+ + QS D LL + Q+ FQ I +TV N+ +
Sbjct 6 EDTERALQAMEACQSAGDEGFRTRAERLLTIFQSDLFQALLDIQEFYELTVFENQTAGRA 65
Query 181 ---------------PLISNAQDLAQEVQTV---LKPVHHKEGQELTALLNTPHIQALLL 222
PL + L+ L H + A H
Sbjct 66 LTPGLKYRYHDEETPPLQHSPAHLSTGKSAEMLHLGDSGHAPIDGIHAYTPQMH------ 119
Query 223 AHDKVAEQEMQLEPITDERVYESIGQYGG-----ETVKIVRIEKARDIPLGATVR----- 272
V+ + L P Y + G E +I +
Sbjct 120 ----VSPAKPVLLPSGHAPYYATSTLMNGMDGDVEYEEITLERGNSGLGFSIAGGTDNPH 175
Query 273 -NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV 331
+ S+ I++I+ GGAA + G L D +L +N +++R + + L + +
Sbjct 176 IGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNDVDVREVTHSFAVEALKEAGPIVRLY 235
Query 332 LIPSQQIKPP 341
++ +
Sbjct 236 VLRHKPSAEK 245
Score = 62.0 bits (149), Expect = 1e-08, Method: Composition-based stats.
Identities = 18/83 (22%), Positives = 40/83 (48%), Gaps = 4/83 (5%)
Query 254 VKIVRIEKARDIPLGATVRNE----MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+K+++ K + V N+ +S+ +++I++GGAA K G L GD++L +N + +
Sbjct 249 LKLIKGPKGLGFSIAGGVGNQHVPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNNMYL 308
Query 310 RGKDVNEVFDLLSDMHGTLTFVL 332
+ L + + +
Sbjct 309 EEVMHEDAVAALKNTGDVVFLRV 331
>sp|G5ECY0|DLG1_CAEEL Disks large homolog 1 OS=Caenorhabditis
elegans OX=6239 GN=dlg-1 PE=1 SV=1
Length=967
Score = 347 bits (891), Expect = 4e-106, Method: Composition-based stats.
Identities = 130/483 (27%), Positives = 225/483 (47%), Gaps = 56/483 (12%)
Query 236 PITDERVYESIGQYGGETVKIVRIEKAR-DIPLGATVRNEMDSVIISRIVKGGAAEKSGL 294
P+ ++ E + V++ K + + + + + IS ++ GG A+ SG
Sbjct 491 PLNTSYSSQAPIAIPLEP-RPVQLVKGQNGLGFNIVGGEDNEPIYISFVLPGGVADLSGN 549
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTL--TFVLIPSQ---------------- 336
+ GD +LE+NG+ +R E + L + + T P +
Sbjct 550 VKTGDVLLEVNGVVLRNATHKEAAEALRNAGNPVYLTLQYRPQEYQIFESKIEKLRNDVI 609
Query 337 -QIKPPPAKETVIHVKAHFDYDPS-DDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
Q + +V+A FDYDPS ++ P R +G F GDILH+I+ D WW A +
Sbjct 610 AQSRMGTLSRKSEYVRALFDYDPSRENSVAPHRSMG--FNYGDILHIINSSDDEWWTARK 667
Query 395 EGDEDNQPLAGLVPGKSFQQQREAMKQ------------------TIEEDKEPEKSGKLW 436
+ + G++P K ++RE +++ T E++ +S +
Sbjct 668 VHENGEETAEGVIPSKKRVEKRERLRRKQVNFNSGSQSLGRNSSTTGLENRRGSRSQLSF 727
Query 437 CAKKNKKKRKKVLYNANKNDDYDNEE-ILTYEEMSLYHQPANRKRPIILIGPQNCGQNEL 495
K K L + N+ EE + +Y+ + Q N RP+I++G ++ +
Sbjct 728 SRKFPFVKSTDRLNDLNEESSNVAEEPVWSYQAVE--QQAINYVRPVIILG---ALKDRI 782
Query 496 RQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNL 555
L+N++ +F+S VPHT+R R+ EV GRDY+FV++ E D+ FIE G+F+ NL
Sbjct 783 NDELVNRDPSKFSSCVPHTSRPPREGEVNGRDYYFVNKHNMEEDVKNNLFIEAGQFQNNL 842
Query 556 YGTSIDSVRQVINSGKICLLSLRTQSLKTLR-NSDLKPYIIFIAPPSQE---RLRALLAK 611
YGTSI SVR V N G+ C+L + +++ L+ N++++P IFI P S + L + LA
Sbjct 843 YGTSIQSVRDVANQGRHCILDVSGNAIRRLQSNANIQPISIFIKPSSAQQILELDSQLAT 902
Query 612 EGKNPKP---EELREIIEKTREMEQNNGHYFDTAIVN-SDLDKAYQELLRLINKLDTEPQ 667
++ + EE + + +EQ G F I N + ++ +I++ P
Sbjct 903 NRQDDRAMSGEEAQAQYSRCHRIEQTFGDLFTQEISNVHSANDVLSKVYSIISRESQTPI 962
Query 668 WVP 670
WVP
Sbjct 963 WVP 965
Score = 57.4 bits (137), Expect = 4e-07, Method: Composition-based stats.
Identities = 15/93 (16%), Positives = 37/93 (40%), Gaps = 9/93 (10%)
Query 252 ETVKIVRIEKARDIPLGATVRNEMD--------SVIISRIVKGGAAEKSGLLHEGDEVLE 303
++ + K LG ++ + +++I++ GAAE G L GD++LE
Sbjct 357 PNTSVIDLVKGA-RGLGFSIAGGQGNEHVKGDTDIYVTKIIEEGAAELDGRLRVGDKILE 415
Query 304 INGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQ 336
++ + ++L + + ++
Sbjct 416 VDHHSLINTTHENAVNVLKNTGNRVRLLIQQGT 448
Score = 52.0 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 15/93 (16%), Positives = 31/93 (33%), Gaps = 6/93 (6%)
Query 256 IVRIEKARDIPLGATVRNEMD------SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
IV + + T + S+ ++ I++GGAA G + + D + +N
Sbjct 203 IVLEKGHTGLGFSITGGMDQPTEDGDTSIYVTNIIEGGAALADGRMRKNDIITAVNNTNC 262
Query 310 RGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPP 342
+ L ++ L + P
Sbjct 263 ENVKHEVAVNALKSSGNVVSLSLKRRKDEAFLP 295
>sp|Q5PYH6|DLG1_DANRE Disks large homolog 1 OS=Danio rerio OX=7955
GN=dlg1 PE=2 SV=2
Length=873
Score = 301 bits (770), Expect = 2e-89, Method: Composition-based stats.
Identities = 110/494 (22%), Positives = 205/494 (41%), Gaps = 84/494 (17%)
Query 215 PHIQALLLAH--DKVAEQEMQLEPITDERVYE---------SIGQYGGETVKIVRIEKAR 263
P + + H + ++ Q +P+T + E KIV
Sbjct 423 PDVTSSYSQHMENHISTQSYLSQPLTPATPSRYSPVSKGMLGDDEITREPRKIVLHRGTT 482
Query 264 DIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD 323
+ + + + IS I+ GG A+ G L +GD ++ +NG+++R + L +
Sbjct 483 GLGFNIVGGEDGEGIFISFILAGGPADLCGELRKGDRIVSVNGVDLRSATHEQAAAALKN 542
Query 324 MHGTLTFVLIPSQQ-------------------------IKPPPAKETVIHVKAHFDYDP 358
T+T + + +++ ++V+A FDYD
Sbjct 543 AGQTVTIIAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRTLYVRALFDYDI 602
Query 359 SDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREA 418
+ + F + ++ A L ++ +
Sbjct 603 TKT---------VKF-----------------------NSKSRDKASL--NDKRRKTLFS 628
Query 419 MKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANR 478
K ++K+ + + ++ + + +L+YE ++ Q +
Sbjct 629 RKFLFSKNKDSGEQDTSDVD----QHVTSNASDSESSFRGQEDYVLSYETVT--QQEVSY 682
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFV-SRQAFE 537
RP+I++GP ++ + L+++ D+F S VPHTTR +RD EV GRDYHFV SR+ E
Sbjct 683 SRPVIILGPM---KDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVNSREQME 739
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
DI KFIE G++ +LYGTS+ SVR+V GK C+L + ++K L+ + L P +FI
Sbjct 740 KDIQDHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQLAQLYPIAVFI 799
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
P S E + + K E+ R+ ++ ++EQ +F + L++ Y ++ +
Sbjct 800 KPKSVENILEM----NKRLMEEQGRKTYDRAMKLEQEFLEHFTAIVQGDTLEEIYNQVKQ 855
Query 658 LINKLDTEPQWVPS 671
+I + WVP
Sbjct 856 IIEEQSGPFIWVPV 869
Score = 65.5 bits (158), Expect = 1e-09, Method: Composition-based stats.
Identities = 21/84 (25%), Positives = 40/84 (48%), Gaps = 4/84 (5%)
Query 253 TVKIVRIEKARDIPLGATVRNE----MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIE 308
VK+V+ K + V N+ +S+ I++I++GGAA K G L GD++L +N +
Sbjct 325 DVKLVKGPKGLGFSIAGGVGNQHIPGDNSIYITKIIEGGAAHKDGRLQIGDKLLAVNAVC 384
Query 309 IRGKDVNEVFDLLSDMHGTLTFVL 332
+ + L + + +
Sbjct 385 LEEVTHEDAVAALKNTPDVVYLKV 408
Score = 63.2 bits (152), Expect = 6e-09, Method: Composition-based stats.
Identities = 27/141 (19%), Positives = 52/141 (37%), Gaps = 13/141 (9%)
Query 207 ELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIP 266
E TA++ P QA A + E + D Y + + E +I +
Sbjct 189 ETTAIIPAPASQA------SPAPVVVNTESL-DSSPYVNGTEADYEYEEITLERGNSGLG 241
Query 267 LGATVR------NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDL 320
E S+ I++I+ GGAA + G L D +L +N +++R + +
Sbjct 242 FSIAGGTDNPHIGEDPSIFITKIIPGGAAAQDGRLRVNDCILRVNDVDVRDVTHSNAVEA 301
Query 321 LSDMHGTLTFVLIPSQQIKPP 341
L + + + + +
Sbjct 302 LKEAGCIVRLYVRRRKPLSEK 322
>sp|Q0HZX1|KGUA_SHESR Guanylate kinase OS=Shewanella sp. (strain
MR-7) OX=60481 GN=gmk PE=3 SV=2
Length=207
Score = 274 bits (701), Expect = 3e-87, Method: Composition-based stats.
Identities = 52/186 (28%), Positives = 83/186 (45%), Gaps = 2/186 (1%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R I+ P G++ L L+ + +V HTTR+ R EV G+ YHFV+ + F+
Sbjct 4 RGNLFIVSAPSGAGKSSLISALLKDKPADMQVSVSHTTRAPRPGEVNGQHYHFVNVEEFK 63
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
A I F E E N YGTS + + G L + Q + ++ + +FI
Sbjct 64 ALIEQNAFFEWAEVFGNYYGTSRHVIEHTLTQGIDVFLDIDWQGAQQVKAVMPEAIGVFI 123
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS++ L L G++ + + + EM ++ +D IVN D D A +L
Sbjct 124 LPPSRDELERRLTGRGQDSQEVIASRMAQAVSEM--SHYKEYDFIIVNDDFDTALADLRA 181
Query 658 LINKLD 663
+I
Sbjct 182 IIRSQR 187
>sp|Q8EJU6|KGUA_SHEON Guanylate kinase OS=Shewanella oneidensis
(strain MR-1) OX=211586 GN=gmk PE=3 SV=1
Length=207
Score = 274 bits (700), Expect = 5e-87, Method: Composition-based stats.
Identities = 53/186 (28%), Positives = 84/186 (45%), Gaps = 2/186 (1%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R I+ P G++ L L+ + +V HTTR+ R E+ G+ YHFV+ + F+
Sbjct 4 RGNLFIVSAPSGAGKSSLISALLKDKPADMQVSVSHTTRAPRPGEINGQHYHFVNVEEFK 63
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
A IA F E E N YGTS + + G L + Q + ++ + +FI
Sbjct 64 ALIAQNAFFEWAEVFGNYYGTSRHVIEHTLTQGIDVFLDIDWQGAQQVKAVMPEAIGVFI 123
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS++ L L G++ K + + EM ++ +D IVN D D A +L
Sbjct 124 LPPSRDELERRLTGRGQDSKDVIDSRMAQAVSEM--SHYKEYDFIIVNDDFDTALADLRA 181
Query 658 LINKLD 663
+I
Sbjct 182 IIRSQR 187
>sp|Q7WZE5|KGUA_SHEVD Guanylate kinase OS=Shewanella violacea
(strain JCM 10179 / CIP 106290 / LMG 19151 / DSS12) OX=637905
GN=gmk PE=3 SV=1
Length=207
Score = 273 bits (699), Expect = 7e-87, Method: Composition-based stats.
Identities = 53/186 (28%), Positives = 85/186 (46%), Gaps = 2/186 (1%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R I+ P G++ L L+ + +V HTTR R EV G+ YHFV+++ F+
Sbjct 4 RGNLFIVSAPSGAGKSSLISALLQDKPADKQVSVSHTTRQPRPGEVNGQHYHFVTKEEFK 63
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
A I F E E N YGTS + Q + G L + Q + ++ + IFI
Sbjct 64 ALITENAFFEWAEVFGNYYGTSRKVIEQTLTDGIDVFLDIDWQGAQQVKKVMPEAIGIFI 123
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS+ L L G++ K + + E+ ++ + +D I+N D D A +L+
Sbjct 124 LPPSRTELEKRLTGRGQDSKEVIASRMAQAASEI--SHYNEYDFIIINDDFDTALADLVA 181
Query 658 LINKLD 663
+I
Sbjct 182 IIRSQR 187
>sp|Q0HE40|KGUA_SHESM Guanylate kinase OS=Shewanella sp. (strain
MR-4) OX=60480 GN=gmk PE=3 SV=1
Length=207
Score = 273 bits (698), Expect = 1e-86, Method: Composition-based stats.
Identities = 51/186 (27%), Positives = 83/186 (45%), Gaps = 2/186 (1%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R I+ P G++ L L+ + +V HTTR+ R EV G+ YHFV+ + F+
Sbjct 4 RGNLFIVSAPSGAGKSSLISALLKDKPADMQVSVSHTTRAPRPGEVNGQHYHFVNVEEFK 63
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
A I F E E N YGTS + + G L + Q + ++ + +FI
Sbjct 64 ALIEQNAFFEWAEVFGNYYGTSRHVIEHTLTQGIDVFLDIDWQGAQQVKAVMPEAIGVFI 123
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS++ L L G++ + + + EM ++ +D IVN D D A ++
Sbjct 124 LPPSRDELERRLTGRGQDSQEVIASRMAQAVSEM--SHYKEYDFIIVNDDFDTALADMRA 181
Query 658 LINKLD 663
+I
Sbjct 182 IIRSQR 187
>sp|Q12IL8|KGUA_SHEDO Guanylate kinase OS=Shewanella denitrificans
(strain OS217 / ATCC BAA-1090 / DSM 15013) OX=318161 GN=gmk
PE=3 SV=1
Length=207
Score = 272 bits (695), Expect = 3e-86, Method: Composition-based stats.
Identities = 52/188 (28%), Positives = 86/188 (46%), Gaps = 2/188 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ P G++ L L+ + +V HTTR+ R EV G+ YHFVS +
Sbjct 2 SARGNLFIVSAPSGAGKSSLITALLKDKPQDMQVSVSHTTRAPRPGEVDGQHYHFVSVEQ 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F+A IA F E E N YGTS + ++ G L + Q + ++ + +
Sbjct 62 FKALIAENAFFESAEVFGNFYGTSRQVIENTLSLGIDVFLDIDWQGAQQVKKIMPEAIGV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS+ L L G++ + + EM ++ + +D I+N D ++A +L
Sbjct 122 FILPPSKAELERRLTGRGQDSSDVIAARMAQAVSEM--SHYNEYDFVIINDDFEQALADL 179
Query 656 LRLINKLD 663
+I
Sbjct 180 KSIIFSQR 187
>sp|Q9KNM4|KGUA_VIBCH Guanylate kinase OS=Vibrio cholerae serotype
O1 (strain ATCC 39315 / El Tor Inaba N16961) OX=243277
GN=gmk PE=1 SV=2
Length=207
Score = 266 bits (679), Expect = 8e-84, Method: Composition-based stats.
Identities = 54/194 (28%), Positives = 87/194 (45%), Gaps = 5/194 (3%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDR-FASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ I+ P G++ L L+ + +V HTTR R E G YHFV ++
Sbjct 2 GKGTLYIVSAPSGAGKSSLIAALLEQNPTYAMKVSVSHTTRGMRPGEQDGVHYHFVEKEH 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F I G+F+E+ E N YGTS + +N G L + Q + +R+ + I
Sbjct 62 FIELIGKGEFLEYAEVFGNYYGTSRVWIENTLNKGIDVFLDIDWQGARQIRSQMPEAKSI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS+E L L G++ + + E + E ++ +D I+N D D A +
Sbjct 122 FILPPSKEELERRLNTRGQDSDAVIAKRMGEA--KSEISHYSEYDYVIINDDFDVALMDF 179
Query 656 LRLI--NKLDTEPQ 667
+I +L + Q
Sbjct 180 KAIIRAERLKQDKQ 193
>sp|Q87TA9|KGUA_VIBPA Guanylate kinase OS=Vibrio parahaemolyticus
serotype O3:K6 (strain RIMD 2210633) OX=223926 GN=gmk PE=3
SV=1
Length=207
Score = 264 bits (675), Expect = 3e-83, Method: Composition-based stats.
Identities = 55/194 (28%), Positives = 87/194 (45%), Gaps = 5/194 (3%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDR-FASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ I+ P G++ L ++ + +V HTTR+ R E G YHFV+++
Sbjct 2 GKGTLYIVSAPSGAGKSSLISAMLERNPTYAMKVSVSHTTRNMRPGEEDGVHYHFVAKEE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE IA G F+E+ E N YGTS + + + G L + Q + +R K I
Sbjct 62 FETLIAKGDFLEYAEVFGNYYGTSRVWIEETLEKGIDVFLDIDWQGARQIREQMPKAKSI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS L L G++ + + E + E ++ +D IVN D D A +
Sbjct 122 FILPPSNGELERRLNTRGQDSAEVIAKRMAEA--KSEISHYSEYDYVIVNDDFDTALMDF 179
Query 656 LRLI--NKLDTEPQ 667
++ +L E Q
Sbjct 180 KAILRAERLKEEKQ 193
>sp|Q7MPW9|KGUA_VIBVY Guanylate kinase OS=Vibrio vulnificus (strain
YJ016) OX=196600 GN=gmk PE=3 SV=1
Length=207
Score = 263 bits (671), Expect = 1e-82, Method: Composition-based stats.
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 5/194 (3%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDR-FASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ I+ P G++ L ++ K +V HTTR R E G YHFV ++
Sbjct 2 GKGTLYIVSAPSGAGKSSLISAMLEKNPTYAMKVSVSHTTRGMRPGEQDGVHYHFVEKEH 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+F+E+ E N YGTS + ++ G L + Q + +R I
Sbjct 62 FEDLITKGEFLEYAEVFGNYYGTSRVWIENTLDKGIDVFLDIDWQGARQIREQMPHAKSI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS L L G++ + + + E + E ++ + +D I+N D D A +
Sbjct 122 FILPPSNGELERRLNTRGQDSEAVIAKRMAEA--KSEISHYNEYDYVIINDDFDTALMDF 179
Query 656 LRLI--NKLDTEPQ 667
+I +L + Q
Sbjct 180 KAIIRAERLKQDKQ 193
>sp|Q8DDV6|KGUA_VIBVU Guanylate kinase OS=Vibrio vulnificus (strain
CMCP6) OX=216895 GN=gmk PE=3 SV=1
Length=207
Score = 263 bits (671), Expect = 1e-82, Method: Composition-based stats.
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 5/194 (3%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDR-FASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ I+ P G++ L ++ K +V HTTR R E G YHFV ++
Sbjct 2 GKGTLYIVSAPSGAGKSSLISAMLEKNPTYAMKVSVSHTTRGMRPGEQDGVHYHFVEKEH 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+F+E+ E N YGTS + ++ G L + Q + +R I
Sbjct 62 FEDLITKGEFLEYAEVFGNYYGTSRVWIENTLDKGIDVFLDIDWQGARQIREQMPHAKSI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS L L G++ + + + E + E ++ + +D I+N D D A +
Sbjct 122 FILPPSNGELERRLNTRGQDSEAVIAKRMAEA--KSEISHYNEYDYVIINDDFDTALMDF 179
Query 656 LRLI--NKLDTEPQ 667
+I +L + Q
Sbjct 180 KAIIRAERLKQDKQ 193
>sp|Q9X6M5|KGUA_SALTY Guanylate kinase OS=Salmonella typhimurium
(strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=gmk PE=3
SV=1
Length=207
Score = 262 bits (670), Expect = 2e-82, Method: Composition-based stats.
Identities = 55/187 (29%), Positives = 87/187 (47%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + +V HTTR+ R EV G Y FV+ F
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRAPRPGEVHGEHYFFVNHDEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I F+EH E N YGTS +++ QV+ +G L + Q + +R + IF
Sbjct 63 KTMIGREAFLEHAEVFGNYYGTSRETIEQVLATGVDVFLDIDWQGAQQIREKMPQARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+ L L G++ + + + + EM ++ +D IVN D D A +L
Sbjct 123 ILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEM--SHYAEYDYLIVNDDFDTALSDLK 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRAER 187
>sp|O97758|ZO1_CANLF Tight junction protein ZO-1 OS=Canis lupus
familiaris OX=9615 GN=TJP1 PE=1 SV=1
Length=1769
Score = 288 bits (737), Expect = 2e-82, Method: Composition-based stats.
Identities = 88/477 (18%), Positives = 185/477 (39%), Gaps = 74/477 (16%)
Query 213 NTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGG---ETVKIVRIEKARDIPLGA 269
P + + +V + ++ L + V + G ++K+V+ K + L
Sbjct 377 QAPSLPEPKPVYAQVGQPDVDLPVSPSDGVLPNSTHEDGILRPSMKLVKFRKGDSVGLRL 436
Query 270 TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLT 329
N++ + ++ +++ A K G L EGD++L +N ++ E L D+
Sbjct 437 AGGNDV-GIFVAGVLEDSPAAKEG-LEEGDQILRVNNVDFTNIIREEAVLFLLDLPKGEE 494
Query 330 FVLIPSQQIKPPPA-----KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVIS- 383
++ ++ +++ HF+Y+ GLSF KG++ V+
Sbjct 495 VTILAQKKKDVYRRIVESDVGDSFYIRTHFEYEKESP-------YGLSFNKGEVFRVVDT 547
Query 384 --QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKS-----GKLW 436
W A R G + G++P K+ +Q +++ T+ + +++ L
Sbjct 548 LYNGKLGSWLAIRIGKNHKEVERGIIPNKNRAEQLASVQYTLPKTAGGDRADFWRFRGLR 607
Query 437 CAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELR 496
+K+N +K ++ L + E + E RP+ + GP + R
Sbjct 608 SSKRNLRKSREDLSAQPVQTKFPAYERVVLREAGFL-------RPVTIFGPI---ADVAR 657
Query 497 QRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLY 556
++L +E D + A + DQ +G
Sbjct 658 EKLAREEPDIYQIAKSEPRDAGTDQRSSGI------------------------------ 687
Query 557 GTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRA---LLAKEG 613
+ +++Q+I+ K LL + ++ L + P ++F+ P S++ ++ L E
Sbjct 688 -IRLHTIKQIIDQDKHALLDVTPNAVDRLNYAQWYPIVVFLNPDSKQGVKTMRMRLCPES 746
Query 614 KNPKPEELREIIEKTREMEQNNGHYFDTAI-VNSDLDKAYQELLRLINKLDTEPQWV 669
+ + R++ E++ ++ +NN H F T I +NS D Y L I + + WV
Sbjct 747 R----KSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWYGALKEAIQQQQNQLVWV 799
Score = 59.7 bits (143), Expect = 8e-08, Method: Composition-based stats.
Identities = 28/115 (24%), Positives = 46/115 (40%), Gaps = 5/115 (4%)
Query 223 AHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISR 282
A D+ A +E L P +D R S V +V+ K + L + +
Sbjct 155 ARDRSASRERSLSPRSDRRSVASSQPPKPTKVTLVKSRKNEEYGLRLA-----SHIFVKE 209
Query 283 IVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
I + A + G + EGD VL+ING + + L+ G L V+ ++
Sbjct 210 ISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQRDER 264
Score = 52.8 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 21/97 (22%), Positives = 39/97 (40%), Gaps = 11/97 (11%)
Query 257 VRIEKARDIPLGATVRNEMD---------SVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
V + +A G + D S++IS ++KGG AE G L E D V +NG+
Sbjct 24 VTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVLKGGPAE--GQLQENDRVAMVNGV 81
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAK 344
+ + L + ++++ P ++
Sbjct 82 SMDNVEHAFAVQQLRKSGKNAKITIRRKKKVQIPVSR 118
>sp|Q088T7|KGUA_SHEFN Guanylate kinase OS=Shewanella frigidimarina
(strain NCIMB 400) OX=318167 GN=gmk PE=3 SV=1
Length=207
Score = 262 bits (669), Expect = 2e-82, Method: Composition-based stats.
Identities = 54/188 (29%), Positives = 83/188 (44%), Gaps = 2/188 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ P G++ L L+ + +V HTTR R EV G+ YHF++ +
Sbjct 2 STRGNLFIVSAPSGAGKSSLISTLLKDKPSDKQVSVSHTTRKPRPGEVDGQHYHFITVEQ 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F+A IA FIE E N YGTS + Q ++ G L + Q + ++ +
Sbjct 62 FKALIAQNAFIEWAEVFGNFYGTSKLVIEQTLDKGIDVFLDIDWQGAEQVKKLMETAIGV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS+ L L G++ + + + EM + F IVN D D A +L
Sbjct 122 FILPPSKAELERRLTGRGQDSQQVIDSRMAQAVSEMSHYAQYEF--IIVNDDFDNALADL 179
Query 656 LRLINKLD 663
+I
Sbjct 180 SAIIRSQR 187
>sp|Q07157|ZO1_HUMAN Tight junction protein ZO-1 OS=Homo sapiens
OX=9606 GN=TJP1 PE=1 SV=3
Length=1748
Score = 288 bits (736), Expect = 4e-82, Method: Composition-based stats.
Identities = 89/477 (19%), Positives = 186/477 (39%), Gaps = 74/477 (16%)
Query 213 NTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGG---ETVKIVRIEKARDIPLGA 269
TP + + +V + ++ L + V + G ++K+V+ K + L
Sbjct 378 QTPSLPEPKPVYAQVGQPDVDLPVSPSDGVLPNSTHEDGILRPSMKLVKFRKGDSVGLRL 437
Query 270 TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLT 329
N++ + ++ +++ A K G L EGD++L +N ++ E L D+
Sbjct 438 AGGNDV-GIFVAGVLEDSPAAKEG-LEEGDQILRVNNVDFTNIIREEAVLFLLDLPKGEE 495
Query 330 FVLIPSQQIKPPPA-----KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVIS- 383
++ ++ +++ HF+Y+ GLSF KG++ V+
Sbjct 496 VTILAQKKKDVYRRIVESDVGDSFYIRTHFEYEKESP-------YGLSFNKGEVFRVVDT 548
Query 384 --QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKS-----GKLW 436
W A R G + G++P K+ +Q +++ T+ + +++ L
Sbjct 549 LYNGKLGSWLAIRIGKNHKEVERGIIPNKNRAEQLASVQYTLPKTAGGDRADFWRFRGLR 608
Query 437 CAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELR 496
+K+N +K ++ L + E + E RP+ + GP + R
Sbjct 609 SSKRNLRKSREDLSAQPVQTKFPAYERVVLREAGFL-------RPVTIFGPI---ADVAR 658
Query 497 QRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLY 556
++L +E D + A + DQ +G
Sbjct 659 EKLAREEPDIYQIAKSEPRDAGTDQRSSGI------------------------------ 688
Query 557 GTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRA---LLAKEG 613
+ +++Q+I+ K LL + ++ L + P ++F+ P S++ ++ L E
Sbjct 689 -IRLHTIKQIIDQDKHALLDVTPNAVDRLNYAQWYPIVVFLNPDSKQGVKTMRMRLCPES 747
Query 614 KNPKPEELREIIEKTREMEQNNGHYFDTAI-VNSDLDKAYQELLRLINKLDTEPQWV 669
+ + R++ E++ ++ +NN H F T I +NS D Y L I + + WV
Sbjct 748 R----KSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWYGALKEAIQQQQNQLVWV 800
Score = 59.3 bits (142), Expect = 1e-07, Method: Composition-based stats.
Identities = 27/113 (24%), Positives = 45/113 (40%), Gaps = 5/113 (4%)
Query 225 DKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIV 284
D+ A +E L P +D R S V +V+ K + L + + I
Sbjct 158 DRSASRERSLSPRSDRRSVASSQPAKPTKVTLVKSRKNEEYGLRLA-----SHIFVKEIS 212
Query 285 KGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
+ A + G + EGD VL+ING + + L+ G L V+ ++
Sbjct 213 QDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQRDER 265
Score = 52.4 bits (124), Expect = 1e-05, Method: Composition-based stats.
Identities = 21/97 (22%), Positives = 39/97 (40%), Gaps = 11/97 (11%)
Query 257 VRIEKARDIPLGATVRNEMD---------SVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
V + +A G + D S++IS ++KGG AE G L E D V +NG+
Sbjct 24 VTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVLKGGPAE--GQLQENDRVAMVNGV 81
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAK 344
+ + L + ++++ P ++
Sbjct 82 SMDNVEHAFAVQQLRKSGKNAKITIRRKKKVQIPVSR 118
>sp|Q8Z2H9|KGUA_SALTI Guanylate kinase OS=Salmonella typhi OX=90370
GN=gmk PE=3 SV=1
Length=207
Score = 261 bits (667), Expect = 4e-82, Method: Composition-based stats.
Identities = 55/187 (29%), Positives = 87/187 (47%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + +V HTTR+ R EV G Y FV+ F
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRAPRPGEVHGEHYFFVNHDEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I F+EH E N YGTS +++ QV+ +G L + Q + +R + IF
Sbjct 63 KTMIGREAFLEHAEVFGNYYGTSRETIEQVLATGVDVFLDIDWQGAQQIREKMPQARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+ L L G++ + + + + EM ++ +D IVN D D A +L
Sbjct 123 ILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEM--SHYAEYDYLIVNDDFDTALSDLK 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRAER 187
>sp|Q5PC40|KGUA_SALPA Guanylate kinase OS=Salmonella paratyphi
A (strain ATCC 9150 / SARB42) OX=295319 GN=gmk PE=3 SV=1
Length=207
Score = 261 bits (667), Expect = 4e-82, Method: Composition-based stats.
Identities = 55/187 (29%), Positives = 87/187 (47%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + +V HTTR+ R EV G Y FV+ F
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRAPRPGEVHGEHYFFVNHDEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I F+EH E N YGTS +++ QV+ +G L + Q + +R + IF
Sbjct 63 KTMIGREAFLEHAEVFGNYYGTSRETIEQVLATGVDVFLDIDWQGAQQIREKMPQARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+ L L G++ + + + + EM ++ +D IVN D D A +L
Sbjct 123 ILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEM--SHYAEYDYLIVNDDFDTALSDLK 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRAER 187
>sp|Q31UQ6|KGUA_SHIBS Guanylate kinase OS=Shigella boydii serotype
4 (strain Sb227) OX=300268 GN=gmk PE=3 SV=1
Length=207
Score = 261 bits (666), Expect = 7e-82, Method: Composition-based stats.
Identities = 55/187 (29%), Positives = 86/187 (46%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + +V HTTR R EV G Y FV+ F
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQPRPGEVHGEHYFFVNHDEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I+ F+EH E N YGTS +++ QV+ +G L + Q + +R IF
Sbjct 63 KEMISRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+ L L G++ + + + + EM ++ +D IVN D D A +L
Sbjct 123 ILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEM--SHYDEYDYLIVNDDFDTALTDLK 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRAER 187
>sp|Q3YW11|KGUA_SHISS Guanylate kinase OS=Shigella sonnei (strain
Ss046) OX=300269 GN=gmk PE=3 SV=1
Length=207
Score = 260 bits (664), Expect = 1e-81, Method: Composition-based stats.
Identities = 55/187 (29%), Positives = 86/187 (46%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + +V HTTR R EV G Y FV+ F
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQPRPGEVHGEHYFFVNHDEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I+ F+EH E N YGTS +++ QV+ +G L + Q + +R IF
Sbjct 63 KEMISRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+ L L G++ + + + + EM ++ +D IVN D D A +L
Sbjct 123 ILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEM--SHYAEYDYLIVNDDFDTALTDLK 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRAER 187
>sp|P60548|KGUA_SHIFL Guanylate kinase OS=Shigella flexneri OX=623
GN=gmk PE=3 SV=1
Length=207
Score = 260 bits (664), Expect = 1e-81, Method: Composition-based stats.
Identities = 55/187 (29%), Positives = 86/187 (46%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + +V HTTR R EV G Y FV+ F
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQPRPGEVHGEHYFFVNHDEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I+ F+EH E N YGTS +++ QV+ +G L + Q + +R IF
Sbjct 63 KEMISRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+ L L G++ + + + + EM ++ +D IVN D D A +L
Sbjct 123 ILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEM--SHYAEYDYLIVNDDFDTALTDLK 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRAER 187
>sp|Q1R4U3|KGUA_ECOUT Guanylate kinase OS=Escherichia coli (strain
UTI89 / UPEC) OX=364106 GN=gmk PE=3 SV=2
Length=207
Score = 260 bits (664), Expect = 1e-81, Method: Composition-based stats.
Identities = 55/187 (29%), Positives = 86/187 (46%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + +V HTTR R EV G Y FV+ F
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQPRPGEVHGEHYFFVNHDEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I+ F+EH E N YGTS +++ QV+ +G L + Q + +R IF
Sbjct 63 KEMISRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+ L L G++ + + + + EM ++ +D IVN D D A +L
Sbjct 123 ILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEM--SHYAEYDYLIVNDDFDTALTDLK 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRAER 187
>sp|P60546|KGUA_ECOLI Guanylate kinase OS=Escherichia coli (strain
K12) OX=83333 GN=gmk PE=1 SV=1
Length=207
Score = 260 bits (664), Expect = 1e-81, Method: Composition-based stats.
Identities = 55/187 (29%), Positives = 86/187 (46%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + +V HTTR R EV G Y FV+ F
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQPRPGEVHGEHYFFVNHDEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I+ F+EH E N YGTS +++ QV+ +G L + Q + +R IF
Sbjct 63 KEMISRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+ L L G++ + + + + EM ++ +D IVN D D A +L
Sbjct 123 ILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEM--SHYAEYDYLIVNDDFDTALTDLK 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRAER 187
>sp|P60547|KGUA_ECOL6 Guanylate kinase OS=Escherichia coli O6:H1
(strain CFT073 / ATCC 700928 / UPEC) OX=199310 GN=gmk PE=3
SV=1
Length=207
Score = 260 bits (664), Expect = 1e-81, Method: Composition-based stats.
Identities = 55/187 (29%), Positives = 86/187 (46%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + +V HTTR R EV G Y FV+ F
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQPRPGEVHGEHYFFVNHDEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I+ F+EH E N YGTS +++ QV+ +G L + Q + +R IF
Sbjct 63 KEMISRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+ L L G++ + + + + EM ++ +D IVN D D A +L
Sbjct 123 ILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEM--SHYAEYDYLIVNDDFDTALTDLK 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRAER 187
>sp|Q0TBG1|KGUA_ECOL5 Guanylate kinase OS=Escherichia coli O6:K15:H31
(strain 536 / UPEC) OX=362663 GN=gmk PE=3 SV=1
Length=207
Score = 260 bits (664), Expect = 1e-81, Method: Composition-based stats.
Identities = 55/187 (29%), Positives = 86/187 (46%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + +V HTTR R EV G Y FV+ F
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQPRPGEVHGEHYFFVNHDEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I+ F+EH E N YGTS +++ QV+ +G L + Q + +R IF
Sbjct 63 KEMISRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+ L L G++ + + + + EM ++ +D IVN D D A +L
Sbjct 123 ILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEM--SHYAEYDYLIVNDDFDTALTDLK 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRAER 187
>sp|P39447|ZO1_MOUSE Tight junction protein ZO-1 OS=Mus musculus
OX=10090 GN=Tjp1 PE=1 SV=2
Length=1745
Score = 286 bits (732), Expect = 1e-81, Method: Composition-based stats.
Identities = 87/477 (18%), Positives = 184/477 (39%), Gaps = 74/477 (16%)
Query 213 NTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGG---ETVKIVRIEKARDIPLGA 269
TP + + +V + ++ L + + G ++K+V+ K + L
Sbjct 378 QTPTLPEPKPVYAQVGQPDVDLPVSPSDGALPNSAHEDGILRPSMKLVKFRKGDSVGLRL 437
Query 270 TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLT 329
N++ + ++ +++ A K G L EGD++L +N ++ E L D+
Sbjct 438 AGGNDV-GIFVAGVLEDSPAAKEG-LEEGDQILRVNNVDFTNIIREEAVLFLLDLPKGEE 495
Query 330 FVLIPSQQIKPPPA-----KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVIS- 383
++ ++ +++ HF+Y+ GLSF KG++ V+
Sbjct 496 VTILAQKKKDVYRRIVESDVGDSFYIRTHFEYEKESP-------YGLSFNKGEVFRVVDT 548
Query 384 --QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKS-----GKLW 436
W A R G + G++P K+ +Q +++ T+ + +++ L
Sbjct 549 LYNGKLGSWLAIRIGKNHKEVERGIIPNKNRAEQLASVQYTLPKTAGGDRADFWRFRGLR 608
Query 437 CAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELR 496
+K+N +K ++ L + E + E RP+ + GP + R
Sbjct 609 SSKRNLRKSREDLSAQPVQTKFPAYERVVLREAGFL-------RPVTIFGPI---ADVAR 658
Query 497 QRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLY 556
++L +E D + A + D +G
Sbjct 659 EKLAREEPDIYQIAKSEPRDAGTDHRSSGI------------------------------ 688
Query 557 GTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRA---LLAKEG 613
+ +++Q+I+ K LL + ++ L + P ++F+ P S++ ++ L E
Sbjct 689 -IRLHTIKQIIDQDKHALLDVTPNAVDRLNYAQWYPIVVFLNPDSKQGVKTMRMRLCPES 747
Query 614 KNPKPEELREIIEKTREMEQNNGHYFDTAI-VNSDLDKAYQELLRLINKLDTEPQWV 669
+ + R++ E++ ++ +NN H F T I +NS D Y L I + + WV
Sbjct 748 R----KSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWYGALKEAIQQQQNQLVWV 800
Score = 59.7 bits (143), Expect = 8e-08, Method: Composition-based stats.
Identities = 28/115 (24%), Positives = 46/115 (40%), Gaps = 5/115 (4%)
Query 223 AHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISR 282
A D+ A +E L P +D R S V +V+ K + L + +
Sbjct 156 ARDRSASRERSLSPRSDRRSVASSQPAKPTKVTLVKSRKNEEYGLRLA-----SHIFVKE 210
Query 283 IVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
I + A + G + EGD VL+ING + + L+ G L V+ ++
Sbjct 211 ISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQRDER 265
Score = 51.6 bits (122), Expect = 2e-05, Method: Composition-based stats.
Identities = 21/97 (22%), Positives = 38/97 (39%), Gaps = 11/97 (11%)
Query 257 VRIEKARDIPLGATVRNEMD---------SVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
V + +A G + D S++IS ++KGG AE G L E D V +NG+
Sbjct 24 VTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVLKGGPAE--GQLQENDRVAMVNGV 81
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAK 344
+ + L + ++++ P +
Sbjct 82 SMDNVEHAFAVQQLRKSGKNAKITIRRKKKVQIPVSH 118
>sp|A0A0G2K2P5|ZO1_RAT Tight junction protein ZO-1 OS=Rattus norvegicus
OX=10116 GN=Tjp1 PE=1 SV=1
Length=1765
Score = 286 bits (731), Expect = 1e-81, Method: Composition-based stats.
Identities = 89/477 (19%), Positives = 185/477 (39%), Gaps = 74/477 (16%)
Query 213 NTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGG---ETVKIVRIEKARDIPLGA 269
TP + + +V + ++ L + V + G ++K+V+ K + L
Sbjct 378 QTPTLPEPKPVYAQVGQPDVDLPVSPSDGVLPNSTHEDGILRPSMKLVKFRKGDSVGLRL 437
Query 270 TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLT 329
N++ + ++ +++ A K G L EGD++L +N ++ E L D+
Sbjct 438 AGGNDV-GIFVAGVLEDSPAAKEG-LEEGDQILRVNNVDFTNIIREEAVLFLLDLPKGEE 495
Query 330 FVLIPSQQIKPPPA-----KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVIS- 383
++ ++ +++ HF+Y+ GLSF KG++ V+
Sbjct 496 VTILAQKKKDVYRRIVESDVGDSFYIRTHFEYEKESP-------YGLSFNKGEVFRVVDT 548
Query 384 --QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKS-----GKLW 436
W A R G + G+VP K+ +Q +++ T+ + +++ L
Sbjct 549 LYNGKLGSWLAIRIGKNHKEVERGIVPNKNRAEQLASVQYTLPKTAGGDRADFWRFRGLR 608
Query 437 CAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELR 496
+K+N +K ++ L + E + E RP+ + GP + R
Sbjct 609 SSKRNLRKSREDLSAQPVQTKFPAYERVVLREAGFL-------RPVTIFGPI---ADVAR 658
Query 497 QRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLY 556
++L +E D + A + D +G
Sbjct 659 EKLAREEPDIYQIAKSEPRDAGTDHRSSGI------------------------------ 688
Query 557 GTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRA---LLAKEG 613
+ +++Q+I+ K LL + ++ L + P ++F+ P S++ ++ L E
Sbjct 689 -IRLHTIKQIIDQDKHALLDVTPNAVDRLNYAQWYPIVVFLNPDSKQGVKTMRMRLCPES 747
Query 614 KNPKPEELREIIEKTREMEQNNGHYFDTAI-VNSDLDKAYQELLRLINKLDTEPQWV 669
+ + R++ E++ ++ +NN H F T I +NS D Y L I + + WV
Sbjct 748 R----KSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWYGALKEAIQQQQNQLVWV 800
Score = 60.1 bits (144), Expect = 7e-08, Method: Composition-based stats.
Identities = 27/115 (23%), Positives = 46/115 (40%), Gaps = 5/115 (4%)
Query 223 AHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISR 282
A D+ A ++ L P +D R S V +V+ K + L + +
Sbjct 156 ARDRSASRDRSLSPRSDRRSVASSQPAKPTKVTLVKSRKNEEYGLRLA-----SHIFVKE 210
Query 283 IVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
I + A + G + EGD VL+ING + + L+ G L V+ ++
Sbjct 211 ISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQRDER 265
Score = 52.4 bits (124), Expect = 2e-05, Method: Composition-based stats.
Identities = 28/131 (21%), Positives = 52/131 (40%), Gaps = 12/131 (9%)
Query 257 VRIEKARDIPLGATVRNEMD---------SVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
V + +A G + D S++IS ++KGG AE G L E D V +NG+
Sbjct 24 VTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVLKGGPAE--GQLQENDRVAMVNGV 81
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCR 367
+ + L + ++++ P + V + D +D + P
Sbjct 82 SMDNVEHAFAVQQLRKSGKNAKITIRRKKKVQIPVSHPDPDPVSDNEDDSYDEDVHDPRS 141
Query 368 ELG-LSFQKGD 377
G L+ ++G+
Sbjct 142 GRGALANRRGE 152
>sp|Q57I92|KGUA_SALCH Guanylate kinase OS=Salmonella choleraesuis
(strain SC-B67) OX=321314 GN=gmk PE=3 SV=2
Length=207
Score = 259 bits (661), Expect = 3e-81, Method: Composition-based stats.
Identities = 55/187 (29%), Positives = 86/187 (46%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + +V HTTR+ R EV G Y FV+ F
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRAPRPGEVHGEHYFFVNHDEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I F+EH E N YGTS ++ QV+ +G L + Q + +R + IF
Sbjct 63 KTMIGREAFLEHAEVFGNYYGTSRETTEQVLATGVDVFLDIDWQGAQQIREKMPQARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+ L L G++ + + + + EM ++ +D IVN D D A +L
Sbjct 123 ILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEM--SHYAEYDYLIVNDDFDTALSDLK 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRAER 187
>sp|Q329K8|KGUA_SHIDS Guanylate kinase OS=Shigella dysenteriae
serotype 1 (strain Sd197) OX=300267 GN=gmk PE=3 SV=1
Length=207
Score = 258 bits (659), Expect = 7e-81, Method: Composition-based stats.
Identities = 55/187 (29%), Positives = 86/187 (46%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + +V HTTR R EV G Y FV+ F
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQPRPGEVHGEHYFFVNHDEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I+ F+EH E N YGTS +++ QV+ +G L + Q + +R IF
Sbjct 63 KEMISRDAFLEHAEVFDNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+ L L G++ + + + + EM ++ +D IVN D D A +L
Sbjct 123 ILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEM--SHYAEYDYLIVNDDFDTALTDLK 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRAER 187
>sp|Q8XD88|KGUA_ECO57 Guanylate kinase OS=Escherichia coli O157:H7
OX=83334 GN=gmk PE=3 SV=1
Length=207
Score = 256 bits (655), Expect = 2e-80, Method: Composition-based stats.
Identities = 54/187 (29%), Positives = 85/187 (45%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + +V HTTR R EV G Y FV+ F
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQPRPGEVHGEHYFFVNHDEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I+ F+EH E N YGTS +++ QV+ +G L + Q + +R IF
Sbjct 63 KEMISRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+ L L ++ + + + + EM ++ +D IVN D D A +L
Sbjct 123 ILPPSKIELDRRLRGRDQDSEEVIAKRMAQAVAEM--SHYAEYDYLIVNDDFDTALTDLK 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRAER 187
>sp|Q3IJH8|KGUA_PSET1 Guanylate kinase OS=Pseudoalteromonas translucida
(strain TAC 125) OX=326442 GN=gmk PE=3 SV=1
Length=206
Score = 256 bits (654), Expect = 3e-80, Method: Composition-based stats.
Identities = 53/190 (28%), Positives = 83/190 (44%), Gaps = 3/190 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
R IL P G++ L L+ K D +V HTTR++R E G YHFVS
Sbjct 1 MAQTRGNLFILSAPSGAGKSSLINALLKKHTD-MKVSVSHTTRAKRPGEENGVHYHFVST 59
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
F+A I F E + N YGTS ++ +++G L + Q + +R
Sbjct 60 DEFKALITKDDFFEWAQVFDNYYGTSKQAIESQLDAGIDVFLDIDWQGAQQVRKIMPSVQ 119
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI PPS+ L L G++ + + + E ++ + +D IVN D D A
Sbjct 120 TIFILPPSKAELEQRLNNRGQDSQEIIAGRMAQAQS--ETSHYNEYDFVIVNDDFDTALT 177
Query 654 ELLRLINKLD 663
++ ++
Sbjct 178 DIETIVMAQR 187
>sp|Q5E8P5|KGUA_ALIF1 Guanylate kinase OS=Aliivibrio fischeri
(strain ATCC 700601 / ES114) OX=312309 GN=gmk PE=3 SV=1
Length=207
Score = 256 bits (654), Expect = 4e-80, Method: Composition-based stats.
Identities = 51/194 (26%), Positives = 85/194 (44%), Gaps = 5/194 (3%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDR-FASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
++ I+ P G++ L L+ +V HTTR R E G YHF+ ++
Sbjct 2 SKGTLYIVSAPSGAGKSSLISALLESNPTYAMKVSVSHTTRGMRPGETDGVHYHFIQKEH 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+F+E+ E N YGTS + + ++ G L + Q + +R +
Sbjct 62 FEELIQKGEFLEYAEVFGNYYGTSRVWIEETLDKGIDVFLDIDWQGARQIREQMPLAKSV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS L L G++ + + E + E ++ +D I+N D D A +
Sbjct 122 FILPPSNGELERRLNARGQDSDAVIAKRMSEA--KSEISHYDEYDYVIINDDFDTAQMDF 179
Query 656 LRLI--NKLDTEPQ 667
+I +L + Q
Sbjct 180 RSIIRAERLKQDKQ 193
>sp|Q602T6|KGUA_METCA Guanylate kinase OS=Methylococcus capsulatus
(strain ATCC 33009 / NCIMB 11132 / Bath) OX=243233 GN=gmk
PE=3 SV=1
Length=204
Score = 256 bits (653), Expect = 4e-80, Method: Composition-based stats.
Identities = 53/190 (28%), Positives = 87/190 (46%), Gaps = 3/190 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ ++ P G+ L L D A +V HTTR +R EV G+DY FV + FE
Sbjct 3 QGLLYVISAPSGAGKTSLVSALCAGAPD-LAVSVSHTTRPQRPGEVPGQDYWFVDKAEFE 61
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
IA F+E+ N YGT+ +V +V+ +G+ +L + Q + +R +FI
Sbjct 62 KMIANEAFLEYARVFDNYYGTAKTTVEEVLATGRDAVLEIDWQGARQVRRLMPACVSVFI 121
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS++ L L ++ + R + EM ++ +D IVN D + A +L
Sbjct 122 LPPSRQALEQRLRTRQQDSEAVIARRMEAAISEM--SHYAEYDYLIVNDDFNLALNQLRA 179
Query 658 LINKLDTEPQ 667
++ Q
Sbjct 180 IVQTQRLTVQ 189
>sp|Q6LVP5|KGUA_PHOPR Guanylate kinase OS=Photobacterium profundum
(strain SS9) OX=298386 GN=gmk PE=3 SV=1
Length=208
Score = 255 bits (652), Expect = 6e-80, Method: Composition-based stats.
Identities = 53/194 (27%), Positives = 84/194 (43%), Gaps = 5/194 (3%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
++ I+ P G++ L L+ +V HTTR R E G Y+F+S +
Sbjct 2 SKGTLYIVSAPSGAGKSSLINALLETNPTYDMKVSVSHTTRGMRPGEENGVHYNFISVEE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F F+EH E N YGTS + +N G L + Q + +R +
Sbjct 62 FTELTEQESFLEHAEVFGNYYGTSRPWIEDQLNKGIDVFLDIDWQGARQIRIQMPAAKSL 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS+E L L G++ + R + E E+ ++ + +D IVN D D A +
Sbjct 122 FILPPSKEELERRLNARGQDSETIIARRMQEARSEI--SHYNEYDYVIVNDDFDAALMDF 179
Query 656 LRLI--NKLDTEPQ 667
+I +L + Q
Sbjct 180 KAIIRAERLKQDKQ 193
>sp|Q5QYH9|KGUA_IDILO Guanylate kinase OS=Idiomarina loihiensis
(strain ATCC BAA-735 / DSM 15497 / L2-TR) OX=283942 GN=gmk
PE=3 SV=1
Length=210
Score = 255 bits (652), Expect = 8e-80, Method: Composition-based stats.
Identities = 56/197 (28%), Positives = 88/197 (45%), Gaps = 5/197 (3%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDR-FASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
I+ P G++ L + L+ K D+ +V TTR+ R EV G YHF+S + FE
Sbjct 8 GNLFIIAAPSGAGKSSLIRALLEKHPDQSMQVSVSSTTRAPRPGEVQGVHYHFLSTEEFE 67
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I AG+F E N YGTS V ++ GK L + Q + +R + +FI
Sbjct 68 QRIDAGEFYEWARVFGNYYGTSRKVVESLLAEGKDVFLDIDWQGAQQVREHHPEVRSVFI 127
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS E L L G++ + + EM ++ H FD +VN D + + L
Sbjct 128 VPPSLEILEERLRVRGQDSDEVIAERMAKAQAEM--SHYHEFDYLLVNDDFNNSLASLEH 185
Query 658 LI--NKLDTEPQWVPST 672
++ + Q + +
Sbjct 186 IVLAQRQKMPHQQIRYS 202
>sp|Q3AC14|KGUA_CARHZ Guanylate kinase OS=Carboxydothermus hydrogenoformans
(strain ATCC BAA-161 / DSM 6008 / Z-2901) OX=246194
GN=gmk PE=3 SV=1
Length=204
Score = 255 bits (651), Expect = 8e-80, Method: Composition-based stats.
Identities = 48/193 (25%), Positives = 94/193 (49%), Gaps = 3/193 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
++ +++ GP G+ + Q + + + F ++ TTR +R E+ G Y+F+ RQ F
Sbjct 2 HKGMLVVVSGPSGAGKGTICQEIRKRNPNLF-YSISATTREKRVGEIDGVHYYFIDRQQF 60
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
E IA +F+E + N YGT V + + G+ +L + + + ++ + + +F
Sbjct 61 EKMIANDEFLEWADVYGNYYGTPKKPVFEALARGQDVILEIDIKGARQVKKTYPEGVFVF 120
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS L L K G + + ++ + E+ N ++D I+N DL+ A +L
Sbjct 121 ILPPSISILEERLRKRGTDKEEIIVKRMQMAWEEI--ANCDWYDYLILNDDLETAVNDLE 178
Query 657 RLINKLDTEPQWV 669
++ +P+ V
Sbjct 179 AVLTAEKLKPKRV 191
>sp|Q65RR5|KGUA_MANSM Guanylate kinase OS=Mannheimia succiniciproducens
(strain MBEL55E) OX=221988 GN=gmk PE=3 SV=1
Length=208
Score = 255 bits (651), Expect = 1e-79, Method: Composition-based stats.
Identities = 53/195 (27%), Positives = 90/195 (46%), Gaps = 6/195 (3%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEK-DRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
++ IL P G++ L L+ +++ + +V HTTR R E G YHFVS +
Sbjct 2 SQGNLYILSAPSGAGKSSLISALLEQDQANTMMVSVSHTTRQPRPGEENGVHYHFVSVEE 61
Query 536 FEADIAAGKFIEHGEFEK-NLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
FE I G F+E+ + N YGTS+ ++ + + G L + Q + +R
Sbjct 62 FELLINEGAFLEYAKVFGGNYYGTSLPTIEKNLAQGIDVFLDIDWQGAQQIRKKVPSVKS 121
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFI PPS L L G++ + + E+ ++ + +D I+N D +A +
Sbjct 122 IFILPPSLAELEKRLIGRGQDSAEVIADRMSKAMDEI--SHYNEYDYVIINDDFTRALAD 179
Query 655 LLRLI--NKLDTEPQ 667
L+ ++ KL Q
Sbjct 180 LVHILRAEKLTLAYQ 194
>sp|Q8TDM6|DLG5_HUMAN Disks large homolog 5 OS=Homo sapiens OX=9606
GN=DLG5 PE=1 SV=4
Length=1919
Score = 280 bits (717), Expect = 1e-79, Method: Composition-based stats.
Identities = 89/445 (20%), Positives = 187/445 (42%), Gaps = 51/445 (11%)
Query 255 KIVRIEKARDIPLGA-TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
++V I+K++ + LG + V ++ + A+ L GD +LE +++R K
Sbjct 1501 RVVFIKKSQ-LELGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKT 1559
Query 314 VNEVFDLLSDMHGTLTFVL--IPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGL 371
V EV+ + + + P + K +++A +D + E L
Sbjct 1560 VEEVYVEMLKPRDGVRLKVQYRPEEFTKAKGLPGDSFYIRALYDR-------LADVEQEL 1612
Query 372 SFQKGDILHV---ISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKE 428
SF+K DIL+V + Q W A++ + + G +P K Q + + ++ E K+
Sbjct 1613 SFKKDDILYVDDTLPQGTFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKD 1672
Query 429 PEKSGKLWCAK------KNKKKRKKVLYNANKN----DDYDNEEILTYEE-MSLYHQPAN 477
+ K A + K K K+ K+ D + ++ I +E+ +SL +Q
Sbjct 1673 DNSATKTLSAAARRSFFRRKHKHKRSGSKDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQ 1732
Query 478 RK-----RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVS 532
+ RP++++GP + +++ L+N+ +F ++ S
Sbjct 1733 KVDCTALRPVLILGPL---LDVVKEMLVNEAPGKFCRCPLEVMKA--------------S 1775
Query 533 RQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKP 592
+QA E + F+++ + T++ S++++ + CLL + +++ L + + P
Sbjct 1776 QQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNRHCLLDIAPHAIERLHHMHIYP 1835
Query 593 YIIFIAPPS---QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLD 649
+IFI S + R + K + +E E +++EQ YF I L
Sbjct 1836 IVIFIHYKSAKHIKEQRDPIYLRDKVTQ-RHSKEQFEAAQKLEQEYSRYFTGVIQGGALS 1894
Query 650 KAYQELLRLINKLDTEPQWVPSTWL 674
++L ++N+ + W+P+ L
Sbjct 1895 SICTQILAMVNQEQNKVLWIPACPL 1919
Score = 61.6 bits (148), Expect = 2e-08, Method: Composition-based stats.
Identities = 23/111 (21%), Positives = 48/111 (43%), Gaps = 3/111 (3%)
Query 226 KVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV-RNEMDSVIISRIV 284
A ++ + E + V+++K + PLG ++ E + +S++
Sbjct 1320 TSASTLPRIAVNPASLGERRKDRPYVEEPRHVKVQKGSE-PLGISIVSGEKGGIYVSKVT 1378
Query 285 KGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
G A ++G L GD++LE NGI +R + ++ T+T + +
Sbjct 1379 VGSIAHQAG-LEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYN 1428
Score = 57.0 bits (136), Expect = 5e-07, Method: Composition-based stats.
Identities = 26/97 (27%), Positives = 39/97 (40%), Gaps = 14/97 (14%)
Query 256 IVRIEKARD----IPLGATVRNEMD-------SVIISRIVKGGAAEKSGLLHEGDEVLEI 304
+VR K+ PL + + D V + ++ G A K G L GD ++ I
Sbjct 705 VVRRRKSLGGKVVTPLHINLSGQKDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAI 764
Query 305 NGIEIRGKDVNEVFDLLSDMHGTLT---FVLIPSQQI 338
NGI + K +NE LL +LT + P
Sbjct 765 NGIALDNKSLNECESLLRSCQDSLTLSLLKVFPQSSS 801
>sp|O34328|KGUA_BACSU Guanylate kinase OS=Bacillus subtilis (strain
168) OX=224308 GN=gmk PE=3 SV=2
Length=204
Score = 253 bits (647), Expect = 3e-79, Method: Composition-based stats.
Identities = 55/183 (30%), Positives = 89/183 (49%), Gaps = 2/183 (1%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R I+L GP G+ +RQ + ++E +F ++ TTRS R+ EV G DY F +R F
Sbjct 3 ERGLLIVLSGPSGVGKGTVRQAIFSQEDTKFEYSISVTTRSPREGEVNGVDYFFKTRDEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
E IA K +E E+ N YGT +D V Q + GK L + Q +RN+ + IF
Sbjct 63 EQMIADNKLLEWAEYVGNYYGTPVDYVEQTLQDGKDVFLEIEVQGALQVRNAFPEGLFIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+APPS L+ + G + E+E + +D + N +++ A ++
Sbjct 123 LAPPSLSELKNRIVTRGTETDALIENRMKAAKAEIEMMDA--YDYVVENDNVETACDKIK 180
Query 657 RLI 659
++
Sbjct 181 AIV 183
>sp|P44310|KGUA_HAEIN Guanylate kinase OS=Haemophilus influenzae
(strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=gmk
PE=3 SV=1
Length=208
Score = 254 bits (648), Expect = 3e-79, Method: Composition-based stats.
Identities = 50/192 (26%), Positives = 87/192 (45%), Gaps = 4/192 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFA-SAVPHTTRSRRDQEVAGRDYHFVSRQA 535
++ IL P G++ L L+ + +V HTTR+ R EV G Y+FVS++
Sbjct 2 SQGNLYILSAPSGAGKSSLISALLASDSSTQKMVSVSHTTRAPRPGEVEGVHYYFVSKEE 61
Query 536 FEADIAAGKFIEHGEFEK-NLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
FE+ I F+E+ + N YGTS+ ++ + + G L + Q + +R
Sbjct 62 FESLIEQDLFLEYAKVFGGNYYGTSLPAIEENLAKGIDVFLDIDWQGAQQIRKKVPSVKS 121
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFI PPS L L G++ + + + E+ ++ +D IVN D +K ++
Sbjct 122 IFILPPSLPELERRLIGRGQDSEEVIAERMSKAMSEI--SHYDEYDYVIVNDDFEKTLKD 179
Query 655 LLRLINKLDTEP 666
L ++
Sbjct 180 LQSILQSERLTK 191
>sp|Q66GE5|KGUA_YERPS Guanylate kinase OS=Yersinia pseudotuberculosis
serotype I (strain IP32953) OX=273123 GN=gmk PE=3 SV=1
Length=207
Score = 253 bits (647), Expect = 3e-79, Method: Composition-based stats.
Identities = 52/187 (28%), Positives = 85/187 (45%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + ++ HTTR++R E G Y FVS + F
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSISHTTRAKRPGENHGEHYFFVSEKEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
I F+EH + +N YGTS ++ QV+ +G L + Q + +R IF
Sbjct 63 CQMIDDDAFLEHAKVFENYYGTSRLAIEQVLATGVDVFLDIDWQGAQQIRAKMPTARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+ L L G++ + + + + EM + +D IVN D + A +L
Sbjct 123 ILPPSKTELDRRLRGRGQDSEEVIAKRMEQAVAEM--AHYAEYDYLIVNDDFNLALSDLK 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRAER 187
>sp|Q1CCZ3|KGUA_YERPN Guanylate kinase OS=Yersinia pestis bv.
Antiqua (strain Nepal516) OX=377628 GN=gmk PE=3 SV=1
Length=207
Score = 253 bits (647), Expect = 3e-79, Method: Composition-based stats.
Identities = 52/187 (28%), Positives = 85/187 (45%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + ++ HTTR++R E G Y FVS + F
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSISHTTRAKRPGENHGEHYFFVSEKEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
I F+EH + +N YGTS ++ QV+ +G L + Q + +R IF
Sbjct 63 CQMIDDDAFLEHAKVFENYYGTSRLAIEQVLATGVDVFLDIDWQGAQQIRAKMPTARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+ L L G++ + + + + EM + +D IVN D + A +L
Sbjct 123 ILPPSKTELDRRLRGRGQDSEEVIAKRMEQAVAEM--AHYAEYDYLIVNDDFNLALSDLK 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRAER 187
>sp|Q8ZJQ2|KGUA_YERPE Guanylate kinase OS=Yersinia pestis OX=632
GN=gmk PE=3 SV=1
Length=207
Score = 253 bits (647), Expect = 3e-79, Method: Composition-based stats.
Identities = 52/187 (28%), Positives = 85/187 (45%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + ++ HTTR++R E G Y FVS + F
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSISHTTRAKRPGENHGEHYFFVSEKEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
I F+EH + +N YGTS ++ QV+ +G L + Q + +R IF
Sbjct 63 CQMIDDDAFLEHAKVFENYYGTSRLAIEQVLATGVDVFLDIDWQGAQQIRAKMPTARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+ L L G++ + + + + EM + +D IVN D + A +L
Sbjct 123 ILPPSKTELDRRLRGRGQDSEEVIAKRMEQAVAEM--AHYAEYDYLIVNDDFNLALSDLK 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRAER 187
>sp|Q1C258|KGUA_YERPA Guanylate kinase OS=Yersinia pestis bv.
Antiqua (strain Antiqua) OX=360102 GN=gmk PE=3 SV=1
Length=207
Score = 253 bits (647), Expect = 3e-79, Method: Composition-based stats.
Identities = 52/187 (28%), Positives = 85/187 (45%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + ++ HTTR++R E G Y FVS + F
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSISHTTRAKRPGENHGEHYFFVSEKEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
I F+EH + +N YGTS ++ QV+ +G L + Q + +R IF
Sbjct 63 CQMIDDDAFLEHAKVFENYYGTSRLAIEQVLATGVDVFLDIDWQGAQQIRAKMPTARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+ L L G++ + + + + EM + +D IVN D + A +L
Sbjct 123 ILPPSKTELDRRLRGRGQDSEEVIAKRMEQAVAEM--AHYAEYDYLIVNDDFNLALSDLK 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRAER 187
>sp|Q0I5L8|KGUA_HISS1 Guanylate kinase OS=Histophilus somni (strain
129Pt) OX=205914 GN=gmk PE=3 SV=2
Length=208
Score = 253 bits (647), Expect = 4e-79, Method: Composition-based stats.
Identities = 52/188 (28%), Positives = 90/188 (48%), Gaps = 4/188 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEK-DRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R I+ P G++ L L+ ++K D ++ HTTRS R E+ G YHFVS + F
Sbjct 3 RGNLYIISAPSGAGKSSLISALLERDKNDSMTVSISHTTRSPRPGEIDGVHYHFVSHEKF 62
Query 537 EADIAAGKFIEHGEFEK-NLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
E I F+E+ + N YGTS+ ++ + + +G L + Q + +R I
Sbjct 63 EQLILENSFLEYAKVFGGNYYGTSLLNIEKNLAAGIDVFLDIDWQGARQIREKRPDVKSI 122
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS L L G++ + + + + E+ ++ +D I+N+D D+A +L
Sbjct 123 FILPPSISALEKRLIGRGQDSQDIIAKRMEKAADEI--SHYDEYDYVIINADFDQALVDL 180
Query 656 LRLINKLD 663
++
Sbjct 181 EHILRAER 188
>sp|Q479A8|KGUA_DECAR Guanylate kinase OS=Dechloromonas aromatica
(strain RCB) OX=159087 GN=gmk PE=3 SV=1
Length=202
Score = 253 bits (646), Expect = 4e-79, Method: Composition-based stats.
Identities = 52/182 (29%), Positives = 81/182 (45%), Gaps = 3/182 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
++ P G+ L + L+ +E ++ +TTR R E GR+YHFV F A
Sbjct 3 GNLFVVAAPSGAGKTTLVRMLLEQESS-VNLSISYTTRHPRPGEQNGREYHFVETPEFRA 61
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
IA +F+E E N YGTS + + +G+ LL + Q + +R + +FI
Sbjct 62 MIARQEFLEWAEVHGNFYGTSKKWIADQLAAGRDVLLEIDWQGAQQVRALFPQAIGVFIL 121
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS E L L G + R + EM + FD I+N L +A +L +
Sbjct 122 PPSMEELTRRLTGRGTDSPDVIDRRLAAAQAEMR--HVGEFDYVIINDQLAQALDDLRAV 179
Query 659 IN 660
+
Sbjct 180 VR 181
>sp|Q7N9P2|KGUA_PHOLL Guanylate kinase OS=Photorhabdus laumondii
subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01) OX=243265
GN=gmk PE=3 SV=1
Length=207
Score = 253 bits (647), Expect = 4e-79, Method: Composition-based stats.
Identities = 52/187 (28%), Positives = 84/187 (45%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + +V HTTR+ R E G Y F++ +AF
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRAMRPGENQGEHYFFITEEAF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
I +F+EH N YGTS + + + SG L + Q + +R IF
Sbjct 63 RQMIDNNEFLEHARVFDNYYGTSRKVIEETLASGVDVFLDIDWQGAQQIRKKMPSARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+E L L G++ + + + + EM + + +D IVN D + A +L
Sbjct 123 ILPPSKEELCRRLRGRGQDSEDIIEKRMDQAVAEM--VHYNEYDYLIVNDDFNTALADLH 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRSER 187
>sp|O95049|ZO3_HUMAN Tight junction protein ZO-3 OS=Homo sapiens
OX=9606 GN=TJP3 PE=1 SV=3
Length=919
Score = 273 bits (697), Expect = 7e-79, Method: Composition-based stats.
Identities = 96/470 (20%), Positives = 174/470 (37%), Gaps = 86/470 (18%)
Query 229 EQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGA 288
E + + + E G ++VR K + I L N++ + +S + G
Sbjct 358 ESSYDIYRVPSSQSMEDRGYSP--DTRVVRFLKGKSIGLRLAGGNDV-GIFVSGVQAGSP 414
Query 289 AEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS--DMHGTLTFVLIPSQQIKPPPAKET 346
A+ G + EGD++L++N + + E L + V Q I +
Sbjct 415 ADGQG-IQEGDQILQVNDVPFQNLTREEAVQFLLGLPPGEEMELVTQRKQDIFWKMVQSR 473
Query 347 ---VIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPN---------WWQAYR 394
+++ HF+ +PS GL F +GD+ HV+ P W A R
Sbjct 474 VGDSFYIRTHFELEPSPPS-------GLGFTRGDVFHVLDTLHPGPGQSHARGGHWLAVR 526
Query 395 EGDEDNQPLAGLVPGKSFQQQREAMKQTIE-------EDKEPEKSGKLW-------CAKK 440
G + + G++P +S +Q +++ + W AKK
Sbjct 527 MGRDLREQERGIIPNQSRAEQLASLEAAQRAVGVGPGSSAGSNARAEFWRLRGLRRGAKK 586
Query 441 NKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLM 500
++ ++ L + Y E + E S KRP++++GP + Q+L
Sbjct 587 TTQRSREDLSALTRQGRYPPYERVVLREASF-------KRPVVILGPV---ADIAMQKLT 636
Query 501 NKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSI 560
+ D+F A T SR D + K I+ +
Sbjct 637 AEMPDQFEIA---ETVSRTD--------------------SPSKIIK------------L 661
Query 561 DSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEE 620
D+VR + K LL + +++ L P ++F P S+ L+AL +
Sbjct 662 DTVRVIAEKDKHALLDVTPSAIERLNYVQYYPIVVFFIPESRPALKALRQWLAPASR-RS 720
Query 621 LREIIEKTREMEQNNGHYFDTAI-VNSDLDKAYQELLRLINKLDTEPQWV 669
R + + +++ +++ H F I +N D YQEL +I + T P W
Sbjct 721 TRRLYAQAQKLRKHSSHLFTATIPLNGTSDTWYQELKAIIREQQTRPIWT 770
Score = 54.7 bits (130), Expect = 3e-06, Method: Composition-based stats.
Identities = 20/86 (23%), Positives = 40/86 (47%), Gaps = 3/86 (3%)
Query 248 QYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
+ VK V +++ G + ++ + I I G A + L EGD +L+ING+
Sbjct 187 DVQMKPVKSVLVKRRDSEEFGVKLGSQ---IFIKHITDSGLAARHRGLQEGDLILQINGV 243
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLI 333
+ +N+ L+ G L+ +++
Sbjct 244 SSQNLSLNDTRRLIEKSEGKLSLLVL 269
Score = 52.0 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 18/87 (21%), Positives = 34/87 (39%), Gaps = 2/87 (2%)
Query 260 EKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFD 319
+ I + S+++S +V GG AE G L GD ++ +NG+ +
Sbjct 19 RRGFGIAISGGRDRPGGSMVVSDVVPGGPAE--GRLQTGDHIVMVNGVSMENATSAFAIQ 76
Query 320 LLSDMHGTLTFVLIPSQQIKPPPAKET 346
+L + ++I P K +
Sbjct 77 ILKTCTKMANITVKRPRRIHLPATKAS 103
>sp|Q2NQS9|KGUA_SODGM Guanylate kinase OS=Sodalis glossinidius
(strain morsitans) OX=343509 GN=gmk PE=3 SV=1
Length=207
Score = 253 bits (645), Expect = 8e-79, Method: Composition-based stats.
Identities = 52/187 (28%), Positives = 85/187 (45%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + ++ HTTR+ R E G+ Y FV F
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSISHTTRAMRPGEAHGQHYFFVPVAEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
E IA F+E+ N YGTS ++++QV+ +G L + Q + +R IF
Sbjct 63 EHMIAEDAFLEYARVFDNYYGTSREAIQQVLATGVDVFLDIDWQGAQQIRAKMPDARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+ PPS+E L L ++ + R + + EM + +D IVN D + A +L
Sbjct 123 VLPPSKEELDRRLRGRDQDSEEVIGRRMAQAVAEM--THFAEYDYLIVNDDFNTALLDLK 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRAER 187
>sp|Q15Z10|KGUA_PSEA6 Guanylate kinase OS=Pseudoalteromonas atlantica
(strain T6c / ATCC BAA-1087) OX=3042615 GN=gmk PE=3
SV=1
Length=215
Score = 253 bits (645), Expect = 8e-79, Method: Composition-based stats.
Identities = 58/202 (29%), Positives = 91/202 (45%), Gaps = 10/202 (5%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEK------DRFASAVPHTTRSRRDQEVAGRD 527
P + IL P G++ L + L+ + +V HTTR+ R E+ G
Sbjct 1 MPQSLGNLFILAAPSGAGKSSLIKALLQNHDATEIHNNEMQVSVSHTTRAPRPGEIDGVH 60
Query 528 YHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN 587
YHFVSR+ F+ I +F E E N YGTS + Q + G L + Q + ++
Sbjct 61 YHFVSRKVFQELITQDEFFEWAEVFGNYYGTSKVVIEQTLRKGIDVFLDIDWQGARQVKA 120
Query 588 SDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD 647
IF+APPS+E L L + G++ + + E+ ++ H FD +VN D
Sbjct 121 QIPDTATIFVAPPSREELMRRLTERGQDTPEVIQDRMNKAVSEI--SHYHEFDYIVVNDD 178
Query 648 LDKAYQELLRLIN--KLDTEPQ 667
A EL +++ +L E Q
Sbjct 179 FTAALAELDAIVSSRRLRKEKQ 200
>sp|Q4QJK3|KGUA_HAEI8 Guanylate kinase OS=Haemophilus influenzae
(strain 86-028NP) OX=281310 GN=gmk PE=3 SV=1
Length=208
Score = 252 bits (643), Expect = 1e-78, Method: Composition-based stats.
Identities = 50/192 (26%), Positives = 87/192 (45%), Gaps = 4/192 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFA-SAVPHTTRSRRDQEVAGRDYHFVSRQA 535
++ IL P G++ L L+ + +V HTTR+ R EV G Y+FVS++
Sbjct 2 SQGNLYILSAPSGAGKSSLISALLASDSSTQKMVSVSHTTRAPRPGEVEGVHYYFVSKEE 61
Query 536 FEADIAAGKFIEHGEFEK-NLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
FE+ I F+E+ + N YGTS+ ++ + + G L + Q + +R
Sbjct 62 FESLIEQDLFLEYAKVFGGNYYGTSLPAIEENLAKGIDVFLDIDWQGAQQIRKKVPSVKS 121
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFI PPS L L G++ + + + E+ ++ +D IVN D +K ++
Sbjct 122 IFILPPSLPELERRLIGRGQDSEEVIAERMSKAISEI--SHYDEYDYVIVNDDFEKTLKD 179
Query 655 LLRLINKLDTEP 666
L ++
Sbjct 180 LQSILQSERLTK 191
>sp|Q8K9C7|KGUA_BUCAP Guanylate kinase OS=Buchnera aphidicola
subsp. Schizaphis graminum (strain Sg) OX=198804 GN=gmk PE=3
SV=1
Length=207
Score = 251 bits (640), Expect = 4e-78, Method: Composition-based stats.
Identities = 50/184 (27%), Positives = 87/184 (47%), Gaps = 3/184 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMN-KEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
++ I+ P G++ L + L+ K ++ HTTR R E G+ Y+F+S++
Sbjct 2 SQGILFIISAPSGTGKSSLIEGLLKTKFLYNIQVSISHTTRVMRPGESHGKHYYFISKKE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F I F+E+ + N YGTS S+ +++ SG L + Q +R I
Sbjct 62 FRIMIKQESFLEYAKVFNNYYGTSRQSIEKMLLSGIDVFLDIDWQGANQIRYKMPNSKSI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PPS++ L L + G++ + + + EM N+ +D I+N D KA +L
Sbjct 122 FLLPPSKDELYKRLRERGQDSDTVISKRMEKAVDEM--NHYSEYDYLIINDDFQKAINDL 179
Query 656 LRLI 659
+I
Sbjct 180 RTII 183
>sp|O62683|ZO3_CANLF Tight junction protein ZO-3 OS=Canis lupus
familiaris OX=9615 GN=TJP3 PE=1 SV=1
Length=898
Score = 269 bits (688), Expect = 8e-78, Method: Composition-based stats.
Identities = 89/474 (19%), Positives = 171/474 (36%), Gaps = 86/474 (18%)
Query 225 DKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIV 284
D + + + E G ++VR K I L N++ + +S +
Sbjct 343 DAPRHSSYDIYRVPSSQSAEDRGYSP--DSRVVRFHKGTTIGLRLAGGNDV-GIFVSGVQ 399
Query 285 KGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD--MHGTLTFVLIPSQQIKPPP 342
+G A+ G + EGD++L++N + R E L + V ++ I
Sbjct 400 EGSPADGQG-IQEGDQILQVNDVPFRNLTREEAVQFLVALPPGEEVELVTQRNEDIFRKM 458
Query 343 AKET---VIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPN---------WW 390
+ +++ HF+ + S GL F +GD+ HV+ P W
Sbjct 459 VQSRVGDSFYIRTHFELEASPPS-------GLGFTRGDVFHVLDTLCPGPGPSGARGTHW 511
Query 391 QAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIE-------EDKEPEKSGKLW------- 436
A R G + + G++P +S +Q +++ + W
Sbjct 512 LAVRMGRDLREQERGIIPNQSRAEQLASLESAQRAVGAGPGASVGSSARAEFWRLRGLRR 571
Query 437 CAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELR 496
AKK+ ++ ++ L + Y E + E S KRP++++GP +
Sbjct 572 GAKKSTQRSREDLSALTRQGHYPPYERVVLREASF-------KRPVVILGPV---ADIAM 621
Query 497 QRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLY 556
Q+L + D+F A R+ ++
Sbjct 622 QKLTAEMPDQFGIADS-VLRTDSPSKI--------------------------------- 647
Query 557 GTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNP 616
+D+VR + K LL + +++ L P ++F AP S+ L+AL
Sbjct 648 -IKLDTVRVIAEKNKHALLDVTPSAVERLNYVQYYPIVVFCAPESRAALKALRQWLAPAS 706
Query 617 KPEELREIIEKTREMEQNNGHYFDTAI-VNSDLDKAYQELLRLINKLDTEPQWV 669
+ R + + +++ +++ H F I + D YQEL ++ + T P W
Sbjct 707 R-RSARRLYAQAQKLRKHSEHLFTATIPLRGTSDTWYQELKAVVREQQTRPIWT 759
Score = 57.8 bits (138), Expect = 3e-07, Method: Composition-based stats.
Identities = 21/86 (24%), Positives = 39/86 (45%), Gaps = 3/86 (3%)
Query 248 QYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
VK V + + G T+ ++ + I I G A ++ L EGD +L+ING+
Sbjct 179 DVHMRPVKSVLVRRTESEEFGVTLGSQ---IFIKHITDSGLAARNRGLQEGDLILQINGV 235
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLI 333
+++ L+ G LT +++
Sbjct 236 SSENLSLSDTRRLIEKSEGKLTLLVL 261
Score = 35.0 bits (79), Expect = 2.6, Method: Composition-based stats.
Identities = 12/60 (20%), Positives = 22/60 (37%), Gaps = 2/60 (3%)
Query 288 AAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV 347
A+ G L GD V+ +NG+ + +L + ++I+ P K
Sbjct 47 PAD--GRLQTGDHVVMVNGVSMESVTSTFAIQILKTCTKLANITVKRPRKIQLPATKAGT 104
>sp|Q65JT0|KGUA_BACLD Guanylate kinase OS=Bacillus licheniformis
(strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC
12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46)
OX=279010 GN=gmk PE=3 SV=1
Length=204
Score = 249 bits (637), Expect = 9e-78, Method: Composition-based stats.
Identities = 52/183 (28%), Positives = 85/183 (46%), Gaps = 2/183 (1%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R I+L GP G+ +RQ L +E +F ++ TTR R E G DY F +R+ F
Sbjct 3 ERGLLIVLSGPSGVGKGTVRQALFAQEDTKFEYSISVTTRKPRQGERDGVDYFFKTREEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
E I K +E E+ N YGT +D V Q + SG+ L + Q +R + + IF
Sbjct 63 EEMIENNKLLEWAEYVGNYYGTPVDYVEQTLESGRDVFLEIEVQGALQVRKAFPEGLFIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+APPS L+ + G + + E+E + +D + N ++ A + +
Sbjct 123 LAPPSLAELKNRIVTRGTETEATIENRMKAAKEEIELMDA--YDYVVENDSIELACERIK 180
Query 657 RLI 659
++
Sbjct 181 AIV 183
>sp|P57888|KGUA_PASMU Guanylate kinase OS=Pasteurella multocida
(strain Pm70) OX=272843 GN=gmk PE=3 SV=1
Length=208
Score = 250 bits (638), Expect = 9e-78, Method: Composition-based stats.
Identities = 50/188 (27%), Positives = 87/188 (46%), Gaps = 4/188 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ IL P G++ L L+N+++D + +V HTTR R E G Y+FVS +AF
Sbjct 3 QGNLYILSAPSGAGKSSLISALLNQQQDNKMMVSVSHTTRQPRPGEQEGVHYYFVSVEAF 62
Query 537 EADIAAGKFIEHGEFEK-NLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
E+ I F+E+ + N YGTS+ ++ + + G L + Q + +R I
Sbjct 63 ESLIEQDLFLEYAKVFGGNYYGTSLPAIEENLAKGIDVFLDIDWQGAQQIRQKVPNVKSI 122
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS L L G++ + + E+ ++ + +D IVN ++A +
Sbjct 123 FILPPSLAELERRLIGRGQDSTEVIAARMSKAIDEI--SHYNEYDYVIVNDVFEQALADF 180
Query 656 LRLINKLD 663
++
Sbjct 181 QAILRAER 188
>sp|E9Q9R9|DLG5_MOUSE Disks large homolog 5 OS=Mus musculus OX=10090
GN=Dlg5 PE=1 SV=1
Length=1921
Score = 274 bits (701), Expect = 1e-77, Method: Composition-based stats.
Identities = 100/574 (17%), Positives = 226/574 (39%), Gaps = 83/574 (14%)
Query 128 FSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQ 187
S Q L+ Q + I++L Q N H+ + H++ A+ P + +
Sbjct 1402 LRSATEQQARLIIGQQCDTITILAQ--YNPHIHQL-NSHSRSSSHLDPAATPHSTLQGSS 1458
Query 188 DLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIG 247
E +V+ P+ ++ TP + + V + +
Sbjct 1459 AGTPEHPSVIDPLMEQDEGP-----GTPPAKQSASSTRSVGDTTKKTPDP---------- 1503
Query 248 QYGGETVKIVRIEKARDIPLGA-TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEING 306
+IV I+K++ + LG + V ++ + A+ L GD +LE
Sbjct 1504 -------RIVFIKKSQ-LDLGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGS 1555
Query 307 IEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ--IKPPPAKETVIHVKAHFDYDPSDDPYV 364
+++R + V +V+ + +L + + + +++A +D +
Sbjct 1556 LDMRSRTVEDVYVEMLKPKDSLRLKVQYRHEEFTRVKGLPGDSFYIRALYDR-------L 1608
Query 365 PCRELGLSFQKGDILHV---ISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQ 421
E LSF+K DIL+V + Q W A++ + + G +P K Q + +
Sbjct 1609 AEVEPELSFKKDDILYVDDTLPQGVFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRL 1668
Query 422 TIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKN---------DDYDNEEILTYEE-MSL 471
++ E K+ + L A + R+K + + + D + N+ I +E+ +SL
Sbjct 1669 SMSEVKDDNTAKTLSAAARRSFFRRKHKHKRSGSKDGKDLLALDTFSNDSIPLFEDSVSL 1728
Query 472 YHQPANRK-----RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGR 526
+Q + RP++L+GP + +++ L+N+ +F ++
Sbjct 1729 AYQRVQKVDCTSLRPVLLLGPL---LDVVKEMLVNEAPGKFCRCPLEVMKA--------- 1776
Query 527 DYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLR 586
S+QA E + F+++ + T++ S++++ + CLL + +++ L
Sbjct 1777 -----SQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNRHCLLDIAPHAIERLH 1831
Query 587 NSDLKPYIIFIAPPSQERLRALLAKEGKNP-------KPEELREIIEKTREMEQNNGHYF 639
+ + P +IFI S + ++ ++P +E E ++++Q YF
Sbjct 1832 HMHIYPIVIFIRYKSAKHIKE-----QRDPVYLRDKVTQRHSKEQFETAQKIDQEYSRYF 1886
Query 640 DTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTW 673
+ L ++L ++++ ++ W+P+
Sbjct 1887 TGVVQGGALSSICTQILAMVSQEQSKVLWIPACP 1920
Score = 62.8 bits (151), Expect = 1e-08, Method: Composition-based stats.
Identities = 29/138 (21%), Positives = 57/138 (41%), Gaps = 8/138 (6%)
Query 226 KVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV-RNEMDSVIISRIV 284
A ++ + E + V+++K + PLG ++ E V +S++
Sbjct 1320 TTASTLPRIAVNPSSHGERRKDRPFVEEPRHVKVQKGSE-PLGISIVSGEKGGVYVSKVT 1378
Query 285 KGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAK 344
G A ++G L GD++LE NGI +R + ++ T+T + + P
Sbjct 1379 LGSIAHQAG-LEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYN-----PHIH 1432
Query 345 ETVIHVKAHFDYDPSDDP 362
+ H ++ DP+ P
Sbjct 1433 QLNSHSRSSSHLDPAATP 1450
Score = 57.8 bits (138), Expect = 3e-07, Method: Composition-based stats.
Identities = 32/126 (25%), Positives = 49/126 (39%), Gaps = 17/126 (13%)
Query 256 IVRIEKARD----IPLGATVRNEMD-------SVIISRIVKGGAAEKSGLLHEGDEVLEI 304
+VR K+ PL + + D V + +V G A K G L GD ++ I
Sbjct 705 VVRRRKSLGGKVVTPLHINLSGQKDSGISLENGVYAAAVVPGSPAAKEGSLAVGDRIVAI 764
Query 305 NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYV 364
NGI + K +NE LL +LT L+ + + + F+ D +
Sbjct 765 NGIALDNKSLNECESLLRSCQDSLTLSLLKVFP------QSSSWSGQNIFENIKDSDRML 818
Query 365 PCRELG 370
CR G
Sbjct 819 SCRAHG 824
>sp|Q1QSI1|KGUA_CHRSD Guanylate kinase OS=Chromohalobacter salexigens
(strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB
13768 / 1H11) OX=290398 GN=gmk PE=3 SV=1
Length=215
Score = 249 bits (637), Expect = 1e-77, Method: Composition-based stats.
Identities = 60/192 (31%), Positives = 95/192 (49%), Gaps = 3/192 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
QP ++ I+ P G+ L + L+ + +V HTTR+ R E G +YHFV
Sbjct 4 QPPSKGTLYIVSAPSGAGKTSLVRALLERVAG-IQVSVSHTTRAMRPGEQNGINYHFVDV 62
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
FE I +G FIEH N YGTS +V+ ++++G+ +L + Q + +R + +
Sbjct 63 ATFERLIESGDFIEHARVFDNYYGTSRAAVQALLDAGQDVILEIDWQGARQVREAFDEAV 122
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI PPS+E L A LA G + R + + EM ++ ++ I+N D A
Sbjct 123 SIFILPPSREALHARLAGRGTDDAATIARRMRDAVDEM--SHYDEYEHVIINDTFDHALD 180
Query 654 ELLRLINKLDTE 665
EL L++ T
Sbjct 181 ELSCLVHAQRTR 192
>sp|Q88C87|KGUA_PSEPK Guanylate kinase OS=Pseudomonas putida (strain
ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
OX=160488 GN=gmk PE=3 SV=1
Length=206
Score = 249 bits (636), Expect = 2e-77, Method: Composition-based stats.
Identities = 58/185 (31%), Positives = 88/185 (48%), Gaps = 3/185 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
I+ P G+ L L K+ + +V HTTR+ R E G +YHFV + F+A
Sbjct 6 GTLYIVSAPSGAGKTSLVTAL-TKDDQQIRVSVSHTTRAMRPGEQHGVNYHFVVHEEFKA 64
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
IA G F+EH E N YGTS +++Q ++ G +L + Q + +R + +FI
Sbjct 65 LIAQGDFLEHAEVFGNFYGTSRSALQQTLDQGYDLILEIDWQGAQQVRKLMPQALSVFIL 124
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPSQE LR L G++ + + E EM + +D I+N D D A +L +
Sbjct 125 PPSQEALRHRLDGRGQDSEEIIAGRMKEAVSEM--VHYDEYDYVIINDDFDTALADLKAV 182
Query 659 INKLD 663
Sbjct 183 FRSNR 187
>sp|Q5F775|KGUA_NEIG1 Guanylate kinase OS=Neisseria gonorrhoeae
(strain ATCC 700825 / FA 1090) OX=242231 GN=gmk PE=3 SV=1
Length=205
Score = 248 bits (634), Expect = 2e-77, Method: Composition-based stats.
Identities = 60/184 (33%), Positives = 93/184 (51%), Gaps = 3/184 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ G+ L RL+ + +V HTTR R+ E G YHFVS++ F
Sbjct 5 RKGNIFIISAASGTGKTTLVSRLLANH-NGLRVSVSHTTRPPREGEANGVHYHFVSKEEF 63
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
E+ IA F+E+ + N YGTS + V + +G +L + Q +RN+ + IF
Sbjct 64 ESLIAQEAFLEYADVFGNYYGTSTEGVNALAAAGYDVILEIDVQGAAQVRNALPEAVGIF 123
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS + L A L G + + R + + E+EQ+ FD +VN DL+KA +LL
Sbjct 124 ILPPSFDVLAARLKGRGTDSREVIQRRLSKARHEIEQSV--LFDFVVVNDDLEKAEGDLL 181
Query 657 RLIN 660
++N
Sbjct 182 HIVN 185
>sp|Q67PR9|KGUA_SYMTH Guanylate kinase OS=Symbiobacterium thermophilum
(strain T / IAM 14863) OX=292459 GN=gmk PE=3 SV=1
Length=211
Score = 248 bits (634), Expect = 3e-77, Method: Composition-based stats.
Identities = 55/182 (30%), Positives = 87/182 (48%), Gaps = 3/182 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ I++ GP G+ + + L+ + +V TTR +R EV G +Y+F+S++ FE
Sbjct 6 KGLLIVVTGPSAVGKGTICRALLAETPG-IRFSVSCTTRPKRPGEVDGVEYYFISKEEFE 64
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
IAAG+F+E E N YGT V +V G+ +L + + +R +F+
Sbjct 65 RRIAAGEFLEWAEVYGNYYGTPRGYVEEVTAQGQDVILDIDRVGARAVREQYPDAVSVFV 124
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS E LR +A G R + E + + +D IVN DL +A EL
Sbjct 125 IPPSMEALRQRIAARGTESPEAVARRLAEAPEWIREGLT--YDYVIVNDDLARAVAELRA 182
Query 658 LI 659
+I
Sbjct 183 II 184
>sp|Q89AC8|KGUA_BUCBP Guanylate kinase OS=Buchnera aphidicola
subsp. Baizongia pistaciae (strain Bp) OX=224915 GN=gmk PE=3
SV=1
Length=207
Score = 248 bits (633), Expect = 4e-77, Method: Composition-based stats.
Identities = 51/184 (28%), Positives = 87/184 (47%), Gaps = 3/184 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDR-FASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+N +V HTTR R E G+ Y+F+S F
Sbjct 3 KGLLFIVSAPSGTGKSSLIQALVNTHPLYSIKVSVSHTTRIIRPGECHGKHYYFISNTEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I +F+E+ + N YGTS + +++G L + Q + +RN + IF
Sbjct 63 QNMIDKEEFLEYAKVFNNYYGTSKKQINYGLSTGTDVFLDIDWQGARQIRNKLPESKSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+E L L K G++ + + + EM+ +D I+N + + A +L
Sbjct 123 ILPPSKEELYRRLCKRGQDSDIIIKKRMNQAVSEMKHYI--DYDYLIINDNFNLAVSDLY 180
Query 657 RLIN 660
++I
Sbjct 181 KIIR 184
>sp|Q5P3M0|KGUA_AROAE Guanylate kinase OS=Aromatoleum aromaticum
(strain EbN1) OX=76114 GN=gmk PE=3 SV=2
Length=204
Score = 248 bits (633), Expect = 4e-77, Method: Composition-based stats.
Identities = 57/188 (30%), Positives = 87/188 (46%), Gaps = 3/188 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
II+ P G+ L L+ ++ + +V +TTR R E GR+YHFV F A
Sbjct 3 GTLIIITAPSGAGKTTLVSGLLERDP-QVNLSVSYTTREPRPGERDGREYHFVDVATFRA 61
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
G+F+E E N Y TS ++Q I +G+ LL + Q + +R S +FI
Sbjct 62 LRDRGEFLEWAEVHGNYYATSKVWLKQQIATGRDILLEIDWQGAQQVRKSFPDAVGVFIL 121
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS E L A L G + +R ++ EM + FD I+N+DL A +L+ +
Sbjct 122 PPSLEELEARLRGRGTDSDDVIMRRLLGARGEMR--HVGEFDYVILNNDLQCALDDLVAV 179
Query 659 INKLDTEP 666
+
Sbjct 180 VRASRLRY 187
>sp|Q47UB3|KGUA_COLP3 Guanylate kinase OS=Colwellia psychrerythraea
(strain 34H / ATCC BAA-681) OX=167879 GN=gmk PE=3 SV=1
Length=218
Score = 248 bits (634), Expect = 4e-77, Method: Composition-based stats.
Identities = 52/189 (28%), Positives = 84/189 (44%), Gaps = 6/189 (3%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDR----FASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
IL P G++ L L+ + ++ HTTR R E G YHFVS +
Sbjct 5 GNLFILSAPSGAGKSSLINALLKPDNQASARAMQVSISHTTRDARPGENNGEHYHFVSVE 64
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
F+ I+ F E+ E N YGTS ++ ++ G L + Q + +R
Sbjct 65 EFKKQISLNAFYEYAEVFGNYYGTSEAAIDAQLSQGIDVFLDIDWQGAQQVRMKKPGVTT 124
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFI+PPS+E L + L G++ + + E ++ + FD IVN D ++A +
Sbjct 125 IFISPPSKEELESRLRGRGQDSDEVIASRMAQAQA--ECSHYNEFDYVIVNDDFEQALLD 182
Query 655 LLRLINKLD 663
L ++N
Sbjct 183 LTTIVNNQR 191
>sp|Q64520|KGUA_MOUSE Guanylate kinase OS=Mus musculus OX=10090
GN=Guk1 PE=1 SV=2
Length=198
Score = 247 bits (631), Expect = 7e-77, Method: Composition-based stats.
Identities = 70/190 (37%), Positives = 108/190 (57%), Gaps = 1/190 (1%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
RP++L GP G++ L ++L + F +V HTTR+ R E G+DY+FV+R+ +
Sbjct 4 PRPVVLSGPSGAGKSTLLKKLFQEHSSIFGFSVSHTTRNPRPGEEDGKDYYFVTREMMQR 63
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
DIAAG FIEH EF NLYGTS ++VR V +IC+L + Q +++++ +DL P IF+
Sbjct 64 DIAAGDFIEHAEFSGNLYGTSKEAVRAVQAMNRICVLDVDLQGVRSIKKTDLCPIYIFVQ 123
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQN-NGHYFDTAIVNSDLDKAYQELLR 657
PPS + L L + + + +ME + FD I+N DLDKAY L +
Sbjct 124 PPSLDVLEQRLRLRNTETEESLAKRLAAARTDMESSKEPGLFDLVIINDDLDKAYATLKQ 183
Query 658 LINKLDTEPQ 667
+++ + Q
Sbjct 184 ALSEEIKKAQ 193
>sp|Q1GNB4|KGUA_SPHAL Guanylate kinase OS=Sphingopyxis alaskensis
(strain DSM 13593 / LMG 18877 / RB2256) OX=317655 GN=gmk
PE=3 SV=1
Length=220
Score = 248 bits (633), Expect = 7e-77, Method: Composition-based stats.
Identities = 44/188 (23%), Positives = 82/188 (44%), Gaps = 4/188 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R +L P G+ + + ++ ++KD A +V TTR R E+ G YHFV F
Sbjct 9 RRGVLFVLSSPSGAGKTTISRMMLEEDKD-IALSVSATTRPPRPGEIDGVHYHFVDTDTF 67
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTL-RNSDLKPYII 595
+ A G F+E + YGT V +++ +GK L + Q + L + + +
Sbjct 68 KKMAADGAFLEWAHVFGHRYGTPRAPVEELLAAGKDVLFDIDWQGAQQLYQEAGPDVVRV 127
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP+ E L L G + + E+ ++ +D ++N + + Y E+
Sbjct 128 FVLPPTMEELERRLRARGTDSDEVIAARMARAANEI--SHWDGYDYVLINDHVGECYGEV 185
Query 656 LRLINKLD 663
+ ++
Sbjct 186 MAILRAER 193
>sp|Q2S8R2|KGUA_HAHCH Guanylate kinase OS=Hahella chejuensis (strain
KCTC 2396) OX=349521 GN=gmk PE=3 SV=1
Length=208
Score = 247 bits (631), Expect = 9e-77, Method: Composition-based stats.
Identities = 56/186 (30%), Positives = 85/186 (46%), Gaps = 3/186 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R + I+ P G+ L L+ ++K ++ HTTR R E G +Y F+SR+ F
Sbjct 3 RGQLYIISAPSGAGKTSLVSALLKEDKLA-QVSISHTTRQVRPGEQDGVNYFFISREEFL 61
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
A AG F+EH E N YGTS V + G +L + Q + +R + IFI
Sbjct 62 AQAQAGDFLEHAEVFGNFYGTSQAWVESTLAKGVDVILEIDWQGAQQVRKLRPEAKSIFI 121
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS E L+ L G++ R + E E+ ++ +D + N D D A +EL
Sbjct 122 LPPSLEALQQRLESRGQDSAEVIQRRLQEAANEI--SHYPEYDYLVFNDDFDHALEELKS 179
Query 658 LINKLD 663
+
Sbjct 180 VFRAER 185
>sp|Q82ZD5|KGUA_ENTFA Guanylate kinase OS=Enterococcus faecalis
(strain ATCC 700802 / V583) OX=226185 GN=gmk PE=3 SV=1
Length=204
Score = 246 bits (628), Expect = 2e-76, Method: Composition-based stats.
Identities = 55/184 (30%), Positives = 94/184 (51%), Gaps = 2/184 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+L GP G+ +R+ + + E++ F ++ TTR +R+ EV G DY+F SR+
Sbjct 2 SERGLLIVLSGPSGVGKGTVRKAIFDSEENDFQYSISMTTRKQREGEVDGVDYYFRSREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FEA I AG+ +E+ E+ N YGT + V Q ++ GK L + Q K +++ I
Sbjct 62 FEAMIEAGEMLEYAEYVGNYYGTPLTYVNQTLDEGKDVFLEIEVQGAKQVKDKVPDGVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP L++ + G + + E+E +D A+VN ++ A Q +
Sbjct 122 FLTPPDLAELKSRIIGRGTDEMSVIEERMAVAREEIEMMA--LYDYAVVNDEVPLAVQRI 179
Query 656 LRLI 659
+I
Sbjct 180 KDII 183
>sp|Q0A5V3|KGUA_ALKEH Guanylate kinase OS=Alkalilimnicola ehrlichii
(strain ATCC BAA-1101 / DSM 17681 / MLHE-1) OX=187272
GN=gmk PE=3 SV=1
Length=203
Score = 246 bits (628), Expect = 2e-76, Method: Composition-based stats.
Identities = 55/187 (29%), Positives = 91/187 (49%), Gaps = 3/187 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
++ P G+ L L+ ++ + + +V HTTR R E G +YHFV R F+A
Sbjct 3 GTLYVVSAPSGAGKTSLVNALVRQD-EAVSLSVSHTTRPPRPGEEDGVNYHFVDRDRFQA 61
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+A G F+EH E N YGTS +V+ +++ G+ +L + Q + +R +FI
Sbjct 62 LVAQGDFLEHAEVFGNHYGTSRSAVQALLDQGQDVILEIDWQGARQVRERMPGCLSVFIL 121
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS+E LR L + G++ R + E EM ++ +D +VN D D+ +L +
Sbjct 122 PPSREELRRRLTQRGQDEPEVIDRRMAEAVSEM--SHYAEYDYLLVNDDFDRTLADLQAI 179
Query 659 INKLDTE 665
Sbjct 180 FTANRHR 186
>sp|Q9JT96|KGUA_NEIMA Guanylate kinase OS=Neisseria meningitidis
serogroup A / serotype 4A (strain DSM 15465 / Z2491) OX=122587
GN=gmk PE=3 SV=1
Length=205
Score = 245 bits (625), Expect = 6e-76, Method: Composition-based stats.
Identities = 57/184 (31%), Positives = 92/184 (50%), Gaps = 3/184 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ G+ L RL+ + +V HTTR R+ E G YHFVS++ F
Sbjct 5 RKGNIFIISAASGTGKTTLVSRLLANH-NGLRVSVSHTTRPPREGEANGVHYHFVSKEEF 63
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
E+ IA F+E+ + N YGTS + V + +G +L + Q +R++ + IF
Sbjct 64 ESLIAQEAFLEYADVFGNYYGTSAEGVNALAAAGYDVILEIDVQGAAQVRDALPEAVGIF 123
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS + L A L G + + R + + E+EQ+ FD +VN DL +A ++L
Sbjct 124 ILPPSFDVLAARLNGRGTDSREVIQRRLSKARHEIEQSV--LFDFVVVNDDLARAEEDLR 181
Query 657 RLIN 660
++N
Sbjct 182 HIVN 185
>sp|Q7VKP3|KGUA_HAEDU Guanylate kinase OS=Haemophilus ducreyi
(strain 35000HP / ATCC 700724) OX=233412 GN=gmk PE=3 SV=1
Length=206
Score = 245 bits (625), Expect = 7e-76, Method: Composition-based stats.
Identities = 49/192 (26%), Positives = 77/192 (40%), Gaps = 5/192 (3%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEK-DRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
IL P G++ L L+ ++ HTTR R E G Y+F FE
Sbjct 3 GNLYILSAPSGAGKSSLINALLADLPRTEVQLSISHTTRQPRVGETHGIHYYFTEHHEFE 62
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
+ I G F+E + YGTS+ + + + G L + Q + +R IFI
Sbjct 63 SLIEQGHFLEWARVFDHYYGTSLPMIERSLAQGIDVFLDIDWQGARQIREKVPNVKTIFI 122
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS+ L L G++ + + + EM + + FD I+N A EL
Sbjct 123 LPPSRAELEKRLVGRGQDSLETIAKRMEQAVSEM--THYNEFDYVIINDQFKTALTELKS 180
Query 658 LI--NKLDTEPQ 667
++ +L Q
Sbjct 181 ILTAERLKQSAQ 192
>sp|Q7NRL1|KGUA_CHRVO Guanylate kinase OS=Chromobacterium violaceum
(strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614
/ NCIMB 9131 / NCTC 9757) OX=243365 GN=gmk PE=3 SV=1
Length=210
Score = 245 bits (625), Expect = 8e-76, Method: Composition-based stats.
Identities = 55/191 (29%), Positives = 90/191 (47%), Gaps = 5/191 (3%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
I++ P G+ L L+ E ++ ++TR R E+ G+ YHF+ R AFE
Sbjct 6 GNIYIVVAPSGAGKTSLVAALLQAEPS-VELSISYSTRQARKGEIDGQHYHFIDRAAFEE 64
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
G F+E E N YGTS +R + +G+ LL + Q + +R IFIA
Sbjct 65 MKDRGDFLEWAEVYGNCYGTSAPWIRGRLEAGRDILLEIDWQGAEQVRKVFPDAIGIFIA 124
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS E L L + + LR + E+++ +D +VN D ++A +L+ +
Sbjct 125 PPSIEELERRLRGRDTDTEEVILRRLASARAEIDKIA--EYDYIVVNDDFERARLDLISI 182
Query 659 I--NKLDTEPQ 667
+ +L + PQ
Sbjct 183 VRAQRLRSAPQ 193
>sp|P15454|KGUA_YEAST Guanylate kinase OS=Saccharomyces cerevisiae
(strain ATCC 204508 / S288c) OX=559292 GN=GUK1 PE=1 SV=2
Length=187
Score = 244 bits (622), Expect = 9e-76, Method: Composition-based stats.
Identities = 68/181 (38%), Positives = 101/181 (56%), Gaps = 1/181 (1%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
RPI++ GP G++ L ++L + D F +V TTR+ R EV G+DY+FVS F++
Sbjct 3 RPIVISGPSGTGKSTLLKKLFAEYPDSFGFSVSSTTRTPRAGEVNGKDYNFVSVDEFKSM 62
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS-DLKPYIIFIA 598
I +FIE +F N YG+++ SV+QV SGK C+L + Q +K+++ +L +FIA
Sbjct 63 IKNNEFIEWAQFSGNYYGSTVASVKQVSKSGKTCILDIDMQGVKSVKAIPELNARFLFIA 122
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS E L+ L G + + + E+ D IVN DLDKAY+EL
Sbjct 123 PPSVEDLKKRLEGRGTETEESINKRLSAAQAELAYAETGAHDKVIVNDDLDKAYKELKDF 182
Query 659 I 659
I
Sbjct 183 I 183
>sp|Q24TX4|KGUA_DESHY Guanylate kinase OS=Desulfitobacterium hafniense
(strain Y51) OX=138119 GN=gmk PE=3 SV=1
Length=200
Score = 244 bits (623), Expect = 1e-75, Method: Composition-based stats.
Identities = 51/186 (27%), Positives = 84/186 (45%), Gaps = 3/186 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
N I+L GP G+ L Q L+ + + +V TTR R E+ G Y+F SR
Sbjct 1 MEQNHGLLIVLSGPSGAGKGTLCQELLRQLP-QVKYSVSATTRQPRPGEMDGLHYYFRSR 59
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ F+ I + +E EF N YGT +V Q I +G +L + Q ++ +
Sbjct 60 EEFQTMIEQDQLLEWAEFCGNYYGTPQFAVEQAIQAGNDVILEIEIQGALQVKQRFPQGV 119
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+ PPS + L + K G + + + RE+E +D +VN ++ A
Sbjct 120 FIFVVPPSMDELSQRIHKRGTESEEVIQKRLQTAARELE--YVSEYDYVVVNDEIPLAVD 177
Query 654 ELLRLI 659
+L ++
Sbjct 178 KLKSIL 183
>sp|Q8Z0I7|KGUA_NOSS1 Guanylate kinase OS=Nostoc sp. (strain PCC
7120 / SAG 25.82 / UTEX 2576) OX=103690 GN=gmk PE=3 SV=1
Length=199
Score = 244 bits (622), Expect = 1e-75, Method: Composition-based stats.
Identities = 61/196 (31%), Positives = 96/196 (49%), Gaps = 3/196 (2%)
Query 461 EEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRD 520
++L+ + + + + IIL GP G+ L + L+ + + + +V TTR R
Sbjct 2 MQVLSIQNCATTKENPLSGKLIILTGPSGVGKGTLMRSLLQRHPELY-YSVSATTRPPRP 60
Query 521 QEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQ 580
EV G Y+FVSR FE IA G+F+E EF N YGT ++V + SGK+ +L +
Sbjct 61 GEVNGESYYFVSRSKFEELIAQGEFLESAEFAGNYYGTPREAVLNQVQSGKLVVLEIELA 120
Query 581 SLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFD 640
+ +R S + IFI PPS E L + G++ + R + + + E FD
Sbjct 121 GARQIRTSFPEALSIFILPPSFEELENRIRGRGQDSEEAIARRL--QRAKEEIQAADEFD 178
Query 641 TAIVNSDLDKAYQELL 656
IVN D + A Q +
Sbjct 179 IQIVNDDFEAALQAIE 194
>sp|Q3K4L8|KGUA_PSEPF Guanylate kinase OS=Pseudomonas fluorescens
(strain Pf0-1) OX=205922 GN=gmk PE=3 SV=1
Length=206
Score = 244 bits (623), Expect = 1e-75, Method: Composition-based stats.
Identities = 56/199 (28%), Positives = 90/199 (45%), Gaps = 5/199 (3%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ I+ P G++ L + L + D ++ HTTR+ R EV G +YHFV+R
Sbjct 1 MTHSTGTLYIISAPSGAGKSSLVKALTDTNPD-IRVSISHTTRAMRPGEVDGVNYHFVTR 59
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ F G F+E E N YGTS ++Q ++ G +L + Q + +R +
Sbjct 60 EEFVKMGEHGDFLERAEVFGNFYGTSQSRLQQTLDEGHDLILEIDWQGAEQVRKLMPQAR 119
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI PPS + L L G++ + E EM ++ +D I+N D A
Sbjct 120 SIFILPPSLQALHQRLTNRGQDSDEIIDGRMREAVSEM--SHYVEYDYLIINDDFAHALD 177
Query 654 ELLRLI--NKLDTEPQWVP 670
+L + N+L + Q V
Sbjct 178 DLKAIFRANQLQQKRQQVR 196
>sp|Q3MD38|KGUA_TRIV2 Guanylate kinase OS=Trichormus variabilis
(strain ATCC 29413 / PCC 7937) OX=240292 GN=gmk PE=3 SV=1
Length=199
Score = 244 bits (622), Expect = 1e-75, Method: Composition-based stats.
Identities = 60/196 (31%), Positives = 99/196 (51%), Gaps = 3/196 (2%)
Query 461 EEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRD 520
++L+ + + + + + I+L GP G+ L + L+ + + + +V TTR+ R
Sbjct 2 MQVLSIQNCATTKENPSSGKLIVLTGPSGVGKGTLMRSLLQRHPELY-YSVSATTRAPRP 60
Query 521 QEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQ 580
EV G Y+F+SR FE +A G+F+E EF N YGT ++V I SGK+ +L +
Sbjct 61 GEVNGESYYFISRNKFEELLAQGEFLESAEFAGNYYGTPREAVLNQIQSGKLVVLEIELA 120
Query 581 SLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFD 640
+ +R S + IFI PPS E L + G++ + R + T E++ FD
Sbjct 121 GARQIRASFPEALSIFILPPSFEELEKRIRGRGQDSEEAIARRLQRATEEIQ--AADEFD 178
Query 641 TAIVNSDLDKAYQELL 656
IVN D + A Q +
Sbjct 179 IQIVNDDFEAALQAIE 194
>sp|Q9QXY1|ZO3_MOUSE Tight junction protein ZO-3 OS=Mus musculus
OX=10090 GN=Tjp3 PE=1 SV=1
Length=905
Score = 263 bits (673), Expect = 1e-75, Method: Composition-based stats.
Identities = 86/479 (18%), Positives = 171/479 (36%), Gaps = 91/479 (19%)
Query 225 DKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIV 284
+ E + + + E G ++V K I L N++ + +S +
Sbjct 342 ESPGESRYDIYRVPSRQSLEDRGYSP--DTRVVSFPKGASIGLRLAGGNDV-GIFVSGVQ 398
Query 285 KGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAK 344
G A+ G + EGDE+L++NG+ R E L + L+ + +
Sbjct 399 AGSPADGQG-IQEGDEILQVNGMPFRNLTREEAVQFLLGLPPGEDMELVTQSKTGHSLRR 457
Query 345 E------TVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNW--------- 389
+++ HF+ +PS GL F +GD+ HV+ P
Sbjct 458 WSQSRVGDSFYIRTHFELEPSPP-------YGLGFTRGDVFHVVDTLYPGSGPGHGHSSH 510
Query 390 ---WQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIE-------EDKEPEKSGKLWCAK 439
W A R G + + G++P +S +Q +++ + W +
Sbjct 511 GGLWLAARMGRDLREQERGVIPNQSRAEQLASLEAAQRAAGVGPGASVGSNPRAEFWRLR 570
Query 440 K--------NKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCG 491
+ ++ ++ L + Y E + E S KRP++++GP
Sbjct 571 SLRRGTKKASTQRSREDLSALTRQGHYPPYERVVLREASF-------KRPVVILGPV--- 620
Query 492 QNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEF 551
+ ++L + + F A +R+ ++
Sbjct 621 ADIAMKKLTTEMPEEFEIAESM-SRTDSPSKI---------------------------- 651
Query 552 EKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAK 611
+D+VR + K LL + +++ L P +IF AP S+ L+AL
Sbjct 652 ------IKLDTVRVIAERDKHALLDVTPSAIERLNYVQYYPIVIFCAPESRPALKALREW 705
Query 612 EGKNPKPEELREIIEKTREMEQNNGHYFDTAI-VNSDLDKAYQELLRLINKLDTEPQWV 669
+ R + + +++++++GH F I ++ D YQE+ +I + P W
Sbjct 706 LAPASR-RSSRRLYAQAQKLQKHSGHLFTATIPLHGTSDSWYQEVKAVIQQQQARPIWT 763
Score = 54.3 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 19/89 (21%), Positives = 40/89 (45%), Gaps = 3/89 (3%)
Query 248 QYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
+K V +++ G + ++ + I I + G A ++ L EGD +L+ING+
Sbjct 179 DVLMRPLKSVLVKRRNSEEFGVKLGSQ---IFIKHITESGLAARNHGLQEGDLILQINGV 235
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPSQ 336
+++ L+ G LT +++
Sbjct 236 SSANLSLSDTRRLIEKSEGELTLLVLRDS 264
Score = 39.7 bits (91), Expect = 0.11, Method: Composition-based stats.
Identities = 12/69 (17%), Positives = 26/69 (38%), Gaps = 0/69 (0%)
Query 292 SGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVK 351
G L GD ++ +NG+ + +L T + ++++ P K +
Sbjct 49 EGRLRTGDHIVMVNGVSVENVTSAFAIQILKTCTKTANVTVKRPRRVQLPATKASPASGH 108
Query 352 AHFDYDPSD 360
D + +D
Sbjct 109 QLSDQEEAD 117
>sp|Q8NX22|KGUA_STAAW Guanylate kinase OS=Staphylococcus aureus
(strain MW2) OX=196620 GN=gmk PE=3 SV=1
Length=207
Score = 244 bits (622), Expect = 2e-75, Method: Composition-based stats.
Identities = 56/187 (30%), Positives = 89/187 (48%), Gaps = 2/187 (1%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ I+L GP G+ +R+R+ + ++ TTR R+ EV G DY F +R
Sbjct 1 MDNEKGLLIVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFFKTR 60
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
AFEA I +FIE+ E+ N YGT + V+ ++ G L + + K +R
Sbjct 61 DAFEALIKDDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDAL 120
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+APPS E LR L G + I E +E+E N +D +VN +++ A
Sbjct 121 FIFLAPPSLEHLRERLVGRGTESDEKIQSRINEARKEVEMMN--LYDYVVVNDEVELAKN 178
Query 654 ELLRLIN 660
+ ++
Sbjct 179 RIQCIVE 185
>sp|Q6GA04|KGUA_STAAS Guanylate kinase OS=Staphylococcus aureus
(strain MSSA476) OX=282459 GN=gmk PE=3 SV=1
Length=207
Score = 244 bits (622), Expect = 2e-75, Method: Composition-based stats.
Identities = 56/187 (30%), Positives = 89/187 (48%), Gaps = 2/187 (1%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ I+L GP G+ +R+R+ + ++ TTR R+ EV G DY F +R
Sbjct 1 MDNEKGLLIVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFFKTR 60
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
AFEA I +FIE+ E+ N YGT + V+ ++ G L + + K +R
Sbjct 61 DAFEALIKDDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDAL 120
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+APPS E LR L G + I E +E+E N +D +VN +++ A
Sbjct 121 FIFLAPPSLEHLRERLVGRGTESDEKIQSRINEARKEVEMMN--LYDYVVVNDEVELAKN 178
Query 654 ELLRLIN 660
+ ++
Sbjct 179 RIQCIVE 185
>sp|Q5HGM3|KGUA_STAAC Guanylate kinase OS=Staphylococcus aureus
(strain COL) OX=93062 GN=gmk PE=1 SV=1
Length=207
Score = 244 bits (622), Expect = 2e-75, Method: Composition-based stats.
Identities = 56/187 (30%), Positives = 89/187 (48%), Gaps = 2/187 (1%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ I+L GP G+ +R+R+ + ++ TTR R+ EV G DY F +R
Sbjct 1 MDNEKGLLIVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFFKTR 60
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
AFEA I +FIE+ E+ N YGT + V+ ++ G L + + K +R
Sbjct 61 DAFEALIKDDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDAL 120
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+APPS E LR L G + I E +E+E N +D +VN +++ A
Sbjct 121 FIFLAPPSLEHLRERLVGRGTESDEKIQSRINEARKEVEMMN--LYDYVVVNDEVELAKN 178
Query 654 ELLRLIN 660
+ ++
Sbjct 179 RIQCIVE 185
>sp|Q2G1U0|KGUA_STAA8 Guanylate kinase OS=Staphylococcus aureus
(strain NCTC 8325 / PS 47) OX=93061 GN=gmk PE=3 SV=1
Length=207
Score = 244 bits (622), Expect = 2e-75, Method: Composition-based stats.
Identities = 56/187 (30%), Positives = 89/187 (48%), Gaps = 2/187 (1%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ I+L GP G+ +R+R+ + ++ TTR R+ EV G DY F +R
Sbjct 1 MDNEKGLLIVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFFKTR 60
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
AFEA I +FIE+ E+ N YGT + V+ ++ G L + + K +R
Sbjct 61 DAFEALIKDDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDAL 120
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+APPS E LR L G + I E +E+E N +D +VN +++ A
Sbjct 121 FIFLAPPSLEHLRERLVGRGTESDEKIQSRINEARKEVEMMN--LYDYVVVNDEVELAKN 178
Query 654 ELLRLIN 660
+ ++
Sbjct 179 RIQCIVE 185
>sp|Q2FHM9|KGUA_STAA3 Guanylate kinase OS=Staphylococcus aureus
(strain USA300) OX=367830 GN=gmk PE=3 SV=1
Length=207
Score = 244 bits (622), Expect = 2e-75, Method: Composition-based stats.
Identities = 56/187 (30%), Positives = 89/187 (48%), Gaps = 2/187 (1%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ I+L GP G+ +R+R+ + ++ TTR R+ EV G DY F +R
Sbjct 1 MDNEKGLLIVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFFKTR 60
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
AFEA I +FIE+ E+ N YGT + V+ ++ G L + + K +R
Sbjct 61 DAFEALIKDDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDAL 120
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+APPS E LR L G + I E +E+E N +D +VN +++ A
Sbjct 121 FIFLAPPSLEHLRERLVGRGTESDEKIQSRINEARKEVEMMN--LYDYVVVNDEVELAKN 178
Query 654 ELLRLIN 660
+ ++
Sbjct 179 RIQCIVE 185
>sp|Q4K3R4|KGUA_PSEF5 Guanylate kinase OS=Pseudomonas fluorescens
(strain ATCC BAA-477 / NRRL B-23932 / Pf-5) OX=220664 GN=gmk
PE=3 SV=1
Length=206
Score = 243 bits (621), Expect = 2e-75, Method: Composition-based stats.
Identities = 54/187 (29%), Positives = 87/187 (47%), Gaps = 3/187 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ I+ P G++ L + L + + + +V HTTR+ R EV G +YHFVSR
Sbjct 1 MTHSTGTLYIISAPSGAGKSSLVKALTDAKPE-IRVSVSHTTRAMRPGEVDGVNYHFVSR 59
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ F G F+E E NLYGTS ++Q +++G +L + Q + +R +
Sbjct 60 ETFVKMGEHGDFLERAEVFGNLYGTSQSHLQQTLDAGHDLILEIDWQGAEQVRKLMPQAR 119
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI PPS + L L G++ + E EM ++ +D I+N D A
Sbjct 120 SIFILPPSLQALHQRLTNRGQDSDEVIDGRMREAVSEM--SHYVDYDYLIINDDFAHALG 177
Query 654 ELLRLIN 660
+L +
Sbjct 178 DLKAIFR 184
>sp|Q9Z0U1|ZO2_MOUSE Tight junction protein ZO-2 OS=Mus musculus
OX=10090 GN=Tjp2 PE=1 SV=2
Length=1167
Score = 266 bits (680), Expect = 2e-75, Method: Composition-based stats.
Identities = 94/460 (20%), Positives = 184/460 (40%), Gaps = 77/460 (17%)
Query 226 KVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVK 285
+ A + DE +Y G K+VR +K + L N++ + ++ I +
Sbjct 469 RTAPRVFLRPSPEDEAIY-------GPNTKMVRFKKGDSVGLRLAGGNDV-GIFVAGIQE 520
Query 286 GGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK-----P 340
G +AE+ G L EGD++L++N + RG + L ++ T ++ +
Sbjct 521 GTSAEQEG-LQEGDQILKVNTQDFRGLVREDAVLYLLEIPKGETVTILAQSRADVYRDIL 579
Query 341 PPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ---EDPNWWQAYREGD 397
+ +++HF+ + L+F +G++ V+ W A R G+
Sbjct 580 ACGRGDSFFIRSHFECEKETP-------QSLAFTRGEVFRVVDTLYDGKLGHWLAVRIGN 632
Query 398 EDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEK-------SGKLWCAKKNKKKRKKVLY 450
E + GL+P KS +Q +++ E+ KKN +K ++ L
Sbjct 633 ELEK---GLIPNKSRAEQMASVQNAQRENAGDRADFWRMRGQRSSGGVKKNLRKSREDLA 689
Query 451 NANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASA 510
A + + YE++ L + A KRP++L GP + +RL + D F +A
Sbjct 690 AAVSV----STKFPAYEKVLL--REAGFKRPVVLFGPI---ADIAMERLATELPDLFQTA 740
Query 511 VPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSG 570
+ + + AG + K+ +++VRQ+I
Sbjct 741 -------KTEPKDAGSE-------------------------KSSGVVRLNTVRQIIEQD 768
Query 571 KICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTRE 630
K LL + +++ L + P +IF P S++ ++ + + + R++ ++ +
Sbjct 769 KHALLDVTPKAVDLLNYTQWFPIVIFFNPDSRQGVKT-IRQRLSPTSNKSSRKLFDQANK 827
Query 631 MEQNNGHYFDTAI-VNSDLDKAYQELLRLINKLDTEPQWV 669
+++ H F I VNS D + L I + E WV
Sbjct 828 LKKTCSHLFTATINVNSANDGWFGSLKDSIQQQQNEAVWV 867
Score = 52.4 bits (124), Expect = 1e-05, Method: Composition-based stats.
Identities = 22/99 (22%), Positives = 40/99 (40%), Gaps = 11/99 (11%)
Query 257 VRIEKARDIPLGATVR---------NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
V ++K G V N S++IS ++ GG A+ GLL E D V+ +NG
Sbjct 11 VTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPAD--GLLQENDRVVMVNGT 68
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKET 346
+ + L V+ ++++ P + +
Sbjct 69 PMEDVLHSFAVQQLRKSGKIAAIVVKRPRKVQVAPLQGS 107
Score = 47.0 bits (110), Expect = 6e-04, Method: Composition-based stats.
Identities = 19/88 (22%), Positives = 38/88 (43%), Gaps = 3/88 (3%)
Query 250 GGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+ ++ + + G + ++ + I + + G A K G LHEGD +L+ING
Sbjct 282 PDRPIGVLLTKSKANEEYGLRLGSQ---IFIKEMTRTGLATKDGNLHEGDIILKINGTVT 338
Query 310 RGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
+ + L+ G L V++ +
Sbjct 339 ENMSLTDARKLIEKSRGKLQLVVLRDSK 366
>sp|Q8DNR5|KGUA_STRR6 Guanylate kinase OS=Streptococcus pneumoniae
(strain ATCC BAA-255 / R6) OX=171101 GN=gmk PE=3 SV=1
Length=208
Score = 243 bits (621), Expect = 2e-75, Method: Composition-based stats.
Identities = 50/185 (27%), Positives = 87/185 (47%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A+R I+ GP G+ +R+ + +++F +V TTR++R EV G DY F +R+
Sbjct 2 ADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q ++ I
Sbjct 62 FEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKKKVPDAVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L+ L G + + I + + E +D AIVN + A + +
Sbjct 122 FLTPPDLDELQDRLVGRGTDSAEVIAQRIEKA--KEEIALMREYDYAIVNDQVSLAAERV 179
Query 656 LRLIN 660
+I
Sbjct 180 KCVIE 184
>sp|Q1LQ34|KGUA_CUPMC Guanylate kinase OS=Cupriavidus metallidurans
(strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34) OX=266264
GN=gmk PE=3 SV=1
Length=216
Score = 243 bits (621), Expect = 3e-75, Method: Composition-based stats.
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 3/194 (2%)
Query 467 EEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGR 526
E A +++ P G++ L L+ ++K ++ HTTRS R E GR
Sbjct 3 ETTHTAIDTAYPGNLFMVVAPSGAGKSTLVNALLAQDK-AIRLSISHTTRSPRPGEQNGR 61
Query 527 DYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLR 586
+YHF+S F A G+F+E E N Y TS + + + G LL + Q + +
Sbjct 62 EYHFISVDEFRAARDRGEFLEWAEVHGNYYATSRVWIEEQMAQGTDVLLEIDWQGAQQVH 121
Query 587 NSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNS 646
IFI PPS L L K G++ +R ++ EM ++ D I+N
Sbjct 122 KRFSNAVEIFILPPSLTALEERLKKRGQDEPNVIVRRLLAAGSEM--SHASESDYVIINE 179
Query 647 DLDKAYQELLRLIN 660
D A ++L +++
Sbjct 180 VFDDALKQLQNVVH 193
>sp|P99176|KGUA_STAAN Guanylate kinase OS=Staphylococcus aureus
(strain N315) OX=158879 GN=gmk PE=1 SV=1
Length=207
Score = 243 bits (620), Expect = 3e-75, Method: Composition-based stats.
Identities = 55/187 (29%), Positives = 89/187 (48%), Gaps = 2/187 (1%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ I+L GP G+ +R+R+ + ++ TTR R+ EV G DY F +R
Sbjct 1 MDNEKGLLIVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFFKTR 60
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
AFEA I +FIE+ E+ N YGT + V+ ++ G L + + K +R
Sbjct 61 DAFEALIKDDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDAL 120
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+APPS + LR L G + I E +E+E N +D +VN +++ A
Sbjct 121 FIFLAPPSLDHLRERLVGRGTESNEKIQSRINEARKEVEMMN--LYDYVVVNDEVELAKN 178
Query 654 ELLRLIN 660
+ ++
Sbjct 179 RIQCIVE 185
>sp|P65219|KGUA_STAAM Guanylate kinase OS=Staphylococcus aureus
(strain Mu50 / ATCC 700699) OX=158878 GN=gmk PE=3 SV=1
Length=207
Score = 243 bits (620), Expect = 3e-75, Method: Composition-based stats.
Identities = 55/187 (29%), Positives = 89/187 (48%), Gaps = 2/187 (1%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ I+L GP G+ +R+R+ + ++ TTR R+ EV G DY F +R
Sbjct 1 MDNEKGLLIVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFFKTR 60
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
AFEA I +FIE+ E+ N YGT + V+ ++ G L + + K +R
Sbjct 61 DAFEALIKDDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDAL 120
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+APPS + LR L G + I E +E+E N +D +VN +++ A
Sbjct 121 FIFLAPPSLDHLRERLVGRGTESNEKIQSRINEARKEVEMMN--LYDYVVVNDEVELAKN 178
Query 654 ELLRLIN 660
+ ++
Sbjct 179 RIQCIVE 185
>sp|Q9HTM2|KGUA_PSEAE Guanylate kinase OS=Pseudomonas aeruginosa
(strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 /
LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=gmk PE=1 SV=1
Length=203
Score = 243 bits (620), Expect = 3e-75, Method: Composition-based stats.
Identities = 59/191 (31%), Positives = 90/191 (47%), Gaps = 5/191 (3%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
I+ P G+ L + L++ + +V HTTR R EV G +YHF SR+ F A
Sbjct 3 GTLYIVSAPSGAGKTSLVKALLDAAPE-VRVSVSHTTRGMRPGEVDGVNYHFTSREEFLA 61
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+ +F+EH E NLYGTS V + + G +L + Q + +R + IFI
Sbjct 62 MLERNEFLEHAEVFGNLYGTSQRWVEKTLAEGLDLILEIDWQGAQQVRRLMPEAQSIFIL 121
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPSQE LR L G++ R + E EM ++ +D ++N D A +L +
Sbjct 122 PPSQEALRQRLTNRGQDSDEVIERRMREAVSEM--SHYVEYDHLVINDDFAHALDDLKAI 179
Query 659 I--NKLDTEPQ 667
+L + Q
Sbjct 180 FRARQLRQDAQ 190
>sp|Q8R9S6|KGUA_CALS4 Guanylate kinase OS=Caldanaerobacter subterraneus
subsp. tengcongensis (strain DSM 15242 / JCM 11007
/ NBRC 100824 / MB4) OX=273068 GN=gmk PE=3 SV=1
Length=206
Score = 243 bits (620), Expect = 3e-75, Method: Composition-based stats.
Identities = 49/182 (27%), Positives = 88/182 (48%), Gaps = 3/182 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ I++ GP G+ + + L+ KEKD ++ TTR R EV G++Y F S + F+
Sbjct 6 QGLLIVISGPSGAGKGTICKALIEKEKD-LKLSISATTRQPRAGEVDGKNYFFKSEEEFK 64
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I F+E + + YGT + V + + G +L + Q ++ + IFI
Sbjct 65 RMIEEDAFLEWAKVYDHYYGTPKEFVLKNLEEGNDVVLEIDIQGALKVKEKFPEGVFIFI 124
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS E LR + K G + E ++ E+ N ++ ++N D+D+A +++
Sbjct 125 LPPSMEELRNRIKKRGTESEEEIIKRFKSAYEEL--NYVSKYNYVVINDDVDRAVEKIRA 182
Query 658 LI 659
+I
Sbjct 183 II 184
>sp|P57509|KGUA_BUCAI Guanylate kinase OS=Buchnera aphidicola
subsp. Acyrthosiphon pisum (strain APS) OX=107806 GN=gmk PE=3
SV=1
Length=207
Score = 243 bits (620), Expect = 3e-75, Method: Composition-based stats.
Identities = 49/180 (27%), Positives = 88/180 (49%), Gaps = 3/180 (2%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
I+ P G++ L Q L+ + ++ HTTR R E+ G+ Y+F+S++ FE
Sbjct 6 LFIISAPSGTGKSSLIQGLLKSKTLYNTRVSISHTTRIIRPGELHGKHYYFISKKEFEIM 65
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
I F+E+ + N YGTS + +++ SG L + Q K ++ K IF+ P
Sbjct 66 IKQEYFLEYAKVFSNYYGTSRKYIEKMLFSGIDVFLDIDWQGAKQIKCKMPKSKSIFLLP 125
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
PS++ L L + G++ + + EM+ + +D I+N D +A +L+ +I
Sbjct 126 PSKDTLYKRLRERGQDSDSVIANRMEKAVDEMQ--HYSEYDYLIINDDFKQAVNDLITII 183
>sp|Q6GHM6|KGUA_STAAR Guanylate kinase OS=Staphylococcus aureus
(strain MRSA252) OX=282458 GN=gmk PE=3 SV=1
Length=207
Score = 243 bits (620), Expect = 4e-75, Method: Composition-based stats.
Identities = 55/187 (29%), Positives = 89/187 (48%), Gaps = 2/187 (1%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ I+L GP G+ +R+R+ + ++ TTR R+ EV G DY F +R
Sbjct 1 MDNEKGLLIVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFFKTR 60
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
AFEA I +FIE+ E+ N YGT + V+ ++ G L + + K +R
Sbjct 61 DAFEALIKDDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDAL 120
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+APPS + LR L G + I E +E+E N +D +VN +++ A
Sbjct 121 FIFLAPPSLDHLRERLVGRGTESDEKIQSRINEARKEVEMMN--LYDYVVVNDEVELAKN 178
Query 654 ELLRLIN 660
+ ++
Sbjct 179 RIQCIVE 185
>sp|Q2YXF9|KGUA_STAAB Guanylate kinase OS=Staphylococcus aureus
(strain bovine RF122 / ET3-1) OX=273036 GN=gmk PE=3 SV=1
Length=207
Score = 243 bits (620), Expect = 4e-75, Method: Composition-based stats.
Identities = 55/187 (29%), Positives = 89/187 (48%), Gaps = 2/187 (1%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ I+L GP G+ +R+R+ + ++ TTR R+ EV G DY F +R
Sbjct 1 MDNEKGLLIVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFFKTR 60
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
AFEA I +FIE+ E+ N YGT + V+ ++ G L + + K +R
Sbjct 61 DAFEALIKDDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDAL 120
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+APPS + LR L G + I E +E+E N +D +VN +++ A
Sbjct 121 FIFLAPPSLDHLRERLVGRGTESDEKIQSRINEARKEVEMMN--LYDYVVVNDEVELAKN 178
Query 654 ELLRLIN 660
+ ++
Sbjct 179 RIQCIVE 185
>sp|Q5L0S8|KGUA_GEOKA Guanylate kinase OS=Geobacillus kaustophilus
(strain HTA426) OX=235909 GN=gmk PE=3 SV=1
Length=205
Score = 243 bits (620), Expect = 4e-75, Method: Composition-based stats.
Identities = 51/186 (27%), Positives = 83/186 (45%), Gaps = 2/186 (1%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
R I++ GP G+ +R+ L ++ +V TTR R+ EV G DY F +R
Sbjct 1 MKNERGLLIVMSGPSGVGKGTVRKALFSQPDINLHYSVSVTTRKPREGEVEGVDYFFRTR 60
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ FE I K +E E+ N YGT ID V + + GK L + Q +R + +
Sbjct 61 EQFEQMIRENKLLEWAEYVGNYYGTPIDYVEKTLAEGKDVFLEIEVQGAMKVRRAFPEAL 120
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+APPS L + G K + E+E +D + N +++ A +
Sbjct 121 FIFLAPPSLTELEKRIMGRGTESKELIENRLRAAKEELEMM--DEYDYVVENDEVELACE 178
Query 654 ELLRLI 659
+ ++
Sbjct 179 RIKAIV 184
>sp|Q9JYB5|KGUA_NEIMB Guanylate kinase OS=Neisseria meningitidis
serogroup B (strain MC58) OX=122586 GN=gmk PE=3 SV=1
Length=205
Score = 243 bits (619), Expect = 5e-75, Method: Composition-based stats.
Identities = 56/184 (30%), Positives = 91/184 (49%), Gaps = 3/184 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ G+ L RL+ + +V HTTR R+ E G YHFVS++ F
Sbjct 5 RKGNIFIISAASGTGKTTLVSRLLANH-NGLRVSVSHTTRPPREGEANGVHYHFVSKEEF 63
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
E+ IA F+E+ + N YGT + V + +G +L + Q +R++ + IF
Sbjct 64 ESLIAQEAFLEYADVFGNYYGTGAEGVNALAAAGYDVILEIDVQGAAQVRDALPEAVGIF 123
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS + L A L G + + R + + E+EQ+ FD +VN DL +A ++L
Sbjct 124 ILPPSFDVLAARLNGRGTDSREVIQRRLSKARHEIEQSV--LFDFVVVNDDLARAEEDLR 181
Query 657 RLIN 660
++N
Sbjct 182 HIVN 185
>sp|Q97PA3|KGUA_STRPN Guanylate kinase OS=Streptococcus pneumoniae
serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=gmk
PE=3 SV=1
Length=208
Score = 243 bits (619), Expect = 5e-75, Method: Composition-based stats.
Identities = 50/185 (27%), Positives = 87/185 (47%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A+R I+ GP G+ +R+ + +++F +V TTR++R EV G DY F +R+
Sbjct 2 ADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q ++ I
Sbjct 62 FEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKKKVPDAVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L+ L G + + I + + E +D AIVN + A + +
Sbjct 122 FLTPPDLDELQDRLVGRGTDSAEVIAQRIEKA--KEEIALMREYDYAIVNDQVPLAAERV 179
Query 656 LRLIN 660
+I
Sbjct 180 KCVIE 184
>sp|Q2L090|KGUA_BORA1 Guanylate kinase OS=Bordetella avium (strain
197N) OX=360910 GN=gmk PE=3 SV=1
Length=210
Score = 243 bits (619), Expect = 5e-75, Method: Composition-based stats.
Identities = 49/190 (26%), Positives = 89/190 (47%), Gaps = 3/190 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
A+ +++ P G++ L + L++++ ++ TTR+ R E GRDYHFV++
Sbjct 1 MSAHSGNVFMVVAPSGAGKSSLVRALLDRDPS-IVLSISSTTRAPRPGEQDGRDYHFVTK 59
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+AF A A +E E N YGT + +G+ LL + Q + ++ +
Sbjct 60 EAFLAQREANNLLEWAEVHGNFYGTPRGRIDAATAAGQDVLLEIDWQGARQVKQRYPEAI 119
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI PPS E L+ L G++ + R ++ E+ + + I+N + A
Sbjct 120 GIFILPPSIEALQERLKARGQDSEQVISRRLLAAGGEI--AHAPECEYVIINQEFSLALS 177
Query 654 ELLRLINKLD 663
EL ++I+
Sbjct 178 ELTQIISAAR 187
>sp|Q31DP7|KGUA_HYDCU Guanylate kinase OS=Hydrogenovibrio crunogenus
(strain DSM 25203 / XCL-2) OX=317025 GN=gmk PE=3 SV=1
Length=205
Score = 242 bits (618), Expect = 6e-75, Method: Composition-based stats.
Identities = 50/181 (28%), Positives = 81/181 (45%), Gaps = 3/181 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
I+ P G+ L +L K+ R ++ TTR +R E G +Y F+S AF+
Sbjct 3 GSLYIISAPSGAGKTSLVSKLTEKD-SRIQVSISSTTRPKRPGEEDGVNYVFLSVDAFKQ 61
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+A F+EH + N YGTS V + K +L + Q + +R +FI
Sbjct 62 KVAENDFLEHAQVFDNYYGTSKSVVESKLAEDKDVILEIDWQGAQQVRKLIPDAVSVFIL 121
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS + L L G + + R + + EM+ + + FD ++N+ D A EL +
Sbjct 122 PPSLKELEKRLRGRGTDSEDVIERRMSDAVNEMK--HFNEFDYLVINNHFDTALSELHSI 179
Query 659 I 659
Sbjct 180 F 180
>sp|Q2QPW1|GMK1_ORYSJ Guanylate kinase 1 OS=Oryza sativa subsp.
japonica OX=39947 GN=GK1 PE=2 SV=2
Length=382
Score = 248 bits (634), Expect = 7e-75, Method: Composition-based stats.
Identities = 63/182 (35%), Positives = 103/182 (57%), Gaps = 1/182 (1%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
+PI++ GP G+ L +LM + +F +V HTTR+ R++E+ G YHF R E +
Sbjct 129 KPIVISGPSGVGKGTLIAKLMKEYPSKFGFSVSHTTRAPREKEIDGVHYHFTERSKIEEE 188
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
I+ GKF+E N+YGTS+++V V + GK C+L + Q +++R S L+ IF+ P
Sbjct 189 ISEGKFLEFAHVHGNVYGTSVEAVESVTDEGKRCILDIDVQGARSVRASSLEAIFIFVCP 248
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNG-HYFDTAIVNSDLDKAYQELLRL 658
PS E L L G + + + + E++Q+N FD +VN DL+ Y+ L +L
Sbjct 249 PSFEELEKRLRARGTETEEQIQKRLRNARAELDQSNSPGLFDHLLVNDDLEACYENLKKL 308
Query 659 IN 660
++
Sbjct 309 LS 310
>sp|Q4L5R1|KGUA_STAHJ Guanylate kinase OS=Staphylococcus haemolyticus
(strain JCSC1435) OX=279808 GN=gmk PE=3 SV=1
Length=207
Score = 242 bits (618), Expect = 8e-75, Method: Composition-based stats.
Identities = 51/187 (27%), Positives = 90/187 (48%), Gaps = 2/187 (1%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ I+L GP G+ +R+ + + + +V TTR+ R+ EV G DY F ++
Sbjct 1 MDNEKGLLIVLSGPSGVGKGTVRKEIFDDPTTSYKYSVSMTTRNMREGEVDGVDYFFKTK 60
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ FEA I +FIE+ E+ N YGT + V+ + +G L + + K +R
Sbjct 61 EEFEALIQEDQFIEYAEYVGNYYGTPVQYVKDTMAAGHDVFLEIEVEGAKQVRKKFPDAL 120
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+APPS + L+ L G + + E +E+E N +D +VN ++ A +
Sbjct 121 FIFLAPPSLDHLKERLVGRGTESDEKIQSRVNEARKEVEMMN--LYDYVVVNDEVHLAKE 178
Query 654 ELLRLIN 660
+ ++
Sbjct 179 RIQSIVE 185
>sp|Q2SY72|KGUA_BURTA Guanylate kinase OS=Burkholderia thailandensis
(strain ATCC 700388 / DSM 13276 / CCUG 48851 / CIP 106301
/ E264) OX=271848 GN=gmk PE=3 SV=1
Length=227
Score = 243 bits (619), Expect = 9e-75, Method: Composition-based stats.
Identities = 46/181 (25%), Positives = 83/181 (46%), Gaps = 3/181 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+++ P G++ L L++K+ + ++ +TTR R E G+ YHF + + F A
Sbjct 21 GNLFMVVAPSGAGKSTLVNALLSKDPE-ICLSISYTTRKPRSGEQDGQHYHFTTVEDFRA 79
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
A+ +F+E E N YGTS + + + SG LL + Q + ++ IFI
Sbjct 80 RHASHEFLESAEVHGNYYGTSRVWIEEQMKSGHDVLLEIDWQGAQQVKKQFRNAVGIFIL 139
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS L L K G++ R ++ E+ + + ++N + A EL +
Sbjct 140 PPSLAALEERLKKRGQDEPNVITRRLLAAGSEI--AHAAEAEYVVINETFEHALAELECI 197
Query 659 I 659
+
Sbjct 198 V 198
>sp|Q1BY73|KGUA_BURO1 Guanylate kinase OS=Burkholderia orbicola
(strain AU 1054) OX=331271 GN=gmk PE=3 SV=1
Length=227
Score = 243 bits (619), Expect = 1e-74, Method: Composition-based stats.
Identities = 47/181 (26%), Positives = 85/181 (47%), Gaps = 3/181 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+++ P G++ L L++K+ D ++ +TTR R E G+ YHF + + F A
Sbjct 21 GNLFMVVAPSGAGKSTLVNALLSKDSD-ICLSISYTTRKPRPGEQDGQHYHFTTVEDFRA 79
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
AA +F+E E N YGTS + + + +G LL + Q ++ IFI
Sbjct 80 RHAAHEFLESAEVHGNYYGTSRVWIEEQMRNGHDVLLEIDWQGALQVKKQFRNAVGIFIL 139
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS + L L K G++ R ++ E+ + + ++N + ++A EL +
Sbjct 140 PPSLDALEERLKKRGQDEPNVITRRLLAAGSEI--AHASEAEYVVINENFERALAELECI 197
Query 659 I 659
+
Sbjct 198 V 198
>sp|P60551|KGUA_GEOSL Guanylate kinase OS=Geobacter sulfurreducens
(strain ATCC 51573 / DSM 12127 / PCA) OX=243231 GN=gmk
PE=3 SV=1
Length=203
Score = 241 bits (616), Expect = 1e-74, Method: Composition-based stats.
Identities = 55/196 (28%), Positives = 85/196 (43%), Gaps = 5/196 (3%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
IL P G+ L + +++ + +V +TTR+ R E+ G+DY FVS F
Sbjct 5 GVLYILSAPSGAGKTTLCREIIDIFP-QLRHSVSYTTRTPRPGEIHGKDYFFVSMDEFHR 63
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
I A +F E E N YGTSI ++ + +G +L + Q + L+ IFI
Sbjct 64 MIDADEFAEWAEVHGNCYGTSIRTLEENRAAGVDLILDIDIQGARQLQERFAGGVYIFIL 123
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS E LR L + R I E+ + ++D IVN +A +EL +
Sbjct 124 PPSFEELRRRLNGRSSDSDEVISRRINAAAGEIRE--SRWYDYIIVNDQFSRAVEELKSV 181
Query 659 I--NKLDTEPQWVPST 672
I + T +
Sbjct 182 IIAEQCRTARVLDAVS 197
>sp|P0C0M9|KGUA_STAES Guanylate kinase OS=Staphylococcus epidermidis
(strain ATCC 12228 / FDA PCI 1200) OX=176280 GN=gmk PE=3
SV=1
Length=207
Score = 242 bits (617), Expect = 1e-74, Method: Composition-based stats.
Identities = 48/184 (26%), Positives = 88/184 (48%), Gaps = 2/184 (1%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+L GP G+ +R+++ + ++ TTR R+ E+ G DY F +++ F
Sbjct 4 EKGLLIVLSGPSGVGKGTVRKKIFEDPTTSYKYSISMTTRHMREGEIDGVDYFFKTKEEF 63
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
EA I +FIE+ ++ N YGT + V+ + G L + + K +R IF
Sbjct 64 EALIKDDQFIEYAQYVGNYYGTPVQYVKDTMEEGHDVFLEIEVEGAKQVRKKFPDALFIF 123
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+APPS + L+ L G + + E +E+E N +D +VN +++ A +
Sbjct 124 LAPPSLDDLKERLVGRGTESDEKIQSRVNEARKEVEMMN--LYDYVVVNDEVELAKNRIQ 181
Query 657 RLIN 660
++
Sbjct 182 SIVE 185
>sp|Q5HPY1|KGUA_STAEQ Guanylate kinase OS=Staphylococcus epidermidis
(strain ATCC 35984 / RP62A) OX=176279 GN=gmk PE=3 SV=1
Length=207
Score = 242 bits (617), Expect = 1e-74, Method: Composition-based stats.
Identities = 49/184 (27%), Positives = 88/184 (48%), Gaps = 2/184 (1%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+L GP G+ +R+++ + ++ TTR R+ E+ G DY F +++ F
Sbjct 4 EKGLLIVLSGPSGVGKGTVRKKIFEDPTTSYKYSISMTTRHMREGEIDGVDYFFKTKEEF 63
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
EA I +FIE+ ++ N YGT + V+ + G L + + K +R IF
Sbjct 64 EALIKDDQFIEYAQYVGNYYGTPVQYVKDTMEEGHDVFLEIEVEGAKQVRKKFPDALFIF 123
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+APPS + LR L G + + E +E+E N +D +VN +++ A +
Sbjct 124 LAPPSLDDLRERLVGRGTESDEKIQSRVNEARKEVEMMN--LYDYVVVNDEVELAKNRIQ 181
Query 657 RLIN 660
++
Sbjct 182 SIVE 185
>sp|Q1WUB5|KGUA_LIGS1 Guanylate kinase OS=Ligilactobacillus salivarius
(strain UCC118) OX=362948 GN=gmk PE=3 SV=1
Length=205
Score = 241 bits (616), Expect = 1e-74, Method: Composition-based stats.
Identities = 55/188 (29%), Positives = 99/188 (53%), Gaps = 2/188 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A R I+L GP G+ +R+ + ++ ++F +V TTR R EV G+DY+FVS++
Sbjct 2 AKRGMLIVLSGPSGVGKGTVRKEIFSQPGNKFHYSVSMTTREMRPGEVNGKDYYFVSKEE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE +IAAG+ +E+ ++ N YGT + V ++++SGK L + + +R I
Sbjct 62 FEQEIAAGQMLEYAQYVDNYYGTPLKYVNEMLDSGKDVFLEIEVKGAMQVREKAPDGLFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP LR + G + + + + E+E +D A+VN +++KA +++
Sbjct 122 FLTPPDLMELRQRIINRGTDDIDTINKRMKKAVDEIEMM--QNYDYAVVNDEVEKAAEKI 179
Query 656 LRLINKLD 663
+I
Sbjct 180 KTIIRAER 187
>sp|Q8DMQ7|KGUA_THEVB Guanylate kinase OS=Thermosynechococcus
vestitus (strain NIES-2133 / IAM M-273 / BP-1) OX=197221 GN=gmk
PE=3 SV=1
Length=191
Score = 241 bits (615), Expect = 1e-74, Method: Composition-based stats.
Identities = 63/185 (34%), Positives = 92/185 (50%), Gaps = 3/185 (2%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
+ I++ GP G+ L ++L + + A +V TTR R EVAG DY+FVS +
Sbjct 5 TPQPGQLIVITGPSGVGKGTLLRQLRQRHPE-LALSVSATTRPPRPTEVAGVDYYFVSVE 63
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
F+A IAAG+ +E EF + YGT + Q+I GK +L + Q + +R S +
Sbjct 64 EFKAMIAAGQLLEWAEFAGHYYGTPRQPLVQLIAQGKTVILEIELQGARQVRQSYPQARH 123
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFI PPS L L G++ + R + + E E FD IVN DL+K+
Sbjct 124 IFILPPSLAELEHRLRSRGQDSEEAIARRLAQA--ETEIAAAPEFDVQIVNDDLEKSLIA 181
Query 655 LLRLI 659
L I
Sbjct 182 LETAI 186
>sp|Q88WL7|KGUA_LACPL Guanylate kinase OS=Lactiplantibacillus
plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) OX=220668
GN=gmk PE=3 SV=1
Length=206
Score = 241 bits (616), Expect = 1e-74, Method: Composition-based stats.
Identities = 47/188 (25%), Positives = 91/188 (48%), Gaps = 2/188 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A + I+L GP G+ +R+ + + + + F +V TTR R EV G+DY+FVS++
Sbjct 2 AKQGMLIVLSGPSGVGKGTVRKEIFDSDDNDFQYSVSMTTRQMRPGEVDGKDYYFVSKEE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE +I +G +E+ ++ N YGT + ++Q + +GK L + +R I
Sbjct 62 FEDEIKSGGMLEYAKYVDNYYGTPLKYIKQSLAAGKDVFLEIEVNGAMQVREKMPDGVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP L+ + G + + + + E++ +D A++N ++ A + +
Sbjct 122 FLTPPDLMELKHRIIGRGTDDMSVINKRMAKAVDEIKMM--RNYDYAVINDEVPLAAERI 179
Query 656 LRLINKLD 663
+I
Sbjct 180 KAIIRSER 187
>sp|Q5NQE8|KGUA_ZYMMO Guanylate kinase OS=Zymomonas mobilis subsp.
mobilis (strain ATCC 31821 / ZM4 / CP4) OX=264203 GN=gmk
PE=3 SV=1
Length=216
Score = 241 bits (616), Expect = 2e-74, Method: Composition-based stats.
Identities = 44/185 (24%), Positives = 88/185 (48%), Gaps = 4/185 (2%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A R ++ P G++ + +R++ ++ D +V TTR +R EV G DYHFV
Sbjct 9 ARRGLLFVISSPSGAGKSTIARRILAED-DEIHLSVSVTTRPKRPGEVDGVDYHFVDVPT 67
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTL-RNSDLKPYI 594
F+ +A + +E N YGT V ++++ G+ L + Q + L + +
Sbjct 68 FKKMVAENQLLEWAHVFDNRYGTPRAPVEEMLHKGQDVLFDIDWQGAQQLWQQASGDTIR 127
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
++I PPS E L L G + + + + E+ ++ +D ++N D+D+ ++
Sbjct 128 VYILPPSFEELERRLRGRGTDSEEVIQKRMARAASEI--SHWDGYDYVLINDDMDECVKQ 185
Query 655 LLRLI 659
+ ++
Sbjct 186 VKNIL 190
>sp|Q3ALX6|KGUA_SYNSC Guanylate kinase OS=Synechococcus sp. (strain
CC9605) OX=110662 GN=gmk PE=3 SV=1
Length=185
Score = 240 bits (613), Expect = 2e-74, Method: Composition-based stats.
Identities = 54/181 (30%), Positives = 87/181 (48%), Gaps = 3/181 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+ ++ GP G+ L +L+ + + +V TTRS R E G +Y F SR FEA
Sbjct 5 GKLTLITGPSGVGKGTLVNQLLERHPQIW-LSVSATTRSPRQGEQDGINYFFHSRAGFEA 63
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+ G F+E EF N YGT V Q + +G+ LL + + + +R S + IF+A
Sbjct 64 LVEQGGFLEWAEFAGNCYGTPRGPVEQQMAAGRPVLLEIELEGARQVRRSFPDGFQIFLA 123
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS + L + G + + R + E+E FD ++N DL+ A ++ L
Sbjct 124 PPSFDELERRIRGRGTDSEDAIQRRLTRAREELEAQ--QEFDAVVINDDLESALNQVETL 181
Query 659 I 659
+
Sbjct 182 M 182
>sp|Q39IL2|KGUA_BURL3 Guanylate kinase OS=Burkholderia lata (strain
ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194
/ 383) OX=482957 GN=gmk PE=3 SV=1
Length=227
Score = 242 bits (617), Expect = 2e-74, Method: Composition-based stats.
Identities = 46/181 (25%), Positives = 84/181 (46%), Gaps = 3/181 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+++ P G++ L L++K+ D ++ +TTR R E G+ YHF + + F
Sbjct 21 GNLFMVVAPSGAGKSTLVNALLSKDSD-ICLSISYTTRKPRPGEQDGQHYHFTTVEDFRT 79
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
AA +F+E E N YGTS + + + +G LL + Q ++ IFI
Sbjct 80 RHAAHEFLESAEVHGNYYGTSRVWIEEQMKNGHDVLLEIDWQGALQVKKQFRNAVGIFIL 139
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS + L L K G++ R ++ E+ + + ++N + ++A EL +
Sbjct 140 PPSLDALEERLKKRGQDEPKVITRRLLAAGSEI--AHAPEAEYVVINENFERALAELECI 197
Query 659 I 659
+
Sbjct 198 V 198
>sp|Q95168|ZO2_CANLF Tight junction protein ZO-2 OS=Canis lupus
familiaris OX=9615 GN=TJP2 PE=1 SV=1
Length=1174
Score = 263 bits (672), Expect = 2e-74, Method: Composition-based stats.
Identities = 89/443 (20%), Positives = 178/443 (40%), Gaps = 68/443 (15%)
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
R G K+VR +K + L N++ + ++ I +G +AE+ G L EGD+
Sbjct 481 RPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGGNDV-GIFVAGIQEGTSAEQEG-LQEGDQ 538
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK-----PPPAKETVIHVKAHFD 355
+L++N + RG + L ++ ++ + + +++HF+
Sbjct 539 ILKVNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRADVYRDILACGRGDSFFIRSHFE 598
Query 356 YDPSDDPYVPCRELGLSFQKGDILHVISQ---EDPNWWQAYREGDEDNQPLAGLVPGKSF 412
+ L+F +G++ V+ W A R G+E + GL+P KS
Sbjct 599 CEKETP-------QSLAFSRGEVFRVVDTLYDGKLGHWLAVRIGNELEK---GLIPNKSR 648
Query 413 QQQREAMKQTIEEDKEPEK-----SGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYE 467
+Q +++ ++ G+ KKN +K ++ L A + + YE
Sbjct 649 AEQMASVQNAQRDNAGDRADFWRMRGQRSGMKKNLRKSREDLTAAVSV----STKFPAYE 704
Query 468 EMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRD 527
+ L + A KRP++L GP + ++L N+ D F +A + + + AG +
Sbjct 705 RVLL--REAGFKRPVVLFGPI---ADIALEKLANELPDLFQTA-------KTEPKDAGSE 752
Query 528 YHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN 587
K+ +++VRQ+I K LL + +++ L
Sbjct 753 -------------------------KSSGVVRLNTVRQIIEQDKHALLDVTPKAVDLLNY 787
Query 588 SDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAI-VNS 646
+ P +IF P S++ ++ + + + R++ ++ ++++ H F I +NS
Sbjct 788 TQWFPIVIFFNPDSRQGVKTM-RQRLNPTSNKSSRKLYDQANKLKKTCAHLFTATINLNS 846
Query 647 DLDKAYQELLRLINKLDTEPQWV 669
D + L I E WV
Sbjct 847 ANDSWFGSLKDTIQHQQGEAVWV 869
Score = 52.4 bits (124), Expect = 1e-05, Method: Composition-based stats.
Identities = 22/99 (22%), Positives = 40/99 (40%), Gaps = 11/99 (11%)
Query 257 VRIEKARDIPLGATVR---------NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
V ++K G V N S++IS ++ GG A+ GLL E D V+ +NG
Sbjct 11 VTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPAD--GLLQENDRVVMVNGT 68
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKET 346
+ + L V+ ++++ P + +
Sbjct 69 PMEDVLHSFAVQQLRKSGKIAAIVVKRPRKVQLAPPQGS 107
Score = 47.0 bits (110), Expect = 6e-04, Method: Composition-based stats.
Identities = 23/114 (20%), Positives = 43/114 (38%), Gaps = 7/114 (6%)
Query 224 HDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRI 283
H + +L D + G V +++ + + L + I ++
Sbjct 264 HLRSRSPSPELRGRPDHAGQPDSDRPIG--VLLMKSKANEEYGLRL-----GSQIFIKQM 316
Query 284 VKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
+ A K G LHEGD +L+ING + + L+ G L V++ +
Sbjct 317 TRTALATKDGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSK 370
>sp|Q3SLI4|KGUA_THIDA Guanylate kinase OS=Thiobacillus denitrificans
(strain ATCC 25259) OX=292415 GN=gmk PE=3 SV=1
Length=209
Score = 241 bits (615), Expect = 2e-74, Method: Composition-based stats.
Identities = 62/193 (32%), Positives = 94/193 (49%), Gaps = 3/193 (2%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
PA+ I+ P G+ L + L+ + +V HTTR+ R E GRDYHFV+R
Sbjct 4 PASPGVLYIVSAPSGAGKTSLVKALLKSDP-AIRLSVSHTTRAPRPGESDGRDYHFVARD 62
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
FE +A G+F+EH E N YGTS + Q +++G+ LL + Q + ++ +
Sbjct 63 TFEKMLADGEFLEHAEVYGNFYGTSRGRIGQELDAGRDLLLEIDWQGAEQVKRHFPQSTS 122
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFI PP+ LR L G++ R + + + FD IVN D D A Q+
Sbjct 123 IFILPPTFSALRTRLTGRGQDSPEIIERRLAAAAHD--VAHAEAFDYIIVNDDFDHALQD 180
Query 655 LLRLINKLDTEPQ 667
L+ + + E Q
Sbjct 181 LVAITRSIRLEAQ 193
>sp|Q4FQY7|KGUA_PSYA2 Guanylate kinase OS=Psychrobacter arcticus
(strain DSM 17307 / VKM B-2377 / 273-4) OX=259536 GN=gmk
PE=3 SV=1
Length=208
Score = 241 bits (614), Expect = 2e-74, Method: Composition-based stats.
Identities = 54/181 (30%), Positives = 81/181 (45%), Gaps = 3/181 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
I+ G+ L ++L+ D +V HTTR R E+ G YHF F
Sbjct 3 GSLFIITAASGTGKTSLVKQLLATTND-LTVSVSHTTRDPRPGEIDGHHYHFTDVDNFVT 61
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
I+ +F+EH E N YGTS SVR +++G +L + Q ++ +IFI
Sbjct 62 AISESQFLEHAEVFGNYYGTSEQSVRAQLDAGVDVILEIDWQGALQVKKIFTDAIMIFIL 121
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS LR L+ G++ + + EM Q FD I+N + + A EL +
Sbjct 122 PPSIATLRQRLSTRGQDSMEVIEQRLAGAVNEMAQYIN--FDYVIINDNFEVALTELKAI 179
Query 659 I 659
I
Sbjct 180 I 180
>sp|Q5M3I4|KGUA_STRT2 Guanylate kinase OS=Streptococcus thermophilus
(strain ATCC BAA-250 / LMG 18311) OX=264199 GN=gmk PE=3
SV=1
Length=209
Score = 241 bits (614), Expect = 3e-74, Method: Composition-based stats.
Identities = 55/185 (30%), Positives = 89/185 (48%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + +K +F +V TTR++R EV G+DY F SR+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSKSDHKFEYSVSMTTRAQRPGEVDGKDYFFRSREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q ++ I
Sbjct 62 FEELIRNGQMLEYAEYVGNYYGTPLAYVNETLDKGIDVFLEIEVQGALQVKKKVPDAVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP L L G + + + I E+ RE E +D IVN ++ A + +
Sbjct 122 FLTPPDLNELEERLVGRGTDSEEVIAQRI-ERARE-EIALMSEYDYTIVNDEVPLAAERV 179
Query 656 LRLIN 660
R+I
Sbjct 180 KRVIE 184
>sp|Q5LYX1|KGUA_STRT1 Guanylate kinase OS=Streptococcus thermophilus
(strain CNRZ 1066) OX=299768 GN=gmk PE=3 SV=1
Length=209
Score = 241 bits (614), Expect = 3e-74, Method: Composition-based stats.
Identities = 55/185 (30%), Positives = 89/185 (48%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + +K +F +V TTR++R EV G+DY F SR+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSKSDHKFEYSVSMTTRAQRPGEVDGKDYFFRSREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q ++ I
Sbjct 62 FEELIRNGQMLEYAEYVGNYYGTPLAYVNETLDKGIDVFLEIEVQGALQVKKKVPDAVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP L L G + + + I E+ RE E +D IVN ++ A + +
Sbjct 122 FLTPPDLNELEERLVGRGTDSEEVIAQRI-ERARE-EIALMSEYDYTIVNDEVPLAAERV 179
Query 656 LRLIN 660
R+I
Sbjct 180 KRVIE 184
>sp|Q6DB60|KGUA_PECAS Guanylate kinase OS=Pectobacterium atrosepticum
(strain SCRI 1043 / ATCC BAA-672) OX=218491 GN=gmk PE=3
SV=1
Length=207
Score = 240 bits (613), Expect = 3e-74, Method: Composition-based stats.
Identities = 55/187 (29%), Positives = 85/187 (45%), Gaps = 3/187 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G++ L Q L+ + ++ HTTR++R E G Y FV F
Sbjct 3 QGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSISHTTRAKRPGENHGEHYFFVEADEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I +F+EH E N YGTS ++ QV+ +G L + Q + +R + IF
Sbjct 63 KRMIQDSEFLEHAEVFGNYYGTSRPAIEQVLATGVDVFLDIDWQGAQQIRAKMPQARSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS+E L L G++ R + + EM + +D IVN D D A +L
Sbjct 123 ILPPSKEELARRLRGRGQDSDEVIARRMSQAVAEM--THYGEYDYLIVNDDFDLALLDLK 180
Query 657 RLINKLD 663
+I
Sbjct 181 TIIRAER 187
>sp|Q72DM9|KGUA_DESVH Guanylate kinase OS=Desulfovibrio vulgaris
(strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 /
Hildenborough) OX=882 GN=gmk PE=3 SV=1
Length=207
Score = 240 bits (613), Expect = 4e-74, Method: Composition-based stats.
Identities = 60/177 (34%), Positives = 92/177 (52%), Gaps = 3/177 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++L P G+ L +RL+ + RFA +V +TTR R+ EV G+DYHFV+ +AF
Sbjct 10 LVLCAPSGTGKTTLTRRLLTEFP-RFAFSVSYTTRKPRNGEVDGKDYHFVTVEAFLRLRD 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
AG F E E N YGT + + +++ G+ L + Q + LR S + +FI PPS
Sbjct 69 AGFFAEWAEVHGNFYGTPLKATLDLLDEGRDVLFDIDVQGARQLRASLQRGRYVFIMPPS 128
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
++ L L G + + R + +E+ + FD IVN DL++AY EL
Sbjct 129 RDELEHRLRARGTDDEETIARRLANAAKELRE--ARRFDAWIVNDDLERAYDELRAA 183
>sp|Q1GXB9|KGUA_METFK Guanylate kinase OS=Methylobacillus flagellatus
(strain KT / ATCC 51484 / DSM 6875) OX=265072 GN=gmk
PE=3 SV=1
Length=202
Score = 240 bits (612), Expect = 4e-74, Method: Composition-based stats.
Identities = 51/195 (26%), Positives = 81/195 (42%), Gaps = 5/195 (3%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ I+ P G+ L + L++ + + +V HTTR R E G YHFV F
Sbjct 2 KGNLFIITAPSGAGKTSLVRALLDGD-EHIKLSVSHTTRKPRPGEEDGVHYHFVEEARFV 60
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
+ G F+E + YGTS +V + G +L + Q + +R+ IFI
Sbjct 61 ELLNHGDFLESAQVHGAYYGTSQSTVNSALAEGYDLILEIDWQGAQQVRSLYADAISIFI 120
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS E L L ++ R + EM + FD +N + A ++L
Sbjct 121 LPPSMEALEQRLNNRAQDSAEVIARRLAAAREEMR--HVTEFDYVTINDRFEHALEDLRA 178
Query 658 LI--NKLDTEPQWVP 670
+I +L E Q +
Sbjct 179 IIRSQRLRREKQLIR 193
>sp|Q3A523|KGUA_SYNC1 Guanylate kinase OS=Syntrophotalea carbinolica
(strain DSM 2380 / NBRC 103641 / GraBd1) OX=338963 GN=gmk
PE=3 SV=1
Length=210
Score = 240 bits (612), Expect = 5e-74, Method: Composition-based stats.
Identities = 51/179 (28%), Positives = 84/179 (47%), Gaps = 3/179 (2%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
++ P G+ L +++++ D ++ TTR RR+ E G DYHFV+ + F+ +
Sbjct 7 LFVISAPSGAGKTSLCRQIVDIFPD-MRHSISFTTRPRRNGETDGVDYHFVTPEVFDTMV 65
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
A G F E N YGT++ ++++ G+ LL + Q L+ + IFI PP
Sbjct 66 AEGAFAEWARVHGNCYGTALATLQEAREQGQDLLLDIDCQGAAQLKRNCPDDVFIFILPP 125
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
S E L L + R + RE+ + +D IVN DL +A +E +I
Sbjct 126 SFEELERRLRGRNTDTAEVIARRLDNARREIRELVW--YDYLIVNEDLPRAVEEFKSII 182
>sp|Q38XU0|KGUA_LATSS Guanylate kinase OS=Latilactobacillus sakei
subsp. sakei (strain 23K) OX=314315 GN=gmk PE=3 SV=1
Length=203
Score = 239 bits (611), Expect = 6e-74, Method: Composition-based stats.
Identities = 56/186 (30%), Positives = 91/186 (49%), Gaps = 2/186 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+NR I+L GP G+ +RQ ++ E F +V TTR R E G DY+FVS++
Sbjct 2 SNRGMLIVLSGPSGVGKGTVRQAMLEDEFRDFHYSVSMTTRKPRPGEQDGVDYYFVSKEE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE +IA +E+ ++ N YGT + V Q + SG+ LL + Q +R I
Sbjct 62 FEQEIANDGMLEYAQYVDNYYGTPMKYVNQTLESGRDVLLEIEVQGAMQVREKCPDGVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP LR + K G + + + + + E+ +D A+VN ++ A Q +
Sbjct 122 FLTPPDLLELRNRIQKRGTDDQATIDKRMQKAADEIRMM--ENYDYAVVNDEIPNAVQRI 179
Query 656 LRLINK 661
++I
Sbjct 180 EKIIES 185
>sp|P65221|KGUA_STRA5 Guanylate kinase OS=Streptococcus agalactiae
serotype V (strain ATCC BAA-611 / 2603 V/R) OX=208435 GN=gmk
PE=3 SV=1
Length=209
Score = 239 bits (611), Expect = 7e-74, Method: Composition-based stats.
Identities = 54/185 (29%), Positives = 88/185 (48%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFDYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FEA I G+ +E+ E+ N YGT + V + ++ G L + Q +++ I
Sbjct 62 FEALIKEGQMLEYAEYVGNYYGTPLSYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP E L L G + + I E+ +E E +D A+VN + A + +
Sbjct 122 FLTPPDLEELEERLVGRGTDSPEVIAQRI-ERAKE-EIALMREYDYAVVNDQVSLAAERV 179
Query 656 LRLIN 660
R+I
Sbjct 180 KRVIE 184
>sp|P65220|KGUA_STRA3 Guanylate kinase OS=Streptococcus agalactiae
serotype III (strain NEM316) OX=211110 GN=gmk PE=3 SV=1
Length=209
Score = 239 bits (611), Expect = 7e-74, Method: Composition-based stats.
Identities = 54/185 (29%), Positives = 88/185 (48%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFDYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FEA I G+ +E+ E+ N YGT + V + ++ G L + Q +++ I
Sbjct 62 FEALIKEGQMLEYAEYVGNYYGTPLSYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP E L L G + + I E+ +E E +D A+VN + A + +
Sbjct 122 FLTPPDLEELEERLVGRGTDSPEVIAQRI-ERAKE-EIALMREYDYAVVNDQVSLAAERV 179
Query 656 LRLIN 660
R+I
Sbjct 180 KRVIE 184
>sp|Q3K368|KGUA_STRA1 Guanylate kinase OS=Streptococcus agalactiae
serotype Ia (strain ATCC 27591 / A909 / CDC SS700) OX=205921
GN=gmk PE=3 SV=1
Length=209
Score = 239 bits (611), Expect = 7e-74, Method: Composition-based stats.
Identities = 54/185 (29%), Positives = 88/185 (48%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFDYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FEA I G+ +E+ E+ N YGT + V + ++ G L + Q +++ I
Sbjct 62 FEALIKEGQMLEYAEYVGNYYGTPLSYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP E L L G + + I E+ +E E +D A+VN + A + +
Sbjct 122 FLTPPDLEELEERLVGRGTDSPEVIAQRI-ERAKE-EIALMREYDYAVVNDQVSLAAERV 179
Query 656 LRLIN 660
R+I
Sbjct 180 KRVIE 184
>sp|Q7VXZ3|KGUA_BORPE Guanylate kinase OS=Bordetella pertussis
(strain Tohama I / ATCC BAA-589 / NCTC 13251) OX=257313 GN=gmk
PE=3 SV=2
Length=215
Score = 239 bits (611), Expect = 9e-74, Method: Composition-based stats.
Identities = 46/195 (24%), Positives = 87/195 (45%), Gaps = 3/195 (2%)
Query 469 MSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDY 528
MS A +++ P G++ L + L++++ ++ TTR+ R E GR+Y
Sbjct 1 MSFLSMSAPSGNVFMVVAPSGAGKSSLVRALLDRDPS-LVLSISCTTRAPRPGEQDGREY 59
Query 529 HFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS 588
FV + F A + +E E N YGT D + + +G LL + Q + ++
Sbjct 60 RFVDQAEFARLRDAQQLLEWAEVHGNFYGTPRDRIDEATRAGHDVLLEIDWQGARQVKQR 119
Query 589 DLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDL 648
+ IF+ PPS + L + L G++ R ++ E+ + + I+N +
Sbjct 120 YPEAIGIFVLPPSIDELESRLKARGQDAPQVIARRLLAAGGEI--AHAPECEYVIINQEF 177
Query 649 DKAYQELLRLINKLD 663
A EL+++I+
Sbjct 178 SVALTELVQIISAAR 192
>sp|Q7W6B2|KGUA_BORPA Guanylate kinase OS=Bordetella parapertussis
(strain 12822 / ATCC BAA-587 / NCTC 13253) OX=257311 GN=gmk
PE=3 SV=1
Length=215
Score = 239 bits (611), Expect = 9e-74, Method: Composition-based stats.
Identities = 46/195 (24%), Positives = 87/195 (45%), Gaps = 3/195 (2%)
Query 469 MSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDY 528
MS A +++ P G++ L + L++++ ++ TTR+ R E GR+Y
Sbjct 1 MSFLSMSAPSGNVFMVVAPSGAGKSSLVRALLDRDPS-LVLSISCTTRAPRPGEQDGREY 59
Query 529 HFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS 588
FV + F A + +E E N YGT D + + +G LL + Q + ++
Sbjct 60 RFVDQAEFARLRDAQQLLEWAEVHGNFYGTPRDRIDEATRAGHDVLLEIDWQGARQVKQR 119
Query 589 DLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDL 648
+ IF+ PPS + L + L G++ R ++ E+ + + I+N +
Sbjct 120 YPEAIGIFVLPPSIDELESRLKARGQDAPQVIARRLLAAGGEI--AHAPECEYVIINQEF 177
Query 649 DKAYQELLRLINKLD 663
A EL+++I+
Sbjct 178 SVALTELVQIISAAR 192
>sp|Q7WI80|KGUA_BORBR Guanylate kinase OS=Bordetella bronchiseptica
(strain ATCC BAA-588 / NCTC 13252 / RB50) OX=257310 GN=gmk
PE=3 SV=1
Length=215
Score = 239 bits (611), Expect = 9e-74, Method: Composition-based stats.
Identities = 46/195 (24%), Positives = 87/195 (45%), Gaps = 3/195 (2%)
Query 469 MSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDY 528
MS A +++ P G++ L + L++++ ++ TTR+ R E GR+Y
Sbjct 1 MSFLSMSAPSGNVFMVVAPSGAGKSSLVRALLDRDPS-LVLSISCTTRAPRPGEQDGREY 59
Query 529 HFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS 588
FV + F A + +E E N YGT D + + +G LL + Q + ++
Sbjct 60 RFVDQAEFARLRDAQQLLEWAEVHGNFYGTPRDRIDEATRAGHDVLLEIDWQGARQVKQR 119
Query 589 DLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDL 648
+ IF+ PPS + L + L G++ R ++ E+ + + I+N +
Sbjct 120 YPEAIGIFVLPPSIDELESRLKARGQDAPQVIARRLLAAGGEI--AHAPECEYVIINQEF 177
Query 649 DKAYQELLRLINKLD 663
A EL+++I+
Sbjct 178 SVALTELVQIISAAR 192
>sp|Q99YM5|KGUA_STRP1 Guanylate kinase OS=Streptococcus pyogenes
serotype M1 OX=301447 GN=gmk PE=3 SV=1
Length=211
Score = 239 bits (611), Expect = 1e-73, Method: Composition-based stats.
Identities = 51/185 (28%), Positives = 89/185 (48%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + + I E+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQEVIAQRI-ERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLIN 660
R+I
Sbjct 180 KRIIE 184
>sp|Q3JBT3|KGUA_NITOC Guanylate kinase OS=Nitrosococcus oceani
(strain ATCC 19707 / BCRC 17464 / JCM 30415 / NCIMB 11848 /
C-107) OX=323261 GN=gmk PE=3 SV=1
Length=203
Score = 239 bits (610), Expect = 1e-73, Method: Composition-based stats.
Identities = 51/185 (28%), Positives = 85/185 (46%), Gaps = 3/185 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
I+ P G+ L + L D ++ HTTR R E G DYHFV+ FE
Sbjct 3 GSLFIVAAPSGAGKTSLVKALAASMAD-IRLSISHTTRPPRPGEQDGMDYHFVTEAIFET 61
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
G F+EH + + YGT+ +SV ++ G +L + Q + ++ IFI
Sbjct 62 MEGGGGFLEHAQVFGHRYGTAKESVLPLLAQGMDVILEIDWQGRRQVQAQFPHCVSIFIL 121
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS+E L L G++ + R + + E+ ++ + FD +VN D + A+ +L +
Sbjct 122 PPSRETLEHRLRLRGQDTEAVVARRMGDACAEI--SHYNEFDYLVVNDDFEVAHTDLRAI 179
Query 659 INKLD 663
+
Sbjct 180 VQSRR 184
>sp|Q21EC9|KGUA_SACD2 Guanylate kinase OS=Saccharophagus degradans
(strain 2-40 / ATCC 43961 / DSM 17024) OX=203122 GN=gmk
PE=3 SV=2
Length=205
Score = 239 bits (610), Expect = 1e-73, Method: Composition-based stats.
Identities = 54/191 (28%), Positives = 82/191 (43%), Gaps = 5/191 (3%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+ P G+ L L++ + +V HTTR++R E G +YHFVS + F
Sbjct 5 GTLYTVSAPSGAGKTSLVSALIDTTSNIM-VSVSHTTRAKRPGEQEGVNYHFVSHEQFAT 63
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+ F+EH + N YGTS V + G +L + Q + +R +FI
Sbjct 64 MVENNAFLEHAQVFTNFYGTSKQWVEDTLAKGIDVILEIDWQGAQQVRKLIPAAKSVFIL 123
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS+E LR L G++ + + E E+ IVN D D A E +
Sbjct 124 PPSRECLRERLTGRGQDDESVIDARMAEAKSEISHYVEAQ--YLIVNDDFDTALTEFRSI 181
Query 659 I--NKLDTEPQ 667
+ N+L E Q
Sbjct 182 VVANRLALEKQ 192
>sp|P0DB95|KGUA_STRPQ Guanylate kinase OS=Streptococcus pyogenes
serotype M3 (strain SSI-1) OX=193567 GN=gmk PE=3 SV=1
Length=211
Score = 239 bits (610), Expect = 1e-73, Method: Composition-based stats.
Identities = 51/185 (28%), Positives = 89/185 (48%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + + I E+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQEVIAQRI-ERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLIN 660
R+I
Sbjct 180 KRIIE 184
>sp|Q48S18|KGUA_STRPM Guanylate kinase OS=Streptococcus pyogenes
serotype M28 (strain MGAS6180) OX=319701 GN=gmk PE=3 SV=1
Length=211
Score = 239 bits (610), Expect = 1e-73, Method: Composition-based stats.
Identities = 51/185 (28%), Positives = 89/185 (48%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + + I E+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQEVIAQRI-ERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLIN 660
R+I
Sbjct 180 KRIIE 184
>sp|Q1J5I6|KGUA_STRPF Guanylate kinase OS=Streptococcus pyogenes
serotype M4 (strain MGAS10750) OX=370554 GN=gmk PE=3 SV=1
Length=211
Score = 239 bits (610), Expect = 1e-73, Method: Composition-based stats.
Identities = 51/185 (28%), Positives = 89/185 (48%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + + I E+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQEVIAQRI-ERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLIN 660
R+I
Sbjct 180 KRIIE 184
>sp|Q1JFN7|KGUA_STRPD Guanylate kinase OS=Streptococcus pyogenes
serotype M2 (strain MGAS10270) OX=370552 GN=gmk PE=3 SV=1
Length=211
Score = 239 bits (610), Expect = 1e-73, Method: Composition-based stats.
Identities = 51/185 (28%), Positives = 89/185 (48%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + + I E+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQEVIAQRI-ERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLIN 660
R+I
Sbjct 180 KRIIE 184
>sp|Q1JKP6|KGUA_STRPC Guanylate kinase OS=Streptococcus pyogenes
serotype M12 (strain MGAS9429) OX=370551 GN=gmk PE=3 SV=1
Length=211
Score = 239 bits (610), Expect = 1e-73, Method: Composition-based stats.
Identities = 51/185 (28%), Positives = 89/185 (48%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + + I E+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQEVIAQRI-ERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLIN 660
R+I
Sbjct 180 KRIIE 184
>sp|Q1JAJ4|KGUA_STRPB Guanylate kinase OS=Streptococcus pyogenes
serotype M12 (strain MGAS2096) OX=370553 GN=gmk PE=3 SV=1
Length=211
Score = 239 bits (610), Expect = 1e-73, Method: Composition-based stats.
Identities = 51/185 (28%), Positives = 89/185 (48%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + + I E+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQEVIAQRI-ERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLIN 660
R+I
Sbjct 180 KRIIE 184
>sp|P65223|KGUA_STRP8 Guanylate kinase OS=Streptococcus pyogenes
serotype M18 (strain MGAS8232) OX=186103 GN=gmk PE=3 SV=1
Length=211
Score = 239 bits (610), Expect = 1e-73, Method: Composition-based stats.
Identities = 51/185 (28%), Positives = 89/185 (48%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + + I E+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQEVIAQRI-ERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLIN 660
R+I
Sbjct 180 KRIIE 184
>sp|Q5XAP1|KGUA_STRP6 Guanylate kinase OS=Streptococcus pyogenes
serotype M6 (strain ATCC BAA-946 / MGAS10394) OX=286636 GN=gmk
PE=3 SV=1
Length=211
Score = 239 bits (610), Expect = 1e-73, Method: Composition-based stats.
Identities = 51/185 (28%), Positives = 89/185 (48%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + + I E+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQEVIAQRI-ERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLIN 660
R+I
Sbjct 180 KRIIE 184
>sp|P0DB94|KGUA_STRP3 Guanylate kinase OS=Streptococcus pyogenes
serotype M3 (strain ATCC BAA-595 / MGAS315) OX=198466 GN=gmk
PE=3 SV=1
Length=211
Score = 239 bits (610), Expect = 1e-73, Method: Composition-based stats.
Identities = 51/185 (28%), Positives = 89/185 (48%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R EV G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q +++ +
Sbjct 62 FEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP + L L G + + + I E+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLDELEDRLVGRGTDSQEVIAQRI-ERAKE-EIALMREYDYAVVNDEVALAAERV 179
Query 656 LRLIN 660
R+I
Sbjct 180 KRIIE 184
>sp|Q0SS73|KGUA_CLOPS Guanylate kinase OS=Clostridium perfringens
(strain SM101 / Type A) OX=289380 GN=gmk PE=3 SV=1
Length=216
Score = 239 bits (610), Expect = 1e-73, Method: Composition-based stats.
Identities = 54/183 (30%), Positives = 93/183 (51%), Gaps = 3/183 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
NR I++ GP G+ + + L+ K D F +V TTR+ R EV G +YHF++++ F
Sbjct 9 NRGVLIVISGPSGAGKGTICKALLEKHDDIF-ISVSATTRNPRVGEVDGVNYHFLTKEEF 67
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ IA F+EH E N YGT SV ++++ GK +L + Q ++ IF
Sbjct 68 KQRIAEDDFLEHAEVYGNYYGTPKSSVEKMLDEGKNVILEIDIQGALKVKEKATDGVFIF 127
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS E L+ + K G + +E+ N ++ A+VN +++ A +++
Sbjct 128 ILPPSMEELKQRIIKRGSETPESLMTRFKSAYKEI--NYVSKYNYAVVNDNVEDAVKKIE 185
Query 657 RLI 659
++
Sbjct 186 AIL 188
>sp|Q5SI18|KGUA_THET8 Guanylate kinase OS=Thermus thermophilus
(strain ATCC 27634 / DSM 579 / HB8) OX=300852 GN=gmk PE=3 SV=1
Length=223
Score = 239 bits (611), Expect = 1e-73, Method: Composition-based stats.
Identities = 53/192 (28%), Positives = 92/192 (48%), Gaps = 4/192 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
R R ++ G G+ +R +++ + R ++ TTR R EV G DY+FV R
Sbjct 1 MKGMRGRLFVMTGASGVGKGTVRAKVLER--TRLFYSISMTTRPPRPGEVDGVDYYFVDR 58
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
FEA + F+E+ E+ +LYGT V + ++ G+ LL + Q ++ + +
Sbjct 59 PTFEALVREDGFLEYAEYVGHLYGTPRAPVERALSRGEDVLLEIEVQGALQVKRAVPEAV 118
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
+IF+ PPS L+ L GK+ + + + + E E N H FD +VN L++A
Sbjct 119 LIFLLPPSLSELKRRLVYRGKDSPEKIQKRLEQA--EWEIRNAHLFDYVVVNDVLEEAVA 176
Query 654 ELLRLINKLDTE 665
+ L ++
Sbjct 177 DFLAILTAERRR 188
>sp|Q0AXK8|KGUA_SYNWW Guanylate kinase OS=Syntrophomonas wolfei
subsp. wolfei (strain DSM 2245B / Goettingen) OX=335541 GN=gmk
PE=3 SV=1
Length=195
Score = 238 bits (608), Expect = 1e-73, Method: Composition-based stats.
Identities = 50/183 (27%), Positives = 83/183 (45%), Gaps = 3/183 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ ++ GP G+ L++ L+++ KD ++ TTR R EV G+ Y FV + F
Sbjct 3 RKGILFVISGPSGVGKGTLKKALLDQTKD-LNLSISATTRPARLGEVHGQHYFFVDQAKF 61
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
I F+E + NLYGT V + G+ LL + Q ++ IF
Sbjct 62 REMIEQDAFLEWAQVYSNLYGTPRGFVLNHLQQGRDVLLEIDIQGALQVKEKMPSGVFIF 121
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PP+ E L L G++ + + E E + Y+D +VN +D+A Q++
Sbjct 122 IYPPNLEELAFRLVSRGQDSQDSIEARL--AACENELKHIDYYDYLVVNDKIDRALQKIT 179
Query 657 RLI 659
+I
Sbjct 180 AII 182
>sp|Q8ER28|KGUA_OCEIH Guanylate kinase OS=Oceanobacillus iheyensis
(strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954
/ HTE831) OX=221109 GN=gmk PE=3 SV=1
Length=206
Score = 238 bits (608), Expect = 2e-73, Method: Composition-based stats.
Identities = 48/185 (26%), Positives = 89/185 (48%), Gaps = 3/185 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ IL GP G+ +R++L +E D ++ TTR RR EV G DY + +++ F
Sbjct 4 EKGILFILSGPSGVGKGTVRKKLFEEETD-LQYSISMTTRDRRPGEVDGVDYFYKTKEEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
E I G+ +E+ ++ N YGT + V + + +G+ L + Q ++ + + IF
Sbjct 63 EQLIKDGQLLEYAQYVNNYYGTPRNYVEETLENGQDVFLEIEVQGALQVKENFPEGVFIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+ PPS + L+ + G + L + E E+E + +D +VN + A ++
Sbjct 123 LFPPSLDELKNRIVSRGTESQELVLNRLKEARNEIEMMDA--YDYVVVNDKVQHAVDKVK 180
Query 657 RLINK 661
+I
Sbjct 181 TIIKS 185
>sp|Q46YE8|KGUA_CUPPJ Guanylate kinase OS=Cupriavidus pinatubonensis
(strain JMP 134 / LMG 1197) OX=264198 GN=gmk PE=3 SV=1
Length=216
Score = 239 bits (609), Expect = 2e-73, Method: Composition-based stats.
Identities = 49/182 (27%), Positives = 82/182 (45%), Gaps = 3/182 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+++ P G++ L L+ ++ ++ HTTR+ R E GR+YHF + +F A
Sbjct 15 GNLFMVVAPSGAGKSTLVNALLAQD-AAIRLSISHTTRAPRPGEQDGREYHFCTVDSFRA 73
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
G+F+E E N Y TS + + + G LL + Q + + IFI
Sbjct 74 ARDRGEFLEWAEVHGNYYATSRVWIEEQMAQGNDVLLEIDWQGAQQVHQRFSNAVEIFIL 133
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS L L K G++ +R ++ EM ++ D I+N D A +EL +
Sbjct 134 PPSLTALEDRLKKRGQDEPNVIVRRLLAAGSEM--SHASESDYVIINEVFDNALEELRNV 191
Query 659 IN 660
+
Sbjct 192 VR 193
>sp|Q1Q973|KGUA_PSYCK Guanylate kinase OS=Psychrobacter cryohalolentis
(strain ATCC BAA-1226 / DSM 17306 / VKM B-2378 / K5)
OX=335284 GN=gmk PE=3 SV=1
Length=208
Score = 238 bits (608), Expect = 2e-73, Method: Composition-based stats.
Identities = 54/181 (30%), Positives = 80/181 (44%), Gaps = 3/181 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
I+ G+ L ++L+ D +V HTTR R E+ G YHF F
Sbjct 3 GSLFIITAASGTGKTSLVKQLLATTND-LTVSVSHTTREPRPGEIDGHHYHFTDVNKFVT 61
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
I+ +F+EH E N YGTS SVR +++G +L + Q ++ +IFI
Sbjct 62 AISESQFLEHAEVFGNYYGTSEQSVRAQLDAGVDVILEIDWQGALQVKKIFTDAIMIFIL 121
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS LR L+ G++ + + EM Q FD I+N + A EL +
Sbjct 122 PPSIATLRQRLSTRGQDSMEVIEQRLAGAVNEMAQYVN--FDYVIINDSFEVALTELKAI 179
Query 659 I 659
I
Sbjct 180 I 180
>sp|Q0TPK6|KGUA_CLOP1 Guanylate kinase OS=Clostridium perfringens
(strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC
8237 / Type A) OX=195103 GN=gmk PE=3 SV=1
Length=216
Score = 238 bits (608), Expect = 2e-73, Method: Composition-based stats.
Identities = 54/186 (29%), Positives = 93/186 (50%), Gaps = 3/186 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
NR I++ GP G+ + + L+ K D F +V TTR+ R EV G +YHF+++
Sbjct 6 HKDNRGVLIVISGPSGAGKGTICKALLEKHDDIF-ISVSATTRNPRVGEVDGVNYHFLTK 64
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ F+ IA F+EH E N YGT SV ++++ GK +L + Q ++
Sbjct 65 EEFKQRIAEDDFLEHAEVYGNYYGTPKSSVEKMLDEGKNVILEIDIQGALKVKEKATDGV 124
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI PPS E L+ + K G + +E+ N ++ A+VN +++ A +
Sbjct 125 FIFILPPSMEELKQRIIKRGSETPESLMTRFKSAYKEI--NYVSKYNYAVVNDNVEDAVK 182
Query 654 ELLRLI 659
++ ++
Sbjct 183 KIEAIL 188
>sp|Q92AI1|KGUA_LISIN Guanylate kinase OS=Listeria innocua serovar
6a (strain ATCC BAA-680 / CLIP 11262) OX=272626 GN=gmk
PE=3 SV=1
Length=205
Score = 238 bits (607), Expect = 2e-73, Method: Composition-based stats.
Identities = 50/185 (27%), Positives = 86/185 (46%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
R I+L GP G+ +R+ + + F ++ TTR R+ E G DY+F SR+
Sbjct 2 TERGLLIVLSGPSGVGKGTVREAVFKDPETSFDYSISMTTRLPREGEQDGVDYYFRSREV 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I GK +E+ E+ N YGT ++ V + + +G L + Q +R + + I
Sbjct 62 FEQAIKDGKMLEYAEYVGNYYGTPLEYVEEKLAAGIDIFLEIEVQGAMQVRKAMPEGIFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP L+ + G + +E+E +D A+VN + KA Q++
Sbjct 122 FLTPPDLSELKNRIIGRGTESMEVVEERMETAKKEIEMMAS--YDYAVVNDVVSKAVQKI 179
Query 656 LRLIN 660
++
Sbjct 180 KGIVE 184
>sp|Q8XJK8|KGUA_CLOPE Guanylate kinase OS=Clostridium perfringens
(strain 13 / Type A) OX=195102 GN=gmk PE=3 SV=3
Length=216
Score = 238 bits (608), Expect = 3e-73, Method: Composition-based stats.
Identities = 53/186 (28%), Positives = 93/186 (50%), Gaps = 3/186 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
NR I++ GP G+ + + L+ K D F ++ TTR+ R EV G +YHF+++
Sbjct 6 HKDNRGVLIVISGPSGAGKGTICKALLEKHDDIF-ISISATTRNPRVGEVDGVNYHFLTK 64
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ F+ IA F+EH E N YGT SV ++++ GK +L + Q ++
Sbjct 65 EEFKQRIAEDDFLEHAEVYGNYYGTPKSSVEKMLDEGKNVILEIDIQGALKVKEKATDGV 124
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI PPS E L+ + K G + +E+ N ++ A+VN +++ A +
Sbjct 125 FIFILPPSMEELKQRIIKRGSETPESLMTRFKSAYKEI--NYVSKYNYAVVNDNVEDAVK 182
Query 654 ELLRLI 659
++ ++
Sbjct 183 KIEAIL 188
>sp|Q13V49|KGUA_PARXL Guanylate kinase OS=Paraburkholderia xenovorans
(strain LB400) OX=266265 GN=gmk PE=3 SV=1
Length=225
Score = 239 bits (609), Expect = 3e-73, Method: Composition-based stats.
Identities = 51/190 (27%), Positives = 84/190 (44%), Gaps = 3/190 (2%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A +++ P G++ L L+ + D ++ +TTR R +E+ G YHF +
Sbjct 17 AYPGNLFMVVAPSGAGKSTLVNALLAGD-DAIRLSISYTTRPPRPKELDGEHYHFTTVDD 75
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F AG+F+E E N YGTS + + SG LL + Q + ++ I
Sbjct 76 FMKRHDAGEFLESAEVHGNYYGTSRVWIEDQMKSGHDVLLEIDWQGAQQVKKQFHNAVEI 135
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS E L L K G++ R ++ EM + + ++N + D+A EL
Sbjct 136 FILPPSLEALEERLKKRGQDEPNVITRRLLAAGSEM--AHAAEAEYVVINENFDRALSEL 193
Query 656 LRLINKLDTE 665
L+ +
Sbjct 194 QCLVAATRSR 203
>sp|Q72ID5|KGUA_THET2 Guanylate kinase OS=Thermus thermophilus
(strain ATCC BAA-163 / DSM 7039 / HB27) OX=262724 GN=gmk PE=3
SV=1
Length=220
Score = 238 bits (608), Expect = 3e-73, Method: Composition-based stats.
Identities = 53/188 (28%), Positives = 92/188 (49%), Gaps = 4/188 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R R ++ G G+ +R +++ + R ++ TTR R EV G DY+FV R FE
Sbjct 2 RGRLFVMTGASGVGKGTVRAKVLER--TRLFYSISMTTRPPRPGEVDGVDYYFVDRPTFE 59
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
A + F+E+ E+ +LYGT V + ++ G+ LL + Q ++ + + +IF+
Sbjct 60 ALVREDGFLEYAEYVGHLYGTPRAPVERALSRGEDVLLEIEVQGALQVKRAVPEAVLIFL 119
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS L+ L GK+ + + + + E E N H FD +VN L++A + L
Sbjct 120 LPPSLSELKRRLVYRGKDSPEKIQKRLEQA--EWEIRNAHLFDYVVVNDVLEEAVADFLA 177
Query 658 LINKLDTE 665
++
Sbjct 178 ILTAERRR 185
>sp|P60552|KGUA_LACJO Guanylate kinase OS=Lactobacillus johnsonii
(strain CNCM I-12250 / La1 / NCC 533) OX=257314 GN=gmk PE=3
SV=1
Length=204
Score = 238 bits (606), Expect = 4e-73, Method: Composition-based stats.
Identities = 47/185 (25%), Positives = 87/185 (47%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A++ ++L GP G+ ++ ++ ++ F +V TTR R EV G+DY+FVS
Sbjct 2 AHQGLLLVLSGPSGVGKGTVKSAMVKQKAFSFEYSVSMTTRKPRPGEVNGKDYYFVSEDR 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F+ I + +E+ E+ N YGT + V++++N GK LL + K +R I
Sbjct 62 FQEAIKGNELLEYNEYVGNHYGTPLAPVQKMLNEGKDVLLEIDVNGAKQVRKLMPDGVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP L+ + G + + + +E+ +D A+VN + A +
Sbjct 122 FLTPPDLHELKHRIVNRGTDSDKVIAMRMKQARKEILMM--EDYDYAVVNDTVANAVDHI 179
Query 656 LRLIN 660
++
Sbjct 180 KSIVE 184
>sp|Q4UK55|KGUA_RICFE Guanylate kinase OS=Rickettsia felis (strain
ATCC VR-1525 / URRWXCal2) OX=315456 GN=gmk PE=3 SV=1
Length=192
Score = 237 bits (604), Expect = 4e-73, Method: Composition-based stats.
Identities = 50/183 (27%), Positives = 90/183 (49%), Gaps = 3/183 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N+ IIL P G++ L + L+ + + ++ TTR R EV G +Y+F ++ F
Sbjct 5 NKGLIIILSSPSGTGKSSLAKALLKID-NNLRLSISATTRKPRLGEVEGINYYFKTKLEF 63
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
E + KF+E+ + N YGT + V ++N G L + Q K+++ + IF
Sbjct 64 EELVKQNKFLEYAKIYDNYYGTPKEYVEMLLNQGLDVLFDIDWQGAKSIKKNATNVVAIF 123
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS E L L + EE ++ ++ + E ++ + +D I N D D+ +++
Sbjct 124 ILPPSIEILEQRLRNRATD--NEEAIKLRMQSAQNEMSHANEYDYVITNDDFDQTLKKIH 181
Query 657 RLI 659
+I
Sbjct 182 EII 184
>sp|Q92QZ2|KGUA_RHIME Guanylate kinase OS=Rhizobium meliloti (strain
1021) OX=266834 GN=gmk PE=3 SV=1
Length=219
Score = 238 bits (607), Expect = 5e-73, Method: Composition-based stats.
Identities = 52/189 (28%), Positives = 89/189 (47%), Gaps = 4/189 (2%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A R +++ P G++ + + L+ + D + +V TTRSRR E+ GR Y F S +
Sbjct 12 ARRGLMLVISSPSGAGKSTIARNLLEADPD-LSISVSVTTRSRRPSEIEGRHYFFKSIRE 70
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL-KPYI 594
FEA A +E E N YGT D+V + + G+ L + Q + L+
Sbjct 71 FEALRATDSLLEWAEVHGNYYGTPRDAVEKAMGEGRDMLFDIDWQGAQQLQEKMAGDVVS 130
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFI PPS L++ L + ++ + + E+E + +D +VN DLD+A+
Sbjct 131 IFILPPSMAELQSRLHRRAEDSEEVIATRLANSRAEIE--HWREYDYIVVNDDLDRAFSS 188
Query 655 LLRLINKLD 663
+ ++
Sbjct 189 VRAIVEAER 197
>sp|Q8XXF9|KGUA_RALN1 Guanylate kinase OS=Ralstonia nicotianae
(strain GMI1000) OX=267608 GN=gmk PE=3 SV=1
Length=221
Score = 238 bits (606), Expect = 5e-73, Method: Composition-based stats.
Identities = 47/188 (25%), Positives = 80/188 (43%), Gaps = 3/188 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+++ P G++ L L+ ++ +V TTR R E GR+Y+F++ F+A
Sbjct 20 GSLFMVVAPSGAGKSTLVNALLAQDPS-IRLSVSATTRKPRPGEQHGREYNFMTVDEFKA 78
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
G+F+E E N Y TS + + + +G LL + Q + + IFI
Sbjct 79 CRDRGEFLEWAEVHGNYYATSRVWIEEQMRAGTDVLLEIDWQGAQQVHRRFANAVEIFIL 138
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS L L K G++ +R ++ EM + D I+N + A EL +
Sbjct 139 PPSLTALEDRLKKRGQDEPNVIVRRLLAAGSEM--AHAPEADYVIINEVFEAALAELRTV 196
Query 659 INKLDTEP 666
+
Sbjct 197 VQAARLRY 204
>sp|Q49WZ1|KGUA_STAS1 Guanylate kinase OS=Staphylococcus saprophyticus
subsp. saprophyticus (strain ATCC 15305 / DSM 20229
/ NCIMB 8711 / NCTC 7292 / S-41) OX=342451 GN=gmk PE=3 SV=1
Length=207
Score = 237 bits (605), Expect = 6e-73, Method: Composition-based stats.
Identities = 51/187 (27%), Positives = 89/187 (48%), Gaps = 2/187 (1%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ I+L GP G+ +R+++ + + ++ TTR +R EV G DY F ++
Sbjct 1 MDNEKGLLIVLSGPSGVGKGTVRKKIFDDPSTSYKYSISMTTRDKRQGEVDGVDYFFKAK 60
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
FE I +FIE+ E+ N YGT + V+ ++ G L + + K +R
Sbjct 61 SEFEELIKQDQFIEYAEYVGNYYGTPVQYVKDTMDRGYDVFLEIEVEGAKQVRKKFPDAL 120
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+APPS + LR L G + + E +E+E N +D +VN +++ A Q
Sbjct 121 FIFLAPPSLDHLRERLVGRGTESSEKIQSRVHEARKEVEMMN--LYDYVVVNDEVELAKQ 178
Query 654 ELLRLIN 660
+ ++
Sbjct 179 RIQSIVE 185
>sp|Q3AWM1|KGUA_SYNS9 Guanylate kinase OS=Synechococcus sp. (strain
CC9902) OX=316279 GN=gmk PE=3 SV=2
Length=187
Score = 236 bits (603), Expect = 7e-73, Method: Composition-based stats.
Identities = 57/182 (31%), Positives = 91/182 (50%), Gaps = 3/182 (2%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A+ R +L GP G+ L +RL+++ + + +V TTR R E G Y F R
Sbjct 2 AHNGRLTVLTGPSGVGKGTLVKRLLDQHPEIW-LSVSATTRQPRAGEEEGVSYFFHPRDT 60
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F+A +AAG +E EF N YGT D V + + +G+ LL + + + +R S + +
Sbjct 61 FDALVAAGGLLEWAEFASNCYGTPRDPVEEHLAAGRPVLLEIELEGARQVRTSFPDAFQV 120
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+APPS L + G + + R + E+ N + FD +VN DLD+A ++L
Sbjct 121 FLAPPSFAELERRIRGRGTDTEDAIQRRLARAREEL--NAQNEFDAVVVNDDLDQALKQL 178
Query 656 LR 657
Sbjct 179 ET 180
>sp|Q9CEE3|KGUA_LACLA Guanylate kinase OS=Lactococcus lactis subsp.
lactis (strain IL1403) OX=272623 GN=gmk PE=3 SV=1
Length=205
Score = 237 bits (604), Expect = 7e-73, Method: Composition-based stats.
Identities = 51/184 (28%), Positives = 86/184 (47%), Gaps = 3/184 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R I+ GP G+ +R ++ E + F +V TTR +R EV G+DY+F +R F
Sbjct 3 ERGLLIVFSGPSGVGKGTVRAKIFESE-NNFEYSVSMTTRKQRPGEVDGKDYYFRTRDEF 61
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
E I G+ +E+ E+ N YGT + V Q ++ GK L + Q ++ +F
Sbjct 62 EEMIRNGQMLEYAEYVGNYYGTPLTYVNQTLDEGKDVFLEIEVQGALQVKEKVPDGVFVF 121
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+ PP E LR L G + + + E+ +D A+VN ++ A + +
Sbjct 122 LTPPDLEELRGRLVGRGTDSAEVIASRLEKAKEEIRLM--SEYDYAVVNDKVELAAERVK 179
Query 657 RLIN 660
++I
Sbjct 180 KIIE 183
>sp|Q9UDY2|ZO2_HUMAN Tight junction protein ZO-2 OS=Homo sapiens
OX=9606 GN=TJP2 PE=1 SV=2
Length=1190
Score = 259 bits (661), Expect = 8e-73, Method: Composition-based stats.
Identities = 88/443 (20%), Positives = 177/443 (40%), Gaps = 68/443 (15%)
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
R G K+VR +K + L N++ + ++ I +G +AE+ G L EGD+
Sbjct 497 RPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGGNDV-GIFVAGIQEGTSAEQEG-LQEGDQ 554
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK-----PPPAKETVIHVKAHFD 355
+L++N + RG + L ++ ++ + + +++HF+
Sbjct 555 ILKVNTQDFRGLVREDAVLYLLEIPKGEMVTILAQSRADVYRDILACGRGDSFFIRSHFE 614
Query 356 YDPSDDPYVPCRELGLSFQKGDILHVISQ---EDPNWWQAYREGDEDNQPLAGLVPGKSF 412
+ L+F +G++ V+ W A R G+E + GL+P KS
Sbjct 615 CEKETP-------QSLAFTRGEVFRVVDTLYDGKLGNWLAVRIGNELEK---GLIPNKSR 664
Query 413 QQQREAMKQTIEEDKEPEK-----SGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYE 467
+Q +++ ++ G+ KKN +K ++ L + + YE
Sbjct 665 AEQMASVQNAQRDNAGDRADFWRMRGQRSGVKKNLRKSREDLTAVVSV----STKFPAYE 720
Query 468 EMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRD 527
+ L + A KRP++L GP + ++L N+ D F +A + + + AG +
Sbjct 721 RVLL--REAGFKRPVVLFGPI---ADIAMEKLANELPDWFQTA-------KTEPKDAGSE 768
Query 528 YHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN 587
K+ +++VRQ+I K LL + +++ L
Sbjct 769 -------------------------KSTGVVRLNTVRQIIEQDKHALLDVTPKAVDLLNY 803
Query 588 SDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAI-VNS 646
+ P +IF P S++ ++ + + + R++ ++ ++++ H F I +NS
Sbjct 804 TQWFPIVIFFNPDSRQGVKTM-RQRLNPTSNKSSRKLFDQANKLKKTCAHLFTATINLNS 862
Query 647 DLDKAYQELLRLINKLDTEPQWV 669
D + L I E WV
Sbjct 863 ANDSWFGSLKDTIQHQQGEAVWV 885
Score = 51.2 bits (121), Expect = 3e-05, Method: Composition-based stats.
Identities = 21/99 (21%), Positives = 39/99 (39%), Gaps = 11/99 (11%)
Query 257 VRIEKARDIPLGATVR---------NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
V ++K G V N S++IS ++ GG A+ GLL E D V+ +NG
Sbjct 34 VTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPAD--GLLQENDRVVMVNGT 91
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKET 346
+ + L V+ ++++ + +
Sbjct 92 PMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQAS 130
Score = 50.1 bits (118), Expect = 6e-05, Method: Composition-based stats.
Identities = 24/102 (24%), Positives = 41/102 (40%), Gaps = 5/102 (5%)
Query 236 PITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLL 295
P + E G+ G V +++ + L + + + + G A K G L
Sbjct 290 PHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRL-----GSQIFVKEMTRTGLATKDGNL 344
Query 296 HEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
HEGD +L+ING + + L+ G L V++ Q
Sbjct 345 HEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQ 386
>sp|Q6F7H0|KGUA_ACIAD Guanylate kinase OS=Acinetobacter baylyi
(strain ATCC 33305 / BD413 / ADP1) OX=62977 GN=gmk PE=3 SV=1
Length=207
Score = 237 bits (604), Expect = 9e-73, Method: Composition-based stats.
Identities = 53/185 (29%), Positives = 84/185 (45%), Gaps = 3/185 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
++ G+ L + L+ + +V HTTR +R E+ G YHF +++ F +
Sbjct 3 GLLFVVSAASGTGKTSLVKALLERV-TNLHVSVSHTTRGQRPGELDGVHYHFTTKENFLS 61
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+ FIE+ E N YGTS +V+Q + G LL + Q + +R + IFI
Sbjct 62 QVEDNGFIEYAEVFGNYYGTSQATVKQQLAKGHDVLLEIDWQGAQQVRRIFPESKQIFIL 121
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPSQ LR L+ G + + +M+Q FD I+N D +KA +L +
Sbjct 122 PPSQFDLRQRLSNRGTDAVDVIEHRLSCAVEDMQQYVN--FDYIIINDDFNKALHDLESV 179
Query 659 INKLD 663
I
Sbjct 180 ITANR 184
>sp|P93757|GMK1_ARATH Guanylate kinase 1 OS=Arabidopsis thaliana
OX=3702 GN=GK-1 PE=1 SV=3
Length=387
Score = 243 bits (620), Expect = 9e-73, Method: Composition-based stats.
Identities = 68/231 (29%), Positives = 114/231 (49%), Gaps = 3/231 (1%)
Query 432 SGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQ--PANRKRPIILIGPQN 489
G++ KK + + + + ++ L +E+ + + N ++PI++ GP
Sbjct 88 QGRILVIKKGSPRNDSIWFLEVDSPYVREQKKLLRKEVVAWSKGVRGNAEKPIVISGPSG 147
Query 490 CGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHG 549
G+ L LM + F +V HTTRS R E+ G YHF ++ E +I GKF+E
Sbjct 148 VGKGTLISMLMKEFPSMFGFSVSHTTRSPRSMEMDGVHYHFADKKVMEKEIKDGKFLEFA 207
Query 550 EFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALL 609
NLYGTSI+SV V +SGK C+L + Q +++R S L IF+ PPS + L L
Sbjct 208 SVHGNLYGTSIESVEAVTDSGKRCILDIDVQGARSVRASSLDAIFIFVCPPSMKELEDRL 267
Query 610 AKEGKNPKPEELREIIEKTREM-EQNNGHYFDTAIVNSDLDKAYQELLRLI 659
G + + + + E+ E + F + N +L++ Y++L L+
Sbjct 268 RARGTETEEQIQKRLRNAEAEIKEGISSGIFGLILYNDNLEECYKKLKNLL 318
>sp|Q63RV7|KGUA_BURPS Guanylate kinase OS=Burkholderia pseudomallei
(strain K96243) OX=272560 GN=gmk PE=3 SV=1
Length=227
Score = 237 bits (605), Expect = 1e-72, Method: Composition-based stats.
Identities = 44/181 (24%), Positives = 78/181 (43%), Gaps = 3/181 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+++ P G++ L L++K+ + ++ +TTR R E G+ YHF + + F
Sbjct 21 GNLFMVVAPSGAGKSTLVNALLSKDPE-IRLSISYTTRKPRPGEQDGQHYHFTTVEDFRE 79
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
A +F+E E N YGTS + + + G LL + Q + ++ IFI
Sbjct 80 RHARHEFLESAEVHGNYYGTSRVWIEEQMKIGHDVLLEIDWQGAQQVKKQFRNAVGIFIL 139
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS L L K G++ R ++ E+ ++N + A EL +
Sbjct 140 PPSLAALEERLKKRGQDEPNVITRRLLAAGSEIAHAAEAQ--YVVINETFEHALAELECI 197
Query 659 I 659
+
Sbjct 198 V 198
>sp|Q3JPS9|KGUA_BURP1 Guanylate kinase OS=Burkholderia pseudomallei
(strain 1710b) OX=320372 GN=gmk PE=3 SV=1
Length=227
Score = 237 bits (605), Expect = 1e-72, Method: Composition-based stats.
Identities = 44/181 (24%), Positives = 78/181 (43%), Gaps = 3/181 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+++ P G++ L L++K+ + ++ +TTR R E G+ YHF + + F
Sbjct 21 GNLFMVVAPSGAGKSTLVNALLSKDPE-IRLSISYTTRKPRPGEQDGQHYHFTTVEDFRE 79
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
A +F+E E N YGTS + + + G LL + Q + ++ IFI
Sbjct 80 RHARHEFLESAEVHGNYYGTSRVWIEEQMKIGHDVLLEIDWQGAQQVKKQFRNAVGIFIL 139
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS L L K G++ R ++ E+ ++N + A EL +
Sbjct 140 PPSLAALEERLKKRGQDEPNVITRRLLAAGSEIAHAAEAQ--YVVINETFEHALAELECI 197
Query 659 I 659
+
Sbjct 198 V 198
>sp|Q62I00|KGUA_BURMA Guanylate kinase OS=Burkholderia mallei
(strain ATCC 23344) OX=243160 GN=gmk PE=3 SV=1
Length=227
Score = 237 bits (605), Expect = 1e-72, Method: Composition-based stats.
Identities = 44/181 (24%), Positives = 78/181 (43%), Gaps = 3/181 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+++ P G++ L L++K+ + ++ +TTR R E G+ YHF + + F
Sbjct 21 GNLFMVVAPSGAGKSTLVNALLSKDPE-IRLSISYTTRKPRPGEQDGQHYHFTTVEDFRE 79
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
A +F+E E N YGTS + + + G LL + Q + ++ IFI
Sbjct 80 RHARHEFLESAEVHGNYYGTSRVWIEEQMKIGHDVLLEIDWQGAQQVKKQFRNAVGIFIL 139
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS L L K G++ R ++ E+ ++N + A EL +
Sbjct 140 PPSLAALEERLKKRGQDEPNVITRRLLAAGSEIAHAAEAQ--YVVINETFEHALAELECI 197
Query 659 I 659
+
Sbjct 198 V 198
>sp|Q16774|KGUA_HUMAN Guanylate kinase OS=Homo sapiens OX=9606
GN=GUK1 PE=1 SV=2
Length=197
Score = 236 bits (602), Expect = 1e-72, Method: Composition-based stats.
Identities = 68/190 (36%), Positives = 107/190 (56%), Gaps = 1/190 (1%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
RP++L GP G++ L +RL+ + F +V HTTR+ R E G+DY+FV+R+ +
Sbjct 4 PRPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENGKDYYFVTREVMQR 63
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
DIAAG FIEH EF NLYGTS +V+ V +IC+L + Q ++ ++ +DL+P I +
Sbjct 64 DIAAGDFIEHAEFSGNLYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPIYISVQ 123
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQN-NGHYFDTAIVNSDLDKAYQELLR 657
PPS L L + + ++ + +ME + FD I+N LD+AY EL
Sbjct 124 PPSLHVLEQRLRQRNTETEESLVKRLAAAQADMESSKEPGLFDVVIINDSLDQAYAELKE 183
Query 658 LINKLDTEPQ 667
+++ + Q
Sbjct 184 ALSEEIKKAQ 193
>sp|Q182S8|KGUA_CLOD6 Guanylate kinase OS=Clostridioides difficile
(strain 630) OX=272563 GN=gmk PE=3 SV=1
Length=205
Score = 236 bits (602), Expect = 1e-72, Method: Composition-based stats.
Identities = 47/188 (25%), Positives = 89/188 (47%), Gaps = 3/188 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ +++ GP G+ + + L+ + D +V TTR R EV G +Y F+S++ FE
Sbjct 5 KGLLLVVSGPSGAGKGTICKELLKEN-DTIKLSVSATTRKPRTGEVDGVNYFFISKEKFE 63
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I G+F+E+ + N YGT ++ + + G+ LL + Q K ++ + IF+
Sbjct 64 EMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLEIEMQGAKQIKEVCPEGVFIFV 123
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS E L+ + G + E + E++ +D I N D+ + +E+
Sbjct 124 LPPSLEELKNRIVGRGTETEAEIEKRFSCAYEEIKMI--KDYDYFIFNEDVKTSAKEIEG 181
Query 658 LINKLDTE 665
+I+ +
Sbjct 182 IISSEKNK 189
>sp|Q39T72|KGUA_GEOMG Guanylate kinase OS=Geobacter metallireducens
(strain ATCC 53774 / DSM 7210 / GS-15) OX=269799 GN=gmk
PE=3 SV=1
Length=203
Score = 236 bits (601), Expect = 2e-72, Method: Composition-based stats.
Identities = 51/181 (28%), Positives = 82/181 (45%), Gaps = 3/181 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
I+ P G+ L + +++ +V +TTR R EV G+DY+F+S F +
Sbjct 5 GVLYIISAPSGAGKTTLCKEIIDIFP-HLRHSVSYTTRQPRAGEVHGKDYYFISMDEFRS 63
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+ G+F E E N YGTSI ++ + +G +L + Q + L+ IFI
Sbjct 64 MVDKGEFAEWAEVHGNCYGTSIRTLEECRITGIDLILDIDIQGARQLKERYEGGVYIFIL 123
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS E LR L + R I E+ + ++D IVN +A +EL +
Sbjct 124 PPSYEELRRRLNGRSSDSDDVISRRIDAAAGEIRE--SRWYDYIIVNDQFSRAVEELKSV 181
Query 659 I 659
+
Sbjct 182 V 182
>sp|Q88BE2|KGUA_PSESM Guanylate kinase OS=Pseudomonas syringae
pv. tomato (strain ATCC BAA-871 / DC3000) OX=223283 GN=gmk
PE=3 SV=1
Length=214
Score = 236 bits (601), Expect = 2e-72, Method: Composition-based stats.
Identities = 56/196 (29%), Positives = 91/196 (46%), Gaps = 9/196 (5%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKD-------RFASAVPHTTRSRRDQEVAGRDYHFV 531
I+ P G+ L + LM+ +++ + +V HTTR+ R EV G +Y+FV
Sbjct 6 GTLYIISAPSGAGKTSLVKALMDAQQEPQHGAQAKIRVSVSHTTRAMRPGEVDGVNYNFV 65
Query 532 SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK 591
R F I G F+E E NLYGTS ++Q ++ G +L + Q + +R +
Sbjct 66 DRAEFVRMIEHGDFLEQAEVFGNLYGTSQSHLQQTLDEGHDLILEIDWQGARQVRTQMPQ 125
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
IFI PPSQ+ LR L G++ + E EM ++ + ++ +VN D A
Sbjct 126 ARSIFILPPSQQALRQRLTNRGQDSDEIIEARMREAVSEM--SHYNEYEYVVVNDDFAGA 183
Query 652 YQELLRLINKLDTEPQ 667
++L + Q
Sbjct 184 LEDLKSIFRANRLTQQ 199
>sp|Q8DVK6|KGUA_STRMU Guanylate kinase OS=Streptococcus mutans
serotype c (strain ATCC 700610 / UA159) OX=210007 GN=gmk PE=3
SV=1
Length=210
Score = 236 bits (601), Expect = 2e-72, Method: Composition-based stats.
Identities = 50/185 (27%), Positives = 87/185 (47%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+ GP G+ +RQ + + +F +V TTR +R E+ G DY F +R+
Sbjct 2 SERGLLIVFSGPSGVGKGTVRQEIFSTPDHQFEYSVSMTTRPQRLGEIDGVDYFFRTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I G+ +E+ E+ N YGT + V + ++ G L + Q ++ I
Sbjct 62 FEELIKQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKQKVPDGVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP L+ L G + + + I E+ +E E +D A+VN ++ A + +
Sbjct 122 FLTPPDLAELKDRLVGRGTDSQEVIAQRI-ERAKE-EIALMREYDYAVVNDEVKLAAERV 179
Query 656 LRLIN 660
+I
Sbjct 180 KHIIE 184
>sp|Q5H3S2|KGUA_XANOR Guanylate kinase OS=Xanthomonas oryzae pv.
oryzae (strain KACC10331 / KXO85) OX=291331 GN=gmk PE=3 SV=1
Length=203
Score = 235 bits (600), Expect = 3e-72, Method: Composition-based stats.
Identities = 47/182 (26%), Positives = 82/182 (45%), Gaps = 3/182 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R I+ P G++ + + ++ + A ++ T+R+ R E YHFVS + F+
Sbjct 2 RGTLYIVAAPSGAGKSSIVNATLARDP-KIALSISFTSRAPRPGERHSEHYHFVSAEEFQ 60
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
IAAG F E+ + GT+ SV + +G LL + Q + +R +FI
Sbjct 61 GMIAAGDFFEYALVHGDWKGTARQSVEPQLAAGHDVLLEIDWQGARQVRQKVPDAVSVFI 120
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS++ L + K G++ + + + EM + FD I+N D A E+
Sbjct 121 LPPSRQALDERMRKRGQDSEDVMAQRLAAAREEM--LHFEEFDYVIINETFDTAVSEMCA 178
Query 658 LI 659
+
Sbjct 179 IF 180
>sp|Q2P6N0|KGUA_XANOM Guanylate kinase OS=Xanthomonas oryzae pv.
oryzae (strain MAFF 311018) OX=342109 GN=gmk PE=3 SV=1
Length=203
Score = 235 bits (600), Expect = 3e-72, Method: Composition-based stats.
Identities = 47/182 (26%), Positives = 82/182 (45%), Gaps = 3/182 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R I+ P G++ + + ++ + A ++ T+R+ R E YHFVS + F+
Sbjct 2 RGTLYIVAAPSGAGKSSIVNATLARDP-KIALSISFTSRAPRPGERHSEHYHFVSAEEFQ 60
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
IAAG F E+ + GT+ SV + +G LL + Q + +R +FI
Sbjct 61 GMIAAGDFFEYALVHGDWKGTARQSVEPQLAAGHDVLLEIDWQGARQVRQKVPDAVSVFI 120
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS++ L + K G++ + + + EM + FD I+N D A E+
Sbjct 121 LPPSRQALDERMRKRGQDSEDVMAQRLAAAREEM--LHFEEFDYVIINETFDTAVSEMCA 178
Query 658 LI 659
+
Sbjct 179 IF 180
>sp|Q8P5T7|KGUA_XANCP Guanylate kinase OS=Xanthomonas campestris
pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528
/ LMG 568 / P 25) OX=190485 GN=gmk PE=3 SV=1
Length=203
Score = 235 bits (599), Expect = 3e-72, Method: Composition-based stats.
Identities = 46/182 (25%), Positives = 81/182 (45%), Gaps = 3/182 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R I+ P G++ + + ++ + A ++ T+R+ R E YHFVS + F+
Sbjct 2 RGTLYIVAAPSGAGKSSIVNATLARDP-KIALSISFTSRAPRPGERHAEHYHFVSAEEFQ 60
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I AG F E+ + GT+ SV + +G LL + Q + +R +FI
Sbjct 61 GMIEAGDFFEYALVHGDWKGTARQSVEPQLAAGHDVLLEIDWQGARQVRQKVPDAVSVFI 120
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS++ L + K G++ + + + EM + FD I+N D A E+
Sbjct 121 LPPSRQALDERMRKRGQDSEDVMAQRLAAAREEM--LHFEEFDYVIINETFDTAVSEMCA 178
Query 658 LI 659
+
Sbjct 179 IF 180
>sp|Q4UY41|KGUA_XANC8 Guanylate kinase OS=Xanthomonas campestris
pv. campestris (strain 8004) OX=314565 GN=gmk PE=3 SV=1
Length=203
Score = 235 bits (599), Expect = 3e-72, Method: Composition-based stats.
Identities = 46/182 (25%), Positives = 81/182 (45%), Gaps = 3/182 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R I+ P G++ + + ++ + A ++ T+R+ R E YHFVS + F+
Sbjct 2 RGTLYIVAAPSGAGKSSIVNATLARDP-KIALSISFTSRAPRPGERHAEHYHFVSAEEFQ 60
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I AG F E+ + GT+ SV + +G LL + Q + +R +FI
Sbjct 61 GMIEAGDFFEYALVHGDWKGTARQSVEPQLAAGHDVLLEIDWQGARQVRQKVPDAVSVFI 120
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS++ L + K G++ + + + EM + FD I+N D A E+
Sbjct 121 LPPSRQALDERMRKRGQDSEDVMAQRLAAAREEM--LHFEEFDYVIINETFDTAVSEMCA 178
Query 658 LI 659
+
Sbjct 179 IF 180
>sp|Q7VRJ7|KGUA_BLOFL Guanylate kinase OS=Blochmannia floridanus
OX=203907 GN=gmk PE=3 SV=1
Length=210
Score = 235 bits (599), Expect = 4e-72, Method: Composition-based stats.
Identities = 53/192 (28%), Positives = 94/192 (49%), Gaps = 5/192 (3%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEK-DRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
I+ P G++ L L + + ++ +TTR +R EV G+DY+F+S + F+
Sbjct 6 GLLGIISAPSGAGKSTLINALQKNDSILQIKLSISYTTRKKRPGEVHGKDYYFISIEEFQ 65
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I F+E+ + + YGT +S++ ++NSG +L++ Q + +RN L Y IFI
Sbjct 66 NMINQNMFLEYAKVFNHYYGTEKNSIKLMLNSGVHVILNIDWQGMNQIRNKKLDFYTIFI 125
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPSQ+ L L G + + + E+ ++ +D I+N D + A L
Sbjct 126 LPPSQKELEKRLRFRGLDTDQVIFDRMKQAMNEI--SHCKEYDYIIINDDFNIALIYLQS 183
Query 658 LI--NKLDTEPQ 667
+I +L + Q
Sbjct 184 VILSKQLKIDYQ 195
>sp|Q2KA85|KGUA_RHIEC Guanylate kinase OS=Rhizobium etli (strain
CFN 42 / ATCC 51251) OX=347834 GN=gmk PE=3 SV=1
Length=220
Score = 235 bits (600), Expect = 5e-72, Method: Composition-based stats.
Identities = 48/191 (25%), Positives = 84/191 (44%), Gaps = 4/191 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
Q A R +++ P G++ + + L+ +K +V TTR RR EV G YHF S
Sbjct 10 QIARRGLMLVISSPSGAGKSTIARTLLETDK-HIGLSVSVTTRPRRPSEVEGVHYHFKSV 68
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD-LKP 592
+ FE + +E E N YGT + V Q + G+ L + Q + L+
Sbjct 69 REFERLRDSDALLEWAEVHGNFYGTPREPVEQAMAEGRDMLFDIDWQGAQQLQEKMSADV 128
Query 593 YIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAY 652
IF+ PP+ L++ L + ++ + + E+ + +D IVN DL+ A+
Sbjct 129 VSIFVLPPTMTELQSRLHRRAEDSEEVIQTRLANSRAEI--AHWREYDYVIVNDDLNTAF 186
Query 653 QELLRLINKLD 663
+ ++
Sbjct 187 DAVQSIVKAER 197
>sp|Q5WV30|KGUA_LEGPL Guanylate kinase OS=Legionella pneumophila
(strain Lens) OX=297245 GN=gmk PE=3 SV=1
Length=209
Score = 234 bits (598), Expect = 5e-72, Method: Composition-based stats.
Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 5/193 (3%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N I+ P G+ L ++L+ + +V HTTR R E G DY F+ + F
Sbjct 5 NSGNLYIVAAPSGGGKTSLVKKLI-EMVGEIEVSVSHTTRPMRPGEKEGVDYFFIDEEQF 63
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ + G FIEH + + YGTS+ + + + G +L + Q + +R++ +F
Sbjct 64 ISMVNEGAFIEHAKVFNHWYGTSVAQINKRLQFGIDVVLDIDWQGAEQIRHAYPDAVSVF 123
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS + L+ L ++ + + E+ + FD IVN D +KA EL
Sbjct 124 IIPPSLDALKERLMNRRQDKDNVISERMTKAQDEL--GHYPEFDYLIVNDDFEKAAMELQ 181
Query 657 RLI--NKLDTEPQ 667
++ N+L E Q
Sbjct 182 SIVIANRLRIEKQ 194
>sp|Q9K9Y2|KGUA_HALH5 Guanylate kinase OS=Halalkalibacterium halodurans
(strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM
9153 / C-125) OX=272558 GN=gmk PE=3 SV=1
Length=204
Score = 234 bits (598), Expect = 6e-72, Method: Composition-based stats.
Identities = 52/186 (28%), Positives = 84/186 (45%), Gaps = 3/186 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ I+L GP G+ + L K +V TTR+ R EV G +Y F SR
Sbjct 1 MEKEKGLLIVLSGPAGVGKGTVCSAL-RKHDTNIQYSVSATTRAPRKGEVDGVNYFFKSR 59
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ FEA I + +E E+ N YGT I VR+ I+SGK +L + Q +R +
Sbjct 60 EQFEAMIEKEELLEWAEYVGNYYGTPIQYVRETIDSGKDIILEIEVQGALKVRERFPEGV 119
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+ PPS LR+ + G + + + E+E +D + N +++ A
Sbjct 120 FIFLMPPSLAELRSRIVGRGTETEEVINKRMNVAKEEIEMM--KKYDYVVENDEVELAVD 177
Query 654 ELLRLI 659
+ ++
Sbjct 178 RIKAIV 183
>sp|Q1RK99|KGUA_RICBR Guanylate kinase OS=Rickettsia bellii (strain
RML369-C) OX=336407 GN=gmk PE=3 SV=1
Length=191
Score = 234 bits (596), Expect = 6e-72, Method: Composition-based stats.
Identities = 45/192 (23%), Positives = 86/192 (45%), Gaps = 3/192 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
N+ IIL P G++ L + L+ + ++ TTR R E G +Y+F ++
Sbjct 1 MTKNKGLIIILSSPSGAGKSSLAKALLEID-HNLRLSISATTRKPRPNEQDGVNYYFKTK 59
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
FE + +F+EH + N YGT V ++N G L + Q ++++ + +
Sbjct 60 VEFEKLVKQNQFLEHAKIYDNYYGTPKKHVENLLNQGLDVLFDIDWQGARSIKQNAVNAV 119
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI PP+ E L L + + + + + E ++ + +D I N D + Q
Sbjct 120 SIFILPPNLEVLEQRLRNRAADNEEAIQLRM--ASAQAEISHSNEYDHIITNDDFNDTIQ 177
Query 654 ELLRLINKLDTE 665
++ +I + +
Sbjct 178 QIHTIILQERKK 189
>sp|Q135N9|KGUA_RHOPS Guanylate kinase OS=Rhodopseudomonas palustris
(strain BisB5) OX=316057 GN=gmk PE=3 SV=1
Length=219
Score = 234 bits (598), Expect = 7e-72, Method: Composition-based stats.
Identities = 52/194 (27%), Positives = 89/194 (46%), Gaps = 6/194 (3%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R +L P G+ L + L+++ +V TTR RR EV GRDY+FV R F
Sbjct 13 RRGLMFVLSSPSGAGKTTLSRMLVDEAPG-LTMSVSATTRPRRPGEVDGRDYYFVDRPKF 71
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-I 595
+A + A +F+E N YGT V + +G+ L + Q + LR+ + +
Sbjct 72 DAMVEADEFLEWAHVFDNCYGTPRAPVEAALAAGRDVLFDIDWQGTQQLRSRASNDVVSV 131
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS + L L ++ + + EM ++ +D +VN ++ A++ +
Sbjct 132 FILPPSVQDLEHRLHTRAQDSDEVIRGRMKKAGDEM--SHFDAYDYIVVNDNIGVAFESV 189
Query 656 LRLI--NKLDTEPQ 667
++ +L E Q
Sbjct 190 KAILRAEQLKRERQ 203
>sp|Q9M682|GMK2_ARATH Guanylate kinase 2 OS=Arabidopsis thaliana
OX=3702 GN=GK-2 PE=2 SV=1
Length=389
Score = 241 bits (614), Expect = 9e-72, Method: Composition-based stats.
Identities = 67/240 (28%), Positives = 111/240 (46%), Gaps = 3/240 (1%)
Query 431 KSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQ--PANRKRPIILIGPQ 488
G++ KK + + ++ L E+ + + N ++PI++ GP
Sbjct 87 PKGRILVIKKGSASDDSIWFLEVDTPFIREQKKLLGREVVAWSKGVRGNAEKPIVISGPS 146
Query 489 NCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEH 548
G+ L LM + F +V HTTR+ R E G YHF + E +I GKF+E
Sbjct 147 GVGKGTLISMLMKEFPSMFGFSVSHTTRAPRCMEKNGVHYHFTDKTVMEKEIKDGKFLEF 206
Query 549 GEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRAL 608
NLYGTSI+SV V +SGK C+L + Q ++++ S L IF+ PPS + L
Sbjct 207 ASVHGNLYGTSIESVEVVTDSGKRCILDIDVQGARSVKASSLDAIFIFVCPPSMKELEDR 266
Query 609 LAKEGKNPKPEELREIIEKTREMEQ-NNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQ 667
L G + + + + E++ + F+ + N +L++ Y+ L L+ D P
Sbjct 267 LRARGTETEEQIQKRLRNADAEIKAGKSSGIFEHKLYNDNLEECYKTLKNLLGINDLAPV 326
>sp|Q5X3P2|KGUA_LEGPA Guanylate kinase OS=Legionella pneumophila
(strain Paris) OX=297246 GN=gmk PE=3 SV=1
Length=209
Score = 234 bits (597), Expect = 1e-71, Method: Composition-based stats.
Identities = 54/193 (28%), Positives = 89/193 (46%), Gaps = 5/193 (3%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N I+ P G+ L ++L+ + +V HTTR R E G DY F+ + F
Sbjct 5 NSGNLYIVAAPSGGGKTSLVKKLI-EMVGEIEVSVSHTTRPMRPGEKEGVDYFFIDEEQF 63
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ + G FIEH + + YGTS+ + + + G +L + Q + +R+S +F
Sbjct 64 ISMVNEGAFIEHAKVFNHWYGTSVAQINKRLQFGIDVVLDIDWQGAEQIRHSYPDAVSVF 123
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS + L+ L ++ + + E+ + FD IVN D +KA EL
Sbjct 124 IIPPSLDTLKERLMNRRQDKDNVISERMTKAQDEL--GHYPEFDYLIVNDDFEKAAMELQ 181
Query 657 RLI--NKLDTEPQ 667
++ N+L E Q
Sbjct 182 SIVIANRLRIEKQ 194
>sp|Q8PH65|KGUA_XANAC Guanylate kinase OS=Xanthomonas axonopodis
pv. citri (strain 306) OX=190486 GN=gmk PE=3 SV=1
Length=203
Score = 234 bits (596), Expect = 1e-71, Method: Composition-based stats.
Identities = 46/182 (25%), Positives = 80/182 (44%), Gaps = 3/182 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R I+ P G++ + + ++ + A ++ T+R+ R E YHFVS F+
Sbjct 2 RGTLYIVAAPSGAGKSSIVNATLARDP-KIALSISFTSRAPRPGERHAEHYHFVSADEFQ 60
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I AG F E+ + GT+ SV + +G LL + Q + +R +FI
Sbjct 61 GMIEAGDFFEYALVHGDWKGTARQSVEPQLAAGHDVLLEIDWQGARQVRQKVPDAVSVFI 120
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS++ L + K G++ + + + EM + FD I+N D A E+
Sbjct 121 LPPSRQALDERMRKRGQDSEVVMAQRLAAAREEM--LHFEEFDYVIINETFDTAVSEMCA 178
Query 658 LI 659
+
Sbjct 179 IF 180
>sp|Q895Q5|KGUA_CLOTE Guanylate kinase OS=Clostridium tetani (strain
Massachusetts / E88) OX=212717 GN=gmk PE=3 SV=1
Length=208
Score = 234 bits (596), Expect = 1e-71, Method: Composition-based stats.
Identities = 47/184 (26%), Positives = 91/184 (49%), Gaps = 4/184 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I++ GP G+ + + L+ + F +V TTR R+ E+ G+ Y+F+S++ F
Sbjct 2 EKGLLIVISGPSGTGKGTVCKELLRN--NNFWFSVSSTTRDPREGEIQGKSYYFMSKEEF 59
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
E I F+E+ + N YGT V ++++ GK +L + Q ++ + + IF
Sbjct 60 EDKIKENDFLEYAKVYGNYYGTPKSKVIEMLDKGKDVILEIDIQGALQVKENYKEGIFIF 119
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS E L+ + K G + + +E+ N ++ A+VN + A +++
Sbjct 120 ILPPSMEELKNRIIKRGTETEESLMTRFKSAYKEI--NYVSKYNYAVVNDKVHDAVEKIQ 177
Query 657 RLIN 660
+I+
Sbjct 178 SIIS 181
>sp|Q9P6I5|KGUA_SCHPO Guanylate kinase OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=SPBC1198.05 PE=3
SV=1
Length=202
Score = 233 bits (595), Expect = 1e-71, Method: Composition-based stats.
Identities = 59/182 (32%), Positives = 101/182 (55%), Gaps = 1/182 (1%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ +P+++ GP G++ L +RL+ D+ +V HTTR+ R E G DYHFV+++ F+
Sbjct 17 KLKPVVVFGPSGVGKSTLLKRLLKDHGDKLGFSVSHTTRTPRAGEKDGIDYHFVTKEEFQ 76
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
+A KF+E F N+YGTSI +++++ K +L + Q + ++ S + +F+
Sbjct 77 KLVAEEKFVEWAVFSGNMYGTSIMAIQELEAVNKKAILDIDLQGVLQVKASPIDAQYVFL 136
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREME-QNNGHYFDTAIVNSDLDKAYQELL 656
APPS E+L L G + L+ + E+E FD IVN D++KAY++L
Sbjct 137 APPSIEQLEVRLRGRGTENESAILQRLERARAEIEYSEKPGNFDALIVNDDVEKAYKQLE 196
Query 657 RL 658
+
Sbjct 197 AI 198
>sp|Q2YD10|KGUA_NITMU Guanylate kinase OS=Nitrosospira multiformis
(strain ATCC 25196 / NCIMB 11849 / C 71) OX=323848 GN=gmk
PE=3 SV=1
Length=210
Score = 234 bits (596), Expect = 1e-71, Method: Composition-based stats.
Identities = 57/199 (29%), Positives = 95/199 (48%), Gaps = 5/199 (3%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
I+ P G+ L + L+ D + ++ +T+R R +E+ GRDYHFV+R
Sbjct 1 MTTTPGTLYIISAPSGAGKTSLVKALLQTGID-LSLSISYTSRQPRPEEMDGRDYHFVTR 59
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
Q FE + +F+E E N YGTS + + + SG+ LL + +Q + +R
Sbjct 60 QVFEQKLQEDEFLESAELYGNFYGTSKKWINETMTSGRDILLEIDSQGARQVRAVFPVAV 119
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+ PPS E L L + ++ R + E+ ++ ++ I+N LD+A Q
Sbjct 120 GIFVLPPSLEVLEMRLRQRAQDSLEAISRRLAAAREEL--SHAGEYNYIIINDKLDRALQ 177
Query 654 ELLRLIN--KLDTEPQWVP 670
+L +I +L T Q V
Sbjct 178 DLKCIIQAERLKTAKQLVR 196
>sp|Q3BPS0|KGUA_XANC5 Guanylate kinase OS=Xanthomonas campestris
pv. vesicatoria (strain 85-10) OX=316273 GN=gmk PE=3 SV=1
Length=203
Score = 233 bits (595), Expect = 1e-71, Method: Composition-based stats.
Identities = 46/182 (25%), Positives = 80/182 (44%), Gaps = 3/182 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R I+ P G++ + + ++ + A ++ T+R+ R E YHFVS F+
Sbjct 2 RGTLYIVAAPSGAGKSSIVNATLARDP-KIALSISFTSRAPRPGERHAEHYHFVSADEFQ 60
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I AG F E+ + GT+ SV + +G LL + Q + +R +FI
Sbjct 61 GMIEAGDFFEYALVHGDWKGTARQSVEPQLAAGHDVLLEIDWQGARQVRQKVPDAVSVFI 120
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS++ L + K G++ + + + EM + FD I+N D A E+
Sbjct 121 LPPSRQALDERMRKRGQDSEDVMAQRLAAAREEM--LHFEEFDYVIINETFDIAVAEMCA 178
Query 658 LI 659
+
Sbjct 179 IF 180
>sp|P31006|KGUA_PIG Guanylate kinase OS=Sus scrofa OX=9823 GN=GUK1
PE=1 SV=2
Length=198
Score = 233 bits (595), Expect = 1e-71, Method: Composition-based stats.
Identities = 69/190 (36%), Positives = 106/190 (56%), Gaps = 1/190 (1%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
RP++L GP G++ L ++L+ + F +V HTTR R E G+DY+FV+R+ +
Sbjct 4 PRPVVLSGPSGAGKSTLLKKLLQEHSSIFGFSVSHTTRDPRPGEENGKDYYFVTREVMQR 63
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
DIAAG FIEH EF NLYGTS +VR V +IC+L + Q ++ ++ +DL+P IF+
Sbjct 64 DIAAGDFIEHAEFSGNLYGTSKAAVRAVQAMNRICVLDVDLQGVRNIKKTDLQPIYIFVQ 123
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQN-NGHYFDTAIVNSDLDKAYQELLR 657
PPS + L L + + + + +ME + FD I+N LDKAY L
Sbjct 124 PPSLDVLEQRLRQRNTETEESLAKRLAAAKADMESSKEPGLFDLIIINDSLDKAYWALKE 183
Query 658 LINKLDTEPQ 667
+++ + Q
Sbjct 184 ALSEEIKKAQ 193
>sp|Q0VT94|KGUA_ALCBS Guanylate kinase OS=Alcanivorax borkumensis
(strain ATCC 700651 / DSM 11573 / NCIMB 13689 / SK2) OX=393595
GN=gmk PE=3 SV=1
Length=207
Score = 233 bits (595), Expect = 1e-71, Method: Composition-based stats.
Identities = 55/188 (29%), Positives = 85/188 (45%), Gaps = 3/188 (2%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A++ I+ P G+ L L++K + ++ HTTR+ R E G +YHF R
Sbjct 2 ADKGTLYIISAPSGAGKTSLVAALVDKL-AQVRISISHTTRAMRPGEKDGVNYHFTDRDC 60
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F + G+F+EH + NLYGTS D V Q + +G +L + Q +R I
Sbjct 61 FVRQVEQGRFLEHAQVFGNLYGTSADWVAQTLRTGDDVILEIDWQGATQIRKQLPDSVSI 120
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS E L L + + + + EM ++ FD +VN D +A EL
Sbjct 121 FILPPSLEALAGRLRGRETDDETVIQQRLDGAQEEM--SHYGEFDYLVVNDDFQRALYEL 178
Query 656 LRLINKLD 663
++
Sbjct 179 EAIVEARR 186
>sp|P60556|KGUA_RHOPA Guanylate kinase OS=Rhodopseudomonas palustris
(strain ATCC BAA-98 / CGA009) OX=258594 GN=gmk PE=3 SV=1
Length=220
Score = 234 bits (596), Expect = 2e-71, Method: Composition-based stats.
Identities = 52/199 (26%), Positives = 86/199 (43%), Gaps = 6/199 (3%)
Query 472 YHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFV 531
Y R +L P G+ L + L+ + +V TTR R EV GRDY+FV
Sbjct 9 YSGVERRGLMFVLSSPSGAGKTTLSRMLVEQMPG-LQMSVSATTRPMRPGEVDGRDYYFV 67
Query 532 SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLR-NSDL 590
R F+ + AG+F+E N YGT V + G+ L + Q + LR +
Sbjct 68 DRPKFDEMVGAGEFLEWANVFDNRYGTPRAPVEAALAVGRDVLFDIDWQGTQQLRSRAGS 127
Query 591 KPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDK 650
+FI PPS + L L ++ + + EM ++ +D +VN ++
Sbjct 128 DVVSVFILPPSVQALEHRLHTRAQDSHEVIRGRMKKAGDEM--SHFDAYDYIVVNDNIGV 185
Query 651 AYQELLRLI--NKLDTEPQ 667
A++ + ++ +L E Q
Sbjct 186 AFESVRSILRAEQLKRERQ 204
>sp|Q30XT1|KGUA_OLEA2 Guanylate kinase OS=Oleidesulfovibrio alaskensis
(strain ATCC BAA-1058 / DSM 17464 / G20) OX=207559
GN=gmk PE=3 SV=1
Length=206
Score = 233 bits (595), Expect = 2e-71, Method: Composition-based stats.
Identities = 60/177 (34%), Positives = 89/177 (50%), Gaps = 3/177 (2%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++L P G+ L +RL+ + RFA +V +TTR R E GR+Y+FV + F
Sbjct 10 LVLCAPSGTGKTTLTRRLLEEFP-RFAFSVSYTTRQPRAGEEHGREYNFVDEETFIRLRD 68
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G F E E N YGT ++ RQ++ G+ L + Q LR S + +FI PPS
Sbjct 69 EGFFAEWAEVHGNFYGTPLEDTRQLLARGRDVLFDIDVQGAAQLRGSLKQGCYVFILPPS 128
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
L L G +P+ R + RE++Q H+F+ IVN +L++AY EL
Sbjct 129 GAELERRLRARGTDPEDTIRRRLANARRELQQ--AHWFNAWIVNDNLEQAYDELRAA 183
>sp|Q7U570|KGUA_PARMW Guanylate kinase OS=Parasynechococcus marenigrum
(strain WH8102) OX=84588 GN=gmk PE=3 SV=1
Length=182
Score = 232 bits (592), Expect = 2e-71, Method: Composition-based stats.
Identities = 56/181 (31%), Positives = 89/181 (49%), Gaps = 3/181 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
++ GP G+ L QRL+ + + +V TTR+ R+ E G Y F SR+ F+A
Sbjct 2 GTLTVITGPSGVGKGTLVQRLLARNPSIW-VSVSATTRAPREGEREGESYFFHSRERFDA 60
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+ G +E EF N YGT V Q + +G+ LL + + + +R S K IF+A
Sbjct 61 LVQEGGLLEWAEFAGNCYGTPRAPVEQQLQAGRPVLLEIELEGARQVRRSFSKARQIFLA 120
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS E L + G + + + ++ E+ + FD +VN DLD+A +L L
Sbjct 121 PPSFEELERRIRGRGTDSEDAIQQRLLRAREEL--SAQGEFDAVVVNDDLDQALLKLEGL 178
Query 659 I 659
+
Sbjct 179 M 179
>sp|Q11HG8|KGUA_CHESB Guanylate kinase OS=Chelativorans sp. (strain
BNC1) OX=266779 GN=gmk PE=3 SV=1
Length=218
Score = 234 bits (596), Expect = 2e-71, Method: Composition-based stats.
Identities = 52/198 (26%), Positives = 87/198 (44%), Gaps = 4/198 (2%)
Query 467 EEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGR 526
E S R ++L P G++ + + L+ + F +V TTR RR E+ G
Sbjct 2 ESASPSATIRRRGVMLVLSSPSGAGKSTIARSLL-ENDHEFELSVSVTTRPRRPSEIEGV 60
Query 527 DYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLR 586
YHF +++ FE G +E E N YGT V + I G+ L + Q LR
Sbjct 61 HYHFKTQRDFEMMRDGGDLLEWAEVHGNCYGTPRGPVERAIAGGRDMLFDIDWQGAAQLR 120
Query 587 NSDLKPYI-IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVN 645
+ +FI PP+ + L A L + ++ R + E+EQ +D ++N
Sbjct 121 EKMPDDIVSVFILPPTMKELLARLTRRAEDTPEIIERRLRNAHHEIEQ--WRDYDYVVIN 178
Query 646 SDLDKAYQELLRLINKLD 663
DLD+A+ + +++
Sbjct 179 DDLDRAFASVRAIVSAER 196
>sp|Q6G439|KGUA_BARHE Guanylate kinase OS=Bartonella henselae
(strain ATCC 49882 / DSM 28221 / CCUG 30454 / Houston 1) OX=283166
GN=gmk PE=1 SV=1
Length=222
Score = 234 bits (596), Expect = 2e-71, Method: Composition-based stats.
Identities = 52/199 (26%), Positives = 96/199 (48%), Gaps = 7/199 (4%)
Query 463 ILTYEEMSLYHQPANRKR--PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRD 520
++T+ E L + N++R IL P G++ L + L+ + ++ TTR +R
Sbjct 1 MVTFFENELSAKKRNQRRGFLFILSSPSGAGKSTLSRLLLKD--GKLELSISMTTRQKRP 58
Query 521 QEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQ 580
EV G YHF+S++ F+ +FIE E N YGT +SV V+++G+ L + Q
Sbjct 59 SEVDGLHYHFISKKEFKRKRDGNEFIEWAEVHGNYYGTLRESVENVLSTGRDMLFDIDYQ 118
Query 581 SLKTLRNSDL-KPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYF 639
K L+ +FI PPS + L + L + ++ + + EM+ + +
Sbjct 119 GTKQLQKKMPGDTVSVFILPPSMKELISRLYRRAEDSQDIINLRLKNARTEMQ--HWRSY 176
Query 640 DTAIVNSDLDKAYQELLRL 658
D I+N +L+++ + +
Sbjct 177 DYVIINENLNQSVSLIKSI 195
>sp|Q5LS25|KGUA_RUEPO Guanylate kinase OS=Ruegeria pomeroyi (strain
ATCC 700808 / DSM 15171 / DSS-3) OX=246200 GN=gmk PE=3
SV=1
Length=213
Score = 233 bits (595), Expect = 2e-71, Method: Composition-based stats.
Identities = 59/200 (30%), Positives = 95/200 (48%), Gaps = 5/200 (3%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
R IIL P G++ L +RLM+ + +V TTR+ R E GR+Y+F+S
Sbjct 1 MTDRRGLLIILSSPSGAGKSTLARRLMSWDPG-LKFSVSATTRAPRPGEEHGREYYFLSE 59
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL--K 591
F+ + G+ +EH N YG+ VR I +G+ L + Q +RNSDL
Sbjct 60 DQFKGQVRRGEMLEHAHVFGNFYGSPAGPVRDTIEAGQDVLFDVDWQGEIQIRNSDLGKH 119
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
IFI PPS + LR L G++ R +++ E+ ++ Y+D ++N DLD
Sbjct 120 ALSIFILPPSIKELRRRLESRGQDSAEVISRRMLKSWDEI--SHWGYYDYVLINDDLDAT 177
Query 652 YQELLRLINKLDTEPQWVPS 671
+ L +++ P+
Sbjct 178 EERLKTIVSAERMRRIQQPA 197
>sp|Q9ZCH7|KGUA_RICPR Guanylate kinase OS=Rickettsia prowazekii
(strain Madrid E) OX=272947 GN=gmk PE=3 SV=1
Length=197
Score = 233 bits (593), Expect = 2e-71, Method: Composition-based stats.
Identities = 43/183 (23%), Positives = 90/183 (49%), Gaps = 3/183 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N+ IIL P G++ L + L+ + + ++ TTR R EV G +Y+F S + F
Sbjct 5 NKGLIIILSSPSGTGKSSLAKELLKID-NNLRLSISVTTRKPRLGEVDGINYYFKSDREF 63
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ + KF+E+ + + YGT + V+ ++ G L + Q +++++ + IF
Sbjct 64 KTLVKQNKFLEYAKIYNDYYGTPKEYVKMLLKQGFDVLFDIDWQGVRSIKKNTNNVITIF 123
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS E L L + + ++ ++ + E ++ + +D ++N D + +++
Sbjct 124 ILPPSIEILEQRLRNRATDNEETI--KLRMQSAQNEISHANEYDYVVINDDFSQTLKKIH 181
Query 657 RLI 659
+I
Sbjct 182 EII 184
>sp|P46195|KGUA_BOVIN Guanylate kinase OS=Bos taurus OX=9913 GN=GUK1
PE=1 SV=2
Length=198
Score = 233 bits (593), Expect = 2e-71, Method: Composition-based stats.
Identities = 70/190 (37%), Positives = 106/190 (56%), Gaps = 1/190 (1%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
RP++L GP G++ L ++L+ + F +V HTTR R E G+DY+FV+R+ +
Sbjct 4 PRPVVLSGPSGAGKSTLLKKLLQEHGSIFGFSVSHTTRDPRPGEENGKDYYFVTREVMQR 63
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
DIAAG FIEH EF NLYGTS +VR V +IC+L + Q ++ ++ +DL+P IF+
Sbjct 64 DIAAGDFIEHAEFSGNLYGTSKAAVRAVQAMNRICVLDVDLQGVRNIKKTDLRPIYIFVQ 123
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQN-NGHYFDTAIVNSDLDKAYQELLR 657
PPS + L L + + + + +ME + FD IVN LDKAY L
Sbjct 124 PPSLDVLEQRLRQRNTETEESLAKRLAAARADMESSKEPGLFDLIIVNDSLDKAYWALKE 183
Query 658 LINKLDTEPQ 667
+++ + Q
Sbjct 184 ALSEEIKKAQ 193
>sp|Q2IX83|KGUA_RHOP2 Guanylate kinase OS=Rhodopseudomonas palustris
(strain HaA2) OX=316058 GN=gmk PE=3 SV=1
Length=220
Score = 233 bits (595), Expect = 2e-71, Method: Composition-based stats.
Identities = 52/194 (27%), Positives = 90/194 (46%), Gaps = 6/194 (3%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R +L P G+ L + L+++ +V TTR +R EV GRDY+FV R F
Sbjct 14 RRGLMFVLSSPSGAGKTTLSRMLVDEAPG-LRMSVSATTRPKRPGEVDGRDYYFVDRPKF 72
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-I 595
+A + AG+F+E N YGT V +++G L + Q + LR+ + +
Sbjct 73 DAMVEAGEFLEWANVFDNCYGTPRAPVEAALSAGNDVLFDIDWQGTQQLRSRASNDVVSV 132
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS + L L ++ + + EM ++ +D +VN ++ A++ +
Sbjct 133 FILPPSVQDLEHRLHTRAQDSDEVIRGRMKKAGDEM--SHFDAYDYIVVNDNIGVAFESV 190
Query 656 LRLI--NKLDTEPQ 667
++ +L E Q
Sbjct 191 KAILRAEQLKRERQ 204
>sp|Q21TP7|KGUA_ALBFT Guanylate kinase OS=Albidiferax ferrireducens
(strain ATCC BAA-621 / DSM 15236 / T118) OX=338969 GN=gmk
PE=3 SV=1
Length=206
Score = 233 bits (594), Expect = 2e-71, Method: Composition-based stats.
Identities = 51/185 (28%), Positives = 86/185 (46%), Gaps = 3/185 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
++ P G++ L + L+ + +V HTTR+ R QE GR+Y FVS Q F+A
Sbjct 5 GNLFVVAAPSGAGKSSLVKALL-ELDSHVQLSVSHTTRAPRGQEKHGREYFFVSEQEFDA 63
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+ A F+E ++ YGTS ++ + + G +L + Q ++ IFI
Sbjct 64 MVKADAFVEWASVHQHRYGTSKRAIEERMAQGADVVLEIDYQGALQIKKLFANAISIFIL 123
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS + LRA L + G++ + +E H FD I+N D+A +L +
Sbjct 124 PPSWDELRARLERRGEDSADVIELRLKNAA--IEVAQVHKFDFVIINELFDRALFDLKAI 181
Query 659 INKLD 663
++
Sbjct 182 VHSQR 186
>sp|Q3J2A5|KGUA_CERS4 Guanylate kinase OS=Cereibacter sphaeroides
(strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG
2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) OX=272943 GN=gmk
PE=3 SV=1
Length=211
Score = 233 bits (594), Expect = 2e-71, Method: Composition-based stats.
Identities = 56/190 (29%), Positives = 89/190 (47%), Gaps = 5/190 (3%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A R +IL P G++ L +RL + +V TTR+ R EV GRDY+F +R
Sbjct 2 ARRGLLLILSSPSGAGKSTLSKRLTAWDPS-IRFSVSATTRAPRPGEVDGRDYYFRTRDE 60
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL--KPY 593
F A + AG+ +EH E N YG+ V + + G L + Q + +RNS L
Sbjct 61 FIAAVEAGEMLEHAEVFGNFYGSPKAPVEKALEQGHDTLFDIDWQGGQQIRNSSLGRDVV 120
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+ PPS L L ++ + + + E ++ +D +VN DLD A +
Sbjct 121 SIFVLPPSIGELDRRLRSRAQDSEEVIATRM--ARSKDEISHWAEYDYVLVNRDLDLAEE 178
Query 654 ELLRLINKLD 663
+L +++
Sbjct 179 QLKMILSAER 188
>sp|Q48Q15|KGUA_PSE14 Guanylate kinase OS=Pseudomonas savastanoi
pv. phaseolicola (strain 1448A / Race 6) OX=264730 GN=gmk
PE=3 SV=2
Length=214
Score = 233 bits (594), Expect = 3e-71, Method: Composition-based stats.
Identities = 55/196 (28%), Positives = 91/196 (46%), Gaps = 9/196 (5%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKD-------RFASAVPHTTRSRRDQEVAGRDYHFV 531
I+ P G+ L + LM+ +++ + +V HTTR+ R EV G +Y+FV
Sbjct 6 GTLYIISAPSGAGKTSLVKALMDAQQEPQHGAQAKIRVSVSHTTRAMRPGEVNGVNYNFV 65
Query 532 SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK 591
R F I G F+E E NLYGTS ++Q ++ G +L + Q + +R +
Sbjct 66 DRAEFVRMIEHGDFLEQAEVFGNLYGTSQSHLQQTLDEGHDLILEIDWQGARQVRAQMPQ 125
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
IFI PP+Q+ LR L G++ + E EM ++ + ++ +VN D A
Sbjct 126 ARSIFILPPTQQALRQRLTNRGQDSDEIIEARMREAVSEM--SHYNEYEYVVVNDDFAGA 183
Query 652 YQELLRLINKLDTEPQ 667
++L + Q
Sbjct 184 LEDLKAIFRANRLTQQ 199
>sp|Q0I868|KGUA_SYNS3 Guanylate kinase OS=Synechococcus sp. (strain
CC9311) OX=64471 GN=gmk PE=3 SV=1
Length=190
Score = 232 bits (591), Expect = 3e-71, Method: Composition-based stats.
Identities = 57/181 (31%), Positives = 87/181 (48%), Gaps = 3/181 (2%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
RP +L GP G+ L RL + + + +V TTR+ R E+ G Y F S++ F
Sbjct 9 RPTVLTGPSGVGKGTLVARLRERHPEIW-LSVSATTRAPRSGEIDGIHYFFHSKERFNKL 67
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
+ +G +E EF N YGT + V + + +G LL + + + +R S + IF+AP
Sbjct 68 VQSGGLLEWAEFAGNCYGTPREPVSERVANGIPVLLEIELEGARQVRKSLPEAIQIFLAP 127
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
PS E L + G + R + E+E FD IVN DL+ A EL + +
Sbjct 128 PSVEELEKRIRGRGTEAEEAIQRRLKRAQEELEAQT--EFDAVIVNDDLETALAELEKQM 185
Query 660 N 660
N
Sbjct 186 N 186
>sp|Q5ZTZ8|KGUA_LEGPH Guanylate kinase OS=Legionella pneumophila
subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 /
DSM 7513) OX=272624 GN=gmk PE=3 SV=1
Length=209
Score = 233 bits (593), Expect = 3e-71, Method: Composition-based stats.
Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 5/193 (3%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N I+ P G+ L ++L+ + +V HTTR R E G DY F+ + F
Sbjct 5 NSGNLYIVAAPSGGGKTSLVKKLI-EMVGEIEVSVSHTTRPMRPGEKEGVDYFFIDEKQF 63
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ + G FIEH + + YGTS+ + + + G +L + Q + +R++ +F
Sbjct 64 ISMVNEGAFIEHAKVFNHWYGTSVAQINKRLQFGIDVVLDIDWQGAEQIRHAYPDAVSVF 123
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS + L+ L ++ + + E+ + FD IVN D +KA EL
Sbjct 124 IIPPSLDALKERLMNRRQDKDHVISERMTKAQDEL--GHYPEFDYLIVNDDFEKAAMELQ 181
Query 657 RLI--NKLDTEPQ 667
++ N+L E Q
Sbjct 182 SIVIANRLRIEKQ 194
>sp|Q1G9H8|KGUA_LACDA Guanylate kinase OS=Lactobacillus delbrueckii
subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / BCRC
10696 / JCM 1002 / NBRC 13953 / NCIMB 11778 / NCTC 12712 /
WDCM 00102 / Lb 14) OX=390333 GN=gmk PE=3 SV=1
Length=204
Score = 232 bits (592), Expect = 5e-71, Method: Composition-based stats.
Identities = 51/185 (28%), Positives = 94/185 (51%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A++ ++L GP G+ ++ ++ + F +V TTR R+ EV G+DY+FV+R+
Sbjct 2 ADKGLLLVLSGPSGVGKGTVKSAIVEHKVFPFEYSVSMTTRKPREGEVNGKDYYFVTREE 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F+ IA + +E+ E+ NLYGT + V++++ +GK LL + +T+R + I
Sbjct 62 FKQAIADNQLLEYNEYVGNLYGTPLGPVKEMLAAGKDVLLEIDVNGARTVRQQMPEGVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP LR L G + I + +E+ +D A+VN + A +
Sbjct 122 FLTPPDLHTLRDRLEHRGTESEDVIRGRIAQARKEI--LVMQDYDYAVVNDTVANAVNHI 179
Query 656 LRLIN 660
+++
Sbjct 180 KAIVD 184
>sp|Q83EL7|KGUA_COXBU Guanylate kinase OS=Coxiella burnetii (strain
RSA 493 / Nine Mile phase I) OX=227377 GN=gmk PE=1 SV=1
Length=206
Score = 232 bits (591), Expect = 5e-71, Method: Composition-based stats.
Identities = 53/189 (28%), Positives = 87/189 (46%), Gaps = 3/189 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N+ I+ P G+ L + L+ + ++ HTTR +R + G DY F+ F
Sbjct 2 NKANLFIISAPSGAGKTSLVRALVKALAE-IKISISHTTRPKRPGDQEGVDYFFIDETRF 60
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+A + G F+EH + YGT D V + + +G+ LL + Q + +R IF
Sbjct 61 QAMVKEGAFLEHATIYERHYGTEKDWVLRQLKAGRDVLLEIDWQGARQIRELFPPALSIF 120
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
I PPS E LR L K ++ + + EM + FD +VN + D+A Q L+
Sbjct 121 ILPPSIEALRERLIKRRQDDTAIIEQRLALAREEM--AHYKEFDYLVVNDNFDQAVQNLI 178
Query 657 RLINKLDTE 665
+I+ +
Sbjct 179 HIISAERLQ 187
>sp|P72648|KGUA_SYNY3 Guanylate kinase OS=Synechocystis sp. (strain
PCC 6803 / Kazusa) OX=1111708 GN=gmk PE=3 SV=1
Length=191
Score = 231 bits (590), Expect = 6e-71, Method: Composition-based stats.
Identities = 57/190 (30%), Positives = 94/190 (49%), Gaps = 3/190 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
Q + + + I+L GP G+ L Q L+ ++ F ++ TTRS R EV G+ Y+F+++
Sbjct 5 QTSVKGQLIVLTGPSGVGKGTLVQLLLERQPHWF-LSISATTRSPRAGEVDGQSYYFLTK 63
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ F+ I K +E E+ N YGT V + I GK LL + + ++ +
Sbjct 64 EEFQTWIGEEKLLEWAEYAGNYYGTPRQPVEEQIAQGKTVLLEIEVLGARQIKQTFPSAR 123
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI PPS E L L G + + + + + +E FD +VN DLD+A
Sbjct 124 RIFILPPSVEVLEERLRGRGSDSETAIAKRLAQAQQE--LQAAAEFDYQVVNDDLDQALH 181
Query 654 ELLRLINKLD 663
L++LI + +
Sbjct 182 RLVKLIGEEE 191
>sp|Q4ZZY8|KGUA_PSEU2 Guanylate kinase OS=Pseudomonas syringae
pv. syringae (strain B728a) OX=205918 GN=gmk PE=3 SV=1
Length=214
Score = 232 bits (592), Expect = 6e-71, Method: Composition-based stats.
Identities = 55/196 (28%), Positives = 91/196 (46%), Gaps = 9/196 (5%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKD-------RFASAVPHTTRSRRDQEVAGRDYHFV 531
I+ P G+ L + LM+ +++ + +V HTTR+ R EV G +Y+FV
Sbjct 6 GTLYIISAPSGAGKTSLVKALMDAQQEPQHGAQAKIRVSVSHTTRAMRPGEVDGVNYNFV 65
Query 532 SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK 591
R F + I G F+E E NLYGTS ++Q ++ G +L + Q + +R +
Sbjct 66 DRATFLSMIEHGDFLEQAEVFGNLYGTSQSHLQQTLDEGHDLILEIDWQGARQVRAQMPQ 125
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
IFI PP+Q+ LR L G++ + E EM ++ ++ +VN D A
Sbjct 126 ARSIFILPPTQQALRQRLTNRGQDSDEIIEARMREAVSEM--SHYSEYEYVVVNDDFAGA 183
Query 652 YQELLRLINKLDTEPQ 667
++L + Q
Sbjct 184 LEDLKAIFRANRLTQQ 199
>sp|Q97ID0|KGUA_CLOAB Guanylate kinase OS=Clostridium acetobutylicum
(strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM
B-1787) OX=272562 GN=gmk PE=3 SV=1
Length=209
Score = 232 bits (591), Expect = 6e-71, Method: Composition-based stats.
Identities = 48/184 (26%), Positives = 94/184 (51%), Gaps = 4/184 (2%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ + I++ GP G+ + + LM ++ +F +V TTR R++EV G+ Y+F++
Sbjct 2 SKKGLLIVISGPSGAGKGTICKALMKEQ--QFWLSVSATTREPREKEVEGKSYYFLTVDE 59
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F++ I+ F+E+ E N YGT SV + I++G+ +L + Q ++ + + I
Sbjct 60 FKSKISEDGFLEYAEVYGNYYGTPKKSVCEKIDNGENVILEIDIQGALKVKENYPEGVFI 119
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS E L+ + G + + +E+ N ++ AI+N ++ A ++
Sbjct 120 FILPPSMEELKKRIIGRGSETEKSLMTRFKSAYKEI--NYVSKYNYAIINDTVENAVTKI 177
Query 656 LRLI 659
+I
Sbjct 178 NSII 181
>sp|Q2W9C3|KGUA_MAGSA Guanylate kinase OS=Magnetospirillum magneticum
(strain AMB-1 / ATCC 700264) OX=342108 GN=gmk PE=3 SV=1
Length=214
Score = 232 bits (591), Expect = 8e-71, Method: Composition-based stats.
Identities = 50/195 (26%), Positives = 93/195 (48%), Gaps = 6/195 (3%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R +++ P G+ + + L+ ++ +V TTR+ R EV G+DYHFV+ +
Sbjct 9 SRRGLMLVMSSPSGAGKTTISRALLERDP-AIGMSVSATTRAPRPGEVDGKDYHFVTVEK 67
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTL-RNSDLKPYI 594
F + +F+EH N YGT V +++ SG+ L + Q + + +N+
Sbjct 68 FHEMVEKREFLEHARVFDNFYGTPRGPVDEILRSGRDVLFDIDWQGTQQMAQNARADLVS 127
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
+F+ PPS E L L ++ + + + EM ++ +D +VN DLDK+
Sbjct 128 VFVLPPSVEELERRLRGRAQDSDEVVRKRMAKAGDEM--SHWPEYDYIVVNIDLDKSIAA 185
Query 655 LLRLI--NKLDTEPQ 667
+ ++ +L E Q
Sbjct 186 VQAILAAERLKRERQ 200
>sp|Q1LTY3|KGUA_BAUCH Guanylate kinase OS=Baumannia cicadellinicola
subsp. Homalodisca coagulata OX=374463 GN=gmk PE=3 SV=1
Length=204
Score = 231 bits (589), Expect = 1e-70, Method: Composition-based stats.
Identities = 49/182 (27%), Positives = 83/182 (46%), Gaps = 5/182 (3%)
Query 481 PIILIGPQNCGQNELRQRLMNKEK---DRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
I+ P G++ L Q L+ ++ ++ HTTR+ R E+ G+ Y+F+S + FE
Sbjct 2 LYIISAPSGTGKSSLLQALLRTKRLPLHEIRISISHTTRAMRPGEINGQHYYFISVEEFE 61
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I F+E+ + YGT V ++ + LL + Q K + IFI
Sbjct 62 KLIDQDAFLEYARVFNHYYGTLRQEVDSILINSVDILLDIDWQGAKQIYAIRKDVRSIFI 121
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS++ L L K G++ + + I + EM + +D I+N D A +L
Sbjct 122 IPPSKDELHRRLHKRGQDQEEVINQRISQAVAEM--IHYTEYDYLIINDDFHTALSDLNT 179
Query 658 LI 659
+I
Sbjct 180 II 181
>sp|Q1MRL0|KGUA_LAWIP Guanylate kinase OS=Lawsonia intracellularis
(strain PHE/MN1-00) OX=363253 GN=gmk PE=3 SV=1
Length=212
Score = 231 bits (589), Expect = 2e-70, Method: Composition-based stats.
Identities = 57/188 (30%), Positives = 90/188 (48%), Gaps = 5/188 (3%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ P G+ L QRL + FA ++ TTR R E G+DY+F+S++ F A
Sbjct 17 LVICAPSGTGKTTLIQRLRKEFP-CFAYSISCTTRPPRKNEEDGKDYYFISQEEFIARKN 75
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
F E YGT + + ++N+G+ L + Q L + IF+ PP+
Sbjct 76 EKYFAEWAYVHGYFYGTPLAPILTILNNGQDILFDIDVQGAAQLYLTLPYAKYIFLLPPT 135
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR--LI 659
L L G + + ++ T+E+ Q H+FDT IVN ++DKAY EL L
Sbjct 136 MVELEKRLRSRGTDREDIIQHRLLSATQEIRQ--AHWFDTWIVNENIDKAYDELRATYLA 193
Query 660 NKLDTEPQ 667
+KL + Q
Sbjct 194 SKLSPKFQ 201
>sp|Q5WFK3|KGUA_SHOC1 Guanylate kinase OS=Shouchella clausii (strain
KSM-K16) OX=66692 GN=gmk PE=3 SV=1
Length=205
Score = 231 bits (588), Expect = 2e-70, Method: Composition-based stats.
Identities = 51/186 (27%), Positives = 86/186 (46%), Gaps = 3/186 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ I+L GP G+ + L N+ +V TTR R+ E G +Y F +R
Sbjct 1 MKREKGLLIVLSGPAGVGKGTVCGALRNQN-TAIEYSVSATTRKPREGEKHGVNYFFKTR 59
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ FE I GK +E E+ N YGT ID V++ IN+GK +L + Q + +R +
Sbjct 60 EQFEQMIEDGKLLEWAEYVGNYYGTPIDYVQETINAGKDIILEIEVQGAQKVRTVFPEGV 119
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+APPS + LR + G + + E++ +D + N ++ A +
Sbjct 120 FIFLAPPSLKELRDRIVGRGTETEDIINERMTVAKEEIDLMTM--YDYVVENDKVEWAVE 177
Query 654 ELLRLI 659
+ ++
Sbjct 178 RIKAIV 183
>sp|Q89MV4|KGUA_BRADU Guanylate kinase OS=Bradyrhizobium diazoefficiens
(strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC
14792 / USDA 110) OX=224911 GN=gmk PE=3 SV=1
Length=219
Score = 231 bits (589), Expect = 2e-70, Method: Composition-based stats.
Identities = 48/188 (26%), Positives = 82/188 (44%), Gaps = 4/188 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R +L P G+ L + L+ + +V TTR R EV GRDY FV + F
Sbjct 13 RRGLMFVLSSPSGAGKTTLSRLLIERMPG-LRMSVSATTRPMRPGEVDGRDYLFVDKPRF 71
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLR-NSDLKPYII 595
EA + + +E N YGT V +++G+ L + Q + LR + +
Sbjct 72 EAMVRDDELLEWATVFDNRYGTPRAPVEAALSAGQDVLFDIDWQGTQQLREKARADVVSV 131
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS L L ++ + + + EM ++ +D ++N D+D+A+ E+
Sbjct 132 FILPPSAGDLEKRLHSRAQDSDEVIRKRMSRASHEM--SHWAEYDYIVINHDVDEAFAEV 189
Query 656 LRLINKLD 663
++
Sbjct 190 QSILKAER 197
>sp|P65218|KGUA_BRUSU Guanylate kinase OS=Brucella suis biovar
1 (strain 1330) OX=204722 GN=gmk PE=3 SV=1
Length=220
Score = 231 bits (589), Expect = 2e-70, Method: Composition-based stats.
Identities = 45/189 (24%), Positives = 84/189 (44%), Gaps = 3/189 (2%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A R +++ P G++ + + L+ K + + ++ TTR RR E+ G YHF++ +
Sbjct 11 ARRGLMVVISSPSGAGKSTIARLLLEDPKMKLSLSISVTTRQRRPSEIDGVHYHFITIRE 70
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL-KPYI 594
FE + IE E N YGT ++ + G+ L + Q L+
Sbjct 71 FERLRDNDELIEWAEVHGNFYGTLRETAEIALADGQDMLFDIDWQGADQLQAKMPADVVS 130
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFI PP+ L+ L + ++ + E+++ +D ++N DLD++Y
Sbjct 131 IFILPPTMRELQQRLNRRAEDTAEVIETRLQNARFEIQK--WVKYDYIVINEDLDRSYAA 188
Query 655 LLRLINKLD 663
+ +IN
Sbjct 189 IKSIINAER 197
>sp|P65217|KGUA_BRUME Guanylate kinase OS=Brucella melitensis
biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) OX=224914 GN=gmk
PE=3 SV=1
Length=220
Score = 231 bits (589), Expect = 2e-70, Method: Composition-based stats.
Identities = 45/189 (24%), Positives = 84/189 (44%), Gaps = 3/189 (2%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A R +++ P G++ + + L+ K + + ++ TTR RR E+ G YHF++ +
Sbjct 11 ARRGLMVVISSPSGAGKSTIARLLLEDPKMKLSLSISVTTRQRRPSEIDGVHYHFITIRE 70
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL-KPYI 594
FE + IE E N YGT ++ + G+ L + Q L+
Sbjct 71 FERLRDNDELIEWAEVHGNFYGTLRETAEIALADGQDMLFDIDWQGADQLQAKMPADVVS 130
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFI PP+ L+ L + ++ + E+++ +D ++N DLD++Y
Sbjct 131 IFILPPTMRELQQRLNRRAEDTAEVIETRLQNARFEIQK--WVKYDYIVINEDLDRSYAA 188
Query 655 LLRLINKLD 663
+ +IN
Sbjct 189 IKSIINAER 197
>sp|Q57EQ3|KGUA_BRUAB Guanylate kinase OS=Brucella abortus biovar
1 (strain 9-941) OX=262698 GN=gmk PE=3 SV=1
Length=220
Score = 231 bits (589), Expect = 2e-70, Method: Composition-based stats.
Identities = 45/189 (24%), Positives = 84/189 (44%), Gaps = 3/189 (2%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A R +++ P G++ + + L+ K + + ++ TTR RR E+ G YHF++ +
Sbjct 11 ARRGLMVVISSPSGAGKSTIARLLLEDPKMKLSLSISVTTRQRRPSEIDGVHYHFITIRE 70
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL-KPYI 594
FE + IE E N YGT ++ + G+ L + Q L+
Sbjct 71 FERLRDNDELIEWAEVHGNFYGTLRETAEIALADGQDMLFDIDWQGADQLQAKMPADVVS 130
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFI PP+ L+ L + ++ + E+++ +D ++N DLD++Y
Sbjct 131 IFILPPTMRELQQRLNRRAEDTAEVIETRLQNARFEIQK--WVKYDYIVINEDLDRSYAA 188
Query 655 LLRLINKLD 663
+ +IN
Sbjct 189 IKSIINAER 197
>sp|Q2YMJ2|KGUA_BRUA2 Guanylate kinase OS=Brucella abortus (strain
2308) OX=359391 GN=gmk PE=3 SV=1
Length=220
Score = 231 bits (589), Expect = 2e-70, Method: Composition-based stats.
Identities = 45/189 (24%), Positives = 84/189 (44%), Gaps = 3/189 (2%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A R +++ P G++ + + L+ K + + ++ TTR RR E+ G YHF++ +
Sbjct 11 ARRGLMVVISSPSGAGKSTIARLLLEDPKMKLSLSISVTTRQRRPSEIDGVHYHFITIRE 70
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL-KPYI 594
FE + IE E N YGT ++ + G+ L + Q L+
Sbjct 71 FERLRDNDELIEWAEVHGNFYGTLRETAEIALADGQDMLFDIDWQGADQLQAKMPADVVS 130
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFI PP+ L+ L + ++ + E+++ +D ++N DLD++Y
Sbjct 131 IFILPPTMRELQQRLNRRAEDTAEVIETRLQNARFEIQK--WVKYDYIVINEDLDRSYAA 188
Query 655 LLRLINKLD 663
+ +IN
Sbjct 189 IKSIINAER 197
>sp|Q92GC9|KGUA_RICCN Guanylate kinase OS=Rickettsia conorii (strain
ATCC VR-613 / Malish 7) OX=272944 GN=gmk PE=3 SV=1
Length=229
Score = 231 bits (589), Expect = 3e-70, Method: Composition-based stats.
Identities = 45/192 (23%), Positives = 88/192 (46%), Gaps = 5/192 (3%)
Query 468 EMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRD 527
E+ L ++ IIL P G++ L + L+ + + ++ TTR R EV G +
Sbjct 35 EVELSR--NSKGLIIILSSPSGTGKSSLAKALLKID-NNLRLSISATTRKPRLGEVEGIN 91
Query 528 YHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN 587
Y+F + FE + KF+E+ + N YGT + V ++N G L + Q ++++
Sbjct 92 YYFKTGLEFEELVKQNKFLEYAKIYDNYYGTPKEYVEMLLNQGLDVLFDIDWQGARSIKK 151
Query 588 SDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD 647
+ IF+ PP+ E L L + + + E+ ++ + +D + N D
Sbjct 152 NATNVVTIFVLPPNIEVLEQRLRNRATDNEEAIKLRMQLAQNEI--SHANEYDYVVTNDD 209
Query 648 LDKAYQELLRLI 659
D+ +++ +I
Sbjct 210 FDRTLKKIHAII 221
>sp|Q54XF2|KGUA_DICDI Guanylate kinase OS=Dictyostelium discoideum
OX=44689 GN=guk1 PE=3 SV=1
Length=202
Score = 229 bits (585), Expect = 4e-70, Method: Composition-based stats.
Identities = 60/181 (33%), Positives = 93/181 (51%), Gaps = 1/181 (1%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
PII+ GP G+ L +L + + F V HTTR R+ E+ G YHF I
Sbjct 11 PIIITGPSGVGKGTLIDKLRKEYEGSFGHIVSHTTRKPREGEINGVHYHFTDIPTMTEGI 70
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
G FIEH N YGTS +++ V + KIC+L + Q ++++ +++ IFI+PP
Sbjct 71 KNGDFIEHANVHGNFYGTSKKALKDVSDKNKICILDIDVQGCESVKKANIPCKFIFISPP 130
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREME-QNNGHYFDTAIVNSDLDKAYQELLRLI 659
+ E L+ L G + + + +EM ++ +FD IVN+ LD AY EL +I
Sbjct 131 TFETLQERLIGRGTENEETLKKRLETAKKEMVYRDIPGFFDHVIVNNVLDVAYGELKSII 190
Query 660 N 660
+
Sbjct 191 S 191
>sp|Q12DV7|KGUA_POLSJ Guanylate kinase OS=Polaromonas sp. (strain
JS666 / ATCC BAA-500) OX=296591 GN=gmk PE=3 SV=1
Length=206
Score = 230 bits (586), Expect = 4e-70, Method: Composition-based stats.
Identities = 51/185 (28%), Positives = 85/185 (46%), Gaps = 3/185 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
++ P G++ L + LM + AV HTTR R QE GR+Y F+S + F++
Sbjct 5 GNLFVVAAPSGAGKSSLVKALM-ELDSAIQPAVSHTTRPPRGQEKHGREYFFLSPEEFDS 63
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+ F+E + YGTS ++ + I GK +L + Q ++ +IFI
Sbjct 64 MVQRDAFLEWAHVHGHRYGTSRQAIEERIAHGKDVILEIDFQGAINIKRIFSNAVLIFIL 123
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS E LR+ L + G++ + EM Q FD I+N ++A +L +
Sbjct 124 PPSWEELRSRLQRRGEDSPEVIELRLKNAATEMAQ--AREFDFVIINELFERAVFDLKTI 181
Query 659 INKLD 663
++
Sbjct 182 VHAQR 186
>sp|Q2NIH1|KGUA_AYWBP Guanylate kinase OS=Aster yellows witches'-broom
phytoplasma (strain AYWB) OX=322098 GN=gmk PE=3 SV=1
Length=211
Score = 229 bits (585), Expect = 5e-70, Method: Composition-based stats.
Identities = 50/184 (27%), Positives = 82/184 (45%), Gaps = 3/184 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ IIL GP G+ +R+ L F +V TTR R E G+DYHF++++ FE
Sbjct 6 KGLLIILSGPSGVGKATVRKALFEMTNHNFVYSVSATTRKPRPGEQDGKDYHFLTKEEFE 65
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS-DLKPYIIF 596
I F+E +F + YGT ++ + GK L + + LR IF
Sbjct 66 KGIENNCFLEWAKFIDHYYGTPKKQIQDFLKQGKEVFLEIEVEGATHLRKKRMPNTVFIF 125
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+ PP ++ L L K G + ++ I + E H +D +VN ++ A ++
Sbjct 126 LVPPKKKDLYDRLKKRGTEQEINIVQRIAKANNEFRL--AHKYDYIVVNDEVANAADRII 183
Query 657 RLIN 660
+I
Sbjct 184 AIIR 187
>sp|P60554|KGUA_ONYPE Guanylate kinase OS=Onion yellows phytoplasma
(strain OY-M) OX=262768 GN=gmk PE=3 SV=1
Length=212
Score = 229 bits (584), Expect = 7e-70, Method: Composition-based stats.
Identities = 49/184 (27%), Positives = 82/184 (45%), Gaps = 3/184 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ I+L GP G+ +R+ L F +V TTR R E G+DYHF++++ FE
Sbjct 6 KGLLIVLSGPSGVGKATVRKALFEMTNHNFVYSVSATTRKPRPGEQDGKDYHFLTKEEFE 65
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD-LKPYIIF 596
I F+E +F + YGT ++ + GK L + + LR IF
Sbjct 66 KGIENNCFLEWAKFIDHYYGTPKKQIQDFLKQGKEVFLEIEVEGATHLRKKRIPNTVFIF 125
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+ PP ++ L L K G + + I + E + H +D +VN ++ A ++
Sbjct 126 LVPPEKKALYDRLKKRGTEQEANIAKRIAKANNEF--HLAHKYDYIVVNDEVANAADRII 183
Query 657 RLIN 660
+I
Sbjct 184 AIIR 187
>sp|Q1GH67|KGUA_RUEST Guanylate kinase OS=Ruegeria sp. (strain
TM1040) OX=292414 GN=gmk PE=3 SV=1
Length=217
Score = 229 bits (584), Expect = 9e-70, Method: Composition-based stats.
Identities = 62/197 (31%), Positives = 95/197 (48%), Gaps = 5/197 (3%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R IIL P G++ L +RL + D + +V TTR R EV G+DYHFV+ ++F
Sbjct 8 RRGLLIILSSPSGAGKSTLAKRLRAWDSD-ISFSVSATTRKPRPGEVDGQDYHFVTVESF 66
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL--KPYI 594
+ D+A G +EH N YG+ V+ IN G+ L + Q + + NSDL
Sbjct 67 KQDVANGDMLEHAHVFGNFYGSPKGPVQTAINEGRDVLFDIDWQGAQQITNSDLGKHTLS 126
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IF+ PPS LR L G++ R + + E+ ++ +D ++N DLD+ +
Sbjct 127 IFLLPPSITELRRRLESRGQDDAETISRRMQKSWDEI--SHWGSYDHVLINEDLDETEEA 184
Query 655 LLRLINKLDTEPQWVPS 671
L +I PS
Sbjct 185 LKTIITATRLRRIQQPS 201
>sp|Q827Q3|KGUA_STRAW Guanylate kinase OS=Streptomyces avermitilis
(strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893
/ NCIMB 12804 / NRRL 8165 / MA-4680) OX=227882 GN=gmk PE=3 SV=1
Length=197
Score = 228 bits (582), Expect = 9e-70, Method: Composition-based stats.
Identities = 55/186 (30%), Positives = 88/186 (47%), Gaps = 3/186 (2%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
P R R +L GP G++ + + + + + +V TTR R E G Y FVS
Sbjct 13 PDARPRLTVLSGPSGVGKSTVVAHMRKEHPEVW-LSVSATTRKPRPGEKHGVHYFFVSDD 71
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
+ IA G+ +E EF N YGT +V + + G+ LL + Q + +R S + +
Sbjct 72 EMDKLIANGELLEWAEFAGNRYGTPRQAVLERLERGEPVLLEIDLQGARQVRESMPEALL 131
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
+F+APPS E L L G P R + ++E FD +VN+ ++ +E
Sbjct 132 VFLAPPSWEELVRRLTGRGTEPPEVIERRL--DAAKVELAAEPEFDVTLVNTSVEDVARE 189
Query 655 LLRLIN 660
LL L++
Sbjct 190 LLALVD 195
>sp|Q68VY3|KGUA_RICTY Guanylate kinase OS=Rickettsia typhi (strain
ATCC VR-144 / Wilmington) OX=257363 GN=gmk PE=3 SV=1
Length=197
Score = 228 bits (582), Expect = 9e-70, Method: Composition-based stats.
Identities = 40/183 (22%), Positives = 88/183 (48%), Gaps = 3/183 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
++ IIL P G++ L + L+ + + ++ TTR R EV G +Y+F + F
Sbjct 5 HKGLIIILSSPSGTGKSSLAKELLKID-NNLRLSISVTTRKPRLGEVDGINYYFKTDLEF 63
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ + KF+E+ + + YGT + V+ ++ G L + Q +++++ + IF
Sbjct 64 KTLVKQNKFLEYAKIYNDYYGTPKEYVKMLLKQGLDVLFDIDWQGVRSIKKNTNNVVTIF 123
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+ PPS E L L + + ++ ++ + E + + +D ++N D + +++
Sbjct 124 VLPPSLEILEQRLRNRATDNEETI--KLRMQSAQHEISYANEYDYVVINDDFGQTLKKIH 181
Query 657 RLI 659
+I
Sbjct 182 EII 184
>sp|Q6HEU4|KGUA_BACHK Guanylate kinase OS=Bacillus thuringiensis
subsp. konkukian (strain 97-27) OX=281309 GN=gmk PE=3 SV=2
Length=205
Score = 229 bits (583), Expect = 1e-69, Method: Composition-based stats.
Identities = 52/186 (28%), Positives = 86/186 (46%), Gaps = 2/186 (1%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ R I+L GP G+ +R+ L + E RF ++ TTR R+ EV G DY F R
Sbjct 1 MRSRRGLLIVLSGPSGVGKGTVRKELFSHEDTRFQYSISVTTRKPREGEVDGVDYFFKER 60
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ FE I K +E EF N YGT ID V + + GK L + Q ++ + +
Sbjct 61 EEFEEMIRNEKLLEWAEFVGNYYGTPIDYVEKTLQEGKDVFLEIEVQGAIQVKKAFPEGV 120
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+APPS L+ + G + + E++ + +D + N ++ A +
Sbjct 121 FIFLAPPSLSELKNRIVGRGTETEDVIENRLTVAKEEIDMMDA--YDYVVENDQVELACE 178
Query 654 ELLRLI 659
+ ++
Sbjct 179 RIKAIV 184
>sp|Q636F5|KGUA_BACCZ Guanylate kinase OS=Bacillus cereus (strain
ZK / E33L) OX=288681 GN=gmk PE=3 SV=2
Length=205
Score = 229 bits (583), Expect = 1e-69, Method: Composition-based stats.
Identities = 52/186 (28%), Positives = 86/186 (46%), Gaps = 2/186 (1%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ R I+L GP G+ +R+ L + E RF ++ TTR R+ EV G DY F R
Sbjct 1 MRSRRGLLIVLSGPSGVGKGTVRKELFSHEDTRFQYSISVTTRKPREGEVDGVDYFFKER 60
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ FE I K +E EF N YGT ID V + + GK L + Q ++ + +
Sbjct 61 EEFEEMIRNEKLLEWAEFVGNYYGTPIDYVEKTLQEGKDVFLEIEVQGAIQVKKAFPEGV 120
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+APPS L+ + G + + E++ + +D + N ++ A +
Sbjct 121 FIFLAPPSLSELKNRIVGRGTETEDVIENRLTVAKEEIDMMDA--YDYVVENDQVELACE 178
Query 654 ELLRLI 659
+ ++
Sbjct 179 RIKAIV 184
>sp|Q732K0|KGUA_BACC1 Guanylate kinase OS=Bacillus cereus (strain
ATCC 10987 / NRS 248) OX=222523 GN=gmk PE=3 SV=2
Length=205
Score = 229 bits (583), Expect = 1e-69, Method: Composition-based stats.
Identities = 52/186 (28%), Positives = 86/186 (46%), Gaps = 2/186 (1%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ R I+L GP G+ +R+ L + E RF ++ TTR R+ EV G DY F R
Sbjct 1 MRSRRGLLIVLSGPSGVGKGTVRKELFSHEDTRFQYSISVTTRKPREGEVDGVDYFFKER 60
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ FE I K +E EF N YGT ID V + + GK L + Q ++ + +
Sbjct 61 EEFEEMIRNEKLLEWAEFVGNYYGTPIDYVEKTLQEGKDVFLEIEVQGAIQVKKAFPEGV 120
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+APPS L+ + G + + E++ + +D + N ++ A +
Sbjct 121 FIFLAPPSLSELKNRIVGRGTETEDVIENRLTVAKEEIDMMDA--YDYVVENDQVELACE 178
Query 654 ELLRLI 659
+ ++
Sbjct 179 RIKAIV 184
>sp|Q81WG7|KGUA_BACAN Guanylate kinase OS=Bacillus anthracis OX=1392
GN=gmk PE=3 SV=1
Length=205
Score = 229 bits (583), Expect = 1e-69, Method: Composition-based stats.
Identities = 52/186 (28%), Positives = 86/186 (46%), Gaps = 2/186 (1%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ R I+L GP G+ +R+ L + E RF ++ TTR R+ EV G DY F R
Sbjct 1 MRSRRGLLIVLSGPSGVGKGTVRKELFSHEDTRFQYSISVTTRKPREGEVDGVDYFFKER 60
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ FE I K +E EF N YGT ID V + + GK L + Q ++ + +
Sbjct 61 EEFEEMIRNEKLLEWAEFVGNYYGTPIDYVEKTLQEGKDVFLEIEVQGAIQVKKAFPEGV 120
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+APPS L+ + G + + E++ + +D + N ++ A +
Sbjct 121 FIFLAPPSLSELKNRIVGRGTETEDVIENRLTVAKEEIDMMDA--YDYVVENDQVELACE 178
Query 654 ELLRLI 659
+ ++
Sbjct 179 RIKAIV 184
>sp|Q82SQ3|KGUA_NITEU Guanylate kinase OS=Nitrosomonas europaea
(strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)
OX=228410 GN=gmk PE=3 SV=1
Length=201
Score = 228 bits (582), Expect = 1e-69, Method: Composition-based stats.
Identities = 51/193 (26%), Positives = 92/193 (48%), Gaps = 5/193 (3%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
++ P G+ + + L+ + + ++ +TTR R E G DY FV F+
Sbjct 4 LFVISAPSGAGKTSVIRTLLQTDIN-LTLSISYTTRPPRRDEKNGHDYFFVDHATFKDMQ 62
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
A G+F+E E NLYGTS + + + + + LL + Q + +R + IFI PP
Sbjct 63 ARGEFLESAEVHGNLYGTSRKWIEETMAAEQDVLLEIDCQGAQQIRTVYPQAASIFILPP 122
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
S E L+ L + G++ R + E+ ++ + FD +VN +L+ A +++ ++
Sbjct 123 SMEALKQRLEQRGQDENKVIERRLAAARSEI--SHVNRFDYVVVNHELETAARDVASIVQ 180
Query 661 --KLDTEPQWVPS 671
+L T Q V
Sbjct 181 AERLKTIRQLVRQ 193
>sp|Q9KXS0|KGUA_STRCO Guanylate kinase OS=Streptomyces coelicolor
(strain ATCC BAA-471 / A3(2) / M145) OX=100226 GN=gmk PE=3
SV=1
Length=197
Score = 228 bits (581), Expect = 1e-69, Method: Composition-based stats.
Identities = 54/184 (29%), Positives = 88/184 (48%), Gaps = 3/184 (2%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
P R R +L GP G++ + + + + + +V TTR R E G Y FVS +
Sbjct 13 PDARPRLTVLSGPSGVGKSTVVAHMRKEHPEVW-LSVSATTRRPRPGEQHGVHYFFVSDE 71
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
+ IA G+ +E EF N YGT +V + + +G+ LL + Q + +R S + +
Sbjct 72 EMDKLIANGELLEWAEFAGNRYGTPRTAVLERLEAGEPVLLEIDLQGARQVRESMPEARL 131
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
+F+APPS + L L G P R + ++E FD +VN+ ++ +E
Sbjct 132 VFLAPPSWDELVRRLTGRGTEPPEVIERRL--AAAKVELAAEPEFDQTLVNTSVEDVARE 189
Query 655 LLRL 658
LL L
Sbjct 190 LLAL 193
>sp|Q47R17|KGUA_THEFY Guanylate kinase OS=Thermobifida fusca (strain
YX) OX=269800 GN=gmk PE=3 SV=1
Length=196
Score = 228 bits (581), Expect = 1e-69, Method: Composition-based stats.
Identities = 53/187 (28%), Positives = 89/187 (48%), Gaps = 3/187 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
KR +L GP G++ + + L + + + +V TTR R E G +Y+FV F+
Sbjct 13 KRLTVLSGPSGVGKSTVVKELRRRRPEVW-LSVSVTTRPPRPGETDGVEYYFVDDAEFDR 71
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+A + +E EF N YGT + V + + +G+ LL + + +R + +++F+A
Sbjct 72 LVAENELLEWAEFAGNRYGTPREPVLKRLAAGQPVLLEIDLNGARQVRANMPDAFLVFLA 131
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS E L L G R + +T +E FD +VN+ + + ELL L
Sbjct 132 PPSWEELVRRLTGRGTESPEVIQRRL--ETARIELAAEKEFDVTLVNTSVHEVCDELLAL 189
Query 659 INKLDTE 665
I T+
Sbjct 190 IAAPSTQ 196
>sp|Q8UGD7|KGUA_AGRFC Guanylate kinase OS=Agrobacterium fabrum
(strain C58 / ATCC 33970) OX=176299 GN=gmk PE=3 SV=1
Length=220
Score = 229 bits (584), Expect = 1e-69, Method: Composition-based stats.
Identities = 47/189 (25%), Positives = 91/189 (48%), Gaps = 4/189 (2%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A R +++ P G++ + + L+ K+K+ + +V TTR RR E+ G YHF+S++
Sbjct 12 ARRGLMLVISSPSGAGKSTIARNLLEKDKN-ISLSVSVTTRPRRQSEIEGIHYHFISKRD 70
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL-KPYI 594
FE + +E E N YGT + V + +G+ L + Q + L++
Sbjct 71 FERMRDGDELLEWAEVHGNFYGTPREPVEAAMAAGRDMLFDIDWQGAEQLQDKMKADVVS 130
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFI PP+ L++ L + ++ + ++ E+E + +D I+N DL A++
Sbjct 131 IFILPPTMTELQSRLHRRAEDSEEVIKTRLLNSRAEIE--HWRDYDYVILNDDLQAAFEG 188
Query 655 LLRLINKLD 663
+ ++
Sbjct 189 IEAIVKAER 197
>sp|Q0AQC4|KGUA_MARMM Guanylate kinase OS=Maricaulis maris (strain
MCS10) OX=394221 GN=gmk PE=3 SV=1
Length=218
Score = 229 bits (583), Expect = 1e-69, Method: Composition-based stats.
Identities = 58/209 (28%), Positives = 97/209 (46%), Gaps = 10/209 (5%)
Query 472 YHQPANRKR----PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRD 527
Y P R R + L P G+ L +RL+++ D +V TTR R EV G+D
Sbjct 6 YPAPIFRGRRRGVLLALSSPSGAGKTTLSKRLLSQNPD-VVLSVSATTRKPRPGEVDGQD 64
Query 528 YHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN 587
YHF+S F+ I +F E E YGT V + + G+ + + Q + L
Sbjct 65 YHFISVDEFKKKIEDDEFFEWAEVFGRYYGTPKTPVMEAVEDGRDVVFDIDWQGAQALAA 124
Query 588 SDLKPYI-IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNS 646
+ + +FI PPS L L K G++ E +++ + + ++ E ++ H +D IVN
Sbjct 125 AAPDDAVRVFILPPSLALLEDRLRKRGQDTT-EIIKDRMARAKD-EISHWHEYDYVIVND 182
Query 647 DLDKAYQELLRLINKLDTEPQWVPSTWLR 675
D +A ++L +++ + P WL
Sbjct 183 DFARALEKLNEILHAERLKRLRHP--WLE 209
>sp|Q110R6|KGUA_TRIEI Guanylate kinase OS=Trichodesmium erythraeum
(strain IMS101) OX=203124 GN=gmk PE=3 SV=1
Length=186
Score = 228 bits (580), Expect = 1e-69, Method: Composition-based stats.
Identities = 51/185 (28%), Positives = 83/185 (45%), Gaps = 3/185 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+ I+L GP G+ L L+++ A +V TTRS R EV G+ Y FV F
Sbjct 4 GKLIVLTGPSGVGKGTLLSCLLHRHPG-LAFSVSVTTRSPRPGEVEGKSYFFVDHDQFRE 62
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
I + + +E E+ N YGT V + I G+ +L + Q + ++ + IFI
Sbjct 63 MIESEELLEWAEYAGNFYGTPRVPVIENIEQGRSMILEIELQGARQIQRTFPDALRIFIL 122
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS L L G++ + + + T E+E FD +VN ++ Q L ++
Sbjct 123 PPSMAELEERLWGRGQDSEEAITKRLQRATEELE--AATEFDIQLVNDSIEDTLQNLDKI 180
Query 659 INKLD 663
+
Sbjct 181 LFHFR 185
>sp|Q2RXB1|KGUA_RHORT Guanylate kinase OS=Rhodospirillum rubrum
(strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB
8255 / S1) OX=269796 GN=gmk PE=3 SV=1
Length=218
Score = 229 bits (583), Expect = 2e-69, Method: Composition-based stats.
Identities = 44/189 (23%), Positives = 74/189 (39%), Gaps = 4/189 (2%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
R ++L P G+ + + L+ +E D +V TTR+ R E G YHF+
Sbjct 12 PRRGMMLVLSSPSGAGKTTISRALLAEE-DGLEMSVSVTTRAPRPGERDGEHYHFIDVAR 70
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTL-RNSDLKPYI 594
+ A +EH +N YGT V + G L + Q + + +
Sbjct 71 YMALTKDDGLLEHARVFENYYGTPRAPVEAALARGCDVLFDIDWQGTQQVAEKARTDLVS 130
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFI PPS L L ++ + + E+ +D IVN DLD++ +
Sbjct 131 IFILPPSVGELERRLKGRAQDSDAVVAARMAKAMDEISHYF--EYDYIIVNDDLDRSIAD 188
Query 655 LLRLINKLD 663
+ ++
Sbjct 189 VRAILRAER 197
>sp|Q5YTM7|KGUA_NOCFA Guanylate kinase OS=Nocardia farcinica (strain
IFM 10152) OX=247156 GN=gmk PE=3 SV=1
Length=193
Score = 228 bits (580), Expect = 2e-69, Method: Composition-based stats.
Identities = 56/186 (30%), Positives = 94/186 (51%), Gaps = 5/186 (3%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R ++L+GP G++ + + + + + +V TTR+ R EV GRDY FV+R
Sbjct 5 TRKGRLVVLVGPSAVGKSTVVRCVRERLPE-LVFSVSATTRAPRPGEVDGRDYRFVTRAE 63
Query 536 FEADIAAGKFIEHGEFEKNLY--GTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
F+A I AG+ +E E L GT VR+ + +GK LL + + +++R +
Sbjct 64 FDAMIEAGELLEWAEIHGGLQRSGTPAAPVREALAAGKNVLLEVDLEGARSVRKVMPEAR 123
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
++F+APPS + L A L G R + +T +E FD IVN ++ A +
Sbjct 124 LVFLAPPSWDELVARLTARGTETPEVIARRL--ETARIELAACDEFDNVIVNDEVTSACE 181
Query 654 ELLRLI 659
+L+ L
Sbjct 182 QLVSLF 187
>sp|Q7VDB6|KGUA_PROMA Guanylate kinase OS=Prochlorococcus marinus
(strain SARG / CCMP1375 / SS120) OX=167539 GN=gmk PE=3 SV=1
Length=184
Score = 226 bits (577), Expect = 4e-69, Method: Composition-based stats.
Identities = 52/186 (28%), Positives = 93/186 (50%), Gaps = 3/186 (2%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
N I++ GP G+ L ++L+ + + + ++ TTR+ R+ E+ G+DY F++++
Sbjct 2 TNYNGLIVITGPSGVGKGTLVKKLLLENPEIW-LSISATTRTPREGEINGKDYFFLNKKE 60
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F + F+E EF N YGT ++ I+ GK LL + + +R + + + I
Sbjct 61 FIDLVDKEGFLEWAEFAGNFYGTPRAQAQEKISVGKKVLLEIELDGARQVRKTFPEGFQI 120
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FIAPPS E L + G + + + + +E E + FD ++N LD A E+
Sbjct 121 FIAPPSFEELEKRIRTRGTDSELAIQSRL-NRAKE-ELLAKNEFDAIVINDQLDIALLEI 178
Query 656 LRLINK 661
+LI
Sbjct 179 KKLIKS 184
>sp|Q5FJH2|KGUA_LACAC Guanylate kinase OS=Lactobacillus acidophilus
(strain ATCC 700396 / NCK56 / N2 / NCFM) OX=272621 GN=gmk
PE=3 SV=1
Length=204
Score = 226 bits (577), Expect = 7e-69, Method: Composition-based stats.
Identities = 46/185 (25%), Positives = 85/185 (46%), Gaps = 2/185 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A++ ++L GP G+ ++ ++ + F +V TTR R EV G+DY+FVS
Sbjct 2 ADKGLLLVLSGPSGVGKGTVKSAIVENKVFPFEYSVSMTTRKPRPGEVNGKDYYFVSEGR 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F+ I G+ +E+ + + YGT + V+++++ GK LL + + +R I
Sbjct 62 FKEAINNGELLEYNNYVGHYYGTPLGPVKEMLHEGKDVLLEIDVNGAQKVREKMPDGVFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PP L L G + I + E+ +D A+VN + A +
Sbjct 122 FLTPPDLHTLHLRLEHRGTESEDVIRGRIKQARNEI--LEMEDYDYAVVNDTVANAVDHI 179
Query 656 LRLIN 660
+++
Sbjct 180 KAIVD 184
>sp|Q87DG5|KGUA_XYLFT Guanylate kinase OS=Xylella fastidiosa (strain
Temecula1 / ATCC 700964) OX=183190 GN=gmk PE=3 SV=1
Length=204
Score = 226 bits (577), Expect = 7e-69, Method: Composition-based stats.
Identities = 47/192 (24%), Positives = 83/192 (43%), Gaps = 5/192 (3%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R I+ G++ + + ++ + A ++ T+R R E + Y+FVS F+
Sbjct 2 RGTLYIVSASSGTGKSSIVNATLERD-QQIALSISFTSRQPRPNERHAQHYYFVSADEFQ 60
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I AG F E+ + GT+ SV + +G LL + Q + +R+ IFI
Sbjct 61 RMIEAGDFFEYALVHGDWKGTARQSVEPQLAAGHDVLLEIDWQGARQVRSKIPDAISIFI 120
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS+ L L K G++ + + EM + FD I+N + A E+
Sbjct 121 LPPSRAALEERLRKRGQDSEEVIHLRLAAAHEEM--AHYDEFDYTIINEHFETAVSEMSA 178
Query 658 LI--NKLDTEPQ 667
+ ++L + Q
Sbjct 179 IFTASRLRRQTQ 190
>sp|Q8GAU4|KGUA_STRKA Guanylate kinase OS=Streptomyces kasugaensis
OX=1946 GN=gmk PE=3 SV=1
Length=205
Score = 226 bits (576), Expect = 1e-68, Method: Composition-based stats.
Identities = 55/191 (29%), Positives = 88/191 (46%), Gaps = 3/191 (2%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
P R R +L GP G++ + L + + +V TTR R E G Y FV +
Sbjct 13 PDARPRLTVLSGPSGVGKSTVVAHLRTVHPEVW-LSVSATTRKPRPGEQHGVQYFFVDDE 71
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
F+ +A G+ +E EF N YGT +V + +G+ LL + Q + +R S ++
Sbjct 72 EFDKLVANGELLEWAEFAGNRYGTPRKAVLDRLEAGEPVLLEIDLQGARQVRESMADAHL 131
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
+F+APPS E L L G R + ++E FD +VN+ ++ +E
Sbjct 132 VFLAPPSWEELVRRLTGRGTEAPEIIERRL--AAAKVELAAETEFDVTLVNTSVEDVSRE 189
Query 655 LLRLINKLDTE 665
LL L+ + E
Sbjct 190 LLALMLRQSGE 200
>sp|Q7V2K9|KGUA_PROMP Guanylate kinase OS=Prochlorococcus marinus
subsp. pastoris (strain CCMP1986 / NIES-2087 / MED4) OX=59919
GN=gmk PE=3 SV=1
Length=184
Score = 225 bits (573), Expect = 1e-68, Method: Composition-based stats.
Identities = 51/185 (28%), Positives = 93/185 (50%), Gaps = 3/185 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N K+ II+ GP G+ + + L+++ KD + ++ TTR+ R E +Y+F+ + F
Sbjct 3 NLKKLIIITGPSGVGKGTVIKELLDRNKDIW-LSISATTRNPRVGEKDDLNYYFIGEERF 61
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I +F+E +F N YGT + +V + I G I LL + + K ++ + IF
Sbjct 62 KDMIDKKEFLEWAQFAGNYYGTPLSTVNEKIEKGFIVLLEIEVEGAKQIKEKFPESLSIF 121
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+ PPS+E L + G + R + E + + FD + N D+D+ +E+L
Sbjct 122 LLPPSKEELEKRIRNRGTEKEEAIDRRLSRAN--YEIASSNQFDFVLTNHDVDETVKEVL 179
Query 657 RLINK 661
++I
Sbjct 180 KIIKS 184
>sp|Q166A7|KGUA_ROSDO Guanylate kinase OS=Roseobacter denitrificans
(strain ATCC 33942 / OCh 114) OX=375451 GN=gmk PE=3 SV=1
Length=211
Score = 226 bits (576), Expect = 1e-68, Method: Composition-based stats.
Identities = 58/185 (31%), Positives = 91/185 (49%), Gaps = 5/185 (3%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R IIL P G++ L +RL + + D +V TTR+ R EV GR+YHFV AF
Sbjct 2 RRGLLIILSSPSGAGKSTLARRLRDWDTD-IEFSVSATTRAARPGEVDGREYHFVDEAAF 60
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKP--YI 594
++ ++ G +EH N YG+ V++ IN+G+ L + Q + + NS L
Sbjct 61 KSQVSNGGMLEHAHVFGNFYGSPSGPVQEAINAGRDVLFDIDWQGAQQITNSALSAHTLS 120
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IF+ PPS LR L K ++ R + + E+ ++ +D +VN DLD
Sbjct 121 IFLLPPSIRELRNRLEKRAQDDAATIARRMDKSWDEI--SHWGSYDYVLVNDDLDTTEAH 178
Query 655 LLRLI 659
L ++
Sbjct 179 LKTIV 183
>sp|Q5FS85|KGUA_GLUOX Guanylate kinase OS=Gluconobacter oxydans
(strain 621H) OX=290633 GN=gmk PE=3 SV=1
Length=208
Score = 226 bits (575), Expect = 1e-68, Method: Composition-based stats.
Identities = 52/194 (27%), Positives = 80/194 (41%), Gaps = 4/194 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
Q R +++ P G++ + L E +V TTRS R EV G YHF
Sbjct 3 QLPRRGVCLVISAPSGAGKSTIANALRASEPT-LRHSVSVTTRSPRPGEVEGVHYHFRDI 61
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
F A G+ +E E YGT V + +++G + + Q + LR +
Sbjct 62 AEFRRMAADGELLEWAEVFGRGYGTPRAPVEEALDAGHDMVFDIDWQGHRLLRAALPDDV 121
Query 594 I-IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAY 652
+ +F+ PPS E L L K + E R + K E ++ FD I+NSDLD A
Sbjct 122 VSLFVLPPSLEELERRLNKRASDHPEEIARRM--KAALDEISHWSEFDHTIINSDLDTAI 179
Query 653 QELLRLINKLDTEP 666
+ ++
Sbjct 180 SQARSVLTAARLAT 193
>sp|Q6G053|KGUA_BARQU Guanylate kinase OS=Bartonella quintana
(strain Toulouse) OX=283165 GN=gmk PE=3 SV=1
Length=221
Score = 226 bits (576), Expect = 2e-68, Method: Composition-based stats.
Identities = 55/198 (28%), Positives = 93/198 (47%), Gaps = 7/198 (4%)
Query 464 LTYEEMSLYHQPANRKR--PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQ 521
+T+ E L + +++R IL P G++ L + L+ + +V TTR RR
Sbjct 1 MTFFESELSAKKRDQRRGFLFILSSPSGAGKSTLSRLLLKDA--QLERSVSVTTRQRRPS 58
Query 522 EVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS 581
EV G YHFVS+Q FE +FIE E N YGT SV +++G+ L + Q
Sbjct 59 EVDGFHYHFVSKQEFECKRDGDEFIEWAEVHGNYYGTLRKSVENALSAGRDILFDIDYQG 118
Query 582 LKTLRNSDL-KPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFD 640
+ L+ IFI PPS + L L + ++ + + K + E + ++D
Sbjct 119 TEQLQKKMPGDTVSIFILPPSMKELILRLHRRAEDSQDIINLRL--KNAQTEMQHWRFYD 176
Query 641 TAIVNSDLDKAYQELLRL 658
++N DL+++ + +
Sbjct 177 YVVINKDLNQSASLIKSI 194
>sp|P60555|KGUA_PROMM Guanylate kinase OS=Prochlorococcus marinus
(strain MIT 9313) OX=74547 GN=gmk PE=3 SV=1
Length=189
Score = 224 bits (571), Expect = 3e-68, Method: Composition-based stats.
Identities = 51/184 (28%), Positives = 86/184 (47%), Gaps = 3/184 (2%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
A + ++ GP G+ L ++L+ + + ++ TTR R E+ G Y F++R
Sbjct 5 AAEGKLTVITGPSGVGKGSLVKQLLELHPEIW-LSISATTREARQGEIEGDHYFFLNRDR 63
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F + AG +E EF N YGT V Q ++ G+ LL + + + +R S + + I
Sbjct 64 FAELVQAGGCLEWAEFAGNRYGTPRQPVEQQLSLGRPVLLEIELEGARQVRRSFPEAFQI 123
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+APPS E L + +P+ R + E+ FD ++N +L A EL
Sbjct 124 FLAPPSFEELERRIRGRATDPEEAIQRRLARAREEL--MAQQEFDAVVINDNLQVAVIEL 181
Query 656 LRLI 659
L+
Sbjct 182 ESLM 185
>sp|Q1MJ02|KGUA_RHIJ3 Guanylate kinase OS=Rhizobium johnstonii
(strain DSM 114642 / LMG 32736 / 3841) OX=216596 GN=gmk PE=3
SV=1
Length=220
Score = 225 bits (574), Expect = 3e-68, Method: Composition-based stats.
Identities = 46/191 (24%), Positives = 83/191 (43%), Gaps = 4/191 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
Q A R +++ P G++ + + L+ ++ + +V TTR RR EV YHF S
Sbjct 10 QIARRGLMLVISSPSGAGKSTIARTLLETDR-QIGLSVSVTTRQRRPSEVEDVHYHFKSV 68
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD-LKP 592
+ FE + +E E N YGT + V Q + G+ L + Q + L+
Sbjct 69 REFERLRDSDALLEWAEVHGNFYGTPREPVEQAMGEGRDMLFDIDWQGAQQLQEKMSADV 128
Query 593 YIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAY 652
IF+ PP+ L++ L + ++ + + E+ + +D IVN DL+ A
Sbjct 129 VSIFVLPPTMTELQSRLHRRAEDSEEVIQTRLANSRAEI--AHWREYDYVIVNDDLNAAL 186
Query 653 QELLRLINKLD 663
+ ++
Sbjct 187 DAVQSIVKAER 197
>sp|Q9KX62|KGUA_MYCGA Guanylate kinase OS=Mycoplasmoides gallisepticum
(strain R(low / passage 15 / clone 2)) OX=710127 GN=gmk
PE=3 SV=2
Length=195
Score = 224 bits (571), Expect = 3e-68, Method: Composition-based stats.
Identities = 48/193 (25%), Positives = 94/193 (49%), Gaps = 2/193 (1%)
Query 469 MSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDY 528
+ +Y + I++ GP G+ + RL++ + ++ TTR +R EV G Y
Sbjct 2 VVIYIMSNKQGLIILISGPSGVGKGTIVSRLLSDNNLKLNVSISATTRKKRASEVEGVHY 61
Query 529 HFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS 588
F +++ FE IA + +E+ + N YGT + V+++++ + +L + Q + +
Sbjct 62 FFKTKEEFEQMIANNQLLEYANYVNNYYGTPLSLVKEILDKNENLILEIEYQGVIQVLRK 121
Query 589 DLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDL 648
+ IF+ PPS++ L A L K G + + +E + +D I+N DL
Sbjct 122 GFRTLSIFVLPPSEDELVARLKKRGTENDEVIKHRLEQAVKEY--AHRELYDHTIINDDL 179
Query 649 DKAYQELLRLINK 661
+K +++ +LI K
Sbjct 180 EKTIEDIKQLILK 192
>sp|Q1QKV7|KGUA_NITHX Guanylate kinase OS=Nitrobacter hamburgensis
(strain DSM 10229 / NCIMB 13809 / X14) OX=323097 GN=gmk
PE=3 SV=1
Length=219
Score = 225 bits (573), Expect = 4e-68, Method: Composition-based stats.
Identities = 47/188 (25%), Positives = 80/188 (43%), Gaps = 4/188 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R +L P G+ L RL+ + + + +V TTR R EV GRDY FV + F
Sbjct 13 RRGLMFVLSSPSGAGKTTL-SRLLIERVEGLSLSVSATTRPMRPGEVDGRDYRFVDKATF 71
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLR-NSDLKPYII 595
+ + +E N YGT V ++SG+ L + Q + LR + +
Sbjct 72 AVMVKCDELLEWATVFDNRYGTPRAPVEAALSSGRDVLFDIDWQGTQQLREKARADVVSV 131
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS L L ++ + E+ ++ +D ++N D+D+A+ E+
Sbjct 132 FILPPSATDLERRLHTRAQDSDEVIRGRMDRAAHEL--SHWAEYDYIVINQDIDEAFAEV 189
Query 656 LRLINKLD 663
++
Sbjct 190 QSILKAER 197
>sp|Q819T6|KGUA_BACCR Guanylate kinase OS=Bacillus cereus (strain
ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305
/ NCIMB 9373 / NCTC 2599 / NRRL B-3711) OX=226900 GN=gmk PE=3
SV=1
Length=205
Score = 224 bits (572), Expect = 4e-68, Method: Composition-based stats.
Identities = 52/186 (28%), Positives = 85/186 (46%), Gaps = 2/186 (1%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ R I+L P G+ +R+ L + E RF ++ TTR R+ EV G DY F R
Sbjct 1 MRSRRGLLIVLSRPSGVGKGTVRKELFSHEDTRFQYSISVTTRKPREGEVDGVDYFFKER 60
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ FE I K +E EF N YGT ID V + + GK L + Q ++ + +
Sbjct 61 EEFEEMIRNEKLLEWAEFVGNYYGTPIDYVEKTLQEGKDVFLEIEVQGAIQVKKAFPEGV 120
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IF+APPS L++ + G + + E+E + +D + N ++ A
Sbjct 121 FIFLAPPSLSELKSRIVGRGTETEDVIENRLTVAKEEIEMMDA--YDYVVENDQVELACD 178
Query 654 ELLRLI 659
+ ++
Sbjct 179 RIKAIV 184
>sp|Q3SRZ7|KGUA_NITWN Guanylate kinase OS=Nitrobacter winogradskyi
(strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846
/ Nb-255) OX=323098 GN=gmk PE=3 SV=1
Length=219
Score = 224 bits (572), Expect = 5e-68, Method: Composition-based stats.
Identities = 48/188 (26%), Positives = 80/188 (43%), Gaps = 4/188 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R +L P G+ L RL+ + + + +V TTR R EV GRDY FV + F
Sbjct 13 RRGLMFVLSSPSGAGKTTL-SRLLIERVEGLSLSVSATTRPMRPGEVDGRDYAFVDEKTF 71
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-I 595
A + +E N YGT V ++SG+ L + Q + LR + +
Sbjct 72 AAMVERNDLLEWAHVFDNHYGTPRAPVDAALSSGRDVLFDIDWQGTQQLREKARDDVVSV 131
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS L L ++ + E+ ++ +D ++N D+D+A+ E+
Sbjct 132 FILPPSAADLERRLHTRAQDSDDVIRERMARAAHEV--SHWAEYDYIVINRDIDEAFAEV 189
Query 656 LRLINKLD 663
++
Sbjct 190 QSILKAER 197
>sp|Q9PD76|KGUA_XYLFA Guanylate kinase OS=Xylella fastidiosa (strain
9a5c) OX=160492 GN=gmk PE=3 SV=1
Length=204
Score = 224 bits (570), Expect = 6e-68, Method: Composition-based stats.
Identities = 49/195 (25%), Positives = 84/195 (43%), Gaps = 5/195 (3%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R I+ G++ + + ++ + A ++ T+R R E + Y+FVS F+
Sbjct 2 RGTLYIVSAASGTGKSSIVNATLERD-QQIALSISFTSRQPRPNERHAQHYYFVSADEFQ 60
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I AG F E+ + GT+ SV + +G LL + Q + +RN IFI
Sbjct 61 RMIEAGDFFEYALVHDDWKGTAHQSVEPQLAAGHDVLLEIDWQGARQVRNKIPDAISIFI 120
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS+ L L K G++ + R + E + FD I+N + A E+
Sbjct 121 LPPSRAALEERLRKRGQDSEEVIHRRL--AAVHEEMAHYDEFDYTIINEHFETAVSEMSA 178
Query 658 LI--NKLDTEPQWVP 670
+ ++L + Q V
Sbjct 179 IFTASRLRRQTQKVR 193
>sp|Q5N570|KGUA_SYNP6 Guanylate kinase OS=Synechococcus sp. (strain
ATCC 27144 / PCC 6301 / SAUG 1402/1) OX=269084 GN=gmk
PE=3 SV=1
Length=183
Score = 223 bits (568), Expect = 7e-68, Method: Composition-based stats.
Identities = 51/181 (28%), Positives = 89/181 (49%), Gaps = 3/181 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
R ++L GP G+ L + ++++ + F ++ TTRS R EV G+ Y+F+SR+ F+
Sbjct 4 GRVVVLTGPSGVGKGTLLKAILSQHPEAF-LSISATTRSPRPGEVDGQHYYFLSREEFQT 62
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
IA +F+E EF NLYGT V + +N G+ +L + + + +R + + +
Sbjct 63 KIAEQEFLEWAEFAGNLYGTPRSPVIEQVNLGRTVILEIELEGARQVRKTLPSARQVVLL 122
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS E L + + + R +++ E+ FD ++N LD A L
Sbjct 123 PPSVEELEQRIRERATEDEAAIARRLLQAQTEI--GAAKEFDRCVINDQLDTAITALEAA 180
Query 659 I 659
I
Sbjct 181 I 181
>sp|Q984S9|KGUA_RHILO Guanylate kinase OS=Mesorhizobium japonicum
(strain LMG 29417 / CECT 9101 / MAFF 303099) OX=266835 GN=gmk
PE=3 SV=2
Length=218
Score = 224 bits (571), Expect = 9e-68, Method: Composition-based stats.
Identities = 48/190 (25%), Positives = 85/190 (45%), Gaps = 4/190 (2%)
Query 471 LYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
L + R ++L P G++ + + L+ + +V TTR RR E+ G YHF
Sbjct 6 LGSRIRRRGLMLVLSSPSGAGKSTIARNLLESDSS-LELSVSVTTRPRRGSEIEGVHYHF 64
Query 531 VSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL 590
+ + FE + +E E N Y T + + G+ L + Q + L+
Sbjct 65 RTMREFERLRDSDALLEWAEVHGNCYATPREPAELALAQGRDMLFDIDWQGAQQLKEKMR 124
Query 591 KPYI-IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLD 649
+ IFI PPS + L+A L + ++ + + E+E + +D IVN DLD
Sbjct 125 ADIVSIFILPPSMKELKARLKRRAEDQEAVIETRLKNARNEIE--HWKEYDFVIVNDDLD 182
Query 650 KAYQELLRLI 659
+A+ E+ ++
Sbjct 183 RAFAEVRGIV 192
>sp|Q9X215|KGUA_THEMA Guanylate kinase OS=Thermotoga maritima
(strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
OX=243274 GN=gmk PE=3 SV=1
Length=207
Score = 223 bits (568), Expect = 1e-67, Method: Composition-based stats.
Identities = 46/188 (24%), Positives = 87/188 (46%), Gaps = 3/188 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ + ++ GP G+ + + ++ + D +V TTR +R E G+DY F++ + F
Sbjct 2 KGQLFVICGPSGAGKTSIIKEVLKRL-DNVVFSVSCTTRPKRPHEEDGKDYFFITEEEFL 60
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
+ G+F+E +LYGT V IN GK +L + Q +++ I++
Sbjct 61 KRVERGEFLEWARVHGHLYGTLRSFVESHINEGKDVVLDIDVQGALSVKKKYSNTVFIYV 120
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
APPS LR + K G + + L + + E FD +VN +L+ A + ++
Sbjct 121 APPSYADLRERILKRGTEKEADVLVRLENA--KWELMFMDEFDYIVVNENLEDAVEMVVS 178
Query 658 LINKLDTE 665
++ +
Sbjct 179 IVRSERAK 186
>sp|Q28PK5|KGUA_JANSC Guanylate kinase OS=Jannaschia sp. (strain
CCS1) OX=290400 GN=gmk PE=3 SV=1
Length=218
Score = 223 bits (569), Expect = 1e-67, Method: Composition-based stats.
Identities = 56/195 (29%), Positives = 90/195 (46%), Gaps = 7/195 (4%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R IIL P G++ L +RLM + + + +V TTR R E G Y F+ F
Sbjct 8 RRGLLIILSSPSGAGKSTLARRLMAWD-ETLSFSVSATTRQARPGEEDGVHYRFLPEAEF 66
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL--KPYI 594
++ +++G+ +EH N YG+ + V Q I +G L + Q + +RNSDL
Sbjct 67 KSLVSSGQMLEHAHVFGNFYGSPMAPVSQAIEAGHDVLFDIDWQGAQQIRNSDLGKHTLS 126
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IFI PPS L+ L ++ + + + E+ + +D +VN DL +
Sbjct 127 IFILPPSIPELKRRLESRAQDSDDVIEKRMRKSWDEISR--WDAYDYVLVNDDLSVTEER 184
Query 655 LLRLI--NKLDTEPQ 667
L +I +L E Q
Sbjct 185 LKTIITAERLRREQQ 199
>sp|Q2JQB9|KGUA_SYNJA Guanylate kinase OS=Synechococcus sp. (strain
JA-3-3Ab) OX=321327 GN=gmk PE=3 SV=1
Length=217
Score = 223 bits (568), Expect = 2e-67, Method: Composition-based stats.
Identities = 55/187 (29%), Positives = 94/187 (50%), Gaps = 3/187 (2%)
Query 473 HQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVS 532
PA R R ++L GP G+ L +L + + + +V TTR R E G +Y+F +
Sbjct 24 RPPATRGRLVVLTGPSGVGKGTLVSQLRQRHPELY-FSVSVTTRPPRPGEQEGVNYYFRT 82
Query 533 RQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKP 592
R+ F I A + +E ++ N YGT + V Q ++ G+ LL + + +R
Sbjct 83 REEFLNLIEADELLEWAQYAGNFYGTPREIVFQKLSQGQDVLLEIELAGARQVRQQCPDA 142
Query 593 YIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAY 652
IF++PPS E L + + G++ + R + + +E++ FD IVN +L++A
Sbjct 143 IRIFLSPPSLEELERRIRERGQDSEASIQRRLQQARKELDAK--DEFDYVIVNDNLEQAL 200
Query 653 QELLRLI 659
QEL L+
Sbjct 201 QELEALL 207
>sp|Q215S7|KGUA_RHOPB Guanylate kinase OS=Rhodopseudomonas palustris
(strain BisB18) OX=316056 GN=gmk PE=3 SV=1
Length=219
Score = 222 bits (566), Expect = 4e-67, Method: Composition-based stats.
Identities = 47/188 (25%), Positives = 79/188 (42%), Gaps = 4/188 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R +L P G+ L RL+ + +V TTR++R E GRDY+FV F
Sbjct 13 RRGLMFVLSSPSGAGKTTL-SRLLIERVAGLKMSVSATTRTKRPGEEDGRDYYFVDHARF 71
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-I 595
+A + +E N YGT V + G+ L + Q + LR + +
Sbjct 72 QAMTENAELLEWANVFDNCYGTPRAPVEAALAVGQDVLFDIDWQGTQQLREKARDDVVSV 131
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS L L ++ + + E+ ++ +D +VN D+D+A+ E+
Sbjct 132 FILPPSAADLEKRLHTRAQDSDEVIRGRMSRASHEL--SHFAEYDYIVVNHDIDEAFAEV 189
Query 656 LRLINKLD 663
++
Sbjct 190 HSILKAER 197
>sp|Q2IL45|KGUA_ANADE Guanylate kinase OS=Anaeromyxobacter dehalogenans
(strain 2CP-C) OX=290397 GN=gmk PE=3 SV=1
Length=226
Score = 222 bits (566), Expect = 6e-67, Method: Composition-based stats.
Identities = 49/202 (24%), Positives = 84/202 (42%), Gaps = 5/202 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
Q ++L P G+ L RL D ++ TTR+ R E G DYHFV+
Sbjct 8 QERLPGLLLVLSAPSGAGKTTLAHRLREASPDAV-FSISATTRAPRGAEREGVDYHFVTA 66
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL-KP 592
+ F +A G F E E YGT +V + + +GK+ L + Q ++ + +
Sbjct 67 ERFTELVAQGAFAEWAEVHGQRYGTLRATVDEALAAGKLALFDIDVQGGAQIKAAWPQQA 126
Query 593 YIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAY 652
+ + PP + L L + R ++ E+ + G +D +VN L+ A
Sbjct 127 ATVLVLPPDEAELERRLRGRDTDSDETIRRRLVAARAEVARGLGS-YDYVVVNDVLEGAL 185
Query 653 QELLRLI--NKLDTEPQWVPST 672
+L ++ +L +W P
Sbjct 186 AQLQAIVRHERLRHAGRWDPEA 207
>sp|Q0BPZ9|KGUA_GRABC Guanylate kinase OS=Granulibacter bethesdensis
(strain ATCC BAA-1260 / CGDNIH1) OX=391165 GN=gmk PE=3
SV=1
Length=213
Score = 221 bits (564), Expect = 6e-67, Method: Composition-based stats.
Identities = 47/208 (23%), Positives = 93/208 (45%), Gaps = 7/208 (3%)
Query 469 MSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDY 528
M + R +++ P G++ + + L+ ++ +V TTR+ R E G Y
Sbjct 2 MRPLPETGRRGLCLVVAAPSGAGKSSITRALLAEDPG-LRLSVSVTTRAPRAGEQEGVHY 60
Query 529 HFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS 588
+F +++ F+A A G+ +E+ YGT V++ ++ G L + Q LR++
Sbjct 61 YFRTQEEFDAMAAEGQLLEYARVFGRSYGTPRGPVQKALSEGSDVLFDVDWQGYHQLRSA 120
Query 589 DLKPYI-IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD 647
+ IF+ PPS + L + L G + + + E+ + F +VN+
Sbjct 121 LPGDVVGIFVLPPSLDDLASRLEGRG-DAPDIIAQRMAAARDEI--AHVGEFPYVVVNTH 177
Query 648 LDKAYQELLRLINKLDTEPQWVPSTWLR 675
L +A ++ +++ TE + WLR
Sbjct 178 LPEAIDQVRTILHAARTETK--RQGWLR 203
>sp|Q2J840|KGUA_FRACC Guanylate kinase OS=Frankia casuarinae (strain
DSM 45818 / CECT 9043 / HFP020203 / CcI3) OX=106370 GN=gmk
PE=3 SV=1
Length=184
Score = 220 bits (561), Expect = 6e-67, Method: Composition-based stats.
Identities = 48/179 (27%), Positives = 82/179 (46%), Gaps = 3/179 (2%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
+L GP G++ + + + + + +V TTR R E G +YHFV + F +
Sbjct 6 LTVLSGPSGVGKDTVVAAVRERHPEVW-VSVSATTRPPRPGETDGVEYHFVDAEEFARMV 64
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
AG+F+EH F + YGT + + + +G CLL + + +R++ + +F+APP
Sbjct 65 KAGEFVEHAMFAGHAYGTPRRPLLERLAAGVPCLLEIELLGARQVRSAMPQARFVFLAPP 124
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
+ + L L G R + +E FD IVN D+ A L+ L+
Sbjct 125 TFDELVRRLTGRGTESPEVIARRL--DRARIELAAETEFDDVIVNDDVRSAAARLVALM 181
>sp|Q5GS56|KGUA_WOLTR Guanylate kinase OS=Wolbachia sp. subsp.
Brugia malayi (strain TRS) OX=292805 GN=gmk PE=3 SV=1
Length=195
Score = 221 bits (562), Expect = 7e-67, Method: Composition-based stats.
Identities = 53/188 (28%), Positives = 90/188 (48%), Gaps = 4/188 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N ++L P G+ + +RL+ + +V TTR R E+ G+DY FV+++ F
Sbjct 5 NEGVLLVLSSPSGAGKTTILERLL-ERSTNLVRSVSMTTRKPRPGEINGKDYFFVTKKEF 63
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK-PYII 595
AG+ +E+ +N YG + Q ++SG LLS+ Q L + +
Sbjct 64 HELCEAGQMLEYARVFENFYGIPKSFIEQNLSSGISVLLSIDWQGAFHLFELMREKVISV 123
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS E LR L K + E + E +EM + +D ++N D+DK+ +E+
Sbjct 124 FILPPSMEELRLRLQKRNSDSASEIEHRLAEAQKEMSKR--DKYDYVVINDDIDKSVEEI 181
Query 656 LRLINKLD 663
+++K
Sbjct 182 SSILDKER 189
>sp|Q9ZMB7|KGUA_HELPJ Guanylate kinase OS=Helicobacter pylori
(strain J99 / ATCC 700824) OX=85963 GN=gmk PE=3 SV=1
Length=206
Score = 221 bits (563), Expect = 7e-67, Method: Composition-based stats.
Identities = 53/179 (30%), Positives = 88/179 (49%), Gaps = 3/179 (2%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
+IL GP G++ L + L K + ++ TTR R+ EV G Y+FVS + F+
Sbjct 6 NLLILSGPSGAGKSTLTKYLQEKIP-KTHFSLSTTTRKPREGEVDGLHYNFVSEEEFKQG 64
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
I G+F+E + YGTS V + + GKI + + Q + L+ +FI+
Sbjct 65 IEKGQFLEWAIVHNHYYGTSKIPVEKALKEGKIVIFDIDVQGHEILKKHYPNACSVFIST 124
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
+QE L+ L G + K + +I +EM+ FD I+N DL+K+ + +L +
Sbjct 125 KNQEILKERLLLRGTDSKETIEKRLINAYKEMQCLES--FDYLIINEDLEKSKEIILSI 181
>sp|Q2JQ59|KGUA_SYNJB Guanylate kinase OS=Synechococcus sp. (strain
JA-2-3B'a(2-13)) OX=321332 GN=gmk PE=3 SV=1
Length=221
Score = 222 bits (565), Expect = 7e-67, Method: Composition-based stats.
Identities = 56/185 (30%), Positives = 92/185 (50%), Gaps = 3/185 (2%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
P R R ++L GP G+ L +L + + + +V TTR R E G +Y+F SR+
Sbjct 28 PTPRGRLVVLTGPSGVGKGTLVNQLRQRHPELY-LSVSVTTRPPRPSEQEGVNYYFRSRE 86
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
F I A + +E ++ N YGT + V Q +N G+ LL + + +R
Sbjct 87 EFLNLIEANELLEWAQYAGNFYGTPREIVFQKLNQGQDVLLEIELAGARQVRQQYPDAIR 146
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
IF+ PPS E L + + G++ + R + + +E++ FD IVN +L++A QE
Sbjct 147 IFLCPPSLEELERRIRERGQDSEASIERRLEQARKELDAQ--DEFDYVIVNDNLEQALQE 204
Query 655 LLRLI 659
L L+
Sbjct 205 LEALL 209
>sp|P56103|KGUA_HELPY Guanylate kinase OS=Helicobacter pylori
(strain ATCC 700392 / 26695) OX=85962 GN=gmk PE=3 SV=1
Length=206
Score = 221 bits (563), Expect = 8e-67, Method: Composition-based stats.
Identities = 53/179 (30%), Positives = 88/179 (49%), Gaps = 3/179 (2%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
+IL GP G++ L + L K + ++ TTR R+ EV G Y+FVS + F+
Sbjct 6 NLLILSGPSGAGKSTLTKYLQEKIP-KTHFSLSTTTRKPREGEVDGLHYNFVSEEEFKQG 64
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
I G+F+E + YGTS V + + GKI + + Q + L+ +FI+
Sbjct 65 IEKGQFLEWAIVHNHYYGTSKIPVEKALKEGKIVIFDIDVQGHEILKKHYPNACSVFIST 124
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
+QE L+ L G + K + +I +EM+ FD I+N DL+K+ + +L +
Sbjct 125 KNQEILKERLLLRGTDSKETIEKRLINAYKEMQCLES--FDYLIINEDLEKSKEIILSI 181
>sp|Q1CUI1|KGUA_HELPH Guanylate kinase OS=Helicobacter pylori
(strain HPAG1) OX=357544 GN=gmk PE=3 SV=1
Length=206
Score = 221 bits (562), Expect = 1e-66, Method: Composition-based stats.
Identities = 53/179 (30%), Positives = 88/179 (49%), Gaps = 3/179 (2%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
+IL GP G++ L + L K + ++ TTR R+ EV G Y+FVS + F+
Sbjct 6 NLLILSGPSGAGKSTLTKYLQEKIP-KTHFSLSTTTRKPREGEVDGLHYNFVSEEEFKQG 64
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
I G+F+E + YGTS V + + GKI + + Q + L+ +FI+
Sbjct 65 IEKGQFLEWAIVHNHYYGTSKIPVEKALKEGKIVIFDIDVQGHEILKKHYPNACSVFIST 124
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
+QE L+ L G + K + +I +EM+ FD I+N DL+K+ + +L +
Sbjct 125 KNQEILKERLLLRGTDSKETIEKRLINAYKEMQCLES--FDYLIINEDLEKSKEIILSI 181
>sp|Q1AVZ3|KGUA_RUBXD Guanylate kinase OS=Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129 / PRD-1) OX=266117 GN=gmk
PE=3 SV=1
Length=191
Score = 220 bits (560), Expect = 1e-66, Method: Composition-based stats.
Identities = 56/186 (30%), Positives = 92/186 (49%), Gaps = 3/186 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R R I++ GP G++ L + ++ + A +V TTR+ R EV GRDY F+SR+ F
Sbjct 2 RRGRLIVVSGPSGAGKSTLIRAALDAVP-QLAYSVSATTRAPRPGEVNGRDYIFLSREEF 60
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
E I G+F+E E+ NLYGT V + + SG +L + Q + +R +IF
Sbjct 61 ERWIREGRFLEWAEYSGNLYGTPAHRVEEYLESGLSVILEIELQGARKVRRKRPDAVMIF 120
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+ PS E R L + R + E+ FD +VN D ++A +E++
Sbjct 121 VRAPSLEETRRRLEGRATESEDAVQRRLATAVEEV--AARDEFDCEVVNDDYERAREEMI 178
Query 657 RLINKL 662
++ ++
Sbjct 179 EIMRRI 184
>sp|P9WKE9|KGUA_MYCTU Guanylate kinase OS=Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv) OX=83332 GN=gmk PE=1 SV=1
Length=208
Score = 221 bits (562), Expect = 1e-66, Method: Composition-based stats.
Identities = 53/188 (28%), Positives = 86/188 (46%), Gaps = 5/188 (3%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
QPA R ++L GP G++ + + L + + +V TTR+ R EV G DYHF+
Sbjct 16 QPAAVGRVVVLSGPSAVGKSTVVRCLRERIPN-LHFSVSATTRAPRPGEVDGVDYHFIDP 74
Query 534 QAFEADIAAGKFIEHGEFEK--NLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK 591
F+ I G+ +E E + GT VR +G L+ + + ++ + +
Sbjct 75 TRFQQLIDQGELLEWAEIHGGLHRSGTLAQPVRAAAATGVPVLIEVDLAGARAIKKTMPE 134
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
+F+APPS + L+A L G R + T +E FD +VN L+ A
Sbjct 135 AVTVFLAPPSWQDLQARLIGRGTETADVIQRRL--DTARIELAAQGDFDKVVVNRRLESA 192
Query 652 YQELLRLI 659
EL+ L+
Sbjct 193 CAELVSLL 200
>sp|P9WKE8|KGUA_MYCTO Guanylate kinase OS=Mycobacterium tuberculosis
(strain CDC 1551 / Oshkosh) OX=83331 GN=gmk PE=3 SV=1
Length=208
Score = 221 bits (562), Expect = 1e-66, Method: Composition-based stats.
Identities = 53/188 (28%), Positives = 86/188 (46%), Gaps = 5/188 (3%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
QPA R ++L GP G++ + + L + + +V TTR+ R EV G DYHF+
Sbjct 16 QPAAVGRVVVLSGPSAVGKSTVVRCLRERIPN-LHFSVSATTRAPRPGEVDGVDYHFIDP 74
Query 534 QAFEADIAAGKFIEHGEFEK--NLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK 591
F+ I G+ +E E + GT VR +G L+ + + ++ + +
Sbjct 75 TRFQQLIDQGELLEWAEIHGGLHRSGTLAQPVRAAAATGVPVLIEVDLAGARAIKKTMPE 134
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
+F+APPS + L+A L G R + T +E FD +VN L+ A
Sbjct 135 AVTVFLAPPSWQDLQARLIGRGTETADVIQRRL--DTARIELAAQGDFDKVVVNRRLESA 192
Query 652 YQELLRLI 659
EL+ L+
Sbjct 193 CAELVSLL 200
>sp|P0A5I5|KGUA_MYCBO Guanylate kinase OS=Mycobacterium bovis
(strain ATCC BAA-935 / AF2122/97) OX=233413 GN=gmk PE=3 SV=1
Length=208
Score = 221 bits (562), Expect = 1e-66, Method: Composition-based stats.
Identities = 53/188 (28%), Positives = 86/188 (46%), Gaps = 5/188 (3%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
QPA R ++L GP G++ + + L + + +V TTR+ R EV G DYHF+
Sbjct 16 QPAAVGRVVVLSGPSAVGKSTVVRCLRERIPN-LHFSVSATTRAPRPGEVDGVDYHFIDP 74
Query 534 QAFEADIAAGKFIEHGEFEK--NLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK 591
F+ I G+ +E E + GT VR +G L+ + + ++ + +
Sbjct 75 TRFQQLIDQGELLEWAEIHGGLHRSGTLAQPVRAAAATGVPVLIEVDLAGARAIKKTMPE 134
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
+F+APPS + L+A L G R + T +E FD +VN L+ A
Sbjct 135 AVTVFLAPPSWQDLQARLIGRGTETADVIQRRL--DTARIELAAQGDFDKVVVNRRLESA 192
Query 652 YQELLRLI 659
EL+ L+
Sbjct 193 CAELVSLL 200
>sp|Q73HV1|KGUA_WOLPM Guanylate kinase OS=Wolbachia pipientis
wMel OX=163164 GN=gmk PE=3 SV=2
Length=201
Score = 220 bits (560), Expect = 2e-66, Method: Composition-based stats.
Identities = 54/183 (30%), Positives = 90/183 (49%), Gaps = 4/183 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
++L P G+ + +L+ + +V TTR R E+ G+DY FV+ + F
Sbjct 7 GVLLVLSSPSGAGKTTISAKLLEQ-STNLVRSVSMTTRKPRPGEINGKDYFFVTEEKFHE 65
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTL-RNSDLKPYIIFI 597
AG+ +E+ + +N YG D + Q ++SG LLS+ Q L + K +FI
Sbjct 66 LCKAGQMLEYAKVFENFYGIPRDFIEQNLSSGISVLLSIDWQGAFHLFKLMRKKVVSVFI 125
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS E LR L K + E R + E +E+ + +D I+N D+DK+ +E+
Sbjct 126 LPPSMEELRLRLQKRNSDDASEIERRLAEAQKEISKR--DKYDYVIINDDIDKSVEEISS 183
Query 658 LIN 660
++N
Sbjct 184 ILN 186
>sp|Q6AJ91|KGUA_DESPS Guanylate kinase OS=Desulfotalea psychrophila
(strain LSv54 / DSM 12343) OX=177439 GN=gmk PE=3 SV=1
Length=203
Score = 220 bits (560), Expect = 2e-66, Method: Composition-based stats.
Identities = 57/197 (29%), Positives = 86/197 (44%), Gaps = 4/197 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N+ + ++ P G+ + R+M R ++ HTTR+ R E G DYHFV ++ F
Sbjct 2 NKGKLFVISAPSGAGKTTILGRVMA-NVGRLNFSISHTTRTARPGEQDGVDYHFVEQEDF 60
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD-LKPYII 595
G F+E KN YGTS ++V ++ G +L + Q L S L I
Sbjct 61 IEMQEKGIFLESAYVHKNYYGTSREAVMAQLSEGVDVVLDIDVQGATILMESASLPATYI 120
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FIAPP L L K G + + + EM + +D IVN DL +A L
Sbjct 121 FIAPPDLSVLEERLRKRGSDSEETIKLRMGNAAGEM--LSSRKYDYLIVNDDLAQASTLL 178
Query 656 LRLINKLDTEPQWVPST 672
+I + + P+
Sbjct 179 KSIIWAERAKSRRTPAG 195
>sp|Q255A8|KGUA_CHLFF Guanylate kinase OS=Chlamydia felis (strain
Fe/C-56) OX=264202 GN=gmk PE=3 SV=1
Length=204
Score = 219 bits (559), Expect = 3e-66, Method: Composition-based stats.
Identities = 53/186 (28%), Positives = 84/186 (45%), Gaps = 3/186 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+P + + P G+ L + L + D F V TTRS R +EV G DY+FVS+
Sbjct 13 RPLCVPKLFTISAPAGAGKTTLVRMLAEEFPDSFQKTVSLTTRSPRPEEVHGVDYYFVSQ 72
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ F + +G F+E YGTS + ++ SGK + + + LR+
Sbjct 73 EEFLKRLDSGDFLEWVALFGEYYGTSRLEIDKIWKSGKHAIAVIDVEGALALRSKIP-TV 131
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI+ PS E L L G + + + +EQ F+ I+N DL+K+Y+
Sbjct 132 TIFISAPSLEELERRLKHRGSEQDAQRQERL--QHSLIEQAASSKFEYVIINDDLEKSYE 189
Query 654 ELLRLI 659
L +
Sbjct 190 ILKSIF 195
>sp|Q1B9F6|KGUA_MYCSS Guanylate kinase OS=Mycobacterium sp. (strain
MCS) OX=164756 GN=gmk PE=3 SV=1
Length=198
Score = 219 bits (558), Expect = 3e-66, Method: Composition-based stats.
Identities = 52/183 (28%), Positives = 85/183 (46%), Gaps = 5/183 (3%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
R ++L GP G++ + + L + D + +V TTR+ R EV G DY FV+ +AF+
Sbjct 8 GRVVVLSGPSAVGKSTVVRCLRERIPDLY-FSVSATTRAPRPGEVDGVDYSFVTPEAFQQ 66
Query 539 DIAAGKFIEHGEFEK--NLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
I G +E E + GT VR+ +G+ L+ + + ++ + + +F
Sbjct 67 LIDDGALLEWAEIHGGLHRSGTPARPVREATVAGRPVLIEVDLAGARAVKQAMPEALSVF 126
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+APPS E L L G R + E+ FD +VNS L+ A EL+
Sbjct 127 LAPPSWEVLERRLVGRGTETPDVMSRRLDTARTEL--AAQSDFDVVVVNSQLESACSELV 184
Query 657 RLI 659
L+
Sbjct 185 SLL 187
>sp|Q7NK59|KGUA_GLOVI Guanylate kinase OS=Gloeobacter violaceus
(strain ATCC 29082 / PCC 7421) OX=251221 GN=gmk PE=3 SV=1
Length=205
Score = 219 bits (558), Expect = 3e-66, Method: Composition-based stats.
Identities = 56/205 (27%), Positives = 89/205 (43%), Gaps = 10/205 (5%)
Query 469 MSLYHQPANRK------RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQE 522
M Y + A R ++L GP G++ + + + + + +V TTR R E
Sbjct 1 MPFYRRSAGSPAGHPLSRLLVLSGPSGVGKDTILREVRERHPGLY-VSVSATTRPPRPGE 59
Query 523 VAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSL 582
V GRDY F+S FE IA +E + N YGT V + + G+ +L + Q
Sbjct 60 VDGRDYRFLSAAEFEEWIATDDLLEWACYVGNYYGTPKTPVLERLAVGEPVVLEIDVQGA 119
Query 583 KTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTA 642
++N+ ++FI PPS E L L G + R + E+ FD
Sbjct 120 LQVKNNFPAAMLVFIRPPSLEVLAERLRSRGTDAPEAIERRLARAREELAL--ADRFDHQ 177
Query 643 IVNSDLDKAYQELLRLI-NKLDTEP 666
+VN L A + + RL+ ++ EP
Sbjct 178 VVNDKLAAAVEAVERLLFEEIPDEP 202
>sp|P47353|KGUA_MYCGE Guanylate kinase OS=Mycoplasma genitalium
(strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37) OX=243273
GN=gmk PE=3 SV=2
Length=240
Score = 220 bits (561), Expect = 4e-66, Method: Composition-based stats.
Identities = 48/184 (26%), Positives = 81/184 (44%), Gaps = 3/184 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N+ R ++ GP G++ L + L++ K++ ++ TTR +R E G DY F + F
Sbjct 54 NQGRIFVITGPSGVGKSTLVKALLDHFKEQLFYSISATTRKKRISEKEGIDYFFKDKDEF 113
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL-KPYII 595
E I FIE + + YGT Q I SG +L + Q +++ +I
Sbjct 114 ENLIKQDAFIEWACYNNHYYGTLKSQAEQAIKSGINLMLEIEYQGALQVKSKYPHNVVLI 173
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS + L L K + + + + ++E F + N + DK EL
Sbjct 174 FIKPPSMQELLKRLKKRNDEDETTIKKRLEQA--KIEFQQIDNFKYVVTNKEFDKTLNEL 231
Query 656 LRLI 659
++
Sbjct 232 KSIL 235
>sp|Q9A7N9|KGUA_CAUVC Guanylate kinase OS=Caulobacter vibrioides
(strain ATCC 19089 / CB15) OX=190650 GN=gmk PE=3 SV=1
Length=213
Score = 219 bits (558), Expect = 4e-66, Method: Composition-based stats.
Identities = 51/196 (26%), Positives = 89/196 (45%), Gaps = 5/196 (3%)
Query 469 MSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDY 528
M+ H P +R ++++ P G+ L +RL++ D ++ TTR R E GRDY
Sbjct 1 MNKSHHP-HRGLLLMVVAPSGVGKTSLTRRLVSDHGD-LHLSISATTRDPRPGEHDGRDY 58
Query 529 HFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTL-RN 587
HFVSR F+ +A F+E E N YG+ + ++ G+ L + Q + +
Sbjct 59 HFVSRDKFQGMLAEDAFLEWAEVYGNFYGSPKAPIMDALSRGESVLFDIDFQGAMKVHKQ 118
Query 588 SDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD 647
+ +++I PPS + L ++ + R + + E FD I+N D
Sbjct 119 AGADSVLVYILPPSLAEMSRRLHTRSQDSEEVIHRRL--SRAKDEVAAWEQFDYVILNDD 176
Query 648 LDKAYQELLRLINKLD 663
D+AY +L + +
Sbjct 177 FDRAYADLAHIYHAER 192
>sp|Q1D3A6|KGUA_MYXXD Guanylate kinase OS=Myxococcus xanthus (strain
DK1622) OX=246197 GN=gmk PE=3 SV=1
Length=209
Score = 219 bits (557), Expect = 5e-66, Method: Composition-based stats.
Identities = 43/175 (25%), Positives = 76/175 (43%), Gaps = 2/175 (1%)
Query 485 IGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGK 544
P G+ L RL+ + D ++ TTR R +E G DY+FV F++ I G+
Sbjct 16 SAPSGAGKTTLAHRLLKETPDAV-FSISVTTRRPRGKEREGVDYNFVDVATFQSKIERGE 74
Query 545 FIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQER 604
F+E E + YG+ V + + + Q + ++ IF+ PPS E
Sbjct 75 FVEWAEVYGHFYGSPQSVVDEARARKSAAIFDIDVQGGQAIKRKHPDAVTIFVLPPSMEE 134
Query 605 LRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
L L + R ++ E+E+ +D +VN D ++A+ +L ++
Sbjct 135 LERRLRDRQTDSDETIRRRMLAARSEIERGIAS-YDYVVVNDDFERAFSDLRSVV 188
>sp|Q0C093|KGUA_HYPNA Guanylate kinase OS=Hyphomonas neptunium
(strain ATCC 15444) OX=228405 GN=gmk PE=3 SV=1
Length=217
Score = 219 bits (557), Expect = 9e-66, Method: Composition-based stats.
Identities = 51/184 (28%), Positives = 80/184 (43%), Gaps = 4/184 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R ++L P G+ L + L+ + D ++ TTR R EV G DY+F + F
Sbjct 13 RRGLMLVLSSPSGAGKTTLSRMLLEEFGD-VKLSISATTRPPRPNEVHGEDYYFKTPDEF 71
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-I 595
I +F+E YGT + +G+ L + Q L + + +
Sbjct 72 HRMIERREFLEWAHVFDKHYGTPKADTVARLEAGEDVLFDVDWQGADALHDQMPNDVVSV 131
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS E L+A L + R + + RE+ + +D IVN DL+ AYQ L
Sbjct 132 FILPPSIEALQARLMGRPGSTPELVARRMEDAKREI--MHWRRYDYVIVNDDLNVAYQRL 189
Query 656 LRLI 659
R++
Sbjct 190 KRIL 193
>sp|Q6MDG3|KGUA_PARUW Guanylate kinase OS=Protochlamydia amoebophila
(strain UWE25) OX=264201 GN=gmk PE=3 SV=1
Length=197
Score = 218 bits (555), Expect = 9e-66, Method: Composition-based stats.
Identities = 54/182 (30%), Positives = 84/182 (46%), Gaps = 4/182 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ I+ P G+ L L+ + A ++ +TTR+ R EV G+DY+F++ FE
Sbjct 9 KGSLFIVSAPAGTGKTTLVNLLVQEFPTVIA-SISYTTRAPRLGEVNGKDYYFITESEFE 67
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
A IAA F+E+ + YGTS + V G +L + TQ L+ + IFI
Sbjct 68 AKIAAADFLEYVKLYDTYYGTSREWVEIQRQLGLHVILVIDTQGALQLQKLC-EATFIFI 126
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS + L+ L + + E E Y+D I+N DL +AYQ L
Sbjct 127 RPPSLDELKNRLINRQTESLEMIEKRL--ACAERELEAAQYYDYEIINDDLQEAYQVLRS 184
Query 658 LI 659
++
Sbjct 185 IL 186
>sp|Q2A2K6|KGUA_FRATH Guanylate kinase OS=Francisella tularensis
subsp. holarctica (strain LVS) OX=376619 GN=gmk PE=3 SV=1
Length=190
Score = 218 bits (554), Expect = 1e-65, Method: Composition-based stats.
Identities = 51/184 (28%), Positives = 89/184 (48%), Gaps = 5/184 (3%)
Query 481 PIILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
I+ P G++ L + + + KD +A A+ HTTR R E+ R+Y+FV+ FE
Sbjct 5 IFIISAPSGAGKSSLLKAFLATDIGKDNYAVAISHTTREPRVGEINSREYYFVTVAEFEQ 64
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK-PYIIFI 597
++ FIE+ + KN YGTS + +++ GK +L + Q + R IFI
Sbjct 65 LLSQDGFIEYAKVFKNYYGTSKAELDRLLALGKNIILEIDWQGAQQTRAIYGDRAKSIFI 124
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS + LR L K + K + + E+ ++ +D +VN D ++ ++L +
Sbjct 125 LPPSLDELRKRLEKRNTDSKETIDYRMEQVQSEI--SHADEYDYLLVNDDFSQSLEQLCK 182
Query 658 LINK 661
+
Sbjct 183 YFEQ 186
>sp|Q5NEY6|KGUA_FRATT Guanylate kinase OS=Francisella tularensis
subsp. tularensis (strain SCHU S4 / Schu 4) OX=177416 GN=gmk
PE=3 SV=1
Length=190
Score = 217 bits (553), Expect = 1e-65, Method: Composition-based stats.
Identities = 50/184 (27%), Positives = 88/184 (48%), Gaps = 5/184 (3%)
Query 481 PIILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
I+ P G++ L + + + KD +A A+ HTTR R E+ R+Y+FV+ FE
Sbjct 5 IFIVSAPSGAGKSSLLKAFLATDIGKDNYAVAISHTTREPRVGEINSREYYFVTVAEFEQ 64
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK-PYIIFI 597
++ FIE+ + KN YGTS + +++ GK +L + Q + R IFI
Sbjct 65 LLSQDGFIEYAKVFKNYYGTSKAELDRLLALGKNIILEIDWQGAQQTRAIYGDRAKSIFI 124
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS + LR L K + K + + E+ ++ +D +VN D ++ ++ +
Sbjct 125 LPPSLDELRKRLEKRNTDSKETIDYRMEQAQSEI--SHADEYDYLLVNDDFSQSLEQFCK 182
Query 658 LINK 661
+
Sbjct 183 YFEQ 186
>sp|Q14GD9|KGUA_FRAT1 Guanylate kinase OS=Francisella tularensis
subsp. tularensis (strain FSC 198) OX=393115 GN=gmk PE=3
SV=1
Length=190
Score = 217 bits (553), Expect = 1e-65, Method: Composition-based stats.
Identities = 50/184 (27%), Positives = 88/184 (48%), Gaps = 5/184 (3%)
Query 481 PIILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
I+ P G++ L + + + KD +A A+ HTTR R E+ R+Y+FV+ FE
Sbjct 5 IFIVSAPSGAGKSSLLKAFLATDIGKDNYAVAISHTTREPRVGEINSREYYFVTVAEFEQ 64
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK-PYIIFI 597
++ FIE+ + KN YGTS + +++ GK +L + Q + R IFI
Sbjct 65 LLSQDGFIEYAKVFKNYYGTSKAELDRLLALGKNIILEIDWQGAQQTRAIYGDRAKSIFI 124
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS + LR L K + K + + E+ ++ +D +VN D ++ ++ +
Sbjct 125 LPPSLDELRKRLEKRNTDSKETIDYRMEQAQSEI--SHADEYDYLLVNDDFSQSLEQFCK 182
Query 658 LINK 661
+
Sbjct 183 YFEQ 186
>sp|Q31C67|KGUA_PROM9 Guanylate kinase OS=Prochlorococcus marinus
(strain MIT 9312) OX=74546 GN=gmk PE=3 SV=1
Length=184
Score = 216 bits (550), Expect = 3e-65, Method: Composition-based stats.
Identities = 47/184 (26%), Positives = 93/184 (51%), Gaps = 3/184 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N+K+ IIL GP G+ + + ++ K+K+ + ++ TTR R+ E G +Y+F+ ++ F
Sbjct 3 NQKKLIILTGPSGVGKGTVIKEILGKDKNIW-LSISATTREPREGEQEGENYYFLKQEKF 61
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ I F+E +F N YGT + SV + I G LL + + K ++ + IF
Sbjct 62 KEMIEKNLFLEWAQFAGNYYGTPLSSVNEKITKGFTVLLEIEVEGAKQIKEKFPESLSIF 121
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+ PP + L + G + + ++ + E + + FD + N ++D+ + ++
Sbjct 122 LLPPDKAELERRIRNRGTEKEEAIKKRLLRAS--YEISASNQFDFELTNHNVDETAKRII 179
Query 657 RLIN 660
+LI
Sbjct 180 KLIQ 183
>sp|Q1IK22|KGUA_KORVE Guanylate kinase OS=Koribacter versatilis
(strain Ellin345) OX=204669 GN=gmk PE=3 SV=1
Length=233
Score = 218 bits (554), Expect = 4e-65, Method: Composition-based stats.
Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 4/183 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
I+ P G++ L L + ++ +TTR+ R E GR+Y FV+R+ F+A
Sbjct 3 GTIFIISAPSGSGKSSLVNELRHVVPG-LEFSISYTTRAPRGSEQNGREYFFVTREKFDA 61
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+AA +F+EH E YGT+ V + + G +L + Q L+ IFI
Sbjct 62 MLAADEFLEHAEVFGECYGTAKHFVTEALARGNDLVLDIDVQGAAQLKVKLPDAVGIFIL 121
Query 599 PPSQERLRALLAKEGKNP--KPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
PPS++ L A L + + PE + ++ + E N ++D +VN + + A ++L
Sbjct 122 PPSRKELEARLKRRNLSDHVAPEVIERRLKGAGK-EIENFSHYDYILVNDNFETAVEQLR 180
Query 657 RLI 659
++
Sbjct 181 AIV 183
>sp|P75526|KGUA_MYCPN Guanylate kinase OS=Mycoplasma pneumoniae
(strain ATCC 29342 / M129 / Subtype 1) OX=272634 GN=gmk PE=3
SV=1
Length=239
Score = 218 bits (554), Expect = 5e-65, Method: Composition-based stats.
Identities = 52/187 (28%), Positives = 83/187 (44%), Gaps = 3/187 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ + R ++ GP G++ L + L++ KD+ ++ TTR R+ E G DY F +
Sbjct 50 EMVDTGRIFVITGPSGVGKSSLVRCLIDHFKDKLRYSISATTRKMRNSETEGVDYFFKDK 109
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
FE IAA F+E + N YGT Q+I++G +L + Q ++
Sbjct 110 AEFEKLIAADAFVEWAMYNDNYYGTLKSQAEQIIHNGGNLVLEIEYQGALQVKQKYPNDV 169
Query 594 I-IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAY 652
+ IFI PPS E L L K + K E E +F + N++ DK
Sbjct 170 VLIFIKPPSMEELLVRLKKRNDEDAITIQNRL--KQAEKECQQIGHFKYVVTNNEFDKTL 227
Query 653 QELLRLI 659
EL ++
Sbjct 228 AELQAIL 234
>sp|Q0BL54|KGUA_FRATO Guanylate kinase OS=Francisella tularensis
subsp. holarctica (strain OSU18) OX=393011 GN=gmk PE=3 SV=1
Length=190
Score = 216 bits (549), Expect = 5e-65, Method: Composition-based stats.
Identities = 51/184 (28%), Positives = 89/184 (48%), Gaps = 5/184 (3%)
Query 481 PIILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
I+ P G++ L + + + KD +A A+ HTTR R E+ R+Y+FV+ FE
Sbjct 5 IFIISAPSGAGKSSLLKAFLATDIGKDNYAVAISHTTREPRVGEINSREYYFVTVAEFEQ 64
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK-PYIIFI 597
++ FIE+ + KN YGTS + +++ GK +L + Q + R IFI
Sbjct 65 LLSQDGFIEYAKVFKNYYGTSKAELDRLLALGKNIILEINWQGAQQTRAIYGDRAKSIFI 124
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS + LR L K + K + + E+ ++ +D +VN D ++ ++L +
Sbjct 125 LPPSLDELRKRLEKRNTDSKETIDYRMEQVQSEI--SHADEYDYLLVNDDFSQSLEQLCK 182
Query 658 LINK 661
+
Sbjct 183 YFEQ 186
>sp|Q5HTT7|KGUA_CAMJR Guanylate kinase OS=Campylobacter jejuni
(strain RM1221) OX=195099 GN=gmk PE=3 SV=1
Length=205
Score = 216 bits (550), Expect = 7e-65, Method: Composition-based stats.
Identities = 47/189 (25%), Positives = 96/189 (51%), Gaps = 5/189 (3%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ GP G++ L ++L ++ +D ++ TTR R+ E G YHF+S + F+ I
Sbjct 6 LLISGPSGAGKSTLLKKLFDEFEDELYFSISSTTRKPREGEKNGIHYHFISHEEFQKGID 65
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-IFIAPP 600
+ F+E +N YGTS+ + +++GKI + + Q K R + +FI
Sbjct 66 SDHFLEWARVHENFYGTSLKHTQNALDNGKIVVFDIDVQGFKIARKKMADKIVSVFITTK 125
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI- 659
+++ L+ L K + + + + + EM++ +D I+N +L ++Y+ L ++
Sbjct 126 NKDELKKRLIKRNTDTIIQLEKRLQNASDEMKEL--SEYDYLIINDELKQSYEALRAILI 183
Query 660 -NKLDTEPQ 667
+K T+ Q
Sbjct 184 AHKFRTKGQ 192
>sp|Q9PNB8|KGUA_CAMJE Guanylate kinase OS=Campylobacter jejuni
subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
OX=192222 GN=gmk PE=3 SV=1
Length=207
Score = 216 bits (550), Expect = 7e-65, Method: Composition-based stats.
Identities = 47/189 (25%), Positives = 96/189 (51%), Gaps = 5/189 (3%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+++ GP G++ L ++L ++ +D ++ TTR R+ E G YHF+S + F+ I
Sbjct 8 LLISGPSGAGKSTLLKKLFDEFEDELYFSISSTTRKPREGEKNGIHYHFISHEEFQKGID 67
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI-IFIAPP 600
+ F+E +N YGTS+ + +++GKI + + Q K R + +FI
Sbjct 68 SDHFLEWARVHENFYGTSLKHTQNALDNGKIVVFDIDVQGFKIARKKMADKIVSVFITTK 127
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI- 659
+++ L+ L K + + + + + EM++ +D I+N +L ++Y+ L ++
Sbjct 128 NKDELKKRLIKRNTDTIIQLEKRLQNASDEMKEL--SEYDYLIINDELKQSYEALRAILI 185
Query 660 -NKLDTEPQ 667
+K T+ Q
Sbjct 186 AHKFRTKGQ 194
>sp|Q491W5|KGUA_BLOPB Guanylate kinase OS=Blochmannia pennsylvanicus
(strain BPEN) OX=291272 GN=gmk PE=3 SV=1
Length=212
Score = 216 bits (550), Expect = 8e-65, Method: Composition-based stats.
Identities = 44/196 (22%), Positives = 95/196 (48%), Gaps = 7/196 (4%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFAS--AVPHTTRSRRDQEVAGRDYHFVSRQ 534
N I+ P G++ L ++ + + + ++ +TTR +R E+ G+DY+F+S++
Sbjct 3 NSGILCIISAPSGTGKSTLIHTVIQCDCFVYQTKLSISYTTRIKRPGEIHGKDYYFISKK 62
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
F+ I F E+ + YGT+ + ++N+G +L++ + + +R+ K
Sbjct 63 KFKYMIDKNMFFEYAMIFNHYYGTAKTDIETMLNTGIHIVLNIDWKGAQQIRSKISKNIY 122
Query 595 -IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI PPS++ L L G++ + + + + E+ ++ +D I+N + + A
Sbjct 123 TIFILPPSKKELARRLYLRGEDTEKVIVARMGQAMDEI--SHFKEYDYIIINDNFNIALM 180
Query 654 ELLRLI--NKLDTEPQ 667
L ++ +L Q
Sbjct 181 HLQSIMLSEQLRIAHQ 196
>sp|Q8Y672|KGUA_LISMO Guanylate kinase OS=Listeria monocytogenes
serovar 1/2a (strain ATCC BAA-679 / EGD-e) OX=169963 GN=gmk
PE=1 SV=1
Length=205
Score = 216 bits (549), Expect = 8e-65, Method: Composition-based stats.
Identities = 44/166 (27%), Positives = 74/166 (45%), Gaps = 2/166 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
R I+L GP G+ +R+ + + F ++ TTR R+ E G DY+F SR+
Sbjct 2 TERGLLIVLSGPSGVGKGTVREAVFKDPETSFDYSISMTTRLPREGEQDGVDYYFRSREV 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I GK +E+ E+ N YGT ++ V + + +G L + Q +R + + I
Sbjct 62 FEQAIKDGKMLEYAEYVGNYYGTPLEYVEEKLAAGVDIFLEIEVQGAMQVRKAMPEGIFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDT 641
F+ PP L+ + G + +E+E +D
Sbjct 122 FLTPPDLSELKNRIIGRGTESMEVVEERMETAKKEIEMMAS--YDY 165
>sp|Q71YI9|KGUA_LISMF Guanylate kinase OS=Listeria monocytogenes
serotype 4b (strain F2365) OX=265669 GN=gmk PE=3 SV=1
Length=205
Score = 216 bits (549), Expect = 8e-65, Method: Composition-based stats.
Identities = 44/166 (27%), Positives = 74/166 (45%), Gaps = 2/166 (1%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
R I+L GP G+ +R+ + + F ++ TTR R+ E G DY+F SR+
Sbjct 2 TERGLLIVLSGPSGVGKGTVREAVFKDPETSFDYSISMTTRLPREGEQDGVDYYFRSREV 61
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
FE I GK +E+ E+ N YGT ++ V + + +G L + Q +R + + I
Sbjct 62 FEQAIKDGKMLEYAEYVGNYYGTPLEYVEEKLAAGVDIFLEIEVQGAMQVRKAMPEGIFI 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDT 641
F+ PP L+ + G + +E+E +D
Sbjct 122 FLTPPDLSELKNRIIGRGTESMEVVEERMETAKKEIEMMAS--YDY 165
>sp|O84033|KGUA_CHLTR Guanylate kinase OS=Chlamydia trachomatis
(strain D/UW-3/Cx) OX=272561 GN=gmk PE=3 SV=1
Length=205
Score = 215 bits (548), Expect = 1e-64, Method: Composition-based stats.
Identities = 57/182 (31%), Positives = 77/182 (42%), Gaps = 3/182 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ I+ P G+ L L + D F V TTRS R EV G DY FVS F+
Sbjct 17 FPKLFIISAPAGAGKTTLTHMLQREFPDAFEKTVSSTTRSARPGEVHGVDYLFVSEDDFK 76
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
+ F+E YGTS + +V+ GK C+ + Q L+ IFI
Sbjct 77 QSLDREDFLEWVFLFGTYYGTSKAEISRVLQKGKHCIAVIDVQGALALKKQMP-AVTIFI 135
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PSQE L L K + +E +E + +E FD +VN DL AYQ L
Sbjct 136 QAPSQEELERRLNARDSE-KDFQKKERLEHSA-VEIAAASEFDYVVVNDDLITAYQVLRS 193
Query 658 LI 659
+
Sbjct 194 IF 195
>sp|Q3KMZ2|KGUA_CHLTA Guanylate kinase OS=Chlamydia trachomatis
serovar A (strain ATCC VR-571B / DSM 19440 / HAR-13) OX=315277
GN=gmk PE=3 SV=1
Length=205
Score = 215 bits (548), Expect = 1e-64, Method: Composition-based stats.
Identities = 57/182 (31%), Positives = 77/182 (42%), Gaps = 3/182 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ I+ P G+ L L + D F V TTRS R EV G DY FVS F+
Sbjct 17 FPKLFIISAPAGAGKTTLTHMLQREFPDAFEKTVSSTTRSARPGEVHGVDYLFVSEDDFK 76
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
+ F+E YGTS + +V+ GK C+ + Q L+ IFI
Sbjct 77 QSLDREDFLEWVFLFGTYYGTSKAEISRVLQKGKHCIAVIDVQGALALKKQMP-AVTIFI 135
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PSQE L L K + +E +E + +E FD +VN DL AYQ L
Sbjct 136 QAPSQEELERRLNARDSE-KDFQKKERLEHSA-VEIAAASEFDYVVVNDDLITAYQVLRS 193
Query 658 LI 659
+
Sbjct 194 IF 195
>sp|Q7VIA1|KGUA_HELHP Guanylate kinase OS=Helicobacter hepaticus
(strain ATCC 51449 / 3B1) OX=235279 GN=gmk PE=3 SV=1
Length=200
Score = 214 bits (546), Expect = 2e-64, Method: Composition-based stats.
Identities = 51/188 (27%), Positives = 89/188 (47%), Gaps = 4/188 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
++ +I+ GP CG++ L + L+ + + ++ TTR R+ E G YHFVS++ F
Sbjct 2 SKGAVLIISGPSGCGKSTLTKSLIESIPNVY-FSISTTTRPMREGETDGVHYHFVSKEHF 60
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK-PYII 595
DI F+E E N YGTS+ V+Q + KI L + Q +++ +
Sbjct 61 LQDIHNNVFLEWAEVHTNFYGTSLKPVQQALEQDKIVLFDVDVQGHHSIKEYFGDFAKSV 120
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI +++ LR L + +I+ EM+ + H FD I+N D+ A + +
Sbjct 121 FITTKNKDILRERLISRQTDDLQTIEFRLIQAHNEMQ--HIHNFDYLIINDDITTAKEAM 178
Query 656 LRLINKLD 663
+ + L
Sbjct 179 VAIARSLK 186
>sp|Q2GHE0|KGUA_EHRCR Guanylate kinase OS=Ehrlichia chaffeensis
(strain ATCC CRL-10679 / Arkansas) OX=205920 GN=gmk PE=3 SV=1
Length=209
Score = 215 bits (547), Expect = 2e-64, Method: Composition-based stats.
Identities = 45/192 (23%), Positives = 83/192 (43%), Gaps = 4/192 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+R +++ P G+ + L+N+ ++ ++ TTR RD E+ G+DY FV+ F
Sbjct 7 SRGIMLVISSPSGGGKTTISHLLINELQNDLVRSISVTTREPRDGEINGKDYFFVTEPEF 66
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK-PYII 595
+ +E+ + N YG V I +G L S+ Q L + + I
Sbjct 67 INLCNTNQMLEYAKVFGNYYGIPRKFVTDNIANGVSVLFSIDWQGAFKLIDIMREHVVSI 126
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS E L+ L + + E E ++ + +D IVN D++++ ++
Sbjct 127 FILPPSMEELQRRLYNRSGES-DVINKRLGEAA--FEISHCYRYDYVIVNHDIEQSVYQI 183
Query 656 LRLINKLDTEPQ 667
+ + Q
Sbjct 184 KCIFTSEKLKTQ 195
>sp|Q6F1S1|KGUA_MESFL Guanylate kinase OS=Mesoplasma florum (strain
ATCC 33453 / NBRC 100688 / NCTC 11704 / L1) OX=265311
GN=gmk PE=3 SV=1
Length=297
Score = 218 bits (555), Expect = 2e-64, Method: Composition-based stats.
Identities = 46/190 (24%), Positives = 85/190 (45%), Gaps = 3/190 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
N+ + II+ GP G+ + L+ + + +V TTR+ R+ EV G +Y FVS++ F
Sbjct 3 NKGKVIIISGPSGVGKGSVNGELLTNKDLKLEYSVSMTTRAPREGEVNGVNYFFVSKEEF 62
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
I + IE+ F N YGT V + +N GK +L + + ++ IF
Sbjct 63 ANAIVNNELIEYANFVGNSYGTPRKYVEEKLNEGKNVILEIEVDGATQVLRNEENVLSIF 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+ PP+ L + + + + + +E H +D + N ++ A ++
Sbjct 123 LMPPTLNELESRIKGRATESDDKIKARLDKAL--LEIPLKHNYDYVVENDSVENAVSKIT 180
Query 657 RL-INKLDTE 665
+ I + TE
Sbjct 181 DILIREKCTE 190
>sp|Q9PQS9|KGUA_UREPA Guanylate kinase OS=Ureaplasma parvum serovar
3 (strain ATCC 700970) OX=273119 GN=gmk PE=3 SV=1
Length=191
Score = 214 bits (545), Expect = 2e-64, Method: Composition-based stats.
Identities = 50/184 (27%), Positives = 87/184 (47%), Gaps = 4/184 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R + I+ GP G++ + +++N++ A ++ TTR +R+ EV G DY+FV+ + F+
Sbjct 3 RGKLIVFSGPSGVGKHTILSKIINRKDLNLAYSISMTTRKKREGEVNGVDYYFVNDEEFK 62
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTL--RNSDLKPYII 595
I + IE EF N YGT V ++ + GK +L + + + I
Sbjct 63 KAILNNELIEWAEFVGNKYGTPRTIVEKLRDEGKNVILEIEVVGALKVLDLYKNDDLISI 122
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PPS + L+ L K + I + T E+ Y+ I+N + D A +L
Sbjct 123 FLLPPSIDELKKRLLKRNTETLETIKKRIQKATHEITIK--DYYQYNIINDNPDHAANQL 180
Query 656 LRLI 659
+I
Sbjct 181 AEII 184
>sp|Q9CCQ7|KGUA_MYCLE Guanylate kinase OS=Mycobacterium leprae
(strain TN) OX=272631 GN=gmk PE=3 SV=1
Length=210
Score = 214 bits (546), Expect = 3e-64, Method: Composition-based stats.
Identities = 55/190 (29%), Positives = 89/190 (47%), Gaps = 5/190 (3%)
Query 472 YHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFV 531
+ + ++ R ++L GP G++ + + L + +V TTR R E+ G DYHFV
Sbjct 16 WSEQTDKGRVVVLSGPSAVGKSTVVRCL-RERVSNLHFSVSATTREPRPDEMDGVDYHFV 74
Query 532 SRQAFEADIAAGKFIEHGEFEK--NLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD 589
S F+ I G +E E + GT + VR +G L+ + + ++ +
Sbjct 75 SPARFQQLIDQGALLEWAEIHGGMHRSGTLAEPVRVAAAAGFPVLIEVDLAGARAVKKAM 134
Query 590 LKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLD 649
+ +F+APPS E L A L G PE +R +E R +E FD +VN L+
Sbjct 135 PEAIAVFLAPPSWEDLEARLVGRGTET-PEAIRRRLETAR-IELAAQDDFDEVVVNRRLE 192
Query 650 KAYQELLRLI 659
A EL+ L+
Sbjct 193 SACAELVSLL 202
>sp|Q8RHI9|KGUA_FUSNN Guanylate kinase OS=Fusobacterium nucleatum
subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681
/ CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)
OX=190304 GN=gmk PE=3 SV=1
Length=185
Score = 213 bits (542), Expect = 4e-64, Method: Composition-based stats.
Identities = 40/182 (22%), Positives = 83/182 (46%), Gaps = 4/182 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
++ GP G++ + + + +E+ ++ T+R R+ E G DY F++ + FE
Sbjct 4 GALYVVSGPSGAGKSTVCK--LVRERLGINLSISATSRKPRNGEQEGVDYFFITAEEFER 61
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
I F+E+ N YGT V + + G+ LL + Q ++N + +IF
Sbjct 62 KIKNDDFLEYANVHGNYYGTLKSEVEERLKRGEKVLLEIDVQGGVQVKNKFPEANLIFFK 121
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
++E L L + + + +E+E +D I+N+++++A +L+ +
Sbjct 122 TANKEELEKRLRGRNTDSEEVIQARLKNSLKELE--YESKYDRVIINNEIEQACNDLISI 179
Query 659 IN 660
I
Sbjct 180 IE 181
>sp|Q9RS38|KGUA_DEIRA Guanylate kinase OS=Deinococcus radiodurans
(strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074
/ LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1) OX=243230
GN=gmk PE=3 SV=2
Length=239
Score = 215 bits (547), Expect = 4e-64, Method: Composition-based stats.
Identities = 58/201 (29%), Positives = 87/201 (43%), Gaps = 9/201 (4%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
P R I++ G G+ LR+R + + D F + TTR R EV GRDY FVS
Sbjct 15 PQGRGLLIVVTGASGVGKGTLRERWLAGQ-DVF-YSTSWTTREPRPGEVNGRDYVFVSPA 72
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD-LKPY 593
F A F+EH +F N YGT I+ + + G+ +L + + +++ +
Sbjct 73 EFLAKAQQNGFLEHAQFVGNHYGTPIEPIEAALERGQDVVLEIEVEGAMQVKDRMGEQAI 132
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
++FI PPS LR L + + E++ H F IVN +LD+A
Sbjct 133 LVFIMPPSLTELRRRLTGRATETPERIEKRLTRARDEIQ--AAHDFRYVIVNDNLDRAVS 190
Query 654 ELLRLIN----KLDTEPQWVP 670
ELL + W P
Sbjct 191 ELLAVQQAERAAQKAAEHWTP 211
>sp|Q0S0L7|KGUA_RHOJR Guanylate kinase OS=Rhodococcus jostii (strain
RHA1) OX=101510 GN=gmk PE=3 SV=1
Length=207
Score = 213 bits (543), Expect = 6e-64, Method: Composition-based stats.
Identities = 57/194 (29%), Positives = 90/194 (46%), Gaps = 5/194 (3%)
Query 468 EMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRD 527
++S R R ++L GP G++ + RL+ + +V TTR R EV G+D
Sbjct 6 QVSESKTAVRRGRLVVLAGPSAVGKSSVV-RLLRERMPELVFSVSATTRDPRPGEVDGKD 64
Query 528 YHFVSRQAFEADIAAGKFIEHGEFEK--NLYGTSIDSVRQVINSGKICLLSLRTQSLKTL 585
Y F SR F+ I +G+ +E E L GT VR+ I GK L+ + + +
Sbjct 65 YRFTSRDEFQRMIESGELLEWAEIHGGLQLSGTPAAPVRRAIEQGKPVLVEVDLAGARAV 124
Query 586 RNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVN 645
R + + ++F+APPS + L L G R + E+E FD IVN
Sbjct 125 RAAMPEALLVFMAPPSWDVLVERLTGRGTESAEVVERRLATARVELEAQ--DEFDEVIVN 182
Query 646 SDLDKAYQELLRLI 659
D+ ++ EL+ L+
Sbjct 183 EDVSRSCDELVSLL 196
>sp|Q822M8|KGUA_CHLCV Guanylate kinase OS=Chlamydia caviae (strain
ATCC VR-813 / DSM 19441 / 03DC25 / GPIC) OX=227941 GN=gmk
PE=3 SV=1
Length=204
Score = 212 bits (540), Expect = 2e-63, Method: Composition-based stats.
Identities = 50/186 (27%), Positives = 86/186 (46%), Gaps = 3/186 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
P+ + + P G+ L + L + D F + TTR+ R +EV+G DY FVS+
Sbjct 13 HPSCAPKLFTISAPAGAGKTTLVRMLAQEFPDSFQKTLSLTTRAPRPEEVSGIDYWFVSQ 72
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ F+ + + F+E YGTS + ++ SGK + + + +L++
Sbjct 73 EEFKQRLDSNNFLEWVLLFGEYYGTSRLEIDEIWKSGKHAVAVIDVEGALSLKSKIP-TV 131
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI+ PSQE L L G + + + +EQ + F+ I+N DL K+Y+
Sbjct 132 TIFISAPSQEELERRLKYRGSEQDSQRQERL--QHSLIEQAASNQFEYVIINDDLQKSYE 189
Query 654 ELLRLI 659
L +
Sbjct 190 ILKSIF 195
>sp|Q9PL09|KGUA_CHLMU Guanylate kinase OS=Chlamydia muridarum
(strain MoPn / Nigg) OX=243161 GN=gmk PE=3 SV=1
Length=205
Score = 212 bits (540), Expect = 2e-63, Method: Composition-based stats.
Identities = 51/181 (28%), Positives = 77/181 (43%), Gaps = 3/181 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+ + P G+ L L + F V TTRS R EV G DY F+S F+
Sbjct 18 PKLFTISAPAGAGKTTLVHMLQEEFPSAFEKTVSSTTRSPRPGEVHGVDYVFMSEDEFKD 77
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+ F+E YGTS + + +++ GK C+ + Q TL+ + IFI
Sbjct 78 VLDKDGFLEWVFLFGTYYGTSKEGISRILQKGKHCIAVIDVQGALTLKKQM-QTVAIFIQ 136
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PSQE L L + + + ++ + +E FD +VN DL AYQ L +
Sbjct 137 APSQEELERRLNTR--DSEKDLQKKERLEHSNVEIAAASQFDYVVVNDDLTTAYQVLRSI 194
Query 659 I 659
Sbjct 195 F 195
>sp|Q8G813|KGUA_BIFLO Guanylate kinase OS=Bifidobacterium longum
(strain NCC 2705) OX=206672 GN=gmk PE=3 SV=1
Length=196
Score = 211 bits (538), Expect = 2e-63, Method: Composition-based stats.
Identities = 56/191 (29%), Positives = 91/191 (48%), Gaps = 8/191 (4%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ R I+L GP G+ + +L + + +V TTR+ R EV G +Y F++
Sbjct 5 THAGRLIVLTGPTAVGKGTVEAKLRADHPEVW-VSVSATTRAPRPGEVDGVNYWFLTEDE 63
Query 536 FEADIAAGKFIEHGEFEK-NLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS----DL 590
F A AAG+F+E YGT + V + + +G +L + Q + ++ DL
Sbjct 64 FLAREAAGEFLETAVVHGMAHYGTLLKPVEEHLAAGVPTILEIDLQGARRVKQRAAELDL 123
Query 591 KPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDK 650
+ +FIAPPS E L L G ++ R + +T ++E FD IVN +D+
Sbjct 124 EVVYVFIAPPSFEELERRLIGRGTETAEQQARRL--ETAKVELAAESEFDVTIVNETVDQ 181
Query 651 AYQELLRLINK 661
A +L +I K
Sbjct 182 AAADLWSVIAK 192
>sp|Q2GD44|KGUA_NEOSM Guanylate kinase OS=Neorickettsia sennetsu
(strain ATCC VR-367 / Miyayama) OX=222891 GN=gmk PE=3 SV=1
Length=206
Score = 212 bits (539), Expect = 2e-63, Method: Composition-based stats.
Identities = 46/191 (24%), Positives = 82/191 (43%), Gaps = 4/191 (2%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ I+ P G+ + L+ ++ ++ TTR R +E G DY+FVS+ F
Sbjct 2 RKGILFIISSPSGGGKTTVADFLVGQD-LSIKRSISFTTRQPRGEEKDGIDYYFVSKDEF 60
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+ G+ +EH +N YGTS + + + G L + Q + +R IF
Sbjct 61 NRLLQEGEMLEHATVLQNQYGTSHRYIEETLALGIDVLCCIDWQGAEQIRKKT-NCISIF 119
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+ PPS ++L+ L G + + K E + +D +VN DL + Q++L
Sbjct 120 LLPPSLQKLKTRLTSRGTDTADVIEYRL--KVALEEIQHFSKYDYVLVNDDLTETKQKVL 177
Query 657 RLINKLDTEPQ 667
+I +
Sbjct 178 SIITAEREKLV 188
>sp|Q7UP92|KGUA_RHOBA Guanylate kinase OS=Rhodopirellula baltica
(strain DSM 10527 / NCIMB 13988 / SH1) OX=243090 GN=gmk PE=3
SV=1
Length=209
Score = 212 bits (539), Expect = 2e-63, Method: Composition-based stats.
Identities = 50/196 (26%), Positives = 84/196 (43%), Gaps = 5/196 (3%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ A+ R +I+ GP G++ + ++LM + +V TTR R E+ G+DY F+S
Sbjct 11 ETAHPGRLVIISGPSGAGKSTVVKQLMKRCDVPLQLSVSATTREPRPGEIHGQDYFFLSH 70
Query 534 QAFEADIAAGKFIEHGEFE--KNLYGTSIDSVRQVINSGKICLLSLRTQSL-KTLRNSDL 590
+ FE F+E + YGT D V +N+GK +L + Q L +
Sbjct 71 EEFERRRKLNDFVECKQVFSMGQWYGTLKDQVATGLNAGKWVILEIDVQGAMAVLDDPHY 130
Query 591 KPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDK 650
+P IF+ P S E L L G + + EM+ + I+N +D
Sbjct 131 RPVTIFVHPGSMEELERRLRNRGTESESSLTARLETAAAEMQ--CLSRYQYEIINESVDN 188
Query 651 AYQELLRLINKLDTEP 666
A E+ +++
Sbjct 189 AVTEICQILLDQRKTT 204
>sp|Q9Z961|KGUA_CHLPN Guanylate kinase OS=Chlamydia pneumoniae
OX=83558 GN=gmk PE=3 SV=1
Length=205
Score = 211 bits (538), Expect = 3e-63, Method: Composition-based stats.
Identities = 52/181 (29%), Positives = 83/181 (46%), Gaps = 3/181 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+ + P G+ L + L + FA + TTR R+ EV G+DYHFVS + F+
Sbjct 19 PKLFTISAPAGVGKTTLVRMLEQEFSSAFAETISVTTRKPREGEVPGKDYHFVSHEEFQR 78
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+ +E YGTS+ + ++ + GK + + Q +R+ IFIA
Sbjct 79 LLDRQALLEWVFLFGECYGTSMLEIERIWSLGKHAVAVIDIQGALFIRSRMP-SVSIFIA 137
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPSQE L LA G + + + +E + FD I+N DL++AY+ L +
Sbjct 138 PPSQEELERRLASRGSEEGSQRKERL--EHSLIELAAANQFDYVIINDDLNQAYRVLKSI 195
Query 659 I 659
Sbjct 196 F 196
>sp|Q2G9M5|KGUA_NOVAD Guanylate kinase OS=Novosphingobium aromaticivorans
(strain ATCC 700278 / DSM 12444 / CCUG 56034 / CIP
105152 / NBRC 16084 / F199) OX=279238 GN=gmk PE=3 SV=1
Length=221
Score = 212 bits (540), Expect = 3e-63, Method: Composition-based stats.
Identities = 44/161 (27%), Positives = 71/161 (44%), Gaps = 2/161 (1%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R IL P G+ + ++L++++ + A +V TTR R EV G+DY FV F
Sbjct 18 RRGLMFILSSPSGAGKTTIARKLLSEDSE-IAMSVSVTTRPMRPGEVDGKDYFFVEPAEF 76
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTL-RNSDLKPYII 595
E + A +F E N YGT +R+ + +G L + Q + L + + +
Sbjct 77 ERMVEANEFYEWATVFGNCYGTPKAHIRERLKTGGDVLFDIDWQGTQQLYQKAQADVVRV 136
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNG 636
FI PPS + LR L G + + E+ +G
Sbjct 137 FILPPSLDELRRRLTGRGTDSAEVIAARMDRAQAEISHWDG 177
>sp|Q2GLF7|KGUA_ANAPZ Guanylate kinase OS=Anaplasma phagocytophilum
(strain HZ) OX=212042 GN=gmk PE=1 SV=1
Length=210
Score = 212 bits (539), Expect = 3e-63, Method: Composition-based stats.
Identities = 49/189 (26%), Positives = 82/189 (43%), Gaps = 3/189 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
++L P CG+ + +L+ K+K+ +V TTR+ R E G+DY+FV R+ F
Sbjct 6 GVILVLSSPSGCGKTTVANKLLEKQKNNIVKSVSVTTRAARKGEKEGKDYYFVDREEFLR 65
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK-PYIIFI 597
+ G+ IEH E N YG ++ ++ G LL + Q + IFI
Sbjct 66 LCSNGEIIEHAEVFGNFYGVPRKNLEDNVDKGVSTLLVIDWQGAFKFMEMMREHVVSIFI 125
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS E LR L + + K E ++ +D IVN D+++ +
Sbjct 126 MPPSMEELRRRLCGRRADDSEVVEARL--KGAAFEISHCEAYDYVIVNEDIEETADRISN 183
Query 658 LINKLDTEP 666
++ +
Sbjct 184 ILRAEQMKT 192
>sp|P60550|KGUA_CORDI Guanylate kinase OS=Corynebacterium diphtheriae
(strain ATCC 700971 / NCTC 13129 / Biotype gravis) OX=257309
GN=gmk PE=3 SV=1
Length=191
Score = 211 bits (537), Expect = 3e-63, Method: Composition-based stats.
Identities = 51/183 (28%), Positives = 89/183 (49%), Gaps = 5/183 (3%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
R ++L GP G++ + RL + +D + +V TTR+ R E G DY FVS + F++
Sbjct 8 GRLVVLAGPSAVGKSTVVHRLREEIEDLY-FSVSMTTRAPRPGERDGVDYFFVSPEEFQS 66
Query 539 DIAAGKFIEHGEFEKNLY--GTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
I AG+ +E + L GT V + +G+ L+ + + + + + +F
Sbjct 67 KIDAGEMLEWADIHGGLQRSGTPAGPVEAALLAGRPVLVEVDLVGARNVASLKPESETVF 126
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+APPS E L L G P+ R + +T + E H F +VN D++KA ++
Sbjct 127 LAPPSWEVLVERLTGRGTEPEDVITRRL--ETAKNELTAQHEFKHVVVNEDVEKAVSDIK 184
Query 657 RLI 659
++
Sbjct 185 EIL 187
>sp|Q6AF82|KGUA_LEIXX Guanylate kinase OS=Leifsonia xyli subsp.
xyli (strain CTCB07) OX=281090 GN=gmk PE=3 SV=1
Length=254
Score = 213 bits (542), Expect = 3e-63, Method: Composition-based stats.
Identities = 52/180 (29%), Positives = 87/180 (48%), Gaps = 4/180 (2%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
++L GP G+ + + + +V TTRS R EV G +Y+FV AF+ I
Sbjct 66 LVVLAGPTAVGKGTVSAYIRENYPEVL-LSVSATTRSPRPGEVDGVNYYFVDDAAFDRMI 124
Query 541 AAGKFIEHGEFEKNL-YGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
AAG +EH YGT + + ++ G+ LL + Q + +R S + +IF+ P
Sbjct 125 AAGDLLEHATVHNAYRYGTPRAPIEKALDDGRSVLLEIDLQGARQVRASMPEARLIFLLP 184
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
P+ E L L G E+ R + +T ++E + FD +VN + A +E++ L+
Sbjct 185 PTWEELVRRLTGRGTEDAAEQQRRL--ETAKVELAAQNEFDHRVVNHTVADAAREVVDLM 242
>sp|Q1IW06|KGUA_DEIGD Guanylate kinase OS=Deinococcus geothermalis
(strain DSM 11300 / AG-3a) OX=319795 GN=gmk PE=3 SV=1
Length=242
Score = 212 bits (539), Expect = 8e-63, Method: Composition-based stats.
Identities = 52/202 (26%), Positives = 86/202 (43%), Gaps = 9/202 (4%)
Query 473 HQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVS 532
++R I++ G G+ LR+R + + D F + TTR R E G DY FV+
Sbjct 16 SSSSHRGLLIVMTGASGVGKGTLRERWLAGQ-DVF-YSTSWTTREARPGERDGVDYVFVT 73
Query 533 RQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD-LK 591
+ F + F+EH +F N YGT + + + G+ +L + + ++ +
Sbjct 74 PEVFLEKVRQNGFLEHAQFVGNHYGTPTEPIEAALARGQDVVLEIEVEGAMQVKERMGEE 133
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
++FI PPS LR L + + E+ H F IVN DLD+A
Sbjct 134 AVLVFIMPPSLTELRRRLTGRATETPERIEKRLQRARDEI--MAAHAFRYVIVNDDLDRA 191
Query 652 YQELLRLIN----KLDTEPQWV 669
+EL + + E +W
Sbjct 192 VRELQAVQRAEHARQRPETEWT 213
>sp|Q3YRE2|KGUA_EHRCJ Guanylate kinase OS=Ehrlichia canis (strain
Jake) OX=269484 GN=gmk PE=3 SV=1
Length=209
Score = 210 bits (535), Expect = 1e-62, Method: Composition-based stats.
Identities = 45/188 (24%), Positives = 84/188 (45%), Gaps = 4/188 (2%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
+++ P G+ + L+++ ++ +V TTR RD EV G+DY FV+ F
Sbjct 11 MLVISSPSGGGKTTISHLLIDELQNDLVRSVSVTTREPRDGEVNGKDYFFVTEHEFINLC 70
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK-PYIIFIAP 599
+ +E+ + N YG V I +G L S+ Q L + + +FI P
Sbjct 71 NTDQMLEYAKVFGNYYGIPRKFVMDNITTGVSVLFSIDWQGAFKLIDIMREHVVSVFILP 130
Query 600 PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
PS E LR L K + +++ + + E ++ + +D IVN D++++ ++ +
Sbjct 131 PSMEELRRRLYNRS--GKSDIVKKRLGEAA-FEIDHCYRYDYVIVNHDVEESVHQIKCIF 187
Query 660 NKLDTEPQ 667
Q
Sbjct 188 TSERLRVQ 195
>sp|Q3B204|KGUA_CHLL3 Guanylate kinase OS=Chlorobium luteolum
(strain DSM 273 / BCRC 81028 / 2530) OX=319225 GN=gmk PE=3 SV=1
Length=197
Score = 209 bits (533), Expect = 1e-62, Method: Composition-based stats.
Identities = 54/190 (28%), Positives = 93/190 (49%), Gaps = 4/190 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
R ++ P G++ + +R++ + +V TTR R+ EV G +YHF+S++ FE+
Sbjct 9 GRLVVFSAPSGTGKSTIARRVLERFPS-MRFSVSATTRPMREGEVDGVNYHFLSKEDFES 67
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK-PYIIFI 597
+I G FIEH F N YGT + R+ + G LL L + L+ ++F+
Sbjct 68 EIRNGGFIEHEFFFGNHYGTLLQKTREAMAQGTDLLLDLDVKGAMNLKKLFPDSSLLVFL 127
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
APPS + L+ L + EE ++ + +E FDT I+N L+ A + ++
Sbjct 128 APPSMDVLKERLQSR--KSEDEESLKLRLERARLELGFADRFDTVIINDTLEDAVEAVIL 185
Query 658 LINKLDTEPQ 667
I+ + Q
Sbjct 186 AISNFLSTKQ 195
>sp|P60553|KGUA_MYCPA Guanylate kinase OS=Mycolicibacterium paratuberculosis
(strain ATCC BAA-968 / K-10) OX=262316 GN=gmk
PE=3 SV=1
Length=223
Score = 210 bits (535), Expect = 1e-62, Method: Composition-based stats.
Identities = 56/188 (30%), Positives = 88/188 (47%), Gaps = 5/188 (3%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+P+ R ++L GP G++ + + L + + +V TTR+ R EV G DYHFVS
Sbjct 16 EPSGDGRVVVLSGPSAVGKSTVVRCLRERVPN-LHFSVSATTRAPRPGEVDGVDYHFVSP 74
Query 534 QAFEADIAAGKFIEHGEFEK--NLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK 591
F+ I G +E E + GT VR + G L+ + + ++ + +
Sbjct 75 ARFQQLIDEGALLEWAEIHSGLHRSGTLAAPVRAAVARGCPVLIEVDLAGARAVKKAMPE 134
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
+F+APPS E L A L G R + +T +E H FD +VNS L+ A
Sbjct 135 ALTVFLAPPSWEDLEARLIGRGTETPEVIARRL--QTARVEMAAQHDFDRVVVNSRLESA 192
Query 652 YQELLRLI 659
EL+ L+
Sbjct 193 CAELVSLL 200
>sp|Q6A8H6|KGUA_CUTAK Guanylate kinase OS=Cutibacterium acnes
(strain DSM 16379 / KPA171202) OX=267747 GN=gmk PE=3 SV=1
Length=199
Score = 209 bits (533), Expect = 1e-62, Method: Composition-based stats.
Identities = 43/179 (24%), Positives = 79/179 (44%), Gaps = 4/179 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
++ GP G+ + L+ + + TTR R E G DY F++ + F+ +
Sbjct 23 VVSGPTAVGKGTVVGALLRSHPE-IVVSRSVTTRPPRPTERDGIDYDFITPEQFDKLVDG 81
Query 543 GKFIEHGEFEK-NLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+E + YGT V + + + +L + Q + +R + + IF+APPS
Sbjct 82 EGLLEWATVHNSHRYGTPRGPVERAVADNRTVVLEIDLQGARQVRETYPQATQIFLAPPS 141
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
E L L G ++ + + +T ++E N FD +VN +D A L+ L++
Sbjct 142 WEELVHRLIGRGTETPEQQKQRL--ETAKVELANADEFDAVVVNDTVDHAVAHLVELLS 198
>sp|Q3AQL3|KGUA_CHLCH Guanylate kinase OS=Chlorobium chlorochromatii
(strain CaD3) OX=340177 GN=gmk PE=3 SV=1
Length=190
Score = 208 bits (530), Expect = 3e-62, Method: Composition-based stats.
Identities = 57/182 (31%), Positives = 89/182 (49%), Gaps = 4/182 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+ I+ P G+ + ++ + + + +V TTR +R+ E G +Y+F+ + FE
Sbjct 7 GKLIVFSAPSGAGKTTIATMVLQRIAN-LSFSVSATTRKQREGEQDGVNYYFLDKATFEK 65
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK-PYIIFI 597
I G FIEH F N YGT +D+ V+ SGK LL + + +R + +IFI
Sbjct 66 KIEQGGFIEHEFFFGNYYGTLLDATESVLASGKNLLLDVDVKGALNVRKLFGERSLLIFI 125
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS E L L G L+E +E+ R E + FDT IVN++L A ++
Sbjct 126 QPPSMEVLIERLQGRGSEDDAA-LQERLERAR-FEMSFADQFDTIIVNNNLTAAVDDVEA 183
Query 658 LI 659
I
Sbjct 184 AI 185
>sp|Q8NQ42|KGUA_CORGL Guanylate kinase OS=Corynebacterium glutamicum
(strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318
/ LMG 3730 / NCIMB 10025) OX=196627 GN=gmk PE=3 SV=2
Length=190
Score = 208 bits (529), Expect = 3e-62, Method: Composition-based stats.
Identities = 50/183 (27%), Positives = 82/183 (45%), Gaps = 5/183 (3%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
R +IL GP G++ + RL N + + +V TTR+ R EV GRDY +V+ Q F+
Sbjct 8 GRLVILAGPSAVGKSTVVDRLRNDVPNLY-FSVSMTTRAPRPGEVDGRDYFYVTAQEFQD 66
Query 539 DIAAGKFIEHGEFEKNLY--GTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
I G+ +E + L GT V + +G+ L+ + + + + IF
Sbjct 67 KIDCGEMLEWADIHGGLQRSGTPAGPVNEARQNGRPVLVEVDLAGARNIASLIPDAETIF 126
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+APPS E L L G + R + E+ F I+N D+D A + +
Sbjct 127 LAPPSWEVLVERLTGRGTESEDVIARRLETAREEL--AAQSEFKHVIINDDVDTAVKAIE 184
Query 657 RLI 659
++
Sbjct 185 DVL 187
>sp|Q5L5M1|KGUA_CHLAB Guanylate kinase OS=Chlamydia abortus (strain
DSM 27085 / S26/3) OX=218497 GN=gmk PE=3 SV=1
Length=204
Score = 208 bits (530), Expect = 5e-62, Method: Composition-based stats.
Identities = 48/186 (26%), Positives = 83/186 (45%), Gaps = 3/186 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
P + + P G+ L + L + D F + TTR+ R +E+ G DY FVS+
Sbjct 13 HPLCAPKLFTISAPAGAGKTTLVRMLAREFPDSFQKTLSLTTRAPRPEEIPGVDYQFVSQ 72
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ F+ + F+E YGTS + ++ SG+ + + + L++
Sbjct 73 EEFQRRLDNEDFLEWVALFGEYYGTSRLGIDEIWKSGRHAVAVIDVEGALVLQSKIP-TV 131
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI+ PSQE L L + G + + + +EQ F+ I+N DL+K+Y+
Sbjct 132 AIFISAPSQEELERRLKQRGSEQDTQRQERL--QHSLIEQAAADKFEYVIINDDLEKSYE 189
Query 654 ELLRLI 659
L +
Sbjct 190 VLKSIF 195
>sp|Q8KPQ7|KGUA_SYNE7 Guanylate kinase OS=Synechococcus elongatus
(strain ATCC 33912 / PCC 7942 / FACHB-805) OX=1140 GN=gmk
PE=3 SV=2
Length=183
Score = 207 bits (527), Expect = 6e-62, Method: Composition-based stats.
Identities = 51/181 (28%), Positives = 89/181 (49%), Gaps = 3/181 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
R ++L GP G+ L + ++++ + F ++ TTRS R EV G+ Y+F+SR+ F+
Sbjct 4 GRVVVLTGPSGVGKGTLLKAILSQHPEAF-LSISATTRSPRPGEVDGQHYYFLSREEFQT 62
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
IA +F+E EF NLYGT V + +N G+ +L + + + +R + + +
Sbjct 63 KIAEQEFLEWAEFAGNLYGTPRSPVIEQVNLGRTVILEIELEGARQVRKTLPSARQVMLL 122
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PPS E L + + + R +++ E+ FD ++N LD A L
Sbjct 123 PPSVEELERRIRERATEDEAAIARRLLQAQTEI--GAAKEFDRCVINDQLDTAITALEAA 180
Query 659 I 659
I
Sbjct 181 I 181
>sp|Q8A677|KGUA_BACTN Guanylate kinase OS=Bacteroides thetaiotaomicron
(strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774
/ NCTC 10582 / VPI-5482 / E50) OX=226186 GN=gmk PE=3 SV=1
Length=204
Score = 208 bits (529), Expect = 7e-62, Method: Composition-based stats.
Identities = 48/189 (25%), Positives = 79/189 (42%), Gaps = 5/189 (3%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+ II P G++ + L+ + A ++ T+R R E G +Y F++ + F
Sbjct 18 GKLIIFSAPSGSGKSTIINYLLTQN-LNLAFSISATSRPPRGTEKHGVEYFFLTPEEFRC 76
Query 539 DIAAGKFIEHGEFE-KNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK-PYIIF 596
I +F+E+ E YGT + V + + G+ + L ++ + IF
Sbjct 77 RIENNEFLEYEEVYKDRYYGTLKEQVEKQLEKGQNVVFDLDVVGGCNIKKYYGERALSIF 136
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+ PPS E LR L G + I + E E FD IVN DL+ A E L
Sbjct 137 VQPPSIEELRCRLTGRGTDEPEVIECRIAKA--EYEMTFAPQFDRVIVNDDLEAAKAETL 194
Query 657 RLINKLDTE 665
+I + +
Sbjct 195 EVIKEFLNK 203
>sp|Q8FT45|KGUA_COREF Guanylate kinase OS=Corynebacterium efficiens
(strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC
100395) OX=196164 GN=gmk PE=3 SV=1
Length=190
Score = 206 bits (525), Expect = 2e-61, Method: Composition-based stats.
Identities = 51/183 (28%), Positives = 81/183 (44%), Gaps = 5/183 (3%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
R +IL GP G++ + RL + + + +V TTR R EV GRDY +V+ Q F+
Sbjct 8 GRLVILAGPSAVGKSTVVDRLRSDVPNLY-FSVSMTTRDPRPGEVDGRDYFYVTAQEFQE 66
Query 539 DIAAGKFIEHGEFEKNLY--GTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
I G+ +E + L GT + VRQ G+ L+ + + + + IF
Sbjct 67 KIDRGEMLEWADIHGGLQRSGTPAEPVRQAREEGRPVLVEVDLVGARNIARLIPEAETIF 126
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+APPS E L L G + R + E+ F I+N D+D A +
Sbjct 127 LAPPSWEVLVERLTGRGTESQDVINRRLETAREEL--AAQSEFKHVIINDDVDTAVSAIK 184
Query 657 RLI 659
++
Sbjct 185 AVL 187
>sp|Q7MWS7|KGUA_PORGI Guanylate kinase OS=Porphyromonas gingivalis
(strain ATCC BAA-308 / W83) OX=242619 GN=gmk PE=3 SV=1
Length=188
Score = 206 bits (524), Expect = 2e-61, Method: Composition-based stats.
Identities = 48/185 (26%), Positives = 87/185 (47%), Gaps = 4/185 (2%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
+ II+ P G++ + +RL+ + ++ T+R+ R +E GR+Y+F+S + F
Sbjct 3 KLIIISAPSGTGKSTVIERLLTDRELNLHFSISATSRAPRGEEQNGREYYFLSPEEFRRR 62
Query 540 IAAGKFIEHGEFE-KNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK-PYIIFI 597
I A +F+E+ E YGT V +++ K + + ++++ IFI
Sbjct 63 IEANEFVEYEEVYRDKYYGTLKSEVERILKEEKNVIFDVDVVGAQSIKKYYGDRALAIFI 122
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS E LR+ L K G + + + + E E H FD VN DL +++ +
Sbjct 123 LPPSIEELRSRLQKRGTDSMETIKQRVDKA--EKEIGYAHLFDLRFVNDDLVTCVEQIRK 180
Query 658 LINKL 662
I +
Sbjct 181 AIAQF 185
>sp|Q30PL1|KGUA_SULDN Guanylate kinase OS=Sulfurimonas denitrificans
(strain ATCC 33889 / DSM 1251) OX=326298 GN=gmk PE=3
SV=1
Length=206
Score = 206 bits (524), Expect = 3e-61, Method: Composition-based stats.
Identities = 52/186 (28%), Positives = 88/186 (47%), Gaps = 4/186 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
++L GP G++ L + +++ + + ++ TTR R+ EV G YHFVS F+
Sbjct 6 GAILVLSGPSGAGKSSLIKEVIDDIGECY-FSISTTTRPIREGEVDGVHYHFVSESEFKK 64
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS-LKTLRNSDLKPYIIFI 597
DI F+E+ N YGTSI V++ + SGK+ + + Q + +FI
Sbjct 65 DIEDEFFLEYAVVHSNYYGTSIKPVKKALKSGKLVIFDIDVQGNATIINRLGDITTSVFI 124
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
+PP+ L+ L + K R I REM++ +D IVN +L +A + L
Sbjct 125 SPPTLSELKKRLEARSTDTKDVIERRIEMAKREMQR--VSEYDFLIVNDNLQEAAKTLRI 182
Query 658 LINKLD 663
+ +
Sbjct 183 IADAAR 188
>sp|Q4FMR1|KGUA_PELUB Guanylate kinase OS=Pelagibacter ubique
(strain HTCC1062) OX=335992 GN=gmk PE=3 SV=1
Length=210
Score = 206 bits (524), Expect = 4e-61, Method: Composition-based stats.
Identities = 56/184 (30%), Positives = 98/184 (53%), Gaps = 10/184 (5%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
+IL P G+ L +L++K K+ F ++ HTTR R E+A +DY+FV FE I
Sbjct 9 MVILSSPSGAGKTTLV-KLLSKNKN-FHISISHTTRKPRLNEIADKDYYFVDHDKFENLI 66
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII--FIA 598
+F+E+ + +LYGT+ V + + G+ + + Q ++N L +I FI
Sbjct 67 KNEEFLEYAKVFNHLYGTTRTPVIEKLEKGENVIFDIDWQGADQIKNKKLNYKLITFFIL 126
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHY--FDTAIVNSDLDKAYQELL 656
PPS+E L L+ + K + + E E+ +E ++ H+ +D I+N DL++ Y ++
Sbjct 127 PPSKEILFERLSNR--DMKDKLIVE--ERMKEFSRDVLHWINYDYVIINDDLEECYSKIS 182
Query 657 RLIN 660
LI+
Sbjct 183 SLID 186
>sp|Q46GV6|KGUA_PROMT Guanylate kinase OS=Prochlorococcus marinus
(strain NATL2A) OX=59920 GN=gmk PE=3 SV=1
Length=186
Score = 205 bits (522), Expect = 4e-61, Method: Composition-based stats.
Identities = 45/178 (25%), Positives = 81/178 (46%), Gaps = 3/178 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+L GP G+ + ++++ D + ++ TTR R E+ G Y F+ ++ F+
Sbjct 5 GNLTVLTGPSGVGKGTIVRKILESHSDVW-LSISATTRQPRSGEIDGEHYFFLEKKQFQE 63
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
I F+E F N YGT V++ I G LL + + + +R S + + IF+A
Sbjct 64 IIDKDGFLEWASFSNNFYGTPKKIVKEKIEKGTNVLLEIELEGARQIRKSFPEAFQIFLA 123
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
PP+ L + G + + E E FD ++N D++KA++E+
Sbjct 124 PPNLYELEKRIRGRGTETEESIRDRL--SIAEKELIAQKEFDAVVINEDIEKAFKEIE 179
>sp|Q8KFS5|KGUA_CHLTE Guanylate kinase OS=Chlorobaculum tepidum
(strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS) OX=194439
GN=gmk PE=3 SV=1
Length=195
Score = 205 bits (522), Expect = 6e-61, Method: Composition-based stats.
Identities = 59/194 (30%), Positives = 89/194 (46%), Gaps = 4/194 (2%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
Q ++ R I+ P G++ + +L+ + +V TTR R E G DYHF+SR
Sbjct 5 QVLDQGRLIVFSAPSGTGKSTVA-KLVMERLGSLEFSVSATTRQMRAGERDGVDYHFLSR 63
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD-LKP 592
+ FE IA FIEH F N YGT +D I +G L L + L+ +
Sbjct 64 EEFEKKIAENGFIEHEFFFGNFYGTLLDKTIDAIKAGHNLLFDLDVKGALNLKRIFGDQA 123
Query 593 YIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAY 652
++F+ PPS E L L E L+ +E+ EME ++ FD +VN DL +
Sbjct 124 LLVFLKPPSMEELARRLQARDSES-AEALKSRLERA-EMELSHAGEFDFVVVNDDLGRTV 181
Query 653 QELLRLINKLDTEP 666
+ I + +P
Sbjct 182 DAVATRIAEFLPQP 195
>sp|Q6MU25|KGUA_MYCMS Guanylate kinase OS=Mycoplasma mycoides
subsp. mycoides SC (strain PG1) OX=272632 GN=gmk PE=3 SV=1
Length=297
Score = 207 bits (528), Expect = 2e-60, Method: Composition-based stats.
Identities = 42/183 (23%), Positives = 75/183 (41%), Gaps = 2/183 (1%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ + II+ GP G+ + L+ +V TTR R+ EV G +Y FVS + F
Sbjct 3 KGKMIIISGPSGVGKGSVNGELLQNPDLHLRYSVSMTTRKPRNGEVDGVNYFFVSNEEFA 62
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I + IE+ F N YGT V Q + G +L + + N + IF+
Sbjct 63 KAIVNDELIEYAHFVGNSYGTPRKYVEQELKKGNNVILEIEVDGATQVLNKEPNVLSIFL 122
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PP+ L + + + + + +E H + I N ++ A ++
Sbjct 123 MPPNPTELANRIRGRQTEDEEKIKARLDKAL--LEIPLKHNYQYVIENDNVPNAVAKITD 180
Query 658 LIN 660
+++
Sbjct 181 VLH 183
>sp|Q3ZWD8|KGUA_DEHMC Guanylate kinase OS=Dehalococcoides mccartyi
(strain CBDB1) OX=255470 GN=gmk PE=3 SV=1
Length=206
Score = 204 bits (519), Expect = 2e-60, Method: Composition-based stats.
Identities = 48/199 (24%), Positives = 86/199 (43%), Gaps = 7/199 (4%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
+ +I+ GP G++ + R M + K V TTR +R+ E G DY+F+
Sbjct 9 KTEKPLLLIVSGPSGVGKDAVLAR-MKERKLPLTYIVTTTTRPKRETETEGVDYNFIRPA 67
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
F+ I+ + +E N YG +RQ ++ G ++ + Q +++
Sbjct 68 EFQELISQNELLEWANVYGNFYGVPKAPIRQALSRGSDVIVKVDVQGAASIKKIVPNAVF 127
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVN--SDLDKAY 652
IF+ PP + L L PE LR + T +E FD +VN ++D A
Sbjct 128 IFLMPPDMDELTRRLEHRLTES-PESLRRRL-ATAPLEIEKLPDFDYVVVNPEGEIDNAV 185
Query 653 QELLRLI--NKLDTEPQWV 669
+E++ +I +P+ +
Sbjct 186 REIMSIIAAEHCRIQPRLI 204
>sp|Q2SSR8|KGUA_MYCCT Guanylate kinase OS=Mycoplasma capricolum
subsp. capricolum (strain California kid / ATCC 27343 / NCTC
10154) OX=340047 GN=gmk PE=3 SV=1
Length=297
Score = 207 bits (526), Expect = 3e-60, Method: Composition-based stats.
Identities = 42/183 (23%), Positives = 76/183 (42%), Gaps = 2/183 (1%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ + II+ GP G+ + L+ R +V TTR R+ E+ G +Y FVS + F
Sbjct 3 KGKMIIISGPSGVGKGSVNGELLQNPDLRLKYSVSMTTRKPRNGEINGVNYFFVSNEEFA 62
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I + IE+ F N YGT V Q + G +L + + N + IF+
Sbjct 63 KAIVNDELIEYAHFVGNSYGTPRKYVEQELKKGNNVILEIEVDGATQVLNKEANVLSIFL 122
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PP+ L + + + + + +E H + I N ++ A ++
Sbjct 123 MPPNLTELANRIRGRQTEDEEKIKARLDKAL--LEIPLKHNYQYVIENDNVANAVAKITD 180
Query 658 LIN 660
+++
Sbjct 181 VLH 183
>sp|Q5HAK7|KGUA_EHRRW Guanylate kinase OS=Ehrlichia ruminantium
(strain Welgevonden) OX=254945 GN=gmk PE=3 SV=1
Length=209
Score = 203 bits (517), Expect = 3e-60, Method: Composition-based stats.
Identities = 48/191 (25%), Positives = 87/191 (46%), Gaps = 6/191 (3%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+R +++ P G+ + Q L+N+ + +V TTR R++EV G+DY FV+ F
Sbjct 7 SRGIMLVMSSPSGGGKTTISQLLVNELQGEIIRSVSVTTREPRNEEVEGKDYFFVTEDEF 66
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK-PYII 595
+ +E+ + N YG V IN+G L S+ Q L + + +
Sbjct 67 HHLCNTNQMLEYAKVFGNYYGIPRRFVMDNINNGISILFSIDWQGAFKLIDIMSEHVVSV 126
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS E L+ L + + E E ++ + ++ IVN +++++ Q++
Sbjct 127 FILPPSMEELKRRLYNRSGES-DMINQRLKEAA--FEISHCYRYNYIIVNHNIEESVQQI 183
Query 656 LRLI--NKLDT 664
+ KL T
Sbjct 184 KSIFIAEKLKT 194
>sp|Q5FFZ9|KGUA_EHRRG Guanylate kinase OS=Ehrlichia ruminantium
(strain Gardel) OX=302409 GN=gmk PE=3 SV=1
Length=209
Score = 203 bits (517), Expect = 3e-60, Method: Composition-based stats.
Identities = 48/191 (25%), Positives = 87/191 (46%), Gaps = 6/191 (3%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+R +++ P G+ + Q L+N+ + +V TTR R++EV G+DY FV+ F
Sbjct 7 SRGIMLVMSSPSGGGKTTISQLLVNELQGEIIRSVSVTTREPRNEEVEGKDYFFVTEDEF 66
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK-PYII 595
+ +E+ + N YG V IN+G L S+ Q L + + +
Sbjct 67 HHLCNTNQMLEYAKVFGNYYGIPRRFVMDNINNGISILFSIDWQGAFKLIDIMSEHVVSV 126
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
FI PPS E L+ L + + E E ++ + ++ IVN +++++ Q++
Sbjct 127 FILPPSMEELKRRLYNRSGES-DMINQRLKEAA--FEISHCYRYNYIIVNHNIEESVQQI 183
Query 656 LRLI--NKLDT 664
+ KL T
Sbjct 184 KSIFIAEKLKT 194
>sp|Q2LQ62|KGUA_SYNAS Guanylate kinase OS=Syntrophus aciditrophicus
(strain SB) OX=56780 GN=gmk PE=3 SV=1
Length=207
Score = 199 bits (506), Expect = 1e-58, Method: Composition-based stats.
Identities = 58/198 (29%), Positives = 93/198 (47%), Gaps = 5/198 (3%)
Query 469 MSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDY 528
M+ Q A R I+L G+ +R+ + + + +V +TTR+ R EV G+DY
Sbjct 1 MNKAGQEA-RGFFIVLSAASGTGKTSIRRIFLERCPE-VQFSVSYTTRTARPGEVDGQDY 58
Query 529 HFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS 588
FV+ F I G+F E E YGTS + +V+ G+ +L + + KTL+ +
Sbjct 59 FFVTETDFRERIDQGEFAEWEENYGRYYGTSGKVMTRVLEQGRDMILDIEPRGAKTLKKN 118
Query 589 DLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDL 648
+F+ PPS L+A L K G + E R+ ++K RE E +D I N L
Sbjct 119 YQGGIYVFVLPPSLAELKARLRKRG-ESEAEI-RKRLDKVRE-EIAEARGYDYVIFNDSL 175
Query 649 DKAYQELLRLINKLDTEP 666
+KA + L + +
Sbjct 176 EKAVERLQVIYQAEKSRA 193
>sp|P60549|KGUA_BDEBA Guanylate kinase OS=Bdellovibrio bacteriovorus
(strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100)
OX=264462 GN=gmk PE=3 SV=1
Length=185
Score = 197 bits (500), Expect = 5e-58, Method: Composition-based stats.
Identities = 53/185 (29%), Positives = 82/185 (44%), Gaps = 3/185 (2%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ R II+ P G++ +R+ ++ R V TTRS R E G Y+F+ FE
Sbjct 2 KTRMIIVAAPSGAGKSSFVERITRED-SRLVDIVTFTTRSIRQGETPGLQYNFIDHADFE 60
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
I G F+E + N YGTS S+ N GK ++ + Q + T ++ +FI
Sbjct 61 QKIKEGFFVEWAKVHTNFYGTSYSSLETAWNQGKTAIMDIDIQGVATFKSKFPDAKTVFI 120
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLR 657
PPS + LR + K + + E E FD IVN +K+Y E +
Sbjct 121 HPPSIDELRRRIEKRDGKVPADIEVRM--ANAEKEIREASKFDYQIVNDVFEKSYGEFKK 178
Query 658 LINKL 662
++ L
Sbjct 179 IVEDL 183
>sp|Q98PN5|KGUA_MYCPU Guanylate kinase OS=Mycoplasmopsis pulmonis
(strain UAB CTIP) OX=272635 GN=gmk PE=3 SV=1
Length=196
Score = 197 bits (501), Expect = 6e-58, Method: Composition-based stats.
Identities = 48/190 (25%), Positives = 94/190 (49%), Gaps = 7/190 (4%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+++ ++L+GP G+ + + L + + + + TTR +R+ E+ G Y F+S++ F
Sbjct 5 HKRNIVLLVGPSGVGKGTIEKILFESKTLKLSLSRSATTRKKREGEINGIHYFFISKEEF 64
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTL-----RNSDLK 591
E+ I +F+E E N YGT + + + + G+I +L + T K + D
Sbjct 65 ESKIENDEFMEWNEHFDNYYGTLLSEILLIFSQGRIPVLEVETYGAKKILQKYKDKKDFN 124
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
IF+ PPS E L + K G + K + + + E++ + F+ I N ++A
Sbjct 125 WITIFVDPPSFEELENRIIKRGTDTKEKIAIRMAKAKEELK--DRDLFEFKITNHTPEQA 182
Query 652 YQELLRLINK 661
+E+ ++I K
Sbjct 183 AEEIEKIILK 192
>sp|Q83GE3|KGUA_TROWT Guanylate kinase OS=Tropheryma whipplei
(strain Twist) OX=203267 GN=gmk PE=3 SV=2
Length=193
Score = 195 bits (496), Expect = 2e-57, Method: Composition-based stats.
Identities = 44/181 (24%), Positives = 86/181 (48%), Gaps = 4/181 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I+ GP G+ + L + ++ TTR RD E G DY+FV+ + F+ + +
Sbjct 16 IVAGPTAVGKGTVISHLRKCHP-QVKVSISATTREPRDSERDGIDYYFVTDEVFDCMVRS 74
Query 543 GKFIEHGEFEK-NLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+ +E + YGT + V +++++G+ +L + Q ++ +R + + PP+
Sbjct 75 GQMLEWATVHGLHKYGTPKEEVERLLHTGQPVILEIDLQGMRKVRKILPAVRTVILLPPA 134
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINK 661
+ L + + G + E + T + E FD IVN+D++ A EL +N+
Sbjct 135 WDDLICRIKRRGSESQDEIDARL--ATAKKELEAIGEFDYKIVNADVEIAANELWLAMNR 192
Query 662 L 662
+
Sbjct 193 V 193
>sp|Q83HT8|KGUA_TROW8 Guanylate kinase OS=Tropheryma whipplei
(strain TW08/27) OX=218496 GN=gmk PE=3 SV=1
Length=193
Score = 195 bits (496), Expect = 2e-57, Method: Composition-based stats.
Identities = 44/181 (24%), Positives = 86/181 (48%), Gaps = 4/181 (2%)
Query 483 ILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
I+ GP G+ + L + ++ TTR RD E G DY+FV+ + F+ + +
Sbjct 16 IVAGPTAVGKGTVISHLRKCHP-QVKVSISATTREPRDSERDGIDYYFVTDEVFDCMVRS 74
Query 543 GKFIEHGEFEK-NLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
G+ +E + YGT + V +++++G+ +L + Q ++ +R + + PP+
Sbjct 75 GQMLEWATVHGLHKYGTPKEEVERLLHTGQPVILEIDLQGMRKVRKILPAVRTVILLPPA 134
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINK 661
+ L + + G + E + T + E FD IVN+D++ A EL +N+
Sbjct 135 WDDLICRIKRRGSESQDEIDARL--ATAKKELEAIGEFDYKIVNADVEIAANELWLAMNR 192
Query 662 L 662
+
Sbjct 193 V 193
>sp|Q3ZAF9|KGUA_DEHM1 Guanylate kinase OS=Dehalococcoides mccartyi
(strain ATCC BAA-2266 / KCTC 15142 / 195) OX=243164 GN=gmk
PE=3 SV=1
Length=206
Score = 194 bits (493), Expect = 1e-56, Method: Composition-based stats.
Identities = 46/188 (24%), Positives = 82/188 (44%), Gaps = 5/188 (3%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
AN+ +++ GP G++ + R M + K A V TTR++R++E G DY+F+
Sbjct 9 KANKPLLLVVSGPSGVGKDAVLAR-MKERKLPLAYIVTTTTRTKREKETEGVDYNFIRPA 67
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
F+ I + +E N YG +RQ + G ++ + Q +++
Sbjct 68 EFQQLIGQNELLEWANVYGNFYGVPKAPIRQALAHGFDVIVKVDVQGAASIKKIVPNAVF 127
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVN--SDLDKAY 652
IF+ PP + L L R + T +E FD +VN ++D A
Sbjct 128 IFLMPPDMDELTRRLEHRLTESPESLKRRL--ATAPLEIEKLPDFDYVVVNPEGEIDNAV 185
Query 653 QELLRLIN 660
E++ +I+
Sbjct 186 SEIMSIIS 193
>sp|Q4AAI1|KGUA_MESHJ Guanylate kinase OS=Mesomycoplasma hyopneumoniae
(strain J / ATCC 25934 / NCTC 10110) OX=262719 GN=gmk
PE=3 SV=1
Length=197
Score = 191 bits (485), Expect = 1e-55, Method: Composition-based stats.
Identities = 48/188 (26%), Positives = 85/188 (45%), Gaps = 8/188 (4%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
+ IIL GP G+ + L+ + A+ TTR +R E+ G +Y F++ Q F+
Sbjct 7 KLIILSGPSGVGKGTIESLLLKNKNLLIKLAISATTREKRRDEINGVNYFFLTVQEFKEK 66
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKP------Y 593
I +FIE N YGT ++ + + I LL + T K + +
Sbjct 67 IENDEFIEWSCHFNNYYGTLKSQIKFIQSQNFIPLLEIDTTGAKNIIENYKNKGELSQLL 126
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI PPS E L+ + K + + + + E++ N F +VN +L++
Sbjct 127 TIFILPPSIESLKNRIQKRLTETNIQINQRLEKAKAEIKIKN--LFKFQVVNDNLEECVA 184
Query 654 ELLRLINK 661
++ ++I+K
Sbjct 185 QIEKIISK 192
>sp|Q601H3|KGUA_MESH2 Guanylate kinase OS=Mesomycoplasma hyopneumoniae
(strain 232) OX=295358 GN=gmk PE=3 SV=1
Length=197
Score = 191 bits (485), Expect = 1e-55, Method: Composition-based stats.
Identities = 48/188 (26%), Positives = 85/188 (45%), Gaps = 8/188 (4%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
+ IIL GP G+ + L+ + A+ TTR +R E+ G +Y F++ Q F+
Sbjct 7 KLIILSGPSGVGKGTIESLLLKNKNLLIKLAISATTREKRRDEINGVNYFFLTVQEFKEK 66
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKP------Y 593
I +FIE N YGT ++ + + I LL + T K + +
Sbjct 67 IENDEFIEWSCHFNNYYGTLKSQIKFIQSQNFIPLLEIDTTGAKNIIENYKNKGELSQLL 126
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI PPS E L+ + K + + + + E++ N F +VN +L++
Sbjct 127 TIFILPPSIESLKNRIQKRLTETNIQINQRLEKAKAEIKIKN--LFKFQVVNDNLEECVA 184
Query 654 ELLRLINK 661
++ ++I+K
Sbjct 185 QIEKIISK 192
>sp|Q4A8L2|KGUA_MESH7 Guanylate kinase OS=Mesomycoplasma hyopneumoniae
(strain 7448) OX=262722 GN=gmk PE=3 SV=1
Length=197
Score = 191 bits (484), Expect = 2e-55, Method: Composition-based stats.
Identities = 49/188 (26%), Positives = 85/188 (45%), Gaps = 8/188 (4%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
+ IIL GP G+ + L+ + A+ TTR +R E+ G +Y F++ Q F+
Sbjct 7 KLIILSGPSGVGKGTIESLLLKNKNLLIKLAISATTREKRRDEINGVNYFFLTVQEFKEK 66
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKP------Y 593
I +FIE N YGT ++ + + I LL + T K + +
Sbjct 67 IENDEFIEWSCHFNNYYGTLKSQIKFIQSQNFIPLLEIDTTGAKNIIENYKNKGELSQLL 126
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
IFI PPS E L+ + K + + + + E++ N F +VN +L+K
Sbjct 127 TIFILPPSIESLKNRIQKRLTETNIQINQRLEKAKAEIKVKN--LFKFQVVNDNLEKCVA 184
Query 654 ELLRLINK 661
++ ++I+K
Sbjct 185 QIEKIISK 192
>sp|Q11XI0|KGUA_CYTH3 Guanylate kinase OS=Cytophaga hutchinsonii
(strain ATCC 33406 / DSM 1761 / CIP 103989 / NBRC 15051 /
NCIMB 9469 / D465) OX=269798 GN=gmk PE=3 SV=1
Length=192
Score = 190 bits (483), Expect = 2e-55, Method: Composition-based stats.
Identities = 43/187 (23%), Positives = 81/187 (43%), Gaps = 6/187 (3%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV-AGRDYHFVSRQAFE 537
+ I P G+ + Q L+N + R ++ TR R+ + G+DY+F+S FE
Sbjct 3 GKLFIFSAPSGSGKTTVVQHLLNTDP-RIGFSISACTREMRESKEANGKDYYFLSVDEFE 61
Query 538 ADIAAGKFIEHGEFE-KNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD-LKPYII 595
I +F+E E YGT V+++ + GK + + + +L+ K +
Sbjct 62 RRIQNNEFVEWEEVYPGRYYGTLRSEVQRIWDMGKHVIFDVDVKGGLSLKEQFGDKALSV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL 655
F+ PS E L+ L + + + + E + FD +VN L++ + +
Sbjct 122 FVKVPSIEELQKRLIDRNTESEDSLKARLEK--MKYESSFQDQFDVILVNDRLEETFVKA 179
Query 656 LRLINKL 662
+LI+
Sbjct 180 HQLIDHF 186
>sp|Q2S6J5|KGUA_SALRD Guanylate kinase OS=Salinibacter ruber (strain
DSM 13855 / M31) OX=309807 GN=gmk PE=3 SV=1
Length=188
Score = 189 bits (481), Expect = 4e-55, Method: Composition-based stats.
Identities = 54/186 (29%), Positives = 85/186 (46%), Gaps = 6/186 (3%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+ ++L P G+ + R++ D +V TTR+ R E G DYHF+S + F A
Sbjct 4 RNIVVLTAPSGAGKTTIAHRVLEAMPD-MQFSVSATTRAARPDETDGVDYHFLSPEEFRA 62
Query 539 DIAAGKFIEHGEFE-KNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD-LKPYIIF 596
I AG +E+ E YGT V G LL + + ++ I+F
Sbjct 63 RIDAGDLLEYEEVYPDQFYGTLRSEVEDRAEDG-PVLLDIDVKGALNVKRIFGDDALILF 121
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELL 656
+APPS + L+ L G + E L++ +++ E E + D +VN DLD A +E L
Sbjct 122 VAPPSLDELQRRLEGRGTEDR-ESLQDRLDRV-EQEMDRADDCDAVVVNDDLDPAVEETL 179
Query 657 RLINKL 662
I +
Sbjct 180 TRIRQF 185
>sp|Q8EVJ9|KGUA_MALP2 Guanylate kinase OS=Malacoplasma penetrans
(strain HF-2) OX=272633 GN=gmk PE=3 SV=1
Length=196
Score = 187 bits (476), Expect = 2e-54, Method: Composition-based stats.
Identities = 47/177 (27%), Positives = 81/177 (46%), Gaps = 4/177 (2%)
Query 485 IGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGK 544
GP G+ + +++N ++ TTR R+ E G DY FVS + F + I G+
Sbjct 14 SGPSGVGKKTIIDQVINNVDLNLTYSISMTTRLPREHEKNGVDYFFVSEEEFNSAIEKGE 73
Query 545 FIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN--SDLKPYIIFIAPPSQ 602
+E EF N YGT I ++ ++I K +L + Q +++ + IF+ PPS
Sbjct 74 LLEWAEFANNKYGTPIKNLYKLIGENKNVILEIEVQGATKVKDILNREDYISIFLIPPSI 133
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
L+ L K + + I K ++E + +D I+N D A +L ++
Sbjct 134 RELKRRLKIRDTETKEKIKQRI--KRAKVELKLQNEYDFIILNDDAKNAADKLRHIL 188
>sp|Q4JVH4|KGUA_CORJK Guanylate kinase OS=Corynebacterium jeikeium
(strain K411) OX=306537 GN=gmk PE=3 SV=1
Length=188
Score = 187 bits (474), Expect = 3e-54, Method: Composition-based stats.
Identities = 48/169 (28%), Positives = 80/169 (47%), Gaps = 5/169 (3%)
Query 473 HQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVS 532
Q N R ++L GP G++ + +RL D F +V TTR R EV G DY +V+
Sbjct 2 SQDLNSGRIVVLAGPSAVGKSTVVRRLRTDVPDLF-FSVSMTTRDPRPGEVDGEDYIYVT 60
Query 533 RQAFEADIAAGKFIEHGEFEK--NLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL 590
R+ FE +IAA K +E E L GT + + + + + L+ + + + ++
Sbjct 61 REQFEQNIAADKMLEWAEIHGGLQLSGTPREPIEKALAESRPVLVEVDLEGARNVKKMLP 120
Query 591 KPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYF 639
+ +F+APPS E L L G + R + +T ++E + F
Sbjct 121 QVQTVFLAPPSWEELVDRLTGRGTETQDVIERRL--QTAKVEMASQSEF 167
>sp|Q4A6S7|KGUA_MYCS5 Guanylate kinase OS=Mycoplasmopsis synoviae
(strain 53) OX=262723 GN=gmk PE=3 SV=1
Length=198
Score = 186 bits (472), Expect = 8e-54, Method: Composition-based stats.
Identities = 46/191 (24%), Positives = 81/191 (42%), Gaps = 9/191 (5%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+K +I GP G+ + Q + N ++ + + TTRS R E G Y+F+S++ F+
Sbjct 5 KKSIVIFTGPSGVGKGTVEQLVFNYDELNLSLSCSATTRSPRGGETNGIHYYFISKEEFK 64
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSL-------KTLRNSDL 590
I KF+EH N YGT + +I K+ L + T + L+N
Sbjct 65 DRIKNKKFLEHSFHFDNYYGTLYSELDNIIARNKVPFLEIETNGAKIIAQKMQKLKNPPY 124
Query 591 KPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDK 650
IF++PPS + + G + + + E F + N ++
Sbjct 125 NLITIFLSPPSITDIYKRIKNRGTENAQTIKNRVNKA--KEELLEAGNFKYVVYNDRPER 182
Query 651 AYQELLRLINK 661
A QE+ +++K
Sbjct 183 AAQEIREILHK 193
>sp|Q7MAK5|KGUA_WOLSU Guanylate kinase OS=Wolinella succinogenes
(strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC
602W) OX=273121 GN=gmk PE=3 SV=1
Length=215
Score = 186 bits (473), Expect = 9e-54, Method: Composition-based stats.
Identities = 51/165 (31%), Positives = 84/165 (51%), Gaps = 4/165 (2%)
Query 495 LRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKN 554
L + L + K+ + +V TTR+ R+ E+ G+ YHFVS++ F I F+E E N
Sbjct 22 LCKTLFKEIKNAY-FSVSTTTRTPREGEIEGKHYHFVSKEKFLEGIEENFFLEWAEVHGN 80
Query 555 LYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK-PYIIFIAPPSQERLRALLAKEG 613
YGTS +SV + GK+ + + Q + ++ S + +FI P+Q+ LR L G
Sbjct 81 YYGTSKESVESALAQGKLVVFDIDIQGHRNIKESYPELTTSVFITTPTQQELRERLVLRG 140
Query 614 KNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
+ K ++ EM+ + FD IVN DL ++ + LL +
Sbjct 141 TDDKETIDLRVMHAYTEMK--HIKEFDFVIVNRDLKESEKLLLSI 183
>sp|Q10M74|GMK2_ORYSJ Guanylate kinase 2, chloroplastic/mitochondrial
OS=Oryza sativa subsp. japonica OX=39947 GN=V2 PE=1
SV=1
Length=285
Score = 185 bits (470), Expect = 2e-52, Method: Composition-based stats.
Identities = 47/196 (24%), Positives = 88/196 (45%), Gaps = 6/196 (3%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
P + +++ GP G++ + QRL +E++ V T+R++R EV G+DY+FV+++
Sbjct 87 PPPQPMILVISGPSGVGKDAVIQRL-QEEREGMHFVVTATSRAKRPGEVDGKDYYFVTKE 145
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK-PY 593
F I + +E+ G +R + G +L + Q TLR +
Sbjct 146 EFLTMIERKELLEYALVYGEYKGIPKQQIRDYMAKGYDIVLRVDIQGAATLREILGESAI 205
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNS--DLDKA 651
IF+ S+E L L L + E+++ N FD +VNS +L+ A
Sbjct 206 FIFLVAESEEALVKRLIHRKTETSDMLLVRVATAREEVKRMNN--FDYVVVNSEGNLEGA 263
Query 652 YQELLRLINKLDTEPQ 667
+++ +I+ +
Sbjct 264 VKQVESIIDAEKAKVH 279
>sp|Q8D2E8|KGUA_WIGBR Guanylate kinase OS=Wigglesworthia glossinidia
brevipalpis OX=36870 GN=gmk PE=3 SV=1
Length=207
Score = 181 bits (459), Expect = 9e-52, Method: Composition-based stats.
Identities = 49/177 (28%), Positives = 83/177 (47%), Gaps = 3/177 (2%)
Query 484 LIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAA 542
+ P G++ L + +N F ++ HTTR+ R +E+ G+DY F+S++ F+ I
Sbjct 9 ISAPSGTGKSSLIKTFLNTNLGMNFRLSISHTTRNIRSEEIEGKDYFFISKEKFKKMIFE 68
Query 543 GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQ 602
KFIE+ N YGTS V+ I S + + +K ++ K IFI PPS+
Sbjct 69 KKFIEYTYSFNNYYGTSFKEVKNKIKSNFSLFFDVNYKGVKKIKEFIPKLISIFILPPSK 128
Query 603 ERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
L L N EL + K ++ N + +D ++N D + ++ +I
Sbjct 129 LDLLKRLYNR-YNSNEFELNKRFYKYKKDILNY-NKYDFILINRDFNNTLNKIKTII 183
>sp|P0C0M8|KGUA_STAEP Guanylate kinase (Fragment) OS=Staphylococcus
epidermidis OX=1282 GN=gmk PE=3 SV=1
Length=130
Score = 177 bits (449), Expect = 2e-51, Method: Composition-based stats.
Identities = 35/130 (27%), Positives = 60/130 (46%), Gaps = 0/130 (0%)
Query 498 RLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYG 557
++ + ++ TTR R+ E+ G DY F +++ FEA I +FIE+ ++ N YG
Sbjct 1 KIFEDPTTSYKYSISMTTRHMREGEIDGVDYFFKTKEEFEALIKDDQFIEYAQYVGNYYG 60
Query 558 TSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPK 617
T + V+ + G L + + K +R IF+APPS + L+ L G
Sbjct 61 TPVQYVKDTMEEGHDVFLEIEVEGAKQVRKKFPDALFIFLAPPSLDDLKERLVGRGTESD 120
Query 618 PEELREIIEK 627
+ + E
Sbjct 121 EKIQSRVNEA 130
>sp|Q64PY1|KGUA_BACFR Guanylate kinase OS=Bacteroides fragilis
(strain YCH46) OX=295405 GN=gmk PE=3 SV=1
Length=204
Score = 180 bits (456), Expect = 2e-51, Method: Composition-based stats.
Identities = 48/198 (24%), Positives = 84/198 (42%), Gaps = 6/198 (3%)
Query 467 EEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGR 526
E ++ H+ + II P G++ + L+ + K A ++ T+R R E G
Sbjct 5 ERITTPHKTGE-AKVIIFSAPSGSGKSTIINYLLAQ-KLNLAFSISATSRPPRGNEKHGV 62
Query 527 DYHFVSRQAFEADIAAGKFIEHGEFE-KNLYGTSIDSVRQVINSGKICLLSLRTQSLKTL 585
+Y F+S F IA +F+E+ E YGT V + + +G+ + + +
Sbjct 63 EYFFLSPDEFRQRIANNEFLEYEEVYTDRFYGTLKAQVEKQLAAGQNVVFDVDVVGGCNI 122
Query 586 RNSDLK-PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIV 644
+ + +FI PP + LR L G + I + E E + FD I+
Sbjct 123 KKYYGERALSLFIQPPCIDELRRRLIGRGTDTPEVIESRIAKA--EYELSFAPKFDKVII 180
Query 645 NSDLDKAYQELLRLINKL 662
N DL+ A L++I +
Sbjct 181 NDDLETAKAHALKVIKEF 198
>sp|Q5L9N9|KGUA_BACFN Guanylate kinase OS=Bacteroides fragilis
(strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC
9343 / Onslow) OX=272559 GN=gmk PE=3 SV=1
Length=204
Score = 180 bits (456), Expect = 2e-51, Method: Composition-based stats.
Identities = 48/198 (24%), Positives = 84/198 (42%), Gaps = 6/198 (3%)
Query 467 EEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGR 526
E ++ H+ + II P G++ + L+ + K A ++ T+R R E G
Sbjct 5 ERITTPHKTGE-AKVIIFSAPSGSGKSTIINYLLAQ-KLNLAFSISATSRPPRGNEKHGV 62
Query 527 DYHFVSRQAFEADIAAGKFIEHGEFE-KNLYGTSIDSVRQVINSGKICLLSLRTQSLKTL 585
+Y F+S F IA +F+E+ E YGT V + + +G+ + + +
Sbjct 63 EYFFLSPDEFRQRIANNEFLEYEEVYTDRFYGTLKAQVEKQLAAGQNVVFDVDVVGGCNI 122
Query 586 RNSDLK-PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIV 644
+ + +FI PP + LR L G + I + E E + FD I+
Sbjct 123 KKYYGERALSLFIQPPCIDELRRRLIGRGTDTPEVIESRIAKA--EYELSFAPKFDKVII 180
Query 645 NSDLDKAYQELLRLINKL 662
N DL+ A L++I +
Sbjct 181 NDDLETAKAHALKVIKEF 198
>sp|Q94JM2|GMK3_ARATH Guanylate kinase 3, chloroplastic OS=Arabidopsis
thaliana OX=3702 GN=GK3 PE=2 SV=1
Length=282
Score = 177 bits (450), Expect = 1e-49, Method: Composition-based stats.
Identities = 42/189 (22%), Positives = 79/189 (42%), Gaps = 6/189 (3%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I++ GP G++ + +L + ++ V T+R R EV G+DY FVSR F + +
Sbjct 91 IVISGPSGVGKDAVINKL-REVREGLHFVVTATSRPMRPGEVDGKDYFFVSRDQFLSMVE 149
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK-PYIIFIAPP 600
+ +E+ G +++ + G+ +L + Q +TLR IF+
Sbjct 150 NEELLEYALVYGEYKGIPKKQIQEFMAKGEDIVLRVDIQGAQTLRRILGNSAVFIFLVAE 209
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVN--SDLDKAYQELLRL 658
S+ + L + E L + E+ + FD +VN LD A + +
Sbjct 210 SELAMVERLIDRKTESQEELLVRVATAREEVR--HLKNFDYVVVNAKGRLDDAVNRVESI 267
Query 659 INKLDTEPQ 667
I+ ++
Sbjct 268 IDAEKSKVH 276
>sp|Q6KH87|KGUA_MESM1 Guanylate kinase OS=Mesomycoplasma mobile
(strain ATCC 43663 / 163K / NCTC 11711) OX=267748 GN=gmk PE=3
SV=1
Length=201
Score = 167 bits (422), Expect = 1e-46, Method: Composition-based stats.
Identities = 49/195 (25%), Positives = 81/195 (42%), Gaps = 8/195 (4%)
Query 477 NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ + IIL GP G+ + + L+ EK + + T+R R E+ G+DY F S + F
Sbjct 8 HHGKIIILSGPSGVGKGSIEKLLLEDEKLKLKFSTSVTSRKPRVNEIEGKDYFFRSEEEF 67
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTL------RNSDL 590
I KFIE N YGT V +++ + L+ + T + +N
Sbjct 68 SELIKEKKFIEWSRHLNNYYGTLKSEVDKILGAKFNVLIEIETTGALNILKYYKKKNMLN 127
Query 591 KPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDK 650
IFI PP E L + G K E I + + E + F + N+ L +
Sbjct 128 DVISIFILPPRLEELETRILNRGSETKEEIKIRIKK--AKKEIKLKNKFKYNLTNNFLHE 185
Query 651 AYQELLRLINKLDTE 665
+E+ ++ + E
Sbjct 186 CVEEVKNILKREIHE 200
>sp|Q9D5S7|LRGUK_MOUSE Leucine-rich repeat and guanylate kinase
domain-containing protein OS=Mus musculus OX=10090 GN=Lrguk
PE=1 SV=1
Length=820
Score = 174 bits (440), Expect = 2e-44, Method: Composition-based stats.
Identities = 52/183 (28%), Positives = 87/183 (48%), Gaps = 2/183 (1%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
+IL GP CG+ EL RL + F HTTR E DYHF+S++ F+ +
Sbjct 416 MLILTGPAACGKRELAHRLCRQFSTYFRYGACHTTRPPYFGEGDRVDYHFISQEVFDEML 475
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
GKFI + + YG + D++ + G + + + +++L+ S +P I + P
Sbjct 476 NMGKFILTFNYGNHNYGLNRDTIEGIARDGLASCIHMELEGVRSLKYSYFEPRYILVVPM 535
Query 601 SQERLRALLAKEGKNPKPEELRE--IIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
+E+ L ++G + E ++ ++ Q YFD I D+D AYQ+L L
Sbjct 536 DKEKYEGYLRRKGLFSRAEIEIAVSRVDLYVKVNQKYPGYFDAVINADDMDIAYQKLSEL 595
Query 659 INK 661
I +
Sbjct 596 IRE 598
>sp|Q96M69|LRGUK_HUMAN Leucine-rich repeat and guanylate kinase
domain-containing protein OS=Homo sapiens OX=9606 GN=LRGUK
PE=1 SV=1
Length=825
Score = 173 bits (439), Expect = 3e-44, Method: Composition-based stats.
Identities = 55/183 (30%), Positives = 90/183 (49%), Gaps = 2/183 (1%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
+IL GP+ CG+ EL RL + F HTTR E DYHF+S+ F+ +
Sbjct 416 MLILAGPEACGKRELAHRLCRQFSTYFRYGACHTTRPPYFGEGDRVDYHFISQDVFDEMV 475
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
GKFI + + YG + D+V + G + + + +++L+ S +P I + P
Sbjct 476 NMGKFILTFSYGNHKYGLNRDTVEGIARDGLASCIHMEIEGVRSLKYSYFEPRYILVVPM 535
Query 601 SQERLRALLAKEGKNPKPEE--LREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
++E+ L ++G + E ++ ++ QN YFD I DLD AYQ+L +L
Sbjct 536 NKEKYEGYLRRKGLFSRAEIEFAVSRVDLYIKINQNFPGYFDEVINADDLDVAYQKLSQL 595
Query 659 INK 661
I +
Sbjct 596 IRE 598
>sp|Q01230|A57_VACCW Guanylate kinase homolog OS=Vaccinia virus
(strain Western Reserve) OX=10254 GN=VACWR182 PE=3 SV=3
Length=151
Score = 143 bits (361), Expect = 1e-38, Method: Composition-based stats.
Identities = 49/141 (35%), Positives = 78/141 (55%), Gaps = 1/141 (1%)
Query 522 EVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS 581
E G DYH+V+R+A IAAG F+EH EF N+YGTS +V + +IC++ L
Sbjct 2 EREGVDYHYVNREAIWKGIAAGNFLEHTEFLGNIYGTSKTAVNTAAINNRICVMDLNIDG 61
Query 582 LKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREM-EQNNGHYFD 640
+++L+N+ L PY ++I P S + + L E R +I +M E N FD
Sbjct 62 VRSLKNTYLMPYSVYIRPTSLKMVETKLRCRNTEANDEIHRRVILAKTDMDEANEAGLFD 121
Query 641 TAIVNSDLDKAYQELLRLINK 661
T I+ D++ AY +L++++
Sbjct 122 TIIIEDDVNLAYSKLIQILQD 142
>sp|P21074|A57_VACCC Guanylate kinase homolog OS=Vaccinia virus
(strain Copenhagen) OX=10249 GN=A57R PE=3 SV=3
Length=151
Score = 140 bits (354), Expect = 7e-38, Method: Composition-based stats.
Identities = 48/141 (34%), Positives = 77/141 (55%), Gaps = 1/141 (1%)
Query 522 EVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS 581
E G DYH+V+R+A IAAG F+EH EF N+YGTS +V + +IC++ L
Sbjct 2 EREGVDYHYVNREAIWKGIAAGNFLEHTEFLGNIYGTSKTAVNTAAINNRICVMDLNIDG 61
Query 582 LKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREM-EQNNGHYFD 640
+++ +N+ L PY ++I P S + + L E R +I +M E N FD
Sbjct 62 VRSFKNTYLMPYSVYIRPTSLKMVETKLRCRNTEANDEIHRRVILAKTDMDEANEAGLFD 121
Query 641 TAIVNSDLDKAYQELLRLINK 661
T I+ D++ AY +L++++
Sbjct 122 TIIIEDDVNLAYSKLIQILQD 142
>sp|Q9Z101|PAR6A_MOUSE Partitioning defective 6 homolog alpha
OS=Mus musculus OX=10090 GN=Pard6a PE=1 SV=2
Length=346
Score = 96.3 bits (238), Expect = 3e-20, Method: Composition-based stats.
Identities = 53/197 (27%), Positives = 83/197 (42%), Gaps = 34/197 (17%)
Query 162 AFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALL 221
+ N ++H AS P PL Q A+ + L + + LL P
Sbjct 68 LLPLTNDDSLHRALASGPPPLRLLVQKRAEGDSSGLAFASNSLQRRKKGLLLRP------ 121
Query 222 LAHDKVAEQEMQLEPITDERVYESIGQYG--------GETVKIVRIEK-ARDIPLGATVR 272
VA ++ P + + Q ET + VR+ K D PLG +R
Sbjct 122 -----VAP--LRTRPPLLISLPQDFRQVSSVIDVDLLPETHRRVRLHKHGSDRPLGFYIR 174
Query 273 N------------EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDL 320
+ + + ISR+V+GG AE +GLL DE+LE+NGIE+ GK +++V D+
Sbjct 175 DGMSVRVAPQGLERVPGIFISRLVRGGLAESTGLLAVSDEILEVNGIEVAGKTLDQVTDM 234
Query 321 LSDMHGTLTFVLIPSQQ 337
+ L + P+ Q
Sbjct 235 MVANSHNLIVTVKPANQ 251
>sp|Q6B4M5|PAR6A_RAT Partitioning defective 6 homolog alpha OS=Rattus
norvegicus OX=10116 GN=Pard6a PE=1 SV=2
Length=346
Score = 95.9 bits (237), Expect = 4e-20, Method: Composition-based stats.
Identities = 53/197 (27%), Positives = 83/197 (42%), Gaps = 34/197 (17%)
Query 162 AFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALL 221
+ N ++H AS P PL Q A+ + L + + LL P
Sbjct 68 LLPLTNDDSLHRALASGPPPLRLLVQKRAEGDSSGLAFASNSLQRRKKGLLLRP------ 121
Query 222 LAHDKVAEQEMQLEPITDERVYESIGQYG--------GETVKIVRIEK-ARDIPLGATVR 272
VA ++ P + + Q ET + VR+ K D PLG +R
Sbjct 122 -----VAP--LRTRPPLLISLPQDFRQVSSVIDVDLLPETHRRVRLHKHGSDRPLGFYIR 174
Query 273 N------------EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDL 320
+ + + ISR+V+GG AE +GLL DE+LE+NGIE+ GK +++V D+
Sbjct 175 DGMSVRVAPQGLERVPGIFISRLVRGGLAESTGLLAVSDEILEVNGIEVAGKTLDQVTDM 234
Query 321 LSDMHGTLTFVLIPSQQ 337
+ L + P+ Q
Sbjct 235 MVANSHNLIVTVKPANQ 251
>sp|Q9NPB6|PAR6A_HUMAN Partitioning defective 6 homolog alpha
OS=Homo sapiens OX=9606 GN=PARD6A PE=1 SV=1
Length=346
Score = 94.0 bits (232), Expect = 2e-19, Method: Composition-based stats.
Identities = 53/197 (27%), Positives = 83/197 (42%), Gaps = 34/197 (17%)
Query 162 AFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALL 221
+ N ++H AS P PL Q A+ + L + + LL P
Sbjct 68 LLPLTNDDSLHRALASGPPPLRLLVQKRAEADSSGLAFASNSLQRRKKGLLLRP------ 121
Query 222 LAHDKVAEQEMQLEPITDERVYESIGQYG--------GETVKIVRIEK-ARDIPLGATVR 272
VA ++ P + + Q ET + VR+ K D PLG +R
Sbjct 122 -----VAP--LRTRPPLLISLPQDFRQVSSVIDVDLLPETHRRVRLHKHGSDRPLGFYIR 174
Query 273 N------------EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDL 320
+ + + ISR+V+GG AE +GLL DE+LE+NGIE+ GK +++V D+
Sbjct 175 DGMSVRVAPQGLERVPGIFISRLVRGGLAESTGLLAVSDEILEVNGIEVAGKTLDQVTDM 234
Query 321 LSDMHGTLTFVLIPSQQ 337
+ L + P+ Q
Sbjct 235 MVANSHNLIVTVKPANQ 251
>sp|Q9NAN2|PAR6_CAEEL Partitioning defective protein 6 OS=Caenorhabditis
elegans OX=6239 GN=par-6 PE=1 SV=2
Length=309
Score = 92.4 bits (228), Expect = 4e-19, Method: Composition-based stats.
Identities = 35/103 (34%), Positives = 55/103 (53%), Gaps = 13/103 (13%)
Query 248 QYGGETVKIVRIEK-ARDIPLGATVRN------------EMDSVIISRIVKGGAAEKSGL 294
E + VR+ K ++ PLG +R+ ++ + ISR+V GG AE +GL
Sbjct 148 DIVPEAHRRVRLCKHGQERPLGFYIRDGTSVRVTERGVVKVSGIFISRLVDGGLAESTGL 207
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
L DEVLE+NGIE+ GK +++V D++ L + P+ Q
Sbjct 208 LGVNDEVLEVNGIEVLGKTLDQVTDMMVANAHNLIITVKPANQ 250
>sp|Q9BYG5|PAR6B_HUMAN Partitioning defective 6 homolog beta OS=Homo
sapiens OX=9606 GN=PARD6B PE=1 SV=1
Length=372
Score = 93.2 bits (230), Expect = 4e-19, Method: Composition-based stats.
Identities = 35/113 (31%), Positives = 55/113 (49%), Gaps = 13/113 (12%)
Query 248 QYGGETVKIVRIEK-ARDIPLGATVRN------------EMDSVIISRIVKGGAAEKSGL 294
ET + VR+ K + PLG +R+ ++ + ISR+V GG A+ +GL
Sbjct 149 DILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGL 208
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV 347
L DEVLE+NGIE+ GK +++V D++ L + P+ Q
Sbjct 209 LAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSRT 261
>sp|Q9JK84|PAR6G_MOUSE Partitioning defective 6 homolog gamma
OS=Mus musculus OX=10090 GN=Pard6g PE=2 SV=1
Length=382
Score = 93.2 bits (230), Expect = 4e-19, Method: Composition-based stats.
Identities = 35/113 (31%), Positives = 55/113 (49%), Gaps = 13/113 (12%)
Query 248 QYGGETVKIVRIEK-ARDIPLGATVRN------------EMDSVIISRIVKGGAAEKSGL 294
ET + VR+ + + PLG +R+ ++ + ISR+V GG AE +GL
Sbjct 150 DILPETHRRVRLYRHGYEKPLGFYIRDGTSVRVTPHGLEKVPGIFISRMVPGGLAESTGL 209
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV 347
L DEVLE+NGIE+ GK +++V D++ L + P+ Q
Sbjct 210 LAVNDEVLEVNGIEVAGKTLDQVTDMMIANSHNLIVTVKPANQRNNVVRSSRT 262
>sp|Q9BYG4|PAR6G_HUMAN Partitioning defective 6 homolog gamma
OS=Homo sapiens OX=9606 GN=PARD6G PE=1 SV=1
Length=376
Score = 92.8 bits (229), Expect = 6e-19, Method: Composition-based stats.
Identities = 35/103 (34%), Positives = 55/103 (53%), Gaps = 13/103 (13%)
Query 248 QYGGETVKIVRIEK-ARDIPLGATVRN------------EMDSVIISRIVKGGAAEKSGL 294
ET + VR+ + + PLG +R+ ++ + ISR+V GG AE +GL
Sbjct 150 DLVPETHRRVRLHRHGCEKPLGFYIRDGASVRVTPHGLEKVPGIFISRMVPGGLAESTGL 209
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
L DEVLE+NGIE+ GK +++V D++ L + P+ Q
Sbjct 210 LAVNDEVLEVNGIEVAGKTLDQVTDMMIANSHNLIVTVKPANQ 252
>sp|Q9Z250|LIN7A_RAT Protein lin-7 homolog A OS=Rattus norvegicus
OX=10116 GN=Lin7a PE=1 SV=2
Length=232
Score = 89.3 bits (220), Expect = 1e-18, Method: Composition-based stats.
Identities = 37/166 (22%), Positives = 72/166 (43%), Gaps = 12/166 (7%)
Query 183 ISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLA----HDKVAEQ---EMQLE 235
++ A +L +++Q + HK Q L +L + A+ H+ + E +
Sbjct 29 VARAIELLEKLQESGEVPVHK-LQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEFRAR 87
Query 236 PITDERVYESIGQYGGETVKIVRIEKARDIPLGA---TVRNEMDSVIISRIVKGGAAEKS 292
V G ++V + K D LG + + + ISRI+ GG AE+
Sbjct 88 ATAKATVAAFAASEGHSHPRVVELPK-TDEGLGFNVMGGKEQNSPIYISRIIPGGVAERH 146
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
G L GD++L +NG+ + G+ + +LL ++ V+ + ++
Sbjct 147 GGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKV 192
>sp|Q8JZS0|LIN7A_MOUSE Protein lin-7 homolog A OS=Mus musculus
OX=10090 GN=Lin7a PE=1 SV=2
Length=233
Score = 89.3 bits (220), Expect = 1e-18, Method: Composition-based stats.
Identities = 37/166 (22%), Positives = 72/166 (43%), Gaps = 12/166 (7%)
Query 183 ISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLA----HDKVAEQ---EMQLE 235
++ A +L +++Q + HK Q L +L + A+ H+ + E +
Sbjct 29 VARAIELLEKLQESGEVPVHK-LQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEFRAR 87
Query 236 PITDERVYESIGQYGGETVKIVRIEKARDIPLGA---TVRNEMDSVIISRIVKGGAAEKS 292
V G ++V + K D LG + + + ISRI+ GG AE+
Sbjct 88 ATAKATVAAFAASEGHSHPRVVELPK-TDEGLGFNVMGGKEQNSPIYISRIIPGGVAERH 146
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
G L GD++L +NG+ + G+ + +LL ++ V+ + ++
Sbjct 147 GGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKV 192
>sp|O14910|LIN7A_HUMAN Protein lin-7 homolog A OS=Homo sapiens
OX=9606 GN=LIN7A PE=1 SV=2
Length=233
Score = 89.3 bits (220), Expect = 1e-18, Method: Composition-based stats.
Identities = 37/166 (22%), Positives = 72/166 (43%), Gaps = 12/166 (7%)
Query 183 ISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLA----HDKVAEQ---EMQLE 235
++ A +L +++Q + HK Q L +L + A+ H+ + E +
Sbjct 29 VARAIELLEKLQESGEVPVHK-LQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEFRAR 87
Query 236 PITDERVYESIGQYGGETVKIVRIEKARDIPLGA---TVRNEMDSVIISRIVKGGAAEKS 292
V G ++V + K D LG + + + ISRI+ GG AE+
Sbjct 88 ATAKATVAAFAASEGHSHPRVVELPK-TDEGLGFNVMGGKEQNSPIYISRIIPGGVAERH 146
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
G L GD++L +NG+ + G+ + +LL ++ V+ + ++
Sbjct 147 GGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKV 192
>sp|Q32LM6|LIN7A_BOVIN Protein lin-7 homolog A OS=Bos taurus OX=9913
GN=LIN7A PE=2 SV=1
Length=233
Score = 89.3 bits (220), Expect = 1e-18, Method: Composition-based stats.
Identities = 37/166 (22%), Positives = 72/166 (43%), Gaps = 12/166 (7%)
Query 183 ISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLA----HDKVAEQ---EMQLE 235
++ A +L +++Q + HK Q L +L + A+ H+ + E +
Sbjct 29 VARAIELLEKLQESGEVPVHK-LQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEFRAR 87
Query 236 PITDERVYESIGQYGGETVKIVRIEKARDIPLGA---TVRNEMDSVIISRIVKGGAAEKS 292
V G ++V + K D LG + + + ISRI+ GG AE+
Sbjct 88 ATAKATVAAFAASEGHSHPRVVELPK-TDEGLGFNVMGGKEQNSPIYISRIIPGGVAERH 146
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
G L GD++L +NG+ + G+ + +LL ++ V+ + ++
Sbjct 147 GGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKV 192
>sp|Q9C0E4|GRIP2_HUMAN Glutamate receptor-interacting protein
2 OS=Homo sapiens OX=9606 GN=GRIP2 PE=1 SV=4
Length=1043
Score = 94.4 bits (233), Expect = 2e-18, Method: Composition-based stats.
Identities = 31/103 (30%), Positives = 50/103 (49%), Gaps = 3/103 (3%)
Query 261 KARDIPLGATVRN---EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
K PLG T+ D ++IS + K G AE++G +H GD +L IN + ++G+ ++E
Sbjct 660 KRYGGPLGITISGTEEPFDPIVISGLTKRGLAERTGAIHVGDRILAINNVSLKGRPLSEA 719
Query 318 FDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
LL T+T + P K + + D DP+D
Sbjct 720 IHLLQVAGETVTLKIKKQLDRPLLPRKSGSLSETSDADEDPAD 762
Score = 66.2 bits (160), Expect = 7e-10, Method: Composition-based stats.
Identities = 22/112 (20%), Positives = 40/112 (36%), Gaps = 9/112 (8%)
Query 226 KVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDS-----VII 280
V E E +L P E + +TV + ++ D +++
Sbjct 123 VVLEVEYELPPPAPENNP----RIISKTVDVSLYKEGNSFGFVLRGGAHEDGHKSRPLVL 178
Query 281 SRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ + GG A++ G L GD +L ++GI + G L F +
Sbjct 179 TYVRPGGPADREGSLKVGDRLLSVDGIPLHGASHATALATLRQCSHEALFQV 230
Score = 66.2 bits (160), Expect = 7e-10, Method: Composition-based stats.
Identities = 33/148 (22%), Positives = 59/148 (40%), Gaps = 13/148 (9%)
Query 223 AHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVR----NEMDSV 278
+H+ + + E + T + V + G +V I K LG ++ +
Sbjct 223 SHEALFQVEYDVA--TPDTVANASGPL------MVEIVKTPGSALGISLTTTSLRNKSVI 274
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
I RI ++SG LH GD +L I+G + + E LL+ + + ++P Q
Sbjct 275 TIDRIKPASVVDRSGALHPGDHILSIDGTSMEHCSLLEATKLLASISEKVRLEILPVPQS 334
Query 339 KPPPAKETVIHVKAHFDYDPSDDPYVPC 366
+ P + V+ + DP VP
Sbjct 335 QRPLRPSEAVKVQ-RSEQLHRWDPCVPS 361
Score = 63.2 bits (152), Expect = 6e-09, Method: Composition-based stats.
Identities = 32/116 (28%), Positives = 51/116 (44%), Gaps = 14/116 (12%)
Query 222 LAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV----RNEMDS 277
LAH V E E + E V S G + V++ K R + LG T+ R +
Sbjct 533 LAHKVVLEVEFDVA----ESVIPSSGTFH------VKLPKKRSVELGITISSASRKRGEP 582
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
+IIS I KG A ++G L GD++L I+ I + + + +L + +
Sbjct 583 LIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDNCPMEDAVQILRQCEDLVKLKIR 638
Score = 59.7 bits (143), Expect = 7e-08, Method: Composition-based stats.
Identities = 23/97 (24%), Positives = 40/97 (41%), Gaps = 3/97 (3%)
Query 256 IVRIEKARDIPLGATVRNEMDS---VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
+V + K LG T+ D +S + GG A +S LL+ GD + +NGI +
Sbjct 48 VVELIKKEGSTLGLTISGGTDKDGKPRVSNLRPGGLAARSDLLNIGDYIRSVNGIHLTRL 107
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIH 349
+E+ LL ++ + + P +I
Sbjct 108 RHDEIITLLKNVGERVVLEVEYELPPPAPENNPRIIS 144
Score = 53.5 bits (127), Expect = 6e-06, Method: Composition-based stats.
Identities = 23/74 (31%), Positives = 28/74 (38%), Gaps = 1/74 (1%)
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
++ I AE+ GLL GD VL INGI + E LL D VL +
Sbjct 486 LVCFIEPDSPAERCGLLQVGDRVLSINGIATEDGTMEEANQLLRDAALAHKVVLEVEFDV 545
Query 339 KPPPA-KETVIHVK 351
HVK
Sbjct 546 AESVIPSSGTFHVK 559
Score = 47.0 bits (110), Expect = 7e-04, Method: Composition-based stats.
Identities = 27/181 (15%), Positives = 56/181 (31%), Gaps = 13/181 (7%)
Query 177 SPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLA--------HDKVA 228
+ P P + + + L+ + EL L + + H +
Sbjct 857 TSPAPGPAREEGFWRMFGEALEDLESCGQSELLRELEASIMTGTVQRVALEGRPGH-RPW 915
Query 229 EQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEM--DSVIISRIVKG 286
++ ++ E E + E K+ + G +V + + V + +
Sbjct 916 QRGREVRASPAEM-EELLLPTPLEMHKVTLHKDPMRHDFGFSVSDGLLEKGVYVHTVRPD 974
Query 287 GAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKET 346
G A + G L D VL++N + R D LL++ L ++
Sbjct 975 GPAHR-GGLQPFDRVLQVNHVRTRDFDCCLAVPLLAEAGDVLELIISRKPHTAHSSRAPR 1033
Query 347 V 347
Sbjct 1034 S 1034
>sp|Q9JK83|PAR6B_MOUSE Partitioning defective 6 homolog beta OS=Mus
musculus OX=10090 GN=Pard6b PE=1 SV=2
Length=371
Score = 91.3 bits (225), Expect = 2e-18, Method: Composition-based stats.
Identities = 35/103 (34%), Positives = 55/103 (53%), Gaps = 13/103 (13%)
Query 248 QYGGETVKIVRIEK-ARDIPLGATVRN------------EMDSVIISRIVKGGAAEKSGL 294
ET + VR+ K + PLG +R+ ++ + ISR+V GG A+ +GL
Sbjct 149 DILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGL 208
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
L DEVLE+NGIE+ GK +++V D++ L + P+ Q
Sbjct 209 LAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQ 251
>sp|Q9WTW1|GRIP2_RAT Glutamate receptor-interacting protein 2
OS=Rattus norvegicus OX=10116 GN=Grip2 PE=1 SV=1
Length=1043
Score = 92.0 bits (227), Expect = 7e-18, Method: Composition-based stats.
Identities = 42/197 (21%), Positives = 75/197 (38%), Gaps = 10/197 (5%)
Query 243 YESIGQYGGETVKIVRIEKARDIPLGATVRN---EMDSVIISRIVKGGAAEKSGLLHEGD 299
S Q V K PLG T+ D +IIS + K G AE++G +H GD
Sbjct 644 DNSDEQESSGAVSYTVELKRYGGPLGITISGTEEPFDPIIISGLTKRGLAERTGAIHVGD 703
Query 300 EVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPS 359
+L IN + ++G+ ++E LL T+T + P + + + D DP
Sbjct 704 RILAINSVSLKGRPLSEAIHLLQVAGETVTLKIKKQLDRPLLPRQSGSLSEASDVDEDPP 763
Query 360 DDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYRE---GDEDNQPLAGLVPGKSFQQQR 416
+ + L+ + + +W + E G + V + Q+ R
Sbjct 764 E----ALKGGLLTTHFSPAVPSVDSAVESWGSSATEGGFGGSGSYTPQVAVRSVTPQEWR 819
Query 417 EAMKQTIEEDKEPEKSG 433
+ ++ EP ++
Sbjct 820 SSRLKSSPPPLEPRRTS 836
Score = 65.8 bits (159), Expect = 8e-10, Method: Composition-based stats.
Identities = 23/112 (21%), Positives = 42/112 (38%), Gaps = 9/112 (8%)
Query 226 KVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIP--LGATVRNEMD---SVII 280
V E E +L P E + +TV + ++ L ++ +++
Sbjct 128 VVLEVEYELPPPAPENNP----RIISKTVDVSLYKEGNSFGFVLRGGAHEDLHKSRPLVL 183
Query 281 SRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ + GG A++ G L GD +L I+GI + G L F +
Sbjct 184 TYVRPGGPADREGSLKVGDRLLSIDGIPLHGASHATAIATLQQCSHEALFQV 235
Score = 62.0 bits (149), Expect = 1e-08, Method: Composition-based stats.
Identities = 30/143 (21%), Positives = 58/143 (41%), Gaps = 15/143 (10%)
Query 223 AHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV----RNEMDSV 278
+H+ + + E + T + V + G +V I K LG ++ ++
Sbjct 228 SHEALFQVEYDVA--TPDTVANASGPL------VVEIAKTPGSALGISLTTGSHRNKPAI 279
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
I RI ++SG LH GD +L I+G + E LL+ + + ++P+ Q
Sbjct 280 TIDRIKPASVVDRSGALHAGDHILAIDGTSTEHCSLVEATKLLASVTEKVRLEILPAPQS 339
Query 339 KPPPAKETVIHVK---AHFDYDP 358
+ P + ++ +DP
Sbjct 340 RRPLKPPEAVRIQRSEQLHHWDP 362
Score = 60.1 bits (144), Expect = 6e-08, Method: Composition-based stats.
Identities = 23/97 (24%), Positives = 40/97 (41%), Gaps = 3/97 (3%)
Query 256 IVRIEKARDIPLGATVRNEMDS---VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
+V + K LG T+ D +S + GG A +S LL+ GD + +NGI +
Sbjct 53 MVELIKREGSTLGLTISGGTDKDGKPRVSNLRPGGLAARSDLLNVGDYIRSVNGIRLTRL 112
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIH 349
+E+ LL ++ + + P +I
Sbjct 113 RHDEIITLLKNVGERVVLEVEYELPPPAPENNPRIIS 149
Score = 60.1 bits (144), Expect = 6e-08, Method: Composition-based stats.
Identities = 22/97 (23%), Positives = 40/97 (41%), Gaps = 4/97 (4%)
Query 257 VRIEKARDIPLGATV----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
V++ K R + LG T+ R + +IIS I KG A ++G L GD++L I+ I +
Sbjct 560 VKLPKRRGVELGITISSASRKRGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDHC 619
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIH 349
+ +L + + + +
Sbjct 620 PMEYAVQILRQCEDLVKLKIRKDEDNSDEQESSGAVS 656
Score = 52.8 bits (125), Expect = 9e-06, Method: Composition-based stats.
Identities = 23/74 (31%), Positives = 28/74 (38%), Gaps = 1/74 (1%)
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
++ I AE+ GLL GD VL INGI + E LL D VL +
Sbjct 488 LVRFIEPDSPAERCGLLQVGDRVLAINGIATEDGTMEEANQLLRDAALARKVVLEIEFDV 547
Query 339 KPPPA-KETVIHVK 351
HVK
Sbjct 548 AESVIPSSGTFHVK 561
Score = 45.4 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 30/186 (16%), Positives = 58/186 (31%), Gaps = 23/186 (12%)
Query 174 NKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQ 233
P P + + + + L+ + EL L + V +
Sbjct 855 EPPMSPAPGPAREEGFWRVLGEALEDLESCGQSELLRELEASIMTG------TVQSVAVD 908
Query 234 LEP------------ITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEM--DSVI 279
P + E + E + E ++ + G +V + + V
Sbjct 909 GRPGSRPWRRSREVGTSPEDLQELLLPTPLEMHRVTLHKDPVRNDFGFSVSDGLLEKGVY 968
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI--PSQQ 337
+ + G A + G L D +L++N + R D LL++ L V+ P Q
Sbjct 969 VHTVRIDGPA-QHGGLQPFDRLLQVNHVRTRDFDCCLAVPLLAEAGDILELVVSRNPLAQ 1027
Query 338 IKPPPA 343
+ P
Sbjct 1028 SRRTPG 1033
>sp|O88951|LIN7B_MOUSE Protein lin-7 homolog B OS=Mus musculus
OX=10090 GN=Lin7b PE=1 SV=2
Length=207
Score = 85.9 bits (211), Expect = 8e-18, Method: Composition-based stats.
Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 12/166 (7%)
Query 183 ISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAH-------DKVAEQEMQLE 235
+S A +L + +Q + ++ Q L +L + A+ + D E++
Sbjct 14 VSRAVELLERLQRS-GELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEVRAH 72
Query 236 PITDERVYESIGQYGGETVKIVRIEKARDIPLGA---TVRNEMDSVIISRIVKGGAAEKS 292
V G ++V + K D LG + + + ISR++ GG A++
Sbjct 73 ATAKATVAAFTASEGHAHPRVVELPK-TDEGLGFNIMGGKEQNSPIYISRVIPGGVADRH 131
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
G L GD++L +NG+ + G+ + +LL G++ V+ + ++
Sbjct 132 GGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGSVKLVVRYTPRV 177
>sp|Q9Z252|LIN7B_RAT Protein lin-7 homolog B OS=Rattus norvegicus
OX=10116 GN=Lin7b PE=1 SV=1
Length=207
Score = 85.9 bits (211), Expect = 9e-18, Method: Composition-based stats.
Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 12/166 (7%)
Query 183 ISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAH-------DKVAEQEMQLE 235
+S A +L + +Q + ++ Q L +L + A+ + D E++
Sbjct 14 VSRAVELLERLQRS-GELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEVRAH 72
Query 236 PITDERVYESIGQYGGETVKIVRIEKARDIPLGA---TVRNEMDSVIISRIVKGGAAEKS 292
V G ++V + K D LG + + + ISR++ GG A++
Sbjct 73 ATAKATVAAFTASEGHAHPRVVELPK-TDEGLGFNIMGGKEQNSPIYISRVIPGGVADRH 131
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
G L GD++L +NG+ + G+ + +LL G++ V+ + ++
Sbjct 132 GGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGSVKLVVRYTPRV 177
>sp|Q2KIB6|LIN7B_BOVIN Protein lin-7 homolog B OS=Bos taurus OX=9913
GN=LIN7B PE=2 SV=1
Length=201
Score = 85.5 bits (210), Expect = 9e-18, Method: Composition-based stats.
Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 12/166 (7%)
Query 183 ISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAH-------DKVAEQEMQLE 235
+S A +L + +Q + ++ Q L +L + A+ + D E++
Sbjct 14 VSRAVELLERLQRS-GELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEIRAH 72
Query 236 PITDERVYESIGQYGGETVKIVRIEKARDIPLGA---TVRNEMDSVIISRIVKGGAAEKS 292
V G ++V + K D LG + + + ISR++ GG A++
Sbjct 73 ATAKATVAAFTASEGHAHPRVVELPK-TDEGLGFNIMGGKEQNSPIYISRVIPGGVADRH 131
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
G L GD++L +NG+ + G+ + +LL G++ V+ + ++
Sbjct 132 GGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPRV 177
>sp|Q9HAP6|LIN7B_HUMAN Protein lin-7 homolog B OS=Homo sapiens
OX=9606 GN=LIN7B PE=1 SV=1
Length=207
Score = 85.5 bits (210), Expect = 1e-17, Method: Composition-based stats.
Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 12/166 (7%)
Query 183 ISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAH-------DKVAEQEMQLE 235
+S A +L + +Q + ++ Q L +L + A+ + D E++
Sbjct 14 VSRAVELLERLQRS-GELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEIRAH 72
Query 236 PITDERVYESIGQYGGETVKIVRIEKARDIPLGA---TVRNEMDSVIISRIVKGGAAEKS 292
V G ++V + K D LG + + + ISR++ GG A++
Sbjct 73 ATAKATVAAFTASEGHAHPRVVELPK-TDEGLGFNIMGGKEQNSPIYISRVIPGGVADRH 131
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
G L GD++L +NG+ + G+ + +LL G++ V+ + ++
Sbjct 132 GGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPRV 177
>sp|Q16A32|RBKTP_ROSDO Bifunctional ribose 1,5-bisphosphokinase-thymidine
phosphorylase OS=Roseobacter denitrificans (strain
ATCC 33942 / OCh 114) OX=375451 GN=phnN PE=3 SV=1
Length=677
Score = 90.5 bits (223), Expect = 1e-17, Method: Composition-based stats.
Identities = 41/185 (22%), Positives = 73/185 (39%), Gaps = 13/185 (7%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDR--FASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+++GP G++ L + ++ F+ TR+ G DY V+ F
Sbjct 3 GTLFLIVGPSGVGKDTLLEGARDRLATSRWFSFPQRVVTRAADAG---GEDYIPVTPSEF 59
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
E +AAG F YG + V + +++G +L+ + R+ I
Sbjct 60 EQQLAAGAFWHQWHAHGLSYGIPMQ-VARDLDNGINVVLNASRNEIGAFRDKATHVVTIG 118
Query 597 I-APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNS-DLDKAYQE 654
I APP + L + G+ + E R + R +EQ + IVN +++
Sbjct 119 ISAPPGI--VEERLHERGRESEEEIKRRL---ARLVEQAPLTGYALEIVNDRTIEEGITA 173
Query 655 LLRLI 659
L+ LI
Sbjct 174 LVDLI 178
>sp|A8E0R9|GRIP2_XENLA Glutamate receptor-interacting protein
2 OS=Xenopus laevis OX=8355 GN=grip2 PE=2 SV=2
Length=1083
Score = 89.7 bits (221), Expect = 4e-17, Method: Composition-based stats.
Identities = 43/215 (20%), Positives = 80/215 (37%), Gaps = 13/215 (6%)
Query 240 ERVYESIGQYGGETVKIVRIEKARDIPLGATVRN---EMDSVIISRIVKGGAAEKSGLLH 296
+ + G + V +++ PLG T+ D ++IS + K G AE++G +H
Sbjct 651 DEDNSDEQETSGAIIYTVELKR-YGGPLGITISGTEEPFDPIVISGLTKRGLAERTGAIH 709
Query 297 EGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDY 356
GD +L IN I ++GK ++E LL T+T + + P ++ +
Sbjct 710 IGDRILAINNISLKGKPLSEAIHLLQMAGETVTLKIKKQTERIFPQRLSDSMNEGS---- 765
Query 357 DPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYRE----GDEDNQPLAGLVPGKSF 412
DP DD + LS + + W G + +
Sbjct 766 DPEDDLTDSQKTSKLSEIYSTTVPSVDSA-LESWDGSGIDAGYGSQGTYVPQAVGISLHP 824
Query 413 QQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKK 447
+ R + +++ E KS N++ +K
Sbjct 825 HEWRTSRQKSNTPPVEHRKSYPFLDGSFNEQDWEK 859
Score = 64.7 bits (156), Expect = 2e-09, Method: Composition-based stats.
Identities = 20/112 (18%), Positives = 44/112 (39%), Gaps = 9/112 (8%)
Query 226 KVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVR-----NEMDSVII 280
V E E +L P T + +T++I ++ ++ ++++
Sbjct 133 VVLEVEYELPPGTPDN----SSAIIPKTIEITLCKEGNSFGFVMRGGAHEDWHKSRALVV 188
Query 281 SRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ + GG A++ G L GD +L ++GI + + +L F +
Sbjct 189 TYVRPGGPADREGTLKVGDRLLCVDGISLHNITHTDALSILRQCSQEGVFQI 240
Score = 63.5 bits (153), Expect = 5e-09, Method: Composition-based stats.
Identities = 22/95 (23%), Positives = 41/95 (43%), Gaps = 3/95 (3%)
Query 257 VRIEKARDIPLGATV---RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
V++ K + + LG T+ R + +IIS I KG A ++G L GD++L I+ I +
Sbjct 570 VKLPKRKGVELGITISSSRKPGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDNCS 629
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVI 348
+ + +L + + + I
Sbjct 630 MEDAVQILRQCEDLVKLKIRKDEDNSDEQETSGAI 664
Score = 62.0 bits (149), Expect = 2e-08, Method: Composition-based stats.
Identities = 27/124 (22%), Positives = 46/124 (37%), Gaps = 9/124 (7%)
Query 225 DKVAEQEMQLEPITDERVYESIGQYGGE--TVKIVRIEKARDIPLGATVRNEMDS---VI 279
D + + D + E V IV + K LG T+ D
Sbjct 25 DGPYSKGNKDPAGNDLALVSRRQSIPEEFRGVTIVELIKKEGSTLGLTISGGTDKDGKPR 84
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
+S + GG A +S L+ GD + +NGI + E+ LL ++ + + + +
Sbjct 85 VSNLRPGGLAARSDQLNIGDYIKSVNGINLTKLRHEEIISLLKNVGERVVLEV----EYE 140
Query 340 PPPA 343
PP
Sbjct 141 LPPG 144
Score = 58.9 bits (141), Expect = 1e-07, Method: Composition-based stats.
Identities = 20/100 (20%), Positives = 40/100 (40%), Gaps = 4/100 (4%)
Query 256 IVRIEKARDIPLGATVRNEMDS----VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
+V I K LG ++ ++I ++ ++ G LH GD +L I+G
Sbjct 258 LVEIAKTPGSTLGISLSTGTHRNKQVIVIDKVKPASVVDRCGALHPGDHILSIDGTSTEH 317
Query 312 KDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVK 351
E LL+ + + ++P+ + P + V+
Sbjct 318 CTQMEATQLLASIIENVKLEILPAHHSRLPLRPPETVKVQ 357
Score = 53.9 bits (128), Expect = 4e-06, Method: Composition-based stats.
Identities = 21/72 (29%), Positives = 25/72 (35%), Gaps = 10/72 (14%)
Query 263 RDIPLGATVRNEMDSVI----------ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
R PL + I I AE+ GLL GD +L INGI
Sbjct 472 RGDPLNGFGIQLQGGIFATETLSSPPLIRFIEPDSPAERCGLLQVGDRLLSINGILTEDG 531
Query 313 DVNEVFDLLSDM 324
+ E LL D
Sbjct 532 TLEEANQLLRDA 543
Score = 42.7 bits (99), Expect = 0.014, Method: Composition-based stats.
Identities = 22/80 (28%), Positives = 33/80 (41%), Gaps = 1/80 (1%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
D + V ++ I GG A++SG L D++L++N + R D LL
Sbjct 983 TDDFGFSVSDGLLEKGVYVNMIRPGGPADRSG-LKTYDQILQVNHVRTRDFDCCLTVPLL 1041
Query 322 SDMHGTLTFVLIPSQQIKPP 341
SD L V+ IK
Sbjct 1042 SDAGDRLDLVISRGLSIKAE 1061
>sp|Q0U6X7|HSE1_PHANO Class E vacuolar protein-sorting machinery
protein HSE1 OS=Phaeosphaeria nodorum (strain SN15 / ATCC
MYA-4574 / FGSC 10173) OX=321614 GN=HSE1 PE=3 SV=1
Length=618
Score = 89.0 bits (219), Expect = 5e-17, Method: Composition-based stats.
Identities = 53/219 (24%), Positives = 92/219 (42%), Gaps = 38/219 (17%)
Query 310 RGKDVNEV-FDLLSDMHGTLTFVLIPSQQ-IKPPPAKETVIHVKAHFDYDPSDDPYVPCR 367
+G + + + + + P+ Q ++P TV V+A FD+ PS+
Sbjct 179 KGATPSAAKANAPQESNAGSSSQAAPAPQPVQPGTTAATVSRVRALFDFQPSEPGE---- 234
Query 368 ELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDK 427
L F+KGDI+ V+ +WW+ G+ G+ P ++ ++ ++ +E K
Sbjct 235 ---LQFKKGDIIAVLESVYKDWWKGSLRGNT------GIFPLNYVEKLQDPTREELE--K 283
Query 428 EPEKSGKLWCAKKNKKKRKKVLYN---ANKNDDYDNEEILTYEEMSLYHQP-ANRKRPII 483
E + +++ +N +K +L A D DNEEI LYH A R + I
Sbjct 284 EAQTEAEVFAQIRNVEKLLALLSTNTQAGGGDGRDNEEI-----TELYHSTLAIRPKLIE 338
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQE 522
LIG +++KD F ++RRD E
Sbjct 339 LIG------------KYSQKKDDFTQLNEKFIKARRDYE 365
>sp|B3PXI8|PHNN_RHIE6 Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Rhizobium etli (strain CIAT 652) OX=491916 GN=phnN PE=3
SV=1
Length=197
Score = 83.6 bits (205), Expect = 5e-17, Method: Composition-based stats.
Identities = 40/196 (20%), Positives = 74/196 (38%), Gaps = 13/196 (7%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRS--RRDQEVAGRDYHFVSR 533
A R ++++GP G++ L A H TR R + G D+ VS
Sbjct 11 AERGIMVVVVGPSGAGKDTLMNLAARHFS---GRADVHFTRRVITRHRGAGGEDHLSVSL 67
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
Q F A +G F E YG V ++ G I + + +L + + +
Sbjct 68 QGFAAMEQSGSFAVWWEAHGLKYGIP-AEVSVALSKGHIVVANGSRSALHRFQAAFPRLK 126
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTA-IVNS-DLDKA 651
+I + S E L L G+ + + + +D + NS +++A
Sbjct 127 VINVTA-SAEVLAGRLEARGRETHEDIMARL----ARGPLTVRGDYDVTELDNSGSIEEA 181
Query 652 YQELLRLINKLDTEPQ 667
Q+++ +++ L E
Sbjct 182 EQKMIAILDGLLAEVH 197
>sp|Q5F425|LIN7C_CHICK Protein lin-7 homolog C OS=Gallus gallus
OX=9031 GN=LIN7C PE=1 SV=1
Length=197
Score = 82.8 bits (203), Expect = 8e-17, Method: Composition-based stats.
Identities = 34/165 (21%), Positives = 74/165 (45%), Gaps = 14/165 (8%)
Query 185 NAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITD----- 239
A +L +++Q V ++ Q L +L + A+ ++ V E + + +
Sbjct 16 RAIELLEKLQRS-GEVPPQKLQALQRVLQSEFCNAVREVYEHVYE-TVDISSSPEVRANA 73
Query 240 --ERVYESIGQYGGETV-KIVRIEKARDIPLGA---TVRNEMDSVIISRIVKGGAAEKSG 293
+ + G + ++V + K + LG + + + ISRI+ GG A++ G
Sbjct 74 TAKATVAAFAASEGHSHPRVVELPK-TEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHG 132
Query 294 LLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
L GD++L +NG+ + G+ + +LL G + V+ + ++
Sbjct 133 GLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKV 177
>sp|Q792I0|LIN7C_RAT Protein lin-7 homolog C OS=Rattus norvegicus
OX=10116 GN=Lin7c PE=1 SV=1
Length=197
Score = 82.8 bits (203), Expect = 9e-17, Method: Composition-based stats.
Identities = 34/165 (21%), Positives = 74/165 (45%), Gaps = 14/165 (8%)
Query 185 NAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITD----- 239
A +L +++Q V ++ Q L +L + A+ ++ V E + + +
Sbjct 16 RAIELLEKLQRS-GEVPPQKLQALQRVLQSEFCNAVREVYEHVYE-TVDISSSPEVRANA 73
Query 240 --ERVYESIGQYGGETV-KIVRIEKARDIPLGA---TVRNEMDSVIISRIVKGGAAEKSG 293
+ + G + ++V + K + LG + + + ISRI+ GG A++ G
Sbjct 74 TAKATVAAFAASEGHSHPRVVELPK-TEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHG 132
Query 294 LLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
L GD++L +NG+ + G+ + +LL G + V+ + ++
Sbjct 133 GLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKV 177
>sp|Q5RAA5|LIN7C_PONAB Protein lin-7 homolog C OS=Pongo abelii
OX=9601 GN=LIN7C PE=2 SV=1
Length=197
Score = 82.8 bits (203), Expect = 9e-17, Method: Composition-based stats.
Identities = 34/165 (21%), Positives = 74/165 (45%), Gaps = 14/165 (8%)
Query 185 NAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITD----- 239
A +L +++Q V ++ Q L +L + A+ ++ V E + + +
Sbjct 16 RAIELLEKLQRS-GEVPPQKLQALQRVLQSEFCNAVREVYEHVYE-TVDISSSPEVRANA 73
Query 240 --ERVYESIGQYGGETV-KIVRIEKARDIPLGA---TVRNEMDSVIISRIVKGGAAEKSG 293
+ + G + ++V + K + LG + + + ISRI+ GG A++ G
Sbjct 74 TAKATVAAFAASEGHSHPRVVELPK-TEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHG 132
Query 294 LLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
L GD++L +NG+ + G+ + +LL G + V+ + ++
Sbjct 133 GLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKV 177
>sp|O88952|LIN7C_MOUSE Protein lin-7 homolog C OS=Mus musculus
OX=10090 GN=Lin7c PE=1 SV=2
Length=197
Score = 82.8 bits (203), Expect = 9e-17, Method: Composition-based stats.
Identities = 34/165 (21%), Positives = 74/165 (45%), Gaps = 14/165 (8%)
Query 185 NAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITD----- 239
A +L +++Q V ++ Q L +L + A+ ++ V E + + +
Sbjct 16 RAIELLEKLQRS-GEVPPQKLQALQRVLQSEFCNAVREVYEHVYE-TVDISSSPEVRANA 73
Query 240 --ERVYESIGQYGGETV-KIVRIEKARDIPLGA---TVRNEMDSVIISRIVKGGAAEKSG 293
+ + G + ++V + K + LG + + + ISRI+ GG A++ G
Sbjct 74 TAKATVAAFAASEGHSHPRVVELPK-TEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHG 132
Query 294 LLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
L GD++L +NG+ + G+ + +LL G + V+ + ++
Sbjct 133 GLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKV 177
>sp|Q9NUP9|LIN7C_HUMAN Protein lin-7 homolog C OS=Homo sapiens
OX=9606 GN=LIN7C PE=1 SV=1
Length=197
Score = 82.8 bits (203), Expect = 9e-17, Method: Composition-based stats.
Identities = 34/165 (21%), Positives = 74/165 (45%), Gaps = 14/165 (8%)
Query 185 NAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITD----- 239
A +L +++Q V ++ Q L +L + A+ ++ V E + + +
Sbjct 16 RAIELLEKLQRS-GEVPPQKLQALQRVLQSEFCNAVREVYEHVYE-TVDISSSPEVRANA 73
Query 240 --ERVYESIGQYGGETV-KIVRIEKARDIPLGA---TVRNEMDSVIISRIVKGGAAEKSG 293
+ + G + ++V + K + LG + + + ISRI+ GG A++ G
Sbjct 74 TAKATVAAFAASEGHSHPRVVELPK-TEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHG 132
Query 294 LLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
L GD++L +NG+ + G+ + +LL G + V+ + ++
Sbjct 133 GLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKV 177
>sp|Q0P5F3|LIN7C_BOVIN Protein lin-7 homolog C OS=Bos taurus OX=9913
GN=LIN7C PE=2 SV=1
Length=197
Score = 82.8 bits (203), Expect = 9e-17, Method: Composition-based stats.
Identities = 34/165 (21%), Positives = 74/165 (45%), Gaps = 14/165 (8%)
Query 185 NAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITD----- 239
A +L +++Q V ++ Q L +L + A+ ++ V E + + +
Sbjct 16 RAIELLEKLQRS-GEVPPQKLQALQRVLQSEFCNAVREVYEHVYE-TVDISSSPEVRANA 73
Query 240 --ERVYESIGQYGGETV-KIVRIEKARDIPLGA---TVRNEMDSVIISRIVKGGAAEKSG 293
+ + G + ++V + K + LG + + + ISRI+ GG A++ G
Sbjct 74 TAKATVAAFAASEGHSHPRVVELPK-TEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHG 132
Query 294 LLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
L GD++L +NG+ + G+ + +LL G + V+ + ++
Sbjct 133 GLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKV 177
>sp|E1SHE4|PHNN_PANVC Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Pantoea vagans (strain C9-1) OX=712898 GN=phnN PE=3 SV=1
Length=178
Score = 81.3 bits (199), Expect = 2e-16, Method: Composition-based stats.
Identities = 36/190 (19%), Positives = 67/190 (35%), Gaps = 26/190 (14%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
R I L GP G++ L L R A + TR+ G ++ ++ F+
Sbjct 3 RLIWLTGPSGSGKDSLLDALRAAPPPRLLIAHRYITRAADAG---GENHVALTETEFDRR 59
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF--- 596
A G F E YG ++ Q + G+ + + L + + F
Sbjct 60 AALGLFAVSWEAHGFRYGIGCET-EQWLLRGQNVV----VNGSR-LHLAQAQAR--FGSQ 111
Query 597 IAPPSQE----RLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD--LDK 650
+ P + L A L + G+ + E R + + I+N+D L +
Sbjct 112 LLPVCLQVTPAVLAARLRQRGREDEAEIARRLARAAQPQPDGC------LILNNDGALAE 165
Query 651 AYQELLRLIN 660
+L +++
Sbjct 166 TVCQLRQILE 175
>sp|Q3SGK8|PHNN_THIDA Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Thiobacillus denitrificans (strain ATCC 25259) OX=292415
GN=phnN PE=3 SV=1
Length=190
Score = 81.3 bits (199), Expect = 2e-16, Method: Composition-based stats.
Identities = 39/199 (20%), Positives = 74/199 (37%), Gaps = 27/199 (14%)
Query 479 KRPIILIGPQNCGQNEL----RQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
+ +IGP G++ L R+RL FA R E+ G ++ ++
Sbjct 4 GKLFYVIGPSGSGKDSLMRYGRERLAGDPGVVFAH-----RYITRPVELHGENHVALTED 58
Query 535 AFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK------TLRNS 588
F+A +A G F H + YG + + + G +L + R
Sbjct 59 EFDARLATGLFALHWDSHGLRYGIGRE-INLWLAKGCNVVL----NGSREYLPEARRRYP 113
Query 589 DLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNS-D 647
L ++ ++P E L L G+ + + R + + ++ G I N +
Sbjct 114 GLTAILVNVSP---EVLAERLRARGRETEDQISRRV-ARAKQFMHPEGRL--EVIANDAE 167
Query 648 LDKAYQELLRLINKLDTEP 666
L A + L++L++ D
Sbjct 168 LHVAGERLVQLLSDADASK 186
>sp|Q9BXL6|CAR14_HUMAN Caspase recruitment domain-containing protein
14 OS=Homo sapiens OX=9606 GN=CARD14 PE=1 SV=2
Length=1004
Score = 86.3 bits (212), Expect = 4e-16, Method: Composition-based stats.
Identities = 109/690 (16%), Positives = 218/690 (32%), Gaps = 121/690 (18%)
Query 51 RRSAQLERIRQQQE-DMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEG 109
R SAQ E + E D RR+ E Q +L + +R +L PP E
Sbjct 368 RDSAQREISQSLVEKDSLRRQVFELTDQVCELRTQLR--QLQAEPPGV------LKQEAR 419
Query 110 IVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAI 169
P +++ + H + + L+ +++ + +
Sbjct 420 TREPCPREKQRLVRM-----------HAI--CPRDDSDCSLVSSTESQLLSDLSATSSRE 466
Query 170 TVHMNKASPPFPLISNA--QDLAQEVQTV-------LKPVHHKEGQELTALLNTPHIQAL 220
V ++S P P + + +A++ L+ G A PH+
Sbjct 467 LVDSFRSSSPAPPSQQSLYKRVAEDFGEEPWSFSSCLEIPEGDPGALPGAKAGDPHLDYE 526
Query 221 LLAHDKVAEQEMQLEPITDERVYESIGQYGGE---------TVKIVRIEKARDIPLGATV 271
LL + + E L+P++ R+ S V ++ + + + +
Sbjct 527 LLDTADLPQLESSLQPVSPGRLDVSESGVLMRRRPARRILSQVTMLAFQGDALLEQISVI 586
Query 272 RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEIN--------GIEIRGKDVNEVFDLLSD 323
+ + I R+ G AA++ L G +++ ++ + + E LL
Sbjct 587 GGNLTGIFIHRVTPGSAADQM-ALRPGTQIVMVDYEASEPLFKAVLEDTTLEEAVGLLRR 645
Query 324 MHGTLTFVLIPSQQ---------IKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQ 374
+ G + + +++ + + L
Sbjct 646 VDGFCCLSVKVNTDGYKRLLQDLEAKVATSGDSFYIRVNLAMEGRAKGE-------LQVH 698
Query 375 KGDILHVISQ--EDPNWWQAYREGDEDNQPLA--GLVPGKSF-QQQREAMKQTI------ 423
++LHV + W A+R + A G +P S QQQ A+ Q +
Sbjct 699 CNEVLHVTDTMFQGCGCWHAHRVNSYTMKDTAAHGTIPNYSRAQQQLIALIQDMTQQCTV 758
Query 424 ---EEDKEPEKSGKLWCAKKNK---------KKRKKVLYNANKNDDYDNEEILTYEEMSL 471
P+K ++ K K + + + + E LT +L
Sbjct 759 TRKPSSGGPQKLVRIVSMDKAKASPLRLSFDRGQLDPSRMEGSSTCFWAESCLTLVPYTL 818
Query 472 YHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFV 531
+ +L+ P+ G+ L ++L F + ++
Sbjct 819 VRPHRPARPRPVLLVPRAVGK-ILSEKLC--LLQGFKKCLAE----------------YL 859
Query 532 SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK 591
S++ +EA G I+ GE + +V ++ LL ++ S+ TL D+
Sbjct 860 SQEEYEAWSQRGDIIQEGEVSGGRCWVTRHAVESLMEKNTHALLDVQLDSVCTLHRMDIF 919
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREME---QNNGHYF-----DTAI 643
P +I + S A K+G +++E R+ E + D
Sbjct 920 PIVIHV---SVNEKMAKKLKKGLQRLGTSEEQLLEAARQEEGDLDRAPCLYSSLAPDGW- 975
Query 644 VNSDLDKAYQELLRLINKLDTEPQWVPSTW 673
SDLD + + I + W +
Sbjct 976 --SDLDGLLSCVRQAIADEQKKVVWTEQSP 1003
>sp|Q1GL02|PHNN_RUEST Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Ruegeria sp. (strain TM1040) OX=292414 GN=phnN PE=3 SV=1
Length=190
Score = 79.7 bits (195), Expect = 7e-16, Method: Composition-based stats.
Identities = 48/200 (24%), Positives = 72/200 (36%), Gaps = 16/200 (8%)
Query 469 MSLYHQPANRKRPII-LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRD 527
MS+ + K P+I ++GP G++ L L + R S TR+ G D
Sbjct 1 MSVPADTSPAKGPVIAVVGPSGVGKDSLMSGLAVADP-RLRSMRRVITRAPEAG---GED 56
Query 528 YHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN 587
Y VS F+A + A F H YG D + ++ L++L L +
Sbjct 57 YQPVSEAEFQALVEADVFALHWNAHGLRYGIPRD-IEKLREGATGVLVNLSRAVLLQAQE 115
Query 588 SDLKPYIIFIAP-PSQERLRALLAKEGKNPKPEELREIIEKTREME--QNNGHYFDTAIV 644
+I + P E L A LA G+ E R + + + H D
Sbjct 116 VFDDFRVISVTARP--EVLAARLAGRGREDAAEVERRLARASLALPEGLRQVHEVD---- 169
Query 645 NS-DLDKAYQELLRLINKLD 663
NS L A E +I
Sbjct 170 NSGALSAAIVEAQAIIQAER 189
>sp|A6V255|PHNN_PSEA7 Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Pseudomonas aeruginosa (strain PA7) OX=381754 GN=phnN
PE=3 SV=1
Length=185
Score = 79.7 bits (195), Expect = 7e-16, Method: Composition-based stats.
Identities = 37/186 (20%), Positives = 55/186 (30%), Gaps = 19/186 (10%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
R I L+GP G++ L Q +E R E G D V+ F+
Sbjct 3 GRLIYLMGPSGSGKDSLLQA--AREPLALRGCRIVRRVITRSAEAVGEDAQAVTPAQFDT 60
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK----TLRNSDLKPYI 594
A F YG + + + + G L + R
Sbjct 61 LERASAFAMSWRANGLCYGIPVQ-IDEWLAQGYDVL----VNGSRGYLAQARRRYPDLLA 115
Query 595 IF--IAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNS-DLDKA 651
+ + P E LR L G+ E + G F + NS +LD
Sbjct 116 VLLGVQP---EVLRQRLLARGRESPEEIEARLARNAEFAAGLEGPLF--QLDNSGELDDT 170
Query 652 YQELLR 657
+ LL
Sbjct 171 VRALLA 176
>sp|Q89V30|PHNN_BRADU Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC
13528 / IAM 13628 / NBRC 14792 / USDA 110) OX=224911 GN=phnN
PE=3 SV=1
Length=198
Score = 79.7 bits (195), Expect = 9e-16, Method: Composition-based stats.
Identities = 31/168 (18%), Positives = 62/168 (37%), Gaps = 10/168 (6%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
R ++++GP G++ L Q + + V R + A D +S F
Sbjct 18 GRLVLVVGPSGAGKDTLLQ--LAQAACIDDHDVVFPRRVVTRESSAAEDNIAMSPDEFRR 75
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI- 597
I G F H + + Y ++ + I +G+ ++++ + LR + ++ I
Sbjct 76 GIDHGDFAVHWDAHGHSYALPLE-INDDIRAGRAVVVNVSRTVIAALRQAYANVVVVAIT 134
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVN 645
APP + L LA ++ + + D I+N
Sbjct 135 APP--DVLAQRLAARARHSDGNIAERLSRSVEDASAQA----DVTILN 176
>sp|A1A5G4|MAGI3_XENTR Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 3 OS=Xenopus tropicalis
OX=8364 GN=magi3 PE=2 SV=1
Length=1107
Score = 83.2 bits (204), Expect = 5e-15, Method: Composition-based stats.
Identities = 31/100 (31%), Positives = 47/100 (47%), Gaps = 14/100 (14%)
Query 492 QNELRQRLMN-KEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGE 550
+ + +L + + +P TTRS RD EV G DY+F+S + F+A +G +E G
Sbjct 119 KGSIDHKLQQVIRDNLYLRTIPCTTRSPRDGEVPGVDYNFISVEQFKALEDSGVLLESGT 178
Query 551 FEKNLYGTSI----------DSVRQVINSGKICLLSLRTQ 580
++ N YGT D V QV+ G+ TQ
Sbjct 179 YDGNFYGTPKPPAEPNPFQADPVDQVLFDGE---FDTETQ 215
Score = 67.4 bits (163), Expect = 4e-10, Method: Composition-based stats.
Identities = 26/134 (19%), Positives = 53/134 (40%), Gaps = 15/134 (11%)
Query 228 AEQEMQLEPITDERVY-------ESIGQYGGETVKIVRIEKARDIPLGATV----RNEMD 276
E+E+Q P +I + E ++ +++ + G +
Sbjct 819 EEEELQHTPPAHNGSPRLNRIEVSAIPKLPAEAYDVI-LQRKDNEGFGFVILTSKNKPPP 877
Query 277 SVI---ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
VI I R+++G A++ L GD + +NG I + + L+ D T+T +I
Sbjct 878 GVIPHKIGRVIEGSPADRCRKLKVGDRISAVNGQSIVELSHDNIVQLIKDAGNTVTLTVI 937
Query 334 PSQQIKPPPAKETV 347
++ + PP+
Sbjct 938 AEEEHRGPPSGSNS 951
Score = 59.3 bits (142), Expect = 9e-08, Method: Composition-based stats.
Identities = 21/88 (24%), Positives = 39/88 (44%), Gaps = 4/88 (5%)
Query 257 VRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
V +E+ G ++R + + I R+ + G A K G +H GD+++EIN +G
Sbjct 1004 VELERG-PRGFGFSLRGGKEYNMGLFILRLAEDGPAIKDGRIHVGDQIVEINNEPTQGIT 1062
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
+L+ + +L P + P
Sbjct 1063 HTRAIELIQAGGSKVLLLLRPGTGLIPD 1090
Score = 56.6 bits (135), Expect = 7e-07, Method: Composition-based stats.
Identities = 35/160 (22%), Positives = 62/160 (39%), Gaps = 10/160 (6%)
Query 257 VRIEKARDIPLG---ATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
V + K ++ G ++ I I+ GAAEK G L DE++ I+G+ ++GK
Sbjct 728 VFLRK-QESGFGFRVLGGDGPDQAIYIGAIIPLGAAEKDGRLRAADELICIDGVPVKGKS 786
Query 314 VNEVFDLLSDM--HGTLTFVLIPSQQIKPPPAKETVIHVKAHFDY-DPSDDPYVPCRELG 370
+V DL+++ +G + + +E + P +
Sbjct 787 HKQVLDLMTNAARNGHVLLTVRRQIYYTDKQQEEEELQHTPPAHNGSPRLNRIEVSAIPK 846
Query 371 LSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
L + D VI Q N + N+P G++P K
Sbjct 847 LPAEAYD---VILQRKDNEGFGFVILTSKNKPPPGVIPHK 883
Score = 48.9 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 17/86 (20%), Positives = 34/86 (40%), Gaps = 5/86 (6%)
Query 261 KARDIPLGATV-RNEMDSVI--ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
K + G T+ + + ++K G A + G + GD +++ING + G EV
Sbjct 411 KKSAMGFGFTIIGGDRPDEFLQVKNVLKDGPAAQDGKIAPGDVIVDINGTCVLGHTHAEV 470
Query 318 FDL--LSDMHGTLTFVLIPSQQIKPP 341
+ L ++ + L +
Sbjct 471 VQMFQLIPINQYVNMTLCRGYPLPED 496
Score = 36.2 bits (82), Expect = 1.4, Method: Composition-based stats.
Identities = 37/221 (17%), Positives = 68/221 (31%), Gaps = 34/221 (15%)
Query 245 SIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEI 304
+ GG+ ++ I + + + + V S IV ++ GD +LE+
Sbjct 19 GLSGVGGDPCSLLEIRGGAEHGEFPYLGRQREDV-ASFIVGKVPSQ-------GDVLLEV 70
Query 305 NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYV 364
NG + G + ++ + K + K Y
Sbjct 71 NGTPVSGLTHRDTLAVIRHFREPIRLK----------TVKPGKVINKDLRHY-------- 112
Query 365 PCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSF----QQQREAMK 420
L L FQKG I H + Q + P G VPG + +Q +A++
Sbjct 113 ----LSLQFQKGSIDHKLQQVIRDNLYLRTIPCTTRSPRDGEVPGVDYNFISVEQFKALE 168
Query 421 QTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNE 461
+ + G + K + + +D E
Sbjct 169 DSGVLLESGTYDGNFYGTPKPPAEPNPFQADPVDQVLFDGE 209
>sp|Q9Y3R0|GRIP1_HUMAN Glutamate receptor-interacting protein
1 OS=Homo sapiens OX=9606 GN=GRIP1 PE=1 SV=3
Length=1128
Score = 82.8 bits (203), Expect = 6e-15, Method: Composition-based stats.
Identities = 32/114 (28%), Positives = 54/114 (47%), Gaps = 5/114 (4%)
Query 261 KARDIPLGATVRN---EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
K PLG T+ D +IIS + KGG AE++G +H GD +L IN ++GK ++E
Sbjct 677 KRYGGPLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEA 736
Query 318 FDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHF-DYDPSDDPYVPCRELG 370
LL T+T + + + + + +H D ++ P ++ G
Sbjct 737 IHLLQMAGETVTLKIKKQTDAQSASSPK-KFPISSHLSDLGDVEEDSSPAQKPG 789
Score = 63.2 bits (152), Expect = 7e-09, Method: Composition-based stats.
Identities = 23/112 (21%), Positives = 44/112 (39%), Gaps = 10/112 (9%)
Query 226 KVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV-----RNEMDSVII 280
V E E +L P++ TV++ ++ RN+ V+I
Sbjct 128 VVLEVEYELPPVS-----VQGSSVIFRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRPVVI 182
Query 281 SRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ + GG A++ G + GD +L ++GI + G E +L ++
Sbjct 183 TCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEAALLI 234
Score = 62.0 bits (149), Expect = 2e-08, Method: Composition-based stats.
Identities = 31/175 (18%), Positives = 58/175 (33%), Gaps = 27/175 (15%)
Query 221 LLAHDKVAEQEMQLEPITDERVYESIGQYGGE--TVKIVRIEKARDIPLGATVRNEMDS- 277
L + + D + E +V + K LG TV +D
Sbjct 16 LTKDESPYTKSASQTKPPDGALAVRRQSIPEEFKGSTVVELMKKEGTTLGLTVSGGIDKD 75
Query 278 --VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+S + +GG A +S L GD + +NGI + +E+ LL ++ + +
Sbjct 76 GKPRVSNLRQGGIAARSDQLDVGDYIKAVNGINLAKFRHDEIISLLKNVGERVVLEV--E 133
Query 336 QQIKPPPAKETVIHVK--------------------AHFDYDPSDDPYVPCRELG 370
++ P + + + + AH D + S + C G
Sbjct 134 YELPPVSVQGSSVIFRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPG 188
Score = 61.2 bits (147), Expect = 2e-08, Method: Composition-based stats.
Identities = 22/97 (23%), Positives = 41/97 (42%), Gaps = 5/97 (5%)
Query 257 VRIEKARDIPLGATV-----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
V++ K ++ LG T+ R D ++IS I KG A ++G L GD++L I+ I +
Sbjct 574 VKLPKKHNVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDN 633
Query 312 KDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVI 348
+ + +L + + + I
Sbjct 634 CSMEDAVQILQQCEDLVKLKIRKDEDNSDEQESSGAI 670
Score = 57.4 bits (137), Expect = 4e-07, Method: Composition-based stats.
Identities = 19/90 (21%), Positives = 37/90 (41%), Gaps = 4/90 (4%)
Query 256 IVRIEKARDIPLGATVRN----EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
+V + K LG + ++I +I A++ G LH GD +L I+G +
Sbjct 252 LVEVAKTPGASLGVALTTSMCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTSMEY 311
Query 312 KDVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
+ E L++ + ++P Q +
Sbjct 312 CTLAEATQFLANTTDQVKLEILPHHQTRLA 341
Score = 55.1 bits (131), Expect = 2e-06, Method: Composition-based stats.
Identities = 23/74 (31%), Positives = 28/74 (38%), Gaps = 1/74 (1%)
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
+IS I AE+ G+L GD V+ INGI E LL D T L +
Sbjct 502 LISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEEASQLLRDSSITSKVTLEIEFDV 561
Query 339 KPPPA-KETVIHVK 351
HVK
Sbjct 562 AESVIPSSGTFHVK 575
Score = 42.4 bits (98), Expect = 0.018, Method: Composition-based stats.
Identities = 22/124 (18%), Positives = 46/124 (37%), Gaps = 4/124 (3%)
Query 227 VAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEM--DSVIISRIV 284
V + + L + E + E + E K+ + + G +V + + V + I
Sbjct 977 VGRKSVTLRKMKQE-IKEIMSPTPVELHKVTLYKDSDMEDFGFSVADGLLEKGVYVKNIR 1035
Query 285 KGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAK 344
G + G L D +L++N + R D V L+++ L V+ +
Sbjct 1036 PAGPGDL-GGLKPYDRLLQVNHVRTRDFDCCLVVPLIAESGNKLDLVISRNPLASQKSID 1094
Query 345 ETVI 348
+ +
Sbjct 1095 QQSL 1098
>sp|D0KG93|PHNN_PECPW Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Pectobacterium parmentieri (strain WPP163) OX=561231 GN=phnN
PE=3 SV=1
Length=188
Score = 77.0 bits (188), Expect = 6e-15, Method: Composition-based stats.
Identities = 31/186 (17%), Positives = 61/186 (33%), Gaps = 17/186 (9%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
+ I LIGP G++ L + + A + TR E+ G ++ ++ + F
Sbjct 3 KLIYLIGPSGAGKDSLLRAIRQLSLPHLLVAHRYITR---PAEIQGENHIALTPEEFAIR 59
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK----TLRNSDLKPYII 595
G F + + + YG I+ + + G + + R
Sbjct 60 QQLGIFALNWQAHQCHYGIGIE-IDYWLQRGSDVI----VNGSRAYLTQARERYGNTLFP 114
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNS--DLDKAYQ 653
S+ LR L G+ + + + E + D ++N+ DL
Sbjct 115 ICLTVSESALRQRLRARGRESEQQIAMRLQRAEEEQNRLQS---DCVLLNNDGDLQHTLS 171
Query 654 ELLRLI 659
L+
Sbjct 172 TFQSLL 177
>sp|Q9JK71|MAGI3_RAT Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 3 OS=Rattus norvegicus OX=10116
GN=Magi3 PE=1 SV=2
Length=1470
Score = 82.4 bits (202), Expect = 8e-15, Method: Composition-based stats.
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
Query 492 QNELRQRLMN-KEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGE 550
+ + +L + + +P TTR+ RD EV G DY+F+S + F+A +G +E G
Sbjct 125 KGSIDHKLQQVIRDNLYLITIPCTTRAPRDGEVPGVDYNFISVEQFKALEESGALLESGT 184
Query 551 FEKNLYGTSIDSVR 564
++ N YGT
Sbjct 185 YDGNFYGTPKPPAE 198
Score = 66.2 bits (160), Expect = 7e-10, Method: Composition-based stats.
Identities = 39/248 (16%), Positives = 84/248 (34%), Gaps = 28/248 (11%)
Query 190 AQEVQTV----LKPVHHKEGQELTALLNTPHIQALLLAHDKV----------AEQEMQLE 235
A E+ + +K HK+ +L + LL K+ + Q
Sbjct 773 ADELMCIDGIPVKGKSHKQVLDLMTT-AARNGHVLLTVRRKIFYGEKQPEDESPQAFSQS 831
Query 236 PITDERVYESIGQYGGETVKIVRIEKARDIPLGATV----RNEMDSVI---ISRIVKGGA 288
E + + V +++ + G + VI I R++ G
Sbjct 832 GSPRLNRTELPTRSAPQESYDVILQRKENEGFGFVILTSKSKPPPGVIPHKIGRVIDGSP 891
Query 289 AEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVI 348
A++ G L GD + +NG I + + L+ D T+T ++ ++ PP+
Sbjct 892 ADRCGRLKVGDHISAVNGQSIVDLSHDNIVQLIKDAGVTVTLTVVAEEEHHGPPSGTNSA 951
Query 349 HVKAHFDYDP---SDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAG 405
+ P + ++P L G++ + + W ++ + + +
Sbjct 952 RQSPALQHRPMGQAQATHIPGDRTALE---GEVGKDVCSSYRHSWSDHKHLAQPDTAVIS 1008
Query 406 LVPGKSFQ 413
+V + Q
Sbjct 1009 VVGSRHSQ 1016
Score = 64.3 bits (155), Expect = 3e-09, Method: Composition-based stats.
Identities = 32/161 (20%), Positives = 60/161 (37%), Gaps = 12/161 (7%)
Query 217 IQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD 276
+ H +A+ + + + R +S+G Y E + R E +
Sbjct 989 YRHSWSDHKHLAQPDTAVISVVGSRHSQSLGCYPVELER-----GPRGFGFSLRGGKEYN 1043
Query 277 -SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ I R+ + G A K G +H GD+++EING +G +L+ + +L P
Sbjct 1044 MGLFILRLAEDGPAIKDGRIHVGDQIVEINGEPTQGITHTRAIELIQAGGNKVLLLLRPG 1103
Query 336 QQIKPPPAKETVIHVKA---HFDYDPSDDPYVPCRELGLSF 373
+ P + + +D P P +P +F
Sbjct 1104 TGLIPDHGDWDIYSPSSSNVIYDEQP---PPLPSSHSAATF 1141
Score = 54.3 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 24/96 (25%), Positives = 42/96 (44%), Gaps = 6/96 (6%)
Query 257 VRIEKARDIPLGA---TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
V + K ++ G S+ I I+ GAAEK G L DE++ I+GI ++GK
Sbjct 730 VFLRK-QESGFGFRVLGGDGPDQSIYIGAIIPLGAAEKDGRLRAADELMCIDGIPVKGKS 788
Query 314 VNEVFDLLSDM--HGTLTFVLIPSQQIKPPPAKETV 347
+V DL++ +G + + ++
Sbjct 789 HKQVLDLMTTAARNGHVLLTVRRKIFYGEKQPEDES 824
Score = 44.7 bits (104), Expect = 0.003, Method: Composition-based stats.
Identities = 16/81 (20%), Positives = 33/81 (41%), Gaps = 5/81 (6%)
Query 261 KARDIPLGATV-RNEMDSVI--ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
K + G T+ + + ++K G A + G + GD +++ING + G +V
Sbjct 417 KKSTMGFGFTIIGGDRPDEFLQVKNVLKDGPAAQDGKMAPGDVIVDINGNCVLGHTHADV 476
Query 318 FDL--LSDMHGTLTFVLIPSQ 336
+ L ++ + L
Sbjct 477 VQMFQLVPVNQYVNLTLCRGY 497
>sp|Q9EQJ9|MAGI3_MOUSE Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 3 OS=Mus musculus OX=10090
GN=Magi3 PE=1 SV=2
Length=1476
Score = 82.0 bits (201), Expect = 1e-14, Method: Composition-based stats.
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
Query 492 QNELRQRLMN-KEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGE 550
+ + +L + + +P TTR+ RD EV G DY+F+S + F+A +G +E G
Sbjct 125 KGSIDHKLQQVIRDNLYLRTIPCTTRAPRDGEVPGVDYNFISVEQFKALEESGALLESGT 184
Query 551 FEKNLYGTSIDSVR 564
++ N YGT
Sbjct 185 YDGNFYGTPKPPAE 198
Score = 67.0 bits (162), Expect = 5e-10, Method: Composition-based stats.
Identities = 40/248 (16%), Positives = 85/248 (34%), Gaps = 28/248 (11%)
Query 190 AQEVQTV----LKPVHHKEGQELTALLNTPHIQALLLAHDKV----------AEQEMQLE 235
A E+ + +K HK+ +L + LL K+ + Q
Sbjct 773 ADELMCIDGIPVKGKSHKQVLDLMTT-AARNGHVLLTVRRKIFYGEKQPEDESHQAFSQN 831
Query 236 PITDERVYESIGQYGGETVKIVRIEKARDIPLGATV----RNEMDSVI---ISRIVKGGA 288
E + + V +++ + G + VI I R++ G
Sbjct 832 GSPRLNRAELPTRSAPQEAYDVTLQRKENEGFGFVILTSKSKPPPGVIPHKIGRVIDGSP 891
Query 289 AEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVI 348
A++ G L GD + +NG I + + L+ D T+T ++ ++ PP+
Sbjct 892 ADRCGGLKVGDHISAVNGQSIVDLSHDNIVQLIKDAGVTVTLTVVAEEEHHGPPSGTNSA 951
Query 349 HVKAHFDYDP---SDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAG 405
+ P + ++P + L G+I + + W ++ + + +
Sbjct 952 RQSPALQHRPMGQAQANHIPGDRIALE---GEIGRDVCSSYRHSWSDHKHLAQPDTAVIS 1008
Query 406 LVPGKSFQ 413
+V + Q
Sbjct 1009 VVGSRHNQ 1016
Score = 63.5 bits (153), Expect = 6e-09, Method: Composition-based stats.
Identities = 32/161 (20%), Positives = 58/161 (36%), Gaps = 12/161 (7%)
Query 217 IQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD 276
+ H +A+ + + + R +S+G Y E + R E +
Sbjct 989 YRHSWSDHKHLAQPDTAVISVVGSRHNQSLGCYPVELER-----GPRGFGFSLRGGKEYN 1043
Query 277 -SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ I R+ + G A K G +H GD+++EING +G +L+ + +L P
Sbjct 1044 MGLFILRLAEDGPAIKDGRIHVGDQIVEINGEPTQGITHTRAIELIQAGGNKVLLLLRPG 1103
Query 336 QQIKPPPAKETV---IHVKAHFDYDPSDDPYVPCRELGLSF 373
+ P +D P P +P +F
Sbjct 1104 TGLIPDHGDWDTNSPSSSNVIYDEQP---PPLPSSHSASTF 1141
Score = 54.3 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 24/96 (25%), Positives = 42/96 (44%), Gaps = 6/96 (6%)
Query 257 VRIEKARDIPLGA---TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
V + K ++ G S+ I I+ GAAEK G L DE++ I+GI ++GK
Sbjct 730 VFLRK-QESGFGFRVLGGDGPDQSIYIGAIIPLGAAEKDGRLRAADELMCIDGIPVKGKS 788
Query 314 VNEVFDLLSDM--HGTLTFVLIPSQQIKPPPAKETV 347
+V DL++ +G + + ++
Sbjct 789 HKQVLDLMTTAARNGHVLLTVRRKIFYGEKQPEDES 824
Score = 45.8 bits (107), Expect = 0.002, Method: Composition-based stats.
Identities = 16/86 (19%), Positives = 34/86 (40%), Gaps = 5/86 (6%)
Query 261 KARDIPLGATV-RNEMDSVI--ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
K + G T+ + + ++K G A + G + GD +++ING + G +V
Sbjct 417 KKSTMGFGFTIIGGDRPDEFLQVKNVLKDGPAAQDGKIAPGDVIVDINGNCVLGHTHADV 476
Query 318 FDL--LSDMHGTLTFVLIPSQQIKPP 341
+ L ++ + L +
Sbjct 477 VQMFQLVPVNQYVNLTLCRGYPLPDD 502
>sp|P97879|GRIP1_RAT Glutamate receptor-interacting protein 1
OS=Rattus norvegicus OX=10116 GN=Grip1 PE=1 SV=1
Length=1112
Score = 81.6 bits (200), Expect = 1e-14, Method: Composition-based stats.
Identities = 33/114 (29%), Positives = 55/114 (48%), Gaps = 5/114 (4%)
Query 261 KARDIPLGATVRN---EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
K PLG T+ D +IIS + KGG AE++G +H GD +L IN ++GK ++E
Sbjct 676 KRYGGPLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEA 735
Query 318 FDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAH-FDYDPSDDPYVPCRELG 370
LL T+T + +P + + + + +H D ++ P + G
Sbjct 736 IHLLQMAGETVTLKIKKQTDAQPASSPK-KLPIPSHSSDLGDGEEDPSPIQRPG 788
Score = 65.5 bits (158), Expect = 1e-09, Method: Composition-based stats.
Identities = 24/112 (21%), Positives = 45/112 (40%), Gaps = 10/112 (9%)
Query 226 KVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV-----RNEMDSVII 280
V E E +L P++ TV++ ++ RN+ V+I
Sbjct 128 VVLEVEYELPPVS-----IQGSSVMFRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRPVVI 182
Query 281 SRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ + GG A++ G + GD +L ++GI + G E +L T ++
Sbjct 183 TCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLI 234
Score = 62.0 bits (149), Expect = 2e-08, Method: Composition-based stats.
Identities = 31/175 (18%), Positives = 58/175 (33%), Gaps = 27/175 (15%)
Query 221 LLAHDKVAEQEMQLEPITDERVYESIGQYGGE--TVKIVRIEKARDIPLGATVRNEMDS- 277
L + + D + E +V + K LG TV +D
Sbjct 16 LTKDESPYTKSASQTKPPDGALAVRRQSIPEEFKGSTVVELMKKEGTTLGLTVSGGIDKD 75
Query 278 --VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+S + +GG A +S L GD + +NGI + +E+ LL ++ + +
Sbjct 76 GKPRVSNLRQGGIAARSDQLDVGDYIKAVNGINLAKFRHDEIISLLKNVGERVVLEV--E 133
Query 336 QQIKPPPAKETVIHVK--------------------AHFDYDPSDDPYVPCRELG 370
++ P + + + + AH D + S + C G
Sbjct 134 YELPPVSIQGSSVMFRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPG 188
Score = 60.5 bits (145), Expect = 4e-08, Method: Composition-based stats.
Identities = 22/97 (23%), Positives = 40/97 (41%), Gaps = 5/97 (5%)
Query 257 VRIEKARDIPLGATV-----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
V++ K + LG T+ R D ++IS I KG A ++G L GD++L I+ I +
Sbjct 573 VKLPKKHSVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDS 632
Query 312 KDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVI 348
+ + +L + + + I
Sbjct 633 CSMEDAVQILQQCEDLVKLKIRKDEDNSDEQESSGAI 669
Score = 57.4 bits (137), Expect = 4e-07, Method: Composition-based stats.
Identities = 19/90 (21%), Positives = 38/90 (42%), Gaps = 4/90 (4%)
Query 256 IVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
+V + K LG + + ++I +I A++ G LH GD +L I+G +
Sbjct 252 LVEVAKTPGASLGVALTTSVCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTSMEY 311
Query 312 KDVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
+ E L++ + ++P Q +
Sbjct 312 CTLAEATQFLANTTDQVKLEILPHHQTRLA 341
Score = 54.3 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 23/74 (31%), Positives = 28/74 (38%), Gaps = 1/74 (1%)
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
+IS I AE+ G+L GD V+ INGI E LL D T L +
Sbjct 501 LISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEEANQLLRDSSITSKVTLEIEFDV 560
Query 339 KPPPA-KETVIHVK 351
HVK
Sbjct 561 AESVIPSSGTFHVK 574
Score = 40.8 bits (94), Expect = 0.052, Method: Composition-based stats.
Identities = 29/150 (19%), Positives = 54/150 (36%), Gaps = 9/150 (6%)
Query 227 VAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEM--DSVIISRIV 284
V + + L + E + E + E K+ + + G +V + + V + I
Sbjct 961 VGRKSVTLRKMKQE-IKEIMSPTPVELHKVTLYKDSGMEDFGFSVADGLLEKGVYVKNIR 1019
Query 285 KGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL-----IPSQQIK 339
G + G L D +L++N + R D V L+++ L V+ + I+
Sbjct 1020 PAGPGDL-GGLKPYDRLLQVNHVRTRDFDCCLVVPLIAESGNKLDLVISRNPLASQKSIE 1078
Query 340 PPPAKETVIHVKAHFDYDPSDDPYVPCREL 369
P + F PS + RE
Sbjct 1079 QPALPSDWSEQNSAFFQQPSHGGNLETREP 1108
>sp|Q5TCQ9|MAGI3_HUMAN Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 3 OS=Homo sapiens OX=9606
GN=MAGI3 PE=1 SV=3
Length=1481
Score = 81.6 bits (200), Expect = 1e-14, Method: Composition-based stats.
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
Query 492 QNELRQRLMN-KEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGE 550
+ + +L + + +P TTR+ RD EV G DY+F+S + F+A +G +E G
Sbjct 123 KGSIDHKLQQVIRDNLYLRTIPCTTRAPRDGEVPGVDYNFISVEQFKALEESGALLESGT 182
Query 551 FEKNLYGTSIDSVR 564
++ N YGT
Sbjct 183 YDGNFYGTPKPPAE 196
Score = 67.8 bits (164), Expect = 3e-10, Method: Composition-based stats.
Identities = 30/164 (18%), Positives = 62/164 (38%), Gaps = 7/164 (4%)
Query 257 VRIEKARDIPLGATV----RNEMDSVI---ISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
V +++ + G + VI I R+++G A++ G L GD + +NG I
Sbjct 852 VVLQRKENEGFGFVILTSKNKPPPGVIPHKIGRVIEGSPADRCGKLKVGDHISAVNGQSI 911
Query 310 RGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCREL 369
+ + L+ D T+T +I ++ PP+ + P
Sbjct 912 VELSHDNIVQLIKDAGVTVTLTVIAEEEHHGPPSGTNSARQSPALQHRPMGQSQANHIPG 971
Query 370 GLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
S +G+I +S + W ++ + + + +V + Q
Sbjct 972 DRSALEGEIGKDVSTSYRHSWSDHKHLAQPDTAVISVVGSRHNQ 1015
Score = 64.7 bits (156), Expect = 2e-09, Method: Composition-based stats.
Identities = 30/168 (18%), Positives = 63/168 (38%), Gaps = 8/168 (5%)
Query 180 FPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITD 239
P + + + + Q + E+ ++T + + H +A+ + + +
Sbjct 953 SPALQH-RPMGQSQANHIPGDRSALEGEIGKDVSTSY-RHSWSDHKHLAQPDTAVISVVG 1010
Query 240 ERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD-SVIISRIVKGGAAEKSGLLHEG 298
R +++G Y E + R E + + I R+ + G A K G +H G
Sbjct 1011 SRHNQNLGCYPVELER-----GPRGFGFSLRGGKEYNMGLFILRLAEDGPAIKDGRIHVG 1065
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKET 346
D+++EING +G +L+ + +L P + P
Sbjct 1066 DQIVEINGEPTQGITHTRAIELIQAGGNKVLLLLRPGTGLIPDHGDWD 1113
Score = 54.7 bits (130), Expect = 3e-06, Method: Composition-based stats.
Identities = 24/96 (25%), Positives = 42/96 (44%), Gaps = 6/96 (6%)
Query 257 VRIEKARDIPLGA---TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
V + K ++ G S+ I I+ GAAEK G L DE++ I+GI ++GK
Sbjct 727 VFLRK-QESGFGFRVLGGDGPDQSIYIGAIIPLGAAEKDGRLRAADELMCIDGIPVKGKS 785
Query 314 VNEVFDLLSDM--HGTLTFVLIPSQQIKPPPAKETV 347
+V DL++ +G + + ++
Sbjct 786 HKQVLDLMTTAARNGHVLLTVRRKIFYGEKQPEDDS 821
Score = 45.4 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 19/112 (17%), Positives = 42/112 (38%), Gaps = 7/112 (6%)
Query 235 EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV-RNEMDSVI--ISRIVKGGAAEK 291
+ Q G V+ ++K+ + G T+ + + ++K G A +
Sbjct 390 PDMEKSHFTRDPSQLKGVLVR-ASLKKST-MGFGFTIIGGDRPDEFLQVKNVLKDGPAAQ 447
Query 292 SGLLHEGDEVLEINGIEIRGKDVNEVFDL--LSDMHGTLTFVLIPSQQIKPP 341
G + GD +++ING + G +V + L ++ + L +
Sbjct 448 DGKIAPGDVIVDINGNCVLGHTHADVVQMFQLVPVNQYVNLTLCRGYPLPDD 499
>sp|Q99KF0|CAR14_MOUSE Caspase recruitment domain-containing protein
14 OS=Mus musculus OX=10090 GN=Card14 PE=2 SV=2
Length=999
Score = 80.9 bits (198), Expect = 2e-14, Method: Composition-based stats.
Identities = 96/642 (15%), Positives = 201/642 (31%), Gaps = 127/642 (20%)
Query 51 RRSAQLERIRQQQE-DMRRRREEEGKKQELDLNSSMR-LKKLAQIPPKTGIDNPMFDTEE 108
R AQ+E ++ E D RRR E +Q +L + +R L+ A PK E
Sbjct 368 RDRAQMEISQRLVEKDALRRRVFELTEQVCELRTQLRRLQAEAPGGPK---------QEA 418
Query 109 GIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNA 168
G +++ + + L ++S+ L L +
Sbjct 419 GARELCLRGKQRLVRMHAVCPPDDSDCSLLSSTESR----LWWDLNSTSSREQM------ 468
Query 169 ITVHMNKASPPFPLISNA--QDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDK 226
++S P P + + +A++ + + E E+ T D
Sbjct 469 ---DSFRSSSPMPPSQQSLYKRVAEDFLEDPESLSFPEVLEMRLQGAT--------VDDT 517
Query 227 VAEQEMQLEPITDERVYESIGQYGGET---------------------VKIVRIEKARDI 265
+ E ++ D E Q + V ++ + +
Sbjct 518 DTDLEFEMIDGADLSQTEDSLQGSSRSLNVSESSVPVRRRPARKILSQVTVLAFQGDALL 577
Query 266 PLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIE--------IRGKDVNEV 317
+ + + I R+ G AA++ L G +++ ++ + + +
Sbjct 578 EQIGVIGGNLTGIFIHRVTPGSAADEM-ALRPGTQIMMVDYKPTKPSLRATLENTTLEQA 636
Query 318 FDLLSDMHGTLTFVLIPSQQ---------IKPPPAKETVIHVKAHFDYDPSDDPYVPCRE 368
LL ++G+ + + + +++ + D +
Sbjct 637 VGLLRRVNGSCYLSVKINTEGYKNLIQDLDAKVVTSGDSFYIRVNLAMQRGGDGELQTHC 696
Query 369 LGLSFQKGDILHVISQEDPNW--WQAYREGDEDNQP-LAGLVPGKSFQQQRE-------- 417
DILHV W A+ + G +P S QQ+
Sbjct 697 N-------DILHVTDTMFQGRSCWHAHHVNPYTMKDMEPGTIPNYSQAQQQLLALIQDMT 749
Query 418 -AMKQTIEEDKEPEKSGKLWC----------AKKNKKKRKKVLYNANKNDDYDNEEILTY 466
+ P+K ++ + ++ + + + +E T
Sbjct 750 QRCTVPRKPPGGPQKLVRIVSVDKAAVSPLTSSFDQSQWDSGKEEGGPSVCFWSESCFTL 809
Query 467 EEMSLYH-QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAG 525
+L H R RP +L P+ G+ L ++L F
Sbjct 810 APYTLVHPHRPARPRP-VLFVPRLVGR-ILGKKLC--LLQGFKQCSAE------------ 853
Query 526 RDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTL 585
++S++ + G I+ GE + + + +V ++N LL +R S++ L
Sbjct 854 ----YLSQEEYATWSQRGDIIQEGESIGDHHWITRHAVESLMNMSTHALLDVRLDSVRVL 909
Query 586 RNSDLKPYIIF--IAPPSQERLRALLAKEGKNPKP--EELRE 623
D+ P II + + ++LR L + G + + E R+
Sbjct 910 HRMDMFPIIIHVSVNEKTAKKLRKGLHRLGSSEEQFLEVARQ 951
>sp|Q8X5P4|PHNN_ECO57 Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Escherichia coli O157:H7 OX=83334 GN=phnN PE=3 SV=1
Length=185
Score = 75.5 bits (184), Expect = 2e-14, Method: Composition-based stats.
Identities = 34/188 (18%), Positives = 60/188 (32%), Gaps = 18/188 (10%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+ I L+GP G++ L L +E+ + A + TR + +S Q F
Sbjct 3 GKLIWLMGPSGSGKDSLLAELRLREQTQLLVAHRYITRDASAGSEN---HIALSEQEFFT 59
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK----TLRNSDLKPYI 594
YG ++ + +++G L + R +
Sbjct 60 RAGQNLLALSWHANGLYYGVGVE-IDLWLHAGFDVL----VNGSRAHLPQARARYQSALL 114
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNS-DLDKAYQ 653
S E LR L G+ E + R Q+ + N L ++
Sbjct 115 PICLQVSPEILRQRLENRGRENASEINARLARAARYTPQDC-----HTLNNDGSLRQSVD 169
Query 654 ELLRLINK 661
LL LI++
Sbjct 170 TLLTLIHQ 177
>sp|Q5F488|MAGI3_CHICK Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 3 OS=Gallus gallus OX=9031
GN=MAGI3 PE=2 SV=1
Length=1128
Score = 80.9 bits (198), Expect = 2e-14, Method: Composition-based stats.
Identities = 22/74 (30%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query 492 QNELRQRLMN-KEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGE 550
+ + +L + + +P TTR+ RD EV G DY+F+ + F+A +G +E G
Sbjct 125 KGSIDHKLQQVIRDNLYLRTIPCTTRAPRDGEVPGVDYNFIPVEQFKALEESGALLESGT 184
Query 551 FEKNLYGTSIDSVR 564
++ N YGT
Sbjct 185 YDGNFYGTPKPPAE 198
Score = 71.6 bits (174), Expect = 2e-11, Method: Composition-based stats.
Identities = 45/242 (19%), Positives = 80/242 (33%), Gaps = 34/242 (14%)
Query 190 AQEVQTV----LKPVHHKEGQELTALLNTPHIQALLLAHDKV-----------AEQEMQL 234
A E+ + +K HK+ +L + Q LL K+ Q +
Sbjct 772 ADELMCIDGVPVKGKSHKQVLDLMTS-AARNGQVLLTVRRKIFFGGEKQAEEDESQAVVT 830
Query 235 EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV----RNEMDSVI---ISRIVKGG 287
+ + V V +++ + G + VI I R++ G
Sbjct 831 QNSSPRLNRAEFATQQSPEVYDVCLQRKENEGFGFVILTSKNKPPPGVIPHKIGRVIDGS 890
Query 288 AAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV 347
A++ G L GD + +NG I + + L+ D +T ++ ++ + PP+
Sbjct 891 PADQCGKLKVGDRISAVNGQSIVELSHDSIVQLIKDAGHVVTLTVVAEEEHRGPPSGTNS 950
Query 348 IHVKAHFDYDPSDDPYVPCRELGLSFQK----GDILHVISQEDPNWWQAYREGDEDNQPL 403
A P P P + S + G+ +S W E QP
Sbjct 951 ----AKQSPAPQHRPLGPAQSSASSTDRGATEGEAGKEVSNSYRLSW---PEHKHLAQPD 1003
Query 404 AG 405
AG
Sbjct 1004 AG 1005
Score = 60.8 bits (146), Expect = 3e-08, Method: Composition-based stats.
Identities = 22/88 (25%), Positives = 40/88 (45%), Gaps = 4/88 (5%)
Query 257 VRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
V +E+ G ++R + + I R+ + G A K G +H GD+++EING +G
Sbjct 1025 VELERG-PRGFGFSLRGGKEYNMGLFILRLAEDGPAVKDGRVHVGDQIVEINGEPTQGIT 1083
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
+L+ + +L P + P
Sbjct 1084 HTRAIELIQAGGNKVLLLLRPGTGLIPD 1111
Score = 55.4 bits (132), Expect = 1e-06, Method: Composition-based stats.
Identities = 25/116 (22%), Positives = 49/116 (42%), Gaps = 8/116 (7%)
Query 227 VAEQEMQLEPITDERVYESIGQYGGETVKI--VRIEKARDIPLG---ATVRNEMDSVIIS 281
V +L+P +++ + + V + K ++ G + I
Sbjct 697 VRSGSPKLDPSEVYLKSKTMYEDKPPNTRDLDVFLRK-QESGFGFRVLGGDGADQPIYIG 755
Query 282 RIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM--HGTLTFVLIPS 335
I+ GAAEK G L DE++ I+G+ ++GK +V DL++ +G + +
Sbjct 756 AIIPLGAAEKDGRLRAADELMCIDGVPVKGKSHKQVLDLMTSAARNGQVLLTVRRK 811
Score = 46.2 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 26/122 (21%), Positives = 44/122 (36%), Gaps = 15/122 (12%)
Query 261 KARDIPLGATV-RNEMDSVI--ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
K + G T+ + + ++K G A + G + GD +++ING + G +V
Sbjct 416 KKSTMGFGFTIIGGDRPDEFLQVKNVLKDGPAAQDGRIAPGDVIVDINGNCVLGHTHADV 475
Query 318 FDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCREL-GLSFQKG 376
+ F L+P Q + + DP D + G KG
Sbjct 476 VQM---------FQLVPVNQYVNMTLCRG--YPLPDDNEDPVVDIVTATPIINGPPVTKG 524
Query 377 DI 378
DI
Sbjct 525 DI 526
Score = 39.7 bits (91), Expect = 0.12, Method: Composition-based stats.
Identities = 33/180 (18%), Positives = 57/180 (32%), Gaps = 27/180 (15%)
Query 287 GAAEKSGLL-HEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKE 345
G A SG GD +LE+NG + G + ++ + +
Sbjct 58 GPALLSGKAPAPGDVLLEVNGTPVSGLTHRDTLAVIRHFREPVRLK----------TVRP 107
Query 346 TVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAG 405
+ K Y L L FQKG I H + Q + P G
Sbjct 108 GKVINKDLRHY------------LSLQFQKGSIDHKLQQVIRDNLYLRTIPCTTRAPRDG 155
Query 406 LVPGKSF----QQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNE 461
VPG + +Q +A++++ + G + K + + +DN+
Sbjct 156 EVPGVDYNFIPVEQFKALEESGALLESGTYDGNFYGTPKPPAEPSPFQPDPVDQVLFDND 215
>sp|P16690|PHNN_ECOLI Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Escherichia coli (strain K12) OX=83333 GN=phnN PE=1 SV=1
Length=185
Score = 75.1 bits (183), Expect = 3e-14, Method: Composition-based stats.
Identities = 34/188 (18%), Positives = 60/188 (32%), Gaps = 18/188 (10%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+ I L+GP G++ L L +E+ + A + TR + +S Q F
Sbjct 3 GKLIWLMGPSGSGKDSLLAELRLREQTQLLVAHRYITRDASAGSEN---HIALSEQEFFT 59
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK----TLRNSDLKPYI 594
YG ++ + +++G L + R +
Sbjct 60 RAGQNLLALSWHANGLYYGVGVE-IDLWLHAGFDVL----VNGSRAHLPQARARYQSALL 114
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNS-DLDKAYQ 653
S E LR L G+ E + R Q+ + N L ++
Sbjct 115 PVCLQVSPEILRQRLENRGRENASEINARLARAARYTPQDC-----HTLNNDGSLRQSVD 169
Query 654 ELLRLINK 661
LL LI++
Sbjct 170 TLLTLIHQ 177
>sp|Q925T6|GRIP1_MOUSE Glutamate receptor-interacting protein
1 OS=Mus musculus OX=10090 GN=Grip1 PE=1 SV=1
Length=1127
Score = 80.1 bits (196), Expect = 4e-14, Method: Composition-based stats.
Identities = 32/114 (28%), Positives = 53/114 (46%), Gaps = 5/114 (4%)
Query 261 KARDIPLGATVRN---EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
K PLG T+ D +IIS + KGG AE++G +H GD +L IN ++GK ++E
Sbjct 676 KRYGGPLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEA 735
Query 318 FDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHF-DYDPSDDPYVPCRELG 370
LL T+T + + + + + H D ++ P ++ G
Sbjct 736 IHLLQMAGETVTLKIKKQTDAQSASSPK-KFPIPGHSGDLGDGEEDPSPIQKPG 788
Score = 65.8 bits (159), Expect = 1e-09, Method: Composition-based stats.
Identities = 24/112 (21%), Positives = 45/112 (40%), Gaps = 10/112 (9%)
Query 226 KVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV-----RNEMDSVII 280
V E E +L P++ TV++ ++ RN+ V+I
Sbjct 128 VVLEVEYELPPVS-----VQGSSVMFRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRPVVI 182
Query 281 SRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ + GG A++ G + GD +L ++GI + G E +L T ++
Sbjct 183 TCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLI 234
Score = 62.0 bits (149), Expect = 2e-08, Method: Composition-based stats.
Identities = 31/175 (18%), Positives = 58/175 (33%), Gaps = 27/175 (15%)
Query 221 LLAHDKVAEQEMQLEPITDERVYESIGQYGGE--TVKIVRIEKARDIPLGATVRNEMDS- 277
L + + D + E +V + K LG TV +D
Sbjct 16 LTKDESPYTKSASQTKPPDGALAVRRQSIPEEFKGSTVVELMKKEGTTLGLTVSGGIDKD 75
Query 278 --VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+S + +GG A +S L GD + +NGI + +E+ LL ++ + +
Sbjct 76 GKPRVSNLRQGGIAARSDQLDVGDYIKAVNGINLAKFRHDEIISLLKNVGERVVLEV--E 133
Query 336 QQIKPPPAKETVIHVK--------------------AHFDYDPSDDPYVPCRELG 370
++ P + + + + AH D + S + C G
Sbjct 134 YELPPVSVQGSSVMFRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPG 188
Score = 62.0 bits (149), Expect = 2e-08, Method: Composition-based stats.
Identities = 22/97 (23%), Positives = 40/97 (41%), Gaps = 5/97 (5%)
Query 257 VRIEKARDIPLGATV-----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
V++ K + LG T+ R D ++IS I KG A ++G L GD++L I+ I +
Sbjct 573 VKLPKKHSVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDN 632
Query 312 KDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVI 348
+ + +L + + + I
Sbjct 633 CSMEDAVQILQQCEDLVKLKIRKDEDNSDEQESSGAI 669
Score = 57.4 bits (137), Expect = 4e-07, Method: Composition-based stats.
Identities = 19/90 (21%), Positives = 38/90 (42%), Gaps = 4/90 (4%)
Query 256 IVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
+V + K LG + + ++I +I A++ G LH GD +L I+G +
Sbjct 252 LVEVAKTPGASLGVALTTSVCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTSMEY 311
Query 312 KDVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
+ E L++ + ++P Q +
Sbjct 312 CTLAEATQFLANTTDQVKLEILPHHQTRLA 341
Score = 54.3 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 23/74 (31%), Positives = 28/74 (38%), Gaps = 1/74 (1%)
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
+IS I AE+ G+L GD V+ INGI E LL D T L +
Sbjct 501 LISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEEANQLLRDSSITSKVTLEIEFDV 560
Query 339 KPPPA-KETVIHVK 351
HVK
Sbjct 561 AESVIPSSGTFHVK 574
Score = 40.0 bits (92), Expect = 0.094, Method: Composition-based stats.
Identities = 29/150 (19%), Positives = 54/150 (36%), Gaps = 9/150 (6%)
Query 227 VAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEM--DSVIISRIV 284
V + + L + E + E + E K+ + + G +V + + V + I
Sbjct 976 VGRKSVTLRKMKQE-IKEIMSPTPVELHKVTLYKDSGMEDFGFSVADGLLEKGVYVKNIR 1034
Query 285 KGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL-----IPSQQIK 339
G + G L D +L++N + R D V L+++ L V+ + I+
Sbjct 1035 PAGPGD-VGGLKPYDRLLQVNHVRTRDFDCCLVVPLIAESGNKLDLVISRNPLASQKSIE 1093
Query 340 PPPAKETVIHVKAHFDYDPSDDPYVPCREL 369
P + F PS + RE
Sbjct 1094 QPALPSDWSEQNSAFFQQPSHGGNLETREP 1123
>sp|Q329H3|PHNN_SHIDS Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Shigella dysenteriae serotype 1 (strain Sd197) OX=300267
GN=phnN PE=3 SV=1
Length=185
Score = 74.3 bits (181), Expect = 4e-14, Method: Composition-based stats.
Identities = 34/188 (18%), Positives = 61/188 (32%), Gaps = 18/188 (10%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+ I L+GP G++ L L +E+ + A + TR + +S Q F
Sbjct 3 GKLIWLMGPSGSGKDSLLAELRLREQTQLLVAHRYITRDASAGSEN---HIALSEQEFFT 59
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK----TLRNSDLKPYI 594
YG ++ + +++G L + R +
Sbjct 60 RAGQNLLALSWHANGLYYGVGVE-IDLWLHAGFDVL----VNGSRAHLPQARARYQSALL 114
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNS-DLDKAYQ 653
S E LR L G+ E ++ R Q+ + N L ++
Sbjct 115 PICLQVSPEILRQRLENRGRENASEINARLVRAARYTPQDC-----HTLNNDGSLCQSVD 169
Query 654 ELLRLINK 661
LL LI++
Sbjct 170 TLLTLIHQ 177
>sp|A9CKM5|PHNN_AGRFC Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Agrobacterium fabrum (strain C58 / ATCC 33970) OX=176299
GN=phnN PE=3 SV=1
Length=183
Score = 73.9 bits (180), Expect = 6e-14, Method: Composition-based stats.
Identities = 35/190 (18%), Positives = 68/190 (36%), Gaps = 16/190 (8%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRS--RRDQEVAGRDYHFVSRQAFEA 538
I+++GP G++ L + R H TR R + G ++ VS F
Sbjct 1 MIVIVGPSGAGKDTLMDYAAAQLSGRPGF---HFTRRVITRSCDAGGENHDAVSMHEFNQ 57
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
AG F + YG +V + + +G + + + +L + + ++ I
Sbjct 58 LEDAGAFAVSWQAHGLKYGIP-AAVYRHLEAGDVVIANGSRSALPHFGTAFSRLKVVNIV 116
Query 599 P-PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQEL-L 656
P + L L + G+ + + LR + + FD V D A ++
Sbjct 117 ARP--DVLARRLEQRGRESRDDILRRLERSS----LAVAGDFDVTTV--DNSGAIEDAGK 168
Query 657 RLINKLDTEP 666
++ L
Sbjct 169 TIMQVLQQSA 178
>sp|B1LPR3|PHNN_ECOSM Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Escherichia coli (strain SMS-3-5 / SECEC) OX=439855 GN=phnN
PE=3 SV=1
Length=185
Score = 73.6 bits (179), Expect = 1e-13, Method: Composition-based stats.
Identities = 34/189 (18%), Positives = 63/189 (33%), Gaps = 20/189 (11%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+ I L+G G++ L L +E+ + A + TR+ + +S Q F
Sbjct 3 GKLIWLMGASGSGKDSLLTELRQREQTQLLVAHRYITRAASAGSEN---HIALSEQEFFT 59
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK----TLRNSDLKPYI 594
YG ++ + +++G + + R +
Sbjct 60 RAGQNLLALSWHANGLYYGVGVE-IDLWLHAG----FDVVVNGSRAHLPQARARYQSALL 114
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD--LDKAY 652
S E LR L G+ E + R Q D +N+D L ++
Sbjct 115 PVCLQVSPEILRQRLENRGRENASEINARLARAARYTPQ------DCLTLNNDGSLRQSV 168
Query 653 QELLRLINK 661
+LL LI++
Sbjct 169 DKLLTLIHQ 177
>sp|Q6D9W6|PHNN_PECAS Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)
OX=218491 GN=phnN PE=3 SV=1
Length=188
Score = 73.2 bits (178), Expect = 1e-13, Method: Composition-based stats.
Identities = 32/187 (17%), Positives = 64/187 (34%), Gaps = 19/187 (10%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
+ I LIGP G++ L + + R A + TR E+ G ++ ++ + F
Sbjct 3 KLIYLIGPSGAGKDSLLRAIRQLPLPRLLVAHRYITR---PAEIQGENHIALTPEEFAIR 59
Query 540 IAAGKF-IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK----TLRNSDLKPYI 594
G F ++ + + YG I+ + + G + + R
Sbjct 60 QQLGIFALDW-QAHQCHYGIGIE-IDYWLQRGSYVI----VNGSRAYLTQARERYGNTLF 113
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNS--DLDKAY 652
S+ LR L G+ + + + E + D ++N+ DL +
Sbjct 114 PICLTVSESALRQRLRARGRESEQQIATRLQRAEDEQSRLQS---DCILLNNDGDLQRTL 170
Query 653 QELLRLI 659
L+
Sbjct 171 STFQSLL 177
>sp|C1DLT0|PHNN_AZOVD Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Azotobacter vinelandii (strain DJ / ATCC BAA-1303) OX=322710
GN=phnN PE=3 SV=1
Length=183
Score = 73.2 bits (178), Expect = 1e-13, Method: Composition-based stats.
Identities = 34/156 (22%), Positives = 54/156 (35%), Gaps = 14/156 (9%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVP-HTTRSRRDQEVAGRDYHFVSRQAFE 537
R I L+G G++ L + + + V TRS E G D VS + FE
Sbjct 3 GRLIYLMGASGSGKDSLLEAVRERVLAAGGRIVRRVVTRSP---EAVGEDALGVSPERFE 59
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQ----SLKTLRNSDLKPY 593
+A G F H YG + + G+ L + + R +L
Sbjct 60 QLLAEGAFALHWRANGLAYGIPRQ-IDDWLVDGRDVL--INGSRGHLAAARRRYPELCAV 116
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTR 629
++ + P + LR L G+ E + R
Sbjct 117 LLTVEP---QVLRQRLLARGRETIEEIEARLARNAR 149
>sp|Q9WVQ1|MAGI2_MOUSE Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 2 OS=Mus musculus OX=10090
GN=Magi2 PE=1 SV=2
Length=1275
Score = 77.8 bits (190), Expect = 2e-13, Method: Composition-based stats.
Identities = 31/121 (26%), Positives = 45/121 (37%), Gaps = 26/121 (21%)
Query 492 QNELRQRLMNKEKDR-FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGE 550
+ + L +D + VP TTR ++ EV G DY F++ + F +G +E G
Sbjct 118 KGSVDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEEFMELEKSGALLESGT 177
Query 551 FEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP---PSQERLRA 607
+E N YGT LL++ Q I P PS E R
Sbjct 178 YEDNYYGTPKPPAEPA------PLLNVTDQ----------------ILPGATPSAEGKRK 215
Query 608 L 608
Sbjct 216 R 216
Score = 68.2 bits (165), Expect = 2e-10, Method: Composition-based stats.
Identities = 27/122 (22%), Positives = 51/122 (42%), Gaps = 11/122 (9%)
Query 236 PITDERVYESIGQYGGETVKIVRIEKARDIPLGATV-----RNEMDSVI-----ISRIVK 285
P ++ E + +T +V K + G + R E + I I RI+
Sbjct 900 PSSNASPPEGFASHSLQTSDVVIHRK-ENEGFGFVIISSLNRPESGATITVPHKIGRIID 958
Query 286 GGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKE 345
G A++ L GD +L +NG I ++ L+ D ++T +IP +++ P +
Sbjct 959 GSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAP 1018
Query 346 TV 347
+
Sbjct 1019 SS 1020
Score = 62.8 bits (151), Expect = 1e-08, Method: Composition-based stats.
Identities = 31/134 (23%), Positives = 54/134 (40%), Gaps = 3/134 (2%)
Query 214 TPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRN 273
P L + E Q+ P T R+ S Y V + R+E +
Sbjct 738 KPDPYELYEKSRAIYESRQQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRI-LGGDE 796
Query 274 EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL--SDMHGTLTFV 331
++I ++ G+A++ G LH GDE++ ++GI + GK V DL+ + +G +
Sbjct 797 PGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLT 856
Query 332 LIPSQQIKPPPAKE 345
+ P E
Sbjct 857 VRRKVLCGGEPCPE 870
Score = 55.1 bits (131), Expect = 2e-06, Method: Composition-based stats.
Identities = 22/115 (19%), Positives = 43/115 (37%), Gaps = 12/115 (10%)
Query 233 QLEPITDERVYESIGQYGGETVK--------IVRIEKARDIPLGATVRNEMD---SVIIS 281
Q P+ + QY + V +EK G ++R + + +
Sbjct 1108 QPPPLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGA-KGFGFSIRGGREYKMDLYVL 1166
Query 282 RIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQ 336
R+ + G A ++G + GD+++EING R +L+ + +L
Sbjct 1167 RLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKSGGRRVRLLLKRGT 1221
Score = 51.6 bits (122), Expect = 2e-05, Method: Composition-based stats.
Identities = 32/163 (20%), Positives = 56/163 (34%), Gaps = 13/163 (8%)
Query 215 PHIQALLLAHDKVAEQEMQ---LEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV 271
PH H A+ ++ P+ D+ V + + + I K G T+
Sbjct 565 PH-----SLHSMPADGQLDGTYPPPVHDDNVSMASSGATQAELMTLTIVKGAQ-GFGFTI 618
Query 272 RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMH-GTLTF 330
+ + +I+ + L EGD ++EIN ++ EV D+L D G+ T
Sbjct 619 ADSPTGQRVKQILD---IQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPVGSETS 675
Query 331 VLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSF 373
++I P + + P P L F
Sbjct 676 LIIHRGGFFSPWKTPKPMMDRWENQGSPQTSLSAPAVPQNLPF 718
Score = 44.3 bits (103), Expect = 0.004, Method: Composition-based stats.
Identities = 16/87 (18%), Positives = 34/87 (39%), Gaps = 5/87 (6%)
Query 261 KARDIPLGATV-RNEMDSVI--ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
K ++ G T+ + + ++ G A + G + GD ++ IN + + G +V
Sbjct 429 KKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADV 488
Query 318 FDLLS--DMHGTLTFVLIPSQQIKPPP 342
L + ++ VL + P
Sbjct 489 VKLFQSVPIGQSVNLVLCRGYPLPFDP 515
>sp|Q9MZL7|CACB1_BOVIN Voltage-dependent L-type calcium channel
subunit beta-1 OS=Bos taurus OX=9913 GN=CACNB1 PE=1 SV=1
Length=598
Score = 77.4 bits (189), Expect = 2e-13, Method: Composition-based stats.
Identities = 65/388 (17%), Positives = 124/388 (32%), Gaps = 57/388 (15%)
Query 310 RGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCREL 369
+ E + L + + KP V+ + Y+PS VP + +
Sbjct 70 SDVSLEEDREALRKEAERQALAQLEKAKTKPVA-----FAVRTNVGYNPSPGDEVPVQGV 124
Query 370 GLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK-------SFQQQREAMKQT 422
++F+ D LH+ + + +WW G +P Q+Q+ +
Sbjct 125 AITFEPKDFLHIKEKYNNDWWIGRLV---KEGCEVGFIPSPVKLDSLRLLQEQKLRQNRL 181
Query 423 IEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPI 482
S L R+ + K E + Y+ + RPI
Sbjct 182 SSSKSGDNSSSSLGDVVTGT--RRPTPPASAKQKQKSTEHVPPYDVVPSM-------RPI 232
Query 483 ILIGPQNCG---QNELRQRLMNKEKDRFASAVPHTTR------SRRDQEVAGRDYHFVSR 533
IL+GP G + +++ L + K RF + T ++R + + R
Sbjct 233 ILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIER 292
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKI---CLLSLR-TQSLKTLRNSD 589
+ + E + + ++ + L L +
Sbjct 293 SNTRSSL--------AEVQ--------SEIERIFELARTLQLVALDADTINHPAQLSKTS 336
Query 590 LKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLD 649
L P I++I S + L+ L+ GK + + L I + ++ Q FD + + L+
Sbjct 337 LAPIIVYIKITSPKVLQRLIKSRGK-SQSKHLNVQIAASEKLAQCPPEMFDIILDENQLE 395
Query 650 KAYQELLRLIN---KLDTEPQWVPSTWL 674
A + L + K P P L
Sbjct 396 DACEHLAEYLEAYWKATHPPSSTPPNPL 423
>sp|O88382|MAGI2_RAT Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 2 OS=Rattus norvegicus OX=10116
GN=Magi2 PE=1 SV=1
Length=1277
Score = 77.8 bits (190), Expect = 2e-13, Method: Composition-based stats.
Identities = 31/121 (26%), Positives = 45/121 (37%), Gaps = 25/121 (21%)
Query 492 QNELRQRLMNKEKDR-FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGE 550
+ + L +D + VP TTR ++ EV G DY F++ + F +G +E G
Sbjct 118 KGSVDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGT 177
Query 551 FEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP---PSQERLRA 607
+E N YGT LL++ Q I P PS E R
Sbjct 178 YEDNYYGTPKPPAEPA-----PLLLNVTDQ----------------ILPGATPSAEGKRK 216
Query 608 L 608
Sbjct 217 R 217
Score = 67.0 bits (162), Expect = 4e-10, Method: Composition-based stats.
Identities = 18/68 (26%), Positives = 34/68 (50%), Gaps = 0/68 (0%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
I RI+ G A++ L GD +L +NG I ++ L+ D ++T +IP +++
Sbjct 954 IGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELN 1013
Query 340 PPPAKETV 347
P + +
Sbjct 1014 NPTSAPSS 1021
Score = 62.8 bits (151), Expect = 9e-09, Method: Composition-based stats.
Identities = 31/134 (23%), Positives = 54/134 (40%), Gaps = 3/134 (2%)
Query 214 TPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRN 273
P L + E Q+ P T R+ S Y V + R+E +
Sbjct 739 KPDPYELYEKSRAIYESRQQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRI-LGGDE 797
Query 274 EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL--SDMHGTLTFV 331
++I ++ G+A++ G LH GDE++ ++GI + GK V DL+ + +G +
Sbjct 798 PGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLT 857
Query 332 LIPSQQIKPPPAKE 345
+ P E
Sbjct 858 VRRKVLCGGEPCPE 871
Score = 55.4 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 33/194 (17%), Positives = 63/194 (32%), Gaps = 24/194 (12%)
Query 166 HNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHH--------KEGQELTALLNTPHI 217
H+ + + + P P N+ L+ H K Q++ + P
Sbjct 1031 HSPLAQQHSPLAQPSPATPNSPVAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPF 1090
Query 218 ----QALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVK--------IVRIEKARDI 265
Q L Q P+ + QY + V +EK
Sbjct 1091 TDYRQPPLDYRQPPGGDYSQPSPLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGA-K 1149
Query 266 PLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
G ++R + + + R+ + G A ++G + GD+++EING R +L+
Sbjct 1150 GFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIK 1209
Query 323 DMHGTLTFVLIPSQ 336
+ +L
Sbjct 1210 SGGRRVRLLLKRGT 1223
Score = 51.6 bits (122), Expect = 2e-05, Method: Composition-based stats.
Identities = 32/163 (20%), Positives = 56/163 (34%), Gaps = 13/163 (8%)
Query 215 PHIQALLLAHDKVAEQEMQ---LEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV 271
PH H A+ ++ P+ D+ V + + + I K G T+
Sbjct 566 PH-----SLHSMPADGQLDGTYPPPVHDDNVSVASSGATQAELMTLTIVKGA-KGFGFTI 619
Query 272 RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMH-GTLTF 330
+ + +I+ + L EGD ++EIN ++ EV D+L D G+ T
Sbjct 620 ADSPTGQRVKQILD---IQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPVGSETS 676
Query 331 VLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSF 373
++I P + + P P L F
Sbjct 677 LIIHRGGFFSPWKTPKPMVDRWENQGSPQTSLSAPAVPQSLPF 719
Score = 44.7 bits (104), Expect = 0.004, Method: Composition-based stats.
Identities = 16/87 (18%), Positives = 34/87 (39%), Gaps = 5/87 (6%)
Query 261 KARDIPLGATV-RNEMDSVI--ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
K ++ G T+ + + ++ G A + G + GD ++ IN + + G +V
Sbjct 430 KKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADV 489
Query 318 FDLLS--DMHGTLTFVLIPSQQIKPPP 342
L + ++ VL + P
Sbjct 490 VKLFQSVPIGQSVNLVLCRGYPLPFDP 516
>sp|Q02641|CACB1_HUMAN Voltage-dependent L-type calcium channel
subunit beta-1 OS=Homo sapiens OX=9606 GN=CACNB1 PE=1 SV=3
Length=598
Score = 77.0 bits (188), Expect = 2e-13, Method: Composition-based stats.
Identities = 65/388 (17%), Positives = 124/388 (32%), Gaps = 57/388 (15%)
Query 310 RGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCREL 369
+ E + L + + KP V+ + Y+PS VP + +
Sbjct 70 SDVSLEEDREALRKEAERQALAQLEKAKTKPVA-----FAVRTNVGYNPSPGDEVPVQGV 124
Query 370 GLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK-------SFQQQREAMKQT 422
++F+ D LH+ + + +WW G +P Q+Q+ +
Sbjct 125 AITFEPKDFLHIKEKYNNDWWIGRLV---KEGCEVGFIPSPVKLDSLRLLQEQKLRQNRL 181
Query 423 IEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPI 482
S L R+ + K E + Y+ + RPI
Sbjct 182 GSSKSGDNSSSSLGDVVTGT--RRPTPPASAKQKQKSTEHVPPYDVVPSM-------RPI 232
Query 483 ILIGPQNCG---QNELRQRLMNKEKDRFASAVPHTTR------SRRDQEVAGRDYHFVSR 533
IL+GP G + +++ L + K RF + T ++R + + R
Sbjct 233 ILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIER 292
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKI---CLLSLR-TQSLKTLRNSD 589
+ + E + + ++ + L L +
Sbjct 293 SNTRSSL--------AEVQ--------SEIERIFELARTLQLVALDADTINHPAQLSKTS 336
Query 590 LKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLD 649
L P I++I S + L+ L+ GK + + L I + ++ Q FD + + L+
Sbjct 337 LAPIIVYIKITSPKVLQRLIKSRGK-SQSKHLNVQIAASEKLAQCPPEMFDIILDENQLE 395
Query 650 KAYQELLRLIN---KLDTEPQWVPSTWL 674
A + L + K P P L
Sbjct 396 DACEHLAEYLEAYWKATHPPSSTPPNPL 423
>sp|Q60631|GRB2_MOUSE Growth factor receptor-bound protein 2 OS=Mus
musculus OX=10090 GN=Grb2 PE=1 SV=1
Length=217
Score = 73.2 bits (178), Expect = 2e-13, Method: Composition-based stats.
Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 7/63 (11%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+V+A FD+DP +D L F++GD +HV+ DPNWW+ G P + P
Sbjct 160 YVQALFDFDPQEDGE-------LGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTP 212
Query 409 GKS 411
Sbjct 213 VNR 215
Score = 42.4 bits (98), Expect = 0.006, Method: Composition-based stats.
Identities = 22/108 (20%), Positives = 43/108 (40%), Gaps = 30/108 (28%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE-DPNWWQAYREGDEDNQPLAGLVPGK 410
A +D+ + D LSF++GDIL V+++E D NW++A G + G +P
Sbjct 5 AKYDFKATADDE-------LSFKRGDILKVLNEECDQNWYKAELNGKD------GFIPKN 51
Query 411 SFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDY 458
+ + + K + K +++L + +
Sbjct 52 YIEMKPHPW----------------FFGKIPRAKAEEMLSKQRHDGAF 83
>sp|P62994|GRB2_RAT Growth factor receptor-bound protein 2 OS=Rattus
norvegicus OX=10116 GN=Grb2 PE=1 SV=1
Length=217
Score = 73.2 bits (178), Expect = 2e-13, Method: Composition-based stats.
Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 7/63 (11%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+V+A FD+DP +D L F++GD +HV+ DPNWW+ G P + P
Sbjct 160 YVQALFDFDPQEDGE-------LGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTP 212
Query 409 GKS 411
Sbjct 213 VNR 215
Score = 42.4 bits (98), Expect = 0.006, Method: Composition-based stats.
Identities = 22/108 (20%), Positives = 43/108 (40%), Gaps = 30/108 (28%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE-DPNWWQAYREGDEDNQPLAGLVPGK 410
A +D+ + D LSF++GDIL V+++E D NW++A G + G +P
Sbjct 5 AKYDFKATADDE-------LSFKRGDILKVLNEECDQNWYKAELNGKD------GFIPKN 51
Query 411 SFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDY 458
+ + + K + K +++L + +
Sbjct 52 YIEMKPHPW----------------FFGKIPRAKAEEMLSKQRHDGAF 83
>sp|Q5R4J7|GRB2_PONAB Growth factor receptor-bound protein 2 OS=Pongo
abelii OX=9601 GN=GRB2 PE=2 SV=1
Length=217
Score = 73.2 bits (178), Expect = 2e-13, Method: Composition-based stats.
Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 7/63 (11%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+V+A FD+DP +D L F++GD +HV+ DPNWW+ G P + P
Sbjct 160 YVQALFDFDPQEDGE-------LGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTP 212
Query 409 GKS 411
Sbjct 213 VNR 215
Score = 42.4 bits (98), Expect = 0.006, Method: Composition-based stats.
Identities = 22/108 (20%), Positives = 43/108 (40%), Gaps = 30/108 (28%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE-DPNWWQAYREGDEDNQPLAGLVPGK 410
A +D+ + D LSF++GDIL V+++E D NW++A G + G +P
Sbjct 5 AKYDFKATADDE-------LSFKRGDILKVLNEECDQNWYKAELNGKD------GFIPKN 51
Query 411 SFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDY 458
+ + + K + K +++L + +
Sbjct 52 YIEMKPHPW----------------FFGKIPRAKAEEMLSKQRHDGAF 83
>sp|P62993|GRB2_HUMAN Growth factor receptor-bound protein 2 OS=Homo
sapiens OX=9606 GN=GRB2 PE=1 SV=1
Length=217
Score = 73.2 bits (178), Expect = 2e-13, Method: Composition-based stats.
Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 7/63 (11%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+V+A FD+DP +D L F++GD +HV+ DPNWW+ G P + P
Sbjct 160 YVQALFDFDPQEDGE-------LGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTP 212
Query 409 GKS 411
Sbjct 213 VNR 215
Score = 42.4 bits (98), Expect = 0.006, Method: Composition-based stats.
Identities = 22/108 (20%), Positives = 43/108 (40%), Gaps = 30/108 (28%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE-DPNWWQAYREGDEDNQPLAGLVPGK 410
A +D+ + D LSF++GDIL V+++E D NW++A G + G +P
Sbjct 5 AKYDFKATADDE-------LSFKRGDILKVLNEECDQNWYKAELNGKD------GFIPKN 51
Query 411 SFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDY 458
+ + + K + K +++L + +
Sbjct 52 YIEMKPHPW----------------FFGKIPRAKAEEMLSKQRHDGAF 83
>sp|Q4L1J4|MAGI1_RAT Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 1 OS=Rattus norvegicus OX=10116
GN=Magi1 PE=1 SV=1
Length=1255
Score = 77.4 bits (189), Expect = 3e-13, Method: Composition-based stats.
Identities = 32/97 (33%), Positives = 49/97 (51%), Gaps = 7/97 (7%)
Query 492 QNELRQRLMNKEKDR-FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGE 550
+ L +D + AVP TTRS R+ EV G DY F++ + F +G +E G
Sbjct 122 KGSPDHELQQTIRDNLYRHAVPCTTRSPREGEVPGVDYSFLTVKEFLDLEQSGTLLEVGT 181
Query 551 FEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRN 587
+E N YGT + V SGK+ + T +L +L++
Sbjct 182 YEGNYYGTPKPPSQPV--SGKV----ITTDALHSLQS 212
Score = 73.6 bits (179), Expect = 4e-12, Method: Composition-based stats.
Identities = 19/63 (30%), Positives = 34/63 (54%), Gaps = 0/63 (0%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
I RI++G A++ G L GD +L +NG I K +++ +L+ + T+T +IP +
Sbjct 1037 IGRIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKEAGNTVTLRIIPGDESS 1096
Query 340 PPP 342
Sbjct 1097 NAT 1099
Score = 57.0 bits (136), Expect = 5e-07, Method: Composition-based stats.
Identities = 24/118 (20%), Positives = 44/118 (37%), Gaps = 6/118 (5%)
Query 229 EQEMQLEPITDERVYESIGQYGGE-----TVKIVRIEKARDIPLGATVRNEMDSVIISRI 283
++ + +E G + TV++ R K L R + + R+
Sbjct 1122 QETRTTTKPKPDSQFEFKGPQATQEQDFYTVELERGAKGFGFSLRG-GREYNMDLYVLRL 1180
Query 284 VKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
+ G AE+ G + GDE+LEING + + +L+ + + L P
Sbjct 1181 AEDGPAERCGKMRIGDEILEINGETTKNMKHSRAIELIKNGGRRVRLFLRRGDGSVPE 1238
Score = 55.8 bits (133), Expect = 1e-06, Method: Composition-based stats.
Identities = 20/79 (25%), Positives = 31/79 (39%), Gaps = 3/79 (4%)
Query 260 EKARDIPLGATVRNE-MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVF 318
K NE + + I IV GAA+ G L GDE++ ++G + GK V
Sbjct 845 RKETGFGFRILGGNEPGEPIYIGHIVPLGAADTDGRLRSGDELICVDGTPVIGKSHQLVV 904
Query 319 DLLSDM--HGTLTFVLIPS 335
L+ G + +
Sbjct 905 QLMQQAAKQGHVNLTVRRK 923
Score = 42.7 bits (99), Expect = 0.012, Method: Composition-based stats.
Identities = 24/149 (16%), Positives = 45/149 (30%), Gaps = 16/149 (11%)
Query 226 KVAEQEMQLEPITDERVYE-----------SIGQYGGETVKIVRIEKARDIPLGATVRNE 274
V P E E + + G+ + + +R +E
Sbjct 431 VVPPVAPSHPPSNPEPAREAPLQGKPFFTRNPSELEGKFIHTKLRKSSRGFGFTVVGGDE 490
Query 275 MDSVI-ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS--DMHGTLTFV 331
D + I +V G A G + GD ++ +N + G +V + + ++
Sbjct 491 PDEFLQIKSLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVVKIFQSIPIGASVDLE 550
Query 332 LIPSQQIKPPPAKETVIHVK--AHFDYDP 358
L + P V A D +P
Sbjct 551 LCRGYPLPFDPDDPNTSLVTSVAILDKEP 579
Score = 42.7 bits (99), Expect = 0.014, Method: Composition-based stats.
Identities = 25/156 (16%), Positives = 52/156 (33%), Gaps = 30/156 (19%)
Query 222 LAHDKVAEQEMQL----------EPITDERVYESIGQYGGETVKI------------VRI 259
+D A + + S Y +TV + V I
Sbjct 586 ETYDSPASHSSKTGKVSNMKDARPSSPADVASNSSHGYPNDTVSLASSIATQPELITVHI 645
Query 260 EKARDIPLGATVRNE--MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
K + G T+ + + +IV + + L EGD ++E+N ++ N+V
Sbjct 646 VKG-PMGFGFTIADSPGGGGQRVKQIVD---SPRCRGLKEGDLIVEVNKRNVQALTHNQV 701
Query 318 FDLLSD--MHGTLTFVLIPSQQIKPPPAKETVIHVK 351
D+L + +T ++ P + ++ +
Sbjct 702 VDMLIECPKGSEVTLLVQRGGLPVPKKSPKSQPLER 737
>sp|Q61235|SNTB2_MOUSE Beta-2-syntrophin OS=Mus musculus OX=10090
GN=Sntb2 PE=1 SV=2
Length=520
Score = 76.2 bits (186), Expect = 3e-13, Method: Composition-based stats.
Identities = 23/101 (23%), Positives = 48/101 (48%), Gaps = 3/101 (3%)
Query 252 ETVKIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEINGIE 308
V+ VR+ K LG +++ + ++IS+I G AA++S L GD +L +NG +
Sbjct 91 PPVRRVRVVKQEAGGLGISIKGGRENRMPILISKIFPGLAADQSRALRLGDAILSVNGTD 150
Query 309 IRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIH 349
+R ++ L + + +++ P K +++
Sbjct 151 LRQATHDQAVQALKRAGKEVLLEVKFIREVTPYIKKPSLVS 191
>sp|Q13425|SNTB2_HUMAN Beta-2-syntrophin OS=Homo sapiens OX=9606
GN=SNTB2 PE=1 SV=1
Length=540
Score = 76.2 bits (186), Expect = 3e-13, Method: Composition-based stats.
Identities = 23/101 (23%), Positives = 48/101 (48%), Gaps = 3/101 (3%)
Query 252 ETVKIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEINGIE 308
V+ VR+ K LG +++ + ++IS+I G AA++S L GD +L +NG +
Sbjct 111 PPVRRVRVVKQEAGGLGISIKGGRENRMPILISKIFPGLAADQSRALRLGDAILSVNGTD 170
Query 309 IRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIH 349
+R ++ L + + +++ P K +++
Sbjct 171 LRQATHDQAVQALKRAGKEVLLEVKFIREVTPYIKKPSLVS 211
>sp|Q8R3Z5|CACB1_MOUSE Voltage-dependent L-type calcium channel
subunit beta-1 OS=Mus musculus OX=10090 GN=Cacnb1 PE=1 SV=1
Length=597
Score = 76.6 bits (187), Expect = 3e-13, Method: Composition-based stats.
Identities = 63/386 (16%), Positives = 124/386 (32%), Gaps = 53/386 (14%)
Query 310 RGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCREL 369
+ E + L + + KP V+ + Y+PS VP + +
Sbjct 70 SDVSLEEDREALRKEAERQALAQLEKAKTKPVA-----FAVRTNVGYNPSPGDEVPVQGV 124
Query 370 GLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ-----QREAMKQTIE 424
++F+ D LH+ + + +WW G +P Q + ++Q
Sbjct 125 AITFEPKDFLHIKEKYNNDWWIGRLV---KEGCEVGFIPSPVKLDSLRLLQEQTLRQNRL 181
Query 425 EDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIIL 484
+ + R+ + K E + Y+ + RPIIL
Sbjct 182 SSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSM-------RPIIL 234
Query 485 IGPQNCG---QNELRQRLMNKEKDRFASAVPHTTR------SRRDQEVAGRDYHFVSRQA 535
+GP G + +++ L + K RF + T ++R + + R
Sbjct 235 VGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSN 294
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKI---CLLSLR-TQSLKTLRNSDLK 591
+ + E + + ++ + L L + L
Sbjct 295 TRSSL--------AEVQ--------SEIERIFELARTLQLVALDADTINHPAQLSKTSLA 338
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
P I++I S + L+ L+ GK + + L I + ++ Q FD + + L+ A
Sbjct 339 PIIVYIKITSPKVLQRLIKSRGK-SQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDA 397
Query 652 YQELLRLIN---KLDTEPQWVPSTWL 674
+ L + K P P L
Sbjct 398 CEHLAEYLEAYWKATHPPSSTPPNPL 423
>sp|Q12923|PTN13_HUMAN Tyrosine-protein phosphatase non-receptor
type 13 OS=Homo sapiens OX=9606 GN=PTPN13 PE=1 SV=2
Length=2485
Score = 77.4 bits (189), Expect = 4e-13, Method: Composition-based stats.
Identities = 39/259 (15%), Positives = 82/259 (32%), Gaps = 41/259 (16%)
Query 245 SIGQYGGETVKIVRIEKARDIPLGATV------RNEMDSVIISRIVKGGAAEKSGLLHEG 298
SI + +V ++K LG + + IS + GG A+ G L G
Sbjct 1082 SIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPG 1141
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDP 358
D ++ +N + + G + ++L + +T V+ ++ V +Y
Sbjct 1142 DRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYMK 1201
Query 359 S----DDPYVPCRELGLSFQKGDILHV---------------------------ISQEDP 387
D + + +G + H+ +SQ
Sbjct 1202 KSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQV 1261
Query 388 NWWQAYREGDEDNQPLAGLVPGKSFQ----QQREAMKQTIEEDKEPEKSGKLWCAKKNKK 443
N + A GD+ Q P S ++ + K+P S + +
Sbjct 1262 NGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGDS 1321
Query 444 KRKKVLYNANKNDDYDNEE 462
+ Y+++++ +E
Sbjct 1322 DMDEATYSSSQDHQTPKQE 1340
Score = 70.1 bits (170), Expect = 6e-11, Method: Composition-based stats.
Identities = 24/133 (18%), Positives = 54/133 (41%), Gaps = 10/133 (8%)
Query 222 LAHDKVAEQEMQLEPITDERVYESIGQYGGETVKI--VRIEKAR-DIPLGATVRNEM--- 275
H ++ +++ +++ + I V + K + + T
Sbjct 1332 QDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGISVTGGVNTSVR 1391
Query 276 -DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP 334
+ + ++ GAAE G +H+GD VL +NG+ + G + + L + + +L
Sbjct 1392 HGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLL-- 1449
Query 335 SQQIKPPPAKETV 347
++ + P +KE V
Sbjct 1450 -EKGQSPTSKEHV 1461
Score = 59.7 bits (143), Expect = 8e-08, Method: Composition-based stats.
Identities = 19/123 (15%), Positives = 45/123 (37%), Gaps = 3/123 (2%)
Query 222 LAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV--RNEMDSVI 279
H + + + + E ++ + K+ LG TV N+
Sbjct 1754 HIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLGFTVTKGNQRIGCY 1813
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
+ +++ A+ G L GD ++++N ++ + +LL T+ V+ ++
Sbjct 1814 VHDVIQD-PAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLELP 1872
Query 340 PPP 342
P
Sbjct 1873 RIP 1875
Score = 48.9 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 20/93 (22%), Positives = 37/93 (40%), Gaps = 10/93 (11%)
Query 249 YGGETVKIVRIEKARDIPLGATVRNEMDSV---------IISRIVKGGAAEKSGLLHEGD 299
E V++ K LG + E + + + ++ G A +SG + GD
Sbjct 1494 VTEENTFEVKLFKNSS-GLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGD 1552
Query 300 EVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+L++NG ++G EV L + +L
Sbjct 1553 VILKVNGASLKGLSQQEVISALRGTAPEVFLLL 1585
Score = 43.1 bits (100), Expect = 0.011, Method: Composition-based stats.
Identities = 17/88 (19%), Positives = 31/88 (35%), Gaps = 2/88 (2%)
Query 264 DIPLGATVRNE--MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
++ ++ V IS I A G L D + +NG+ +G + EV L
Sbjct 1892 ELGFSLCGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRAL 1951
Query 322 SDMHGTLTFVLIPSQQIKPPPAKETVIH 349
+L + P +K + +
Sbjct 1952 DMSLPSLVLKATRNDLPVVPSSKRSAVS 1979
>sp|Q99L88|SNTB1_MOUSE Beta-1-syntrophin OS=Mus musculus OX=10090
GN=Sntb1 PE=1 SV=4
Length=537
Score = 76.2 bits (186), Expect = 4e-13, Method: Composition-based stats.
Identities = 32/164 (20%), Positives = 64/164 (39%), Gaps = 15/164 (9%)
Query 222 LAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SV 278
A D A + ++ Q G V++ K LG +++ + +
Sbjct 82 QAPDSPAGVRTAFTDLPEQVPESISNQKRG-----VKVLKQELGGLGISIKGGKENKMPI 136
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
+IS+I KG AA+++ L+ GD +L +NG ++R +E L + + ++
Sbjct 137 LISKIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGKEVLLEVKYMREA 196
Query 339 KPPPAKETVIHVKAHFDYDPSDDPYV------PCRELGLSFQKG 376
P K + + ++ P + P + P SF +
Sbjct 197 TPYVKKGSPVSEIG-WETPPPESPRLGGGSAEPLSSQSFSFHRD 239
>sp|D2C357|PHNN_DICZ5 Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Dickeya zeae (strain Ech586) OX=590409 GN=phnN PE=3 SV=1
Length=188
Score = 71.6 bits (174), Expect = 4e-13, Method: Composition-based stats.
Identities = 30/158 (19%), Positives = 56/158 (35%), Gaps = 13/158 (8%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
R I L G G++ L L E R A + TR + G ++ +S F
Sbjct 3 RLIWLTGASGSGKDTLLDALRQTEPVRLLVAHRYITRPAQAG---GENHIALSEAEFAYR 59
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
F H + + YG I+ V +++G L + ++ + Y + P
Sbjct 60 REHNLFALHWQAHQYQYGIGIE-VDHWLSAG----LDVVVNGSRSHHQQAQQRYGSRLLP 114
Query 600 ----PSQERLRALLAKEGKNPKPEELREIIEKTREMEQ 633
S L L + G+ + + + ++ M+
Sbjct 115 VCLQVSAAVLAQRLRQRGREDEAQIALRL-QRADAMDI 151
>sp|P54283|CACB1_RAT Voltage-dependent L-type calcium channel
subunit beta-1 OS=Rattus norvegicus OX=10116 GN=Cacnb1 PE=1
SV=1
Length=597
Score = 76.2 bits (186), Expect = 4e-13, Method: Composition-based stats.
Identities = 63/386 (16%), Positives = 124/386 (32%), Gaps = 53/386 (14%)
Query 310 RGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCREL 369
+ E + L + + KP V+ + Y+PS VP + +
Sbjct 70 SDVSLEEDREALRKEAERQALAQLEKAKTKPVA-----FAVRTNVGYNPSPGDEVPVQGV 124
Query 370 GLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ-----QREAMKQTIE 424
++F+ D LH+ + + +WW G +P Q + ++Q
Sbjct 125 AITFEPKDFLHIKEKYNNDWWIGRLV---KEGCEVGFIPSPVKLDSLRLLQEQTLRQNRL 181
Query 425 EDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIIL 484
+ + R+ + K E + Y+ + RPIIL
Sbjct 182 SSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSM-------RPIIL 234
Query 485 IGPQNCG---QNELRQRLMNKEKDRFASAVPHTTR------SRRDQEVAGRDYHFVSRQA 535
+GP G + +++ L + K RF + T ++R + + R
Sbjct 235 VGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSN 294
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKI---CLLSLR-TQSLKTLRNSDLK 591
+ + E + + ++ + L L + L
Sbjct 295 TRSSL--------AEVQ--------SEIERIFELARTLQLVALDADTINHPAQLSKTSLA 338
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
P I++I S + L+ L+ GK + + L I + ++ Q FD + + L+ A
Sbjct 339 PIIVYIKITSPKVLQRLIKSRGK-SQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDA 397
Query 652 YQELLRLIN---KLDTEPQWVPSTWL 674
+ L + K P P L
Sbjct 398 CEHLAEYLEAYWKATHPPSRTPPNPL 423
>sp|A5G2M7|PHNN_ACICJ Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Acidiphilium cryptum (strain JF-5) OX=349163 GN=phnN PE=3
SV=1
Length=181
Score = 71.2 bits (173), Expect = 5e-13, Method: Composition-based stats.
Identities = 29/178 (16%), Positives = 56/178 (31%), Gaps = 19/178 (11%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNK--EKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
R ++++GP G++ + + + TR E D+ VS
Sbjct 2 PRSGRLVLVVGPSGAGKDTVLREARRRLGHAPDIVFPRRVITRPPDPAE----DHEPVSD 57
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
F+ F YG V +++G+I ++++ + R
Sbjct 58 DEFQRR----AFALSWSAHGLSYGIPASIVGD-LDAGRIVVVNVSRAIVADARRRFPCFV 112
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
+ A P+ L A LA + E + +E D + N +A
Sbjct 113 VAVTAAPAI--LAARLAVRRRETAAEIGARLARAAAPVEA------DAVVANETTPEA 162
>sp|Q86UL8|MAGI2_HUMAN Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 2 OS=Homo sapiens OX=9606
GN=MAGI2 PE=1 SV=3
Length=1455
Score = 76.6 bits (187), Expect = 5e-13, Method: Composition-based stats.
Identities = 31/121 (26%), Positives = 45/121 (37%), Gaps = 25/121 (21%)
Query 492 QNELRQRLMNKEKDR-FASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGE 550
+ + L +D + VP TTR ++ EV G DY F++ + F +G +E G
Sbjct 118 KGSVDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEDFMELEKSGALLESGT 177
Query 551 FEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP---PSQERLRA 607
+E N YGT LL++ Q I P PS E R
Sbjct 178 YEDNYYGTPKPPAEPA-----PLLLNVTDQ----------------ILPGATPSAEGKRK 216
Query 608 L 608
Sbjct 217 R 217
Score = 67.4 bits (163), Expect = 4e-10, Method: Composition-based stats.
Identities = 28/122 (23%), Positives = 51/122 (42%), Gaps = 11/122 (9%)
Query 236 PITDERVYESIGQYGGETVKIVRIEKARDIPLGATV-----RNEMDSVI-----ISRIVK 285
P ++ E + +T +V K + G + R E S I I RI+
Sbjct 901 PSSNASPPEGFASHSLQTSDVVIHRK-ENEGFGFVIISSLNRPESGSTITVPHKIGRIID 959
Query 286 GGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKE 345
G A++ L GD +L +NG I ++ L+ D ++T +IP +++ P +
Sbjct 960 GSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAP 1019
Query 346 TV 347
+
Sbjct 1020 SS 1021
Score = 62.0 bits (149), Expect = 2e-08, Method: Composition-based stats.
Identities = 31/134 (23%), Positives = 54/134 (40%), Gaps = 3/134 (2%)
Query 214 TPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRN 273
P L + E Q+ P T R+ S Y V + R+E +
Sbjct 739 KPDPYELYEKSRAIYESRQQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRI-LGGDE 797
Query 274 EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL--SDMHGTLTFV 331
++I ++ G+A++ G LH GDE++ ++GI + GK V DL+ + +G +
Sbjct 798 PGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLT 857
Query 332 LIPSQQIKPPPAKE 345
+ P E
Sbjct 858 VRRKVLCGGEPCPE 871
Score = 54.7 bits (130), Expect = 3e-06, Method: Composition-based stats.
Identities = 24/126 (19%), Positives = 45/126 (36%), Gaps = 21/126 (17%)
Query 231 EMQLEPITDERVYESIG---------QYGGETVK--------IVRIEKARDIPLGATVRN 273
+ Q P D R + QY + V +EK G ++R
Sbjct 1105 DYQQPPPLDYRQPPLLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGA-KGFGFSIRG 1163
Query 274 EMD---SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTF 330
+ + + R+ + G A ++G + GD+++EING R +L+ +
Sbjct 1164 GREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKSGGRRVRL 1223
Query 331 VLIPSQ 336
+L
Sbjct 1224 LLKRGT 1229
Score = 49.3 bits (116), Expect = 1e-04, Method: Composition-based stats.
Identities = 29/140 (21%), Positives = 49/140 (35%), Gaps = 5/140 (4%)
Query 235 EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGL 294
P+ D+ V + + + I K G T+ + + +I+ +
Sbjct 584 PPVHDDNVSMASSGATQAELMTLTIVKGAQ-GFGFTIADSPTGQRVKQILD---IQGCPG 639
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMH-GTLTFVLIPSQQIKPPPAKETVIHVKAH 353
L EGD ++EIN ++ EV D+L D G+ T ++I P I +
Sbjct 640 LCEGDLIVEINQQNVQNLSHTEVVDILKDCPIGSETSLIIHRGGFFSPWKTPKPIMDRWE 699
Query 354 FDYDPSDDPYVPCRELGLSF 373
P P L F
Sbjct 700 NQGSPQTSLSAPAIPQNLPF 719
Score = 43.9 bits (102), Expect = 0.006, Method: Composition-based stats.
Identities = 16/87 (18%), Positives = 34/87 (39%), Gaps = 5/87 (6%)
Query 261 KARDIPLGATV-RNEMDSVI--ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
K ++ G T+ + + ++ G A + G + GD ++ IN + + G +V
Sbjct 430 KKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADV 489
Query 318 FDLLS--DMHGTLTFVLIPSQQIKPPP 342
L + ++ VL + P
Sbjct 490 VKLFQSVPIGQSVNLVLCRGYPLPFDP 516
>sp|Q4WHP5|HSE1_ASPFU Class E vacuolar protein-sorting machinery
protein hse1 OS=Aspergillus fumigatus (strain ATCC MYA-4609
/ CBS 101355 / FGSC A1100 / Af293) OX=330879 GN=hse1 PE=3
SV=1
Length=584
Score = 75.9 bits (185), Expect = 6e-13, Method: Composition-based stats.
Identities = 46/189 (24%), Positives = 80/189 (42%), Gaps = 32/189 (17%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
SQ + P + TV V+A FD+ PS+ L F+KGDI+ V+ +WW+
Sbjct 186 SQAVPPGTSAATVSRVRALFDFQPSEPGE-------LQFRKGDIIAVLESVYKDWWKGSL 238
Query 395 EGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANK 454
G G+ P ++ + + ++ E + +++ KN +K +L +
Sbjct 239 RGQT------GIFPLNYVEKLPDPTVEELQR--EAQMEAEVFGQIKNVEKLLTLLSTRSS 290
Query 455 N-DDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPH 513
+ DNEEI + +L + R + I LIG +++KD F
Sbjct 291 ELNVQDNEEITSLYHSTL----SIRPKLIELIG------------KYSQKKDEFTQLNEK 334
Query 514 TTRSRRDQE 522
++RRD E
Sbjct 335 FIKARRDYE 343
>sp|A1DFN5|HSE1_NEOFI Class E vacuolar protein-sorting machinery
protein hse1 OS=Neosartorya fischeri (strain ATCC 1020 /
DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB
181) OX=331117 GN=hse1 PE=3 SV=1
Length=603
Score = 75.5 bits (184), Expect = 6e-13, Method: Composition-based stats.
Identities = 45/189 (24%), Positives = 79/189 (42%), Gaps = 32/189 (17%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
SQ + P + TV V+A FD+ PS+ L F+KGDI+ V+ +WW+
Sbjct 205 SQAVPPGTSAATVSRVRALFDFQPSEPGE-------LQFRKGDIIAVLESVYKDWWKGSL 257
Query 395 EGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANK 454
G G+ P ++ + + ++ E + +++ KN +K +L +
Sbjct 258 RGQT------GIFPLNYVEKLPDPTVEELQR--EAQMEAEVFGQIKNVEKLLTLLSTRSS 309
Query 455 NDDYDNEEILTYEEMSLYHQP-ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPH 513
+ + E E +LYH + R + I LIG +++KD F
Sbjct 310 ELNVQDNE----EITALYHSTLSIRPKLIELIG------------KYSQKKDEFTQLNEK 353
Query 514 TTRSRRDQE 522
++RRD E
Sbjct 354 FIKARRDYE 362
>sp|Q96QZ7|MAGI1_HUMAN Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 1 OS=Homo sapiens OX=9606
GN=MAGI1 PE=1 SV=3
Length=1491
Score = 76.2 bits (186), Expect = 6e-13, Method: Composition-based stats.
Identities = 30/84 (36%), Positives = 47/84 (56%), Gaps = 6/84 (7%)
Query 504 KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSV 563
+ + AVP TTRS R+ EV G DY+F++ + F +G +E G +E N YGT
Sbjct 135 DNLYRHAVPCTTRSPREGEVPGVDYNFLTVKEFLDLEQSGTLLEVGTYEGNYYGTPKPPS 194
Query 564 RQVINSGKICLLSLRTQSLKTLRN 587
+ V SGK+ + T +L +L++
Sbjct 195 QPV--SGKV----ITTDALHSLQS 212
Score = 72.0 bits (175), Expect = 1e-11, Method: Composition-based stats.
Identities = 19/63 (30%), Positives = 34/63 (54%), Gaps = 0/63 (0%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
I RI++G A++ G L GD +L +NG I K +++ +L+ + T+T +IP +
Sbjct 1038 IGRIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKEAGNTVTLRIIPGDESS 1097
Query 340 PPP 342
Sbjct 1098 NAT 1100
Score = 57.4 bits (137), Expect = 4e-07, Method: Composition-based stats.
Identities = 28/123 (23%), Positives = 48/123 (39%), Gaps = 15/123 (12%)
Query 243 YESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVL 302
++ + TV++ R K L R + + R+ + G AE+ G + GDE+L
Sbjct 1142 PQATQEQDFYTVELERGAKGFGFSLRG-GREYNMDLYVLRLAEDGPAERCGKMRIGDEIL 1200
Query 303 EINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDP 362
EING + + +L+ + + L P +YDPS D
Sbjct 1201 EINGETTKNMKHSRAIELIKNGGRRVRLFLKRGDGSVP--------------EYDPSSDR 1246
Query 363 YVP 365
+ P
Sbjct 1247 HGP 1249
Score = 54.7 bits (130), Expect = 3e-06, Method: Composition-based stats.
Identities = 20/79 (25%), Positives = 31/79 (39%), Gaps = 3/79 (4%)
Query 260 EKARDIPLGATVRNE-MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVF 318
K NE + + I IV GAA+ G L GDE++ ++G + GK V
Sbjct 846 RKETGFGFRILGGNEPGEPIYIGHIVPLGAADTDGRLRSGDELICVDGTPVIGKSHQLVV 905
Query 319 DLLSDM--HGTLTFVLIPS 335
L+ G + +
Sbjct 906 QLMQQAAKQGHVNLTVRRK 924
Score = 41.6 bits (96), Expect = 0.033, Method: Composition-based stats.
Identities = 25/127 (20%), Positives = 45/127 (35%), Gaps = 18/127 (14%)
Query 235 EPITDERVYESIGQYGGETVKI------------VRIEKARDIPLGATVRNE--MDSVII 280
+ S Y +TV + V I K + G T+ + +
Sbjct 610 PSSPADVASNSSHGYPNDTVSLASSIATQPELITVHIVKG-PMGFGFTIADSPGGGGQRV 668
Query 281 SRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
+IV + + L EGD ++E+N ++ N+V D+L + L+ + P
Sbjct 669 KQIVD---SPRCRGLKEGDLIVEVNKKNVQALTHNQVVDMLVECPKGSEVTLLVQRGGLP 725
Query 341 PPAKETV 347
P K
Sbjct 726 VPKKSPK 732
Score = 40.0 bits (92), Expect = 0.079, Method: Composition-based stats.
Identities = 19/104 (18%), Positives = 36/104 (35%), Gaps = 5/104 (5%)
Query 260 EKARDIPLGATVRNEMDSVI-ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVF 318
+ +R +E D + I +V G A G + GD ++ +N + G +V
Sbjct 477 KSSRGFGFTVVGGDEPDEFLQIKSLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVV 536
Query 319 DLLS--DMHGTLTFVLIPSQQIKPPPAKETVIHVK--AHFDYDP 358
+ + ++ L + P V A D +P
Sbjct 537 KIFQSIPIGASVDLELCRGYPLPFDPDDPNTSLVTSVAILDKEP 580
>sp|Q6RHR9|MAGI1_MOUSE Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 1 OS=Mus musculus OX=10090
GN=Magi1 PE=1 SV=1
Length=1471
Score = 76.2 bits (186), Expect = 6e-13, Method: Composition-based stats.
Identities = 21/90 (23%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query 257 VRIEKARDIPLGATV----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
V I + + G + RI++G A++ G L GD +L +NG I K
Sbjct 991 VEIRRGENEGFGFVIVSSVSRPEAGTTFGRIIEGSPADRCGKLKVGDRILAVNGCSITNK 1050
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPP 342
+++ +L+ + T+T +IP +
Sbjct 1051 SHSDIVNLIKEAGNTVTLRIIPGDESSNAT 1080
Score = 75.5 bits (184), Expect = 1e-12, Method: Composition-based stats.
Identities = 30/84 (36%), Positives = 46/84 (55%), Gaps = 6/84 (7%)
Query 504 KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSV 563
+ + AVP TTRS R+ EV G DY F++ + F +G +E G +E N YGT
Sbjct 135 DNLYRHAVPCTTRSPREGEVPGVDYSFLTVKEFLDLEQSGTLLEVGTYEGNYYGTPKPPS 194
Query 564 RQVINSGKICLLSLRTQSLKTLRN 587
+ V SGK+ + T +L +L++
Sbjct 195 QPV--SGKV----ITTDALHSLQS 212
Score = 58.5 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 28/117 (24%), Positives = 44/117 (38%), Gaps = 15/117 (13%)
Query 253 TVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
TV++ R K L R + + R+ + G AE+ G + GDE+LEING +
Sbjct 1132 TVELERGAKGFGFSLRG-GREYNMDLYVLRLAEDGPAERCGKMRIGDEILEINGETTKNM 1190
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCREL 369
+ +L+ + + L P +YDPS D P
Sbjct 1191 KHSRAIELIKNGGRRVRLFLRRGDGSVP--------------EYDPSSDRNGPSTGA 1233
Score = 54.7 bits (130), Expect = 3e-06, Method: Composition-based stats.
Identities = 20/79 (25%), Positives = 31/79 (39%), Gaps = 3/79 (4%)
Query 260 EKARDIPLGATVRNE-MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVF 318
K NE + + I IV GAA+ G L GDE++ ++G + GK V
Sbjct 838 RKETGFGFRILGGNEPGEPIYIGHIVPLGAADTDGRLRSGDELICVDGTPVIGKSHQLVV 897
Query 319 DLLSDM--HGTLTFVLIPS 335
L+ G + +
Sbjct 898 QLMQQAAKQGHVNLTVRRK 916
Score = 42.0 bits (97), Expect = 0.022, Method: Composition-based stats.
Identities = 25/149 (17%), Positives = 42/149 (28%), Gaps = 16/149 (11%)
Query 226 KVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKAR---------DIPLGATV-RNEM 275
V P E E+ Q + K + G TV +
Sbjct 424 VVPPVAPSHPPSNPEPARETPLQGKPFFTRNPSELKGKFIHTKLRKSSRGFGFTVVGGDE 483
Query 276 DSVI--ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS--DMHGTLTFV 331
I +V G A G + GD ++ +N + G +V + + ++
Sbjct 484 PDEFLQIKSLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVVKIFQSIPIGASVDLE 543
Query 332 LIPSQQIKPPPAKETVIHVK--AHFDYDP 358
L + P V A D +P
Sbjct 544 LCRGYPLPFDPDDPNTSLVTSVAILDKEP 572
Score = 41.6 bits (96), Expect = 0.032, Method: Composition-based stats.
Identities = 25/127 (20%), Positives = 45/127 (35%), Gaps = 18/127 (14%)
Query 235 EPITDERVYESIGQYGGETVKI------------VRIEKARDIPLGATVRNE--MDSVII 280
+ S Y +TV + V I K + G T+ + +
Sbjct 602 PSSPADVASNSSHGYPNDTVSLASSIATQPELITVHIVKG-PMGFGFTIADSPGGGGQRV 660
Query 281 SRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
+IV + + L EGD ++E+N ++ N+V D+L + L+ + P
Sbjct 661 KQIVD---SPRCRGLKEGDLIVEVNKKNVQALTHNQVVDMLIECPKGSEVTLLVQRGGLP 717
Query 341 PPAKETV 347
P K
Sbjct 718 VPKKSPK 724
>sp|Q9MZL3|CACB3_BOVIN Voltage-dependent L-type calcium channel
subunit beta-3 OS=Bos taurus OX=9913 GN=CACNB3 PE=2 SV=2
Length=484
Score = 75.1 bits (183), Expect = 7e-13, Method: Composition-based stats.
Identities = 59/341 (17%), Positives = 110/341 (32%), Gaps = 50/341 (15%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
QQ++ K V+ + Y D P + G++F+ D LH+ + +WW
Sbjct 49 QQQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRL 108
Query 395 EGDEDNQPLAGLVPGKSFQQQ-REAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNAN 453
+ + +P + R +Q P + R+ +
Sbjct 109 VKEGGD---IAFIPSPQRLESIRLKQEQKARRSGNPSSLSDIGS-------RRSPPPSLA 158
Query 454 KNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKEKDRFASA 510
K E I Y+ + RP++L+GP G + +++ L + K RF
Sbjct 159 KQKQKQAEHIPPYDVVPSM-------RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGR 211
Query 511 VPHTTR-------SRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSV 563
+ T R G+ R E A E +
Sbjct 212 ISITRVTADLSLAKRSVLNNPGK------RTIIERSSARSSIAEV-----------QSEI 254
Query 564 RQVINSGKI---CLLSLR-TQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPE 619
++ K +L L + L P I+F+ S + L+ L+ GK + +
Sbjct 255 ERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGK-SQMK 313
Query 620 ELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
L + ++ Q FD + + L+ A + L +
Sbjct 314 HLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLE 354
>sp|Q9NY99|SNTG2_HUMAN Gamma-2-syntrophin OS=Homo sapiens OX=9606
GN=SNTG2 PE=1 SV=2
Length=539
Score = 75.1 bits (183), Expect = 8e-13, Method: Composition-based stats.
Identities = 25/89 (28%), Positives = 46/89 (52%), Gaps = 3/89 (3%)
Query 247 GQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLE 303
G + G + V + + LG +++ + V+IS+I + AA+++G+L GD VL+
Sbjct 64 GSHQGRNRRTVTLRRQPVGGLGLSIKGGSEHNVPVVISKIFEDQAADQTGMLFVGDAVLQ 123
Query 304 INGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+NGI + EV LL + +T +
Sbjct 124 VNGIHVENATHEEVVHLLRNAGDEVTITV 152
>sp|Q9HD26|GOPC_HUMAN Golgi-associated PDZ and coiled-coil motif-containing
protein OS=Homo sapiens OX=9606 GN=GOPC PE=1 SV=1
Length=462
Score = 74.7 bits (182), Expect = 8e-13, Method: Composition-based stats.
Identities = 24/104 (23%), Positives = 44/104 (42%), Gaps = 3/104 (3%)
Query 234 LEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAE 290
++ G ++ V + K LG ++ + ++IS I G A+
Sbjct 266 MQAPPGHDQDSLKKSQGVGPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPAD 325
Query 291 KSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP 334
+ G LH GD +L +NG+ +R E +LS G + F ++
Sbjct 326 RCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVY 369
>sp|Q13884|SNTB1_HUMAN Beta-1-syntrophin OS=Homo sapiens OX=9606
GN=SNTB1 PE=1 SV=3
Length=538
Score = 75.1 bits (183), Expect = 9e-13, Method: Composition-based stats.
Identities = 31/161 (19%), Positives = 63/161 (39%), Gaps = 15/161 (9%)
Query 225 DKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIIS 281
D A + ++ Q G V++ K LG +++ + ++IS
Sbjct 86 DSPAGVRTAFTDLPEQVPESISNQKRG-----VKVLKQELGGLGISIKGGKENKMPILIS 140
Query 282 RIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
+I KG AA+++ L+ GD +L +NG ++R +E L + + ++ P
Sbjct 141 KIFKGLAADQTQALYVGDAILSVNGADLRDATHDEAVQALKRAGKEVLLEVKYMREATPY 200
Query 342 PAKETVIHVKAHFDYDPSDDPYV------PCRELGLSFQKG 376
K + + ++ P + P + P SF +
Sbjct 201 VKKGSPVSEIG-WETPPPESPRLGGSTSDPPSSQSFSFHRD 240
>sp|O55164|MPDZ_RAT Multiple PDZ domain protein OS=Rattus norvegicus
OX=10116 GN=Mpdz PE=1 SV=1
Length=2054
Score = 75.9 bits (185), Expect = 9e-13, Method: Composition-based stats.
Identities = 30/104 (29%), Positives = 49/104 (47%), Gaps = 1/104 (1%)
Query 229 EQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGA 288
Q ++L DE Y+ TV++ + + + L + V +S IVKGG
Sbjct 1685 PQRVRLTLYRDEAPYKEEDVCDTFTVEL-QKRPGKGLGLSIVGKRNDTGVFVSDIVKGGI 1743
Query 289 AEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
A+ G L +GD++L +NG ++R V LL GT+T +
Sbjct 1744 ADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVTLEV 1787
Score = 74.3 bits (181), Expect = 3e-12, Method: Composition-based stats.
Identities = 45/233 (19%), Positives = 83/233 (36%), Gaps = 17/233 (7%)
Query 112 LESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITV 171
LE+ + E L S LK D +++ +SLL ++Q+ F + ++
Sbjct 2 LETIDKNRALQAAERLQSKLKE----RGDVANEDKLSLLKSVLQSPLFSQILSLQTSLQQ 57
Query 172 HMNKASPPFPLISNA-QDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQ 230
++ + +NA + + + E +LL +P L A
Sbjct 58 LKDQVNVATLATANADHAHTPQFSSAIISNLQSE-----SLLLSPSNGNLEAISGPGAPP 112
Query 231 EMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV------RNEMDSVIISRIV 284
M +P +E G V+I + K LG +V + + I
Sbjct 113 AMDGKPACEELDQLIKSMAQGRHVEIFELLKPPCGGLGFSVVGLRSENRGELGIFVQEIQ 172
Query 285 KGGAAEKSGLLHEGDEVLEINGIEI-RGKDVNEVFDLLSDMHGTLTFVLIPSQ 336
+G A + G L E D++L ING + + + +L T+ V+
Sbjct 173 EGSVAHRDGRLKETDQILAINGQVLDQTITHQQAISILQKAKDTIQLVIARGS 225
Score = 72.8 bits (177), Expect = 8e-12, Method: Composition-based stats.
Identities = 18/101 (18%), Positives = 44/101 (44%), Gaps = 3/101 (3%)
Query 257 VRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
+ I R + + M + I +++ A K+G L GD ++E++G+++R +
Sbjct 1151 ISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRIVEVDGMDLRDASHEQ 1210
Query 317 VFDLLSDMHGTLTFV---LIPSQQIKPPPAKETVIHVKAHF 354
+ + + F+ ++ + P P+ ++ K F
Sbjct 1211 AVEAIRKAGSPVVFMVQSIVNRPRKSPLPSLPHSLYPKCSF 1251
Score = 68.9 bits (167), Expect = 1e-10, Method: Composition-based stats.
Identities = 30/135 (22%), Positives = 53/135 (39%), Gaps = 16/135 (12%)
Query 226 KVAEQEMQLEPITDERVYESIGQYGGETVK---------IVRIEKAR-DIPLGATVRNE- 274
A LEPI + + + + I K + + L ++
Sbjct 1574 TPAVPAPDLEPIPSTSRSSTPAIFASDPATCPIIPGCETTIEISKGQTGLGLSIVGGSDT 1633
Query 275 -MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
+ ++II + + GAA K G L GD++LE+NGI++R +E ++L + L
Sbjct 1634 LLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLY 1693
Query 334 PSQQIKPPPAKETVI 348
P KE +
Sbjct 1694 R----DEAPYKEEDV 1704
Score = 68.2 bits (165), Expect = 2e-10, Method: Composition-based stats.
Identities = 20/95 (21%), Positives = 40/95 (42%), Gaps = 7/95 (7%)
Query 245 SIGQYGGETVKIVRIEKARDIPLGATVRNEMD------SVIISRIVKGGAAEKSGLLHEG 298
G K + +++ D LG ++ + + + GAA + G L G
Sbjct 1960 FPDDLGPPQSKTITLDRGPD-GLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRG 2018
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
D+++ +NG + G E +L GT+T +++
Sbjct 2019 DQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVL 2053
Score = 63.2 bits (152), Expect = 8e-09, Method: Composition-based stats.
Identities = 16/101 (16%), Positives = 40/101 (40%), Gaps = 6/101 (6%)
Query 254 VKIVRIEKARDIPLGATVRNEMD------SVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
++ V I+K LG ++ + + I+ + G A ++ L GD ++ I G
Sbjct 1844 LRTVEIKKGPADALGLSIAGGVGSPLGDVPIFIAMMHPNGVAAQTQKLRVGDRIVTICGT 1903
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVI 348
G + +L+ + G++ ++ + + +
Sbjct 1904 STDGMTHTQAVNLMKNASGSIEVQVVAGGDVSVVTGHQQEL 1944
Score = 62.0 bits (149), Expect = 2e-08, Method: Composition-based stats.
Identities = 36/148 (24%), Positives = 59/148 (40%), Gaps = 22/148 (15%)
Query 254 VKIVRIEKARDIPLGATVRNEMDSV-------IISRIVKGGAAEKSGLLHEGDEVLEING 306
++ + +EK LG ++ + D + +I +V GG AEK G L GD ++ +N
Sbjct 690 IQAIELEKG-SRGLGFSILDYQDPIDPANTVIVIRSLVPGGIAEKDGRLFPGDRLMFVND 748
Query 307 IEIRGKDVNEVFDLLS-DMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVP 365
I + + E + L G + + KP P +V A D
Sbjct 749 INLENSTLEEAVEALKGAPSGMVRIGVA-----KPLPLSPEEGYVSA--KEDTFLCSPHT 801
Query 366 CRELGLS----FQKGDILHVISQEDPNW 389
C+E+GLS F+ L +I D
Sbjct 802 CKEMGLSDKALFRAD--LALIDTPDAES 827
Score = 60.8 bits (146), Expect = 3e-08, Method: Composition-based stats.
Identities = 18/84 (21%), Positives = 36/84 (43%), Gaps = 2/84 (2%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ G + + VI+ I+ GG A++ G L GD +L+I ++ G +V +L
Sbjct 265 GSGLGFGI-IGGKATGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVAQVL 323
Query 322 SDMHGTLTFVLIPSQ-QIKPPPAK 344
+ ++ + P P+
Sbjct 324 RQCGNRVKLMIARGAVEETPAPSS 347
Score = 60.8 bits (146), Expect = 4e-08, Method: Composition-based stats.
Identities = 33/154 (21%), Positives = 66/154 (43%), Gaps = 12/154 (8%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ + LG ++ + I ++ G SG L GDE+LE+NGI + G++ +V ++L
Sbjct 552 SENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGINLLGENHQDVVNIL 611
Query 322 SDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHV 381
++ +T V ++ + + D + ++ P++ E S + D +
Sbjct 612 KELPIDVTMVCCRRTVPPTALSEVDSLDIH---DLELTEKPHIDLGEFIGSSETEDPMLA 668
Query 382 ISQEDPN---------WWQAYREGDEDNQPLAGL 406
+S D N W+A + E + GL
Sbjct 669 MSDVDQNAEEIQTPLAMWEAGIQAIELEKGSRGL 702
Score = 58.1 bits (139), Expect = 3e-07, Method: Composition-based stats.
Identities = 25/157 (16%), Positives = 61/157 (39%), Gaps = 18/157 (11%)
Query 240 ERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEM---DSVIISRIVKGGAAEKSGLLH 296
+ + + V++ + + I + + ++ + + I K A E G +
Sbjct 364 DASTQKNEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVELDGRIQ 423
Query 297 EGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDY 356
GD+++ ++G ++G + ++L T+ L+ + ++E I +
Sbjct 424 IGDQIVAVDGTNLQGFTNQQAVEVLRHTGQTVRLTLM-----RKGASQEAEITSR----E 474
Query 357 DPSDDPYVPCR-----ELGLSFQKG-DILHVISQEDP 387
D + D +P E LS ++ IL + + P
Sbjct 475 DTAKDVDLPAENYEKDEESLSLKRSTSILPIEEEGYP 511
Score = 56.6 bits (135), Expect = 7e-07, Method: Composition-based stats.
Identities = 44/237 (19%), Positives = 83/237 (35%), Gaps = 17/237 (7%)
Query 106 TEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDI-SLLLQLVQNKDFQNAFK 164
+G+ L + + I S + + ++V+ + + SL L F +
Sbjct 1197 EVDGMDLRDASHEQAVEAIRKAGSPVVFMVQSIVNRPRKSPLPSLPHSLYPKCSFSSTNP 1256
Query 165 IHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAH 224
++ + +KA S L + E+++ P +
Sbjct 1257 FAESLQLTSDKAPSQSESESEKATL-----CSVPSSSPSVFSEMSSDYAQPSATTVAEDE 1311
Query 225 DKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD----SVII 280
DK E + + + E G G+ ++ +EK LG ++ D SV I
Sbjct 1312 DKEDEFGY-----SWKNIQERYGTLTGQLH-MIELEKGHS-GLGLSLAGNKDRTRMSVFI 1364
Query 281 SRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
I GAA + G L DE+LEING + G+ ++ + + I +
Sbjct 1365 VGIDPTGAAGRDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNAD 1421
Score = 53.1 bits (126), Expect = 8e-06, Method: Composition-based stats.
Identities = 31/164 (19%), Positives = 58/164 (35%), Gaps = 36/164 (22%)
Query 257 VRIEKARDIPLGATV--RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
+ + K + LG + + ++ V I + + G A K G L GD +L ++ + G +
Sbjct 1471 LELPKDQG-GLGIAICEEDTLNGVTIKSLTERGGAAKDGRLKPGDRILAVDDELVAGCPI 1529
Query 315 NEVFDLLSDMHGTLTFVL-----------------------------IPSQQIKPPPAKE 345
+ LL T+ + +P+ ++P P+
Sbjct 1530 EKFISLLKTAKTTVKLTVGAENPGCQAVPSAAVTASGERKDSSQTPAVPAPDLEPIPSTS 1589
Query 346 TVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDI---LHVISQED 386
A F DP+ P +P E + KG L ++ D
Sbjct 1590 RS-STPAIFASDPATCPIIPGCETTIEISKGQTGLGLSIVGGSD 1632
Score = 51.2 bits (121), Expect = 3e-05, Method: Composition-based stats.
Identities = 20/120 (17%), Positives = 46/120 (38%), Gaps = 6/120 (5%)
Query 227 VAEQEM-QLEPITDERVYESIGQYGGETV-KIVRIEKARD-IPLGATVRNEMDSVIISRI 283
VA + + + + + ++ E + V I K + + + + VI+ I
Sbjct 964 VAPKYLTEQSSLVSDAESVTLQSMSQEAFERTVTIAKGSSSLGMTVSANKDGLGVIVRSI 1023
Query 284 VKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD---MHGTLTFVLIPSQQIKP 340
+ GGA + G + GD +L IN + +L + + +P++ ++
Sbjct 1024 IHGGAISRDGRIAVGDCILSINEESTISLTNAQARAMLRRHSLIGPDIKITYVPAEHLEE 1083
>sp|Q66II3|GRB2_XENTR Growth factor receptor-bound protein 2 OS=Xenopus
tropicalis OX=8364 GN=grb2 PE=2 SV=1
Length=229
Score = 71.6 bits (174), Expect = 1e-12, Method: Composition-based stats.
Identities = 20/63 (32%), Positives = 30/63 (48%), Gaps = 7/63 (11%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+V+A FD+DP +D L F++GD + V+ DPNWW+ G P + P
Sbjct 172 YVQALFDFDPQEDGE-------LGFRRGDFIQVVDNSDPNWWKGTCLGQTGMFPRNYVTP 224
Query 409 GKS 411
Sbjct 225 VNR 227
Score = 41.2 bits (95), Expect = 0.015, Method: Composition-based stats.
Identities = 19/63 (30%), Positives = 32/63 (51%), Gaps = 14/63 (22%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE-DPNWWQAYREGDEDNQPLAGLVPGK 410
A +D+ + D LSF++GDIL V+++E D NW++A G + G +P
Sbjct 5 AKYDFKATADDE-------LSFKRGDILKVLNEECDQNWYKAELNGKD------GFIPKN 51
Query 411 SFQ 413
+
Sbjct 52 YIE 54
>sp|P54285|CACB3_MOUSE Voltage-dependent L-type calcium channel
subunit beta-3 OS=Mus musculus OX=10090 GN=Cacnb3 PE=1 SV=2
Length=484
Score = 74.3 bits (181), Expect = 1e-12, Method: Composition-based stats.
Identities = 59/341 (17%), Positives = 111/341 (33%), Gaps = 50/341 (15%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
QQ++ K V+ + Y D P + G++F+ D LH+ + +WW
Sbjct 49 QQQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRL 108
Query 395 EGDEDNQPLAGLVPGKSFQQQ-REAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNAN 453
+ + +P + R +Q P G + R+ +
Sbjct 109 VKEGGD---IAFIPSPQRLESIRLKQEQKARRSGNPSSLGDIGN-------RRSPPPSLA 158
Query 454 KNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKEKDRFASA 510
K E + Y+ + RP++L+GP G + +++ L + K RF
Sbjct 159 KQKQKQAEHVPPYDVVPSM-------RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGR 211
Query 511 VPHTTR-------SRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSV 563
+ T R G+ R E A E +
Sbjct 212 ISITRVTADLSLAKRSVLNNPGK------RTIIERSSARSSIAEV-----------QSEI 254
Query 564 RQVINSGKI---CLLSLR-TQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPE 619
++ K +L L + L P I+F+ S + L+ L+ GK + +
Sbjct 255 ERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGK-SQMK 313
Query 620 ELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
L + ++ Q FD + + L+ A + L +
Sbjct 314 HLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLE 354
>sp|Q6NBY8|PHNN_RHOPA Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
OX=258594 GN=phnN PE=3 SV=1
Length=194
Score = 70.9 bits (172), Expect = 1e-12, Method: Composition-based stats.
Identities = 37/198 (19%), Positives = 65/198 (33%), Gaps = 30/198 (15%)
Query 479 KRPIILIGPQNCGQNELRQR---LMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
R ++++GP G++ L L + A TR E + V+
Sbjct 17 GRLVLVVGPSGAGKDTLINAARTLCADDP-AIVFARRVVTREASAAEDNLQ----VTPDD 71
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICL-----LSLRTQSLKTLRNSDL 590
F AAG F H + YG + I +G+ + + + R++
Sbjct 72 FSRLEAAGDFALHWRAHGHAYGLPRG-LDDDIRAGRTVVANVSRMVIDPA-----RSAYA 125
Query 591 KPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVN--SDL 648
++ I P E L A +A + + H D I N +
Sbjct 126 NVVVVLITAP-AEVLAARIAARARASDGSITDRVG------RSVAAHP-DVTISNVGDPI 177
Query 649 DKAYQELLRLINKLDTEP 666
A ++LL +I +P
Sbjct 178 AHA-RDLLEIIRHGRPQP 194
>sp|P54286|CACB3_RABIT Voltage-dependent L-type calcium channel
subunit beta-3 OS=Oryctolagus cuniculus OX=9986 GN=CACNB3
PE=1 SV=1
Length=477
Score = 74.3 bits (181), Expect = 1e-12, Method: Composition-based stats.
Identities = 58/341 (17%), Positives = 110/341 (32%), Gaps = 50/341 (15%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
QQ++ K V+ + Y D P + G++F+ D LH+ + +WW
Sbjct 49 QQQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGINFEAKDFLHIKEKYSNDWWIGRL 108
Query 395 EGDEDNQPLAGLVPGKSFQQQ-REAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNAN 453
+ + +P + R +Q P + R+ +
Sbjct 109 VKEGGD---IAFIPSPQRLESIRLKQEQKARRSGNPSSLSDIGN-------RRSPPPSLA 158
Query 454 KNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKEKDRFASA 510
K E + Y+ + RP++L+GP G + +++ L + K RF
Sbjct 159 KQKQKQAEHVPPYDVVPSM-------RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGR 211
Query 511 VPHTTR-------SRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSV 563
+ T R G+ R E A E +
Sbjct 212 ISITRVTADLSLAKRSVLNNPGK------RTIIERSSARSSIAEV-----------QSEI 254
Query 564 RQVINSGKI---CLLSLR-TQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPE 619
++ K +L L + L P I+F+ S + L+ L+ GK + +
Sbjct 255 ERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGK-SQMK 313
Query 620 ELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
L + ++ Q FD + + L+ A + L +
Sbjct 314 HLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLE 354
>sp|Q8BH60|GOPC_MOUSE Golgi-associated PDZ and coiled-coil motif-containing
protein OS=Mus musculus OX=10090 GN=Gopc PE=1
SV=1
Length=463
Score = 74.3 bits (181), Expect = 1e-12, Method: Composition-based stats.
Identities = 24/104 (23%), Positives = 44/104 (42%), Gaps = 3/104 (3%)
Query 234 LEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAE 290
++ G ++ V + K LG ++ + ++IS I G A+
Sbjct 267 MQAPPGHDQDSLKKSQGVGPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPAD 326
Query 291 KSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP 334
+ G LH GD +L +NG+ +R E +LS G + F ++
Sbjct 327 RCGGLHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVY 370
>sp|Q4H4B6|SCRIB_DANRE Protein scribble homolog OS=Danio rerio
OX=7955 GN=scrib PE=1 SV=1
Length=1724
Score = 75.5 bits (184), Expect = 1e-12, Method: Composition-based stats.
Identities = 29/135 (21%), Positives = 51/135 (38%), Gaps = 9/135 (7%)
Query 221 LLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---- 276
L D +E + + + G ++ D LG ++
Sbjct 831 LRPEDDYFPRERRSSGLPFLLDPDCPAVSTGPAQRLATCLIRNDKGLGFSIAGGKGSTLY 890
Query 277 -----SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV 331
+ ISRI +GGAA + +L GD V+ ING+++ ++ LL+ T+T V
Sbjct 891 RVGDTGIFISRIAEGGAAHRDNILQVGDRVISINGVDMTEARHDQAVALLTGTSPTITLV 950
Query 332 LIPSQQIKPPPAKET 346
+ Q + T
Sbjct 951 VDREQSSVGGASPRT 965
Score = 67.8 bits (164), Expect = 3e-10, Method: Composition-based stats.
Identities = 24/136 (18%), Positives = 58/136 (43%), Gaps = 14/136 (10%)
Query 245 SIGQYGGETVKIVRIEKARDIPLGATVR-------NEMDSVIISRIVKGGAAEKSGLLHE 297
+ E + + + + + + + + + ISR+ + G A ++G +
Sbjct 721 EPARIEEEELTLSILRQTGGLGISIAGGKGSTPYKGDDEGIFISRVSEEGPAARAG-VKV 779
Query 298 GDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYD 357
GD++LE+NG+++ G + + + L + + ++ + ++P T ++ DY
Sbjct 780 GDKLLEVNGVDLHGAEHHTAVEALRNSGAAVVMTVLRERMVEPE-NAITTTPLRPEDDYF 838
Query 358 PSDDPYVPCRELGLSF 373
P + R GL F
Sbjct 839 PRE-----RRSSGLPF 849
Score = 65.5 bits (158), Expect = 1e-09, Method: Composition-based stats.
Identities = 32/117 (27%), Positives = 48/117 (41%), Gaps = 10/117 (9%)
Query 236 PITDERVYESIGQY---GGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKS 292
P+ DE E + G + IV P G V IS+++ G A +S
Sbjct 996 PMEDEYPIEEVTLIKAGGPLGLSIVGGSDHASHPFGI----NEPGVFISKVIPNGLASQS 1051
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIH 349
G L GD +LE+N I++R E L + ++ + PP +E VIH
Sbjct 1052 G-LRVGDRILEVNSIDLRHATHQEAVRALLSNKQEIRMLVR--RDPSPPGMQEIVIH 1105
Score = 62.0 bits (149), Expect = 2e-08, Method: Composition-based stats.
Identities = 25/126 (20%), Positives = 48/126 (38%), Gaps = 2/126 (2%)
Query 207 ELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIP 266
+L + ++ALL ++ ++ +P I + GE + I I
Sbjct 1066 DLRHATHQEAVRALLSNKQEI-RMLVRRDPSPPGMQEIVIHKQPGEKLGI-SIRGGAKGH 1123
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
G + + IS++ GAA + G L G +LE+ + G E +L
Sbjct 1124 AGNPFDPTDEGIFISKVSSNGAAARDGRLRVGMRILEVGNNSLLGMTHTEAVRVLRASGD 1183
Query 327 TLTFVL 332
+L ++
Sbjct 1184 SLVMLI 1189
>sp|P54287|CACB3_RAT Voltage-dependent L-type calcium channel
subunit beta-3 OS=Rattus norvegicus OX=10116 GN=Cacnb3 PE=1
SV=1
Length=484
Score = 74.3 bits (181), Expect = 1e-12, Method: Composition-based stats.
Identities = 59/341 (17%), Positives = 110/341 (32%), Gaps = 50/341 (15%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
QQ++ K V+ + Y D P + G++F+ D LH+ + +WW
Sbjct 49 QQQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRL 108
Query 395 EGDEDNQPLAGLVPGKSFQQQ-REAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNAN 453
+ + +P + R +Q P + R+ +
Sbjct 109 VKEGGD---IAFIPSPQRLESIRLKQEQKARRSGNPSSLSDIGN-------RRSPPPSLA 158
Query 454 KNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKEKDRFASA 510
K E + Y+ + RP++L+GP G + +++ L + K RF
Sbjct 159 KQKQKQAEHVPPYDVVPSM-------RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGR 211
Query 511 VPHTTR-------SRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSV 563
+ T R G+ R E A E +
Sbjct 212 ISITRVTADLSLAKRSVLNNPGK------RTIIERSSARSSIAEV-----------QSEI 254
Query 564 RQVINSGKI---CLLSLR-TQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPE 619
++ K +L L + L P I+F+ S + L+ L+ GK + +
Sbjct 255 ERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGK-SQMK 313
Query 620 ELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
L + ++ Q FD + + LD A + L +
Sbjct 314 HLTVQMMAYDKLVQCPPESFDVILDENQLDDACEHLAEYLE 354
>sp|E3G1M3|PHNN_ENTLS Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Enterobacter lignolyticus (strain SCF1) OX=701347 GN=phnN
PE=3 SV=1
Length=189
Score = 70.1 bits (170), Expect = 1e-12, Method: Composition-based stats.
Identities = 26/155 (17%), Positives = 51/155 (33%), Gaps = 12/155 (8%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+ I L+GP G++ L + L +E + A + TR +S F
Sbjct 3 GKLIWLVGPSGSGKDSLLEALRKQEHPQMLVAHRYITRPAGAGCENHVA---LSEHEFFT 59
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK----TLRNSDLKPYI 594
A F YG ++ + +++G L + + + + +
Sbjct 60 RAAQHLFALSWHANNLYYGVGME-IDLWLHAG----LDVVVNGSRAHLPQAKARYGESLL 114
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTR 629
S + LR L + G+ E + + R
Sbjct 115 PVCLQVSPDILRQRLEQRGRENALEIAQRLERAAR 149
>sp|O75970|MPDZ_HUMAN Multiple PDZ domain protein OS=Homo sapiens
OX=9606 GN=MPDZ PE=1 SV=2
Length=2070
Score = 75.1 bits (183), Expect = 1e-12, Method: Composition-based stats.
Identities = 30/129 (23%), Positives = 58/129 (45%), Gaps = 5/129 (4%)
Query 229 EQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGA 288
Q ++L DE Y+ T+++ + + + + L + V +S IVKGG
Sbjct 1701 PQRVRLTLYRDEAPYKEEEVCDTLTIEL-QKKPGKGLGLSIVGKRNDTGVFVSDIVKGGI 1759
Query 289 AEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQ----QIKPPPAK 344
A+ G L +GD++L +NG ++R V LL GT+T + + + P++
Sbjct 1760 ADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVTLEVGRIKAGPFHSERRPSQ 1819
Query 345 ETVIHVKAH 353
+ + +
Sbjct 1820 SSQVSEGSL 1828
Score = 71.2 bits (173), Expect = 3e-11, Method: Composition-based stats.
Identities = 37/218 (17%), Positives = 72/218 (33%), Gaps = 32/218 (15%)
Query 140 DSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLIS-----NAQDLAQEVQ 194
D +++ +SLL ++Q+ F + ++ ++ + S + L+ V
Sbjct 26 DVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQVNIATSATSNIEYAHVPHLSPAVI 85
Query 195 TVLKPVH-----HKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQY 249
L+ + E PHI +P DE
Sbjct 86 PTLQNESFLLSPNNGNLEALTGPGIPHING---------------KPACDEFDQLIKNMA 130
Query 250 GGETVKIVRIEKARDIPLGATV------RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLE 303
G V++ + K LG +V + + I +G A + G L E D++L
Sbjct 131 QGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDGRLKETDQILA 190
Query 304 INGIEI-RGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
ING + + + +L T+ V+ +
Sbjct 191 INGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQL 228
Score = 70.5 bits (171), Expect = 4e-11, Method: Composition-based stats.
Identities = 21/111 (19%), Positives = 48/111 (43%), Gaps = 4/111 (4%)
Query 257 VRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
+ I R + + M + I +++ A K+G L GD ++E++G+++R +
Sbjct 1164 ISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRIVEVDGMDLRDASHEQ 1223
Query 317 VFDLLSDMHGTLTFV---LIPSQQIKPPPAKETVIHVKAHFDY-DPSDDPY 363
+ + + F+ +I + P P+ ++ K +F +P D
Sbjct 1224 AVEAIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYPKYNFSSTNPFADSL 1274
Score = 67.4 bits (163), Expect = 3e-10, Method: Composition-based stats.
Identities = 23/113 (20%), Positives = 47/113 (42%), Gaps = 9/113 (8%)
Query 227 VAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD------SVII 280
A + +T +++ G K + +E+ D LG ++ + +
Sbjct 1960 PASSSLSFTGLTSSSIFQ--DDLGPPQCKSITLERGPD-GLGFSIVGGYGSPHGDLPIYV 2016
Query 281 SRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
+ GAA + G L GD+++ +NG + G E +L GT+T +++
Sbjct 2017 KTVFAKGAASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVL 2069
Score = 66.2 bits (160), Expect = 8e-10, Method: Composition-based stats.
Identities = 31/150 (21%), Positives = 55/150 (37%), Gaps = 11/150 (7%)
Query 225 DKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNE--MDSVIISR 282
+ + P + G I + + L ++ + ++II
Sbjct 1599 ESIRNTSRSSTPAIFASDPATCPIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHE 1658
Query 283 IVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPP 342
+ + GAA K G L GD++LE+NGI++R +E ++L + L P
Sbjct 1659 VYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYR----DEAP 1714
Query 343 AKETVIHVKAHFDYDPSDDPYVPCRELGLS 372
KE + + P + LGLS
Sbjct 1715 YKEEEVCDTLTIELQKK-----PGKGLGLS 1739
Score = 64.3 bits (155), Expect = 3e-09, Method: Composition-based stats.
Identities = 19/134 (14%), Positives = 49/134 (37%), Gaps = 11/134 (8%)
Query 254 VKIVRIEKARDIPLGATVRNEMD------SVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
++ V ++K LG ++ + + I+ + G A ++ L GD ++ I G
Sbjct 1860 LRTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGT 1919
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKE-----TVIHVKAHFDYDPSDDP 362
G + +LL + G++ ++ + + + + D
Sbjct 1920 STEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDD 1979
Query 363 YVPCRELGLSFQKG 376
P + ++ ++G
Sbjct 1980 LGPPQCKSITLERG 1993
Score = 60.5 bits (145), Expect = 5e-08, Method: Composition-based stats.
Identities = 24/139 (17%), Positives = 54/139 (39%), Gaps = 12/139 (9%)
Query 235 EPITDERVYESIGQYGGET----VKIVRIEKARDIPLGATVRNEM---DSVIISRIVKGG 287
T E ++ Q G E+ V++ + + I + + ++ + + I K
Sbjct 355 PTSTPELRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSS 414
Query 288 AAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQ--QIKPPPAKE 345
A E G + GD+++ ++G ++G + ++L T+ L+ Q ++E
Sbjct 415 AVEHDGRIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSRE 474
Query 346 TVIHVKAHFDYDPSDDPYV 364
V D P + +
Sbjct 475 D---VTKDADLSPVNASII 490
Score = 60.1 bits (144), Expect = 6e-08, Method: Composition-based stats.
Identities = 33/124 (27%), Positives = 51/124 (41%), Gaps = 16/124 (13%)
Query 257 VRIEKARDIPLGATVRNEMDSV-------IISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+ +EK LG ++ + D + II +V GG AEK G L GD ++ +N + +
Sbjct 701 IELEKG-SKGLGFSILDYQDPIDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNL 759
Query 310 RGKDVNEVFDLLS-DMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRE 368
+ E + L GT+ + KP P +V A D P C E
Sbjct 760 ENSSLEEAVEALKGAPSGTVRIGVA-----KPLPLSPEEGYVSA--KEDSFLYPPHSCEE 812
Query 369 LGLS 372
GL+
Sbjct 813 AGLA 816
Score = 60.1 bits (144), Expect = 7e-08, Method: Composition-based stats.
Identities = 16/74 (22%), Positives = 32/74 (43%), Gaps = 1/74 (1%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ G + + VI+ I+ GG A++ G L GD +L+I ++ G +V +L
Sbjct 264 GSGLGFGI-IGGKATGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVAQVL 322
Query 322 SDMHGTLTFVLIPS 335
+ ++
Sbjct 323 RQCGNRVKLMIARG 336
Score = 59.7 bits (143), Expect = 8e-08, Method: Composition-based stats.
Identities = 34/158 (22%), Positives = 66/158 (42%), Gaps = 20/158 (13%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ + LG ++ + I ++ G SG L GDE+LE+NGI + G++ +V ++L
Sbjct 560 SENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGITLLGENHQDVVNIL 619
Query 322 SDMHGTLTF-----VLIPSQQIKPPPAK--ETVIHVKAHFDY------DPSDDPYVPCRE 368
++ +T + P+ Q + + + K H D ++DP + +
Sbjct 620 KELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVDLGEFIGSSETEDPVLAMTD 679
Query 369 LGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGL 406
G S ++ Q W+A + E + GL
Sbjct 680 AGQS--TEEV-----QAPLAMWEAGIQHIELEKGSKGL 710
Score = 55.4 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 28/101 (28%), Positives = 43/101 (43%), Gaps = 6/101 (6%)
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD----SVIISRIVKGGAAEKSGLLH 296
+ E G GE ++ +EK LG ++ D SV I I GAA K G L
Sbjct 1336 NIRERYGTLTGELH-MIELEKGHS-GLGLSLAGNKDRSRMSVFIVGIDPNGAAGKDGRLQ 1393
Query 297 EGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
DE+LEING + G+ ++ + + I ++
Sbjct 1394 IADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKD 1434
Score = 49.7 bits (117), Expect = 1e-04, Method: Composition-based stats.
Identities = 19/83 (23%), Positives = 37/83 (45%), Gaps = 3/83 (4%)
Query 252 ETVKIVRIEKARDIPLGATVRNE--MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+ V+ + + K + LG + E + VII + + G A G L GD++L ++ +
Sbjct 1479 KNVQHLELPKDQG-GLGIAISEEDTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIV 1537
Query 310 RGKDVNEVFDLLSDMHGTLTFVL 332
G + + LL T+ +
Sbjct 1538 VGYPIEKFISLLKTAKMTVKLTI 1560
Score = 48.9 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 13/84 (15%), Positives = 33/84 (39%), Gaps = 3/84 (4%)
Query 260 EKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFD 319
+ + + + + +I+ I+ GGA + G + GD +L IN +
Sbjct 1013 KGNSSLGMTVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARA 1072
Query 320 LLSD---MHGTLTFVLIPSQQIKP 340
+L + + +P++ ++
Sbjct 1073 MLRRHSLIGPDIKITYVPAEHLEE 1096
>sp|Q925E0|SNTG2_MOUSE Gamma-2-syntrophin OS=Mus musculus OX=10090
GN=Sntg2 PE=1 SV=1
Length=539
Score = 74.3 bits (181), Expect = 1e-12, Method: Composition-based stats.
Identities = 31/127 (24%), Positives = 57/127 (45%), Gaps = 3/127 (2%)
Query 209 TALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLG 268
L + + L A+D + ++ I + V G G + V + + LG
Sbjct 26 KTALALLYDEGLENAYDVRLKLTKEVLTIQKQDVVCIGGAPPGANHRTVTLRRQPVGGLG 85
Query 269 ATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMH 325
+++ + V+IS+I K AA+++ +L GD VL++NGI + EV LL +
Sbjct 86 LSIKGGAEHGVPVVISKIFKDQAADQTEMLFIGDAVLQVNGINVENATHEEVVHLLRNAG 145
Query 326 GTLTFVL 332
+T +
Sbjct 146 DDVTITV 152
>sp|A9MGI9|PHNN_SALAR Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 /
RSK2980) OX=41514 GN=phnN PE=3 SV=1
Length=184
Score = 70.1 bits (170), Expect = 2e-12, Method: Composition-based stats.
Identities = 30/193 (16%), Positives = 61/193 (32%), Gaps = 28/193 (15%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+ I L+GP G++ L L +E ++ A + TR+ + +S+Q F
Sbjct 2 GKLIWLMGPSGSGKDSLLAELRQQEHEQLLIAHRYITRAANAGNEN---HIALSQQEFFI 58
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK------TLRN---SD 589
YG I+ + +++G + + R
Sbjct 59 RAKQNLLALSWYANGFYYGLGIE-IDLWLHAG----FDVVVNGSRAHLSQAQARYGTSLL 113
Query 590 LKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNS-DL 648
+ S + LR L G+ E + + + + N L
Sbjct 114 PVCLTV-----SPDILRQRLQTRGRENDAEIAARLERAA-----HYPPFNCHTVNNDGSL 163
Query 649 DKAYQELLRLINK 661
++ + LL L+ +
Sbjct 164 LQSVERLLILMGR 176
>sp|P54284|CACB3_HUMAN Voltage-dependent L-type calcium channel
subunit beta-3 OS=Homo sapiens OX=9606 GN=CACNB3 PE=1 SV=1
Length=484
Score = 73.9 bits (180), Expect = 2e-12, Method: Composition-based stats.
Identities = 58/341 (17%), Positives = 110/341 (32%), Gaps = 50/341 (15%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
QQ++ K V+ + Y D P + G++F+ D LH+ + +WW
Sbjct 49 QQQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRL 108
Query 395 EGDEDNQPLAGLVPGKSFQQQ-REAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNAN 453
+ + +P + R +Q P + R+ +
Sbjct 109 VKEGGD---IAFIPSPQRLESIRLKQEQKARRSGNPSSLSDIGN-------RRSPPPSLA 158
Query 454 KNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKEKDRFASA 510
K E + Y+ + RP++L+GP G + +++ L + K RF
Sbjct 159 KQKQKQAEHVPPYDVVPSM-------RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGR 211
Query 511 VPHTTR-------SRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSV 563
+ T R G+ R E A E +
Sbjct 212 ISITRVTADLSLAKRSVLNNPGK------RTIIERSSARSSIAEV-----------QSEI 254
Query 564 RQVINSGKI---CLLSLR-TQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPE 619
++ K +L L + L P I+F+ S + L+ L+ GK + +
Sbjct 255 ERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGK-SQMK 313
Query 620 ELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
L + ++ Q FD + + L+ A + L +
Sbjct 314 HLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLE 354
>sp|Q6GPJ9|GRB2B_XENLA Growth factor receptor-bound protein 2-B
OS=Xenopus laevis OX=8355 GN=grb2-b PE=1 SV=1
Length=229
Score = 70.9 bits (172), Expect = 2e-12, Method: Composition-based stats.
Identities = 20/63 (32%), Positives = 29/63 (46%), Gaps = 7/63 (11%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
V+A FD+DP +D L F++GD + V+ DPNWW+ G P + P
Sbjct 172 FVQALFDFDPQEDGE-------LGFRRGDFIQVVDNSDPNWWKGTCLGQTGMFPRNYVTP 224
Query 409 GKS 411
Sbjct 225 VNR 227
Score = 40.4 bits (93), Expect = 0.026, Method: Composition-based stats.
Identities = 18/63 (29%), Positives = 32/63 (51%), Gaps = 14/63 (22%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE-DPNWWQAYREGDEDNQPLAGLVPGK 410
A +D+ + D LSF++GD+L V+++E D NW++A G + G +P
Sbjct 5 AKYDFKATADDE-------LSFKRGDVLKVLNEECDQNWYKAELNGKD------GFIPKN 51
Query 411 SFQ 413
+
Sbjct 52 YIE 54
>sp|Q0CJU8|HSE1_ASPTN Class E vacuolar protein-sorting machinery
protein hse1 OS=Aspergillus terreus (strain NIH 2624 / FGSC
A1156) OX=341663 GN=hse1 PE=3 SV=1
Length=597
Score = 73.9 bits (180), Expect = 2e-12, Method: Composition-based stats.
Identities = 44/189 (23%), Positives = 78/189 (41%), Gaps = 32/189 (17%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
SQ + + TV V+A FD+ PS+ L F+KGD++ V+ +WW+
Sbjct 214 SQAVPSGTSAATVSRVRALFDFQPSEPGE-------LQFRKGDVIAVLESVYKDWWKGSL 266
Query 395 EGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANK 454
G G+ P ++ + + ++ E + +++ KN +K +L +
Sbjct 267 RGQT------GIFPLNYVEKLPDPTVEELQR--EAQMEAEVFGQIKNVEKLLTLLSTRSS 318
Query 455 NDDYDNEEILTYEEMSLYHQP-ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPH 513
+ + E E +LYH A R + I LIG +++KD F
Sbjct 319 EPNVQDNE----EITALYHSTLAIRPKLIELIG------------KYSQKKDEFTQLNEK 362
Query 514 TTRSRRDQE 522
++RRD E
Sbjct 363 FIKARRDYE 371
>sp|Q07883|GRB2_CHICK Growth factor receptor-bound protein 2 OS=Gallus
gallus OX=9031 GN=GRB2 PE=1 SV=1
Length=217
Score = 70.5 bits (171), Expect = 2e-12, Method: Composition-based stats.
Identities = 20/63 (32%), Positives = 30/63 (48%), Gaps = 7/63 (11%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+V+A FD+DP + E L F++GD + V+ DPNWW+ G P + P
Sbjct 160 YVQALFDFDPQE-------EGELGFRRGDFIQVLDNSDPNWWKGACHGQTGMFPRNYVTP 212
Query 409 GKS 411
Sbjct 213 VNR 215
Score = 40.0 bits (92), Expect = 0.031, Method: Composition-based stats.
Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 14/63 (22%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE-DPNWWQAYREGDEDNQPLAGLVPGK 410
A +D+ + D LSF++GDIL V+++E D NW++A G G +P
Sbjct 5 AKYDFKATADDE-------LSFKRGDILKVLNEECDQNWYKAELNGKG------GFIPKN 51
Query 411 SFQ 413
+
Sbjct 52 YIE 54
>sp|A2QW93|HSE1_ASPNC Class E vacuolar protein-sorting machinery
protein hse1 OS=Aspergillus niger (strain ATCC MYA-4892 /
CBS 513.88 / FGSC A1513) OX=425011 GN=hse1 PE=3 SV=1
Length=611
Score = 73.9 bits (180), Expect = 2e-12, Method: Composition-based stats.
Identities = 44/189 (23%), Positives = 77/189 (41%), Gaps = 32/189 (17%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
SQ + + TV V+A FD+ PS+ L F+KGD++ V+ +WW+
Sbjct 206 SQAVPSGTSAATVSRVRALFDFQPSEPGE-------LQFRKGDVIAVLESVYKDWWKGSL 258
Query 395 EGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANK 454
G G+ P ++ + + ++ E + ++ KN +K +L +
Sbjct 259 RGQT------GIFPLNYVEKLPDPTVEELQR--EAQMEADVFGQIKNVEKLLTLLSTRSS 310
Query 455 NDDYDNEEILTYEEMSLYHQP-ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPH 513
+ + E E +LYH A R + I LIG +++KD F
Sbjct 311 ELNVQDNE----EITALYHSTLAIRPKLIELIG------------KYSQKKDEFTQLNEK 354
Query 514 TTRSRRDQE 522
++RRD E
Sbjct 355 FIKARRDYE 363
>sp|F1MAD2|INADL_RAT InaD-like protein OS=Rattus norvegicus OX=10116
GN=Patj PE=1 SV=2
Length=1836
Score = 74.3 bits (181), Expect = 2e-12, Method: Composition-based stats.
Identities = 66/339 (19%), Positives = 122/339 (36%), Gaps = 41/339 (12%)
Query 22 DLASPEEHQKHREMAVDCPGDLGTRMMPIRRSAQLERIRQQQEDMRRRREEEG------- 74
DL E + +VD + +P R S++ E + Q +D +E+
Sbjct 1353 DLGGTEPVSSEEDSSVD------AKPLPERESSKPEDLTQAVDDSMVAEQEKASESPDSA 1406
Query 75 KKQELDLNSSMRLKKLAQIPPKTGI---DNPMFDTEEGIVLESPHYA-VKILEIEDLFSS 130
+Q S ++ +Q P + D ++P L ++
Sbjct 1407 ARQMKQPGYSAQVSSSSQEIPSAPAPLCQSTHADVTGSGNFQAPLSVDPAPLSVDPATCP 1466
Query 131 LKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLA 190
+ Q +++ L + +A IH V+ A+ + +
Sbjct 1467 IVPGQEMIIEISKGRSGLGLSIVGGKDTPLDAIVIHE---VYEEGAAARDGRLWAGDQIL 1523
Query 191 QEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYG 250
+ L+ H+E +TAL TP Q+++L DE Y
Sbjct 1524 EVNGVDLRSSSHEEA--ITALRQTP--------------QKVRLVIYRDEAQYRDEENLE 1567
Query 251 GETVKIVRIEKARDIPLGATV--RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIE 308
V +V ++K LG ++ + V IS IVKGGAA+ G L GD++L +NG +
Sbjct 1568 ---VFLVDLQKKTGRGLGLSIVGKRSGSGVFISDIVKGGAADLDGRLIRGDQILSVNGED 1624
Query 309 IRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV 347
+R V +L + G + + + +++T
Sbjct 1625 VRQASQETVATILKCVQGLVQLEIGRLRAGSWASSRKTS 1663
Score = 67.4 bits (163), Expect = 4e-10, Method: Composition-based stats.
Identities = 30/148 (20%), Positives = 53/148 (36%), Gaps = 17/148 (11%)
Query 227 VAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKG 286
++ + EP T E + E G V I + PLG + I+ I
Sbjct 1700 PPQKCTEEEPRTVEIIRELSDALG------VSIAGGKGSPLG------DIPIFIAMIQAN 1747
Query 287 GAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKET 346
G A ++ L GD ++ ING + G + +LL + G + ++ I +
Sbjct 1748 GVAARTQKLKVGDRIVSINGQPLDGLSHTDAVNLLKNAFGRIILQVVADTNISAIATQLE 1807
Query 347 VIHVKAH-----FDYDPSDDPYVPCREL 369
++ + D P D + R
Sbjct 1808 MMSAGSQLGSPTADRHPQDPEELLQRTA 1835
Score = 66.2 bits (160), Expect = 8e-10, Method: Composition-based stats.
Identities = 28/167 (17%), Positives = 61/167 (37%), Gaps = 19/167 (11%)
Query 193 VQTVLKPVHHKEGQELTALLNTPHIQ-------ALLLAHDKVAEQEMQLEPITDERVYES 245
V L V + QE L P + + + + A +L + E+
Sbjct 1006 VLVDLPAVTQRREQEELPLYRLPSARVVTKPSSHVGMVSSRHANAACELPEREEGEGEET 1065
Query 246 IGQYGGETVKIVRIEKARDIPLGATV------------RNEMDSVIISRIVKGGAAEKSG 293
+IV I + ++ LG ++ E+ + I ++++ A K+
Sbjct 1066 PNFSHWGPPRIVEIFREPNVSLGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTK 1125
Query 294 LLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
L GD++LE++G++++ E + + + FV+
Sbjct 1126 ALKTGDKILEVSGVDLQNASHAEAVEAIKSAGNPVVFVVQSLSSTPR 1172
Score = 64.7 bits (156), Expect = 2e-09, Method: Composition-based stats.
Identities = 36/202 (18%), Positives = 79/202 (39%), Gaps = 8/202 (4%)
Query 132 KHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQ 191
+HI++ ++ S + + ++++ I + A L N Q LA
Sbjct 130 RHIEYIDIERPSTGGLGFSVVALRSQSLG-LIDIFVKEVHPGSVADRDQRLKENDQILAI 188
Query 192 EVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGG 251
+ + + H++ L L++A + Q D + E++
Sbjct 189 NDTPLDQNISHQQAIALLQ--QATGSLRLVVAREVGHTQSRTSTSSADTTLPETVRWGHT 246
Query 252 ETVKIVRIEKARDIPLGATV-RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
E V+++ LG + + V++ IV GG A++ G L GD +L+I ++
Sbjct 247 EDVELI----NDGSGLGFGIVGGKSSGVVVRTIVPGGLADRDGRLQTGDHILKIGSTNVQ 302
Query 311 GKDVNEVFDLLSDMHGTLTFVL 332
G +V +L + ++ ++
Sbjct 303 GMTSEQVAQVLRNCGNSVRMLV 324
Score = 61.2 bits (147), Expect = 3e-08, Method: Composition-based stats.
Identities = 26/113 (23%), Positives = 50/113 (44%), Gaps = 6/113 (5%)
Query 229 EQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD----SVIISRIV 284
E+ + +TD+++ + GE I+ +EK ++ LG ++ D S+ + I
Sbjct 1221 EESEEDSALTDKKIRQRYADLPGELH-IIELEKDKN-GLGLSLAGNKDRSRMSIFVVGIN 1278
Query 285 KGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
G A G + GDE+LEIN + G+ ++ + V I ++
Sbjct 1279 PDGPAAADGRMRVGDELLEINNQILYGRSHQNASAIIKTAPTRVKLVFIRNED 1331
Score = 57.0 bits (136), Expect = 6e-07, Method: Composition-based stats.
Identities = 25/189 (13%), Positives = 69/189 (37%), Gaps = 16/189 (8%)
Query 190 AQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQY 249
+++V VL+ + + L+ + + + A + L + + +
Sbjct 306 SEQVAQVLRNCGNS----VRMLVARDPVGEIAVTPPTPASLPVALPVVATRTLGSDSSPF 361
Query 250 GGETVKIVRIEKARDIPLGATVR------NEMDSVIISRIVKGGAAEKSGLLHEGDEVLE 303
V++V+ + + + + E + + I+ G AA +G + D+++
Sbjct 362 ETYNVELVK-KDGQSLGIRIVGYVGTAHPGEASGIYVKSIIPGSAAYHNGQIQVNDKIVA 420
Query 304 INGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPY 363
++G+ I+G +V ++L + + L ++ + + ++ P
Sbjct 421 VDGVNIQGFANQDVVEVLRNAGQVVHLTL-----VRRKTSLSASPFEQPSSREAVAEPPE 475
Query 364 VPCRELGLS 372
VP L
Sbjct 476 VPELTGSLK 484
Score = 53.5 bits (127), Expect = 6e-06, Method: Composition-based stats.
Identities = 41/191 (21%), Positives = 72/191 (38%), Gaps = 32/191 (17%)
Query 169 ITVHMNKASPPFPLISNAQDLAQ-----EVQTVLKPVHHK-----EGQELTALLNTPHIQ 218
+ + ++ PF S+ + +A+ E+ LKP + E E L +Q
Sbjct 450 VRRKTSLSASPFEQPSSREAVAEPPEVPELTGSLKPETNSRMEAEEIGERLDNLRKDTVQ 509
Query 219 ALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIV------------RIEK-ARDI 265
A L D E + + + G +++ ++K ++ +
Sbjct 510 A-LEKPDVYPE---DIPGCPENELKSRWENLLGPDYEVMVATLDTQIADDEELQKYSKLL 565
Query 266 P-----LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDL 320
P LG V + IS I GG + LL DE+LE+NG+++ GK E
Sbjct 566 PIHTLRLGMEVDSFDGHHYISSIAPGGPVDTLNLLQPEDELLEVNGVQLYGKSRREAVSF 625
Query 321 LSDMHGTLTFV 331
L ++ T V
Sbjct 626 LKEVPPPFTLV 636
Score = 52.4 bits (124), Expect = 2e-05, Method: Composition-based stats.
Identities = 20/95 (21%), Positives = 38/95 (40%), Gaps = 8/95 (8%)
Query 242 VYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDS-------VIISRIVKGGAAEKSGL 294
+ VK V + K LG ++ + D ++I +V G AE+SG
Sbjct 673 DDDGELALWSPEVKTVELVK-DCKGLGFSILDYQDPLDPMRSVIVIRSLVADGVAERSGE 731
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLT 329
L GD ++ +N + + E ++L + +
Sbjct 732 LLPGDRLVSVNEFSLDNATLAEAVEVLKAVPPGVV 766
>sp|A1CEK6|HSE1_ASPCL Class E vacuolar protein-sorting machinery
protein hse1 OS=Aspergillus clavatus (strain ATCC 1007 /
CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612
GN=hse1 PE=3 SV=1
Length=599
Score = 73.6 bits (179), Expect = 2e-12, Method: Composition-based stats.
Identities = 44/188 (23%), Positives = 76/188 (40%), Gaps = 32/188 (17%)
Query 336 QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYRE 395
Q + + TV V+A FD+ PS+ L F+KGDI+ V+ +WW+
Sbjct 206 QAVPSGTSAATVSRVRALFDFQPSEPGE-------LQFRKGDIIAVLESVYKDWWKGSLR 258
Query 396 GDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKN 455
G G+ P ++ + + ++ E + ++ KN +K +L +
Sbjct 259 GQT------GIFPLNYVEKLPDPTVEELQR--EAQMEADVFGQIKNVEKLLTLLSTRSSE 310
Query 456 DDYDNEEILTYEEMSLYHQP-ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHT 514
+ + E E +LYH A R + I LIG +++KD F
Sbjct 311 LNVQDNE----EITALYHSTLAIRPKLIELIG------------KYSQKKDEFTQLNEKF 354
Query 515 TRSRRDQE 522
++RRD E
Sbjct 355 IKARRDYE 362
>sp|Q61234|SNTA1_MOUSE Alpha-1-syntrophin OS=Mus musculus OX=10090
GN=Snta1 PE=1 SV=1
Length=503
Score = 73.2 bits (178), Expect = 3e-12, Method: Composition-based stats.
Identities = 22/105 (21%), Positives = 44/105 (42%), Gaps = 3/105 (3%)
Query 239 DERVYESIGQYGGETVKIVRIEKARDIPLGATV---RNEMDSVIISRIVKGGAAEKSGLL 295
+ + + V + KA LG ++ R ++IS+I KG AA+++ L
Sbjct 64 PGAAPPQLPEALLLQRRRVTVRKADAGGLGISIKGGRENKMPILISKIFKGLAADQTEAL 123
Query 296 HEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
GD +L +NG ++ +E L + + +++ P
Sbjct 124 FVGDAILSVNGEDLSSATHDEAVQALKKTGKEVVLEVKYMKEVSP 168
>sp|Q1E878|HSE1_COCIM Class E vacuolar protein-sorting machinery
protein HSE1 OS=Coccidioides immitis (strain RS) OX=246410
GN=HSE1 PE=3 SV=1
Length=612
Score = 73.6 bits (179), Expect = 3e-12, Method: Composition-based stats.
Identities = 44/191 (23%), Positives = 78/191 (41%), Gaps = 34/191 (18%)
Query 334 PSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAY 393
PSQ I TV V+A +D+ PS+ L F+KGDI+ V+ +WW+
Sbjct 204 PSQGIPSGTTAATVSRVRALYDFQPSEPGE-------LQFRKGDIIAVLESVYKDWWKGS 256
Query 394 REGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNAN 453
G G+ P ++ + ++ ++ E + +++ KN +K +L ++
Sbjct 257 LRG------QVGIFPLNYVEKLSDPTQEELQR--EAQMEAEVFAEIKNVEKLLALLSTSS 308
Query 454 KNDDYDNEEILTYEEMSLYHQP--ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAV 511
+ EE++ + A R + I LIG +K+KD F
Sbjct 309 -----PELNVQENEEITKLYHSTLAIRPKLIELIG------------KYSKKKDDFTQLN 351
Query 512 PHTTRSRRDQE 522
++RRD E
Sbjct 352 EKFIKARRDYE 362
>sp|Q80U72|SCRIB_MOUSE Protein scribble homolog OS=Mus musculus
OX=10090 GN=Scrib PE=1 SV=2
Length=1612
Score = 73.9 bits (180), Expect = 3e-12, Method: Composition-based stats.
Identities = 25/82 (30%), Positives = 40/82 (49%), Gaps = 5/82 (6%)
Query 256 IVRIEKARDIPLGATVRNE-----MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
+VR EK + + + ISRI +GGAA ++G L GD VL ING+++
Sbjct 851 LVRSEKGLGFSIAGGKGSTPYRAGDGGIFISRIAEGGAAHRAGTLQVGDRVLSINGVDMT 910
Query 311 GKDVNEVFDLLSDMHGTLTFVL 332
+ LL+ T++ +L
Sbjct 911 EARHDHAVSLLTAASPTISLLL 932
Score = 66.2 bits (160), Expect = 8e-10, Method: Composition-based stats.
Identities = 32/135 (24%), Positives = 51/135 (38%), Gaps = 10/135 (7%)
Query 198 KPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIV 257
+ V QE + L P ++ LL + +P I + GE + I
Sbjct 1050 QDVREATHQEAVSALLRPCLELCLLV---------RRDPPPPGMRELCIQKAPGEKLGI- 1099
Query 258 RIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
I G + + IS++ GAA + G L G +LE+N + G E
Sbjct 1100 SIRGGAKGHAGNPCDPTDEGIFISKVSPTGAAGRDGRLRVGLRLLEVNQQSLLGLTHAEA 1159
Query 318 FDLLSDMHGTLTFVL 332
LL + TLT ++
Sbjct 1160 VQLLRSVGDTLTVLV 1174
Score = 64.3 bits (155), Expect = 3e-09, Method: Composition-based stats.
Identities = 24/125 (19%), Positives = 56/125 (45%), Gaps = 7/125 (6%)
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGAT-----VRNEMDSVIISRIVKGGAAEKSGLL 295
+ + + T+ IVR I + + + + + ISR+ + G A ++G +
Sbjct 702 LIEPARIEEEELTLTIVRQTGGLGISIAGGKGSTPYKGDDEGIFISRVSEEGPAARAG-V 760
Query 296 HEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFD 355
GD++LE+NG+ ++ + +E + L + + + ++P T+ ++ D
Sbjct 761 RVGDKLLEVNGVALQDAEHHEAVEALRGAGAAVQMRVWRERMVEPE-NAVTITPLRPEDD 819
Query 356 YDPSD 360
Y P +
Sbjct 820 YSPRE 824
Score = 60.1 bits (144), Expect = 7e-08, Method: Composition-based stats.
Identities = 19/73 (26%), Positives = 31/73 (42%), Gaps = 4/73 (5%)
Query 271 VRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTF 330
+ V IS+++ G A + G L GD +L +NG ++R E L L
Sbjct 1015 FGVQDPGVFISKVLPRGLAARCG-LRVGDRILAVNGQDVREATHQEAVSALLRPCLELCL 1073
Query 331 VLIPSQQIKPPPA 343
++ + PPP
Sbjct 1074 LVR---RDPPPPG 1083
>sp|Q63ZW7|INADL_MOUSE InaD-like protein OS=Mus musculus OX=10090
GN=Patj PE=1 SV=2
Length=1834
Score = 73.9 bits (180), Expect = 4e-12, Method: Composition-based stats.
Identities = 28/119 (24%), Positives = 49/119 (41%), Gaps = 9/119 (8%)
Query 222 LAH-DKVAEQEMQLE----PITDERVYESIGQYGGETVKIVRIEKAR-DIPLGATVRNE- 274
AH D Q P + G+ + I+ I K R + L +
Sbjct 1434 SAHADVTGSGNFQAPLPVDPAPLSVDPATCPIVPGQEM-IIEISKGRSGLGLSIVGGKDT 1492
Query 275 -MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+D+++I + + GAA + G L GD++LE+NG+++R E L + V+
Sbjct 1493 PLDAIVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRSSSHEEAITALRQTPQKVRLVV 1551
Score = 73.2 bits (178), Expect = 6e-12, Method: Composition-based stats.
Identities = 34/131 (26%), Positives = 57/131 (44%), Gaps = 5/131 (4%)
Query 222 LAHDKVAEQEMQLEPITDERVYESIGQYGGET---VKIVRIEKARDIPLGATV--RNEMD 276
+H++ Q VY QY E V +V ++K LG ++ +
Sbjct 1531 SSHEEAITALRQTPQKVRLVVYRDEAQYRDEENLEVFLVDLQKKTGRGLGLSIVGKRSGS 1590
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQ 336
V IS IVKGGAA+ G L GD++L +NG ++R V +L + G + + +
Sbjct 1591 GVFISDIVKGGAADLDGRLIRGDQILSVNGEDMRHASQETVATILKCVQGLVQLEIGRLR 1650
Query 337 QIKPPPAKETV 347
+++T
Sbjct 1651 AGSWAASRKTS 1661
Score = 66.6 bits (161), Expect = 5e-10, Method: Composition-based stats.
Identities = 24/146 (16%), Positives = 56/146 (38%), Gaps = 17/146 (12%)
Query 209 TALLNTP--HIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIP 266
++ P H+ + H A +L + E+ +IV I + ++
Sbjct 1028 ARVVTKPSSHMGLVSSRH---ANAACELPEREEGEGEETPNFSHWGPPRIVEIFREPNVS 1084
Query 267 LGATV------------RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
LG ++ E+ + I ++++ A K+ L GD++LE++G++++
Sbjct 1085 LGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTNALKTGDKILEVSGVDLQNASH 1144
Query 315 NEVFDLLSDMHGTLTFVLIPSQQIKP 340
E + + + FV+
Sbjct 1145 AEAVEAIKSAGNPVVFVVQSLSSTPR 1170
Score = 64.3 bits (155), Expect = 4e-09, Method: Composition-based stats.
Identities = 25/123 (20%), Positives = 47/123 (38%), Gaps = 12/123 (10%)
Query 227 VAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKG 286
++ + EP T E + E G + I + PLG + I+ I
Sbjct 1698 PPQKCTEEEPRTVEIIRELSDALG------ISIAGGKGSPLG------DIPIFIAMIQAN 1745
Query 287 GAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKET 346
G A ++ L GD ++ ING + G + +LL + G + ++ I +
Sbjct 1746 GVAARTQKLKVGDRIVSINGQPLDGLSHTDAVNLLKNAFGRIILQVVADTNISAIATQLE 1805
Query 347 VIH 349
++
Sbjct 1806 IMS 1808
Score = 63.9 bits (154), Expect = 4e-09, Method: Composition-based stats.
Identities = 36/202 (18%), Positives = 80/202 (40%), Gaps = 8/202 (4%)
Query 132 KHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQ 191
+H+++ ++ S + + ++++ I + A L N Q LA
Sbjct 130 RHVEYIDIERPSTGGLGFSVVALRSQSLG-LIDIFVKEVHPGSVADRDHRLKENDQILAI 188
Query 192 EVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGG 251
+ + + H++ L L++A + Q D + E++
Sbjct 189 NDTPLDQNISHQQAIALLQ--QATGSLRLVVAREVGHTQGRASTSSADTTLPETVCWGHT 246
Query 252 ETVKIVRIEKARDIPLGATV-RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
E V+++ LG + + V++ IV GG A++ G L GD +L+I G ++
Sbjct 247 EEVELI----NDGSGLGFGIVGGKSSGVVVRTIVPGGLADRDGRLQTGDHILKIGGTNVQ 302
Query 311 GKDVNEVFDLLSDMHGTLTFVL 332
G +V +L + ++ ++
Sbjct 303 GMTSEQVAQVLRNCGNSVRMLV 324
Score = 58.9 bits (141), Expect = 1e-07, Method: Composition-based stats.
Identities = 28/210 (13%), Positives = 75/210 (36%), Gaps = 12/210 (6%)
Query 190 AQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQY 249
+++V VL+ + + L+ + + + + L + + +
Sbjct 306 SEQVAQVLRNCGNS----VRMLVARDPVGEIAVTPPTPVSLPVALPAVATRTLDSDRSPF 361
Query 250 GGETVKIVRIEKARDIPLGATVR------NEMDSVIISRIVKGGAAEKSGLLHEGDEVLE 303
+V++V+ + + + + E + + I+ G AA +G + D+++
Sbjct 362 ETYSVELVK-KDGQSLGIRIVGYVGTAHPGEASGIYVKSIIPGSAAYHNGQIQVNDKIVA 420
Query 304 INGIEIRGKDVNEVFDLLSDMHGTLTFV-LIPSQQIKPPPAKETVIHVKAHFDYDPSDDP 362
++G+ I+G +V ++L + + + + P + + +
Sbjct 421 VDGVNIQGFANQDVVEVLRNAGQVVHLTLVRRKTSLSASPFEHSSSRETVAEPPKVPERA 480
Query 363 YVPCRELGLSFQKGDILHVISQEDPNWWQA 392
P E LS + +I + N QA
Sbjct 481 GSPKPEANLSVEAEEIGERLDNLKNNTVQA 510
Score = 57.4 bits (137), Expect = 5e-07, Method: Composition-based stats.
Identities = 25/106 (24%), Positives = 47/106 (44%), Gaps = 6/106 (6%)
Query 236 PITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD----SVIISRIVKGGAAEK 291
+TD+++ + GE I+ +EK ++ LG ++ D S+ + I G A
Sbjct 1226 ALTDKKIRQRYADLPGELH-IIELEKDKN-GLGLSLAGNKDRSRMSIFVVGINPEGPAAA 1283
Query 292 SGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
G + GDE+LEIN + G+ ++ + V I ++
Sbjct 1284 DGRMRIGDELLEINNQILYGRSHQNASAIIKTAPTRVKLVFIRNED 1329
Score = 53.5 bits (127), Expect = 7e-06, Method: Composition-based stats.
Identities = 23/117 (20%), Positives = 46/117 (39%), Gaps = 8/117 (7%)
Query 240 ERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDS-------VIISRIVKGGAAEKS 292
E + VK V + K LG ++ + D ++I +V G AE+S
Sbjct 672 EDDDDGELALWSPEVKTVELVK-DCKGLGFSILDYQDPLDPTRSVIVIRSLVADGVAERS 730
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIH 349
G L GD ++ +N + + E ++L + + + I ++ + +H
Sbjct 731 GELLPGDRLVSVNEFSLDNATLAEAVEVLKAVPPGVVHLGICKPLVEDEKEERFSLH 787
Score = 52.8 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 36/187 (19%), Positives = 68/187 (36%), Gaps = 5/187 (3%)
Query 174 NKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQ 233
+A P P + + + A+E+ L + + Q L P + +++ +
Sbjct 478 ERAGSPKPEANLSVE-AEEIGERLDNLKNNTVQALEKPDVYPE-KVPGSPENELKSRWEN 535
Query 234 LEPITDERVYESIGQYGGETVKIVRIEKARDIP---LGATVRNEMDSVIISRIVKGGAAE 290
L E + ++ + ++ + K I LG V + IS + GG +
Sbjct 536 LLGPDYEVMVATLDAQIADDEELQKYSKLLPIHTLRLGMEVDSFDGHHYISSVAPGGPVD 595
Query 291 KSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHV 350
LL DE+LE+NG+++ GK E L ++ T V E
Sbjct 596 TLNLLQPEDELLEVNGMQLYGKSRREAVSFLKEVPPPFTLVCCRRLFDDEASVDEPRTME 655
Query 351 KAHFDYD 357
A + +
Sbjct 656 PALLEAE 662
>sp|Q8VBX6|MPDZ_MOUSE Multiple PDZ domain protein OS=Mus musculus
OX=10090 GN=Mpdz PE=1 SV=2
Length=2055
Score = 73.6 bits (179), Expect = 4e-12, Method: Composition-based stats.
Identities = 28/104 (27%), Positives = 48/104 (46%), Gaps = 1/104 (1%)
Query 229 EQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGA 288
Q ++L DE Y+ T+++ + + + L + V +S IVKGG
Sbjct 1686 PQRVRLTLYRDEAPYKEEDVCDTFTIEL-QKRPGKGLGLSIVGKRNDTGVFVSDIVKGGI 1744
Query 289 AEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
A+ G L +GD++L +NG ++R V LL G +T +
Sbjct 1745 ADADGRLMQGDQILMVNGEDVRHATQEAVAALLKCSLGAVTLEV 1788
Score = 72.4 bits (176), Expect = 9e-12, Method: Composition-based stats.
Identities = 21/111 (19%), Positives = 47/111 (42%), Gaps = 4/111 (4%)
Query 257 VRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
+ I R + + M + I +++ A K+G L GD ++E++G+++R +
Sbjct 1152 ISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRIIEVDGMDLRDASHEQ 1211
Query 317 VFDLLSDMHGTLTFV---LIPSQQIKPPPAKETVIHVKAHFDY-DPSDDPY 363
+ + + F+ +I + P P+ ++ K F +P D
Sbjct 1212 AVEAIRKAGNPVVFMVQSIINRPRKSPLPSLPHSLYPKYSFSSTNPFADSL 1262
Score = 71.2 bits (173), Expect = 2e-11, Method: Composition-based stats.
Identities = 44/233 (19%), Positives = 82/233 (35%), Gaps = 17/233 (7%)
Query 112 LESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITV 171
LE+ + E L S LK D +++ +SLL ++Q+ F + ++
Sbjct 2 LETIDKNRALQAAERLQSKLKE----RGDVANEDKLSLLKSVLQSPLFSQILNLQTSLQQ 57
Query 172 HMNKAS-PPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQ 230
++ + + + + + E +LL +P+ L A
Sbjct 58 LKDQVNIATLATAAADHAHTPQFSSAVISNLQSE-----SLLLSPNHGNLEALPGPGAPA 112
Query 231 EMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV------RNEMDSVIISRIV 284
M +P DE G V+I + K LG +V + + I
Sbjct 113 VMDGKPTCDELDQLIKNMAQGRHVEIFELLKPPCGGLGFSVVGLRSENRGELGIFVQEIQ 172
Query 285 KGGAAEKSGLLHEGDEVLEINGIEI-RGKDVNEVFDLLSDMHGTLTFVLIPSQ 336
+G A + G L E D++L ING + + + +L T+ V+
Sbjct 173 EGSVAHRDGRLKETDQILAINGQVLDQTITHQQAISILQKAKDTVQLVIARGS 225
Score = 69.7 bits (169), Expect = 8e-11, Method: Composition-based stats.
Identities = 35/159 (22%), Positives = 60/159 (38%), Gaps = 21/159 (13%)
Query 226 KVAEQEMQLEPITDERVYESIGQYGGETVK---------IVRIEKAR-DIPLGATVRNE- 274
A LEPI + + + + I K + + L ++
Sbjct 1575 TPAVPAPDLEPIPSTSRSSTPAVFASDPATCPIIPGCETTIEISKGQTGLGLSIVGGSDT 1634
Query 275 -MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
+ ++II + + GAA K G L GD++LE+NGI++R +E ++L + L
Sbjct 1635 LLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLY 1694
Query 334 PSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLS 372
P KE + + P + LGLS
Sbjct 1695 R----DEAPYKEEDVCDTFTIELQKR-----PGKGLGLS 1724
Score = 68.2 bits (165), Expect = 2e-10, Method: Composition-based stats.
Identities = 20/95 (21%), Positives = 40/95 (42%), Gaps = 7/95 (7%)
Query 245 SIGQYGGETVKIVRIEKARDIPLGATVRNEMD------SVIISRIVKGGAAEKSGLLHEG 298
G K + +++ D LG ++ + + + GAA + G L G
Sbjct 1961 FPDDLGPPQSKTITLDRGPD-GLGFSIVGGYGSPHGDLPIYVKTVFAKGAAAEDGRLKRG 2019
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
D+++ +NG + G E +L GT+T +++
Sbjct 2020 DQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVL 2054
Score = 64.3 bits (155), Expect = 3e-09, Method: Composition-based stats.
Identities = 19/129 (15%), Positives = 47/129 (36%), Gaps = 14/129 (11%)
Query 234 LEPITDERVYESIGQYGGET--------VKIVRIEKARDIPLGATVRNEMD------SVI 279
P++ ES+ + ++ V I+K LG ++ + +
Sbjct 1817 TPPLSGINTSESLESNSKKNALASEIQGLRTVEIKKGPADSLGLSIAGGVGSPLGDVPIF 1876
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
I+ + G A ++ L GD ++ I G G + +L+ + G++ ++ +
Sbjct 1877 IAMMHPNGVAAQTQKLRVGDRIVTICGTSTDGMTHTQAVNLMKNASGSIEVQVVAGGDVS 1936
Query 340 PPPAKETVI 348
+ +
Sbjct 1937 VVTGHQQEL 1945
Score = 62.4 bits (150), Expect = 1e-08, Method: Composition-based stats.
Identities = 36/145 (25%), Positives = 56/145 (39%), Gaps = 22/145 (15%)
Query 257 VRIEKARDIPLGATVRNEMDSV-------IISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+ +EK LG ++ + D + +I +V GG AEK G L GD ++ +N I +
Sbjct 694 IELEKG-SRGLGFSILDYQDPIDPANTVIVIRSLVPGGIAEKDGRLFPGDRLMFVNDINL 752
Query 310 RGKDVNEVFDLLS-DMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRE 368
+ E + L G + + KP P +V A D C+E
Sbjct 753 ENSTLEEAVEALKGAPSGMVRIGVA-----KPLPLSPEEGYVSA--KEDAFLCSPHACKE 805
Query 369 LGLS----FQKGDILHVISQEDPNW 389
GLS F+ L +I D
Sbjct 806 SGLSDKALFRAD--LALIDTPDAES 828
Score = 62.4 bits (150), Expect = 1e-08, Method: Composition-based stats.
Identities = 17/84 (20%), Positives = 35/84 (42%), Gaps = 1/84 (1%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ G + + VI+ I+ GG A++ G L GD +L+I ++ G +V +L
Sbjct 265 GSGLGFGI-IGGKATGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVAQVL 323
Query 322 SDMHGTLTFVLIPSQQIKPPPAKE 345
+ ++ + P +
Sbjct 324 RQCGNRVKLMIARGAVEETPASSS 347
Score = 60.1 bits (144), Expect = 6e-08, Method: Composition-based stats.
Identities = 33/154 (21%), Positives = 66/154 (43%), Gaps = 12/154 (8%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ + LG ++ + I ++ G SG L GDE+LE+NGI + G++ +V ++L
Sbjct 553 SENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGINLLGENHQDVVNIL 612
Query 322 SDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHV 381
++ +T V ++ + + D + ++ P++ E S + D +
Sbjct 613 KELPIDVTMVCCRRTVPPIALSEMDSLDIN---DLELTEKPHIDLGEFIGSSETEDPMLA 669
Query 382 ISQEDPN---------WWQAYREGDEDNQPLAGL 406
+S D N W+A + E + GL
Sbjct 670 MSDVDQNAEEIQTPLAMWEAGGQSIELEKGSRGL 703
Score = 59.7 bits (143), Expect = 1e-07, Method: Composition-based stats.
Identities = 42/237 (18%), Positives = 86/237 (36%), Gaps = 17/237 (7%)
Query 106 TEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDI-SLLLQLVQNKDFQNAFK 164
+G+ L + + I + + + ++++ + + SL L F +
Sbjct 1198 EVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRKSPLPSLPHSLYPKYSFSSTNP 1257
Query 165 IHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAH 224
+++ + ++A + L + P E+ + P A+
Sbjct 1258 FADSLQLTTDQAPSQSESETEKPAL-----CNVPPSSPSVFSEMGSDCAQPSATAVSEDE 1312
Query 225 DKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD----SVII 280
DK E + + + E G G+ ++ +EK + LG ++ D SV I
Sbjct 1313 DKEDEFGY-----SWKNIQERYGSLTGQLH-VIELEKGQS-GLGLSLAGNKDRTRMSVFI 1365
Query 281 SRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
I GAA + G L DE+LEING + G+ ++ + + I +
Sbjct 1366 VGIDPTGAAGRDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNAD 1422
Score = 58.1 bits (139), Expect = 3e-07, Method: Composition-based stats.
Identities = 15/113 (13%), Positives = 44/113 (39%), Gaps = 5/113 (4%)
Query 240 ERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEM---DSVIISRIVKGGAAEKSGLLH 296
+ + + V++ + + I + + ++ + + I K A E G +
Sbjct 365 DASTQKNDESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDGRIQ 424
Query 297 EGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP--SQQIKPPPAKETV 347
GD+++ ++G ++G + ++L T+ L+ + Q ++
Sbjct 425 IGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVRLTLMRKGASQEAELTSRGDT 477
Score = 53.5 bits (127), Expect = 7e-06, Method: Composition-based stats.
Identities = 36/209 (17%), Positives = 76/209 (36%), Gaps = 12/209 (6%)
Query 141 SQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPP---FPLISNAQDLAQEVQTVL 197
+ S E + L ++ QN + +A + + P FP+ A E +
Sbjct 879 TSSSEVVLGLHLSLEELYTQNLLQRQHAGSPPTDMRPAPTSGFPISDYTTTNAVEQKYEC 938
Query 198 KPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEM-QLEPITDERVYESIGQYGGETV-K 255
+L + L+T + L A VA++ + + + ++ E +
Sbjct 939 ANPVAWPHSQLPSSLSTSELAPALPA---VAQKYLTDQSSLASDAESVNLQSMSQEAFER 995
Query 256 IVRIEKARD-IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
V I K + + + + VI+ I+ GGA + G + GD +L IN
Sbjct 996 TVTIAKGSSSLGMTVSANKDGLGVIVRSIIHGGAISRDGRIAVGDCILSINEESTISLTN 1055
Query 315 NEVFDLLSD---MHGTLTFVLIPSQQIKP 340
+ +L + + +P++ ++
Sbjct 1056 AQARAMLRRHSLIGPDIKITYVPAEHLEE 1084
Score = 52.4 bits (124), Expect = 2e-05, Method: Composition-based stats.
Identities = 32/164 (20%), Positives = 59/164 (36%), Gaps = 36/164 (22%)
Query 257 VRIEKARDIPLGATV--RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
+ + K + LG + + ++ V+I + + G A K G L GD +L ++ + G V
Sbjct 1472 LELPKDQG-GLGIAICEEDTINGVMIESLTEHGGAAKDGRLKPGDHILAVDDEVVAGCPV 1530
Query 315 NEVFDLLSDMHGTLTFVL-----------------------------IPSQQIKPPPAKE 345
+ LL T+ + +P+ ++P P+
Sbjct 1531 EKFISLLKTAKATVKLTVRAENPACPAVPSSAVTVSGERKDNSQTPAVPAPDLEPIPSTS 1590
Query 346 TVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDI---LHVISQED 386
A F DP+ P +P E + KG L ++ D
Sbjct 1591 RS-STPAVFASDPATCPIIPGCETTIEISKGQTGLGLSIVGGSD 1633
>sp|Q0P5E6|SNTA1_BOVIN Alpha-1-syntrophin OS=Bos taurus OX=9913
GN=SNTA1 PE=2 SV=1
Length=505
Score = 72.4 bits (176), Expect = 5e-12, Method: Composition-based stats.
Identities = 25/120 (21%), Positives = 52/120 (43%), Gaps = 7/120 (6%)
Query 228 AEQEMQLEPITDERVYESIGQYGGETV----KIVRIEKARDIPLGATV---RNEMDSVII 280
A++E + + + E + + V + KA LG ++ R ++I
Sbjct 55 AQREPEPAQLNGAAEPGAASPPLPEALLLQPRRVTVRKADAGGLGISIKGGRENKMPILI 114
Query 281 SRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
S+I KG AA+++ L GD +L +NG ++ +E +L + + +++ P
Sbjct 115 SKIFKGLAADQTEALFVGDAILSVNGEDLSSATHDEAVQVLKKTGKEVVLEVKYMKEVSP 174
>sp|Q28626|SNTA1_RABIT Alpha-1-syntrophin OS=Oryctolagus cuniculus
OX=9986 GN=SNTA1 PE=1 SV=1
Length=505
Score = 72.4 bits (176), Expect = 5e-12, Method: Composition-based stats.
Identities = 22/105 (21%), Positives = 44/105 (42%), Gaps = 3/105 (3%)
Query 239 DERVYESIGQYGGETVKIVRIEKARDIPLGATV---RNEMDSVIISRIVKGGAAEKSGLL 295
+ + + V + KA LG ++ R ++IS+I KG AA+++ L
Sbjct 70 PGAAPPQLPEALLLQRRRVTVRKADAGGLGISIKGGRENKMPILISKIFKGLAADQTEAL 129
Query 296 HEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
GD +L +NG ++ +E L + + +++ P
Sbjct 130 FVGDAILSVNGEDLSSATHDEAVQALKKTGKEVVLEVKYMKEVSP 174
>sp|Q5BBL4|HSE1_EMENI Class E vacuolar protein-sorting machinery
protein hse1 OS=Emericella nidulans (strain FGSC A4 / ATCC
38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=hse1 PE=3
SV=1
Length=581
Score = 72.4 bits (176), Expect = 5e-12, Method: Composition-based stats.
Identities = 40/193 (21%), Positives = 78/193 (40%), Gaps = 32/193 (17%)
Query 331 VLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW 390
P+ + + TV V+A +D+ PS+ L F+KGD++ V+ +WW
Sbjct 201 QAAPAGPVPSGTSAATVSRVRALYDFQPSEPGE-------LQFRKGDVIAVLESVYKDWW 253
Query 391 QAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLY 450
+ G G+ P ++ + + ++ E + +++ KN +K +L
Sbjct 254 KGSLRGQT------GIFPLNYVEKLPDPTVEELQR--EAQMEAEVFGQIKNVEKLLTLLS 305
Query 451 NANKN-DDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFAS 509
+ + +NEEI +L + R + + LIG +++KD F
Sbjct 306 TRSSELNVQENEEITNLYNSTL----SIRPKLVELIG------------KYSQKKDEFTQ 349
Query 510 AVPHTTRSRRDQE 522
++RRD E
Sbjct 350 LNEKFIKARRDYE 362
>sp|Q7CKG8|PHNN_YERPE Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Yersinia pestis OX=632 GN=phnN PE=3 SV=1
Length=193
Score = 68.5 bits (166), Expect = 6e-12, Method: Composition-based stats.
Identities = 30/165 (18%), Positives = 51/165 (31%), Gaps = 18/165 (11%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
R I L+GP G++ L L N A + TR +S+Q F
Sbjct 3 RLIYLMGPSGAGKDCLLSALRNATPQNRVVAHRYITRPADAGAENHVA---LSKQEFIQR 59
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS-------LKTLRNSDLKP 592
G F H + ++ Y I+ + + G L + L P
Sbjct 60 AEQGLFALHWQAHQHCYAIGIE-INLWLQHGLDVL----VNGSRAYLPEAQRRYRHQLLP 114
Query 593 YIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGH 637
+ ++P L L + G+ + + +Q H
Sbjct 115 LCLTVSP---AILAQRLRQRGRENSEQIDARLQRAQHYQQQLPSH 156
>sp|P87379|GRB2A_XENLA Growth factor receptor-bound protein 2-A
OS=Xenopus laevis OX=8355 GN=grb2-a PE=1 SV=2
Length=229
Score = 69.3 bits (168), Expect = 6e-12, Method: Composition-based stats.
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 7/63 (11%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+V+A FD+DP +D L F++GD + V+ DPNWW+ P + P
Sbjct 172 YVQALFDFDPQEDGE-------LGFRRGDFIQVVDNSDPNWWKGTCLSQTGMFPRNYVTP 224
Query 409 GKS 411
Sbjct 225 VNR 227
Score = 40.4 bits (93), Expect = 0.027, Method: Composition-based stats.
Identities = 18/63 (29%), Positives = 32/63 (51%), Gaps = 14/63 (22%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE-DPNWWQAYREGDEDNQPLAGLVPGK 410
A +D+ + D LSF++GD+L V+++E D NW++A G + G +P
Sbjct 5 AKYDFKATADDE-------LSFKRGDVLKVLNEECDQNWYKAELNGKD------GFIPKN 51
Query 411 SFQ 413
+
Sbjct 52 YIE 54
>sp|Q13424|SNTA1_HUMAN Alpha-1-syntrophin OS=Homo sapiens OX=9606
GN=SNTA1 PE=1 SV=1
Length=505
Score = 71.6 bits (174), Expect = 9e-12, Method: Composition-based stats.
Identities = 22/105 (21%), Positives = 44/105 (42%), Gaps = 3/105 (3%)
Query 239 DERVYESIGQYGGETVKIVRIEKARDIPLGATV---RNEMDSVIISRIVKGGAAEKSGLL 295
+ + + V + KA LG ++ R ++IS+I KG AA+++ L
Sbjct 70 PGAGPPQLPEALLLQRRRVTVRKADAGGLGISIKGGRENKMPILISKIFKGLAADQTEAL 129
Query 296 HEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
GD +L +NG ++ +E +L + + + + P
Sbjct 130 FVGDAILSVNGEDLSSATHDEAVQVLKKTGKEVVLEVKYMKDVSP 174
>sp|Q8NI35|INADL_HUMAN InaD-like protein OS=Homo sapiens OX=9606
GN=PATJ PE=1 SV=3
Length=1801
Score = 72.4 bits (176), Expect = 1e-11, Method: Composition-based stats.
Identities = 36/136 (26%), Positives = 59/136 (43%), Gaps = 17/136 (13%)
Query 197 LKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKI 256
L+ H+E +TAL TP L++ D E + E++ + + K
Sbjct 1493 LRNSSHEEA--ITALRQTPQKVRLVVYRD---EAHYR--------DEENLEIFPVDLQK- 1538
Query 257 VRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
+ R + L + V IS IVKGGAA+ G L +GD++L +NG ++R
Sbjct 1539 ---KAGRGLGLSIVGKRNGSGVFISDIVKGGAADLDGRLIQGDQILSVNGEDMRNASQET 1595
Query 317 VFDLLSDMHGTLTFVL 332
V +L G + +
Sbjct 1596 VATILKCAQGLVQLEI 1611
Score = 69.7 bits (169), Expect = 7e-11, Method: Composition-based stats.
Identities = 22/98 (22%), Positives = 44/98 (45%), Gaps = 4/98 (4%)
Query 238 TDERVYESIGQYGGETVKIVRIEKAR-DIPLGATVRNE--MDSVIISRIVKGGAAEKSGL 294
+ G+ + I+ I K R + L + +++++I + + GAA + G
Sbjct 1420 PLSVDPATCPIVPGQEM-IIEISKGRSGLGLSIVGGKDTPLNAIVIHEVYEEGAAARDGR 1478
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
L GD++LE+NG+++R E L + V+
Sbjct 1479 LWAGDQILEVNGVDLRNSSHEEAITALRQTPQKVRLVV 1516
Score = 68.9 bits (167), Expect = 1e-10, Method: Composition-based stats.
Identities = 31/147 (21%), Positives = 64/147 (44%), Gaps = 7/147 (5%)
Query 187 QDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESI 246
Q LA + + + H++ L T L++A + V + + D + E++
Sbjct 184 QILAINHTPLDQNISHQQAIALLQ--QTTGSLRLIVAREPVHTKSSTSSSLNDTTLPETV 241
Query 247 GQYGGETVKIVRIEKARDIPLGATV-RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
E V+++ LG + + V++ IV GG A++ G L GD +L+I
Sbjct 242 CWGHVEEVELI----NDGSGLGFGIVGGKTSGVVVRTIVPGGLADRDGRLQTGDHILKIG 297
Query 306 GIEIRGKDVNEVFDLLSDMHGTLTFVL 332
G ++G +V +L + ++ ++
Sbjct 298 GTNVQGMTSEQVAQVLRNCGNSVRMLV 324
Score = 67.4 bits (163), Expect = 3e-10, Method: Composition-based stats.
Identities = 20/125 (16%), Positives = 51/125 (41%), Gaps = 12/125 (10%)
Query 228 AEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV------------RNEM 275
A +L + E+ +IV I + ++ LG ++ E+
Sbjct 1040 ATDTCELPEREEGEGEETPNFSHWGPPRIVEIFREPNVSLGISIVGGQTVIKRLKNGEEL 1099
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ I ++++ A K+ L GD++LE++G++++ +E + + + + F++
Sbjct 1100 KGIFIKQVLEDSPAGKTNALKTGDKILEVSGVDLQNASHSEAVEAIKNAGNPVVFIVQSL 1159
Query 336 QQIKP 340
Sbjct 1160 SSTPR 1164
Score = 62.4 bits (150), Expect = 1e-08, Method: Composition-based stats.
Identities = 29/117 (25%), Positives = 46/117 (39%), Gaps = 12/117 (10%)
Query 233 QLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKS 292
+EP T E E G + I R PLG V I+ I G A ++
Sbjct 1671 DMEPRTVEINRELSDALG------ISIAGGRGSPLG------DIPVFIAMIQASGVAART 1718
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIH 349
L GD ++ ING + G +V +LL + +G + ++ I A+ +
Sbjct 1719 QKLKVGDRIVSINGQPLDGLSHADVVNLLKNAYGRIILQVVADTNISAIAAQLENMS 1775
Score = 59.7 bits (143), Expect = 9e-08, Method: Composition-based stats.
Identities = 40/168 (24%), Positives = 64/168 (38%), Gaps = 15/168 (9%)
Query 174 NKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQ 233
PP ++ A + V +E +E L +IQAL E +
Sbjct 472 EPLKPPALFLTGAVETETNV-----DGEDEEIKERIDTLKNDNIQALEKLEKVPDSPENE 526
Query 234 LEP-------ITDERVYESIGQYGGETVKIVRIEKARDIP---LGATVRNEMDSVIISRI 283
L+ E + ++ + ++ + K I LG V + IS I
Sbjct 527 LKSRWENLLGPDYEVMVATLDTQIADDAELQKYSKLLPIHTLRLGVEVDSFDGHHYISSI 586
Query 284 VKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV 331
V GG + GLL DE+LE+NG+++ GK E L ++ T V
Sbjct 587 VSGGPVDTLGLLQPEDELLEVNGMQLYGKSRREAVSFLKEVPPPFTLV 634
Score = 57.8 bits (138), Expect = 3e-07, Method: Composition-based stats.
Identities = 25/104 (24%), Positives = 46/104 (44%), Gaps = 6/104 (6%)
Query 238 TDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD----SVIISRIVKGGAAEKSG 293
TD+++ + GE I+ +EK ++ LG ++ D S+ + I G A G
Sbjct 1222 TDQKIRQRYADLPGELH-IIELEKDKN-GLGLSLAGNKDRSRMSIFVVGINPEGPAAADG 1279
Query 294 LLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
+ GDE+LEIN + G+ ++ + V I ++
Sbjct 1280 RMRIGDELLEINNQILYGRSHQNASAIIKTAPSKVKLVFIRNED 1323
Score = 55.4 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 34/223 (15%), Positives = 78/223 (35%), Gaps = 21/223 (9%)
Query 122 LEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFP 181
L++ + LK D+ E +S+ + +++ F + +I + +
Sbjct 10 LQVLQVLDRLKMKLQEKGDTSQNEKLSMFYETLKSPLFNQILTLQQSIKQLKGQLNHIPS 69
Query 182 LISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDER 241
S D +++ V G ++ P +++ P
Sbjct 70 DCSANFDFSRKGLLVFTDGSITNGN-----VHRP-------SNNSTVSGLFPWTPKLGNE 117
Query 242 VYESIGQYGGETVKI--VRIEKARDIPLG---ATVRNEMDS---VIISRIVKGGAAEKSG 293
+ S+ Q + +I + IE+ LG +R++ + + + G A++
Sbjct 118 DFNSVIQQMAQGRQIEYIDIERPSTGGLGFSVVALRSQNLGKVDIFVKDVQPGSVADRDQ 177
Query 294 LLHEGDEVLEINGIEI-RGKDVNEVFDLLSDMHGTLTFVLIPS 335
L E D++L IN + + + LL G+L ++
Sbjct 178 RLKENDQILAINHTPLDQNISHQQAIALLQQTTGSLRLIVARE 220
Score = 55.1 bits (131), Expect = 2e-06, Method: Composition-based stats.
Identities = 25/135 (19%), Positives = 59/135 (44%), Gaps = 23/135 (17%)
Query 226 KVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVR------NEMDSVI 279
VA + P +D ++E+ V++VR + + + + E +
Sbjct 348 TVASKG----PGSDSSLFETYN------VELVR-KDGQSLGIRIVGYVGTSHTGEASGIY 396
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS---- 335
+ I+ G AA +G + D+++ ++G+ I+G ++V ++L + + L+
Sbjct 397 VKSIIPGSAAYHNGHIQVNDKIVAVDGVNIQGFANHDVVEVLRNAGQVVHLTLVRRKTSS 456
Query 336 --QQIKPPPAKETVI 348
++PP + TV+
Sbjct 457 STSPLEPPSDRGTVV 471
Score = 52.4 bits (124), Expect = 1e-05, Method: Composition-based stats.
Identities = 23/100 (23%), Positives = 41/100 (41%), Gaps = 8/100 (8%)
Query 237 ITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDS-------VIISRIVKGGAA 289
+ E + VKIV + K LG ++ + D ++I +V G A
Sbjct 667 VNTEEDDDGELALWSPEVKIVELVK-DCKGLGFSILDYQDPLDPTRSVIVIRSLVADGVA 725
Query 290 EKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLT 329
E+SG L GD ++ +N + + E ++L + L
Sbjct 726 ERSGGLLPGDRLVSVNEYCLDNTSLAEAVEILKAVPPGLV 765
>sp|B2AIF3|RBKTP_CUPTR Bifunctional ribose 1,5-bisphosphokinase-thymidine
phosphorylase OS=Cupriavidus taiwanensis (strain
DSM 17343 / BCRC 17206 / CCUG 44338 / CIP 107171 / LMG 19424
/ R1) OX=977880 GN=phnN PE=3 SV=1
Length=601
Score = 71.6 bits (174), Expect = 1e-11, Method: Composition-based stats.
Identities = 26/154 (17%), Positives = 52/154 (34%), Gaps = 13/154 (8%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++GP G++ L D + A TR + V G + VS F
Sbjct 8 FFVVGPSGAGKDALMDGARAALDDNYVFARRVITRP--EGAV-GEAHEAVSEAEFARRQR 64
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKT----LRNSDLKPYIIFI 597
+G+F+ + YG S+ + G+ + + L + ++ +
Sbjct 65 SGEFLVTWDAHDLRYGLP-CSLMSELERGRHVVA----NGSRAVIAELAQRLPRFVVVLV 119
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREM 631
P Q+ L +A G+ + R + +
Sbjct 120 TAP-QDVLARRIAARGRESGEQIARRVARTGAAL 152
>sp|Q64512|PTN13_MOUSE Tyrosine-protein phosphatase non-receptor
type 13 OS=Mus musculus OX=10090 GN=Ptpn13 PE=1 SV=2
Length=2453
Score = 72.4 bits (176), Expect = 1e-11, Method: Composition-based stats.
Identities = 26/109 (24%), Positives = 44/109 (40%), Gaps = 9/109 (8%)
Query 245 SIGQYGGETVKIVRIEKARDIPLGATV------RNEMDSVIISRIVKGGAAEKSGLLHEG 298
SI + +V ++K LG + V IS + GG A+ G L G
Sbjct 1073 SIVSSPEREITLVNLKKDPKHGLGFQIIGGEKMGRLDLGVFISAVTPGGPADLDGCLKPG 1132
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV 347
D ++ +N + + G + D+L + +T V+ Q K P+K
Sbjct 1133 DRLISVNSVSLEGVSHHAAVDILQNAPEDVTLVI---SQPKEKPSKVPS 1178
Score = 69.3 bits (168), Expect = 1e-10, Method: Composition-based stats.
Identities = 21/105 (20%), Positives = 46/105 (44%), Gaps = 8/105 (8%)
Query 250 GGETVKIVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
G+T ++ + + + T + + I+ GAAE G +H+GD VL +N
Sbjct 1352 PGDTFEVELAKTDGSLGISVTGGVNTSVRHGGIYVKAIIPKGAAESDGRIHKGDRVLAVN 1411
Query 306 GIEIRGKDVNEVFDLLSDMHGTLTFVL----IPSQQIKPPPAKET 346
G+ + G + + L + + +L +P+ + + P ++
Sbjct 1412 GVSLEGATHKQAVETLRNTGQVVHLLLEKGQVPTSRERDPAGPQS 1456
Score = 57.0 bits (136), Expect = 6e-07, Method: Composition-based stats.
Identities = 16/79 (20%), Positives = 36/79 (46%), Gaps = 3/79 (4%)
Query 256 IVRIEKARDIPLGATV--RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
++ + K+ LG TV ++ + +++ A+ G L GD ++++N ++
Sbjct 1764 LITLVKSEKGSLGFTVTKGSQSIGCYVHDVIQD-PAKGDGRLKAGDRLIKVNDTDVTNMT 1822
Query 314 VNEVFDLLSDMHGTLTFVL 332
+ +LL T+ VL
Sbjct 1823 HTDAVNLLRAAPKTVRLVL 1841
Score = 51.6 bits (122), Expect = 3e-05, Method: Composition-based stats.
Identities = 30/164 (18%), Positives = 59/164 (36%), Gaps = 31/164 (19%)
Query 197 LKPVHHKEGQE-LTALLNTPHIQALLLAHDKVAEQE-----MQLEPITDERVYESIGQYG 250
L+ HK+ E L H+ LL +E Q P + ++ +
Sbjct 1415 LEGATHKQAVETLRNTGQVVHL--LLEKGQVPTSRERDPAGPQSPPPDQDAQRQAPEKVA 1472
Query 251 GETVKI-------------VRIEKARDIPLGATVRNEMDSV---------IISRIVKGGA 288
+T + V++ K LG + E + + + ++ G
Sbjct 1473 KQTPHVKDYSFVTEDNTFEVKLFKNSS-GLGFSFSREDNLIPEQINGSIVRVKKLFPGQP 1531
Query 289 AEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
A +SG + GD +L++NG ++G +V L ++ +L
Sbjct 1532 AAESGKIDVGDVILKVNGAPLKGLSQQDVISALRGTAPEVSLLL 1575
Score = 46.6 bits (109), Expect = 9e-04, Method: Composition-based stats.
Identities = 41/234 (18%), Positives = 75/234 (32%), Gaps = 28/234 (12%)
Query 132 KHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAIT-VHMNKASPPFPLISNAQDLA 190
KH H +E+I+ L + N + ++ IT V K S F + +Q +
Sbjct 1728 KHFTHLASQLSKEENITTLKNDLGNHLEDSELEVELLITLVKSEKGSLGFTVTKGSQSIG 1787
Query 191 QEVQTVLKPVHHKEGQELT--ALLNTPHIQALLLAH-DKV-----AEQEMQL-------- 234
V V++ +G+ L+ + H D V A + ++L
Sbjct 1788 CYVHDVIQDPAKGDGRLKAGDRLIKVNDTDVTNMTHTDAVNLLRAAPKTVRLVLGRILEL 1847
Query 235 --EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKS 292
P+ + + GE + L + V IS I AA
Sbjct 1848 PRMPVFPHLLPDITVTCHGEEL---------GFSLSGGQGSPHGVVYISDINPRSAAAVD 1898
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKET 346
G L D + +NG+ +G + + L ++ + P +
Sbjct 1899 GSLQLLDIIHYVNGVSTQGMTLEDANRALDLSLPSVVLKVTRDGCPVVPTTRAA 1952
>sp|Q5RD32|GOPC_PONAB Golgi-associated PDZ and coiled-coil motif-containing
protein OS=Pongo abelii OX=9601 GN=GOPC PE=2 SV=1
Length=462
Score = 70.9 bits (172), Expect = 1e-11, Method: Composition-based stats.
Identities = 23/104 (22%), Positives = 44/104 (42%), Gaps = 3/104 (3%)
Query 234 LEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAE 290
++ G ++ V + K LG ++ + ++IS I G A+
Sbjct 266 MQAPPGHDQDSLKKSQGVGPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPAD 325
Query 291 KSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP 334
+ G LH GD +L ++G+ +R E +LS G + F ++
Sbjct 326 RCGGLHVGDAILAVDGVNLRDTKHKEAVTVLSQQRGEIEFEVVY 369
>sp|Q9WVJ4|SYJ2B_RAT Synaptojanin-2-binding protein OS=Rattus
norvegicus OX=10116 GN=Synj2bp PE=1 SV=2
Length=145
Score = 66.2 bits (160), Expect = 1e-11, Method: Composition-based stats.
Identities = 17/89 (19%), Positives = 36/89 (40%), Gaps = 6/89 (7%)
Query 260 EKARDIPLGATVRNEMD------SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
+ + + +SRI + GAA + G L EGD++L +NG +++
Sbjct 18 RGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKEDGAAARDGRLQEGDKILSVNGQDLKNLL 77
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPP 342
+ DL + ++ + ++ P
Sbjct 78 HQDAVDLFRNAGYAVSLRVQHRLPVQNGP 106
>sp|Q3T0C9|SYJ2B_BOVIN Synaptojanin-2-binding protein OS=Bos taurus
OX=9913 GN=SYNJ2BP PE=2 SV=1
Length=145
Score = 65.8 bits (159), Expect = 2e-11, Method: Composition-based stats.
Identities = 18/89 (20%), Positives = 36/89 (40%), Gaps = 6/89 (7%)
Query 260 EKARDIPLGATVRNEMD------SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
+ + + +SRI + GAA G L EGD++L +NG +++
Sbjct 18 RGPSGLGFNIVGGTDQQYVSNDSGIFVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLL 77
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPP 342
+ DL + ++ + Q++ P
Sbjct 78 HQDAVDLFRNAGYAVSLRVQHRLQVQNGP 106
>sp|Q14160|SCRIB_HUMAN Protein scribble homolog OS=Homo sapiens
OX=9606 GN=SCRIB PE=1 SV=5
Length=1630
Score = 71.6 bits (174), Expect = 2e-11, Method: Composition-based stats.
Identities = 26/110 (24%), Positives = 45/110 (41%), Gaps = 16/110 (15%)
Query 232 MQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---------SVIISR 282
++L + E G + V + LG ++ + +SR
Sbjct 844 LRLPLLPPESP-------GPLRQRHVACLARSERGLGFSIAGGKGSTPYRAGDAGIFVSR 896
Query 283 IVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
I +GGAA ++G L GD VL ING+++ + LL+ T+ +L
Sbjct 897 IAEGGAAHRAGTLQVGDRVLSINGVDVTEARHDHAVSLLTAASPTIALLL 946
Score = 65.5 bits (158), Expect = 1e-09, Method: Composition-based stats.
Identities = 21/123 (17%), Positives = 54/123 (44%), Gaps = 9/123 (7%)
Query 245 SIGQYGGETVKIVRIEKARDIPLGATVR-------NEMDSVIISRIVKGGAAEKSGLLHE 297
+ E + + + + + + + + + ISR+ + G A ++G +
Sbjct 718 EPARIEEEELTLTILRQTGGLGISIAGGKGSTPYKGDDEGIFISRVSEEGPAARAG-VRV 776
Query 298 GDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYD 357
GD++LE+NG+ ++G + +E + L + + + ++P T+ ++ DY
Sbjct 777 GDKLLEVNGVALQGAEHHEAVEALRGAGTAVQMRVWRERMVEPE-NAVTITPLRPEDDYS 835
Query 358 PSD 360
P +
Sbjct 836 PRE 838
Score = 63.2 bits (152), Expect = 7e-09, Method: Composition-based stats.
Identities = 27/110 (25%), Positives = 46/110 (42%), Gaps = 18/110 (16%)
Query 247 GQYGGETVKIVRIEKARDIPLGATV-----------RNEMDSVIISRIVKGGAAEKSGLL 295
G Y E +++ R PLG ++ + V IS+++ G A +SG L
Sbjct 998 GPYPVEEIRLPR----AGGPLGLSIVGGSDHSSHPFGVQEPGVFISKVLPRGLAARSG-L 1052
Query 296 HEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKE 345
GD +L +NG ++R E L L+ ++ + PP +E
Sbjct 1053 RVGDRILAVNGQDVRDATHQEAVSALLRPCLELSLLVR--RDPAPPGLRE 1100
Score = 62.8 bits (151), Expect = 8e-09, Method: Composition-based stats.
Identities = 24/95 (25%), Positives = 41/95 (43%), Gaps = 12/95 (13%)
Query 250 GGETVKIVRIEKARDIPLGATVRN------------EMDSVIISRIVKGGAAEKSGLLHE 297
++ + I+KA LG ++R + + IS++ GAA + G L
Sbjct 1094 APPGLRELCIQKAPGERLGISIRGGARGHAGNPRDPTDEGIFISKVSPTGAAGRDGRLRV 1153
Query 298 GDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
G +LE+N + G E LL + TLT ++
Sbjct 1154 GLRLLEVNQQSLLGLTHGEAVQLLRSVGDTLTVLV 1188
>sp|E2QYC9|INADL_CANLF InaD-like protein OS=Canis lupus familiaris
OX=9615 GN=PATJ PE=1 SV=3
Length=1828
Score = 71.6 bits (174), Expect = 2e-11, Method: Composition-based stats.
Identities = 37/183 (20%), Positives = 76/183 (42%), Gaps = 11/183 (6%)
Query 187 QDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESI 246
Q LA + + + H++ L T L++A + V + +TD + E++
Sbjct 184 QILAINHTPLDQNISHQQAIALLQ--QTTGSLHLVVAREPVHTKSRTSINLTDTTMPETV 241
Query 247 GQYGGETVKIVRIEKARDIPLGATV-RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
E V+++ LG + + V++ IV GG A++ G L GD +L+I
Sbjct 242 HWGHIEDVELI----NDGSGLGFGIVGGKSSGVVVRTIVPGGLADRDGRLQTGDHILKIG 297
Query 306 GIEIRGKDVNEVFDLLSDMHGTLTFVLIP----SQQIKPPPAKETVIHVKAHFDYDPSDD 361
+++G +V +L + ++ ++ + PP + + A + PS D
Sbjct 298 DTDVQGMTSEQVAQVLRNCGNSVRMLVARDPVGETSVTPPTPAALPVALPAVANRSPSTD 357
Query 362 PYV 364
+
Sbjct 358 SSL 360
Score = 69.7 bits (169), Expect = 6e-11, Method: Composition-based stats.
Identities = 60/318 (19%), Positives = 120/318 (38%), Gaps = 39/318 (12%)
Query 42 DLGTRMMPIRRSAQLERIRQQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDN 101
++G + +P S++LE I Q + + G+++ LD + ++Q+ P+
Sbjct 1363 EVGIKQLPENESSKLEDISQ----VAGQGMVAGQQKALDCPTD---NAVSQMKPQKYSTK 1415
Query 102 PMFDTEEGIVLESPHYAV------------KILEIEDLFSSLKHIQHTLVDSQSQEDISL 149
F ++E + +P Y L ++ + Q +++
Sbjct 1416 VSFSSQEIPLAPAPSYHSTDVDFTSYGGFQAPLSVDPATCPIVPGQEMIIEISKGRSGLG 1475
Query 150 LLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELT 209
L + +A IH V+ A+ + + + L+ H+E +T
Sbjct 1476 LSIVGGRDTPLDAIVIHE---VYEEGAAARDGRLWAGDQILEVNGIDLRSASHEEA--IT 1530
Query 210 ALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGA 269
AL TP L++ D E + E++ + + K + R + L
Sbjct 1531 ALRQTPQKVRLVVYRD---EAHYR--------DEENLEIFPVDLQK----KAGRGLGLSI 1575
Query 270 TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLT 329
+ V IS IVKGGAA+ L +GD++L +NG ++R V +L G +
Sbjct 1576 VGKRNGSGVFISDIVKGGAADLDRRLIQGDQILSVNGEDMRNASQETVATVLKCAQGLVQ 1635
Query 330 FVLIPSQQIKPPPAKETV 347
+ + +++T
Sbjct 1636 LEIGRLRAGSWTSSRKTS 1653
Score = 67.4 bits (163), Expect = 4e-10, Method: Composition-based stats.
Identities = 27/167 (16%), Positives = 62/167 (37%), Gaps = 19/167 (11%)
Query 193 VQTVLKPVHHKEGQELTALLNTPHIQAL--LLAHDKVAEQEM-----QLEPITDERVYES 245
+ L V + QE L P + + A+ + +L + E+
Sbjct 1000 MLVELPAVAQRREQEDLPLYQLPRTRVVSKASAYTGASSSRYTAGACELPEREEGEGEET 1059
Query 246 IGQYGGETVKIVRIEKARDIPLGATV------------RNEMDSVIISRIVKGGAAEKSG 293
+IV I + ++ LG ++ E+ + I ++++ A K+
Sbjct 1060 PNFSHWGPPRIVEIFREPNVSLGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTN 1119
Query 294 LLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
L GD++LE++G++++ E + + + + FV+
Sbjct 1120 ALKTGDKILEVSGVDLQNASHREAVEAIKNAGNPVVFVVQSLSSTPR 1166
Score = 63.2 bits (152), Expect = 7e-09, Method: Composition-based stats.
Identities = 30/150 (20%), Positives = 53/150 (35%), Gaps = 17/150 (11%)
Query 226 KVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVK 285
+ M + P T E + E G + I + PLG + I+ I
Sbjct 1691 SLKSSGMDMGPRTVEIIRELSDALG------ISIAGGKGSPLG------DIPIFIAMIQA 1738
Query 286 GGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKE 345
G A ++ L GD ++ ING + G +V +LL + +G + ++ I +
Sbjct 1739 SGVAARTQKLKVGDRIVSINGQPLDGLSHADVVNLLKNAYGRIILQVVADTNISAIATQL 1798
Query 346 TVIHVKAH-----FDYDPSDDPYVPCRELG 370
+ H ++ P D G
Sbjct 1799 ENMSTGYHLGSPTAEHHPEDTEEPLQMTAG 1828
Score = 58.9 bits (141), Expect = 2e-07, Method: Composition-based stats.
Identities = 39/227 (17%), Positives = 78/227 (34%), Gaps = 21/227 (9%)
Query 118 AVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKAS 177
A L++ + LK D+ E +SL + +Q+ F + +I + S
Sbjct 6 APDKLQVLQVLDRLKMKLQEKGDTSQNEKLSLFYETLQSPLFNQILTLQQSIKQLKGQLS 65
Query 178 PPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPI 237
S D +++ V G P +++ P
Sbjct 66 HIPSDCSTNFDFSRKGLLVFTDSAITNGNA-----QRP-------SNNLTVSGLFPWTPK 113
Query 238 TDERVYESIGQYGGETVKI--VRIEKARDIPLG---ATVRNEMDS---VIISRIVKGGAA 289
+ + S+ Q + +I + IE+ LG +R++ + + + G A
Sbjct 114 SGNEDFNSVIQQMAQGRQIEYIDIERPSTGGLGFSVVALRSQNLGEVDIFVKEVQPGSIA 173
Query 290 EKSGLLHEGDEVLEINGIEI-RGKDVNEVFDLLSDMHGTLTFVLIPS 335
++ L E D++L IN + + + LL G+L V+
Sbjct 174 DRDQRLRENDQILAINHTPLDQNISHQQAIALLQQTTGSLHLVVARE 220
Score = 57.8 bits (138), Expect = 3e-07, Method: Composition-based stats.
Identities = 24/133 (18%), Positives = 51/133 (38%), Gaps = 19/133 (14%)
Query 220 LLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKI---------VRIEKARDIPLGAT 270
+L+A D V E + P T + ++ + V + K LG
Sbjct 322 MLVARDPVGETS--VTPPTPAALPVALPAVANRSPSTDSSLYETYGVELIKKDGQSLGIR 379
Query 271 V--------RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
+ E + + I+ G AA +G + D+++ ++G+ I+G +V ++L
Sbjct 380 IVGYIGTAHTGEASGIYVKSIIPGSAAYHNGQIQVNDKIVAVDGVNIQGFTNQDVVEVLR 439
Query 323 DMHGTLTFVLIPS 335
+ + L+
Sbjct 440 NAGQVVHLTLVRR 452
Score = 56.2 bits (134), Expect = 1e-06, Method: Composition-based stats.
Identities = 31/144 (22%), Positives = 56/144 (39%), Gaps = 8/144 (6%)
Query 191 QEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYG 250
+E + + + + Q L L P +++ + L E + ++
Sbjct 496 EETEERMDNLKNDNIQALEKLERVPD-----SPENELKSRWENLLGPDYEVMVATLDTQI 550
Query 251 GETVKIVRIEKARDIP---LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
+ ++ + K I LG V + IS I GG + LL DE+LE+NG+
Sbjct 551 ADDAELQKYSKLLPIHTLRLGMEVDSFDGHHYISSIAPGGPVDALNLLQPEDELLEVNGV 610
Query 308 EIRGKDVNEVFDLLSDMHGTLTFV 331
++ GK E L ++ T V
Sbjct 611 QLYGKSRREAVSFLKEVPPPFTLV 634
Score = 55.1 bits (131), Expect = 2e-06, Method: Composition-based stats.
Identities = 23/95 (24%), Positives = 40/95 (42%), Gaps = 6/95 (6%)
Query 247 GQYGGETVKIVRIEKARDIPLGATVRNEMD----SVIISRIVKGGAAEKSGLLHEGDEVL 302
GE I+ +EK ++ LG ++ D S+ + I G A G + GDE+L
Sbjct 1233 ADLPGELH-IIELEKDKN-GLGLSLAGNKDRSRMSIFVVGINPEGPAATDGRMRIGDELL 1290
Query 303 EINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
EIN + G+ ++ + V I ++
Sbjct 1291 EINNQILYGRSHQNASAVIKTAPSKVKLVFIRNED 1325
Score = 47.0 bits (110), Expect = 6e-04, Method: Composition-based stats.
Identities = 21/85 (25%), Positives = 37/85 (44%), Gaps = 8/85 (9%)
Query 252 ETVKIVRIEKARDIPLGATVRNEMDS-------VIISRIVKGGAAEKSGLLHEGDEVLEI 304
VKIV + K LG ++ + D ++I +V G AEK G L GD ++ +
Sbjct 682 PEVKIVELVK-DHKGLGFSILDYQDPLDPTRSVIVIRSLVANGVAEKGGELLPGDRLVSV 740
Query 305 NGIEIRGKDVNEVFDLLSDMHGTLT 329
N + + E ++L + +
Sbjct 741 NEYCLENTTLAEAVEVLKAVPPGIV 765
>sp|A8IA58|RBKTP_AZOC5 Bifunctional ribose 1,5-bisphosphokinase-thymidine
phosphorylase OS=Azorhizobium caulinodans (strain
ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845
/ NCIMB 13405 / ORS 571) OX=438753 GN=phnN PE=3 SV=1
Length=693
Score = 71.2 bits (173), Expect = 2e-11, Method: Composition-based stats.
Identities = 27/151 (18%), Positives = 52/151 (34%), Gaps = 7/151 (5%)
Query 479 KRPIILIGPQNCGQNELRQ--RLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
++GP G++ L + + R+ A TR G + +S F
Sbjct 7 GLFFFVVGPSGSGKDTLIEGAKAALGPTGRYVFARRAITRPADAG---GEAHEALSVDQF 63
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
+A +A G F+ H E YG ++ + +G+ + + + L ++
Sbjct 64 DAVLAQGGFLIHWEAHGLKYG-LRATLLDDMAAGRHVIANGSRAMVAALAERVPHLVVVE 122
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEK 627
I P + L L G+ + K
Sbjct 123 ITAP-EAVLAERLKGRGREGAENIAARLERK 152
>sp|Q46UT0|RBKTP_CUPPJ Bifunctional ribose 1,5-bisphosphokinase-thymidine
phosphorylase OS=Cupriavidus pinatubonensis (strain
JMP 134 / LMG 1197) OX=264198 GN=phnN PE=3 SV=2
Length=602
Score = 70.9 bits (172), Expect = 2e-11, Method: Composition-based stats.
Identities = 25/152 (16%), Positives = 52/152 (34%), Gaps = 14/152 (9%)
Query 482 IILIGPQNCGQNELRQ-RLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
+++GP G++ L D + A TR G D+ V+ F
Sbjct 8 FLVVGPSGAGKDSLIDGARATLGNDEYVFARRIITR---PSGSPGEDHESVAEAEFAERE 64
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK----TLRNSDLKPYIIF 596
G+F+ YG + ++ +GK + + L + ++
Sbjct 65 RNGEFLVTWHAHGLRYGLP-QWLVGLLETGKHVVA----NGSRGVIAMLARQLPRFVVVN 119
Query 597 IAPPSQERLRALLAKEGKNPKPEELREIIEKT 628
+ P Q+ L +A G+ + +R + +
Sbjct 120 VTAP-QDVLAQRIAARGRESGDDVMRRVARQA 150
>sp|Q9D6K5|SYJ2B_MOUSE Synaptojanin-2-binding protein OS=Mus musculus
OX=10090 GN=Synj2bp PE=1 SV=1
Length=145
Score = 65.8 bits (159), Expect = 2e-11, Method: Composition-based stats.
Identities = 17/89 (19%), Positives = 36/89 (40%), Gaps = 6/89 (7%)
Query 260 EKARDIPLGATVRNEMD------SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
+ + + +SRI + GAA + G L EGD++L +NG +++
Sbjct 18 RGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKEDGAAAQDGRLQEGDKILSVNGQDLKNLL 77
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPP 342
+ DL + ++ + ++ P
Sbjct 78 HQDAVDLFRNAGCAVSLRVQHRLPVQNGP 106
>sp|Q5ZIK2|PDZ11_CHICK PDZ domain-containing protein 11 OS=Gallus
gallus OX=9031 GN=PDZD11 PE=2 SV=1
Length=140
Score = 65.5 bits (158), Expect = 2e-11, Method: Composition-based stats.
Identities = 25/121 (21%), Positives = 50/121 (41%), Gaps = 10/121 (8%)
Query 232 MQLEP---ITDERVY--ESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISRI 283
+ P ERVY + + + V ++K LG +R + IS++
Sbjct 18 YESPPAWVPPHERVYHPDYNNELTQFLPRTVVLKKPPGAQLGFNIRGGKASQLGIFISKV 77
Query 284 VKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG-TLTFVLIPSQQIKPPP 342
+ A ++G L EGD+VL +N ++ + + ++ ++L T+ P + P
Sbjct 78 IPDSDAHRAG-LQEGDQVLSVNDVDFQDIEHSKAVEILKTAREITMRVRYFPYSKCLLAP 136
Query 343 A 343
Sbjct 137 N 137
>sp|A6TH13|PHNN_KLEP7 Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721
/ MGH 78578) OX=272620 GN=phnN PE=3 SV=1
Length=187
Score = 67.0 bits (162), Expect = 2e-11, Method: Composition-based stats.
Identities = 27/158 (17%), Positives = 51/158 (32%), Gaps = 18/158 (11%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
+ I L+GP G++ L L +E + A + TR + +S F
Sbjct 3 GKLIWLVGPSGSGKDSLLAALRQREHPQLLVAHRYITRPFNAGSEN---HIALSEHEFFT 59
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS-------LKTLRNSDLK 591
F YG ++ + +++G + + L
Sbjct 60 RAEQHLFALSWHANNTYYGIGVE-IDLWLHAGFDVVA----NGSRAHLALARERYGEVLV 114
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTR 629
P + ++PP LR L + G+ E + + R
Sbjct 115 PICLAVSPP---VLRQRLEQRGRENALEIAQRLDRAAR 149
>sp|P57105|SYJ2B_HUMAN Synaptojanin-2-binding protein OS=Homo
sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2
Length=145
Score = 65.5 bits (158), Expect = 3e-11, Method: Composition-based stats.
Identities = 18/89 (20%), Positives = 36/89 (40%), Gaps = 6/89 (7%)
Query 260 EKARDIPLGATVRNEMD------SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
+ + + +SRI + GAA G L EGD++L +NG +++
Sbjct 18 RGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLL 77
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPP 342
+ DL + ++ + Q++ P
Sbjct 78 HQDAVDLFRNAGYAVSLRVQHRLQVQNGP 106
>sp|Q7NWY0|PHNN_CHRVO Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Chromobacterium violaceum (strain ATCC 12472 / DSM 30191
/ JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757) OX=243365
GN=phnN PE=3 SV=1
Length=185
Score = 66.6 bits (161), Expect = 3e-11, Method: Composition-based stats.
Identities = 30/169 (18%), Positives = 52/169 (31%), Gaps = 21/169 (12%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAG 543
++GP G++ L + A + TR G ++ +SR+ F+A A G
Sbjct 11 VMGPSGAGKDSLLAYARQRLPGGVMFAHRYITRPADAG---GENHVALSREEFDAREAGG 67
Query 544 KFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIF--IAP-- 599
F YG +++ + G + R+S F + P
Sbjct 68 CFALVWRRHGLAYGLGVET-ELWLGQGMDVV----VNGS---RSSLPLAMARFPTLRPLW 119
Query 600 --PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNS 646
S E L L + + R + E +VN
Sbjct 120 ITASPEVLAVRLRQRARECGEVIERRLAEAASFAPPAGCE----VLVND 164
>sp|Q6XJU9|OSTF1_MONAL Osteoclast-stimulating factor 1 OS=Monopterus
albus OX=43700 GN=ostf1 PE=2 SV=1
Length=214
Score = 67.0 bits (162), Expect = 3e-11, Method: Composition-based stats.
Identities = 36/160 (23%), Positives = 59/160 (37%), Gaps = 21/160 (13%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
+A F +DP L F++GDIL++ D NWW+ G GL+P
Sbjct 18 RALFTFDPRTPDE-------LYFEEGDILYISDTSDTNWWKGTCRG------RTGLIPSN 64
Query 411 SFQQQREAMKQTIEEDKEPEKSGKLWCAKKNK-------KKRKKVLYNANKNDDYDNEEI 463
+Q E + + E + L +NK K LY A D E+
Sbjct 65 YVAEQAETIDHPMHEAAKRGNLSWLRECVENKVGINGLDKAGNTALYWACHGGHKDVVEL 124
Query 464 LTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKE 503
L + +Q +L G +++ + L++K
Sbjct 125 LLNQPSVELNQQNKLGDT-VLHAAAWKGYSDIVEMLLDKN 163
>sp|Q8TEW0|PARD3_HUMAN Partitioning defective 3 homolog OS=Homo
sapiens OX=9606 GN=PARD3 PE=1 SV=2
Length=1356
Score = 70.1 bits (170), Expect = 5e-11, Method: Composition-based stats.
Identities = 39/188 (21%), Positives = 73/188 (39%), Gaps = 20/188 (11%)
Query 167 NAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDK 226
+ ++ SP I N + + TV + E H + AH
Sbjct 373 EKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQI----DSHSRLPHSAH-- 426
Query 227 VAEQEMQLEPITDERVYESIGQYGGETVKI-----VRIEKARDIPLGATVR------NEM 275
+ + + V+ + G T KI ++++K + LG ++
Sbjct 427 PSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTE-GLGFSITSRDVTIGGS 485
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS--DMHGTLTFVLI 333
+ + I+ GAA + G L GD ++E+NG+++ GK EV LL M GT++ ++
Sbjct 486 APIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVF 545
Query 334 PSQQIKPP 341
+ P
Sbjct 546 RQEDAFHP 553
Score = 51.6 bits (122), Expect = 2e-05, Method: Composition-based stats.
Identities = 33/160 (21%), Positives = 59/160 (37%), Gaps = 14/160 (9%)
Query 225 DKVAEQEMQLEPI--TDERVYESIGQYGGETVKIVRIEKARDIPLGATV------RNEMD 276
D E ++EP+ D + + VK+V + PLG V
Sbjct 241 DGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVP-NDGGPLGIHVVPFSARGGRTL 299
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGT--LTFVLIP 334
+++ R+ KGG AE L E D ++ IN ++R + + + T + F ++P
Sbjct 300 GLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVP 359
Query 335 S---QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGL 371
+ +Q + E + + F D GL
Sbjct 360 AANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGL 399
Score = 49.7 bits (117), Expect = 1e-04, Method: Composition-based stats.
Identities = 18/75 (24%), Positives = 32/75 (43%), Gaps = 7/75 (9%)
Query 257 VRIEKARDIPLGATVRNEMD-------SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
V + + LG +V+ + + I+ GGAA K G L D+++ +NG +
Sbjct 591 VPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESL 650
Query 310 RGKDVNEVFDLLSDM 324
GK + + L
Sbjct 651 LGKTNQDAMETLRRS 665
>sp|C7LNQ3|PHNN_DESBD Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Desulfomicrobium baculatum (strain DSM 4028 / VKM B-1378
/ X) OX=525897 GN=phnN PE=3 SV=1
Length=187
Score = 65.5 bits (158), Expect = 6e-11, Method: Composition-based stats.
Identities = 32/166 (19%), Positives = 61/166 (37%), Gaps = 12/166 (7%)
Query 480 RPIILIGPQNCGQNELRQ----RLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+ I ++GP G++ L RL + FA R + G ++ +SR
Sbjct 3 KLIYIMGPSGSGKDSLMAEARLRLAAEAPVVFAH-----RYITRPADAGGENHVALSRAE 57
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYII 595
F+ ++ G F E YG + + + SG +++ +L + + +
Sbjct 58 FQLRLSRGLFALSWESHGFAYGIGRE-IDIWMESGLSVVVNGSRGALSAALQAYPELLPV 116
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREII-EKTREMEQNNGHYFD 640
I P + LR L G+ E ++ + +E FD
Sbjct 117 LIDVP-EHILRERLGARGREDAGEIEARLVRARMAVVEAPELVRFD 161
>sp|D4A055|CACB4_RAT Voltage-dependent L-type calcium channel
subunit beta-4 OS=Rattus norvegicus OX=10116 GN=Cacnb4 PE=1
SV=2
Length=519
Score = 68.9 bits (167), Expect = 6e-11, Method: Composition-based stats.
Identities = 71/430 (17%), Positives = 142/430 (33%), Gaps = 64/430 (15%)
Query 239 DERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEK-SGLLHE 297
D S G T + R++ R++ + S I++ G+A+ + +
Sbjct 12 DGPHSPSSQVARGTTTRRSRLK-----------RSDGSTTSTSFILRQGSADSYTSRPSD 60
Query 298 GDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYD 357
D LE + IR + + + Q++ +K VK + Y
Sbjct 61 SDVSLEEDREAIRQEREQQA-----------------AIQLERAKSKPVAFAVKTNVSYC 103
Query 358 PSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ--- 414
+ D VP +SF D LH+ + + +WW G +P +
Sbjct 104 GALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLV---KEGCEIGFIPSPLRLENIR 160
Query 415 -----QREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEM 469
+R G++ + K E I Y+ +
Sbjct 161 IQQEQKRGRFHGGKSSGNSSSSLGEMVSGTF-----RATPTTTAKQKQKVTEHIPPYDVV 215
Query 470 SLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGR 526
RP++L+GP G + +++ L + K RF + T +
Sbjct 216 PSM-------RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRS 268
Query 527 DYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR-TQSLKTL 585
+ S++A + E + I+ + ++ S ++ +L L
Sbjct 269 VLNNPSKRAIIERSNTRSSL--AEVQSE-----IERIFELARSLQLVVLDADTINHPAQL 321
Query 586 RNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVN 645
+ L P I+ + S + L+ L+ GK + + L + ++ Q FD +
Sbjct 322 IKTSLAPIIVHVKVSSPKVLQRLIKSRGK-SQSKHLNVQLVAADKLAQCPPEMFDVILDE 380
Query 646 SDLDKAYQEL 655
+ L+ A + L
Sbjct 381 NQLEDACEHL 390
>sp|Q8R0S4|CACB4_MOUSE Voltage-dependent L-type calcium channel
subunit beta-4 OS=Mus musculus OX=10090 GN=Cacnb4 PE=1 SV=2
Length=519
Score = 68.9 bits (167), Expect = 6e-11, Method: Composition-based stats.
Identities = 71/430 (17%), Positives = 142/430 (33%), Gaps = 64/430 (15%)
Query 239 DERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEK-SGLLHE 297
D S G T + R++ R++ + S I++ G+A+ + +
Sbjct 12 DGPHSPSSQVARGTTTRRSRLK-----------RSDGSTTSTSFILRQGSADSYTSRPSD 60
Query 298 GDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYD 357
D LE + IR + + + Q++ +K VK + Y
Sbjct 61 SDVSLEEDREAIRQEREQQA-----------------AIQLERAKSKPVAFAVKTNVSYC 103
Query 358 PSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ--- 414
+ D VP +SF D LH+ + + +WW G +P +
Sbjct 104 GALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLV---KEGCEIGFIPSPLRLENIR 160
Query 415 -----QREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEM 469
+R G++ + K E I Y+ +
Sbjct 161 IQQEQKRGRFHGGKSSGNSSSSLGEMVSGTF-----RATPTTTAKQKQKVTEHIPPYDVV 215
Query 470 SLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGR 526
RP++L+GP G + +++ L + K RF + T +
Sbjct 216 PSM-------RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRS 268
Query 527 DYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR-TQSLKTL 585
+ S++A + E + I+ + ++ S ++ +L L
Sbjct 269 VLNNPSKRAIIERSNTRSSL--AEVQSE-----IERIFELARSLQLVVLDADTINHPAQL 321
Query 586 RNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVN 645
+ L P I+ + S + L+ L+ GK + + L + ++ Q FD +
Sbjct 322 IKTSLAPIIVHVKVSSPKVLQRLIKSRGK-SQSKHLNVQLVAADKLAQCPPEMFDVILDE 380
Query 646 SDLDKAYQEL 655
+ L+ A + L
Sbjct 381 NQLEDACEHL 390
>sp|O00305|CACB4_HUMAN Voltage-dependent L-type calcium channel
subunit beta-4 OS=Homo sapiens OX=9606 GN=CACNB4 PE=1 SV=2
Length=520
Score = 68.9 bits (167), Expect = 7e-11, Method: Composition-based stats.
Identities = 73/415 (18%), Positives = 142/415 (34%), Gaps = 48/415 (12%)
Query 272 RNEMDSVIISRIVKGGAAEK-SGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTF 330
R++ + S I++ G+A+ + + D LE + IR + +
Sbjct 35 RSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQA------------- 81
Query 331 VLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW 390
+ Q++ +K VK + Y + D VP +SF D LH+ + + +WW
Sbjct 82 ----AIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWW 137
Query 391 QAYREGDEDNQPLAGLVPGKSFQQ----QREAMKQTIEEDKEPEKSGKLWCAKKNKKKRK 446
G +P + Q+E + K S + R
Sbjct 138 IGRLV---KEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRA 194
Query 447 KVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKE 503
A K E I Y+ + RP++L+GP G + +++ L +
Sbjct 195 TPTSTA-KQKQKVTEHIPPYDVVPSM-------RPVVLVGPSLKGYEVTDMMQKALFDFL 246
Query 504 KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSV 563
K RF + T + + S++A + E + I+ +
Sbjct 247 KHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSL--AEVQSE-----IERI 299
Query 564 RQVINSGKICLLSLR-TQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELR 622
++ S ++ +L L + L P I+ + S + L+ L+ GK + + L
Sbjct 300 FELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGK-SQSKHLN 358
Query 623 EIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN---KLDTEPQWVPSTWL 674
+ ++ Q FD + + L+ A + L + + P T L
Sbjct 359 VQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPL 413
>sp|Q24008|INAD_DROME Inactivation-no-after-potential D protein
OS=Drosophila melanogaster OX=7227 GN=inaD PE=1 SV=2
Length=674
Score = 68.9 bits (167), Expect = 7e-11, Method: Composition-based stats.
Identities = 26/127 (20%), Positives = 46/127 (36%), Gaps = 14/127 (11%)
Query 250 GGETVKIVRIEKARDIPLGATV---------RNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
GE + +V ++K G + + + I IV A G L GD
Sbjct 11 AGELIHMVTLDKTGKKSFGICIVRGEVKDSPNTKTTGIFIKGIVPDSPAHLCGRLKVGDR 70
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP-----SQQIKPPPAKETVIHVKAHFD 355
+L +NG ++R V DL+ + + + QQ K P + K F+
Sbjct 71 ILSLNGKDVRNSTEQAVIDLIKEADFKIELEIQTFDKSDEQQAKSDPRSNGYMQAKNKFN 130
Query 356 YDPSDDP 362
+ + +
Sbjct 131 QEQTTNN 137
Score = 46.2 bits (108), Expect = 9e-04, Method: Composition-based stats.
Identities = 14/93 (15%), Positives = 40/93 (43%), Gaps = 5/93 (5%)
Query 250 GGETVKIVRIEKARDIPLGATVRNEMD----SVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
+ ++ + +++ PLG + D + ++ + G A S + GDE++E+N
Sbjct 243 MMKDLRRIEVQRDASKPLGLALAGHKDRQKMACFVAGVDPNG-ALGSVDIKPGDEIVEVN 301
Query 306 GIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
G ++ + + ++ G ++ ++
Sbjct 302 GNVLKNRCHLNASAVFKNVDGDKLVMITSRRKP 334
Score = 45.4 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 17/85 (20%), Positives = 35/85 (41%), Gaps = 4/85 (5%)
Query 252 ETVKIVRIEKARDIPLGATVRNE---MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIE 308
+ V++ K + + + IS + +G AE +G + GD +L +N
Sbjct 362 PKARTVQVRKEGFLGIMVIYGKHAEVGSGIFISDLREGSNAELAG-VKVGDMLLAVNQDV 420
Query 309 IRGKDVNEVFDLLSDMHGTLTFVLI 333
+ ++ LL G +T +L+
Sbjct 421 TLESNYDDATGLLKRAEGVVTMILL 445
Score = 42.4 bits (98), Expect = 0.013, Method: Composition-based stats.
Identities = 15/76 (20%), Positives = 30/76 (39%), Gaps = 0/76 (0%)
Query 257 VRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
V + K LG ++ I+ +++G E L GD + + NG + G
Sbjct 585 VDLMKKAGKELGLSLSPNEIGCTIADLIQGQYPEIDSKLQRGDIITKFNGDALEGLPFQV 644
Query 317 VFDLLSDMHGTLTFVL 332
+ L +G ++ +
Sbjct 645 CYALFKGANGKVSMEV 660
>sp|A4RF61|HSE1_PYRO7 Class E vacuolar protein-sorting machinery
protein HSE1 OS=Pyricularia oryzae (strain 70-15 / ATCC MYA-4617
/ FGSC 8958) OX=242507 GN=HSE1 PE=3 SV=2
Length=718
Score = 68.9 bits (167), Expect = 8e-11, Method: Composition-based stats.
Identities = 46/191 (24%), Positives = 81/191 (42%), Gaps = 35/191 (18%)
Query 333 IPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 392
+P Q TV V+A +D+ PS+D L F+KGD++ V+ +WW+
Sbjct 222 VPLQPTGTGTTAATVSRVRALYDFVPSEDGE-------LEFKKGDVIAVLESVYKDWWRG 274
Query 393 YREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNA 452
+G G+ P ++ + ++ E + +++ KN +K +L +
Sbjct 275 SLKGKT------GIFPLNYVEKLADPTPDELQR--EAQMEAEVFSEIKNVEKLLTLLSTS 326
Query 453 NKNDDYDNEEILTYEEMSLYHQP-ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAV 511
+K++ D+EEI LY Q A R + I LI +++KD F
Sbjct 327 SKDE--DSEEI-----AKLYQQTSAIRPKLIKLI------------EKYSQKKDDFTQLN 367
Query 512 PHTTRSRRDQE 522
++RRD E
Sbjct 368 EKFIKARRDYE 378
>sp|Q6TGW5|OSTF1_DANRE Osteoclast-stimulating factor 1 OS=Danio
rerio OX=7955 GN=ostf1 PE=2 SV=1
Length=214
Score = 65.8 bits (159), Expect = 8e-11, Method: Composition-based stats.
Identities = 38/160 (24%), Positives = 58/160 (36%), Gaps = 21/160 (13%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
+A F +DP L F++GDIL++ D NWW+ G GL+P
Sbjct 18 RALFTFDPRTPDE-------LYFEEGDILYISDTSDSNWWKGTCRG------RTGLIPSN 64
Query 411 SFQQQREAMKQTIEEDKEPEKSGKLWCAKKNK-------KKRKKVLYNANKNDDYDNEEI 463
+Q E++ + E + L NK K LY A D EI
Sbjct 65 YVAEQAESIDNPMHEAAKRGNLSWLRECLDNKVGINGLDKAGNTSLYWACHGGHKDVVEI 124
Query 464 LTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKE 503
L + +Q L G +++ + L+NK
Sbjct 125 LLSQPNCELNQQNKLGDT-PLHAAAWKGYSDIVEMLLNKN 163
>sp|C3K5M3|PHNN_PSEFS Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Pseudomonas fluorescens (strain SBW25) OX=216595 GN=phnN
PE=3 SV=1
Length=190
Score = 64.7 bits (156), Expect = 1e-10, Method: Composition-based stats.
Identities = 30/155 (19%), Positives = 47/155 (30%), Gaps = 12/155 (8%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
R I LIGP G++ L + +R V R E G VS + F
Sbjct 3 GRLIYLIGPSGSGKDSLLDAARPRLAERGCRIVRRVI--TRSAEAVGEAAQGVSPEQFAT 60
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK----TLRNSDLKPYI 594
A G F + YG + + + +G L + R +
Sbjct 61 MQAEGAFALSWQANGLSYGIPRE-IDDWLAAGDDVL----VNGSRAHLAQTRERYPTLLV 115
Query 595 IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTR 629
+ + Q LR L G+ + + R
Sbjct 116 L-LLTVDQAVLRQRLIARGREALADIEARLARNAR 149
>sp|Q0K3R9|RBKTP_CUPNH Bifunctional ribose 1,5-bisphosphokinase-thymidine
phosphorylase OS=Cupriavidus necator (strain ATCC
17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier
337) OX=381666 GN=phnN PE=3 SV=1
Length=601
Score = 68.2 bits (165), Expect = 1e-10, Method: Composition-based stats.
Identities = 21/152 (14%), Positives = 48/152 (32%), Gaps = 13/152 (9%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++GP G++ L + A TR AG ++ V+ F
Sbjct 8 FFVVGPSGAGKDSLIDGARAALDGDYVFARRVITR---PDGSAGEEHEGVTEAEFARRQR 64
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK----TLRNSDLKPYIIFI 597
+G+F+ + YG + + + G+ + + L + ++ +
Sbjct 65 SGEFLVTWDAHDLRYGLPKSLMCE-LERGRNVVA----NGSRGVIAELAARLPRFVVVLV 119
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTR 629
P + L +A G+ + +
Sbjct 120 TAP-HDVLARRIAARGRESGDQVASRVARAGA 150
>sp|Q93646|SNT1_CAEEL Syntrophin-1 OS=Caenorhabditis elegans OX=6239
GN=stn-1 PE=1 SV=1
Length=440
Score = 67.8 bits (164), Expect = 1e-10, Method: Composition-based stats.
Identities = 20/87 (23%), Positives = 39/87 (45%), Gaps = 3/87 (3%)
Query 255 KIVRIEKARDIPLGATV---RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
+ VR+ K LG ++ R+ ++IS+I KG AA+++G L D ++ +NG +
Sbjct 44 RTVRVVKYDGNGLGISIKGGRDNNMPIVISKIFKGMAADQAGELFLDDVIISVNGENLLD 103
Query 312 KDVNEVFDLLSDMHGTLTFVLIPSQQI 338
E L + + ++
Sbjct 104 ASHEEAVRALKRAGRVVDLQVQYRRED 130
>sp|E7FDW2|PZR3B_DANRE E3 ubiquitin-protein ligase PDZRN3-B OS=Danio
rerio OX=7955 GN=pdzrn3b PE=1 SV=1
Length=1053
Score = 68.5 bits (166), Expect = 1e-10, Method: Composition-based stats.
Identities = 18/116 (16%), Positives = 45/116 (39%), Gaps = 12/116 (10%)
Query 252 ETVKIVRIEKARDIPLGATVRNE---------MDSVIISRIVKGGAAEKSGLLHEGDEVL 302
++V + ++ + + + +S+IV+ GAA+K G L D ++
Sbjct 245 KSVTAILHRESGSLGFNIVGGRPCVDNKDGTSNEGIFVSKIVEKGAADKEGGLQIHDRIM 304
Query 303 EINGIEIRGKDVNEVFDLLSDMHGTLTFVLI---PSQQIKPPPAKETVIHVKAHFD 355
E+NG ++ ++ + + ++ P + P + V+ + D
Sbjct 305 EVNGKDLSKATHDQAVEAFRMAKEPIMVQVLRRAPRPKPTGPTGEGQVVDISTQTD 360
Score = 51.2 bits (121), Expect = 3e-05, Method: Composition-based stats.
Identities = 20/72 (28%), Positives = 34/72 (47%), Gaps = 2/72 (3%)
Query 270 TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLT 329
T + + +S I A K G + EGD +++INGIEI+ + E LL+
Sbjct 440 TDDEDETGIYVSEIDPNSIAAKDGRIREGDRIIQINGIEIQNR--EEAVALLTSEEHPNV 497
Query 330 FVLIPSQQIKPP 341
+L+ +I+
Sbjct 498 CLLLARPEIQLD 509
>sp|Q9Z340|PARD3_RAT Partitioning defective 3 homolog OS=Rattus
norvegicus OX=10116 GN=Pard3 PE=1 SV=1
Length=1337
Score = 68.5 bits (166), Expect = 2e-10, Method: Composition-based stats.
Identities = 24/93 (26%), Positives = 47/93 (51%), Gaps = 9/93 (10%)
Query 257 VRIEKARDIPLGATVR------NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
++++K + LG ++ + + I+ GAA + G L GD ++E+NG+++
Sbjct 462 IQLKKGTE-GLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLA 520
Query 311 GKDVNEVFDLLS--DMHGTLTFVLIPSQQIKPP 341
GK EV LL M GT++ ++ ++ P
Sbjct 521 GKSQEEVVSLLRSTKMEGTVSLLVFRQEEAFHP 553
Score = 53.9 bits (128), Expect = 4e-06, Method: Composition-based stats.
Identities = 28/141 (20%), Positives = 57/141 (40%), Gaps = 15/141 (11%)
Query 228 AEQEMQLEPI--TDERVYESIGQYGGETVKIVRIEKARDIPLGATV------RNEMDSVI 279
E ++EP+ D + + VK+V++ PLG V ++
Sbjct 244 EEDSSRVEPVGHADTGLENMPNFSLDDMVKLVQVP-NDGGPLGIHVVPFSARGGRTLGLL 302
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM--HGTLTFVLIPSQQ 337
+ R+ KGG AE+ L HE D ++ IN ++R + + + + F ++P+
Sbjct 303 VKRLEKGGKAEQENLFHENDCIVRINDGDLRNRRFEQAQHMFRQAMRARVIWFHVVPAAN 362
Query 338 IKPPPAKETVIHVKAHFDYDP 358
+ + + + +Y P
Sbjct 363 KE----QYEQLSQREMNNYSP 379
Score = 51.2 bits (121), Expect = 3e-05, Method: Composition-based stats.
Identities = 27/149 (18%), Positives = 51/149 (34%), Gaps = 7/149 (5%)
Query 183 ISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERV 242
+ A +EV ++L+ + L + + Q + DE +
Sbjct 517 VDLAGKSQEEVVSLLRSTKMEGTVSLLVFRQEEAFHPREMNAEPSQMQSPKETKAEDEDI 576
Query 243 YESIGQYGGETVKIVRIEKARDIPLGATVRNEMD-------SVIISRIVKGGAAEKSGLL 295
+ V + + LG +V+ + + I+ GGAA K G L
Sbjct 577 VLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRL 636
Query 296 HEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
D+++ +NG + GK E + L
Sbjct 637 RVNDQLIAVNGESLLGKANQEAMETLRRS 665
>sp|A6SU94|PHNN_JANMA Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Janthinobacterium sp. (strain Marseille) OX=375286 GN=phnN
PE=3 SV=1
Length=453
Score = 67.4 bits (163), Expect = 2e-10, Method: Composition-based stats.
Identities = 34/224 (15%), Positives = 76/224 (34%), Gaps = 30/224 (13%)
Query 455 NDDYDNEEILTYEEMSLYHQP-----ANRKRPIILIGPQNCGQNELRQRLMNKE--KDRF 507
++Y + ++ + Q + R +GP G++ L + ++
Sbjct 245 REEYPGAPFVEWQRIPFSGQGERASLPHSGRIFFCVGPSGVGKDSLLNWVREHSAGDEKL 304
Query 508 ASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVI 567
A TR+ + E V +F A G+F + YG + +
Sbjct 305 VFAQRTITRATQANEAHEA----VDTASFWRLAAGGQFAMVWQANDLCYGIRRG-IEADL 359
Query 568 NSGKICLLSLRTQSLK----TLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELRE 623
+G+ ++ + L + +I+I S+ LR L + P L+
Sbjct 360 KAGRDVVI----NGSRAYVPQLLQAFPDAIVIWIDA-SENLLRERLEARQREQGPALLKR 414
Query 624 IIEKTREMEQNNGHYFDTAIVNSDLDKAY----QELLRLINKLD 663
+ ++ +E + ++ D A Q+LL ++ +
Sbjct 415 L-KRAKEFAPSEQ----AQVIRLDNSGALEAGGQKLLDILRQAK 453
>sp|Q9CZG9|PDZ11_MOUSE PDZ domain-containing protein 11 OS=Mus
musculus OX=10090 GN=Pdzd11 PE=1 SV=1
Length=140
Score = 62.8 bits (151), Expect = 2e-10, Method: Composition-based stats.
Identities = 24/113 (21%), Positives = 49/113 (43%), Gaps = 10/113 (9%)
Query 231 EMQLEP---ITDERVY--ESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISR 282
+ P ERVY + + +IV ++K LG +R + IS+
Sbjct 17 AYENPPAWIPPHERVYHPDYNNELTQFLPRIVTLKKPPGAQLGFNIRGGKASQLGIFISK 76
Query 283 IVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG-TLTFVLIP 334
++ A ++G L EGD+VL +N ++ + + ++ ++L ++ P
Sbjct 77 VIPDSDAHRAG-LQEGDQVLAVNDVDFQDIEHSKAVEILKTAREISMRVRFFP 128
>sp|Q99NH2|PARD3_MOUSE Partitioning defective 3 homolog OS=Mus
musculus OX=10090 GN=Pard3 PE=1 SV=2
Length=1333
Score = 68.2 bits (165), Expect = 2e-10, Method: Composition-based stats.
Identities = 24/93 (26%), Positives = 47/93 (51%), Gaps = 9/93 (10%)
Query 257 VRIEKARDIPLGATVR------NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
++++K + LG ++ + + I+ GAA + G L GD ++E+NG+++
Sbjct 462 IQLKKGTE-GLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLA 520
Query 311 GKDVNEVFDLLS--DMHGTLTFVLIPSQQIKPP 341
GK EV LL M GT++ ++ ++ P
Sbjct 521 GKSQEEVVSLLRSTKMEGTVSLLVFRQEEAFHP 553
Score = 53.1 bits (126), Expect = 9e-06, Method: Composition-based stats.
Identities = 24/105 (23%), Positives = 44/105 (42%), Gaps = 9/105 (9%)
Query 228 AEQEMQLEPI--TDERVYESIGQYGGETVKIVRIEKARDIPLGATV------RNEMDSVI 279
E ++EP+ D + + VK+V++ PLG V ++
Sbjct 244 EEDSSRVEPVGHADTGLENMPNFSLDDMVKLVQVP-NDGGPLGIHVVPFSARGGRTLGLL 302
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
+ R+ KGG AE+ L HE D ++ IN ++R + + +
Sbjct 303 VKRLEKGGKAEQENLFHENDCIVRINDGDLRNRRFEQAQHMFRQA 347
Score = 50.4 bits (119), Expect = 6e-05, Method: Composition-based stats.
Identities = 28/149 (19%), Positives = 51/149 (34%), Gaps = 7/149 (5%)
Query 183 ISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERV 242
+ A +EV ++L+ + L + + Q + DE V
Sbjct 517 VDLAGKSQEEVVSLLRSTKMEGTVSLLVFRQEEAFHPREMNAEPSQMQTPKETKAEDEDV 576
Query 243 YESIGQYGGETVKIVRIEKARDIPLGATVRNEMD-------SVIISRIVKGGAAEKSGLL 295
+ V + + LG +V+ + + I+ GGAA K G L
Sbjct 577 VLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRL 636
Query 296 HEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
D+++ +NG + GK E + L
Sbjct 637 RVNDQLIAVNGESLLGKANQEAMETLRRS 665
>sp|Q6QA76|PDZ11_PIG PDZ domain-containing protein 11 OS=Sus scrofa
OX=9823 GN=PDZD11 PE=2 SV=1
Length=140
Score = 62.8 bits (151), Expect = 2e-10, Method: Composition-based stats.
Identities = 24/113 (21%), Positives = 49/113 (43%), Gaps = 10/113 (9%)
Query 231 EMQLEP---ITDERVY--ESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISR 282
+ P ERVY + + +IV ++K LG +R + IS+
Sbjct 17 AYENPPAWIPPHERVYHPDYNNELTQFLPRIVTLKKPPGAQLGFNIRGGKASQLGIFISK 76
Query 283 IVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG-TLTFVLIP 334
++ A ++G L EGD+VL +N ++ + + ++ ++L ++ P
Sbjct 77 VIPDSDAHRAG-LQEGDQVLAVNDVDFQDIEHSKAVEILKTAREISMRVRFFP 128
>sp|Q32LE7|PDZ11_BOVIN PDZ domain-containing protein 11 OS=Bos
taurus OX=9913 GN=PDZD11 PE=2 SV=1
Length=140
Score = 62.8 bits (151), Expect = 2e-10, Method: Composition-based stats.
Identities = 24/113 (21%), Positives = 49/113 (43%), Gaps = 10/113 (9%)
Query 231 EMQLEP---ITDERVY--ESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISR 282
+ P ERVY + + +IV ++K LG +R + IS+
Sbjct 17 AYENPPAWIPPHERVYHPDYNNELTQFLPRIVTLKKPPGAQLGFNIRGGKASQLGIFISK 76
Query 283 IVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG-TLTFVLIP 334
++ A ++G L EGD+VL +N ++ + + ++ ++L ++ P
Sbjct 77 VIPDSDAHRAG-LQEGDQVLAVNDVDFQDIEHSKAVEILKTAREISMRVRFFP 128
>sp|Q9ES64|USH1C_MOUSE Harmonin OS=Mus musculus OX=10090 GN=Ush1c
PE=1 SV=1
Length=910
Score = 67.8 bits (164), Expect = 2e-10, Method: Composition-based stats.
Identities = 26/82 (32%), Positives = 46/82 (56%), Gaps = 2/82 (2%)
Query 245 SIGQYGGETVKIVRIEK--ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVL 302
S Q G+ V+++RI+K + D+ L V + + V++S + +GGAAE+ G + +GDE++
Sbjct 744 SPEQIAGKDVRLLRIKKEGSLDLALEGGVDSPVGKVVVSAVYEGGAAERHGGVVKGDEIM 803
Query 303 EINGIEIRGKDVNEVFDLLSDM 324
ING + + E L
Sbjct 804 AINGKIVTDYTLAEAEAALQKA 825
Score = 63.2 bits (152), Expect = 6e-09, Method: Composition-based stats.
Identities = 31/118 (26%), Positives = 55/118 (47%), Gaps = 5/118 (4%)
Query 234 LEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAE 290
L P+ + Y+ + +K VR+++ LG +VR ++ + IS ++KGG A+
Sbjct 65 LIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKGGQAD 124
Query 291 KSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVI 348
G L GDE++ ING I EV +L+ T++ + I + E +
Sbjct 125 SVG-LQVGDEIVRINGYSISSCTHEEVINLIR-TKKTVSIKVRHIGLIPVKSSPEESL 180
Score = 54.3 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 20/84 (24%), Positives = 39/84 (46%), Gaps = 5/84 (6%)
Query 255 KIVRIEKARDIPLGATVRN---EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
K V I LG ++ + + + +S + G + + G L GD+++E+NGI+
Sbjct 210 KKVFISLVGSRGLGCSISSGPIQKPGIFVSHVKPGSLSAEVG-LETGDQIVEVNGIDFTN 268
Query 312 KDVNEVFDLLSDMHGTLTFVLIPS 335
D E ++L +LT ++
Sbjct 269 LDHKEAVNVLK-SSRSLTISIVAG 291
>sp|Q9NB04|PATJ_DROME Patj homolog OS=Drosophila melanogaster
OX=7227 GN=Patj PE=1 SV=2
Length=871
Score = 67.8 bits (164), Expect = 2e-10, Method: Composition-based stats.
Identities = 30/143 (21%), Positives = 55/143 (38%), Gaps = 9/143 (6%)
Query 233 QLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV------RNEMDSVIISRIVKG 286
+ + D + ET K+ K LG T+ + E+ + + + G
Sbjct 294 ETSMLIDPNIDLEELLALPETEKLQVELKKDANGLGITIAGYVCEKEELSGIFVKSVSPG 353
Query 287 GAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKET 346
AA+ SG + D ++E++G ++G ++ +LL + L ++ P E
Sbjct 354 SAADLSGRIRVNDRIIEVDGQSLQGYSNHQAVELLKKSGQVVNLRL---ERYLRGPKFEQ 410
Query 347 VIHVKAHFDYDPSDDPYVPCREL 369
+ A D PS P P R
Sbjct 411 LQQAIAANDKLPSSAPGTPSRAP 433
Score = 62.8 bits (151), Expect = 8e-09, Method: Composition-based stats.
Identities = 38/234 (16%), Positives = 87/234 (37%), Gaps = 6/234 (3%)
Query 114 SPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHM 173
S + + +IE + + + Q+ E +S +L ++Q+ F+ + ++++
Sbjct 4 SADISSALQQIEAVKKGIDESDDPKLQMQTAESLSTILGILQDPVFRTIVHVQDSLSELN 63
Query 174 NKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQ 233
+ + ++ N D+ VL + + ++ H + + DK +
Sbjct 64 AQLAQHPSMLPNDFDIDVAGNLVLSLNGGEVMYDFDEQRSSSHSHSAPGSPDKSGGVGEE 123
Query 234 LEPITDERVYESIGQYGGETVKIVR----IEKARDIPLGATVRNEMDSVIISRIVKGGAA 289
P + + ++ + + G + VI+ I+ GG A
Sbjct 124 PRPQSQNSKGAGVADLYATDYAQIQAIELVNDGTGLGFGI-IGARNSGVIVKTILPGGVA 182
Query 290 EKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL-IPSQQIKPPP 342
+K G L GD +L+I + + +V +L + V+ P +Q P P
Sbjct 183 DKDGRLRSGDHILQIGDVNLHEMVSEQVAAVLRQSGTHVRLVVARPVEQSVPTP 236
Score = 59.7 bits (143), Expect = 7e-08, Method: Composition-based stats.
Identities = 31/147 (21%), Positives = 54/147 (37%), Gaps = 20/147 (14%)
Query 230 QEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDS-------VIISR 282
+ LEP+T ++ S Q I+ + K D LG ++ + D ++I
Sbjct 709 KSRSLEPLTGLAMWSSQPQ-------IIELVKG-DRGLGFSILDYQDPLDPNDTLIVIRS 760
Query 283 IVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTL----TFVLIPSQQI 338
+V GG A+ G L GD +L +N I + +++ L + +P
Sbjct 761 LVPGGVAQLDGRLIPGDRLLFVNSINLENASLDQAVQALKGASKGVVRIGVAKPLPMTDN 820
Query 339 KPPPAKETVIHVKAHFDYDPSDDPYVP 365
+ D PS P +P
Sbjct 821 SLKACSNASTTSEETLDAQPSP-PALP 846
Score = 52.8 bits (125), Expect = 9e-06, Method: Composition-based stats.
Identities = 33/157 (21%), Positives = 67/157 (43%), Gaps = 16/157 (10%)
Query 230 QEMQLEPITDERVYESIGQYG---GETVKIV--RIEKARDIPLGATVRNEMD-------- 276
+ ++D+ E I ++ G V+++ +I+K LG ++ +D
Sbjct 528 KYYTDPELSDDAETEIIRKWQKIVGSDVEVIVAQIKKFAVGGLGISLEGTVDVEGGREVR 587
Query 277 -SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
I I+ G +G+L GDE+LE+NG + G + EV +L ++ + V +
Sbjct 588 PHHYIRSILPDGPVGVNGVLRSGDELLEVNGERLLGMNHLEVVAILKELPLDVRMVCGRN 647
Query 336 QQIKPPPAKETVI-HVKAHFD-YDPSDDPYVPCRELG 370
+ P + + + +F+ P+ D V + G
Sbjct 648 RNSSLLPFSDDTLKKLSNNFENLLPATDRLVKAKSDG 684
>sp|Q62662|FRK_RAT Tyrosine-protein kinase FRK OS=Rattus norvegicus
OX=10116 GN=Frk PE=1 SV=3
Length=506
Score = 67.0 bits (162), Expect = 2e-10, Method: Composition-based stats.
Identities = 28/128 (22%), Positives = 41/128 (32%), Gaps = 21/128 (16%)
Query 334 PSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAY 393
P P + + A FDY+ LSF GD L V+ WW A
Sbjct 32 PGAYCPPEANRSQGQYFVALFDYEARTAED-------LSFHAGDKLQVLDTSHEGWWLAR 84
Query 394 RE---GDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLY 450
G Q L G +P + R + + A K K++LY
Sbjct 85 HLEKKGPGLGQQLQGYIPSNYVAEDR-----------SLQAEPWFFGAIKRADAEKQLLY 133
Query 451 NANKNDDY 458
+ N+ +
Sbjct 134 SENQTGAF 141
>sp|Q9Y6V0|PCLO_HUMAN Protein piccolo OS=Homo sapiens OX=9606
GN=PCLO PE=1 SV=5
Length=5142
Score = 67.8 bits (164), Expect = 3e-10, Method: Composition-based stats.
Identities = 25/77 (32%), Positives = 40/77 (52%), Gaps = 4/77 (5%)
Query 257 VRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
+RI ++IP + I++I+ GG+AE++G L EG +VLE NGI + K E
Sbjct 4515 IRIVGGKEIP----GHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWNGIPLTSKTYEE 4570
Query 317 VFDLLSDMHGTLTFVLI 333
V ++S G +
Sbjct 4571 VQSIISQQSGEAEICVR 4587
>sp|Q7S6J4|HSE1_NEUCR Class E vacuolar protein-sorting machinery
protein hse1 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A
/ CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=hse1
PE=3 SV=1
Length=745
Score = 67.4 bits (163), Expect = 3e-10, Method: Composition-based stats.
Identities = 43/188 (23%), Positives = 75/188 (40%), Gaps = 32/188 (17%)
Query 336 QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYRE 395
Q + TV V+A +D+ PS+ L F+KGD++ V+ +WW +
Sbjct 229 QPVPSSTTAATVSRVRALYDFVPSEPGE-------LEFKKGDVIAVLKSVYKDWWSGSLK 281
Query 396 GDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKN 455
G G+ P ++ + + ++ E + +++ KN +K +L N
Sbjct 282 GKT------GIFPLNYVEKLADPTPEELQR--EAQMEAEVFAEIKNVEKLLTLLSAGNTG 333
Query 456 DDYDNEEILTYEEMSLYHQP-ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHT 514
++ E E LYHQ A R + I LI +++KD F
Sbjct 334 PREEDNE----EISKLYHQTLAIRPKLIKLI------------EKYSQKKDDFTQLNEKF 377
Query 515 TRSRRDQE 522
++RRD E
Sbjct 378 IKARRDYE 385
>sp|Q57D38|PHNN_BRUAB Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Brucella abortus biovar 1 (strain 9-941) OX=262698 GN=phnN
PE=3 SV=1
Length=192
Score = 63.2 bits (152), Expect = 4e-10, Method: Composition-based stats.
Identities = 26/146 (18%), Positives = 54/146 (37%), Gaps = 7/146 (5%)
Query 482 IILIGPQNCGQNELRQ--RLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
+ ++GP G++ + R+ RF TR++ D+ + F
Sbjct 11 VAVVGPSGAGKDTIMDAARVALSGDMRFHFVRRIITRTQMPGT---EDHDSLDEADFARA 67
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
G+F H + YG ++ I G + + ++ + L +R ++ I+
Sbjct 68 AGEGRFALHWQAHGLRYGLPK-TLDDEIAGGAVVIANVSRRVLSDIRRLYTSRSVVVISA 126
Query 600 PSQERLRALLAKEGKNPKPEELREII 625
+ E L LA G+ + E +
Sbjct 127 RT-EVLAQRLASRGRESREEIAARLA 151
>sp|C0RJ73|PHNN_BRUMB Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Brucella melitensis biotype 2 (strain ATCC 23457) OX=546272
GN=phnN PE=3 SV=1
Length=192
Score = 62.8 bits (151), Expect = 5e-10, Method: Composition-based stats.
Identities = 26/146 (18%), Positives = 54/146 (37%), Gaps = 7/146 (5%)
Query 482 IILIGPQNCGQNELRQ--RLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
+ ++GP G++ + R+ RF TR++ D+ + F
Sbjct 11 VAVVGPSGAGKDTIMDAARVALSGDMRFHFVRRIITRTQMPGT---EDHDSLDEADFARA 67
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAP 599
G+F H + YG ++ I G + + ++ + L +R ++ I+
Sbjct 68 AGEGRFALHWQAHGLRYGLPK-TLDDEIAGGAVVIANVSRRVLSDIRRLYTSRSVVVISA 126
Query 600 PSQERLRALLAKEGKNPKPEELREII 625
+ E L LA G+ + E +
Sbjct 127 RT-EVLAQRLASRGRESREEIAARLA 151
>sp|Q7KRY7|SCRIB_DROME Protein lap4 OS=Drosophila melanogaster
OX=7227 GN=scrib PE=1 SV=1
Length=1851
Score = 66.6 bits (161), Expect = 6e-10, Method: Composition-based stats.
Identities = 21/100 (21%), Positives = 44/100 (44%), Gaps = 9/100 (9%)
Query 256 IVRIEKARDIPLGATVR-------NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIE 308
++R + + + ++ D + ISRI +GG A + G + GD V+ ING +
Sbjct 932 LIRDQIGQGLGFSIAGGKGSPPFKDDCDGIFISRITEGGLAYRDGKIMVGDRVMAINGND 991
Query 309 IRGKDVNEVFDLLSDMHGTLTFVLIPSQQ--IKPPPAKET 346
+ + L++ + VL + ++PP + +
Sbjct 992 MTEAHHDAAVACLTEPQRFVRLVLQREYRGPLEPPTSPRS 1031
Score = 62.8 bits (151), Expect = 1e-08, Method: Composition-based stats.
Identities = 36/185 (19%), Positives = 60/185 (32%), Gaps = 26/185 (14%)
Query 168 AITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKV 227
A+TV++NK P P+ A V + E + + + L++ + V
Sbjct 1184 AVTVNVNKPQPDLPMFPAAPTELGRVTETITKSTFTET--VMTRITDNQLAEPLISEEVV 1241
Query 228 AEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGG 287
+ + GG V + IS IV GG
Sbjct 1242 ---------LPKNQGSLGFSIIGGTDHSCVPF------------GTREPGIFISHIVPGG 1280
Query 288 AAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV 347
A K G L GD +L++N ++ + L + + Q PP + V
Sbjct 1281 IASKCGKLRMGDRILKVNEADVSKATHQDAVLELLKPGDEIKLTI---QHDPLPPGFQEV 1337
Query 348 IHVKA 352
+ KA
Sbjct 1338 LLSKA 1342
Score = 62.4 bits (150), Expect = 1e-08, Method: Composition-based stats.
Identities = 24/113 (21%), Positives = 44/113 (39%), Gaps = 12/113 (11%)
Query 232 MQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEM------------DSVI 279
++L DE + V + KA LG ++ + + V
Sbjct 1312 LELLKPGDEIKLTIQHDPLPPGFQEVLLSKAEGERLGMHIKGGLNGQRGNPADPSDEGVF 1371
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+S+I GAA + G L G +LE+NG + G + ++L + + V+
Sbjct 1372 VSKINSVGAARRDGRLKVGMRLLEVNGHSLLGASHQDAVNVLRNAGNEIQLVV 1424
Score = 60.1 bits (144), Expect = 6e-08, Method: Composition-based stats.
Identities = 22/113 (19%), Positives = 44/113 (39%), Gaps = 6/113 (5%)
Query 228 AEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGAT-----VRNEMDSVIISR 282
A + + D + + + I R + + + + D + ISR
Sbjct 706 AGKTAEASTDPDNLDGVTELRLEQYEIHIERTAAGLGLSIAGGKGSTPFKGDDDGIFISR 765
Query 283 IVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ + G A+ +G L GD+V+++NGI + D + +L L V+
Sbjct 766 VTEAGPADLAG-LKVGDKVIKVNGIVVVDADHYQAVQVLKACGAVLVLVVQRE 817
>sp|Q3MHQ0|USH1C_BOVIN Harmonin OS=Bos taurus OX=9913 GN=USH1C
PE=2 SV=1
Length=551
Score = 65.8 bits (159), Expect = 6e-10, Method: Composition-based stats.
Identities = 25/82 (30%), Positives = 46/82 (56%), Gaps = 2/82 (2%)
Query 245 SIGQYGGETVKIVRIEK--ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVL 302
+ Q G+ V+++R++K A D+ L V + + V++S + +GGAAE+ G + +GDE++
Sbjct 444 TPEQIMGKDVRLLRVKKEGALDLALEGGVDSPIGKVVVSAVYEGGAAERHGGIVKGDEIM 503
Query 303 EINGIEIRGKDVNEVFDLLSDM 324
ING + + E L
Sbjct 504 AINGKIVTDYTLAEAEAALQKA 525
Score = 61.2 bits (147), Expect = 2e-08, Method: Composition-based stats.
Identities = 32/123 (26%), Positives = 56/123 (46%), Gaps = 10/123 (8%)
Query 234 LEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAE 290
L P+ + Y+ + +K VR+++ LG +VR ++ + IS ++K G A+
Sbjct 65 LIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKDGQAD 124
Query 291 KSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL-----IPSQQIKPPPAKE 345
G L GDE++ ING I EV +L+ T++ + IP + P K
Sbjct 125 SVG-LQVGDEIVRINGYSISSCTHEEVINLIR-TKKTVSIKVRHIGLIPVKSSPDEPLKW 182
Query 346 TVI 348
+
Sbjct 183 QYV 185
Score = 53.5 bits (127), Expect = 4e-06, Method: Composition-based stats.
Identities = 21/100 (21%), Positives = 43/100 (43%), Gaps = 4/100 (4%)
Query 255 KIVRIEKARDIPLGATVRN---EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
K V I LG ++ + + + IS + G + + G L GD+++E+NGI+
Sbjct 210 KKVFISLVGSRGLGCSISSGPIQKPGIFISHVKPGSLSAEVG-LETGDQIVEVNGIDFSN 268
Query 312 KDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVK 351
D E ++L ++ + + +E + V+
Sbjct 269 LDHKEAVNVLKSSRSLTISIVAGAGRELFMTDQERLAEVR 308
>sp|Q922K9|FRK_MOUSE Tyrosine-protein kinase FRK OS=Mus musculus
OX=10090 GN=Frk PE=1 SV=3
Length=512
Score = 65.8 bits (159), Expect = 7e-10, Method: Composition-based stats.
Identities = 28/128 (22%), Positives = 41/128 (32%), Gaps = 21/128 (16%)
Query 334 PSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAY 393
P P + + A FDY LSF+ GD L V+ WW A
Sbjct 38 PEAPRSQEPERSHGQYFVALFDYQARTAED-------LSFRAGDKLQVLDTSHEGWWLAR 90
Query 394 RE---GDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLY 450
G Q L G +P + R + + A K K++LY
Sbjct 91 HLEKKGTGLGQQLQGYIPSNYVAEDR-----------SLQAEPWFFGAIKRADAEKQLLY 139
Query 451 NANKNDDY 458
+ N+ +
Sbjct 140 SENQTGAF 147
>sp|Q9CSB4|PAR3L_MOUSE Partitioning defective 3 homolog B OS=Mus
musculus OX=10090 GN=Pard3b PE=1 SV=2
Length=1203
Score = 65.8 bits (159), Expect = 9e-10, Method: Composition-based stats.
Identities = 27/121 (22%), Positives = 49/121 (40%), Gaps = 13/121 (11%)
Query 229 EQEMQLE-----PITDERVYESIGQYGGETVKI-VRIEKARDIPLGATVR------NEMD 276
+ ++ P + KI + ++K + LG TV +
Sbjct 350 SKSPRVPRLGRKPSSPSLSPLMGFGSKKNAKKIKIDLKKGPE-GLGFTVVTRDSSIHGPG 408
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQ 336
+ + I+ GAA K G L GD +LE+NG ++ G+ E+ +L T L+ ++
Sbjct 409 PIFVKNILPKGAAVKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETVSLVIAR 468
Query 337 Q 337
Q
Sbjct 469 Q 469
Score = 50.1 bits (118), Expect = 8e-05, Method: Composition-based stats.
Identities = 29/141 (21%), Positives = 53/141 (38%), Gaps = 18/141 (13%)
Query 229 EQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD-------SVIIS 281
+E++ EP ES Q E + + + LG +++ + I
Sbjct 475 PRELKGEPDCYALSLESSEQLTLE----IPLNDSGSAGLGVSLKGNKSRETGTDLGIFIK 530
Query 282 RIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM-------HGTLTFVLIP 334
I+ GGAA K G L D+++ +NG + GK +E + L G + V++
Sbjct 531 SIIHGGAAFKDGRLRMNDQLIAVNGETLLGKSNHEAMETLRRSMSMEGNIRGMIQLVILR 590
Query 335 SQQIKPPPAKETVIHVKAHFD 355
+ E + F+
Sbjct 591 RPERPLEELSECGALSRPGFE 611
Score = 40.8 bits (94), Expect = 0.053, Method: Composition-based stats.
Identities = 18/104 (17%), Positives = 40/104 (38%), Gaps = 11/104 (11%)
Query 246 IGQYGGETVKIVRIEKARDIPLGA-------TVRNEMDSVIISRIVKGGAAEKSGLLHEG 298
+ + V I PLG ++ + + I I + ++ GL E
Sbjct 193 PKDELSDMTRAVEIS-GEGDPLGIHVVPFFSSLSGRILGLFIRGIEENSRCKQEGLFQEN 251
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDM--HGTLTF-VLIPSQQIK 339
+ +++IN +E+ K + D+ ++ VL+P + +
Sbjct 252 ECIVKINNVELLDKTFAQAQDVFRQAMKSPSVILHVLLPQNREQ 295
>sp|Q925E1|SNTG1_MOUSE Gamma-1-syntrophin OS=Mus musculus OX=10090
GN=Sntg1 PE=2 SV=2
Length=517
Score = 65.1 bits (157), Expect = 1e-09, Method: Composition-based stats.
Identities = 35/123 (28%), Positives = 54/123 (44%), Gaps = 11/123 (9%)
Query 213 NTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVR 272
P L LA D + QE + ++ E Y + V I + G +++
Sbjct 22 QEPFKVRLHLARDLLMLQEQDVLCVSGEPFYSGE--------RTVTIRRQTVGGFGLSIK 73
Query 273 NEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLT 329
+ V+IS+I K AE SGLL GD +L+INGI +R EV +L + +T
Sbjct 74 GGAEHNIPVVISKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGEEVT 133
Query 330 FVL 332
+
Sbjct 134 LTV 136
>sp|A5PKA5|SNX27_BOVIN Sorting nexin-27 OS=Bos taurus OX=9913
GN=SNX27 PE=2 SV=1
Length=541
Score = 65.1 bits (157), Expect = 1e-09, Method: Composition-based stats.
Identities = 29/126 (23%), Positives = 57/126 (45%), Gaps = 18/126 (14%)
Query 255 KIVRIEKARDIPLGATVRNEM----------DSVI-----ISRIVKGGAAEKSGLLHEGD 299
++VRI K+ + G VR ++ + +S ++ GGAA+++G + +GD
Sbjct 42 RVVRIVKS-ESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAG-VRKGD 99
Query 300 EVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPS 359
+LE+NG+ + G +V DL+ L ++ + + + F YD +
Sbjct 100 RILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSF-YDYT 158
Query 360 DDPYVP 365
+ VP
Sbjct 159 EKQAVP 164
>sp|Q8K4V4|SNX27_RAT Sorting nexin-27 OS=Rattus norvegicus OX=10116
GN=Snx27 PE=1 SV=2
Length=539
Score = 65.1 bits (157), Expect = 1e-09, Method: Composition-based stats.
Identities = 29/126 (23%), Positives = 57/126 (45%), Gaps = 18/126 (14%)
Query 255 KIVRIEKARDIPLGATVRNEM----------DSVI-----ISRIVKGGAAEKSGLLHEGD 299
++VRI K+ + G VR ++ + +S ++ GGAA+++G + +GD
Sbjct 40 RVVRIVKS-ESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAG-VRKGD 97
Query 300 EVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPS 359
+LE+NG+ + G +V DL+ L ++ + + + F YD +
Sbjct 98 RILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSF-YDYT 156
Query 360 DDPYVP 365
+ VP
Sbjct 157 EKQAVP 162
>sp|Q9Y6N9|USH1C_HUMAN Harmonin OS=Homo sapiens OX=9606 GN=USH1C
PE=1 SV=3
Length=552
Score = 65.1 bits (157), Expect = 1e-09, Method: Composition-based stats.
Identities = 24/82 (29%), Positives = 45/82 (55%), Gaps = 2/82 (2%)
Query 245 SIGQYGGETVKIVRIEK--ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVL 302
+ Q G+ V+++RI+K + D+ L V + + V++S + + GAAE+ G + +GDE++
Sbjct 444 TPEQIMGKDVRLLRIKKEGSLDLALEGGVDSPIGKVVVSAVYERGAAERHGGIVKGDEIM 503
Query 303 EINGIEIRGKDVNEVFDLLSDM 324
ING + + E L
Sbjct 504 AINGKIVTDYTLAEAEAALQKA 525
Score = 61.6 bits (148), Expect = 1e-08, Method: Composition-based stats.
Identities = 29/103 (28%), Positives = 51/103 (50%), Gaps = 5/103 (5%)
Query 234 LEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAE 290
L P+ + Y+ + +K VR+++ LG +VR ++ + IS ++KGG A+
Sbjct 65 LIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKGGQAD 124
Query 291 KSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
G L GDE++ ING I EV +L+ T++ +
Sbjct 125 SVG-LQVGDEIVRINGYSISSCTHEEVINLIR-TKKTVSIKVR 165
Score = 53.9 bits (128), Expect = 4e-06, Method: Composition-based stats.
Identities = 20/84 (24%), Positives = 40/84 (48%), Gaps = 5/84 (6%)
Query 255 KIVRIEKARDIPLGATVRN---EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
K V I LG ++ + + + IS + G + + G L GD+++E+NG++
Sbjct 210 KKVFISLVGSRGLGCSISSGPIQKPGIFISHVKPGSLSAEVG-LEIGDQIVEVNGVDFSN 268
Query 312 KDVNEVFDLLSDMHGTLTFVLIPS 335
D E ++L +LT ++ +
Sbjct 269 LDHKEAVNVLK-SSRSLTISIVAA 291
>sp|Q3UHD6|SNX27_MOUSE Sorting nexin-27 OS=Mus musculus OX=10090
GN=Snx27 PE=1 SV=2
Length=539
Score = 65.1 bits (157), Expect = 1e-09, Method: Composition-based stats.
Identities = 29/126 (23%), Positives = 57/126 (45%), Gaps = 18/126 (14%)
Query 255 KIVRIEKARDIPLGATVRNEM----------DSVI-----ISRIVKGGAAEKSGLLHEGD 299
++VRI K+ + G VR ++ + +S ++ GGAA+++G + +GD
Sbjct 40 RVVRIVKS-ESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAG-VRKGD 97
Query 300 EVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPS 359
+LE+NG+ + G +V DL+ L ++ + + + F YD +
Sbjct 98 RILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSF-YDYT 156
Query 360 DDPYVP 365
+ VP
Sbjct 157 EKQAVP 162
>sp|A1T0U7|PHNN_PSYIN Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Psychromonas ingrahamii (strain DSM 17664 / CCUG 51855
/ 37) OX=357804 GN=phnN PE=3 SV=1
Length=196
Score = 62.0 bits (149), Expect = 1e-09, Method: Composition-based stats.
Identities = 37/205 (18%), Positives = 78/205 (38%), Gaps = 25/205 (12%)
Query 468 EMSLYHQPANRKRPIILIGPQNCGQNEL----RQRLMNKEKDRFASAVPHTTRSRRDQEV 523
S+ + ++ + +IG G++ L RQRL N+ A + TR E+
Sbjct 2 PNSIIKKYPSKGKLFYVIGASGVGKDSLLHYARQRLANE---SLVFAHRYITRPV---EL 55
Query 524 AGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK 583
G ++ ++++ F + G F + + YG ++ V + + G ++ +
Sbjct 56 KGENHIQLTKEEFNNRLQRGCFKFNWHSHELDYGIGVE-VDRWLMQGSNVVI----NGSR 110
Query 584 T-LRNS---DLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYF 639
L + + I S L L K G+ + + I + + +
Sbjct 111 GYLNTAVALHPGLVPVLIQVDS-NLLHERLIKRGRETLEQIEKRIQRAQAFVGLTSPNM- 168
Query 640 DTAIV--NSDLDKAYQELLRLINKL 662
I+ NS+L A ++L+ L+
Sbjct 169 --QIIENNSELSVAGEQLVSLLRNQ 191
>sp|Q9NSN8|SNTG1_HUMAN Gamma-1-syntrophin OS=Homo sapiens OX=9606
GN=SNTG1 PE=1 SV=1
Length=517
Score = 65.1 bits (157), Expect = 1e-09, Method: Composition-based stats.
Identities = 34/123 (28%), Positives = 54/123 (44%), Gaps = 11/123 (9%)
Query 213 NTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVR 272
P L LA D + QE + ++ E Y + V I + G +++
Sbjct 22 QEPFKVRLHLAKDILMIQEQDVICVSGEPFYSGE--------RTVTIRRQTVGGFGLSIK 73
Query 273 NEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLT 329
+ V++S+I K AE SGLL GD +L+INGI +R EV +L + +T
Sbjct 74 GGAEHNIPVVVSKISKEQRAELSGLLFIGDAILQINGINVRKCRHEEVVQVLRNAGEEVT 133
Query 330 FVL 332
+
Sbjct 134 LTV 136
>sp|Q9PU36|PCLO_CHICK Protein piccolo (Fragment) OS=Gallus gallus
OX=9031 GN=PCLO PE=2 SV=1
Length=5120
Score = 65.5 bits (158), Expect = 1e-09, Method: Composition-based stats.
Identities = 23/77 (30%), Positives = 40/77 (52%), Gaps = 4/77 (5%)
Query 257 VRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
+R+ ++IP + I++++ GG AE++G L EG +VLE NGI + GK E
Sbjct 4433 IRVVGGKEIP----GSSGEIGAYIAKVLPGGNAEQTGKLIEGMQVLEWNGIPLTGKTYEE 4488
Query 317 VFDLLSDMHGTLTFVLI 333
V +++ G +
Sbjct 4489 VQNIIIQQCGEAEICVR 4505
>sp|Q9UPQ7|PZRN3_HUMAN E3 ubiquitin-protein ligase PDZRN3 OS=Homo
sapiens OX=9606 GN=PDZRN3 PE=1 SV=2
Length=1066
Score = 65.1 bits (157), Expect = 1e-09, Method: Composition-based stats.
Identities = 17/127 (13%), Positives = 44/127 (35%), Gaps = 12/127 (9%)
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEM---------DSVIISRIVKGGAAEK 291
+++ +V + + + + +S+IV G A K
Sbjct 235 AAPPGGKGEETKSLTLVLHRDSGSLGFNIIGGRPSVDNHDGSSSEGIFVSKIVDSGPAAK 294
Query 292 SGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI---PSQQIKPPPAKETVI 348
G L D ++E+NG ++ ++ + + ++ P ++ PP++ ++
Sbjct 295 EGGLQIHDRIIEVNGRDLSRATHDQAVEAFKTAKEPIVVQVLRRTPRTKMFTPPSESQLV 354
Query 349 HVKAHFD 355
D
Sbjct 355 DTGTQTD 361
Score = 50.4 bits (119), Expect = 5e-05, Method: Composition-based stats.
Identities = 23/86 (27%), Positives = 35/86 (41%), Gaps = 9/86 (10%)
Query 262 ARDIPLGATV-----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
LG TV + + IS I A K G + EGD +++INGIE++ + E
Sbjct 426 NSQDKLGLTVCYRTDDEDDIGIYISEIDPNSIAAKDGRIREGDRIIQINGIEVQNR--EE 483
Query 317 VFDLL--SDMHGTLTFVLIPSQQIKP 340
LL + + P Q+
Sbjct 484 AVALLTSEENKNFSLLIARPELQLDE 509
>sp|Q5EBL8|PDZ11_HUMAN PDZ domain-containing protein 11 OS=Homo
sapiens OX=9606 GN=PDZD11 PE=1 SV=2
Length=140
Score = 60.1 bits (144), Expect = 2e-09, Method: Composition-based stats.
Identities = 21/113 (19%), Positives = 47/113 (42%), Gaps = 10/113 (9%)
Query 231 EMQLEP---ITDERV--YESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISR 282
+ P ERV + + + + ++K LG +R + IS+
Sbjct 17 AYENPPAWIPPHERVHHPDYNNELTQFLPRTITLKKPPGAQLGFNIRGGKASQLGIFISK 76
Query 283 IVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG-TLTFVLIP 334
++ A ++G L EGD+VL +N ++ + + ++ ++L ++ P
Sbjct 77 VIPDSDAHRAG-LQEGDQVLAVNDVDFQDIEHSKAVEILKTAREISMRVRFFP 128
>sp|Q9P202|WHRN_HUMAN Whirlin OS=Homo sapiens OX=9606 GN=WHRN
PE=1 SV=4
Length=907
Score = 65.1 bits (157), Expect = 2e-09, Method: Composition-based stats.
Identities = 24/96 (25%), Positives = 37/96 (39%), Gaps = 5/96 (5%)
Query 249 YGGETVKIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
G K V + LG T+R + + I+ + G AE SG L GD++LE+N
Sbjct 272 LQGGDEKKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAEGSG-LKVGDQILEVN 330
Query 306 GIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
G +E LL L + ++
Sbjct 331 GRSFLNILHDEAVRLLKSSRH-LILTVKDVGRLPHA 365
Score = 62.8 bits (151), Expect = 7e-09, Method: Composition-based stats.
Identities = 31/142 (22%), Positives = 54/142 (38%), Gaps = 19/142 (13%)
Query 205 GQELTALLNTPHIQALL------------LAHDKVAEQEMQLEPITDERVYE--SIGQYG 250
+ L LL++P + LL L D+ + + L T R G
Sbjct 75 VRTLRVLLDSPVKRRLLPMLRLVIPRSDQLLFDQYTAEGLYLPATTPYRQPAWGGPDSAG 134
Query 251 GETVKIVRIEKARD-IPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEING 306
V++V + +A+ LG ++R + + +S + G AEK G L GD++L +N
Sbjct 135 PGEVRLVSLRRAKAHEGLGFSIRGGSEHGVGIYVSLVEPGSLAEKEG-LRVGDQILRVND 193
Query 307 IEIRGKDVNEVFDLLSDMHGTL 328
+ E L +
Sbjct 194 KSLARVTHAEAVKALKGSKKLV 215
Score = 53.1 bits (126), Expect = 7e-06, Method: Composition-based stats.
Identities = 26/109 (24%), Positives = 52/109 (48%), Gaps = 13/109 (12%)
Query 226 KVAEQEMQLEPIT-DERVYESIGQYGG---ETVKIVRIEKARDIPLGATV------RNEM 275
V+ + + + +ER + + G T +VR++K+ LG + R +
Sbjct 782 SVSTKSRSSKELPRNERPTDGANKPPGLLEPTSTLVRVKKSAA-TLGIAIEGGANTRQPL 840
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
++ I +GG+A G L G +LE+NG+ +RGK+ E ++++
Sbjct 841 PRIVT--IQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARIIAEA 887
>sp|Q8TEW8|PAR3L_HUMAN Partitioning defective 3 homolog B OS=Homo
sapiens OX=9606 GN=PARD3B PE=1 SV=2
Length=1205
Score = 65.1 bits (157), Expect = 2e-09, Method: Composition-based stats.
Identities = 27/123 (22%), Positives = 49/123 (40%), Gaps = 13/123 (11%)
Query 230 QEMQLE-----PITDERVYESIGQYGGETVKI-VRIEKARDIPLGATVR------NEMDS 277
+ ++ P + KI + ++K + LG TV +
Sbjct 351 KSPRVPRLGGKPSSPSLSPLMGFGSNKNAKKIKIDLKKGPE-GLGFTVVTRDSSIHGPGP 409
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
+ + I+ GAA K G L GD +LE+NG ++ G+ E+ +L T L+ ++Q
Sbjct 410 IFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVIARQ 469
Query 338 IKP 340
Sbjct 470 EGH 472
Score = 52.4 bits (124), Expect = 1e-05, Method: Composition-based stats.
Identities = 31/161 (19%), Positives = 58/161 (36%), Gaps = 28/161 (17%)
Query 191 QEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYG 250
+E+ +L+ E L H +E++ EP E+ Q
Sbjct 447 EELVAMLRSTKQGETASLVIARQEGHFL----------PRELKGEPDCCALSLETSEQLT 496
Query 251 GETVKIVRIEKARDIPLGATVRNEMD-------SVIISRIVKGGAAEKSGLLHEGDEVLE 303
E + + + LG +++ + I I+ GGAA K G L D+++
Sbjct 497 FE----IPLNDSGSAGLGVSLKGNKSRETGTDLGIFIKSIIHGGAAFKDGRLRMNDQLIA 552
Query 304 INGIEIRGKDVNEVFDLLSDM-------HGTLTFVLIPSQQ 337
+NG + GK +E + L G + V++ +
Sbjct 553 VNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQLVILRRPE 593
Score = 45.8 bits (107), Expect = 0.002, Method: Composition-based stats.
Identities = 26/152 (17%), Positives = 53/152 (35%), Gaps = 18/152 (12%)
Query 194 QTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGET 253
H GQ L L P L + + + +L + S +
Sbjct 149 ADTQPSASHPGGQSLK--LVVPDSTQNLEDREVLNGVQTELLTSPRTKDTLS------DM 200
Query 254 VKIVRIEKARDIPLGA-------TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEING 306
+ V I PLG ++ + + I I +++ GL HE + +++IN
Sbjct 201 TRTVEIS-GEGGPLGIHVVPFFSSLSGRILGLFIRGIEDNSRSKREGLFHENECIVKINN 259
Query 307 IEIRGKDVNEVFDLLSDM--HGTLTFVLIPSQ 336
+++ K + D+ ++ ++P Q
Sbjct 260 VDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQ 291
>sp|Q9QYX7|PCLO_MOUSE Protein piccolo OS=Mus musculus OX=10090
GN=Pclo PE=1 SV=4
Length=5068
Score = 65.1 bits (157), Expect = 2e-09, Method: Composition-based stats.
Identities = 25/77 (32%), Positives = 39/77 (51%), Gaps = 4/77 (5%)
Query 257 VRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
+RI ++IP + I++I+ GG+AE SG L EG +VLE NGI + K E
Sbjct 4443 IRIVGGKEIP----GHSGEIGAYIAKILPGGSAEHSGKLIEGMQVLEWNGIPLTSKTYEE 4498
Query 317 VFDLLSDMHGTLTFVLI 333
V +++ G +
Sbjct 4499 VQSIINQQSGEAEICVR 4515
>sp|Q6NXB2|PDZ11_DANRE PDZ domain-containing protein 11 OS=Danio
rerio OX=7955 GN=pdzd11 PE=2 SV=1
Length=142
Score = 59.7 bits (143), Expect = 2e-09, Method: Composition-based stats.
Identities = 21/107 (20%), Positives = 44/107 (41%), Gaps = 9/107 (8%)
Query 231 EMQLEP---ITDERV--YESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISR 282
+ P ER+ + + + + ++K LG +R + IS+
Sbjct 19 SYENPPAWIPPQERIHHPDYNNELAQFLPRTIVLKKPPGAQLGFNIRGGKASQLGIFISK 78
Query 283 IVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLT 329
+V A ++G L EGD+VL +N ++ + + + ++L L
Sbjct 79 VVPDSDAHRAG-LQEGDQVLSVNEVDFQDIEHSRAVEILKTAREILM 124
>sp|Q9BXL7|CAR11_HUMAN Caspase recruitment domain-containing protein
11 OS=Homo sapiens OX=9606 GN=CARD11 PE=1 SV=3
Length=1154
Score = 64.7 bits (156), Expect = 3e-09, Method: Composition-based stats.
Identities = 83/514 (16%), Positives = 154/514 (30%), Gaps = 92/514 (18%)
Query 236 PITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLL 295
P + G +V+ + + + + G AEK+G L
Sbjct 648 PFRPSVTSVGHVRGPGPSVQHTTLNGDSLTSQLTLLGGNARGSFVHSVKPGSLAEKAG-L 706
Query 296 HEGDEVL--------EINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAK--- 344
EG ++L E + + E + G +T + + K
Sbjct 707 REGHQLLLLEGCIRGERQSVPLDTCTKEEAHWTIQRCSGPVTLHYKVNHEGYRKLVKDME 766
Query 345 ------ETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVIS---QEDPNWWQAYRE 395
+++ + + D +S + D++HV Q+ W A +
Sbjct 767 DGLITSGDSFYIRLNLNISSQLDACT------MSLKCDDVVHVRDTMYQDRHEWLCARVD 820
Query 396 GDEDNQPLAGLVPGKSFQQQ----REAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLY- 450
D+ G +P S QQ + +E + + A +N + ++ L
Sbjct 821 PFTDHDLDMGTIPSYSRAQQLLLVKLQRLMHRGSREEVDGTHHTLRALRNTLQPEEALST 880
Query 451 --------NANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIG-PQNC----------- 490
+ + + + Y + + +R I+ G P
Sbjct 881 SDPRVSPRLSRASFLFGQLLQFVSRSENKYKRMNSNERVRIISGSPLGSLARSSLDATKL 940
Query 491 --------------GQN------ELRQRLM--NKEKDRFASAVPHTTRSRRDQEVAGRDY 528
G+N L + + F V T +R G
Sbjct 941 LTEKQEELDPESELGKNLSLIPYSLVRAFYCERRRPVLFTPTVLAKTLVQRLLNSGGAME 1000
Query 529 H------FVSRQAFEADIAAGKFIEHGEFEKN-LYGTSIDSVRQVINSGKICLLSLRTQS 581
V+R F I E N + ++ V K CLL
Sbjct 1001 FTICKSDIVTRDEFLRRQKTETIIYSREKNPNAFECIAPANIEAVAAKNKHCLLEAGIGC 1060
Query 582 LKTLRNSDLKPYIIFIA--PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYF 639
+ L S++ P ++FI + +R R LL + P+ EE + + +E E
Sbjct 1061 TRDLIKSNIYPIVLFIRVCEKNIKRFRKLLPR----PETEEEFLRVCRLKEKELEALPCL 1116
Query 640 DTAIVNSDLDKAYQELLRL----INKLDTEPQWV 669
A V D+ + +ELLR+ I + + WV
Sbjct 1117 -YATVEPDMWGSVEELLRVVKDKIGEEQRKTIWV 1149
>sp|Q6ZMN7|PZRN4_HUMAN PDZ domain-containing RING finger protein
4 OS=Homo sapiens OX=9606 GN=PDZRN4 PE=1 SV=3
Length=1036
Score = 64.3 bits (155), Expect = 3e-09, Method: Composition-based stats.
Identities = 11/72 (15%), Positives = 32/72 (44%), Gaps = 0/72 (0%)
Query 272 RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV 331
+ + +S+I++ G A+++ L D+++E+NG ++ E + + +
Sbjct 250 GTSTEGIYVSKILENGPADRADGLEIHDKIMEVNGKDLSKATHEEAVEAFRNAKEPIVVQ 309
Query 332 LIPSQQIKPPPA 343
++ + P
Sbjct 310 VLRRTPLSRPAY 321
Score = 55.4 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 29/126 (23%), Positives = 53/126 (42%), Gaps = 14/126 (11%)
Query 222 LAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV-----RNEMD 276
+ H+ + E + + + +Y E V++ R+ + LG TV E
Sbjct 374 MEHEFYEDNEY-ISSLPADADRTEDFEY--EEVELCRV--SSQEKLGLTVCYRTDDEEDT 428
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM--HGTLTFVLIP 334
+ +S + A K G + EGD +L+ING +++ + E LLS+ + V P
Sbjct 429 GIYVSEVDPNSIAAKDGRIREGDRILQINGEDVQNR--EEAVALLSNDECKRIVLLVARP 486
Query 335 SQQIKP 340
Q+
Sbjct 487 EIQLDE 492
>sp|P54288|CACB2_RABIT Voltage-dependent L-type calcium channel
subunit beta-2 OS=Oryctolagus cuniculus OX=9986 GN=CACNB2
PE=1 SV=1
Length=632
Score = 63.9 bits (154), Expect = 3e-09, Method: Composition-based stats.
Identities = 57/369 (15%), Positives = 114/369 (31%), Gaps = 57/369 (15%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
Q++ K V+ + Y + + VP + +SF+ D LHV + + +WW
Sbjct 76 QAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRL 135
Query 395 EGDEDNQPLAGLVPGK------SFQ-QQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKK 447
G +P Q +QR + S L + +K
Sbjct 136 V---KEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTP 192
Query 448 VLYN----------------ANKNDDYDNEEILTYEEMSLYHQPANRK------------ 479
AN + +T P +K
Sbjct 193 PSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPS 252
Query 480 -RPIILIGPQNCG---QNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
RP++L+GP G + +++ L + K RF + T + + S+ A
Sbjct 253 MRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHA 312
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKI---CLLSLR-TQSLKTLRNSDLK 591
+ E + + ++ + +L L + L
Sbjct 313 IIERSNTRSSL--AEVQ--------SEIERIFELARTLQLVVLDADTINHPAQLSKTSLA 362
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
P ++++ S + L+ L+ GK + + L + ++ Q FD + + L+ A
Sbjct 363 PIVVYVKISSPKVLQRLIKSRGK-SQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDA 421
Query 652 YQELLRLIN 660
+ L +
Sbjct 422 CEHLADYLE 430
>sp|Q91XL2|LNX2_MOUSE Ligand of Numb protein X 2 OS=Mus musculus
OX=10090 GN=Lnx2 PE=1 SV=2
Length=687
Score = 63.9 bits (154), Expect = 3e-09, Method: Composition-based stats.
Identities = 18/91 (20%), Positives = 39/91 (43%), Gaps = 2/91 (2%)
Query 252 ETVKIVRIEKARDIPLGATV--RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
E +++ ++ LG + R + V I +++GG A + G L+ D VL ING ++
Sbjct 335 EVFQVLLHKRDSTEQLGIKLVRRTDEPGVFILDLLEGGLAAQDGRLNSNDRVLAINGHDL 394
Query 310 RGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
+ ++ + + + +P
Sbjct 395 KHGTPELAAQIIQASGERVNLTIARPGKPQP 425
Score = 55.8 bits (133), Expect = 9e-07, Method: Composition-based stats.
Identities = 29/149 (19%), Positives = 52/149 (35%), Gaps = 17/149 (11%)
Query 255 KIVRIEKARDIPLGATVRNEMD------SVIISRIVKGGAAEKSGLLHEGDEVLEINGIE 308
K + ++K LG TV + ++ + G + G + GD +L INGI+
Sbjct 464 KHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVPPHGCLARDGRIKRGDVLLNINGID 523
Query 309 IRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPC-- 366
+ +E +L + +L + A + + F + D + P
Sbjct 524 LTNLSHSEAVAMLKASAASPAVILKALEVQIAEEAAQATEEQPSAFSENEYDASWSPSWV 583
Query 367 RELGLSFQKGDILH-----VISQEDPNWW 390
LGL LH V+ + W
Sbjct 584 MWLGLP----SALHSCHDIVLRRSYLGSW 608
Score = 55.1 bits (131), Expect = 2e-06, Method: Composition-based stats.
Identities = 16/76 (21%), Positives = 34/76 (45%), Gaps = 2/76 (3%)
Query 264 DIPLGATVRNEMD--SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ + NE +++I + + G + G L GD++L++N +I N +L
Sbjct 243 QLGISIVGGNETPLINIVIQEVYRDGVIARDGRLLAGDQILQVNNYDISNVSHNHARAVL 302
Query 322 SDMHGTLTFVLIPSQQ 337
S TL ++ ++
Sbjct 303 SQPCSTLQLTVLRERR 318
Score = 50.8 bits (120), Expect = 4e-05, Method: Composition-based stats.
Identities = 15/61 (25%), Positives = 26/61 (43%), Gaps = 0/61 (0%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ I IV G A G L GD ++ +NG+ G + + +L + +T +
Sbjct 620 HTNQPFFIKTIVLGTPAYYDGRLKCGDMIVAVNGLSTVGMSHSALVPMLKEQRNKVTLTV 679
Query 333 I 333
I
Sbjct 680 I 680
>sp|O35430|APBA1_RAT Amyloid-beta A4 precursor protein-binding
family A member 1 OS=Rattus norvegicus OX=10116 GN=Apba1 PE=1
SV=1
Length=839
Score = 63.9 bits (154), Expect = 4e-09, Method: Composition-based stats.
Identities = 46/220 (21%), Positives = 88/220 (40%), Gaps = 13/220 (6%)
Query 126 DLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISN 185
DLF S + I+ D+Q L + D N + + + +
Sbjct 520 DLFISTQRIKVLNADTQEPMMDHPLRTISYIADIGNIVVLMARRRMPRSNSQENVEASHP 579
Query 186 AQDLAQEVQTVLKPVHHKEGQELTALLNTPH---IQALLLAH----DKVAEQEM-QLEPI 237
+QD ++ + + ++ Q + + Q L A+ + ++++E L
Sbjct 580 SQDAKRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDLLNT 639
Query 238 TDERVYESIGQYGGETVKIVRIEKARDIPLGATV-----RNEMDSVIISRIVKGGAAEKS 292
D + I E K V IEK + LG + + + +VII+ ++ GG AEKS
Sbjct 640 QDMYNDDLIHFSKSENCKDVFIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKS 699
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
G L+ GD+++ ING + G ++ ++ + L
Sbjct 700 GKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKL 739
Score = 57.8 bits (138), Expect = 3e-07, Method: Composition-based stats.
Identities = 19/84 (23%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
L + + + II +++GG AE+ G + G ++EING + ++ +LS+ G
Sbjct 757 LRYQLGFSVQNGIICSLMRGGIAER-GGVRVGHRIIEINGQSVVATPHEKIVHILSNAVG 815
Query 327 TLTFVLIPSQQIKPPPAKETVIHV 350
+ +P+ + A+E +++
Sbjct 816 EIHMKTMPAAMYRLLTAQEQPVYI 839
>sp|Q8TBB1|LNX1_HUMAN E3 ubiquitin-protein ligase LNX OS=Homo
sapiens OX=9606 GN=LNX1 PE=1 SV=1
Length=728
Score = 63.5 bits (153), Expect = 4e-09, Method: Composition-based stats.
Identities = 20/93 (22%), Positives = 39/93 (42%), Gaps = 6/93 (6%)
Query 255 KIVRIEKARDIPLGATVRNEMD------SVIISRIVKGGAAEKSGLLHEGDEVLEINGIE 308
K+V I+K LG TV + + + GG + G + GD +L ++G+E
Sbjct 506 KVVNIQKDPGESLGMTVAGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVDGVE 565
Query 309 IRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
+ +E LL ++ + ++ +P
Sbjct 566 LTEVSRSEAVALLKRTSSSIVLKALEVKEYEPQ 598
Score = 61.6 bits (148), Expect = 2e-08, Method: Composition-based stats.
Identities = 20/92 (22%), Positives = 40/92 (43%), Gaps = 2/92 (2%)
Query 252 ETVKIVRIEKARDIPLGATV--RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
++ ++ + + + LG + + + V I ++ GG A + G L E D VL ING ++
Sbjct 378 DSFHVILNKSSPEEQLGIKLVRKVDEPGVFIFNVLDGGVAYRHGQLEENDRVLAINGHDL 437
Query 310 RGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
R L+ + V+ + + P
Sbjct 438 RYGSPESAAHLIQASERRVHLVVSRQVRQRSP 469
Score = 60.1 bits (144), Expect = 4e-08, Method: Composition-based stats.
Identities = 27/149 (18%), Positives = 59/149 (40%), Gaps = 4/149 (3%)
Query 195 TVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITD--ERVYESIGQYGGE 252
+ ++ K+ ++L + + H + + + R+Y I
Sbjct 214 STIRSRSFKKINRALSVLRRTKSGSAVANHADQGRENSENTTAPEVFPRLYHLIPDGEIT 273
Query 253 TVKIVRIEKARDIPLGATVRNEMD--SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
++KI R++ + + + +E +II I + G + G L GD +L++NG++I
Sbjct 274 SIKINRVDPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDIS 333
Query 311 GKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
N LL L ++ Q+ +
Sbjct 334 NVPHNYAVRLLRQPCQVLWLTVMREQKFR 362
Score = 52.0 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 26/157 (17%), Positives = 49/157 (31%), Gaps = 19/157 (12%)
Query 196 VLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGET-- 253
L V E L ++ + L + +++ D + +
Sbjct 565 ELTEVSRSEAVALLKRTSSSIVLKALEVKEYEPQEDCSSPAALDSNHNMAPPSDWSPSWV 624
Query 254 -----------VKIVRIEKARDIPLGATV------RNEMDSVIISRIVKGGAAEKSGLLH 296
K + + + LG + N I IV+G A G +
Sbjct 625 MWLELPRCLYNCKDIVLRRNTAGSLGFCIVGGYEEYNGNKPFFIKSIVEGTPAYNDGRIR 684
Query 297 EGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
GD +L +NG G + LL ++ G +T ++
Sbjct 685 CGDILLAVNGRSTSGMIHACLARLLKELKGRITLTIV 721
>sp|Q69ZS0|PZRN3_MOUSE E3 ubiquitin-protein ligase PDZRN3 OS=Mus
musculus OX=10090 GN=Pdzrn3 PE=1 SV=3
Length=1063
Score = 63.9 bits (154), Expect = 4e-09, Method: Composition-based stats.
Identities = 16/127 (13%), Positives = 43/127 (34%), Gaps = 12/127 (9%)
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNE---------MDSVIISRIVKGGAAEK 291
+++ +V + + + + +S+IV G A K
Sbjct 235 AAPPGGKGEETKSLTLVLHRDSGSLGFNIIGGRPCVDNQDGSSSEGIFVSKIVDSGPAAK 294
Query 292 SGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI---PSQQIKPPPAKETVI 348
G L D ++E+NG ++ ++ + + ++ P ++ P ++ ++
Sbjct 295 EGGLQIHDRIIEVNGKDLSRATHDQAVEAFKTAKEPIVVQVLRRTPRTKMFTPASESQLV 354
Query 349 HVKAHFD 355
D
Sbjct 355 DTGTQTD 361
Score = 52.8 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 28/135 (21%), Positives = 51/135 (38%), Gaps = 9/135 (7%)
Query 213 NTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV- 271
+ P + LL + A + +++ + + E ++ LG TV
Sbjct 377 SPPVLDPYLLPEEHPASHDYYDPNDYMGDIHQDMDREELELEEVGLYRMNSQDKLGLTVC 436
Query 272 ----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL--SDMH 325
+ + IS I A K G + EGD +++INGIE++ + E LL +
Sbjct 437 YRTDDEDDIGIYISEIDPNSIAAKDGRIREGDRIIQINGIEVQNR--EEAVALLTSEENK 494
Query 326 GTLTFVLIPSQQIKP 340
+ P Q+
Sbjct 495 NFSLLIARPELQLDE 509
>sp|Q80VW5|WHRN_MOUSE Whirlin OS=Mus musculus OX=10090 GN=Whrn
PE=1 SV=3
Length=918
Score = 63.5 bits (153), Expect = 4e-09, Method: Composition-based stats.
Identities = 23/90 (26%), Positives = 36/90 (40%), Gaps = 5/90 (6%)
Query 255 KIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
K V + LG T+R + + I+ + G AE SG L GD++LE+NG
Sbjct 279 KKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAESSG-LKVGDQILEVNGRSFLN 337
Query 312 KDVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
+E LL L + ++
Sbjct 338 ILHDEAVKLLKSSRH-LILTVKDVGRLPHA 366
Score = 62.0 bits (149), Expect = 1e-08, Method: Composition-based stats.
Identities = 31/142 (22%), Positives = 55/142 (39%), Gaps = 19/142 (13%)
Query 205 GQELTALLNTPHIQALL------------LAHDKVAEQEMQLEPITDERVYE--SIGQYG 250
+ L LL++P + LL L D+ + + L T R + G
Sbjct 76 VRTLRVLLDSPVKRRLLPMLRLVIPRSDQLLFDQYTAEGLYLPATTPYRQPAWAAPDGAG 135
Query 251 GETVKIVRIEKARD-IPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEING 306
V++V + +A+ LG ++R + + +S + G AEK G L GD++L +N
Sbjct 136 PGEVRLVSLRRAKAHEGLGFSIRGGSEHGVGIYVSLVEPGSLAEKEG-LRVGDQILRVND 194
Query 307 IEIRGKDVNEVFDLLSDMHGTL 328
+ E L +
Sbjct 195 KSLARVTHAEAVKALKGSKKLV 216
Score = 52.8 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 34/181 (19%), Positives = 65/181 (36%), Gaps = 14/181 (8%)
Query 152 QLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQ--EVQTVLKPVHHKEGQELT 209
V ++H + P A L+Q + L + E T
Sbjct 724 DAVGANQHFVLVEVHRPDSEPDVNEVRALPQTRTASTLSQLSDSGQTLSEDSGVDAGE-T 782
Query 210 ALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGA 269
+ + A +K +++ + E + T +VR+ K+ LG
Sbjct 783 EASTSGRGRQTASAKNKNGKEQPRTERTAEGA--NKPPGLLEPTSTLVRVRKSAA-TLGI 839
Query 270 TV------RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD 323
+ R + ++ I +GG+A G L G +LE+NG +RGK+ E ++++
Sbjct 840 AIEGGANTRQPLPRIVT--IQRGGSAHNCGQLKVGHVILEVNGQTLRGKEHKEAARIIAE 897
Query 324 M 324
Sbjct 898 A 898
>sp|P29074|PTN4_HUMAN Tyrosine-protein phosphatase non-receptor
type 4 OS=Homo sapiens OX=9606 GN=PTPN4 PE=1 SV=1
Length=926
Score = 63.5 bits (153), Expect = 5e-09, Method: Composition-based stats.
Identities = 33/156 (21%), Positives = 61/156 (39%), Gaps = 16/156 (10%)
Query 216 HIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEM 275
H Q L +H + + ++ G + + ++R++ + G V+
Sbjct 482 HSQQDLESH---INETFDIPSSPEK--PTPNGGIPHDNLVLIRMKPDENGRFGFNVKGGY 536
Query 276 D---SVIISRIVKGGAAEKS-GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM----HGT 327
D VI+SR+ G A+ L+EGD+V+ ING +I ++V + G
Sbjct 537 DQKMPVIVSRVAPGTPADLCVPRLNEGDQVVLINGRDIAEHTHDQVVLFIKASCERHSGE 596
Query 328 LTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPY 363
L ++ P+ E + + F Y P P
Sbjct 597 LMLLVRPNAVYDVV---EEKLENEPDFQYIPEKAPL 629
>sp|Q9MZL5|CACB2_BOVIN Voltage-dependent L-type calcium channel
subunit beta-2 OS=Bos taurus OX=9913 GN=CACNB2 PE=2 SV=1
Length=603
Score = 63.2 bits (152), Expect = 5e-09, Method: Composition-based stats.
Identities = 63/414 (15%), Positives = 125/414 (30%), Gaps = 59/414 (14%)
Query 292 SGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV--IH 349
GL+H + + ++ L + + Q + AK
Sbjct 4 CGLVHRRRARVSYGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFA 63
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
V+ + Y + + VP + +SF+ D LHV + + +WW G +P
Sbjct 64 VRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLV---KEGCEIGFIPS 120
Query 410 K------SFQ-QQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYN----------- 451
Q +QR + S L + +K
Sbjct 121 PVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAE 180
Query 452 -----ANKNDDYDNEEILTYEEMSLYHQPANRK-------------RPIILIGPQNCG-- 491
AN + +T P +K RP++L+GP G
Sbjct 181 DNDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYE 240
Query 492 -QNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGE 550
+ +++ L + K RF + T + + S+ A + E
Sbjct 241 VTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSL--AE 298
Query 551 FEKNLYGTSIDSVRQVINSGKI---CLLSLR-TQSLKTLRNSDLKPYIIFIAPPSQERLR 606
+ + ++ + +L L + L P I+++ S + L+
Sbjct 299 VQ--------SEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQ 350
Query 607 ALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 660
L+ GK + + L + ++ Q FD + + L+ A + L +
Sbjct 351 RLIKSRGK-SQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE 403
>sp|O70263|LNX1_MOUSE E3 ubiquitin-protein ligase LNX OS=Mus musculus
OX=10090 GN=Lnx1 PE=1 SV=1
Length=728
Score = 63.2 bits (152), Expect = 6e-09, Method: Composition-based stats.
Identities = 23/98 (23%), Positives = 43/98 (44%), Gaps = 3/98 (3%)
Query 252 ETVKIVRIEKARDIPLGATV--RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
++ ++ + + + LG + R + V I ++ GG A++ G L E D VL ING ++
Sbjct 382 DSFHVILNKSSPEEQLGIKLVRRVDEPGVFIFNVLNGGVADRHGQLEENDRVLAINGHDL 441
Query 310 RGKDVNEVFDLLSDMHGTLTFVL-IPSQQIKPPPAKET 346
R L+ + V+ +Q P +E
Sbjct 442 RFGSPESAAHLIQASERRVHLVVSRQVRQSSPDIFQEA 479
Score = 63.2 bits (152), Expect = 6e-09, Method: Composition-based stats.
Identities = 19/93 (20%), Positives = 36/93 (39%), Gaps = 6/93 (6%)
Query 255 KIVRIEKARDIPLGATVRNEMD------SVIISRIVKGGAAEKSGLLHEGDEVLEINGIE 308
K+V + K LG TV + + + GG + G + GD +L +NGIE
Sbjct 507 KVVSVWKDPSESLGMTVGGGASHREWDLPIYVISVEPGGVISRDGRIKTGDILLNVNGIE 566
Query 309 IRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
+ E +L ++ + ++ +
Sbjct 567 LTEVSRTEAVAILKSAPSSVVLKALEVKEQEAQ 599
Score = 62.0 bits (149), Expect = 1e-08, Method: Composition-based stats.
Identities = 34/199 (17%), Positives = 69/199 (35%), Gaps = 27/199 (14%)
Query 195 TVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGE-- 252
+ ++ K+ + L +++ H + + + GE
Sbjct 218 STMRSRSFKKINRALSALRRTKSGSVVANHVDQGRDNSENTTVPEVFPRLFHLIPDGEIT 277
Query 253 TVKIVRIEKARDIPLGATVRNEMD--SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
++KI R + + + + +E +II I + G + G L GD +L++NG++I
Sbjct 278 SIKINRADPSESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMDIS 337
Query 311 GKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELG 370
N LL L ++ +E +++ D Y P
Sbjct 338 NVPHNYAVRLLRQPCQVLRLTVL----------REQKFRSRSNAH---VPDSYGP----- 379
Query 371 LSFQKGDILHVI-SQEDPN 388
+ D HVI ++ P
Sbjct 380 ----RDDSFHVILNKSSPE 394
Score = 50.4 bits (119), Expect = 5e-05, Method: Composition-based stats.
Identities = 19/84 (23%), Positives = 33/84 (39%), Gaps = 6/84 (7%)
Query 255 KIVRIEKARDIPLGATVRNEMD------SVIISRIVKGGAAEKSGLLHEGDEVLEINGIE 308
K V + + LG + + I IV+G A G + GD +L +NG
Sbjct 637 KDVILRRNTAGSLGFCIVGGYEEYSGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRS 696
Query 309 IRGKDVNEVFDLLSDMHGTLTFVL 332
G + +L ++ G +T +
Sbjct 697 TSGMIHACLARMLKELKGRITLTI 720
>sp|P68907|PZRN3_RAT E3 ubiquitin-protein ligase PDZRN3 OS=Rattus
norvegicus OX=10116 GN=Pdzrn3 PE=1 SV=1
Length=1062
Score = 63.2 bits (152), Expect = 6e-09, Method: Composition-based stats.
Identities = 16/116 (14%), Positives = 43/116 (37%), Gaps = 12/116 (10%)
Query 252 ETVKIVRIEKARDIPLGATVRNE---------MDSVIISRIVKGGAAEKSGLLHEGDEVL 302
+++ +V + + + + +S+IV G A K G L D ++
Sbjct 245 KSLTLVLHRDSGSLGFNIIGGRPCVDNQDGSSSEGIFVSKIVDSGPAAKEGGLQIHDRII 304
Query 303 EINGIEIRGKDVNEVFDLLSDMHGTLTFVLI---PSQQIKPPPAKETVIHVKAHFD 355
E+NG ++ ++ + + ++ P ++ P ++ ++ D
Sbjct 305 EVNGKDLSRATHDQAVEAFKTAKEPIVVQVLRRTPRTKMFTPASESQLVDTGTQTD 360
Score = 50.4 bits (119), Expect = 5e-05, Method: Composition-based stats.
Identities = 23/86 (27%), Positives = 35/86 (41%), Gaps = 9/86 (10%)
Query 262 ARDIPLGATV-----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
LG TV + + IS I A K G + EGD +++INGIE++ + E
Sbjct 425 NSQDKLGLTVCYRTDDEDDIGIYISEIDPNSIAAKDGRIREGDRIIQINGIEVQNR--EE 482
Query 317 VFDLL--SDMHGTLTFVLIPSQQIKP 340
LL + + P Q+
Sbjct 483 AVALLTSEENKNFSLLIARPELQLDE 508
>sp|Q08289|CACB2_HUMAN Voltage-dependent L-type calcium channel
subunit beta-2 OS=Homo sapiens OX=9606 GN=CACNB2 PE=1 SV=3
Length=660
Score = 62.8 bits (151), Expect = 7e-09, Method: Composition-based stats.
Identities = 58/369 (16%), Positives = 114/369 (31%), Gaps = 57/369 (15%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
Q++ K V+ + Y + + VP + +SF+ D LHV + + +WW
Sbjct 104 QAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRL 163
Query 395 EGDEDNQPLAGLVPGK------SFQ-QQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKK 447
G +P Q +QR + S L + +K
Sbjct 164 V---KEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTP 220
Query 448 VLYN----------------ANKNDDYDNEEILTYEEMSLYHQPANRK------------ 479
AN + +T P +K
Sbjct 221 PSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPS 280
Query 480 -RPIILIGPQNCG---QNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
RP++L+GP G + +++ L + K RF + T + + S+ A
Sbjct 281 MRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHA 340
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKI---CLLSLR-TQSLKTLRNSDLK 591
+ E + + ++ + +L L + L
Sbjct 341 IIERSNTRSSL--AEVQ--------SEIERIFELARTLQLVVLDADTINHPAQLSKTSLA 390
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
P I+++ S + L+ L+ GK + + L + ++ Q FD + + L+ A
Sbjct 391 PIIVYVKISSPKVLQRLIKSRGK-SQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDA 449
Query 652 YQELLRLIN 660
+ L +
Sbjct 450 CEHLADYLE 458
>sp|O19132|NOS1_RABIT Nitric oxide synthase 1 OS=Oryctolagus cuniculus
OX=9986 GN=NOS1 PE=2 SV=1
Length=1435
Score = 63.2 bits (152), Expect = 7e-09, Method: Composition-based stats.
Identities = 47/208 (23%), Positives = 74/208 (36%), Gaps = 26/208 (13%)
Query 248 QYGGETVKIVRIEKARDIPLGATVRNEM--DSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
Q V VR+ K + LG V+ + VIIS +++GGAAE+SGL+ GD +L +N
Sbjct 9 QQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVN 68
Query 306 GIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVP 365
G + + ++L + VLI ET F D +
Sbjct 69 GRPLVDLSYDSALEVLRGVASETHVVLILRGPEGFTTNLETT------FTGDGTPKTIRV 122
Query 366 CRELGLSFQKGDILH------------VISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
+ LG + D+ H V P W + + + AG S
Sbjct 123 TQPLGAPTKAVDLSHQPPSAGKEQPRPVDGAAGPGSW---PQPTQGHGQEAG---SPSRA 176
Query 414 QQREAMKQTIEEDKEPEKSGKLWCAKKN 441
+ + K+ +G KN
Sbjct 177 NGLAPRTSSQDPAKKSGWAGLQGSGDKN 204
>sp|Q8MJ50|OSTF1_BOVIN Osteoclast-stimulating factor 1 OS=Bos
taurus OX=9913 GN=OSTF1 PE=2 SV=1
Length=214
Score = 59.7 bits (143), Expect = 8e-09, Method: Composition-based stats.
Identities = 18/80 (23%), Positives = 35/80 (44%), Gaps = 13/80 (16%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
+A + ++P L F++GDI+++ D NWW+ +G GL+P
Sbjct 18 RALYTFEPRTPDE-------LYFEEGDIIYITDMSDTNWWKGTCKG------RTGLIPSN 64
Query 411 SFQQQREAMKQTIEEDKEPE 430
+Q E++ + E +
Sbjct 65 YVAEQAESIDNPLHEAAKRG 84
>sp|O15018|PDZD2_HUMAN PDZ domain-containing protein 2 OS=Homo
sapiens OX=9606 GN=PDZD2 PE=1 SV=4
Length=2839
Score = 63.2 bits (152), Expect = 9e-09, Method: Composition-based stats.
Identities = 23/93 (25%), Positives = 43/93 (46%), Gaps = 6/93 (6%)
Query 254 VKIVRIEKARDIPLGATVRNEMD------SVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
+ I+ + K + LG ++ D + + I G+A + G L EGDE+L++NGI
Sbjct 584 ISIIGLYKEKGKGLGFSIAGGRDCIRGQMGIFVKTIFPNGSAAEDGRLKEGDEILDVNGI 643
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
I+G E + L + + ++ + P
Sbjct 644 PIKGLTFQEAIHTFKQIRSGLFVLTVRTKLVSP 676
Score = 62.8 bits (151), Expect = 9e-09, Method: Composition-based stats.
Identities = 21/104 (20%), Positives = 46/104 (44%), Gaps = 4/104 (4%)
Query 248 QYGGETVKIVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLE 303
+ G K+ ++++ + + + +++++++ +GGAA + G L GDE+L
Sbjct 327 EEVGRIWKMELLKESDGLGIQVSGGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDELLV 386
Query 304 INGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV 347
ING + G E +L G + V+ + + T
Sbjct 387 INGHLLVGLSHEEAVAILRSATGMVQLVVASKENSAEDLLRLTS 430
Score = 55.4 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 25/136 (18%), Positives = 51/136 (38%), Gaps = 13/136 (10%)
Query 250 GGETVKIVR---IEKARDIPLGA-----TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEV 301
G +IV + K + LG + N + I + G A+ L GD++
Sbjct 719 PGPKDRIVMEVTLNKEPRVGLGIGACCLALENSPPGIYIHSLAPGSVAKMESNLSRGDQI 778
Query 302 LEINGIEIRGKDVNEVFDLLSD-MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
LE+N + +R +++V +LS G + V+ K + + ++ +
Sbjct 779 LEVNSVNVRHAALSKVHAILSKCPPGPVRLVIGRHPNPKVSEQEMDEVIARSTYQESKEA 838
Query 361 DP----YVPCRELGLS 372
+ P + L+
Sbjct 839 NSSPGLGTPLKSPSLA 854
Score = 55.1 bits (131), Expect = 2e-06, Method: Composition-based stats.
Identities = 45/252 (18%), Positives = 90/252 (36%), Gaps = 39/252 (15%)
Query 122 LEIEDLFSSLKH-------IQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMN 174
++ + SS+ IQ S+++ED+ ++ L + + F + V
Sbjct 2588 QRLQSVLSSVGSKSTILTLIQEAKAQSENEEDVCFIV-LNRKEGSGLGFSVAGGTDV--E 2644
Query 175 KASPPFPLISNAQDLAQEVQ----TVLKPVHHKEGQELTA--LLNTPHIQALLLAHDKVA 228
S + + +QE L V+ L +L H L V
Sbjct 2645 PKSITVHRVFSQGAASQEGTMNRGDFLLSVNGASLAGLAHGNVLKVLHQAQLHKDALVVI 2704
Query 229 EQEMQLEPITDERVYESIGQYGGETVKIVRIEKA-----------------RDIPLGATV 271
++ M + + + G + K + +E LG ++
Sbjct 2705 KKGMDQPRPSARQEPPTANGKGLLSRKTIPLEPGIGRSVAVHDALCVEVLKTSAGLGLSL 2764
Query 272 RNEM------DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMH 325
++I R+ KGGAAE++G++ GDE+L ING + G + ++++ +
Sbjct 2765 DGGKSSVTGDGPLVIKRVYKGGAAEQAGIIEAGDEILAINGKPLVGLMHFDAWNIMKSVP 2824
Query 326 GTLTFVLIPSQQ 337
+LI +
Sbjct 2825 EGPVQLLIRKHR 2836
>sp|Q810W9|WHRN_RAT Whirlin OS=Rattus norvegicus OX=10116 GN=Whrn
PE=1 SV=1
Length=920
Score = 62.8 bits (151), Expect = 9e-09, Method: Composition-based stats.
Identities = 23/90 (26%), Positives = 36/90 (40%), Gaps = 5/90 (6%)
Query 255 KIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
K V + LG T+R + + I+ + G AE SG L GD++LE+NG
Sbjct 277 KKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAESSG-LKVGDQILEVNGRSFLS 335
Query 312 KDVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
+E LL L + ++
Sbjct 336 ILHDEAVKLLKSSRH-LILTVKDVGRLPHA 364
Score = 62.4 bits (150), Expect = 1e-08, Method: Composition-based stats.
Identities = 31/142 (22%), Positives = 55/142 (39%), Gaps = 19/142 (13%)
Query 205 GQELTALLNTPHIQALL------------LAHDKVAEQEMQLEPITDERVYE--SIGQYG 250
+ L LL++P + LL L D+ + + L T R + G
Sbjct 76 VRTLRVLLDSPVKRRLLPMLRLVIPRSDQLLFDQYTAEGLYLPATTPYRQPAWAAPDGAG 135
Query 251 GETVKIVRIEKARD-IPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEING 306
V++V + +A+ LG ++R + + +S + G AEK G L GD++L +N
Sbjct 136 PGEVRLVSLRRAKAHEGLGFSIRGGSEHGVGIYVSLVEPGSLAEKEG-LRVGDQILRVND 194
Query 307 IEIRGKDVNEVFDLLSDMHGTL 328
+ E L +
Sbjct 195 KSLARVTHAEAVKALKGSKKLV 216
Score = 50.8 bits (120), Expect = 4e-05, Method: Composition-based stats.
Identities = 25/97 (26%), Positives = 44/97 (45%), Gaps = 12/97 (12%)
Query 237 ITDERVYESIGQYGG---ETVKIVRIEKARDIPLGATV------RNEMDSVIISRIVKGG 287
ER E + G T ++R+ K+ LG + R + ++ I +GG
Sbjct 807 PQTERTTEGANKPPGLLEPTSTLIRVRKSAA-TLGIAIEGGANTRQPLPRIVT--IQRGG 863
Query 288 AAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
+A G L G +LE+NG +RGK+ E ++++
Sbjct 864 SAHNCGQLKVGHVILEVNGQTLRGKEHREAARVIAEA 900
>sp|Q7ZYG4|OSTF1_XENLA Osteoclast-stimulating factor 1 OS=Xenopus
laevis OX=8355 GN=ostf1 PE=2 SV=1
Length=214
Score = 59.7 bits (143), Expect = 9e-09, Method: Composition-based stats.
Identities = 19/80 (24%), Positives = 35/80 (44%), Gaps = 13/80 (16%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
+A + ++P L F++GDIL++ D NWW+ +G GL+P
Sbjct 18 RALYTFEPRTPDE-------LYFEEGDILYIADMSDTNWWKGTCKGKT------GLIPSN 64
Query 411 SFQQQREAMKQTIEEDKEPE 430
+Q E++ + E +
Sbjct 65 YVAEQAESIDNPLHEAAKRG 84
>sp|B2RUJ5|APBA1_MOUSE Amyloid-beta A4 precursor protein-binding
family A member 1 OS=Mus musculus OX=10090 GN=Apba1 PE=1
SV=2
Length=842
Score = 62.4 bits (150), Expect = 9e-09, Method: Composition-based stats.
Identities = 46/220 (21%), Positives = 88/220 (40%), Gaps = 13/220 (6%)
Query 126 DLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISN 185
DLF S + I+ D+Q L + D N + + + +
Sbjct 523 DLFISTQRIKVLNADTQEPMMDHPLRTISYIADIGNIVVLMARRRMPRSNSQENVEASHP 582
Query 186 AQDLAQEVQTVLKPVHHKEGQELTALLNTPH---IQALLLAH----DKVAEQEM-QLEPI 237
+QD ++ + + ++ Q + + Q L A+ + ++++E L
Sbjct 583 SQDGKRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDLLNT 642
Query 238 TDERVYESIGQYGGETVKIVRIEKARDIPLGATV-----RNEMDSVIISRIVKGGAAEKS 292
D + I E K V IEK + LG + + + +VII+ ++ GG AEKS
Sbjct 643 QDMYNDDLIHFSKSENCKDVFIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKS 702
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
G L+ GD+++ ING + G ++ ++ + L
Sbjct 703 GKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKL 742
Score = 57.4 bits (137), Expect = 4e-07, Method: Composition-based stats.
Identities = 19/84 (23%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
L + + + II +++GG AE+ G + G ++EING + ++ +LS+ G
Sbjct 760 LRYQLGFSVQNGIICSLMRGGIAER-GGVRVGHRIIEINGQSVVATPHEKIVHILSNAVG 818
Query 327 TLTFVLIPSQQIKPPPAKETVIHV 350
+ +P+ + A+E +++
Sbjct 819 EIHMKTMPAAMYRLLTAQEQPVYI 842
>sp|Q02410|APBA1_HUMAN Amyloid-beta A4 precursor protein-binding
family A member 1 OS=Homo sapiens OX=9606 GN=APBA1 PE=1 SV=3
Length=837
Score = 62.4 bits (150), Expect = 1e-08, Method: Composition-based stats.
Identities = 30/112 (27%), Positives = 53/112 (47%), Gaps = 6/112 (5%)
Query 227 VAEQEM-QLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV-----RNEMDSVII 280
++++E L D + I E K V IEK + LG + + + +VII
Sbjct 626 LSQKEYSDLLNTQDMYNDDLIHFSKSENCKDVFIEKQKGEILGVVIVESGWGSILPTVII 685
Query 281 SRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ ++ GG AEKSG L+ GD+++ ING + G ++ ++ + L
Sbjct 686 ANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKL 737
Score = 57.4 bits (137), Expect = 3e-07, Method: Composition-based stats.
Identities = 19/84 (23%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
L + + + II +++GG AE+ G + G ++EING + ++ +LS+ G
Sbjct 755 LRYQLGFSVQNGIICSLMRGGIAER-GGVRVGHRIIEINGQSVVATPHEKIVHILSNAVG 813
Query 327 TLTFVLIPSQQIKPPPAKETVIHV 350
+ +P+ + A+E +++
Sbjct 814 EIHMKTMPAAMYRLLTAQEQPVYI 837
>sp|Q8N448|LNX2_HUMAN Ligand of Numb protein X 2 OS=Homo sapiens
OX=9606 GN=LNX2 PE=1 SV=1
Length=690
Score = 62.4 bits (150), Expect = 1e-08, Method: Composition-based stats.
Identities = 18/101 (18%), Positives = 38/101 (38%), Gaps = 2/101 (2%)
Query 242 VYESIGQYGGETVKIVRIEKARDIPLGATV--RNEMDSVIISRIVKGGAAEKSGLLHEGD 299
+ E ++ ++ LG + R + V I +++GG A + G L D
Sbjct 326 NHSDSNSPREEIFQVALHKRDSGEQLGIKLVRRTDEPGVFILDLLEGGLAAQDGRLSSND 385
Query 300 EVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
VL ING +++ ++ + + + +P
Sbjct 386 RVLAINGHDLKYGTPELAAQIIQASGERVNLTIARPGKPQP 426
Score = 57.4 bits (137), Expect = 3e-07, Method: Composition-based stats.
Identities = 32/173 (18%), Positives = 54/173 (31%), Gaps = 22/173 (13%)
Query 235 EPITDERVYESIGQYGGETV---KIVRIEKARDIPLGATVRNEMD------SVIISRIVK 285
P S K + ++K LG TV + ++ +
Sbjct 444 TPPPYYSRPSSHKDLTQCVTCQEKHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVPP 503
Query 286 GGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS--DMHGTLTFVLIPSQQIKPPP- 342
G + G + GD +L INGI++ +E +L + + Q ++
Sbjct 504 HGCLARDGRIKRGDVLLNINGIDLTNLSHSEAVAMLKASAASPAVALKALEVQIVEEATQ 563
Query 343 AKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILH-----VISQEDPNWW 390
E + +YD S P LGL LH V+ + W
Sbjct 564 NAEEQPSTFSENEYDASWSPSW-VMWLGLP----STLHSCHDIVLRRSYLGSW 611
Score = 52.4 bits (124), Expect = 1e-05, Method: Composition-based stats.
Identities = 16/76 (21%), Positives = 33/76 (43%), Gaps = 2/76 (3%)
Query 264 DIPLGATVRNEMD--SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ + NE +++I + + G + G L GD++L++N I N +L
Sbjct 244 QLGISIVGGNETPLINIVIQEVYRDGVIARDGRLLAGDQILQVNNYNISNVSHNYARAVL 303
Query 322 SDMHGTLTFVLIPSQQ 337
S TL ++ ++
Sbjct 304 SQPCNTLHLTVLRERR 319
Score = 50.8 bits (120), Expect = 4e-05, Method: Composition-based stats.
Identities = 15/61 (25%), Positives = 26/61 (43%), Gaps = 0/61 (0%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ I IV G A G L GD ++ +NG+ G + + +L + +T +
Sbjct 623 HTNQPFFIKTIVLGTPAYYDGRLKCGDMIVAVNGLSTVGMSHSALVPMLKEQRNKVTLTV 682
Query 333 I 333
I
Sbjct 683 I 683
>sp|Q9QZR8|PDZD2_RAT PDZ domain-containing protein 2 OS=Rattus
norvegicus OX=10116 GN=Pdzd2 PE=1 SV=1
Length=2766
Score = 62.8 bits (151), Expect = 1e-08, Method: Composition-based stats.
Identities = 23/93 (25%), Positives = 43/93 (46%), Gaps = 6/93 (6%)
Query 254 VKIVRIEKARDIPLGATVRNEMD------SVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
+ I+ + K + LG ++ D + + I G+A + G L EGDE+L++NGI
Sbjct 533 ISIIGLYKEKGKGLGFSIAGGRDCIRGQMGIFVKTIFPNGSAAEDGRLKEGDEILDVNGI 592
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
I+G E + L + + ++ + P
Sbjct 593 PIKGLTFQEAIHTFKQIRSGLFVLTVRTKLLSP 625
Score = 62.0 bits (149), Expect = 2e-08, Method: Composition-based stats.
Identities = 21/106 (20%), Positives = 46/106 (43%), Gaps = 7/106 (7%)
Query 248 QYGGETVKIVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLE 303
+ G K+ ++++ + + + +++++++ +GGAA + G L GDE+L
Sbjct 327 EEVGRIWKMELLKESDGLGIQVSGGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDELLV 386
Query 304 INGIEIRGKDVNEVFDLLSDMHGTLTFVL---IPSQQIKPPPAKET 346
ING + G E +L G + V+ +P +
Sbjct 387 INGHLLVGLSHEEAVAILRSATGMVQLVVASKMPGSEESQDVGSSE 432
Score = 57.4 bits (137), Expect = 5e-07, Method: Composition-based stats.
Identities = 42/244 (17%), Positives = 83/244 (34%), Gaps = 50/244 (20%)
Query 134 IQHTLVDSQSQEDISLLLQLVQNKDFQNA--------------FKIHNAITVHMNKASPP 179
IQ S+++EDI + ++ K+ +H V +
Sbjct 2535 IQEAKAQSETKEDICFI--VLNKKEGSGLGFSVAGGADVEPKSVMVH---RVFSQGVASQ 2589
Query 180 FPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHD-KVAEQEMQLEPIT 238
+S L T L + H E ++ QA L H + ++ +
Sbjct 2590 EGTVSRGDFLLSVNGTSLAGLAHSEVTKVLH-------QAELHKHALMIIKKGNDQPGPS 2642
Query 239 DERVYESIGQYGGETVKIVRIEKA-----------------RDIPLGATVRNEM------ 275
++ S G + + +E LG ++
Sbjct 2643 FKQEPPSANGKGPFPRRTLPLEPGAGRNGAAHDALCVEVLKTSAGLGLSLDGGKSSVSGE 2702
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
++I R+ KGGAAE++G + GDE+L ING + G + ++++ + ++I
Sbjct 2703 GPLVIKRVYKGGAAERAGTIEAGDEILAINGKPLVGLVHFDAWNIMKSVPEGPVQLVIRK 2762
Query 336 QQIK 339
+
Sbjct 2763 HRDS 2766
Score = 55.1 bits (131), Expect = 2e-06, Method: Composition-based stats.
Identities = 25/136 (18%), Positives = 51/136 (38%), Gaps = 13/136 (10%)
Query 250 GGETVKIVR---IEKARDIPLGA-----TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEV 301
G +IV + K + LG + N + I + G A+ L GD++
Sbjct 670 PGPKDRIVMEVTLNKEPRVGLGIGACCLALENSPPGIYIHSLAPGSVAKMESNLSRGDQI 729
Query 302 LEINGIEIRGKDVNEVFDLLSD-MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
LE+N + +R +++V +LS G + V+ K + + ++ +
Sbjct 730 LEVNSVNVRHAALSKVHAILSKCPPGPVRLVIGRHPNPKVSEQEMDEVIARSTYQESREA 789
Query 361 DP----YVPCRELGLS 372
+ P + L+
Sbjct 790 NSSPGLGTPLKSPSLA 805
>sp|Q63R14|PHNN_BURPS Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Burkholderia pseudomallei (strain K96243) OX=272560 GN=phnN
PE=3 SV=1
Length=184
Score = 58.9 bits (141), Expect = 1e-08, Method: Composition-based stats.
Identities = 30/158 (19%), Positives = 53/158 (34%), Gaps = 21/158 (13%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
R + ++GP G++ L ++ R A A + TR + D + ++R F A
Sbjct 5 RLVYVMGPSGAGKDSLLAYARKHVREPRIAFAHRYITR-KSDGHENHVE---LTRDEFAA 60
Query 539 DIAAGKF-IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS------LKTLRNSDLK 591
G F +E YG ++ + + +G + + R +
Sbjct 61 RAQLGFFALEWSS-HGFRYGVGVE-IDAWLAAGSVVV----VSGSRAHLPAALERYPQMC 114
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTR 629
I AP L LA G+ E + R
Sbjct 115 VVHIDAAP---HVLAERLATRGRETADEIRARLARSVR 149
>sp|A1V0B1|PHNN_BURMS Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Burkholderia mallei (strain SAVP1) OX=320388 GN=phnN PE=3
SV=1
Length=184
Score = 58.9 bits (141), Expect = 1e-08, Method: Composition-based stats.
Identities = 30/158 (19%), Positives = 53/158 (34%), Gaps = 21/158 (13%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKD-RFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
R + ++GP G++ L ++ R A A + TR + D + ++R F A
Sbjct 5 RLVYVMGPSGAGKDSLLAYARKHVREPRIAFAHRYITR-KSDGHENHVE---LTRDEFAA 60
Query 539 DIAAGKF-IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS------LKTLRNSDLK 591
G F +E YG ++ + + +G + + R +
Sbjct 61 RAQLGFFALEWSS-HGFRYGVGVE-IDAWLAAGSVVV----VSGSRAHLPAALERYPQMC 114
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTR 629
I AP L LA G+ E + R
Sbjct 115 VVHIDAAP---HVLAERLATRGRETADEIRARLARSVR 149
>sp|Q96L92|SNX27_HUMAN Sorting nexin-27 OS=Homo sapiens OX=9606
GN=SNX27 PE=1 SV=2
Length=541
Score = 62.0 bits (149), Expect = 1e-08, Method: Composition-based stats.
Identities = 28/126 (22%), Positives = 56/126 (44%), Gaps = 18/126 (14%)
Query 255 KIVRIEKARDIPLGATVRNEM----------DSVI-----ISRIVKGGAAEKSGLLHEGD 299
++VRI K+ + G VR ++ + +S ++ GGAA+++G + +GD
Sbjct 42 RVVRIVKS-ESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAG-VRKGD 99
Query 300 EVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPS 359
+LE+N + + G +V DL+ L ++ + + + F YD +
Sbjct 100 RILEVNHVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSF-YDYT 158
Query 360 DDPYVP 365
+ VP
Sbjct 159 EKQAVP 164
>sp|P29355|SEM5_CAEEL Sex muscle abnormal protein 5 OS=Caenorhabditis
elegans OX=6239 GN=sem-5 PE=1 SV=1
Length=228
Score = 59.7 bits (143), Expect = 1e-08, Method: Composition-based stats.
Identities = 17/64 (27%), Positives = 32/64 (50%), Gaps = 13/64 (20%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
V+A FD++P + L+F++GD++ +I+++DPNWW+ G+ P
Sbjct 158 FVQALFDFNPQESGE-------LAFKRGDVITLINKDDPNWWEGQL------NNRRGIFP 204
Query 409 GKSF 412
Sbjct 205 SNYV 208
Score = 41.2 bits (95), Expect = 0.017, Method: Composition-based stats.
Identities = 14/44 (32%), Positives = 28/44 (64%), Gaps = 7/44 (16%)
Query 371 LSFQKGDILHVISQE-DPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
LSF++G+ L V++++ DP+W++A +G+E G +P +
Sbjct 17 LSFKRGNTLKVLNKDEDPHWYKAELDGNE------GFIPSNYIR 54
>sp|P42685|FRK_HUMAN Tyrosine-protein kinase FRK OS=Homo sapiens
OX=9606 GN=FRK PE=1 SV=1
Length=505
Score = 61.6 bits (148), Expect = 1e-08, Method: Composition-based stats.
Identities = 32/141 (23%), Positives = 46/141 (33%), Gaps = 22/141 (16%)
Query 321 LSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILH 380
LS T + P P + V A FDY LSF+ GD L
Sbjct 19 LSTEADKSTVIENPGALCSPQSQRHGHYFV-ALFDYQARTAED-------LSFRAGDKLQ 70
Query 381 VISQEDPNWWQAY---REGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWC 437
V+ WW A + D +Q L G +P + R + +
Sbjct 71 VLDTLHEGWWFARHLEKRRDGSSQQLQGYIPSNYVAEDR-----------SLQAEPWFFG 119
Query 438 AKKNKKKRKKVLYNANKNDDY 458
A K++LY+ NK +
Sbjct 120 AIGRSDAEKQLLYSENKTGSF 140
>sp|Q9WU22|PTN4_MOUSE Tyrosine-protein phosphatase non-receptor
type 4 OS=Mus musculus OX=10090 GN=Ptpn4 PE=1 SV=2
Length=926
Score = 62.0 bits (149), Expect = 1e-08, Method: Composition-based stats.
Identities = 37/185 (20%), Positives = 68/185 (37%), Gaps = 19/185 (10%)
Query 190 AQEVQTVLKPVHHKEGQELTALLNTPHI---QALLLAHDKVAEQEMQLEPITDERVYESI 246
+QE +P Q N H Q L+ H + + ++
Sbjct 453 SQETPEDGQPPALPPKQSKKNSWNQIHFSNSQQDLVTH---TNESFDVPSSPEKSTPN-- 507
Query 247 GQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEKS-GLLHEGDEVL 302
G + + +++++ + G V+ D VI+SR+ G A+ L+EGD+V+
Sbjct 508 GGIPHDNLVLIKMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEGDQVV 567
Query 303 EINGIEIRGKDVNEVFDLLSDM----HGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDP 358
ING +I ++V + G L ++ P+ E + + F Y P
Sbjct 568 LINGRDIAEHTHDQVVLFIKASCEKHSGELVLLVRPNAVYDVV---EEKLESEPDFQYIP 624
Query 359 SDDPY 363
P
Sbjct 625 EKAPL 629
>sp|Q5ZJJ9|OSTF1_CHICK Osteoclast-stimulating factor 1 OS=Gallus
gallus OX=9031 GN=OSTF1 PE=2 SV=1
Length=202
Score = 58.9 bits (141), Expect = 1e-08, Method: Composition-based stats.
Identities = 18/80 (23%), Positives = 35/80 (44%), Gaps = 13/80 (16%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
+A + ++P L F++GDI+++ D NWW+ +G GL+P
Sbjct 18 RALYTFEPRTPDE-------LYFEEGDIIYISDMSDTNWWKGTCKG------RTGLIPSN 64
Query 411 SFQQQREAMKQTIEEDKEPE 430
+Q E++ + E +
Sbjct 65 YVAEQAESIDNPLHEAAKRG 84
>sp|P19517|CACB1_RABIT Voltage-dependent L-type calcium channel
subunit beta-1 OS=Oryctolagus cuniculus OX=9986 GN=CACNB1
PE=1 SV=1
Length=524
Score = 61.6 bits (148), Expect = 1e-08, Method: Composition-based stats.
Identities = 62/424 (15%), Positives = 124/424 (29%), Gaps = 84/424 (20%)
Query 310 RGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCREL 369
+ E + L + + KP V+ + Y+PS VP +
Sbjct 70 SDVSLEEDREALRKEAERQALAQLEKAKTKPVA-----FAVRTNVGYNPSPGDEVPVEGV 124
Query 370 GLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK-------SFQQQREA---- 418
++F+ D LH+ + + +WW G +P Q+Q+
Sbjct 125 AITFEPKDFLHIKEKYNNDWWIGRLV---KEGCEVGFIPSPVKLDSLRLLQEQKLRQSRL 181
Query 419 --------------------MKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDY 458
+ T + + ++ + L + +
Sbjct 182 SSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELEPLDLEEDEAELGEQSGSAKT 241
Query 459 DNEEILT------------YEEMSLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKE 503
+ T E + RPIIL+GP G + +++ L +
Sbjct 242 SVSSVTTPPPHGTRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFL 301
Query 504 KDRFASAVPHTTR------SRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYG 557
K F + T ++R + + R + + E +
Sbjct 302 KHLFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSL--------AEVQ----- 348
Query 558 TSIDSVRQVINSGKI---CLLSLR-TQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEG 613
+ ++ + L L + L P I++I S + L+ L+ G
Sbjct 349 ---SEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRG 405
Query 614 KNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN---KLDTEPQWVP 670
K + + L I + ++ Q FD + + L+ A + L + K P P
Sbjct 406 K-SQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTP 464
Query 671 STWL 674
L
Sbjct 465 PNPL 468
>sp|O35867|NEB1_RAT Neurabin-1 OS=Rattus norvegicus OX=10116 GN=Ppp1r9a
PE=1 SV=1
Length=1095
Score = 61.6 bits (148), Expect = 2e-08, Method: Composition-based stats.
Identities = 30/152 (20%), Positives = 61/152 (40%), Gaps = 20/152 (13%)
Query 230 QEMQLEPITDERVYESIGQYGGETVKIVRIEKARD--------IPLGATVRNEMDSVIIS 281
+ ++P+ YE + + V +EK D + +GA E + +
Sbjct 479 RNDDVDPVAASAEYELEKRVEKLELFPVELEKDEDGLGISIIGMGVGADAGLEKLGIFVK 538
Query 282 RIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS------ 335
+ +GGAA++ G + D+++E++GI + G N +L + G + FV+
Sbjct 539 TVTEGGAAQRDGRIQVNDQIVEVDGISLVGVTQNFAATVLRNTKGNVRFVIGREKPGQVS 598
Query 336 ------QQIKPPPAKETVIHVKAHFDYDPSDD 361
Q ++ + + + YD DD
Sbjct 599 EVAQLISQTLEQERRQRELLERHYAQYDADDD 630
>sp|Q8MJ49|OSTF1_PIG Osteoclast-stimulating factor 1 OS=Sus scrofa
OX=9823 GN=OSTF1 PE=2 SV=1
Length=214
Score = 58.9 bits (141), Expect = 2e-08, Method: Composition-based stats.
Identities = 18/80 (23%), Positives = 35/80 (44%), Gaps = 13/80 (16%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
+A + ++P L F++GDI+++ D NWW+ +G GL+P
Sbjct 18 RALYTFEPRTPDE-------LYFEEGDIIYITDMSDTNWWKGTSKG------RTGLIPSN 64
Query 411 SFQQQREAMKQTIEEDKEPE 430
+Q E++ + E +
Sbjct 65 YVAEQAESIDNPLHEAAKRG 84
>sp|Q92882|OSTF1_HUMAN Osteoclast-stimulating factor 1 OS=Homo
sapiens OX=9606 GN=OSTF1 PE=1 SV=2
Length=214
Score = 58.9 bits (141), Expect = 2e-08, Method: Composition-based stats.
Identities = 18/80 (23%), Positives = 35/80 (44%), Gaps = 13/80 (16%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
+A + ++P L F++GDI+++ D NWW+ +G GL+P
Sbjct 18 RALYTFEPRTPDE-------LYFEEGDIIYITDMSDTNWWKGTSKG------RTGLIPSN 64
Query 411 SFQQQREAMKQTIEEDKEPE 430
+Q E++ + E +
Sbjct 65 YVAEQAESIDNPLHEAAKRG 84
>sp|Q29498|NOS1_SHEEP Nitric oxide synthase 1 OS=Ovis aries OX=9940
GN=NOS1 PE=2 SV=3
Length=1463
Score = 61.6 bits (148), Expect = 2e-08, Method: Composition-based stats.
Identities = 31/103 (30%), Positives = 47/103 (46%), Gaps = 2/103 (2%)
Query 248 QYGGETVKIVRIEKARDIPLGATVRNEM--DSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
Q V VR+ K + LG V+ + VIIS +++GGAAE+SGL+ GD +L +N
Sbjct 9 QQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVN 68
Query 306 GIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVI 348
G + + ++L + VLI ET
Sbjct 69 GQPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTF 111
>sp|A4D2P6|GRD2I_HUMAN Delphilin OS=Homo sapiens OX=9606 GN=GRID2IP
PE=3 SV=2
Length=1211
Score = 61.6 bits (148), Expect = 2e-08, Method: Composition-based stats.
Identities = 22/83 (27%), Positives = 39/83 (47%), Gaps = 3/83 (4%)
Query 250 GGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
G + VR+ K + G T+R V I ++ G A+ + L GD +L +NG+++
Sbjct 273 PGGARRTVRVYKG-NKSFGFTLRGH-GPVWIESVLPGSPAD-NAALKSGDRILFLNGLDM 329
Query 310 RGKDVNEVFDLLSDMHGTLTFVL 332
R ++V +L T V+
Sbjct 330 RNCSHDKVVSMLQGSGAMPTLVV 352
Score = 43.1 bits (100), Expect = 0.011, Method: Composition-based stats.
Identities = 13/56 (23%), Positives = 24/56 (43%), Gaps = 2/56 (4%)
Query 265 IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDL 320
G + + + KG +A +G L GD++LE+ G+ + G + L
Sbjct 15 EDFGFRLGGS-GPCFVLEVAKGSSAH-AGGLRPGDQILEVEGLAVGGLSRERLVRL 68
>sp|Q9JKS6|PCLO_RAT Protein piccolo OS=Rattus norvegicus OX=10116
GN=Pclo PE=1 SV=1
Length=5085
Score = 61.6 bits (148), Expect = 2e-08, Method: Composition-based stats.
Identities = 22/77 (29%), Positives = 38/77 (49%), Gaps = 4/77 (5%)
Query 257 VRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
+RI ++IP + I++I+ G +AE +G L EG +VLE NG+ + K E
Sbjct 4461 IRIVGGKEIP----GHSGEIGAYIAKILPGESAEHTGPLMEGMQVLEWNGVPLTSKTYEE 4516
Query 317 VFDLLSDMHGTLTFVLI 333
V +++ G +
Sbjct 4517 VQSIINQQSGEAEICVR 4533
>sp|Q6ZM86|GRD2I_DANRE Delphilin OS=Danio rerio OX=7955 GN=grid2ip
PE=3 SV=1
Length=1009
Score = 61.2 bits (147), Expect = 3e-08, Method: Composition-based stats.
Identities = 33/149 (22%), Positives = 57/149 (38%), Gaps = 19/149 (13%)
Query 225 DKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIV 284
D+ A+ + L + + T+++ R +K+ G T+R V I ++
Sbjct 67 DEPAQNDRTLRKSNTMIPTQYVSGVNQRTIRVYRGKKS----FGFTLRGH-APVWIDSVM 121
Query 285 KGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAK 344
G AE G L GD +L +NG+++R +V +L + V+ P
Sbjct 122 PGSPAEACG-LKTGDRILFLNGLDMRNCSHEKVVSMLQGSGAMPSLVVEEGPVDYPQS-- 178
Query 345 ETVIHVKAHFDYDPSDDPYVP-CRELGLS 372
D +P + P P R LS
Sbjct 179 ----------DSEPEETPSAPRSRSPALS 197
>sp|Q68DX3|FRPD2_HUMAN FERM and PDZ domain-containing protein
2 OS=Homo sapiens OX=9606 GN=FRMPD2 PE=1 SV=3
Length=1309
Score = 61.2 bits (147), Expect = 3e-08, Method: Composition-based stats.
Identities = 22/118 (19%), Positives = 43/118 (36%), Gaps = 9/118 (8%)
Query 235 EPITDERVYESIGQYGGETVKIVRIEKARDIPL--GATVRNEMDSVIISRIVKGGAAEKS 292
P E I V++V+ + + G + + IV GG A K
Sbjct 937 PPSPPEISAGEIYF-----VELVKEDGTLGFSVTGGINTSVPYGGIYVKSIVPGGPAAKE 991
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS--QQIKPPPAKETVI 348
G + +GD +L+++G+ + G + L+ VL + + P+ +
Sbjct 992 GQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLVLERRVPRSTQQCPSANDSM 1049
Score = 59.3 bits (142), Expect = 1e-07, Method: Composition-based stats.
Identities = 19/98 (19%), Positives = 39/98 (40%), Gaps = 6/98 (6%)
Query 244 ESIGQYGGETVKIVRIEKARDIPLGATV------RNEMDSVIISRIVKGGAAEKSGLLHE 297
+S G + V +++ G + + IS I+ GG AEK+ +
Sbjct 763 KSFIAEPGREIVRVTLKRDPHRGFGFVINEGEYSGQADPGIFISSIIPGGPAEKAKTIKP 822
Query 298 GDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
G ++L +N I + G N ++ + + ++ S
Sbjct 823 GGQILALNHISLEGFTFNMAVRMIQNSPDNIELIISQS 860
Score = 53.5 bits (127), Expect = 6e-06, Method: Composition-based stats.
Identities = 26/114 (23%), Positives = 38/114 (33%), Gaps = 19/114 (17%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP----- 334
I R+ G AE++G + GD +L +NG G EV LL +T +L
Sbjct 1111 IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGA 1170
Query 335 ----SQQIKPPPAKETVIHVKA----------HFDYDPSDDPYVPCRELGLSFQ 374
Q+ + P +A D D P GL +
Sbjct 1171 LPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLR 1224
>sp|Q920G2|NHRF2_RAT Na(+)/H(+) exchange regulatory cofactor NHE-RF2
OS=Rattus norvegicus OX=10116 GN=Nherf2 PE=1 SV=1
Length=337
Score = 59.7 bits (143), Expect = 3e-08, Method: Composition-based stats.
Identities = 18/101 (18%), Positives = 41/101 (41%), Gaps = 3/101 (3%)
Query 245 SIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEI 304
+ ++VR E+ L I R+ G AE + L GD ++E+
Sbjct 3 APESLRPRLCRLVRGEQGYGFHLHGEKGRRGQ--FIRRVEPGSPAE-AAALRAGDRLVEV 59
Query 305 NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKE 345
NG+ + G+ ++V + + G +++ + + ++
Sbjct 60 NGVNVEGETHHQVVHRIKAVEGQTQLLVVDKETDEELCRRQ 100
Score = 45.8 bits (107), Expect = 8e-04, Method: Composition-based stats.
Identities = 21/166 (13%), Positives = 48/166 (29%), Gaps = 9/166 (5%)
Query 182 LISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHI--QALLLAHDKVAEQEMQLEPITD 239
++ + + + Q ++ E L T + + L AH+ +
Sbjct 72 VVHRIKAVEGQTQLLVVDKETDEELCRRQLTCTEEMAHRGLPPAHNPWEPK-PDWACSGS 130
Query 240 ERVYESIGQYGGETV----KIVRIEKA-RDIPLGATVRNEMDSVIISRIVKGGAAEKSGL 294
G ++ + + + I + G A SG
Sbjct 131 LGSDTGHKDVNGPPRELRPRLCHLRRGPQGYGFNLHSDKSRPGQYIRSVDPGSPASLSG- 189
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
L D ++E+NG + G EV + +++ + +
Sbjct 190 LRAQDRLIEVNGQNVEGLRHAEVVARIKAQEDEARLLVVDPETDEH 235
>sp|O14907|TX1B3_HUMAN Tax1-binding protein 3 OS=Homo sapiens
OX=9606 GN=TAX1BP3 PE=1 SV=2
Length=124
Score = 55.8 bits (133), Expect = 3e-08, Method: Composition-based stats.
Identities = 19/119 (16%), Positives = 52/119 (44%), Gaps = 16/119 (13%)
Query 242 VYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---------------SVIISRIVKG 286
+ + V+I ++ + ++ LG ++ +D + ++R+ +G
Sbjct 4 IPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEG 63
Query 287 GAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKE 345
G AE +G L GD+++++NG ++ ++ L+ + +L+ Q ++ +
Sbjct 64 GPAEIAG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQQS 121
>sp|Q6P686|OSTF1_RAT Osteoclast-stimulating factor 1 OS=Rattus
norvegicus OX=10116 GN=Ostf1 PE=1 SV=1
Length=214
Score = 58.1 bits (139), Expect = 3e-08, Method: Composition-based stats.
Identities = 17/80 (21%), Positives = 35/80 (44%), Gaps = 13/80 (16%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
+A + ++P L F++GDI+++ D +WW+ +G GL+P
Sbjct 18 RALYTFEPRTPDE-------LYFEEGDIIYITDMSDTSWWKGTCKG------RTGLIPSN 64
Query 411 SFQQQREAMKQTIEEDKEPE 430
+Q E++ + E +
Sbjct 65 YVAEQAESIDNPLHEAAKRG 84
>sp|Q62422|OSTF1_MOUSE Osteoclast-stimulating factor 1 OS=Mus
musculus OX=10090 GN=Ostf1 PE=1 SV=2
Length=215
Score = 58.1 bits (139), Expect = 3e-08, Method: Composition-based stats.
Identities = 17/80 (21%), Positives = 35/80 (44%), Gaps = 13/80 (16%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
+A + ++P L F++GDI+++ D +WW+ +G GL+P
Sbjct 18 RALYTFEPRTPDE-------LYFEEGDIIYITDMSDTSWWKGTCKG------RTGLIPSN 64
Query 411 SFQQQREAMKQTIEEDKEPE 430
+Q E++ + E +
Sbjct 65 YVAEQAESIDNPLHEAAKRG 84
>sp|Q9DBG9|TX1B3_MOUSE Tax1-binding protein 3 OS=Mus musculus
OX=10090 GN=Tax1bp3 PE=1 SV=1
Length=124
Score = 55.8 bits (133), Expect = 3e-08, Method: Composition-based stats.
Identities = 23/119 (19%), Positives = 52/119 (44%), Gaps = 19/119 (16%)
Query 245 SIGQYGGETVKIVRIEK---ARDIPLGATVRNEMD---------------SVIISRIVKG 286
+ GQ V+ V I K ++ LG ++ +D + ++R+ +G
Sbjct 4 TPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEG 63
Query 287 GAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKE 345
G AE +G L GD+++++NG ++ ++ L+ + +L+ Q ++ +
Sbjct 64 GPAEIAG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQQS 121
>sp|Q9ULJ8|NEB1_HUMAN Neurabin-1 OS=Homo sapiens OX=9606 GN=PPP1R9A
PE=1 SV=2
Length=1098
Score = 60.8 bits (146), Expect = 4e-08, Method: Composition-based stats.
Identities = 35/193 (18%), Positives = 73/193 (38%), Gaps = 25/193 (13%)
Query 194 QTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQ-----LEPITDERVYESIGQ 248
+ V E +E+ A A + + + ++ ++P+ YE +
Sbjct 437 MEYSEIVGLPEEEEIPANRKIKFSSAPIKVFNTYSNEDYDRRNDEVDPVAASAEYELEKR 496
Query 249 YGGETVKIVRIEKARD--------IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDE 300
+ V +EK D + +GA E + + + +GGAA++ G + D+
Sbjct 497 VEKLELFPVELEKDEDGLGISIIGMGVGADAGLEKLGIFVKTVTEGGAAQRDGRIQVNDQ 556
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS------------QQIKPPPAKETVI 348
++E++GI + G N +L + G + FV+ Q ++ +
Sbjct 557 IVEVDGISLVGVTQNFAATVLRNTKGNVRFVIGREKPGQVSEVAQLISQTLEQERRQREL 616
Query 349 HVKAHFDYDPSDD 361
+ + YD DD
Sbjct 617 LEQHYAQYDADDD 629
>sp|P29475|NOS1_HUMAN Nitric oxide synthase 1 OS=Homo sapiens
OX=9606 GN=NOS1 PE=1 SV=2
Length=1434
Score = 60.5 bits (145), Expect = 5e-08, Method: Composition-based stats.
Identities = 31/103 (30%), Positives = 47/103 (46%), Gaps = 2/103 (2%)
Query 248 QYGGETVKIVRIEKARDIPLGATVRNEM--DSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
Q V VR+ K + LG V+ + VIIS +++GGAAE+SGL+ GD +L +N
Sbjct 9 QQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVN 68
Query 306 GIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVI 348
G + + ++L + VLI ET
Sbjct 69 GRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTF 111
>sp|Q9JHL1|NHRF2_MOUSE Na(+)/H(+) exchange regulatory cofactor
NHE-RF2 OS=Mus musculus OX=10090 GN=Nherf2 PE=1 SV=2
Length=337
Score = 59.3 bits (142), Expect = 5e-08, Method: Composition-based stats.
Identities = 18/101 (18%), Positives = 41/101 (41%), Gaps = 3/101 (3%)
Query 245 SIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEI 304
+ ++VR E+ L I R+ G AE + L GD ++E+
Sbjct 3 APESLRPRLCRLVRGEQGYGFHLHGEKGRRGQ--FIRRVEPGSPAE-AAALRAGDRLVEV 59
Query 305 NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKE 345
NG+ + G+ ++V + + G +++ + + ++
Sbjct 60 NGVNVEGETHHQVVQRIKAVEGQTQLLVVDKETDEELCRRQ 100
Score = 44.7 bits (104), Expect = 0.002, Method: Composition-based stats.
Identities = 13/87 (15%), Positives = 29/87 (33%), Gaps = 2/87 (2%)
Query 255 KIVRIEKA-RDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
++ + + + I + G A SG L D ++E+NG + G
Sbjct 150 RLCHLRRGPQGYGFNLHSDKSRPGQYIRSVDPGSPASHSG-LRAQDRLIEVNGQNVEGLR 208
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKP 340
EV + +++ + +
Sbjct 209 HAEVVARIKAQEDEARLLVVDPETDEH 235
>sp|Q9P227|RHG23_HUMAN Rho GTPase-activating protein 23 OS=Homo
sapiens OX=9606 GN=ARHGAP23 PE=1 SV=2
Length=1491
Score = 60.5 bits (145), Expect = 5e-08, Method: Composition-based stats.
Identities = 19/80 (24%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
MD++ + + + G A ++G L GD ++++NG + GK ++V L+ + TL +
Sbjct 93 EPMDTIFVKNVKEDGPAHRAG-LRTGDRLVKVNGESVIGKTYSQVIALIQNSDDTLELSI 151
Query 333 IPSQQIKPPPAKETVIHVKA 352
+P + A ++K
Sbjct 152 MPKDEDILQLAYSQDAYLKG 171
>sp|Q8CC27|CACB2_MOUSE Voltage-dependent L-type calcium channel
subunit beta-2 OS=Mus musculus OX=10090 GN=Cacnb2 PE=1 SV=1
Length=655
Score = 60.1 bits (144), Expect = 5e-08, Method: Composition-based stats.
Identities = 56/369 (15%), Positives = 113/369 (31%), Gaps = 56/369 (15%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
Q++ K V+ + Y + + VP + +SF+ D LHV + + +WW
Sbjct 100 QAQLEKAKTKPVAFAVRTNVRYSAAQEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRL 159
Query 395 EGDEDNQPLAGLVPGK------SFQ-QQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKK 447
G +P Q +QR + S L + +K
Sbjct 160 V---KEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTP 216
Query 448 VLYN----------------ANKNDDYDNEEILTYEEMSLYHQPANRK------------ 479
AN + +T P +K
Sbjct 217 PSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPS 276
Query 480 -RPIILIGPQNCG---QNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
RP++L+GP G + +++ L + K RF + T + + S+ A
Sbjct 277 MRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHA 336
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKI---CLLSLR-TQSLKTLRNSDLK 591
+ E + + ++ + +L L + L
Sbjct 337 IIERSNTRSSL--AEVQ--------SEIERIFELARTLQLVVLDADTINHPAQLSKTSLA 386
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
P I+++ S + L+ L+ GK+ +++ + + FD + + L+ A
Sbjct 387 PIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPQESFDVILDENQLEDA 446
Query 652 YQELLRLIN 660
+ L +
Sbjct 447 CEHLADYLE 455
>sp|Q69ZH9|RHG23_MOUSE Rho GTPase-activating protein 23 OS=Mus
musculus OX=10090 GN=Arhgap23 PE=1 SV=2
Length=1483
Score = 60.5 bits (145), Expect = 5e-08, Method: Composition-based stats.
Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
MD++ + + GG A ++G L GD ++++NG I GK ++V L+ + TL +
Sbjct 93 EPMDTIFVKNVKDGGPAHRAG-LRTGDRLVKVNGESIIGKTYSQVIGLIQNSDDTLELSI 151
Query 333 IPSQQIKPPPAKETVIHVKA 352
+P + A ++K
Sbjct 152 MPKDEDILQLAYSQDAYLKG 171
>sp|Q8VGC3|CACB2_RAT Voltage-dependent L-type calcium channel
subunit beta-2 OS=Rattus norvegicus OX=10116 GN=Cacnb2 PE=1
SV=2
Length=655
Score = 59.7 bits (143), Expect = 7e-08, Method: Composition-based stats.
Identities = 56/369 (15%), Positives = 113/369 (31%), Gaps = 56/369 (15%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
Q++ K V+ + Y + + VP + +SF+ D LHV + + +WW
Sbjct 100 QAQLEKAKTKPVAFAVRTNVRYSAAQEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRL 159
Query 395 EGDEDNQPLAGLVPGK------SFQ-QQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKK 447
G +P Q +QR + S L + +K
Sbjct 160 V---KEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTP 216
Query 448 VLYN----------------ANKNDDYDNEEILTYEEMSLYHQPANRK------------ 479
AN + +T P +K
Sbjct 217 PSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPS 276
Query 480 -RPIILIGPQNCG---QNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
RP++L+GP G + +++ L + K RF + T + + S+ A
Sbjct 277 MRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHA 336
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKI---CLLSLR-TQSLKTLRNSDLK 591
+ E + + ++ + +L L + L
Sbjct 337 IIERSNTRSSL--AEVQ--------SEIERIFELARTLQLVVLDADTINHPAQLSKTSLA 386
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
P I+++ S + L+ L+ GK+ +++ + + FD + + L+ A
Sbjct 387 PIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPQESFDVILDENQLEDA 446
Query 652 YQELLRLIN 660
+ L +
Sbjct 447 CEHLADYLE 455
>sp|O62678|IL16_AOTTR Pro-interleukin-16 OS=Aotus trivirgatus
OX=9505 GN=IL16 PE=2 SV=1
Length=632
Score = 59.7 bits (143), Expect = 7e-08, Method: Composition-based stats.
Identities = 25/142 (18%), Positives = 56/142 (39%), Gaps = 19/142 (13%)
Query 205 GQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARD 264
GQ + +LL++ ++ L+ + ++ Q V I+ E+
Sbjct 378 GQSVISLLSSEELKKLIEE--------------VKDLDEATLKQLDSIHVTILHKEEGAG 423
Query 265 IPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
+ ++++ + + R+ G A + G + +G+EVL ING ++G N+ +L
Sbjct 424 LGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHNDALAILR 483
Query 323 DM---HGTLTFVLIPSQQIKPP 341
+ P+ + P
Sbjct 484 QAREPRQAVIVTRKPTPETAPD 505
Score = 51.2 bits (121), Expect = 3e-05, Method: Composition-based stats.
Identities = 56/252 (22%), Positives = 91/252 (36%), Gaps = 20/252 (8%)
Query 112 LESPHYAVKILEIEDLFS-SLKHIQHTLVDSQSQED-ISLLLQLVQNKDFQNAFKIHNAI 169
L S I E++DL +LK + V +E+ L L D +N K+
Sbjct 385 LSSEELKKLIEEVKDLDEATLKQLDSIHVTILHKEEGAGLGFSLAGGADLEN--KVITVH 442
Query 170 TVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAE 229
V N + I ++ LK H + + P QA+++ E
Sbjct 443 RVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHNDALAILRQAREPR-QAVIVTRKPTPE 501
Query 230 QEMQL------EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD------S 277
L S+ TV V +EK LG ++
Sbjct 502 TAPDLNSSTDSAASVSAASDVSVDSTAEATVCTVTLEKMSG-GLGFSLEGGKGSLHGDKP 560
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD-MHGTLTFVLIPSQ 336
+ I+RI KG A+E+S + GDE+L + G ++G E ++++ G +T V+
Sbjct 561 LTINRIFKGAASEQSETVQPGDEILHLAGTAMQGLTRFEAWNIIKALPDGPVTIVIKRKS 620
Query 337 -QIKPPPAKETV 347
Q K PA
Sbjct 621 MQSKGTPAAGDS 632
>sp|Q5ZM14|NHRF1_CHICK Na(+)/H(+) exchange regulatory cofactor
NHE-RF1 OS=Gallus gallus OX=9031 GN=NHERF1 PE=2 SV=1
Length=333
Score = 58.5 bits (140), Expect = 7e-08, Method: Composition-based stats.
Identities = 27/125 (22%), Positives = 45/125 (36%), Gaps = 10/125 (8%)
Query 245 SIGQYGGETVKIVRIEKA-RDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLE 303
S G ++ +EK I + G AE+SG L GD +LE
Sbjct 2 SSAPPGPAAPRLCCMEKGPDGYGFHLHGEKGKPGQYIRLVEAGSPAERSG-LRAGDRLLE 60
Query 304 INGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPY 363
++G + + +V + + G + +++ Q + PP K H D D
Sbjct 61 VDGTNVERESHQQVVERIRAAAGAVRLLVVQPQPEEQPP--------KTHSDPDGEAQRE 112
Query 364 VPCRE 368
P E
Sbjct 113 PPAAE 117
Score = 52.0 bits (123), Expect = 1e-05, Method: Composition-based stats.
Identities = 19/113 (17%), Positives = 37/113 (33%), Gaps = 3/113 (3%)
Query 223 AHDKVAEQEMQLEPITDERVYESIGQYGGETV-KIVRIEKA-RDIPLGATVRNEMDSVII 280
H + + P + E G E ++ RI+K +
Sbjct 101 THSDPDGEAQREPPAAETPAAERSGPEERELRPRLCRIKKGPNGYGFNLHSEKSRPGQYV 160
Query 281 SRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
+ AE +G L D ++E+NG + GK +V + +++
Sbjct 161 RAVDPDSPAEAAG-LRAQDRIVEVNGTSVEGKQHADVVAAIKAGGDETKLLVV 212
>sp|Q04929|CRK_CHICK Adapter molecule crk OS=Gallus gallus OX=9031
GN=CRK PE=1 SV=1
Length=305
Score = 58.1 bits (139), Expect = 8e-08, Method: Composition-based stats.
Identities = 26/109 (24%), Positives = 47/109 (43%), Gaps = 16/109 (15%)
Query 329 TFVLIPSQQIKPPP----AKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ 384
T ++ P + + +E V +V+A FD++ +DD +P F+KGDIL + +
Sbjct 113 TTLIEPVSRSRQNSGVILRQEEVEYVRALFDFNGNDDEDLP-------FKKGDILKIRDK 165
Query 385 EDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSG 433
+ WW A ED G++P ++ R + + S
Sbjct 166 PEEQWWNA-----EDMDGKRGMIPVPYVEKCRPSSASVSTLTGGNQDSS 209
>sp|Q8SQG9|NHRF2_RABIT Na(+)/H(+) exchange regulatory cofactor
NHE-RF2 OS=Oryctolagus cuniculus OX=9986 GN=NHERF2 PE=1 SV=1
Length=316
Score = 58.1 bits (139), Expect = 8e-08, Method: Composition-based stats.
Identities = 18/91 (20%), Positives = 40/91 (44%), Gaps = 3/91 (3%)
Query 255 KIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
++VR E+ L I R+ G AE + L GD ++E+NG+ + G+
Sbjct 13 RLVRGEQGYGFHLHGEKGRRGQ--FIRRVEPGSPAE-AAALRAGDRLVEVNGVNVEGETH 69
Query 315 NEVFDLLSDMHGTLTFVLIPSQQIKPPPAKE 345
++V + + G +++ + + ++
Sbjct 70 HQVVQRIKAVEGETRLLVVDKETDEELRRRQ 100
Score = 47.0 bits (110), Expect = 3e-04, Method: Composition-based stats.
Identities = 24/158 (15%), Positives = 53/158 (34%), Gaps = 7/158 (4%)
Query 182 LISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHI--QALLLAHDKVAEQE--MQLEPI 237
++ + + E + ++ E L T + + L AHD + + +
Sbjct 72 VVQRIKAVEGETRLLVVDKETDEELRRRQLTCTEDMAQRGLPPAHDPWEPKPDWARAGSL 131
Query 238 TDERVYESIGQYGGETV-KIVRIEKA-RDIPLGATVRNEMDSVIISRIVKGGAAEKSGLL 295
+ + + + E ++ + K + I + G A SGL
Sbjct 132 SSDAGQKDVNGPPRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAAHSGLC 191
Query 296 HEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
+ D ++E+NG + G EV + +L+
Sbjct 192 AQ-DRLIEVNGQNVEGLRHAEVVARIKAKEDEARLLLV 228
>sp|Q15599|NHRF2_HUMAN Na(+)/H(+) exchange regulatory cofactor
NHE-RF2 OS=Homo sapiens OX=9606 GN=NHERF2 PE=1 SV=2
Length=337
Score = 58.5 bits (140), Expect = 8e-08, Method: Composition-based stats.
Identities = 23/112 (21%), Positives = 48/112 (43%), Gaps = 4/112 (4%)
Query 255 KIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
++VR E+ L I R+ G AE + L GD ++E+NG+ + G+
Sbjct 13 RLVRGEQGYGFHLHGEKGRRGQ--FIRRVEPGSPAE-AAALRAGDRLVEVNGVNVEGETH 69
Query 315 NEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVK-AHFDYDPSDDPYVP 365
++V + + G +++ + + ++ + A P+ DP+ P
Sbjct 70 HQVVQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEMAQRGLPPAHDPWEP 121
Score = 48.1 bits (113), Expect = 1e-04, Method: Composition-based stats.
Identities = 14/87 (16%), Positives = 30/87 (34%), Gaps = 2/87 (2%)
Query 255 KIVRIEKA-RDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
++ + K + I + G A +SG L D ++E+NG + G
Sbjct 150 RLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAARSG-LRAQDRLIEVNGQNVEGLR 208
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKP 340
EV + +++ + +
Sbjct 209 HAEVVASIKAREDEARLLVVDPETDEH 235
>sp|O08992|SDCB1_MOUSE Syntenin-1 OS=Mus musculus OX=10090 GN=Sdcbp
PE=1 SV=1
Length=299
Score = 57.8 bits (138), Expect = 1e-07, Method: Composition-based stats.
Identities = 36/233 (15%), Positives = 75/233 (32%), Gaps = 34/233 (15%)
Query 165 IHNAITVHMNKASPPFPLISNAQDLAQEVQTVLK-----------PVHHKEGQELTALLN 213
I N AS F L+ + L + K ++ E E +++
Sbjct 16 IQAQTAYSANPASQAFVLVDASAALPPDGNLYPKLYPELSQYMGLSLNEAEICESMPMVS 75
Query 214 TPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRN 273
Q L+A + + + P+T + ++ V + K +D +G +++
Sbjct 76 GAPAQGQLVA--RPSSVNYMVAPVT-GNDAGIRRAEIKQGIREVILCKDQDGKIGLRLKS 132
Query 274 EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM-HGTLTFVL 332
+ + + + A G L GD+VL+ING G ++ +L +T +
Sbjct 133 IDNGIFVQLVQANSPASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTI 191
Query 333 IPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE 385
+ + +G F+ G I ++
Sbjct 192 RDRPFERTVTMHKDS------------------SGHVGFIFKSGKITSIVKDS 226
Score = 46.6 bits (109), Expect = 4e-04, Method: Composition-based stats.
Identities = 23/102 (23%), Positives = 46/102 (45%), Gaps = 5/102 (5%)
Query 255 KIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
+ V + K +G ++ I+ IVK +A ++GLL + EING + G
Sbjct 198 RTVTMHKDSSGHVGFIFKSGK----ITSIVKDSSAARNGLL-TDHHICEINGQNVIGLKD 252
Query 315 NEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDY 356
++ D+LS +T ++P+ + + +K+ D+
Sbjct 253 AQIADILSTAGTVVTITIMPTFIFEHIIKRMAPSIMKSLMDH 294
>sp|F1MCA7|LRRC7_BOVIN Leucine-rich repeat-containing protein
7 OS=Bos taurus OX=9913 GN=LRRC7 PE=3 SV=3
Length=1536
Score = 59.3 bits (142), Expect = 1e-07, Method: Composition-based stats.
Identities = 20/88 (23%), Positives = 33/88 (38%), Gaps = 11/88 (13%)
Query 257 VRIEKARDIPLGATVRNEMDS---------VIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
VRIEK + + + ++R+ G A S LL GD++L+ NG
Sbjct 1448 VRIEKNPGLGFSISGGISGQGNPFKPSDKGIFVTRVQPDGPA--SNLLQPGDKILQANGH 1505
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ + LL T+ V+
Sbjct 1506 SFVHMEHEKAVLLLKSFQNTVDLVIQRE 1533
>sp|O00560|SDCB1_HUMAN Syntenin-1 OS=Homo sapiens OX=9606 GN=SDCBP
PE=1 SV=1
Length=298
Score = 57.8 bits (138), Expect = 1e-07, Method: Composition-based stats.
Identities = 35/191 (18%), Positives = 76/191 (40%), Gaps = 7/191 (4%)
Query 160 QNAFKIHNAITVHMNKASPPFPLISNA-QDLAQEVQTVLK-PVHHKEGQELTALLNTPHI 217
Q AF + A +++AS P P N L E+ + ++ +E + A+++ +
Sbjct 19 QTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLSLNEEEIRANVAVVSGAPL 78
Query 218 QALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDS 277
Q L+A + + + P+T + ++ V + K +D +G +++ +
Sbjct 79 QGQLVA--RPSSINYMVAPVT-GNDVGIRRAEIKQGIREVILCKDQDGKIGLRLKSIDNG 135
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM-HGTLTFVLIPSQ 336
+ + + A G L GD+VL+ING G ++ +L +T +
Sbjct 136 IFVQLVQANSPASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRP 194
Query 337 QIKPPPAKETV 347
+ +
Sbjct 195 FERTITMHKDS 205
Score = 49.3 bits (116), Expect = 6e-05, Method: Composition-based stats.
Identities = 24/102 (24%), Positives = 49/102 (48%), Gaps = 5/102 (5%)
Query 255 KIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
+ + + K +G +N I+ IVK +A ++GLL E + + EING + G
Sbjct 197 RTITMHKDSTGHVGFIFKNGK----ITSIVKDSSAARNGLLTEHN-ICEINGQNVIGLKD 251
Query 315 NEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDY 356
+++ D+LS +T ++P+ + + +K+ D+
Sbjct 252 SQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDH 293
>sp|Q96NW7|LRRC7_HUMAN Leucine-rich repeat-containing protein
7 OS=Homo sapiens OX=9606 GN=LRRC7 PE=1 SV=1
Length=1537
Score = 59.3 bits (142), Expect = 1e-07, Method: Composition-based stats.
Identities = 20/88 (23%), Positives = 33/88 (38%), Gaps = 11/88 (13%)
Query 257 VRIEKARDIPLGATVRNEMDS---------VIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
VRIEK + + + ++R+ G A S LL GD++L+ NG
Sbjct 1449 VRIEKNPGLGFSISGGISGQGNPFKPSDKGIFVTRVQPDGPA--SNLLQPGDKILQANGH 1506
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ + LL T+ V+
Sbjct 1507 SFVHMEHEKAVLLLKSFQNTVDLVIQRE 1534
>sp|P70587|LRRC7_RAT Leucine-rich repeat-containing protein 7
OS=Rattus norvegicus OX=10116 GN=Lrrc7 PE=1 SV=2
Length=1490
Score = 59.3 bits (142), Expect = 1e-07, Method: Composition-based stats.
Identities = 20/88 (23%), Positives = 33/88 (38%), Gaps = 11/88 (13%)
Query 257 VRIEKARDIPLGATVRNEMDS---------VIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
VRIEK + + + ++R+ G A S LL GD++L+ NG
Sbjct 1402 VRIEKNPGLGFSISGGISGQGNPFKPSDKGIFVTRVQPDGPA--SNLLQPGDKILQANGH 1459
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ + LL T+ V+
Sbjct 1460 SFVHMEHEKAVLLLKSFQNTVDLVIQRE 1487
>sp|Q80TE7|LRRC7_MOUSE Leucine-rich repeat-containing protein
7 OS=Mus musculus OX=10090 GN=Lrrc7 PE=1 SV=2
Length=1490
Score = 59.3 bits (142), Expect = 1e-07, Method: Composition-based stats.
Identities = 20/88 (23%), Positives = 33/88 (38%), Gaps = 11/88 (13%)
Query 257 VRIEKARDIPLGATVRNEMDS---------VIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
VRIEK + + + ++R+ G A S LL GD++L+ NG
Sbjct 1402 VRIEKNPGLGFSISGGISGQGNPFKPSDKGIFVTRVQPDGPA--SNLLQPGDKILQANGH 1459
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ + LL T+ V+
Sbjct 1460 SFVHMEHEKAVLLLKSFQNTVDLVIQRE 1487
>sp|Q6AYQ0|MAGIX_RAT PDZ domain-containing protein MAGIX OS=Rattus
norvegicus OX=10116 GN=Magix PE=2 SV=1
Length=326
Score = 57.8 bits (138), Expect = 1e-07, Method: Composition-based stats.
Identities = 27/128 (21%), Positives = 49/128 (38%), Gaps = 6/128 (5%)
Query 224 HDKVAEQEMQLEPITDERVYESIGQYGGETVKI--VRIEKA-RDIPLGATVRNEMDS--- 277
H + Q ++EP+ + S + V + + L + +
Sbjct 94 HQRSDTQGPRMEPLPVIQNKASYASRLPQATGRFSVELVRGPAGFGLTLSGGRNVSGNVP 153
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
+ + ++K G A++ G L GD VL ING RG + + + L VL Q+
Sbjct 154 LAVCGLLKDGPAQRCGHLQAGDLVLYINGQSTRGLTHAQAVEWIRTGGPRLCLVLQRPQE 213
Query 338 IKPPPAKE 345
+ +KE
Sbjct 214 MNGSRSKE 221
>sp|P51140|DSH_DROME Segment polarity protein dishevelled OS=Drosophila
melanogaster OX=7227 GN=dsh PE=1 SV=2
Length=623
Score = 58.5 bits (140), Expect = 1e-07, Method: Composition-based stats.
Identities = 32/178 (18%), Positives = 58/178 (33%), Gaps = 38/178 (21%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS---D 323
+G + R + + I+KGGA G + GD +L++N + +E +L
Sbjct 268 VGQSNRGGDGGIYVGSIMKGGAVALDGRIEPGDMILQVNDVNFENMTNDEAVRVLREVVQ 327
Query 324 MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVIS 383
G + V+ P + + P +P P
Sbjct 328 KPGPIKLVVAKC----WDPNPKGYFTI-------PRTEPVRPI----------------- 359
Query 384 QEDPNWWQAYREGDEDNQPLAGLV--PGKSFQQQ---REAMKQTIEEDKEPEKSGKLW 436
DP W A+ + + + + P K Q E +K + D E ++W
Sbjct 360 --DPGAWVAHTQALTSHDSIIADIAEPIKERLDQNNLEEIVKAMTKPDSGLEIRDRMW 415
>sp|Q8CIS0|CAR11_MOUSE Caspase recruitment domain-containing protein
11 OS=Mus musculus OX=10090 GN=Card11 PE=1 SV=2
Length=1159
Score = 58.9 bits (141), Expect = 1e-07, Method: Composition-based stats.
Identities = 75/479 (16%), Positives = 151/479 (32%), Gaps = 92/479 (19%)
Query 271 VRNEMDSVIISRIVKGGAAEKSGLLHEGDEVL--------EINGIEIRGKDVNEVFDLLS 322
+ I + G AE++G L EG ++L E + + E +
Sbjct 688 LGGNARGSFIHSVKPGSLAERAG-LREGHQLLLLEGCIRGERQSVPLDACTKEEARWTIQ 746
Query 323 DMHGTLTFVLIPSQQIKPPPAKE---------TVIHVKAHFDYDPSDDPYVPCRELGLSF 373
G +T + + KE +++ + + D +S
Sbjct 747 RCSGLITLHYKVNHEGYRKLLKEMEDGLITSGDSFYIRLNLNISSQLDAC------SMSL 800
Query 374 QKGDILHVIS---QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQ----REAMKQTIEED 426
+ D++HV+ Q+ W A + D G +P S QQ +
Sbjct 801 KCDDVVHVLDTMYQDRHEWLCARVDPFTDQDLDTGTIPSYSRAQQLLLVKLQRLVHRGNR 860
Query 427 KEPEKSGKLWCAKKNKKKRKKVLY---------NANKNDDYDNEEILTYEEMSLYHQPAN 477
+E + + + +N + +++L + + + + Y + +
Sbjct 861 EEADSAHHTLRSLRNTLQPEEMLSTSDPRVSPRLSRASFFFGQLLQFVSRSENKYKRMNS 920
Query 478 RKRPIILIG-PQNC-GQNEL-RQRLMNKE-----------------KDRFASAVPHTTRS 517
+R I+ G P ++ L +L+ ++ A R
Sbjct 921 NERVRIISGSPLGSLSRSSLDATKLLTEKHEELDPENELSRNLTLIPYSLVRAFHCERRR 980
Query 518 R-------------RDQEVAGRDYHF-------VSRQAFEADIAAGKFIEHGEFEKNLYG 557
+ +G F V+R F I E N +
Sbjct 981 PVLFTPTMLAKTLVQKLLNSGGAMEFTICKSDIVTRDEFLRKQKTETIIYSREKNPNTFE 1040
Query 558 TSIDS-VRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA--PPSQERLRALLAKEGK 614
+ + + V K CLL ++ L + P ++ I + +R R LL +
Sbjct 1041 CIVPANIEAVAAKNKHCLLEAGIGCVRDLIKCKVYPIVLLIRVSEKNIKRFRKLLPR--- 1097
Query 615 NPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL----INKLDTEPQWV 669
P+ EE + + +E E A V +++ + +ELLR+ I + + WV
Sbjct 1098 -PETEEEFLRVCRLKEKELEALPCL-YATVEAEMWSSVEELLRVLKDKIVEEQRKTIWV 1154
>sp|O35889|AFAD_RAT Afadin OS=Rattus norvegicus OX=10116 GN=Afdn
PE=1 SV=1
Length=1829
Score = 58.9 bits (141), Expect = 1e-07, Method: Composition-based stats.
Identities = 43/272 (16%), Positives = 91/272 (33%), Gaps = 50/272 (18%)
Query 106 TEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKI 165
++G+ L + + +I++ L + K++ + + S L +Q Q +
Sbjct 838 EKQGLELAADCHLSRIVQATTLLTMDKYVPDDIPNINS---TCFKLNSLQ---LQALLQN 891
Query 166 HNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQ-ELTALLNTPHI------- 217
++ ++ P LI N +A+ L ++ Q E L P +
Sbjct 892 YHCAP---DEPFIPTDLIENVVAVAENTADELARSDGRDVQLEEDPDLQLPFLLPEDGYS 948
Query 218 --------QALLLAHDKVAEQEM-QLEP--------------------ITDERVYESIGQ 248
L D + ++ +L P + E +
Sbjct 949 CDVVRNIPNGLQEFLDPLCQRGFCRLVPHTRSPGTWTIYFEGADYESHLMRENTELTQPL 1008
Query 249 YGGETVKIVRIEKARDIPLGATV----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEI 304
V V ++K + L + + + +VKGGAA+ G L GD++L +
Sbjct 1009 RKEPEVITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1068
Query 305 NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQ 336
+G + G +L++ +T +
Sbjct 1069 DGRSLVGLSQERAAELMTRTSSVVTLEVAKQG 1100
>sp|Q9V9S7|SYDE_DROME Rho GTPase-activating protein 100F OS=Drosophila
melanogaster OX=7227 GN=RhoGAP100F PE=1 SV=2
Length=1866
Score = 58.9 bits (141), Expect = 2e-07, Method: Composition-based stats.
Identities = 25/81 (31%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
Query 253 TVKIVRIEKARDIPLGATVR-----NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
TV++V I K LG +R + D V ISRI A SG L GDE+L +N +
Sbjct 176 TVQLVEIVKRPGQTLGLYIREGNGADRTDGVFISRIALESAVYNSGCLRVGDEILAVNLV 235
Query 308 EIRGKDVNEVFDLLSDMHGTL 328
++ +++V ++S +
Sbjct 236 DVTHMSLDDVVIIMSIPRRLV 256
>sp|E3J0E1|PHNN_PSEI1 Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Pseudofrankia inefficax (strain DSM 45817 / CECT 9037
/ DDB 130130 / EuI1c) OX=298654 GN=phnN PE=3 SV=1
Length=190
Score = 55.4 bits (132), Expect = 2e-07, Method: Composition-based stats.
Identities = 36/192 (19%), Positives = 60/192 (31%), Gaps = 23/192 (12%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+ ++G G++ LM ++R + R G D+ V+ + F A
Sbjct 11 VAVVGASGVGKD----ALMAYARERSEAVAHFPRRVITRPSGPGEDHEPVTEEQFTAARE 66
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKI------CLLSLRTQSLKTLRNSDLKPYII 595
G+ YG + V + +L R L +
Sbjct 67 RGELAVWWPAHGLRYGIPASADVAVGAGRVVVANVSRAVLD-ELAG----RYQRLVVVRV 121
Query 596 FIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNS-DLDKAYQE 654
+ S E L G+ P+P + + + GH DT I N L +
Sbjct 122 TV---SDEVRAQRLRARGREPEPGIGQRL----ARPDPAPGHQADTVIQNDGTLADGGDQ 174
Query 655 LLRLINKLDTEP 666
LLR+I P
Sbjct 175 LLRVILDAAGAP 186
>sp|P27447|YES_XIPHE Tyrosine-protein kinase Yes OS=Xiphophorus
hellerii OX=8084 GN=yes PE=2 SV=3
Length=544
Score = 58.1 bits (139), Expect = 2e-07, Method: Composition-based stats.
Identities = 24/132 (18%), Positives = 40/132 (30%), Gaps = 24/132 (18%)
Query 325 HGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ 384
+ +F + P V A +DY+ LSF+KGD +I+
Sbjct 72 GASTSFTSVTVNNPFPAVITGGVTFFVALYDYEARTSDD-------LSFRKGDRFQIINN 124
Query 385 EDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKK 444
+ +WW+A N G +P + W K +K
Sbjct 125 TEGDWWEARSI----NTGENGYIPSNYVA-------------PADSIQSEEWYFGKLSRK 167
Query 445 RKKVLYNANKND 456
+ L N+
Sbjct 168 DTERLLLLPGNE 179
>sp|P46108|CRK_HUMAN Adapter molecule crk OS=Homo sapiens OX=9606
GN=CRK PE=1 SV=2
Length=304
Score = 57.0 bits (136), Expect = 2e-07, Method: Composition-based stats.
Identities = 24/94 (26%), Positives = 46/94 (49%), Gaps = 16/94 (17%)
Query 329 TFVLIPSQQIKPPP----AKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ 384
T ++ P + + +E +V+A FD++ +D+ +P F+KGDIL + +
Sbjct 112 TTLIEPVSRSRQGSGVILRQEEAEYVRALFDFNGNDEEDLP-------FKKGDILRIRDK 164
Query 385 EDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREA 418
+ WW A ED++ G++P ++ R A
Sbjct 165 PEEQWWNA-----EDSEGKRGMIPVPYVEKYRPA 193
>sp|Q63768|CRK_RAT Adapter molecule crk OS=Rattus norvegicus OX=10116
GN=Crk PE=1 SV=1
Length=304
Score = 57.0 bits (136), Expect = 2e-07, Method: Composition-based stats.
Identities = 24/94 (26%), Positives = 46/94 (49%), Gaps = 16/94 (17%)
Query 329 TFVLIPSQQIKPPP----AKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ 384
T ++ P + + +E +V+A FD++ +D+ +P F+KGDIL + +
Sbjct 112 TTLIEPVSRSRQGSGVILRQEEAEYVRALFDFNGNDEEDLP-------FKKGDILRIRDK 164
Query 385 EDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREA 418
+ WW A ED++ G++P ++ R A
Sbjct 165 PEEQWWNA-----EDSEGKRGMIPVPYVEKYRPA 193
>sp|Q9QZQ1|AFAD_MOUSE Afadin OS=Mus musculus OX=10090 GN=Afdn
PE=1 SV=3
Length=1820
Score = 58.5 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 42/272 (15%), Positives = 91/272 (33%), Gaps = 50/272 (18%)
Query 106 TEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKI 165
++G+ L + + +I++ L + K++ + + S L +Q Q +
Sbjct 831 EKQGLELAADCHLSRIVQATTLLTMDKYVPDDIPNINS---TCFKLNSLQ---LQALLQN 884
Query 166 HNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQ-ELTALLNTPHI------- 217
++ ++ P LI N +A+ L ++ Q E L P +
Sbjct 885 YHCAP---DEPFIPTDLIENVVAVAENTADELARSDGRDVQLEEDPDLQLPFLLPEDGYS 941
Query 218 --------QALLLAHDKVAEQEM-QLEP--------------------ITDERVYESIGQ 248
L D + ++ +L P + E +
Sbjct 942 CDVVRNIPNGLQEFLDPLCQRGFCRLVPHTRSPGTWTIYFEGADYESHLMRENAELAQPL 1001
Query 249 YGGETVKIVRIEKARDIPLGATV----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEI 304
+ V ++K + L + + + +VKGGAA+ G L GD++L +
Sbjct 1002 RKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1061
Query 305 NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQ 336
+G + G +L++ +T +
Sbjct 1062 DGRSLVGLSQERAAELMTRTSSVVTLEVAKQG 1093
>sp|P05433|GAGC_AVISC P47(GAG-CRK) protein OS=Avian sarcoma virus
CT10 OX=11878 PE=4 SV=1
Length=440
Score = 57.8 bits (138), Expect = 2e-07, Method: Composition-based stats.
Identities = 25/94 (27%), Positives = 44/94 (47%), Gaps = 16/94 (17%)
Query 329 TFVLIPSQQIKPPP----AKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ 384
T ++ P + + +E V +V+A FD+ +DD +P F+KGDIL + +
Sbjct 348 TTLIEPVSRSRQNSGVILRQEEVEYVRALFDFKGNDDGDLP-------FKKGDILKIRDK 400
Query 385 EDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREA 418
+ WW A ED G++P ++ R +
Sbjct 401 PEEQWWNA-----EDMDGKRGMIPVPYVEKCRPS 429
>sp|E9Q9W7|PDZD7_MOUSE PDZ domain-containing protein 7 OS=Mus
musculus OX=10090 GN=Pdzd7 PE=1 SV=2
Length=1021
Score = 58.1 bits (139), Expect = 2e-07, Method: Composition-based stats.
Identities = 21/88 (24%), Positives = 42/88 (48%), Gaps = 4/88 (5%)
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHE 297
+ + VR+EK+ LG +VR + + +S++ +G +AE++G L
Sbjct 71 NSPIEANSDESDIIHAVRVEKSPSGRLGFSVRGGSEHGLGIFVSKVEEGSSAERAG-LCV 129
Query 298 GDEVLEINGIEIRGKDVNEVFDLLSDMH 325
GD++ E+NG+ + + LL+
Sbjct 130 GDKITEVNGLSLESTTMGSAVRLLTSSS 157
Score = 55.8 bits (133), Expect = 1e-06, Method: Composition-based stats.
Identities = 19/89 (21%), Positives = 41/89 (46%), Gaps = 6/89 (7%)
Query 254 VKIVRIEK-ARDIPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+IV + + D LG +R + + +S++ GG AE++G + GD+VL NG+
Sbjct 208 RRIVHLYTTSDDFCLGFNIRGGKEFGLGIYVSKVDHGGLAEENG-IKVGDQVLAANGVRF 266
Query 310 RGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
++ ++L + + + +
Sbjct 267 DDISHSQAVEVLKGQTH-IMLTIKETGRY 294
>sp|Q3T0X8|NHRF3_BOVIN Na(+)/H(+) exchange regulatory cofactor
NHE-RF3 OS=Bos taurus OX=9913 GN=PDZK1 PE=2 SV=1
Length=520
Score = 57.8 bits (138), Expect = 2e-07, Method: Composition-based stats.
Identities = 23/118 (19%), Positives = 48/118 (41%), Gaps = 2/118 (2%)
Query 216 HIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARD-IPLGATVRNE 274
+ Q+ L + V E + E+ + G K+ R+ + D
Sbjct 337 YYQSQELPNGSVKEVPAPTPAPLEVSSPETTEEVGDHKPKLCRLARGEDGYGFHLNAVRG 396
Query 275 MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ + KGG A+ +G L + D ++E+NG+ + + +V D + T+T ++
Sbjct 397 QPGSFVKEVQKGGPADLAG-LEDEDVIIEVNGVNMLDESYEKVVDRIQSSGKTVTLLV 453
Score = 55.4 bits (132), Expect = 1e-06, Method: Composition-based stats.
Identities = 24/111 (22%), Positives = 47/111 (42%), Gaps = 1/111 (1%)
Query 260 EKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFD 319
++ + + D ++ I KG AEK+G L +GD VL ING+ + ++ +V D
Sbjct 15 QEGNSYGFFLRIEKDTDGHLVRVIEKGSPAEKAG-LQDGDRVLRINGVFVDKEEHMQVVD 73
Query 320 LLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELG 370
L+ ++T +++ + K+ + +D P G
Sbjct 74 LVRKSGNSVTLLVLDGDSYEKAMKKQVDLKALGQSQEPSLNDKKAPSVMNG 124
Score = 50.4 bits (119), Expect = 4e-05, Method: Composition-based stats.
Identities = 30/188 (16%), Positives = 72/188 (38%), Gaps = 12/188 (6%)
Query 192 EVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIG---Q 248
+V +++ + L L + +A+ D A + Q + D++ + Q
Sbjct 70 QVVDLVRKSGNS--VTLLVLDGDSYEKAMKKQVDLKALGQSQEPSLNDKKAPSVMNGGAQ 127
Query 249 YGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIE 308
+ +++ + V ++ I G A K+G+L + D ++E+NG
Sbjct 128 MWMQPRLCYLVKEGGSYGFSLKTVQGKNGVYMTDIKPQGVAMKAGVLAD-DHLIEVNGEN 186
Query 309 IRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRE 368
+ EV + + +TF+L+ + K ++ + + + +PC+
Sbjct 187 VEDASHEEVVEKVKKSGSRVTFLLVDKETDKHHSEQKIKV------KRETASLKLLPCQP 240
Query 369 LGLSFQKG 376
+ +KG
Sbjct 241 RVVEMKKG 248
>sp|Q9Z0J4|NOS1_MOUSE Nitric oxide synthase 1 OS=Mus musculus
OX=10090 GN=Nos1 PE=1 SV=1
Length=1429
Score = 58.1 bits (139), Expect = 2e-07, Method: Composition-based stats.
Identities = 30/103 (29%), Positives = 46/103 (45%), Gaps = 2/103 (2%)
Query 248 QYGGETVKIVRIEKARDIPLGATVRNEM--DSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
Q V VR+ K + LG V+ + VIIS +++GGAAE+SGL+ GD +L +N
Sbjct 9 QQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVN 68
Query 306 GIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVI 348
+ + ++L + VLI ET
Sbjct 69 DRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTF 111
>sp|P29476|NOS1_RAT Nitric oxide synthase 1 OS=Rattus norvegicus
OX=10116 GN=Nos1 PE=1 SV=1
Length=1429
Score = 58.1 bits (139), Expect = 2e-07, Method: Composition-based stats.
Identities = 30/103 (29%), Positives = 46/103 (45%), Gaps = 2/103 (2%)
Query 248 QYGGETVKIVRIEKARDIPLGATVRNEM--DSVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
Q V VR+ K + LG V+ + VIIS +++GGAAE+SGL+ GD +L +N
Sbjct 9 QQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQAGDIILAVN 68
Query 306 GIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVI 348
+ + ++L + VLI ET
Sbjct 69 DRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTF 111
>sp|O96018|APBA3_HUMAN Amyloid-beta A4 precursor protein-binding
family A member 3 OS=Homo sapiens OX=9606 GN=APBA3 PE=1 SV=1
Length=575
Score = 57.8 bits (138), Expect = 2e-07, Method: Composition-based stats.
Identities = 21/86 (24%), Positives = 39/86 (45%), Gaps = 5/86 (6%)
Query 252 ETVKIVRIEKARDIPLGATV-----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEING 306
+ + V +EK R LG + + + + +I+ ++ GG AE+SG L GD + ING
Sbjct 390 DNCREVHLEKRRGEGLGVALVESGWGSLLPTAVIANLLHGGPAERSGALSIGDRLTAING 449
Query 307 IEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ G + + + + L
Sbjct 450 TSLVGLPLAACQAAVRETKSQTSVTL 475
Score = 55.1 bits (131), Expect = 2e-06, Method: Composition-based stats.
Identities = 17/72 (24%), Positives = 38/72 (53%), Gaps = 1/72 (1%)
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
II +++GG AE+ G + G ++EING + + +LL++ +G + +P+
Sbjct 505 IICSLLRGGIAER-GGIRVGHRIIEINGQSVVATPHARIIELLTEAYGEVHIKTMPAATY 563
Query 339 KPPPAKETVIHV 350
+ +E +++
Sbjct 564 RLLTGQEQPVYL 575
>sp|Q64010|CRK_MOUSE Adapter molecule crk OS=Mus musculus OX=10090
GN=Crk PE=1 SV=1
Length=304
Score = 56.6 bits (135), Expect = 2e-07, Method: Composition-based stats.
Identities = 22/76 (29%), Positives = 40/76 (53%), Gaps = 12/76 (16%)
Query 343 AKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQP 402
+E +V+A FD++ +D+ +P F+KGDIL + + + WW A ED++
Sbjct 130 RQEEAEYVRALFDFNGNDEEDLP-------FKKGDILRIRDKPEEQWWNA-----EDSEG 177
Query 403 LAGLVPGKSFQQQREA 418
G++P ++ R A
Sbjct 178 KRGMIPVPYVEKYRPA 193
>sp|Q71M21|RH21B_XENLA Rho GTPase-activating protein 21-B OS=Xenopus
laevis OX=8355 GN=arhgap21-b PE=2 SV=1
Length=1902
Score = 58.1 bits (139), Expect = 2e-07, Method: Composition-based stats.
Identities = 21/84 (25%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
MD++ + ++ +GG A ++G L GD ++++NG + GK ++V L+ + TL +
Sbjct 100 EPMDTIFVKQVKEGGPAHEAG-LCTGDRIIKVNGESVIGKTYSQVIALIQNSDSTLELSV 158
Query 333 IPSQQIKPPPAKETVIHVKAHFDY 356
+P + A ++K + Y
Sbjct 159 MPKDEDILQLAYSQDAYLKGNDSY 182
>sp|A6QLK6|GRAP_BOVIN GRB2-related adapter protein OS=Bos taurus
OX=9913 GN=GRAP PE=2 SV=1
Length=217
Score = 55.4 bits (132), Expect = 3e-07, Method: Composition-based stats.
Identities = 21/73 (29%), Positives = 33/73 (45%), Gaps = 7/73 (10%)
Query 336 QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYRE 395
Q +P P +A FD+ D LSF++GDI+ V+ + DP+WW+
Sbjct 149 QDEEPLPKPPRACFAQAQFDFSAQDPSQ-------LSFRRGDIIEVLERLDPSWWRGRLS 201
Query 396 GDEDNQPLAGLVP 408
G P + + P
Sbjct 202 GRIGFFPRSYVQP 214
>sp|Q9JJ40|NHRF3_RAT Na(+)/H(+) exchange regulatory cofactor NHE-RF3
OS=Rattus norvegicus OX=10116 GN=Pdzk1 PE=1 SV=2
Length=523
Score = 57.4 bits (137), Expect = 3e-07, Method: Composition-based stats.
Identities = 22/107 (21%), Positives = 50/107 (47%), Gaps = 1/107 (1%)
Query 260 EKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFD 319
++ ++ + + D ++ I +G AEK+GLL +GD VL ING+ + ++ +V D
Sbjct 15 KEGQNYGFFLRIEKDTDGHLVRVIEEGSPAEKAGLL-DGDRVLRINGVFVDKEEHAQVVD 73
Query 320 LLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPC 366
L+ ++T +++ + + + +P+ + P
Sbjct 74 LVRKSGNSVTLLVLDGDSYEKAVKHQVDLKELDQSPREPALNEKKPD 120
Score = 52.4 bits (124), Expect = 9e-06, Method: Composition-based stats.
Identities = 20/111 (18%), Positives = 48/111 (43%), Gaps = 4/111 (4%)
Query 222 LAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIIS 281
+ A LE E +G + + ++++ + + L A +
Sbjct 348 SVKEAPAPISAPLEA-PGSATTEDVGDHKPKLCRLIKEDDSYGFHLNAIRGQ--PGSFVK 404
Query 282 RIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ +GG A+K+GL +E D ++E+NG ++ + + V + + +T ++
Sbjct 405 EVQQGGPADKAGLENE-DIIIEVNGENVQDEPYDRVVERIKSSGEHVTLLV 454
Score = 52.4 bits (124), Expect = 1e-05, Method: Composition-based stats.
Identities = 34/196 (17%), Positives = 68/196 (35%), Gaps = 17/196 (9%)
Query 179 PFPLISNAQDLAQEVQTVL--KPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEP 236
P + A LA + + + V + +E+ + + + L DK + +
Sbjct 165 PQGVAMKAGVLADDHLIEVNGENVENASHEEVVEKVTKSGSRIMFLLVDKETARCHSEQK 224
Query 237 ITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLH 296
+R S+ + +V + + E II I G AE +G L
Sbjct 225 TPFKRETASLKLLPHQPRVVVIKKGSNGYGFYLRAGPEQKGQIIKDIEPGSPAEAAG-LK 283
Query 297 EGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDY 356
D V+ +NG + D + V +++ + T +++ + I+ A F
Sbjct 284 NNDLVVAVNGESVEALDHDGVVEMIRNGGDQTTLLVLDKE--------ADRIYSLARF-- 333
Query 357 DPSDDPYVPCRELGLS 372
P + C+ L
Sbjct 334 ----SPLLYCQSQELP 345
Score = 46.6 bits (109), Expect = 6e-04, Method: Composition-based stats.
Identities = 22/149 (15%), Positives = 55/149 (37%), Gaps = 7/149 (5%)
Query 228 AEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGG 287
+ +E L + + + +++ V ++ I G
Sbjct 108 SPREPALNEKKPDLGMNGGVETCAQPRLCYLVKEGNSFGFSLKTIQGKKGVFLTDITPQG 167
Query 288 AAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV 347
A K+G+L + D ++E+NG + EV + ++ + F+L+ + + ++T
Sbjct 168 VAMKAGVLAD-DHLIEVNGENVENASHEEVVEKVTKSGSRIMFLLVDKETARCHSEQKTP 226
Query 348 IHVKAHFDYDPSDDPYVPCRELGLSFQKG 376
F + + +P + + +KG
Sbjct 227 ------FKRETASLKLLPHQPRVVVIKKG 249
>sp|Q865P3|NHRF3_RABIT Na(+)/H(+) exchange regulatory cofactor
NHE-RF3 OS=Oryctolagus cuniculus OX=9986 GN=PDZK1 PE=1 SV=1
Length=518
Score = 57.4 bits (137), Expect = 3e-07, Method: Composition-based stats.
Identities = 19/118 (16%), Positives = 45/118 (38%), Gaps = 2/118 (2%)
Query 216 HIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKAR-DIPLGATVRNE 274
+ Q+ L + V E + + + K+ R++K
Sbjct 338 YYQSQELPNGSVTEVAAPTPVPPEVSSPDPTEEVEDHKPKLCRLDKGENGYGFHLNAIRG 397
Query 275 MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ + + KG A+ +G L + D ++E+NG+ + + +V D + +T ++
Sbjct 398 LPGSFVKEVQKGSPADLAG-LEDEDIIIEVNGVNVLDEPYEKVVDRIQSSGDNVTLLV 454
Score = 55.1 bits (131), Expect = 2e-06, Method: Composition-based stats.
Identities = 25/114 (22%), Positives = 53/114 (46%), Gaps = 3/114 (3%)
Query 260 EKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFD 319
E+ ++ + + + ++ I KG AEK+G L +GD VL ING+ + ++ +V D
Sbjct 15 EEGQNYGFFLRIEKDTEGHLVRVIEKGSPAEKAG-LQDGDRVLRINGVFVDKEEHMQVVD 73
Query 320 LLSDMHGTLTFVLIPSQQIKPPPAKETVIHV--KAHFDYDPSDDPYVPCRELGL 371
L+ +T +++ + K+ + ++ + D D+ P G+
Sbjct 74 LVRKSGNAVTLLVLDGNSYEKAVKKQVDLKELGQSRQEADLRDENVAPVMNGGV 127
Score = 45.0 bits (105), Expect = 0.002, Method: Composition-based stats.
Identities = 27/144 (19%), Positives = 51/144 (35%), Gaps = 12/144 (8%)
Query 255 KIVRIEK-ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
++ +EK V ++ I+ A K+G+L + D ++E+NG +
Sbjct 134 RLCYLEKQGNSYGFSLKTVQGKKGVYMTDIIPQSVAMKAGVLAD-DHLIEVNGENVEDAS 192
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVI-HVKAHFDYDPSDDPYVPCR--ELG 370
EV + + + F+L+ + K ++ A P V + G
Sbjct 193 HEEVVEKVKKSGNRIVFLLVDKETEKRHSEQKIEFRREAASLKLLPHQPRIVEMKKGSSG 252
Query 371 LSF-------QKGDILHVISQEDP 387
F Q+G I+ I P
Sbjct 253 YGFYLKAGPEQRGQIIKDIDSGSP 276
>sp|Q9JI92|SDCB1_RAT Syntenin-1 OS=Rattus norvegicus OX=10116
GN=Sdcbp PE=1 SV=1
Length=300
Score = 56.2 bits (134), Expect = 3e-07, Method: Composition-based stats.
Identities = 30/199 (15%), Positives = 67/199 (34%), Gaps = 24/199 (12%)
Query 189 LAQEVQTVLK-PVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIG 247
L E+ + + E E +++ Q L+A + + + P+T
Sbjct 51 LYPELSQYMGLSLSEAEICENMPVVSGAPTQGQLVA--RPSSVNYMVAPVT-GNDAGIRR 107
Query 248 QYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
+ ++ V + K +D +G +++ + + + + A G L GD+VL+ING
Sbjct 108 AEIKQGIREVILCKDQDGKIGLRLKSVDNGIFVQLVQANSPASLVG-LRFGDQVLQINGE 166
Query 308 EIRGKDVNEVFDLLSDM-HGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPC 366
G ++ +L +T + + +
Sbjct 167 NCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTVTMHKDS------------------S 208
Query 367 RELGLSFQKGDILHVISQE 385
+G F+ G I ++
Sbjct 209 GHVGFIFKSGKITSIVKDS 227
Score = 47.4 bits (111), Expect = 3e-04, Method: Composition-based stats.
Identities = 23/102 (23%), Positives = 46/102 (45%), Gaps = 5/102 (5%)
Query 255 KIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
+ V + K +G ++ I+ IVK +A ++GLL + EING + G
Sbjct 199 RTVTMHKDSSGHVGFIFKSGK----ITSIVKDSSAARNGLL-TDHHICEINGQNVIGLKD 253
Query 315 NEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDY 356
++ D+LS +T ++P+ + + +K+ D+
Sbjct 254 AQIADILSTAGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDH 295
>sp|Q6DFG0|RH21A_XENLA Rho GTPase-activating protein 21-A OS=Xenopus
laevis OX=8355 GN=arhgap21-a PE=2 SV=1
Length=1926
Score = 57.8 bits (138), Expect = 3e-07, Method: Composition-based stats.
Identities = 21/84 (25%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
MD++ + ++ +GG A ++G L GD ++++NG + GK ++V L+ + TL +
Sbjct 100 EPMDTIFVKQVKEGGPAHEAG-LCTGDRIIKVNGESVIGKTYSQVIALIQNSDSTLELSV 158
Query 333 IPSQQIKPPPAKETVIHVKAHFDY 356
+P + A ++K + Y
Sbjct 159 MPKDEDILQLAYSQDAYLKGNDSY 182
>sp|A2RUV4|RHG21_XENTR Rho GTPase-activating protein 21 OS=Xenopus
tropicalis OX=8364 GN=arhgap21 PE=2 SV=1
Length=1935
Score = 57.8 bits (138), Expect = 3e-07, Method: Composition-based stats.
Identities = 21/84 (25%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
MD++ + ++ +GG A ++G L GD ++++NG + GK ++V L+ + TL +
Sbjct 101 EPMDTIFVKQVKEGGPAHEAG-LCTGDRIIKVNGESVIGKTYSQVIALIQNSDSTLELSV 159
Query 333 IPSQQIKPPPAKETVIHVKAHFDY 356
+P + A ++K + Y
Sbjct 160 MPKDEDILQLAYSQDAYLKGNDSY 183
>sp|Q96RT1|ERBIN_HUMAN Erbin OS=Homo sapiens OX=9606 GN=ERBIN
PE=1 SV=2
Length=1412
Score = 57.8 bits (138), Expect = 3e-07, Method: Composition-based stats.
Identities = 21/110 (19%), Positives = 41/110 (37%), Gaps = 11/110 (10%)
Query 235 EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRN---------EMDSVIISRIVK 285
P T G + VR+EK ++ + + D + ++R+
Sbjct 1302 PPYTQPHCSPRQGHELAKQEIRVRVEKDPELGFSISGGVGGRGNPFRPDDDGIFVTRVQP 1361
Query 286 GGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
G A K LL GD++++ NG + + LL T+ +++
Sbjct 1362 EGPASK--LLQPGDKIIQANGYSFINIEHGQAVSLLKTFQNTVELIIVRE 1409
>sp|Q8R4T5|GRASP_RAT General receptor for phosphoinositides 1-associated
scaffold protein OS=Rattus norvegicus OX=10116 GN=Tamalin
PE=1 SV=1
Length=394
Score = 56.6 bits (135), Expect = 4e-07, Method: Composition-based stats.
Identities = 21/125 (17%), Positives = 50/125 (40%), Gaps = 12/125 (10%)
Query 244 ESIGQYGGETVKIVRIEKARDIPLGATVR------NEMDSV----IISRIVKGGAAEKSG 293
++ Q + K++ +EK + G ++ E V + R+ + A+ +G
Sbjct 88 KNFTQSPEQQRKVLTLEKGDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAG 147
Query 294 LLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVK-A 352
L GD + +NG+ + G E+ D++ L + I+ + + ++K
Sbjct 148 -LTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLRLETLYGTSIRKAELEARLQYLKQT 206
Query 353 HFDYD 357
++
Sbjct 207 LYEKW 211
>sp|P55196|AFAD_HUMAN Afadin OS=Homo sapiens OX=9606 GN=AFDN PE=1
SV=3
Length=1824
Score = 57.4 bits (137), Expect = 4e-07, Method: Composition-based stats.
Identities = 46/272 (17%), Positives = 94/272 (35%), Gaps = 50/272 (18%)
Query 106 TEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKI 165
++G+ L + + +I++ L + K+ + + S L +Q Q +
Sbjct 831 EKQGLELAADCHLSRIVQATTLLTMDKYAPDDIPNINS---TCFKLNSLQ---LQALLQN 884
Query 166 HNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQ-ELTALLNTPHI------- 217
++ ++ P LI N +A+ L +E Q E L P +
Sbjct 885 YHCAP---DEPFIPTDLIENVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYS 941
Query 218 --------QALLLAHDKVAEQEM-QLEPIT----------DERVYES----IGQYGGETV 254
L D + ++ +L P T + YES + +
Sbjct 942 CDVVRNIPNGLQEFLDPLCQRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPL 1001
Query 255 K------IVRIEKARDIPLGATV----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEI 304
+ V ++K + L + + + +VKGGAA+ G L GD++L +
Sbjct 1002 RKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1061
Query 305 NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQ 336
+G + G +L++ +T +
Sbjct 1062 DGRSLVGLSQERAAELMTRTSSVVTLEVAKQG 1093
>sp|E7RAI2|SHO1_OGAPD High osmolarity signaling protein SHO1 OS=Ogataea
parapolymorpha (strain ATCC 26012 / BCRC 20466 / JCM
22074 / NRRL Y-7560 / DL-1) OX=871575 GN=SHO1 PE=3 SV=1
Length=282
Score = 55.4 bits (132), Expect = 5e-07, Method: Composition-based stats.
Identities = 23/78 (29%), Positives = 32/78 (41%), Gaps = 11/78 (14%)
Query 336 QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYRE 395
+ P + I V+ FDYD S D LSF+KGDI V NWWQ
Sbjct 213 NRASALPEDDYPITVRGLFDYDASPDDI-----NELSFKKGDIFRVKDTV-GNWWQGK-- 264
Query 396 GDEDNQPLAGLVPGKSFQ 413
+++ G+ P +
Sbjct 265 ---NSKGEIGMCPSNYLE 279
>sp|O62677|IL16_SAISC Pro-interleukin-16 OS=Saimiri sciureus OX=9521
GN=IL16 PE=2 SV=1
Length=627
Score = 56.6 bits (135), Expect = 5e-07, Method: Composition-based stats.
Identities = 23/129 (18%), Positives = 52/129 (40%), Gaps = 16/129 (12%)
Query 200 VHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRI 259
+ GQ + +LL++ ++ L+ + ++ Q V I+
Sbjct 368 SSPQSGQSVISLLSSEELKQLIEE--------------VKDLDEATLKQLDSIHVTILHK 413
Query 260 EKARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
E+ + ++++ + + R+ G A + G + +G+EVL ING ++G N+
Sbjct 414 EEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHNDA 473
Query 318 FDLLSDMHG 326
+L
Sbjct 474 LAILRQARE 482
Score = 48.9 bits (115), Expect = 1e-04, Method: Composition-based stats.
Identities = 52/250 (21%), Positives = 88/250 (35%), Gaps = 19/250 (8%)
Query 112 LESPHYAVKILEIEDLFS-SLKHIQHTLVDSQSQED-ISLLLQLVQNKDFQNAFKIHNAI 169
L S I E++DL +LK + V +E+ L L D +N K+
Sbjct 380 LSSEELKQLIEEVKDLDEATLKQLDSIHVTILHKEEGAGLGFSLAGGADLEN--KVITVH 437
Query 170 TVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAE 229
V N + I ++ LK H + + P QA+++ E
Sbjct 438 RVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHNDALAILRQAREPR-QAVIVTRKLTPE 496
Query 230 QEMQL------EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD------S 277
L S+ TV V +EK LG ++
Sbjct 497 TVPDLNSSTDSAASASAASDVSVDSTAEATVCTVTLEKMSG-GLGFSLEGGKGSLQGDKP 555
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD-MHGTLTFVLIPSQ 336
+ I+RI KG A+E+S + GDE+L + G ++G E ++++ G +T V+
Sbjct 556 LTINRIFKGAASEQSETVQPGDEILHLAGTAMQGLTRFEAWNIIKALPDGPVTIVIKRKS 615
Query 337 QIKPPPAKET 346
+
Sbjct 616 MQSKGTSAAG 625
>sp|O70248|APBA3_RAT Amyloid-beta A4 precursor protein-binding
family A member 3 OS=Rattus norvegicus OX=10116 GN=Apba3 PE=1
SV=2
Length=569
Score = 56.6 bits (135), Expect = 5e-07, Method: Composition-based stats.
Identities = 52/265 (20%), Positives = 94/265 (35%), Gaps = 29/265 (11%)
Query 84 SMRLKKLAQIPPKT--GIDNPMFDTEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDS 141
S +L PP T G D + E+ D+F S K ++ DS
Sbjct 223 STQLLSERNPPPSTRMGQAQEAMDRVKAPEGETQPMTEV-----DIFISTKRVKVLAADS 277
Query 142 QSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVH 201
Q + + Q I + V + A + +QD +++ +L V
Sbjct 278 Q---------DALMDHALQTISYIADIGPVLVLMARRRLAKRTTSQDRQRQLYKMLCHVF 328
Query 202 HKEGQELT-----ALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQY-GGETVK 255
H E +L + + Q L ++ MQ + + + +
Sbjct 329 HSEDAQLIAQAIGQAFSIAYSQFLQENRIDPSQVGMQPSASASHPHNGDLDHFCNSQNCR 388
Query 256 IVRIEKARDIPLGATV-----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
V I+K LG + + + + +I+ ++ GG AE+ G L GD V ING +
Sbjct 389 EVCIQKRPGEGLGVALVESGWGSLLPTAVIANLLHGGPAERCGALSIGDRVTAINGTSLV 448
Query 311 GKDVNEVFDLLSD--MHGTLTFVLI 333
G + + + H ++T +I
Sbjct 449 GLSLAACQAAVREVRRHSSVTLSII 473
Score = 48.5 bits (114), Expect = 2e-04, Method: Composition-based stats.
Identities = 15/72 (21%), Positives = 35/72 (49%), Gaps = 2/72 (3%)
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
II +++G AAE+ G + G ++E+NG + + LL++ + +P+
Sbjct 500 IICSLLRGSAAER-GGVRVGHRIIEVNGQSVVAMPHARIIQLLTETRE-IHIKTMPAATY 557
Query 339 KPPPAKETVIHV 350
+ +E +++
Sbjct 558 RLLTGQEQPVYL 569
>sp|Q2GT05|HSE1_CHAGB Class E vacuolar protein-sorting machinery
protein HSE1 OS=Chaetomium globosum (strain ATCC 6205 / CBS
148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) OX=306901 GN=HSE1
PE=3 SV=1
Length=713
Score = 57.0 bits (136), Expect = 5e-07, Method: Composition-based stats.
Identities = 31/134 (23%), Positives = 58/134 (43%), Gaps = 16/134 (12%)
Query 334 PSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAY 393
P Q + TV V+A +D+ PS+ L F+KGD++ V+ +WW+
Sbjct 214 PIQPMPSGTTAATVSRVRALYDFAPSEPGE-------LEFKKGDVIAVLESVYKDWWRGS 266
Query 394 REGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNAN 453
+G G+ P ++ + ++ E + +++ KN +K +L +N
Sbjct 267 LKGKT------GIFPLNYVEKLTDPTPDELQR--EAQMEAEVFAEIKNVEKLLTLLSASN 318
Query 454 KND-DYDNEEILTY 466
+ DNEEI +
Sbjct 319 TAPREEDNEEISKF 332
>sp|P87378|CRK_XENLA Adapter molecule crk OS=Xenopus laevis OX=8355
GN=crk PE=2 SV=1
Length=296
Score = 55.4 bits (132), Expect = 5e-07, Method: Composition-based stats.
Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 15/91 (16%)
Query 329 TFVLIPSQQIKPPP---AKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE 385
T ++ P + K +E V +++A FD+ +DD +P F+KGDIL + +
Sbjct 106 TTLIEPVSKSKQSGVIQRQEEVEYLRALFDFIGNDDEDLP-------FKKGDILRIREKP 158
Query 386 DPNWWQAYREGDEDNQPLAGLVPGKSFQQQR 416
+ WW A ED+ G++P ++ R
Sbjct 159 EEQWWNA-----EDSDGRRGMIPVPYVEKYR 184
>sp|Q9JJA9|GRASP_MOUSE General receptor for phosphoinositides
1-associated scaffold protein OS=Mus musculus OX=10090 GN=Tamalin
PE=1 SV=2
Length=392
Score = 55.8 bits (133), Expect = 6e-07, Method: Composition-based stats.
Identities = 21/125 (17%), Positives = 50/125 (40%), Gaps = 12/125 (10%)
Query 244 ESIGQYGGETVKIVRIEKARDIPLGATVR------NEMDSV----IISRIVKGGAAEKSG 293
++ Q + K++ +EK + G ++ E V + R+ + A+ +G
Sbjct 88 KNFTQSPEQQRKVLTLEKGDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAG 147
Query 294 LLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVK-A 352
L GD + +NG+ + G E+ D++ L + I+ + + ++K
Sbjct 148 -LTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLRLETLYGTSIRKAELEARLQYLKQT 206
Query 353 HFDYD 357
++
Sbjct 207 LYEKW 211
>sp|Q0QWG9|GRD2I_MOUSE Delphilin OS=Mus musculus OX=10090 GN=Grid2ip
PE=1 SV=1
Length=1203
Score = 57.0 bits (136), Expect = 6e-07, Method: Composition-based stats.
Identities = 22/76 (29%), Positives = 37/76 (49%), Gaps = 3/76 (4%)
Query 257 VRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
VR+ K + G T+R V I ++ G AE + L GD +L +NG+++R ++
Sbjct 269 VRVYKG-NKSFGFTLRGH-GPVWIESVLPGSPAE-NASLKSGDRILFLNGLDMRNCSHDK 325
Query 317 VFDLLSDMHGTLTFVL 332
V +L T V+
Sbjct 326 VVSMLQGSGAMPTLVV 341
Score = 44.3 bits (103), Expect = 0.004, Method: Composition-based stats.
Identities = 14/79 (18%), Positives = 30/79 (38%), Gaps = 3/79 (4%)
Query 265 IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
G + + + +G +A +G L GD++LE+ G+ + G + L
Sbjct 10 EDFGFQLGGS-GPCFVIEVAEGSSAH-AGGLRPGDQILEVEGLAVGGLSRERIVRLARRC 67
Query 325 HGT-LTFVLIPSQQIKPPP 342
+ ++P + P
Sbjct 68 PRVPPSLGVLPGPEGGPTA 86
>sp|Q5RBI7|PDZD7_PONAB PDZ domain-containing protein 7 OS=Pongo
abelii OX=9601 GN=PDZD7 PE=2 SV=2
Length=1005
Score = 56.6 bits (135), Expect = 6e-07, Method: Composition-based stats.
Identities = 29/154 (19%), Positives = 59/154 (38%), Gaps = 12/154 (8%)
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHE 297
+ + VR+EK+ LG +VR + + +S++ +G +AE++G L
Sbjct 71 NSPIEANSDESDIIHSVRVEKSPAGRLGFSVRGGSEHGLGIFVSKVEEGSSAERAG-LCV 129
Query 298 GDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV----LIPSQQIKPPPAKETVIHVKAH 353
GD++ E+NG+ + + +L+ V +P + + +
Sbjct 130 GDKITEVNGLSLESTTMGSAVKVLTGSSRLHMMVRRMGRVPGIKFSKEKTTWVDVVNRRL 189
Query 354 FDYDPSDDPYVPCRELGLSFQKGDILHVISQEDP 387
S P E G+ I+H+ + D
Sbjct 190 VVEKCSSTPSDTSSEDGIR----RIVHLYTTSDD 219
Score = 56.2 bits (134), Expect = 9e-07, Method: Composition-based stats.
Identities = 19/89 (21%), Positives = 41/89 (46%), Gaps = 6/89 (7%)
Query 254 VKIVRIEK-ARDIPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+IV + + D LG +R + + +S++ GG AE++G + GD+VL NG+
Sbjct 208 RRIVHLYTTSDDFCLGFNIRGGKEFGLGIYVSKVDHGGLAEENG-IKVGDQVLAANGVRF 266
Query 310 RGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
++ ++L + + + +
Sbjct 267 DDISHSQAVEVLKGQTH-IMLTIKETGRY 294
>sp|P98084|APBA2_MOUSE Amyloid-beta A4 precursor protein-binding
family A member 2 OS=Mus musculus OX=10090 GN=Apba2 PE=1
SV=2
Length=750
Score = 56.6 bits (135), Expect = 6e-07, Method: Composition-based stats.
Identities = 70/361 (19%), Positives = 135/361 (37%), Gaps = 66/361 (18%)
Query 37 VDCPGDLGTRMMPIRRSAQLERIRQQQEDMRRRREEEGKKQELDLNSSMR------LKKL 90
V PGDL R + + ER + QE + E+ K+Q DLN KK+
Sbjct 291 VKHPGDL-QRGLKTKTRTPEERPKWPQEQVCNGLEQPRKQQRSDLNGPTDNNNIPETKKV 349
Query 91 AQIPPKTGIDNPMFDTE--EGIVL-------------ESPHYAVKILEIEDLFSSLKHIQ 135
A P + P + +GI+ +P +++++ ++ S +K +Q
Sbjct 350 ASFPSFVAVPGPCEAEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQ 409
Query 136 ---------HTLVDSQSQEDISLLLQLVQNKDF----------QNAFKI-----HNAITV 171
++ D+Q+ ++ L + + K I I V
Sbjct 410 KAAKIKKKANSEGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVV 469
Query 172 HMNKASPPFPLISNAQDL---AQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAH---- 224
M + P + + AQE + K + H E L+ QA +A+
Sbjct 470 LMARRRMPRSASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFL 529
Query 225 -------DKVAEQEM-QLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV----- 271
+ ++++E + + + I E K +++EK + LG V
Sbjct 530 RANGINPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGW 589
Query 272 RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV 331
+ + +VI++ ++ GG A +SG L GD+++ ING + G + ++ +
Sbjct 590 GSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVK 649
Query 332 L 332
L
Sbjct 650 L 650
Score = 55.8 bits (133), Expect = 1e-06, Method: Composition-based stats.
Identities = 25/106 (24%), Positives = 49/106 (46%), Gaps = 6/106 (6%)
Query 246 IGQYGGETVKIVRIEK-ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEI 304
+ V V I++ LG +V+N II +++GG AE+ G + G ++EI
Sbjct 650 LNIVSCPPVTTVLIKRPDLKYQLGFSVQNG----IICSLMRGGIAER-GGVRVGHRIIEI 704
Query 305 NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHV 350
NG + ++ LS+ G + +P+ + +ET +++
Sbjct 705 NGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI 750
>sp|Q80TH2|ERBIN_MOUSE Erbin OS=Mus musculus OX=10090 GN=Erbin
PE=1 SV=3
Length=1402
Score = 56.6 bits (135), Expect = 6e-07, Method: Composition-based stats.
Identities = 58/357 (16%), Positives = 116/357 (32%), Gaps = 59/357 (17%)
Query 31 KHREMAVDCPGDLGTRMMPIRRSAQLERIRQQQEDMRRRREEEGKKQELDLNSSMRLKKL 90
+H EM P D R++P ++R + ++ E D S L +
Sbjct 1050 RHGEMWAISPND---RLVPAVTRTTIQRQSSVSSTASVNLGDPTRRTEGDYLSYRELHSM 1106
Query 91 AQIPPKTGIDNPM---FDTEEGIVLESPHYA-VKILEIEDLFSSLKHI------------ 134
+ P +G P+ + +G P A I EI + S+
Sbjct 1107 GRTPVMSGSQRPLSARAYSIDGPNTSRPQSARPSINEIPERTMSVSDFNYSRTSPSKRPN 1166
Query 135 -----QHTLVDSQSQEDISLLLQLVQNKDFQNA-FKIHNAI----------TVHMNKASP 178
+H+L+D + + + + + + H + +
Sbjct 1167 TRVGSEHSLLDPPGKSKVPHDWREQVLRHIEAKKLEKHPQTSSPGECCQDDRFMSEEQNH 1226
Query 179 PFPLISNAQDLAQEVQTVLKPVHHKEGQELT--ALLNTPHI--QALLLAHDKVAE----- 229
P +S+ + L + + + + GQ L A + H QA + H +
Sbjct 1227 PSGALSH-RGLPDSLMKMP-LSNGQMGQPLRPQAHYSQTHHPPQASVARHPSREQLIDYL 1284
Query 230 --QEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRN---------EMDSV 278
+ P T G + VR+EK ++ + + D +
Sbjct 1285 MLKVAHQPPYTHPHCSPRQGHELAKQEIRVRVEKDPELGFSISGGVGGRGNPFRPDDDGI 1344
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
++R+ G A K LL GD++++ NG + + LL H + +++
Sbjct 1345 FVTRVQPEGPASK--LLQPGDKIIQANGYSFINIEHGQAVSLLKTFHNAVDLIIVRE 1399
>sp|Q6C2N2|HSE1_YARLI Class E vacuolar protein-sorting machinery
protein HSE1 OS=Yarrowia lipolytica (strain CLIB 122 / E
150) OX=284591 GN=HSE1 PE=3 SV=1
Length=685
Score = 56.2 bits (134), Expect = 7e-07, Method: Composition-based stats.
Identities = 39/161 (24%), Positives = 71/161 (44%), Gaps = 21/161 (13%)
Query 339 KPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDE 398
P P TV VKA +D + ++ LSF+KGDI+ V+ +WW+ G
Sbjct 244 DPTPTVATVSRVKALYDLNATEPGE-------LSFRKGDIITVLESVFRDWWRGSLRGQV 296
Query 399 DNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLY--NANKND 456
PL ++P A E +KE ++ ++ +N +K +L +A + +
Sbjct 297 GIFPLNYVMP--------IAEPTPAEIEKEAQEELSVFSQSRNIEKLLALLSSQDAARLN 348
Query 457 DYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQ 497
+NEE+ + +L A R + + LI +++L +
Sbjct 349 LAENEELQSLYHSTL----AIRPKLVKLIDKYAQRKDDLVE 385
>sp|Q11C47|PHNN_CHESB Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Chelativorans sp. (strain BNC1) OX=266779 GN=phnN PE=3
SV=1
Length=209
Score = 53.9 bits (128), Expect = 8e-07, Method: Composition-based stats.
Identities = 36/194 (19%), Positives = 72/194 (37%), Gaps = 16/194 (8%)
Query 475 PANRKRPIILIGPQNCGQNELR---QRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFV 531
P + + + GP G++ + + + A TR G ++
Sbjct 16 PIRQGVFVAVAGPSGGGKDSVMAYARERLGNLAGEIVFARRIITRPFAPG---GEEHDTR 72
Query 532 SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTL--RNSD 589
FE + AAG F Y ++ + + SG + + ++ + L R +
Sbjct 73 DVPTFEREEAAGAFALSWRANGLCYALP-AALDEEMRSGGVVVANVSRAIIPALGERYAH 131
Query 590 LKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD-L 648
+ P I+ AP + L L++ G+ + E L + ++ E + I NS L
Sbjct 132 IFPVIV-TAP--RGVLAERLSRRGRETRDEVLSRL-ARSEAGELDVPGA--LVIDNSGPL 185
Query 649 DKAYQELLRLINKL 662
++A + L + K
Sbjct 186 EQAGERFLEALRKA 199
>sp|O88811|STAM2_MOUSE Signal transducing adapter molecule 2 OS=Mus
musculus OX=10090 GN=Stam2 PE=1 SV=1
Length=523
Score = 55.8 bits (133), Expect = 8e-07, Method: Composition-based stats.
Identities = 31/182 (17%), Positives = 64/182 (35%), Gaps = 30/182 (16%)
Query 305 NGIEI-RGKDVNEVFDL----LSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPS 359
NG + + K+ ++ L + T + + V+A +D++
Sbjct 157 NGTSLNKNKEDEDIAKAIELSLQEQKQQYTETKALYPPAESQLNNKAARRVRALYDFEAV 216
Query 360 DDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSF------- 412
+D L+F+ G+++ V+ D NWWQ +N GL P
Sbjct 217 EDNE-------LTFKHGELITVLDDSDANWWQG------ENHRGTGLFPSNFVTTDLSTE 263
Query 413 -----QQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYE 467
+ + +EE K+ E K + + + K D++++L E
Sbjct 264 VETATVDKLNVIDDDVEEIKKSEPEPVYIDEGKMDRALQILQSIDPKESKPDSQDLLDLE 323
Query 468 EM 469
++
Sbjct 324 DV 325
>sp|O54824|IL16_MOUSE Pro-interleukin-16 OS=Mus musculus OX=10090
GN=Il16 PE=1 SV=3
Length=1322
Score = 56.2 bits (134), Expect = 8e-07, Method: Composition-based stats.
Identities = 24/139 (17%), Positives = 55/139 (40%), Gaps = 4/139 (3%)
Query 190 AQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQY 249
E++ + + E ++ Q+++ AE+ +L ++ Q
Sbjct 1044 LSELREYSEGLTEPGETEDRNHCSSQAGQSVISL--LSAEELEKLIEEVRVLDEATLKQL 1101
Query 250 GGETVKIVRIEKARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
V I+ E+ + ++++ + + R+ G A + G + +G+EVL ING
Sbjct 1102 DSIHVTILHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGK 1161
Query 308 EIRGKDVNEVFDLLSDMHG 326
++G N+ +L
Sbjct 1162 SLKGATHNDALAILRQARD 1180
Score = 53.5 bits (127), Expect = 6e-06, Method: Composition-based stats.
Identities = 32/151 (21%), Positives = 56/151 (37%), Gaps = 16/151 (11%)
Query 208 LTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKI---VRIEKARD 264
L + L+ P ++L + P + E S +I V ++K
Sbjct 306 LCSHLSPPLCRSLSSS----TCGAQDSSPFSLES-PASPASTAKPNYRIMVEVSLKKEAG 360
Query 265 IPLGATVRNE-----MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFD 319
+ LG + + + + + + G A G L GDE++EIN + +NEV+
Sbjct 361 VGLGIGLCSIPYFQCISGIFVHTLSPGSVAHLDGRLRCGDEIVEINDSPVHCLTLNEVYT 420
Query 320 LLSDMHGT---LTFVLIPSQQIKPPPAKETV 347
+LS + P Q+ KE V
Sbjct 421 ILSHCDPGPVPIIVSRHPDPQVSEQQLKEAV 451
Score = 50.8 bits (120), Expect = 4e-05, Method: Composition-based stats.
Identities = 23/91 (25%), Positives = 38/91 (42%), Gaps = 6/91 (7%)
Query 257 VRIEKARDIPLGATVRNEMD------SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
+ + K + LG ++ D + + I GGAA G L EGDE+LE+NG +
Sbjct 214 IVLMKGQAKGLGFSIVGGKDSIYGPIGIYVKSIFAGGAAAADGRLQEGDEILELNGESMA 273
Query 311 GKDVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
G + L + + ++ PP
Sbjct 274 GLTHQDALQKFKQAKKGLLTLTVRTRLTTPP 304
Score = 47.0 bits (110), Expect = 7e-04, Method: Composition-based stats.
Identities = 53/272 (19%), Positives = 96/272 (35%), Gaps = 24/272 (9%)
Query 83 SSMRLKKLAQIPPKTGIDNPMFDTEEG---IVLESPHYAVKILEIEDLFS--SLKHIQHT 137
S +R P D ++ G I L S K++E + +LK +
Sbjct 1045 SELREYSEGLTEPGETEDRNHCSSQAGQSVISLLSAEELEKLIEEVRVLDEATLKQLDSI 1104
Query 138 LVDSQSQED-ISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTV 196
V +E+ L L D +N K+ V N + I ++
Sbjct 1105 HVTILHKEEGAGLGFSLAGGADLEN--KVITVHRVFPNGLASQEGTIQKGNEVLSINGKS 1162
Query 197 LKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQL-----EPITDERVYESIGQYGG 251
LK H + + P QA+++ E L + + +
Sbjct 1163 LKGATHNDALAILRQARDPR-QAVIVTRRTTVEATHDLNSSTDSAASASAASDISVESKE 1221
Query 252 ETVKIVRIEKARDIPLGATVRNEMD------SVIISRIVKGGAAEKSGLLHEGDEVLEIN 305
TV V +EK LG ++ + I+RI KG E+ ++ GDE+L++
Sbjct 1222 ATVCTVTLEK-TSAGLGFSLEGGKGSLHGDKPLTINRIFKGT--EQGEMVQPGDEILQLA 1278
Query 306 GIEIRGKDVNEVFDLLSD-MHGTLTFVLIPSQ 336
G ++G E ++++ G +T V+ +
Sbjct 1279 GTAVQGLTRFEAWNVIKALPDGPVTIVIRRTS 1310
>sp|O88888|APBA3_MOUSE Amyloid-beta A4 precursor protein-binding
family A member 3 OS=Mus musculus OX=10090 GN=Apba3 PE=1
SV=1
Length=571
Score = 55.8 bits (133), Expect = 9e-07, Method: Composition-based stats.
Identities = 22/110 (20%), Positives = 46/110 (42%), Gaps = 7/110 (6%)
Query 252 ETVKIVRIEKARDIPLGATV-----RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEING 306
+ + V I+K LG + + + + +I+ ++ GG AE+ G L GD V ING
Sbjct 387 QNCREVCIQKRPGEGLGVALVESGWGSLLPTAVIANLLHGGPAERCGALSIGDRVTAING 446
Query 307 IEIRGKDVNEVFDLLSDMHG--TLTFVLIPSQQIKPPPAKETVIHVKAHF 354
+ G + + ++ ++T +I + + + + F
Sbjct 447 TSLVGLSLAACQAAVREVRRLSSVTLSIIHCPPVTTAVIRRPHVREQLGF 496
Score = 49.7 bits (117), Expect = 7e-05, Method: Composition-based stats.
Identities = 16/72 (22%), Positives = 36/72 (50%), Gaps = 2/72 (3%)
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
II +++GGAAE+ G + G ++E+NG + + LL++ + +P+
Sbjct 502 IICSLLRGGAAER-GGVRVGHRIIEVNGQSVVAMPHARIIQLLTETRE-IHIKTMPAATY 559
Query 339 KPPPAKETVIHV 350
+ +E +++
Sbjct 560 RLLTGQEQPVYL 571
>sp|Q9V9J3|SRC42_DROME Tyrosine-protein kinase Src42A OS=Drosophila
melanogaster OX=7227 GN=Src42A PE=1 SV=1
Length=517
Score = 55.8 bits (133), Expect = 1e-06, Method: Composition-based stats.
Identities = 19/84 (23%), Positives = 30/84 (36%), Gaps = 12/84 (14%)
Query 333 IPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 392
+P I V A +DYD D LSF+KG+ L +++ +WW A
Sbjct 52 VPQIPESETAGANAKIFV-ALYDYDARTDED-------LSFRKGEHLEILNDTQGDWWLA 103
Query 393 YREGDEDNQPLAGLVPGKSFQQQR 416
G +P + +
Sbjct 104 R----SKKTRSEGYIPSNYVAKLK 123
>sp|Q4KL35|MAGIX_MOUSE PDZ domain-containing protein MAGIX OS=Mus
musculus OX=10090 GN=Magix PE=1 SV=1
Length=324
Score = 55.1 bits (131), Expect = 1e-06, Method: Composition-based stats.
Identities = 25/103 (24%), Positives = 38/103 (37%), Gaps = 3/103 (3%)
Query 260 EKARDIPLGATVRNEMDS---VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
L + + + + ++K G A++ G L GD VL ING +G +
Sbjct 133 RGPAGFGLTLSGGRNVSGDAPLTVHGLLKDGPAQRCGRLQAGDLVLYINGQSTQGLTHAQ 192
Query 317 VFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPS 359
V + + L VL Q + KE H K DP
Sbjct 193 VVERIRTGGPHLCLVLQRPQDMDGSRIKEVGGHRKTDRSLDPR 235
>sp|E3HQ85|PHNN_ACHXA Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Achromobacter xylosoxidans (strain A8) OX=762376 GN=phnN
PE=3 SV=1
Length=192
Score = 53.1 bits (126), Expect = 1e-06, Method: Composition-based stats.
Identities = 29/162 (18%), Positives = 54/162 (33%), Gaps = 18/162 (11%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ 534
PA+ R I L+G G++ L + L + + V H R D ++
Sbjct 6 PADGARLIYLMGASGSGKDTLLRLLRAELRGDEPVLVAH--RYITRDSGDTEDALRLTED 63
Query 535 AFEADIAAGKF-IEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK------TLRN 587
F A G F + YG I+ + ++ G ++ + R
Sbjct 64 EFGRRAALGCFALRWAS-HGLQYGIGIE-IDAWLSCGAAVII----NGSRAHLEQAHSRY 117
Query 588 SDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTR 629
L + + P +L LA G+ + + + T+
Sbjct 118 PALTAVEVTVDP---GQLARRLAGRGRESAEQIAQRLARATQ 156
>sp|Q9H5P4|PDZD7_HUMAN PDZ domain-containing protein 7 OS=Homo
sapiens OX=9606 GN=PDZD7 PE=1 SV=2
Length=1033
Score = 55.8 bits (133), Expect = 1e-06, Method: Composition-based stats.
Identities = 20/88 (23%), Positives = 42/88 (48%), Gaps = 4/88 (5%)
Query 241 RVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHE 297
+ + VR+EK+ LG +VR + + +S++ +G +AE++G L
Sbjct 71 NSPIEANSDESDIIHSVRVEKSPAGRLGFSVRGGSEHGLGIFVSKVEEGSSAERAG-LCV 129
Query 298 GDEVLEINGIEIRGKDVNEVFDLLSDMH 325
GD++ E+NG+ + + +L+
Sbjct 130 GDKITEVNGLSLESTTMGSAVKVLTSSS 157
Score = 55.1 bits (131), Expect = 2e-06, Method: Composition-based stats.
Identities = 19/89 (21%), Positives = 41/89 (46%), Gaps = 6/89 (7%)
Query 254 VKIVRIEK-ARDIPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+IV + + D LG +R + + +S++ GG AE++G + GD+VL NG+
Sbjct 208 RRIVHLYTTSDDFCLGFNIRGGKEFGLGIYVSKVDHGGLAEENG-IKVGDQVLAANGVRF 266
Query 310 RGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
++ ++L + + + +
Sbjct 267 DDISHSQAVEVLKGQTH-IMLTIKETGRY 294
>sp|Q0V8R5|IL16_BOVIN Pro-interleukin-16 OS=Bos taurus OX=9913
GN=IL16 PE=2 SV=1
Length=627
Score = 55.4 bits (132), Expect = 1e-06, Method: Composition-based stats.
Identities = 25/146 (17%), Positives = 55/146 (38%), Gaps = 16/146 (11%)
Query 201 HHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIE 260
+ GQ + +LL+T ++ L+ ++ Q V I+ E
Sbjct 370 TSQPGQSVISLLSTEELKKLIEE--------------VKVLDEATLKQLDSIHVTILHKE 415
Query 261 KARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVF 318
+ + ++++ + + R+ G A + G + +G+EVL ING ++G N+
Sbjct 416 EGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGATHNDAL 475
Query 319 DLLSDMHGTLTFVLIPSQQIKPPPAK 344
+L V++ +
Sbjct 476 AILRQAREPRQAVIVTRRPTLEATTD 501
>sp|Q9H6Y5|MAGIX_HUMAN PDZ domain-containing protein MAGIX OS=Homo
sapiens OX=9606 GN=MAGIX PE=1 SV=4
Length=334
Score = 54.7 bits (130), Expect = 1e-06, Method: Composition-based stats.
Identities = 22/89 (25%), Positives = 38/89 (43%), Gaps = 1/89 (1%)
Query 253 TVKIVRIEKARDIPLGATVRNEMD-SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
+V++VR + LG D + + ++K G A++ G L GD VL ING +G
Sbjct 125 SVELVRGYAGFGLTLGGGRDVAGDTPLAVRGLLKDGPAQRCGRLEVGDLVLHINGESTQG 184
Query 312 KDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
+ + + L V+ + P
Sbjct 185 LTHAQAVERIRAGGPQLHLVIRRPLETHP 213
>sp|Q14005|IL16_HUMAN Pro-interleukin-16 OS=Homo sapiens OX=9606
GN=IL16 PE=1 SV=4
Length=1332
Score = 55.8 bits (133), Expect = 1e-06, Method: Composition-based stats.
Identities = 25/139 (18%), Positives = 61/139 (44%), Gaps = 7/139 (5%)
Query 190 AQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQY 249
+E L + + ++L + + +LL + + ++ ++ + DE ++ Q
Sbjct 1054 LREYTEGLTEAKEDDDGDHSSLQSGQSVISLLSSEEL--KKLIEEVKVLDEA---TLKQL 1108
Query 250 GGETVKIVRIEKARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
G V I+ E+ + ++++ + + R+ G A + G + +G+EVL ING
Sbjct 1109 DGIHVTILHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGK 1168
Query 308 EIRGKDVNEVFDLLSDMHG 326
++G ++ +L
Sbjct 1169 SLKGTTHHDALAILRQARE 1187
Score = 53.9 bits (128), Expect = 4e-06, Method: Composition-based stats.
Identities = 29/134 (22%), Positives = 49/134 (37%), Gaps = 10/134 (7%)
Query 218 QALLLAHDKVAEQEMQLEPITDERVYESIGQYGG----ETVKIVRIEKARDIPLGATVRN 273
++L D A + T + Q G + + + K + LG ++
Sbjct 174 KSLSQQLDCPAGKAAGTSRPTRSLSTAQLVQPSGGLQASVISNIVLMKGQAKGLGFSIVG 233
Query 274 EMD------SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGT 327
D + + I GGAA G L EGDE+LE+NG + G +
Sbjct 234 GKDSIYGPIGIYVKTIFAGGAAAADGRLQEGDEILELNGESMAGLTHQDALQKFKQAKKG 293
Query 328 LTFVLIPSQQIKPP 341
L + + ++ PP
Sbjct 294 LLTLTVRTRLTAPP 307
Score = 51.2 bits (121), Expect = 3e-05, Method: Composition-based stats.
Identities = 54/255 (21%), Positives = 91/255 (36%), Gaps = 21/255 (8%)
Query 110 IVLESPHYAVKILEIEDLFS--SLKHIQHTLVDSQSQED-ISLLLQLVQNKDFQNAFKIH 166
I L S K++E + +LK + V +E+ L L D +N K+
Sbjct 1082 ISLLSSEELKKLIEEVKVLDEATLKQLDGIHVTILHKEEGAGLGFSLAGGADLEN--KVI 1139
Query 167 NAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDK 226
V N + I ++ LK H + + P QA+++
Sbjct 1140 TVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHHDALAILRQAREPR-QAVIVTRKL 1198
Query 227 VAEQEMQL------EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---- 276
E L S+ TV V +EK LG ++
Sbjct 1199 TPEAMPDLNSSTDSAASASAASDVSVESTAEATVCTVTLEK-MSAGLGFSLEGGKGSLHG 1257
Query 277 --SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD-MHGTLTFVLI 333
+ I+RI KG A+E+S + GDE+L++ G ++G E ++++ G +T V+
Sbjct 1258 DKPLTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIR 1317
Query 334 PSQ-QIKPPPAKETV 347
Q K A
Sbjct 1318 RKSLQSKETTAAGDS 1332
Score = 48.9 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 24/116 (21%), Positives = 44/116 (38%), Gaps = 11/116 (9%)
Query 243 YESIGQYGGETVKI---VRIEKARDIPLGATVRNE-----MDSVIISRIVKGGAAEKSGL 294
+ +I V ++K + LG + + + + + + G A G
Sbjct 339 PSAPISTAKPNYRIMVEVSLQKEAGVGLGIGLCSVPYFQCISGIFVHTLSPGSVAHLDGR 398
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGT---LTFVLIPSQQIKPPPAKETV 347
L GDE++EI+ + +NEV+ +LS + P Q+ KE V
Sbjct 399 LRCGDEIVEISDSPVHCLTLNEVYTILSHCDPGPVPIIVSRHPDPQVSEQQLKEAV 454
>sp|Q99767|APBA2_HUMAN Amyloid-beta A4 precursor protein-binding
family A member 2 OS=Homo sapiens OX=9606 GN=APBA2 PE=1 SV=3
Length=749
Score = 55.4 bits (132), Expect = 1e-06, Method: Composition-based stats.
Identities = 25/106 (24%), Positives = 49/106 (46%), Gaps = 6/106 (6%)
Query 246 IGQYGGETVKIVRIEK-ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEI 304
+ V V I++ LG +V+N II +++GG AE+ G + G ++EI
Sbjct 649 LNIVSCPPVTTVLIKRPDLKYQLGFSVQNG----IICSLMRGGIAER-GGVRVGHRIIEI 703
Query 305 NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHV 350
NG + ++ LS+ G + +P+ + +ET +++
Sbjct 704 NGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI 749
Score = 54.3 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 40/220 (18%), Positives = 86/220 (39%), Gaps = 13/220 (6%)
Query 126 DLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISN 185
DLF S + I+ D+Q L + D N + + + +
Sbjct 430 DLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSASQDCIETTPG 489
Query 186 AQDLAQEVQTVLKPVHHKEGQELTALLNTPH---IQALLLAH----DKVAEQEM-QLEPI 237
AQ+ ++ + + ++ Q + + Q L A+ + ++++E +
Sbjct 490 AQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDIINT 549
Query 238 TDERVYESIGQYGGETVKIVRIEKARDIPLGATV-----RNEMDSVIISRIVKGGAAEKS 292
+ + I E K +++EK + LG V + + +VI++ ++ GG A +S
Sbjct 550 QEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARS 609
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
G L GD+++ ING + G + ++ + L
Sbjct 610 GKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKL 649
>sp|O62674|IL16_CHLAE Pro-interleukin-16 OS=Chlorocebus aethiops
OX=9534 GN=IL16 PE=2 SV=1
Length=631
Score = 55.4 bits (132), Expect = 1e-06, Method: Composition-based stats.
Identities = 23/129 (18%), Positives = 52/129 (40%), Gaps = 16/129 (12%)
Query 200 VHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRI 259
H+ GQ + +LL++ ++ L+ ++ Q V I+
Sbjct 372 SSHQSGQSVISLLSSEELKQLIEE--------------VKVLDEATLKQLDSIHVTILHK 417
Query 260 EKARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
E+ + ++++ + + ++ G A + G + +G+EVL ING ++G N+
Sbjct 418 EEGAGLGFSLAGGADLENKVITVHKVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHNDA 477
Query 318 FDLLSDMHG 326
+L
Sbjct 478 LAILRQARE 486
Score = 53.1 bits (126), Expect = 7e-06, Method: Composition-based stats.
Identities = 50/247 (20%), Positives = 92/247 (37%), Gaps = 19/247 (8%)
Query 110 IVLESPHYAVKILEIEDLFS--SLKHIQHTLVDSQSQED-ISLLLQLVQNKDFQNAFKIH 166
I L S +++E + +LK + V +E+ L L D +N K+
Sbjct 381 ISLLSSEELKQLIEEVKVLDEATLKQLDSIHVTILHKEEGAGLGFSLAGGADLEN--KVI 438
Query 167 NAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDK 226
V N + I ++ LK H + + P QA+++
Sbjct 439 TVHKVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHNDALAILRQAREPR-QAVIVTRKL 497
Query 227 VAEQEMQL------EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---- 276
AE L S+ TV V +EK LG ++
Sbjct 498 TAESMPDLNSTTDSAASASAASDVSVESSAEATVYTVTLEK-MSAGLGFSLEGGKGSLHG 556
Query 277 --SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP 334
+ I+RI KG A+E+S + GDE+L++ G ++G E ++++ + ++I
Sbjct 557 DKPLTINRIFKGAASEQSETIQPGDEILQLAGTAMQGLTRFEAWNIIKALPDGPVTIVIR 616
Query 335 SQQIKPP 341
+ ++P
Sbjct 617 RKSLQPK 623
>sp|O35431|APBA2_RAT Amyloid-beta A4 precursor protein-binding
family A member 2 OS=Rattus norvegicus OX=10116 GN=Apba2 PE=1
SV=1
Length=750
Score = 55.4 bits (132), Expect = 1e-06, Method: Composition-based stats.
Identities = 25/106 (24%), Positives = 49/106 (46%), Gaps = 6/106 (6%)
Query 246 IGQYGGETVKIVRIEK-ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEI 304
+ V V I++ LG +V+N II +++GG AE+ G + G ++EI
Sbjct 650 LNIVSCPPVTTVLIKRPDLKYQLGFSVQNG----IICSLMRGGIAER-GGVRVGHRIIEI 704
Query 305 NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHV 350
NG + ++ LS+ G + +P+ + +ET +++
Sbjct 705 NGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI 750
Score = 54.3 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 40/220 (18%), Positives = 86/220 (39%), Gaps = 13/220 (6%)
Query 126 DLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISN 185
DLF S + I+ D+Q L + D N + + + +
Sbjct 431 DLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSASQDCIETTPG 490
Query 186 AQDLAQEVQTVLKPVHHKEGQELTALLNTPH---IQALLLAH----DKVAEQEM-QLEPI 237
AQ+ ++ + + ++ Q + + Q L A+ + ++++E +
Sbjct 491 AQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDIINT 550
Query 238 TDERVYESIGQYGGETVKIVRIEKARDIPLGATV-----RNEMDSVIISRIVKGGAAEKS 292
+ + I E K +++EK + LG V + + +VI++ ++ GG A +S
Sbjct 551 QEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARS 610
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
G L GD+++ ING + G + ++ + L
Sbjct 611 GKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKL 650
>sp|Q6DFV3|RHG21_MOUSE Rho GTPase-activating protein 21 OS=Mus
musculus OX=10090 GN=Arhgap21 PE=1 SV=2
Length=1945
Score = 55.8 bits (133), Expect = 1e-06, Method: Composition-based stats.
Identities = 20/80 (25%), Positives = 42/80 (53%), Gaps = 1/80 (1%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
MD++ + ++ +GG A ++G L GD ++++NG + GK ++V L+ + TL +
Sbjct 103 EPMDTIFVKQVKEGGPAFEAG-LCTGDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSV 161
Query 333 IPSQQIKPPPAKETVIHVKA 352
+P + A ++K
Sbjct 162 MPKDEDILQVAYSQDAYLKG 181
>sp|O62676|IL16_MACFA Pro-interleukin-16 OS=Macaca fascicularis
OX=9541 GN=IL16 PE=3 SV=1
Length=630
Score = 55.4 bits (132), Expect = 1e-06, Method: Composition-based stats.
Identities = 23/129 (18%), Positives = 52/129 (40%), Gaps = 16/129 (12%)
Query 200 VHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRI 259
H+ GQ + +LL++ ++ L+ ++ Q V I+
Sbjct 371 SSHQSGQSVISLLSSEELKQLIEE--------------VKVLDEATLKQLDSIHVTILHK 416
Query 260 EKARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
E+ + ++++ + + ++ G A + G + +G+EVL ING ++G N+
Sbjct 417 EEGAGLGFSLAGGADLENKVITVHKVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHNDA 476
Query 318 FDLLSDMHG 326
+L
Sbjct 477 LAILRQARE 485
Score = 53.1 bits (126), Expect = 6e-06, Method: Composition-based stats.
Identities = 50/247 (20%), Positives = 91/247 (37%), Gaps = 19/247 (8%)
Query 110 IVLESPHYAVKILEIEDLFS--SLKHIQHTLVDSQSQED-ISLLLQLVQNKDFQNAFKIH 166
I L S +++E + +LK + V +E+ L L D +N K+
Sbjct 380 ISLLSSEELKQLIEEVKVLDEATLKQLDSIHVTILHKEEGAGLGFSLAGGADLEN--KVI 437
Query 167 NAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDK 226
V N + I ++ LK H + + P QA+++
Sbjct 438 TVHKVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHNDALAILRQAREPR-QAVIVTRKL 496
Query 227 VAEQEMQL------EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---- 276
AE L S+ TV V +EK LG ++
Sbjct 497 TAESMPDLNSTTDSAASASAASDVSVESSAEATVYTVTLEK-MSAGLGFSLEGGKGSLHG 555
Query 277 --SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP 334
+ I+RI KG A+E+S + GDE+L++ G ++G E ++++ + +I
Sbjct 556 DKPLTINRIFKGAASEQSETIQPGDEILQLAGTAMQGLTRFEAWNIIKALPDGPVTTVIR 615
Query 335 SQQIKPP 341
+ ++P
Sbjct 616 RKSLQPK 622
>sp|Q5RD33|APBA2_PONAB Amyloid-beta A4 precursor protein-binding
family A member 2 OS=Pongo abelii OX=9601 GN=APBA2 PE=2 SV=1
Length=749
Score = 55.4 bits (132), Expect = 1e-06, Method: Composition-based stats.
Identities = 25/106 (24%), Positives = 49/106 (46%), Gaps = 6/106 (6%)
Query 246 IGQYGGETVKIVRIEK-ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEI 304
+ V V I++ LG +V+N II +++GG AE+ G + G ++EI
Sbjct 649 LNIVSCPPVTTVLIKRPDLKYQLGFSVQNG----IICSLMRGGIAER-GGVRVGHRIIEI 703
Query 305 NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHV 350
NG + ++ LS+ G + +P+ + +ET +++
Sbjct 704 NGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI 749
Score = 53.9 bits (128), Expect = 4e-06, Method: Composition-based stats.
Identities = 40/220 (18%), Positives = 86/220 (39%), Gaps = 13/220 (6%)
Query 126 DLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISN 185
DLF S + I+ D+Q L + D N + + + +
Sbjct 430 DLFISAQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSASQDCIETTPG 489
Query 186 AQDLAQEVQTVLKPVHHKEGQELTALLNTPH---IQALLLAH----DKVAEQEM-QLEPI 237
AQ+ ++ + + ++ Q + + Q L A+ + ++++E +
Sbjct 490 AQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDIINT 549
Query 238 TDERVYESIGQYGGETVKIVRIEKARDIPLGATV-----RNEMDSVIISRIVKGGAAEKS 292
+ + I E K +++EK + LG V + + +VI++ ++ GG A +S
Sbjct 550 QEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARS 609
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
G L GD+++ ING + G + ++ + L
Sbjct 610 GKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKL 649
>sp|O62675|IL16_MACMU Pro-interleukin-16 OS=Macaca mulatta OX=9544
GN=IL16 PE=2 SV=1
Length=630
Score = 55.4 bits (132), Expect = 1e-06, Method: Composition-based stats.
Identities = 23/129 (18%), Positives = 52/129 (40%), Gaps = 16/129 (12%)
Query 200 VHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRI 259
H+ GQ + +LL++ ++ L+ ++ Q V I+
Sbjct 371 SSHQSGQSVISLLSSEELKQLIEE--------------VKVLDEATLKQLDSIHVTILHK 416
Query 260 EKARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
E+ + ++++ + + ++ G A + G + +G+EVL ING ++G N+
Sbjct 417 EEGAGLGFSLAGGADLENKVITVHKVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHNDA 476
Query 318 FDLLSDMHG 326
+L
Sbjct 477 LAILRQARE 485
Score = 53.1 bits (126), Expect = 7e-06, Method: Composition-based stats.
Identities = 50/247 (20%), Positives = 92/247 (37%), Gaps = 19/247 (8%)
Query 110 IVLESPHYAVKILEIEDLFS--SLKHIQHTLVDSQSQED-ISLLLQLVQNKDFQNAFKIH 166
I L S +++E + +LK + V +E+ L L D +N K+
Sbjct 380 ISLLSSEELKQLIEEVKVLDEATLKQLDSIHVTILHKEEGAGLGFSLAGGADLEN--KVI 437
Query 167 NAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDK 226
V N + I ++ LK H + + P QA+++
Sbjct 438 TVHKVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHNDALAILRQAREPR-QAVIVTRKL 496
Query 227 VAEQEMQL------EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---- 276
AE L S+ TV V +EK LG ++
Sbjct 497 TAESMPDLNSTTDSAASASAASDVSVESSAEATVYTVTLEK-MSAGLGFSLEGGKGSLHG 555
Query 277 --SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP 334
+ I+RI KG A+E+S + GDE+L++ G ++G E ++++ + ++I
Sbjct 556 DKPLTINRIFKGAASEQSETIQPGDEILQLAGTAMQGLTRFEAWNIIKALPDGPVTIVIR 615
Query 335 SQQIKPP 341
+ ++P
Sbjct 616 RKSLQPK 622
>sp|Q13588|GRAP_HUMAN GRB2-related adapter protein OS=Homo sapiens
OX=9606 GN=GRAP PE=1 SV=1
Length=217
Score = 53.1 bits (126), Expect = 1e-06, Method: Composition-based stats.
Identities = 31/157 (20%), Positives = 58/157 (37%), Gaps = 18/157 (11%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEV------LEINGIEI----RG 311
+R + ++ + R + E S ++ GD+V E +G +
Sbjct 66 SRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEEKF 125
Query 312 KDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGL 371
+NE+ D + + +P +A FD+ D L
Sbjct 126 NSLNELVDFYRTTTIAKKRQIFLRDE-EPLLKSPGACFAQAQFDFSAQDPSQ-------L 177
Query 372 SFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
SF++GDI+ V+ + DP+WW+ G P + + P
Sbjct 178 SFRRGDIIEVLERPDPHWWRGRSCGRVGFFPRSYVQP 214
>sp|Q8CSK8|CTPAL_STAES Probable CtpA-like serine protease OS=Staphylococcus
epidermidis (strain ATCC 12228 / FDA PCI 1200)
OX=176280 GN=SE_1113 PE=3 SV=1
Length=491
Score = 55.1 bits (131), Expect = 1e-06, Method: Composition-based stats.
Identities = 32/163 (20%), Positives = 72/163 (44%), Gaps = 6/163 (4%)
Query 198 KPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIV 257
+ + K+ + + LN + + + DK+ + + + + + S ET +
Sbjct 67 QRANLKKIEYVYQTLNKDYYKK--QSSDKLTQSAIDGM-VKELKDPYSEYMTAEETKQFN 123
Query 258 RIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
+ +GA ++ + + + ++ +K AEK+G + D V ++N + GK +++V
Sbjct 124 EGVSGDFVGIGAEMQKKNEQISVTSPMKDSPAEKAG-IQPKDIVTQVNHHSVVGKPLDQV 182
Query 318 FDLLSDMHGT-LTFVLIPSQQIKPPPAKETVIHVKAHFDYDPS 359
++ GT +T + Q K K IHVK+ +Y+
Sbjct 183 VKMVRGKKGTYVTLTIKRGSQEKDIKIKRDTIHVKSV-EYEKK 224
>sp|Q5HPB7|CTPAL_STAEQ Probable CtpA-like serine protease OS=Staphylococcus
epidermidis (strain ATCC 35984 / RP62A) OX=176279
GN=SERP0996 PE=3 SV=1
Length=491
Score = 55.1 bits (131), Expect = 1e-06, Method: Composition-based stats.
Identities = 32/163 (20%), Positives = 72/163 (44%), Gaps = 6/163 (4%)
Query 198 KPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIV 257
+ + K+ + + LN + + + DK+ + + + + + S ET +
Sbjct 67 QRANLKKIEYVYQTLNKDYYKK--QSSDKLTQSAIDGM-VKELKDPYSEYMTAEETKQFN 123
Query 258 RIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
+ +GA ++ + + + ++ +K AEK+G + D V ++N + GK +++V
Sbjct 124 EGVSGDFVGIGAEMQKKNEQISVTSPMKDSPAEKAG-IQPKDIVTQVNHHSVVGKPLDQV 182
Query 318 FDLLSDMHGT-LTFVLIPSQQIKPPPAKETVIHVKAHFDYDPS 359
++ GT +T + Q K K IHVK+ +Y+
Sbjct 183 VKMVRGKKGTYVTLTIKRGSQEKDIKIKRDTIHVKSV-EYEKK 224
>sp|A7UA95|RADIL_DANRE Ras-associating and dilute domain-containing
protein OS=Danio rerio OX=7955 GN=radil PE=2 SV=1
Length=1124
Score = 55.4 bits (132), Expect = 1e-06, Method: Composition-based stats.
Identities = 22/89 (25%), Positives = 37/89 (42%), Gaps = 5/89 (6%)
Query 253 TVKIVRIEKA-RDIPLGATVRN----EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
+V +V ++K + +G + I ++ G A G L GD +L +NG
Sbjct 1024 SVFVVDLDKGPYGLGMGLIDGLHTPLNSPGIYIRTLIPDGPAAADGRLCIGDRILAVNGT 1083
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPSQ 336
+ G D DL+ G L F++ S
Sbjct 1084 SLIGADYQSAVDLIRLGGGRLRFLVAKSD 1112
>sp|Q69Z89|RADIL_MOUSE Ras-associating and dilute domain-containing
protein OS=Mus musculus OX=10090 GN=Radil PE=1 SV=2
Length=1099
Score = 55.4 bits (132), Expect = 1e-06, Method: Composition-based stats.
Identities = 20/86 (23%), Positives = 36/86 (42%), Gaps = 5/86 (6%)
Query 256 IVRIEKA-RDIPLGATVRNEMD----SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
+V +E+ + +G + I ++ G A G L GD++LE+NG +R
Sbjct 1000 MVELERGPSGLGMGLIDGMHTPLGAQGLYIQTLLPGSPAASDGRLSLGDQILEVNGSSLR 1059
Query 311 GKDVNEVFDLLSDMHGTLTFVLIPSQ 336
G DL+ + F++ S
Sbjct 1060 GVSYMRAVDLIRHGGKKMRFLVAKSD 1085
>sp|O08774|RGS12_RAT Regulator of G-protein signaling 12 OS=Rattus
norvegicus OX=10116 GN=Rgs12 PE=1 SV=1
Length=1387
Score = 55.4 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 22/97 (23%), Positives = 42/97 (43%), Gaps = 3/97 (3%)
Query 250 GGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
V+ V + + R G T+ + ++S +++G A+ G L GD++L IN I +
Sbjct 15 APPRVRSVEVARGRA-GYGFTLSGQ-APCVLSCVMRGSPADFVG-LRAGDQILAINEINV 71
Query 310 RGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKET 346
+ +V L+ G L V+ P + +
Sbjct 72 KKASHEDVVKLIGKCSGVLRMVISEGSSHVEPSSSDE 108
>sp|Q7A5M9|CTPAL_STAAN Probable CtpA-like serine protease OS=Staphylococcus
aureus (strain N315) OX=158879 GN=SA1253 PE=1
SV=1
Length=496
Score = 54.7 bits (130), Expect = 2e-06, Method: Composition-based stats.
Identities = 26/99 (26%), Positives = 50/99 (51%), Gaps = 3/99 (3%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ +GA ++ + D ++++ +KG AE++G + D + ++NG I+GK ++EV +
Sbjct 133 GDFVGIGAEMQKKNDQIMVTSPMKGSPAERAG-IRPKDVITKVNGKSIKGKALDEVVKDV 191
Query 322 SDMHGT-LTFVLIPSQQIKPPPAKETVIHVKAHFDYDPS 359
T +T + + K K IHVK+ DY
Sbjct 192 RGKENTEVTLTVQRGSEEKDVKIKREKIHVKSV-DYKKK 229
>sp|Q99U67|CTPAL_STAAM Probable CtpA-like serine protease OS=Staphylococcus
aureus (strain Mu50 / ATCC 700699) OX=158878 GN=SAV1420
PE=3 SV=1
Length=496
Score = 54.7 bits (130), Expect = 2e-06, Method: Composition-based stats.
Identities = 26/99 (26%), Positives = 50/99 (51%), Gaps = 3/99 (3%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ +GA ++ + D ++++ +KG AE++G + D + ++NG I+GK ++EV +
Sbjct 133 GDFVGIGAEMQKKNDQIMVTSPMKGSPAERAG-IRPKDVITKVNGKSIKGKALDEVVKDV 191
Query 322 SDMHGT-LTFVLIPSQQIKPPPAKETVIHVKAHFDYDPS 359
T +T + + K K IHVK+ DY
Sbjct 192 RGKENTEVTLTVQRGSEEKDVKIKREKIHVKSV-DYKKK 229
>sp|A8MUH7|PDZ1P_HUMAN Putative PDZ domain-containing protein
PDZK1P1 OS=Homo sapiens OX=9606 GN=PDZK1P1 PE=5 SV=2
Length=402
Score = 54.3 bits (129), Expect = 2e-06, Method: Composition-based stats.
Identities = 18/106 (17%), Positives = 42/106 (40%), Gaps = 6/106 (6%)
Query 227 VAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKG 286
+++ D + + ++ + E L A + I + KG
Sbjct 238 PTPTSLEVSSPPD---TTEEEDHKPKLCRLAKGENGYGFHLNAIRG--LPGSFIKEVQKG 292
Query 287 GAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
G A+ +G L + D ++E+NG+ + + +V D + +T ++
Sbjct 293 GPADLAG-LEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLV 337
Score = 47.7 bits (112), Expect = 2e-04, Method: Composition-based stats.
Identities = 20/118 (17%), Positives = 46/118 (39%), Gaps = 7/118 (6%)
Query 259 IEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVF 318
+++ V ++ I G A ++G+L + D ++E+NG + EV
Sbjct 17 VKEGGSHGFSLKTVQGKKGVYMTDITPQGVAMRAGVLAD-DHLIEVNGENVEDASHEEVV 75
Query 319 DLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKG 376
+ + + F+L+ + K + K F + + +P + + +KG
Sbjct 76 EKVKKSGSRVMFLLVDKETDKRHVEQ------KIQFKRETASLKLLPHQPRIVEMKKG 127
>sp|Q22366|RIM_CAEEL Rab-3-interacting molecule unc-10 OS=Caenorhabditis
elegans OX=6239 GN=unc-10 PE=2 SV=2
Length=1563
Score = 55.1 bits (131), Expect = 2e-06, Method: Composition-based stats.
Identities = 21/88 (24%), Positives = 36/88 (41%), Gaps = 4/88 (5%)
Query 262 ARDIPLGATVRNEMD----SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
D+ L D I+++ G A+ G L GDEV+E NG ++ +V
Sbjct 655 NGDLGLKIVGGRRTDTGKLGAFITQVKPGSVADTIGRLRPGDEVVEWNGQSLQNATYEQV 714
Query 318 FDLLSDMHGTLTFVLIPSQQIKPPPAKE 345
+D ++ + LI S+ P +
Sbjct 715 YDSIAASRYDTSVELIVSRSAIIPGGDD 742
>sp|Q9JIL4|NHRF3_MOUSE Na(+)/H(+) exchange regulatory cofactor
NHE-RF3 OS=Mus musculus OX=10090 GN=Pdzk1 PE=1 SV=1
Length=519
Score = 54.7 bits (130), Expect = 2e-06, Method: Composition-based stats.
Identities = 21/106 (20%), Positives = 49/106 (46%), Gaps = 1/106 (1%)
Query 260 EKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFD 319
++ ++ + + D +I I +G AEK+GLL +GD VL ING+ + ++ +V +
Sbjct 15 QEGQNYGFFLRIEKDTDGHLIRVIEEGSPAEKAGLL-DGDRVLRINGVFVDKEEHAQVVE 73
Query 320 LLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVP 365
L+ ++T +++ + + + + + + P
Sbjct 74 LVRKSGNSVTLLVLDGDSYEKAVKNQVDLKELDQSQREAALNDKKP 119
Score = 54.3 bits (129), Expect = 2e-06, Method: Composition-based stats.
Identities = 24/143 (17%), Positives = 53/143 (37%), Gaps = 2/143 (1%)
Query 191 QEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYG 250
+ ++ + L + Q+ L + V E + + E
Sbjct 313 DQTTLLVLDKEAESIYSLARFSPLLYCQSQELPNGSVKEGPAPIPAPLEATGSEPTEDAE 372
Query 251 GETVKIVRIEKARD-IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
G K+ R+ K D + + +GG A+K+GL +E D ++E+NG +
Sbjct 373 GHKPKLCRLLKEDDSYGFHLNAIRGQPGSFVKEVQQGGPADKAGLENE-DVIIEVNGENV 431
Query 310 RGKDVNEVFDLLSDMHGTLTFVL 332
+ + + V + + +T ++
Sbjct 432 QEEPYDRVVERIKSSGKHVTLLV 454
Score = 51.2 bits (121), Expect = 3e-05, Method: Composition-based stats.
Identities = 25/119 (21%), Positives = 43/119 (36%), Gaps = 16/119 (13%)
Query 255 KIVRIEKAR-DIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
++V I+K E II I G AE +G L D V+ +NG + D
Sbjct 242 RVVVIKKGSNGYGFYLRAGPEQKGQIIKDIEPGSPAEAAG-LKNNDLVVAVNGKSVEALD 300
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLS 372
+ V +++ T +++ + I+ A F P + C+ L
Sbjct 301 HDGVVEMIRKGGDQTTLLVLDKE--------AESIYSLARF------SPLLYCQSQELP 345
Score = 47.0 bits (110), Expect = 5e-04, Method: Composition-based stats.
Identities = 20/118 (17%), Positives = 46/118 (39%), Gaps = 7/118 (6%)
Query 259 IEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVF 318
+++ V ++ I+ G A K+G+L + D ++E+NG + EV
Sbjct 139 VKEGNSFGFSLKTIQGKKGVYLTDIMPQGVAMKAGVLAD-DHLIEVNGENVENASHEEVV 197
Query 319 DLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKG 376
+ ++ + F+L+ + K F + + +P + + +KG
Sbjct 198 EKVTKSGSRIMFLLV---DKETARCHSEQ---KTQFKRETASLKLLPHQPRVVVIKKG 249
>sp|O17583|LIN10_CAEEL Protein lin-10 OS=Caenorhabditis elegans
OX=6239 GN=lin-10 PE=1 SV=1
Length=982
Score = 55.1 bits (131), Expect = 2e-06, Method: Composition-based stats.
Identities = 23/100 (23%), Positives = 47/100 (47%), Gaps = 6/100 (6%)
Query 252 ETVKIVRIEK-ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
V VRI + LG +V+N + I +++GG AE+ G + G ++EING +
Sbjct 888 PPVVEVRIRRPDTKYQLGFSVQNGV----ICSLLRGGIAER-GGIRVGHRIIEINGTSVV 942
Query 311 GKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHV 350
+ + ++L+ G + +P+ + +E ++
Sbjct 943 AVAHDRIVNMLATAVGEIHMKTMPTSMFRLLTGQEQPQYI 982
Score = 52.0 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 52/295 (18%), Positives = 101/295 (34%), Gaps = 34/295 (12%)
Query 45 TRMMPIRRSAQLERIRQQQEDMRRRREEEGKKQELDLNSSMRLK-KLAQIPPKTGIDNPM 103
T+M+ R ++ R+ Q QE + R + EG Q ++ + L +I +
Sbjct 615 TQMLCESRGSKAARMAQAQEAVARVKAPEGDVQP---STEIDLFISTEKIMVLNTDLQRI 671
Query 104 FDTEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAF 163
DT+ + H I I D+ + + + S S E S
Sbjct 672 SDTDVRQDILMDHALRTISYIADIGDLVVLMARRMSTSHSDESCS------DGDSSGGGV 725
Query 164 KIHNAITVHMNKASPPFPLISN-AQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLL 222
+ + H+ ++ + + Q L+ + L + Q +L
Sbjct 726 RKTPKVICHVFESDEASFIAQSIGQAFQVAYVEFLRANGIDDPSYLRQI----DYQEVLN 781
Query 223 AHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATV-----RNEMDS 277
+ + E ET K V + K PLG V + + +
Sbjct 782 SQ--------------ELLGDELEMFAKKETQKEVVVPKKAGEPLGIVVVESGWGSMLPT 827
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
V+++ + G A S L+ GD+++ INGI + G ++ + +M +
Sbjct 828 VVLAHMNPVGPAAHSNKLNIGDQIININGISLVGLPLSAAQTQIKNMKTATAVRM 882
>sp|Q5T5U3|RHG21_HUMAN Rho GTPase-activating protein 21 OS=Homo
sapiens OX=9606 GN=ARHGAP21 PE=1 SV=2
Length=1958
Score = 55.1 bits (131), Expect = 2e-06, Method: Composition-based stats.
Identities = 19/75 (25%), Positives = 40/75 (53%), Gaps = 1/75 (1%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
MD++ + ++ +GG A ++G L GD ++++NG + GK ++V L+ + TL +
Sbjct 97 EPMDTIFVKQVKEGGPAFEAG-LCTGDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSV 155
Query 333 IPSQQIKPPPAKETV 347
+P + + T
Sbjct 156 MPKDEDILQVLQFTK 170
>sp|Q2YXZ9|CTPAL_STAAB Probable CtpA-like serine protease OS=Staphylococcus
aureus (strain bovine RF122 / ET3-1) OX=273036
GN=SAB1275c PE=3 SV=1
Length=496
Score = 54.3 bits (129), Expect = 2e-06, Method: Composition-based stats.
Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ +GA ++ + D ++++ +KG AE++G + D + ++NG I+GK ++EV +
Sbjct 133 GDFVGIGAEMQKKNDQIMVTSPMKGSPAERAG-IRPKDVITKVNGKSIKGKALDEVVKDV 191
Query 322 SDMHGT-LTFVLIPSQQIKPPPAKETVIHVKA 352
T +T + + K K IHVK+
Sbjct 192 RGKENTEVTLTVQRGSEEKDVKIKREKIHVKS 223
>sp|P42690|SRK4_SPOLA Tyrosine-protein kinase isoform SRK4 OS=Spongilla
lacustris OX=6055 GN=SRK1 PE=2 SV=1
Length=506
Score = 54.3 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 17/63 (27%), Positives = 31/63 (49%), Gaps = 10/63 (16%)
Query 354 FDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
+DYD D LSF+KGD++++IS ++ +WW A + + G +P
Sbjct 63 YDYDSRTDDD-------LSFKKGDLMYIISTDEGDWWFARSKDTAGKE---GYIPSNYVA 112
Query 414 QQR 416
+ +
Sbjct 113 EYK 115
>sp|Q6GGY8|CTPAL_STAAR Probable CtpA-like serine protease OS=Staphylococcus
aureus (strain MRSA252) OX=282458 GN=SAR1432 PE=3
SV=1
Length=496
Score = 54.3 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ +GA ++ + D ++++ +KG AE++G + D + ++NG I+GK ++EV +
Sbjct 133 GDFVGIGAEMQKKNDQIMVTSPMKGSPAERAG-IRPKDVITKVNGKSIKGKALDEVVKDV 191
Query 322 SDMHGT-LTFVLIPSQQIKPPPAKETVIHVKA 352
T +T + + K K IHVK+
Sbjct 192 RGKENTEVTLTVQRGSEEKDVKIKREKIHVKS 223
>sp|O62666|IL16_PANTR Pro-interleukin-16 OS=Pan troglodytes OX=9598
GN=IL16 PE=2 SV=1
Length=631
Score = 54.3 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 25/139 (18%), Positives = 60/139 (43%), Gaps = 7/139 (5%)
Query 190 AQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQY 249
+E L + + ++L + + +LL + + ++ ++ + DE ++ Q
Sbjct 353 LREYTEGLTEAKEDDDGDHSSLQSGQSVISLLSSEEL--KKLIEEVKVLDEA---TLKQL 407
Query 250 GGETVKIVRIEKARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
V I+ E+ + ++++ + + R+ G A + G + +G+EVL ING
Sbjct 408 DSIHVTILHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGK 467
Query 308 EIRGKDVNEVFDLLSDMHG 326
++G N+ +L
Sbjct 468 SLKGTTHNDALAILRQARE 486
Score = 51.2 bits (121), Expect = 2e-05, Method: Composition-based stats.
Identities = 54/255 (21%), Positives = 91/255 (36%), Gaps = 21/255 (8%)
Query 110 IVLESPHYAVKILEIEDLFS--SLKHIQHTLVDSQSQED-ISLLLQLVQNKDFQNAFKIH 166
I L S K++E + +LK + V +E+ L L D +N K+
Sbjct 381 ISLLSSEELKKLIEEVKVLDEATLKQLDSIHVTILHKEEGAGLGFSLAGGADLEN--KVI 438
Query 167 NAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDK 226
V N + I ++ LK H + + P QA+++
Sbjct 439 TVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHNDALAILRQAREPR-QAVIVTRKL 497
Query 227 VAEQEMQL------EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---- 276
E L S+ TV V +EK LG ++
Sbjct 498 TPEAMPDLNSSTDSAASASAASDVSVESTAEATVCTVTLEK-MSAGLGFSLEGGKGSLHG 556
Query 277 --SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD-MHGTLTFVLI 333
+ I+RI KG A+E+S + GDE+L++ G ++G E ++++ G +T V+
Sbjct 557 DKPLTINRIFKGAASEQSETVQPGDEILQLAGTAMQGLTRFEAWNIIKALPDGPVTIVIR 616
Query 334 PSQ-QIKPPPAKETV 347
Q K A
Sbjct 617 RKSLQSKETTAAGDS 631
>sp|Q7Z6J2|GRASP_HUMAN Protein TAMALIN OS=Homo sapiens OX=9606
GN=TAMALIN PE=1 SV=1
Length=395
Score = 53.9 bits (128), Expect = 3e-06, Method: Composition-based stats.
Identities = 21/125 (17%), Positives = 51/125 (41%), Gaps = 12/125 (10%)
Query 244 ESIGQYGGETVKIVRIEKARDIPLGATVR------NEMDSV----IISRIVKGGAAEKSG 293
+++ Q + K++ +EK + G ++ E V + R+ + A+ +G
Sbjct 89 KNLSQSPEQQRKVLTLEKEDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAG 148
Query 294 LLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVK-A 352
L GD + +NG+ + G E+ D++ L + I+ + + ++K
Sbjct 149 -LTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLRLETLYGTSIRKAELEARLQYLKQT 207
Query 353 HFDYD 357
++
Sbjct 208 LYEKW 212
>sp|Q8NWR2|CTPAL_STAAW Probable CtpA-like serine protease OS=Staphylococcus
aureus (strain MW2) OX=196620 GN=MW1310 PE=3 SV=1
Length=496
Score = 54.3 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ +GA ++ + D ++++ +KG AE++G + D + ++NG I+GK ++EV +
Sbjct 133 GDFVGIGAEMQKKNDQIMVTSPMKGSPAERAG-IRPKDVITKVNGKSIKGKALDEVVKDV 191
Query 322 SDMHGT-LTFVLIPSQQIKPPPAKETVIHVKA 352
T +T + + K K IHVK+
Sbjct 192 RGKENTEVTLTVQRGSEEKDVKIKREKIHVKS 223
>sp|Q6G9E1|CTPAL_STAAS Probable CtpA-like serine protease OS=Staphylococcus
aureus (strain MSSA476) OX=282459 GN=SAS1363 PE=3
SV=1
Length=496
Score = 54.3 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ +GA ++ + D ++++ +KG AE++G + D + ++NG I+GK ++EV +
Sbjct 133 GDFVGIGAEMQKKNDQIMVTSPMKGSPAERAG-IRPKDVITKVNGKSIKGKALDEVVKDV 191
Query 322 SDMHGT-LTFVLIPSQQIKPPPAKETVIHVKA 352
T +T + + K K IHVK+
Sbjct 192 RGKENTEVTLTVQRGSEEKDVKIKREKIHVKS 223
>sp|Q5HG01|CTPAL_STAAC Probable CtpA-like serine protease OS=Staphylococcus
aureus (strain COL) OX=93062 GN=SACOL1455 PE=3
SV=1
Length=496
Score = 54.3 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 24/92 (26%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ +GA ++ + D ++++ +KG AE++G + D + ++NG I+GK ++EV +
Sbjct 133 GDFVGIGAEMQKKNDQIMVTSPMKGSPAERAG-IRPKDVITKVNGKSIKGKALDEVVKDV 191
Query 322 SDMHGT-LTFVLIPSQQIKPPPAKETVIHVKA 352
T +T + + K K IHVK+
Sbjct 192 RGKENTEVTLTVQRGSEEKDVKIKREKIHVKS 223
>sp|Q09284|YQJ3_CAEEL PDZ domain-containing protein C52A11.3 OS=Caenorhabditis
elegans OX=6239 GN=C52A11.3 PE=4 SV=2
Length=131
Score = 50.4 bits (119), Expect = 3e-06, Method: Composition-based stats.
Identities = 21/117 (18%), Positives = 41/117 (35%), Gaps = 17/117 (15%)
Query 235 EPITDERVYESIGQY-------------GGETVKIVRIEKARDIPLGATVRNEMDSVIIS 281
P + S +Y G +V+++K + +G V ++I+
Sbjct 17 PPSPPSTITLSSYEYSSLAVGIISDLKEEGCDTLLVKLQKDANRKIGMGVGVRDRGILIT 76
Query 282 RIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
+V G A + L GD +L +NG I + V + L + ++
Sbjct 77 TVVPGSVAAE--KLKVGDRILAVNGRPILDQR--SVVKSVKASGQRLYLQIARPHKV 129
>sp|Q62083|PICK1_MOUSE PRKCA-binding protein OS=Mus musculus OX=10090
GN=Pick1 PE=1 SV=2
Length=416
Score = 53.9 bits (128), Expect = 3e-06, Method: Composition-based stats.
Identities = 19/97 (20%), Positives = 41/97 (42%), Gaps = 6/97 (6%)
Query 257 VRIEKARDIPLGATVRNEMDSV---IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
V ++K +G ++ I ++ A G + GDE+ +NG I+GK
Sbjct 23 VTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGKSIKGKT 82
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHV 350
EV ++ ++ G +T +++ P + + +
Sbjct 83 KVEVAKMIQEVKGEVTIHY---NKLQADPKQGMSLDI 116
>sp|P42686|SRK1_SPOLA Tyrosine-protein kinase isoform SRK1 OS=Spongilla
lacustris OX=6055 GN=SRK1 PE=2 SV=1
Length=505
Score = 53.9 bits (128), Expect = 3e-06, Method: Composition-based stats.
Identities = 17/63 (27%), Positives = 31/63 (49%), Gaps = 10/63 (16%)
Query 354 FDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
+DYD D LSF+KGD++++IS ++ +WW A + + G +P
Sbjct 63 YDYDSRTDDD-------LSFKKGDLMYIISTDEGDWWFARSKDTAGKE---GYIPSNYVA 112
Query 414 QQR 416
+ +
Sbjct 113 EYK 115
>sp|O35274|NEB2_RAT Neurabin-2 OS=Rattus norvegicus OX=10116 GN=Ppp1r9b
PE=1 SV=1
Length=817
Score = 54.3 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 23/121 (19%), Positives = 52/121 (43%), Gaps = 11/121 (9%)
Query 230 QEMQLEPITDERVYESIGQYGGETVKIVRIEKARD--------IPLGATVRNEMDSVIIS 281
+ ++P+ YE + + V +EK + + GA + E + +
Sbjct 470 RNEDVDPMAASAEYELEKRVERLELFPVELEKDSEGLGISIIGMGAGADMGLEKLGIFVK 529
Query 282 RIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL---IPSQQI 338
+ +GGAA + G + D ++E++G + G + +L + G + F++ P +Q
Sbjct 530 TVTEGGAAHRDGRIQVNDLLVEVDGTSLVGVTQSFAASVLRNTKGRVRFMIGRERPGEQS 589
Query 339 K 339
+
Sbjct 590 E 590
>sp|Q6R891|NEB2_MOUSE Neurabin-2 OS=Mus musculus OX=10090 GN=Ppp1r9b
PE=1 SV=1
Length=817
Score = 54.3 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 23/121 (19%), Positives = 52/121 (43%), Gaps = 11/121 (9%)
Query 230 QEMQLEPITDERVYESIGQYGGETVKIVRIEKARD--------IPLGATVRNEMDSVIIS 281
+ ++P+ YE + + V +EK + + GA + E + +
Sbjct 470 RNEDVDPMAASAEYELEKRVERLELFPVELEKDSEGLGISIIGMGAGADMGLEKLGIFVK 529
Query 282 RIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL---IPSQQI 338
+ +GGAA + G + D ++E++G + G + +L + G + F++ P +Q
Sbjct 530 TVTEGGAAHRDGRIQVNDLLVEVDGTSLVGVTQSFAASVLRNTKGRVRFMIGRERPGEQS 589
Query 339 K 339
+
Sbjct 590 E 590
>sp|Q5T2W1|NHRF3_HUMAN Na(+)/H(+) exchange regulatory cofactor
NHE-RF3 OS=Homo sapiens OX=9606 GN=PDZK1 PE=1 SV=2
Length=519
Score = 53.9 bits (128), Expect = 3e-06, Method: Composition-based stats.
Identities = 18/106 (17%), Positives = 42/106 (40%), Gaps = 6/106 (6%)
Query 227 VAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKG 286
+++ D + + ++ + E L A + I + KG
Sbjct 355 PTPTSLEVSSPPD---TTEEVDHKPKLCRLAKGENGYGFHLNAIRG--LPGSFIKEVQKG 409
Query 287 GAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
G A+ +G L + D ++E+NG+ + + +V D + +T ++
Sbjct 410 GPADLAG-LEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLV 454
Score = 50.4 bits (119), Expect = 4e-05, Method: Composition-based stats.
Identities = 29/136 (21%), Positives = 58/136 (43%), Gaps = 16/136 (12%)
Query 260 EKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFD 319
++ ++ + + + ++ + K AEK+G L +GD VL ING+ + ++ +V D
Sbjct 15 QEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAG-LQDGDRVLRINGVFVDKEEHMQVVD 73
Query 320 LLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDIL 379
L+ ++T +++ + VK D + +E GLS +IL
Sbjct 74 LVRKSGNSVTLLVLDGDSYEKA--------VKTRVDL---KELGQSQKEQGLS---DNIL 119
Query 380 H-VISQEDPNWWQAYR 394
V++ W Q
Sbjct 120 SPVMNGGVQTWTQPRL 135
Score = 48.9 bits (115), Expect = 1e-04, Method: Composition-based stats.
Identities = 26/139 (19%), Positives = 50/139 (36%), Gaps = 11/139 (8%)
Query 259 IEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVF 318
+++ V ++ I G A ++G+L + D ++E+NG + EV
Sbjct 139 VKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLAD-DHLIEVNGENVEDASHEEVV 197
Query 319 DLLSDMHGTLTFVLIPSQQIKPPPAKETVI-HVKAHFDYDPSDDPYVPCREL--GLSF-- 373
+ + + F+L+ + K ++ A P V ++ G F
Sbjct 198 EKVKKSGSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQPRIVEMKKGSNGYGFYL 257
Query 374 -----QKGDILHVISQEDP 387
QKG I+ I P
Sbjct 258 RAGSEQKGQIIKDIDSGSP 276
>sp|Q96SB3|NEB2_HUMAN Neurabin-2 OS=Homo sapiens OX=9606 GN=PPP1R9B
PE=1 SV=3
Length=817
Score = 54.3 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 23/121 (19%), Positives = 52/121 (43%), Gaps = 11/121 (9%)
Query 230 QEMQLEPITDERVYESIGQYGGETVKIVRIEKARD--------IPLGATVRNEMDSVIIS 281
+ ++P+ YE + + V +EK + + GA + E + +
Sbjct 470 RNEDVDPMAASAEYELEKRVERLELFPVELEKDSEGLGISIIGMGAGADMGLEKLGIFVK 529
Query 282 RIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL---IPSQQI 338
+ +GGAA + G + D ++E++G + G + +L + G + F++ P +Q
Sbjct 530 TVTEGGAAHRDGRIQVNDLLVEVDGTSLVGVTQSFAASVLRNTKGRVRFMIGRERPGEQS 589
Query 339 K 339
+
Sbjct 590 E 590
>sp|A1A5H8|YES_DANRE Tyrosine-protein kinase yes OS=Danio rerio
OX=7955 GN=yes1 PE=1 SV=1
Length=546
Score = 53.9 bits (128), Expect = 3e-06, Method: Composition-based stats.
Identities = 24/132 (18%), Positives = 38/132 (29%), Gaps = 24/132 (18%)
Query 325 HGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ 384
+ +F + P V A +DY+ LSF KGD +I+
Sbjct 74 GASSSFSTVAVNNPFPGVVTGGVTFFVALYDYEARTSDD-------LSFSKGDRFQIINN 126
Query 385 EDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKK 444
+ +WW+A N G +P + W K +K
Sbjct 127 TEGDWWEARSI----NTGQKGYIPSNYVA-------------PADSIQAEEWYFGKMGRK 169
Query 445 RKKVLYNANKND 456
+ L N
Sbjct 170 DAERLLLLPGNQ 181
>sp|B7WN72|SHANK_CAEEL Protein shank OS=Caenorhabditis elegans
OX=6239 GN=shn-1 PE=1 SV=1
Length=1140
Score = 54.3 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 22/79 (28%), Positives = 40/79 (51%), Gaps = 2/79 (3%)
Query 256 IVRIEKARDIPLGATVRNEMDSV-IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
I+R K +PL ++ ++ + G A ++G L GD +LEI+GI++R
Sbjct 449 ILRGAKHVAMPLNFEPTAQVPALQFFEGVDMSGMAVRAG-LRPGDYLLEIDGIDVRRCSH 507
Query 315 NEVFDLLSDMHGTLTFVLI 333
+EV + + T+T +I
Sbjct 508 DEVVEFIQQAGDTITLKVI 526
>sp|Q557J6|DBNL_DICDI Drebrin-like protein OS=Dictyostelium discoideum
OX=44689 GN=abpE-1 PE=2 SV=1
Length=481
Score = 53.5 bits (127), Expect = 4e-06, Method: Composition-based stats.
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 13/72 (18%)
Query 344 KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDP-NWWQAYREGDEDNQP 402
+ + KA +DY+ +D LSF++GDI+ ++ Q DP WWQ
Sbjct 421 QSGYLQAKALYDYNGENDGD-------LSFREGDIITILDQSDPDGWWQG-----SLPTG 468
Query 403 LAGLVPGKSFQQ 414
G P QQ
Sbjct 469 EQGFFPSNFVQQ 480
>sp|Q6IN97|FRP2L_HUMAN Putative protein FRMPD2-like OS=Homo sapiens
OX=9606 GN=FRMPD2B PE=5 SV=1
Length=320
Score = 53.1 bits (126), Expect = 4e-06, Method: Composition-based stats.
Identities = 26/114 (23%), Positives = 38/114 (33%), Gaps = 19/114 (17%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP----- 334
I R+ G AE++G + GD +L +NG G EV LL +T +L
Sbjct 122 IKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGA 181
Query 335 ----SQQIKPPPAKETVIHVKA----------HFDYDPSDDPYVPCRELGLSFQ 374
Q+ + P +A D D P GL +
Sbjct 182 LPEMEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLR 235
>sp|Q9EP80|PICK1_RAT PRKCA-binding protein OS=Rattus norvegicus
OX=10116 GN=Pick1 PE=1 SV=1
Length=416
Score = 53.5 bits (127), Expect = 4e-06, Method: Composition-based stats.
Identities = 19/97 (20%), Positives = 41/97 (42%), Gaps = 6/97 (6%)
Query 257 VRIEKARDIPLGATVRNEMDSV---IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
V ++K +G ++ I ++ A G + GDE+ +NG I+GK
Sbjct 23 VTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKT 82
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHV 350
EV ++ ++ G +T +++ P + + +
Sbjct 83 KVEVAKMIQEVKGEVTIHY---NKLQADPKQGMSLDI 116
>sp|Q5RCF7|NHRF3_PONAB Na(+)/H(+) exchange regulatory cofactor
NHE-RF3 OS=Pongo abelii OX=9601 GN=PDZK1 PE=2 SV=1
Length=519
Score = 53.5 bits (127), Expect = 4e-06, Method: Composition-based stats.
Identities = 18/106 (17%), Positives = 42/106 (40%), Gaps = 6/106 (6%)
Query 227 VAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKG 286
+++ D + + ++ + E L A + I + KG
Sbjct 355 PTPTSLEVSSPPD---TTEEVDHKPKLCRLAKGENGYGFHLNAIRG--LPGSFIKEVQKG 409
Query 287 GAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
G A+ +G L + D ++E+NG+ + + +V D + +T ++
Sbjct 410 GPADLAG-LEDEDVIIEVNGVNVLDEPYEKVVDRIQSSGKNVTLLV 454
Score = 48.1 bits (113), Expect = 2e-04, Method: Composition-based stats.
Identities = 26/139 (19%), Positives = 50/139 (36%), Gaps = 11/139 (8%)
Query 259 IEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVF 318
+++ V ++ I G A K+G+L + D ++E+NG + +V
Sbjct 139 VKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMKAGVLAD-DHLIEVNGENVEDASHEQVV 197
Query 319 DLLSDMHGTLTFVLIPSQQIKPPPAKETVI-HVKAHFDYDPSDDPYVPCREL--GLSF-- 373
+ + + F+L+ + K ++ A P V ++ G F
Sbjct 198 EKVKKSGSRVMFLLVDKETDKHHVEQKIQFKRETASLKLLPHQPRIVEMKKGSNGYGFYL 257
Query 374 -----QKGDILHVISQEDP 387
QKG I+ I P
Sbjct 258 RAGSEQKGQIIKDIDSGSP 276
>sp|Q2T9M1|PICK1_BOVIN PRKCA-binding protein OS=Bos taurus OX=9913
GN=PICK1 PE=2 SV=1
Length=417
Score = 53.5 bits (127), Expect = 4e-06, Method: Composition-based stats.
Identities = 19/97 (20%), Positives = 41/97 (42%), Gaps = 6/97 (6%)
Query 257 VRIEKARDIPLGATVRNEMDSV---IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
V ++K +G ++ I ++ A G + GDE+ +NG I+GK
Sbjct 23 VTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKT 82
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHV 350
EV ++ ++ G +T +++ P + + +
Sbjct 83 KVEVAKMIQEVKGEVTIHY---NKLQADPKQGMSLDI 116
>sp|Q5REH1|PICK1_PONAB PRKCA-binding protein OS=Pongo abelii OX=9601
GN=PICK1 PE=2 SV=1
Length=415
Score = 53.5 bits (127), Expect = 4e-06, Method: Composition-based stats.
Identities = 19/97 (20%), Positives = 41/97 (42%), Gaps = 6/97 (6%)
Query 257 VRIEKARDIPLGATVRNEMDSV---IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
V ++K +G ++ I ++ A G + GDE+ +NG I+GK
Sbjct 23 VTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKT 82
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHV 350
EV ++ ++ G +T +++ P + + +
Sbjct 83 KVEVAKMIQEVKGEVTIHY---NKLQADPKQGMSLDI 116
>sp|Q4R7Q5|PICK1_MACFA PRKCA-binding protein OS=Macaca fascicularis
OX=9541 GN=PICK1 PE=2 SV=1
Length=415
Score = 53.5 bits (127), Expect = 4e-06, Method: Composition-based stats.
Identities = 19/97 (20%), Positives = 41/97 (42%), Gaps = 6/97 (6%)
Query 257 VRIEKARDIPLGATVRNEMDSV---IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
V ++K +G ++ I ++ A G + GDE+ +NG I+GK
Sbjct 23 VTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKT 82
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHV 350
EV ++ ++ G +T +++ P + + +
Sbjct 83 KVEVAKMIQEVKGEVTIHY---NKLQADPKQGMSLDI 116
>sp|Q9NRD5|PICK1_HUMAN PRKCA-binding protein OS=Homo sapiens OX=9606
GN=PICK1 PE=1 SV=2
Length=415
Score = 53.5 bits (127), Expect = 4e-06, Method: Composition-based stats.
Identities = 19/97 (20%), Positives = 41/97 (42%), Gaps = 6/97 (6%)
Query 257 VRIEKARDIPLGATVRNEMDSV---IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
V ++K +G ++ I ++ A G + GDE+ +NG I+GK
Sbjct 23 VTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVNGRSIKGKT 82
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHV 350
EV ++ ++ G +T +++ P + + +
Sbjct 83 KVEVAKMIQEVKGEVTIHY---NKLQADPKQGMSLDI 116
>sp|O75886|STAM2_HUMAN Signal transducing adapter molecule 2 OS=Homo
sapiens OX=9606 GN=STAM2 PE=1 SV=1
Length=525
Score = 53.5 bits (127), Expect = 4e-06, Method: Composition-based stats.
Identities = 24/109 (22%), Positives = 43/109 (39%), Gaps = 21/109 (19%)
Query 310 RGKDVNEVFDLL------SDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPY 363
+ K+ ++ + T T L PS +I+ V+A +D++ +D
Sbjct 163 KNKEDEDIAKAIELSLQEQKQQHTETKSLYPSSEIQLNNKVARK--VRALYDFEAVEDNE 220
Query 364 VPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSF 412
L+F+ G+I+ V+ D NWW+ +N GL P
Sbjct 221 -------LTFKHGEIIIVLDDSDANWWKG------ENHRGIGLFPSNFV 256
>sp|Q8TEU7|RPGF6_HUMAN Rap guanine nucleotide exchange factor
6 OS=Homo sapiens OX=9606 GN=RAPGEF6 PE=1 SV=2
Length=1601
Score = 53.9 bits (128), Expect = 5e-06, Method: Composition-based stats.
Identities = 17/82 (21%), Positives = 35/82 (43%), Gaps = 5/82 (6%)
Query 254 VKIVRIEKARDIPLGAT---VRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
++V + +R+ PL + + + + + G A SG L GD+++E+NG
Sbjct 529 RQVVLQKASRESPLQFSLNGGSEKGFGIFVEGVEPGSKAADSG-LKRGDQIMEVNGQNFE 587
Query 311 GKDVNEVFDLLSDMHG-TLTFV 331
+ ++L + LT
Sbjct 588 NITFMKAVEILRNNTHLALTVK 609
>sp|Q99NE5|RIMS1_MOUSE Regulating synaptic membrane exocytosis
protein 1 OS=Mus musculus OX=10090 GN=Rims1 PE=1 SV=2
Length=1463
Score = 53.9 bits (128), Expect = 5e-06, Method: Composition-based stats.
Identities = 30/123 (24%), Positives = 48/123 (39%), Gaps = 12/123 (10%)
Query 233 QLEPITDERVYESIGQYGGETVKIVRIEKARDIP--------LGATVRNEMD----SVII 280
+ PI+ V + G + V + K +P L D I
Sbjct 411 ETSPISSHPVTWQPSKEGDRLIGRVILNKRTTMPKESGALLGLKVVGGKMTDLGRLGAFI 470
Query 281 SRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
+++ KG A+ G L GDEVLE NG + G EV++++ + +I S+ I
Sbjct 471 TKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNIILESKSEPQVEIIVSRPIGD 530
Query 341 PPA 343
P
Sbjct 531 IPR 533
>sp|Q8CGE9|RGS12_MOUSE Regulator of G-protein signaling 12 OS=Mus
musculus OX=10090 GN=Rgs12 PE=1 SV=2
Length=1381
Score = 53.9 bits (128), Expect = 5e-06, Method: Composition-based stats.
Identities = 21/97 (22%), Positives = 41/97 (42%), Gaps = 3/97 (3%)
Query 250 GGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
V+ V + + R G T+ + ++S +++G A+ G L GD++L IN I +
Sbjct 15 APPRVRSVEVARGRA-GYGFTLSGQ-APCVLSCVMRGSPADFVG-LRAGDQILAINEINV 71
Query 310 RGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKET 346
+ +V L+ G L V+ + +
Sbjct 72 KKASHEDVVKLIGKCSGVLHMVIAEGTSHVESCSSDE 108
>sp|Q86UT5|NHRF4_HUMAN Na(+)/H(+) exchange regulatory cofactor
NHE-RF4 OS=Homo sapiens OX=9606 GN=NHERF4 PE=1 SV=2
Length=571
Score = 53.5 bits (127), Expect = 5e-06, Method: Composition-based stats.
Identities = 27/154 (18%), Positives = 56/154 (36%), Gaps = 17/154 (11%)
Query 191 QEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYG 250
++ V++ + + L +L AHD Q E +
Sbjct 172 EDYAVVVRRIRASSPRVLLTVLAR-------HAHDVARAQ-------LGEDAHLCPTLGP 217
Query 251 GETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
G ++ I K G +V + + GGAAE++G + G +LE+NG+ +
Sbjct 218 GVRPRLCHIVKDEG-GFGFSVTHGNQGPFWLVLSTGGAAERAG-VPPGARLLEVNGVSVE 275
Query 311 GKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAK 344
N++ L +T ++ +++ +
Sbjct 276 KFTHNQLTRKLWQSGQQVTLLVA-GPEVEEQCRQ 308
Score = 52.0 bits (123), Expect = 1e-05, Method: Composition-based stats.
Identities = 18/75 (24%), Positives = 31/75 (41%), Gaps = 1/75 (1%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ + IS++ GG+A ++G L GD +LE+NG + G++ E L
Sbjct 475 GGSYGFRLSCVASGPRLFISQVTPGGSAARAG-LQVGDVILEVNGYPVGGQNDLERLQQL 533
Query 322 SDMHGTLTFVLIPSQ 336
+ L L
Sbjct 534 PEAEPPLCLKLAARS 548
Score = 50.1 bits (118), Expect = 5e-05, Method: Composition-based stats.
Identities = 17/104 (16%), Positives = 38/104 (37%), Gaps = 10/104 (10%)
Query 235 EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD--SVIISRIVKGGAAEKS 292
P + + E + + K G ++ E+ ++ R+ G +A++
Sbjct 101 PPHPPD-------PWSLERPRFCLLSKEEGKSFGFHLQQELGRAGHVVCRVDPGTSAQRQ 153
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQ 336
G L EGD +L +N + +D V + + ++
Sbjct 154 G-LQEGDRILAVNNDVVEHEDYAVVVRRIRASSPRVLLTVLARH 196
Score = 45.4 bits (106), Expect = 0.001, Method: Composition-based stats.
Identities = 24/130 (18%), Positives = 46/130 (35%), Gaps = 9/130 (7%)
Query 209 TALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLG 268
L + LL+A +V EQ QL + G + + +EK G
Sbjct 284 RKLWQSGQQVTLLVAGPEVEEQCRQLG--LPLAAPLAEGWALPTKPRCLHLEKGPQ-GFG 340
Query 269 ATVRNEMD-----SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD 323
+R E + + G A+K+G + GD ++ + G + G E +
Sbjct 341 FLLREEKGLDGRPGQFLWEVDPGLPAKKAG-MQAGDRLVAVAGESVEGLGHEETVSRIQG 399
Query 324 MHGTLTFVLI 333
++ ++
Sbjct 400 QGSCVSLTVV 409
>sp|P70441|NHRF1_MOUSE Na(+)/H(+) exchange regulatory cofactor
NHE-RF1 OS=Mus musculus OX=10090 GN=Nherf1 PE=1 SV=3
Length=355
Score = 52.8 bits (125), Expect = 5e-06, Method: Composition-based stats.
Identities = 21/123 (17%), Positives = 42/123 (34%), Gaps = 2/123 (2%)
Query 244 ESIGQYGGETVKIVRIEKA-RDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVL 302
+ G ++ +EK I + G AEKSGLL GD ++
Sbjct 2 SADAAAGEPLPRLCCLEKGPNGYGFHLHGEKGKVGQFIRLVEPGSPAEKSGLL-AGDRLV 60
Query 303 EINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDP 362
E+NG + + +V + + +++ + + I + + S+
Sbjct 61 EVNGENVEKETHQQVVSRIRAALNAVRLLVVDPETDERLKKLGVSIREELLRPQEKSEQA 120
Query 363 YVP 365
P
Sbjct 121 EPP 123
Score = 49.3 bits (116), Expect = 8e-05, Method: Composition-based stats.
Identities = 21/122 (17%), Positives = 42/122 (34%), Gaps = 9/122 (7%)
Query 226 KVAEQEMQLEPITDERVYESIGQYGGETV-------KIVRIEKA-RDIPLGATVRNEMDS 277
+ E+ Q EP +E+ Q E ++ ++K
Sbjct 112 RPQEKSEQAEPPAAADTHEAGDQNEAEKSHLRELRPRLCTMKKGPNGYGFNLHSDKSKPG 171
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
I + AE SG L D ++E+NG+ + GK +V + +++ +
Sbjct 172 QFIRAVDPDSPAEASG-LRAQDRIVEVNGVCMEGKQHGDVVSAIKGGGDEAKLLVVDKET 230
Query 338 IK 339
+
Sbjct 231 DE 232
>sp|Q6CVA8|HSE1_KLULA Class E vacuolar protein-sorting machinery
protein HSE1 OS=Kluyveromyces lactis (strain ATCC 8585 /
CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) OX=284590
GN=HSE1 PE=3 SV=1
Length=508
Score = 53.1 bits (126), Expect = 5e-06, Method: Composition-based stats.
Identities = 28/114 (25%), Positives = 51/114 (45%), Gaps = 15/114 (13%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
V+A +D++ ++ LSF+KGD++ V+ Q +WW+ G PL + P
Sbjct 227 VRAMYDFNSTEQDE-------LSFKKGDLICVVEQVYRDWWRGTLAGSVGIFPLNYVTPV 279
Query 410 KSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEI 463
QQ A ++ +E +++ K N + + L A D ++EI
Sbjct 280 TEPSQQELAAERAKDE--------QVFAQKDNVDRLQNKLREAGNADITQDQEI 325
>sp|Q92783|STAM1_HUMAN Signal transducing adapter molecule 1 OS=Homo
sapiens OX=9606 GN=STAM PE=1 SV=3
Length=540
Score = 53.1 bits (126), Expect = 6e-06, Method: Composition-based stats.
Identities = 28/127 (22%), Positives = 49/127 (39%), Gaps = 20/127 (16%)
Query 309 IRGKDVNE----VFDL-LSDMHGTLTF--VLIPSQQIKPPPAKETVIHVKAHFDYDPSDD 361
+ K E +L L + T L PS + V+A +D++ ++D
Sbjct 167 VANKKEEEDLAKAIELSLKEQRQQSTTLSTLYPSTSSLLTNHQHEGRKVRAIYDFEAAED 226
Query 362 PYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQ 421
L+F+ G+I+ V+ DPNWW+ + GL P A +
Sbjct 227 NE-------LTFKAGEIITVLDDSDPNWWKG------ETHQGIGLFPSNFVTADLTAEPE 273
Query 422 TIEEDKE 428
I+ +K+
Sbjct 274 MIKTEKK 280
>sp|Q9JIR4|RIMS1_RAT Regulating synaptic membrane exocytosis protein
1 OS=Rattus norvegicus OX=10116 GN=Rims1 PE=1 SV=1
Length=1615
Score = 53.5 bits (127), Expect = 6e-06, Method: Composition-based stats.
Identities = 30/123 (24%), Positives = 48/123 (39%), Gaps = 12/123 (10%)
Query 233 QLEPITDERVYESIGQYGGETVKIVRIEKARDIP--------LGATVRNEMD----SVII 280
+ PI+ V + G + V + K +P L D I
Sbjct 590 ETSPISSHPVTWQPSKEGDRLIGRVILNKRTTMPKESGALLGLKVVGGKMTDLGRLGAFI 649
Query 281 SRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
+++ KG A+ G L GDEVLE NG + G EV++++ + +I S+ I
Sbjct 650 TKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNIILESKSEPQVEIIVSRPIGD 709
Query 341 PPA 343
P
Sbjct 710 IPR 712
>sp|A2ALU4|SHRM2_MOUSE Protein Shroom2 OS=Mus musculus OX=10090
GN=Shroom2 PE=1 SV=1
Length=1481
Score = 53.5 bits (127), Expect = 6e-06, Method: Composition-based stats.
Identities = 28/112 (25%), Positives = 47/112 (42%), Gaps = 7/112 (6%)
Query 252 ETVKIVRIEKARDIPLGAT---VRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIE 308
+ V++V ++ + P G T R + ++I++I +G A L GDE++ IN +
Sbjct 22 DGVRLVEVQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVAINDVS 81
Query 309 IRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
+ G E L+ H TL V+ P H +FD P
Sbjct 82 LSGFR-QEAICLVKGSHKTLKLVVKRKSDPSWRPHSW---HATKYFDVHPEP 129
>sp|O61967|LAP1_CAEEL Protein lap1 OS=Caenorhabditis elegans OX=6239
GN=let-413 PE=1 SV=3
Length=699
Score = 53.1 bits (126), Expect = 7e-06, Method: Composition-based stats.
Identities = 24/126 (19%), Positives = 47/126 (37%), Gaps = 17/126 (13%)
Query 245 SIGQYGGETVKIVRIEKARDIPLGATV-----------RNEMDSVIISRIVKGGAAEKSG 293
S G + + +RI+K LG + N + ++++ G AA + G
Sbjct 557 SNLAAGTQNMHTIRIQKDDTGKLGLSFAGGTSNDPAPNSNGDSGLFVTKVTPGSAAYRCG 616
Query 294 LLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK----PPPAKETVIH 349
L EGD+++ N + + + + + T+ V++ P+ H
Sbjct 617 -LREGDKLIRANDVNMINASQDNAMEAIKK-RETVELVVLRRSPSPVSRTSEPSLNGSSH 674
Query 350 VKAHFD 355
HFD
Sbjct 675 QLNHFD 680
>sp|O45539|SRC2_CAEEL Tyrosine protein-kinase src-2 OS=Caenorhabditis
elegans OX=6239 GN=src-2 PE=1 SV=2
Length=507
Score = 53.1 bits (126), Expect = 7e-06, Method: Composition-based stats.
Identities = 17/65 (26%), Positives = 26/65 (40%), Gaps = 11/65 (17%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A F YD D LSF+K DIL +++ +WW A G +P
Sbjct 64 ALFQYDARTDDD-------LSFKKDDILEILNDTQGDWWFAR----HKATGRTGYIPSNY 112
Query 412 FQQQR 416
+++
Sbjct 113 VAREK 117
>sp|Q86UR5|RIMS1_HUMAN Regulating synaptic membrane exocytosis
protein 1 OS=Homo sapiens OX=9606 GN=RIMS1 PE=1 SV=1
Length=1692
Score = 53.5 bits (127), Expect = 7e-06, Method: Composition-based stats.
Identities = 30/123 (24%), Positives = 48/123 (39%), Gaps = 12/123 (10%)
Query 233 QLEPITDERVYESIGQYGGETVKIVRIEKARDIP--------LGATVRNEMD----SVII 280
+ PI+ V + G + V + K +P L D I
Sbjct 576 ETSPISSHPVTWQPSKEGDRLIGRVILNKRTTMPKDSGALLGLKVVGGKMTDLGRLGAFI 635
Query 281 SRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
+++ KG A+ G L GDEVLE NG + G EV++++ + +I S+ I
Sbjct 636 TKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNIILESKSEPQVEIIVSRPIGD 695
Query 341 PPA 343
P
Sbjct 696 IPR 698
>sp|P34109|MYOD_DICDI Myosin ID heavy chain OS=Dictyostelium discoideum
OX=44689 GN=myoD PE=1 SV=2
Length=1109
Score = 53.1 bits (126), Expect = 8e-06, Method: Composition-based stats.
Identities = 26/105 (25%), Positives = 38/105 (36%), Gaps = 13/105 (12%)
Query 309 IRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRE 368
+ E ++S + Q PA KA +D+D
Sbjct 922 VPNLTPPESLPVVSIPIYKPAMNAKNAPQNSGGPASNVKPSAKALYDFDAE-------SS 974
Query 369 LGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
+ LSF++GDIL V+ Q +WW A +G G VP Q
Sbjct 975 MELSFKEGDILTVLDQSSGDWWDAELKG------RRGKVPSNYLQ 1013
>sp|Q9JJ19|NHRF1_RAT Na(+)/H(+) exchange regulatory cofactor NHE-RF1
OS=Rattus norvegicus OX=10116 GN=Nherf1 PE=1 SV=3
Length=356
Score = 52.4 bits (124), Expect = 8e-06, Method: Composition-based stats.
Identities = 18/91 (20%), Positives = 34/91 (37%), Gaps = 2/91 (2%)
Query 244 ESIGQYGGETVKIVRIEKA-RDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVL 302
+ G ++ +EK I + G AEKSGLL GD ++
Sbjct 2 SADAAAGEPLPRLCCLEKGPNGYGFHLHGEKGKVGQFIRLVEPGSPAEKSGLL-AGDRLV 60
Query 303 EINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
E+NG + + +V + + +++
Sbjct 61 EVNGENVEKETHQQVVSRIRAALNAVRLLVV 91
Score = 50.1 bits (118), Expect = 4e-05, Method: Composition-based stats.
Identities = 24/146 (16%), Positives = 46/146 (32%), Gaps = 13/146 (9%)
Query 203 KEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETV-------- 254
E E L P + LL A +K E P + ++
Sbjct 93 PETDEQLKKLGVPIREELLRAQEKSEHTE---PPAAADTKKAGDQNEAEKSHLERCELRP 149
Query 255 KIVRIEKA-RDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
++ ++K I + AE SG L D ++E+NG+ + GK
Sbjct 150 RLCTMKKGPNGYGFNLHSDKSKPGQFIRAVDPDSPAEASG-LRAQDRIVEVNGVCMEGKQ 208
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIK 339
+V + +++ + +
Sbjct 209 HGDVVSAIKAGGDEAKLLVVDKETDE 234
>sp|P53667|LIMK1_HUMAN LIM domain kinase 1 OS=Homo sapiens OX=9606
GN=LIMK1 PE=1 SV=3
Length=647
Score = 52.8 bits (125), Expect = 8e-06, Method: Composition-based stats.
Identities = 48/261 (18%), Positives = 93/261 (36%), Gaps = 40/261 (15%)
Query 234 LEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNE------------MDSVIIS 281
+ P+ ++ + +S G + TV +V I + G +V + +V +
Sbjct 143 VTPVIEQILPDSPGSHLPHTVTLVSIPASSHGKRGLSVSIDPPHGPPGCGTEHSHTVRVQ 202
Query 282 RIVKGGAA-EKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI--PSQQI 338
+ G + + +H GD +LEING IR ++E+ L+ + L L P +
Sbjct 203 GVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEIDLLIQETSRLLQLTLEHDPHDTL 262
Query 339 KPPPAKETVIHVKAHFDYDPSDDP-YVPCRELGLSFQKGDILHVISQEDPNWWQAYREGD 397
ET P P Y P E G S ++ +L S +
Sbjct 263 GHGLGPETS----------PLSSPAYTPSGEAGSSARQKPVLRSCSID------------ 300
Query 398 EDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDD 457
P AG + + Q++ +++ P + + + K A K
Sbjct 301 --RSPGAGSLGSPASQRKDLGRSESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTH 358
Query 458 YDNEEILTYEEMSLYHQPANR 478
+ E++ +E+ + + R
Sbjct 359 RETGEVMVMKELIRFDEETQR 379
>sp|O14924|RGS12_HUMAN Regulator of G-protein signaling 12 OS=Homo
sapiens OX=9606 GN=RGS12 PE=1 SV=1
Length=1447
Score = 52.8 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 20/82 (24%), Positives = 39/82 (48%), Gaps = 3/82 (4%)
Query 251 GETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
V+ V + + R G T+ + ++S +++G A+ G L GD++L +N I ++
Sbjct 17 PPRVRSVEVARGRA-GYGFTLSGQ-APCVLSCVMRGSPADFVG-LRAGDQILAVNEINVK 73
Query 311 GKDVNEVFDLLSDMHGTLTFVL 332
+V L+ G L V+
Sbjct 74 KASHEDVVKLIGKCSGVLHMVI 95
>sp|Q9Z0G0|GIPC1_MOUSE PDZ domain-containing protein GIPC1 OS=Mus
musculus OX=10090 GN=Gipc1 PE=1 SV=1
Length=333
Score = 51.6 bits (122), Expect = 1e-05, Method: Composition-based stats.
Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 6/100 (6%)
Query 254 VKIVRIEKARDIPLGATVRNEMDS-VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
K V + K+ + LG T+ + I RI +G + L+ GD + ING + G
Sbjct 131 RKEVEVFKS-EEALGLTITDNGAGYAFIKRIKEGSVIDHIQLISVGDMIEAINGQSLLGC 189
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKA 352
EV LL ++ TF L ++ P +I ++
Sbjct 190 RHYEVARLLKELPRGRTFTL----KLTEPRKAFDMISQRS 225
>sp|P13116|SRC2_XENLA Tyrosine-protein kinase Src-2 OS=Xenopus
laevis OX=8355 GN=src-b PE=2 SV=3
Length=532
Score = 52.4 bits (124), Expect = 1e-05, Method: Composition-based stats.
Identities = 19/88 (22%), Positives = 33/88 (38%), Gaps = 11/88 (13%)
Query 326 GTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE 385
G + F + + P V A +DY+ E LSF+KG+ L +++
Sbjct 61 GGVNFSDTITSPQRTGPLAGGVTTFVALYDYESR-------TETDLSFRKGERLQIVNNT 113
Query 386 DPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
+ +WW A + G +P
Sbjct 114 EGDWWLAR----SLSSGQTGYIPSNYVA 137
>sp|Q9QY39|PDZD4_MOUSE PDZ domain-containing protein 4 OS=Mus
musculus OX=10090 GN=Pdzd4 PE=2 SV=2
Length=772
Score = 52.4 bits (124), Expect = 1e-05, Method: Composition-based stats.
Identities = 25/126 (20%), Positives = 51/126 (40%), Gaps = 17/126 (13%)
Query 233 QLEPITDERVYESIGQYGG--ETVKI-------VRIEKA---RDIPLGATVRNEMD---S 277
+L PI+ E + GG E ++ V + K + L R + +
Sbjct 104 ELPPISHEYYDPAEFMEGGPQEAERMDELEYEEVELCKNSHQDKLGLMVCYRTDEEEDLG 163
Query 278 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
+ + + A K G + EGD +++ING++++ + E +LS T +L+ +
Sbjct 164 IYVGEVNPNSIAAKDGRIREGDRIIQINGMDVQNR--EEAVAILSQEENTNISLLVARPE 221
Query 338 IKPPPA 343
+
Sbjct 222 SQLAKR 227
>sp|Q28619|NHRF1_RABIT Na(+)/H(+) exchange regulatory cofactor
NHE-RF1 OS=Oryctolagus cuniculus OX=9986 GN=NHERF1 PE=1 SV=3
Length=358
Score = 51.6 bits (122), Expect = 1e-05, Method: Composition-based stats.
Identities = 21/126 (17%), Positives = 45/126 (36%), Gaps = 5/126 (4%)
Query 244 ESIGQYGGETVKIVRIEKA-RDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVL 302
+ G ++ +EK I + G AEK+GLL GD ++
Sbjct 2 SADAAAGAPLPRLCCLEKGPNGYGFHLHGEKGKVGQYIRLVEPGSPAEKAGLL-AGDRLV 60
Query 303 EINGIEIRGKDVNEVFDLLSDMHGTLTFVLI---PSQQIKPPPAKETVIHVKAHFDYDPS 359
E+NG + + +V + + +++ +Q + + ++A + +
Sbjct 61 EVNGENVEKETHQQVVSRIRAALNAVRLLVVDPDTDEQFRKLGVQIRGELLRAQAGPEQA 120
Query 360 DDPYVP 365
P P
Sbjct 121 GPPAAP 126
Score = 47.4 bits (111), Expect = 3e-04, Method: Composition-based stats.
Identities = 21/129 (16%), Positives = 41/129 (32%), Gaps = 10/129 (8%)
Query 220 LLLAHDKVAEQEMQLEP----ITDERVYESIGQYGGETV----KIVRIEKA-RDIPLGAT 270
LL A + P E + + E ++ ++K
Sbjct 110 LLRAQAGPEQAGPPAAPGEQGPAGENEPREVEKSHPERRELRPRLCAMKKGPNGYGFNLH 169
Query 271 VRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTF 330
I + AE SG L E D ++E+NG+ + GK +V +
Sbjct 170 SDKSRPGQFIRAVDPDSPAEASG-LREQDRIVEVNGVCVEGKQHGDVVTAIKAGGDEAKL 228
Query 331 VLIPSQQIK 339
+++ + +
Sbjct 229 LVVDKETDE 237
>sp|Q09506|TX1B3_CAEEL Tax1-binding protein 3 homolog OS=Caenorhabditis
elegans OX=6239 GN=txbp-3 PE=1 SV=1
Length=124
Score = 48.5 bits (114), Expect = 1e-05, Method: Composition-based stats.
Identities = 17/99 (17%), Positives = 37/99 (37%), Gaps = 4/99 (4%)
Query 230 QEMQLEPITDERVYESIGQYGGETVKIVRIEKARDI---PLGATVRNEMDSVIISRIVKG 286
+ ++ I E + + G+ V + I P A + V I+ + G
Sbjct 10 EAIECLSIAVELHKQEVIDAHGQVTIRVGFKIGGGIDQDPTKAPFKYPDSGVYITNVESG 69
Query 287 GAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMH 325
A+ +G L + D++L++NG + + +
Sbjct 70 SPADVAG-LRKHDKILQVNGADFTMMTHDRAVKFIKQSK 107
>sp|P13115|SRC1_XENLA Tyrosine-protein kinase Src-1 OS=Xenopus
laevis OX=8355 GN=src-a PE=2 SV=4
Length=532
Score = 52.0 bits (123), Expect = 1e-05, Method: Composition-based stats.
Identities = 19/88 (22%), Positives = 33/88 (38%), Gaps = 11/88 (13%)
Query 326 GTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE 385
G + F + + P V A +DY+ E LSF+KG+ L +++
Sbjct 61 GGINFSDTITSPQRTGPLAGGVTTFVALYDYESR-------TETDLSFKKGERLQIVNNT 113
Query 386 DPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
+ +WW A + G +P
Sbjct 114 EGDWWLAR----SLSSGQTGYIPSNYVA 137
>sp|Q9Y566|SHAN1_HUMAN SH3 and multiple ankyrin repeat domains
protein 1 OS=Homo sapiens OX=9606 GN=SHANK1 PE=1 SV=2
Length=2161
Score = 52.4 bits (124), Expect = 1e-05, Method: Composition-based stats.
Identities = 23/129 (18%), Positives = 43/129 (33%), Gaps = 20/129 (16%)
Query 221 LLAHDKVAE-QEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSV- 278
L H V + D S +T V ++K G +R
Sbjct 630 LFRHYTVGSYDSFDAPSLMDGIGPGSDYIIKEKT---VLLQKKDSEGFGFVLRGAKAQTP 686
Query 279 --------------IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
+ + +GG A ++G L GD ++E+NG + +V +++
Sbjct 687 IEEFTPTPAFPALQYLESVDEGGVAWRAG-LRMGDFLIEVNGQNVVKVGHRQVVNMIRQG 745
Query 325 HGTLTFVLI 333
TL ++
Sbjct 746 GNTLMVKVV 754
>sp|P25020|SRC_RSVH1 Tyrosine-protein kinase transforming protein
Src OS=Rous sarcoma virus (strain H-19) OX=11887 GN=V-SRC
PE=1 SV=3
Length=526
Score = 51.6 bits (122), Expect = 2e-05, Method: Composition-based stats.
Identities = 52/293 (18%), Positives = 98/293 (33%), Gaps = 59/293 (20%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ E LSF+KG+ L +++ + +WW A+ G +P
Sbjct 88 ALYDYE-------SWTETDLSFKKGERLQIVNNTEGDWWLAH----SLTTGQTGYIPSNY 136
Query 412 F--------QQQ---REAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDN 460
++ + +++ PE + +K++ + + + D+
Sbjct 137 VAPSDSIQAEEWYFGKITRRESERLLLNPENPRGTFLVRKSETAKGAYCLSVSDFDNAKG 196
Query 461 EEILTYEEMSLYH------QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHT 514
+ Y+ LY L+ + + L RL N V T
Sbjct 197 PNVKHYKICKLYSGGFYITSRTQFGSLQQLVAYYSKHADGLCHRLTN---------VCPT 247
Query 515 TRSRRDQEVAGRDYHFVSRQ--AFEADIAAGKFIE-HGEFEKNLYGTSIDSVRQVINSGK 571
++ + +D + R+ EA + G F E GT+ +++ + G
Sbjct 248 SKPQTQGLA--KDAWEIPRESLRLEAKLGQGCFGEVW---MGTWNGTTRVAIK-TLKPGT 301
Query 572 ---ICLLSLRTQSLKTLRNSDL---------KPYIIFIAPPSQERLRALLAKE 612
L Q +K LR+ L +P I I S+ L L E
Sbjct 302 MSPEAFLQ-EAQVMKKLRHEKLVQLYAVVSEEPIYIVIEYMSKGSLLDFLKGE 353
>sp|Q3SZK8|NHRF1_BOVIN Na(+)/H(+) exchange regulatory cofactor
NHE-RF1 OS=Bos taurus OX=9913 GN=NHERF1 PE=2 SV=1
Length=368
Score = 51.2 bits (121), Expect = 2e-05, Method: Composition-based stats.
Identities = 18/91 (20%), Positives = 36/91 (40%), Gaps = 2/91 (2%)
Query 244 ESIGQYGGETVKIVRIEKA-RDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVL 302
+ G ++ +EK I + G AEKSGLL GD ++
Sbjct 2 SADAGAGAPLPRLCCLEKGPNGYGFHLHGEKGKVGQYIRLVEPGSPAEKSGLL-AGDRLV 60
Query 303 EINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
E+NG + + +V + + ++ +++
Sbjct 61 EVNGENVEKETHQQVVNRIRAALNSVRLLVV 91
Score = 51.2 bits (121), Expect = 2e-05, Method: Composition-based stats.
Identities = 24/153 (16%), Positives = 47/153 (31%), Gaps = 6/153 (4%)
Query 192 EVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGG 251
E L+ + + +E+ P A + + EP Q
Sbjct 94 ETDERLQKLGVQVREEMLRAQEGPGQAEPPAAAAEERGAGGENEPPAAAPEPREAEQSPQ 153
Query 252 ETV----KIVRIEKA-RDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEING 306
E ++ ++K I + AE SG L D ++E+NG
Sbjct 154 ERRELRPRLCAMKKGPNGYGFNLHSDKSKPGQFIRAVDPDSPAEASG-LRAQDRIVEVNG 212
Query 307 IEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
+ + GK EV + +++ + +
Sbjct 213 VCVEGKPHGEVVSAIKAGGDEAKLLVVDRETDE 245
>sp|Q17353|PAR3_CAEEL Partitioning defective protein 3 OS=Caenorhabditis
elegans OX=6239 GN=par-3 PE=1 SV=1
Length=1379
Score = 52.0 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 24/141 (17%), Positives = 48/141 (34%), Gaps = 16/141 (11%)
Query 193 VQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGE 252
+ + +KE +E ++ I L + P+ + S
Sbjct 603 IMSTSASSENKENEETLKVVEEEKIPQKLPL------PALMTPPVPKDTPALSPSGASRF 656
Query 253 TVKIVRIEKARDIPLGATVRNEMD----------SVIISRIVKGGAAEKSGLLHEGDEVL 302
+ I I + LG +++ + + I ++ GGAA K G L D ++
Sbjct 657 EIVIPFINGSSSAGLGVSLKARVSKKSNGSKVDCGIFIKNVMHGGAAFKEGGLRVDDRIV 716
Query 303 EINGIEIRGKDVNEVFDLLSD 323
+ I++ D E L+
Sbjct 717 GVEDIDLEPLDNREAQAALAK 737
Score = 40.8 bits (94), Expect = 0.052, Method: Composition-based stats.
Identities = 23/108 (21%), Positives = 38/108 (35%), Gaps = 7/108 (6%)
Query 237 ITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDS---VIISRIVKGGAAEKSG 293
+ ++ QY G T + I+ + T R I + G A G
Sbjct 497 PIQSALQQANTQYIGHTTVVELIKSSNGFGFTVTGRETAKGERLFYIGTVKPYGVA--LG 554
Query 294 LLHEGDEVLEINGIEIRGKDVNEVFDLLSDM--HGTLTFVLIPSQQIK 339
L GD +LEING +E+ + L + + F++ Q
Sbjct 555 HLKSGDRLLEINGTPTGQWTQSEIVEKLKETMVGEKIKFLVSRVSQSA 602
Score = 36.6 bits (83), Expect = 0.90, Method: Composition-based stats.
Identities = 22/117 (19%), Positives = 44/117 (38%), Gaps = 9/117 (8%)
Query 235 EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGL 294
PI ++ E V +++ ++P G + ++ SV I +I GG K G
Sbjct 385 PPIPEKSENEKQLGIEVNAV----FDESSELP-GTSEPTKLSSVQIMKIEDGGRIAKDGR 439
Query 295 LHEGDEVLEINGIEIRGKD----VNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV 347
+ GD ++ I+G + + DL + +T ++ S +
Sbjct 440 IRVGDCIVAIDGKPVDQMSIIRVRASISDLAAVTSRPVTLIINRSLESFLEQESSAK 496
>sp|Q9Z254|GIPC1_RAT PDZ domain-containing protein GIPC1 OS=Rattus
norvegicus OX=10116 GN=Gipc1 PE=1 SV=2
Length=333
Score = 50.8 bits (120), Expect = 2e-05, Method: Composition-based stats.
Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 6/100 (6%)
Query 254 VKIVRIEKARDIPLGATVRNEMDS-VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
K V + K+ D LG T+ + I RI +G + L+ GD + ING + G
Sbjct 131 RKEVEVFKSED-ALGLTITDNGAGYAFIKRIKEGSVIDHIQLISVGDMIEAINGQSLLGC 189
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKA 352
EV LL ++ TF L ++ P +I ++
Sbjct 190 RHYEVARLLKELPRGRTFTL----KLTEPRKAFDMISQRS 225
>sp|Q5XHY7|STAM2_RAT Signal transducing adapter molecule 2 OS=Rattus
norvegicus OX=10116 GN=Stam2 PE=2 SV=1
Length=523
Score = 51.2 bits (121), Expect = 2e-05, Method: Composition-based stats.
Identities = 23/110 (21%), Positives = 45/110 (41%), Gaps = 18/110 (16%)
Query 305 NGIEI-RGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV----IHVKAHFDYDPS 359
NG + + K+ ++ + ++ + PP + V+A +D++
Sbjct 157 NGASLNKNKEDEDIAKAIELSLQEQKQQYPETKALCPPAESQLSNKVARRVRALYDFEAV 216
Query 360 DDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
+D L+F+ G+I+ V+ D NWW+ +N AGL P
Sbjct 217 EDNE-------LTFKHGEIITVLDDSDANWWEG------ENHRGAGLFPS 253
>sp|O14908|GIPC1_HUMAN PDZ domain-containing protein GIPC1 OS=Homo
sapiens OX=9606 GN=GIPC1 PE=1 SV=2
Length=333
Score = 50.8 bits (120), Expect = 2e-05, Method: Composition-based stats.
Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 6/100 (6%)
Query 254 VKIVRIEKARDIPLGATVRNEMDS-VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
K V + K+ D LG T+ + I RI +G + L+ GD + ING + G
Sbjct 131 RKEVEVFKSED-ALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGC 189
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKA 352
EV LL ++ TF L ++ P +I ++
Sbjct 190 RHYEVARLLKELPRGRTFTL----KLTEPRKAFDMISQRS 225
>sp|Q9P7E8|APP1_SCHPO Protein app1 OS=Schizosaccharomyces pombe
(strain 972 / ATCC 24843) OX=284812 GN=app1 PE=2 SV=1
Length=857
Score = 51.6 bits (122), Expect = 2e-05, Method: Composition-based stats.
Identities = 23/91 (25%), Positives = 34/91 (37%), Gaps = 17/91 (19%)
Query 324 MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVIS 383
T P++ P K VKA +DY +D LSF + +I+ +
Sbjct 783 TGPNETANNPPAEPQAGGPGKS----VKAIYDYQAQEDNE-------LSFFEDEIIANVD 831
Query 384 QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ 414
DPNWW+ G GL P ++
Sbjct 832 CVDPNWWEGECHG------HRGLFPSNYVEE 856
>sp|P13406|FYN_XENLA Tyrosine-protein kinase Fyn OS=Xenopus laevis
OX=8355 GN=fyn PE=2 SV=3
Length=537
Score = 51.2 bits (121), Expect = 2e-05, Method: Composition-based stats.
Identities = 14/62 (23%), Positives = 25/62 (40%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ + LSFQKG+ +++ + +WW+A G +P
Sbjct 89 ALYDYEARTEDD-------LSFQKGEKFQILNSSEGDWWEARSLTTGG----TGYIPSNY 137
Query 412 FQ 413
Sbjct 138 VA 139
>sp|P00528|SRC64_DROME Tyrosine-protein kinase Src64B OS=Drosophila
melanogaster OX=7227 GN=Src64B PE=1 SV=3
Length=552
Score = 51.2 bits (121), Expect = 2e-05, Method: Composition-based stats.
Identities = 29/162 (18%), Positives = 54/162 (33%), Gaps = 11/162 (7%)
Query 321 LSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILH 380
L ++ P P V A +DY D+ LSF KGD +
Sbjct 71 LKIGGKGGVDIIRPRTTPTGVPGVVLKRVVVALYDYKSRDESD-------LSFMKGDRME 123
Query 381 VISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKK 440
VI + +WW+ GL+P ++R + + K +
Sbjct 124 VIDDTESDWWRVV----NLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAE 179
Query 441 NKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPI 482
+ ++ + N + + + +E+ YH R +P+
Sbjct 180 ENPRGTFLVRPSEHNPNGYSLSVKDWEDGRGYHVKHYRIKPL 221
>sp|P54792|DVLP1_HUMAN Putative segment polarity protein dishevelled
homolog DVL1P1 OS=Homo sapiens OX=9606 GN=DVL1P1 PE=5
SV=1
Length=670
Score = 51.6 bits (122), Expect = 2e-05, Method: Composition-based stats.
Identities = 20/102 (20%), Positives = 37/102 (36%), Gaps = 14/102 (14%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD--- 323
+G + + I I+KGGA G + GD +L++N + ++ +L +
Sbjct 267 VGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVS 326
Query 324 MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVP 365
G ++ + P + V P DP P
Sbjct 327 QTGPISLTVAKC----WDPTPRSYFTV-------PRPDPVRP 357
>sp|Q02977|YRK_CHICK Proto-oncogene tyrosine-protein kinase Yrk
OS=Gallus gallus OX=9031 GN=YRK PE=2 SV=2
Length=536
Score = 51.2 bits (121), Expect = 2e-05, Method: Composition-based stats.
Identities = 16/62 (26%), Positives = 27/62 (44%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ + LSFQKG+ H+I+ + +WW+A + G +P
Sbjct 88 ALYDYEARTEDD-------LSFQKGEKFHIINNTEGDWWEAR----SLSSGATGYIPSNY 136
Query 412 FQ 413
Sbjct 137 VA 138
>sp|Q08012|GRAP_DROME Growth factor receptor-bound protein 2 OS=Drosophila
melanogaster OX=7227 GN=drk PE=1 SV=1
Length=211
Score = 49.3 bits (116), Expect = 2e-05, Method: Composition-based stats.
Identities = 19/80 (24%), Positives = 33/80 (41%), Gaps = 7/80 (9%)
Query 329 TFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPN 388
T + SQ +K + V+A +D+ P + L F++GD++ V + D N
Sbjct 136 TASVSRSQDVKLRDMIPEEMLVQALYDFVPQESGE-------LDFRRGDVITVTDRSDEN 188
Query 389 WWQAYREGDEDNQPLAGLVP 408
WW + P + P
Sbjct 189 WWNGEIGNRKGIFPATYVTP 208
>sp|Q6YKA8|DRK_DROSI Protein E(sev)2B OS=Drosophila simulans OX=7240
GN=drk PE=3 SV=1
Length=211
Score = 49.3 bits (116), Expect = 2e-05, Method: Composition-based stats.
Identities = 19/80 (24%), Positives = 33/80 (41%), Gaps = 7/80 (9%)
Query 329 TFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPN 388
T + SQ +K + V+A +D+ P + L F++GD++ V + D N
Sbjct 136 TASVSRSQDVKLRDMIPEEMLVQALYDFVPQESGE-------LDFRRGDVITVTDRSDEN 188
Query 389 WWQAYREGDEDNQPLAGLVP 408
WW + P + P
Sbjct 189 WWNGEIGNRKGIFPATYVTP 208
>sp|P70297|STAM1_MOUSE Signal transducing adapter molecule 1 OS=Mus
musculus OX=10090 GN=Stam PE=1 SV=3
Length=548
Score = 51.2 bits (121), Expect = 2e-05, Method: Composition-based stats.
Identities = 20/79 (25%), Positives = 37/79 (47%), Gaps = 13/79 (16%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
V+A +D++ ++D L+F+ G+I+ V+ DPNWW+ + GL P
Sbjct 215 VRAVYDFEAAEDNE-------LTFKAGEIITVLDDSDPNWWKG------ETHQGVGLFPS 261
Query 410 KSFQQQREAMKQTIEEDKE 428
A + I+ +K+
Sbjct 262 NFVTADLTAEPEMIKTEKK 280
>sp|Q9Z0R4|ITSN1_MOUSE Intersectin-1 OS=Mus musculus OX=10090
GN=Itsn1 PE=1 SV=2
Length=1714
Score = 51.6 bits (122), Expect = 3e-05, Method: Composition-based stats.
Identities = 25/95 (26%), Positives = 40/95 (42%), Gaps = 18/95 (19%)
Query 318 FDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGD 377
LLS +T +P ++P + V +DY +D L+F KG
Sbjct 1126 VKLLSPGTSKITPTELPKTAVQPAVCQ-----VIGMYDYTAQNDDE-------LAFSKGQ 1173
Query 378 ILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSF 412
I++V+++EDP+WW+ G GL P
Sbjct 1174 IINVLNKEDPDWWKGEVSG------QVGLFPSNYV 1202
Score = 35.0 bits (79), Expect = 3.5, Method: Composition-based stats.
Identities = 19/90 (21%), Positives = 39/90 (43%), Gaps = 23/90 (26%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A + Y+ S+ L+FQ+GD++ V++++D +WW GD+ G+ P
Sbjct 1002 AMYTYESSEQGD-------LTFQQGDVI-VVTKKDGDWWTG-TVGDKS-----GVFPSNY 1047
Query 412 FQQQREAMKQTIEEDKEPEKSGKLWCAKKN 441
+ +++ + +GK K
Sbjct 1048 VR---------LKDSEGSGTAGKTGSLGKK 1068
>sp|O14640|DVL1_HUMAN Segment polarity protein dishevelled homolog
DVL-1 OS=Homo sapiens OX=9606 GN=DVL1 PE=1 SV=2
Length=695
Score = 51.2 bits (121), Expect = 3e-05, Method: Composition-based stats.
Identities = 26/145 (18%), Positives = 45/145 (31%), Gaps = 33/145 (23%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD--- 323
+G + + I I+KGGA G + GD +L++N + ++ +L +
Sbjct 267 VGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVS 326
Query 324 MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVIS 383
G ++ + P + V P DP P
Sbjct 327 QTGPISLTVAKC----WDPTPRSYFTV-------PRADPVRPI----------------- 358
Query 384 QEDPNWWQAYREGDEDNQPLAGLVP 408
DP W ++ P G P
Sbjct 359 --DPAAWLSHTAALTGALPRYGTSP 381
>sp|P53669|LIMK1_RAT LIM domain kinase 1 OS=Rattus norvegicus
OX=10116 GN=Limk1 PE=1 SV=1
Length=647
Score = 51.2 bits (121), Expect = 3e-05, Method: Composition-based stats.
Identities = 45/261 (17%), Positives = 92/261 (35%), Gaps = 40/261 (15%)
Query 234 LEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNE------------MDSVIIS 281
+ P+ ++ + +S G + TV +V I + G +V + +V +
Sbjct 143 VTPVIEQILPDSPGSHLPHTVTLVSIPASAHGKRGLSVSIDPPHGPPGCGTEHSHTVRVQ 202
Query 282 RIVKGGAA-EKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI--PSQQI 338
+ G + + +H GD +LEING IR ++E+ L+ + L L P +
Sbjct 203 GVDPGCMSPDVKNSIHIGDRILEINGTPIRNVPLDEIDLLIQETSRLLQLTLEHDPHDSL 262
Query 339 KPPPAKETVIHVKAHFDYDPSDDPY-VPCRELGLSFQKGDILHVISQEDPNWWQAYREGD 397
P + P P P + G S ++ +L S +
Sbjct 263 GHGPVSDPS----------PLASPVHTPSGQAGSSARQKPVLRSCSID------------ 300
Query 398 EDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDD 457
P AG + + Q++ +++ P + + + K A K
Sbjct 301 --TSPGAGSLVSPASQRKDLGRSESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTH 358
Query 458 YDNEEILTYEEMSLYHQPANR 478
+ E++ +E+ + + R
Sbjct 359 RETGEVMVMKELIRFDEETQR 379
>sp|Q4R6G4|NHRF1_MACFA Na(+)/H(+) exchange regulatory cofactor
NHE-RF1 OS=Macaca fascicularis OX=9541 GN=NHERF1 PE=2 SV=1
Length=358
Score = 50.4 bits (119), Expect = 3e-05, Method: Composition-based stats.
Identities = 17/91 (19%), Positives = 34/91 (37%), Gaps = 2/91 (2%)
Query 244 ESIGQYGGETVKIVRIEKA-RDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVL 302
+ G ++ +EK I + G AEK+GLL GD ++
Sbjct 2 SADAAAGAPLPRLCCLEKGPNGYGFHLHGEKGKLGQYIRLVEPGSPAEKAGLL-AGDRLV 60
Query 303 EINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
E+NG + + +V + + +++
Sbjct 61 EVNGENVEKETHQQVVSRIRAALNAVRLLVV 91
Score = 47.0 bits (110), Expect = 4e-04, Method: Composition-based stats.
Identities = 16/103 (16%), Positives = 33/103 (32%), Gaps = 3/103 (3%)
Query 238 TDERVYESIGQYGGETVKIVRIEKA-RDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLH 296
E Q ++ ++K I + AE SG L
Sbjct 137 PREADKSHPEQRKLRP-RLCTMKKGPSGYGFNLHSDKSKPGQFIRSVDPDSPAEASG-LR 194
Query 297 EGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
D ++E+NG+ + GK +V + +++ + +
Sbjct 195 AQDRIVEVNGVCMEGKQHGDVVSAIRAGGDETKLLVVDRETDE 237
>sp|Q9WV48|SHAN1_RAT SH3 and multiple ankyrin repeat domains protein
1 OS=Rattus norvegicus OX=10116 GN=Shank1 PE=1 SV=1
Length=2167
Score = 51.6 bits (122), Expect = 3e-05, Method: Composition-based stats.
Identities = 38/263 (14%), Positives = 82/263 (31%), Gaps = 24/263 (9%)
Query 221 LLAHDKVAE-QEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSV- 278
L H V + D S +T V ++K G +R
Sbjct 630 LFRHYTVGSYDSFDAPSLIDGIDSGSDYIIKEKT---VLLQKKDSEGFGFVLRGAKAQTP 686
Query 279 --------------IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
+ + +GG A ++G L GD ++E+NG + +V +++
Sbjct 687 IEEFTPTPAFPALQYLESVDEGGVAWRAG-LRMGDFLIEVNGQNVVKVGHRQVVNMIRQG 745
Query 325 HGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ 384
TL ++ + P + +H KA P + R ++ + +++ +
Sbjct 746 GNTLMVKVVMVTRH---PDMDEAVHKKASQQAKRLPPPAISLRSKSMTSELEEMVSPWKK 802
Query 385 EDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAK-KNKK 443
+ Q + + + + A +QTI + P G K + K
Sbjct 803 KIEYEQQPAAVPSMEKKRTVYQMALNKLDEILAAAQQTISASESPGPGGLASLGKHRPKG 862
Query 444 KRKKVLYNANKNDDYDNEEILTY 466
+ + + ++
Sbjct 863 FFATESSFDPHHRSQPSYDRPSF 885
>sp|Q7TNF8|RIMB1_MOUSE Peripheral-type benzodiazepine receptor-associated
protein 1 OS=Mus musculus OX=10090 GN=Tspoap1 PE=2
SV=2
Length=1846
Score = 51.6 bits (122), Expect = 3e-05, Method: Composition-based stats.
Identities = 33/191 (17%), Positives = 66/191 (35%), Gaps = 20/191 (10%)
Query 237 ITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNE--MDSVIISRIVKGGAAEKSGL 294
+ E + G+ +K+ + A G + + +++ + A + L
Sbjct 1634 PNPDAGEEELPFKEGQLLKVFGDKDADGFYRGESGGRTGYIPCNMVAEVAVDSPAGRQQL 1693
Query 295 LHEG----DEVLEI--NGIEIRGKDVNEVFDLLSDMHGTLTF----VLIPSQ-QIKPPPA 343
L G + + E NG + + L P ++ A
Sbjct 1694 LQRGFLPPNVLTEASGNGPSVYSSAHTPGPPPKPRRSKKVELEGPTQLCPGPPKLIHSAA 1753
Query 344 KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVI-SQEDPNWWQAYREGDEDNQP 402
++T + A FDY+P ++ E L F+ GD++ V + +D ++ G
Sbjct 1754 QKTSRPMVAAFDYNPRENSPNMDVEAELPFRAGDVITVFGNMDDDGFYYGELNG------ 1807
Query 403 LAGLVPGKSFQ 413
GLVP +
Sbjct 1808 QRGLVPSNFLE 1818
Score = 40.8 bits (94), Expect = 0.049, Method: Composition-based stats.
Identities = 27/114 (24%), Positives = 43/114 (38%), Gaps = 8/114 (7%)
Query 303 EINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHV-KAHFDYDP-SD 360
E G + G+ + GT P + PP ++ + V A FDYDP S
Sbjct 1574 ESRGQDNSGRRGPQRRGARVPRSGTTELA-PPRSPQEAPPHQDLPVRVFVALFDYDPVSM 1632
Query 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ 414
P E L F++G +L V +D + + G+ G +P +
Sbjct 1633 SPNPDAGEEELPFKEGQLLKVFGDKDAD---GFYRGESGG--RTGYIPCNMVAE 1681
>sp|D3YZU1|SHAN1_MOUSE SH3 and multiple ankyrin repeat domains
protein 1 OS=Mus musculus OX=10090 GN=Shank1 PE=1 SV=1
Length=2167
Score = 51.6 bits (122), Expect = 3e-05, Method: Composition-based stats.
Identities = 38/263 (14%), Positives = 82/263 (31%), Gaps = 24/263 (9%)
Query 221 LLAHDKVAE-QEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSV- 278
L H V + D S +T V ++K G +R
Sbjct 630 LFRHYTVGSYDSFDAPSLIDGIDSGSDYIIKEKT---VLLQKKDSEGFGFVLRGAKAQTP 686
Query 279 --------------IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
+ + +GG A ++G L GD ++E+NG + +V +++
Sbjct 687 IEEFTPTPAFPALQYLESVDEGGVAWRAG-LRMGDFLIEVNGQNVVKVGHRQVVNMIRQG 745
Query 325 HGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ 384
TL ++ + P + +H KA P + R ++ + +++ +
Sbjct 746 GNTLMVKVVMVTRH---PDMDEAVHKKASQQAKRLPPPAISLRSKSMTSELEEMVSPWKK 802
Query 385 EDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAK-KNKK 443
+ Q + + + + A +QTI + P G K + K
Sbjct 803 KIEYEQQPAAVPSMEKKRTVYQMALNKLDEILAAAQQTISASESPGPGGLASLGKHRPKG 862
Query 444 KRKKVLYNANKNDDYDNEEILTY 466
+ + + ++
Sbjct 863 FFATESSFDPHHRSQPSYDRPSF 885
>sp|O14745|NHRF1_HUMAN Na(+)/H(+) exchange regulatory cofactor
NHE-RF1 OS=Homo sapiens OX=9606 GN=NHERF1 PE=1 SV=4
Length=358
Score = 50.4 bits (119), Expect = 3e-05, Method: Composition-based stats.
Identities = 17/91 (19%), Positives = 34/91 (37%), Gaps = 2/91 (2%)
Query 244 ESIGQYGGETVKIVRIEKA-RDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVL 302
+ G ++ +EK I + G AEK+GLL GD ++
Sbjct 2 SADAAAGAPLPRLCCLEKGPNGYGFHLHGEKGKLGQYIRLVEPGSPAEKAGLL-AGDRLV 60
Query 303 EINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
E+NG + + +V + + +++
Sbjct 61 EVNGENVEKETHQQVVSRIRAALNAVRLLVV 91
Score = 49.7 bits (117), Expect = 5e-05, Method: Composition-based stats.
Identities = 22/146 (15%), Positives = 46/146 (32%), Gaps = 10/146 (7%)
Query 203 KEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETV-------- 254
E E L + LL A + + E E+ + ++
Sbjct 93 PETDEQLQKLGVQVREELLRAQEAPGQAEPPAAAEVQGAGNENEPREADKSHPEQRELRP 152
Query 255 KIVRIEKA-RDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
++ ++K I + AE SG L D ++E+NG+ + GK
Sbjct 153 RLCTMKKGPSGYGFNLHSDKSKPGQFIRSVDPDSPAEASG-LRAQDRIVEVNGVCMEGKQ 211
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIK 339
+V + +++ + +
Sbjct 212 HGDVVSAIRAGGDETKLLVVDRETDE 237
>sp|Q9NZM3|ITSN2_HUMAN Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2
PE=1 SV=3
Length=1697
Score = 51.2 bits (121), Expect = 3e-05, Method: Composition-based stats.
Identities = 24/83 (29%), Positives = 38/83 (46%), Gaps = 13/83 (16%)
Query 330 FVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNW 389
L+ + PA V V A +DY ++ E LSF KG +++V++++DP+W
Sbjct 1112 VKLLGPSSERATPAFHPVCQVIAMYDYAANN-------EDELSFSKGQLINVMNKDDPDW 1164
Query 390 WQAYREGDEDNQPLAGLVPGKSF 412
WQ G + GL P
Sbjct 1165 WQGEING------VTGLFPSNYV 1181
>sp|P51141|DVL1_MOUSE Segment polarity protein dishevelled homolog
DVL-1 OS=Mus musculus OX=10090 GN=Dvl1 PE=1 SV=2
Length=695
Score = 50.8 bits (120), Expect = 3e-05, Method: Composition-based stats.
Identities = 25/145 (17%), Positives = 45/145 (31%), Gaps = 33/145 (23%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD--- 323
+G + + I I+KGGA G + GD +L++N + ++ +L +
Sbjct 267 VGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVS 326
Query 324 MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVIS 383
G ++ + P + + P DP P
Sbjct 327 QTGPISLTVAKC----WDPTPRSYFTI-------PRADPVRPI----------------- 358
Query 384 QEDPNWWQAYREGDEDNQPLAGLVP 408
DP W ++ P G P
Sbjct 359 --DPAAWLSHTAALTGALPRYGTSP 381
>sp|Q9JMH9|MY18A_MOUSE Unconventional myosin-XVIIIa OS=Mus musculus
OX=10090 GN=Myo18a PE=1 SV=2
Length=2050
Score = 51.2 bits (121), Expect = 3e-05, Method: Composition-based stats.
Identities = 12/68 (18%), Positives = 29/68 (43%), Gaps = 1/68 (1%)
Query 279 IISRIVKG-GAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
++ G G + + L GD ++EING + K +E+ +++ ++ + P +
Sbjct 253 VVHFAEPGAGTKDLALGLVPGDRLVEINGQNVENKSRDEIVEMIRQSGDSVRLKVQPIPE 312
Query 338 IKPPPAKE 345
+
Sbjct 313 LSELSRSW 320
>sp|Q5IS48|DVL1_PANTR Segment polarity protein dishevelled homolog
DVL-1 OS=Pan troglodytes OX=9598 GN=DVL1 PE=2 SV=1
Length=670
Score = 50.8 bits (120), Expect = 3e-05, Method: Composition-based stats.
Identities = 20/102 (20%), Positives = 37/102 (36%), Gaps = 14/102 (14%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD--- 323
+G + + I I+KGGA G + GD +L++N + ++ +L +
Sbjct 267 VGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVS 326
Query 324 MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVP 365
G ++ + P + V P DP P
Sbjct 327 QTGPISLTVAKC----WDPTPRSYFTV-------PRADPVRP 357
>sp|D3ZFD0|MY18A_RAT Unconventional myosin-XVIIIa OS=Rattus norvegicus
OX=10116 GN=Myo18a PE=1 SV=2
Length=2044
Score = 51.2 bits (121), Expect = 3e-05, Method: Composition-based stats.
Identities = 12/68 (18%), Positives = 29/68 (43%), Gaps = 1/68 (1%)
Query 279 IISRIVKG-GAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
++ G G + + L GD ++EING + K +E+ +++ ++ + P +
Sbjct 253 VVHFAEPGAGTKDLALGLVPGDRLVEINGQNVENKSRDEIVEMIRQSGDSVRLKVQPIPE 312
Query 338 IKPPPAKE 345
+
Sbjct 313 LSELSRSW 320
>sp|Q5JV73|FRPD3_HUMAN FERM and PDZ domain-containing protein
3 OS=Homo sapiens OX=9606 GN=FRMPD3 PE=2 SV=3
Length=1777
Score = 51.2 bits (121), Expect = 4e-05, Method: Composition-based stats.
Identities = 16/104 (15%), Positives = 38/104 (37%), Gaps = 3/104 (3%)
Query 239 DERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEG 298
+ Q E ++ V + + G +E V++ + GG +E L G
Sbjct 4 ESANDMECEQLPAEILRQVTVHRDPIYGFGFVAGSE-RPVVVRSVRPGGPSEN--KLLAG 60
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPP 342
D+++ IN ++ + +L+ + ++ + Q
Sbjct 61 DQIVAINEEDVSEAPRERLIELIRSAKEFIVLTVLHTHQSPKSA 104
>sp|Q9WVB9|DVL1_RAT Segment polarity protein dishevelled homolog
DVL-1 OS=Rattus norvegicus OX=10116 GN=Dvl1 PE=1 SV=3
Length=695
Score = 50.8 bits (120), Expect = 4e-05, Method: Composition-based stats.
Identities = 25/145 (17%), Positives = 45/145 (31%), Gaps = 33/145 (23%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD--- 323
+G + + I I+KGGA G + GD +L++N + ++ +L +
Sbjct 267 VGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVLREIVS 326
Query 324 MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVIS 383
G ++ + P + + P DP P
Sbjct 327 QTGPISLTVAKC----WDPTPRSYFTI-------PRADPVRPI----------------- 358
Query 384 QEDPNWWQAYREGDEDNQPLAGLVP 408
DP W ++ P G P
Sbjct 359 --DPAAWLSHTAALTGALPRYGTSP 381
>sp|O93436|STAM2_CHICK Signal transducing adapter molecule 2 OS=Gallus
gallus OX=9031 GN=STAM2 PE=1 SV=1
Length=468
Score = 50.4 bits (119), Expect = 4e-05, Method: Composition-based stats.
Identities = 24/115 (21%), Positives = 45/115 (39%), Gaps = 22/115 (19%)
Query 305 NGIEI-RGKDVNEVFDLL------SDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYD 357
NG + + K+ ++ + T L PS +I+ V+A +D++
Sbjct 156 NGSSLSKNKEDEDIRKAIELSLQEQKQQQMETKSLYPSAEIQQTNQNLRK--VRALYDFE 213
Query 358 PSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSF 412
+D L+F+ G+I+ V+ D +WW+ +N GL P
Sbjct 214 AVEDNE-------LTFKSGEIIFVLDDSDTDWWKG------ENHRGVGLFPSNFV 255
>sp|Q6ZWJ1|STXB4_HUMAN Syntaxin-binding protein 4 OS=Homo sapiens
OX=9606 GN=STXBP4 PE=1 SV=2
Length=553
Score = 50.4 bits (119), Expect = 4e-05, Method: Composition-based stats.
Identities = 25/116 (22%), Positives = 42/116 (36%), Gaps = 8/116 (7%)
Query 252 ETVKIVRIEKARDIPL---GATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIE 308
+++ I K + L G RNE V I I+ GG K G L GD+++ +N
Sbjct 18 PAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKES 77
Query 309 IRGKDVNEVFDLLSDMHGTLTFV-----LIPSQQIKPPPAKETVIHVKAHFDYDPS 359
+ G E +++ L + P ++A +Y P
Sbjct 78 MIGVSFEEAKSIITGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQ 133
>sp|Q9WVE9|ITSN1_RAT Intersectin-1 OS=Rattus norvegicus OX=10116
GN=Itsn1 PE=1 SV=2
Length=1713
Score = 50.8 bits (120), Expect = 4e-05, Method: Composition-based stats.
Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 18/95 (19%)
Query 318 FDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGD 377
LLS +T +P ++P + V +DY +D L+F KG
Sbjct 1125 VKLLSPGTSKITPTELPKTAVQPAVCQ-----VIGMYDYTAQNDDE-------LAFSKGQ 1172
Query 378 ILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSF 412
I++V+S+EDP+WW+ G GL P
Sbjct 1173 IINVLSKEDPDWWKGEVSG------QVGLFPSNYV 1201
Score = 34.6 bits (78), Expect = 4.2, Method: Composition-based stats.
Identities = 17/90 (19%), Positives = 37/90 (41%), Gaps = 23/90 (26%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A + Y+ S+ L+FQ+GD++ V++++D +WW +G+ P
Sbjct 1001 AMYTYESSEHGD-------LTFQQGDVI-VVTKKDGDWWTGTV------GETSGVFPSNY 1046
Query 412 FQQQREAMKQTIEEDKEPEKSGKLWCAKKN 441
+ +++ + +GK K
Sbjct 1047 VR---------LKDSEGSGTAGKTGSLGKK 1067
>sp|Q61062|DVL3_MOUSE Segment polarity protein dishevelled homolog
DVL-3 OS=Mus musculus OX=10090 GN=Dvl3 PE=1 SV=2
Length=716
Score = 50.4 bits (119), Expect = 4e-05, Method: Composition-based stats.
Identities = 17/80 (21%), Positives = 31/80 (39%), Gaps = 3/80 (4%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD--- 323
+G + + I I+KGGA G + GD +L++N I ++ +L +
Sbjct 265 VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVH 324
Query 324 MHGTLTFVLIPSQQIKPPPA 343
G +T + P
Sbjct 325 KPGPITLTVAKCWDPSPRGC 344
>sp|Q92997|DVL3_HUMAN Segment polarity protein dishevelled homolog
DVL-3 OS=Homo sapiens OX=9606 GN=DVL3 PE=1 SV=2
Length=716
Score = 50.4 bits (119), Expect = 4e-05, Method: Composition-based stats.
Identities = 17/80 (21%), Positives = 31/80 (39%), Gaps = 3/80 (4%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD--- 323
+G + + I I+KGGA G + GD +L++N I ++ +L +
Sbjct 265 VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVH 324
Query 324 MHGTLTFVLIPSQQIKPPPA 343
G +T + P
Sbjct 325 KPGPITLTVAKCWDPSPRGC 344
>sp|O01498|STAM1_CAEEL Signal transducing adapter molecule 1 OS=Caenorhabditis
elegans OX=6239 GN=stam-1 PE=1 SV=2
Length=457
Score = 50.1 bits (118), Expect = 4e-05, Method: Composition-based stats.
Identities = 24/125 (19%), Positives = 47/125 (38%), Gaps = 13/125 (10%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
V+A +D++ ++ LSF GDI+ + + +P+WW GL P
Sbjct 224 VRALYDFEAAESNE-------LSFVAGDIITITDESNPHWWTGR------IGTQQGLFPS 270
Query 410 KSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEM 469
Q + +K + + + + +VL+ + + + E L E
Sbjct 271 SFVTNQLDDLKSKETDSSQKAPEVVASINEAILVRCLQVLHECDPTGERQDPEDLAQLEA 330
Query 470 SLYHQ 474
+ Y Q
Sbjct 331 ASYAQ 335
>sp|Q6EWH2|FYNA_DANRE Tyrosine-protein kinase fyna OS=Danio rerio
OX=7955 GN=fyna PE=1 SV=2
Length=537
Score = 50.4 bits (119), Expect = 5e-05, Method: Composition-based stats.
Identities = 13/62 (21%), Positives = 25/62 (40%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ + LSF+KG+ +++ + +WW+A G +P
Sbjct 89 ALYDYEARSEDD-------LSFRKGEKFQILNSTEGDWWEARSLTTGG----TGYIPSNY 137
Query 412 FQ 413
Sbjct 138 VA 139
>sp|P09324|YES_CHICK Tyrosine-protein kinase Yes OS=Gallus gallus
OX=9031 GN=YES1 PE=1 SV=3
Length=541
Score = 50.4 bits (119), Expect = 5e-05, Method: Composition-based stats.
Identities = 16/74 (22%), Positives = 26/74 (35%), Gaps = 11/74 (15%)
Query 340 PPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDED 399
P V A +DY+ LSF+KG+ +I+ + +WW+A
Sbjct 84 PSTLTGGVTVFVALYDYEARTTDD-------LSFKKGERFQIINNTEGDWWEARSI---- 132
Query 400 NQPLAGLVPGKSFQ 413
G +P
Sbjct 133 ATGKTGYIPSNYVA 146
>sp|Q05AS8|DVL2_XENTR Segment polarity protein dishevelled homolog
DVL-2 OS=Xenopus tropicalis OX=8364 GN=dvl2 PE=2 SV=1
Length=732
Score = 50.4 bits (119), Expect = 5e-05, Method: Composition-based stats.
Identities = 21/109 (19%), Positives = 38/109 (35%), Gaps = 7/109 (6%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD--- 323
+G + + I I+KGGA G + GD +L++N I ++ +L D
Sbjct 266 VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDINFENMSNDDAVRVLRDIVH 325
Query 324 MHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLS 372
G + + P+ + + + P D LS
Sbjct 326 KPGPIILTVAKC----WDPSPQGYFTLPRNEPIQPIDPAAWVSHSAALS 370
>sp|Q8MR31|SLIP1_DROME Slo-interacting protein 1 OS=Drosophila
melanogaster OX=7227 GN=Slip1 PE=1 SV=2
Length=767
Score = 50.4 bits (119), Expect = 5e-05, Method: Composition-based stats.
Identities = 36/199 (18%), Positives = 72/199 (36%), Gaps = 31/199 (16%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+ V IS + A + G L +GD++L ING++++ + E+ ++ ++T ++
Sbjct 222 EDVFISGVQPESIAYRDGRLRQGDQILRINGLDVKNQ--EELETQIARSSTSVTLLVS-- 277
Query 336 QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYRE 395
+ + D DD E +F D +V+ + D +
Sbjct 278 ---------------RILYPED--DDDEDIHFEYANTFLPDDYTNVVDKLDKVLLTHVKS 320
Query 396 GDEDNQPLA------GLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVL 449
+E + A +P K+ + + K + C+K + +
Sbjct 321 LEELSNKSAMQSDECYHIPEKNSSD---SNVKISSLAKNIIEQSTKSCSKIKLRPNANLD 377
Query 450 YNANKNDDYDNEEI-LTYE 467
Y N EE+ L YE
Sbjct 378 YKKKFNLPLSQEEVHLQYE 396
>sp|Q9CX99|GRAP_MOUSE GRB2-related adapter protein OS=Mus musculus
OX=10090 GN=Grap PE=1 SV=1
Length=217
Score = 48.5 bits (114), Expect = 5e-05, Method: Composition-based stats.
Identities = 19/72 (26%), Positives = 31/72 (43%), Gaps = 7/72 (10%)
Query 337 QIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREG 396
+P +A FD+ D LS ++GDI+ V+ +EDP+WW+ G
Sbjct 150 DEQPLIKPSRACFAQAQFDFSAQDPSQ-------LSLRRGDIVEVVEREDPHWWRGRAGG 202
Query 397 DEDNQPLAGLVP 408
P + + P
Sbjct 203 RLGFFPRSYVQP 214
>sp|P05480|SRC_MOUSE Proto-oncogene tyrosine-protein kinase Src
OS=Mus musculus OX=10090 GN=Src PE=1 SV=5
Length=535
Score = 50.1 bits (118), Expect = 5e-05, Method: Composition-based stats.
Identities = 17/78 (22%), Positives = 30/78 (38%), Gaps = 11/78 (14%)
Query 336 QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYRE 395
+ P V A +DY+ E LSF+KG+ L +++ + +WW A+
Sbjct 74 SPQRAGPLAGGVTTFVALYDYESR-------TETDLSFKKGERLQIVNNTEGDWWLAH-- 124
Query 396 GDEDNQPLAGLVPGKSFQ 413
+ G +P
Sbjct 125 --SLSTGQTGYIPSNYVA 140
>sp|Q9WUD9|SRC_RAT Proto-oncogene tyrosine-protein kinase Src
OS=Rattus norvegicus OX=10116 GN=Src PE=1 SV=4
Length=536
Score = 50.1 bits (118), Expect = 5e-05, Method: Composition-based stats.
Identities = 17/78 (22%), Positives = 30/78 (38%), Gaps = 11/78 (14%)
Query 336 QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYRE 395
+ P V A +DY+ E LSF+KG+ L +++ + +WW A+
Sbjct 75 SPQRAGPLAGGVTTFVALYDYESR-------TETDLSFKKGERLQIVNNTEGDWWLAH-- 125
Query 396 GDEDNQPLAGLVPGKSFQ 413
+ G +P
Sbjct 126 --SLSTGQTGYIPSNYVA 141
>sp|P12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src
OS=Homo sapiens OX=9606 GN=SRC PE=1 SV=3
Length=536
Score = 50.1 bits (118), Expect = 5e-05, Method: Composition-based stats.
Identities = 17/78 (22%), Positives = 30/78 (38%), Gaps = 11/78 (14%)
Query 336 QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYRE 395
+ P V A +DY+ E LSF+KG+ L +++ + +WW A+
Sbjct 75 SPQRAGPLAGGVTTFVALYDYESR-------TETDLSFKKGERLQIVNNTEGDWWLAH-- 125
Query 396 GDEDNQPLAGLVPGKSFQ 413
+ G +P
Sbjct 126 --SLSTGQTGYIPSNYVA 141
>sp|P17713|STK_HYDVU Tyrosine-protein kinase STK OS=Hydra vulgaris
OX=6087 GN=STK PE=2 SV=1
Length=509
Score = 50.1 bits (118), Expect = 5e-05, Method: Composition-based stats.
Identities = 24/121 (20%), Positives = 40/121 (33%), Gaps = 19/121 (16%)
Query 300 EVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPP-------PAKETVIHVKA 352
+ +N + K + V + T ++ +PP I V A
Sbjct 8 QTKALNNQPDKSKSKDVVLKENTSPFSQNTNNIMHVSHNQPPNINPPMLGGPGVTIFV-A 66
Query 353 HFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSF 412
+DY+ LSF+KG+ L +I+ D +WW A G +P
Sbjct 67 LYDYEARISED-------LSFKKGERLQIINTADGDWWYARSLITNSE----GYIPSTYV 115
Query 413 Q 413
Sbjct 116 A 116
>sp|Q9Z1T4|CNKR2_RAT Connector enhancer of kinase suppressor of
ras 2 OS=Rattus norvegicus OX=10116 GN=Cnksr2 PE=1 SV=1
Length=1032
Score = 50.4 bits (119), Expect = 5e-05, Method: Composition-based stats.
Identities = 19/121 (16%), Positives = 47/121 (39%), Gaps = 8/121 (7%)
Query 264 DIPLGATVRNEMDSV-IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
LG +++ D + +I+ + A++ +H GDEV+++N + G + + + L
Sbjct 224 SEGLGMYIKSTYDGLHVITGTTENSPADRCKKIHAGDEVIQVNHQTVVGWQLKNLVNALR 283
Query 323 DMHGTL--TFVLIPSQQIKPPPA-----KETVIHVKAHFDYDPSDDPYVPCRELGLSFQK 375
+ + T P + PA + + ++ P+ P + ++
Sbjct 284 EDPSGVILTLKKRPQSMLTSAPALLKNMRWKPLALQPLIPRSPTSSVATPSSTISTPTKR 343
Query 376 G 376
Sbjct 344 D 344
>sp|Q80YA9|CNKR2_MOUSE Connector enhancer of kinase suppressor
of ras 2 OS=Mus musculus OX=10090 GN=Cnksr2 PE=1 SV=1
Length=1032
Score = 50.4 bits (119), Expect = 5e-05, Method: Composition-based stats.
Identities = 19/121 (16%), Positives = 47/121 (39%), Gaps = 8/121 (7%)
Query 264 DIPLGATVRNEMDSV-IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
LG +++ D + +I+ + A++ +H GDEV+++N + G + + + L
Sbjct 224 SEGLGMYIKSTYDGLHVITGTTENSPADRCKKIHAGDEVIQVNHQTVVGWQLKNLVNALR 283
Query 323 DMHGTL--TFVLIPSQQIKPPPA-----KETVIHVKAHFDYDPSDDPYVPCRELGLSFQK 375
+ + T P + PA + + ++ P+ P + ++
Sbjct 284 EDPSGVILTLKKRPQSMLTSAPALLKNMRWKPLALQPLIPRSPTSSVATPSSTISTPTKR 343
Query 376 G 376
Sbjct 344 D 344
>sp|Q8WXI2|CNKR2_HUMAN Connector enhancer of kinase suppressor
of ras 2 OS=Homo sapiens OX=9606 GN=CNKSR2 PE=1 SV=1
Length=1034
Score = 50.4 bits (119), Expect = 5e-05, Method: Composition-based stats.
Identities = 19/121 (16%), Positives = 47/121 (39%), Gaps = 8/121 (7%)
Query 264 DIPLGATVRNEMDSV-IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
LG +++ D + +I+ + A++ +H GDEV+++N + G + + + L
Sbjct 224 SEGLGMYIKSTYDGLHVITGTTENSPADRCKKIHAGDEVIQVNHQTVVGWQLKNLVNALR 283
Query 323 DMHGTL--TFVLIPSQQIKPPPA-----KETVIHVKAHFDYDPSDDPYVPCRELGLSFQK 375
+ + T P + PA + + ++ P+ P + ++
Sbjct 284 EDPSGVILTLKKRPQSMLTSAPALLKNMRWKPLALQPLIPRSPTSSVATPSSTISTPTKR 343
Query 376 G 376
Sbjct 344 D 344
>sp|P51142|DVL2_XENLA Segment polarity protein dishevelled homolog
DVL-2 OS=Xenopus laevis OX=8355 GN=dvl2 PE=1 SV=1
Length=736
Score = 50.1 bits (118), Expect = 6e-05, Method: Composition-based stats.
Identities = 17/78 (22%), Positives = 30/78 (38%), Gaps = 3/78 (4%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD--- 323
+G + + I I+KGGA G + GD +L++N I ++ +L D
Sbjct 270 VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDINFENMSNDDAVRVLRDIVH 329
Query 324 MHGTLTFVLIPSQQIKPP 341
G + + P
Sbjct 330 KPGPIVLTVAKCWDPSPQ 347
>sp|A7E8B6|SLA1_SCLS1 Actin cytoskeleton-regulatory complex protein
sla1 OS=Sclerotinia sclerotiorum (strain ATCC 18683 /
1980 / Ss-1) OX=665079 GN=sla1 PE=3 SV=2
Length=1150
Score = 50.4 bits (119), Expect = 6e-05, Method: Composition-based stats.
Identities = 19/55 (35%), Positives = 32/55 (58%), Gaps = 2/55 (4%)
Query 362 PYVPCRELGLSFQKGDILHVISQE-DPNWWQAYREGD-EDNQPLAGLVPGKSFQQ 414
YVP E L+ ++GDIL+V+ + + +WW+A ++ ED GL+P Q+
Sbjct 12 DYVPAGEGELTIKEGDILYVLEKSTEDDWWKAKKKASAEDEDEPVGLIPNNYIQE 66
>sp|Q1JPZ3|SRC_DANRE Proto-oncogene tyrosine-protein kinase Src
OS=Danio rerio OX=7955 GN=src PE=1 SV=2
Length=534
Score = 50.1 bits (118), Expect = 6e-05, Method: Composition-based stats.
Identities = 14/62 (23%), Positives = 25/62 (40%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ LSF+KG+ L +++ + +WW A +G +P
Sbjct 89 ALYDYESRTASD-------LSFRKGERLQIVNNTEGDWWLAR----SLTTGESGYIPSNY 137
Query 412 FQ 413
Sbjct 138 VA 139
>sp|Q05876|FYN_CHICK Tyrosine-protein kinase Fyn OS=Gallus gallus
OX=9031 GN=FYN PE=1 SV=2
Length=534
Score = 50.1 bits (118), Expect = 6e-05, Method: Composition-based stats.
Identities = 13/62 (21%), Positives = 24/62 (39%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ + LSF KG+ +++ + +WW+A G +P
Sbjct 89 ALYDYEARTEDD-------LSFHKGEKFQILNSSEGDWWEAR----SLTTGETGYIPSNY 137
Query 412 FQ 413
Sbjct 138 VA 139
>sp|O14641|DVL2_HUMAN Segment polarity protein dishevelled homolog
DVL-2 OS=Homo sapiens OX=9606 GN=DVL2 PE=1 SV=1
Length=736
Score = 50.1 bits (118), Expect = 6e-05, Method: Composition-based stats.
Identities = 16/80 (20%), Positives = 30/80 (38%), Gaps = 3/80 (4%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD--- 323
+G + + I I+KGGA G + GD +L++N + ++ +L D
Sbjct 283 VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVH 342
Query 324 MHGTLTFVLIPSQQIKPPPA 343
G + + P
Sbjct 343 KPGPIVLTVAKCWDPSPQAY 362
>sp|Q62844|FYN_RAT Tyrosine-protein kinase Fyn OS=Rattus norvegicus
OX=10116 GN=Fyn PE=1 SV=1
Length=537
Score = 50.1 bits (118), Expect = 6e-05, Method: Composition-based stats.
Identities = 13/62 (21%), Positives = 24/62 (39%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ + LSF KG+ +++ + +WW+A G +P
Sbjct 89 ALYDYEARTEDD-------LSFHKGEKFQILNSSEGDWWEAR----SLTTGETGYIPSNY 137
Query 412 FQ 413
Sbjct 138 VA 139
>sp|A1Y2K1|FYN_PIG Tyrosine-protein kinase Fyn OS=Sus scrofa OX=9823
GN=FYN PE=2 SV=2
Length=537
Score = 50.1 bits (118), Expect = 6e-05, Method: Composition-based stats.
Identities = 13/62 (21%), Positives = 24/62 (39%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ + LSF KG+ +++ + +WW+A G +P
Sbjct 89 ALYDYEARTEDD-------LSFHKGEKFQILNSSEGDWWEAR----SLTTGETGYIPSNY 137
Query 412 FQ 413
Sbjct 138 VA 139
>sp|P39688|FYN_MOUSE Tyrosine-protein kinase Fyn OS=Mus musculus
OX=10090 GN=Fyn PE=1 SV=4
Length=537
Score = 50.1 bits (118), Expect = 6e-05, Method: Composition-based stats.
Identities = 13/62 (21%), Positives = 24/62 (39%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ + LSF KG+ +++ + +WW+A G +P
Sbjct 89 ALYDYEARTEDD-------LSFHKGEKFQILNSSEGDWWEAR----SLTTGETGYIPSNY 137
Query 412 FQ 413
Sbjct 138 VA 139
>sp|P06241|FYN_HUMAN Tyrosine-protein kinase Fyn OS=Homo sapiens
OX=9606 GN=FYN PE=1 SV=3
Length=537
Score = 50.1 bits (118), Expect = 6e-05, Method: Composition-based stats.
Identities = 13/62 (21%), Positives = 24/62 (39%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ + LSF KG+ +++ + +WW+A G +P
Sbjct 89 ALYDYEARTEDD-------LSFHKGEKFQILNSSEGDWWEAR----SLTTGETGYIPSNY 137
Query 412 FQ 413
Sbjct 138 VA 139
>sp|A0JNB0|FYN_BOVIN Tyrosine-protein kinase Fyn OS=Bos taurus
OX=9913 GN=FYN PE=2 SV=1
Length=537
Score = 50.1 bits (118), Expect = 6e-05, Method: Composition-based stats.
Identities = 13/62 (21%), Positives = 24/62 (39%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ + LSF KG+ +++ + +WW+A G +P
Sbjct 89 ALYDYEARTEDD-------LSFHKGEKFQILNSSEGDWWEAR----SLTTGETGYIPSNY 137
Query 412 FQ 413
Sbjct 138 VA 139
>sp|F1RDG9|FYNB_DANRE Tyrosine-protein kinase fynb OS=Danio rerio
OX=7955 GN=fynb PE=2 SV=1
Length=544
Score = 50.1 bits (118), Expect = 6e-05, Method: Composition-based stats.
Identities = 14/62 (23%), Positives = 24/62 (39%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ + LSF+KG+ +I+ + +WW A G +P
Sbjct 96 ALYDYEARTEDD-------LSFRKGEKFQIINSTEGDWWDARSLTTGG----TGYIPSNY 144
Query 412 FQ 413
Sbjct 145 VA 146
>sp|Q96JH8|RADIL_HUMAN Ras-associating and dilute domain-containing
protein OS=Homo sapiens OX=9606 GN=RADIL PE=1 SV=5
Length=1075
Score = 50.1 bits (118), Expect = 7e-05, Method: Composition-based stats.
Identities = 19/85 (22%), Positives = 33/85 (39%), Gaps = 5/85 (6%)
Query 257 VRIEKA-RDIPLGATVRNEMD----SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
V +E+ + +G + I ++ G A G L GD +LE+NG + G
Sbjct 977 VELERGPSGLGMGLIDGMHTHLGAPGLYIQTLLPGSPAAADGRLSLGDRILEVNGSSLLG 1036
Query 312 KDVNEVFDLLSDMHGTLTFVLIPSQ 336
DL+ + F++ S
Sbjct 1037 LGYLRAVDLIRHGGKKMRFLVAKSD 1061
>sp|Q60838|DVL2_MOUSE Segment polarity protein dishevelled homolog
DVL-2 OS=Mus musculus OX=10090 GN=Dvl2 PE=1 SV=2
Length=736
Score = 50.1 bits (118), Expect = 7e-05, Method: Composition-based stats.
Identities = 16/80 (20%), Positives = 30/80 (38%), Gaps = 3/80 (4%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD--- 323
+G + + I I+KGGA G + GD +L++N + ++ +L D
Sbjct 283 VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVH 342
Query 324 MHGTLTFVLIPSQQIKPPPA 343
G + + P
Sbjct 343 KPGPIVLTVAKCWDPSPQAY 362
>sp|Q9WV89|STXB4_MOUSE Syntaxin-binding protein 4 OS=Mus musculus
OX=10090 GN=Stxbp4 PE=1 SV=1
Length=557
Score = 49.7 bits (117), Expect = 7e-05, Method: Composition-based stats.
Identities = 19/77 (25%), Positives = 33/77 (43%), Gaps = 3/77 (4%)
Query 252 ETVKIVRIEKARDIPL---GATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIE 308
+++ + K + L G RNE V I ++ GG K G L GD+++ IN
Sbjct 18 PAFRVITVTKETGLGLKILGGINRNEGPLVYIHEVIPGGDCYKDGRLKPGDQLVSINKES 77
Query 309 IRGKDVNEVFDLLSDMH 325
+ G E +++
Sbjct 78 MIGVSFEEAKSIITRAK 94
>sp|Q10199|IMP2_SCHPO Septation protein imp2 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=imp2 PE=1
SV=1
Length=670
Score = 49.7 bits (117), Expect = 7e-05, Method: Composition-based stats.
Identities = 17/66 (26%), Positives = 32/66 (48%), Gaps = 9/66 (14%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+V A +DYD + + SF+KGD + V+ + WW+ + G++D+ G P
Sbjct 611 YVSALYDYDAAIPEEI-------SFRKGDTIAVLKLYEDGWWEGFVVGEDDHN--RGQFP 661
Query 409 GKSFQQ 414
++
Sbjct 662 SNFVRE 667
>sp|P53671|LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapiens OX=9606
GN=LIMK2 PE=1 SV=1
Length=638
Score = 49.7 bits (117), Expect = 8e-05, Method: Composition-based stats.
Identities = 23/107 (21%), Positives = 47/107 (44%), Gaps = 9/107 (8%)
Query 234 LEPITDERVYESIGQYGGETVKIVRI------EKARDIPLGATVRNEMDSVIISRI--VK 285
L P+ + ES+ + +V ++ + + + + + N +V + + +
Sbjct 130 LAPMFERLSTESVQEQLPYSVTLISMPATTEGRRGFSVSVESACSNYATTVQVKEVNRMH 189
Query 286 GGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
++ +H GD +LEING +R V EV D +S TL ++
Sbjct 190 ISPNNRN-AIHPGDRILEINGTPVRTLRVEEVEDAISQTSQTLQLLI 235
>sp|Q6DKE2|DVL3_XENLA Segment polarity protein dishevelled homolog
DVL-3 OS=Xenopus laevis OX=8355 GN=dvl3 PE=2 SV=1
Length=717
Score = 49.7 bits (117), Expect = 8e-05, Method: Composition-based stats.
Identities = 16/69 (23%), Positives = 29/69 (42%), Gaps = 3/69 (4%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD--- 323
+G + + I I+KGGA G + GD +L++N ++ +L D
Sbjct 264 VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDTNFENMSNDDAVRVLRDIVH 323
Query 324 MHGTLTFVL 332
G +T +
Sbjct 324 KPGPITLTV 332
>sp|Q76G19|PDZD4_HUMAN PDZ domain-containing protein 4 OS=Homo
sapiens OX=9606 GN=PDZD4 PE=1 SV=1
Length=769
Score = 49.7 bits (117), Expect = 8e-05, Method: Composition-based stats.
Identities = 33/199 (17%), Positives = 70/199 (35%), Gaps = 8/199 (4%)
Query 150 LLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELT 209
L +L Q + Q + + + + SP S+ DL + + L
Sbjct 26 LSKLSQEQTLQALRSSKEPLVIQVLRRSPRLRGDSSCHDLQLVDSGTQTDITFEHIMALG 85
Query 210 ALLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGA 269
L P ++L ++ + + E+ E ++ + + LG
Sbjct 86 K-LRPPTPPMVILEPPPISHEYYDPAEFMEGGPQEADRLDELEYEEVELYKSSHRDKLGL 144
Query 270 -----TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
T E + + + A K G + EGD +++ING++++ + E +LS
Sbjct 145 MVCYRTDDEEDLGIYVGEVNPNSIAAKDGRIREGDRIIQINGVDVQNR--EEAVAILSQE 202
Query 325 HGTLTFVLIPSQQIKPPPA 343
T +L+ + +
Sbjct 203 ENTNISLLVARPESQLAKR 221
>sp|B1WAP7|DVL3_XENTR Segment polarity protein dishevelled homolog
DVL-3 OS=Xenopus tropicalis OX=8364 GN=dvl3 PE=2 SV=1
Length=713
Score = 49.7 bits (117), Expect = 8e-05, Method: Composition-based stats.
Identities = 15/69 (22%), Positives = 29/69 (42%), Gaps = 3/69 (4%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD--- 323
+G + + I I+KGGA G + GD +L++N ++ +L +
Sbjct 264 VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDTNFENMSNDDAVRVLREIVH 323
Query 324 MHGTLTFVL 332
G +T +
Sbjct 324 KPGPITLTV 332
>sp|P46109|CRKL_HUMAN Crk-like protein OS=Homo sapiens OX=9606
GN=CRKL PE=1 SV=1
Length=303
Score = 48.9 bits (115), Expect = 8e-05, Method: Composition-based stats.
Identities = 18/75 (24%), Positives = 36/75 (48%), Gaps = 12/75 (16%)
Query 340 PPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDED 399
P A++ + +V+ +D+ P +D L F+KG+IL +I + + WW A +
Sbjct 118 LPTAEDNLEYVRTLYDF-PGNDAED------LPFKKGEILVIIEKPEEQWWSAR-----N 165
Query 400 NQPLAGLVPGKSFQQ 414
G++P ++
Sbjct 166 KDGRVGMIPVPYVEK 180
>sp|P53668|LIMK1_MOUSE LIM domain kinase 1 OS=Mus musculus OX=10090
GN=Limk1 PE=1 SV=1
Length=647
Score = 49.7 bits (117), Expect = 8e-05, Method: Composition-based stats.
Identities = 27/129 (21%), Positives = 52/129 (40%), Gaps = 15/129 (12%)
Query 234 LEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNE------------MDSVIIS 281
+ P+ ++ + +S G + TV +V I + G +V + +V +
Sbjct 143 VTPVIEQILPDSPGSHLPHTVTLVSIPASAHGKRGLSVSIDPPHGPPGCGTEHSHTVRVQ 202
Query 282 RIVKGGAA-EKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI--PSQQI 338
+ G + + +H GD +LEING IR ++E+ L+ + L L P +
Sbjct 203 GVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEIDLLIQETSRLLQLTLEHDPHDSL 262
Query 339 KPPPAKETV 347
P +
Sbjct 263 GHGPVSDPS 271
>sp|P38753|HSE1_YEAST Class E vacuolar protein-sorting machinery
protein HSE1 OS=Saccharomyces cerevisiae (strain ATCC 204508
/ S288c) OX=559292 GN=HSE1 PE=1 SV=1
Length=452
Score = 49.3 bits (116), Expect = 9e-05, Method: Composition-based stats.
Identities = 20/67 (30%), Positives = 33/67 (49%), Gaps = 7/67 (10%)
Query 342 PAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQ 401
PA+ V V+A +D ++ LSF+KGD++ V+ Q +WW+ G+
Sbjct 214 PAQTVVRRVRALYDLTTNEPDE-------LSFRKGDVITVLEQVYRDWWKGALRGNMGIF 266
Query 402 PLAGLVP 408
PL + P
Sbjct 267 PLNYVTP 273
>sp|O54785|LIMK2_MOUSE LIM domain kinase 2 OS=Mus musculus OX=10090
GN=Limk2 PE=1 SV=2
Length=638
Score = 49.7 bits (117), Expect = 9e-05, Method: Composition-based stats.
Identities = 25/127 (20%), Positives = 52/127 (41%), Gaps = 13/127 (10%)
Query 234 LEPITDERVYESIGQYGGETVKIVRI------EKARDIPLGATVRNEMDSVIISRI--VK 285
L P+ + ES+ +V ++ + + + + + N +V + + +
Sbjct 130 LAPMFERLSTESVQDQLPYSVTLISMPATTECRRGFSVTVESASSNYATTVQVKEVNRMH 189
Query 286 GGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKE 345
++ +H GD +LEING +R V EV D + TL ++ + P P +
Sbjct 190 ISPNNRN-AIHPGDRILEINGTPVRTLRVEEVEDAIKQTSQTLQLLI----EHDPVPQRL 244
Query 346 TVIHVKA 352
+ + A
Sbjct 245 DQLRLDA 251
>sp|Q22227|MIG5_CAEEL Segment polarity protein dishevelled homolog
mig-5 OS=Caenorhabditis elegans OX=6239 GN=mig-5 PE=1 SV=1
Length=672
Score = 49.7 bits (117), Expect = 9e-05, Method: Composition-based stats.
Identities = 15/61 (25%), Positives = 28/61 (46%), Gaps = 0/61 (0%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
LG +V + +S I GA EK G ++ GD++L++N + + L +
Sbjct 237 LGLSVCTIDGHIFVSEIAPEGAVEKDGRVNVGDQILQVNRVSFEELSGPQAVRSLREAAS 296
Query 327 T 327
+
Sbjct 297 S 297
>sp|P10936|YES_XENLA Tyrosine-protein kinase Yes OS=Xenopus laevis
OX=8355 GN=yes1 PE=2 SV=3
Length=537
Score = 49.3 bits (116), Expect = 9e-05, Method: Composition-based stats.
Identities = 18/88 (20%), Positives = 31/88 (35%), Gaps = 11/88 (13%)
Query 326 GTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE 385
G + + P+ P V A +DY+ LSF+KG+ +I+
Sbjct 66 GGASSIFSPTPVPYPGGLTGGVTVFVALYDYEARTTED-------LSFRKGERFQIINNT 118
Query 386 DPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
+ +WW+A G +P
Sbjct 119 EGDWWEARSI----ATGKTGYIPSNYVA 142
>sp|Q4P5J4|HSE1_USTMA Class E vacuolar protein-sorting machinery
protein HSE1 OS=Ustilago maydis (strain 521 / FGSC 9021)
OX=237631 GN=HSE1 PE=3 SV=1
Length=593
Score = 49.3 bits (116), Expect = 1e-04, Method: Composition-based stats.
Identities = 25/143 (17%), Positives = 56/143 (39%), Gaps = 16/143 (11%)
Query 333 IPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 392
P PP V+A +D+ P++ L+F +G+++ V+ +WW+
Sbjct 243 QPLSAATPPAVASR---VRALYDFSPTEPGE-------LAFSRGEVIRVLDSVYEHWWRG 292
Query 393 YREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNA 452
G AG+ P + + ++ + + E A ++ K +
Sbjct 293 EVRG------EAGIFPVNYVEVLPDPTPDELQREAQMEARIFSQAADIDRLLSKLRSLDP 346
Query 453 NKNDDYDNEEILTYEEMSLYHQP 475
+++ D++E+ + SL +P
Sbjct 347 ARDNLADDDELQELYQKSLAMRP 369
>sp|F1LM93|YES_RAT Tyrosine-protein kinase Yes OS=Rattus norvegicus
OX=10116 GN=Yes1 PE=1 SV=1
Length=541
Score = 49.3 bits (116), Expect = 1e-04, Method: Composition-based stats.
Identities = 16/67 (24%), Positives = 26/67 (39%), Gaps = 12/67 (18%)
Query 347 VIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGL 406
I V A +DY+ LSF+KG+ +I+ + +WW+A G
Sbjct 92 TIFV-ALYDYEARTTED-------LSFKKGERFQIINNTEGDWWEARSI----ATGKNGY 139
Query 407 VPGKSFQ 413
+P
Sbjct 140 IPSNYVA 146
>sp|Q04736|YES_MOUSE Tyrosine-protein kinase Yes OS=Mus musculus
OX=10090 GN=Yes1 PE=1 SV=3
Length=541
Score = 49.3 bits (116), Expect = 1e-04, Method: Composition-based stats.
Identities = 16/67 (24%), Positives = 27/67 (40%), Gaps = 12/67 (18%)
Query 347 VIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGL 406
I V A +DY+ LSF+KG+ +I+ + +WW+A +G
Sbjct 92 TIFV-ALYDYEARTTED-------LSFKKGERFQIINNTEGDWWEARSI----ATGKSGY 139
Query 407 VPGKSFQ 413
+P
Sbjct 140 IPSNYVV 146
>sp|P07947|YES_HUMAN Tyrosine-protein kinase Yes OS=Homo sapiens
OX=9606 GN=YES1 PE=1 SV=3
Length=543
Score = 49.3 bits (116), Expect = 1e-04, Method: Composition-based stats.
Identities = 16/67 (24%), Positives = 26/67 (39%), Gaps = 12/67 (18%)
Query 347 VIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGL 406
I V A +DY+ LSF+KG+ +I+ + +WW+A G
Sbjct 94 TIFV-ALYDYEARTTED-------LSFKKGERFQIINNTEGDWWEARSI----ATGKNGY 141
Query 407 VPGKSFQ 413
+P
Sbjct 142 IPSNYVA 148
>sp|P63185|SRC_RSVSE Tyrosine-protein kinase transforming protein
Src OS=Rous sarcoma virus subgroup E (strain Schmidt-Ruppin)
OX=270623 GN=V-SRC PE=1 SV=3
Length=526
Score = 49.3 bits (116), Expect = 1e-04, Method: Composition-based stats.
Identities = 16/62 (26%), Positives = 26/62 (42%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ E LSF+KG+ L +++ + NWW A+ G +P
Sbjct 88 ALYDYE-------SWIETDLSFKKGERLQIVNNTEGNWWLAHSVT----TGQTGYIPSNY 136
Query 412 FQ 413
Sbjct 137 VA 138
>sp|Q9EQZ7|RIMS2_MOUSE Regulating synaptic membrane exocytosis
protein 2 OS=Mus musculus OX=10090 GN=Rims2 PE=1 SV=1
Length=1530
Score = 49.7 bits (117), Expect = 1e-04, Method: Composition-based stats.
Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 0/65 (0%)
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
I+++ KG A+ G L GDEVLE NG ++G EV++++ + L+ S+ I
Sbjct 706 FITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPI 765
Query 339 KPPPA 343
P
Sbjct 766 GDIPR 770
>sp|Q9UQ26|RIMS2_HUMAN Regulating synaptic membrane exocytosis
protein 2 OS=Homo sapiens OX=9606 GN=RIMS2 PE=1 SV=2
Length=1411
Score = 49.3 bits (116), Expect = 1e-04, Method: Composition-based stats.
Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 0/65 (0%)
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
I+++ KG A+ G L GDEVLE NG ++G EV++++ + L+ S+ I
Sbjct 697 FITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPI 756
Query 339 KPPPA 343
P
Sbjct 757 GDIPR 761
>sp|Q9JIS1|RIMS2_RAT Regulating synaptic membrane exocytosis protein
2 OS=Rattus norvegicus OX=10116 GN=Rims2 PE=1 SV=1
Length=1555
Score = 49.3 bits (116), Expect = 1e-04, Method: Composition-based stats.
Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 0/65 (0%)
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
I+++ KG A+ G L GDEVLE NG ++G EV++++ + L+ S+ I
Sbjct 619 FITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNIILESKPEPQVELVVSRPI 678
Query 339 KPPPA 343
P
Sbjct 679 GDMPR 683
>sp|P00525|SRC_AVISR Tyrosine-protein kinase transforming protein
Src OS=Avian sarcoma virus (strain rASV1441) OX=11894 GN=V-SRC
PE=1 SV=3
Length=526
Score = 48.9 bits (115), Expect = 1e-04, Method: Composition-based stats.
Identities = 15/62 (24%), Positives = 26/62 (42%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ E LSF+KG+ L +++ + +WW A+ G +P
Sbjct 88 ALYDYESR-------TETDLSFKKGERLQIVNNTEGDWWLAH----SLTTGQTGYIPSNY 136
Query 412 FQ 413
Sbjct 137 VA 138
>sp|P00523|SRC_CHICK Proto-oncogene tyrosine-protein kinase Src
OS=Gallus gallus OX=9031 GN=SRC PE=1 SV=4
Length=533
Score = 48.9 bits (115), Expect = 1e-04, Method: Composition-based stats.
Identities = 15/62 (24%), Positives = 26/62 (42%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ E LSF+KG+ L +++ + +WW A+ G +P
Sbjct 88 ALYDYESR-------TETDLSFKKGERLQIVNNTEGDWWLAH----SLTTGQTGYIPSNY 136
Query 412 FQ 413
Sbjct 137 VA 138
>sp|E1JIT7|PSD_DROME PH and SEC7 domain-containing protein OS=Drosophila
melanogaster OX=7227 GN=Efa6 PE=1 SV=2
Length=1601
Score = 49.3 bits (116), Expect = 1e-04, Method: Composition-based stats.
Identities = 20/89 (22%), Positives = 36/89 (40%), Gaps = 1/89 (1%)
Query 252 ETVKIVRIEKARDIPLGATV-RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIR 310
E +K+V + G ++ +I IV+ A G + GD +L++NG ++
Sbjct 3 EELKVVLRRSEQHSGFGFSLLGTTGPPHVIYDIVENSPAADCGAVEAGDVILKVNGTDVH 62
Query 311 GKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
EV L +T L ++K
Sbjct 63 RYTTKEVLKCLRLSEQLVTLELKRDPKLK 91
>sp|Q4P9Q7|SHO1_USTMA High osmolarity signaling protein SHO1 OS=Ustilago
maydis (strain 521 / FGSC 9021) OX=237631 GN=SHO1
PE=3 SV=1
Length=335
Score = 48.5 bits (114), Expect = 1e-04, Method: Composition-based stats.
Identities = 17/63 (27%), Positives = 27/63 (43%), Gaps = 11/63 (17%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
+A + Y + D +SF KG++L ++ WWQA R + G+VP
Sbjct 282 RALYAYQANADD-----PTEISFSKGEVLDIVDNSGK-WWQARR-----SNGETGIVPSN 330
Query 411 SFQ 413
Q
Sbjct 331 YMQ 333
>sp|P14084|SRC_AVISS Tyrosine-protein kinase transforming protein
Src OS=Avian sarcoma virus (strain S1) OX=11881 GN=V-SRC
PE=3 SV=3
Length=568
Score = 48.9 bits (115), Expect = 1e-04, Method: Composition-based stats.
Identities = 15/62 (24%), Positives = 26/62 (42%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ E LSF+KG+ L +++ + +WW A+ G +P
Sbjct 88 ALYDYESR-------TETDLSFKKGERLQIVNNTEGDWWLAH----SLTTGQTGYIPSNY 136
Query 412 FQ 413
Sbjct 137 VA 138
>sp|Q9Z0R6|ITSN2_MOUSE Intersectin-2 OS=Mus musculus OX=10090
GN=Itsn2 PE=1 SV=2
Length=1659
Score = 49.3 bits (116), Expect = 1e-04, Method: Composition-based stats.
Identities = 23/83 (28%), Positives = 36/83 (43%), Gaps = 13/83 (16%)
Query 330 FVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNW 389
L+ + P V V A +DY + E L+F KG +++V++++DP+W
Sbjct 1073 VKLLGPSSERTMPTFHAVCQVIAMYDY-------MANNEDELNFSKGQLINVMNKDDPDW 1125
Query 390 WQAYREGDEDNQPLAGLVPGKSF 412
WQ G L GL P
Sbjct 1126 WQGETNG------LTGLFPSNYV 1142
>sp|P15054|SRC_AVIS2 Tyrosine-protein kinase transforming protein
Src OS=Avian sarcoma virus (strain PR2257) OX=11879 GN=V-SRC
PE=3 SV=3
Length=587
Score = 48.9 bits (115), Expect = 1e-04, Method: Composition-based stats.
Identities = 15/62 (24%), Positives = 26/62 (42%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ E LSF+KG+ L +++ + +WW A+ G +P
Sbjct 88 ALYDYESR-------TETDLSFKKGERLQIVNNTEGDWWLAH----SLTTGQTGYIPSNY 136
Query 412 FQ 413
Sbjct 137 VA 138
>sp|Q92614|MY18A_HUMAN Unconventional myosin-XVIIIa OS=Homo sapiens
OX=9606 GN=MYO18A PE=1 SV=3
Length=2054
Score = 49.3 bits (116), Expect = 1e-04, Method: Composition-based stats.
Identities = 12/68 (18%), Positives = 29/68 (43%), Gaps = 1/68 (1%)
Query 279 IISRIVKG-GAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
++ G G + + L GD ++EING + K +E+ +++ ++ + P +
Sbjct 253 VVHFAEPGAGTKDLALGLVPGDRLVEINGHNVESKSRDEIVEMIRQSGDSVRLKVQPIPE 312
Query 338 IKPPPAKE 345
+
Sbjct 313 LSELSRSW 320
>sp|P14234|FGR_MOUSE Tyrosine-protein kinase Fgr OS=Mus musculus
OX=10090 GN=Fgr PE=1 SV=2
Length=517
Score = 48.9 bits (115), Expect = 1e-04, Method: Composition-based stats.
Identities = 19/112 (17%), Positives = 34/112 (30%), Gaps = 17/112 (15%)
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVK------AHFDYDPSDD 361
+ R + E + T + P+ I A +DY+
Sbjct 22 DFRSQTAEERYFPDPTQGRTSSVFPQPTSPAFLNTGNMRSISGTGVTIFVALYDYEARTG 81
Query 362 PYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
L+F KG+ H+++ + +WW+A G VP
Sbjct 82 DD-------LTFTKGEKFHILNNTEYDWWEARSLSSGH----RGYVPSNYVA 122
>sp|P27446|FYN_XIPHE Tyrosine-protein kinase Fyn OS=Xiphophorus
hellerii OX=8084 GN=fyn PE=2 SV=3
Length=537
Score = 48.9 bits (115), Expect = 1e-04, Method: Composition-based stats.
Identities = 13/62 (21%), Positives = 25/62 (40%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ + LSF+KG+ +++ + +WW A + G +P
Sbjct 89 ALYDYEARTEDD-------LSFRKGERFQILNSTEGDWWDARSLTTGGS----GYIPSNY 137
Query 412 FQ 413
Sbjct 138 VA 139
>sp|P14085|SRC_AVIST Tyrosine-protein kinase transforming protein
Src OS=Avian sarcoma virus (strain S2) OX=11882 GN=V-SRC
PE=3 SV=3
Length=557
Score = 48.9 bits (115), Expect = 1e-04, Method: Composition-based stats.
Identities = 15/62 (24%), Positives = 26/62 (42%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ E LSF+KG+ L +++ + +WW A+ G +P
Sbjct 88 ALYDYESR-------TETDLSFKKGERLQIVNNTEGDWWLAH----SLTTGQTGYIPSNY 136
Query 412 FQ 413
Sbjct 137 VA 138
>sp|Q9XYM0|CRK_DROME Adapter molecule Crk OS=Drosophila melanogaster
OX=7227 GN=Crk PE=1 SV=1
Length=271
Score = 47.7 bits (112), Expect = 1e-04, Method: Composition-based stats.
Identities = 32/137 (23%), Positives = 53/137 (39%), Gaps = 17/137 (12%)
Query 329 TFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPN 388
T + + +K P + V V FD+ SD +P FQ+G++L ++ +++
Sbjct 91 TLHYLDTTPLKRPACR-RVEKVIGKFDFVGSDQDDLP-------FQRGEVLTIVRKDEDQ 142
Query 389 WWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKL----WCAKKNKKK 444
WW A ++ G +P QQ + M + + EP SG K+
Sbjct 143 WWTAR-----NSSGKIGQIPVPYIQQYDDYMDEDAIDKNEPSISGSSNVFESTLKRTDLN 197
Query 445 RKKVLYNANKNDDYDNE 461
RK Y K N
Sbjct 198 RKLPAYARVKQSRVPNA 214
>sp|Q9PU47|PDLI3_CHICK PDZ and LIM domain protein 3 OS=Gallus
gallus OX=9031 GN=PDLIM3 PE=1 SV=1
Length=315
Score = 48.1 bits (113), Expect = 1e-04, Method: Composition-based stats.
Identities = 24/157 (15%), Positives = 46/157 (29%), Gaps = 14/157 (9%)
Query 266 PLGATVRNEM-DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
+ + +II+RI G A + L GD ++ ING+ N+ + +
Sbjct 14 GFRLSGGIDFNQPLIITRITPGSKA-STANLCPGDIIVAINGLSTENMTHNDAQERIKAA 72
Query 325 HGTLTFVLIPSQQIKPPP-----AKETVIHVKAHFDYDPSDDPYVPCRELGLSF----QK 375
L+ + ++ P K + + F
Sbjct 73 AHQLSLRIERAETKLWSPQVSEDGKANPYKINLEAEPQEFKPIGTAHNRRAQPFVAAANI 132
Query 376 GDILHVISQEDP---NWWQAYREGDEDNQPLAGLVPG 409
D V+S + + D + L L+P
Sbjct 133 DDKRQVVSSSYNSPIGLYSSGNIQDALHGQLRSLIPN 169
>sp|P28191|PTP1_CAEEL Tyrosine-protein phosphatase 1 OS=Caenorhabditis
elegans OX=6239 GN=ptp-1 PE=2 SV=3
Length=1026
Score = 49.3 bits (116), Expect = 1e-04, Method: Composition-based stats.
Identities = 26/101 (26%), Positives = 45/101 (45%), Gaps = 9/101 (9%)
Query 244 ESIGQYGGETVKIVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEK-SGLLHEGD 299
+S G + V +++ R G V+ D VI+SR+ G +A+K L+EGD
Sbjct 605 KSSSPVGEDQVVTIKMRPDRHGRFGFNVKGGADQNYPVIVSRVAPGSSADKCQPRLNEGD 664
Query 300 EVLEINGIEIRGKDVNEVFDLLSDM-----HGTLTFVLIPS 335
+VL I+G ++ + V + G L + P+
Sbjct 665 QVLFIDGRDVSTMSHDHVVQFIRSARSGLNGGELHLTIRPN 705
>sp|Q75DS3|HSE1_EREGS Class E vacuolar protein-sorting machinery
protein HSE1 OS=Eremothecium gossypii (strain ATCC 10895
/ CBS 109.51 / FGSC 9923 / NRRL Y-1056) OX=284811 GN=HSE1 PE=3
SV=1
Length=443
Score = 48.5 bits (114), Expect = 1e-04, Method: Composition-based stats.
Identities = 24/85 (28%), Positives = 38/85 (45%), Gaps = 9/85 (11%)
Query 332 LIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQ 391
L + P + V VKA FD + S+ LSF+KGD++ VI Q +WW+
Sbjct 197 LASETSLPEQPQPQIVRRVKAIFDLNASEPDE-------LSFKKGDVITVIEQVYKDWWR 249
Query 392 AYREGDEDNQPLA--GLVPGKSFQQ 414
G P+ G+ P + ++
Sbjct 250 GLLRGKVGIFPVNYVGVCPEPTAEE 274
>sp|Q99JZ0|SDCB2_MOUSE Syntenin-2 OS=Mus musculus OX=10090 GN=Sdcbp2
PE=2 SV=1
Length=292
Score = 47.7 bits (112), Expect = 2e-04, Method: Composition-based stats.
Identities = 33/213 (15%), Positives = 70/213 (33%), Gaps = 23/213 (11%)
Query 175 KASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDK-----VAE 229
+ASP P + A + + + E +L + + L D +
Sbjct 22 RASPTMPTLPAPMASAPPLSELYPNLAELESYMGLSLSSQEVQKNLTQIPDSDNMVVTSP 81
Query 230 QEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAA 289
Q+ + V+ + + K G ++ + + + A
Sbjct 82 GPGQVVAPVSGNNLGILRAEIKPGVREIHLCKDERGKTGLRLQAVDKGLFVQLVQANTPA 141
Query 290 EKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIH 349
G L GD++L+I+G + G + ++ +L ++I + +
Sbjct 142 SLVG-LRFGDQILQIDGCDCAGWNTHKAHKVLKKASAEKIVMVIRDRPFQRT-------- 192
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVI 382
V H D ++G S +KG I+ V+
Sbjct 193 VTMHKD---------SSGQVGFSIKKGKIVSVV 216
Score = 47.4 bits (111), Expect = 2e-04, Method: Composition-based stats.
Identities = 21/80 (26%), Positives = 39/80 (49%), Gaps = 5/80 (6%)
Query 255 KIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
+ V + K +G +++ I +VKG +A ++GLL V E+NG + G
Sbjct 191 RTVTMHKDSSGQVGFSIKKGK----IVSVVKGSSAARNGLL-TNHYVCEVNGQNVIGLKD 245
Query 315 NEVFDLLSDMHGTLTFVLIP 334
+V ++L+ +T +IP
Sbjct 246 KKVTEILTTAGDVITLTIIP 265
>sp|P00524|SRC_RSVSA Tyrosine-protein kinase transforming protein
Src OS=Rous sarcoma virus subgroup A (strain Schmidt-Ruppin)
OX=269446 GN=V-SRC PE=1 SV=6
Length=526
Score = 48.5 bits (114), Expect = 2e-04, Method: Composition-based stats.
Identities = 16/62 (26%), Positives = 26/62 (42%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ E LSF+KG+ L +++ + NWW A+ G +P
Sbjct 88 ALYDYE-------SWIETDLSFKKGERLQIVNNTEGNWWLAH----SLTTGQTGYIPSNY 136
Query 412 FQ 413
Sbjct 137 VA 138
>sp|Q61085|RHPN1_MOUSE Rhophilin-1 OS=Mus musculus OX=10090 GN=Rhpn1
PE=1 SV=2
Length=643
Score = 48.5 bits (114), Expect = 2e-04, Method: Composition-based stats.
Identities = 26/118 (22%), Positives = 44/118 (37%), Gaps = 7/118 (6%)
Query 227 VAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKG 286
+ + Q V + R E + G T+R + V+I+ +V G
Sbjct 474 IQPKTHQTPEGPLSVFSTKNRWQLVGPVHMTRGEGS----FGFTLRGD-SPVLIAAVVPG 528
Query 287 GAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMH-GTLTFVLIPSQQIKPPPA 343
G AE +G L EGD ++ +NG + EV L M ++ ++ P
Sbjct 529 GQAESAG-LKEGDYIVSVNGQPCKWWKHLEVVTQLRSMGEEGVSLQVVSLLPSPEPRG 585
>sp|P26045|PTN3_HUMAN Tyrosine-protein phosphatase non-receptor
type 3 OS=Homo sapiens OX=9606 GN=PTPN3 PE=1 SV=2
Length=913
Score = 48.9 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 18/76 (24%), Positives = 36/76 (47%), Gaps = 4/76 (5%)
Query 256 IVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEKS-GLLHEGDEVLEINGIEIRG 311
++RI D G ++ +D +++SRI A+ L+EGD+++ ING +I
Sbjct 510 LIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISE 569
Query 312 KDVNEVFDLLSDMHGT 327
++V + +
Sbjct 570 HTHDQVVMFIKASRES 585
>sp|O42287|ITSN1_XENLA Intersectin-1 OS=Xenopus laevis OX=8355
GN=itsn1 PE=1 SV=2
Length=1705
Score = 48.9 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 25/95 (26%), Positives = 37/95 (39%), Gaps = 18/95 (19%)
Query 318 FDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGD 377
LLS T P PP + V +DY +D L+F KG
Sbjct 1117 VKLLSPGTNKSTPTEPPKPTSLPPTCQ-----VIGMYDYIAQNDDE-------LAFSKGQ 1164
Query 378 ILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSF 412
+++V+++EDP+WW+ G GL P
Sbjct 1165 VINVLNKEDPDWWKGELNG------HVGLFPSNYV 1193
>sp|P47941|CRKL_MOUSE Crk-like protein OS=Mus musculus OX=10090
GN=Crkl PE=1 SV=2
Length=303
Score = 47.7 bits (112), Expect = 2e-04, Method: Composition-based stats.
Identities = 18/75 (24%), Positives = 36/75 (48%), Gaps = 12/75 (16%)
Query 340 PPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDED 399
P A+E + +V+ +D+ P +D L F+KG++L +I + + WW A +
Sbjct 118 LPTAEENLEYVRTLYDF-PGNDAED------LPFKKGELLVIIEKPEEQWWSAR-----N 165
Query 400 NQPLAGLVPGKSFQQ 414
G++P ++
Sbjct 166 KDGRVGMIPVPYVEK 180
>sp|Q6P9H4|CNKR3_HUMAN Connector enhancer of kinase suppressor
of ras 3 OS=Homo sapiens OX=9606 GN=CNKSR3 PE=1 SV=1
Length=555
Score = 48.5 bits (114), Expect = 2e-04, Method: Composition-based stats.
Identities = 15/71 (21%), Positives = 34/71 (48%), Gaps = 1/71 (1%)
Query 264 DIPLGATVRNEMDSV-IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
LG +++ D + +I+ + A++S +H GDEV+++N + G + + L
Sbjct 220 GEGLGMYIKSTYDGLHVITGTTENSPADRSQKIHAGDEVIQVNQQTVVGWQLKNLVKKLR 279
Query 323 DMHGTLTFVLI 333
+ + +L
Sbjct 280 ENPTGVVLLLK 290
>sp|Q8TCX5|RHPN1_HUMAN Rhophilin-1 OS=Homo sapiens OX=9606 GN=RHPN1
PE=1 SV=2
Length=670
Score = 48.5 bits (114), Expect = 2e-04, Method: Composition-based stats.
Identities = 22/89 (25%), Positives = 38/89 (43%), Gaps = 6/89 (7%)
Query 264 DIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD 323
+ G T+R + V+I+ ++ G A +G L EGD ++ +NG R EV L
Sbjct 520 EGGFGLTLRGD-SPVLIAAVIPGSQAAAAG-LKEGDYIVSVNGQPCRWWRHAEVVTELKA 577
Query 324 MHGT----LTFVLIPSQQIKPPPAKETVI 348
L+PS ++ + V+
Sbjct 578 AGEAGASLQVVSLLPSSRLPSLGDRRPVL 606
>sp|P00526|SRC_RSVP Tyrosine-protein kinase transforming protein
Src OS=Rous sarcoma virus subgroup C (strain Prague) OX=11888
GN=V-SRC PE=1 SV=3
Length=526
Score = 48.1 bits (113), Expect = 2e-04, Method: Composition-based stats.
Identities = 23/122 (19%), Positives = 48/122 (39%), Gaps = 25/122 (20%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ E LSF+KG+ L +++ + +WW A+ G +P
Sbjct 88 ALYDYE-------SWTETDLSFKKGERLQIVNNTEGDWWLAH----SLTTGQTGYIPSNY 136
Query 412 F--------QQQ---REAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDN 460
++ + +++ PE + +K+ + K Y + +D +DN
Sbjct 137 VAPSDSIQAEEWYFGKITRRESERLLLNPENPRGTFLVRKS--ETAKGAYCLSVSD-FDN 193
Query 461 EE 462
+
Sbjct 194 AK 195
>sp|P00527|YES_AVISY Tyrosine-protein kinase transforming protein
Yes (Fragment) OS=Y73 avian sarcoma virus OX=11884 GN=V-YES
PE=3 SV=2
Length=528
Score = 48.1 bits (113), Expect = 2e-04, Method: Composition-based stats.
Identities = 18/89 (20%), Positives = 31/89 (35%), Gaps = 13/89 (15%)
Query 325 HGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ 384
+ +F +PS TV A +DY+ LSF+ G+ +I+
Sbjct 63 GASSSFSAVPSPYPSTLTGGGTVFV--ALYDYEARTTDD-------LSFKGGERFQIINN 113
Query 385 EDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
+ +WW+A G +P
Sbjct 114 TEGDWWEARSI----ATGKTGYIPSNYVA 138
>sp|O35002|CTPB_BACSU Carboxy-terminal processing protease CtpB
OS=Bacillus subtilis (strain 168) OX=224308 GN=ctpB PE=1 SV=1
Length=480
Score = 48.1 bits (113), Expect = 2e-04, Method: Composition-based stats.
Identities = 25/88 (28%), Positives = 40/88 (45%), Gaps = 7/88 (8%)
Query 265 IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
+GA V E +II K AEK+G L DE++ ING + GKD+N +
Sbjct 112 EGIGAEVGMEDGKIIIVSPFKKSPAEKAG-LKPNDEIISINGESMAGKDLNHAVLKIRGK 170
Query 325 HG-TLTFVLIPSQQIKPPPAKETVIHVK 351
G +++ + +P K+ +K
Sbjct 171 KGSSVSMKIQ-----RPGTKKQLSFRIK 193
>sp|O34666|CTPA_BACSU Carboxy-terminal processing protease CtpA
OS=Bacillus subtilis (strain 168) OX=224308 GN=ctpA PE=2 SV=1
Length=466
Score = 48.1 bits (113), Expect = 2e-04, Method: Composition-based stats.
Identities = 20/63 (32%), Positives = 36/63 (57%), Gaps = 1/63 (2%)
Query 265 IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
+GA V + ++I +KG AEK+G + D+++++NG ++G +VNE L+
Sbjct 104 EGIGAQVEEKDGEILIVSPIKGSPAEKAG-IKPRDQIIKVNGKSVKGMNVNEAVALIRGK 162
Query 325 HGT 327
GT
Sbjct 163 KGT 165
>sp|E7A253|SHO1_SPORE High osmolarity signaling protein SHO1 OS=Sporisorium
reilianum (strain SRZ2) OX=999809 GN=SHO1 PE=3
SV=1
Length=343
Score = 47.7 bits (112), Expect = 2e-04, Method: Composition-based stats.
Identities = 16/63 (25%), Positives = 27/63 (43%), Gaps = 11/63 (17%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
+A + Y + D +SF KG++L ++ WWQA + + G+VP
Sbjct 290 RALYAYQANADD-----PTEISFSKGEVLDIVDNSGK-WWQARK-----SNGETGIVPSN 338
Query 411 SFQ 413
Q
Sbjct 339 YMQ 341
>sp|F1PBJ0|RPGF2_CANLF Rap guanine nucleotide exchange factor
2 OS=Canis lupus familiaris OX=9615 GN=RAPGEF2 PE=1 SV=2
Length=1498
Score = 48.5 bits (114), Expect = 2e-04, Method: Composition-based stats.
Identities = 16/83 (19%), Positives = 39/83 (47%), Gaps = 6/83 (7%)
Query 254 VKIVRIEK-ARDIPLGA---TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+++ + K +R+ PL + + + + G A ++G L GD++LE+NG
Sbjct 383 RRLMTLTKPSREAPLPFILLGGSEKGFGIFVDSVDSGSKATEAG-LKRGDQILEVNGQNF 441
Query 310 RGKDVNEVFDLLSDMHG-TLTFV 331
+++ ++L + ++T
Sbjct 442 ENIQLSKAMEILRNNTHLSITVK 464
>sp|Q15811|ITSN1_HUMAN Intersectin-1 OS=Homo sapiens OX=9606 GN=ITSN1
PE=1 SV=3
Length=1721
Score = 48.5 bits (114), Expect = 2e-04, Method: Composition-based stats.
Identities = 24/84 (29%), Positives = 37/84 (44%), Gaps = 14/84 (17%)
Query 329 TFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPN 388
T + P++ K A V V +DY +D L+F KG I++V+++EDP+
Sbjct 1140 TSKITPTEPPK-STALAAVCQVIGMYDYTAQNDDE-------LAFNKGQIINVLNKEDPD 1191
Query 389 WWQAYREGDEDNQPLAGLVPGKSF 412
WW+ G GL P
Sbjct 1192 WWKGEVNG------QVGLFPSNYV 1209
>sp|Q5SGD7|CNKR3_RAT Connector enhancer of kinase suppressor of
ras 3 OS=Rattus norvegicus OX=10116 GN=Cnksr3 PE=1 SV=1
Length=555
Score = 48.1 bits (113), Expect = 2e-04, Method: Composition-based stats.
Identities = 15/71 (21%), Positives = 34/71 (48%), Gaps = 1/71 (1%)
Query 264 DIPLGATVRNEMDSV-IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
LG +++ D + +I+ + A++S +H GDEV+++N + G + + L
Sbjct 220 GEGLGMYIKSTYDGLHVITGTTENSPADRSQKIHAGDEVIQVNRQTVVGWQLKNLVKKLR 279
Query 323 DMHGTLTFVLI 333
+ + +L
Sbjct 280 ENPTGVVLLLK 290
>sp|Q9Y4G8|RPGF2_HUMAN Rap guanine nucleotide exchange factor
2 OS=Homo sapiens OX=9606 GN=RAPGEF2 PE=1 SV=1
Length=1499
Score = 48.5 bits (114), Expect = 2e-04, Method: Composition-based stats.
Identities = 16/83 (19%), Positives = 39/83 (47%), Gaps = 6/83 (7%)
Query 254 VKIVRIEK-ARDIPLGA---TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+++ + K +R+ PL + + + + G A ++G L GD++LE+NG
Sbjct 383 RRLMTLTKPSREAPLPFILLGGSEKGFGIFVDSVDSGSKATEAG-LKRGDQILEVNGQNF 441
Query 310 RGKDVNEVFDLLSDMHG-TLTFV 331
+++ ++L + ++T
Sbjct 442 ENIQLSKAMEILRNNTHLSITVK 464
>sp|O42565|LIMK1_XENLA LIM domain kinase 1 OS=Xenopus laevis OX=8355
GN=limk1 PE=2 SV=1
Length=615
Score = 48.1 bits (113), Expect = 2e-04, Method: Composition-based stats.
Identities = 26/143 (18%), Positives = 53/143 (37%), Gaps = 22/143 (15%)
Query 232 MQLEPITDERVYESIGQYGGETVKIVRI-----EKARDIPLGATVRNEMDSVIISRIVKG 286
+ P+ D S G TV +V + ++ + + + +V ++ +
Sbjct 142 FSVTPVID-----SPGSRSPHTVTLVSLPASDGKRGLSVSITPSCAEHSHTVRVTELDAD 196
Query 287 --GAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL---------IPS 335
G + +H GD +LEING IR ++E+ L+ + L + +PS
Sbjct 197 FLGP-DIQSSIHIGDRILEINGTPIRSVPLDEIDVLIQETSRLLQLTIEHDPHETPTMPS 255
Query 336 QQIKPPPAKETVIHVKAHFDYDP 358
+ ++ + D P
Sbjct 256 PCAEIAVRRQRPVMRSCSIDRSP 278
>sp|A2ALK8|PTN3_MOUSE Tyrosine-protein phosphatase non-receptor
type 3 OS=Mus musculus OX=10090 GN=Ptpn3 PE=1 SV=1
Length=913
Score = 48.1 bits (113), Expect = 2e-04, Method: Composition-based stats.
Identities = 17/76 (22%), Positives = 36/76 (47%), Gaps = 4/76 (5%)
Query 256 IVRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEKS-GLLHEGDEVLEINGIEIRG 311
++RI + G ++ +D +++SRI A+ L+EGD+++ ING +I
Sbjct 510 LIRITPDEEGRFGFNLKGGVDQKMPLVVSRINPESPADTCMPKLNEGDQIVLINGRDISE 569
Query 312 KDVNEVFDLLSDMHGT 327
++V + +
Sbjct 570 HTHDQVVMFIKASRES 585
>sp|O95153|RIMB1_HUMAN Peripheral-type benzodiazepine receptor-associated
protein 1 OS=Homo sapiens OX=9606 GN=TSPOAP1 PE=1
SV=2
Length=1857
Score = 48.5 bits (114), Expect = 3e-04, Method: Composition-based stats.
Identities = 37/224 (17%), Positives = 71/224 (32%), Gaps = 32/224 (14%)
Query 237 ITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNE--MDSVIISRIVKGGAAEKSGL 294
+ E + G+ +K+ + A G + +++ + A + L
Sbjct 1643 PNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRTGYIPCNMVAEVAVDSPAGRQQL 1702
Query 295 LHEG----DEVLE-------------INGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 337
L G D +LE G + + + L+PS
Sbjct 1703 LQRGYLSPDILLEGSGNGPFVYSTAHTTGPPPKPRRSKKAESEGPAQPCPGPPKLVPSAD 1762
Query 338 IKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVI-SQEDPNWWQAYREG 396
+K P + + A FDY+P + E L F+ GD++ V +D ++ G
Sbjct 1763 LKAPHS------MVAAFDYNPQESSPNMDVEAELPFRAGDVITVFGGMDDDGFYYGELNG 1816
Query 397 DEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKK 440
GLVP + E + P+ + ++
Sbjct 1817 ------QRGLVPSNFLEGPGPEAGGLDREPRTPQAESQRTRRRR 1854
Score = 38.5 bits (88), Expect = 0.24, Method: Composition-based stats.
Identities = 19/65 (29%), Positives = 27/65 (42%), Gaps = 8/65 (12%)
Query 352 AHFDYDP-SDDPYVPCRELGLSFQKGDILHVI-SQEDPNWWQAYREGDEDNQPLAGLVPG 409
A FDYDP S P E L F++G IL V ++ ++Q G G +P
Sbjct 1632 ALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGG------RTGYIPC 1685
Query 410 KSFQQ 414
+
Sbjct 1686 NMVAE 1690
>sp|Q1IHU1|MIAA_KORVE tRNA dimethylallyltransferase OS=Koribacter
versatilis (strain Ellin345) OX=204669 GN=miaA PE=3 SV=1
Length=307
Score = 47.4 bits (111), Expect = 3e-04, Method: Composition-based stats.
Identities = 26/167 (16%), Positives = 47/167 (28%), Gaps = 23/167 (14%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHT--------TRSRRDQEVAGRDYHF 530
+L+GP G+ L L + + T +E +H
Sbjct 4 PLLFVLLGPTGSGKTSLSIALAERFGGEIVNCDSVAVYRELDIGTAKPTHEERESVPHHL 63
Query 531 VSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL 590
+ AG E+ + ++ + + GK L + + L
Sbjct 64 FDVLPPTEPMTAG---EYARRA-------REVLKDIASRGK---LPIVVGGTGLYLRALL 110
Query 591 KPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGH 637
F P E LR L + + P L I+ + + H
Sbjct 111 DGL--FAGPERSEELREHLRRREQERGPTYLHRILSRMDRVAAAKIH 155
>sp|Q578K3|FBPC_BRUAB Fe(3+) ions import ATP-binding protein FbpC
OS=Brucella abortus biovar 1 (strain 9-941) OX=262698 GN=fbpC
PE=3 SV=1
Length=353
Score = 47.4 bits (111), Expect = 3e-04, Method: Composition-based stats.
Identities = 27/219 (12%), Positives = 57/219 (26%), Gaps = 40/219 (18%)
Query 464 LTYEEMSL----------YHQPANRKRPIILIGPQNCGQNELRQRLMN-KEKDRFASAVP 512
+T+E ++ + L+GP CG+ + L + +
Sbjct 9 VTFENVTKKFGNFTALPNLSLTVEPGTLVTLLGPSGCGKTTTLRLLAGLEHPTSGRILIG 68
Query 513 HTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKI 572
+ F S F + +E+ + G + R+ G
Sbjct 69 GKDVTNLPANERDVSMVFQSYALFPHMTS----LENVAYGLESSGFKKNEARERAEEGLK 124
Query 573 CL--------LSLRTQSLKTLRNSDLKPYI----IFIAPPSQERLRALLAKEGKNPKPEE 620
+ L + R + + + + + L A L + + E
Sbjct 125 LVGLGGMGHRLPAELSGGQQQRVAVARALVLEPQVLLLDEPLSTLDARLRRRVRTEIREL 184
Query 621 LREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
+ + F V D D+A +I
Sbjct 185 QQRLG-------------FTAVYVTHDQDEALAVSDTII 210
>sp|Q2YKX3|FBPC_BRUA2 Fe(3+) ions import ATP-binding protein FbpC
OS=Brucella abortus (strain 2308) OX=359391 GN=fbpC PE=3
SV=1
Length=353
Score = 47.4 bits (111), Expect = 3e-04, Method: Composition-based stats.
Identities = 27/219 (12%), Positives = 57/219 (26%), Gaps = 40/219 (18%)
Query 464 LTYEEMSL----------YHQPANRKRPIILIGPQNCGQNELRQRLMN-KEKDRFASAVP 512
+T+E ++ + L+GP CG+ + L + +
Sbjct 9 VTFENVTKKFGNFTALPNLSLTVEPGTLVTLLGPSGCGKTTTLRLLAGLEHPTSGRILIG 68
Query 513 HTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKI 572
+ F S F + +E+ + G + R+ G
Sbjct 69 GKDVTNLPANERDVSMVFQSYALFPHMTS----LENVAYGLESSGFKKNEARERAEEGLK 124
Query 573 CL--------LSLRTQSLKTLRNSDLKPYI----IFIAPPSQERLRALLAKEGKNPKPEE 620
+ L + R + + + + + L A L + + E
Sbjct 125 LVGLGGMGHRLPAELSGGQQQRVAVARALVLEPQVLLLDEPLSTLDARLRRRVRTEIREL 184
Query 621 LREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
+ + F V D D+A +I
Sbjct 185 QQRLG-------------FTAVYVTHDQDEALAVSDTII 210
>sp|Q8WWI1|LMO7_HUMAN LIM domain only protein 7 OS=Homo sapiens
OX=9606 GN=LMO7 PE=1 SV=3
Length=1683
Score = 48.1 bits (113), Expect = 3e-04, Method: Composition-based stats.
Identities = 14/66 (21%), Positives = 30/66 (45%), Gaps = 1/66 (2%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
+ + G T++ ++ + ++ + G AE S L DE++ IN + D E + +
Sbjct 1050 GKSLDFGFTIKWDIPGIFVASVEAGSPAEFS-QLQVDDEIIAINNTKFSYNDSKEWEEAM 1108
Query 322 SDMHGT 327
+ T
Sbjct 1109 AKAQET 1114
>sp|Q9VCX1|RGS_DROME Regulator of G-protein signaling loco OS=Drosophila
melanogaster OX=7227 GN=loco PE=1 SV=2
Length=1541
Score = 48.1 bits (113), Expect = 3e-04, Method: Composition-based stats.
Identities = 16/83 (19%), Positives = 38/83 (46%), Gaps = 3/83 (4%)
Query 254 VKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
++ V + + + G T+ + +S I+ AE++G L GD ++ +NG+ +
Sbjct 69 IRTVEVRRGYN-GFGFTISGQ-QPCRLSCIISSSPAEQAG-LRSGDFLISVNGLNVSKLP 125
Query 314 VNEVFDLLSDMHGTLTFVLIPSQ 336
V L+ + G++ + +
Sbjct 126 HETVVQLIGNSFGSIRMQIAENY 148
>sp|Q8BMA3|CNKR3_MOUSE Connector enhancer of kinase suppressor
of ras 3 OS=Mus musculus OX=10090 GN=Cnksr3 PE=1 SV=1
Length=555
Score = 47.7 bits (112), Expect = 3e-04, Method: Composition-based stats.
Identities = 15/71 (21%), Positives = 34/71 (48%), Gaps = 1/71 (1%)
Query 264 DIPLGATVRNEMDSV-IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
LG +++ D + +I+ + A++S +H GDEV+++N + G + + L
Sbjct 220 GEGLGMYIKSTYDGLHVITGTTENSPADRSQKIHAGDEVIQVNRQTVVGWQLKNLVRKLR 279
Query 323 DMHGTLTFVLI 333
+ + +L
Sbjct 280 ENPTGVVLLLK 290
>sp|Q9NZN5|ARHGC_HUMAN Rho guanine nucleotide exchange factor
12 OS=Homo sapiens OX=9606 GN=ARHGEF12 PE=1 SV=1
Length=1544
Score = 48.1 bits (113), Expect = 3e-04, Method: Composition-based stats.
Identities = 25/94 (27%), Positives = 43/94 (46%), Gaps = 4/94 (4%)
Query 255 KIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
+ V I+K D G TV + + V + + + GAA ++G + GD ++++NG + +
Sbjct 71 RCVIIQK-DDNGFGLTVSGD-NPVFVQSVKEDGAAMRAG-VQTGDRIIKVNGTLVTHSNH 127
Query 315 NEVFDLLSDMHG-TLTFVLIPSQQIKPPPAKETV 347
EV L+ LT P + P A V
Sbjct 128 LEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEV 161
>sp|P09769|FGR_HUMAN Tyrosine-protein kinase Fgr OS=Homo sapiens
OX=9606 GN=FGR PE=1 SV=2
Length=529
Score = 47.7 bits (112), Expect = 3e-04, Method: Composition-based stats.
Identities = 13/62 (21%), Positives = 26/62 (42%), Gaps = 11/62 (18%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DY+ + L+F KG+ H+++ + +WW+A + G +P
Sbjct 84 ALYDYEARTEDD-------LTFTKGEKFHILNNTEGDWWEAR----SLSSGKTGCIPSNY 132
Query 412 FQ 413
Sbjct 133 VA 134
>sp|Q14511|CASL_HUMAN Enhancer of filamentation 1 OS=Homo sapiens
OX=9606 GN=NEDD9 PE=1 SV=1
Length=834
Score = 47.7 bits (112), Expect = 3e-04, Method: Composition-based stats.
Identities = 31/132 (23%), Positives = 48/132 (36%), Gaps = 18/132 (14%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQED---PNWWQAYREGDEDNQPLAGLV 407
+A +D P C E L+F+KGDIL VI Q WW G G+V
Sbjct 9 RALYDNVPE------CAE-ELAFRKGDILTVIEQNTGGLEGWWLCSLHG------RQGIV 55
Query 408 PGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYE 467
PG + M++T ++P + K + A ++ Y +Y+
Sbjct 56 PGNRVKLLIGPMQETASSHEQPASGLMQQTFGQQKLYQVPNPQAAPRDTIYQVP--PSYQ 113
Query 468 EMSLYHQPANRK 479
+Y P
Sbjct 114 NQGIYQVPTGHG 125
>sp|G9CGD6|CNIPF_HUMAN CNK3/IPCEF1 fusion protein OS=Homo sapiens
OX=9606 GN=CNK3/IPCEF1 PE=1 SV=1
Length=899
Score = 47.7 bits (112), Expect = 3e-04, Method: Composition-based stats.
Identities = 15/71 (21%), Positives = 34/71 (48%), Gaps = 1/71 (1%)
Query 264 DIPLGATVRNEMDSV-IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
LG +++ D + +I+ + A++S +H GDEV+++N + G + + L
Sbjct 220 GEGLGMYIKSTYDGLHVITGTTENSPADRSQKIHAGDEVIQVNQQTVVGWQLKNLVKKLR 279
Query 323 DMHGTLTFVLI 333
+ + +L
Sbjct 280 ENPTGVVLLLK 290
>sp|O15085|ARHGB_HUMAN Rho guanine nucleotide exchange factor
11 OS=Homo sapiens OX=9606 GN=ARHGEF11 PE=1 SV=1
Length=1522
Score = 48.1 bits (113), Expect = 3e-04, Method: Composition-based stats.
Identities = 25/111 (23%), Positives = 47/111 (42%), Gaps = 4/111 (4%)
Query 229 EQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGA 288
+ + + + R + G + V I+K + G TV + V++ + GGA
Sbjct 20 DSAPERKSPSHHRQPSDASETTGLVQRCVIIQKDQH-GFGFTVSGDRI-VLVQSVRPGGA 77
Query 289 AEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
A K+G + EGD ++++NG + EV L+ + L+ S
Sbjct 78 AMKAG-VKEGDRIIKVNGTMVTNSSHLEVVKLIK-SGAYVALTLLGSSPSS 126
>sp|Q6FN49|HSE1_CANGA Class E vacuolar protein-sorting machinery
protein HSE1 OS=Candida glabrata (strain ATCC 2001 / BCRC
20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593
GN=HSE1 PE=3 SV=1
Length=450
Score = 47.4 bits (111), Expect = 3e-04, Method: Composition-based stats.
Identities = 25/112 (22%), Positives = 47/112 (42%), Gaps = 7/112 (6%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
V+A +D + ++ LSF+KGD++ V+ Q +WW+ G PL + P
Sbjct 217 VRALYDLNANEQDE-------LSFRKGDVIVVLEQVYRDWWRGSLHGKIGIFPLNYVTPI 269
Query 410 KSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNE 461
+Q IEE + + K + K L N++ ++++
Sbjct 270 TEPSPVESQREQQIEEGVLSQAQNVQVLSAKMQMASGKGLSELNQDPEFNDL 321
>sp|Q99MJ6|NHRF4_MOUSE Na(+)/H(+) exchange regulatory cofactor
NHE-RF4 OS=Mus musculus OX=10090 GN=Nherf4 PE=1 SV=1
Length=498
Score = 47.4 bits (111), Expect = 4e-04, Method: Composition-based stats.
Identities = 14/106 (13%), Positives = 38/106 (36%), Gaps = 3/106 (3%)
Query 233 QLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSV--IISRIVKGGAAE 290
++ + + + + K + G ++ + ++ R+ G +A+
Sbjct 26 DNPVLSLAEDQDQSDPWNLHRPRFCLLSKEEEKTFGFHLQQHLGKADHVVCRVDPGTSAQ 85
Query 291 KSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQ 336
+ G L EGD +L +N + +D V + + ++
Sbjct 86 RQG-LREGDRILAVNNNIVAHEDHAVVVRYIRASGPRVLLTVLAQH 130
Score = 47.4 bits (111), Expect = 4e-04, Method: Composition-based stats.
Identities = 42/252 (17%), Positives = 79/252 (31%), Gaps = 53/252 (21%)
Query 94 PPKTGIDNPMF------DTEEGIVLESPHYAVKILEIEDLFSSLKHIQHTLVDSQS---Q 144
P+ GIDNP+ D + L P + + E E F H+Q L + +
Sbjct 20 NPRLGIDNPVLSLAEDQDQSDPWNLHRPRFCLLSKEEEKTFG--FHLQQHLGKADHVVCR 77
Query 145 EDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKE 204
D Q ++ ++N I H ++ V++ +
Sbjct 78 VDPGTSAQRQGLREGDRILAVNNNIVAH------------------EDHAVVVRYIRASG 119
Query 205 GQELTALLNTPHIQALLLAHDKV----AEQEMQLEPITDERVYESIGQYGGETVKIVRIE 260
+ L +L HD + ++ +
Sbjct 120 PRVLLTVLAQ-------HVHDVARVLQGSDAFLCPTLPSGVRP-----------RLCHVV 161
Query 261 KARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDL 320
K G +V + + GGAAE++G + G +LE+NG + N++
Sbjct 162 KDEG-GFGFSVTHGSRGPFWLVLSAGGAAERAG-VPPGARLLEVNGASVEKLTYNQLNRK 219
Query 321 LSDMHGTLTFVL 332
L +T ++
Sbjct 220 LWQSGDQVTLLV 231
Score = 46.2 bits (108), Expect = 9e-04, Method: Composition-based stats.
Identities = 24/119 (20%), Positives = 46/119 (39%), Gaps = 9/119 (8%)
Query 220 LLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD--- 276
LL+A +V EQ QL + G + + IEK + G +R E
Sbjct 229 LLVAGLEVEEQCHQLG--MPLAAPLAEGWALPAKPRCLNIEKGPE-GFGFLLREEKGLDG 285
Query 277 --SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
+ + G A+K+G + GD ++ + G + G E + ++ +++
Sbjct 286 RLGQFLWDVDPGLPADKAG-MKAGDRLVAVAGESVDGLGHEETVSRIRAQGSCVSLIVV 343
Score = 45.0 bits (105), Expect = 0.002, Method: Composition-based stats.
Identities = 17/66 (26%), Positives = 28/66 (42%), Gaps = 1/66 (2%)
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
+ IS++ GG+ ++G L GD VLE+NG + G + L++
Sbjct 407 FRLCCVASGPCLFISQVTPGGSTARAG-LQVGDTVLEVNGYPVGGDSELDRLQQLTEAEP 465
Query 327 TLTFVL 332
L L
Sbjct 466 PLCLKL 471
>sp|Q2K8C8|FBPC_RHIEC Fe(3+) ions import ATP-binding protein FbpC
OS=Rhizobium etli (strain CFN 42 / ATCC 51251) OX=347834
GN=fbpC PE=3 SV=1
Length=353
Score = 47.0 bits (110), Expect = 4e-04, Method: Composition-based stats.
Identities = 25/194 (13%), Positives = 51/194 (26%), Gaps = 30/194 (15%)
Query 479 KRPIILIGPQNCGQNELRQRLMN-KEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ L+GP CG+ + L + + + F S F
Sbjct 34 GTLVTLLGPSGCGKTTTLRMLAGLEHPTSGRILIGGADVTMLPANERDVSMVFQSYALFP 93
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICL--------LSLRTQSLKTLRNSD 589
+ +++ + G R+ G + L + R +
Sbjct 94 HMTS----LDNVAYGLQSSGLGKKEAREKAEEGLKLVGLAGMGHRLPAELSGGQQQRVAV 149
Query 590 LKPYI----IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVN 645
+ + + + L A L + + E + + F V
Sbjct 150 ARALVLEPQVLLLDEPLSNLDARLRRRVRTEIRELQQRLG-------------FTAVYVT 196
Query 646 SDLDKAYQELLRLI 659
D D+A R+I
Sbjct 197 HDQDEALAVSDRII 210
>sp|Q92WJ0|FBPC1_RHIME Fe(3+) ions import ATP-binding protein
FbpC 1 OS=Rhizobium meliloti (strain 1021) OX=266834 GN=fbpC1
PE=3 SV=1
Length=353
Score = 47.0 bits (110), Expect = 4e-04, Method: Composition-based stats.
Identities = 26/194 (13%), Positives = 51/194 (26%), Gaps = 30/194 (15%)
Query 479 KRPIILIGPQNCGQNELRQRLMN-KEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ L+GP CG+ + L + + + F S F
Sbjct 34 GTLVTLLGPSGCGKTTTLRMLAGLEHPTSGRILIGGKDVTMLPANERDVSMVFQSYALFP 93
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICL--------LSLRTQSLKTLRNSD 589
A +++ + G R+ G + L + R +
Sbjct 94 HMNA----LDNVAYGLESSGMRRKEARERAEEGLALVGLPGMGQRLPAELSGGQQQRVAV 149
Query 590 LKPYI----IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVN 645
+ + + + L A L + + E + + F V
Sbjct 150 ARALVLEPQVLLLDEPLSNLDARLRRRVRTEIRELQQRLG-------------FTAVYVT 196
Query 646 SDLDKAYQELLRLI 659
D D+A R+I
Sbjct 197 HDQDEALAVSDRII 210
>sp|P42681|TXK_HUMAN Tyrosine-protein kinase TXK OS=Homo sapiens
OX=9606 GN=TXK PE=1 SV=3
Length=527
Score = 47.4 bits (111), Expect = 4e-04, Method: Composition-based stats.
Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 19/102 (19%)
Query 321 LSDMHGTLTFVLIPSQQIKPPPA-----KETVIHVKAHFDYDPSDDPYVPCRELGLSFQK 375
LS+ + T + PS++ PP E I VKA +D+ P + PC L+ ++
Sbjct 53 LSNKKQSNTGRVQPSKRKPLPPLPPSEVAEEKIQVKALYDFLPRE----PCN---LALRR 105
Query 376 GDILHVISQEDPNWWQAY-REGDEDNQPLAGLVPGKSFQQQR 416
+ ++ + +P+WW+A R G+E GL+P + +
Sbjct 106 AEEYLILEKYNPHWWKARDRLGNE------GLIPSNYVTENK 141
>sp|Q8R4H2|ARHGC_MOUSE Rho guanine nucleotide exchange factor
12 OS=Mus musculus OX=10090 GN=Arhgef12 PE=1 SV=2
Length=1543
Score = 47.7 bits (112), Expect = 4e-04, Method: Composition-based stats.
Identities = 25/94 (27%), Positives = 43/94 (46%), Gaps = 4/94 (4%)
Query 255 KIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
+ V I+K D G TV + + V + + + GAA ++G + GD ++++NG + +
Sbjct 71 RCVIIQK-DDNGFGLTVSGD-NPVFVQSVKEDGAAMRAG-VQTGDRIIKVNGTLVTHSNH 127
Query 315 NEVFDLLSDMHG-TLTFVLIPSQQIKPPPAKETV 347
EV L+ LT P + P A V
Sbjct 128 LEVVKLIRSGSYVALTVQGRPPGSPQIPLADSEV 161
>sp|P42784|CTPA_PICP2 Carboxyl-terminal-processing protease OS=Picosynechococcus
sp. (strain ATCC 27264 / PCC 7002 / PR-6)
OX=32049 GN=ctpA PE=3 SV=2
Length=414
Score = 47.0 bits (110), Expect = 4e-04, Method: Composition-based stats.
Identities = 23/129 (18%), Positives = 53/129 (41%), Gaps = 1/129 (1%)
Query 211 LLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGAT 270
L+ ++ L D+ E ++ + D+ + ++K+ + + L
Sbjct 60 LIRQKFLKRPLKTRDEAYEAVGEMLALLDDPYTRLLRPEQYRSLKVSTSGELSGVGLQIN 119
Query 271 VRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTF 330
V E+D + + + G AE +G + D++L I+GI+ R + E + G+
Sbjct 120 VNPEVDVLEVILPLPGSPAEAAG-IEAKDQILAIDGIDTRNIGLEEAAARMRGKKGSTVS 178
Query 331 VLIPSQQIK 339
+ + S +
Sbjct 179 LTVKSPKTD 187
>sp|O75791|GRAP2_HUMAN GRB2-related adapter protein 2 OS=Homo
sapiens OX=9606 GN=GRAP2 PE=1 SV=1
Length=330
Score = 47.0 bits (110), Expect = 4e-04, Method: Composition-based stats.
Identities = 16/94 (17%), Positives = 34/94 (36%), Gaps = 16/94 (17%)
Query 315 NEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQ 374
+E+ L T L + +++ +A +D++ +D L F
Sbjct 250 SEMNAALMHRRHTDPVQLQAAGRVRWA---------RALYDFEALEDDE-------LGFH 293
Query 375 KGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
G+++ V+ +P+WW P + P
Sbjct 294 SGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAP 327
>sp|P42522|MYOC_DICDI Myosin IC heavy chain OS=Dictyostelium discoideum
OX=44689 GN=myoC PE=1 SV=2
Length=1182
Score = 47.7 bits (112), Expect = 4e-04, Method: Composition-based stats.
Identities = 19/97 (20%), Positives = 35/97 (36%), Gaps = 13/97 (13%)
Query 320 LLSDMHGTLTFVLIPSQQIKPPPAKETVIHVK--AHFDYDPSDDPYVPCRELGLSFQKGD 377
++ G I Q P + A ++YD L+F++ D
Sbjct 1096 MMKKPAGQPMMKPIAKPQPTPMKKPAAPPPQQYIALYEYDAMQPDE-------LTFKEND 1148
Query 378 ILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ 414
++++I + D +WWQ G++P QQ
Sbjct 1149 VINLIKKVDADWWQGELV----RTKQIGMLPSNYVQQ 1181
>sp|Q4KLN0|SDCB2_RAT Syntenin-2 OS=Rattus norvegicus OX=10116
GN=Sdcbp2 PE=1 SV=1
Length=296
Score = 46.6 bits (109), Expect = 4e-04, Method: Composition-based stats.
Identities = 20/169 (12%), Positives = 51/169 (30%), Gaps = 6/169 (4%)
Query 180 FPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHD-----KVAEQEMQL 234
P + + A + + + E +L + + L D + Q+
Sbjct 31 MPTLPASMASAPPLSELYPNLAELESYMGLSLSSQEVQKNLSQIPDGDNMVITSPGPGQV 90
Query 235 EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGL 294
+ V+ + + K G ++ + + + A G
Sbjct 91 TAPVSGNDLGVLRAEIKPGVREIHLCKDERGKTGLRLQAVDKGLFVQLVQANTPASLVG- 149
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPA 343
L GD++L+I+G + G ++ L +++ + +
Sbjct 150 LRFGDQILQIDGCDCAGWSTHKAQKALKKASAEKIVMVVRDRPFQRTVT 198
Score = 46.2 bits (108), Expect = 5e-04, Method: Composition-based stats.
Identities = 20/80 (25%), Positives = 38/80 (48%), Gaps = 5/80 (6%)
Query 255 KIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
+ V + K +G ++ I +VKG +A ++GLL V E+NG + G
Sbjct 195 RTVTMHKDSSGQVGFFIKKGK----IVSVVKGSSAARNGLL-TNHYVCEVNGQNVIGLKD 249
Query 315 NEVFDLLSDMHGTLTFVLIP 334
++ ++L+ +T +IP
Sbjct 250 KKIIEILTTAGNVITLTIIP 269
>sp|B1LY53|PHNN_METRJ Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Methylobacterium radiotolerans (strain ATCC 27329 / DSM
1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 / 0-1) OX=426355
GN=phnN PE=3 SV=1
Length=176
Score = 45.0 bits (105), Expect = 4e-04, Method: Composition-based stats.
Identities = 30/175 (17%), Positives = 54/175 (31%), Gaps = 37/175 (21%)
Query 481 PIILIGPQNCGQNELRQRLMNKE--KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
++++GP G++ L + R+ TR E + AF
Sbjct 5 LVLVVGPSGAGKDTLLRLARAALAGDPRYVFPRRLVTRPPSADEDNDE----IDEAAFAE 60
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR---TQSLKTLRNSDLKPYII 595
AAG+F Y ++V + + G + + ++ R S + ++
Sbjct 61 GCAAGRFTLSWRAHGLGYALP-EAVGRRVAEGHVVVCNVSRRVVAGA---RESGRRVSVV 116
Query 596 FI-APPSQ-------------ERLRALLAKEG----------KNPKPEELREIIE 626
I APP L A LA+EG E ++
Sbjct 117 EITAPPEILARRIAARGRAQDGDLAARLAREGGVTADLTILNTGAADEAAARLVA 171
>sp|O89100|GRAP2_MOUSE GRB2-related adaptor protein 2 OS=Mus musculus
OX=10090 GN=Grap2 PE=1 SV=1
Length=322
Score = 46.6 bits (109), Expect = 4e-04, Method: Composition-based stats.
Identities = 17/94 (18%), Positives = 35/94 (37%), Gaps = 16/94 (17%)
Query 315 NEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQ 374
+EV L T L + +++ +A +D++ + E L F+
Sbjct 242 SEVNATLMHRRHTDPVQLQAAGRVRWA---------RALYDFEALE-------EDELGFR 285
Query 375 KGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
G+++ V+ +P+WW P + P
Sbjct 286 SGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAP 319
>sp|Q14155|ARHG7_HUMAN Rho guanine nucleotide exchange factor
7 OS=Homo sapiens OX=9606 GN=ARHGEF7 PE=1 SV=2
Length=803
Score = 47.4 bits (111), Expect = 5e-04, Method: Composition-based stats.
Identities = 18/76 (24%), Positives = 32/76 (42%), Gaps = 13/76 (17%)
Query 343 AKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQP 402
+ V+A F++ ++ E LSF KGD++HV E+ WW+ G
Sbjct 182 NSNNQLVVRAKFNFQQTN-------EDELSFSKGDVIHVTRVEEGGWWEGTLNG------ 228
Query 403 LAGLVPGKSFQQQREA 418
G P ++ + +
Sbjct 229 RTGWFPSNYVREVKAS 244
>sp|Q6DJJ6|RHN2A_XENLA Rhophilin-2-A OS=Xenopus laevis OX=8355
GN=rhpn2-a PE=2 SV=1
Length=683
Score = 47.4 bits (111), Expect = 5e-04, Method: Composition-based stats.
Identities = 41/244 (17%), Positives = 83/244 (34%), Gaps = 35/244 (14%)
Query 124 IEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMN--KASPPFP 181
I L+ S+ + Q+ +LL A + H
Sbjct 381 ISQLYDSMPEGLTAQTILKDQQQRTLL----GKAHLSKAIRSHEEAIRFSTLCSTLRQID 436
Query 182 LISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQ----LEPI 237
++ + ++ LK H++ + LL+ P D V++ E Q +
Sbjct 437 VLQKILSAFHQ-RSQLKFSQHQKPDDFLDLLSAP---------DIVSKTEYQAKTISPQL 486
Query 238 TDERVYESIGQYGGETV----------KIVRIEKARDIPLGATVRNEMDSVIISRIVKGG 287
+ ++V + + G +V + + I K G +R + +IS +
Sbjct 487 SKDKVTDIFQRLGPLSVFSVKQRWSAPRKICITKEDG-DFGFVLRGDCPVQVIS-LDPLC 544
Query 288 AAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMH-GTLTFVLIP-SQQIKPPPAKE 345
A G L EGD ++ + G + + ++V D+L ++ +I Q P K
Sbjct 545 PAATEG-LKEGDYIVSVAGKDCKWCSTSQVMDMLQATGKQSIEIQVISIQDQTYSMPTKS 603
Query 346 TVIH 349
+
Sbjct 604 ATYY 607
>sp|B8D5U4|KCY_DESA1 Cytidylate kinase OS=Desulfurococcus amylolyticus
(strain DSM 18924 / JCM 16383 / VKM B-2413 / 1221n)
OX=490899 GN=cmk PE=3 SV=1
Length=185
Score = 45.4 bits (106), Expect = 5e-04, Method: Composition-based stats.
Identities = 41/214 (19%), Positives = 77/214 (36%), Gaps = 65/214 (30%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+ GP G+ TT+++R E G Y A
Sbjct 4 IVFSGPPGSGK---------------------TTQAKRVAEYYGLKYF----------SA 32
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD------------ 589
F E+ + G S++ + ++ L + +L+T+R+SD
Sbjct 33 GSLFREYARRK----GVSLEELSRIALEDPSIDLEIDRMTLETVRDSDDIVIDGHLAAWI 88
Query 590 ---LKPYIIFIAPP-SQERLRALLAKE-----GKNPKPEELREIIEKTREMEQNNGHYFD 640
+ I++ P + L +A GK +RE ++ R ME +D
Sbjct 89 VSDIVDLKIYVTAPLTLRIL--RVAGRDNTPLGKALAETLIREYSQRRRFMEYYGIDIYD 146
Query 641 TAI----VNSDL---DKAYQELLRLINKLDTEPQ 667
T+I +N+ L ++A+ + +I+K+ E
Sbjct 147 TSIFDLTINTKLIGVEEAFNIIKSIIDKILKEKH 180
>sp|P53670|LIMK2_RAT LIM domain kinase 2 OS=Rattus norvegicus
OX=10116 GN=Limk2 PE=2 SV=1
Length=638
Score = 47.4 bits (111), Expect = 5e-04, Method: Composition-based stats.
Identities = 27/123 (22%), Positives = 51/123 (41%), Gaps = 13/123 (11%)
Query 234 LEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDS------VIISRI--VK 285
L P+ + ES+ +V ++ + + G +V E S V + + +
Sbjct 130 LAPMFERLSTESVQDQLPYSVTLISMPATTECRRGFSVSVESASSNYATTVQVKEVNRMH 189
Query 286 GGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKE 345
++ +H GD +LEING +R V EV D ++ TL ++ + P P +
Sbjct 190 ISPNNRN-AIHPGDRILEINGTPVRTLRVEEVEDAINQTSQTLQLLI----EHDPVPQRL 244
Query 346 TVI 348
+
Sbjct 245 DQL 247
>sp|Q28923|YES_CANLF Tyrosine-protein kinase Yes OS=Canis lupus
familiaris OX=9615 GN=YES1 PE=1 SV=3
Length=539
Score = 47.0 bits (110), Expect = 5e-04, Method: Composition-based stats.
Identities = 20/110 (18%), Positives = 34/110 (31%), Gaps = 25/110 (23%)
Query 347 VIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGL 406
I V A +DY+ LSF+ G+ +I+ + +WW+A G
Sbjct 90 TIFV-ALYDYEARTTED-------LSFKGGERFQIINNTEGDWWEARSI----ATGKNGY 137
Query 407 VPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKND 456
+P + + W K +K + L N
Sbjct 138 IPSNYVA-------------PADSIAAEEWYFGKMGRKDAERLLLNPGNQ 174
>sp|Q6P6U0|FGR_RAT Tyrosine-protein kinase Fgr OS=Rattus norvegicus
OX=10116 GN=Fgr PE=1 SV=1
Length=517
Score = 47.0 bits (110), Expect = 5e-04, Method: Composition-based stats.
Identities = 16/67 (24%), Positives = 27/67 (40%), Gaps = 12/67 (18%)
Query 347 VIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGL 406
I V A +DY+ L+F KG+ H+++ + +WW+A + G
Sbjct 68 TIFV-ALYDYEARTGDD-------LTFTKGEKFHILNNTEYDWWEAR----SLSSGRTGY 115
Query 407 VPGKSFQ 413
VP
Sbjct 116 VPSNYVA 122
>sp|E9Q634|MYO1E_MOUSE Unconventional myosin-Ie OS=Mus musculus
OX=10090 GN=Myo1e PE=1 SV=1
Length=1107
Score = 47.4 bits (111), Expect = 5e-04, Method: Composition-based stats.
Identities = 24/119 (20%), Positives = 36/119 (30%), Gaps = 25/119 (21%)
Query 306 GIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHV----------KAHFD 355
G + + + D L + + +PPPA KA +
Sbjct 1003 GSDRLSQTPESL-DFLKVPDQGVA-GVRRQTSSRPPPAGGRPKPQPKPKPQVPQCKALYA 1060
Query 356 YDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ 414
YD D LSF DI+ +I ++ WW G GL P +
Sbjct 1061 YDAQDTDE-------LSFNANDIIDIIKEDPSGWWTGRLRGK------QGLFPNNYVTK 1106
>sp|Q5U2U2|CRKL_RAT Crk-like protein OS=Rattus norvegicus OX=10116
GN=Crkl PE=1 SV=1
Length=303
Score = 46.2 bits (108), Expect = 5e-04, Method: Composition-based stats.
Identities = 21/97 (22%), Positives = 43/97 (44%), Gaps = 23/97 (24%)
Query 329 TFVLIPSQQIKPPP-----------AKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGD 377
T ++ P+ + PP A+E + +V+ +D+ P +D L F+KG+
Sbjct 96 TTLIEPAPRYPNPPMGSVSAPNLSTAEENLEYVRTLYDF-PGNDAED------LPFKKGE 148
Query 378 ILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ 414
+L +I + + WW A + G++P ++
Sbjct 149 LLVIIEKPEEQWWSAR-----NKDGRVGMIPVPYVEK 180
>sp|Q9QY53|NPHP1_MOUSE Nephrocystin-1 OS=Mus musculus OX=10090
GN=Nphp1 PE=1 SV=1
Length=687
Score = 47.0 bits (110), Expect = 5e-04, Method: Composition-based stats.
Identities = 20/79 (25%), Positives = 34/79 (43%), Gaps = 12/79 (15%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
+Q P A+ + A D+ L+F+KGD+LH+I ++ WW A
Sbjct 145 QEQASPKQAETETVTYIALGDFAAQQTGD-------LTFKKGDVLHIIEKKPDGWWLAK- 196
Query 395 EGDEDNQPLAGLVPGKSFQ 413
D + + GL+P +
Sbjct 197 ----DAEGVEGLIPRTYLE 211
>sp|P42682|TXK_MOUSE Tyrosine-protein kinase TXK OS=Mus musculus
OX=10090 GN=Txk PE=1 SV=1
Length=527
Score = 47.0 bits (110), Expect = 5e-04, Method: Composition-based stats.
Identities = 18/71 (25%), Positives = 32/71 (45%), Gaps = 12/71 (17%)
Query 348 IHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLV 407
I VKA +D+ P + L+ ++ + ++ + DP+WW+A D GL+
Sbjct 85 IQVKALYDFLPREPGN-------LALKRAEEYLILERCDPHWWKAR-----DRFGNEGLI 132
Query 408 PGKSFQQQREA 418
P + R A
Sbjct 133 PSNYVTENRLA 143
>sp|Q8U6M1|FBPC_AGRFC Fe(3+) ions import ATP-binding protein FbpC
OS=Agrobacterium fabrum (strain C58 / ATCC 33970) OX=176299
GN=fbpC PE=3 SV=1
Length=353
Score = 46.6 bits (109), Expect = 5e-04, Method: Composition-based stats.
Identities = 27/194 (14%), Positives = 52/194 (27%), Gaps = 30/194 (15%)
Query 479 KRPIILIGPQNCGQNELRQRLMN-KEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ L+GP CG+ + L + + + + F S F
Sbjct 34 GTLVTLLGPSGCGKTTTLRMLAGLEHPNSGRILIGGKDVTMLPANERDVSMVFQSYALFP 93
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICL--------LSLRTQSLKTLRNSD 589
A +++ + G R+ G + L + R +
Sbjct 94 HMSA----LDNVAYGLQSSGLKKAEAREKAEEGLKLVGLAGMGHRLPAELSGGQQQRVAV 149
Query 590 LKPYI----IFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVN 645
+ + + + L A L + + E + I F V
Sbjct 150 ARALVLEPQVLLLDEPLSNLDARLRRRVRTDIRELQQRIG-------------FTAVYVT 196
Query 646 SDLDKAYQELLRLI 659
D D+A R+I
Sbjct 197 HDQDEALAVSDRII 210
>sp|Q9ES28|ARHG7_MOUSE Rho guanine nucleotide exchange factor
7 OS=Mus musculus OX=10090 GN=Arhgef7 PE=1 SV=2
Length=862
Score = 47.0 bits (110), Expect = 6e-04, Method: Composition-based stats.
Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 15/95 (16%)
Query 322 SDMHGTLTFVLIPSQQIKPPPAKET--VIHVKAHFDYDPSDDPYVPCRELGLSFQKGDIL 379
S + T L+ SQ T + V+A F++ ++ E LSF KGD++
Sbjct 138 SQSSHSRTSKLLQSQYRSLDMTDNTNSQLVVRAKFNFQQTN-------EDELSFSKGDVI 190
Query 380 HVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ 414
HV E+ WW+ G G P ++
Sbjct 191 HVTRVEEGGWWEGTHNG------RTGWFPSNYVRE 219
>sp|O74749|HSE1_SCHPO Class E vacuolar protein-sorting machinery
protein hse1 OS=Schizosaccharomyces pombe (strain 972 / ATCC
24843) OX=284812 GN=hse1 PE=3 SV=1
Length=373
Score = 46.6 bits (109), Expect = 6e-04, Method: Composition-based stats.
Identities = 18/98 (18%), Positives = 38/98 (39%), Gaps = 14/98 (14%)
Query 331 VLIPSQQIKPPPAKETVIH-VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNW 389
Q+ + + + V+A +D+ ++ + LSF+KGDI+ V+ +W
Sbjct 200 KTNQRQESNLATSPASTVSRVRALYDFAATE-------QGELSFKKGDIILVLESVYKDW 252
Query 390 WQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDK 427
W+ + G+ P Q+ E + +
Sbjct 253 WKGSC------KNAVGIFPVNYVQRVVEPTIEQQRQSA 284
>sp|Q8IR79|LIMK1_DROME LIM domain kinase 1 OS=Drosophila melanogaster
OX=7227 GN=LIMK1 PE=1 SV=1
Length=1257
Score = 47.0 bits (110), Expect = 6e-04, Method: Composition-based stats.
Identities = 20/103 (19%), Positives = 32/103 (31%), Gaps = 20/103 (19%)
Query 250 GGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVK---------GGAAEKSGL------ 294
++++V I K L D RI AE+
Sbjct 168 PMHSIRLVEIPKDATPGLRVDGVALDDGCPTVRITDLFCNFFLWLTSMAEQCCGAPYRID 227
Query 295 -----LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
LH GD +LE+NG + V ++ L+ L +
Sbjct 228 VNLTNLHIGDRILEVNGTPVSDSSVEQIDKLIRSNEKMLQLTV 270
>sp|Q9ES67|ARHGB_RAT Rho guanine nucleotide exchange factor 11
OS=Rattus norvegicus OX=10116 GN=Arhgef11 PE=1 SV=1
Length=1527
Score = 47.0 bits (110), Expect = 6e-04, Method: Composition-based stats.
Identities = 23/90 (26%), Positives = 42/90 (47%), Gaps = 3/90 (3%)
Query 233 QLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKS 292
+ P + ++ G + V I+K + G TV + V++ + GGAA K+
Sbjct 41 RTSPSHHRQPSDTSETTAGLVQRCVIIQKDQH-GFGFTVSGDRI-VLVQSVRPGGAAMKA 98
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
G + EGD ++++NG + EV L+
Sbjct 99 G-VKEGDRIIKVNGTMVTNSSHLEVVKLIK 127
>sp|Q5L4W4|DER_CHLAB GTPase Der OS=Chlamydia abortus (strain DSM
27085 / S26/3) OX=218497 GN=der PE=3 SV=1
Length=474
Score = 46.6 bits (109), Expect = 6e-04, Method: Composition-based stats.
Identities = 28/115 (24%), Positives = 42/115 (37%), Gaps = 13/115 (11%)
Query 467 EEMSLYHQP-ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRD--QEV 523
E+ + A++ I LIG N G++ + L+N+E+ VP TTR D
Sbjct 198 EDTAFSQSSVADKPLKIALIGRPNVGKSSIINALLNEER-CIIDNVPGTTRDNIDILYSH 256
Query 524 AGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
R Y F+ + IE S + I ICLL +
Sbjct 257 NDRSYLFIDTAGLRKMKSVKNSIEW---------ISSSRTEKAIARADICLLVID 302
>sp|Q8TF64|GIPC3_HUMAN PDZ domain-containing protein GIPC3 OS=Homo
sapiens OX=9606 GN=GIPC3 PE=1 SV=1
Length=312
Score = 46.2 bits (108), Expect = 6e-04, Method: Composition-based stats.
Identities = 22/87 (25%), Positives = 35/87 (40%), Gaps = 2/87 (2%)
Query 254 VKIVRIEKARDIPLGATVRNEMDS-VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
K V + K + LG T+ + I RI +G + + GD + IN I G
Sbjct 110 TKEVEVTK-TEDALGLTITDNGAGYAFIKRIKEGSIINRIEAVCVGDSIEAINDHSIVGC 168
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIK 339
EV +L ++ + F L Q +
Sbjct 169 RHYEVAKMLRELPKSQPFTLRLVQPKR 195
>sp|Q8JH64|BTK_CHICK Tyrosine-protein kinase BTK OS=Gallus gallus
OX=9031 GN=BTK PE=1 SV=1
Length=657
Score = 46.6 bits (109), Expect = 6e-04, Method: Composition-based stats.
Identities = 27/123 (22%), Positives = 43/123 (35%), Gaps = 13/123 (11%)
Query 291 KSGLLHEGDEVLEI-NGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIH 349
++ G ++LE NG G+ + L T V+ P P A +
Sbjct 156 QTAKNAMGCKILESRNGSLKAGRSHRKTKKPLPPTPEEDTMVMKPLPPEPAPSAAGEMKK 215
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
V A ++Y VP L QKG+ ++ + WW+A D G +P
Sbjct 216 VVALYNY-------VPMNVQDLQLQKGEDYLILEESHLPWWKAR-----DKNGREGYIPS 263
Query 410 KSF 412
Sbjct 264 NYV 266
>sp|Q256C5|DER_CHLFF GTPase Der OS=Chlamydia felis (strain Fe/C-56)
OX=264202 GN=der PE=3 SV=1
Length=475
Score = 46.6 bits (109), Expect = 7e-04, Method: Composition-based stats.
Identities = 29/115 (25%), Positives = 43/115 (37%), Gaps = 13/115 (11%)
Query 467 EEMSLYHQPA-NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRD--QEV 523
EE+ PA ++ I LIG N G++ + L+N+E+ +P TTR D
Sbjct 199 EEILFSKPPASDKPLKIALIGRPNVGKSSIINGLLNEER-CIIDNIPGTTRDNVDILYSH 257
Query 524 AGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
R Y F+ + IE S + I ICLL +
Sbjct 258 NDRSYLFIDTAGLRKMKSVKNSIEW---------ISSSRTEKAIARADICLLVID 303
>sp|P43669|PRC_SALTY Tail-specific protease OS=Salmonella typhimurium
(strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=prc
PE=3 SV=2
Length=682
Score = 46.6 bits (109), Expect = 7e-04, Method: Composition-based stats.
Identities = 29/159 (18%), Positives = 65/159 (41%), Gaps = 19/159 (12%)
Query 191 QEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHD----KVAEQEM--QLEPITDERVYE 244
E+ L KE +E I+ L + +A +++P T+
Sbjct 173 DELSLKLTGKSDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPR 232
Query 245 SIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEI 304
+ Q+ E + +GA ++ + D +I+ +V GG A KS + GD ++ +
Sbjct 233 NTEQFNTEMSLSL-------EGIGAVLQMDDDYTVINSLVAGGPAAKSKSISVGDRIVGV 285
Query 305 NG-----IEIRGKDVNEVFDLLSDMHGT-LTFVLIPSQQ 337
+++ G +++V L+ G+ + ++P+ +
Sbjct 286 GQAGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGK 324
>sp|C1D7Y5|PHNN_LARHH Ribose 1,5-bisphosphate phosphokinase PhnN
OS=Laribacter hongkongensis (strain HLHK9) OX=557598 GN=phnN
PE=3 SV=1
Length=410
Score = 46.2 bits (108), Expect = 8e-04, Method: Composition-based stats.
Identities = 35/206 (17%), Positives = 61/206 (30%), Gaps = 29/206 (14%)
Query 473 HQPANRKRPIILIGPQNCGQNEL----RQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDY 528
+ I ++GP G++ L R+RL + A + TR
Sbjct 220 SMRTETGQLIYVMGPSGAGKDSLLGYARERLAGQP---LVFAHRYITRPATAGSENHVA- 275
Query 529 HFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNS 588
+S F A G F YG V + +G + + R +
Sbjct 276 --LSEAEFALREAHGCFALSWRRNGLAYG-LGCEVTDWLAAGLVVV----VNGS---RAA 325
Query 589 DLKPYIIF--IAP----PSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTA 642
+ F + P S L A LA G+ + + +
Sbjct 326 LPQARQCFPGLKPLWITASPAVLAARLAARGRESADDIAARLAASAGFRPPADCR----V 381
Query 643 IVNS-DLDKAYQELLRLINKLDTEPQ 667
+ N +L A EL+ ++ +P
Sbjct 382 LCNDGELAVAGDELVAWLSSHCHQPI 407
>sp|A0A8I3PDQ1|CASL_CANLF Enhancer of filamentation 1 OS=Canis
lupus familiaris OX=9615 GN=NEDD9 PE=1 SV=1
Length=834
Score = 46.6 bits (109), Expect = 8e-04, Method: Composition-based stats.
Identities = 42/198 (21%), Positives = 74/198 (37%), Gaps = 44/198 (22%)
Query 346 TVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQED---PNWWQAYREGDEDNQP 402
+ +A +D P C E L+F+KGDIL VI Q WW G
Sbjct 4 RNLMARALYDNVPE------CAE-ELAFRKGDILTVIEQNTGGLEGWWLCSLHG------ 50
Query 403 LAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKV--LYNANKNDDYDN 460
G+VPG + +++T + + + L ++K +V ++A ++ Y
Sbjct 51 RQGIVPGNRVKLLIGPIQET--PSGQDQPTSGLMHQTFGQQKLYQVPNPHSAPRDTIYQV 108
Query 461 ---------EEILT---YEEMSLYHQPANRKRPI-----------ILIGPQNCGQNELRQ 497
++ T +E +Y P + +R I ++ P GQ + +
Sbjct 109 PPSYQHQGIYQVPTSHGIQEQDVYQVPPSVQRSIGAANGPHLSKKVVT-PVRTGQGYVYE 167
Query 498 RLMNKEKDRFASAVPHTT 515
+KD + HTT
Sbjct 168 YPSRHQKDIYDIPPSHTT 185
>sp|Q5SYB0|FRPD1_HUMAN FERM and PDZ domain-containing protein
1 OS=Homo sapiens OX=9606 GN=FRMPD1 PE=1 SV=1
Length=1578
Score = 46.6 bits (109), Expect = 8e-04, Method: Composition-based stats.
Identities = 18/105 (17%), Positives = 41/105 (39%), Gaps = 4/105 (4%)
Query 240 ERVYESIGQYGGETVKIVRIEKARDI-PLGATVRNEMDSVIISRIVKGGAAEKSGLLHEG 298
+ + Q V+I+K + G + + +++ + GG+A G L G
Sbjct 41 DGPARNPTQTLIPVRHTVKIDKDTLLQDYGFHISESLPLTVVA-VTAGGSAH--GKLFPG 97
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPA 343
D++L++N D+L + +L+ ++ P +
Sbjct 98 DQILQMNNEPAEDLSWERAVDILREAEDSLSITVVRCTSGVPKSS 142
>sp|Q86NH1|SYD1_CAEEL Rho GTPase-activating protein syd-1 OS=Caenorhabditis
elegans OX=6239 GN=syd-1 PE=2 SV=1
Length=987
Score = 46.6 bits (109), Expect = 8e-04, Method: Composition-based stats.
Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 7/99 (7%)
Query 255 KIVRIEKARDIPLGATVR-----NEMDSVIISRIVKGGAAEKSGLL-HEGDEVLEINGIE 308
++V I K LG +R + D V +SR K G + GDE+L IN +E
Sbjct 122 QLVEIIKKPGQSLGLYLREGNGKDRSDGVFVSRFGDNSELAKYGEVMRPGDEILTINNVE 181
Query 309 IRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV 347
+ +++V +LS L + S+ ++
Sbjct 182 VSMMSIDDVVLILSIPRR-LLLRIRYSKSMRHEIISSRS 219
>sp|B2TQ47|AROK_CLOBB Shikimate kinase OS=Clostridium botulinum
(strain Eklund 17B / Type B) OX=935198 GN=aroK PE=3 SV=1
Length=165
Score = 44.3 bits (103), Expect = 9e-04, Method: Composition-based stats.
Identities = 34/192 (18%), Positives = 70/192 (36%), Gaps = 48/192 (25%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRF---ASAVPH-TTRSRRDQEVAGRDYHFVSRQAFE 537
I LIG CG++ + + + + +F + T+++ + G DY
Sbjct 5 IFLIGMPGCGKSTIGEIIAKELMLKFIDMDICIEEKTSKTISELFEQGEDYF-------- 56
Query 538 ADIAAG---KFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYI 594
DI + + I++ + G + + ++LK +
Sbjct 57 RDIESETCKEIIKYDNVV-------------IATGGGVVKKDINIETLKN------NGLV 97
Query 595 IFIAPP------SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVN-SD 647
IFI P + R L K GK E + + ++ ++ + H +VN S
Sbjct 98 IFIDRPVEKIISDIDVSRRPLLKNGK----ERIIGLYKERYDIYKKACHK---IVVNGST 150
Query 648 LDKAYQELLRLI 659
+D+ E+ ++I
Sbjct 151 IDEVVGEIKKII 162
>sp|P53666|LIMK2_CHICK LIM domain kinase 2 OS=Gallus gallus OX=9031
GN=LIMK2 PE=2 SV=1
Length=642
Score = 46.2 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 27/107 (25%), Positives = 46/107 (43%), Gaps = 9/107 (8%)
Query 234 LEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMD------SVIISRI--VK 285
L P+ ++ ES+ + T+ ++ + A D G +V E V + + +
Sbjct 130 LTPMIEKHSTESLREQLPYTLTLISMPAATDGKRGFSVSVEGGCSSYATGVQVKEVNRMH 189
Query 286 GGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ +H D +LEING IR V EV DL+ TL ++
Sbjct 190 ISP-DVRNAIHPADRILEINGAPIRTLQVEEVEDLIRKTSQTLQLLI 235
>sp|Q22638|MICS1_CAEEL Mitochondrial scaffolding protein 1 OS=Caenorhabditis
elegans OX=6239 GN=mics-1 PE=3 SV=2
Length=269
Score = 45.4 bits (106), Expect = 0.001, Method: Composition-based stats.
Identities = 19/109 (17%), Positives = 40/109 (37%), Gaps = 10/109 (9%)
Query 225 DKVAEQEMQLEPITDERVY-ESIGQYGGETVKIVRIEK-ARDIPLGATVRNEMD------ 276
D V EQ D E + +V IEK ++ +
Sbjct 17 DPVYEQATDDMTFNDTTTDGNGQESVPLEALTVVEIEKTSKGFGFNIVGGTDNPHFVGDI 76
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMH 325
+ +S + ++ G++ GD++L +GI++ K +E ++ +
Sbjct 77 GIYVSSV--NSESKSYGVVRTGDKILSFDGIDMTYKTHDEAVEVFRSVK 123
>sp|P45306|PRC_HAEIN Tail-specific protease OS=Haemophilus influenzae
(strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421
GN=prc PE=3 SV=1
Length=695
Score = 46.2 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 18/77 (23%), Positives = 39/77 (51%), Gaps = 6/77 (8%)
Query 265 IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI-----EIRGKDVNEVFD 319
+G T+++E D + I +V G AE+S LH GD+++ + ++ G + ++ +
Sbjct 254 EGIGTTLQSEDDEISIKSLVPGAPAERSKKLHPGDKIIGVGQATGDIEDVVGWRLEDLVE 313
Query 320 LLSDMHGT-LTFVLIPS 335
+ GT + + P+
Sbjct 314 KIKGKKGTKVRLEIEPA 330
>sp|O35177|CASL_MOUSE Enhancer of filamentation 1 OS=Mus musculus
OX=10090 GN=Nedd9 PE=1 SV=2
Length=833
Score = 46.2 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 33/144 (23%), Positives = 51/144 (35%), Gaps = 29/144 (20%)
Query 346 TVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQED---PNWWQAYREGDEDNQP 402
+ +A +D P C E L+F+KGDIL VI Q WW G
Sbjct 4 RNLMARALYDNVPE------CAE-ELAFRKGDILTVIEQNTGGLEGWWLCSLHG------ 50
Query 403 LAGLVPGKSFQQQREAMKQTIE-EDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNE 461
G+VPG + +++T E P + + +K LY + +
Sbjct 51 RQGIVPGNRVKLLIGPVQETPGHEQPTPGPMHQTFGQQK--------LYQVPNSQAASRD 102
Query 462 EI----LTYEEMSLYHQPANRKRP 481
I +Y+ +Y P P
Sbjct 103 TIYQVPPSYQNQGIYQVPTGHGTP 126
>sp|Q9ULL8|SHRM4_HUMAN Protein Shroom4 OS=Homo sapiens OX=9606
GN=SHROOM4 PE=1 SV=3
Length=1493
Score = 46.2 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 26/125 (21%), Positives = 53/125 (42%), Gaps = 11/125 (9%)
Query 257 VRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
V+++ P G T++ ++ + +S+I GG A S + GDE++ ING + G
Sbjct 13 VQLQGGA--PWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVNINGTPLYGSR 70
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDP--SDDPYVPCRELGL 371
+ + G+ + + ++ P ++ HV + P + + P L
Sbjct 71 QEALILI----KGSFRILKLIVRRRNAPVSRPHSWHVAKLLEGCPEAATTMHFPSEAFSL 126
Query 372 SFQKG 376
S+ G
Sbjct 127 SWHSG 131
>sp|Q821L7|DER_CHLCV GTPase Der OS=Chlamydia caviae (strain ATCC
VR-813 / DSM 19441 / 03DC25 / GPIC) OX=227941 GN=der PE=3
SV=1
Length=474
Score = 45.8 bits (107), Expect = 0.001, Method: Composition-based stats.
Identities = 31/133 (23%), Positives = 49/133 (37%), Gaps = 21/133 (16%)
Query 459 DNEEILTYEEMSLYHQP---------ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFAS 509
+ E+L+ E +S Y + ++ I LIG N G++ + L+N+E+
Sbjct 182 PSMELLSKEPLSDYEEEEIPFSTTSAPDKPLKIALIGRPNVGKSSIINGLLNEER-CIID 240
Query 510 AVPHTTRSRRD--QEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVI 567
VP TTR D R Y F+ + IE S + I
Sbjct 241 NVPGTTRDNVDILYSHNDRSYLFIDTAGLRKMKSVKNSIEW---------ISSSRTEKAI 291
Query 568 NSGKICLLSLRTQ 580
+CLL + Q
Sbjct 292 ARADVCLLVIDAQ 304
>sp|Q8R1G6|PDLI2_MOUSE PDZ and LIM domain protein 2 OS=Mus musculus
OX=10090 GN=Pdlim2 PE=1 SV=1
Length=349
Score = 45.4 bits (106), Expect = 0.001, Method: Composition-based stats.
Identities = 19/89 (21%), Positives = 32/89 (36%), Gaps = 3/89 (3%)
Query 266 PLGATVRNEMD-SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
+ + +I++++ + G AE + L GD ++ ING E +
Sbjct 14 GFRISGGRDFHTPIIVTKVTERGKAEAAD-LRPGDIIVAINGQSAENMLHAEAQSKIRQS 72
Query 325 HGTLTFVLIPSQQIKP-PPAKETVIHVKA 352
L L SQ P E + V A
Sbjct 73 ASPLRLQLDRSQTASPGQTNGEGSLEVLA 101
>sp|Q5I0L6|CYTIP_RAT Cytohesin-interacting protein OS=Rattus norvegicus
OX=10116 GN=Cytip PE=2 SV=1
Length=359
Score = 45.4 bits (106), Expect = 0.001, Method: Composition-based stats.
Identities = 25/115 (22%), Positives = 44/115 (38%), Gaps = 11/115 (10%)
Query 244 ESIGQYGGETVKIVRIEKARDIPLGA---TVRNEMDSV-------IISRIVKGGAAEKSG 293
S+G + K+V +EK + G T R + ++ +I ++ + A +G
Sbjct 65 SSLGDFSCSQRKVVTVEKQDNGTFGFEIQTYRLQNQNICSSEVCTMICKVQEDSPAHCAG 124
Query 294 LLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVI 348
L GD +NG+ G +V DL+ LT + I E +
Sbjct 125 -LQVGDIFANVNGVSTEGFTHKQVVDLIRSSGNLLTIETLNGTMIHRRAELEAKL 178
>sp|G5EEW9|CNKR_CAEEL Connector enhancer of kinase suppressor
of ras OS=Caenorhabditis elegans OX=6239 GN=cnk-1 PE=2 SV=1
Length=801
Score = 46.2 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 25/112 (22%), Positives = 49/112 (44%), Gaps = 13/112 (12%)
Query 260 EKARDIPLGATVRNEMDSV-IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVF 318
++ +I G +++ V +IS I +G A+ + GDE+L ING + G D+ V
Sbjct 267 RRSDNINWGLNIQSSYRGVHVISEIKEGSPADACTKIDAGDEILMINGRTVVGWDLTSVV 326
Query 319 DLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHF------------DYDP 358
+ + +++ + +P K++ + +A DYDP
Sbjct 327 QQVGALDVLELSLIVKRRPREPQLPKQSKLAARALAPSSQTAKTYSTDDYDP 378
>sp|Q96JY6|PDLI2_HUMAN PDZ and LIM domain protein 2 OS=Homo sapiens
OX=9606 GN=PDLIM2 PE=1 SV=1
Length=352
Score = 45.4 bits (106), Expect = 0.001, Method: Composition-based stats.
Identities = 16/83 (19%), Positives = 29/83 (35%), Gaps = 2/83 (2%)
Query 266 PLGATVRNEMD-SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
T + ++++++ + G A+ + L GD ++ ING G E +
Sbjct 14 GFRITGGRDFHTPIMVTKVAERGKAKDAD-LRPGDIIVAINGESAEGMLHAEAQSKIRQS 72
Query 325 HGTLTFVLIPSQQIKPPPAKETV 347
L L SQ P
Sbjct 73 PSPLRLQLDRSQATSPGQTNGDS 95
>sp|Q6ZPF3|TIAM2_MOUSE Rho guanine nucleotide exchange factor
TIAM2 OS=Mus musculus OX=10090 GN=Tiam2 PE=1 SV=2
Length=1715
Score = 46.2 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 34/198 (17%), Positives = 70/198 (35%), Gaps = 16/198 (8%)
Query 184 SNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDERVY 243
+D+ V + + G +L +++ + ++ + EQ + VY
Sbjct 851 HRVEDVLALVCKMRQLEPTHYGLQLRKVVDKSVEWCVPALYEYMQEQVYDEIEVFPLSVY 910
Query 244 ESIGQYGGETVKIVRIEKARDIPLGATVRNEMD----SVIISRIVKGGAAEKSGLLHEGD 299
+ G+ D TV+ + + IS ++ A G L +G+
Sbjct 911 DVQLTKTGDM---------TDFGFAVTVQVDEHQHLNRIFISDVLPDSLAYG-GGLRKGN 960
Query 300 EVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKE--TVIHVKAHFDYD 357
E+ +NG + D+ ++ L S+ LT V P + A + + +
Sbjct 961 EITSLNGEPVSDLDIQQMEALFSEKSVGLTLVARPVTTRRTLCASWSDSDLFSRDQKSLP 1020
Query 358 PSDDPYVPCRELGLSFQK 375
PS + E +F+K
Sbjct 1021 PSPNQSQLLEEFLDNFRK 1038
>sp|Q9JJS5|SH3B4_RAT SH3 domain-binding protein 4 OS=Rattus norvegicus
OX=10116 GN=Sh3bp4 PE=1 SV=2
Length=961
Score = 46.2 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 31/160 (19%), Positives = 46/160 (29%), Gaps = 22/160 (14%)
Query 362 PYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQ 421
Y P L F KGD L+V+ WW A N G +P Q
Sbjct 65 DYCPNNFTTLKFSKGDHLYVLDTSGGEWWYA------HNTTEMGYIPSSYVQPLNY---- 114
Query 422 TIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRP 481
+ SG + + + K L D + Y ++ R P
Sbjct 115 ---RNSTLSDSGMIDNLPDSPDEVAKELDLLGGWTDDQKQSGRPYSNNPFWN--GVRTNP 169
Query 482 IILIG---PQNC---GQNELRQRLMNKEKDRFASAVPHTT 515
L G P ++ + L + F + TT
Sbjct 170 F-LNGNAQPSMDELNPKSTVDLLLFDTGTSSFTESSSATT 208
>sp|Q91VY6|CYTIP_MOUSE Cytohesin-interacting protein OS=Mus musculus
OX=10090 GN=Cytip PE=1 SV=1
Length=359
Score = 45.4 bits (106), Expect = 0.001, Method: Composition-based stats.
Identities = 25/115 (22%), Positives = 44/115 (38%), Gaps = 11/115 (10%)
Query 244 ESIGQYGGETVKIVRIEKARDIPLGA---TVRNEMDSV-------IISRIVKGGAAEKSG 293
S+G + K+V +EK + G T R + ++ +I ++ + A +G
Sbjct 65 SSLGDFSWSQRKVVTVEKQDNGTFGFEIQTYRLQNQNICSSEVCTMICKVQEDSPAHCAG 124
Query 294 LLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVI 348
L GD +NG+ G +V DL+ LT + I E +
Sbjct 125 -LQVGDIFANVNGVSTEGFTHKQVVDLIRSSGNLLTIETLNGTMIHRRAELEAKL 178
>sp|Q60592|MAST2_MOUSE Microtubule-associated serine/threonine-protein
kinase 2 OS=Mus musculus OX=10090 GN=Mast2 PE=1 SV=1
Length=1734
Score = 46.2 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 33/208 (16%), Positives = 71/208 (34%), Gaps = 12/208 (6%)
Query 165 IHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAH 224
H ++ + P+ + + ++L P H L + ++ PH Q+ +
Sbjct 965 RHRLLSGDSIEKRTTRPVNKVIKSASATALSLLIPSEHHACSPLASPMS-PHSQSSNPSS 1023
Query 225 DKVAEQEMQLEPI---TDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIIS 281
+ L + + G+ G T++ +R+ +G T + ++
Sbjct 1024 RDSSPSRDFLPALGSLRPPIIIHRAGKKYGFTLRAIRVY------MGDTDVYTVHH-MVW 1076
Query 282 RIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
+ GG A ++G L +GD + +NG + G EV +L+ ++ P +
Sbjct 1077 HVEDGGPASEAG-LRQGDLITHVNGEPVHGLVHTEVVELVLKSGNKVSISTTPLENTSIK 1135
Query 342 PAKETVIHVKAHFDYDPSDDPYVPCREL 369
KA +E
Sbjct 1136 VGPARKGSYKAKMARRSKRSKGKDGQES 1163
>sp|A1ZA47|ZASP_DROME PDZ and LIM domain protein Zasp OS=Drosophila
melanogaster OX=7227 GN=Zasp52 PE=1 SV=2
Length=2194
Score = 46.2 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 14/89 (16%), Positives = 36/89 (40%), Gaps = 3/89 (3%)
Query 254 VKIVRIEKARDIPLGATVRNEM-DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
+K+ R + A+ + +++ ++ G +E++G L GD V++IN +++
Sbjct 9 IKLSRFD-AQPWGFRLQGGTDFAQPLLVQKVNAGSLSEQAG-LQPGDAVVKINDVDVFNL 66
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
+ D++ + P
Sbjct 67 RHKDAQDIVVRSGNNFVITVQRGGSTWRP 95
>sp|Q8R5M0|GIPC3_MOUSE PDZ domain-containing protein GIPC3 OS=Mus
musculus OX=10090 GN=Gipc3 PE=1 SV=1
Length=297
Score = 45.0 bits (105), Expect = 0.001, Method: Composition-based stats.
Identities = 21/81 (26%), Positives = 33/81 (41%), Gaps = 2/81 (2%)
Query 254 VKIVRIEKARDIPLGATVRNEMDS-VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
K V + K + LG T+ + I RI +G + + GD + IN I G
Sbjct 95 TKEVEVTK-TEDALGLTITDNGAGYAFIKRIKEGSIINRIEAVCVGDSIEAINDHSIVGC 153
Query 313 DVNEVFDLLSDMHGTLTFVLI 333
EV +L ++ + F L
Sbjct 154 RHYEVAKMLRELPKSQPFTLR 174
>sp|Q9P864|SHO1_CYBJA High osmolarity signaling protein SHO1 OS=Cyberlindnera
jadinii OX=4903 GN=SHO1 PE=3 SV=1
Length=296
Score = 45.0 bits (105), Expect = 0.001, Method: Composition-based stats.
Identities = 18/63 (29%), Positives = 27/63 (43%), Gaps = 11/63 (17%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
+A ++Y S D E +SF+K +IL V + WWQA R G+ P
Sbjct 242 RALYNYQKSPDD-----ENEISFEKDEILKV-NDIHSRWWQAKR-----ANGEIGICPSN 290
Query 411 SFQ 413
+
Sbjct 291 YVE 293
>sp|Q6P0Q8|MAST2_HUMAN Microtubule-associated serine/threonine-protein
kinase 2 OS=Homo sapiens OX=9606 GN=MAST2 PE=1 SV=2
Length=1798
Score = 46.2 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 31/193 (16%), Positives = 68/193 (35%), Gaps = 16/193 (8%)
Query 165 IHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAH 224
H ++ + P+ + + ++L P H L + ++ PH Q+ +
Sbjct 1027 RHRLLSGDSTEKRTARPVNKVIKSASATALSLLIPSEHHTCSPLASPMS-PHSQSSNPSS 1085
Query 225 DKVAEQEMQLEP---ITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSV--I 279
+ L + + G+ G T++ +R+ ++ +V +
Sbjct 1086 RDSSPSRDFLPALGSMRPPIIIHRAGKKYGFTLRAIRVYMGDS---------DVYTVHHM 1136
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
+ + GG A ++G L +GD + +NG + G EV +L+ + P +
Sbjct 1137 VWHVEDGGPASEAG-LRQGDLITHVNGEPVHGLVHTEVVELILKSGNKVAISTTPLENTS 1195
Query 340 PPPAKETVIHVKA 352
KA
Sbjct 1196 IKVGPARKGSYKA 1208
>sp|B8R1V5|SHO1_CLALS High osmolarity signaling protein SHO1 OS=Clavispora
lusitaniae OX=36911 GN=SHO1 PE=3 SV=1
Length=299
Score = 45.0 bits (105), Expect = 0.001, Method: Composition-based stats.
Identities = 19/62 (31%), Positives = 24/62 (39%), Gaps = 11/62 (18%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
+A + YD S D +SF K +IL V D WWQA R G+ P
Sbjct 245 RALYSYDASPDDI-----NEISFVKDEILEV-DDIDGKWWQARR-----ANGQVGICPSN 293
Query 411 SF 412
Sbjct 294 YV 295
>sp|C4Y1G1|SHO1_CLAL4 High osmolarity signaling protein SHO1 OS=Clavispora
lusitaniae (strain ATCC 42720) OX=306902 GN=SHO1
PE=3 SV=1
Length=299
Score = 45.0 bits (105), Expect = 0.001, Method: Composition-based stats.
Identities = 19/62 (31%), Positives = 24/62 (39%), Gaps = 11/62 (18%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
+A + YD S D +SF K +IL V D WWQA R G+ P
Sbjct 245 RALYSYDASPDDI-----NEISFVKDEILEV-DDIDGKWWQARR-----ANGQVGICPSN 293
Query 411 SF 412
Sbjct 294 YV 295
>sp|O84709|DER_CHLTR GTPase Der OS=Chlamydia trachomatis (strain
D/UW-3/Cx) OX=272561 GN=der PE=3 SV=1
Length=490
Score = 45.4 bits (106), Expect = 0.001, Method: Composition-based stats.
Identities = 33/186 (18%), Positives = 66/186 (35%), Gaps = 23/186 (12%)
Query 406 LVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILT 465
+P S ++Q ++ED+ P + + + + + + + E L
Sbjct 162 QIPVPSVEEQ-----DAVQEDELPSEEAAISLHAFADETLFENESLSQEEASF--LEELV 214
Query 466 YEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRD--QEV 523
+ + P +R + LIG N G++ + L+ +E+ P TTR D
Sbjct 215 AQTATPA--PVDRPLKVALIGHPNVGKSSIINALLKEER-CITDNSPGTTRDNIDVAYTH 271
Query 524 AGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK 583
++Y F+ + +E S + I+ ICLL + + +
Sbjct 272 NNKEYVFIDTAGLRKTKSIKNSVEWM---------SSSRTEKAISRTDICLLVID--ATQ 320
Query 584 TLRNSD 589
L D
Sbjct 321 QLSYQD 326
>sp|Q3KKZ1|DER_CHLTA GTPase Der OS=Chlamydia trachomatis serovar
A (strain ATCC VR-571B / DSM 19440 / HAR-13) OX=315277 GN=der
PE=3 SV=1
Length=490
Score = 45.4 bits (106), Expect = 0.001, Method: Composition-based stats.
Identities = 33/186 (18%), Positives = 66/186 (35%), Gaps = 23/186 (12%)
Query 406 LVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILT 465
+P S ++Q ++ED+ P + + + + + + + E L
Sbjct 162 QIPVPSVEEQ-----DAVQEDELPSEEAAISLHAFADETLFENESLSQEEASF--LEELV 214
Query 466 YEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRD--QEV 523
+ + P +R + LIG N G++ + L+ +E+ P TTR D
Sbjct 215 AQTATPA--PVDRPLKVALIGHPNVGKSSIINALLKEER-CITDNSPGTTRDNIDVAYTH 271
Query 524 AGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK 583
++Y F+ + +E S + I+ ICLL + + +
Sbjct 272 NNKEYVFIDTAGLRKTKSIKNSVEWM---------SSSRTEKAISRTDICLLVID--ATQ 320
Query 584 TLRNSD 589
L D
Sbjct 321 QLSYQD 326
>sp|Q811L6|MAST4_MOUSE Microtubule-associated serine/threonine-protein
kinase 4 OS=Mus musculus OX=10090 GN=Mast4 PE=1 SV=3
Length=2618
Score = 46.2 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 16/68 (24%), Positives = 27/68 (40%), Gaps = 1/68 (1%)
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
I+ + +G A ++G L GD + ING + G EV +LL ++ P +
Sbjct 1171 IVWNVEEGSPAYQAG-LKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPFENT 1229
Query 339 KPPPAKET 346
Sbjct 1230 SIKTGPAR 1237
>sp|Q0SS84|RSGA_CLOPS Small ribosomal subunit biogenesis GTPase
RsgA OS=Clostridium perfringens (strain SM101 / Type A) OX=289380
GN=rsgA PE=3 SV=1
Length=287
Score = 45.0 bits (105), Expect = 0.001, Method: Composition-based stats.
Identities = 25/153 (16%), Positives = 47/153 (31%), Gaps = 46/153 (30%)
Query 483 ILIGPQNCGQNELRQRLMNKE-------KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+L GP G++ L +++E ++ HTTR +V + + V
Sbjct 158 VLCGPSGAGKSTLLNAFIDREHMETGSVSEKIGRGK-HTTRHSELIDVD--NGYLVDTPG 214
Query 536 FEAD----IAAGK----FIEHGEFEK-------NLYGTSIDSVRQVINSGKICLLSLRTQ 580
F I F E ++ N Y +V++ + GK
Sbjct 215 FTTLDVTFIDRDSLKYCFPEFNDYNNLCKFNGCNHYKEPKCAVKEAVEEGK--------- 265
Query 581 SLKTLRNSDLKPYIIFIAPPSQERLRALLAKEG 613
+ LR + L ++ + G
Sbjct 266 -INKLRYEFY-----------IKTLEEIINRRG 286
>sp|Q80U40|RIMB2_MOUSE RIMS-binding protein 2 OS=Mus musculus
OX=10090 GN=Rimbp2 PE=1 SV=3
Length=1072
Score = 45.8 bits (107), Expect = 0.001, Method: Composition-based stats.
Identities = 30/148 (20%), Positives = 55/148 (37%), Gaps = 9/148 (6%)
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVK---AHFDYD 357
++ N + D E+ D L + + + + + A +DYD
Sbjct 925 LIPCNMVSEIHADDEEMMDQLLRQGFLPLNTPVEKIERSRRSGRGHSVPTRRMVALYDYD 984
Query 358 PSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQRE 417
P + E L F GDI+ V + D + + G+ + Q GLVP ++ +
Sbjct 985 PRESSPNVDVEAELPFCTGDIITVFGEIDED---GFYYGELNGQK--GLVPSNFLEEVPD 1039
Query 418 AMKQTIEEDKEPEKSGKLWCAKKNKKKR 445
++ + D P S K K+K+
Sbjct 1040 DVEVHLS-DAPPHYSHDPPMRSKAKRKK 1066
Score = 35.8 bits (81), Expect = 1.5, Method: Composition-based stats.
Identities = 30/202 (15%), Positives = 68/202 (34%), Gaps = 36/202 (18%)
Query 352 AHFDYDP-SDDPYVPCRELGLSFQKGDILHVI-SQEDPNWWQAYREGDEDNQPL------ 403
A FDYDP + P E L F++G I+ V ++ +++ P
Sbjct 875 ALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEI 934
Query 404 -------------AGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLY 450
G +P + ++ E +++ P + ++ V
Sbjct 935 HADDEEMMDQLLRQGFLPLNTPVEKIERSRRSGRGHSVPTRRMVALYDYDPRESSPNVDV 994
Query 451 NANKNDDYDNEEILT----YEEMSLYHQPANRKRPIILIGPQN----CGQNELRQRLMNK 502
A + +I+T +E Y+ N ++ ++ P N + ++
Sbjct 995 EA--ELPFCTGDIITVFGEIDEDGFYYGELNGQKGLV---PSNFLEEVPDDVEVH--LSD 1047
Query 503 EKDRFASAVPHTTRSRRDQEVA 524
++ P ++++R + V
Sbjct 1048 APPHYSHDPPMRSKAKRKKSVH 1069
>sp|P23865|PRC_ECOLI Tail-specific protease OS=Escherichia coli
(strain K12) OX=83333 GN=prc PE=1 SV=2
Length=682
Score = 45.8 bits (107), Expect = 0.001, Method: Composition-based stats.
Identities = 29/159 (18%), Positives = 66/159 (42%), Gaps = 19/159 (12%)
Query 191 QEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHD----KVAEQEM--QLEPITDERVYE 244
E+ L KE +E I+ L + +A +++P T+
Sbjct 173 DELSLKLTGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPR 232
Query 245 SIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEI 304
+ Q+ E + +GA ++ + D +I+ +V GG A KS + GD+++ +
Sbjct 233 NTEQFNTEMSLSL-------EGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGV 285
Query 305 NG-----IEIRGKDVNEVFDLLSDMHGT-LTFVLIPSQQ 337
+++ G +++V L+ G+ + ++P+ +
Sbjct 286 GQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGK 324
>sp|Q1LVQ2|SH34A_DANRE SH3 domain-binding protein 4-A OS=Danio
rerio OX=7955 GN=sh3bp4a PE=2 SV=1
Length=965
Score = 45.8 bits (107), Expect = 0.001, Method: Composition-based stats.
Identities = 16/52 (31%), Positives = 19/52 (37%), Gaps = 6/52 (12%)
Query 362 PYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
Y P L F KGD L+V+ WW A N G +P Q
Sbjct 66 DYCPSSFTTLKFSKGDHLYVLDTSGGEWWYA------HNNREMGYIPSTYVQ 111
>sp|Q4P3H6|SLA1_USTMA Actin cytoskeleton-regulatory complex protein
SLA1 OS=Ustilago maydis (strain 521 / FGSC 9021) OX=237631
GN=SLA1 PE=3 SV=1
Length=1207
Score = 45.8 bits (107), Expect = 0.002, Method: Composition-based stats.
Identities = 22/94 (23%), Positives = 36/94 (38%), Gaps = 16/94 (17%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR---------EGDEDNQ 401
KA +DY V E L+ + D L+++ +DP WW+A D+ +
Sbjct 8 KALYDY-------VAQAEDELNLTEDDHLYILESDDPEWWKAKLRRLDEHGTPIQDDSDD 60
Query 402 PLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKL 435
GLVP ++ D E + +L
Sbjct 61 STVGLVPANYVEEAEPIRLSRALYDYEAQTEEEL 94
>sp|A0A142I732|PHOO2_DIALO ABC-type transporter phomO' OS=Diaporthe
leptostromiformis OX=291059 GN=phomO' PE=3 SV=1
Length=1561
Score = 45.8 bits (107), Expect = 0.002, Method: Composition-based stats.
Identities = 18/105 (17%), Positives = 50/105 (48%), Gaps = 11/105 (10%)
Query 406 LVPGKSFQ----QQREAMKQTIEEDKEPEKSGKLWCA-KKNKKKRKKVLYNANKNDDY-- 458
++P ++ +A + E E +++ + + + +K+K+ + + N +
Sbjct 593 IIPSFGAALGSLERIDAFFEKQEFTDERDEATAVDSSCSEKGEKKKEHVSLSIHNSSFSY 652
Query 459 -DNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNK 502
D+ E ++++L NR + +++ GP CG++ L Q ++ +
Sbjct 653 TDDSEDPILKDVNLV---INRGQHVVVTGPAGCGKSLLLQAILGE 694
>sp|F4KHG6|CTPA1_ARATH Carboxyl-terminal-processing peptidase
1, chloroplastic OS=Arabidopsis thaliana OX=3702 GN=CTPA1 PE=1
SV=1
Length=489
Score = 45.4 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 22/82 (27%), Positives = 39/82 (48%), Gaps = 7/82 (9%)
Query 258 RIEKARDIPLGATVRNEMDS-----VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 312
R+ K +G +R D + + +V AA+ +G + +GDE+L +NG+++ GK
Sbjct 191 RMSKYDITGIGINLREVSDGGGNVKLKVLGLVLDSAADIAG-VKQGDEILAVNGMDVSGK 249
Query 313 DVNEVFDLLSDMHGT-LTFVLI 333
EV LL T + +
Sbjct 250 SSFEVSSLLQGPSKTFVVLKVK 271
>sp|Q63ZR5|RHN2B_XENLA Rhophilin-2-B OS=Xenopus laevis OX=8355
GN=rhpn2-b PE=2 SV=1
Length=683
Score = 45.4 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 40/242 (17%), Positives = 81/242 (33%), Gaps = 31/242 (13%)
Query 124 IEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLI 183
I L+ S+ + Q+ +LL A + H +
Sbjct 381 ISQLYDSMPEGLTAQTILKDQQQRTLL----GKAHLSKAIRSHEEAIRFS--------TL 428
Query 184 SNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITD---- 239
+ +Q +L H + + + LL A D V++ E Q E I
Sbjct 429 CSTLRQIDVLQLILSAFHQRSLLKFSQHQKPDDFLDLLSAPDIVSKTEYQAETIPPQLSK 488
Query 240 ERVYESIGQYGGETV----------KIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAA 289
++V + + G ++ + + I K G ++ + +IS + A
Sbjct 489 DKVTDIFQRLGPLSIFSVKQRWSAPRKMCITKEDG-DFGFVLKGDCPVQVIS-LDPLCPA 546
Query 290 EKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG-TLTFVLIP-SQQIKPPPAKETV 347
G L EGD ++ + G + + ++V D+L + ++ +I Q K
Sbjct 547 ATEG-LKEGDYIVSVAGKDCKWCSTSQVMDMLQETGQDSIEIQVISIQDQTNSLANKSAT 605
Query 348 IH 349
+
Sbjct 606 YY 607
>sp|Q09666|AHNK_HUMAN Neuroblast differentiation-associated protein
AHNAK OS=Homo sapiens OX=9606 GN=AHNAK PE=1 SV=2
Length=5890
Score = 45.8 bits (107), Expect = 0.002, Method: Composition-based stats.
Identities = 19/78 (24%), Positives = 33/78 (42%), Gaps = 2/78 (3%)
Query 268 GATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMH-G 326
G T+ D V + + + A ++G++ EGD+++ I EV LL+ M
Sbjct 22 GLTIAQRDDGVFVQEVTQNSPAARTGVVKEGDQIVGA-TIYFDNLQSGEVTQLLNTMGHH 80
Query 327 TLTFVLIPSQQIKPPPAK 344
T+ L P P +
Sbjct 81 TVGLKLHRKGDRSPEPGQ 98
>sp|O60759|CYTIP_HUMAN Cytohesin-interacting protein OS=Homo sapiens
OX=9606 GN=CYTIP PE=1 SV=2
Length=359
Score = 45.0 bits (105), Expect = 0.002, Method: Composition-based stats.
Identities = 24/107 (22%), Positives = 40/107 (37%), Gaps = 11/107 (10%)
Query 254 VKIVRIEKARDIPLGATVRNEMDS----------VIISRIVKGGAAEKSGLLHEGDEVLE 303
K+V +EK + G +++ +I +I + A +G L GD +
Sbjct 75 RKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAG-LQAGDVLAN 133
Query 304 INGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHV 350
ING+ G +V DL+ LT + I E + V
Sbjct 134 INGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMILKRTELEAKLQV 180
>sp|Q9GKU1|PDLI2_MACFA PDZ and LIM domain protein 2 OS=Macaca
fascicularis OX=9541 GN=PDLIM2 PE=2 SV=1
Length=352
Score = 44.7 bits (104), Expect = 0.002, Method: Composition-based stats.
Identities = 16/83 (19%), Positives = 29/83 (35%), Gaps = 2/83 (2%)
Query 266 PLGATVRNEMD-SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
T + ++++++ + G A+ + L GD ++ ING G E +
Sbjct 14 GFRITGGRDFHTPIMVTKVAERGKAKDAD-LRPGDIIVAINGESAEGMLHAEAQSKIRQS 72
Query 325 HGTLTFVLIPSQQIKPPPAKETV 347
L L SQ P
Sbjct 73 PSPLRLQLDRSQAASPGQTNGDS 95
>sp|Q921I6|SH3B4_MOUSE SH3 domain-binding protein 4 OS=Mus musculus
OX=10090 GN=Sh3bp4 PE=1 SV=1
Length=962
Score = 45.4 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 32/161 (20%), Positives = 48/161 (30%), Gaps = 23/161 (14%)
Query 362 PYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQ 421
Y P L F KGD L+V+ WW A N G +P Q
Sbjct 65 DYCPNNFTTLKFSKGDHLYVLDTSGGEWWYA------HNTTEMGYIPSSYVQPLNY---- 114
Query 422 TIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEI-LTYEEMSLYHQPANRKR 480
+ SG + + ++ K L D +E Y ++ R
Sbjct 115 ---RNSTLSDSGMIDNLPDSPEEVAKELDLLGGGWTDDQKESGRPYSNNPFWN--GVRTN 169
Query 481 PIILIG---PQNC---GQNELRQRLMNKEKDRFASAVPHTT 515
P L G P ++ + L + F + TT
Sbjct 170 PF-LNGNAQPSTDELNPKSTVDLLLFDTGTSSFTESSSATT 209
>sp|Q32L23|LIMK2_BOVIN LIM domain kinase 2 OS=Bos taurus OX=9913
GN=LIMK2 PE=2 SV=1
Length=638
Score = 45.0 bits (105), Expect = 0.002, Method: Composition-based stats.
Identities = 23/107 (21%), Positives = 45/107 (42%), Gaps = 9/107 (8%)
Query 234 LEPITDERVYESIGQYGGETVKIVRI------EKARDIPLGATVRNEMDSVIISRI--VK 285
L P+ + ES+ +V + + + + + + N +V + + +
Sbjct 130 LAPMFERLSTESVQDQLPYSVTHISMPATTEGRRGFSVSVESACSNYATTVQVREVNRMH 189
Query 286 GGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
++ +H GD +LEING +R V EV D +S TL ++
Sbjct 190 ISPNNRN-AIHPGDRILEINGAPVRTLRVEEVEDAISQTTQTLQLLI 235
>sp|Q1W617|SHRM4_MOUSE Protein Shroom4 OS=Mus musculus OX=10090
GN=Shroom4 PE=1 SV=1
Length=1475
Score = 45.4 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 26/125 (21%), Positives = 53/125 (42%), Gaps = 11/125 (9%)
Query 257 VRIEKARDIPLGATVRNEMD---SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
V+++ P G T++ ++ + +S+I GG A S + GDE++ ING + G
Sbjct 13 VQLQGGA--PWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVNINGTPLYGSR 70
Query 314 VNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDP--SDDPYVPCRELGL 371
+ + G+ + + ++ P ++ HV + P + + P L
Sbjct 71 QEALILI----KGSFRILKLIVRRRNTPVSRPHSWHVAKLLEGCPDVATTMHFPSEAFSL 126
Query 372 SFQKG 376
S+ G
Sbjct 127 SWHSG 131
>sp|G5EDM4|NHRF1_CAEEL Na(+)/H(+) exchange regulatory cofactor-like
protein nrfl-1 OS=Caenorhabditis elegans OX=6239 GN=nrfl-1
PE=1 SV=1
Length=467
Score = 45.0 bits (105), Expect = 0.002, Method: Composition-based stats.
Identities = 13/68 (19%), Positives = 27/68 (40%), Gaps = 1/68 (1%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ + + AE+ G L GD + +NG I G++ +V + + ++
Sbjct 32 EKGRGQFVGTVDPDSPAER-GGLITGDRIFAVNGHSIIGENHKKVVERIKANPNRCEMLV 90
Query 333 IPSQQIKP 340
I + K
Sbjct 91 ISEEGAKW 98
>sp|O55043|ARHG7_RAT Rho guanine nucleotide exchange factor 7
OS=Rattus norvegicus OX=10116 GN=Arhgef7 PE=1 SV=1
Length=646
Score = 45.0 bits (105), Expect = 0.002, Method: Composition-based stats.
Identities = 18/72 (25%), Positives = 31/72 (43%), Gaps = 13/72 (18%)
Query 343 AKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQP 402
+ + V+A F++ ++ E LSF KGD++HV E+ WW+ G
Sbjct 4 NANSQLVVRAKFNFQQTN-------EDELSFSKGDVIHVTRVEEGGWWEGTHNG------ 50
Query 403 LAGLVPGKSFQQ 414
G P ++
Sbjct 51 RTGWFPSNYVRE 62
>sp|Q9P0V3|SH3B4_HUMAN SH3 domain-binding protein 4 OS=Homo sapiens
OX=9606 GN=SH3BP4 PE=1 SV=1
Length=963
Score = 45.4 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 16/52 (31%), Positives = 19/52 (37%), Gaps = 6/52 (12%)
Query 362 PYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
Y P L F KGD L+V+ WW A N G +P Q
Sbjct 65 DYCPTNFTTLKFSKGDHLYVLDTSGGEWWYA------HNTTEMGYIPSSYVQ 110
>sp|F1MSG6|RPGF2_BOVIN Rap guanine nucleotide exchange factor
2 OS=Bos taurus OX=9913 GN=RAPGEF2 PE=1 SV=2
Length=1486
Score = 45.4 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 16/83 (19%), Positives = 38/83 (46%), Gaps = 6/83 (7%)
Query 254 VKIVRIEK-ARDIPLGA---TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+++ + K AR+ PL + + + + A ++G L GD++LE+NG
Sbjct 383 RRLMTLTKPAREAPLPFILLGGSEKGFGIFVDSVDSASKATEAG-LKRGDQILEVNGQNF 441
Query 310 RGKDVNEVFDLLSDMHG-TLTFV 331
+++ ++L + ++T
Sbjct 442 ENIQLSKAMEILRNNTHLSITVK 464
>sp|O15021|MAST4_HUMAN Microtubule-associated serine/threonine-protein
kinase 4 OS=Homo sapiens OX=9606 GN=MAST4 PE=1 SV=4
Length=2623
Score = 45.4 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 16/68 (24%), Positives = 27/68 (40%), Gaps = 1/68 (1%)
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQI 338
I+ + +G A ++G L GD + ING + G EV +LL ++ P +
Sbjct 1173 IVWNVEEGSPACQAG-LKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPFENT 1231
Query 339 KPPPAKET 346
Sbjct 1232 SIKTGPAR 1239
>sp|O15034|RIMB2_HUMAN RIMS-binding protein 2 OS=Homo sapiens
OX=9606 GN=RIMBP2 PE=1 SV=3
Length=1052
Score = 45.0 bits (105), Expect = 0.002, Method: Composition-based stats.
Identities = 22/94 (23%), Positives = 40/94 (43%), Gaps = 5/94 (5%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A +DYDP + E L+F GDI+ V + D + + G+ + Q GLVP
Sbjct 959 ALYDYDPRESSPNVDVEAELTFCTGDIITVFGEIDED---GFYYGELNGQK--GLVPSNF 1013
Query 412 FQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKR 445
++ + ++ + + +K +KK
Sbjct 1014 LEEVPDDVEVYLSDAPSHYSQDTPMRSKAKRKKS 1047
Score = 34.6 bits (78), Expect = 4.3, Method: Composition-based stats.
Identities = 18/64 (28%), Positives = 28/64 (44%), Gaps = 6/64 (9%)
Query 352 AHFDYDP-SDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
A FDYDP + P E L F++G I+ V +D + + G+ GL+P
Sbjct 855 ALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDAD---GFYRGETCA--RLGLIPCN 909
Query 411 SFQQ 414
+
Sbjct 910 MVSE 913
>sp|A5DR93|SHO1_PICGU High osmolarity signaling protein SHO1 OS=Meyerozyma
guilliermondii (strain ATCC 6260 / CBS 566 / DSM
6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) OX=294746 GN=SHO1
PE=3 SV=2
Length=281
Score = 44.3 bits (103), Expect = 0.002, Method: Composition-based stats.
Identities = 26/111 (23%), Positives = 40/111 (36%), Gaps = 20/111 (18%)
Query 303 EINGIE-IRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDD 361
++NG+E DV + DL + T+ + + P + +A + Y
Sbjct 186 QLNGLENFSSADVRQSRDLTNSRRQTVI-----ADEEDAPVFRYKA---RALYSY----- 232
Query 362 PYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSF 412
P +SF K +IL V D WWQA R G+ P
Sbjct 233 SANPEDINEISFTKDEILDV-DDIDGKWWQARR-----ATGEVGICPSNYV 277
>sp|B0BAF8|DER_CHLTB GTPase Der OS=Chlamydia trachomatis serovar
L2b (strain UCH-1/proctitis) OX=471473 GN=der PE=3 SV=1
Length=490
Score = 44.7 bits (104), Expect = 0.002, Method: Composition-based stats.
Identities = 33/186 (18%), Positives = 66/186 (35%), Gaps = 23/186 (12%)
Query 406 LVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILT 465
+P S ++Q ++ED+ P + + + + + + + E L
Sbjct 162 QIPVPSVEEQ-----DVVQEDELPSEEAAISLHAFADETLFENESLSQEEASF--LEELV 214
Query 466 YEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRD--QEV 523
+ + P +R + LIG N G++ + L+ +E+ P TTR D
Sbjct 215 AQTATPA--PVDRPLKVALIGHPNVGKSSIINALLKEER-CITDNSPGTTRDNIDVAYTH 271
Query 524 AGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK 583
++Y F+ + +E S + I+ ICLL + + +
Sbjct 272 NNKEYVFIDTAGLRKTKSIKNSVEWM---------SSSRTEKAISRTDICLLVID--ATQ 320
Query 584 TLRNSD 589
L D
Sbjct 321 QLSYQD 326
>sp|B0B8S9|DER_CHLT2 GTPase Der OS=Chlamydia trachomatis serovar
L2 (strain 434/Bu / ATCC VR-902B) OX=471472 GN=der PE=3 SV=1
Length=490
Score = 44.7 bits (104), Expect = 0.002, Method: Composition-based stats.
Identities = 33/186 (18%), Positives = 66/186 (35%), Gaps = 23/186 (12%)
Query 406 LVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILT 465
+P S ++Q ++ED+ P + + + + + + + E L
Sbjct 162 QIPVPSVEEQ-----DVVQEDELPSEEAAISLHAFADETLFENESLSQEEASF--LEELV 214
Query 466 YEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRD--QEV 523
+ + P +R + LIG N G++ + L+ +E+ P TTR D
Sbjct 215 AQTATPA--PVDRPLKVALIGHPNVGKSSIINALLKEER-CITDNSPGTTRDNIDVAYTH 271
Query 524 AGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLK 583
++Y F+ + +E S + I+ ICLL + + +
Sbjct 272 NNKEYVFIDTAGLRKTKSIKNSVEWM---------SSSRTEKAISRTDICLLVID--ATQ 320
Query 584 TLRNSD 589
L D
Sbjct 321 QLSYQD 326
>sp|Q6CHN0|SLA1_YARLI Actin cytoskeleton-regulatory complex protein
SLA1 OS=Yarrowia lipolytica (strain CLIB 122 / E 150)
OX=284591 GN=SLA1 PE=3 SV=1
Length=1136
Score = 45.0 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 29/90 (32%), Positives = 36/90 (40%), Gaps = 15/90 (17%)
Query 322 SDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHV 381
+ GT L+P I+P PAK A +DYD E L+F++GD L V
Sbjct 48 AGPAGTNEIGLVPLTYIEPAPAKRQAY---ALYDYDKQ-------TEEELTFKEGDALTV 97
Query 382 ISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
D W R GDE G VP
Sbjct 98 YDDSDSEWLLVCRGGDEY-----GFVPANY 122
>sp|A8XI74|CED2_CAEBR Cell death abnormality protein 2 OS=Caenorhabditis
briggsae OX=6238 GN=ced-2 PE=3 SV=1
Length=277
Score = 43.9 bits (102), Expect = 0.003, Method: Composition-based stats.
Identities = 20/113 (18%), Positives = 41/113 (36%), Gaps = 8/113 (7%)
Query 367 RELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQ--REAMKQTIE 424
RE L F++G+ L ++S+ + +WW+A + GLVP Q Q A ++ +
Sbjct 128 RETDLPFEQGERLEILSKTNNDWWEAR-----NALGTTGLVPANYVQVQSGEFANERISK 182
Query 425 EDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPAN 477
+ A++ +T++ + + P
Sbjct 183 GTSQSSIGSSGNGAERFSSTSTSSENAEAHPTL-PTTAKVTFDRVPNAYDPTQ 234
>sp|G5EE56|SRC1_CAEEL Tyrosine protein-kinase src-1 OS=Caenorhabditis
elegans OX=6239 GN=src-1 PE=1 SV=1
Length=533
Score = 44.7 bits (104), Expect = 0.003, Method: Composition-based stats.
Identities = 19/84 (23%), Positives = 31/84 (37%), Gaps = 11/84 (13%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
A + YD D LSFQKGD ++++ + +WW + G VP
Sbjct 78 ALYPYDSRADGD-------LSFQKGDAMYLLDHSNCDWWYVRHQ----RTGQTGYVPRNF 126
Query 412 FQQQREAMKQTIEEDKEPEKSGKL 435
+Q+ + K P +
Sbjct 127 VAKQQTIESEEWYAGKIPRNRAER 150
>sp|A3LXQ8|HSE1_PICST Class E vacuolar protein-sorting machinery
protein HSE1 OS=Scheffersomyces stipitis (strain ATCC 58785
/ CBS 6054 / NBRC 10063 / NRRL Y-11545) OX=322104 GN=HSE1
PE=3 SV=2
Length=475
Score = 44.7 bits (104), Expect = 0.003, Method: Composition-based stats.
Identities = 33/168 (20%), Positives = 60/168 (36%), Gaps = 15/168 (9%)
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDM---HGTLTFVLIPSQQIKPPPAKETVIHVKAHFD 355
DE+ + + ++ + + L + Q K + V+A FD
Sbjct 171 DELQRVINLSLQEYEREQFSKSLQKPLPDPKKTSPRNANIAQEDSDDKKPEISKVRAMFD 230
Query 356 YDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQ 415
V + LSF+KGD+++VI +WW+ G+ P
Sbjct 231 -------LVSHEKDELSFRKGDLINVIEVVYRDWWRG-----SLPTGEVGIFPLNYVAPV 278
Query 416 REAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEI 463
IE++ + E +KK K + N N++ D+EE+
Sbjct 279 YAKSSDQIEKELQIENRLLNVESKKIDKVLAMLSAATNGNENIDDEEL 326
>sp|F1M386|RPGF2_RAT Rap guanine nucleotide exchange factor 2
OS=Rattus norvegicus OX=10116 GN=Rapgef2 PE=1 SV=2
Length=1496
Score = 45.0 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 14/76 (18%), Positives = 34/76 (45%), Gaps = 5/76 (7%)
Query 260 EKARDIPLGA---TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNE 316
+ +R+ PL + + + + A ++G L GD++LE+NG +++
Sbjct 390 KPSREAPLPFILLGGSEKGFGIFVDSVDSSSKATEAG-LKRGDQILEVNGQNFENIQLSK 448
Query 317 VFDLLSDMHG-TLTFV 331
++L + ++T
Sbjct 449 AMEILRNNTHLSITVK 464
>sp|Q895P5|RSGA_CLOTE Small ribosomal subunit biogenesis GTPase
RsgA OS=Clostridium tetani (strain Massachusetts / E88) OX=212717
GN=rsgA PE=3 SV=1
Length=290
Score = 43.9 bits (102), Expect = 0.003, Method: Composition-based stats.
Identities = 29/151 (19%), Positives = 52/151 (34%), Gaps = 26/151 (17%)
Query 445 RKKVLYNANKNDDYDNEEILTYEEMSLYH-QPANRKRPIILIGPQNCGQNELRQRLMNKE 503
K+ + + K+ Y+ + E M + + + +L GP G++ + +L+ K+
Sbjct 120 EKEEVVDIIKSAGYEVIYLNAKEGMGIEKIREKLKGNLNVLCGPSGAGKSTIINKLVGKD 179
Query 504 -------KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE----ADIAAGK----FIEH 548
++ HTTR EV D V F DI + F E
Sbjct 180 VMETGQISEKLKRGK-HTTRHSELIEVE--DGFLVDTPGFSSLSIEDIEKEEIQFLFPEF 236
Query 549 GEFEKNL-------YGTSIDSVRQVINSGKI 572
++ Y V+ + GKI
Sbjct 237 IKYINGCKFTGCLHYKEPSCVVKNALEQGKI 267
>sp|Q8FVV5|FBPC_BRUSU Fe(3+) ions import ATP-binding protein FbpC
OS=Brucella suis biovar 1 (strain 1330) OX=204722 GN=fbpC
PE=3 SV=1
Length=353
Score = 44.3 bits (103), Expect = 0.003, Method: Composition-based stats.
Identities = 27/219 (12%), Positives = 56/219 (26%), Gaps = 40/219 (18%)
Query 464 LTYEEMSL----------YHQPANRKRPIILIGPQNCGQNELRQRLMN-KEKDRFASAVP 512
+T+E ++ + L+GP CG+ + L + V
Sbjct 9 VTFENVTKKFGNFTALPNLSLTVEPGTLVTLLGPSGCGKTTTLRLLAGLEHPTSGRILVG 68
Query 513 HTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKI 572
+ F S F + +E+ + G + R+ G
Sbjct 69 GKDVTNLPANERDVSMVFQSYALFPHMTS----LENVAYGLESSGFKKNEARERAEEGLK 124
Query 573 CL--------LSLRTQSLKTLRNSDLKPYI----IFIAPPSQERLRALLAKEGKNPKPEE 620
+ L + R + + + + + L A L + + E
Sbjct 125 LVGLGGMGHRLPAELSGGQQQRVAVARALVLEPQVLLLDEPLSNLDARLRRRVRTEIREL 184
Query 621 LREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
+ + D D D+A +I
Sbjct 185 QQRLGFTA-----------DYVT--HDQDEALAVSDTII 210
>sp|Q6NU22|SH34A_XENLA SH3 domain-binding protein 4-A OS=Xenopus
laevis OX=8355 GN=sh3bp4-a PE=2 SV=1
Length=957
Score = 44.7 bits (104), Expect = 0.003, Method: Composition-based stats.
Identities = 31/113 (27%), Positives = 46/113 (41%), Gaps = 17/113 (15%)
Query 304 INGIEIRGKDVNEVFDLLSDMHGTLT-FVLI-PSQ-QIKPPPAKETVIHVKAHFDYDPSD 360
ING+ R K + D +L+ ++ PS +I P + E V V A DY P++
Sbjct 11 INGLP-RCKSEGTLIDFSGVPDPSLSEVKVLSPSSLRIDNPASLENVKEVVAIKDYCPNN 69
Query 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
L F KG+ L+V+ +WW A N G +P Q
Sbjct 70 -------FTTLKFSKGEHLYVLDASGGDWWYA------HNSTEMGYIPSSYVQ 109
>sp|Q09822|CDC15_SCHPO Cell division control protein 15 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=cdc15
PE=1 SV=2
Length=927
Score = 44.7 bits (104), Expect = 0.003, Method: Composition-based stats.
Identities = 18/65 (28%), Positives = 27/65 (42%), Gaps = 9/65 (14%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+V A +DY + SFQKGD L V+ ++ WW +++ GL P
Sbjct 870 YVIALYDYQAQIPEEI-------SFQKGDTLMVLRTQEDGWWDGEIINVPNSK--RGLFP 920
Query 409 GKSFQ 413
Q
Sbjct 921 SNFVQ 925
>sp|Q8CHG7|RPGF2_MOUSE Rap guanine nucleotide exchange factor
2 OS=Mus musculus OX=10090 GN=Rapgef2 PE=1 SV=2
Length=1496
Score = 44.7 bits (104), Expect = 0.003, Method: Composition-based stats.
Identities = 15/83 (18%), Positives = 38/83 (46%), Gaps = 6/83 (7%)
Query 254 VKIVRIEK-ARDIPLGA---TVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEI 309
+++ + K +R+ PL + + + + A ++G L GD++LE+NG
Sbjct 383 RRLMTLTKPSREAPLPFILLGGSEKGFGIFVDSVDSCSKATEAG-LKRGDQILEVNGQNF 441
Query 310 RGKDVNEVFDLLSDMHG-TLTFV 331
+++ ++L + ++T
Sbjct 442 ENIQLSKAMEILRNNTHLSITVK 464
>sp|Q9QWY8|ASAP1_MOUSE Arf-GAP with SH3 domain, ANK repeat and
PH domain-containing protein 1 OS=Mus musculus OX=10090 GN=Asap1
PE=1 SV=2
Length=1147
Score = 44.7 bits (104), Expect = 0.003, Method: Composition-based stats.
Identities = 44/221 (20%), Positives = 83/221 (38%), Gaps = 25/221 (11%)
Query 197 LKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEM--QLEPITDERVYESIGQYGGETV 254
+ P ++ +LT L P + L ++A + +L P E +
Sbjct 934 IPPETFQKSSQLTELPQKPPLGELPPKPVELAPKPQVGELPPKPGELPPKPQLGDLPPKP 993
Query 255 KIVRIE---KARDIP----LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
++ + + +D+P LG + + +++ +E + H GD L N
Sbjct 994 QLSDLPPKPQMKDLPPKPQLGDLLAKSQAGDVSAKVQP--PSEVTQRSHTGD--LSPNVQ 1049
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCR 367
R + + +D+ TL +P + K K V VK +D +D
Sbjct 1050 S-RDAIQKQASEDSNDLTPTLPETPVPLPR-KINTGKNKVRRVKTIYDCQADNDDE---- 1103
Query 368 ELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
L+F +G+++ V +ED WW + EG G+ P
Sbjct 1104 ---LTFIEGEVIIVTGEEDQEWWIGHIEGQP---ERKGVFP 1138
>sp|Q5A895|HSE1_CANAL Class E vacuolar protein-sorting machinery
protein HSE1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876)
OX=237561 GN=HSE1 PE=3 SV=1
Length=498
Score = 44.3 bits (103), Expect = 0.003, Method: Composition-based stats.
Identities = 21/84 (25%), Positives = 33/84 (39%), Gaps = 18/84 (21%)
Query 332 LIPSQQIKPPPAKETVIHVKAHFD---YDPSDDPYVPCRELGLSFQKGDILHVISQEDPN 388
+ P + P TV V+A +D Y+P + LSF+KGD++ VI +
Sbjct 199 IQPEPESPPVETVATVSKVRALYDLVSYEPDE----------LSFRKGDVITVIESVYRD 248
Query 389 WWQAYREGDEDNQPLAGLVPGKSF 412
WW+ G+ P
Sbjct 249 WWRG-----SLPSGKIGIFPLNYV 267
>sp|P70248|MYO1F_MOUSE Unconventional myosin-If OS=Mus musculus
OX=10090 GN=Myo1f PE=1 SV=1
Length=1099
Score = 44.7 bits (104), Expect = 0.003, Method: Composition-based stats.
Identities = 18/82 (22%), Positives = 33/82 (40%), Gaps = 14/82 (17%)
Query 333 IPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 392
+P+ + KP P +A + Y D LSF +++ ++ ++ WW+
Sbjct 1031 VPASRPKPQPRTHGP-RCRALYQYIGQDVDE-------LSFNVNEVIEILIEDSSGWWKG 1082
Query 393 YREGDEDNQPLAGLVPGKSFQQ 414
G E GL PG ++
Sbjct 1083 RLHGQE------GLFPGNYVEK 1098
>sp|Q9JIR0|RIMB1_RAT Peripheral-type benzodiazepine receptor-associated
protein 1 OS=Rattus norvegicus OX=10116 GN=Tspoap1
PE=1 SV=2
Length=1847
Score = 44.7 bits (104), Expect = 0.003, Method: Composition-based stats.
Identities = 31/191 (16%), Positives = 62/191 (32%), Gaps = 20/191 (10%)
Query 237 ITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNE--MDSVIISRIVKGGAAEKSGL 294
+ E + G+ +K+ + A G + + +++ + + L
Sbjct 1635 PNPDAGEEELPFREGQILKVFGDKDADGFYRGESGGRTGYIPCNMVAEVAVDTPTGRQQL 1694
Query 295 LHEGDEVLEI------NGIEIRGKDVNEVFDLLSDMHGTLTF----VLIPSQ-QIKPPPA 343
L G + NG + + L P ++ A
Sbjct 1695 LQRGFLPPNVLTQGSGNGPSVYPSAHTPGPPPKPRRSKKVELEDPAQLCPGPPKLIHSAA 1754
Query 344 KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVI-SQEDPNWWQAYREGDEDNQP 402
+T + A FDY+P ++ E L F+ GD++ V + +D ++ G
Sbjct 1755 LKTSRPMVAAFDYNPRENSPNMDVEAELPFRAGDVITVFGNMDDDGFYYGELNG------ 1808
Query 403 LAGLVPGKSFQ 413
GLVP +
Sbjct 1809 QRGLVPSNFLE 1819
Score = 41.6 bits (96), Expect = 0.027, Method: Composition-based stats.
Identities = 24/90 (27%), Positives = 37/90 (41%), Gaps = 10/90 (11%)
Query 329 TFVLIPSQQIKPPPAKET---VIHVKAHFDYDP-SDDPYVPCRELGLSFQKGDILHVISQ 384
T L P + + P+ + + V A FDYDP S P E L F++G IL V
Sbjct 1599 TTELAPPRSPQEAPSHQDLPLRVFV-ALFDYDPISMSPNPDAGEEELPFREGQILKVFGD 1657
Query 385 EDPNWWQAYREGDEDNQPLAGLVPGKSFQQ 414
+D + + G+ G +P +
Sbjct 1658 KDAD---GFYRGESGG--RTGYIPCNMVAE 1682
>sp|Q75JD4|Y1676_DICDI SH3 and F-BAR domain-containing protein
DDB_G0271676 OS=Dictyostelium discoideum OX=44689 GN=DDB_G0271676
PE=4 SV=1
Length=533
Score = 44.3 bits (103), Expect = 0.003, Method: Composition-based stats.
Identities = 13/61 (21%), Positives = 28/61 (46%), Gaps = 10/61 (16%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
V+A +DY+ +++ + SF+ ++ V+ +++ WWQ G G+ P
Sbjct 411 VRALYDYNATEENEI-------SFKANALIKVVLRDESGWWQGMVIG---ESDRIGVFPS 460
Query 410 K 410
Sbjct 461 N 461
>sp|P41239|CSK_CHICK Tyrosine-protein kinase CSK OS=Gallus gallus
OX=9031 GN=CSK PE=2 SV=1
Length=450
Score = 44.3 bits (103), Expect = 0.003, Method: Composition-based stats.
Identities = 15/50 (30%), Positives = 27/50 (54%), Gaps = 6/50 (12%)
Query 368 ELGLSFQKGDILHVIS-QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQR 416
E L F KGD+L +++ +DPNW++A + G++P Q++
Sbjct 25 EQDLPFSKGDVLTIVAVTKDPNWYKAK-----NKVGREGIIPANYVQKRE 69
>sp|P73940|HHOB_SYNY3 Putative serine protease HhoB OS=Synechocystis
sp. (strain PCC 6803 / Kazusa) OX=1111708 GN=hhoB PE=1
SV=1
Length=416
Score = 44.3 bits (103), Expect = 0.003, Method: Composition-based stats.
Identities = 17/91 (19%), Positives = 39/91 (43%), Gaps = 4/91 (4%)
Query 258 RIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
++ + ++P G T V+I ++ G A ++G L GD +LE+ G+ ++ +
Sbjct 324 QLRTSGELPAGVTAD---TGVLIIQVSPGSPAAQAG-LAPGDIILEVGGMGVKTATDVQE 379
Query 318 FDLLSDMHGTLTFVLIPSQQIKPPPAKETVI 348
+S + L + Q+ + +
Sbjct 380 RVEVSQIGEPLAIAVKRGQKPQMMAVRPGPF 410
>sp|Q9D9M4|PDZD9_MOUSE PDZ domain-containing protein 9 OS=Mus
musculus OX=10090 GN=Pdzd9 PE=1 SV=2
Length=266
Score = 43.5 bits (101), Expect = 0.004, Method: Composition-based stats.
Identities = 17/85 (20%), Positives = 34/85 (40%), Gaps = 0/85 (0%)
Query 265 IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
+ LG V + IS ++ GAA G+L GD ++ + + G + E LL ++
Sbjct 38 LGLGLVVIQNGPYLQISHLINKGAAASDGILQPGDVLISVGHANVLGYTLREFLKLLQNI 97
Query 325 HGTLTFVLIPSQQIKPPPAKETVIH 349
+ + P + ++
Sbjct 98 TIGTVLQIKAYRGFLEIPQEWQDVY 122
>sp|Q32KW7|PDZD9_BOVIN PDZ domain-containing protein 9 OS=Bos
taurus OX=9913 GN=PDZD9 PE=2 SV=1
Length=263
Score = 43.5 bits (101), Expect = 0.004, Method: Composition-based stats.
Identities = 17/86 (20%), Positives = 33/86 (38%), Gaps = 0/86 (0%)
Query 264 DIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD 323
+ LG + + IS ++ GAA + G L GD ++ + + G + E LL
Sbjct 37 SMGLGLIIIQHGPYLQISHLITKGAAARDGTLQPGDVLISVGYANVLGYTLREFLKLLQH 96
Query 324 MHGTLTFVLIPSQQIKPPPAKETVIH 349
+ + + P + I+
Sbjct 97 ITIGTILQIKVYRDFIDIPQEWQEIY 122
>sp|P06239|LCK_HUMAN Tyrosine-protein kinase Lck OS=Homo sapiens
OX=9606 GN=LCK PE=1 SV=6
Length=509
Score = 44.3 bits (103), Expect = 0.004, Method: Composition-based stats.
Identities = 54/320 (17%), Positives = 104/320 (33%), Gaps = 61/320 (19%)
Query 320 LLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDIL 379
LL + L+ + PP + V A Y+PS D L F+KG+ L
Sbjct 36 LLIRNGSEVRDPLVTYEGSNPPASPLQDNLVIALHSYEPSHDGD-------LGFEKGEQL 88
Query 380 HVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ-----------QREAMKQTIEEDKE 428
++ Q WW+A G +P + + + K +
Sbjct 89 RILEQS-GEWWKA----QSLTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLA 143
Query 429 PEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQ 488
P + + + + + ++ D + E++ + ++ P I
Sbjct 144 PGNTHGSF-LIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITF--- 199
Query 489 NCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE--ADIAAGKFI 546
G +EL + D + + ++++ Q+ D V R+ + + AG+F
Sbjct 200 -PGLHELVRH-YTNASDGLCTRLSRPCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQF- 256
Query 547 EHGEFEKNLY-GTSIDSVRQVINSGK---ICLLSLRTQSLKTLRNSDL---------KPY 593
GE Y G + +V+ + G L +K L++ L +P
Sbjct 257 --GEVWMGYYNGHTKVAVKS-LKQGSMSPDAFL-AEANLMKQLQHQRLVRLYAVVTQEPI 312
Query 594 II------------FIAPPS 601
I F+ PS
Sbjct 313 YIITEYMENGSLVDFLKTPS 332
>sp|Q7SGL6|SHO1_NEUCR High osmolarity signaling protein sho1 OS=Neurospora
crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71
/ DSM 1257 / FGSC 987) OX=367110 GN=sho1 PE=3 SV=2
Length=322
Score = 43.5 bits (101), Expect = 0.004, Method: Composition-based stats.
Identities = 20/80 (25%), Positives = 30/80 (38%), Gaps = 11/80 (14%)
Query 333 IPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 392
P + + P E KA F Y+ + D +SF K ++L + WWQA
Sbjct 251 KPQGEGEIVPPTEYPYRAKAIFSYEANPDDA-----NEISFSKHEVLEISDVS-GRWWQA 304
Query 393 YREGDEDNQPLAGLVPGKSF 412
+E E G+ P
Sbjct 305 RKENGE-----TGIAPSNYL 319
>sp|Q8XJL9|RSGA_CLOPE Small ribosomal subunit biogenesis GTPase
RsgA OS=Clostridium perfringens (strain 13 / Type A) OX=195102
GN=rsgA PE=3 SV=1
Length=287
Score = 43.5 bits (101), Expect = 0.004, Method: Composition-based stats.
Identities = 25/153 (16%), Positives = 47/153 (31%), Gaps = 46/153 (30%)
Query 483 ILIGPQNCGQNELRQRLMNKE-------KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+L GP G++ L +++E ++ HTTR +V + + V
Sbjct 158 VLCGPSGAGKSTLLNSFIDREHMETGSVSEKIGRGK-HTTRHSELIDVD--NGYLVDTPG 214
Query 536 FEAD----IAAGK----FIEHGEFEK-------NLYGTSIDSVRQVINSGKICLLSLRTQ 580
F I F E ++ N Y +V++ + GK
Sbjct 215 FTTLDVTFIDRDSLKYCFPEFNDYNNLCKFNGCNHYKEPKCAVKEAVEEGK--------- 265
Query 581 SLKTLRNSDLKPYIIFIAPPSQERLRALLAKEG 613
+ LR + L ++ + G
Sbjct 266 -INKLRYEFY-----------IKTLEEIINRRG 286
>sp|Q13882|PTK6_HUMAN Protein-tyrosine kinase 6 OS=Homo sapiens
OX=9606 GN=PTK6 PE=1 SV=1
Length=451
Score = 43.9 bits (102), Expect = 0.004, Method: Composition-based stats.
Identities = 14/49 (29%), Positives = 21/49 (43%), Gaps = 1/49 (2%)
Query 368 ELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQR 416
+ LSF+ GD+ HV +E WW A + G VP ++
Sbjct 24 DEELSFRAGDVFHVARKE-EQWWWATLLDEAGGAVAQGYVPHNYLAERE 71
>sp|Q12965|MYO1E_HUMAN Unconventional myosin-Ie OS=Homo sapiens
OX=9606 GN=MYO1E PE=1 SV=2
Length=1108
Score = 44.3 bits (103), Expect = 0.004, Method: Composition-based stats.
Identities = 17/64 (27%), Positives = 23/64 (36%), Gaps = 13/64 (20%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
KA + YD D LSF DI+ +I ++ WW G GL P
Sbjct 1057 KALYAYDAQDTDE-------LSFNANDIIDIIKEDPSGWWTGRLRGK------QGLFPNN 1103
Query 411 SFQQ 414
+
Sbjct 1104 YVTK 1107
>sp|Q97B38|KAD6_THEVO Putative adenylate kinase OS=Thermoplasma
volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC
15438 / GSS1) OX=273116 GN=TV0621 PE=3 SV=1
Length=153
Score = 42.0 bits (97), Expect = 0.004, Method: Composition-based stats.
Identities = 24/201 (12%), Positives = 60/201 (30%), Gaps = 66/201 (33%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDY--HF---VSR 533
+ + GP G++ + +L + ++ ++Y F V
Sbjct 2 GKIACITGPPGAGKSTVCSKLRE-----YGYNC-------KEGNELAKEYGCLFDEEVDV 49
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ E +A +F G IC + + L
Sbjct 50 ECLEEKLAEDRF-----------------------DGIIC----------SHYSHLLGCS 76
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFD----------TAI 643
+FI L + G + + I++ E + ++ Y++ +
Sbjct 77 TVFILEADLNDLIDRMRARGYSEEK------IQENIETQMSSIFYYESLERLPANRIFTL 130
Query 644 VNSDLDKAYQELLRLINKLDT 664
N ++D+ + ++ +I +
Sbjct 131 YNGNIDETAKRIISIIERSRN 151
>sp|E3QNZ1|SHO1_COLGM High osmolarity signaling protein SHO1 OS=Colletotrichum
graminicola (strain M1.001 / M2 / FGSC 10212)
OX=645133 GN=SHO1 PE=3 SV=1
Length=293
Score = 43.5 bits (101), Expect = 0.004, Method: Composition-based stats.
Identities = 25/110 (23%), Positives = 38/110 (35%), Gaps = 13/110 (12%)
Query 305 NGIEIRGKDVNEVFDLLSDMHGTLT--FVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDP 362
N ++G + + + T P Q + P E KA + Y+ + D
Sbjct 192 NPSPVQGISTTQARNSVVAPTFNATPPATKGPGQDQEVVPPTEYPYRAKAIYSYEANPDD 251
Query 363 YVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSF 412
+SF K +IL V WWQA +E E G+ P
Sbjct 252 A-----NEISFSKHEILEVSDVS-GRWWQARKETGE-----TGIAPSNYL 290
>sp|Q9ULD6|INTU_HUMAN Protein inturned OS=Homo sapiens OX=9606
GN=INTU PE=1 SV=2
Length=942
Score = 44.3 bits (103), Expect = 0.004, Method: Composition-based stats.
Identities = 11/75 (15%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ + +++ ++ GG+A KSG + GD ++ +N +++ +++ V + +
Sbjct 203 GDGERLVVHGLLPGGSAMKSGQVLIGDVLVAVNDVDVTTENIERVLSCIPGPMQ-VKLTF 261
Query 333 IPSQQIKPPPAKETV 347
+ +K +
Sbjct 262 ENAYDVKRETSHPRQ 276
>sp|B1V8A0|SH3GH_CAEEL Endophilin-A homolog OS=Caenorhabditis
elegans OX=6239 GN=unc-57 PE=1 SV=1
Length=381
Score = 43.5 bits (101), Expect = 0.004, Method: Composition-based stats.
Identities = 27/109 (25%), Positives = 43/109 (39%), Gaps = 17/109 (16%)
Query 311 GKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPP------AKETVIHVKAHFDYDPSDDPYV 364
F + G +T PS Q PP +++ +A FD+D
Sbjct 281 NSTAAAAFKMPPQNGGGIT-QAPPSYQGPPPGGLPPPLSQQQKPQCRALFDFDAQ----- 334
Query 365 PCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAG---LVPGK 410
E L F++G ++ ++SQ D NW++ G P+ LVP K
Sbjct 335 --SEGELDFKEGTLIELVSQIDENWYEGRVNGKTGLFPVTYVQVLVPLK 381
>sp|Q0TPL7|RSGA_CLOP1 Small ribosomal subunit biogenesis GTPase
RsgA OS=Clostridium perfringens (strain ATCC 13124 / DSM 756
/ JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) OX=195103 GN=rsgA
PE=3 SV=1
Length=287
Score = 43.1 bits (100), Expect = 0.004, Method: Composition-based stats.
Identities = 25/153 (16%), Positives = 47/153 (31%), Gaps = 46/153 (30%)
Query 483 ILIGPQNCGQNELRQRLMNKE-------KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
+L GP G++ L +++E ++ HTTR +V + + V
Sbjct 158 VLCGPSGAGKSTLLNSFIDREHMETGSVSEKIGRGK-HTTRHSELIDVD--NGYLVDTPG 214
Query 536 FEAD----IAAGK----FIEHGEFEK-------NLYGTSIDSVRQVINSGKICLLSLRTQ 580
F I F E ++ N Y +V++ + GK
Sbjct 215 FTTLDVTFIDRDSLKYCFPEFNDYNNLCKFNGCNHYKEPKCAVKEAVEEGK--------- 265
Query 581 SLKTLRNSDLKPYIIFIAPPSQERLRALLAKEG 613
+ LR + L ++ + G
Sbjct 266 -INKLRYDFY-----------IKTLEEIINRRG 286
>sp|C9SA05|SHO1_VERA1 High osmolarity signaling protein SHO1 OS=Verticillium
alfalfae (strain VaMs.102 / ATCC MYA-4576 / FGSC
10136) OX=526221 GN=SHO1 PE=3 SV=1
Length=293
Score = 43.1 bits (100), Expect = 0.005, Method: Composition-based stats.
Identities = 26/109 (24%), Positives = 37/109 (34%), Gaps = 12/109 (11%)
Query 304 INGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPY 363
+ GI N L+ T P Q + P E KA + Y+ +
Sbjct 194 VGGISQSQAPRNSAVPNLNSTGVTANGK-PPGQDQEVGPPTEYPYRAKAIYSYEAN---- 248
Query 364 VPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSF 412
P +SF K +IL V WWQA +E + G+ P
Sbjct 249 -PEDANEISFSKHEILEVSDVS-GRWWQARKESGD-----TGIAPSNYL 290
>sp|F4J3G5|CTPA3_ARATH Carboxyl-terminal-processing peptidase
3, chloroplastic OS=Arabidopsis thaliana OX=3702 GN=CTPA3 PE=3
SV=1
Length=519
Score = 43.9 bits (102), Expect = 0.005, Method: Composition-based stats.
Identities = 19/72 (26%), Positives = 35/72 (49%), Gaps = 2/72 (3%)
Query 263 RDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
+ + L +++ V+G A+++G +HEG+E++EING ++ D L
Sbjct 198 QGVGLFINSEPRTGHLVVMSCVEGSPADRAG-IHEGEELVEINGEKLDDVDSEAAAQKLR 256
Query 323 DMHGT-LTFVLI 333
GT +T L
Sbjct 257 GRVGTFVTIKLK 268
>sp|Q810W7|MAST1_RAT Microtubule-associated serine/threonine-protein
kinase 1 OS=Rattus norvegicus OX=10116 GN=Mast1 PE=1
SV=1
Length=1570
Score = 44.3 bits (103), Expect = 0.005, Method: Composition-based stats.
Identities = 24/100 (24%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP--SQ 336
I+ + +GG A+++G L GD + +NG + G EV +L+ + P +
Sbjct 1001 IVWHVEEGGPAQEAG-LCAGDLITHVNGEPVHGMVHPEVVELILKSGNKVAVTTTPFENT 1059
Query 337 QIKPPPAKETVIHVK-AHFDYDPSDDPYVPCRELGLSFQK 375
I+ PA+ + K A + PS ++ F+K
Sbjct 1060 SIRIGPARRSSYKAKMARRNKRPSAKDGQESKKRSSLFRK 1099
>sp|Q9R1L5|MAST1_MOUSE Microtubule-associated serine/threonine-protein
kinase 1 OS=Mus musculus OX=10090 GN=Mast1 PE=1 SV=3
Length=1570
Score = 44.3 bits (103), Expect = 0.005, Method: Composition-based stats.
Identities = 24/100 (24%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP--SQ 336
I+ + +GG A+++G L GD + +NG + G EV +L+ + P +
Sbjct 1001 IVWHVEEGGPAQEAG-LCAGDLITHVNGEPVHGMVHPEVVELILKSGNKVAVTTTPFENT 1059
Query 337 QIKPPPAKETVIHVK-AHFDYDPSDDPYVPCRELGLSFQK 375
I+ PA+ + K A + PS ++ F+K
Sbjct 1060 SIRIGPARRSSYKAKMARRNKRPSAKDGQESKKRSSLFRK 1099
>sp|Q3T0C8|PDLI2_BOVIN PDZ and LIM domain protein 2 OS=Bos taurus
OX=9913 GN=PDLIM2 PE=2 SV=1
Length=348
Score = 43.5 bits (101), Expect = 0.005, Method: Composition-based stats.
Identities = 22/121 (18%), Positives = 40/121 (33%), Gaps = 13/121 (11%)
Query 257 VRIEKARDIPLGATVRNEMD-SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVN 315
V + + + ++++++ + G AE + L GD ++ ING +
Sbjct 5 VDVVGPAPWGFRISGGRDFHTPIMVTKVTERGKAEAAD-LRPGDIIVSINGESAKDMLHA 63
Query 316 EVFDLLSDMHGTLTFVL-IPSQQIKPPPAKETVIHV---------KAHFDYDPSDDPYVP 365
E + L L P E+ + V + H D S P P
Sbjct 64 EAQSKIRQSPSPLRLQLDRPQAASPGQANGESSLEVLATRFQSSRRTHTDSQASLSPR-P 122
Query 366 C 366
C
Sbjct 123 C 123
>sp|Q62420|SH3G2_MOUSE Endophilin-A1 OS=Mus musculus OX=10090
GN=Sh3gl2 PE=1 SV=2
Length=352
Score = 43.5 bits (101), Expect = 0.005, Method: Composition-based stats.
Identities = 18/69 (26%), Positives = 33/69 (48%), Gaps = 7/69 (10%)
Query 338 IKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGD 397
KPP + +A +D++P + E L F++GDI+ + +Q D NW++ G
Sbjct 283 PKPPGVQMDQPCCRALYDFEPEN-------EGELGFKEGDIITLTNQIDENWYEGMLHGQ 335
Query 398 EDNQPLAGL 406
P+ +
Sbjct 336 SGFFPINYV 344
>sp|Q498M5|SH3R2_RAT E3 ubiquitin-protein ligase SH3RF2 OS=Rattus
norvegicus OX=10116 GN=Sh3rf2 PE=1 SV=1
Length=735
Score = 43.9 bits (102), Expect = 0.005, Method: Composition-based stats.
Identities = 53/287 (18%), Positives = 96/287 (33%), Gaps = 60/287 (21%)
Query 240 ERVYESIGQYGGETVKIVRI------EKARDIP---------LGATVRNEMDSVIISRIV 284
+ V + G + + RI KA+ P LG TVR MD V ++ +
Sbjct 74 DGVRSGHNSWRGGSFRRPRILTLQDNRKAKSSPRSLQASPFRLGPTVRIHMDGVPRAKAL 133
Query 285 KGGAAEKSGLLH--EGDEVL------------EINGIEIRGKDVNEVFDLLSDMHGTLTF 330
+ G L +GD +L EING+ G +++ +
Sbjct 134 CNYRGKNPGDLKFNKGDVILLQRQLDENWYQGEINGVS--GFFPASSVEVIKQLP----- 186
Query 331 VLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW 390
+PPP +A +++D D ++ L+F K D++ VIS+ D NW
Sbjct 187 --------QPPPL------CRALYNFDLRDKDKSENQDC-LTFLKDDVITVISRVDENWA 231
Query 391 QAYREGDEDNQPLAGLVPG---KSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKK 447
+ P+ + P + ++ + + + + S A RK
Sbjct 232 EGKLGDKVGIFPILFVEPNLSARHLLEKSKGHQLSRTKHLSLMSSPSRGKATNTSTLRKS 291
Query 448 VLYNANKNDDYD-NEEILTYEEMSLY---HQPANRKRPIILI--GPQ 488
+ + + T M HQ P+++ P
Sbjct 292 PGSRRKGSGQFAMTTALNTLNRMVHSPEGHQMVEISTPVLISSTSPS 338
>sp|Q6AX33|MAST3_XENLA Microtubule-associated serine/threonine-protein
kinase 3 OS=Xenopus laevis OX=8355 GN=mast3 PE=2 SV=1
Length=1482
Score = 43.9 bits (102), Expect = 0.005, Method: Composition-based stats.
Identities = 23/116 (20%), Positives = 49/116 (42%), Gaps = 10/116 (9%)
Query 234 LEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSG 293
+ + + S G+ G T++ +R+ +G + + ++ + G A ++G
Sbjct 964 VSSLRPPIIIHSSGKKYGFTLRAIRVY------MGESDVYTVHH-MVWNVEDGSPAHEAG 1016
Query 294 LLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP--SQQIKPPPAKETV 347
L GD + +NG + G +V +LL ++ P + IK PA++
Sbjct 1017 -LRAGDLITHVNGESVLGLVHMDVVELLLKSGSKVSLRTTPLENTSIKIGPARKNS 1071
>sp|Q8IPW2|NCK_DROME SH2/SH3 adapter protein dreadlocks OS=Drosophila
melanogaster OX=7227 GN=dock PE=1 SV=2
Length=548
Score = 43.9 bits (102), Expect = 0.005, Method: Composition-based stats.
Identities = 18/49 (37%), Positives = 27/49 (55%), Gaps = 7/49 (14%)
Query 368 ELGLSFQKGDILHVIS--QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ 414
+ LSF+KGD L ++ DP+W++A +NQ GLVP Q+
Sbjct 340 DQELSFEKGDRLEIVDRPASDPDWYKAR-----NNQGQVGLVPRNYLQE 383
>sp|Q63356|MYO1E_RAT Unconventional myosin-Ie OS=Rattus norvegicus
OX=10116 GN=Myo1e PE=1 SV=1
Length=1107
Score = 43.9 bits (102), Expect = 0.005, Method: Composition-based stats.
Identities = 20/117 (17%), Positives = 33/117 (28%), Gaps = 21/117 (18%)
Query 306 GIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHV--------KAHFDYD 357
G + + + L G + + P + KA + YD
Sbjct 1003 GSDRLSQTPESLDFLKVPDQGAAGVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYD 1062
Query 358 PSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ 414
D LSF D++ +I ++ WW G GL P +
Sbjct 1063 AQDTDE-------LSFNANDVIDIIKEDPSGWWTGRLRGK------QGLFPNNYVTK 1106
>sp|C5MB30|SHO1_CANTT High osmolarity signaling protein SHO1 OS=Candida
tropicalis (strain ATCC MYA-3404 / T1) OX=294747 GN=SHO1
PE=3 SV=1
Length=340
Score = 43.5 bits (101), Expect = 0.005, Method: Composition-based stats.
Identities = 19/62 (31%), Positives = 24/62 (39%), Gaps = 11/62 (18%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
KA + YD + D +SF K +IL V D WWQA R G+ P
Sbjct 285 KALYSYDANPDDI-----NEISFVKDEILEV-DDIDGKWWQARR-----ANGQVGICPSN 333
Query 411 SF 412
Sbjct 334 YV 335
>sp|Q8QFX1|RIMB2_CHICK RIMS-binding protein 2 OS=Gallus gallus
OX=9031 GN=RIMBP2 PE=1 SV=1
Length=1325
Score = 43.9 bits (102), Expect = 0.005, Method: Composition-based stats.
Identities = 24/117 (21%), Positives = 45/117 (38%), Gaps = 8/117 (7%)
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVK---AHFDYD 357
++ N + D E+ D L + + ++ + + A +DYD
Sbjct 1178 LIPCNMVSEIQADDEEMMDQLLKQGFLPLNTPVEKIERNRRSGRQHSVSTRRMVALYDYD 1237
Query 358 PSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ 414
P + E L+F GDI+ V + D + + G+ + Q GLVP ++
Sbjct 1238 PRESSPNVDVEAELTFCTGDIITVFGEIDED---GFYYGELNGQK--GLVPSNFLEE 1289
Score = 35.4 bits (80), Expect = 2.1, Method: Composition-based stats.
Identities = 20/86 (23%), Positives = 34/86 (40%), Gaps = 10/86 (12%)
Query 332 LIPSQQIKPPPAK-ETVIHVKAHFDYDP-SDDPYVPCRELGLSFQKGDILHVI-SQEDPN 388
+ + P T I V A FDYDP + P E L F++G I+ V ++
Sbjct 1108 IYEESETDPGTEDISTRIFV-ALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADG 1166
Query 389 WWQAYREGDEDNQPLAGLVPGKSFQQ 414
+++ + GL+P +
Sbjct 1167 FYRG------ETCTRIGLIPCNMVSE 1186
>sp|Q64434|PTK6_MOUSE Protein-tyrosine kinase 6 OS=Mus musculus
OX=10090 GN=Ptk6 PE=1 SV=1
Length=451
Score = 43.5 bits (101), Expect = 0.005, Method: Composition-based stats.
Identities = 17/49 (35%), Positives = 23/49 (47%), Gaps = 1/49 (2%)
Query 368 ELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQR 416
+ LSFQ GD+LHV +E+ WW A E G VP ++
Sbjct 24 DEELSFQAGDLLHVTKKEEL-WWWATLLDAEGKALAEGYVPHNYLAEKE 71
>sp|Q8AXQ3|SH3B4_SERQU SH3 domain-binding protein 4 OS=Seriola
quinqueradiata OX=8161 GN=sh3bp4 PE=2 SV=1
Length=966
Score = 43.9 bits (102), Expect = 0.005, Method: Composition-based stats.
Identities = 14/51 (27%), Positives = 19/51 (37%), Gaps = 0/51 (0%)
Query 362 PYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSF 412
P L F KGD L+V+ WW A+ + P A + P
Sbjct 67 DCCPSSFTTLKFSKGDRLYVLDSSGAEWWYAHNNTEMGYIPAAYVEPINYR 117
>sp|Q6AYD6|PDLI2_RAT PDZ and LIM domain protein 2 OS=Rattus norvegicus
OX=10116 GN=Pdlim2 PE=1 SV=1
Length=349
Score = 43.1 bits (100), Expect = 0.005, Method: Composition-based stats.
Identities = 17/85 (20%), Positives = 30/85 (35%), Gaps = 2/85 (2%)
Query 257 VRIEKARDIPLGATVRNEMD-SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVN 315
V + + + +I++++ + G AE + L GD ++ ING
Sbjct 5 VNVVGPAPWGFRISGGRDFHTPIIVTKVTERGKAEAAD-LRPGDIIVAINGESAESMLHA 63
Query 316 EVFDLLSDMHGTLTFVLIPSQQIKP 340
E + L L SQ P
Sbjct 64 EAQSKIRQSASPLRLQLDRSQTASP 88
>sp|Q6BNP6|HSE1_DEBHA Class E vacuolar protein-sorting machinery
protein HSE1 OS=Debaryomyces hansenii (strain ATCC 36239
/ CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) OX=284592
GN=HSE1 PE=3 SV=2
Length=512
Score = 43.5 bits (101), Expect = 0.006, Method: Composition-based stats.
Identities = 25/82 (30%), Positives = 35/82 (43%), Gaps = 18/82 (22%)
Query 335 SQQIKPPPAKETVIH----VKAHFD---YDPSDDPYVPCRELGLSFQKGDILHVISQEDP 387
QQ PA+ I V+A +D Y+P + LSF+KGDI+ VI
Sbjct 241 GQQSTQSPAESQTIATVSKVRALYDLISYEPDE----------LSFRKGDIITVIESVYR 290
Query 388 NWWQAYRE-GDEDNQPLAGLVP 408
+WW+ G PL + P
Sbjct 291 DWWRGSLVNGKTGIFPLNYVTP 312
>sp|Q8IVF5|TIAM2_HUMAN Rho guanine nucleotide exchange factor
TIAM2 OS=Homo sapiens OX=9606 GN=TIAM2 PE=2 SV=4
Length=1701
Score = 43.9 bits (102), Expect = 0.006, Method: Composition-based stats.
Identities = 21/106 (20%), Positives = 42/106 (40%), Gaps = 3/106 (3%)
Query 272 RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV 331
R + + IS ++ G A G L +G+E++ +NG + D+ ++ L S+ LT +
Sbjct 913 RQHLSRIFISDVLPDGLAYGEG-LRKGNEIMTLNGEAVSDLDLKQMEALFSEKSVGLTLI 971
Query 332 LIPSQQIKPPPAKE--TVIHVKAHFDYDPSDDPYVPCRELGLSFQK 375
P + + + P + E +F+K
Sbjct 972 ARPPDTKATLCTSWSDSDLFSRDQKSLLPPPNQSQLLEEFLDNFKK 1017
>sp|Q6NU51|SH34B_XENLA SH3 domain-binding protein 4-B OS=Xenopus
laevis OX=8355 GN=sh3bp4-b PE=2 SV=1
Length=957
Score = 43.9 bits (102), Expect = 0.006, Method: Composition-based stats.
Identities = 30/112 (27%), Positives = 45/112 (40%), Gaps = 17/112 (15%)
Query 305 NGIEIRGKDVNEVFDLLSDMHGTLT-FVLI-PSQ-QIKPPPAKETVIHVKAHFDYDPSDD 361
NG+ R K + D +L+ ++ PS +I P + E V V A DY P++
Sbjct 12 NGLP-RCKSEGALIDFSGVPDPSLSEVKVLSPSSLRIDNPASLENVKEVVAIKDYCPNN- 69
Query 362 PYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
L F KG+ L+V+ +WW A N G +P Q
Sbjct 70 ------FTTLKFSKGEHLYVLDASGGDWWYA------HNTTEMGYIPSSYVQ 109
>sp|C4YDC4|SHO1_CANAW High osmolarity signaling protein SHO1 OS=Candida
albicans (strain WO-1) OX=294748 GN=SHO1 PE=3 SV=1
Length=385
Score = 43.5 bits (101), Expect = 0.006, Method: Composition-based stats.
Identities = 19/62 (31%), Positives = 24/62 (39%), Gaps = 11/62 (18%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
KA + YD + D +SF K +IL V D WWQA R G+ P
Sbjct 330 KALYSYDANPDDI-----NEISFVKDEILEV-DDIDGKWWQARR-----ANGQVGICPSN 378
Query 411 SF 412
Sbjct 379 YV 380
>sp|Q5AQ36|SHO1_CANAL High osmolarity signaling protein SHO1 OS=Candida
albicans (strain SC5314 / ATCC MYA-2876) OX=237561
GN=SHO1 PE=2 SV=2
Length=388
Score = 43.5 bits (101), Expect = 0.006, Method: Composition-based stats.
Identities = 19/62 (31%), Positives = 24/62 (39%), Gaps = 11/62 (18%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
KA + YD + D +SF K +IL V D WWQA R G+ P
Sbjct 333 KALYSYDANPDDI-----NEISFVKDEILEV-DDIDGKWWQARR-----ANGQVGICPSN 381
Query 411 SF 412
Sbjct 382 YV 383
>sp|Q9NHC3|CED2_CAEEL Cell death abnormality protein 2 OS=Caenorhabditis
elegans OX=6239 GN=ced-2 PE=1 SV=1
Length=279
Score = 42.7 bits (99), Expect = 0.006, Method: Composition-based stats.
Identities = 21/123 (17%), Positives = 44/123 (36%), Gaps = 9/123 (7%)
Query 367 RELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEED 426
RE L F++G+ L ++S+ + +WW+A + GLVP Q Q E +
Sbjct 131 RETDLPFEQGERLEILSKTNQDWWEAR-----NALGTTGLVPANYVQIQMEFHNDRTSKG 185
Query 427 KEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPAN----RKRPI 482
G + N + +T++ + + P + + +
Sbjct 186 ASQSSIGSSGGGAERFSSASTSSDNIELQPRLPAKAKVTFDRVPNAYDPTQLRVKKGQTV 245
Query 483 ILI 485
++
Sbjct 246 LVT 248
>sp|C7Z504|SHO1_FUSV7 High osmolarity signaling protein SHO1 OS=Fusarium
vanettenii (strain ATCC MYA-4622 / CBS 123669 / FGSC
9596 / NRRL 45880 / 77-13-4) OX=660122 GN=SHO1 PE=3 SV=1
Length=295
Score = 43.1 bits (100), Expect = 0.006, Method: Composition-based stats.
Identities = 24/109 (22%), Positives = 37/109 (34%), Gaps = 11/109 (10%)
Query 304 INGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPY 363
+ G+ G + V ++ P + P E KA + Y+ + D
Sbjct 195 VGGVSQVGGRGSAVPQSFTNSVMQPKATNSPGADAEVVPPTEYPYRAKAIYSYEANPDDA 254
Query 364 VPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSF 412
+SF K +IL V WWQA +E E G+ P
Sbjct 255 -----NEISFSKHEILEVSDVS-GRWWQARKENGE-----TGIAPSNYL 292
>sp|B9W8T5|SHO1_CANDC High osmolarity signaling protein SHO1 OS=Candida
dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987
/ NCPF 3949 / NRRL Y-17841) OX=573826 GN=SHO1 PE=3 SV=1
Length=398
Score = 43.5 bits (101), Expect = 0.006, Method: Composition-based stats.
Identities = 19/62 (31%), Positives = 24/62 (39%), Gaps = 11/62 (18%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
KA + YD + D +SF K +IL V D WWQA R G+ P
Sbjct 343 KALYSYDANPDDI-----NEISFVKDEILEV-DDIDGKWWQARR-----ANGQVGICPSN 391
Query 411 SF 412
Sbjct 392 YV 393
>sp|A9A0U3|MIAA_DESOH tRNA dimethylallyltransferase OS=Desulfosudis
oleivorans (strain DSM 6200 / JCM 39069 / Hxd3) OX=96561
GN=miaA PE=3 SV=1
Length=314
Score = 43.1 bits (100), Expect = 0.006, Method: Composition-based stats.
Identities = 16/78 (21%), Positives = 26/78 (33%), Gaps = 8/78 (10%)
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHT--------TRSRRDQEVAGRD 527
R R I+L GP G+ L L + + A T E A
Sbjct 6 PTRPRVIVLCGPTGVGKTRLAIALAEEFGGQIVGADSMQVYRYMDIGTAKPTPAEQARVP 65
Query 528 YHFVSRQAFEADIAAGKF 545
+H + + +AG++
Sbjct 66 HHMIDVADPDESFSAGRY 83
>sp|Q7RX59|ATM1_NEUCR Iron-sulfur clusters transporter atm1, mitochondrial
OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A
/ CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=fes-4
PE=3 SV=1
Length=716
Score = 43.5 bits (101), Expect = 0.006, Method: Composition-based stats.
Identities = 21/119 (18%), Positives = 40/119 (34%), Gaps = 22/119 (18%)
Query 462 EILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQ 521
E ++SL PA +K + ++GP CG++ L + L + +
Sbjct 461 ESPILRDLSLT-IPAGKK--VAIVGPSGCGKSTLLRLLFRFYDPQ-----------KGAI 506
Query 522 EVAGRDYHFVSRQAFEADIAA--------GKFIEHGEFEKNLYGTSIDSVRQVINSGKI 572
+ G+D V+ ++ I +EH NL T + +
Sbjct 507 YIDGQDIRSVTLESLRRAIGVVPQDTPLFNDTVEHNIRYGNLSATPEQVIEAAKAAHIH 565
>sp|Q059U7|INTU_MOUSE Protein inturned OS=Mus musculus OX=10090
GN=Intu PE=1 SV=1
Length=942
Score = 43.5 bits (101), Expect = 0.007, Method: Composition-based stats.
Identities = 12/74 (16%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query 274 EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
+ + +++ ++ GG+A KSG + GD ++ +N +++ +++ V + +
Sbjct 208 DGERLVVHGLLPGGSAMKSGQVLVGDVLVAVNDVDVTSENIERVLSCIPGPMQ-VKLTFE 266
Query 334 PSQQIKPPPAKETV 347
+ +K A+
Sbjct 267 NAYAVKRETAQPQK 280
>sp|Q8X6U5|UGPC_ECO57 sn-glycerol-3-phosphate import ATP-binding
protein UgpC OS=Escherichia coli O157:H7 OX=83334 GN=ugpC
PE=3 SV=2
Length=356
Score = 43.1 bits (100), Expect = 0.007, Method: Composition-based stats.
Identities = 28/192 (15%), Positives = 57/192 (30%), Gaps = 37/192 (19%)
Query 482 IILIGPQNCGQNELRQRLMN-KEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADI 540
I+++GP CG++ L + + + + + + + G
Sbjct 33 IVMVGPSGCGKSTLLRMVAGLERVTEGDICINDQRVTEMEPKDRGI-------------- 78
Query 541 AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPP 600
+N SV + + G L +R + + + I
Sbjct 79 --------AMVFQNYALYPHMSVEENMAWG----LKIRGMGKQQIAERVKEAARIL---- 122
Query 601 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ---ELLR 657
L LL + + + + + + FD + N D Q EL +
Sbjct 123 ---ELDGLLKRRPRELSGGQRQRVAMGRAIVRDPAVFLFDEPLSNLDAKLRVQMRLELQQ 179
Query 658 LINKLDTEPQWV 669
L +L T +V
Sbjct 180 LHRRLKTTSLYV 191
>sp|Q8AXV1|SH3G2_CHICK Endophilin-A1 OS=Gallus gallus OX=9031
GN=SH3GL2 PE=1 SV=1
Length=353
Score = 43.1 bits (100), Expect = 0.007, Method: Composition-based stats.
Identities = 24/111 (22%), Positives = 42/111 (38%), Gaps = 10/111 (9%)
Query 299 DEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV---LIPSQQIKPPPAKETVIHVKAHFD 355
D + E + R L G T + + KP A +A +D
Sbjct 242 DRIKEASSQPKREYQPKPRMSLDFTSGGDNTQHNGGISHATTPKPAGAHMDQPCCRALYD 301
Query 356 YDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGL 406
++P + E L F++GDI+ + +Q D NW++ G P+ +
Sbjct 302 FEPEN-------EGELGFKEGDIITLTNQIDENWYEGMLHGQSGFFPINYV 345
>sp|B3EQM3|MIAA_CHLPB tRNA dimethylallyltransferase OS=Chlorobium
phaeobacteroides (strain BS1) OX=331678 GN=miaA PE=3 SV=1
Length=322
Score = 42.7 bits (99), Expect = 0.007, Method: Composition-based stats.
Identities = 23/106 (22%), Positives = 37/106 (35%), Gaps = 23/106 (22%)
Query 480 RPIILI-GPQNCGQNELRQRLMNKEKDRFASAVPHT--------TRSRRDQEVAGRDYHF 530
RP++LI GP G++ L L SA T + +A YHF
Sbjct 11 RPVVLITGPTASGKSALAHALAKAINAEIVSADSRQIYRGMDIGTAKPSMEMLAEVPYHF 70
Query 531 VSRQAFEADIAAGKFIEHGEFEKNLYGTS--IDSVRQVINSGKICL 574
++ + + AG F TS + +R + G +
Sbjct 71 INEKEIAEEYNAGDF------------TSDAMARIRSIHEKGHDAI 104
>sp|Q2W8Q8|MAME_MAGSA Magnetosome formation protease MamE OS=Magnetospirillum
magneticum (strain AMB-1 / ATCC 700264) OX=342108
GN=mamE PE=1 SV=1
Length=728
Score = 43.5 bits (101), Expect = 0.007, Method: Composition-based stats.
Identities = 22/120 (18%), Positives = 43/120 (36%), Gaps = 14/120 (12%)
Query 231 EMQLEPITDERVYESIGQYGGETVK----IVRIEKARDIP----LGATVRNEMD-SVIIS 281
+ G GG++ V + A P LGA + V IS
Sbjct 460 AYRFAQPPGSLAINIQGPRGGQSTAAGTGRVTLLGAALTPMSQRLGAQTGVPVGRGVFIS 519
Query 282 RIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD--MHGTLTFVLIPSQQIK 339
+ A +G L GD +L+++G +R EV ++ + ++ ++ ++
Sbjct 520 GVTPNTPAATAG-LRPGDVLLKVDGRPVR--LPEEVSAIMVEMHAGRSVRLGVLRDGDVR 576
Score = 38.9 bits (89), Expect = 0.18, Method: Composition-based stats.
Identities = 13/79 (16%), Positives = 29/79 (37%), Gaps = 3/79 (4%)
Query 263 RDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG-KDVNEVFDLL 321
+P GA ++ ++ G A +G L D +LE+N + G ++
Sbjct 649 TGVP-GAVPVPGAKGAQVAEVLVGSRAAVAG-LQANDLILEVNNRPVAGPARLDAAIKGA 706
Query 322 SDMHGTLTFVLIPSQQIKP 340
++ + + + Q
Sbjct 707 TNAGQQILLKVNRNGQEFW 725
>sp|Q9Y2H9|MAST1_HUMAN Microtubule-associated serine/threonine-protein
kinase 1 OS=Homo sapiens OX=9606 GN=MAST1 PE=1 SV=2
Length=1570
Score = 43.5 bits (101), Expect = 0.007, Method: Composition-based stats.
Identities = 24/100 (24%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
Query 279 IISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP--SQ 336
I+ + +GG A+++G L GD + +NG + G EV +L+ + P +
Sbjct 999 IVWHVEEGGPAQEAG-LCAGDLITHVNGEPVHGMVHPEVVELILKSGNKVAVTTTPFENT 1057
Query 337 QIKPPPAKETVIHVK-AHFDYDPSDDPYVPCRELGLSFQK 375
I+ PA+ + K A + PS ++ F+K
Sbjct 1058 SIRIGPARRSSYKAKMARRNKRPSAKEGQESKKRSSLFRK 1097
>sp|Q9PL97|DEGPL_CHLMU Probable periplasmic serine endoprotease
DegP-like OS=Chlamydia muridarum (strain MoPn / Nigg) OX=243161
GN=htrA PE=3 SV=1
Length=497
Score = 43.1 bits (100), Expect = 0.007, Method: Composition-based stats.
Identities = 28/182 (15%), Positives = 65/182 (36%), Gaps = 16/182 (9%)
Query 161 NAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLN--TPHIQ 218
K++ A+ + K SP A ++V + L ++ P +
Sbjct 318 KLEKVYGALITDVVKGSPA----EKAGLRQEDVIVAYNGKEVESLSALRNAISLMMPGTR 373
Query 219 ALLLAHDKVAEQEMQLEPITDERVYESIGQYGGET--VKIVRIEKARDIPLGATVRNEMD 276
+L V E + P+T ++ G + V++ + LG ++
Sbjct 374 VVLKV---VREGKFIEIPVTVTQIPAEDGVSALQKMGVRVQNLTPEICKKLGLA--SDTR 428
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQ 336
+ + + G A +G + G +L +N + V E+ +L + G +++
Sbjct 429 GIFVVSVEAGSPAASAG-VVPGQLILAVNRQRVS--SVEELNQVLKNAKGENVLLMVSQG 485
Query 337 QI 338
++
Sbjct 486 EV 487
Score = 41.6 bits (96), Expect = 0.026, Method: Composition-based stats.
Identities = 22/102 (22%), Positives = 41/102 (40%), Gaps = 10/102 (10%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
++ +I+ +VKG AEK+GL E D ++ NG E+ L + +
Sbjct 320 EKVYGALITDVVKGSPAEKAGLRQE-DVIVAYNGKEVESLSALRNAISLMMPGTRVVLKV 378
Query 333 IPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQ 374
+ + P T I P++D +++G+ Q
Sbjct 379 VREGKFIEIPVTVTQI---------PAEDGVSALQKMGVRVQ 411
>sp|Q5LLN2|COAE_RUEPO Dephospho-CoA kinase OS=Ruegeria pomeroyi
(strain ATCC 700808 / DSM 15171 / DSS-3) OX=246200 GN=coaE
PE=3 SV=1
Length=197
Score = 42.0 bits (97), Expect = 0.008, Method: Composition-based stats.
Identities = 12/65 (18%), Positives = 26/65 (40%), Gaps = 4/65 (6%)
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRL 658
PP E +A + G + + + ++ E+ D IV LD A ++ +
Sbjct 131 PP--EEQKARVMARGTMTEAQFEQIRAKQMPNEEKCARS--DFVIVTDTLDHARAQVQDI 186
Query 659 INKLD 663
+ ++
Sbjct 187 VRQIR 191
>sp|P31693|SRC_RSVPA Tyrosine-protein kinase transforming protein
Src OS=Rous sarcoma virus (strain PA101T) OX=31667 GN=V-SRC
PE=3 SV=3
Length=523
Score = 43.1 bits (100), Expect = 0.008, Method: Composition-based stats.
Identities = 11/46 (24%), Positives = 19/46 (41%), Gaps = 4/46 (9%)
Query 368 ELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
E LSF+K + L +++ + WW A+ G +P
Sbjct 94 ETDLSFKKRERLQIVNNTEGTWWLAH----SLTTGQTGYIPSNYVA 135
>sp|B8MD74|SHO1_TALSN High osmolarity signaling protein sho1 OS=Talaromyces
stipitatus (strain ATCC 10500 / CBS 375.48 / QM
6759 / NRRL 1006) OX=441959 GN=sho1 PE=3 SV=1
Length=281
Score = 42.4 bits (98), Expect = 0.008, Method: Composition-based stats.
Identities = 22/81 (27%), Positives = 30/81 (37%), Gaps = 13/81 (16%)
Query 332 LIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQ 391
+ PS ++ P E KA + YD + D +SF KG+ L V WWQ
Sbjct 211 VEPSNEVSQPT--EYPYKAKAIYSYDANPDDA-----NEISFTKGEELEVSDVS-GRWWQ 262
Query 392 AYREGDEDNQPLAGLVPGKSF 412
A R G+ P
Sbjct 263 ARR-----ANGETGIAPSNYL 278
>sp|Q5U228|SH3B4_XENTR SH3 domain-binding protein 4 OS=Xenopus
tropicalis OX=8364 GN=sh3bp4 PE=2 SV=1
Length=957
Score = 43.5 bits (101), Expect = 0.008, Method: Composition-based stats.
Identities = 28/112 (25%), Positives = 43/112 (38%), Gaps = 17/112 (15%)
Query 305 NGIEIRGKDVNEVFDLLSDMHGTLT-FVLI-PSQ-QIKPPPAKETVIHVKAHFDYDPSDD 361
NG+ R K + D L+ ++ PS ++ P + + V V A DY P++
Sbjct 12 NGLP-RCKSEGALIDFSGVPDPNLSDVKVLSPSSLRVDNPASLDNVKEVVAIKDYCPNN- 69
Query 362 PYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
L F KG+ L+V+ WW A N G +P Q
Sbjct 70 ------FTTLKFSKGEHLYVLDTSGGEWWYA------HNTTEMGYIPSSYVQ 109
>sp|A0A8J9WHR9|PHOO1_DIALO ABC-type transporter phomO OS=Diaporthe
leptostromiformis OX=291059 GN=phomO PE=3 SV=1
Length=1551
Score = 43.5 bits (101), Expect = 0.008, Method: Composition-based stats.
Identities = 18/105 (17%), Positives = 50/105 (48%), Gaps = 11/105 (10%)
Query 406 LVPGKSFQ----QQREAMKQTIEEDKEPEKSGKLWCA-KKNKKKRKKVLYNANKNDDY-- 458
++P ++ +A + E E +++ + + + +K+K+ + + N +
Sbjct 593 IIPSFGAALGSLERIDAFFEKQEFTDERDEATAVDSSCSEKGEKKKEHVSLSIHNSSFSY 652
Query 459 -DNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNK 502
D+ E ++++L NR + +++ GP CG++ L Q ++ +
Sbjct 653 TDDSEDSILKDVNLV---INRGQHVVVTGPAGCGKSLLLQAILGE 694
>sp|B1I462|DER_DESAP GTPase Der OS=Desulforudis audaxviator (strain
MP104C) OX=477974 GN=der PE=3 SV=1
Length=438
Score = 43.1 bits (100), Expect = 0.008, Method: Composition-based stats.
Identities = 22/104 (21%), Positives = 41/104 (39%), Gaps = 3/104 (3%)
Query 450 YNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFAS 509
A + D +++ + +P + I ++G N G++ L ++ +E+ S
Sbjct 146 SAAQGLNIGDLLDLVVAGMPAGADEPRSEPVRIAVVGRPNVGKSSLVNAILGEER-VIVS 204
Query 510 AVPHTTRSRRDQ--EVAGRDYHFVSRQAFEADIAAGKFIEHGEF 551
VP TTR D GR+Y F+ + IE+
Sbjct 205 DVPGTTRDAVDTLFRRDGREYVFIDTAGMRRKARIRESIEYYSV 248
>sp|A4SK24|AROK_AERS4 Shikimate kinase OS=Aeromonas salmonicida
(strain A449) OX=382245 GN=aroK PE=3 SV=1
Length=172
Score = 41.2 bits (95), Expect = 0.008, Method: Composition-based stats.
Identities = 29/174 (17%), Positives = 58/174 (33%), Gaps = 26/174 (15%)
Query 479 KRPIILIGPQNCGQNELRQRLMNK-EKDRFASAVPHTTRSRRD----QEVAGRDYHFVSR 533
KR I LIGP G++ + + L + + F S RS D +V G + +
Sbjct 4 KRNIFLIGPMGAGKSTIGRHLAEQLHMEFFDSDHEIERRSGADIGWVFDVEGEEGFRIRE 63
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ D++ + I + S ++ ++ G + L + K L +
Sbjct 64 EKVIGDLSEQQGIVLATGGGAIK--SRETRNKLSARGIVVYLETTIE--KQLARTQRD-- 117
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD 647
+ + + P E L + ++ + + D I D
Sbjct 118 ------------KRRPLLQTEEPPREVLERLAQERNALYEEVA---DFVIQTDD 156
>sp|A0KN29|AROK_AERHH Shikimate kinase OS=Aeromonas hydrophila
subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018
/ CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049)
OX=380703 GN=aroK PE=3 SV=1
Length=172
Score = 41.2 bits (95), Expect = 0.008, Method: Composition-based stats.
Identities = 29/174 (17%), Positives = 58/174 (33%), Gaps = 26/174 (15%)
Query 479 KRPIILIGPQNCGQNELRQRLMNK-EKDRFASAVPHTTRSRRD----QEVAGRDYHFVSR 533
KR I LIGP G++ + + L + + F S RS D +V G + +
Sbjct 4 KRNIFLIGPMGAGKSTIGRHLAEQLHMEFFDSDHEIERRSGADIGWVFDVEGEEGFRIRE 63
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPY 593
+ D++ + I + S ++ ++ G + L + K L +
Sbjct 64 EKVIGDLSEQQGIVLATGGGAIK--SRETRNKLSARGIVVYLETTIE--KQLARTQRD-- 117
Query 594 IIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSD 647
+ + + P E L + ++ + + D I D
Sbjct 118 ------------KRRPLLQTEEPPREVLERLAQERNALYEEVA---DFVIQTDD 156
>sp|A5E1V8|SHO1_LODEL High osmolarity signaling protein SHO1 OS=Lodderomyces
elongisporus (strain ATCC 11503 / CBS 2605 /
JCM 1781 / NBRC 1676 / NRRL YB-4239) OX=379508 GN=SHO1 PE=3
SV=1
Length=324
Score = 42.7 bits (99), Expect = 0.008, Method: Composition-based stats.
Identities = 19/62 (31%), Positives = 24/62 (39%), Gaps = 11/62 (18%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
KA + YD + D +SF K +IL V D WWQA R G+ P
Sbjct 269 KALYSYDANPDDI-----NEISFIKDEILDV-DDVDGKWWQARR-----ANGQVGICPSN 317
Query 411 SF 412
Sbjct 318 YV 319
>sp|Q8QFP8|LIMK1_CHICK LIM domain kinase 1 OS=Gallus gallus OX=9031
GN=LIMK1 PE=1 SV=1
Length=662
Score = 43.1 bits (100), Expect = 0.009, Method: Composition-based stats.
Identities = 29/158 (18%), Positives = 57/158 (36%), Gaps = 22/158 (14%)
Query 234 LEPITDERVYESIGQYGGETVKIVRI------EKARDIPLGATVRNEMDS------VIIS 281
+ P+ ++ + +S G TV +V I ++ + + + V +
Sbjct 144 VTPVIEQILPDSPGSRIPHTVTLVSIPACSDGKRGFSVSIDPHCGAQGCGAEHSRTVRVR 203
Query 282 RIVKGGAA-EKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKP 340
+ + + +H GD +LEING I ++E+ L+ + L + +P
Sbjct 204 EVDPDCISPDVKNSIHVGDRILEINGTPIGHVPLDEIDLLIQETSRLLQLTIE-HDPHEP 262
Query 341 PPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDI 378
P P DP+ P R + GD+
Sbjct 263 LPRDLA-------LPCSPLPDPHSPLRSP-VPAPHGDL 292
>sp|Q95M30|HCK_MACFA Tyrosine-protein kinase HCK OS=Macaca fascicularis
OX=9541 GN=HCK PE=2 SV=3
Length=504
Score = 43.1 bits (100), Expect = 0.009, Method: Composition-based stats.
Identities = 22/93 (24%), Positives = 31/93 (33%), Gaps = 15/93 (16%)
Query 324 MHGTLTFVLIPSQQIKPPPA---KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILH 380
T T P+ + P I V A +DY+ LSFQKGD +
Sbjct 32 PDPTSTIKPGPNSNNRNTPGIGEGSEDIIVVALYDYEAIHHED-------LSFQKGDQMV 84
Query 381 VISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
V+ + WW+A G +P
Sbjct 85 VLEES-GEWWKAR----SLATRKEGYIPSNYVA 112
>sp|Q4R729|SH321_MACFA SH3 domain-containing protein 21 OS=Macaca
fascicularis OX=9541 GN=SH3D21 PE=2 SV=1
Length=692
Score = 43.1 bits (100), Expect = 0.009, Method: Composition-based stats.
Identities = 23/117 (20%), Positives = 43/117 (37%), Gaps = 11/117 (9%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ--EDPNWWQAYREGDEDNQPLAGLVP 408
+ FDY P L+ ++GD++ V+S+ ED WW+ +G P ++P
Sbjct 71 RVLFDYQPEAPDE-------LTLRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFVLP 123
Query 409 GKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILT 465
++ ++ + P K K K + KK+ A +
Sbjct 124 PPPI--KKLVPRKVVSRQSAPIKEPKKLMPKTSLPTVKKLATAATGPSKAKTSRTPS 178
>sp|P32577|CSK_RAT Tyrosine-protein kinase CSK OS=Rattus norvegicus
OX=10116 GN=Csk PE=1 SV=1
Length=450
Score = 42.7 bits (99), Expect = 0.009, Method: Composition-based stats.
Identities = 15/50 (30%), Positives = 27/50 (54%), Gaps = 6/50 (12%)
Query 368 ELGLSFQKGDILHVIS-QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQR 416
E L F KGD+L +++ +DPNW++A + G++P Q++
Sbjct 25 EQDLPFCKGDVLTIVAVTKDPNWYKAK-----NKVGREGIIPANYVQKRE 69
>sp|P41241|CSK_MOUSE Tyrosine-protein kinase CSK OS=Mus musculus
OX=10090 GN=Csk PE=1 SV=2
Length=450
Score = 42.7 bits (99), Expect = 0.009, Method: Composition-based stats.
Identities = 15/50 (30%), Positives = 27/50 (54%), Gaps = 6/50 (12%)
Query 368 ELGLSFQKGDILHVIS-QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQR 416
E L F KGD+L +++ +DPNW++A + G++P Q++
Sbjct 25 EQDLPFCKGDVLTIVAVTKDPNWYKAK-----NKVGREGIIPANYVQKRE 69
>sp|P41240|CSK_HUMAN Tyrosine-protein kinase CSK OS=Homo sapiens
OX=9606 GN=CSK PE=1 SV=1
Length=450
Score = 42.7 bits (99), Expect = 0.009, Method: Composition-based stats.
Identities = 15/50 (30%), Positives = 27/50 (54%), Gaps = 6/50 (12%)
Query 368 ELGLSFQKGDILHVIS-QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQR 416
E L F KGD+L +++ +DPNW++A + G++P Q++
Sbjct 25 EQDLPFCKGDVLTIVAVTKDPNWYKAK-----NKVGREGIIPANYVQKRE 69
>sp|Q0VBZ0|CSK_BOVIN Tyrosine-protein kinase CSK OS=Bos taurus
OX=9913 GN=CSK PE=2 SV=1
Length=450
Score = 42.7 bits (99), Expect = 0.009, Method: Composition-based stats.
Identities = 15/50 (30%), Positives = 27/50 (54%), Gaps = 6/50 (12%)
Query 368 ELGLSFQKGDILHVIS-QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQR 416
E L F KGD+L +++ +DPNW++A + G++P Q++
Sbjct 25 EQDLPFCKGDVLTIVAVTKDPNWYKAK-----NKVGREGIIPANYVQKRE 69
>sp|Q9H987|SYP2L_HUMAN Synaptopodin 2-like protein OS=Homo sapiens
OX=9606 GN=SYNPO2L PE=1 SV=3
Length=977
Score = 43.1 bits (100), Expect = 0.010, Method: Composition-based stats.
Identities = 18/98 (18%), Positives = 32/98 (33%), Gaps = 2/98 (2%)
Query 249 YGGETVKIVRIEKARDIPLGATVRNEM-DSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
G E +V + E + +S+I + A ++G L E D++L ING+
Sbjct 1 MGAEEEVLVTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAG-LRERDQLLAINGV 59
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKE 345
L+ L + P +
Sbjct 60 SCTNLSHASAMSLIDASGNQLVLTVQRLADEGPVQSPS 97
>sp|Q2QV81|AB49G_ORYSJ ABC transporter G family member 49 OS=Oryza
sativa subsp. japonica OX=39947 GN=ABCG49 PE=2 SV=3
Length=1480
Score = 43.1 bits (100), Expect = 0.010, Method: Composition-based stats.
Identities = 19/101 (19%), Positives = 37/101 (37%), Gaps = 7/101 (7%)
Query 402 PLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNE 461
G+ P + R+ + + + LW A + L A +
Sbjct 168 ERVGVRPATVEVRWRDVCVEAECQVVSGKPLPTLWNAAL----SRFSLLAAKLGFSHHQS 223
Query 462 EILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNK 502
++ E +S +P+ R +L+GP CG+ L + L +
Sbjct 224 KVQILENVSGIIKPS---RITLLLGPPGCGKTTLLKALAGR 261
>sp|Q9VU84|DBNL_DROME Drebrin-like protein OS=Drosophila melanogaster
OX=7227 GN=Abp1 PE=1 SV=1
Length=531
Score = 42.7 bits (99), Expect = 0.010, Method: Composition-based stats.
Identities = 18/63 (29%), Positives = 27/63 (43%), Gaps = 12/63 (19%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
+A +DY +D E ++F GD++ I Q D WWQ G + GL P
Sbjct 478 RALYDYQAAD-------ETEITFDPGDVITHIDQIDEGWWQG--LGPDGTY---GLFPAN 525
Query 411 SFQ 413
+
Sbjct 526 YVE 528
>sp|B2V5W6|DER_SULSY GTPase Der OS=Sulfurihydrogenibium sp. (strain
YO3AOP1) OX=436114 GN=der PE=3 SV=1
Length=445
Score = 42.7 bits (99), Expect = 0.010, Method: Composition-based stats.
Identities = 21/104 (20%), Positives = 42/104 (40%), Gaps = 13/104 (13%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRD--QEVAGRDYHFVSRQAFEAD 539
+ ++G N G++ L L+N+E+ S +P TTR D E G+ + F+
Sbjct 184 VAIVGKPNAGKSSLINALLNEER-VLVSEIPGTTRDTVDILYEKDGQKFLFLDTAGMRKK 242
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRT-QSL 582
+E G +I+++ + + +L + Q
Sbjct 243 SKVDFGLEFFSV-----GRTIEAIEKA----DVVVLVIDANQGA 277
>sp|F4JT78|RPP2A_ARATH Disease resistance protein RPP2A OS=Arabidopsis
thaliana OX=3702 GN=RPP2A PE=2 SV=1
Length=1309
Score = 43.1 bits (100), Expect = 0.010, Method: Composition-based stats.
Identities = 8/40 (20%), Positives = 18/40 (45%), Gaps = 0/40 (0%)
Query 470 SLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFAS 509
S+ + + R + + GP G+ + + L +K +F
Sbjct 195 SILRLKSEKARMVGISGPSGIGKTTIAKALFSKLSPQFHL 234
>sp|D4ACE5|INTU_RAT Protein inturned OS=Rattus norvegicus OX=10116
GN=Intu PE=1 SV=1
Length=942
Score = 43.1 bits (100), Expect = 0.010, Method: Composition-based stats.
Identities = 13/74 (18%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query 274 EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
+ + +++ +V GG+A KSG + GD ++ +N +++ +++ V + +
Sbjct 208 DGERLVVHGLVPGGSAMKSGQVLVGDVLVAVNDVDVTSENIERVLSCIPGPMQ-VKLTFE 266
Query 334 PSQQIKPPPAKETV 347
+ +K A+
Sbjct 267 NAYAVKKETAQPKK 280
>sp|F4KHH8|RPS6C_ARATH Disease resistance protein RPS6 OS=Arabidopsis
thaliana OX=3702 GN=RPS6 PE=1 SV=1
Length=1127
Score = 43.1 bits (100), Expect = 0.010, Method: Composition-based stats.
Identities = 14/62 (23%), Positives = 29/62 (47%), Gaps = 5/62 (8%)
Query 455 NDDYDNEEILTYEE-----MSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFAS 509
+ D E+++ E+ SL H + R + + GP G+ + + L ++ +F S
Sbjct 179 SPSNDFEDLVGIEDHITKMSSLLHLESEEVRMVGIWGPSGIGKTTIARALFSRLSCQFQS 238
Query 510 AV 511
+V
Sbjct 239 SV 240
>sp|P35991|BTK_MOUSE Tyrosine-protein kinase BTK OS=Mus musculus
OX=10090 GN=Btk PE=1 SV=4
Length=659
Score = 42.7 bits (99), Expect = 0.010, Method: Composition-based stats.
Identities = 29/171 (17%), Positives = 62/171 (36%), Gaps = 15/171 (9%)
Query 291 KSGLLHEGDEVLE-INGIEIRGKDVNEVFDLLSDMHGT--LTFVLIPSQQIKPPPAKETV 347
++ G ++LE NG G + L + +P + P + +
Sbjct 157 QTAKNAMGCQILENRNGSLKPGSSHRKTKKPLPPTPEEDQILKKPLPPEPTAAPISTTEL 216
Query 348 IHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLV 407
V A +DY P + L +KG+ ++ + + WW+A D G +
Sbjct 217 KKVVALYDYMPMNAND-------LQLRKGEEYFILEESNLPWWRAR-----DKNGQEGYI 264
Query 408 PGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDY 458
P + ++++ K +S K+ K+ ++ +++K Y
Sbjct 265 PSNYITEAEDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKAGKY 315
>sp|Q9PLM3|DER_CHLMU GTPase Der OS=Chlamydia muridarum (strain
MoPn / Nigg) OX=243161 GN=der PE=3 SV=1
Length=490
Score = 42.7 bits (99), Expect = 0.011, Method: Composition-based stats.
Identities = 30/141 (21%), Positives = 52/141 (37%), Gaps = 17/141 (12%)
Query 454 KNDDYDNEEILTYEEM---SLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASA 510
+N+ EE EE+ + +NR + LIG N G++ + L+ +E+
Sbjct 198 ENESLSQEEASFLEELVAQTTTPSISNRPLKVALIGHPNVGKSSIVNALLKEER-CITDN 256
Query 511 VPHTTRSRRD--QEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVIN 568
P TTR D ++Y F+ + +E S + I+
Sbjct 257 SPGTTRDNVDVSYTYNDKEYVFIDTAGLRKAKSIKNSVEWM---------SSSRTEKAIS 307
Query 569 SGKICLLSLRTQSLKTLRNSD 589
ICLL + + + L D
Sbjct 308 RADICLLVID--ATQQLSYQD 326
>sp|A0QSH8|KAD_MYCS2 Adenylate kinase OS=Mycolicibacterium smegmatis
(strain ATCC 700084 / mc(2)155) OX=246196 GN=adk PE=1
SV=1
Length=181
Score = 41.2 bits (95), Expect = 0.011, Method: Composition-based stats.
Identities = 34/197 (17%), Positives = 63/197 (32%), Gaps = 35/197 (18%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++L+GP G+ ++L ++ T R G + +
Sbjct 3 VVLLGPPGAGKGTQAEKL----SEKLGIPQISTGDLFRKNIGDGTPLGL----EAKRYLD 54
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKIC---LLS-----LRTQSLKT----LRNSD 589
AG + E L V I+ +L + RN+
Sbjct 55 AGDLVP-AELTNRL-------VEDRIDQPDAAEGFILDGYPRSVEQAGALKDMLAARNTK 106
Query 590 LKPYIIFIAPPSQERLRALLAKEGK-NPKPEELREIIEKTREMEQNNGHYF--DTAIVN- 645
L + F S++ L L G+ + E +R ++ RE + Y+ D VN
Sbjct 107 LDAVLEFQV--SEDELLTRLKGRGRADDTDEVIRNRMKVYREETEPLLEYYRDDLKTVNA 164
Query 646 -SDLDKAYQELLRLINK 661
LD+ + L + +
Sbjct 165 VGALDEVFARALSALGQ 181
>sp|Q9NYB9|ABI2_HUMAN Abl interactor 2 OS=Homo sapiens OX=9606
GN=ABI2 PE=1 SV=1
Length=513
Score = 42.7 bits (99), Expect = 0.011, Method: Composition-based stats.
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 11/75 (15%)
Query 339 KPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDE 398
+ PP K YD + D +E LSFQ+G I++VI + D W++ G
Sbjct 443 EDPPWAPRSYLEKVVAIYDYTKD-----KEDELSFQEGAIIYVIKKNDDGWYEGVMNG-- 495
Query 399 DNQPLAGLVPGKSFQ 413
+ GL PG +
Sbjct 496 ----VTGLFPGNYVE 506
>sp|Q9JIR1|RIMB2_RAT RIMS-binding protein 2 OS=Rattus norvegicus
OX=10116 GN=Rimbp2 PE=1 SV=2
Length=1049
Score = 42.7 bits (99), Expect = 0.012, Method: Composition-based stats.
Identities = 24/117 (21%), Positives = 43/117 (37%), Gaps = 8/117 (7%)
Query 301 VLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVK---AHFDYD 357
++ N + D E+ D L + + + + + A +DYD
Sbjct 905 LIPCNMVSEIHADDEEMMDQLLRQGFLPLNTPVEKIERSRRSGRGHSVPTRRMVALYDYD 964
Query 358 PSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ 414
P + E L F GDI+ V + D + + G+ + Q GLVP ++
Sbjct 965 PRESSPNVDVEAELLFCTGDIITVFGEIDED---GFYYGELNGQK--GLVPSNFLEE 1016
>sp|Q64XX2|MIAA1_BACFR tRNA dimethylallyltransferase 1 OS=Bacteroides
fragilis (strain YCH46) OX=295405 GN=miaA1 PE=3 SV=1
Length=301
Score = 42.0 bits (97), Expect = 0.012, Method: Composition-based stats.
Identities = 21/105 (20%), Positives = 36/105 (34%), Gaps = 19/105 (18%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHT--------TRSRRDQEVAGRDYHF 530
K I+LIGP G+ EL R+ K S+ T + +++ ++F
Sbjct 4 KTLIVLIGPTGVGKTELSLRIAEYFKTSIISSDSRQLYAELKIGTAAPTPEQLKRVPHYF 63
Query 531 VSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLL 575
V G + Y T + SV + + +L
Sbjct 64 V-----------GTLQLTDYYSAAQYETEVMSVLEQLFQQHHVVL 97
>sp|D8PSG0|SHO1_SCHCM High osmolarity signaling protein SHO1 OS=Schizophyllum
commune (strain H4-8 / FGSC 9210) OX=578458
GN=SHO1 PE=3 SV=1
Length=331
Score = 42.0 bits (97), Expect = 0.012, Method: Composition-based stats.
Identities = 35/192 (18%), Positives = 57/192 (30%), Gaps = 48/192 (25%)
Query 224 HDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRI 283
HD VA +P++ S G + GA + + +R
Sbjct 184 HD-VATGAYDAKPVSGAFDARSGTASGAFD--------NKSAGAGAGLNSPGGG---ARS 231
Query 284 VK--GGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
GG +G +H G + G + G ++ + +
Sbjct 232 QHSLGGPTTATGSVH------SPRGEDGTGSPL--------MAQGDMSGAGTSGEFLPKA 277
Query 342 PAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQ 401
KA + Y S D +SF KG+IL V + WW A + +
Sbjct 278 ---------KALYAYTASPDD-----PNEISFAKGEILEVTDKSGK-WWSARKADGTN-- 320
Query 402 PLAGLVPGKSFQ 413
G+ P Q
Sbjct 321 ---GIAPSNYLQ 329
>sp|Q2KEW0|SHO1_PYRO7 Cell surface sensor SHO1 OS=Pyricularia
oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) OX=242507
GN=SHO1 PE=2 SV=2
Length=318
Score = 42.0 bits (97), Expect = 0.012, Method: Composition-based stats.
Identities = 25/112 (22%), Positives = 37/112 (33%), Gaps = 14/112 (13%)
Query 304 INGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQ---QIKPPPAKETVIHVKAHFDYDPSD 360
+NG+ G + G P+ + P E KA + Y+ +
Sbjct 215 VNGMRNSGAPPSGFPTTPGPASGLPKTTTPPAGGAADAEIVPPTEYPYRAKAIYTYEANP 274
Query 361 DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSF 412
D +SF K +IL V WWQA +E E G+ P
Sbjct 275 DDA-----NEISFSKHEILEVSDVS-GRWWQARKETGE-----TGIAPSNYL 315
>sp|O35179|SH3G2_RAT Endophilin-A1 OS=Rattus norvegicus OX=10116
GN=Sh3gl2 PE=1 SV=2
Length=352
Score = 42.0 bits (97), Expect = 0.013, Method: Composition-based stats.
Identities = 15/56 (27%), Positives = 29/56 (52%), Gaps = 7/56 (13%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGL 406
+A +D++P + E L F++GDI+ + +Q D NW++ G P+ +
Sbjct 296 RALYDFEPEN-------EGELGFKEGDIITLTNQIDENWYEGMLHGQSGFFPINYV 344
>sp|Q5LH18|MIAA1_BACFN tRNA dimethylallyltransferase 1 OS=Bacteroides
fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 /
JCM 11019 / NCTC 9343 / Onslow) OX=272559 GN=miaA1 PE=3 SV=1
Length=301
Score = 42.0 bits (97), Expect = 0.013, Method: Composition-based stats.
Identities = 21/105 (20%), Positives = 36/105 (34%), Gaps = 19/105 (18%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHT--------TRSRRDQEVAGRDYHF 530
K I+LIGP G+ EL R+ K S+ T + +++ ++F
Sbjct 4 KTLIVLIGPTGVGKTELSLRIAEYFKTSIISSDSRQLYAELKIGTAAPTPEQLKRVPHYF 63
Query 531 VSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLL 575
V G + Y T + SV + + +L
Sbjct 64 V-----------GTLQLTDYYSAAQYETEVMSVLEQLFQQHHVVL 97
>sp|Q99963|SH3G3_HUMAN Endophilin-A3 OS=Homo sapiens OX=9606 GN=SH3GL3
PE=1 SV=1
Length=347
Score = 42.0 bits (97), Expect = 0.013, Method: Composition-based stats.
Identities = 20/121 (17%), Positives = 47/121 (39%), Gaps = 35/121 (29%)
Query 314 VNEVFDLLSDMHGTLTFVL-----IPSQQIKPPPAKETVIHV------------------ 350
+ ++L ++ L + +P ++ KP P K + +
Sbjct 226 HRQSTEILQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPM 285
Query 351 -----KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAG 405
+ +D++P + + L F++GDI+ + +Q D NW++ G+ P+
Sbjct 286 DQPCCRGLYDFEPEN-------QGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINY 338
Query 406 L 406
+
Sbjct 339 V 339
>sp|B4HEM8|HTRA2_DROSE Serine protease HTRA2, mitochondrial OS=Drosophila
sechellia OX=7238 GN=HtrA2 PE=3 SV=1
Length=422
Score = 42.4 bits (98), Expect = 0.013, Method: Composition-based stats.
Identities = 21/64 (33%), Positives = 32/64 (50%), Gaps = 3/64 (5%)
Query 272 RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV 331
N V++ +++ G A SG L GD V IN EI+ +V+D L+D TL V
Sbjct 349 SNLTHGVLVWKVIVGSPAH-SGGLQPGDIVTHINKKEIKNSS--DVYDALADNSKTLDIV 405
Query 332 LIPS 335
++
Sbjct 406 ILRG 409
>sp|Q9VFJ3|HTRA2_DROME Serine protease HTRA2, mitochondrial OS=Drosophila
melanogaster OX=7227 GN=HtrA2 PE=1 SV=1
Length=422
Score = 42.4 bits (98), Expect = 0.013, Method: Composition-based stats.
Identities = 21/64 (33%), Positives = 32/64 (50%), Gaps = 3/64 (5%)
Query 272 RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV 331
N V++ +++ G A SG L GD V IN EI+ +V+D L+D TL V
Sbjct 349 SNLTHGVLVWKVIVGSPAH-SGGLQPGDIVTHINKKEIKNSS--DVYDALADNSKTLDIV 405
Query 332 LIPS 335
++
Sbjct 406 ILRG 409
>sp|B2THS4|RSGA_CLOBB Small ribosomal subunit biogenesis GTPase
RsgA OS=Clostridium botulinum (strain Eklund 17B / Type B)
OX=935198 GN=rsgA PE=3 SV=1
Length=290
Score = 42.0 bits (97), Expect = 0.013, Method: Composition-based stats.
Identities = 29/116 (25%), Positives = 41/116 (35%), Gaps = 24/116 (21%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKE-------KDRFASAVPHTTRSRRDQEV-AG--RDY 528
+L GP G++ L +L NKE ++ HTTR EV G D
Sbjct 154 GNITVLCGPSGAGKSTLINKLTNKEHMLTGIVSEKIGRGK-HTTRHSELIEVSNGYIVDT 212
Query 529 HFVSRQAFEADIAAG-------KFIEHGEFEKNLYGT-----SIDSVRQVINSGKI 572
S + + +F EH E K G +V+Q + GKI
Sbjct 213 PGFSTLEIKELMNKEDLKYCFPEFEEHNESCK-YRGCLHNKEPKCTVKQAVEEGKI 267
>sp|Q3IQI3|PSTB2_NATPD Phosphate import ATP-binding protein PstB
2 OS=Natronomonas pharaonis (strain ATCC 35678 / DSM 2160
/ CIP 103997 / JCM 8858 / NBRC 14720 / NCIMB 2260 / Gabara)
OX=348780 GN=pstB2 PE=3 SV=1
Length=284
Score = 42.0 bits (97), Expect = 0.013, Method: Composition-based stats.
Identities = 15/92 (16%), Positives = 34/92 (37%), Gaps = 7/92 (8%)
Query 416 REAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQP 475
+ + I + + + ++ L A + +D +L E ++L
Sbjct 3 LLSTLRGISSPARQQPGTQSESRRGGDTLAERGLAVAGVSHGFDGTAVL--ESVTLA--- 57
Query 476 ANRKRPIILIGPQNCGQNELRQ--RLMNKEKD 505
+R + +IGP G+ L + L ++ D
Sbjct 58 VDRGETVAIIGPSGTGKTTLLRLLALFSEPDD 89
>sp|Q03E60|KTHY_PEDPA Thymidylate kinase OS=Pediococcus pentosaceus
(strain ATCC 25745 / CCUG 21536 / LMG 10740 / 183-1w)
OX=278197 GN=tmk PE=3 SV=1
Length=209
Score = 41.2 bits (95), Expect = 0.013, Method: Composition-based stats.
Identities = 22/202 (11%), Positives = 68/202 (34%), Gaps = 29/202 (14%)
Query 486 GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKF 545
GP G+ + Q ++ + R + T + + + E D
Sbjct 10 GPDGAGKTTVLQAMVEHYQQRLKDQLTVTREPGGNPISEAIRTIILDKNNTEMDERTEAL 69
Query 546 IEHGEFEKNLYGTSIDSVRQVINSGKICLLS------LRTQSL------KTLRNSDLKP- 592
+ ++L ++++ + + + Q + +L
Sbjct 70 LYAAARRQHL----VETILPALKKNHVVFCDRFVDSSIAYQGAGRKIGTDAVYQMNLFAT 125
Query 593 ------YIIFIAPPSQERLRALLAKEGKNPKPEELREI--IEKTREMEQNNGHYF-DTAI 643
I++ PS+ L+ ++ ++ +L ++ ++ R + F D +
Sbjct 126 EGALPEKTIYLDVPSELGLKRIMTHRTEDVDRLDLEQLDFHQRVRSAYLDLAKKFPDRIV 185
Query 644 VNS---DLDKAYQELLRLINKL 662
V +LD ++++ +++++
Sbjct 186 VIDASQELDDVKRDVIEVLDQI 207
>sp|Q91YE8|SYNP2_MOUSE Synaptopodin-2 OS=Mus musculus OX=10090
GN=Synpo2 PE=1 SV=2
Length=1087
Score = 42.7 bits (99), Expect = 0.014, Method: Composition-based stats.
Identities = 18/77 (23%), Positives = 29/77 (38%), Gaps = 1/77 (1%)
Query 271 VRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTF 330
+ E + +++I A SG L EGDEV+ ING EV L+ + +L
Sbjct 24 GKEEQQPLQVAKIRSQSKASGSG-LREGDEVVSINGNPCADLTYPEVIKLMEGITDSLHL 82
Query 331 VLIPSQQIKPPPAKETV 347
++
Sbjct 83 LVKRPSSGTSETLDSES 99
>sp|W6RTA4|CLA1_CAEEL Protein clarinet OS=Caenorhabditis elegans
OX=6239 GN=cla-1 PE=1 SV=2
Length=8922
Score = 42.7 bits (99), Expect = 0.014, Method: Composition-based stats.
Identities = 28/161 (17%), Positives = 59/161 (37%), Gaps = 15/161 (9%)
Query 293 GLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKA 352
G + GDEV+E NGI +RGK EV +++ HG + V+ + ++
Sbjct 8618 GQIKIGDEVVEWNGILLRGKTFEEVERIVNKSHGEIEMVIRT------YKNPSSGVYDTL 8671
Query 353 HFDYDPSDDPYVPCRELGLSFQK------GDILH---VISQEDPNWWQAYREGDEDNQPL 403
+ + D P R + + +LH + Q D +++ +
Sbjct 8672 PLNRNTMRDDLSPDRVPPVPMHRINGINNNSVLHHHTLSDSSCHGHIQVSLGYDGNSRLV 8731
Query 404 AGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKK 444
A ++ + + + ++ K G+ K+ +
Sbjct 8732 AKIIRARGLKSRDQSRSAPNPFVKVYLLPGRKVSHKRRTRF 8772
>sp|P34092|MYOB_DICDI Myosin IB heavy chain OS=Dictyostelium discoideum
OX=44689 GN=myoB PE=1 SV=2
Length=1111
Score = 42.7 bits (99), Expect = 0.014, Method: Composition-based stats.
Identities = 24/86 (28%), Positives = 34/86 (40%), Gaps = 19/86 (22%)
Query 328 LTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDP 387
L V P+ Q P AK A +DYD S LSF++GDI+ ++ +++
Sbjct 1043 LPTVAKPAPQPSRPTAK-------ALYDYDASSTDE-------LSFKEGDIIFIVQKDNG 1088
Query 388 NWWQAYREGDEDNQPLAGLVPGKSFQ 413
W Q E G P Q
Sbjct 1089 GWTQG-----ELKSGQKGWAPTNYLQ 1109
>sp|Q1LU61|AROK_BAUCH Shikimate kinase OS=Baumannia cicadellinicola
subsp. Homalodisca coagulata OX=374463 GN=aroK PE=3 SV=1
Length=173
Score = 40.8 bits (94), Expect = 0.014, Method: Composition-based stats.
Identities = 31/168 (18%), Positives = 60/168 (36%), Gaps = 17/168 (10%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQ-----EVAGRDYHFVSR 533
KR I LIGP G++ + ++L + F + R +V G D F SR
Sbjct 4 KRNIFLIGPMGAGKSTIGRQLAQQLNMEFFDSDQEIERLTGADIGWVFDVEGED-GFRSR 62
Query 534 QA--FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLS--LRTQSLKTLRNSD 589
+ + ++ S ++ ++ G + L + Q ++T R+
Sbjct 63 EEKVINELTEKQGIVL-ATGGGSIK--SRETRNRLSARGVVIYLDTTIEKQLVRTKRDKK 119
Query 590 LKPYIIFIAPPSQERLRALLAKEGK--NPKPEELREIIEKTREMEQNN 635
I PS+E L AL + + E++ ++ +
Sbjct 120 RPLLQAKI--PSREVLEALARERNPLYEEIADITIRANEQSAKVVAYH 165
>sp|Q8I1C0|SH3G3_DROPS Endophilin-A OS=Drosophila pseudoobscura
pseudoobscura OX=46245 GN=EndoA PE=3 SV=1
Length=369
Score = 42.0 bits (97), Expect = 0.014, Method: Composition-based stats.
Identities = 15/73 (21%), Positives = 36/73 (49%), Gaps = 7/73 (10%)
Query 334 PSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAY 393
P++ + P+++ +A +D+DP + L F++ DI+ ++++ D NW++
Sbjct 294 PAKSMAVTPSRQQQPCCQALYDFDPENPGE-------LGFKENDIITLLNRVDDNWYEGA 346
Query 394 REGDEDNQPLAGL 406
G P + +
Sbjct 347 VNGRTGYFPQSYV 359
>sp|B4QZU6|HTRA2_DROSI Serine protease HTRA2, mitochondrial OS=Drosophila
simulans OX=7240 GN=HtrA2 PE=3 SV=1
Length=422
Score = 42.0 bits (97), Expect = 0.014, Method: Composition-based stats.
Identities = 21/63 (33%), Positives = 32/63 (51%), Gaps = 3/63 (5%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
N V++ +++ G A SG L GD V IN EI+ +V+D L+D TL V+
Sbjct 350 NLTHGVLVWKVIVGSPAH-SGGLQPGDIVTHINKKEIKNSS--DVYDALADNSKTLDIVI 406
Query 333 IPS 335
+
Sbjct 407 LRG 409
>sp|P0DKH6|RPS6R_ARATH Disease resistance protein RPS6 OS=Arabidopsis
thaliana OX=3702 GN=RPS6 PE=1 SV=1
Length=1127
Score = 42.4 bits (98), Expect = 0.015, Method: Composition-based stats.
Identities = 14/62 (23%), Positives = 29/62 (47%), Gaps = 5/62 (8%)
Query 455 NDDYDNEEILTYEE-----MSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFAS 509
+ D E+++ E+ SL H + R + + GP G+ + + L ++ +F S
Sbjct 179 SPSNDFEDLVGIEDHITKMSSLLHLESEEVRMVGIWGPSGIGKTTISRALFSRLSCQFQS 238
Query 510 AV 511
+V
Sbjct 239 SV 240
>sp|Q54FG5|GACJJ_DICDI Rho GTPase-activating protein gacJJ OS=Dictyostelium
discoideum OX=44689 GN=gacJJ PE=3 SV=1
Length=873
Score = 42.4 bits (98), Expect = 0.015, Method: Composition-based stats.
Identities = 16/63 (25%), Positives = 26/63 (41%), Gaps = 0/63 (0%)
Query 344 KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPL 403
E I K+ ++Y +DD + L F KG + V Q WW +G + P
Sbjct 627 PEQKILAKSLYEYAGNDDGTTSEDDKDLLFPKGATIKVTQQGTDGWWTGEYQGKQGKFPA 686
Query 404 AGL 406
+ +
Sbjct 687 SYV 689
>sp|Q06187|BTK_HUMAN Tyrosine-protein kinase BTK OS=Homo sapiens
OX=9606 GN=BTK PE=1 SV=3
Length=659
Score = 42.4 bits (98), Expect = 0.015, Method: Composition-based stats.
Identities = 21/109 (19%), Positives = 43/109 (39%), Gaps = 12/109 (11%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
V A +DY P + L +KGD ++ + + WW+A D G +P
Sbjct 219 VVALYDYMPMNAND-------LQLRKGDEYFILEESNLPWWRAR-----DKNGQEGYIPS 266
Query 410 KSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDY 458
+ ++++ K +S K+ K+ ++ +++K Y
Sbjct 267 NYVTEAEDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKAGKY 315
>sp|P16333|NCK1_HUMAN SH2/SH3 adapter protein NCK1 OS=Homo sapiens
OX=9606 GN=NCK1 PE=1 SV=1
Length=377
Score = 42.0 bits (97), Expect = 0.016, Method: Composition-based stats.
Identities = 33/146 (23%), Positives = 56/146 (38%), Gaps = 29/146 (20%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ--EDPNWWQAYREGDEDNQPLAGLV 407
V+A + + S+D L+F+KGD++ VI + DP WW+ + + GLV
Sbjct 195 VQALYPFSSSNDEE-------LNFEKGDVMDVIEKPENDPEWWKCRKING-----MVGLV 242
Query 408 PGKSF-QQQREAMKQTIEEDK------EPEKSGKL-----WCAKKNKKKRKKVLYNANKN 455
P Q + +E P +GK + K + + + L
Sbjct 243 PKNYVTVMQNNPLTSGLEPSPPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERGHE 302
Query 456 DDY---DNEEILTYEEMSLYHQPANR 478
D+ D+E +SL Q N+
Sbjct 303 GDFLIRDSESSPNDFSVSLKAQGKNK 328
>sp|O14259|SFP47_SCHPO Ubp4-interactor sfp47 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=sfp47 PE=1
SV=2
Length=415
Score = 42.0 bits (97), Expect = 0.016, Method: Composition-based stats.
Identities = 11/66 (17%), Positives = 23/66 (35%), Gaps = 9/66 (14%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+V+A + Y + + D L V++++ WW+ GL P
Sbjct 356 YVRALYAYKATLPSEI-------DLNVDDTLVVLNRQKDGWWKGLVVSPT--VGRIGLFP 406
Query 409 GKSFQQ 414
++
Sbjct 407 SNYIEE 412
>sp|P18584|DEGPL_CHLTR Probable periplasmic serine endoprotease
DegP-like OS=Chlamydia trachomatis (strain D/UW-3/Cx) OX=272561
GN=htrA PE=3 SV=2
Length=497
Score = 42.0 bits (97), Expect = 0.016, Method: Composition-based stats.
Identities = 21/102 (21%), Positives = 41/102 (40%), Gaps = 10/102 (10%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
++ +++ +VKG AEK+GL E D ++ NG E+ L + +
Sbjct 320 EKVYGALVTDVVKGSPAEKAGLRQE-DVIVAYNGKEVESLSALRNAISLMMPGTRVVLKI 378
Query 333 IPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQ 374
+ + P T I P++D +++G+ Q
Sbjct 379 VREGKTIEIPVTVTQI---------PTEDGVSALQKMGVRVQ 411
>sp|Q1AAU6|ASAP1_RAT Arf-GAP with SH3 domain, ANK repeat and PH
domain-containing protein 1 OS=Rattus norvegicus OX=10116
GN=Asap1 PE=1 SV=2
Length=1144
Score = 42.4 bits (98), Expect = 0.017, Method: Composition-based stats.
Identities = 44/221 (20%), Positives = 84/221 (38%), Gaps = 25/221 (11%)
Query 197 LKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEM--QLEPITDERVYESIGQYGGETV 254
+ P ++ +L+ L P + L ++A + +L P E +
Sbjct 931 IPPETFQKSSQLSELPQKPPLGDLPPKPMELAPKPQIGELPPKPGELPPKPQLGDLPPKP 990
Query 255 KIVRIE---KARDIP----LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
++ + + +D+P LG + S + +++ +E + H GD L N
Sbjct 991 QLSDLPPKPQMKDLPPKPQLGDLLAKSQASDLSAKVQP--PSEVTQRSHTGD--LSPNVQ 1046
Query 308 EIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCR 367
R + + +D+ TL +P + K K V VK +D +D
Sbjct 1047 S-RDAIQKQASEDSNDLTPTLPETPVPLPR-KINTGKNKVRRVKTIYDCQADNDDE---- 1100
Query 368 ELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
L+F +G+++ V +ED WW + EG G+ P
Sbjct 1101 ---LTFIEGEVIIVTGEEDQEWWIGHIEGQP---ERKGVFP 1135
>sp|Q8I190|SH3G3_DROVI Endophilin-A OS=Drosophila virilis OX=7244
GN=EndoA PE=3 SV=1
Length=369
Score = 42.0 bits (97), Expect = 0.017, Method: Composition-based stats.
Identities = 15/73 (21%), Positives = 35/73 (48%), Gaps = 7/73 (10%)
Query 334 PSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAY 393
P++ + P ++ +A +D+DP + L F++ DI+ ++++ D NW++
Sbjct 294 PAKSMAVTPNRQQQPCCQALYDFDPENPGE-------LGFKENDIITLLNRVDDNWYEGA 346
Query 394 REGDEDNQPLAGL 406
G P + +
Sbjct 347 VNGRTGYFPQSYV 359
>sp|P53281|LSB1_YEAST LAS seventeen-binding protein 1 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=LSB1
PE=1 SV=1
Length=241
Score = 41.2 bits (95), Expect = 0.017, Method: Composition-based stats.
Identities = 18/125 (14%), Positives = 43/125 (34%), Gaps = 21/125 (17%)
Query 339 KPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDE 398
+ P +T +V+A +D++ D LS + GD + V+ + P+W++
Sbjct 47 RSPQNADTEEYVEALYDFEAQQDGD-------LSLKTGDKIQVLEKISPDWYRGK----- 94
Query 399 DNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDY 458
+ G+ P + + + E S + + Y
Sbjct 95 -SNNKIGIFPANYV--KPAFTRSASPKSAEAASSSTV------SRPSVPPPSYEPAASQY 145
Query 459 DNEEI 463
++++
Sbjct 146 PSQQV 150
>sp|B9K8E0|DER_THENN GTPase Der OS=Thermotoga neapolitana (strain
ATCC 49049 / DSM 4359 / NBRC 107923 / NS-E) OX=309803 GN=der
PE=3 SV=1
Length=439
Score = 42.0 bits (97), Expect = 0.017, Method: Composition-based stats.
Identities = 29/125 (23%), Positives = 46/125 (37%), Gaps = 18/125 (14%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV--AGRDYHFVSRQAFEAD 539
I ++G N G++ L ++NKE+ S +P TTR D EV G+ Y FV
Sbjct 183 IAIVGRPNVGKSTLFNAILNKER-ALVSPIPGTTRDPVDDEVFIDGKKYIFVDTAGLRRK 241
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKT--------LRNSDLK 591
IE E Y T V + + ++ TQ + +
Sbjct 242 SR----IEPKTVE--RYSTYRV-VESIERADVAVIVLDATQGITRQDQRIAGLVERKGKA 294
Query 592 PYIIF 596
++F
Sbjct 295 SVVVF 299
>sp|Q8ZH59|RSEP_YERPE Protease RseP OS=Yersinia pestis OX=632
GN=rseP PE=3 SV=1
Length=451
Score = 42.0 bits (97), Expect = 0.018, Method: Composition-based stats.
Identities = 40/228 (18%), Positives = 77/228 (34%), Gaps = 28/228 (12%)
Query 194 QTVLKPVHHKEGQELTAL--LNTPHIQAL-LLAHDKVAEQEMQLEPITDERVYESIGQYG 250
Q++ + G EL ++ + TP ++ L ++ +++MQ+
Sbjct 137 QSIAAQANISSGMELKSVDGIETPDWDSVRLALISRIGDKQMQVGVAPFGSDNVVEKTL- 195
Query 251 GETVKIVRIEKARDIP---LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 307
++ + E + P LG R +++ + G AA+K+G L GD ++++NG
Sbjct 196 --DLRQWQFEPDKQDPVVALGIIPRGPQIESVLAEVQPGSAAQKAG-LQAGDRIVKVNGQ 252
Query 308 ----------EIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYD 357
++R + + L+ LIP + E
Sbjct 253 LLDRWQTFVLQVRDNPGQPLVLDIERESTPLSLTLIPDTKSVGENRSEG--FAGVVPKVI 310
Query 358 PSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAG 405
P D Y R+ G F V D W + + G
Sbjct 311 PLPDEYKTIRQYG-PFT-----AVYQAGDKTWQLMRLTVSMLGKLITG 352
>sp|P50545|HCK_RAT Tyrosine-protein kinase HCK OS=Rattus norvegicus
OX=10116 GN=Hck PE=1 SV=4
Length=524
Score = 42.0 bits (97), Expect = 0.019, Method: Composition-based stats.
Identities = 48/242 (20%), Positives = 77/242 (32%), Gaps = 52/242 (21%)
Query 331 VLIPSQQIKPPPA----KETVIHVKAHFDYDP--SDDPYVPCRELGLSFQKGDILHVISQ 384
L P+ PP E I V A +DY+ +D LSFQKGD + V+ +
Sbjct 59 KLGPNSINSLPPGVVEGSEDTIVV-ALYDYEAIHRED---------LSFQKGDQMVVLEE 108
Query 385 EDPNWWQAYREGDEDNQPLAGLVPGKSFQ-----QQREAMKQTIEEDKEPE----KSGKL 435
WW+A G +P + E + I L
Sbjct 109 S-GEWWKAR----SLATKKEGYIPSNYVARVNSLETEEWFFKGISRKDAERHLLAPGNML 163
Query 436 WCAKKNKKKRKKVLYNAN-------KNDDYDNEEILTYEEMSLYHQP-ANRKRPIILIGP 487
+ K Y+ + D + +I T + Y P + L+
Sbjct 164 GSFMIRDSETTKGSYSLSVRDFDPQHGDTVKHYKIRTLDSGGFYISPRSTFSSLQELVVH 223
Query 488 QNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ--AFEADIAAGKF 545
G++ L Q+L S + Q+ +D + R+ E + AG+F
Sbjct 224 YKKGKDGLCQKL------------SVPCVSPKPQKPWEKDAWEIPRESLQMEKKLGAGQF 271
Query 546 IE 547
E
Sbjct 272 GE 273
>sp|A4FU49|SH321_HUMAN SH3 domain-containing protein 21 OS=Homo
sapiens OX=9606 GN=SH3D21 PE=2 SV=2
Length=640
Score = 42.0 bits (97), Expect = 0.019, Method: Composition-based stats.
Identities = 22/117 (19%), Positives = 43/117 (37%), Gaps = 11/117 (9%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ--EDPNWWQAYREGDEDNQPLAGLVP 408
+ FDY P L+ ++GD++ V+S+ ED WW+ +G P ++P
Sbjct 71 RVLFDYQPEAPDE-------LALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFVLP 123
Query 409 GKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILT 465
++ ++ + + P K K K + KK+ +
Sbjct 124 PPPI--KKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPSKAKTSRTPS 178
>sp|Q63767|BCAR1_RAT Breast cancer anti-estrogen resistance protein
1 OS=Rattus norvegicus OX=10116 GN=Bcar1 PE=1 SV=1
Length=968
Score = 42.0 bits (97), Expect = 0.019, Method: Composition-based stats.
Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 16/77 (21%)
Query 339 KPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQED---PNWWQAYRE 395
KP +++ + KA +D + ++ P LSF+KGDI+ V+ ++ WW
Sbjct 91 KPAASRDKNVLAKALYD-NVAESPD------ELSFRKGDIMTVLERDTQGLDGWWLCSLH 143
Query 396 GDEDNQPLAGLVPGKSF 412
G G+VPG
Sbjct 144 G------RQGIVPGNRL 154
>sp|P72780|HHOA_SYNY3 Putative serine protease HhoA OS=Synechocystis
sp. (strain PCC 6803 / Kazusa) OX=1111708 GN=hhoA PE=1
SV=1
Length=394
Score = 41.6 bits (96), Expect = 0.020, Method: Composition-based stats.
Identities = 13/64 (20%), Positives = 32/64 (50%), Gaps = 1/64 (2%)
Query 274 EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
E+D +++ R++ G AE++G + GD ++ ++G I + + ++ L L+
Sbjct 316 EVDGILVMRVLPGTPAERAG-IRRGDVIVAVDGTPISDGARLQRIVEQAGLNKALKLDLL 374
Query 334 PSQQ 337
+
Sbjct 375 RGDR 378
>sp|Q8YCG3|FBPC_BRUME Fe(3+) ions import ATP-binding protein FbpC
OS=Brucella melitensis biotype 1 (strain 16M / ATCC 23456
/ NCTC 10094) OX=224914 GN=fbpC PE=3 SV=1
Length=353
Score = 41.6 bits (96), Expect = 0.020, Method: Composition-based stats.
Identities = 26/219 (12%), Positives = 56/219 (26%), Gaps = 40/219 (18%)
Query 464 LTYEEMSL----------YHQPANRKRPIILIGPQNCGQNELRQRLMN-KEKDRFASAVP 512
+T+E ++ + L+G CG+ + L + +
Sbjct 9 VTFENVTKKFGNFTALPNLSLTVEPGTLVTLLGLSGCGKTTTLRLLAGLEHPTSGRILIG 68
Query 513 HTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKI 572
+ F S F + +E+ + G + R+ G
Sbjct 69 GKDVTNLPANERDVSMVFQSYALFPHMTS----LENVAYGLESSGFKKNEARERAEEGLK 124
Query 573 CL--------LSLRTQSLKTLRNSDLKPYI----IFIAPPSQERLRALLAKEGKNPKPEE 620
+ L + R + + + + + L A L + + E
Sbjct 125 LVGLGGMGHRLPAELSGGQQQRVAVARALVLEPQVLLLDEPLSNLDARLRRRVRTEIREL 184
Query 621 LREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLI 659
+ + F V D D+A +I
Sbjct 185 QQRLG-------------FTAVYVTHDQDEALAVSDTII 210
>sp|Q9PW72|PDLI4_CHICK PDZ and LIM domain protein 4 OS=Gallus
gallus OX=9031 GN=PDLIM4 PE=1 SV=1
Length=330
Score = 41.6 bits (96), Expect = 0.020, Method: Composition-based stats.
Identities = 17/87 (20%), Positives = 27/87 (31%), Gaps = 2/87 (2%)
Query 257 VRIEKARDIPLGATVRNEMD-SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVN 315
V + + + ISRI G A L GD +L ING
Sbjct 5 VALRGPSPWGFRLVGGKDFSTPLTISRINPGSKAAL-ANLCPGDIILAINGESTEAMTHL 63
Query 316 EVFDLLSDMHGTLTFVLIPSQQIKPPP 342
E + + L + +++ P
Sbjct 64 EAQNKIKACVEQLLLSVSRAEERSWSP 90
>sp|P59047|NALP5_HUMAN NACHT, LRR and PYD domains-containing protein
5 OS=Homo sapiens OX=9606 GN=NLRP5 PE=1 SV=2
Length=1200
Score = 42.0 bits (97), Expect = 0.020, Method: Composition-based stats.
Identities = 24/172 (14%), Positives = 53/172 (31%), Gaps = 28/172 (16%)
Query 413 QQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLY 472
+Q A EE + K ++ + + +N D E+ T
Sbjct 213 MEQEGATAAETEEQGHGGDTWDYKSHVMTKFAEEEDVRRSFENTAADWPEMQTLAGAFDS 272
Query 473 HQPANRKRPIILIGPQNCGQNELRQR--LMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ R R ++L G G++ L +R L + + + F
Sbjct 273 DRWGFRPRTVVLHGKSGIGKSALARRIVLCWAQGGLYQGMFSYV--------------FF 318
Query 531 VSRQAFEADIAAG--KFI--EHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
+ + + + +FI E + S V ++++ + L +
Sbjct 319 LPVREMQRKKESSVTEFISREWPD--------SQAPVTEIMSRPERLLFIID 362
>sp|B3P3J9|HTRA2_DROER Serine protease HTRA2, mitochondrial OS=Drosophila
erecta OX=7220 GN=HtrA2 PE=3 SV=1
Length=422
Score = 41.6 bits (96), Expect = 0.021, Method: Composition-based stats.
Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 3/64 (5%)
Query 272 RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV 331
N V++ +++ G A SG L GD V IN EI+ +V+D L+D L V
Sbjct 349 SNLTHGVLVWKVIVGSPAH-SGGLQPGDIVTHINKKEIKNSS--DVYDALADNSKNLDIV 405
Query 332 LIPS 335
++
Sbjct 406 ILRG 409
>sp|Q7TSG5|SH321_MOUSE SH3 domain-containing protein 21 OS=Mus
musculus OX=10090 GN=Sh3d21 PE=1 SV=1
Length=549
Score = 42.0 bits (97), Expect = 0.021, Method: Composition-based stats.
Identities = 25/117 (21%), Positives = 44/117 (38%), Gaps = 11/117 (9%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ--EDPNWWQAYREGDEDNQPLAGLVP 408
+ FDY P L+ QKGD++ V+ + ED WW+ +G P ++P
Sbjct 71 RVLFDYQPEAPDE-------LALQKGDLVKVLRKTTEDKGWWEGECQGRRGVFPDNFVIP 123
Query 409 GKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILT 465
++ ++ I + P K K K + KK+ A+ +
Sbjct 124 PPPI--RKLIPRKIISRESAPIKETKKLMPKSSLPTVKKLAAAASAPGRAKTLSTPS 178
>sp|Q4A6Z8|KTHY_MYCS5 Thymidylate kinase OS=Mycoplasmopsis synoviae
(strain 53) OX=262723 GN=tmk PE=3 SV=1
Length=214
Score = 40.4 bits (93), Expect = 0.022, Method: Composition-based stats.
Identities = 16/94 (17%), Positives = 27/94 (29%), Gaps = 14/94 (15%)
Query 489 NCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEH 548
G+ + L+ K KD F TR +++ + I +E
Sbjct 10 GSGKTTVINELLKKLKDNFKFLDYVLTREPGGKDI-------KESEKIREMILDSD-LEF 61
Query 549 GEFEKN-LYGTSI-----DSVRQVINSGKICLLS 576
+ LY TS + + KI
Sbjct 62 SPITEALLYTTSRRIHIDKVILPALAQNKIVFCD 95
>sp|P08631|HCK_HUMAN Tyrosine-protein kinase HCK OS=Homo sapiens
OX=9606 GN=HCK PE=1 SV=5
Length=526
Score = 41.6 bits (96), Expect = 0.022, Method: Composition-based stats.
Identities = 22/94 (23%), Positives = 30/94 (32%), Gaps = 16/94 (17%)
Query 324 MHGTLTFVLIPSQQIKPPPA----KETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDIL 379
T T P+ P I V A +DY+ LSFQKGD +
Sbjct 53 PDPTSTIKPGPNSHNSNTPGIREAGSEDIIVVALYDYEAIHHED-------LSFQKGDQM 105
Query 380 HVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
V+ + WW+A G +P
Sbjct 106 VVLEES-GEWWKAR----SLATRKEGYIPSNYVA 134
>sp|A1SWH9|UGPC_PSYIN sn-glycerol-3-phosphate import ATP-binding
protein UgpC OS=Psychromonas ingrahamii (strain DSM 17664
/ CCUG 51855 / 37) OX=357804 GN=ugpC PE=3 SV=1
Length=373
Score = 41.6 bits (96), Expect = 0.022, Method: Composition-based stats.
Identities = 23/179 (13%), Positives = 54/179 (30%), Gaps = 29/179 (16%)
Query 466 YEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAG 525
Y+ + ++L+GP CG++ L + + + T + +
Sbjct 17 YQAVHKLSLNIEDGEMVVLVGPSGCGKSTLLRMIA---------GLEEITSGKLKIDDCL 67
Query 526 RDYHFVSRQAFEADIAAGKFIEHGEFEKNL-YG-----TSIDSVRQVINSGKICLLSLR- 578
+ S + H N+ YG T +++++N +L +
Sbjct 68 VNNLEPSERDIAMVFQNYALYPHMSVYDNMAYGLRNRKTPKADIQRIVN-DTAEMLEIDH 126
Query 579 --------TQSLKTLRNSDLKPYI----IFIAPPSQERLRALLAKEGKNPKPEELREII 625
+ R + + + IF+ L A L + + + R +
Sbjct 127 LLERKPKELSGGQRQRVAMGRAIVRKPKIFLFDEPLSNLDAKLRVQMRLQIKKLQRRLA 185
>sp|D1ZRK4|SHO1_SORMK High osmolarity signaling protein SHO1 OS=Sordaria
macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346)
/ K-hell) OX=771870 GN=SHO1 PE=3 SV=1
Length=320
Score = 41.2 bits (95), Expect = 0.022, Method: Composition-based stats.
Identities = 19/82 (23%), Positives = 29/82 (35%), Gaps = 11/82 (13%)
Query 331 VLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW 390
+ + P E KA F Y+ + D +SF K ++L + WW
Sbjct 247 KPPQGTEGEIVPPTEYPYRAKAIFSYEANPDDA-----NEISFSKHEVLEISDVS-GRWW 300
Query 391 QAYREGDEDNQPLAGLVPGKSF 412
QA +E E G+ P
Sbjct 301 QARKETGE-----TGIAPSNYL 317
>sp|Q2P2T5|DER_XANOM GTPase Der OS=Xanthomonas oryzae pv. oryzae
(strain MAFF 311018) OX=342109 GN=der PE=3 SV=1
Length=465
Score = 41.6 bits (96), Expect = 0.023, Method: Composition-based stats.
Identities = 39/200 (20%), Positives = 70/200 (35%), Gaps = 39/200 (20%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRS--RRDQEVAGRDYHFVSRQAFEAD 539
I +G N G++ L RL+ +E+ AS VP TTR D E GR Y +
Sbjct 181 IAFVGRPNVGKSTLVNRLLGEER-MIASEVPGTTRDSIAVDLERDGRQYRLIDTAGLRRR 239
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVR-------------------QVINSGKICLLSLR-T 579
+ +E K L V ++++G+ ++++
Sbjct 240 GKVEEAVEKFSAFKTLQAIERCQVAVLMLDATEGVTDQDATILGAILDAGRALVVAINKW 299
Query 580 QSLKTLRNSDLKPYII----FIAPPSQERLRAL--LAKEGKNPKPEELREIIEKTREMEQ 633
+ + + + F+ S + L G +RE+ +
Sbjct 300 DGQSDYQRAQAEDLLSRKLGFV---SWAEAVRISALHGSG-------MRELFQAIHRAHA 349
Query 634 NNGHYFDTAIVNSDLDKAYQ 653
+ H F T+ VN L+ AY+
Sbjct 350 SATHEFSTSEVNQALEIAYE 369
>sp|Q99962|SH3G2_HUMAN Endophilin-A1 OS=Homo sapiens OX=9606 GN=SH3GL2
PE=1 SV=1
Length=352
Score = 41.2 bits (95), Expect = 0.024, Method: Composition-based stats.
Identities = 15/56 (27%), Positives = 29/56 (52%), Gaps = 7/56 (13%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGL 406
+A +D++P + E L F++GDI+ + +Q D NW++ G P+ +
Sbjct 296 RALYDFEPEN-------EGELGFKEGDIITLTNQIDENWYEGMLHGHSGFFPINYV 344
>sp|Q8TEC5|SH3R2_HUMAN E3 ubiquitin-protein ligase SH3RF2 OS=Homo
sapiens OX=9606 GN=SH3RF2 PE=1 SV=3
Length=729
Score = 41.6 bits (96), Expect = 0.024, Method: Composition-based stats.
Identities = 34/210 (16%), Positives = 68/210 (32%), Gaps = 40/210 (19%)
Query 297 EGDEVL------------EINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAK 344
+GD +L EINGI G +++ + +PPP
Sbjct 148 KGDIILLRRQLDENWYQGEINGIS--GNFPASSVEVIKQLP-------------QPPPL- 191
Query 345 ETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLA 404
+A +++D ++ L+F K DI+ VIS+ D NW + P+
Sbjct 192 -----CRALYNFDLRGKDKSENQDC-LTFLKDDIITVISRVDENWAEGKLGDKVGIFPIL 245
Query 405 GLVPG---KSFQQQ---REAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDY 458
+ P + ++ R++ + G ++ R+KV +
Sbjct 246 FVEPNLTARHLLEKNKGRQSSRTKNLSLVSSSSRGNTSTLRRGPGSRRKVPGQFSITTAL 305
Query 459 DNEEILTYEEMSLYHQPANRKRPIILIGPQ 488
+ + + + + I P
Sbjct 306 NTLNRMVHSPSGRHMVEISTPVLISSSNPS 335
Score = 39.7 bits (91), Expect = 0.099, Method: Composition-based stats.
Identities = 24/91 (26%), Positives = 34/91 (37%), Gaps = 11/91 (12%)
Query 325 HGTLTFVLIPSQQIKPPPAKETVIH----VKAHFDYDPSDDPYVPCRELG-----LSFQK 375
GT+T + P + + V+ H D P C G L F K
Sbjct 91 PGTMTLQDGRKSRTNPRRLQASPFRLVPNVRIHMDGVPRAKAL--CNYRGQNPGDLRFNK 148
Query 376 GDILHVISQEDPNWWQAYREGDEDNQPLAGL 406
GDI+ + Q D NW+Q G N P + +
Sbjct 149 GDIILLRRQLDENWYQGEINGISGNFPASSV 179
>sp|Q9Z3I3|NODI_BRASS Nod factor export ATP-binding protein I
OS=Bradyrhizobium sp. (strain SNU001) OX=84640 GN=nodI PE=3
SV=1
Length=305
Score = 41.2 bits (95), Expect = 0.024, Method: Composition-based stats.
Identities = 16/90 (18%), Positives = 28/90 (31%), Gaps = 5/90 (6%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKE-KDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
R L+GP G++ + + L+ DR V R + G F
Sbjct 32 RGECFGLLGPNGAGKSTIARMLLGMIWPDRGKITVLDEPVPSRARARRGVG----VVPQF 87
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQV 566
+ E+ +G S ++ V
Sbjct 88 DNLEPEFTVRENLLVFGRYFGMSARTIEAV 117
>sp|Q4WUG9|SHO1_ASPFU High osmolarity signaling protein sho1 OS=Aspergillus
fumigatus (strain ATCC MYA-4609 / CBS 101355 /
FGSC A1100 / Af293) OX=330879 GN=sho1 PE=3 SV=2
Length=288
Score = 40.8 bits (94), Expect = 0.025, Method: Composition-based stats.
Identities = 22/78 (28%), Positives = 30/78 (38%), Gaps = 11/78 (14%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
S Q + PP E KA + YD + P +SF K +IL V WWQA +
Sbjct 219 SGQDEVPPPTEYPYKAKAIYSYDAN-----PEDANEISFSKHEILEVSDVS-GRWWQARK 272
Query 395 EGDEDNQPLAGLVPGKSF 412
+ G+ P
Sbjct 273 -----SNGETGIAPSNYL 285
>sp|B0Y3Z4|SHO1_ASPFC High osmolarity signaling protein sho1 OS=Aspergillus
fumigatus (strain CBS 144.89 / FGSC A1163 / CEA10)
OX=451804 GN=sho1 PE=3 SV=2
Length=288
Score = 40.8 bits (94), Expect = 0.025, Method: Composition-based stats.
Identities = 22/78 (28%), Positives = 30/78 (38%), Gaps = 11/78 (14%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
S Q + PP E KA + YD + P +SF K +IL V WWQA +
Sbjct 219 SGQDEVPPPTEYPYKAKAIYSYDAN-----PEDANEISFSKHEILEVSDVS-GRWWQARK 272
Query 395 EGDEDNQPLAGLVPGKSF 412
+ G+ P
Sbjct 273 -----SNGETGIAPSNYL 285
>sp|Q95KR7|LCK_SAISC Proto-oncogene tyrosine-protein kinase LCK
OS=Saimiri sciureus OX=9521 GN=LCK PE=1 SV=3
Length=509
Score = 41.6 bits (96), Expect = 0.025, Method: Composition-based stats.
Identities = 45/273 (16%), Positives = 92/273 (34%), Gaps = 37/273 (14%)
Query 307 IEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPC 366
+ + GK LL + L+ + PP + V A Y+PS D
Sbjct 28 VPLDGK-----ATLLFRNGSEVRDPLVRYEGSNPPASPLQDNLVIALHSYEPSHDGD--- 79
Query 367 RELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ-----------Q 415
L F+KG+ L ++ Q WW+A G VP + +
Sbjct 80 ----LGFEKGEHLRILEQN-GEWWKA----QSLTTGQEGFVPFNFVAKANSLEPEPWFFK 130
Query 416 REAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQP 475
+ K + P + + + + + ++ D + E++ + ++
Sbjct 131 NLSRKDAERQLLAPGNTHGSF-LIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNG 189
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
P I G +EL + D + + ++++ Q+ D V R+
Sbjct 190 GFYISPRITFS----GLHELVRH-YTNASDGLCTRLSRPCQTQKPQKPWWEDEWEVPRET 244
Query 536 FE--ADIAAGKFIE-HGEFEKNLYGTSIDSVRQ 565
+ + AG+F E + ++ S++Q
Sbjct 245 LKLVERLGAGQFGEVWMGYYNEHTKVAVKSLKQ 277
>sp|Q8IXQ8|PDZD9_HUMAN PDZ domain-containing protein 9 OS=Homo
sapiens OX=9606 GN=PDZD9 PE=2 SV=2
Length=264
Score = 40.8 bits (94), Expect = 0.026, Method: Composition-based stats.
Identities = 16/86 (19%), Positives = 33/86 (38%), Gaps = 0/86 (0%)
Query 264 DIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD 323
+ LG + + I+ +++ GAA G L GD ++ + + G + E LL
Sbjct 37 SLGLGLIIIQHGPYLQITHLIRKGAAANDGKLQPGDVLISVGHANVLGYTLREFLQLLQH 96
Query 324 MHGTLTFVLIPSQQIKPPPAKETVIH 349
+ + + P + I+
Sbjct 97 ITIGTVLQIKVYRDFINIPEEWQEIY 122
>sp|Q06449|PIN3_YEAST [PSI+] inducibility protein 3 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=PIN3
PE=1 SV=1
Length=215
Score = 40.4 bits (93), Expect = 0.026, Method: Composition-based stats.
Identities = 13/60 (22%), Positives = 25/60 (42%), Gaps = 7/60 (12%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+V+A + +DP D L + GD + ++ + P W++ G P + P
Sbjct 58 YVEALYQFDPQQDGD-------LGLKPGDKVQLLEKLSPEWYKGSCNGRTGIFPANYVKP 110
>sp|Q9FI14|TAO1_ARATH Disease resistance protein TAO1 OS=Arabidopsis
thaliana OX=3702 GN=TAO1 PE=3 SV=1
Length=1187
Score = 41.6 bits (96), Expect = 0.026, Method: Composition-based stats.
Identities = 31/186 (17%), Positives = 51/186 (27%), Gaps = 19/186 (10%)
Query 408 PGKSFQQQREAMKQTI----EEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEI 463
P + Q+ ++A+ E+ + E + + D++ E
Sbjct 159 PEEMVQRWKQALTSAANILGEDSRNWENEADMIIKISKDVSDVLSFTPSKDFDEFVGIEA 218
Query 464 LTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAV---PHTTRSRRD 520
T E SL R I + GP G+ + + L NK +F R R
Sbjct 219 HTTEITSLLQLDLEEVRMIGIWGPAGIGKTTISRVLYNKLFHQFQLGAIIDNIKVRYPRP 278
Query 521 QEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSL-RT 579
+ ++ I + V Q K LL L
Sbjct 279 CHDEYSAKLQLQKELLSQMINQKDMV-----------VPHLGVAQERLKDKKVLLVLDDV 327
Query 580 QSLKTL 585
L L
Sbjct 328 DGLVQL 333
>sp|P42683|LCK_CHICK Proto-oncogene tyrosine-protein kinase LCK
OS=Gallus gallus OX=9031 GN=LCK PE=2 SV=2
Length=508
Score = 41.6 bits (96), Expect = 0.026, Method: Composition-based stats.
Identities = 21/101 (21%), Positives = 37/101 (37%), Gaps = 12/101 (12%)
Query 313 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLS 372
D + L + L+ + + PP + V A +DY+P+ D L
Sbjct 28 DPDSKRQQLIRNVSEVRDPLVSYEAMSPPCSPLQDKLVVALYDYEPTHDGD-------LG 80
Query 373 FQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
++G+ L V+ + WW+A GL+P
Sbjct 81 LKQGEKLRVLEES-GEWWRA----QSLTTGQEGLIPHNFVA 116
>sp|Q55669|CTPA_SYNY3 Carboxyl-terminal-processing protease OS=Synechocystis
sp. (strain PCC 6803 / Kazusa) OX=1111708 GN=ctpA
PE=3 SV=1
Length=427
Score = 41.2 bits (95), Expect = 0.026, Method: Composition-based stats.
Identities = 15/80 (19%), Positives = 36/80 (45%), Gaps = 2/80 (3%)
Query 263 RDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLS 322
+ L + E + + I + G AE++G L D++L I+G++ + ++E +
Sbjct 114 SGVGLQININPETNQLEIMAPLAGSPAEEAG-LQPHDQILAIDGVDTQTLSLDEAAARMR 172
Query 323 DMHGT-LTFVLIPSQQIKPP 341
T ++ ++ + P
Sbjct 173 GPKNTKVSLEILSAGTEVPQ 192
>sp|Q8U4K7|PGK2_PYRFU 2-phosphoglycerate kinase OS=Pyrococcus
furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) OX=186497
GN=pgk2 PE=3 SV=1
Length=302
Score = 40.8 bits (94), Expect = 0.026, Method: Composition-based stats.
Identities = 31/217 (14%), Positives = 65/217 (30%), Gaps = 55/217 (25%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
I+L GP G++ + L F + + +EV + +
Sbjct 90 PLIILLGGPTGVGKSTIATELA------FRLGIRSVIGTDTIREVMRK----IITPELLP 139
Query 539 DIAAGKFIEHGEFEKNLYGTSI----------------DSVRQVINSGKICLLSLRTQSL 582
I F+ E + G+ I +++ I G ++ +
Sbjct 140 TIHTSTFLAWKELRGTVTGSPIIAGFESQVNAVAVGVNAVIQRAIKEGLNAIIE----GI 195
Query 583 KTL----RNSDLKPYIIFIAPPSQERLRALLAKEGK-------------NPKPEELREII 625
+ + ++ I S+E L A + + + E +I
Sbjct 196 HLVPGFIKIDYEMAFMYMIVARSREELEARFYERTRYSKRSAQYYISHLDEIMEIQEYLI 255
Query 626 EKTREMEQNNGHYFDTAIVNSDLDKAYQELLR-LINK 661
+K RE I N +L+K ++ ++ K
Sbjct 256 KKAREYRVP-------IIENVELEKTISTIMEDIMEK 285
>sp|O35180|SH3G3_RAT Endophilin-A3 OS=Rattus norvegicus OX=10116
GN=Sh3gl3 PE=1 SV=2
Length=347
Score = 41.2 bits (95), Expect = 0.027, Method: Composition-based stats.
Identities = 16/64 (25%), Positives = 31/64 (48%), Gaps = 10/64 (16%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAG---LV 407
+ +D++P + E L F++GDI+ + +Q D NW++ G+ P+ +V
Sbjct 291 RGLYDFEPEN-------EGELGFKEGDIITLTNQIDENWYEGMLRGESGFFPINYVEVIV 343
Query 408 PGKS 411
P
Sbjct 344 PLPR 347
>sp|B4PST0|HTRA2_DROYA Serine protease HTRA2, mitochondrial OS=Drosophila
yakuba OX=7245 GN=HtrA2 PE=3 SV=1
Length=422
Score = 41.2 bits (95), Expect = 0.027, Method: Composition-based stats.
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 3/61 (5%)
Query 275 MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIP 334
V++ +++ G A SG L GD V IN EI+ +V+D L+D L V++
Sbjct 352 THGVLVWKVIVGSPAH-SGGLQPGDIVTHINKKEIKNSS--DVYDALADNSKNLDIVILR 408
Query 335 S 335
Sbjct 409 G 409
>sp|P40341|YTA12_YEAST Mitochondrial respiratory chain complexes
assembly protein YTA12 OS=Saccharomyces cerevisiae (strain
ATCC 204508 / S288c) OX=559292 GN=YTA12 PE=1 SV=2
Length=825
Score = 41.6 bits (96), Expect = 0.028, Method: Composition-based stats.
Identities = 25/159 (16%), Positives = 39/159 (25%), Gaps = 35/159 (22%)
Query 388 NWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKK 447
NW +A + +AG++ G K
Sbjct 290 NWAKAMFQILPTVLMIAGII-------WLTRRSAQAAGGSRGGIFGLSRSKAKKFNTETD 342
Query 448 VLYNANKNDDYDNEEILTYEEMSLYHQPANR-------KRPIILIGPQNCGQNELRQRLM 500
V D + E +S +P+ R IL GP G+ L +
Sbjct 343 VKIKFKDVAGCDEAKEEIMEFVSFLKEPSRYEKMGAKIPRGAILSGPPGTGKTLLAKATA 402
Query 501 NKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
+ AG ++FVS F
Sbjct 403 GE---------------------AGVPFYFVSGSEFVEM 420
>sp|P43603|LSB3_YEAST LAS seventeen-binding protein 3 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=LSB3
PE=1 SV=3
Length=459
Score = 41.2 bits (95), Expect = 0.028, Method: Composition-based stats.
Identities = 12/45 (27%), Positives = 21/45 (47%), Gaps = 8/45 (18%)
Query 371 LSFQKGDILHVISQEDP--NWWQAYREGDEDNQPLAGLVPGKSFQ 413
L F+KGD++ ++ + D +WW G E G+ P +
Sbjct 419 LPFRKGDVITILKKSDSQNDWWTGRVNGRE------GIFPANYVE 457
>sp|A7A261|LSB3_YEAS7 LAS seventeen-binding protein 3 OS=Saccharomyces
cerevisiae (strain YJM789) OX=307796 GN=LSB3 PE=3 SV=2
Length=459
Score = 41.2 bits (95), Expect = 0.028, Method: Composition-based stats.
Identities = 12/45 (27%), Positives = 21/45 (47%), Gaps = 8/45 (18%)
Query 371 LSFQKGDILHVISQEDP--NWWQAYREGDEDNQPLAGLVPGKSFQ 413
L F+KGD++ ++ + D +WW G E G+ P +
Sbjct 419 LPFRKGDVITILKKSDSQNDWWTGRVNGRE------GIFPANYVE 457
>sp|P19706|MYSB_ACACA Myosin heavy chain IB OS=Acanthamoeba castellanii
OX=5755 GN=MIB PE=1 SV=2
Length=1147
Score = 41.6 bits (96), Expect = 0.028, Method: Composition-based stats.
Identities = 18/65 (28%), Positives = 26/65 (40%), Gaps = 13/65 (20%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
VKA +DYD L+F++GD + V ++ WW+ G G VP
Sbjct 1095 VKALYDYDAQTGDE-------LTFKEGDTIIVHQKDPAGWWEGELNGK------RGWVPA 1141
Query 410 KSFQQ 414
Q
Sbjct 1142 NYVQD 1146
>sp|O14136|PEX13_SCHPO Peroxisomal membrane protein pex13 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=pex13 PE=3 SV=1
Length=288
Score = 40.8 bits (94), Expect = 0.028, Method: Composition-based stats.
Identities = 18/68 (26%), Positives = 28/68 (41%), Gaps = 16/68 (24%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDP-----NWWQAYREGDEDNQPL 403
KA +++ S DP V +S +KGDI+ ++S+ D WWQ +
Sbjct 226 FCKADYEFM-SRDPGV-----EMSLKKGDIIAILSKTDTQGNPCEWWQGRK-----RSGE 274
Query 404 AGLVPGKS 411
G P
Sbjct 275 TGWFPSNY 282
>sp|Q62421|SH3G3_MOUSE Endophilin-A3 OS=Mus musculus OX=10090
GN=Sh3gl3 PE=1 SV=1
Length=347
Score = 40.8 bits (94), Expect = 0.029, Method: Composition-based stats.
Identities = 14/56 (25%), Positives = 29/56 (52%), Gaps = 7/56 (13%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGL 406
+ +D++P + E L F++GDI+ + +Q D NW++ G+ P+ +
Sbjct 291 RGLYDFEPEN-------EGELGFKEGDIITLTNQIDENWYEGMLRGESGFFPINYV 339
>sp|P42687|SPK1_GIRTI Tyrosine-protein kinase SPK-1 OS=Girardia
tigrina OX=6162 PE=2 SV=1
Length=497
Score = 41.2 bits (95), Expect = 0.029, Method: Composition-based stats.
Identities = 30/123 (24%), Positives = 50/123 (41%), Gaps = 19/123 (15%)
Query 322 SDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHV 381
S T IP + + PP VKA + Y S D + SF++ +I++V
Sbjct 13 SKNKNTSKCQKIPKKAYEGPP---GSYMVKAKYKYAASGDTDI-------SFEEKEIMYV 62
Query 382 ISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKN 441
+ Q D W + ++ D GLVP +Q + + E + + W A+K+
Sbjct 63 LEQFDEFWLKVVKQKDNKE----GLVPSNYVSKQDGS-----PQSVEAWREIQRWEAEKS 113
Query 442 KKK 444
K
Sbjct 114 LMK 116
>sp|A6VUA4|DEGPL_MARMS Probable periplasmic serine endoprotease
DegP-like OS=Marinomonas sp. (strain MWYL1) OX=400668 GN=Mmwyl1_1102
PE=3 SV=1
Length=469
Score = 41.2 bits (95), Expect = 0.030, Method: Composition-based stats.
Identities = 15/36 (42%), Positives = 21/36 (58%), Gaps = 1/36 (3%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
+ +ISR++ AEK+G L GD +LE NG I
Sbjct 293 NGALISRVLPDSPAEKAG-LKSGDIILEFNGQSIAH 327
>sp|Q3U214|MAST3_MOUSE Microtubule-associated serine/threonine-protein
kinase 3 OS=Mus musculus OX=10090 GN=Mast3 PE=1 SV=3
Length=1321
Score = 41.6 bits (96), Expect = 0.031, Method: Composition-based stats.
Identities = 21/111 (19%), Positives = 44/111 (40%), Gaps = 8/111 (7%)
Query 237 ITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLH 296
+ V S G+ G +++ +R+ +G + + V+ S + +G A+++G L
Sbjct 963 LRPPIVIHSSGKKYGFSLRAIRVY------MGDSDVYTVHHVVWS-VEEGSPAQEAG-LR 1014
Query 297 EGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV 347
GD + ING + G +V +LL ++ +
Sbjct 1015 AGDLITHINGESVLGLVHMDVVELLLKSGNKISLRTTALENTSIKVGPARK 1065
>sp|A6ZKU1|SLA1_YEAS7 Actin cytoskeleton-regulatory complex protein
SLA1 OS=Saccharomyces cerevisiae (strain YJM789) OX=307796
GN=SLA1 PE=3 SV=1
Length=1244
Score = 41.6 bits (96), Expect = 0.031, Method: Composition-based stats.
Identities = 15/67 (22%), Positives = 32/67 (48%), Gaps = 11/67 (16%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQED-PNWW--QAYREGDEDNQPLAGLV 407
+A + Y+P + +E D+L+++ + D +WW + G + +P+ GLV
Sbjct 9 RAVYAYEPQTPEELAIQE-------DDLLYLLQKSDIDDWWTVKKRVIGSDSEEPV-GLV 60
Query 408 PGKSFQQ 414
P ++
Sbjct 61 PSTYIEE 67
>sp|P43069|CDC25_CANAL Cell division control protein 25 OS=Candida
albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=CDC25
PE=1 SV=2
Length=1333
Score = 41.6 bits (96), Expect = 0.032, Method: Composition-based stats.
Identities = 14/64 (22%), Positives = 24/64 (38%), Gaps = 8/64 (13%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
V A +D+ + ++P GD +HV+S+ WW G+ G P
Sbjct 35 VIALYDFPGTQSSHLP-------LNLGDTIHVLSKSATGWWDGVVMGNSGELQ-RGWFPH 86
Query 410 KSFQ 413
+
Sbjct 87 NYVR 90
>sp|P32790|SLA1_YEAST Actin cytoskeleton-regulatory complex protein
SLA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 /
S288c) OX=559292 GN=SLA1 PE=1 SV=1
Length=1244
Score = 41.6 bits (96), Expect = 0.032, Method: Composition-based stats.
Identities = 15/67 (22%), Positives = 32/67 (48%), Gaps = 11/67 (16%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQED-PNWW--QAYREGDEDNQPLAGLV 407
+A + Y+P + +E D+L+++ + D +WW + G + +P+ GLV
Sbjct 9 RAVYAYEPQTPEELAIQE-------DDLLYLLQKSDIDDWWTVKKRVIGSDSEEPV-GLV 60
Query 408 PGKSFQQ 414
P ++
Sbjct 61 PSTYIEE 67
>sp|Q9Z762|DER_CHLPN GTPase Der OS=Chlamydia pneumoniae OX=83558
GN=der PE=3 SV=1
Length=487
Score = 41.2 bits (95), Expect = 0.032, Method: Composition-based stats.
Identities = 49/228 (21%), Positives = 74/228 (32%), Gaps = 44/228 (19%)
Query 456 DDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTT 515
+ + EE T E Q A + I LIG N G++ + L+N+E+ P TT
Sbjct 204 EGFSPEEPCTIPE---SPQQAPKTLKIALIGRPNVGKSSIINGLLNEER-CIIDNTPGTT 259
Query 516 RSRRD--QEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKIC 573
R D R Y F+ + IE S + I+ IC
Sbjct 260 RDNIDILYSHKDRQYLFIDTAGLRKMKSVKNSIEW---------ISSSRTEKAISRADIC 310
Query 574 LLSLR-TQS-------LKTLRNSDLKPYIIFIAPPSQERLRA-LLAK-----EGKN---- 615
LL + TQ + +L + KP+II I + L + +
Sbjct 311 LLVIDATQKLSSYEKRILSLISKRKKPHIILIN--KWDLLEEVRMEHYCKDLRATDPYLG 368
Query 616 ---------PKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQE 654
L++I E+ + T IVN L A
Sbjct 369 QAKMLCISATTKRNLKKIFSAIDELHHVVSNKVPTPIVNKTLASALHR 416
>sp|Q8TF65|GIPC2_HUMAN PDZ domain-containing protein GIPC2 OS=Homo
sapiens OX=9606 GN=GIPC2 PE=1 SV=1
Length=315
Score = 40.8 bits (94), Expect = 0.033, Method: Composition-based stats.
Identities = 20/65 (31%), Positives = 28/65 (43%), Gaps = 2/65 (3%)
Query 255 KIVRIEKARDIPLGATVRNEMDS-VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
K V + K+ D LG T+ + I RI GG + + GD + ING I G
Sbjct 116 KEVNVYKSED-SLGLTITDNGVGYAFIKRIKDGGVIDSVKTICVGDHIESINGENIVGWR 174
Query 314 VNEVF 318
+V
Sbjct 175 HYDVA 179
>sp|P37530|DGK_BACSU Deoxyguanosine kinase OS=Bacillus subtilis
(strain 168) OX=224308 GN=dgk PE=1 SV=1
Length=207
Score = 40.0 bits (92), Expect = 0.033, Method: Composition-based stats.
Identities = 33/216 (15%), Positives = 62/216 (29%), Gaps = 54/216 (25%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I + GP G+ L L +F + + F +I
Sbjct 7 IAIEGPIGAGKTTLATML----SQKFGFPMINEIVEDNPYL-----------DKFYDNIK 51
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLS-------------LRTQSLKTLRNS 588
F F + Y D+ + G+ + L L+ +
Sbjct 52 EWSFQLEMFFLCHRYKQLEDTSDHFLKKGQPVIADYHIYKNVIFAERTLSPHQLEKYKKI 111
Query 589 D-------LKP-YIIFIAPPSQERLRALLAKEGKNPKPEE---------------LREII 625
KP +II+I S L + K G+ + + ++++
Sbjct 112 YHLLTDDLPKPNFIIYIKA-SLPTLLHRIEKRGRPFEKKIETSYLEQLISDYEVAIKQLQ 170
Query 626 EKTREMEQN--NGHYFDTAIVNSDLDKAYQELLRLI 659
E E+ +G D + SD ++ + LI
Sbjct 171 EADPELTVLTVDGDSKDFVLNKSDFERIAAHVKELI 206
>sp|Q5PXS1|LCK_AOTNA Tyrosine-protein kinase Lck OS=Aotus nancymaae
OX=37293 GN=LCK PE=2 SV=4
Length=509
Score = 41.2 bits (95), Expect = 0.034, Method: Composition-based stats.
Identities = 44/273 (16%), Positives = 92/273 (34%), Gaps = 37/273 (14%)
Query 307 IEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPC 366
+ + GK LL + L+ + PP + V A Y PS D
Sbjct 28 VPLDGK-----ATLLFRNGSEVRDPLVRYEGSNPPASPLQDNLVIALHSYKPSHDGD--- 79
Query 367 RELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ-----------Q 415
L F+KG+ L ++ Q WW+A G +P + +
Sbjct 80 ----LGFEKGEQLRILEQN-GEWWKA----QSLTTGQEGFIPFNFVAKANSLEPEPWFFK 130
Query 416 REAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQP 475
+ K + P + + + + + ++ D + E++ + ++
Sbjct 131 NLSRKDAERQLLAPGNTHGSF-LIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNG 189
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA 535
P I G +EL + D + + ++++ Q+ D V R+
Sbjct 190 GFYISPRITF----PGLHELVRH-YTNASDGLCTRLSRPCQTQKPQKPWWEDEWEVPRET 244
Query 536 FE--ADIAAGKFIE-HGEFEKNLYGTSIDSVRQ 565
+ + AG+F E + + ++ S++Q
Sbjct 245 LKLVERLGAGQFGEVWMGYYNDHTKVAVKSLKQ 277
>sp|Q9V2C6|PGK2_PYRAB 2-phosphoglycerate kinase OS=Pyrococcus
abyssi (strain GE5 / Orsay) OX=272844 GN=pgk2 PE=3 SV=1
Length=302
Score = 40.4 bits (93), Expect = 0.034, Method: Composition-based stats.
Identities = 32/228 (14%), Positives = 60/228 (26%), Gaps = 69/228 (30%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHT--TRSRRDQEVAGRDYHFVSRQAF 536
I+L GP G++ + L F + T S R+ V
Sbjct 90 PLLILLGGPTGVGKSTIATELA------FRLGIRSVIGTDSIREVLRK------VITPEL 137
Query 537 EADIAAGKFIEHGEFEKNLYGTSI----------------DSVRQVINSGKICLLS---- 576
I F+ E + G+ I + + G ++
Sbjct 138 LPTIHTSTFLAWKEIKGTTSGSPIIAGFESQVSAVAVGVNAIIERAKREGLNAIIEGIHV 197
Query 577 ----LRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGK-------------NPKPE 619
+ + T I S+E L A + + + E
Sbjct 198 VPGFVDVKGEMTFMYM--------IVARSREDLEARFYERTRYSKRSANYYISHLDEIME 249
Query 620 ELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQ 667
R +IE+ R+ I N +L+K + ++ +
Sbjct 250 IQRYLIERARKFGVP-------VIENIELEKT---IRAIMEDIMERTI 287
>sp|Q99M51|NCK1_MOUSE SH2/SH3 adapter protein Nck1 OS=Mus musculus
OX=10090 GN=Nck1 PE=1 SV=1
Length=377
Score = 40.8 bits (94), Expect = 0.035, Method: Composition-based stats.
Identities = 19/65 (29%), Positives = 31/65 (48%), Gaps = 14/65 (22%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ--EDPNWWQAYREGDEDNQPLAGLV 407
V+A + + S+D L+F+KGD++ VI + DP WW+ + + GLV
Sbjct 195 VQALYPFSSSNDEE-------LNFEKGDVMDVIEKPENDPEWWKCRKING-----MVGLV 242
Query 408 PGKSF 412
P
Sbjct 243 PKNYV 247
>sp|E9EM69|SHO1_METRA High osmolarity signaling protein MOS1 OS=Metarhizium
robertsii (strain ARSEF 23 / ATCC MYA-3075) OX=655844
GN=MOS1 PE=2 SV=1
Length=306
Score = 40.4 bits (93), Expect = 0.035, Method: Composition-based stats.
Identities = 18/62 (29%), Positives = 24/62 (39%), Gaps = 10/62 (16%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
KA + Y+ + P +SF K +IL V WWQA R G G+ P
Sbjct 252 KAIYSYEAN-----PSDANEISFSKHEILDVSDVS-GRWWQARRRGTN----EIGIAPSN 301
Query 411 SF 412
Sbjct 302 YL 303
>sp|Q8DKI1|DER_THEVB GTPase Der OS=Thermosynechococcus vestitus
(strain NIES-2133 / IAM M-273 / BP-1) OX=197221 GN=der PE=3
SV=1
Length=449
Score = 40.8 bits (94), Expect = 0.035, Method: Composition-based stats.
Identities = 37/266 (14%), Positives = 79/266 (30%), Gaps = 41/266 (15%)
Query 416 REAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQP 475
A+ + ++ + W + ++ + + D ++TY
Sbjct 116 LVAVNKCESRQMGQVQAAEFWSLGLGEPYPISSIHGSGTGELLDQ--LITYLPAGETLPE 173
Query 476 ANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVA--GRDYHFVSR 533
A + + + G N G++ L L+ ++ S + TTR D + G Y F+
Sbjct 174 APEIQ-VAIAGRPNVGKSSLLNALIGSDR-AIVSPISGTTRDAIDTVIEHGGTQYRFIDT 231
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSV------------RQ-------VINSGKICL 574
E + V Q + + G+ C+
Sbjct 232 AGIRKRTHVAYGPEMFSVHRAFKAIHRSDVVLLVLDALEEITEQDQRLAGHIADQGRACV 291
Query 575 LSLR-TQSLKTLRNSDLKPYIIFIAPPSQERLRALLA-KEGKNP------KPEELREIIE 626
L + ++ + Y ++RL L E + + L +I
Sbjct 292 LIVNKWDAVLDKDTYTINAY--------RDRLYQRLHFLEWADALFVSAHTGQRLEKIFA 343
Query 627 KTREMEQNNGHYFDTAIVNSDLDKAY 652
+ + TA+VN + +A
Sbjct 344 AVDAAVEQHRRRVTTAVVNDVIQEAL 369
>sp|A4XSC0|DEGPL_PSEMY Probable periplasmic serine endoprotease
DegP-like OS=Pseudomonas mendocina (strain ymp) OX=399739
GN=Pmen_1471 PE=3 SV=1
Length=474
Score = 40.8 bits (94), Expect = 0.036, Method: Composition-based stats.
Identities = 14/68 (21%), Positives = 29/68 (43%), Gaps = 2/68 (3%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIE-IRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+++++++ G A+K G L GD +L +NG + D+ + L V+
Sbjct 293 GALVAQVLEDGPADK-GGLQVGDVILSLNGKPIVMSADLPHLVGGLKPGEKAEMDVVRDG 351
Query 336 QQIKPPPA 343
+ K
Sbjct 352 SRKKLKVT 359
>sp|P62484|ABI2_MOUSE Abl interactor 2 OS=Mus musculus OX=10090
GN=Abi2 PE=1 SV=1
Length=446
Score = 40.8 bits (94), Expect = 0.036, Method: Composition-based stats.
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 11/75 (15%)
Query 339 KPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDE 398
+ PP K YD + D +E LSFQ+G I++VI + D W++ G
Sbjct 376 EDPPWAPRAYLEKVVAIYDYTKD-----KEDELSFQEGAIIYVIKKNDDGWYEGVMNG-- 428
Query 399 DNQPLAGLVPGKSFQ 413
+ GL PG +
Sbjct 429 ----VTGLFPGNYVE 439
>sp|P74120|DER_SYNY3 GTPase Der OS=Synechocystis sp. (strain PCC
6803 / Kazusa) OX=1111708 GN=der PE=3 SV=1
Length=452
Score = 40.8 bits (94), Expect = 0.036, Method: Composition-based stats.
Identities = 39/279 (14%), Positives = 89/279 (32%), Gaps = 50/279 (18%)
Query 410 KSFQQQREAMKQTIEEDKEPEK----SGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILT 465
+ +QQ + + + + P++ + + W + + + D + L
Sbjct 106 QWLRQQSVPVILAVNKCESPDQGAIQAAEFWHLGLG---EPYPMSAIHGSGTGDLLDALL 162
Query 466 YEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQ--EV 523
+ +P + + ++G N G++ L L +++ S + TTR D E
Sbjct 163 EYLPAPQEEPEEDEIKVAIVGRPNVGKSSLLNALTGEQR-AIVSPISGTTRDAIDMVVER 221
Query 524 AGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSV------------RQ------ 565
G+ Y + E + V Q
Sbjct 222 NGQKYRLIDTAGIRRKKNVDYGAEFFGINRAFKAIRRADVVLFVLDVLDGVTEQDLKLAG 281
Query 566 -VINSGKICLLSLR-TQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEE--- 620
+I G+ +L + +++ Y I+ +E+L A L +
Sbjct 282 RIIEDGRAVVLVINKWDAVEK------DSYTIY---EHREQLMARLYF--MDWAEMIFVS 330
Query 621 ------LREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQ 653
+++I++ Q + TA++N L++A
Sbjct 331 AQTGLRVQKILDCVDIAAQEHRRRVTTAVINEVLEEAVS 369
>sp|E3RIP0|SHO1_PYRTT High osmolarity signaling protein sho1 OS=Pyrenophora
teres f. teres (strain 0-1) OX=861557 GN=sho1
PE=3 SV=1
Length=309
Score = 40.4 bits (93), Expect = 0.038, Method: Composition-based stats.
Identities = 21/80 (26%), Positives = 29/80 (36%), Gaps = 16/80 (20%)
Query 333 IPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 392
P + P + KA + Y+ + D +SFQK DIL V WWQA
Sbjct 243 QPQEISIEYPYRA-----KAIYSYEANPDDA-----NEISFQKHDILEVSDVS-GRWWQA 291
Query 393 YREGDEDNQPLAGLVPGKSF 412
+ E G+ P
Sbjct 292 KKPNGE-----TGIAPSNYL 306
>sp|Q92JA1|DEGPL_RICCN Probable periplasmic serine endoprotease
DegP-like OS=Rickettsia conorii (strain ATCC VR-613 / Malish
7) OX=272944 GN=htrA PE=3 SV=2
Length=508
Score = 40.8 bits (94), Expect = 0.039, Method: Composition-based stats.
Identities = 14/84 (17%), Positives = 34/84 (40%), Gaps = 4/84 (5%)
Query 264 DIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSD 323
LG V+++++ + G +K+G + GD ++E I ++ V +
Sbjct 309 SEGLGL---KNTRGVLVAKVQEDGPGDKAG-IKTGDIIIEFADIPVKNTKKLRVIIADAP 364
Query 324 MHGTLTFVLIPSQQIKPPPAKETV 347
+ + ++ ++ P K T
Sbjct 365 IDQEVKVKILRDKKELELPIKITS 388
>sp|Q01621|LCK_RAT Proto-oncogene tyrosine-protein kinase LCK
OS=Rattus norvegicus OX=10116 GN=Lck PE=1 SV=3
Length=509
Score = 40.8 bits (94), Expect = 0.039, Method: Composition-based stats.
Identities = 41/245 (17%), Positives = 84/245 (34%), Gaps = 36/245 (15%)
Query 340 PPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDED 399
PP + V A Y+PS D L F+KG+ L ++ Q WW+A
Sbjct 56 PPASPLQDNLVIALHSYEPSHDGD-------LGFEKGEQLRILEQS-GEWWKA----QSL 103
Query 400 NQPLAGLVPGKSFQQ-----------QREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKV 448
G +P + + + K + P + + + +
Sbjct 104 TTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSF-LIRESESTAGS 162
Query 449 LYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFA 508
+ ++ D + E++ + ++ P I G ++L + D
Sbjct 163 FSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITF----PGLHDLVRH-YTNASDGLC 217
Query 509 SAVPHTTRSRRDQEVAGRDYHFVSRQAFE--ADIAAGKFIEHGEFEKNLY-GTSIDSVRQ 565
+ + ++++ Q+ D V R+ + + AG+F GE Y G + +V+
Sbjct 218 TKLSRPCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQF---GEVWMGYYNGHTKVAVKS 274
Query 566 VINSG 570
+ G
Sbjct 275 -LKQG 278
>sp|P06240|LCK_MOUSE Proto-oncogene tyrosine-protein kinase LCK
OS=Mus musculus OX=10090 GN=Lck PE=1 SV=4
Length=509
Score = 40.8 bits (94), Expect = 0.039, Method: Composition-based stats.
Identities = 41/245 (17%), Positives = 84/245 (34%), Gaps = 36/245 (15%)
Query 340 PPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDED 399
PP + V A Y+PS D L F+KG+ L ++ Q WW+A
Sbjct 56 PPASPLQDNLVIALHSYEPSHDGD-------LGFEKGEQLRILEQS-GEWWKA----QSL 103
Query 400 NQPLAGLVPGKSFQQ-----------QREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKV 448
G +P + + + K + P + + + +
Sbjct 104 TTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSF-LIRESESTAGS 162
Query 449 LYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFA 508
+ ++ D + E++ + ++ P I G ++L + D
Sbjct 163 FSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITF----PGLHDLVRH-YTNASDGLC 217
Query 509 SAVPHTTRSRRDQEVAGRDYHFVSRQAFE--ADIAAGKFIEHGEFEKNLY-GTSIDSVRQ 565
+ + ++++ Q+ D V R+ + + AG+F GE Y G + +V+
Sbjct 218 TKLSRPCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQF---GEVWMGYYNGHTKVAVKS 274
Query 566 VINSG 570
+ G
Sbjct 275 -LKQG 278
>sp|Q5DU57|SPT13_MOUSE Spermatogenesis-associated protein 13 OS=Mus
musculus OX=10090 GN=Spata13 PE=1 SV=2
Length=656
Score = 40.8 bits (94), Expect = 0.039, Method: Composition-based stats.
Identities = 30/171 (18%), Positives = 60/171 (35%), Gaps = 29/171 (17%)
Query 235 EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGL 294
P+ +V + ++ ++ P+G + S + G AE S L
Sbjct 57 PPVPAHQVPPYKAV----SARLRPFTFSQSTPIGLDRVGRRRQMKTSNVSSDGGAESSAL 112
Query 295 LHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ---IKPPPAKETVIHVK 351
++ G + + ++ L + L P + I + +V+ +
Sbjct 113 ------------VDDNGSEEDFSYEELCQANPRY---LQPGGEQLAINELISDGSVVCAE 157
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQP 402
A +D+ DD L F+ GD++ V+ + +WW E E P
Sbjct 158 ALWDHVTMDD-------QELGFKAGDVIQVLEASNKDWWWGRNEDKEAWFP 201
>sp|B2VV00|SHO1_PYRTR High osmolarity signaling protein sho1 OS=Pyrenophora
tritici-repentis (strain Pt-1C-BFP) OX=426418
GN=sho1 PE=3 SV=1
Length=295
Score = 40.4 bits (93), Expect = 0.040, Method: Composition-based stats.
Identities = 19/62 (31%), Positives = 25/62 (40%), Gaps = 11/62 (18%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
KA + Y+ + D +SFQK DIL V WWQA + E G+ P
Sbjct 242 KAIYSYEANPDDA-----NEISFQKHDILEVSDVS-GRWWQAKKPNGE-----TGIAPSN 290
Query 411 SF 412
Sbjct 291 YL 292
>sp|Q9UPX8|SHAN2_HUMAN SH3 and multiple ankyrin repeat domains
protein 2 OS=Homo sapiens OX=9606 GN=SHANK2 PE=1 SV=4
Length=1849
Score = 41.2 bits (95), Expect = 0.040, Method: Composition-based stats.
Identities = 19/119 (16%), Positives = 41/119 (34%), Gaps = 18/119 (15%)
Query 238 TDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSV---------------IISR 282
+ + S E K V ++K + G +R +
Sbjct 610 SYDSFDTSSDCIIEE--KTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLES 667
Query 283 IVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
+ +GG A ++G L GD ++E+N + +V +++ L ++ + P
Sbjct 668 VDEGGVAWQAG-LRTGDFLIEVNNENVVKVGHRQVVNMIRQGGNHLVLKVVTVTRNLDP 725
>sp|Q8IVH4|MMAA_HUMAN Methylmalonic aciduria type A protein, mitochondrial
OS=Homo sapiens OX=9606 GN=MMAA PE=1 SV=1
Length=418
Score = 40.8 bits (94), Expect = 0.040, Method: Composition-based stats.
Identities = 19/153 (12%), Positives = 53/153 (35%), Gaps = 23/153 (15%)
Query 464 LTYEEMSLYHQP---ANRKRPII----LIGPQNCGQNELRQ---RLMNKEKDRFASAVPH 513
+ +++ LYH+ +N+ +P+ L GP G++ + +++ + + +
Sbjct 121 VLLQKVLLYHREQEQSNKGKPLAFRVGLSGPPGAGKSTFIEYFGKMLTERGHKLSVLAVD 180
Query 514 TTRSRRDQEVAGRDYHFVSRQAFEAD-IAAGKFIEHGEFEKNLYGTSIDSVRQVI---NS 569
+ + G + +I L G + + ++ +
Sbjct 181 PSSCTSGGSLLG------DKTRMTELSRDMNAYIRPSPTRGTLGGVTRTTNEAILLCEGA 234
Query 570 GKICLLSLRTQSLKT--LRNSDLKPYIIFIAPP 600
G +L + T + +D+ + + PP
Sbjct 235 GYDIIL-IETVGVGQSEFAVADMVDMFVLLLPP 266
>sp|B2ANF9|SHO1_PODAN High osmolarity signaling protein SHO1 OS=Podospora
anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC
10383) OX=515849 GN=SHO1 PE=3 SV=1
Length=317
Score = 40.4 bits (93), Expect = 0.040, Method: Composition-based stats.
Identities = 26/109 (24%), Positives = 39/109 (36%), Gaps = 11/109 (10%)
Query 304 INGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPY 363
+ G++ G + V G + L S P E KA + Y+ +
Sbjct 217 VGGMQSSGMRNSAVPPPFQSTLGQKSNGLPGSSDGDIAPPTEYPYRAKAIYSYEAN---- 272
Query 364 VPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSF 412
P +SFQK +IL V WWQA +E + G+ P
Sbjct 273 -PEDANEISFQKHEILEVSDVS-GRWWQARKENGD-----TGIAPSNYL 314
>sp|P0CR78|HSE1_CRYNJ Class E vacuolar protein-sorting machinery
protein HSE1 OS=Cryptococcus neoformans var. neoformans serotype
D (strain JEC21 / ATCC MYA-565) OX=214684 GN=HSE1 PE=3
SV=1
Length=660
Score = 40.8 bits (94), Expect = 0.040, Method: Composition-based stats.
Identities = 18/100 (18%), Positives = 36/100 (36%), Gaps = 13/100 (13%)
Query 333 IPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 392
P + P T V+A + + + L F++GD++ V+ + WW+
Sbjct 245 QPLEPEPPRVDLNTATRVRAIYPFTGQEVGE-------LDFERGDVIKVLDRGFKEWWRG 297
Query 393 YREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKS 432
G G+ P + E + ++E + E
Sbjct 298 ACNGK------IGIFPVTYVEALPEPTPKELQEKAQEEAR 331
>sp|Q8AXV0|SH3G1_CHICK Endophilin-A2 OS=Gallus gallus OX=9031
GN=SH3GL1 PE=1 SV=1
Length=367
Score = 40.4 bits (93), Expect = 0.043, Method: Composition-based stats.
Identities = 17/56 (30%), Positives = 29/56 (52%), Gaps = 7/56 (13%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGL 406
KA +D++P +D L F++GDI+ + +Q D NW++ G PL +
Sbjct 311 KALYDFEPENDGE-------LGFKEGDIITLTNQIDENWYEGMINGQSGFFPLNYV 359
>sp|O23614|CTPA2_ARATH Carboxyl-terminal-processing peptidase
2, chloroplastic OS=Arabidopsis thaliana OX=3702 GN=CTPA2 PE=1
SV=1
Length=515
Score = 40.8 bits (94), Expect = 0.044, Method: Composition-based stats.
Identities = 12/90 (13%), Positives = 29/90 (32%), Gaps = 2/90 (2%)
Query 262 ARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL 321
I +++ GG A ++G+L GD + I+ + + +L
Sbjct 213 GLSIGYPTASDGPPAGLVVISAAPGGPANRAGIL-PGDVIQGIDNTTTETLTIYDAAQML 271
Query 322 SDMHGT-LTFVLIPSQQIKPPPAKETVIHV 350
G+ + + + + + V
Sbjct 272 QGPEGSAVELAIRSGPETRLLTLTRERVSV 301
>sp|Q74KZ7|KTHY_LACJO Thymidylate kinase OS=Lactobacillus johnsonii
(strain CNCM I-12250 / La1 / NCC 533) OX=257314 GN=tmk
PE=3 SV=1
Length=213
Score = 39.7 bits (91), Expect = 0.044, Method: Composition-based stats.
Identities = 13/111 (12%), Positives = 33/111 (30%), Gaps = 10/111 (9%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R I GP G+ + ++ + T + + + E
Sbjct 2 RGYLITFEGPDGAGKTTVINEIIKQLPQSLQERTLVTREPGGSKISENIRTIILDPENKE 61
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLS--LR----TQSL 582
D + + +++ + +R + +GK+ L + Q +
Sbjct 62 MDDRTEALLYAAQRSQHV----SEVIRPALATGKVVLSDRFIDSSLAYQGV 108
>sp|P26050|NODI_BRADU Nod factor export ATP-binding protein I
OS=Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528
/ IAM 13628 / NBRC 14792 / USDA 110) OX=224911 GN=nodI PE=3
SV=2
Length=306
Score = 40.4 bits (93), Expect = 0.044, Method: Composition-based stats.
Identities = 18/93 (19%), Positives = 32/93 (34%), Gaps = 10/93 (11%)
Query 478 RKRPIILIGPQNCGQNELRQRLMN-KEKDRFASAV---PHTTRSRRDQEVAGRDYHFVSR 533
R L+GP G++ + + L+ DR V P +R+R + G
Sbjct 32 RGECFGLLGPNGAGKSTIARMLLGMISPDRGKITVLDEPVPSRARAARVRVGV------V 85
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQV 566
F+ E+ +G S ++ V
Sbjct 86 PQFDNLEPEFTVRENLLVFGRYFGMSARTIEAV 118
>sp|Q7V7P0|PSTB_PROMM Phosphate import ATP-binding protein PstB
OS=Prochlorococcus marinus (strain MIT 9313) OX=74547 GN=pstB
PE=3 SV=1
Length=272
Score = 40.0 bits (92), Expect = 0.045, Method: Composition-based stats.
Identities = 14/58 (24%), Positives = 24/58 (41%), Gaps = 2/58 (3%)
Query 466 YEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV 523
+E + + R + LIGP CG++ + + L N+ D T R D +
Sbjct 30 FEAVRHVYCEIPRGKITALIGPSGCGKSTILRSL-NRMNDLIEGC-SLTGRVMFDGDD 85
>sp|A8AAI6|KCY_IGNH4 Cytidylate kinase OS=Ignicoccus hospitalis
(strain KIN4/I / DSM 18386 / JCM 14125) OX=453591 GN=cmk PE=3
SV=1
Length=172
Score = 39.3 bits (90), Expect = 0.045, Method: Composition-based stats.
Identities = 8/35 (23%), Positives = 19/35 (54%), Gaps = 0/35 (0%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTR 516
+++ GP G++ + ++L ++ RF SA +
Sbjct 4 VVISGPPGSGKSTVAKKLASELGLRFVSAGSVFRK 38
>sp|Q9UUH3|MUG58_SCHPO Uncharacterized kinase mug58 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=mug58
PE=1 SV=1
Length=277
Score = 40.0 bits (92), Expect = 0.046, Method: Composition-based stats.
Identities = 19/107 (18%), Positives = 31/107 (29%), Gaps = 16/107 (15%)
Query 471 LYHQPANRKRPII--LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDY 528
L QP RP I + GPQ G++ L L + TR D
Sbjct 15 LEKQPKPEGRPFILGISGPQGSGKSTLASALDTE-----------LTRKNESVVKFSLDD 63
Query 529 HFVSRQAFEADIA---AGKFIEHGEFEKNLYGTSIDSVRQVINSGKI 572
+++ ++H T +++V G
Sbjct 64 FYLTHAEQVELAKNNPNNPLVQHRGLAGTHDVTFLNNVLNAFVKGSD 110
>sp|Q3T005|PDLI4_BOVIN PDZ and LIM domain protein 4 OS=Bos taurus
OX=9913 GN=PDLIM4 PE=2 SV=1
Length=331
Score = 40.4 bits (93), Expect = 0.046, Method: Composition-based stats.
Identities = 21/117 (18%), Positives = 35/117 (30%), Gaps = 4/117 (3%)
Query 257 VRIEKARDIPLGATVRNEMD-SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVN 315
V + + + ISR+ G A L GD + ING
Sbjct 5 VTLRGPSPWGFRLVGGRDFSVPLTISRVHAGSKAAL-AALCPGDLIQAINGESTELMTHL 63
Query 316 EVFDLLSDMHGTLTFVL-IPSQQIKPPPAKETVIHV-KAHFDYDPSDDPYVPCRELG 370
E + + LT + P + P ++ + H D + D + R
Sbjct 64 EAQNRIKGCRDHLTLSVSRPEGRSWPSTPEDNKAQAHRIHIDSEAQDGSPLTSRRPS 120
>sp|Q8IUC4|RHPN2_HUMAN Rhophilin-2 OS=Homo sapiens OX=9606 GN=RHPN2
PE=1 SV=1
Length=686
Score = 40.8 bits (94), Expect = 0.047, Method: Composition-based stats.
Identities = 40/223 (18%), Positives = 81/223 (36%), Gaps = 24/223 (11%)
Query 125 EDLFSSLK-HIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMN--KASPPFP 181
E S L H+ L + ++ + + + A H + K
Sbjct 379 EKCLSQLYDHMPEGLTPLATLKN-DQQRRQLGKSHLRRAMAHHEESVREASLCKKLRSIE 437
Query 182 LISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDER 241
++ AQE ++ L H+E +L L++ P + A E ++ L +
Sbjct 438 VLQKVLCAAQE-RSRLTYAQHQEEDDLLNLIDAPSVVA-----KTEQEVDIILPQFSKLT 491
Query 242 VYESIGQYGGETV----------KIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEK 291
V + + G +V + +R A + LG T+R V + + +A
Sbjct 492 VTDFFQKLGPLSVFSANKRWTPPRSIRFT-AEEGDLGFTLRGN-APVQVHFLDPYCSASV 549
Query 292 SGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG-TLTFVLI 333
+G EGD ++ I ++ + ++EV LL + ++
Sbjct 550 AGA-REGDYIVSIQLVDCKWLTLSEVMKLLKSFGEDEIEMKVV 591
>sp|B6QEE0|SHO1_TALMQ High osmolarity signaling protein sho1 OS=Talaromyces
marneffei (strain ATCC 18224 / CBS 334.59 / QM
7333) OX=441960 GN=sho1 PE=3 SV=1
Length=282
Score = 40.0 bits (92), Expect = 0.049, Method: Composition-based stats.
Identities = 18/62 (29%), Positives = 23/62 (37%), Gaps = 11/62 (18%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
KA + YD + D +SF KG+ L V WWQA R G+ P
Sbjct 229 KAIYSYDANPDDA-----NEISFAKGEELEVSDVS-GRWWQARR-----ANGETGIAPSN 277
Query 411 SF 412
Sbjct 278 YL 279
>sp|Q8CBW3|ABI1_MOUSE Abl interactor 1 OS=Mus musculus OX=10090
GN=Abi1 PE=1 SV=3
Length=481
Score = 40.4 bits (93), Expect = 0.049, Method: Composition-based stats.
Identities = 18/64 (28%), Positives = 28/64 (44%), Gaps = 13/64 (20%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
V A +DY D LSF++G I++VI + D W++ + GL PG
Sbjct 424 VVAIYDYTKDKDDE-------LSFKEGAIIYVIKKNDDGWFEGVC------NRVTGLFPG 470
Query 410 KSFQ 413
+
Sbjct 471 NYVE 474
>sp|B3LVG7|HTRA2_DROAN Serine protease HTRA2, mitochondrial OS=Drosophila
ananassae OX=7217 GN=HtrA2 PE=3 SV=1
Length=426
Score = 40.4 bits (93), Expect = 0.049, Method: Composition-based stats.
Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 3/64 (5%)
Query 272 RNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV 331
N V++ +++ G A SG L GD V IN EI+ +V+D L+D L V
Sbjct 353 SNLTHGVLVWKVIVGSPAH-SGGLQPGDIVTHINKKEIKNSS--DVYDALADNSKHLDIV 409
Query 332 LIPS 335
++
Sbjct 410 ILRG 413
>sp|D6PVB4|SHO1A_HORWE High osmolarity signaling protein SHO1A
OS=Hortaea werneckii OX=91943 GN=SHO1A PE=3 SV=1
Length=321
Score = 40.0 bits (92), Expect = 0.049, Method: Composition-based stats.
Identities = 21/77 (27%), Positives = 29/77 (38%), Gaps = 16/77 (21%)
Query 336 QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYRE 395
QQ P + KA + Y+ + D +SF K +IL V WWQA +E
Sbjct 258 QQPTEYPYRA-----KAIYSYEANPDDA-----NEISFNKHEILEVSDVS-GRWWQAKKE 306
Query 396 GDEDNQPLAGLVPGKSF 412
E G+ P
Sbjct 307 NGE-----TGIAPSNYL 318
>sp|Q9DC29|ABCB6_MOUSE ATP-binding cassette sub-family B member
6 OS=Mus musculus OX=10090 GN=Abcb6 PE=1 SV=1
Length=842
Score = 40.8 bits (94), Expect = 0.049, Method: Composition-based stats.
Identities = 14/89 (16%), Positives = 32/89 (36%), Gaps = 11/89 (12%)
Query 413 QQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLY 472
+ + + E K+ +G L K + A+ + T +++S
Sbjct 561 MENMFDLLKEETEVKDVPGAGPLRFHKGRIEFENVHFSYADGQE--------TLQDVSFT 612
Query 473 HQPANRKRPIILIGPQNCGQNELRQRLMN 501
P + + L+GP G++ + + L
Sbjct 613 VMP---GQTVALVGPSGAGKSTILRLLFR 638
>sp|Q9NP58|ABCB6_HUMAN ATP-binding cassette sub-family B member
6 OS=Homo sapiens OX=9606 GN=ABCB6 PE=1 SV=1
Length=842
Score = 40.8 bits (94), Expect = 0.049, Method: Composition-based stats.
Identities = 20/128 (16%), Positives = 44/128 (34%), Gaps = 22/128 (17%)
Query 413 QQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLY 472
+ + + E K+ +G L K + A+ + T +++S
Sbjct 561 MENMFDLLKEETEVKDLPGAGPLRFQKGRIEFENVHFSYADGRE--------TLQDVSFT 612
Query 473 HQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVS 532
P + + L+GP G++ + + L F R + G+D V+
Sbjct 613 VMP---GQTLALVGPSGAGKSTILRLLFR-----FYDISSGCIR------IDGQDISQVT 658
Query 533 RQAFEADI 540
+ + + I
Sbjct 659 QASLRSHI 666
>sp|Q2H3I7|SHO1_CHAGB High osmolarity signaling protein SHO1 OS=Chaetomium
globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962
/ NBRC 6347 / NRRL 1970) OX=306901 GN=SHO1 PE=3 SV=1
Length=297
Score = 40.0 bits (92), Expect = 0.049, Method: Composition-based stats.
Identities = 21/79 (27%), Positives = 30/79 (38%), Gaps = 13/79 (16%)
Query 334 PSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAY 393
P+ +I PP E KA + Y+ + P +SF K +IL V WWQA
Sbjct 229 PNAEIVPPT--EYPYRAKAIYSYEAN-----PEDANEISFSKHEILEVSDVS-GRWWQAR 280
Query 394 REGDEDNQPLAGLVPGKSF 412
+ G+ P
Sbjct 281 K-----ESGETGIAPSNYL 294
>sp|Q9QZM5|ABI1_RAT Abl interactor 1 OS=Rattus norvegicus OX=10116
GN=Abi1 PE=1 SV=3
Length=476
Score = 40.4 bits (93), Expect = 0.050, Method: Composition-based stats.
Identities = 18/64 (28%), Positives = 28/64 (44%), Gaps = 13/64 (20%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
V A +DY D LSF++G I++VI + D W++ + GL PG
Sbjct 419 VVAIYDYTKDKDDE-------LSFKEGAIIYVIKKNDDGWFEGVC------NRVTGLFPG 465
Query 410 KSFQ 413
+
Sbjct 466 NYVE 469
>sp|Q9R9I1|HTRB_BACSU Serine protease Do-like HtrB OS=Bacillus
subtilis (strain 168) OX=224308 GN=htrB PE=2 SV=1
Length=458
Score = 40.4 bits (93), Expect = 0.050, Method: Composition-based stats.
Identities = 18/112 (16%), Positives = 45/112 (40%), Gaps = 6/112 (5%)
Query 233 QLEPITDERVYESIGQYGGETVKIVRIEKA----RDIPLGATVRNEMDSVIISRIVKGGA 288
+EPI D+ + V+++ + + ++ LG V + +
Sbjct 333 DVEPIVDQLLQNGKVDRPFLGVQMIDMSQVPETYQENTLGLFGDQLGKGVYVKEVQANSP 392
Query 289 AEKSGLLHEGDEVLEINGIEIR-GKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
AEK+G + D ++++NG ++ D+ ++ + T ++ + K
Sbjct 393 AEKAG-IKSEDVIVKLNGKDVESSADIRQILYKDLKVGDKTTIQVLRKGKTK 443
>sp|Q8BWR8|RHPN2_MOUSE Rhophilin-2 OS=Mus musculus OX=10090 GN=Rhpn2
PE=1 SV=2
Length=686
Score = 40.8 bits (94), Expect = 0.051, Method: Composition-based stats.
Identities = 35/188 (19%), Positives = 66/188 (35%), Gaps = 10/188 (5%)
Query 153 LVQNKDFQNAFKIHNAITVHMN--KASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTA 210
L+ A H N K ++ + A + +T LK H+E +L
Sbjct 407 LLGKGHLHRAIGFHEESLREANLCKKLRDIQVLRDVLSAAHQ-RTQLKHTQHREDDDLLN 465
Query 211 LLNTPHIQALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVK----IVRIEKARDIP 266
L++ P + K+ + +TD + + +
Sbjct 466 LIDAPDVLPKTEREVKITFPDFSKVTVTDFFQKLGPLSVFSASKRWSPPRGIHFTVEEGD 525
Query 267 LGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG 326
LG T+R V + + +A +G EGD ++ I G++ + V+EV LL G
Sbjct 526 LGFTLRGNT-PVQVHFLDPHCSASLAGA-KEGDYIVSIQGVDCKWLTVSEVMKLLKSFGG 583
Query 327 -TLTFVLI 333
+ ++
Sbjct 584 EEVEMKVV 591
>sp|P36202|PDLI4_RAT PDZ and LIM domain protein 4 OS=Rattus norvegicus
OX=10116 GN=Pdlim4 PE=1 SV=2
Length=330
Score = 40.0 bits (92), Expect = 0.052, Method: Composition-based stats.
Identities = 22/111 (20%), Positives = 33/111 (30%), Gaps = 5/111 (5%)
Query 257 VRIEKARDIPLGATVRNEMD-SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVN 315
V + + + ISR+ G A L GD + ING
Sbjct 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAAL-AALCPGDSIQAINGESTELMTHL 63
Query 316 EVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAH-FDYDPSDDPYVP 365
E + + H LT + + P + +AH DP P
Sbjct 64 EAQNRIKGCHDHLTLSVSRPENKNWPSSPNDK--AQAHRIHIDPEAQDGSP 112
>sp|O60307|MAST3_HUMAN Microtubule-associated serine/threonine-protein
kinase 3 OS=Homo sapiens OX=9606 GN=MAST3 PE=1 SV=2
Length=1309
Score = 40.8 bits (94), Expect = 0.052, Method: Composition-based stats.
Identities = 21/111 (19%), Positives = 43/111 (39%), Gaps = 8/111 (7%)
Query 237 ITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLH 296
+ V S G+ G +++ +R+ +G + + V+ S + G A+++G L
Sbjct 947 LRPPIVIHSSGKKYGFSLRAIRVY------MGDSDVYTVHHVVWS-VEDGSPAQEAG-LR 998
Query 297 EGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV 347
GD + ING + G +V +LL ++ +
Sbjct 999 AGDLITHINGESVLGLVHMDVVELLLKSGNKISLRTTALENTSIKVGPARK 1049
>sp|A2AKB4|FRPD1_MOUSE FERM and PDZ domain-containing protein
1 OS=Mus musculus OX=10090 GN=Frmpd1 PE=1 SV=1
Length=1549
Score = 40.8 bits (94), Expect = 0.052, Method: Composition-based stats.
Identities = 14/71 (20%), Positives = 29/71 (41%), Gaps = 2/71 (3%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+E + + + GG+A G L GD++L++N D+L + L+ +
Sbjct 74 SETLPLTVVAVTAGGSAH--GKLFPGDQILQMNNELAEDLSCERAADILRETEDALSITV 131
Query 333 IPSQQIKPPPA 343
+ P +
Sbjct 132 VRCTSGVPKSS 142
>sp|P10686|PLCG1_RAT 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase
gamma-1 OS=Rattus norvegicus OX=10116 GN=Plcg1
PE=1 SV=1
Length=1290
Score = 40.8 bits (94), Expect = 0.052, Method: Composition-based stats.
Identities = 20/81 (25%), Positives = 30/81 (37%), Gaps = 12/81 (15%)
Query 334 PSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAY 393
P ++ P VKA FDY RE L+F K I+ + ++D WW
Sbjct 780 PGFYVEANPMPTFKCAVKALFDYKAQ-------REDELTFTKSAIIQNVEKQDGGWW--- 829
Query 394 REGDEDNQPLAGLVPGKSFQQ 414
GD + P ++
Sbjct 830 -RGDYGGKKQL-WFPSNYVEE 848
>sp|Q9FT77|RLM3_ARATH Disease resistance protein RLM3 OS=Arabidopsis
thaliana OX=3702 GN=RLM3 PE=2 SV=1
Length=796
Score = 40.8 bits (94), Expect = 0.052, Method: Composition-based stats.
Identities = 32/237 (14%), Positives = 73/237 (31%), Gaps = 43/237 (18%)
Query 414 QQREAMKQTIEEDKEPEKSGKLWCAK------KNKKKRKKVLYNANKNDDYDNEEILTYE 467
++R+ M+ E + + W ++ K K+ +N D+ E
Sbjct 131 EKRKWMRALAEVAHLAGEDLRNWRSEAEMLENIAKDVSNKLFPPSNNFSDFVGIEAHIEA 190
Query 468 EMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRD 527
+S+ + + R I + GP G+ + + L ++ K F + + + +
Sbjct 191 LISMLRFDSKKARMIGICGPSETGKTTIGRALYSRLKSDFHHRAFVAYKRKIRSDYDQKL 250
Query 528 YH---FVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKT 584
Y F+S + DI + +V Q + K+ ++ ++
Sbjct 251 YWEEQFLSEILCQKDIKIEEC---------------GAVEQRLKHTKVLIVLDDVDDIEL 295
Query 585 LRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEEL--REIIEKTREMEQNNGHYF 639
L+ L + G K + + + K + F
Sbjct 296 LKT-----------------LVGRIRWFGSESKIVVITQKRELLKAHNIAHVYEVGF 335
>sp|Q62077|PLCG1_MOUSE 1-phosphatidylinositol 4,5-bisphosphate
phosphodiesterase gamma-1 OS=Mus musculus OX=10090 GN=Plcg1
PE=1 SV=2
Length=1302
Score = 40.8 bits (94), Expect = 0.054, Method: Composition-based stats.
Identities = 20/81 (25%), Positives = 30/81 (37%), Gaps = 12/81 (15%)
Query 334 PSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAY 393
P ++ P VKA FDY RE L+F K I+ + ++D WW
Sbjct 780 PGFYVEANPMPTFKCAVKALFDYKAQ-------REDELTFTKSAIIQNVEKQDGGWW--- 829
Query 394 REGDEDNQPLAGLVPGKSFQQ 414
GD + P ++
Sbjct 830 -RGDYGGKKQL-WFPSNYVEE 848
>sp|Q39E73|MSBA_BURL3 ATP-dependent lipid A-core flippase OS=Burkholderia
lata (strain ATCC 17760 / DSM 23089 / LMG 22485
/ NCIMB 9086 / R18194 / 383) OX=482957 GN=msbA PE=3 SV=2
Length=593
Score = 40.4 bits (93), Expect = 0.054, Method: Composition-based stats.
Identities = 27/173 (16%), Positives = 53/173 (31%), Gaps = 28/173 (16%)
Query 408 PGKSFQQQREAMKQTIEEDKEP----EKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEI 463
P K + +++ + + ++ + + + + + N DY E
Sbjct 307 PLKHLIDVNQPLQRGMTAAELIFGLIDEPAEPQGGGRPLAQSRGDIEFRNVTFDYGAAER 366
Query 464 LTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQE- 522
T + +S P I L GP G+ L L D
Sbjct 367 PTLDRISFKVAP---GEMIALAGPSGSGKTTLVNLLPRFFD-------------PTDGAI 410
Query 523 -VAGR---DYHFVSRQAFEADIAAGKFIEHGEFEKNL-YG-TS-IDSVRQVIN 568
V G DY + ++ A ++ + + N+ YG T V+ +
Sbjct 411 LVDGVPVADYDLHALRSQMAMVSQDVVLFNDTIAANVAYGQTPDRARVQAALE 463
>sp|F1MDL2|INTU_BOVIN Protein inturned OS=Bos taurus OX=9913 GN=INTU
PE=3 SV=2
Length=933
Score = 40.4 bits (93), Expect = 0.055, Method: Composition-based stats.
Identities = 12/75 (16%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ +++ ++ GG+A KSG + GD ++ +N +E+ +++ V + +
Sbjct 204 GGGERLVVHGLLPGGSAMKSGQVLIGDVLVAVNDVEVTSENIERVLSCIPGPMQ-VKLTF 262
Query 333 IPSQQIKPPPAKETV 347
+ +K +
Sbjct 263 ENAYAMKKETTQPRQ 277
>sp|Q2KJA1|SH3G1_BOVIN Endophilin-A2 OS=Bos taurus OX=9913 GN=SH3GL1
PE=2 SV=1
Length=368
Score = 40.0 bits (92), Expect = 0.056, Method: Composition-based stats.
Identities = 20/90 (22%), Positives = 35/90 (39%), Gaps = 13/90 (14%)
Query 323 DMHGTLTFVLIPSQQIKPPPAKETVI------HVKAHFDYDPSDDPYVPCRELGLSFQKG 376
+T KP + KA +D++P +D L F +G
Sbjct 278 AAAPKITASSSFRSSDKPVRTPSRSMPPLDQPSCKALYDFEPENDGE-------LGFHEG 330
Query 377 DILHVISQEDPNWWQAYREGDEDNQPLAGL 406
DI+ + +Q D NW++ +G PL+ +
Sbjct 331 DIITLTNQIDENWYEGMLDGQSGFFPLSYV 360
>sp|O70595|ABCB6_RAT ATP-binding cassette sub-family B member
6 OS=Rattus norvegicus OX=10116 GN=Abcb6 PE=1 SV=1
Length=836
Score = 40.4 bits (93), Expect = 0.057, Method: Composition-based stats.
Identities = 14/89 (16%), Positives = 32/89 (36%), Gaps = 11/89 (12%)
Query 413 QQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLY 472
+ + + E K+ +G L K + A+ + T +++S
Sbjct 561 MENMFDLLKEETEVKDVPGAGPLRFHKGRVEFENVHFSYADGRE--------TLQDVSFT 612
Query 473 HQPANRKRPIILIGPQNCGQNELRQRLMN 501
P + + L+GP G++ + + L
Sbjct 613 VMP---GQTVALVGPSGAGKSTILRLLFR 638
>sp|C3MVX8|KCY_SULIM Cytidylate kinase OS=Sulfolobus islandicus
(strain M.14.25 / Kamchatka #1) OX=427317 GN=cmk PE=3 SV=1
Length=189
Score = 38.9 bits (89), Expect = 0.057, Method: Composition-based stats.
Identities = 29/201 (14%), Positives = 67/201 (33%), Gaps = 37/201 (18%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF--EA 538
II+ GP G+ + +L N+ +F SA + + + + V+ F +
Sbjct 2 IIIISGPPGSGKTSVAIKLANELSYKFISAGKIFRDIAQKMGLDIINLNKVAESNFDIDK 61
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+ F +++ K ++ + I++
Sbjct 62 MVDKKIF------------------EFILSE-KNLIIESHIAGWL---FREYTNIAIYLW 99
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTRE----------MEQNNGHYFDTAIV--NS 646
P + +A K + + +II++ ++ N+ FD I N
Sbjct 100 AP-LKIRANRIAIRDKISYDQAISQIIKREYMHYKRFNKFYGIDINDLSVFDLVINTSNV 158
Query 647 DLDKAYQELLRLINKLDTEPQ 667
D++ + +L ++ + PQ
Sbjct 159 DVNNIVKLILTYLSSVSQNPQ 179
>sp|C3MQ86|KCY_SULIL Cytidylate kinase OS=Sulfolobus islandicus
(strain L.S.2.15 / Lassen #1) OX=429572 GN=cmk PE=3 SV=1
Length=189
Score = 38.9 bits (89), Expect = 0.057, Method: Composition-based stats.
Identities = 29/201 (14%), Positives = 67/201 (33%), Gaps = 37/201 (18%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF--EA 538
II+ GP G+ + +L N+ +F SA + + + + V+ F +
Sbjct 2 IIIISGPPGSGKTSVAIKLANELSYKFISAGKIFRDIAQKMGLDIINLNKVAESNFDIDK 61
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+ F +++ K ++ + I++
Sbjct 62 MVDKKIF------------------EFILSE-KNLIIESHIAGWL---FREYTNIAIYLW 99
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTRE----------MEQNNGHYFDTAIV--NS 646
P + +A K + + +II++ ++ N+ FD I N
Sbjct 100 AP-LKIRANRIAIRDKISYDQAISQIIKREYMHYKRFNKFYGIDINDLSVFDLVINTSNV 158
Query 647 DLDKAYQELLRLINKLDTEPQ 667
D++ + +L ++ + PQ
Sbjct 159 DVNNIVKLILTYLSSVSQNPQ 179
>sp|C4KHI3|KCY_SULIK Cytidylate kinase OS=Sulfolobus islandicus
(strain M.16.4 / Kamchatka #3) OX=426118 GN=cmk PE=3 SV=1
Length=189
Score = 38.9 bits (89), Expect = 0.057, Method: Composition-based stats.
Identities = 29/201 (14%), Positives = 67/201 (33%), Gaps = 37/201 (18%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF--EA 538
II+ GP G+ + +L N+ +F SA + + + + V+ F +
Sbjct 2 IIIISGPPGSGKTSVAIKLANELSYKFISAGKIFRDIAQKMGLDIINLNKVAESNFDIDK 61
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+ F +++ K ++ + I++
Sbjct 62 MVDKKIF------------------EFILSE-KNLIIESHIAGWL---FREYTNIAIYLW 99
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTRE----------MEQNNGHYFDTAIV--NS 646
P + +A K + + +II++ ++ N+ FD I N
Sbjct 100 AP-LKIRANRIAIRDKISYDQAISQIIKREYMHYKRFNKFYGIDINDLSVFDLVINTSNV 158
Query 647 DLDKAYQELLRLINKLDTEPQ 667
D++ + +L ++ + PQ
Sbjct 159 DVNNIVKLILTYLSSVSQNPQ 179
>sp|C3N5V4|KCY_SULIA Cytidylate kinase OS=Sulfolobus islandicus
(strain M.16.27) OX=427318 GN=cmk PE=3 SV=1
Length=189
Score = 38.9 bits (89), Expect = 0.057, Method: Composition-based stats.
Identities = 29/201 (14%), Positives = 67/201 (33%), Gaps = 37/201 (18%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF--EA 538
II+ GP G+ + +L N+ +F SA + + + + V+ F +
Sbjct 2 IIIISGPPGSGKTSVAIKLANELSYKFISAGKIFRDIAQKMGLDIINLNKVAESNFDIDK 61
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+ F +++ K ++ + I++
Sbjct 62 MVDKKIF------------------EFILSE-KNLIIESHIAGWL---FREYTNIAIYLW 99
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTRE----------MEQNNGHYFDTAIV--NS 646
P + +A K + + +II++ ++ N+ FD I N
Sbjct 100 AP-LKIRANRIAIRDKISYDQAISQIIKREYMHYKRFNKFYGIDINDLSVFDLVINTSNV 158
Query 647 DLDKAYQELLRLINKLDTEPQ 667
D++ + +L ++ + PQ
Sbjct 159 DVNNIVKLILTYLSSVSQNPQ 179
>sp|O94868|FCSD2_HUMAN F-BAR and double SH3 domains protein 2
OS=Homo sapiens OX=9606 GN=FCHSD2 PE=1 SV=3
Length=740
Score = 40.4 bits (93), Expect = 0.059, Method: Composition-based stats.
Identities = 21/102 (21%), Positives = 39/102 (38%), Gaps = 22/102 (22%)
Query 343 AKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVI---SQEDPNWWQAYREGDED 399
+V VKA +DY+ D LSF +G I+ ++ +Q+D +W+ G
Sbjct 565 GDASVCFVKALYDYEGQTDDE-------LSFPEGAIIRILNKENQDDDGFWEGEFNG--- 614
Query 400 NQPLAGLVPGKSFQQQREA------MKQTIEEDKEPEKSGKL 435
G+ P ++ + + I+ P+ L
Sbjct 615 ---RIGVFPSVLVEELSASENGDTPWMREIQISPSPKPHASL 653
>sp|Q62419|SH3G1_MOUSE Endophilin-A2 OS=Mus musculus OX=10090
GN=Sh3gl1 PE=1 SV=1
Length=368
Score = 40.0 bits (92), Expect = 0.060, Method: Composition-based stats.
Identities = 16/56 (29%), Positives = 30/56 (54%), Gaps = 7/56 (13%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGL 406
KA +D++P +D L F++GD++ + +Q D NW++ G PL+ +
Sbjct 312 KALYDFEPENDGE-------LGFREGDLITLTNQIDENWYEGMLHGQSGFFPLSYV 360
>sp|Q8YZH7|DER_NOSS1 GTPase Der OS=Nostoc sp. (strain PCC 7120
/ SAG 25.82 / UTEX 2576) OX=103690 GN=der PE=3 SV=1
Length=453
Score = 40.0 bits (92), Expect = 0.060, Method: Composition-based stats.
Identities = 33/200 (17%), Positives = 68/200 (34%), Gaps = 39/200 (20%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQ--EVAGRDYHFVSRQAFEAD 539
I +IG N G++ L +E+ S + TTR D E G++Y +
Sbjct 179 IAIIGRPNVGKSSLLNAFAGEER-VIVSPISGTTRDAIDTFIERDGQNYRLIDTAGIRKK 237
Query 540 IAAGKFIEHGEFEKNLYGTSIDSV------------RQ-------VINSGKICLLSLR-T 579
+ E + V Q +++ GK C++ +
Sbjct 238 KSIDYGTEFFSINRAFKAIRRADVVLLVIDALDGVTEQDQKLAGRILDEGKACVVVVNKW 297
Query 580 QSLKTLRNSDLKPYIIFIAPPSQERLRALLA-KEGKNP------KPEELREIIEKTREME 632
+++ Y I+ ++ L A L E + + + +I+E +
Sbjct 298 DAVEK------DSYTIY---DYEKNLEARLHFTEWADTIYVSAVTGQRVEKILELVTKAN 348
Query 633 QNNGHYFDTAIVNSDLDKAY 652
+ + T+++N L+ A
Sbjct 349 EEHKRRVSTSVINEVLEDAV 368
>sp|P70271|PDLI4_MOUSE PDZ and LIM domain protein 4 OS=Mus musculus
OX=10090 GN=Pdlim4 PE=1 SV=3
Length=330
Score = 40.0 bits (92), Expect = 0.061, Method: Composition-based stats.
Identities = 23/118 (19%), Positives = 36/118 (31%), Gaps = 3/118 (3%)
Query 257 VRIEKARDIPLGATVRNEMD-SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVN 315
V + + + ISR+ G A L GD + ING
Sbjct 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAAL-AALCPGDLIQAINGESTELMTHL 63
Query 316 EVFDLLSDMHGTLTFVL-IPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLS 372
E + + H LT + P + P + + H D + D R +S
Sbjct 64 EAQNRIKGCHDHLTLSVSRPENKNWPSAPDDKAQAHRIHIDPESQDCSPATSRRSSVS 121
>sp|A5AB13|NM111_ASPNC Pro-apoptotic serine protease nma111 OS=Aspergillus
niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC
A1513) OX=425011 GN=nma111 PE=3 SV=2
Length=1028
Score = 40.4 bits (93), Expect = 0.061, Method: Composition-based stats.
Identities = 20/116 (17%), Positives = 47/116 (41%), Gaps = 5/116 (4%)
Query 235 EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGL 294
EP+T + + + + + + + E ++ I+ G A+ G
Sbjct 279 EPVTRGTIQTQWILKPFDECRRLGLTPEWEATVRKAAPTETSMLVAEIILPEGPAD--GK 336
Query 295 LHEGDEVLEINGIEIRG-KDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIH 349
L EGD +L++NG+ + ++++ D S + T+ ++ Q + +H
Sbjct 337 LEEGDVLLQVNGVLLTQFIRLDDILD--SSVGQTVRLLVQRGGQNVEIECQVGDLH 390
>sp|O00160|MYO1F_HUMAN Unconventional myosin-If OS=Homo sapiens
OX=9606 GN=MYO1F PE=1 SV=3
Length=1098
Score = 40.4 bits (93), Expect = 0.061, Method: Composition-based stats.
Identities = 17/79 (22%), Positives = 30/79 (38%), Gaps = 14/79 (18%)
Query 336 QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYRE 395
+ KP P +A + Y D LSF +++ ++ ++ WW+
Sbjct 1033 GRPKPQPRTHGP-RCRALYQYVGQDVDE-------LSFNVNEVIEILMEDPSGWWKGRLH 1084
Query 396 GDEDNQPLAGLVPGKSFQQ 414
G E GL PG ++
Sbjct 1085 GQE------GLFPGNYVEK 1097
>sp|Q297U2|HTRA2_DROPS Serine protease HTRA2, mitochondrial OS=Drosophila
pseudoobscura pseudoobscura OX=46245 GN=HtrA2 PE=3
SV=1
Length=427
Score = 40.0 bits (92), Expect = 0.062, Method: Composition-based stats.
Identities = 20/63 (32%), Positives = 32/63 (51%), Gaps = 3/63 (5%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
N M V++ +++ G A SG L GD V IN EI+ +V+D L++ L V+
Sbjct 355 NLMHGVLVWKVIVGSPAH-SGGLQPGDIVTHINKKEIKNSS--DVYDALAEGRKDLEIVI 411
Query 333 IPS 335
+
Sbjct 412 LRG 414
>sp|B4G316|HTRA2_DROPE Serine protease HTRA2, mitochondrial OS=Drosophila
persimilis OX=7234 GN=HtrA2 PE=3 SV=1
Length=427
Score = 40.0 bits (92), Expect = 0.062, Method: Composition-based stats.
Identities = 20/63 (32%), Positives = 32/63 (51%), Gaps = 3/63 (5%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
N M V++ +++ G A SG L GD V IN EI+ +V+D L++ L V+
Sbjct 355 NLMHGVLVWKVIVGSPAH-SGGLQPGDIVTHINKKEIKNSS--DVYDALAEGRKDLEIVI 411
Query 333 IPS 335
+
Sbjct 412 LRG 414
>sp|O35964|SH3G1_RAT Endophilin-A2 OS=Rattus norvegicus OX=10116
GN=Sh3gl1 PE=1 SV=1
Length=368
Score = 40.0 bits (92), Expect = 0.062, Method: Composition-based stats.
Identities = 16/56 (29%), Positives = 30/56 (54%), Gaps = 7/56 (13%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGL 406
KA +D++P +D L F++GD++ + +Q D NW++ G PL+ +
Sbjct 312 KALYDFEPENDGE-------LGFREGDLITLTNQIDENWYEGMLHGQSGFFPLSYV 360
>sp|O14302|CYK3_SCHPO cytokinesis protein 3 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=cyk3 PE=1
SV=1
Length=886
Score = 40.4 bits (93), Expect = 0.063, Method: Composition-based stats.
Identities = 15/63 (24%), Positives = 23/63 (37%), Gaps = 11/63 (17%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
V+A + P + RE L F +GD++ +S D WW G+ P
Sbjct 11 VRALY-AWPGE------REGDLKFTEGDLIECLSIGDGKWWIGRHINTNT----QGIFPS 59
Query 410 KSF 412
Sbjct 60 NFV 62
>sp|Q6DD51|CSKI2_XENLA Caskin-2 OS=Xenopus laevis OX=8355 GN=caskin2
PE=2 SV=1
Length=1205
Score = 40.4 bits (93), Expect = 0.064, Method: Composition-based stats.
Identities = 23/140 (16%), Positives = 54/140 (39%), Gaps = 21/140 (15%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEI---NGIEIR-----GKDVNEVFDLLSDMHGTL 328
+ I+++ K G A L EV+++ NG+++ + ++ + + H ++
Sbjct 212 GIEINKVTKMGTALHEAALCGKTEVVKLLIENGVDVNIRNTYNQTALDIVNQFTTTHASI 271
Query 329 TFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPN 388
+ ++ V+A D+ + DP L+ + GD++ V+ Q
Sbjct 272 DIK-------QLLREASGILKVRALKDFWNAHDP------TALNIRAGDLITVLEQHPDG 318
Query 389 WWQAYREGDEDNQPLAGLVP 408
W+ + + G P
Sbjct 319 RWKGHIHDPQKGTDRVGFFP 338
>sp|A1CAL7|SHO1_ASPCL High osmolarity signaling protein sho1 OS=Aspergillus
clavatus (strain ATCC 1007 / CBS 513.65 / DSM
816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612 GN=sho1
PE=3 SV=1
Length=292
Score = 39.7 bits (91), Expect = 0.066, Method: Composition-based stats.
Identities = 20/78 (26%), Positives = 28/78 (36%), Gaps = 11/78 (14%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
Q + P E KA + YD + P +SF K +IL V WWQA +
Sbjct 223 QSQDEVPQPTEYPYRAKAIYSYDAN-----PEDANEISFSKHEILEVSDVS-GRWWQARK 276
Query 395 EGDEDNQPLAGLVPGKSF 412
+ G+ P
Sbjct 277 -----SSGETGIAPSNYL 289
>sp|Q5LR15|CCMA_RUEPO Cytochrome c biogenesis ATP-binding export
protein CcmA OS=Ruegeria pomeroyi (strain ATCC 700808 / DSM
15171 / DSS-3) OX=246200 GN=ccmA PE=3 SV=1
Length=204
Score = 38.9 bits (89), Expect = 0.066, Method: Composition-based stats.
Identities = 14/97 (14%), Positives = 21/97 (22%), Gaps = 12/97 (12%)
Query 463 ILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQE 522
I E +S P R +IL GP G+ L + L + +
Sbjct 15 IPVLEGLSFTLTP---GRALILRGPNGAGKTTLLRTLAGLQPPLAGRIEGAEDKIAYAGH 71
Query 523 VAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTS 559
G + T
Sbjct 72 SDGLK---------PTLSVTENLLFWAAVFGGRDITP 99
>sp|Q3USJ8|FCSD2_MOUSE F-BAR and double SH3 domains protein 2
OS=Mus musculus OX=10090 GN=Fchsd2 PE=1 SV=2
Length=740
Score = 40.4 bits (93), Expect = 0.066, Method: Composition-based stats.
Identities = 18/79 (23%), Positives = 33/79 (42%), Gaps = 16/79 (20%)
Query 343 AKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVI---SQEDPNWWQAYREGDED 399
+V VKA +DY+ D LSF +G I+ ++ +Q+D +W+ G
Sbjct 565 GDASVCFVKALYDYEGQTDDE-------LSFPEGAIIRILNKENQDDDGFWEGEFSG--- 614
Query 400 NQPLAGLVPGKSFQQQREA 418
G+ P ++ +
Sbjct 615 ---RIGVFPSVLVEELSAS 630
>sp|Q4FLN8|KAD_PELUB Adenylate kinase OS=Pelagibacter ubique (strain
HTCC1062) OX=335992 GN=adk PE=3 SV=1
Length=213
Score = 39.3 bits (90), Expect = 0.066, Method: Composition-based stats.
Identities = 17/66 (26%), Positives = 26/66 (39%), Gaps = 10/66 (15%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVA-GRDYHFVSRQAFEADI 540
IIL GP G+ Q ++ K + F + + R + G D E I
Sbjct 3 IILFGPPGAGKGTQAQSIVKKH-NYFQLSTGNLLRDEVKSKTDLGVD--------IEKLI 53
Query 541 AAGKFI 546
+ GKF+
Sbjct 54 SNGKFV 59
>sp|Q0AB37|DER_ALKEH GTPase Der OS=Alkalilimnicola ehrlichii (strain
ATCC BAA-1101 / DSM 17681 / MLHE-1) OX=187272 GN=der
PE=3 SV=1
Length=467
Score = 40.0 bits (92), Expect = 0.066, Method: Composition-based stats.
Identities = 19/99 (19%), Positives = 37/99 (37%), Gaps = 12/99 (12%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRR--DQEVAGRDYHFVSRQAFEAD 539
I ++G N G++ L RL+ +E+ +P TTR E GR Y +
Sbjct 184 IAIVGRPNVGKSTLVNRLLGEER-VLVYDMPGTTRDSVFIPLERDGRPYTLIDTAGMRRR 242
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
+ +E + L + + + + +L +
Sbjct 243 ARVHETVEKFSVIQTL---------KAMEAAHVVILVID 272
>sp|A7F1F4|SHO1_SCLS1 High osmolarity signaling protein sho1 OS=Sclerotinia
sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)
OX=665079 GN=sho1 PE=3 SV=1
Length=317
Score = 39.7 bits (91), Expect = 0.067, Method: Composition-based stats.
Identities = 18/62 (29%), Positives = 25/62 (40%), Gaps = 11/62 (18%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
KA + YD + D +SF K +IL V WWQA +E + G+ P
Sbjct 264 KAIYSYDANPDDA-----NEISFAKHEILEVSDVS-GRWWQAKKENGD-----TGIAPSN 312
Query 411 SF 412
Sbjct 313 YL 314
>sp|Q32IZ6|TAUB_SHIDS Taurine import ATP-binding protein TauB
OS=Shigella dysenteriae serotype 1 (strain Sd197) OX=300267
GN=tauB PE=3 SV=1
Length=255
Score = 39.3 bits (90), Expect = 0.067, Method: Composition-based stats.
Identities = 18/133 (14%), Positives = 40/133 (30%), Gaps = 22/133 (17%)
Query 464 LTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV 523
E+++L ++++GP CG+ L + + S R
Sbjct 15 PALEDINL---TLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSIQLAGKRIEGPGAE 71
Query 524 AGRDYHFVSRQAFEADIAAGKFIEHGEFEKNL-YGTSIDSVRQVINSGKICLLSLRTQSL 582
G F+ + + N+ +G + + ++ L + Q L
Sbjct 72 RGV--------VFQ----NEGLLPWRNVQDNVAFGLQLAGIEKMQR------LEIAYQML 113
Query 583 KTLRNSDLKPYII 595
K + + I
Sbjct 114 KKVGLEGAEKRYI 126
>sp|A5IZC6|KTHY_MYCAP Thymidylate kinase OS=Mycoplasmopsis agalactiae
(strain NCTC 10123 / CIP 59.7 / PG2) OX=347257 GN=tmk
PE=3 SV=1
Length=215
Score = 39.3 bits (90), Expect = 0.068, Method: Composition-based stats.
Identities = 33/203 (16%), Positives = 62/203 (31%), Gaps = 39/203 (19%)
Query 489 NCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEH 548
G+ + Q+L+ K ++ + TR + V + I +
Sbjct 10 GSGKTTIVQKLVEKLLEKKPALSFIVTREPGGKNV-------RESEKIRELILDKESRLS 62
Query 549 GEFEKNLYGTSI-----DSVRQVINSGKICLLS--LR----TQS---------LKTLRNS 588
E LY S + + K+ L + Q K L
Sbjct 63 PISEALLYTASRRIHIEKVILPALKENKLVLCDRYIDSFYAYQGIVRGLGLSFAKQLTEM 122
Query 589 DLK----PYIIFI-APPSQERLRA---LLAKEGKNPKP-EELREIIEKTREMEQNNGHYF 639
++ IFI Q R L + + + E +++ + +E+ + F
Sbjct 123 VIESTIPDITIFIDITAEQSEYRRNVSRLISDRLDSESLEFHKKVFDAYKEVINLDPKRF 182
Query 640 DTAIVNSDLDKAYQELLRLINKL 662
IVN L + L ++ KL
Sbjct 183 --IIVNG-LQSIPEILDEIVEKL 202
>sp|Q9R144|ANM2_MOUSE Protein arginine N-methyltransferase 2 OS=Mus
musculus OX=10090 GN=Prmt2 PE=1 SV=1
Length=448
Score = 40.0 bits (92), Expect = 0.068, Method: Composition-based stats.
Identities = 22/97 (23%), Positives = 33/97 (34%), Gaps = 26/97 (27%)
Query 321 LSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILH 380
L L L P + + A DY +D E LSF +G+ +
Sbjct 31 LLQDGAQLQLQLQPEEFV-------------AIADYTATD-------ETQLSFLRGEKIL 70
Query 381 VISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQRE 417
++ Q +WW R G G +P +Q E
Sbjct 71 ILRQTTADWWWGERAG------CCGYIPANHLGKQLE 101
>sp|Q4FTW3|DER_PSYA2 GTPase Der OS=Psychrobacter arcticus (strain
DSM 17307 / VKM B-2377 / 273-4) OX=259536 GN=der PE=3 SV=1
Length=473
Score = 40.0 bits (92), Expect = 0.070, Method: Composition-based stats.
Identities = 18/103 (17%), Positives = 40/103 (39%), Gaps = 12/103 (12%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQA 535
R + +IG N G++ L RL+ +++ +P TTR + G+DY +
Sbjct 176 RGLKLAIIGRPNVGKSTLVNRLLGEDR-VVVFDMPGTTRDSIYIPYKRDGKDYVLIDTAG 234
Query 536 FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
+ +E I +++ + +S ++ +
Sbjct 235 VRRRGKIDEKVEKFSV--------IKTLQAIEDSNVTVIV-ID 268
>sp|Q58914|Y1519_METJA Uncharacterized protein MJ1519 OS=Methanocaldococcus
jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1
/ JCM 10045 / NBRC 100440) OX=243232 GN=MJ1519 PE=4 SV=1
Length=1175
Score = 40.4 bits (93), Expect = 0.071, Method: Composition-based stats.
Identities = 33/178 (19%), Positives = 62/178 (35%), Gaps = 26/178 (15%)
Query 443 KKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPAN----RKRPIILIGPQNCGQNELRQR 498
+++ ++ K DNEE YE+ A + R IL GP G+ + +
Sbjct 542 REKLRIKNENKKPAGVDNEE---YEKALDMQTEAVVNLLKNRVGILTGPAGTGKTTVIKT 598
Query 499 LMNKEKDRFASAVPH--TTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLY 556
+M K+ + T + V + + + + IA +F ++ E N +
Sbjct 599 IMELMKEVLGLNKIYILTPTGKSAMVVNEKLNNLATAKTIHRYIAE-EFKDYFE-GDNYF 656
Query 557 GTSIDSVRQVINSGKICLL-------SLRTQSLKTLRNSDLK--PYIIFI-----APP 600
+D + L+ + T + L L Y+IF+ PP
Sbjct 657 ILRLDKITGNDKKEIDALIIDESSMVDIETMG-RLLGTIKLDNLKYLIFVGDINQLPP 713
>sp|E5AD87|SHO1_LEPMJ High osmolarity signaling protein SHO1 OS=Leptosphaeria
maculans (strain JN3 / isolate v23.1.3 / race
Av1-4-5-6-7-8) OX=985895 GN=SHO1 PE=3 SV=1
Length=336
Score = 39.7 bits (91), Expect = 0.071, Method: Composition-based stats.
Identities = 18/62 (29%), Positives = 25/62 (40%), Gaps = 11/62 (18%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
KA + Y+ + D +SFQK D+L V WWQA + E G+ P
Sbjct 283 KAIYSYEANPDDA-----NEISFQKHDVLEVSDVS-GRWWQAKKPNGE-----TGIAPSN 331
Query 411 SF 412
Sbjct 332 YL 333
>sp|E1BJW1|HTRA4_BOVIN Serine protease HTR4 OS=Bos taurus OX=9913
GN=HTRA4 PE=3 SV=1
Length=484
Score = 40.0 bits (92), Expect = 0.071, Method: Composition-based stats.
Identities = 15/63 (24%), Positives = 32/63 (51%), Gaps = 4/63 (6%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
V + +++G AAE SG L + D ++ ING+ + +V + + + +L+ ++
Sbjct 415 SGVFVHEVIQGTAAESSG-LKDHDVIVSINGLPVTTTT--DVIEAVK-ANDSLSLLVRRK 470
Query 336 QQI 338
Q
Sbjct 471 SQT 473
>sp|Q69ZI1|SH3R1_MOUSE E3 ubiquitin-protein ligase SH3RF1 OS=Mus
musculus OX=10090 GN=Sh3rf1 PE=1 SV=2
Length=892
Score = 40.0 bits (92), Expect = 0.071, Method: Composition-based stats.
Identities = 36/189 (19%), Positives = 58/189 (31%), Gaps = 42/189 (22%)
Query 331 VLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW 390
++ P Q P KA +D++ D L F K D+L VI + D NW
Sbjct 190 IIKPLPQPPPQC--------KALYDFEVKDKEADKDC---LPFAKDDVLTVIRRVDENW- 237
Query 391 QAYREGDEDNQPLAGLVP---------GKSFQQQREAMKQTIEEDKEPEKSGKLWCA--- 438
+ G+ P K + + ++ + P + + A
Sbjct 238 -----AEGMLADKIGIFPISYVEFNSAAKQLIEWDKPPVPGVDTAECPSATAQSTSASKH 292
Query 439 ---KKNKKKRKKV--LYNANKNDDYDN--EEILTYEEMSLYHQ-PANRKRPIILIG---- 486
KKN +KR L ANK+ + + + P R L G
Sbjct 293 PDTKKNTRKRHSFTSLTMANKSSQGSQNRHSMEISPPVLISSSNPTAAARISELSGLSCS 352
Query 487 -PQNCGQNE 494
P +
Sbjct 353 APSQVHIST 361
>sp|O26342|RFCL_METTH Replication factor C large subunit OS=Methanothermobacter
thermautotrophicus (strain ATCC 29096 / DSM
1053 / JCM 10044 / NBRC 100330 / Delta H) OX=187420 GN=rfcL
PE=1 SV=1
Length=479
Score = 40.0 bits (92), Expect = 0.071, Method: Composition-based stats.
Identities = 28/156 (18%), Positives = 56/156 (36%), Gaps = 9/156 (6%)
Query 480 RPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
+P++L+GP G+ L + + D AG +R F D
Sbjct 39 KPLLLVGPPGTGKTTLAHIIGKEFSDTLELNASDRRSQDALMRSAGEAS--ATRSLFNHD 96
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKI--CLLSLRTQSLKTLRNSDLKPYIIF- 596
+ E N + ++ ++I + L + S K L++ + ++
Sbjct 97 LKLIILDEVDGIHGNEDRGGVQAINRIIKESRHPMVLTANDPYS-KRLQSIKPRCRVLNL 155
Query 597 --IAPPSQ-ERLRALLAKEGKNPKPEELREIIEKTR 629
+ S LR + EG + LRE+ +++R
Sbjct 156 RKVHTSSIAAALRRICRAEGIECPDDVLRELAKRSR 191
>sp|Q7U6R4|PSTB_PARMW Phosphate import ATP-binding protein PstB
OS=Parasynechococcus marenigrum (strain WH8102) OX=84588 GN=pstB
PE=3 SV=1
Length=273
Score = 39.3 bits (90), Expect = 0.071, Method: Composition-based stats.
Identities = 15/72 (21%), Positives = 25/72 (35%), Gaps = 10/72 (14%)
Query 465 TYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV- 523
+YE + + R + IGP CG++ + + L N+ D V
Sbjct 30 SYEAVKNVYCDVPRGKVTAFIGPSGCGKSTVLRAL-NRMNDLIEGCSLK-------GRVL 81
Query 524 -AGRDYHFVSRQ 534
G D + S
Sbjct 82 FDGVDLYGASVD 93
>sp|Q6CAC5|SHO1_YARLI High osmolarity signaling protein SHO1 OS=Yarrowia
lipolytica (strain CLIB 122 / E 150) OX=284591 GN=SHO1
PE=3 SV=1
Length=300
Score = 39.7 bits (91), Expect = 0.071, Method: Composition-based stats.
Identities = 18/63 (29%), Positives = 26/63 (41%), Gaps = 11/63 (17%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
+A + Y + P +SF KG+IL V WWQA R+ E G+ P
Sbjct 246 RAVYAYQAN-----PEDANEISFDKGEILDVSDIS-GRWWQARRDNGE-----IGICPSN 294
Query 411 SFQ 413
+
Sbjct 295 YVE 297
>sp|Q2NQJ1|AROK_SODGM Shikimate kinase 1 OS=Sodalis glossinidius
(strain morsitans) OX=343509 GN=aroK PE=3 SV=1
Length=173
Score = 38.5 bits (88), Expect = 0.073, Method: Composition-based stats.
Identities = 31/164 (19%), Positives = 59/164 (36%), Gaps = 17/164 (10%)
Query 479 KRPIILIGPQNCGQNELRQRLMNK-EKDRFASAVPHTTRSRRD----QEVAGRDYHFVSR 533
KR I L+GP G++ + ++L + + F S R+ D +V G D F R
Sbjct 4 KRNIFLVGPMGAGKSTIGRQLAQQLNMEFFDSDQEIERRTGADVGWVFDVEGED-GFRDR 62
Query 534 QA--FEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLS--LRTQSLKTLRNSD 589
+ + S ++ ++ G + L + Q +T R+
Sbjct 63 EEKVINELTEKQGIVLAT---GGGSVKSRETRNRLSARGVVVYLETTIEKQLARTQRDKK 119
Query 590 LKPYIIFIAPPSQERLRALLAKEGK--NPKPEELREIIEKTREM 631
+ APP +E L AL + + E++ ++
Sbjct 120 RPLLQV-EAPP-REVLEALARERNPLYEEIADVTIRTDEQSAKV 161
>sp|P0CR79|HSE1_CRYNB Class E vacuolar protein-sorting machinery
protein HSE1 OS=Cryptococcus neoformans var. neoformans serotype
D (strain B-3501A) OX=283643 GN=HSE1 PE=3 SV=1
Length=660
Score = 40.0 bits (92), Expect = 0.073, Method: Composition-based stats.
Identities = 18/100 (18%), Positives = 36/100 (36%), Gaps = 13/100 (13%)
Query 333 IPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 392
P + P T V+A + + + L F++GD++ V+ + WW+
Sbjct 245 QPLEPEPPRVDLNTATCVRAIYPFTGQEVGE-------LDFERGDVIKVLDRGFKEWWRG 297
Query 393 YREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKS 432
G G+ P + E + ++E + E
Sbjct 298 ACNGK------IGIFPVTYVEALPEPTPKELQEKAQEEAR 331
>sp|Q28E95|SH3R1_XENTR E3 ubiquitin-protein ligase SH3RF1 OS=Xenopus
tropicalis OX=8364 GN=sh3rf1 PE=2 SV=1
Length=861
Score = 40.0 bits (92), Expect = 0.073, Method: Composition-based stats.
Identities = 34/209 (16%), Positives = 60/209 (29%), Gaps = 27/209 (13%)
Query 331 VLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW 390
++ P Q P KA +D++ D L F K DIL VI + D NW
Sbjct 188 IIKPLPQPPPQC--------KALYDFEVKDKEADKDC---LPFLKDDILTVIRRVDENW- 235
Query 391 QAYREGDEDNQPLAGLVPGKSFQ-----QQREAMKQTIEEDKEPEKSGKLWCAKKNKKKR 445
+ G+ P + +Q + + D SG + K+
Sbjct 236 -----AEGMLGDKIGIFPISYVEFNSAAKQLIELDKPSGVDTGEGSSGTTHSSNSQKQAD 290
Query 446 KKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIG--PQNCGQNELRQRLMNKE 503
K + + + + H P+++ P + L
Sbjct 291 AKKNTKKRHSFTSLTMSNKSSQSVQNRHSMEISP-PVLISSSNPTAAARISELTGLSCSA 349
Query 504 KDRFASAVP--HTTRSRRDQEVAGRDYHF 530
+ + T V+G + F
Sbjct 350 PSQVHISTTGLIVTPPPSSPVVSGPAFTF 378
>sp|Q2SL36|DEGPL_HAHCH Probable periplasmic serine endoprotease
DegP-like OS=Hahella chejuensis (strain KCTC 2396) OX=349521
GN=mucD PE=3 SV=1
Length=469
Score = 40.0 bits (92), Expect = 0.077, Method: Composition-based stats.
Identities = 22/100 (22%), Positives = 43/100 (43%), Gaps = 14/100 (14%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLL--SDMHGTLTF 330
N+ ++++++KG A+K+G L GD ++ NG EI G +E+ L+ + +
Sbjct 284 NKPRGALVAQVMKGSPADKAG-LQPGDVIVSYNGNEI-GLS-SELPHLVGRTSPGQKASM 340
Query 331 VLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELG 370
++ + + V P+DD V G
Sbjct 341 KVV---------RRGDEMDVAVEIGQLPADDNGVASVPAG 371
>sp|Q80Z38|SHAN2_MOUSE SH3 and multiple ankyrin repeat domains
protein 2 OS=Mus musculus OX=10090 GN=Shank2 PE=1 SV=2
Length=1476
Score = 40.0 bits (92), Expect = 0.077, Method: Composition-based stats.
Identities = 17/102 (17%), Positives = 37/102 (36%), Gaps = 16/102 (16%)
Query 255 KIVRIEKARDIPLGATVRNEMDSV---------------IISRIVKGGAAEKSGLLHEGD 299
K V ++K + G +R + + +GG A ++G L GD
Sbjct 246 KTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAG-LRTGD 304
Query 300 EVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
++E+N + +V +++ L ++ + P
Sbjct 305 FLIEVNNENVVKVGHRQVVNMIRQGGNHLILKVVTVTRNLDP 346
>sp|Q3M929|DER_TRIV2 GTPase Der OS=Trichormus variabilis (strain
ATCC 29413 / PCC 7937) OX=240292 GN=der PE=3 SV=1
Length=453
Score = 39.7 bits (91), Expect = 0.078, Method: Composition-based stats.
Identities = 33/201 (16%), Positives = 68/201 (34%), Gaps = 39/201 (19%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQ--EVAGRDYHFVSRQAFEAD 539
I +IG N G++ L +E+ S + TTR D E G++Y +
Sbjct 179 IAIIGRPNVGKSSLLNAFAGEER-VIVSPISGTTRDAIDTFIERNGQNYRLIDTAGIRKK 237
Query 540 IAAGKFIEHGEFEKNLYGTSIDSV------------RQ-------VINSGKICLLSLR-T 579
+ E + V Q +++ GK C++ +
Sbjct 238 KSIDYGTEFFSINRAFKAIRRADVVLLVIDALDGVTEQDQKLAGRILDEGKACVVVVNKW 297
Query 580 QSLKTLRNSDLKPYIIFIAPPSQERLRALLA-KEGKNP------KPEELREIIEKTREME 632
+++ Y I+ ++ L A L E + + + +I+E +
Sbjct 298 DAVEK------DSYTIY---DYEKNLEARLHFTEWADTIYVSAVTGQRVEKILELVTKAN 348
Query 633 QNNGHYFDTAIVNSDLDKAYQ 653
+ + T+++N L+ A
Sbjct 349 EEHKRRVSTSVINEVLEDAVS 369
>sp|A5IMD9|DER_THEP1 GTPase Der OS=Thermotoga petrophila (strain
ATCC BAA-488 / DSM 13995 / JCM 10881 / RKU-1) OX=390874 GN=der
PE=3 SV=1
Length=439
Score = 39.7 bits (91), Expect = 0.082, Method: Composition-based stats.
Identities = 20/53 (38%), Positives = 30/53 (57%), Gaps = 3/53 (6%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV--AGRDYHFVS 532
+ ++G N G++ L ++NKE+ S +P TTR D+EV GR Y FV
Sbjct 183 VAIVGRPNVGKSTLFNAILNKER-ALVSPIPGTTRDPVDEEVFIDGRKYVFVD 234
>sp|K0E4D9|ECDL_ASPRU ABC transporter ecdL OS=Aspergillus rugulosus
OX=41736 GN=ecdL PE=1 SV=1
Length=1479
Score = 40.0 bits (92), Expect = 0.083, Method: Composition-based stats.
Identities = 20/133 (15%), Positives = 46/133 (35%), Gaps = 13/133 (10%)
Query 394 REGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKV--LYN 451
+E E + G+ + ++ + + + + + + +
Sbjct 550 KEAPEPSPNKPGVASTEGLVAWSASLDEPGLDPRVEMRRMSSLQHRFYNLGELQDGLIVL 609
Query 452 ANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAV 511
N ++ ++++ R +I+IGP G++ L ++ + V
Sbjct 610 QNHTASWEKASKPVLTDINV---TITRGSFVIVIGPIGSGKSTLLHSILGE--------V 658
Query 512 PHTTRSRRDQEVA 524
PHTT R QEV
Sbjct 659 PHTTGIRTIQEVD 671
>sp|Q8PXV5|KTHY_METMA Probable thymidylate kinase OS=Methanosarcina
mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM
11833 / OCM 88) OX=192952 GN=tmk PE=3 SV=1
Length=206
Score = 38.9 bits (89), Expect = 0.084, Method: Composition-based stats.
Identities = 16/99 (16%), Positives = 35/99 (35%), Gaps = 8/99 (8%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R + I L G G++ + +++ +E P TR + G + +
Sbjct 2 RGKLITLEGIDGSGKSTVAKKI--QENPEIQVFDPVFTREPTRGTLTGTAVENAIQSETD 59
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLS 576
A F+ + ++L V+ + +GK +
Sbjct 60 QL--AELFLFTADHAEHL----AKLVKPALANGKNVISD 92
>sp|P32641|RAD24_YEAST Checkpoint protein RAD24 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RAD24
PE=1 SV=1
Length=659
Score = 40.0 bits (92), Expect = 0.084, Method: Composition-based stats.
Identities = 16/157 (10%), Positives = 51/157 (32%), Gaps = 31/157 (20%)
Query 418 AMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQ--- 474
+ + ++ + + +K++ + + Y+ + E+++++ +
Sbjct 27 SSSRPTSPVRKARSTENDFLSKQDTSSILPSINDDGGEQWYEKFKPNCLEQVAIHKRKLK 86
Query 475 -----------PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV 523
P + R ++L GP C ++ + + L ++ T+ E
Sbjct 87 DVQEALDAMFLPNAKHRILLLSGPSGCSKSTVIKELSKILVPKYRQNSNGTSFRSTPNE- 145
Query 524 AGRDYHFVSRQAFE---------ADIAAGKFIEHGEF 551
H V+ F + +F++ +
Sbjct 146 -----HKVT--EFRGDCIVNDLPQMESFSEFLKGARY 175
>sp|Q9X1F8|DER_THEMA GTPase Der OS=Thermotoga maritima (strain
ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) OX=243274
GN=der PE=1 SV=1
Length=439
Score = 39.7 bits (91), Expect = 0.085, Method: Composition-based stats.
Identities = 20/53 (38%), Positives = 29/53 (55%), Gaps = 3/53 (6%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV--AGRDYHFVS 532
+ ++G N G++ L ++NKE+ S +P TTR D EV GR Y FV
Sbjct 183 VAIVGRPNVGKSTLFNAILNKER-ALVSPIPGTTRDPVDDEVFIDGRKYVFVD 234
>sp|O82500|Y4117_ARATH Putative disease resistance protein At4g11170
OS=Arabidopsis thaliana OX=3702 GN=At4g11170 PE=2 SV=1
Length=1095
Score = 40.0 bits (92), Expect = 0.085, Method: Composition-based stats.
Identities = 26/183 (14%), Positives = 63/183 (34%), Gaps = 15/183 (8%)
Query 413 QQQREAMKQTIEEDK---EPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEE- 468
++++ ++ + + A K K VL N D +++ E
Sbjct 131 EERQHNWRRALTDAANILGDHPQNWDNEAYKITTISKDVLEKLNATPSRDFNDLVGMEAH 190
Query 469 ----MSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVA 524
SL + R + + GP G+ + + L N+ + F ++ E
Sbjct 191 IAKMESLLCLESQGVRIVGIWGPAGVGKTTIARALYNQYHENFNLSIFMENVRESYGEAG 250
Query 525 GRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKT 584
DY +F+ +K+L + ++ + + S K+ ++ +++
Sbjct 251 LDDYG-------LKLHLQQRFLSKLLDQKDLRVRHLGAIEERLKSQKVLIILDDVDNIEQ 303
Query 585 LRN 587
L+
Sbjct 304 LKA 306
>sp|C4ZD63|DER_AGARV GTPase Der OS=Agathobacter rectalis (strain
ATCC 33656 / DSM 3377 / JCM 17463 / KCTC 5835 / VPI 0990)
OX=515619 GN=der PE=3 SV=1
Length=441
Score = 39.7 bits (91), Expect = 0.086, Method: Composition-based stats.
Identities = 18/84 (21%), Positives = 36/84 (43%), Gaps = 4/84 (5%)
Query 466 YEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV-- 523
+ + S +R R + ++G N G++ L +L +++ S + TTR D +
Sbjct 165 FPDSSKQDDEDDRPR-VAIVGKPNVGKSSLINKLAREDR-VIVSDIAGTTRDAIDTAIKY 222
Query 524 AGRDYHFVSRQAFEADIAAGKFIE 547
G++Y F+ + IE
Sbjct 223 DGKEYIFIDTAGLRRKNKIKEDIE 246
>sp|B4LY58|HTRA2_DROVI Serine protease HTRA2, mitochondrial OS=Drosophila
virilis OX=7244 GN=HtrA2 PE=3 SV=1
Length=421
Score = 39.7 bits (91), Expect = 0.086, Method: Composition-based stats.
Identities = 19/60 (32%), Positives = 30/60 (50%), Gaps = 3/60 (5%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
V++ +++ G A SG L GD V IN EI+ +V+D L+D L V++
Sbjct 352 HGVLVWKVIVGSPAH-SGGLQPGDIVTHINKKEIKNSS--DVYDALADGKKELDIVILRG 408
>sp|A6UDM2|ATPG_SINMW ATP synthase gamma chain OS=Sinorhizobium
medicae (strain WSM419) OX=366394 GN=atpG PE=3 SV=1
Length=291
Score = 39.3 bits (90), Expect = 0.087, Method: Composition-based stats.
Identities = 24/117 (21%), Positives = 43/117 (37%), Gaps = 26/117 (22%)
Query 560 IDSVRQVINSGKIC-LLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKP 618
D VR+++ GK ++ + + LR I + LR + K G
Sbjct 103 RDHVRKLLAQGKTVKIICVGKKGFDILRREFASLII------DRVDLRE-VKKIGFENAD 155
Query 619 EELREIIEKTREMEQNNGHYFDTAIVNSDLDKA---YQELLRLINKLDTEPQWVPST 672
++IE FD N + D Y E +I+++ T Q +P++
Sbjct 156 RIGHKVIE-----------LFD----NGEFDVCTLFYSEFKSVISQIPTAQQLIPAS 197
>sp|B4K835|HTRA2_DROMO Serine protease HTRA2, mitochondrial OS=Drosophila
mojavensis OX=7230 GN=HtrA2 PE=3 SV=1
Length=430
Score = 39.7 bits (91), Expect = 0.087, Method: Composition-based stats.
Identities = 19/60 (32%), Positives = 30/60 (50%), Gaps = 3/60 (5%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
V++ +++ G A SG L GD V IN EI+ +V+D L+D L V++
Sbjct 361 HGVLVWKVIVGSPAH-SGGLQPGDIVTHINKKEIKNSS--DVYDALADGKKELDIVILRG 417
>sp|P50479|PDLI4_HUMAN PDZ and LIM domain protein 4 OS=Homo sapiens
OX=9606 GN=PDLIM4 PE=1 SV=2
Length=330
Score = 39.3 bits (90), Expect = 0.088, Method: Composition-based stats.
Identities = 21/110 (19%), Positives = 31/110 (28%), Gaps = 2/110 (2%)
Query 257 VRIEKARDIPLGATVRNEMD-SVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVN 315
V + + + ISR+ G A L GD + ING
Sbjct 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAAL-AALCPGDLIQAINGESTELMTHL 63
Query 316 EVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVP 365
E + + H LT + + P A + DP P
Sbjct 64 EAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSP 113
>sp|Q8AXU9|SH3G3_CHICK Endophilin-A3 OS=Gallus gallus OX=9031
GN=SH3GL3 PE=1 SV=1
Length=353
Score = 39.3 bits (90), Expect = 0.088, Method: Composition-based stats.
Identities = 16/63 (25%), Positives = 30/63 (48%), Gaps = 13/63 (21%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
+A +D++P + E L F++GDI+ + +Q D NW++ G +G P
Sbjct 297 QALYDFEPEN-------EGELGFKEGDIITLTNQIDENWYEGMLNG------ESGFFPHN 343
Query 411 SFQ 413
+
Sbjct 344 YVE 346
>sp|Q5ALV2|SLA1_CANAL Actin cytoskeleton-regulatory complex protein
SLA1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876)
OX=237561 GN=SLA1 PE=1 SV=1
Length=1257
Score = 40.0 bits (92), Expect = 0.088, Method: Composition-based stats.
Identities = 25/82 (30%), Positives = 33/82 (40%), Gaps = 14/82 (17%)
Query 332 LIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQ 391
L+PS I+ P +T A +DYD E LSF + D +V DP+W
Sbjct 63 LVPSTYIEEAPVIKTA---TALYDYDKQ-------TEEELSFNENDKFNVFDLNDPDW-- 110
Query 392 AYREGDEDNQPLAGLVPGKSFQ 413
GD + G VP Q
Sbjct 111 -ILVGDLAKEKF-GFVPSNYIQ 130
>sp|Q8I7C3|LASP1_DROME LIM and SH3 domain protein Lasp OS=Drosophila
melanogaster OX=7227 GN=Lasp PE=1 SV=2
Length=657
Score = 39.7 bits (91), Expect = 0.090, Method: Composition-based stats.
Identities = 18/82 (22%), Positives = 32/82 (39%), Gaps = 12/82 (15%)
Query 334 PSQQIKPPPAKETVIHV-KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 392
S + + T + V +A +DY+ D V SF++GD++ + D W
Sbjct 584 YSSLQEKQSRQSTAMRVYRAIYDYEAQDVDEV-------SFREGDVIFEVESIDSGWMTG 636
Query 393 YREGDEDNQPLAGLVPGKSFQQ 414
E G++P +Q
Sbjct 637 RVE----RTGKTGMLPANYVEQ 654
>sp|Q3U1V8|M3K9_MOUSE Mitogen-activated protein kinase kinase
kinase 9 OS=Mus musculus OX=10090 GN=Map3k9 PE=2 SV=2
Length=1077
Score = 40.0 bits (92), Expect = 0.092, Method: Composition-based stats.
Identities = 15/87 (17%), Positives = 31/87 (36%), Gaps = 18/87 (21%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE-----DPNWWQAYREGDEDNQPL 403
+ A F+Y+ + E L+ + GD++ V+S++ D WW
Sbjct 49 YWTAVFEYEAA-------GEDELTLRLGDVVEVLSKDSQVSGDEGWWTGQL------NQR 95
Query 404 AGLVPGKSFQQQREAMKQTIEEDKEPE 430
G+ P + + ++P
Sbjct 96 VGIFPSNYVTPRSAFSSRCQPGAEDPS 122
>sp|Q6NRD3|SH3R1_XENLA E3 ubiquitin-protein ligase SH3RF1 OS=Xenopus
laevis OX=8355 GN=sh3rf1 PE=1 SV=1
Length=826
Score = 39.7 bits (91), Expect = 0.095, Method: Composition-based stats.
Identities = 32/163 (20%), Positives = 54/163 (33%), Gaps = 24/163 (15%)
Query 331 VLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW 390
++ P Q P KA +D++ D L F K DIL VI + D NW
Sbjct 188 IIKPLPQPPPQC--------KALYDFEVKDKEADKDC---LPFLKDDILTVIRRVDENW- 235
Query 391 QAYREGDEDNQPLAGLVPGKSFQ-----QQREAMKQTIEEDKEPEKSGKLWCAKKNKKKR 445
+ G+ P + +Q + + D SG N +K+
Sbjct 236 -----AEGMLGDKIGIFPISYVEFNSAAKQLIELDKPSGADTGEGSSGTSHSG--NSQKQ 288
Query 446 KKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQ 488
N K + + + S+ ++ + P +LI
Sbjct 289 ADAKKNTKKRHSFTSLTMSNKSSQSVQNRHSMEISPPVLISSS 331
>sp|A0A1P8AUY4|MDN1_ARATH Midasin OS=Arabidopsis thaliana OX=3702
GN=MDN1 PE=1 SV=1
Length=5400
Score = 40.0 bits (92), Expect = 0.095, Method: Composition-based stats.
Identities = 12/38 (32%), Positives = 25/38 (66%), Gaps = 3/38 (8%)
Query 465 TYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNK 502
++E +SL ++KRP++L GP G++ L ++L ++
Sbjct 342 SFEMVSLA---VSQKRPVLLYGPSGSGKSALIRKLADE 376
>sp|Q1BUV6|MSBA_BURO1 ATP-dependent lipid A-core flippase OS=Burkholderia
orbicola (strain AU 1054) OX=331271 GN=msbA PE=3
SV=2
Length=593
Score = 39.7 bits (91), Expect = 0.096, Method: Composition-based stats.
Identities = 31/179 (17%), Positives = 57/179 (32%), Gaps = 40/179 (22%)
Query 408 PGKSFQQQREAMKQTI----------EEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDD 457
P K + +++ + +E EP+ G+ + + + + V + D
Sbjct 307 PLKHLIDVNQPLQRGMTAAELIFGLIDEPAEPQGGGRPLSQARGEIEFRAVSF------D 360
Query 458 YDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRS 517
Y E T + +S P I L GP G+ L L
Sbjct 361 YGAAERPTLDRISFKVAP---GEMIALAGPSGSGKTTLVNLLPRFFD------------- 404
Query 518 RRDQE--VAGR---DYHFVSRQAFEADIAAGKFIEHGEFEKNL-YG-TS-IDSVRQVIN 568
D V G DY + ++ A ++ + + N+ YG T V+ +
Sbjct 405 PTDGTILVDGVPVSDYDLHALRSQMAMVSQDVVLFNDTIAANVAYGQTPDRARVQAALE 463
>sp|Q4R989|PDZD9_MACFA PDZ domain-containing protein 9 OS=Macaca
fascicularis OX=9541 GN=PDZD9 PE=2 SV=1
Length=264
Score = 38.9 bits (89), Expect = 0.096, Method: Composition-based stats.
Identities = 16/85 (19%), Positives = 33/85 (39%), Gaps = 0/85 (0%)
Query 265 IPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDM 324
+ LG + + I+ +++ GAA G L GD ++ + + G + E LL +
Sbjct 38 LGLGLIIIQHGPYLQITHLIRKGAAANDGKLQPGDVLISVGYANVLGYTLREFLQLLQHI 97
Query 325 HGTLTFVLIPSQQIKPPPAKETVIH 349
+ + P + I+
Sbjct 98 TVGTVLQIKVYRDFINIPEEWLEIY 122
>sp|B1LBI4|DER_THESQ GTPase Der OS=Thermotoga sp. (strain RQ2)
OX=126740 GN=der PE=3 SV=1
Length=439
Score = 39.7 bits (91), Expect = 0.097, Method: Composition-based stats.
Identities = 19/60 (32%), Positives = 30/60 (50%), Gaps = 3/60 (5%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV--AGRDYHFVSRQAFEAD 539
+ ++G N G++ L ++NKE+ S +P TTR D+EV G+ Y FV
Sbjct 183 VAIVGRPNVGKSTLFNAILNKER-ALVSPIPGTTRDPVDEEVFIDGKKYVFVDTAGLRRR 241
>sp|B3QS35|ENGB_CHLT3 Probable GTP-binding protein EngB OS=Chloroherpeton
thalassium (strain ATCC 35110 / GB-78) OX=517418
GN=engB PE=3 SV=1
Length=193
Score = 38.5 bits (88), Expect = 0.098, Method: Composition-based stats.
Identities = 21/68 (31%), Positives = 29/68 (43%), Gaps = 2/68 (3%)
Query 466 YEEMSLYHQPANRKRP-IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVA 524
Y+ ++ P I G N G++ L LM K+ ASA P TR V
Sbjct 9 YKSVTRLEDLPKDGLPEIAFAGRSNVGKSSLMNTLMGKKDLARASATPGKTREINFFLVN 68
Query 525 GRDYHFVS 532
G+ Y+FV
Sbjct 69 GK-YYFVD 75
>sp|B1J4D7|DEGPL_PSEPW Probable periplasmic serine endoprotease
DegP-like OS=Pseudomonas putida (strain W619) OX=390235 GN=PputW619_1070
PE=3 SV=1
Length=479
Score = 39.7 bits (91), Expect = 0.098, Method: Composition-based stats.
Identities = 17/83 (20%), Positives = 35/83 (42%), Gaps = 8/83 (10%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIE-IRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+++++++ G A KSG L GD +L +NG + D+ + L +I +
Sbjct 297 GALVAQVLEDGPAAKSG-LQVGDVILSMNGQPIVMSADLPHLVGTLK-AGAKAKLEIIRN 354
Query 336 QQIKPPPAKETVIHVKAHFDYDP 358
+ + + + A D D
Sbjct 355 GK-----RQNLDVTIGAMPDDDA 372
>sp|Q6BVC2|SHO1_DEBHA High osmolarity signaling protein SHO1 OS=Debaryomyces
hansenii (strain ATCC 36239 / CBS 767 / BCRC
21394 / JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=SHO1 PE=3
SV=1
Length=304
Score = 39.3 bits (90), Expect = 0.098, Method: Composition-based stats.
Identities = 18/62 (29%), Positives = 25/62 (40%), Gaps = 11/62 (18%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
KA + YD + P +SF K ++L V D WWQA R + G+ P
Sbjct 250 KALYSYDAN-----PEDINEISFAKDELLEV-DDIDGKWWQAKR-----SNGQVGICPSN 298
Query 411 SF 412
Sbjct 299 YV 300
>sp|Q66HA1|M3K11_RAT Mitogen-activated protein kinase kinase kinase
11 OS=Rattus norvegicus OX=10116 GN=Map3k11 PE=1 SV=1
Length=850
Score = 39.7 bits (91), Expect = 0.099, Method: Composition-based stats.
Identities = 20/86 (23%), Positives = 32/86 (37%), Gaps = 19/86 (22%)
Query 332 LIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE-----D 386
+ P K A + A FDY+P+ + L+ +KGD + V+S++ D
Sbjct 30 VRPEGSPKATAAYANPVW-TALFDYEPN-------GQDELALRKGDRVEVLSRDAAISGD 81
Query 387 PNWWQAYREGDEDNQPLAGLVPGKSF 412
WW G G+ P
Sbjct 82 EGWWAGQVGG------QVGIFPSNYV 101
>sp|Q30PC0|PSTB_SULDN Phosphate import ATP-binding protein PstB
OS=Sulfurimonas denitrificans (strain ATCC 33889 / DSM 1251)
OX=326298 GN=pstB PE=3 SV=1
Length=261
Score = 38.9 bits (89), Expect = 0.100, Method: Composition-based stats.
Identities = 15/63 (24%), Positives = 25/63 (40%), Gaps = 4/63 (6%)
Query 445 RKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEK 504
+KK L N Y ++ + + P + LIGP CG+ L + N+
Sbjct 9 KKKALEVKNFEFTYAKADVPS---VKKLSMPVAKHNITALIGPSGCGKTTLLRS-FNRMH 64
Query 505 DRF 507
D +
Sbjct 65 DLY 67
>sp|Q9QX74|SHAN2_RAT SH3 and multiple ankyrin repeat domains protein
2 OS=Rattus norvegicus OX=10116 GN=Shank2 PE=1 SV=2
Length=1474
Score = 40.0 bits (92), Expect = 0.100, Method: Composition-based stats.
Identities = 17/102 (17%), Positives = 37/102 (36%), Gaps = 16/102 (16%)
Query 255 KIVRIEKARDIPLGATVRNEMDSV---------------IISRIVKGGAAEKSGLLHEGD 299
K V ++K + G +R + + +GG A ++G L GD
Sbjct 247 KTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAG-LRTGD 305
Query 300 EVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPP 341
++E+N + +V +++ L ++ + P
Sbjct 306 FLIEVNNENVVKVGHRQVVNMIRQGGNHLVLKVVTVTRNLDP 347
>sp|A4FUC9|RHPN2_BOVIN Rhophilin-2 OS=Bos taurus OX=9913 GN=RHPN2
PE=2 SV=1
Length=686
Score = 39.7 bits (91), Expect = 0.10, Method: Composition-based stats.
Identities = 43/224 (19%), Positives = 79/224 (35%), Gaps = 26/224 (12%)
Query 125 EDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLIS 184
E S L S E ++ L L Q K H V ++ S +
Sbjct 379 EKCLSQLY--------SHMPEGLTPLATLKNVHQRQLLGKSHLCQAVTHHEESMREASLC 430
Query 185 NAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDE---- 240
+Q VL H + + T L + L A D V++ E ++E I +
Sbjct 431 KKLRNIDVLQEVLSAAHDRSQLKYTQLREDDDLLNLTDAPDIVSKTEREVEIIVPQFSKV 490
Query 241 RVYESIGQYGGETV----------KIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAE 290
V + + G +V + + A + LG T+R V + + +A
Sbjct 491 TVTDFFQKLGPLSVFSANKRWTAPRSIHFT-AEEGDLGFTLRGN-SPVQVHFLDPYCSAA 548
Query 291 KSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHG-TLTFVLI 333
+G EGD ++ I ++ + ++EV +L + ++
Sbjct 549 AAGT-KEGDYIVSIQDVDCKWLTLSEVMKMLKSFGQDDIEMKVV 591
>sp|Q54CL3|PEX13_DICDI Peroxisomal membrane protein PEX13 OS=Dictyostelium
discoideum OX=44689 GN=pex13 PE=3 SV=1
Length=570
Score = 39.7 bits (91), Expect = 0.10, Method: Composition-based stats.
Identities = 15/53 (28%), Positives = 24/53 (45%), Gaps = 7/53 (13%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQP 402
VKA ++++P +P + GDI++VI + NWW G P
Sbjct 398 VKAIYEFNPETTRDLP-------LRVGDIVNVIDKPHDNWWVGECNGLSGFFP 443
>sp|B3ETH9|MNME_AMOA5 tRNA modification GTPase MnmE OS=Amoebophilus
asiaticus (strain 5a2) OX=452471 GN=mnmE PE=3 SV=1
Length=455
Score = 39.3 bits (90), Expect = 0.10, Method: Composition-based stats.
Identities = 16/56 (29%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVA--GRDYHFVS 532
PI ++G N G++ L L+ +E+ S +P TTR + E+ G F+
Sbjct 219 GLPIAIVGKPNVGKSTLLNALLQEER-AIVSPIPGTTRDFIEAEINIGGIHCRFID 273
>sp|Q15052|ARHG6_HUMAN Rho guanine nucleotide exchange factor
6 OS=Homo sapiens OX=9606 GN=ARHGEF6 PE=1 SV=2
Length=776
Score = 39.7 bits (91), Expect = 0.10, Method: Composition-based stats.
Identities = 21/115 (18%), Positives = 45/115 (39%), Gaps = 17/115 (15%)
Query 310 RGKDVNEVFDLLSDMHGTLTFVL----IPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVP 365
R ++ ++ G ++ + S+ ++ + VKA F++ ++
Sbjct 121 RSSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTN----- 175
Query 366 CRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
E LS KGDI++V E+ WW+ G G P ++ + + +
Sbjct 176 --EDELSVCKGDIIYVTRVEEGGWWEGTLNG------RTGWFPSNYVREIKSSER 222
>sp|Q9KLQ5|FBPC_VIBCH Fe(3+) ions import ATP-binding protein FbpC
OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor
Inaba N16961) OX=243277 GN=fbpC PE=3 SV=1
Length=351
Score = 39.3 bits (90), Expect = 0.11, Method: Composition-based stats.
Identities = 30/195 (15%), Positives = 58/195 (30%), Gaps = 38/195 (19%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMN-KEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR 533
+ + L+GP CG+ + + + ++ + + R + F S
Sbjct 28 EIKKGSLVTLLGPSGCGKTTVLRLVAGLEKPTSGQIFIDGEDVTERSIQQRDICMVFQSY 87
Query 534 QAFEADIAAGKFIEHGEFEKNLYG-----TSIDSVRQVINSGKICLLSLRTQS-----LK 583
F +E YG + VRQ ++ L + + +
Sbjct 88 ALFPHM---------SLYENVAYGLKMLKLPSEEVRQRVDE---ALKIVDLEGMGERYVD 135
Query 584 TL-----------RNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREME 632
+ R LKP ++ P L A L + + E + + +
Sbjct 136 QISGGQQQRVALARALVLKPKVLLFDEP-LSNLDANLRRSMRETIRELQQRFDITSLYVT 194
Query 633 QNNGHYF---DTAIV 644
+ F DT IV
Sbjct 195 HDQAEAFAVSDTVIV 209
>sp|B6HR44|SHO1_PENRW High osmolarity signaling protein sho1 OS=Penicillium
rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951
/ Wisconsin 54-1255) OX=500485 GN=sho1 PE=3 SV=1
Length=291
Score = 38.9 bits (89), Expect = 0.11, Method: Composition-based stats.
Identities = 18/76 (24%), Positives = 28/76 (37%), Gaps = 16/76 (21%)
Query 337 QIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREG 396
Q P + I+ +D +P D + SF K +IL V WWQA ++
Sbjct 229 QPTEYPYRAKAIY---SYDANPEDANEI-------SFAKHEILEVSDVS-GRWWQARKQN 277
Query 397 DEDNQPLAGLVPGKSF 412
+ G+ P
Sbjct 278 GD-----TGIAPSNYL 288
>sp|Q86W24|NAL14_HUMAN NACHT, LRR and PYD domains-containing protein
14 OS=Homo sapiens OX=9606 GN=NLRP14 PE=1 SV=1
Length=1093
Score = 39.7 bits (91), Expect = 0.11, Method: Composition-based stats.
Identities = 32/191 (17%), Positives = 67/191 (35%), Gaps = 30/191 (16%)
Query 390 WQAYREGDEDNQPLAGLVPGKSFQQQREAMKQ--TIEEDKEPEKSGKLWCAKKNKKKRKK 447
W A G +D + AG Q+ +EA+ T ++ EK W KK+ + +
Sbjct 97 WSAQTIGPDDAK--AG-----ETQEDQEAVLGDGTEYRNRIKEKFCITW-DKKSLAGKPE 148
Query 448 VLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRF 507
++ D E L ++ QP + ++L G G+ L ++ +
Sbjct 149 DFHHGIAEKDRKLLEHLFDVDVKTGAQP----QIVVLQGAAGVGKTTLVRK----AMLDW 200
Query 508 ASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVI 567
A + R + + GR+ + + ++F I+ E + +++
Sbjct 201 AEGSLYQQRFKYVFYLNGREINQLKERSFAQLISKD----WPSTEG--------PIEEIM 248
Query 568 NSGKICLLSLR 578
L +
Sbjct 249 YQPSSLLFIID 259
>sp|O43464|HTRA2_HUMAN Serine protease HTRA2, mitochondrial OS=Homo
sapiens OX=9606 GN=HTRA2 PE=1 SV=2
Length=458
Score = 39.3 bits (90), Expect = 0.11, Method: Composition-based stats.
Identities = 14/68 (21%), Positives = 29/68 (43%), Gaps = 9/68 (13%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG--------KDVNEVFDLLSDMHGT 327
V+I +++ G A ++G L GD +L I ++ + +++ + T
Sbjct 389 HGVLIHKVILGSPAHRAG-LRPGDVILAIGEQMVQNAEDVYEAVRTQSQLAVQIRRGRET 447
Query 328 LTFVLIPS 335
LT + P
Sbjct 448 LTLYVTPE 455
>sp|Q59185|LON1_BORBU Lon protease 1 OS=Borreliella burgdorferi
(strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) OX=224326
GN=lon1 PE=3 SV=1
Length=806
Score = 39.7 bits (91), Expect = 0.11, Method: Composition-based stats.
Identities = 18/100 (18%), Positives = 39/100 (39%), Gaps = 1/100 (1%)
Query 429 PEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQ 488
P + K+ K + +K KK+L + + + I+ Y + + + I+L+GP
Sbjct 333 PWRDFKINFDKLDLQKSKKILDKTHYGMNEVKDRIIEYISVLKLRKT-QKGAIILLVGPP 391
Query 489 NCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDY 528
G+ + + + +F R + + R Y
Sbjct 392 GVGKTSIGAAIAKVLRTKFFRFSVGGMRDESEIKGHRRTY 431
>sp|Q96N96|SPT13_HUMAN Spermatogenesis-associated protein 13 OS=Homo
sapiens OX=9606 GN=SPATA13 PE=1 SV=1
Length=652
Score = 39.7 bits (91), Expect = 0.11, Method: Composition-based stats.
Identities = 13/73 (18%), Positives = 27/73 (37%), Gaps = 3/73 (4%)
Query 368 ELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDK 427
+ L F+ GD++ V+ + +WW E E P + + + Q E + +
Sbjct 163 DQELGFKAGDVIQVLEASNKDWWWGRSEDKEAWFPASFV---RLRVNQEELSENSSSTPS 219
Query 428 EPEKSGKLWCAKK 440
E + +
Sbjct 220 EEQDEEASQSRHR 232
>sp|Q80XI6|M3K11_MOUSE Mitogen-activated protein kinase kinase
kinase 11 OS=Mus musculus OX=10090 GN=Map3k11 PE=1 SV=1
Length=850
Score = 39.7 bits (91), Expect = 0.11, Method: Composition-based stats.
Identities = 20/86 (23%), Positives = 32/86 (37%), Gaps = 19/86 (22%)
Query 332 LIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE-----D 386
+ P K A + A FDY+P+ + L+ +KGD + V+S++ D
Sbjct 30 VRPEGSPKATAAYANPVW-TALFDYEPN-------GQDELALRKGDRVEVLSRDAAISGD 81
Query 387 PNWWQAYREGDEDNQPLAGLVPGKSF 412
WW G G+ P
Sbjct 82 EGWWAGQVGG------QVGIFPSNYV 101
>sp|P10569|MYSC_ACACA Myosin IC heavy chain OS=Acanthamoeba castellanii
OX=5755 GN=MIC PE=1 SV=1
Length=1168
Score = 39.7 bits (91), Expect = 0.11, Method: Composition-based stats.
Identities = 13/63 (21%), Positives = 28/63 (44%), Gaps = 13/63 (21%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
+A +D+ + L+F +G ++ VI++ +P+WW+ G G+ P
Sbjct 982 RALYDFAAENPDE-------LTFNEGAVVTVINKSNPDWWEGELNG------QRGVFPAS 1028
Query 411 SFQ 413
+
Sbjct 1029 YVE 1031
>sp|Q1QD14|DER_PSYCK GTPase Der OS=Psychrobacter cryohalolentis
(strain ATCC BAA-1226 / DSM 17306 / VKM B-2378 / K5) OX=335284
GN=der PE=3 SV=1
Length=480
Score = 39.3 bits (90), Expect = 0.11, Method: Composition-based stats.
Identities = 19/121 (16%), Positives = 44/121 (36%), Gaps = 17/121 (14%)
Query 460 NEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR- 518
++ + E + R + +IG N G++ L RL+ +++ +P TTR
Sbjct 163 TADMPSQENVV-----EPRGLKLAIIGRPNVGKSTLVNRLLGEDR-VVVFDMPGTTRDSI 216
Query 519 -RDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSL 577
G+DY + + +E I +++ + +S ++ +
Sbjct 217 YIPYTREGKDYVLIDTAGVRRRGKIDEKVEKFSV--------IKTLQAIEDSNVTVIV-I 267
Query 578 R 578
Sbjct 268 D 268
>sp|Q8KDS2|MIAA_CHLTE tRNA dimethylallyltransferase OS=Chlorobaculum
tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806
/ TLS) OX=194439 GN=miaA PE=3 SV=1
Length=329
Score = 38.9 bits (89), Expect = 0.11, Method: Composition-based stats.
Identities = 16/77 (21%), Positives = 30/77 (39%), Gaps = 10/77 (13%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPH---------TTRSRRDQEVAGRDYHFVS 532
++++GP G+ EL R+ + SA T + R + +HF+
Sbjct 7 LVILGPTASGKTELAFRIARQTGGEIISADSRQIYRGMDIGTAKPPR-WMLDEVKHHFID 65
Query 533 RQAFEADIAAGKFIEHG 549
++ +AG F E
Sbjct 66 KKEIGEPFSAGDFAEQA 82
>sp|Q8IZP0|ABI1_HUMAN Abl interactor 1 OS=Homo sapiens OX=9606
GN=ABI1 PE=1 SV=4
Length=508
Score = 39.3 bits (90), Expect = 0.11, Method: Composition-based stats.
Identities = 18/64 (28%), Positives = 27/64 (42%), Gaps = 13/64 (20%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
V A +DY D LSF +G I++VI + D W++ + GL PG
Sbjct 451 VVAIYDYTKDKDDE-------LSFMEGAIIYVIKKNDDGWYEGVC------NRVTGLFPG 497
Query 410 KSFQ 413
+
Sbjct 498 NYVE 501
>sp|Q99961|SH3G1_HUMAN Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1
PE=1 SV=1
Length=368
Score = 39.3 bits (90), Expect = 0.12, Method: Composition-based stats.
Identities = 16/56 (29%), Positives = 30/56 (54%), Gaps = 7/56 (13%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGL 406
KA +D++P +D L F +GD++ + +Q D NW++ +G PL+ +
Sbjct 312 KALYDFEPENDGE-------LGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLSYV 360
>sp|P80192|M3K9_HUMAN Mitogen-activated protein kinase kinase
kinase 9 OS=Homo sapiens OX=9606 GN=MAP3K9 PE=1 SV=3
Length=1104
Score = 39.7 bits (91), Expect = 0.12, Method: Composition-based stats.
Identities = 15/87 (17%), Positives = 31/87 (36%), Gaps = 18/87 (21%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE-----DPNWWQAYREGDEDNQPL 403
+ A F+Y+ + E L+ + GD++ V+S++ D WW
Sbjct 56 YWTAVFEYEAA-------GEDELTLRLGDVVEVLSKDSQVSGDEGWWTGQL------NQR 102
Query 404 AGLVPGKSFQQQREAMKQTIEEDKEPE 430
G+ P + + ++P
Sbjct 103 VGIFPSNYVTPRSAFSSRCQPGGEDPS 129
>sp|Q46DH6|KTHY_METBF Probable thymidylate kinase OS=Methanosarcina
barkeri (strain Fusaro / DSM 804) OX=269797 GN=tmk PE=3
SV=1
Length=205
Score = 38.1 bits (87), Expect = 0.12, Method: Composition-based stats.
Identities = 19/101 (19%), Positives = 37/101 (37%), Gaps = 12/101 (12%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R + I L G G++ + ++L ++ + P TR + G A E
Sbjct 2 RGKLITLEGIDGSGKSTVAEKL--QKNPEIKAFKPVFTREPTRGTLTG--------DAVE 51
Query 538 ADIAA--GKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLS 576
I + +F E F + ++ + +GKI +
Sbjct 52 KAIQSDTDQFAELFLFTADHAEHLAKLIKPALENGKIVISD 92
>sp|P58660|CAR10_MOUSE Caspase recruitment domain-containing protein
10 OS=Mus musculus OX=10090 GN=Card10 PE=1 SV=1
Length=1021
Score = 39.7 bits (91), Expect = 0.12, Method: Composition-based stats.
Identities = 40/259 (15%), Positives = 84/259 (32%), Gaps = 37/259 (14%)
Query 348 IHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDP---NWWQAYREGDEDNQPLA 404
+++A+F DP+ C + +IL ++ W+ +
Sbjct 698 FYIRANFSLPERSDPHALCVKAQ------EILRLVDPAHKRRQEWFCTRVDTLTLRDLDR 751
Query 405 GLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEIL 464
G VP QQ +++ +S + K+ + D +
Sbjct 752 GTVPNYQRAQQLLEVQEKYLISSR-HRSPRSNLKKRALGLVRPKPAGGTAGDSAEQLPAE 810
Query 465 TYEEMSLYHQPANRKRPIILIG--PQ----NCGQNELRQRLMNKEKDR--FASAVPHTTR 516
E+ +P + RP+++ P C L + L++ R F +
Sbjct 811 PCSELERSLKPYSLVRPLLVSALRPVVLLPECLAPRLIRNLLDLPSSRLDFQVCPAES-- 868
Query 517 SRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLS 576
+S + A G G+ I ++++ + K CLL
Sbjct 869 --------------LSGEEQCTSSAPGAPKAWPATAG--LGSRIRAIQESVGK-KHCLLE 911
Query 577 LRTQSLKTLRNSDLKPYII 595
L + ++ L +S++ P +I
Sbjct 912 LGARGVRELVHSEVYPIVI 930
>sp|A7MZE5|DER_VIBC1 GTPase Der OS=Vibrio campbellii (strain ATCC
BAA-1116) OX=2902295 GN=der PE=3 SV=1
Length=498
Score = 39.3 bits (90), Expect = 0.12, Method: Composition-based stats.
Identities = 28/143 (20%), Positives = 56/143 (39%), Gaps = 25/143 (17%)
Query 451 NANKNDDYDNEEILTYEEMSLYHQ-------PANRKRP------IILIGPQNCGQNELRQ 497
A++++D + E++ +E+ L + A KR + +IG N G++ L
Sbjct 168 LASESEDGEIEDLTEFEDEELAVEDYTEEDAEAEFKRLQDQPIKLAIIGRPNVGKSTLTN 227
Query 498 RLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNL 555
R++ +E+ +P TTR E GR+Y + + +E K
Sbjct 228 RILGEER-VVVYDMPGTTRDSIYIPMERDGREYVLIDTAGVRRRGRINETVEKFSVVK-- 284
Query 556 YGTSIDSVRQVINSGKICLLSLR 578
++ +V + LL +
Sbjct 285 ---TLKAVEDA----NVVLLVID 300
>sp|A0A125QXJ1|ABCB6_MESAU ATP-binding cassette sub-family B member
6 OS=Mesocricetus auratus OX=10036 GN=ABCB6 PE=2 SV=1
Length=842
Score = 39.3 bits (90), Expect = 0.12, Method: Composition-based stats.
Identities = 14/89 (16%), Positives = 32/89 (36%), Gaps = 11/89 (12%)
Query 413 QQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLY 472
+ + + E K+ +G L K + A+ + T +++S
Sbjct 561 MENMFDLLKEETEVKDVPGAGPLRFHKGQIEFENVHFSYADGRE--------TLQDVSFT 612
Query 473 HQPANRKRPIILIGPQNCGQNELRQRLMN 501
P + + L+GP G++ + + L
Sbjct 613 VMP---GQTVALVGPSGAGKSTILRLLFR 638
>sp|Q7VWL4|DER_BORPE GTPase Der OS=Bordetella pertussis (strain
Tohama I / ATCC BAA-589 / NCTC 13251) OX=257313 GN=der PE=3
SV=1
Length=451
Score = 39.3 bits (90), Expect = 0.12, Method: Composition-based stats.
Identities = 31/143 (22%), Positives = 56/143 (39%), Gaps = 15/143 (10%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
++G N G++ L L+ +E+ A +P TTR D E GR Y +
Sbjct 190 IVGRPNVGKSTLINTLLGEER-VIAFDMPGTTRDAIEIDFERDGRKYTLIDTA---GLRK 245
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
GK E E S+ Q I + + LL + Q+ + +++ + F+
Sbjct 246 RGKVFEAIEKF------SVIKTLQAIEASNVVLLMIDAQAEVSEQDAHIAG---FVLETG 296
Query 602 QERLRALLAKEGKNPKPEELREI 624
+ + A+ +G + E E
Sbjct 297 RAVVVAINKWDGLDSDQRERIER 319
>sp|Q7W6Q0|DER_BORPA GTPase Der OS=Bordetella parapertussis (strain
12822 / ATCC BAA-587 / NCTC 13253) OX=257311 GN=der PE=3
SV=1
Length=451
Score = 39.3 bits (90), Expect = 0.12, Method: Composition-based stats.
Identities = 31/143 (22%), Positives = 56/143 (39%), Gaps = 15/143 (10%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
++G N G++ L L+ +E+ A +P TTR D E GR Y +
Sbjct 190 IVGRPNVGKSTLINTLLGEER-VIAFDMPGTTRDAIEIDFERDGRKYTLIDTA---GLRK 245
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
GK E E S+ Q I + + LL + Q+ + +++ + F+
Sbjct 246 RGKVFEAIEKF------SVIKTLQAIEASNVVLLMIDAQAEVSEQDAHIAG---FVLETG 296
Query 602 QERLRALLAKEGKNPKPEELREI 624
+ + A+ +G + E E
Sbjct 297 RAVVVAINKWDGLDSDQRERIER 319
>sp|Q7WHN4|DER_BORBR GTPase Der OS=Bordetella bronchiseptica (strain
ATCC BAA-588 / NCTC 13252 / RB50) OX=257310 GN=der PE=3
SV=1
Length=451
Score = 39.3 bits (90), Expect = 0.12, Method: Composition-based stats.
Identities = 31/143 (22%), Positives = 56/143 (39%), Gaps = 15/143 (10%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
++G N G++ L L+ +E+ A +P TTR D E GR Y +
Sbjct 190 IVGRPNVGKSTLINTLLGEER-VIAFDMPGTTRDAIEIDFERDGRKYTLIDTA---GLRK 245
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
GK E E S+ Q I + + LL + Q+ + +++ + F+
Sbjct 246 RGKVFEAIEKF------SVIKTLQAIEASNVVLLMIDAQAEVSEQDAHIAG---FVLETG 296
Query 602 QERLRALLAKEGKNPKPEELREI 624
+ + A+ +G + E E
Sbjct 297 RAVVVAINKWDGLDSDQRERIER 319
>sp|O13736|SLA1_SCHPO Actin cytoskeleton-regulatory complex protein
sla1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)
OX=284812 GN=sla1 PE=1 SV=1
Length=1420
Score = 39.7 bits (91), Expect = 0.13, Method: Composition-based stats.
Identities = 14/74 (19%), Positives = 32/74 (43%), Gaps = 4/74 (5%)
Query 351 KAHFDYDPSD---DPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR-EGDEDNQPLAGL 406
K + Y+P + +P E +S + +I+ ++ + + +W+ R D+ G+
Sbjct 11 KVLYSYEPQEINPGEEIPENEREISIVEDEIVCLLEKGEDDWYLVKRNVNSNDDDEEIGI 70
Query 407 VPGKSFQQQREAMK 420
VP + + K
Sbjct 71 VPSNYITEAEPSTK 84
>sp|Q1QSE9|PSTB2_CHRSD Phosphate import ATP-binding protein PstB
2 OS=Chromohalobacter salexigens (strain ATCC BAA-138 / DSM
3043 / CIP 106854 / NCIMB 13768 / 1H11) OX=290398 GN=pstB2
PE=3 SV=1
Length=257
Score = 38.5 bits (88), Expect = 0.13, Method: Composition-based stats.
Identities = 24/109 (22%), Positives = 38/109 (35%), Gaps = 18/109 (17%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF--VSRQA 535
R R IGP CG++ L + L +R TR+ R + G+D H V
Sbjct 35 RHRVTAFIGPSGCGKSTLLRAL-----NRLHDLNDQVTRTGRI-RLEGQDIHAREVDVAE 88
Query 536 FEADI-----AAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRT 579
+ A F +E YG + +R+ +I +
Sbjct 89 LRRRVGMVFQAPNPF-PMSIYENVAYGLRLQGIRRKRELDEI----IEW 132
>sp|D6PVB5|SHO1B_HORWE High osmolarity signaling protein SHO1B
OS=Hortaea werneckii OX=91943 GN=SHO1B PE=3 SV=1
Length=320
Score = 38.9 bits (89), Expect = 0.13, Method: Composition-based stats.
Identities = 18/62 (29%), Positives = 25/62 (40%), Gaps = 11/62 (18%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
KA + Y+ + D +SF K +IL V WWQA +E E G+ P
Sbjct 267 KAIYSYEANPDDA-----NEISFHKHEILEVSDVS-GRWWQAKKENGE-----TGIAPSN 315
Query 411 SF 412
Sbjct 316 YL 317
>sp|A7TKW4|SLA1_VANPO Actin cytoskeleton-regulatory complex protein
SLA1 OS=Vanderwaltozyma polyspora (strain ATCC 22028 /
DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283
/ UCD 57-17) OX=436907 GN=SLA1 PE=3 SV=1
Length=1202
Score = 39.3 bits (90), Expect = 0.13, Method: Composition-based stats.
Identities = 16/66 (24%), Positives = 33/66 (50%), Gaps = 11/66 (17%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQED-PNWW--QAYREGDEDNQPLAGLV 407
KA ++Y+P + +E D+L+++ + + +WW + G + ++P AGLV
Sbjct 9 KAIYNYEPQTPDELTIQE-------DDLLYLLEKSNVDDWWTVKKRVIGSDIDEP-AGLV 60
Query 408 PGKSFQ 413
P +
Sbjct 61 PSNYVE 66
Score = 37.3 bits (85), Expect = 0.55, Method: Composition-based stats.
Identities = 17/64 (27%), Positives = 25/64 (39%), Gaps = 9/64 (14%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
VKA +DY +P + L F + D V +DP+W A G +PG
Sbjct 74 VKAVYDYHEVQNP-----DEELVFNENDTFDVYDDKDPDWILARSISTN----QFGFIPG 124
Query 410 KSFQ 413
+
Sbjct 125 NYVE 128
>sp|O35413|SRBS2_RAT Sorbin and SH3 domain-containing protein
2 OS=Rattus norvegicus OX=10116 GN=Sorbs2 PE=1 SV=2
Length=1196
Score = 39.3 bits (90), Expect = 0.14, Method: Composition-based stats.
Identities = 18/72 (25%), Positives = 35/72 (49%), Gaps = 7/72 (10%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
S++ + P KE + KA +D+ LSF+KGD ++++ + D NW++
Sbjct 949 SRERRGTPEKEVKLPAKAVYDFKAQTSKE-------LSFKKGDTVYILRKIDQNWYEGEH 1001
Query 395 EGDEDNQPLAGL 406
G P++ +
Sbjct 1002 HGRVGIFPISYV 1013
>sp|Q11RE0|MIAA_CYTH3 tRNA dimethylallyltransferase OS=Cytophaga
hutchinsonii (strain ATCC 33406 / DSM 1761 / CIP 103989 /
NBRC 15051 / NCIMB 9469 / D465) OX=269798 GN=miaA PE=3 SV=1
Length=304
Score = 38.5 bits (88), Expect = 0.14, Method: Composition-based stats.
Identities = 17/72 (24%), Positives = 27/72 (38%), Gaps = 8/72 (11%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASA--------VPHTTRSRRDQEVAGRDYHFVSR 533
I+++GP G+ L L + SA + T +E G ++FV
Sbjct 9 IVVVGPTAAGKTALAVSLAKRFNTAVLSADSRQVFKELSIGTAKATMEEQDGVPHYFVDS 68
Query 534 QAFEADIAAGKF 545
+ E AG F
Sbjct 69 ISIEESFNAGMF 80
>sp|P32793|YSC84_YEAST Protein YSC84 OS=Saccharomyces cerevisiae
(strain ATCC 204508 / S288c) OX=559292 GN=YSC84 PE=1 SV=2
Length=468
Score = 38.9 bits (89), Expect = 0.14, Method: Composition-based stats.
Identities = 12/45 (27%), Positives = 22/45 (49%), Gaps = 8/45 (18%)
Query 371 LSFQKGDILHVISQEDP--NWWQAYREGDEDNQPLAGLVPGKSFQ 413
L+F+KGD++ ++ + D +WW G E G+ P +
Sbjct 428 LAFKKGDVITILKKSDSQNDWWTGRTNGKE------GIFPANYVR 466
>sp|Q8C0T5|SI1L1_MOUSE Signal-induced proliferation-associated
1-like protein 1 OS=Mus musculus OX=10090 GN=Sipa1l1 PE=1 SV=2
Length=1782
Score = 39.3 bits (90), Expect = 0.14, Method: Composition-based stats.
Identities = 22/124 (18%), Positives = 47/124 (38%), Gaps = 11/124 (9%)
Query 246 IGQYGGETVKIVRIEKARDIPLGATVRNEMDSV---------IISRIVKGGAAEKSGLLH 296
G+ E V+ ++ + T+R I++ + G A ++G L
Sbjct 931 SGEDIKEIVRRLQFVSKGCESVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAG-LR 989
Query 297 EGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDY 356
+G ++EI + + ++ DLL T+ V+IP P + + +Y
Sbjct 990 QGSRLVEICKVAVATLSHEQMIDLLR-TSVTVKVVIIPPHDDCTPRRSCSETYRMPVMEY 1048
Query 357 DPSD 360
++
Sbjct 1049 QMNE 1052
>sp|Q2U7N9|SHO1_ASPOR High osmolarity signaling protein sho1 OS=Aspergillus
oryzae (strain ATCC 42149 / RIB 40) OX=510516
GN=sho1 PE=3 SV=1
Length=289
Score = 38.5 bits (88), Expect = 0.15, Method: Composition-based stats.
Identities = 18/76 (24%), Positives = 27/76 (36%), Gaps = 16/76 (21%)
Query 337 QIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREG 396
Q P + I+ +D +P D + SF K +IL V WWQA +
Sbjct 227 QPTEYPYRAKAIY---SYDANPEDANEI-------SFTKHEILEVSDVS-GRWWQARKSN 275
Query 397 DEDNQPLAGLVPGKSF 412
+ G+ P
Sbjct 276 GD-----TGIAPSNYL 286
>sp|B4JTT7|HTRA2_DROGR Serine protease HTRA2, mitochondrial OS=Drosophila
grimshawi OX=7222 GN=HtrA2 PE=3 SV=1
Length=426
Score = 38.9 bits (89), Expect = 0.15, Method: Composition-based stats.
Identities = 19/60 (32%), Positives = 30/60 (50%), Gaps = 3/60 (5%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 335
V++ +++ G A SG L GD V IN EI+ +V+D L+D L V++
Sbjct 357 HGVLVWKVIVGSPAH-SGGLQPGDIVTHINKKEIKNSS--DVYDALADGKKDLDMVILRG 413
>sp|A1DEZ0|SHO1_NEOFI High osmolarity signaling protein sho1 OS=Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65
/ FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117
GN=sho1 PE=3 SV=1
Length=288
Score = 38.5 bits (88), Expect = 0.15, Method: Composition-based stats.
Identities = 19/76 (25%), Positives = 27/76 (36%), Gaps = 16/76 (21%)
Query 337 QIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREG 396
Q P K I+ +D +P D + SF K +IL V WWQA +
Sbjct 226 QPTEYPYKAKAIY---SYDANPEDANEI-------SFSKHEILEVSDVS-GRWWQARK-- 272
Query 397 DEDNQPLAGLVPGKSF 412
+ G+ P
Sbjct 273 ---SNGETGIAPSNYL 285
>sp|Q3UTJ2|SRBS2_MOUSE Sorbin and SH3 domain-containing protein
2 OS=Mus musculus OX=10090 GN=Sorbs2 PE=1 SV=2
Length=1180
Score = 39.3 bits (90), Expect = 0.15, Method: Composition-based stats.
Identities = 17/82 (21%), Positives = 37/82 (45%), Gaps = 7/82 (9%)
Query 325 HGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ 384
TLT + + + + ++ + KA +D+ LSF+KGD ++++ +
Sbjct 923 SSTLTDLGRSASRERRGTPEKEKLPAKAVYDFKAQTSKE-------LSFKKGDTVYILRK 975
Query 385 EDPNWWQAYREGDEDNQPLAGL 406
D NW++ G P++ +
Sbjct 976 IDQNWYEGEHHGRVGIFPISYV 997
>sp|C4JLG3|SHO1_UNCRE High osmolarity signaling protein SHO1 OS=Uncinocarpus
reesii (strain UAMH 1704) OX=336963 GN=SHO1 PE=3
SV=1
Length=283
Score = 38.5 bits (88), Expect = 0.15, Method: Composition-based stats.
Identities = 16/62 (26%), Positives = 23/62 (37%), Gaps = 11/62 (18%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
KA + Y+ + D +SF K +IL V WWQA + G+ P
Sbjct 230 KAIYAYEANPDDA-----NEISFTKNEILEVSDVS-GRWWQAKK-----ATGETGIAPSN 278
Query 411 SF 412
Sbjct 279 YL 280
>sp|Q2S9Q5|AROK_HAHCH Shikimate kinase OS=Hahella chejuensis (strain
KCTC 2396) OX=349521 GN=aroK PE=3 SV=1
Length=192
Score = 37.7 bits (86), Expect = 0.15, Method: Composition-based stats.
Identities = 10/48 (21%), Positives = 24/48 (50%), Gaps = 0/48 (0%)
Query 463 ILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASA 510
+L Y +S++ K+ ++L+GP G+ + + L + + F +
Sbjct 1 MLRYRGVSIWTVRVKAKKNVVLVGPMGTGKTTIGKLLAKELQFEFVDS 48
>sp|Q5ZLR6|ARHG6_CHICK Rho guanine nucleotide exchange factor
6 OS=Gallus gallus OX=9031 GN=ARHGEF6 PE=2 SV=1
Length=764
Score = 39.3 bits (90), Expect = 0.15, Method: Composition-based stats.
Identities = 22/95 (23%), Positives = 35/95 (37%), Gaps = 15/95 (16%)
Query 322 SDMHGTLTFVLIPSQQIKPPPAKETV--IHVKAHFDYDPSDDPYVPCRELGLSFQKGDIL 379
S G T + Q + + VKA F++ ++ E LS KGDI+
Sbjct 127 SAAGGAHTDSNSTASQSAKEMTENGSHQLVVKARFNFKQTN-------EDELSVNKGDII 179
Query 380 HVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ 414
+V E+ WW+ G G P ++
Sbjct 180 YVTRVEEGGWWEGTLNGKT------GWFPSNYVRE 208
>sp|Q3SZ01|SH3Y1_BOVIN SH3 domain-containing YSC84-like protein
1 OS=Bos taurus OX=9913 GN=SH3YL1 PE=2 SV=1
Length=341
Score = 38.5 bits (88), Expect = 0.15, Method: Composition-based stats.
Identities = 20/110 (18%), Positives = 36/110 (33%), Gaps = 21/110 (19%)
Query 311 GKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV------IHVKAHFDYDPSDDPYV 364
+ + G+ + + + +E V I V A + ++
Sbjct 242 SSRPEQSSAQVQLSSGSQSSRNEYNLYPELSSYRERVGNSNQPIEVTALYSFEGQQPGD- 300
Query 365 PCRELGLSFQKGDILHVISQED--PNWWQAYREGDEDNQPLAGLVPGKSF 412
L+FQ GD + VIS+ D +WW+ G G+ P
Sbjct 301 ------LNFQAGDRITVISKTDSHFDWWEGKLRG------RTGIFPANYV 338
>sp|A8MT19|RHN2P_HUMAN Putative rhophilin-2-like protein RHPN2P1
OS=Homo sapiens OX=9606 GN=RHPN2P1 PE=5 SV=2
Length=583
Score = 38.9 bits (89), Expect = 0.15, Method: Composition-based stats.
Identities = 35/213 (16%), Positives = 69/213 (32%), Gaps = 22/213 (10%)
Query 125 EDLFSSLK-HIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMN--KASPPFP 181
E S L H+ L + ++ + + A H + K
Sbjct 294 EKCLSQLYDHMPEGLTPLATLKN-DQQRRQLGKSHLHRAMAHHEESVREASLCKKLRSIE 352
Query 182 LISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQEMQLEPITDER 241
++ AQE ++ L H+E +L L++ P V + Q
Sbjct 353 VLQKVLCAAQE-RSRLTYAQHQEDDDLLNLIHAP----------SVVAKTEQEPKGPLSV 401
Query 242 VYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEV 301
+ + + A + LG T+R V + + +A +G GD +
Sbjct 402 FLANKQWMPPRSNRFT----AEEGDLGFTLRGN-APVEVHFLDPYCSALVAGA-RGGDYI 455
Query 302 LEINGIEIRGKDVNEVFDLLSDMHG-TLTFVLI 333
+ I ++ + V+EV LL + ++
Sbjct 456 VSIQLVDCKWLTVSEVMKLLKSFGEDEIEMKVV 488
>sp|Q4KGQ4|DEGPL_PSEF5 Probable periplasmic serine endoprotease
DegP-like OS=Pseudomonas fluorescens (strain ATCC BAA-477
/ NRRL B-23932 / Pf-5) OX=220664 GN=mucD PE=3 SV=1
Length=476
Score = 38.9 bits (89), Expect = 0.15, Method: Composition-based stats.
Identities = 13/48 (27%), Positives = 22/48 (46%), Gaps = 2/48 (4%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIE-IRGKDVNEVFDLLSD 323
++++I G A K G L GD +L +NG + D+ + L
Sbjct 296 GALVAQIQDDGPAAK-GGLQVGDVILSLNGQPIVMSADLPHLVGALKA 342
>sp|O43586|PPIP1_HUMAN Proline-serine-threonine phosphatase-interacting
protein 1 OS=Homo sapiens OX=9606 GN=PSTPIP1 PE=1
SV=1
Length=416
Score = 38.9 bits (89), Expect = 0.15, Method: Composition-based stats.
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 14/84 (17%)
Query 331 VLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW 390
I Q+I+ PA + +A +DY + L GDIL VI + + WW
Sbjct 346 TAIAVQEIQGNPASPAQEY-RALYDYTAQNPDE-------LDLSAGDILEVILEGEDGWW 397
Query 391 QAYREGDEDNQPLAGLVPGKSFQQ 414
R G G VPG ++
Sbjct 398 TVERNG------QRGFVPGSYLEK 415
>sp|B8NEM4|SHO1_ASPFN High osmolarity signaling protein sho1 OS=Aspergillus
flavus (strain ATCC 200026 / FGSC A1120 / IAM
13836 / NRRL 3357 / JCM 12722 / SRRC 167) OX=332952 GN=sho1
PE=3 SV=1
Length=311
Score = 38.5 bits (88), Expect = 0.16, Method: Composition-based stats.
Identities = 18/76 (24%), Positives = 27/76 (36%), Gaps = 16/76 (21%)
Query 337 QIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREG 396
Q P + I+ +D +P D + SF K +IL V WWQA +
Sbjct 249 QPTEYPYRAKAIY---SYDANPEDANEI-------SFTKHEILEVSDVS-GRWWQARKSN 297
Query 397 DEDNQPLAGLVPGKSF 412
+ G+ P
Sbjct 298 GD-----TGIAPSNYL 308
>sp|A4VX53|DER_STRSY GTPase Der OS=Streptococcus suis (strain
05ZYH33) OX=391295 GN=der PE=3 SV=1
Length=436
Score = 38.9 bits (89), Expect = 0.16, Method: Composition-based stats.
Identities = 23/88 (26%), Positives = 36/88 (41%), Gaps = 14/88 (16%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ--AFEADIA 541
LIG N G++ L ++ +E+ AS V TTR D HF + F I
Sbjct 179 LIGRPNVGKSSLINAILGEER-VIASPVAGTTR-------DAIDTHFTDPEGQEF-TMID 229
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINS 569
+ G+ +N T SV + + +
Sbjct 230 TAGMRKSGKVYEN---TEKYSVMRAMRA 254
>sp|A4W3F7|DER_STRS2 GTPase Der OS=Streptococcus suis (strain
98HAH33) OX=391296 GN=der PE=3 SV=1
Length=436
Score = 38.9 bits (89), Expect = 0.16, Method: Composition-based stats.
Identities = 23/88 (26%), Positives = 36/88 (41%), Gaps = 14/88 (16%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ--AFEADIA 541
LIG N G++ L ++ +E+ AS V TTR D HF + F I
Sbjct 179 LIGRPNVGKSSLINAILGEER-VIASPVAGTTR-------DAIDTHFTDPEGQEF-TMID 229
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINS 569
+ G+ +N T SV + + +
Sbjct 230 TAGMRKSGKVYEN---TEKYSVMRAMRA 254
>sp|C3NEH0|KCY_SULIY Cytidylate kinase OS=Sulfolobus islandicus
(strain Y.G.57.14 / Yellowstone #1) OX=439386 GN=cmk PE=3
SV=1
Length=189
Score = 37.7 bits (86), Expect = 0.16, Method: Composition-based stats.
Identities = 29/201 (14%), Positives = 67/201 (33%), Gaps = 37/201 (18%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF--EA 538
II+ GP G+ + +L N+ +F SA + + + + V+ F +
Sbjct 2 IIIISGPPGSGKTSVAIKLANELSYKFISAGKIFRDIAQKMGLDIINLNKVAESNFDIDK 61
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+ F +++ K ++ + I++
Sbjct 62 MVDKKIF------------------EFILSE-KNLIIESHIAGWL---FREYTNIAIYLW 99
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTRE----------MEQNNGHYFDTAIV--NS 646
P + +A K + + +II++ ++ N+ FD I N
Sbjct 100 AP-LKIRANRIAIRDKISYDQAISQIIKREYMHYKRFNKFYGIDINDLSVFDLVINTSNV 158
Query 647 DLDKAYQELLRLINKLDTEPQ 667
D++ + +L ++ + PQ
Sbjct 159 DVNNIVKLILTYLSLVSQNPQ 179
>sp|C3NH82|KCY_SULIN Cytidylate kinase OS=Sulfolobus islandicus
(strain Y.N.15.51 / Yellowstone #2) OX=419942 GN=cmk PE=3
SV=1
Length=189
Score = 37.7 bits (86), Expect = 0.16, Method: Composition-based stats.
Identities = 29/201 (14%), Positives = 67/201 (33%), Gaps = 37/201 (18%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF--EA 538
II+ GP G+ + +L N+ +F SA + + + + V+ F +
Sbjct 2 IIIISGPPGSGKTSVAIKLANELSYKFISAGKIFRDIAQKMGLDIINLNKVAESNFDIDK 61
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIA 598
+ F +++ K ++ + I++
Sbjct 62 MVDKKIF------------------EFILSE-KNLIIESHIAGWL---FREYTNIAIYLW 99
Query 599 PPSQERLRALLAKEGKNPKPEELREIIEKTRE----------MEQNNGHYFDTAIV--NS 646
P + +A K + + +II++ ++ N+ FD I N
Sbjct 100 AP-LKIRANRIAIRDKISYDQAISQIIKREYMHYKRFNKFYGIDINDLSVFDLVINTSNV 158
Query 647 DLDKAYQELLRLINKLDTEPQ 667
D++ + +L ++ + PQ
Sbjct 159 DVNNIVKLILTYLSLVSQNPQ 179
>sp|A5D7F8|SH3R1_BOVIN E3 ubiquitin-protein ligase SH3RF1 OS=Bos
taurus OX=9913 GN=SH3RF1 PE=2 SV=1
Length=840
Score = 39.3 bits (90), Expect = 0.16, Method: Composition-based stats.
Identities = 27/158 (17%), Positives = 47/158 (30%), Gaps = 19/158 (12%)
Query 331 VLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW 390
++ P Q P KA +D++ D L F K D+L VI + D NW
Sbjct 190 IIKPLPQPPPQC--------KALYDFEVKDKEADKDC---LPFAKDDVLTVIRRVDENW- 237
Query 391 QAYREGDEDNQPLAGLVPGKSFQQQREAMKQ-TIEEDKEPEKSGKLWCAKKNKKKRKKVL 449
+ G+ P + A + ++ P +
Sbjct 238 -----AEGMLADKIGIFPISYVEFNSAAKQLIEWDQPPGPGVAAGEGALATTPSSTTTKQ 292
Query 450 YNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGP 487
+ KN + S Q A ++ + + P
Sbjct 293 PDGKKNTK-KRHSFTSLSMASKASQAAQQRHSMEISPP 329
>sp|A6LSK4|RSGA_CLOB8 Small ribosomal subunit biogenesis GTPase
RsgA OS=Clostridium beijerinckii (strain ATCC 51743 / NCIMB
8052) OX=290402 GN=rsgA PE=3 SV=1
Length=290
Score = 38.5 bits (88), Expect = 0.16, Method: Composition-based stats.
Identities = 9/30 (30%), Positives = 14/30 (47%), Gaps = 0/30 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKE 503
+ R + GP G++ L +L NKE
Sbjct 149 EEKIRGNITVFCGPSGAGKSTLINKLSNKE 178
>sp|Q8UII7|UGPC1_AGRFC sn-glycerol-3-phosphate import ATP-binding
protein UgpC 1 OS=Agrobacterium fabrum (strain C58 / ATCC
33970) OX=176299 GN=ugpC1 PE=3 SV=1
Length=366
Score = 38.5 bits (88), Expect = 0.16, Method: Composition-based stats.
Identities = 27/163 (17%), Positives = 50/163 (31%), Gaps = 40/163 (25%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
I+L+GP CG++ L + + E + T D+ V D + DI
Sbjct 33 IVLVGPSGCGKSTLLRMVAGLED------ISEGTVKIGDRVVNQTD-------PADRDI- 78
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSG----KICLLSLRTQSLKTLRNSDLKPYIIFI 597
+N SVR+ + G K + + + R L+PY+
Sbjct 79 -------AMVFQNYALYPHMSVRENLEYGLKNRKTAKTEIDARVAEAARMLQLEPYL--- 128
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFD 640
+ G+ + + + + FD
Sbjct 129 ------ERKPRALSGGQR------QRVAMGRAIVRKPAAFLFD 159
>sp|Q8FXK7|VIRBB_BRUSU Type IV secretion system protein VirB11
OS=Brucella suis biovar 1 (strain 1330) OX=204722 GN=virB11
PE=1 SV=1
Length=361
Score = 38.5 bits (88), Expect = 0.16, Method: Composition-based stats.
Identities = 15/84 (18%), Positives = 28/84 (33%), Gaps = 5/84 (6%)
Query 460 NEEILTYEE----MSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEK-DRFASAVPHT 514
+E+L +E MS + +R I++ G G+ L + LM + D+ +
Sbjct 152 EQELLALKEAGDYMSFLRRAVQLERVIVVAGETGSGKTTLMKALMQEIPFDQRLITIEDV 211
Query 515 TRSRRDQEVAGRDYHFVSRQAFEA 538
+ S E
Sbjct 212 PELFLPDHPNHVHLFYPSEAKEEE 235
>sp|P56945|BCAR1_HUMAN Breast cancer anti-estrogen resistance
protein 1 OS=Homo sapiens OX=9606 GN=BCAR1 PE=1 SV=2
Length=870
Score = 38.9 bits (89), Expect = 0.16, Method: Composition-based stats.
Identities = 16/45 (36%), Positives = 21/45 (47%), Gaps = 9/45 (20%)
Query 371 LSFQKGDILHVISQED---PNWWQAYREGDEDNQPLAGLVPGKSF 412
LSF+KGDI+ V+ Q+ WW G G+VPG
Sbjct 22 LSFRKGDIMTVLEQDTQGLDGWWLCSLHG------RQGIVPGNRL 60
>sp|Q9Z6T0|DEGPL_CHLPN Probable periplasmic serine endoprotease
DegP-like OS=Chlamydia pneumoniae OX=83558 GN=htrA PE=3 SV=1
Length=488
Score = 38.9 bits (89), Expect = 0.16, Method: Composition-based stats.
Identities = 18/102 (18%), Positives = 41/102 (40%), Gaps = 10/102 (10%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
++ +++ +VKG A+K+GL E D ++ NG E+ + L + + +
Sbjct 311 EKVYGALVTDVVKGSPADKAGLKQE-DVIIAYNGKEVDSLSMFRNAVSLMNPDTRIVLKV 369
Query 333 IPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQ 374
+ ++ P + P +D + +G+ Q
Sbjct 370 VREGKVIEIPVTVSQ---------APKEDGMSALQRVGIRVQ 402
>sp|A5GFW5|CASS4_PIG Cas scaffolding protein family member 4 OS=Sus
scrofa OX=9823 GN=CASS4 PE=3 SV=1
Length=784
Score = 38.9 bits (89), Expect = 0.16, Method: Composition-based stats.
Identities = 20/71 (28%), Positives = 27/71 (38%), Gaps = 16/71 (23%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDP---NWWQAYREGDEDNQPLAGLV 407
+A +D P L+F +GDIL ++ Q+ P WW G GL
Sbjct 17 RALYDNHPDCSDE-------LAFCRGDILTILEQDVPESEGWWTCLLHG------RQGLA 63
Query 408 PGKSFQQQREA 418
P Q EA
Sbjct 64 PANRLQILEEA 74
>sp|Q6FUM2|YFH7_CANGA ATP-dependent kinase YFH7 OS=Candida glabrata
(strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622
/ NRRL Y-65 / CBS 138) OX=284593 GN=YFH7 PE=3 SV=1
Length=345
Score = 38.5 bits (88), Expect = 0.16, Method: Composition-based stats.
Identities = 20/106 (19%), Positives = 43/106 (41%), Gaps = 16/106 (15%)
Query 467 EEMSLYHQPA---NRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV 523
EE+ ++ N + + ++GP G++ + ++L KD ++ + + +
Sbjct 9 EEVIASYREICKENYRLLVFIVGPPGSGKSTIAEKL----KDAINTSYLDYLKEIDRKTL 64
Query 524 AGRDYHFVSRQAFEADIAAGKFIEHG---EFEKNLYGTSIDSVRQV 566
+Y+ ++ F I G+ I E +N DSV V
Sbjct 65 RCENYNHINIDQFVQGIE-GETISSALEDERHENF-----DSVENV 104
>sp|B2V4B8|RSGA_CLOBA Small ribosomal subunit biogenesis GTPase
RsgA OS=Clostridium botulinum (strain Alaska E43 / Type E3)
OX=508767 GN=rsgA PE=3 SV=1
Length=290
Score = 38.5 bits (88), Expect = 0.17, Method: Composition-based stats.
Identities = 25/115 (22%), Positives = 41/115 (36%), Gaps = 22/115 (19%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKE-------KDRFASAVPHTTRSRRDQEV-AG--RDY 528
+L GP G++ L +L +KE ++ HTTR EV G D
Sbjct 154 GNITVLCGPSGAGKSTLINKLTDKEHMLTGIVSEKIGRGK-HTTRHSELIEVSNGYIVDT 212
Query 529 HFVSRQAFEADIAAGK----FIEHGEFEKN--LYGT-----SIDSVRQVINSGKI 572
S + + + F E E ++ G +++Q + GKI
Sbjct 213 PGFSTLEIKELMEKEELKYCFPEFEEHNESCKYRGCLHNKEPKCAIKQDVEDGKI 267
>sp|Q8YDY9|VIRBB_BRUME Type IV secretion system protein VirB11
OS=Brucella melitensis biotype 1 (strain 16M / ATCC 23456 /
NCTC 10094) OX=224914 GN=virB11 PE=3 SV=2
Length=362
Score = 38.5 bits (88), Expect = 0.17, Method: Composition-based stats.
Identities = 15/84 (18%), Positives = 28/84 (33%), Gaps = 5/84 (6%)
Query 460 NEEILTYEE----MSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEK-DRFASAVPHT 514
+E+L +E MS + +R I++ G G+ L + LM + D+ +
Sbjct 152 EQELLALKEAGDYMSFLRRAVQLERVIVVAGETGSGKTTLMKALMQEIPFDQRLITIEDV 211
Query 515 TRSRRDQEVAGRDYHFVSRQAFEA 538
+ S E
Sbjct 212 PELFLPDHPNHVHLFYPSEAKEEE 235
>sp|P0C534|VIRBB_BRUAB Type IV secretion system protein VirB11
OS=Brucella abortus biovar 1 (strain 9-941) OX=262698 GN=virB11
PE=3 SV=1
Length=362
Score = 38.5 bits (88), Expect = 0.17, Method: Composition-based stats.
Identities = 15/84 (18%), Positives = 28/84 (33%), Gaps = 5/84 (6%)
Query 460 NEEILTYEE----MSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEK-DRFASAVPHT 514
+E+L +E MS + +R I++ G G+ L + LM + D+ +
Sbjct 152 EQELLALKEAGDYMSFLRRAVQLERVIVVAGETGSGKTTLMKALMQEIPFDQRLITIEDV 211
Query 515 TRSRRDQEVAGRDYHFVSRQAFEA 538
+ S E
Sbjct 212 PELFLPDHPNHVHLFYPSEAKEEE 235
>sp|Q2YJ82|VIRBB_BRUA2 Type IV secretion system protein VirB11
OS=Brucella abortus (strain 2308) OX=359391 GN=virB11 PE=3
SV=1
Length=362
Score = 38.5 bits (88), Expect = 0.17, Method: Composition-based stats.
Identities = 15/84 (18%), Positives = 28/84 (33%), Gaps = 5/84 (6%)
Query 460 NEEILTYEE----MSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEK-DRFASAVPHT 514
+E+L +E MS + +R I++ G G+ L + LM + D+ +
Sbjct 152 EQELLALKEAGDYMSFLRRAVQLERVIVVAGETGSGKTTLMKALMQEIPFDQRLITIEDV 211
Query 515 TRSRRDQEVAGRDYHFVSRQAFEA 538
+ S E
Sbjct 212 PELFLPDHPNHVHLFYPSEAKEEE 235
>sp|A5GJ48|MTNC_SYNPW Enolase-phosphatase E1 OS=Synechococcus
sp. (strain WH7803) OX=32051 GN=mtnC PE=3 SV=1
Length=242
Score = 38.1 bits (87), Expect = 0.17, Method: Composition-based stats.
Identities = 11/51 (22%), Positives = 23/51 (45%), Gaps = 3/51 (6%)
Query 615 NPKPEELREIIEKTREMEQNNG---HYFDTAIVNSDLDKAYQELLRLINKL 662
+P+ + ++ + + + + HYFD I N A +EL +I +
Sbjct 58 DPESKSQALLLRASNQNQPTSEDIIHYFDHLIQNDRKSTALKELQGIIWEQ 108
>sp|B9DTQ3|DER_STRU0 GTPase Der OS=Streptococcus uberis (strain
ATCC BAA-854 / 0140J) OX=218495 GN=der PE=3 SV=1
Length=436
Score = 38.9 bits (89), Expect = 0.17, Method: Composition-based stats.
Identities = 26/98 (27%), Positives = 40/98 (41%), Gaps = 15/98 (15%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE-ADIAA 542
LIG N G++ L ++ +E+ AS V TTR D HF + E I
Sbjct 179 LIGRPNVGKSSLINAILGEER-VIASPVAGTTR-------DAIDTHFTDQDGQEYNMIDT 230
Query 543 GKFIEHGEFEKNLYGTSIDSV---RQVINSGKICLLSL 577
+ G+ +N T SV + I+ + LL +
Sbjct 231 AGMRKSGKVYEN---TEKYSVMRAMRAIDRSDVVLLVI 265
>sp|B5ZSN8|ATPG_RHILW ATP synthase gamma chain OS=Rhizobium leguminosarum
bv. trifolii (strain WSM2304) OX=395492 GN=atpG
PE=3 SV=1
Length=294
Score = 38.5 bits (88), Expect = 0.17, Method: Composition-based stats.
Identities = 21/115 (18%), Positives = 39/115 (34%), Gaps = 22/115 (19%)
Query 560 IDSVRQVINSGKIC-LLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKE-GKNPK 617
D VR+++ GK + ++ + LR ER K G
Sbjct 103 RDHVRKLVAEGKTVKIFTVGKKGYDILRREYASLI--------IERKELRDVKRIGFENA 154
Query 618 PEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPST 672
+ + II+ E + F Y E +I+++ T Q +P++
Sbjct 155 DQIGKRIIDMYAAGEFDVCTLF------------YSEFKSVISQIPTAQQLIPAS 197
>sp|Q325N3|TAUB_SHIBS Taurine import ATP-binding protein TauB
OS=Shigella boydii serotype 4 (strain Sb227) OX=300268 GN=tauB
PE=3 SV=1
Length=255
Score = 38.1 bits (87), Expect = 0.17, Method: Composition-based stats.
Identities = 15/124 (12%), Positives = 36/124 (29%), Gaps = 18/124 (15%)
Query 464 LTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV 523
E+++L ++++GP CG+ L + + S R
Sbjct 15 PALEDINL---TLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSIQLAGKRIEGPGAE 71
Query 524 AGRDYHFVSRQAFEADIAAGKFIEHGEFEKNL-YGTSIDSVR--QVINSGKICLLSLRTQ 580
G F+ + + N+ +G + + Q + L + +
Sbjct 72 RGV--------VFQ----NEGLLPWRNVQDNVAFGLQLAGIEKMQRLEIAHQVLKKVGLE 119
Query 581 SLKT 584
+
Sbjct 120 GAEK 123
>sp|A1URR2|UGPC_BARBK sn-glycerol-3-phosphate import ATP-binding
protein UgpC OS=Bartonella bacilliformis (strain ATCC 35685
/ KC583 / Herrer 020/F12,63) OX=360095 GN=ugpC PE=3 SV=1
Length=345
Score = 38.5 bits (88), Expect = 0.17, Method: Composition-based stats.
Identities = 17/109 (16%), Positives = 33/109 (30%), Gaps = 26/109 (24%)
Query 482 IILIGPQNCGQNELRQRL--MNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
++++GP CG++ L + + + K +R + A
Sbjct 33 LVIVGPSGCGKSTLLRIIAGLEKVTSGELYIDNELINNREPADRD------------IAM 80
Query 540 IAAG-KFIEHGEFEKNL-YG-----TSIDSVRQVINSGKIC--LLSLRT 579
+ H NL YG T + + + I LL +
Sbjct 81 VFQNYALYPHMTVRGNLEYGLKNRKTPKEDINKRIA---HVAKLLEIEP 126
>sp|C5FH98|SHO1_ARTOC High osmolarity signaling protein SHO1 OS=Arthroderma
otae (strain ATCC MYA-4605 / CBS 113480) OX=554155
GN=SHO1 PE=3 SV=1
Length=284
Score = 38.1 bits (87), Expect = 0.17, Method: Composition-based stats.
Identities = 16/62 (26%), Positives = 24/62 (39%), Gaps = 11/62 (18%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
KA + Y+ + D +SF K +IL V WWQA + + G+ P
Sbjct 231 KAIYSYEANPDDA-----NEISFTKHEILEVSDVS-GRWWQAKK-----STGETGIAPSN 279
Query 411 SF 412
Sbjct 280 YL 281
>sp|Q9BVN2|RUSC1_HUMAN AP-4 complex accessory subunit RUSC1 OS=Homo
sapiens OX=9606 GN=RUSC1 PE=1 SV=3
Length=902
Score = 38.9 bits (89), Expect = 0.17, Method: Composition-based stats.
Identities = 31/151 (21%), Positives = 50/151 (33%), Gaps = 22/151 (15%)
Query 260 EKARDIPLGATVRNEMDSVIISRI--VKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEV 317
E A++ PL + + R+ V GG AE +
Sbjct 764 EGAQERPLPTDEMAPGRGLWLGRLFGVPGGPAENENGALKSRRPSSW-------LPPTVS 816
Query 318 FDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGD 377
L + P +T V+A D+ + LSF++G+
Sbjct 817 VLALVKRGAPPEMPSPQELEASAPRMVQTHRAVRALCDHTAARPDQ-------LSFRRGE 869
Query 378 ILHVISQEDPNWWQAYREGDEDNQPLAGLVP 408
+L VI+ D +W R G + + GLVP
Sbjct 870 VLRVITTVDEDW---LRCGRDGME---GLVP 894
>sp|D4DA58|SHO1_TRIVH High osmolarity signaling protein SHO1 OS=Trichophyton
verrucosum (strain HKI 0517) OX=663202 GN=SHO1
PE=3 SV=1
Length=285
Score = 38.1 bits (87), Expect = 0.18, Method: Composition-based stats.
Identities = 16/62 (26%), Positives = 24/62 (39%), Gaps = 11/62 (18%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
KA + Y+ + D +SF K +IL V WWQA + + G+ P
Sbjct 232 KAIYSYEANPDDA-----NEISFTKHEILEVSDVS-GRWWQAKK-----STGETGIAPSN 280
Query 411 SF 412
Sbjct 281 YL 282
>sp|D4ARB8|SHO1_ARTBC High osmolarity signaling protein SHO1 OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371)
OX=663331 GN=SHO1 PE=3 SV=1
Length=285
Score = 38.1 bits (87), Expect = 0.18, Method: Composition-based stats.
Identities = 16/62 (26%), Positives = 24/62 (39%), Gaps = 11/62 (18%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
KA + Y+ + D +SF K +IL V WWQA + + G+ P
Sbjct 232 KAIYSYEANPDDA-----NEISFTKHEILEVSDVS-GRWWQAKK-----STGETGIAPSN 280
Query 411 SF 412
Sbjct 281 YL 282
>sp|Q5JCS6|SI1L2_RAT Signal-induced proliferation-associated 1-like
protein 2 OS=Rattus norvegicus OX=10116 GN=Sipa1l2 PE=1
SV=1
Length=1722
Score = 38.9 bits (89), Expect = 0.18, Method: Composition-based stats.
Identities = 27/151 (18%), Positives = 55/151 (36%), Gaps = 11/151 (7%)
Query 240 ERVYESIGQYGGETVKIVRIEKARDIPLG------ATVRNEMDSVIISRIVKGGAAEKSG 293
+ E I + V + R + ++ L + + ++ + G A K+G
Sbjct 927 DNSSEDIREIVQRLVIVTRGCETVEMTLRRNGLGQLGFHVNFEGI-VADVEPFGFAWKAG 985
Query 294 LLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAH 353
L +G ++EI + + ++ DLL T+ V+I + P + +
Sbjct 986 -LRQGSRLVEICKVAVATLTHEQMIDLLR-TSVTVKVVIIQPHEDGSPRRGCSELCRIPM 1043
Query 354 FDYDPSDDPYVPCRELGLSFQKGDILHVISQ 384
+Y D PC E F++ H +
Sbjct 1044 VEY-KLDSEGTPC-EYKTPFRRNTTWHRVPT 1072
>sp|Q57242|UUP_HAEIN ATP-binding protein Uup OS=Haemophilus influenzae
(strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421
GN=uup PE=3 SV=1
Length=647
Score = 38.9 bits (89), Expect = 0.18, Method: Composition-based stats.
Identities = 30/206 (15%), Positives = 63/206 (31%), Gaps = 50/206 (24%)
Query 410 KSFQQQREAMKQ--TIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKN-DDYDNEEILTY 466
K Q+ ++Q + + L ++ +++R+ V+ A D + +
Sbjct 261 KRLAQEEVWIRQGIKARRTRNEGRVRALKVMREERRQRRDVMGTAKLQLDTSSRSGKIVF 320
Query 467 EEMSLYHQPANRKRP------------IILIGPQNCGQNELRQRLMNKEKDRFASAVPHT 514
E + ++ A + I L+GP CG+ + L+ + + T
Sbjct 321 EMEDVSYEIAGKTLLKDFSTTILRGDKIALVGPNGCGKTTFIKLLLGE--------IQPT 372
Query 515 TRSRRDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICL 574
+ R Y + AD+ +V + GK
Sbjct 373 SGKIRCGTKLEIAYF----DQYRADLD-----------------PEKTVMDNVADGKQ-- 409
Query 575 LSLRTQSLKTLRNSDLKPYIIFIAPP 600
+ +K L+ F+ PP
Sbjct 410 -DIEINGVKRHVLGYLQD---FLFPP 431
>sp|Q9HKZ2|CDC61_THEAC Putative ORC1-type DNA replication protein
1 OS=Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728
/ JCM 9062 / NBRC 15155 / AMRC-C165) OX=273075 GN=cdc6-1
PE=3 SV=1
Length=347
Score = 38.5 bits (88), Expect = 0.18, Method: Composition-based stats.
Identities = 19/116 (16%), Positives = 39/116 (34%), Gaps = 18/116 (16%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
+IL G G+ + L + R + V Y +V +
Sbjct 26 LILYGDSGTGKTVTMRYLARE------------IRDPQVVYVNAIAYRYVKNVLIDFLSK 73
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVI-NSGKICLLSLRTQSLKTLRNSDLKPYIIF 596
G + E++ Y + + ++ N GK +L + ++ L+ Y +F
Sbjct 74 FGIIV----PERSSYASLFTRIEGLLRNQGKNVILVID-EAANILKGDYDGLYYLF 124
>sp|Q2SZW0|MSBA_BURTA ATP-dependent lipid A-core flippase OS=Burkholderia
thailandensis (strain ATCC 700388 / DSM 13276 /
CCUG 48851 / CIP 106301 / E264) OX=271848 GN=msbA PE=3 SV=1
Length=596
Score = 38.9 bits (89), Expect = 0.18, Method: Composition-based stats.
Identities = 25/174 (14%), Positives = 53/174 (30%), Gaps = 26/174 (15%)
Query 408 PGKSFQQQREAMKQTIEEDK------EPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNE 461
P K + +++ + + + + + + + + + +
Sbjct 308 PLKHLMDVNQPLQRGMTAAELIFGLIDEPREPEGGGKPLARASGAIEFSHVSFSYGISRD 367
Query 462 EILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQ 521
T +++S P + L GP G+ L L RF T R
Sbjct 368 GRQTLDDVSFTVAP---GEMVALAGPSGSGKTTLVNLL-----PRFFDPSSGTVR----- 414
Query 522 EVAGR---DYHFVSRQAFEADIAAGKFIEHGEFEKNL-YG-TS-IDSVRQVINS 569
V G +Y + A ++ + + N+ YG T D V + +
Sbjct 415 -VDGVALPEYSLHDLRNQIAMVSQDVVLFNDTIAANVAYGQTPERDGVEAALRA 467
>sp|P40996|SCD2_SCHPO Protein scd2/ral3 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=scd2 PE=4 SV=1
Length=536
Score = 38.9 bits (89), Expect = 0.18, Method: Composition-based stats.
Identities = 21/86 (24%), Positives = 42/86 (49%), Gaps = 14/86 (16%)
Query 350 VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG 409
++A +DY + +SF KGD HVI +E+ +A+ E G VP
Sbjct 29 IRALYDYTAR-------KATEVSFAKGDFFHVIGREND---KAWYEVCNPAAGTRGFVPV 78
Query 410 KSFQQQREAMKQTIEEDKEPEKSGKL 435
F++ + +T++ +++ + SG++
Sbjct 79 SHFEE----IGKTVKSERDSDGSGQI 100
>sp|A5DAL3|NM111_PICGU Pro-apoptotic serine protease NMA111 OS=Meyerozyma
guilliermondii (strain ATCC 6260 / CBS 566 / DSM
6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) OX=294746 GN=NMA111
PE=3 SV=2
Length=991
Score = 38.9 bits (89), Expect = 0.18, Method: Composition-based stats.
Identities = 17/65 (26%), Positives = 33/65 (51%), Gaps = 6/65 (9%)
Query 274 EMDSVIISR-IVKGGAAEKSGLLHEGDEVLEINGIEIRG-KDVNEVFDLLSDMHGTLTFV 331
+ ++++ ++ G A+ G L EGD ++ ING I V+E+ D + +L FV
Sbjct 314 DKIGLLVAELVLPEGPAD--GKLKEGDTLISINGTPIASFISVDEILD--EQVGQSLKFV 369
Query 332 LIPSQ 336
+ +
Sbjct 370 IQRNG 374
>sp|Q6D734|FBPC1_PECAS Fe(3+) ions import ATP-binding protein
FbpC 1 OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC
BAA-672) OX=218491 GN=fbpC1 PE=3 SV=1
Length=352
Score = 38.5 bits (88), Expect = 0.19, Method: Composition-based stats.
Identities = 16/105 (15%), Positives = 37/105 (35%), Gaps = 8/105 (8%)
Query 478 RKRPIILIGPQNCGQNELRQRLMN-KEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ + + L+GP CG+ + + + ++ + + R + F S F
Sbjct 35 QGKMVTLLGPSGCGKTTVLRAVAGLEKPTEGQIFIDGEDVTERSIQQRDICMVFQSYALF 94
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS 581
+ G+ I +G + G + Q + K L + +
Sbjct 95 PHM-SLGENIGYGL---KMLGRPKAEINQRV---KEALALVDLEG 132
>sp|B6EM43|AROK_ALISL Shikimate kinase OS=Aliivibrio salmonicida
(strain LFI1238) OX=316275 GN=aroK PE=3 SV=1
Length=172
Score = 37.3 bits (85), Expect = 0.19, Method: Composition-based stats.
Identities = 28/194 (14%), Positives = 53/194 (27%), Gaps = 32/194 (16%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQ-------EVAGRDYHFV 531
KR I L+GP G++ + + L + T R +V G + +
Sbjct 4 KRNIFLVGPMGAGKSTIGRHLAQQ--LHMEFLDSDTVIEERTGADIAWVFDVEGEEGFRI 61
Query 532 SRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLK 591
+ D+ + I + S +S ++ G + L + K L +
Sbjct 62 REEGVINDLTQEQGIVLATGGGS--VISKESRNRLSARGVVVYLETTIE--KQLARTQ-- 115
Query 592 PYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKA 651
K E + +E D + D A
Sbjct 116 ----------------RDKKRPLLQTDEPREVLEALAKERNALYEEVSDYVVRTDD-QSA 158
Query 652 YQELLRLINKLDTE 665
++I L+
Sbjct 159 KVVANQIIQMLEER 172
>sp|C0M7M5|KTHY_STRE4 Thymidylate kinase OS=Streptococcus equi
subsp. equi (strain 4047) OX=553482 GN=tmk PE=3 SV=1
Length=211
Score = 37.7 bits (86), Expect = 0.19, Method: Composition-based stats.
Identities = 16/112 (14%), Positives = 39/112 (35%), Gaps = 12/112 (11%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R + I GP G+ + +RL+ + + TTR +A + + +
Sbjct 3 RGKLITFEGPDGAGKTTVLERLVPLLQAALGQTI-VTTREPGGVAIAEKIRQLILDVSHT 61
Query 538 ADIAAGKFIEH-GEFEKNLYGTSIDSVRQVINSGKICLLS--LR----TQSL 582
+ + + ++L ++ + + SG + L+ + Q
Sbjct 62 TMDDKTELLLYIAARRQHL----VEKIMPALESGHLVLVDRFIDSSVAYQGA 109
>sp|Q8YCB1|UGPC_BRUME sn-glycerol-3-phosphate import ATP-binding
protein UgpC OS=Brucella melitensis biotype 1 (strain 16M
/ ATCC 23456 / NCTC 10094) OX=224914 GN=ugpC PE=3 SV=1
Length=351
Score = 38.5 bits (88), Expect = 0.19, Method: Composition-based stats.
Identities = 19/104 (18%), Positives = 38/104 (37%), Gaps = 18/104 (17%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++L+GP CG++ L + + E ++ T S ++ V + + A +
Sbjct 33 VVLVGPSGCGKSTLLRMIAGLE------SITSGTISIGERVVNNVE----PAERDIAMVF 82
Query 542 AG-KFIEHGEFEKNL-YG-----TSIDSVRQVINSGKICLLSLR 578
H +NL YG T + + + I L +
Sbjct 83 QNYALYPHMTVRENLAYGLKNRKTPKEEIERRIAKAAKV-LEIE 125
>sp|Q5XXR3|ARHG6_RAT Rho guanine nucleotide exchange factor 6
OS=Rattus norvegicus OX=10116 GN=Arhgef6 PE=1 SV=1
Length=772
Score = 38.9 bits (89), Expect = 0.19, Method: Composition-based stats.
Identities = 22/92 (24%), Positives = 38/92 (41%), Gaps = 18/92 (20%)
Query 334 PSQQIKPPPAK-----ETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPN 388
P QQ + A+ + VKA F++ ++ E LS KGDI++V E+
Sbjct 144 PEQQSEEKAAEMTENGSHQLIVKARFNFKQTN-------EDELSVCKGDIIYVTRVEEGG 196
Query 389 WWQAYREGDEDNQPLAGLVPGKSFQQQREAMK 420
WW+ G G P ++ + + +
Sbjct 197 WWEGTLNG------RTGWFPSNYVREIKPSER 222
>sp|P04821|CDC25_YEAST Cell division control protein 25 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=CDC25 PE=1 SV=1
Length=1589
Score = 38.9 bits (89), Expect = 0.20, Method: Composition-based stats.
Identities = 13/70 (19%), Positives = 28/70 (40%), Gaps = 4/70 (6%)
Query 353 HFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSF 412
F+Y D LS Q+G+ ++++++ WW D + + G P
Sbjct 68 DFNYPIKKD----SSSQLLSVQQGETIYILNKNSSGWWDGLVIDDSNGKVNRGWFPQNFG 123
Query 413 QQQREAMKQT 422
+ R++ +
Sbjct 124 RPLRDSHLRK 133
>sp|Q9CHH6|DER_LACLA GTPase Der OS=Lactococcus lactis subsp. lactis
(strain IL1403) OX=272623 GN=der PE=3 SV=1
Length=436
Score = 38.5 bits (88), Expect = 0.20, Method: Composition-based stats.
Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 17/99 (17%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ--AFEADIA 541
LIG N G++ L ++ +++ AS + TTR D HFV + F I
Sbjct 179 LIGRPNVGKSSLINAILGEDR-VIASPIAGTTR-------DAIDTHFVDSEDQEFV-MID 229
Query 542 AGKFIEHGEFEKNLYGTSIDSV---RQVINSGKICLLSL 577
+ G+ +N T SV + I+ I L+ +
Sbjct 230 TAGMRKSGKIYEN---TEKYSVMRAMRAIDRSDIVLMVI 265
>sp|O55033|NCK2_MOUSE Cytoplasmic protein NCK2 OS=Mus musculus
OX=10090 GN=Nck2 PE=1 SV=1
Length=380
Score = 38.5 bits (88), Expect = 0.20, Method: Composition-based stats.
Identities = 16/48 (33%), Positives = 23/48 (48%), Gaps = 7/48 (15%)
Query 368 ELGLSFQKGDILHVISQ--EDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
E LSF+KG+ + VI + DP WW+ + + GLVP
Sbjct 211 EEELSFEKGETMEVIEKPENDPEWWKCK-----NARGQVGLVPKNYVV 253
>sp|Q82TL6|POTA_NITEU Spermidine/putrescine import ATP-binding
protein PotA OS=Nitrosomonas europaea (strain ATCC 19718 /
CIP 103999 / KCTC 2705 / NBRC 14298) OX=228410 GN=potA PE=3
SV=1
Length=361
Score = 38.5 bits (88), Expect = 0.20, Method: Composition-based stats.
Identities = 11/62 (18%), Positives = 17/62 (27%), Gaps = 1/62 (2%)
Query 479 KRPIILIGPQNCGQNELRQRLMN-KEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
L+GP CG+ L + + D + + E F S F
Sbjct 29 GELFTLLGPSGCGKTTLLRMIAGFDVPDSGQILLDGQDIANTPPEKRPIHTVFQSYALFP 88
Query 538 AD 539
Sbjct 89 HM 90
>sp|B0KV30|DEGPL_PSEPG Probable periplasmic serine endoprotease
DegP-like OS=Pseudomonas putida (strain GB-1) OX=76869 GN=PputGB1_4377
PE=3 SV=1
Length=477
Score = 38.5 bits (88), Expect = 0.20, Method: Composition-based stats.
Identities = 21/95 (22%), Positives = 38/95 (40%), Gaps = 12/95 (13%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIE-IRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+++++++ G A K G L GD +L +NG + D+ + L D +I +
Sbjct 297 GALVAQVLENGPAAK-GGLQVGDVILSMNGQPIVMSADLPHLVGGLKD-GEKAKLEIIRN 354
Query 336 QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELG 370
+ + I V A P DD + G
Sbjct 355 GK-----RQNLDISVGAL----PDDDADIGTGAEG 380
>sp|Q923K4|GTPB3_MOUSE tRNA modification GTPase GTPBP3, mitochondrial
OS=Mus musculus OX=10090 GN=Gtpbp3 PE=2 SV=1
Length=492
Score = 38.5 bits (88), Expect = 0.20, Method: Composition-based stats.
Identities = 26/129 (20%), Positives = 44/129 (34%), Gaps = 17/129 (13%)
Query 412 FQQQREAMKQTIEE-DKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNE--------E 462
+ +Q + + D E + + W K Y DD E E
Sbjct 166 RAETEAQRRQALRQLDGELSQLCQGWAKTLTKALAYVEAYIDFGEDDNLEEGVLEQADRE 225
Query 463 ILTYEEMSLYHQPANRK--RP-----IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTT 515
+ E H R+ R +++ GP N G++ L L++++ S P TT
Sbjct 226 VRALEVALGSHLRDARRGQRLLSGANVVVTGPPNAGKSSLVN-LLSQKPVSIVSPEPGTT 284
Query 516 RSRRDQEVA 524
R + V
Sbjct 285 RDVLETPVD 293
>sp|Q3BTW0|DER_XANC5 GTPase Der OS=Xanthomonas campestris pv.
vesicatoria (strain 85-10) OX=316273 GN=der PE=3 SV=1
Length=465
Score = 38.5 bits (88), Expect = 0.20, Method: Composition-based stats.
Identities = 37/205 (18%), Positives = 73/205 (36%), Gaps = 49/205 (24%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRS--RRDQEVAGRDYHFVSRQAFEAD 539
I +G N G++ L RL+ +E+ AS VP TTR D E GR Y +
Sbjct 181 IAFVGRPNVGKSTLVNRLLGEER-MIASEVPGTTRDSIAVDLERDGRQYRLIDTAGLRRR 239
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQ------------------------VINSGKICLL 575
+ +E K ++ ++ Q ++++G+ ++
Sbjct 240 GKVEEAVEKFSAFK-----TLQAIEQCQVAVLMLDATEGVTDQDATILGAILDAGRALVV 294
Query 576 SLR-TQSLKTLRNSDLKPYII----FIAPPSQERLRAL--LAKEGKNPKPEELREIIEKT 628
++ + + + + F+ + + L G +RE+ +
Sbjct 295 AINKWDGQSDYQRAQAEDLLSRKLGFV---NWAEAVRISALHGSG-------MRELFQAI 344
Query 629 REMEQNNGHYFDTAIVNSDLDKAYQ 653
+ H F T+ VN L+ AY+
Sbjct 345 HRAHASATHEFSTSEVNQALEIAYE 369
>sp|Q8PKY6|DER_XANAC GTPase Der OS=Xanthomonas axonopodis pv.
citri (strain 306) OX=190486 GN=der PE=3 SV=1
Length=465
Score = 38.5 bits (88), Expect = 0.20, Method: Composition-based stats.
Identities = 37/205 (18%), Positives = 73/205 (36%), Gaps = 49/205 (24%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRS--RRDQEVAGRDYHFVSRQAFEAD 539
I +G N G++ L RL+ +E+ AS VP TTR D E GR Y +
Sbjct 181 IAFVGRPNVGKSTLVNRLLGEER-MIASEVPGTTRDSIAVDLERDGRQYRLIDTAGLRRR 239
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQ------------------------VINSGKICLL 575
+ +E K ++ ++ Q ++++G+ ++
Sbjct 240 GKVEEAVEKFSAFK-----TLQAIEQCQVAVLMLDATEGVTDQDATILGAILDAGRALVV 294
Query 576 SLR-TQSLKTLRNSDLKPYII----FIAPPSQERLRAL--LAKEGKNPKPEELREIIEKT 628
++ + + + + F+ + + L G +RE+ +
Sbjct 295 AINKWDGQSDYQRAQAEDLLSRKLGFV---NWAEAVRISALHGSG-------MRELFQAI 344
Query 629 REMEQNNGHYFDTAIVNSDLDKAYQ 653
+ H F T+ VN L+ AY+
Sbjct 345 HRAHASATHEFSTSEVNQALEIAYE 369
>sp|O15259|NPHP1_HUMAN Nephrocystin-1 OS=Homo sapiens OX=9606
GN=NPHP1 PE=1 SV=1
Length=732
Score = 38.5 bits (88), Expect = 0.21, Method: Composition-based stats.
Identities = 16/39 (41%), Positives = 23/39 (59%), Gaps = 1/39 (3%)
Query 371 LSFQKGDILHVISQEDPNWWQAY-REGDEDNQPLAGLVP 408
L+F+KG+IL VI ++ WW A +G+E P L P
Sbjct 171 LTFKKGEILLVIEKKPDGWWIAKDAKGNEGLVPRTYLEP 209
>sp|Q925Q9|SH3K1_RAT SH3 domain-containing kinase-binding protein
1 OS=Rattus norvegicus OX=10116 GN=Sh3kbp1 PE=1 SV=2
Length=709
Score = 38.5 bits (88), Expect = 0.21, Method: Composition-based stats.
Identities = 12/53 (23%), Positives = 23/53 (43%), Gaps = 6/53 (11%)
Query 362 PYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ 414
Y+P + L + GDI+ V+ + + WW+ G G+ P ++
Sbjct 108 SYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKT------GMFPSNFIKE 154
Score = 38.1 bits (87), Expect = 0.34, Method: Composition-based stats.
Identities = 20/78 (26%), Positives = 34/78 (44%), Gaps = 13/78 (17%)
Query 354 FDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
FDY D L+ G+++ I +ED WW+ G GL P +
Sbjct 8 FDYQAQHDDE-------LTISVGEVITNIRKEDGGWWEGQING------RRGLFPDNFVR 54
Query 414 QQREAMKQTIEEDKEPEK 431
+ ++ +K+ + +K PEK
Sbjct 55 EIKKDVKKDLLSNKAPEK 72
Score = 35.0 bits (79), Expect = 2.5, Method: Composition-based stats.
Identities = 17/78 (22%), Positives = 32/78 (41%), Gaps = 11/78 (14%)
Query 336 QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE--DPNWWQAY 393
+ + +T + K F Y+ +D + +E GDI+ +I+++ D WW+
Sbjct 302 SKTEMDSRTKTKDYCKVIFPYEAQNDDELTIKE-------GDIVTLINKDCIDVGWWEGE 354
Query 394 REGDEDNQPLA--GLVPG 409
G P L+P
Sbjct 355 LNGRRGVFPDNFVKLLPS 372
>sp|Q8R550|SH3K1_MOUSE SH3 domain-containing kinase-binding protein
1 OS=Mus musculus OX=10090 GN=Sh3kbp1 PE=1 SV=1
Length=709
Score = 38.5 bits (88), Expect = 0.21, Method: Composition-based stats.
Identities = 12/53 (23%), Positives = 23/53 (43%), Gaps = 6/53 (11%)
Query 362 PYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ 414
Y+P + L + GDI+ V+ + + WW+ G G+ P ++
Sbjct 108 SYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKT------GMFPSNFIKE 154
Score = 38.1 bits (87), Expect = 0.32, Method: Composition-based stats.
Identities = 21/78 (27%), Positives = 34/78 (44%), Gaps = 13/78 (17%)
Query 354 FDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
FDY D L+ G+++ I +ED WW+ G GL P +
Sbjct 8 FDYQAQHDDE-------LTISVGEVITNIRKEDGGWWEGQING------RRGLFPDNFVR 54
Query 414 QQREAMKQTIEEDKEPEK 431
+ ++ MK+ + +K PEK
Sbjct 55 EIKKDMKKDLLSNKAPEK 72
Score = 35.0 bits (79), Expect = 2.5, Method: Composition-based stats.
Identities = 17/78 (22%), Positives = 32/78 (41%), Gaps = 11/78 (14%)
Query 336 QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE--DPNWWQAY 393
+ + +T + K F Y+ +D + +E GDI+ +I+++ D WW+
Sbjct 302 SKTEMDSRTKTKDYCKVIFPYEAQNDDELTIKE-------GDIVTLINKDCIDVGWWEGE 354
Query 394 REGDEDNQPLA--GLVPG 409
G P L+P
Sbjct 355 LNGRRGVFPDNFVKLLPS 372
>sp|Q16584|M3K11_HUMAN Mitogen-activated protein kinase kinase
kinase 11 OS=Homo sapiens OX=9606 GN=MAP3K11 PE=1 SV=1
Length=847
Score = 38.9 bits (89), Expect = 0.21, Method: Composition-based stats.
Identities = 18/67 (27%), Positives = 27/67 (40%), Gaps = 18/67 (27%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE-----DPNWWQAYREGDEDNQPLAG 405
A FDY+PS + L+ +KGD + V+S++ D WW G G
Sbjct 47 TALFDYEPS-------GQDELALRKGDRVEVLSRDAAISGDEGWWAGQVGG------QVG 93
Query 406 LVPGKSF 412
+ P
Sbjct 94 IFPSNYV 100
>sp|Q920G0|SKAP2_RAT Src kinase-associated phosphoprotein 2 OS=Rattus
norvegicus OX=10116 GN=Skap2 PE=1 SV=1
Length=358
Score = 38.1 bits (87), Expect = 0.21, Method: Composition-based stats.
Identities = 14/46 (30%), Positives = 24/46 (52%), Gaps = 8/46 (17%)
Query 371 LSFQKGDILHVISQEDP--NWWQAYREGDEDNQPLAGLVPGKSFQQ 414
LSF++GD+++++S+E WW +G GLVP +
Sbjct 315 LSFKRGDVIYILSKEYNRYGWWVGEMQG------AIGLVPKAYLME 354
>sp|Q5RDX5|NGEF_PONAB Ephexin-1 OS=Pongo abelii OX=9601 GN=NGEF
PE=2 SV=1
Length=709
Score = 38.5 bits (88), Expect = 0.21, Method: Composition-based stats.
Identities = 23/146 (16%), Positives = 43/146 (29%), Gaps = 12/146 (8%)
Query 309 IRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVI--HVKAHFDYDPSD--DPYV 364
+ D E +L + + S P + T D PYV
Sbjct 568 LENADDREATYMLKASSQSEMKRWMTS----LAPNRRTKFVSFTSRLLDCPQVQCVHPYV 623
Query 365 PCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIE 424
+ L+ + DIL+++ + D W R D G P ++ ++
Sbjct 624 AQQPDELTLELADILNILDKTDDGWIFGERLHD----QERGWFPSSMTEEILNPKIRSQN 679
Query 425 EDKEPEKSGKLWCAKKNKKKRKKVLY 450
+ + K R+K+
Sbjct 680 LKECFRVHKMDDPQRSQNKDRRKLGS 705
>sp|Q7MGA2|RSGA2_VIBVY Small ribosomal subunit biogenesis GTPase
RsgA 2 OS=Vibrio vulnificus (strain YJ016) OX=196600 GN=rsgA2
PE=3 SV=1
Length=353
Score = 38.1 bits (87), Expect = 0.21, Method: Composition-based stats.
Identities = 14/69 (20%), Positives = 24/69 (35%), Gaps = 11/69 (16%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ R + IG G++ L L+ +E + T R+ + GR +
Sbjct 190 KGRTVAFIGSSGVGKSTLTNTLLGEETQQ--------TGGIREDDSKGRH---TTTARSV 238
Query 538 ADIAAGKFI 546
I G I
Sbjct 239 HMIPDGALI 247
>sp|A5W8F5|DEGPL_PSEP1 Probable periplasmic serine endoprotease
DegP-like OS=Pseudomonas putida (strain ATCC 700007 / DSM
6899 / BCRC 17059 / F1) OX=351746 GN=Pput_4291 PE=3 SV=1
Length=477
Score = 38.5 bits (88), Expect = 0.21, Method: Composition-based stats.
Identities = 19/82 (23%), Positives = 35/82 (43%), Gaps = 8/82 (10%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIE-IRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+++++++ G A K G L GD +L +NG + D+ + L D +I +
Sbjct 297 GALVAQVLENGPAAK-GGLQVGDVILSMNGQPIVMSADLPHLVGGLKD-GEKAKLEIIRN 354
Query 336 QQIKPPPAKETVIHVKAHFDYD 357
+ + I V A D D
Sbjct 355 GK-----RQNLDISVGALPDDD 371
>sp|Q9D236|HTRA3_MOUSE Serine protease HTRA3 OS=Mus musculus OX=10090
GN=Htra3 PE=1 SV=3
Length=459
Score = 38.5 bits (88), Expect = 0.21, Method: Composition-based stats.
Identities = 15/68 (22%), Positives = 30/68 (44%), Gaps = 9/68 (13%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD------VNEVFDLLSDMHGT-- 327
+ + +V +++ G + +GD ++++NG + +NE LL G
Sbjct 390 SGIYVQEVVPNSPSQR-GGIQDGDIIVKVNGRPLADSSELQEAVLNESSLLLEVRRGNDD 448
Query 328 LTFVLIPS 335
L F +IP
Sbjct 449 LLFSIIPE 456
>sp|Q7MFH3|Y4347_VIBVY Putative ABC transporter ATP-binding protein
VVA0347 OS=Vibrio vulnificus (strain YJ016) OX=196600
GN=VVA0347 PE=3 SV=1
Length=574
Score = 38.5 bits (88), Expect = 0.21, Method: Composition-based stats.
Identities = 13/61 (21%), Positives = 26/61 (43%), Gaps = 3/61 (5%)
Query 452 ANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAV 511
+N + Y++ + T ++L + + I++IGP G++ L Q L V
Sbjct 6 SNFSFRYESLDKPTLRNINLRIEKGEK---IVIIGPSGSGKSTLGQCLNGLIPHAIKGEV 62
Query 512 P 512
Sbjct 63 S 63
>sp|Q8P979|DER_XANCP GTPase Der OS=Xanthomonas campestris pv.
campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568
/ P 25) OX=190485 GN=der PE=3 SV=1
Length=465
Score = 38.5 bits (88), Expect = 0.21, Method: Composition-based stats.
Identities = 37/205 (18%), Positives = 73/205 (36%), Gaps = 49/205 (24%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRS--RRDQEVAGRDYHFVSRQAFEAD 539
I +G N G++ L RL+ +E+ AS VP TTR D E GR Y +
Sbjct 181 IAFVGRPNVGKSTLVNRLLGEER-MIASEVPGTTRDSIAVDLERDGRQYRLIDTAGLRRR 239
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQ------------------------VINSGKICLL 575
+ +E K ++ ++ Q ++++G+ ++
Sbjct 240 GKVEEAVEKFSAFK-----TLQAIEQCQVAVLMLDATEGVTDQDATILGAILDAGRALVV 294
Query 576 SLR-TQSLKTLRNSDLKPYII----FIAPPSQERLRAL--LAKEGKNPKPEELREIIEKT 628
++ + + + + F+ + + L G +RE+ +
Sbjct 295 AINKWDGQSDYQRAQAEDLLSRKLGFV---NWAEAVRISALHGSG-------MRELFQAI 344
Query 629 REMEQNNGHYFDTAIVNSDLDKAYQ 653
+ H F T+ VN L+ AY+
Sbjct 345 HRAHASATHEFSTSEVNQALEIAYE 369
>sp|B0RT56|DER_XANCB GTPase Der OS=Xanthomonas campestris pv.
campestris (strain B100) OX=509169 GN=der PE=3 SV=1
Length=465
Score = 38.5 bits (88), Expect = 0.21, Method: Composition-based stats.
Identities = 37/205 (18%), Positives = 73/205 (36%), Gaps = 49/205 (24%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRS--RRDQEVAGRDYHFVSRQAFEAD 539
I +G N G++ L RL+ +E+ AS VP TTR D E GR Y +
Sbjct 181 IAFVGRPNVGKSTLVNRLLGEER-MIASEVPGTTRDSIAVDLERDGRQYRLIDTAGLRRR 239
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQ------------------------VINSGKICLL 575
+ +E K ++ ++ Q ++++G+ ++
Sbjct 240 GKVEEAVEKFSAFK-----TLQAIEQCQVAVLMLDATEGVTDQDATILGAILDAGRALVV 294
Query 576 SLR-TQSLKTLRNSDLKPYII----FIAPPSQERLRAL--LAKEGKNPKPEELREIIEKT 628
++ + + + + F+ + + L G +RE+ +
Sbjct 295 AINKWDGQSDYQRAQAEDLLSRKLGFV---NWAEAVRISALHGSG-------MRELFQAI 344
Query 629 REMEQNNGHYFDTAIVNSDLDKAYQ 653
+ H F T+ VN L+ AY+
Sbjct 345 HRAHASATHEFSTSEVNQALEIAYE 369
>sp|Q4UUM0|DER_XANC8 GTPase Der OS=Xanthomonas campestris pv.
campestris (strain 8004) OX=314565 GN=der PE=3 SV=1
Length=465
Score = 38.5 bits (88), Expect = 0.21, Method: Composition-based stats.
Identities = 37/205 (18%), Positives = 73/205 (36%), Gaps = 49/205 (24%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRS--RRDQEVAGRDYHFVSRQAFEAD 539
I +G N G++ L RL+ +E+ AS VP TTR D E GR Y +
Sbjct 181 IAFVGRPNVGKSTLVNRLLGEER-MIASEVPGTTRDSIAVDLERDGRQYRLIDTAGLRRR 239
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQ------------------------VINSGKICLL 575
+ +E K ++ ++ Q ++++G+ ++
Sbjct 240 GKVEEAVEKFSAFK-----TLQAIEQCQVAVLMLDATEGVTDQDATILGAILDAGRALVV 294
Query 576 SLR-TQSLKTLRNSDLKPYII----FIAPPSQERLRAL--LAKEGKNPKPEELREIIEKT 628
++ + + + + F+ + + L G +RE+ +
Sbjct 295 AINKWDGQSDYQRAQAEDLLSRKLGFV---NWAEAVRISALHGSG-------MRELFQAI 344
Query 629 REMEQNNGHYFDTAIVNSDLDKAYQ 653
+ H F T+ VN L+ AY+
Sbjct 345 HRAHASATHEFSTSEVNQALEIAYE 369
>sp|Q8D3Z9|Y5533_VIBVU Putative ABC transporter ATP-binding protein
VV2_1533 OS=Vibrio vulnificus (strain CMCP6) OX=216895
GN=VV2_1533 PE=3 SV=2
Length=574
Score = 38.5 bits (88), Expect = 0.21, Method: Composition-based stats.
Identities = 13/61 (21%), Positives = 26/61 (43%), Gaps = 3/61 (5%)
Query 452 ANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAV 511
+N + Y++ + T ++L + + I++IGP G++ L Q L V
Sbjct 6 SNFSFRYESLDKPTLRNINLRIEKGEK---IVIIGPSGSGKSTLGQCLNGLIPHAIKGEV 62
Query 512 P 512
Sbjct 63 S 63
>sp|A6H603|NWD1_MOUSE NACHT domain- and WD repeat-containing protein
1 OS=Mus musculus OX=10090 GN=Nwd1 PE=2 SV=2
Length=1563
Score = 38.9 bits (89), Expect = 0.21, Method: Composition-based stats.
Identities = 25/145 (17%), Positives = 51/145 (35%), Gaps = 12/145 (8%)
Query 371 LSFQKGDILHVIS---QEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDK 427
LS KG IL + W ++ L K +Q A +T +
Sbjct 225 LSGLKGRILDAQPGALKSHHLSWSRDLVNPKNKAHARYL---KQLSEQFVA--RTNHQVL 279
Query 428 EPEKSGKLWCAKKN--KKKRKKVLYNANKNDDY--DNEEILTYEEMSLYHQPANRKRPII 483
E + +L + ++ + L+ + ++ ++E+L L + P++
Sbjct 280 EQLRELELARQELGWLYQEIRHHLWQSTESTKVFCGHQELLAQLRQQLRQDESRTHTPLV 339
Query 484 LIGPQNCGQNELRQRLMNKEKDRFA 508
L GP G+ L +L + +
Sbjct 340 LFGPPGIGKTSLMCKLAQQVPELLG 364
>sp|C0MGT8|KTHY_STRS7 Thymidylate kinase OS=Streptococcus equi
subsp. zooepidemicus (strain H70) OX=553483 GN=tmk PE=3 SV=1
Length=211
Score = 37.7 bits (86), Expect = 0.21, Method: Composition-based stats.
Identities = 15/112 (13%), Positives = 39/112 (35%), Gaps = 12/112 (11%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
R + I GP G+ + +RL+ + + TTR +A + + +
Sbjct 3 RGKLITFEGPDGAGKTTVLERLVPLLQAALGQTI-VTTREPGGVAIAEKIRQLILDVSHT 61
Query 538 ADIAAGKFIEH-GEFEKNLYGTSIDSVRQVINSGKICLLS--LR----TQSL 582
+ + + ++L ++ + + +G + L+ + Q
Sbjct 62 TMDDKTELLLYIAARRQHL----VEKIMPALEAGHLVLVDRFIDSSVAYQGA 109
>sp|Q8DYB3|KTHY_STRA5 Thymidylate kinase OS=Streptococcus agalactiae
serotype V (strain ATCC BAA-611 / 2603 V/R) OX=208435
GN=tmk PE=3 SV=1
Length=211
Score = 37.7 bits (86), Expect = 0.21, Method: Composition-based stats.
Identities = 14/100 (14%), Positives = 37/100 (37%), Gaps = 6/100 (6%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ I GP G+ + + ++ +++ + + TTR ++ H +
Sbjct 3 KGLMISFEGPDGAGKTTVLEAVLPLLREKLSQDIL-TTREPGGVTISEEIRHIILDVKHT 61
Query 538 ADIAAGKFIEH-GEFEKNLYGTSIDSVRQVINSGKICLLS 576
+ + + ++L ++ V + GKI L+
Sbjct 62 QMDKKTELLLYMAARRQHL----VEKVLPALEEGKIVLMD 97
>sp|Q8E3X8|KTHY_STRA3 Thymidylate kinase OS=Streptococcus agalactiae
serotype III (strain NEM316) OX=211110 GN=tmk PE=3 SV=1
Length=211
Score = 37.7 bits (86), Expect = 0.21, Method: Composition-based stats.
Identities = 14/100 (14%), Positives = 37/100 (37%), Gaps = 6/100 (6%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ I GP G+ + + ++ +++ + + TTR ++ H +
Sbjct 3 KGLMISFEGPDGAGKTTVLEAVLPLLREKLSQDIL-TTREPGGVTISEEIRHIILDVKHT 61
Query 538 ADIAAGKFIEH-GEFEKNLYGTSIDSVRQVINSGKICLLS 576
+ + + ++L ++ V + GKI L+
Sbjct 62 QMDKKTELLLYMAARRQHL----VEKVLPALEEGKIVLMD 97
>sp|Q3JZV8|KTHY_STRA1 Thymidylate kinase OS=Streptococcus agalactiae
serotype Ia (strain ATCC 27591 / A909 / CDC SS700) OX=205921
GN=tmk PE=3 SV=1
Length=211
Score = 37.7 bits (86), Expect = 0.21, Method: Composition-based stats.
Identities = 14/100 (14%), Positives = 37/100 (37%), Gaps = 6/100 (6%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ I GP G+ + + ++ +++ + + TTR ++ H +
Sbjct 3 KGLMISFEGPDGAGKTTVLEAVLPLLREKLSQDIL-TTREPGGVTISEEIRHIILDVKHT 61
Query 538 ADIAAGKFIEH-GEFEKNLYGTSIDSVRQVINSGKICLLS 576
+ + + ++L ++ V + GKI L+
Sbjct 62 QMDKKTELLLYMAARRQHL----VEKVLPALEEGKIVLMD 97
>sp|Q9NGP5|ABCG2_DICDI ABC transporter G family member 2 OS=Dictyostelium
discoideum OX=44689 GN=abcG2 PE=1 SV=2
Length=1328
Score = 38.9 bits (89), Expect = 0.22, Method: Composition-based stats.
Identities = 19/102 (19%), Positives = 41/102 (40%), Gaps = 11/102 (11%)
Query 407 VPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKN------DDYDN 460
+P + F Q+ A TI + S A K KK +Y +N +
Sbjct 11 IPLQEFGQKSFAADNTIGGMQS--ISYDNSGAPMGLYKEKKGMYVTARNLSMSIGTEKKG 68
Query 461 EEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNK 502
++ +++ + +P ++++G CG+ + + L N+
Sbjct 69 DKRNILSDLNFFLKP---GSMVLILGSPGCGKTSVMKALANQ 107
Score = 37.3 bits (85), Expect = 0.56, Method: Composition-based stats.
Identities = 14/58 (24%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query 446 KKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKE 503
K ++Y + D N+ + E++ Y +P + L+GP G++ L L N++
Sbjct 718 KDLVYEVDVKKDGKNQRLRLLNEINGYVKP---GMLLALMGPSGAGKSTLLDVLANRK 772
>sp|D0ZY51|DEGS_SALT1 Serine endoprotease DegS OS=Salmonella typhimurium
(strain 14028s / SGSC 2262) OX=588858 GN=degS PE=3
SV=1
Length=356
Score = 38.1 bits (87), Expect = 0.22, Method: Composition-based stats.
Identities = 8/74 (11%), Positives = 31/74 (42%), Gaps = 6/74 (8%)
Query 269 ATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK--DVNEVFDLLSDMHG 326
+ + + ++++ + G A +G + D ++ +N +++V ++ G
Sbjct 274 GSGMDPIQGIVVNEVTPNGPAALAG-IQVNDLIISVNNKPAVSALETMDQVAEI---RPG 329
Query 327 TLTFVLIPSQQIKP 340
++ V++ +
Sbjct 330 SVIPVVVMRDDKQL 343
>sp|Q9UMS6|SYNP2_HUMAN Synaptopodin-2 OS=Homo sapiens OX=9606
GN=SYNPO2 PE=1 SV=2
Length=1093
Score = 38.5 bits (88), Expect = 0.22, Method: Composition-based stats.
Identities = 17/67 (25%), Positives = 29/67 (43%), Gaps = 1/67 (1%)
Query 271 VRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTF 330
+ + + +++I A SG L EGDEV+ ING EV L+ + +L
Sbjct 24 GKEQKQPLQVAKIRNQSKASGSG-LCEGDEVVSINGNPCADLTYPEVIKLMESITDSLQM 82
Query 331 VLIPSQQ 337
++
Sbjct 83 LIKRPSS 89
>sp|A8Z454|DER_STAAT GTPase Der OS=Staphylococcus aureus (strain
USA300 / TCH1516) OX=451516 GN=der PE=3 SV=1
Length=436
Score = 38.5 bits (88), Expect = 0.22, Method: Composition-based stats.
Identities = 20/97 (21%), Positives = 35/97 (36%), Gaps = 12/97 (12%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
+IG N G++ L ++ +++ S V TTR + G+DY +
Sbjct 180 IIGRPNVGKSSLVNAILGEDR-VIVSNVAGTTRDAIDTEYSYDGQDYVLIDTA---GMRK 235
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
GK E E Y + I + L+ +
Sbjct 236 KGKVYESTE----KYSVLRA--LKAIERSNVVLVVID 266
>sp|Q2FGW7|DER_STAA3 GTPase Der OS=Staphylococcus aureus (strain
USA300) OX=367830 GN=der PE=3 SV=1
Length=436
Score = 38.5 bits (88), Expect = 0.22, Method: Composition-based stats.
Identities = 20/97 (21%), Positives = 35/97 (36%), Gaps = 12/97 (12%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
+IG N G++ L ++ +++ S V TTR + G+DY +
Sbjct 180 IIGRPNVGKSSLVNAILGEDR-VIVSNVAGTTRDAIDTEYSYDGQDYVLIDTA---GMRK 235
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
GK E E Y + I + L+ +
Sbjct 236 KGKVYESTE----KYSVLRA--LKAIERSNVVLVVID 266
>sp|Q2I0E5|INTU_XENLA Protein inturned OS=Xenopus laevis OX=8355
GN=intu PE=2 SV=1
Length=951
Score = 38.5 bits (88), Expect = 0.22, Method: Composition-based stats.
Identities = 12/60 (20%), Positives = 29/60 (48%), Gaps = 3/60 (5%)
Query 273 NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL 332
+ + +++ + G A + G + GD ++ +N +E+ V + +LS + G + L
Sbjct 209 SNQEKLVVHGFIPGSPAIRCGQVLIGDTLVAVNDVEV---HVENIERVLSCIPGPMQLKL 265
>sp|Q48EU9|DEGPL_PSE14 Probable periplasmic serine endoprotease
DegP-like OS=Pseudomonas savastanoi pv. phaseolicola (strain
1448A / Race 6) OX=264730 GN=mucD PE=3 SV=1
Length=479
Score = 38.5 bits (88), Expect = 0.23, Method: Composition-based stats.
Identities = 16/68 (24%), Positives = 29/68 (43%), Gaps = 2/68 (3%)
Query 277 SVIISRIVKGGAAEKSGLLHEGDEVLEINGIE-IRGKDVNEVFDLLSDMHGTLTFVLIPS 335
+++++++ G A K G L GD +L NG I D+ + L D V+
Sbjct 299 GALVAQVLEDGPAAK-GGLQVGDVILSANGQPIIMSADLPHLIGNLKDGSKAELEVIRDG 357
Query 336 QQIKPPPA 343
++ K
Sbjct 358 KRQKLTVT 365
>sp|Q1KKZ1|SKAP2_TAKRU Src kinase-associated phosphoprotein 2
OS=Takifugu rubripes OX=31033 GN=skap2 PE=3 SV=1
Length=329
Score = 38.1 bits (87), Expect = 0.23, Method: Composition-based stats.
Identities = 17/86 (20%), Positives = 32/86 (37%), Gaps = 10/86 (12%)
Query 331 VLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQED--PN 388
+ P + PP + +Y + LSF++GD ++++S+E
Sbjct 248 KVEPVSKHPPPTPAVDKS--TDYANYYQGLWDCMGDLPDELSFKRGDAIYILSREYQTFG 305
Query 389 WWQAYREGDEDNQPLAGLVPGKSFQQ 414
WW + G G+VP +
Sbjct 306 WWVGEKNG------QIGIVPKDYLME 325
>sp|A8WSQ9|PATR1_CAEBR Protein PAT1 homolog 1 OS=Caenorhabditis
briggsae OX=6238 GN=patr-1 PE=3 SV=2
Length=864
Score = 38.5 bits (88), Expect = 0.23, Method: Composition-based stats.
Identities = 35/265 (13%), Positives = 87/265 (33%), Gaps = 53/265 (20%)
Query 52 RSAQLERIRQQQEDMRRRREEEGKKQELDLNSSMRLKKLAQIPPKTGIDNPMFDTEEGIV 111
R Q ER+R ++++ +R R+E R+ + + P+ + + +
Sbjct 550 REMQKERLRDREKERQRERQE-------------RIDRGEERKPRQTLTDKFATSLGLPS 596
Query 112 LESPHYAVKILEIEDLFSSLKHIQHTLVDSQSQEDISLLLQLVQNKDFQNAFKIHNAITV 171
S H +L+++ S+ + L D + + VQ K ++ A+ +
Sbjct 597 KSSTHNPRHVLDMKAQVDSVDNQAKKLSDEERK-------NAVQKKLRTMLLRLEGALVL 649
Query 172 HMNKASPPFPLISNAQDLAQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAEQE 231
M L+ + + L + E+E
Sbjct 650 LME-------------------AEELRRTSSSDKSQFKDLTSE--------------EKE 676
Query 232 MQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEK 291
++E T + E +G + +++ + L + +I+S ++ G K
Sbjct 677 QEVEKRTSLIIDEFMGDDLPKLMQMSKGRAVLTRTLKVVGPRDQARIILSLMIAAGLVSK 736
Query 292 SGLLHEGDEVLEINGIEIRGKDVNE 316
++L + ++ ++
Sbjct 737 KMYGEIVLDILPVVHQKVSNLHPDQ 761
>sp|X2JAU8|NWK_DROME Protein nervous wreck OS=Drosophila melanogaster
OX=7227 GN=nwk PE=1 SV=1
Length=1075
Score = 38.5 bits (88), Expect = 0.23, Method: Composition-based stats.
Identities = 20/105 (19%), Positives = 46/105 (44%), Gaps = 17/105 (16%)
Query 302 LEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDD 361
+ + ++ + ++ D + ++ ++ P +++ K V A +DYD +
Sbjct 621 ISFSSVDYTVDNEDQTVDSM-QSPDQVSVIMAPQKRV-----KSDVEWCIALYDYDAT-- 672
Query 362 PYVPCRELGLSFQKGDILHVISQE----DPNWWQAYREGDEDNQP 402
E L+F++GD + +I++ D WW+ +G N P
Sbjct 673 -----AEDELTFEEGDKIKIITKTAHGVDDGWWEGELDGKFGNFP 712
>sp|Q9WYN2|KITH_THEMA Thymidine kinase OS=Thermotoga maritima
(strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
OX=243274 GN=tdk PE=1 SV=1
Length=184
Score = 37.3 bits (85), Expect = 0.23, Method: Composition-based stats.
Identities = 17/110 (15%), Positives = 35/110 (32%), Gaps = 19/110 (17%)
Query 479 KRPIILIGPQNCGQNE----------LRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDY 528
+ ++ GP G+ L ++ + K + S T G +
Sbjct 3 GKLTVITGPMYSGKTTELLSFVEIYKLGKKKVAVFKPKIDSRYHSTMIVSHSG--NGVEA 60
Query 529 HFVSR-QAFEADIAA---GKFIEHGEFEKNLYGTSIDSVRQVINSGKICL 574
H + R + I G FI+ +F + V+ +++ G
Sbjct 61 HVIERPEEMRKYIEEDTRGVFIDEVQFFNPS---LFEVVKDLLDRGIDVF 107
>sp|Q9Z2H7|GIPC2_MOUSE PDZ domain-containing protein GIPC2 OS=Mus
musculus OX=10090 GN=Gipc2 PE=1 SV=1
Length=314
Score = 38.1 bits (87), Expect = 0.24, Method: Composition-based stats.
Identities = 21/67 (31%), Positives = 28/67 (42%), Gaps = 2/67 (3%)
Query 253 TVKIVRIEKARDIPLGATVRNEMDS-VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
T K V + K+ D LG T+ + I RI G + + GD + ING I G
Sbjct 114 TKKEVNVYKSED-SLGLTITDNGVGYAFIKRIKDGSTIDSVKTICVGDHIECINGENIVG 172
Query 312 KDVNEVF 318
EV
Sbjct 173 WRHFEVA 179
>sp|P45092|ARTP_HAEIN Arginine transport ATP-binding protein ArtP
OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121
/ KW20 / Rd) OX=71421 GN=artP PE=3 SV=1
Length=243
Score = 37.7 bits (86), Expect = 0.24, Method: Composition-based stats.
Identities = 7/25 (28%), Positives = 13/25 (52%), Gaps = 0/25 (0%)
Query 475 PANRKRPIILIGPQNCGQNELRQRL 499
A ++L+GP G++ L + L
Sbjct 24 EAEEGDTVVLLGPSGAGKSTLIRTL 48
>sp|Q96B97|SH3K1_HUMAN SH3 domain-containing kinase-binding protein
1 OS=Homo sapiens OX=9606 GN=SH3KBP1 PE=1 SV=2
Length=665
Score = 38.5 bits (88), Expect = 0.24, Method: Composition-based stats.
Identities = 12/53 (23%), Positives = 23/53 (43%), Gaps = 6/53 (11%)
Query 362 PYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQ 414
Y+P + L + GDI+ V+ + + WW+ G G+ P ++
Sbjct 108 SYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKT------GMFPSNFIKE 154
Score = 37.3 bits (85), Expect = 0.59, Method: Composition-based stats.
Identities = 22/78 (28%), Positives = 33/78 (42%), Gaps = 13/78 (17%)
Query 354 FDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
FDY D L+ G+I+ I +ED WW+ G GL P +
Sbjct 8 FDYQAQHDDE-------LTISVGEIITNIRKEDGGWWEGQING------RRGLFPDNFVR 54
Query 414 QQREAMKQTIEEDKEPEK 431
+ ++ MK+ +K PEK
Sbjct 55 EIKKEMKKDPLTNKAPEK 72
Score = 35.8 bits (81), Expect = 1.6, Method: Composition-based stats.
Identities = 17/86 (20%), Positives = 33/86 (38%), Gaps = 15/86 (17%)
Query 329 TFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQE--D 386
T S + + ++ + K F Y+ +D + +E GDI+ +I+++ D
Sbjct 251 TTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKE-------GDIVTLINKDCID 303
Query 387 PNWWQAYREGDEDNQPLAGLVPGKSF 412
WW+ G G+ P
Sbjct 304 VGWWEGELNG------RRGVFPDNFV 323
>sp|D4A702|SYNP2_RAT Synaptopodin-2 OS=Rattus norvegicus OX=10116
GN=Synpo2 PE=1 SV=2
Length=1262
Score = 38.5 bits (88), Expect = 0.24, Method: Composition-based stats.
Identities = 17/77 (22%), Positives = 28/77 (36%), Gaps = 1/77 (1%)
Query 271 VRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTF 330
+ E + +++I A SG L GDEV+ ING EV L+ + +L
Sbjct 24 GKEEKQPLQVAKIRSQSKASDSG-LCVGDEVVSINGNPCADLTYPEVIKLMESITDSLHL 82
Query 331 VLIPSQQIKPPPAKETV 347
++
Sbjct 83 LIKRPTSGTSEALDSET 99
>sp|Q9Y5K6|CD2AP_HUMAN CD2-associated protein OS=Homo sapiens
OX=9606 GN=CD2AP PE=1 SV=1
Length=639
Score = 38.5 bits (88), Expect = 0.24, Method: Composition-based stats.
Identities = 23/115 (20%), Positives = 45/115 (39%), Gaps = 16/115 (14%)
Query 298 GDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKET------VIHVK 351
GD E +++R + + + + L P Q +T + +
Sbjct 217 GDIFKE-GSVKLRTRTSSSETEEKKPEKPLILQSLGPKTQSVEITKTDTEGKIKAKEYCR 275
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ--EDPNWWQAYREGDEDNQPLA 404
F Y+ ++ E L+F++G+I+H+IS+ + WW+ G E P
Sbjct 276 TLFAYEGTN-------EDELTFKEGEIIHLISKETGEAGWWRGELNGKEGVFPDN 323
Score = 36.2 bits (82), Expect = 1.2, Method: Composition-based stats.
Identities = 18/83 (22%), Positives = 28/83 (34%), Gaps = 13/83 (16%)
Query 332 LIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQ 391
+ P Q K K K F+Y +P E L + GDI+ + + + WW
Sbjct 95 IQPHPQTKNIKKKTKKRQCKVLFEY-------IPQNEDELELKVGDIIDINEEVEEGWWS 147
Query 392 AYREGDEDNQPLAGLVPGKSFQQ 414
GL P ++
Sbjct 148 G------TLNNKLGLFPSNFVKE 164
>sp|Q03ZG6|KTHY_LEUMM Thymidylate kinase OS=Leuconostoc mesenteroides
subsp. mesenteroides (strain ATCC 8293 / DSM 20343 /
BCRC 11652 / CCM 1803 / JCM 6124 / NCDO 523 / NBRC 100496 /
NCIMB 8023 / NCTC 12954 / NRRL B-1118 / 37Y) OX=203120 GN=tmk
PE=3 SV=1
Length=213
Score = 37.3 bits (85), Expect = 0.24, Method: Composition-based stats.
Identities = 12/100 (12%), Positives = 39/100 (39%), Gaps = 6/100 (6%)
Query 479 KRPIILI--GPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+PI + GP+ G+ + + L+++ K + + TTR ++ + +
Sbjct 2 PKPIFISFEGPEGAGKTSVLEALISELKTKLGDDL-VTTREPGGNPISEAIRSILQPEED 60
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLS 576
+ + + + +++++ ++ KI +
Sbjct 61 NGMDKRTEALLYTAARRQH---LVENIKPALDQNKIVISD 97
>sp|Q2TYB1|NM111_ASPOR Pro-apoptotic serine protease nma111 OS=Aspergillus
oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=nma111
PE=3 SV=1
Length=1027
Score = 38.5 bits (88), Expect = 0.24, Method: Composition-based stats.
Identities = 20/116 (17%), Positives = 46/116 (40%), Gaps = 5/116 (4%)
Query 235 EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGL 294
EP+T + + + + + + + E ++ I+ G A+ G
Sbjct 278 EPVTRGTIQTQWILKPFDECRRLGLTPEWEATVRKAAPTETSMLVAEIILPEGPAD--GK 335
Query 295 LHEGDEVLEINGIEIRG-KDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIH 349
L EGD +L++NG + ++++ D S + T+ ++ Q + +H
Sbjct 336 LEEGDVLLQVNGELLTQFIRLDDILD--SSVGQTVRLLVQRGGQDVEIECQVGDLH 389
>sp|Q9URW6|YIE2_SCHPO SH3 domain-containing protein PJ696.02 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812
GN=SPAPJ696.02 PE=1 SV=1
Length=430
Score = 38.1 bits (87), Expect = 0.25, Method: Composition-based stats.
Identities = 18/86 (21%), Positives = 30/86 (35%), Gaps = 19/86 (22%)
Query 333 IPSQQIKPPP-AKETVI---HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ--ED 386
PS+ P P K+ + +A + + LSFQKGDI+ ++ +
Sbjct 355 KPSRPTAPKPKFKQDSLGPNQARAMYSFAGEQPGD-------LSFQKGDIIDIVERSGSH 407
Query 387 PNWWQAYREGDEDNQPLAGLVPGKSF 412
+WW G+ P
Sbjct 408 DDWWTGR------IGYREGIFPANYV 427
>sp|Q4L6I0|DER_STAHJ GTPase Der OS=Staphylococcus haemolyticus
(strain JCSC1435) OX=279808 GN=der PE=3 SV=1
Length=436
Score = 38.1 bits (87), Expect = 0.25, Method: Composition-based stats.
Identities = 20/97 (21%), Positives = 35/97 (36%), Gaps = 12/97 (12%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
+IG N G++ L ++ +++ S V TTR + G+DY +
Sbjct 180 IIGRPNVGKSSLVNAILGEDR-VIVSNVAGTTRDAVDTEYSYDGQDYVLIDTA---GMRK 235
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
GK E E Y + I + L+ +
Sbjct 236 KGKVYESTE----KYSVLRA--LKAIERSNVVLIVID 266
>sp|Q92C36|Y1355_LISIN Putative zinc metalloprotease Lin1355 OS=Listeria
innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)
OX=272626 GN=lin1355 PE=3 SV=1
Length=420
Score = 38.1 bits (87), Expect = 0.25, Method: Composition-based stats.
Identities = 19/60 (32%), Positives = 31/60 (52%), Gaps = 2/60 (3%)
Query 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 339
+ I+ GAA ++G L +GDEVL ING E + + V + + TL F + + +
Sbjct 205 LGNIMPDGAAAQAG-LEKGDEVLSINGKETKSWT-DIVQSVSENPGKTLDFKIDRDGKTQ 262
>sp|Q8I1A6|SH3G3_DROWI Endophilin-A OS=Drosophila willistoni OX=7260
GN=EndoA PE=3 SV=1
Length=366
Score = 38.1 bits (87), Expect = 0.25, Method: Composition-based stats.
Identities = 13/55 (24%), Positives = 27/55 (49%), Gaps = 7/55 (13%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGL 406
A +D+DP + L F++ DI+ ++++ D NW++ G P + +
Sbjct 312 ALYDFDPENPGE-------LGFKENDIITLLNRVDDNWYEGSVNGRTGYFPQSYV 359
>sp|Q8N5V2|NGEF_HUMAN Ephexin-1 OS=Homo sapiens OX=9606 GN=NGEF
PE=1 SV=2
Length=710
Score = 38.5 bits (88), Expect = 0.25, Method: Composition-based stats.
Identities = 23/146 (16%), Positives = 43/146 (29%), Gaps = 12/146 (8%)
Query 309 IRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVI--HVKAHFDYDPSD--DPYV 364
+ D E +L + + S P + T D PYV
Sbjct 569 LENADDREATYMLKASSQSEMKRWMTS----LAPNRRTKFVSFTSRLLDCPQVQCVHPYV 624
Query 365 PCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIE 424
+ L+ + DIL+++ + D W R D G P ++ ++
Sbjct 625 AQQPDELTLELADILNILDKTDDGWIFGERLHD----QERGWFPSSMTEEILNPKIRSQN 680
Query 425 EDKEPEKSGKLWCAKKNKKKRKKVLY 450
+ + K R+K+
Sbjct 681 LKECFRVHKMDDPQRSQNKDRRKLGS 706
>sp|O34375|MINJ_BACSU Cell division topological determinant MinJ
OS=Bacillus subtilis (strain 168) OX=224308 GN=minJ PE=1
SV=1
Length=397
Score = 38.1 bits (87), Expect = 0.25, Method: Composition-based stats.
Identities = 19/109 (17%), Positives = 40/109 (37%), Gaps = 18/109 (17%)
Query 269 ATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTL 328
+++ I+ AE L G+ + ++NGI ++ V++ ++ L +
Sbjct 297 FYFSKRDQGLMVLGIIPNTPAE-DLELKIGEIITKVNGIPVKN--VSDFYEALQHNRAYV 353
Query 329 TFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGD 377
+I E +A ++ + ELG+ F K D
Sbjct 354 KLEII-------GLNGEIRFDQRASYEGE--------HHELGILFVKDD 387
>sp|P64061|DER_STAAW GTPase Der OS=Staphylococcus aureus (strain
MW2) OX=196620 GN=der PE=3 SV=1
Length=436
Score = 38.1 bits (87), Expect = 0.25, Method: Composition-based stats.
Identities = 20/97 (21%), Positives = 35/97 (36%), Gaps = 12/97 (12%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
+IG N G++ L ++ +++ S V TTR + G+DY +
Sbjct 180 IIGRPNVGKSSLVNAILGEDR-VIVSNVAGTTRDAIDTEYSYDGQDYVLIDTA---GMRK 235
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
GK E E Y + I + L+ +
Sbjct 236 KGKVYESTE----KYSVLRA--LKAIERSNVVLVVID 266
>sp|Q6G988|DER_STAAS GTPase Der OS=Staphylococcus aureus (strain
MSSA476) OX=282459 GN=der PE=3 SV=1
Length=436
Score = 38.1 bits (87), Expect = 0.25, Method: Composition-based stats.
Identities = 20/97 (21%), Positives = 35/97 (36%), Gaps = 12/97 (12%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
+IG N G++ L ++ +++ S V TTR + G+DY +
Sbjct 180 IIGRPNVGKSSLVNAILGEDR-VIVSNVAGTTRDAIDTEYSYDGQDYVLIDTA---GMRK 235
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
GK E E Y + I + L+ +
Sbjct 236 KGKVYESTE----KYSVLRA--LKAIERSNVVLVVID 266
>sp|Q6GGT6|DER_STAAR GTPase Der OS=Staphylococcus aureus (strain
MRSA252) OX=282458 GN=der PE=3 SV=1
Length=436
Score = 38.1 bits (87), Expect = 0.25, Method: Composition-based stats.
Identities = 20/97 (21%), Positives = 35/97 (36%), Gaps = 12/97 (12%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
+IG N G++ L ++ +++ S V TTR + G+DY +
Sbjct 180 IIGRPNVGKSSLVNAILGEDR-VIVSNVAGTTRDAIDTEYSYDGQDYVLIDTA---GMRK 235
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
GK E E Y + I + L+ +
Sbjct 236 KGKVYESTE----KYSVLRA--LKAIERSNVVLVVID 266
>sp|P64060|DER_STAAN GTPase Der OS=Staphylococcus aureus (strain
N315) OX=158879 GN=der PE=1 SV=1
Length=436
Score = 38.1 bits (87), Expect = 0.25, Method: Composition-based stats.
Identities = 20/97 (21%), Positives = 35/97 (36%), Gaps = 12/97 (12%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
+IG N G++ L ++ +++ S V TTR + G+DY +
Sbjct 180 IIGRPNVGKSSLVNAILGEDR-VIVSNVAGTTRDAIDTEYSYDGQDYVLIDTA---GMRK 235
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
GK E E Y + I + L+ +
Sbjct 236 KGKVYESTE----KYSVLRA--LKAIERSNVVLVVID 266
>sp|P64059|DER_STAAM GTPase Der OS=Staphylococcus aureus (strain
Mu50 / ATCC 700699) OX=158878 GN=der PE=3 SV=1
Length=436
Score = 38.1 bits (87), Expect = 0.25, Method: Composition-based stats.
Identities = 20/97 (21%), Positives = 35/97 (36%), Gaps = 12/97 (12%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
+IG N G++ L ++ +++ S V TTR + G+DY +
Sbjct 180 IIGRPNVGKSSLVNAILGEDR-VIVSNVAGTTRDAIDTEYSYDGQDYVLIDTA---GMRK 235
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
GK E E Y + I + L+ +
Sbjct 236 KGKVYESTE----KYSVLRA--LKAIERSNVVLVVID 266
>sp|A6QH24|DER_STAAE GTPase Der OS=Staphylococcus aureus (strain
Newman) OX=426430 GN=der PE=3 SV=1
Length=436
Score = 38.1 bits (87), Expect = 0.25, Method: Composition-based stats.
Identities = 20/97 (21%), Positives = 35/97 (36%), Gaps = 12/97 (12%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
+IG N G++ L ++ +++ S V TTR + G+DY +
Sbjct 180 IIGRPNVGKSSLVNAILGEDR-VIVSNVAGTTRDAIDTEYSYDGQDYVLIDTA---GMRK 235
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
GK E E Y + I + L+ +
Sbjct 236 KGKVYESTE----KYSVLRA--LKAIERSNVVLVVID 266
>sp|Q5HFU8|DER_STAAC GTPase Der OS=Staphylococcus aureus (strain
COL) OX=93062 GN=der PE=3 SV=1
Length=436
Score = 38.1 bits (87), Expect = 0.25, Method: Composition-based stats.
Identities = 20/97 (21%), Positives = 35/97 (36%), Gaps = 12/97 (12%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
+IG N G++ L ++ +++ S V TTR + G+DY +
Sbjct 180 IIGRPNVGKSSLVNAILGEDR-VIVSNVAGTTRDAIDTEYSYDGQDYVLIDTA---GMRK 235
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
GK E E Y + I + L+ +
Sbjct 236 KGKVYESTE----KYSVLRA--LKAIERSNVVLVVID 266
>sp|A5IT03|DER_STAA9 GTPase Der OS=Staphylococcus aureus (strain
JH9) OX=359786 GN=der PE=3 SV=1
Length=436
Score = 38.1 bits (87), Expect = 0.25, Method: Composition-based stats.
Identities = 20/97 (21%), Positives = 35/97 (36%), Gaps = 12/97 (12%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
+IG N G++ L ++ +++ S V TTR + G+DY +
Sbjct 180 IIGRPNVGKSSLVNAILGEDR-VIVSNVAGTTRDAIDTEYSYDGQDYVLIDTA---GMRK 235
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
GK E E Y + I + L+ +
Sbjct 236 KGKVYESTE----KYSVLRA--LKAIERSNVVLVVID 266
>sp|Q2FYG0|DER_STAA8 GTPase Der OS=Staphylococcus aureus (strain
NCTC 8325 / PS 47) OX=93061 GN=der PE=3 SV=1
Length=436
Score = 38.1 bits (87), Expect = 0.25, Method: Composition-based stats.
Identities = 20/97 (21%), Positives = 35/97 (36%), Gaps = 12/97 (12%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
+IG N G++ L ++ +++ S V TTR + G+DY +
Sbjct 180 IIGRPNVGKSSLVNAILGEDR-VIVSNVAGTTRDAIDTEYSYDGQDYVLIDTA---GMRK 235
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
GK E E Y + I + L+ +
Sbjct 236 KGKVYESTE----KYSVLRA--LKAIERSNVVLVVID 266
>sp|A6U1U3|DER_STAA2 GTPase Der OS=Staphylococcus aureus (strain
JH1) OX=359787 GN=der PE=3 SV=1
Length=436
Score = 38.1 bits (87), Expect = 0.25, Method: Composition-based stats.
Identities = 20/97 (21%), Positives = 35/97 (36%), Gaps = 12/97 (12%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
+IG N G++ L ++ +++ S V TTR + G+DY +
Sbjct 180 IIGRPNVGKSSLVNAILGEDR-VIVSNVAGTTRDAIDTEYSYDGQDYVLIDTA---GMRK 235
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
GK E E Y + I + L+ +
Sbjct 236 KGKVYESTE----KYSVLRA--LKAIERSNVVLVVID 266
>sp|A7X2I1|DER_STAA1 GTPase Der OS=Staphylococcus aureus (strain
Mu3 / ATCC 700698) OX=418127 GN=der PE=3 SV=1
Length=436
Score = 38.1 bits (87), Expect = 0.25, Method: Composition-based stats.
Identities = 20/97 (21%), Positives = 35/97 (36%), Gaps = 12/97 (12%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
+IG N G++ L ++ +++ S V TTR + G+DY +
Sbjct 180 IIGRPNVGKSSLVNAILGEDR-VIVSNVAGTTRDAIDTEYSYDGQDYVLIDTA---GMRK 235
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
GK E E Y + I + L+ +
Sbjct 236 KGKVYESTE----KYSVLRA--LKAIERSNVVLVVID 266
>sp|Q7AH43|FBPC_ECO57 Fe(3+) ions import ATP-binding protein FbpC
OS=Escherichia coli O157:H7 OX=83334 GN=fbpC PE=3 SV=2
Length=348
Score = 38.1 bits (87), Expect = 0.26, Method: Composition-based stats.
Identities = 16/105 (15%), Positives = 36/105 (34%), Gaps = 8/105 (8%)
Query 478 RKRPIILIGPQNCGQNELRQRLMN-KEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAF 536
+ + + L+GP CG+ + + + ++ + + R + F S F
Sbjct 31 QGQMVTLLGPSGCGKTTILRLVAGLEKPSEGQIFIDGEDVTHRSIQQRDICMVFQSYALF 90
Query 537 EADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQS 581
E+ + + G S V+Q + K L + +
Sbjct 91 PHM----SLGENVGYGLKMLGVSRSEVKQRV---KEALAMVDLEG 128
>sp|Q54R62|UCKC_DICDI Uridine-cytidine kinase C OS=Dictyostelium
discoideum OX=44689 GN=udkC PE=3 SV=1
Length=449
Score = 38.1 bits (87), Expect = 0.26, Method: Composition-based stats.
Identities = 14/106 (13%), Positives = 37/106 (35%), Gaps = 2/106 (2%)
Query 439 KKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPII-LIGPQNCGQNELRQ 497
+ K + + +D L + + + ++ + GP G+ + Q
Sbjct 10 PRPDKDDRYTIKPLKDTLSFDKGFFLAVRAIQSIRKKSQGSVIVVGIAGPSGAGKTSIAQ 69
Query 498 RLMNKEKDRFASAVPHTTRSRRD-QEVAGRDYHFVSRQAFEADIAA 542
++++ ++ + S R E DY V + + +I+
Sbjct 70 KIVSVLPKSILISLDNYLDSSRQIIEENYDDYRLVDFELLKKNISD 115
>sp|Q8D4Q0|RSGA2_VIBVU Small ribosomal subunit biogenesis GTPase
RsgA 2 OS=Vibrio vulnificus (strain CMCP6) OX=216895 GN=rsgA2
PE=3 SV=1
Length=349
Score = 38.1 bits (87), Expect = 0.26, Method: Composition-based stats.
Identities = 14/69 (20%), Positives = 24/69 (35%), Gaps = 11/69 (16%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFE 537
+ R + IG G++ L L+ +E + T R+ + GR +
Sbjct 186 KGRTVAFIGSSGVGKSTLTNTLLGEETQQ--------TGGIREDDSKGRH---TTTARSV 234
Query 538 ADIAAGKFI 546
I G I
Sbjct 235 HMIPDGALI 243
>sp|Q8CP62|DER_STAES GTPase Der OS=Staphylococcus epidermidis
(strain ATCC 12228 / FDA PCI 1200) OX=176280 GN=der PE=3 SV=1
Length=436
Score = 38.1 bits (87), Expect = 0.26, Method: Composition-based stats.
Identities = 21/97 (22%), Positives = 36/97 (37%), Gaps = 12/97 (12%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
+IG N G++ L ++ +E+ S V TTR + G+DY +
Sbjct 180 IIGRPNVGKSSLVNAILGEER-VIVSNVAGTTRDAIDTEYSYDGQDYVLIDTA---GMRK 235
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
GK E E Y + I ++ L+ +
Sbjct 236 KGKVYESTE----KYSVLRA--LKAIERSEVVLVVID 266
>sp|Q5HP70|DER_STAEQ GTPase Der OS=Staphylococcus epidermidis
(strain ATCC 35984 / RP62A) OX=176279 GN=der PE=3 SV=1
Length=436
Score = 38.1 bits (87), Expect = 0.26, Method: Composition-based stats.
Identities = 21/97 (22%), Positives = 36/97 (37%), Gaps = 12/97 (12%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
+IG N G++ L ++ +E+ S V TTR + G+DY +
Sbjct 180 IIGRPNVGKSSLVNAILGEER-VIVSNVAGTTRDAIDTEYSYDGQDYVLIDTA---GMRK 235
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
GK E E Y + I ++ L+ +
Sbjct 236 KGKVYESTE----KYSVLRA--LKAIERSEVVLVVID 266
>sp|Q7N702|DER_PHOLL GTPase Der OS=Photorhabdus laumondii subsp.
laumondii (strain DSM 15139 / CIP 105565 / TT01) OX=243265
GN=der PE=3 SV=1
Length=493
Score = 38.1 bits (87), Expect = 0.26, Method: Composition-based stats.
Identities = 24/106 (23%), Positives = 40/106 (38%), Gaps = 12/106 (11%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVS 532
P+ + ++G N G++ L R++ +E+ +P TTR E GR+Y +
Sbjct 202 PSTLPLKLAIVGKPNVGKSTLTNRILGEER-VVVYDMPGTTRDSIYIPMERDGREYILID 260
Query 533 RQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
GK E E S+ Q I + LL +
Sbjct 261 TA---GVRKRGKITETVEKF------SVIKTLQAIEDANVVLLVID 297
>sp|Q7NQN5|POTA_CHRVO Spermidine/putrescine import ATP-binding
protein PotA OS=Chromobacterium violaceum (strain ATCC 12472
/ DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
OX=243365 GN=potA PE=3 SV=1
Length=361
Score = 38.1 bits (87), Expect = 0.27, Method: Composition-based stats.
Identities = 14/75 (19%), Positives = 22/75 (29%), Gaps = 1/75 (1%)
Query 466 YEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMN-KEKDRFASAVPHTTRSRRDQEVA 524
Y ++ L GP CG+ L + L ++ D + S+ E
Sbjct 16 YTAVNDVSLSVEAGEFFTLPGPSGCGKTTLLRMLAGFEQPDAGQILLDGQDMSQVAPEKR 75
Query 525 GRDYHFVSRQAFEAD 539
F S F
Sbjct 76 PVHTVFQSYALFPHM 90
>sp|Q87R16|MSBA_VIBPA ATP-dependent lipid A-core flippase OS=Vibrio
parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
OX=223926 GN=msbA PE=3 SV=1
Length=582
Score = 38.1 bits (87), Expect = 0.27, Method: Composition-based stats.
Identities = 17/85 (20%), Positives = 33/85 (39%), Gaps = 4/85 (5%)
Query 438 AKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQ 497
K ++ K + + + Y E E +S R + + L+G G++ +
Sbjct 331 GKYTVERAKGDVSVKDVSFTYVGSEKPALEHVSF---DIPRGKTVALVGRSGSGKSTIAN 387
Query 498 RLMNKEKDRFASAVPHTTRSRRDQE 522
L N+ D + ++ R RD E
Sbjct 388 -LFNRFYDVDSGSITLDGRDIRDYE 411
>sp|Q80TE4|SI1L2_MOUSE Signal-induced proliferation-associated
1-like protein 2 OS=Mus musculus OX=10090 GN=Sipa1l2 PE=1 SV=3
Length=1722
Score = 38.5 bits (88), Expect = 0.27, Method: Composition-based stats.
Identities = 22/111 (20%), Positives = 44/111 (40%), Gaps = 5/111 (5%)
Query 274 EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
+ + ++ + G A K+G L +G ++EI + + ++ DLL T+ V+I
Sbjct 967 NFEGI-VADVEPFGFAWKAG-LRQGSRLVEICKVAVATLTHEQMIDLLR-TSVTVKVVII 1023
Query 334 PSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ 384
+ P + + +Y D PC E F++ H +
Sbjct 1024 QPHEDGSPRRGCSELCRIPMVEY-KLDSEGTPC-EYKTPFRRNTTWHRVPT 1072
>sp|P08487|PLCG1_BOVIN 1-phosphatidylinositol 4,5-bisphosphate
phosphodiesterase gamma-1 OS=Bos taurus OX=9913 GN=PLCG1 PE=1
SV=1
Length=1291
Score = 38.5 bits (88), Expect = 0.27, Method: Composition-based stats.
Identities = 19/81 (23%), Positives = 30/81 (37%), Gaps = 12/81 (15%)
Query 334 PSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAY 393
P ++ P VKA FDY RE L+F K I+ + +++ WW
Sbjct 780 PGFYVEANPMPTFKCAVKALFDYKAQ-------REDELTFTKSAIIQNVEKQEGGWW--- 829
Query 394 REGDEDNQPLAGLVPGKSFQQ 414
GD + P ++
Sbjct 830 -RGDYGGKKQL-WFPSNYVEE 848
>sp|Q9HLP8|Y179_THEAC UPF0200 protein Ta0179 OS=Thermoplasma acidophilum
(strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155
/ AMRC-C165) OX=273075 GN=Ta0179 PE=3 SV=2
Length=181
Score = 37.0 bits (84), Expect = 0.28, Method: Composition-based stats.
Identities = 28/196 (14%), Positives = 67/196 (34%), Gaps = 38/196 (19%)
Query 481 PIILIGPQNCGQNELRQ--RLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
I++ G G++E + R + + V ++ E+ +F + + +
Sbjct 1 MIVVTGMPGAGKDEFVKVARSLGFIDLHMGNTVREFAKNAGIPEIDHEIGNFATSERKKY 60
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSD--------L 590
+ + + +++ + G+ + L+
Sbjct 61 GMDI-----WA----------VRTAQKITDDGRTVI-----DGLRNYEELQYFSKFSENP 100
Query 591 KPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEK-TREMEQNNGH---YFDTAIVNS 646
IF S++ + + K + + E+IE+ TRE+ G+ D IVN
Sbjct 101 YVVAIF---ASRKDRFSRILKRDRPDDIRTMEELIERDTRELSWGIGNVIALADYMIVND 157
Query 647 D-LDKAYQELLRLINK 661
D L+ + +L+ +
Sbjct 158 DTLETFHARCRKLLTE 173
>sp|P49983|KADH_TRIVA Adenylate kinase OS=Trichomonas vaginalis
OX=5722 PE=1 SV=1
Length=229
Score = 37.3 bits (85), Expect = 0.28, Method: Composition-based stats.
Identities = 8/40 (20%), Positives = 19/40 (48%), Gaps = 1/40 (3%)
Query 478 RKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRS 517
+ R ++ GP G+ + +L+ KE + + + R+
Sbjct 14 KDRMVVFFGPPGVGKGT-QAKLLEKEFNLYQISTGDALRA 52
>sp|Q030L6|DER_LACLS GTPase Der OS=Lactococcus lactis subsp. cremoris
(strain SK11) OX=272622 GN=der PE=3 SV=1
Length=436
Score = 38.1 bits (87), Expect = 0.28, Method: Composition-based stats.
Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 17/99 (17%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ--AFEADIA 541
LIG N G++ L ++ +++ AS + TTR D HFV + F I
Sbjct 179 LIGRPNVGKSSLINAILGEDR-VIASPIAGTTR-------DAIDTHFVDSEDQEFV-MID 229
Query 542 AGKFIEHGEFEKNLYGTSIDSV---RQVINSGKICLLSL 577
+ G+ +N T SV + I+ I L+ +
Sbjct 230 TAGMRKSGKIYEN---TEKYSVMRAMRAIDRSDIVLMVI 265
>sp|A2RM49|DER_LACLM GTPase Der OS=Lactococcus lactis subsp. cremoris
(strain MG1363) OX=416870 GN=der PE=3 SV=1
Length=436
Score = 38.1 bits (87), Expect = 0.28, Method: Composition-based stats.
Identities = 25/99 (25%), Positives = 41/99 (41%), Gaps = 17/99 (17%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ--AFEADIA 541
LIG N G++ L ++ +++ AS + TTR D HFV + F I
Sbjct 179 LIGRPNVGKSSLINAILGEDR-VIASPIAGTTR-------DAIDTHFVDSEDQEFV-MID 229
Query 542 AGKFIEHGEFEKNLYGTSIDSV---RQVINSGKICLLSL 577
+ G+ +N T SV + I+ I L+ +
Sbjct 230 TAGMRKSGKIYEN---TEKYSVMRAMRAIDRSDIVLMVI 265
>sp|P34712|PGP1_CAEEL Multidrug resistance protein pgp-1 OS=Caenorhabditis
elegans OX=6239 GN=pgp-1 PE=1 SV=2
Length=1321
Score = 38.5 bits (88), Expect = 0.28, Method: Composition-based stats.
Identities = 14/76 (18%), Positives = 27/76 (36%), Gaps = 1/76 (1%)
Query 433 GKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQ 492
K+ +K+K KN + E E + + + L+GP CG+
Sbjct 1059 SKIDSLSLAGEKKKLYGKVIFKNVRFAYPERPEIEILKGLSFSVEPGQTLALVGPSGCGK 1118
Query 493 NELRQRLMNKEKDRFA 508
+ + L+ + D
Sbjct 1119 STVV-ALLERFYDTLG 1133
Score = 36.6 bits (83), Expect = 1.1, Method: Composition-based stats.
Identities = 12/76 (16%), Positives = 28/76 (37%), Gaps = 3/76 (4%)
Query 426 DKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEMSLYHQPANRKRPIILI 485
D++P +K+ K + + ++ M+L N + + L+
Sbjct 394 DRKPVIDSSSKAGRKDMKIKGDITVENVHFTYPSRPDVPILRGMNL---RVNAGQTVALV 450
Query 486 GPQNCGQNELRQRLMN 501
G CG++ + L+
Sbjct 451 GSSGCGKSTIISLLLR 466
>sp|Q08EC4|CASS4_MOUSE Cas scaffolding protein family member 4
OS=Mus musculus OX=10090 GN=Cass4 PE=1 SV=1
Length=804
Score = 38.1 bits (87), Expect = 0.28, Method: Composition-based stats.
Identities = 19/60 (32%), Positives = 26/60 (43%), Gaps = 10/60 (17%)
Query 361 DPYVPCRELGLSFQKGDILHVISQEDP---NWWQAYREGDEDNQPLAGLVPGKSFQQQRE 417
D + C + L+F +GDIL ++ Q P WW+ G GL P Q RE
Sbjct 21 DNHADCSD-ELAFSRGDILTIVEQNVPESEGWWRCLLHG------RQGLAPANRLQVLRE 73
>sp|P49796|RGS3_HUMAN Regulator of G-protein signaling 3 OS=Homo
sapiens OX=9606 GN=RGS3 PE=1 SV=2
Length=1198
Score = 38.5 bits (88), Expect = 0.28, Method: Composition-based stats.
Identities = 28/121 (23%), Positives = 52/121 (43%), Gaps = 5/121 (4%)
Query 223 AHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISR 282
H KVA + ++ R+ G+ +KI I + +D G T+ + V +
Sbjct 267 KHLKVARRRLRPLRDPLLRMPGGGDTENGKKLKIT-IPRGKD-GFGFTICCD-SPVRVQA 323
Query 283 IVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVL-IPSQQIKPP 341
+ GG AE++G L + D VL++N + E+ + + ++ Q+KP
Sbjct 324 VDSGGPAERAG-LQQLDTVLQLNERPVEHWKCVELAHEIRSCPSEIILLVWRMVPQVKPG 382
Query 342 P 342
P
Sbjct 383 P 383
>sp|P46062|SIPA1_MOUSE Signal-induced proliferation-associated
protein 1 OS=Mus musculus OX=10090 GN=Sipa1 PE=1 SV=2
Length=1037
Score = 38.1 bits (87), Expect = 0.29, Method: Composition-based stats.
Identities = 19/137 (14%), Positives = 43/137 (31%), Gaps = 11/137 (8%)
Query 243 YESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSV---------IISRIVKGGAAEKSG 293
+ GQ GE V +++ + + I+ + + AE +G
Sbjct 657 DGAPGQAVGEVVARLQLVSRGCETRELALPRDGQGRLGFEVDAEGFITHVERFTFAETTG 716
Query 294 LLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAH 353
L G +L + G + +L + ++P + P + +++ +
Sbjct 717 -LRPGARLLRVCGQTLPKLGPETAAQMLRSAPK-VCVTVLPPDESGRPRRSFSELYMLSL 774
Query 354 FDYDPSDDPYVPCRELG 370
+ P E G
Sbjct 775 KEPSRRGGPEPVQDETG 791
>sp|O35412|SI1L1_RAT Signal-induced proliferation-associated 1-like
protein 1 OS=Rattus norvegicus OX=10116 GN=Sipa1l1 PE=1
SV=1
Length=1822
Score = 38.5 bits (88), Expect = 0.29, Method: Composition-based stats.
Identities = 22/118 (19%), Positives = 45/118 (38%), Gaps = 11/118 (9%)
Query 252 ETVKIVRIEKARDIPLGATVRNEMDSV---------IISRIVKGGAAEKSGLLHEGDEVL 302
E VK ++ + T+R I++ + G A ++G L +G ++
Sbjct 976 EIVKRLQFVSKGCESVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAG-LKQGSRLV 1034
Query 303 EINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
EI + + ++ DLL T+ V+IP P + + +Y ++
Sbjct 1035 EICKVAVATLSHEQMIDLLR-TSVTVKVVIIPPHDDCTPRRSCSETYRMPVMEYKMNE 1091
>sp|G7CBF5|IRTA_MYCT3 Mycobactin import ATP-binding/permease protein
IrtA OS=Mycolicibacterium thermoresistibile (strain ATCC
19527 / DSM 44167 / CIP 105390 / JCM 6362 / NCTC 10409 /
316) OX=1078020 GN=irtA PE=1 SV=2
Length=908
Score = 38.1 bits (87), Expect = 0.29, Method: Composition-based stats.
Identities = 17/95 (18%), Positives = 33/95 (35%), Gaps = 17/95 (18%)
Query 463 ILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQE 522
+ +++L +P L+GP G++ L L+ + D A+
Sbjct 667 VPVIRDVTLTLRP---GTVTALVGPSGSGKSTLA-ALVARFHDVTQGAI----------R 712
Query 523 VAGRDYHFVSRQAFEADIA---AGKFIEHGEFEKN 554
V GRD ++ + + HG +N
Sbjct 713 VDGRDIRTLTADELYRRVGFVLQDAQLVHGSVAEN 747
>sp|F1LRS8|CD2AP_RAT CD2-associated protein OS=Rattus norvegicus
OX=10116 GN=Cd2ap PE=1 SV=2
Length=637
Score = 38.1 bits (87), Expect = 0.29, Method: Composition-based stats.
Identities = 24/109 (22%), Positives = 44/109 (40%), Gaps = 4/109 (4%)
Query 298 GDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYD 357
GD E +++R + + + + L Q + +KA +Y
Sbjct 217 GDIFKE-GSVKLRTRTSSSETEEKKSEKPLILQSLGSRTQNVEVTKPDIDGKIKAK-EYC 274
Query 358 PSDDPYVPCRELGLSFQKGDILHVISQ--EDPNWWQAYREGDEDNQPLA 404
+ PY E L+F++G+I+H+IS+ + WW+ G E P
Sbjct 275 KTVFPYTGTNEDELTFREGEIIHLISKETGEAGWWKGELNGKEGVFPDN 323
Score = 38.1 bits (87), Expect = 0.30, Method: Composition-based stats.
Identities = 19/83 (23%), Positives = 28/83 (34%), Gaps = 13/83 (16%)
Query 332 LIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQ 391
+ P Q K K K F+Y P + E L GD++ VI + + WW
Sbjct 95 IQPHPQTKAMKKKTKKRQCKVLFEYSPQN-------EDELELTVGDVIDVIEEVEEGWWS 147
Query 392 AYREGDEDNQPLAGLVPGKSFQQ 414
GL P ++
Sbjct 148 G------TLNNKLGLFPSNFVKE 164
>sp|A2QGW1|SHO1_ASPNC High osmolarity signaling protein sho1 OS=Aspergillus
niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC
A1513) OX=425011 GN=sho1 PE=3 SV=1
Length=288
Score = 37.7 bits (86), Expect = 0.29, Method: Composition-based stats.
Identities = 17/76 (22%), Positives = 26/76 (34%), Gaps = 16/76 (21%)
Query 337 QIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREG 396
Q P + I+ ++ +P D + SF K +IL V WWQA +
Sbjct 226 QPTEYPYRAKAIY---SYEANPEDANEI-------SFTKHEILEVSDVS-GRWWQARK-- 272
Query 397 DEDNQPLAGLVPGKSF 412
G+ P
Sbjct 273 ---ATGETGIAPSNYL 285
>sp|Q6BJJ8|LONP2_DEBHA Lon protease homolog 2, peroxisomal OS=Debaryomyces
hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394
/ JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=DEHA2G01892g
PE=3 SV=2
Length=1147
Score = 38.5 bits (88), Expect = 0.29, Method: Composition-based stats.
Identities = 17/119 (14%), Positives = 35/119 (29%), Gaps = 10/119 (8%)
Query 410 KSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEEM 469
K ++ +++ +NK K+ K L K+ + +
Sbjct 585 KQRSEKTFTRSDDSIVIANNDETSIAHETARNKNKKSKSLTTIEKSSLNKSLMV------ 638
Query 470 SLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDY 528
N+ I+L+GP G+ L + + F + + R Y
Sbjct 639 ----SKNNKSPIIMLVGPPGTGKTSLAKSIAKSLGRNFQRVSLGGIKDESEIRGHRRTY 693
>sp|Q1JQD4|GIPC2_BOVIN PDZ domain-containing protein GIPC2 OS=Bos
taurus OX=9913 GN=GIPC2 PE=2 SV=1
Length=313
Score = 37.7 bits (86), Expect = 0.29, Method: Composition-based stats.
Identities = 24/98 (24%), Positives = 36/98 (37%), Gaps = 6/98 (6%)
Query 255 KIVRIEKARDIPLGATVRNEMDS-VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
K V + K+ D LG T+ + I RI + + GD + ING I G
Sbjct 116 KEVNVYKSED-SLGLTITDNGAGYAFIKRIKDDSIIDSVKTICVGDHIEAINGENIVGWR 174
Query 314 VNEVFDLLSDMHG----TLTFVLIPSQQIKPPPAKETV 347
+V L ++ TLT + P +K
Sbjct 175 HFDVAKKLKELKKEELFTLTLIEPKKAFDMEPRSKAGK 212
>sp|A0JNK3|HTRA2_BOVIN Serine protease HTRA2, mitochondrial OS=Bos
taurus OX=9913 GN=HTRA2 PE=2 SV=1
Length=458
Score = 38.1 bits (87), Expect = 0.29, Method: Composition-based stats.
Identities = 13/68 (19%), Positives = 28/68 (41%), Gaps = 9/68 (13%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG--------KDVNEVFDLLSDMHGT 327
V+I +++ A ++G L GD +L I ++ + +++ + T
Sbjct 389 HGVLIHKVILDSPAHRAG-LRPGDVILAIGEQLVQNAEDIYEAVRTQSQLAVRIRRGQET 447
Query 328 LTFVLIPS 335
LT + P
Sbjct 448 LTLYVTPE 455
>sp|Q8YH20|NDVA_BRUME Beta-(1-->2)glucan export ATP-binding/permease
protein NdvA OS=Brucella melitensis biotype 1 (strain
16M / ATCC 23456 / NCTC 10094) OX=224914 GN=ndvA PE=3 SV=1
Length=599
Score = 38.1 bits (87), Expect = 0.29, Method: Composition-based stats.
Identities = 18/108 (17%), Positives = 34/108 (31%), Gaps = 18/108 (17%)
Query 448 VLYNANKNDDYDNEEILTYE---------EMSLYHQPANRKRPIILIGPQNCGQNELRQR 498
L + + +DN +TYE ++S +P + + ++GP G+ L
Sbjct 327 DLNDVKGDIVFDN---VTYEFPNSGQGVYDVSFEVKP---GQTVAIVGPTGAGKTTLINL 380
Query 499 LMNKEKDRFASAVPHTTRSRRDQEVAGRDYH---FVSRQAFEADIAAG 543
L + T +R + R F F +
Sbjct 381 LQRVFDPAAGRIMIDGTDTRTVSRRSLRHAIATVFQDAGLFNRSVEDN 428
>sp|P0C529|NDVA_BRUAB Beta-(1-->2)glucan export ATP-binding/permease
protein NdvA OS=Brucella abortus biovar 1 (strain 9-941)
OX=262698 GN=ndvA PE=3 SV=1
Length=599
Score = 38.1 bits (87), Expect = 0.29, Method: Composition-based stats.
Identities = 18/108 (17%), Positives = 34/108 (31%), Gaps = 18/108 (17%)
Query 448 VLYNANKNDDYDNEEILTYE---------EMSLYHQPANRKRPIILIGPQNCGQNELRQR 498
L + + +DN +TYE ++S +P + + ++GP G+ L
Sbjct 327 DLNDVKGDIVFDN---VTYEFPNSGQGVYDVSFEVKP---GQTVAIVGPTGAGKTTLINL 380
Query 499 LMNKEKDRFASAVPHTTRSRRDQEVAGRDYH---FVSRQAFEADIAAG 543
L + T +R + R F F +
Sbjct 381 LQRVFDPAAGRIMIDGTDTRTVSRRSLRHAIATVFQDAGLFNRSVEDN 428
>sp|Q2YQ73|NDVA_BRUA2 Beta-(1-->2)glucan export ATP-binding/permease
protein NdvA OS=Brucella abortus (strain 2308) OX=359391
GN=ndvA PE=1 SV=1
Length=599
Score = 38.1 bits (87), Expect = 0.29, Method: Composition-based stats.
Identities = 18/108 (17%), Positives = 34/108 (31%), Gaps = 18/108 (17%)
Query 448 VLYNANKNDDYDNEEILTYE---------EMSLYHQPANRKRPIILIGPQNCGQNELRQR 498
L + + +DN +TYE ++S +P + + ++GP G+ L
Sbjct 327 DLNDVKGDIVFDN---VTYEFPNSGQGVYDVSFEVKP---GQTVAIVGPTGAGKTTLINL 380
Query 499 LMNKEKDRFASAVPHTTRSRRDQEVAGRDYH---FVSRQAFEADIAAG 543
L + T +R + R F F +
Sbjct 381 LQRVFDPAAGRIMIDGTDTRTVSRRSLRHAIATVFQDAGLFNRSVEDN 428
>sp|Q1GID1|UGPC_RUEST sn-glycerol-3-phosphate import ATP-binding
protein UgpC OS=Ruegeria sp. (strain TM1040) OX=292414 GN=ugpC
PE=3 SV=1
Length=351
Score = 37.7 bits (86), Expect = 0.30, Method: Composition-based stats.
Identities = 9/41 (22%), Positives = 20/41 (49%), Gaps = 3/41 (7%)
Query 463 ILTYEEMSLYHQ---PANRKRPIILIGPQNCGQNELRQRLM 500
+ +Y + + H N I+++GP CG++ L + +
Sbjct 10 VKSYGDTEVLHHIDGEINDGEFIVIVGPSGCGKSTLLRMIA 50
>sp|A6TRW0|RSGA_ALKMQ Small ribosomal subunit biogenesis GTPase
RsgA OS=Alkaliphilus metalliredigens (strain QYMF) OX=293826
GN=rsgA PE=3 SV=1
Length=292
Score = 37.7 bits (86), Expect = 0.30, Method: Composition-based stats.
Identities = 6/23 (26%), Positives = 12/23 (52%), Gaps = 0/23 (0%)
Query 478 RKRPIILIGPQNCGQNELRQRLM 500
R + + GP G++ L R++
Sbjct 157 RGKTTVFAGPSGVGKSTLLNRIL 179
>sp|O67322|NTPTH_AQUAE Nucleoside-triphosphatase THEP1 OS=Aquifex
aeolicus (strain VF5) OX=224324 GN=aq_1292 PE=1 SV=1
Length=178
Score = 36.6 bits (83), Expect = 0.30, Method: Composition-based stats.
Identities = 16/86 (19%), Positives = 33/86 (38%), Gaps = 4/86 (5%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
II+ G G+ L ++++ + A+ T RD E R + + I
Sbjct 3 IIITGEPGVGKTTLVKKIVERLG---KRAIGFWTEEVRDPETKKRTGFRIITTEGKKKIF 59
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVI 567
+ KF + + YG ++ ++
Sbjct 60 SSKFFTSKKLVGS-YGVNVQYFEELA 84
>sp|Q8UB29|UGPC3_AGRFC sn-glycerol-3-phosphate import ATP-binding
protein UgpC 3 OS=Agrobacterium fabrum (strain C58 / ATCC
33970) OX=176299 GN=ugpC3 PE=3 SV=1
Length=353
Score = 37.7 bits (86), Expect = 0.30, Method: Composition-based stats.
Identities = 8/34 (24%), Positives = 15/34 (44%), Gaps = 0/34 (0%)
Query 467 EEMSLYHQPANRKRPIILIGPQNCGQNELRQRLM 500
E + I+L+GP CG++ L + +
Sbjct 18 EAIKSVSMEIADGEMIVLVGPSGCGKSTLLRMIA 51
>sp|Q8BZT2|SH3R2_MOUSE E3 ubiquitin-protein ligase SH3RF2 OS=Mus
musculus OX=10090 GN=Sh3rf2 PE=1 SV=2
Length=735
Score = 38.1 bits (87), Expect = 0.31, Method: Composition-based stats.
Identities = 27/153 (18%), Positives = 55/153 (36%), Gaps = 30/153 (20%)
Query 303 EINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDP 362
EING+ G +++ + +PPP +A +++D D
Sbjct 166 EINGVS--GIFPASSVEVIKQLP-------------QPPPL------CRALYNFDLRDKD 204
Query 363 YVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPG---KSFQQQR--- 416
++ L+F K D++ VIS+ D NW + P+ + P + + +
Sbjct 205 KSENQDC-LTFLKDDVITVISRVDENWAEGKLGDKVGIFPILFVEPNVSARHLLENKGHQ 263
Query 417 --EAMKQTIEEDKEPEKSGKLWCAKKNKKKRKK 447
++ K+ +K+ R+K
Sbjct 264 LSRTRHLSLMSSPSRGKATNTSSLRKSPGSRRK 296
>sp|Q7T2D0|SGSM3_DANRE Small G protein signaling modulator 3 OS=Danio
rerio OX=7955 GN=sgsm3 PE=2 SV=1
Length=755
Score = 38.1 bits (87), Expect = 0.31, Method: Composition-based stats.
Identities = 20/78 (26%), Positives = 31/78 (40%), Gaps = 13/78 (17%)
Query 336 QQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYRE 395
+ ++ KA D++ DD L F+K DI+ +ISQ+D + W
Sbjct 475 HENFLVVSRNRRRRAKALLDFERHDDDE-------LGFRKNDIITIISQKDEHCWVGELN 527
Query 396 GDEDNQPLAGLVPGKSFQ 413
G L G P K +
Sbjct 528 G------LRGWFPAKFVE 539
>sp|A1WUL5|DER_HALHL GTPase Der OS=Halorhodospira halophila (strain
DSM 244 / SL1) OX=349124 GN=der PE=3 SV=1
Length=472
Score = 38.1 bits (87), Expect = 0.31, Method: Composition-based stats.
Identities = 26/125 (21%), Positives = 42/125 (34%), Gaps = 23/125 (18%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRS--RRDQEVAGRDYHFVSRQAFEA 538
P+ +IG N G++ L RL+ +E+ P TTR E G+ Y +
Sbjct 179 PVAMIGRPNVGKSTLVNRLLGEER-VVVYDEPGTTRDSIAVPFERDGQHYTLIDTAGVRR 237
Query 539 DIAAGKFIEHGEFEKNLYGTSIDSV------------RQ-------VINSGKICLLSLR- 578
+ +E K L SV Q V+ +G+ +L +
Sbjct 238 RARVQETVEKFSVVKTLEAIERASVVMLVTDAQEGITEQDAHLAGHVLQAGRALVLVINK 297
Query 579 TQSLK 583
L
Sbjct 298 WDGLD 302
>sp|Q498D9|GIPC2_RAT PDZ domain-containing protein GIPC2 OS=Rattus
norvegicus OX=10116 GN=Gipc2 PE=2 SV=1
Length=314
Score = 37.7 bits (86), Expect = 0.31, Method: Composition-based stats.
Identities = 20/65 (31%), Positives = 27/65 (42%), Gaps = 2/65 (3%)
Query 255 KIVRIEKARDIPLGATVRNEMDS-VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKD 313
K V + K+ D LG T+ + I RI G + + GD + ING I G
Sbjct 116 KEVNVYKSED-SLGLTITDNGVGYAFIKRIKDGSTIDSVKTICVGDHIECINGENIVGWR 174
Query 314 VNEVF 318
EV
Sbjct 175 HFEVA 179
>sp|B7LLU5|RSGA_ESCF3 Small ribosomal subunit biogenesis GTPase
RsgA OS=Escherichia fergusonii (strain ATCC 35469 / DSM 13698
/ CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419
/ NCTC 12128 / CDC 0568-73) OX=585054 GN=rsgA PE=3 SV=1
Length=350
Score = 37.7 bits (86), Expect = 0.31, Method: Composition-based stats.
Identities = 14/57 (25%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + V + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHF 258
>sp|B1LQI4|RSGA_ECOSM Small ribosomal subunit biogenesis GTPase
RsgA OS=Escherichia coli (strain SMS-3-5 / SECEC) OX=439855
GN=rsgA PE=3 SV=1
Length=350
Score = 37.7 bits (86), Expect = 0.31, Method: Composition-based stats.
Identities = 14/57 (25%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + V + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHF 258
>sp|A1AT90|MIAA1_PELPD tRNA dimethylallyltransferase 1 OS=Pelobacter
propionicus (strain DSM 2379 / NBRC 103807 / OttBd1)
OX=338966 GN=miaA1 PE=3 SV=1
Length=309
Score = 37.7 bits (86), Expect = 0.31, Method: Composition-based stats.
Identities = 25/157 (16%), Positives = 50/157 (32%), Gaps = 23/157 (15%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHT--------TRSRRDQEVAGRDYHF 530
R +I+ GP G++EL RL + +A T E+ +H
Sbjct 7 PRILIICGPTASGKSELAVRLARELDGEIVNADSMQIHRGMDIGTAKPTVGEMGAVPHHL 66
Query 531 VSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDL 590
+ + +A F + ++ +I GK + + L
Sbjct 67 LDVADPDRPFSAADFSDAAS----------QAISGIIRRGKRP---IVVGGTGLYLRALL 113
Query 591 KPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEK 627
+ +P LR L +E + + + E + +
Sbjct 114 HGLV--DSPSGAGELRRRLQEEARELGNQAMLERLRR 148
>sp|P9WQJ3|FATRP_MYCTU Fatty acid ABC transporter ATP-binding/permease
protein OS=Mycobacterium tuberculosis (strain ATCC
25618 / H37Rv) OX=83332 GN=Rv1272c PE=1 SV=1
Length=631
Score = 38.1 bits (87), Expect = 0.31, Method: Composition-based stats.
Identities = 22/117 (19%), Positives = 44/117 (38%), Gaps = 18/117 (15%)
Query 464 LTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV 523
++SL +P + ++GP G+ L LM + S R +
Sbjct 411 PVIRDLSLVAEP---GSTVAIVGPTGAGKTTLVNLLMR----------FYEIGSGRI-LI 456
Query 524 AGRDYHFVSRQAFEADIA---AGKFIEHGEFEKNL-YGTSIDSVRQVINSGKICLLS 576
G D VSRQ+ + I ++ G +N+ YG + +++ + + +
Sbjct 457 DGVDIASVSRQSLRSRIGMVLQDTWLYDGTIAENIAYGRPEATTDEIVEAARAAHVD 513
>sp|P9WQJ2|FATRP_MYCTO Fatty acid ABC transporter ATP-binding/permease
protein OS=Mycobacterium tuberculosis (strain CDC 1551
/ Oshkosh) OX=83331 GN=MT1310 PE=3 SV=1
Length=631
Score = 38.1 bits (87), Expect = 0.31, Method: Composition-based stats.
Identities = 22/117 (19%), Positives = 44/117 (38%), Gaps = 18/117 (15%)
Query 464 LTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV 523
++SL +P + ++GP G+ L LM + S R +
Sbjct 411 PVIRDLSLVAEP---GSTVAIVGPTGAGKTTLVNLLMR----------FYEIGSGRI-LI 456
Query 524 AGRDYHFVSRQAFEADIA---AGKFIEHGEFEKNL-YGTSIDSVRQVINSGKICLLS 576
G D VSRQ+ + I ++ G +N+ YG + +++ + + +
Sbjct 457 DGVDIASVSRQSLRSRIGMVLQDTWLYDGTIAENIAYGRPEATTDEIVEAARAAHVD 513
>sp|P63398|FATRP_MYCBO Fatty acid ABC transporter ATP-binding/permease
protein OS=Mycobacterium bovis (strain ATCC BAA-935
/ AF2122/97) OX=233413 GN=BQ2027_MB1303C PE=3 SV=1
Length=631
Score = 38.1 bits (87), Expect = 0.31, Method: Composition-based stats.
Identities = 22/117 (19%), Positives = 44/117 (38%), Gaps = 18/117 (15%)
Query 464 LTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV 523
++SL +P + ++GP G+ L LM + S R +
Sbjct 411 PVIRDLSLVAEP---GSTVAIVGPTGAGKTTLVNLLMR----------FYEIGSGRI-LI 456
Query 524 AGRDYHFVSRQAFEADIA---AGKFIEHGEFEKNL-YGTSIDSVRQVINSGKICLLS 576
G D VSRQ+ + I ++ G +N+ YG + +++ + + +
Sbjct 457 DGVDIASVSRQSLRSRIGMVLQDTWLYDGTIAENIAYGRPEATTDEIVEAARAAHVD 513
>sp|B7M8S4|RSGA_ECO8A Small ribosomal subunit biogenesis GTPase
RsgA OS=Escherichia coli O8 (strain IAI1) OX=585034 GN=rsgA
PE=3 SV=1
Length=350
Score = 37.7 bits (86), Expect = 0.32, Method: Composition-based stats.
Identities = 14/57 (25%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + V + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHF 258
>sp|Q8X5I6|TAUB_ECO57 Taurine import ATP-binding protein TauB
OS=Escherichia coli O157:H7 OX=83334 GN=tauB PE=3 SV=1
Length=255
Score = 37.3 bits (85), Expect = 0.32, Method: Composition-based stats.
Identities = 18/133 (14%), Positives = 40/133 (30%), Gaps = 22/133 (17%)
Query 464 LTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV 523
E+++L ++++GP CG+ L + + S R
Sbjct 15 PVLEDINL---TLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSIQLAGKRIEGPGAE 71
Query 524 AGRDYHFVSRQAFEADIAAGKFIEHGEFEKNL-YGTSIDSVRQVINSGKICLLSLRTQSL 582
G F+ + + N+ +G + + ++ L + Q L
Sbjct 72 RGV--------VFQ----NEGLLPWRNVQDNVAFGLQLAGIEKMQR------LEIAHQML 113
Query 583 KTLRNSDLKPYII 595
K + + I
Sbjct 114 KKVGLEGAEKRYI 126
>sp|Q13625|ASPP2_HUMAN Apoptosis-stimulating of p53 protein 2
OS=Homo sapiens OX=9606 GN=TP53BP2 PE=1 SV=2
Length=1128
Score = 38.1 bits (87), Expect = 0.32, Method: Composition-based stats.
Identities = 23/83 (28%), Positives = 35/83 (42%), Gaps = 14/83 (17%)
Query 331 VLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGD---ILHVISQEDP 387
+ Q K + VI+ A +DY+P +D +P +E GD I+H +++
Sbjct 1045 QFLYGVQEKMGIMNKGVIY--ALWDYEPQNDDELPMKE-------GDCMTIIHREDEDEI 1095
Query 388 NWWQAYREGDEDNQPLA--GLVP 408
WW A E P GL P
Sbjct 1096 EWWWARLNDKEGYVPRNLLGLYP 1118
>sp|B2TY39|RSGA_SHIB3 Small ribosomal subunit biogenesis GTPase
RsgA OS=Shigella boydii serotype 18 (strain CDC 3083-94 /
BS512) OX=344609 GN=rsgA PE=3 SV=1
Length=350
Score = 37.7 bits (86), Expect = 0.32, Method: Composition-based stats.
Identities = 14/57 (25%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + V + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHF 258
>sp|B6I268|RSGA_ECOSE Small ribosomal subunit biogenesis GTPase
RsgA OS=Escherichia coli (strain SE11) OX=409438 GN=rsgA PE=3
SV=1
Length=350
Score = 37.7 bits (86), Expect = 0.32, Method: Composition-based stats.
Identities = 14/57 (25%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + V + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHF 258
>sp|A8A7Q8|RSGA_ECOHS Small ribosomal subunit biogenesis GTPase
RsgA OS=Escherichia coli O9:H4 (strain HS) OX=331112 GN=rsgA
PE=3 SV=1
Length=350
Score = 37.7 bits (86), Expect = 0.32, Method: Composition-based stats.
Identities = 14/57 (25%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + V + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHF 258
>sp|B5Z2H0|RSGA_ECO5E Small ribosomal subunit biogenesis GTPase
RsgA OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) OX=444450
GN=rsgA PE=3 SV=1
Length=350
Score = 37.7 bits (86), Expect = 0.32, Method: Composition-based stats.
Identities = 14/57 (25%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + V + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHF 258
>sp|Q8XDP1|RSGA_ECO57 Small ribosomal subunit biogenesis GTPase
RsgA OS=Escherichia coli O157:H7 OX=83334 GN=rsgA PE=3 SV=2
Length=350
Score = 37.7 bits (86), Expect = 0.32, Method: Composition-based stats.
Identities = 14/57 (25%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + V + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHF 258
>sp|B7LC22|RSGA_ECO55 Small ribosomal subunit biogenesis GTPase
RsgA OS=Escherichia coli (strain 55989 / EAEC) OX=585055 GN=rsgA
PE=3 SV=1
Length=350
Score = 37.7 bits (86), Expect = 0.32, Method: Composition-based stats.
Identities = 14/57 (25%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + V + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHF 258
>sp|A7ZV32|RSGA_ECO24 Small ribosomal subunit biogenesis GTPase
RsgA OS=Escherichia coli O139:H28 (strain E24377A / ETEC)
OX=331111 GN=rsgA PE=3 SV=1
Length=350
Score = 37.7 bits (86), Expect = 0.32, Method: Composition-based stats.
Identities = 14/57 (25%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + V + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHF 258
>sp|Q3UND0|SKAP2_MOUSE Src kinase-associated phosphoprotein 2
OS=Mus musculus OX=10090 GN=Skap2 PE=1 SV=2
Length=358
Score = 37.7 bits (86), Expect = 0.32, Method: Composition-based stats.
Identities = 14/46 (30%), Positives = 24/46 (52%), Gaps = 8/46 (17%)
Query 371 LSFQKGDILHVISQEDP--NWWQAYREGDEDNQPLAGLVPGKSFQQ 414
LSF++GD+++++S+E WW +G GLVP +
Sbjct 315 LSFKRGDVIYILSKEYNRYGWWVGEMKG------AIGLVPKAYLME 354
>sp|Q1IEH7|DER_PSEE4 GTPase Der OS=Pseudomonas entomophila (strain
L48) OX=384676 GN=der PE=3 SV=1
Length=488
Score = 37.7 bits (86), Expect = 0.32, Method: Composition-based stats.
Identities = 25/122 (20%), Positives = 44/122 (36%), Gaps = 13/122 (11%)
Query 460 NEEILTYEEMSLYHQPANR-KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR 518
+E++ EE + P+ + I +IG N G++ L R++ +E+ P TTR
Sbjct 172 DEDVAEGEEATRIPGPSEKDGIKIAIIGRPNVGKSTLVNRMLGEER-VVVYDQPGTTRDS 230
Query 519 --RDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLS 576
E G Y F+ + +E K L Q I + +
Sbjct 231 IYIPFERDGEKYTFIDTAGVRKRGKIHEEVEKFSVVKTL---------QAIKDANVVIFV 281
Query 577 LR 578
+
Sbjct 282 MD 283
>sp|P98171|RHG04_HUMAN Rho GTPase-activating protein 4 OS=Homo
sapiens OX=9606 GN=ARHGAP4 PE=1 SV=2
Length=946
Score = 38.1 bits (87), Expect = 0.32, Method: Composition-based stats.
Identities = 21/120 (18%), Positives = 40/120 (33%), Gaps = 43/120 (36%)
Query 329 TFVLIPSQQIKPPPAKETVIHVKAHF-----------------DYDPSDDPYVPCRE--- 368
T ++ P + P + ++ K D +P + +P +E
Sbjct 686 TLIVQPDRVFPPLTSLPGPVYEKCMAPPSASCLGDAQLESLGADNEPELEAEMPAQEDDL 745
Query 369 -----------------LGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKS 411
LSF++GD+L + + +WW+ G + GL+P K
Sbjct 746 EGVVEAVACFAYTGRTAQELSFRRGDVLRLHERASSDWWRGEHNG------MRGLIPHKY 799
>sp|B7NG98|RSGA_ECOLU Small ribosomal subunit biogenesis GTPase
RsgA OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)
OX=585056 GN=rsgA PE=3 SV=1
Length=350
Score = 37.7 bits (86), Expect = 0.33, Method: Composition-based stats.
Identities = 14/57 (25%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + V + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHF 258
>sp|Q8FAL3|RSGA_ECOL6 Small ribosomal subunit biogenesis GTPase
RsgA OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928
/ UPEC) OX=199310 GN=rsgA PE=3 SV=2
Length=350
Score = 37.7 bits (86), Expect = 0.33, Method: Composition-based stats.
Identities = 14/57 (25%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + V + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHF 258
>sp|B7MSX6|RSGA_ECO81 Small ribosomal subunit biogenesis GTPase
RsgA OS=Escherichia coli O81 (strain ED1a) OX=585397 GN=rsgA
PE=3 SV=1
Length=350
Score = 37.7 bits (86), Expect = 0.33, Method: Composition-based stats.
Identities = 14/57 (25%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + V + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHF 258
>sp|B7NTM0|RSGA_ECO7I Small ribosomal subunit biogenesis GTPase
RsgA OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) OX=585057
GN=rsgA PE=3 SV=1
Length=350
Score = 37.7 bits (86), Expect = 0.33, Method: Composition-based stats.
Identities = 14/57 (25%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + V + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHF 258
>sp|B7MKW8|RSGA_ECO45 Small ribosomal subunit biogenesis GTPase
RsgA OS=Escherichia coli O45:K1 (strain S88 / ExPEC) OX=585035
GN=rsgA PE=3 SV=1
Length=350
Score = 37.7 bits (86), Expect = 0.33, Method: Composition-based stats.
Identities = 14/57 (25%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + V + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHF 258
>sp|B7UPY1|RSGA_ECO27 Small ribosomal subunit biogenesis GTPase
RsgA OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC)
OX=574521 GN=rsgA PE=3 SV=1
Length=350
Score = 37.7 bits (86), Expect = 0.33, Method: Composition-based stats.
Identities = 14/57 (25%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + V + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHF 258
>sp|Q1M589|UGPC3_RHIJ3 sn-glycerol-3-phosphate import ATP-binding
protein UgpC 3 OS=Rhizobium johnstonii (strain DSM 114642
/ LMG 32736 / 3841) OX=216596 GN=ugpC3 PE=3 SV=1
Length=348
Score = 37.7 bits (86), Expect = 0.33, Method: Composition-based stats.
Identities = 27/156 (17%), Positives = 44/156 (28%), Gaps = 62/156 (40%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQA-FE 537
I+L+GP CG++ L + + E T S E+AGR+ V++ +
Sbjct 29 GELIVLVGPSGCGKSTLLRMIAGLE-----------TISEGHVEIAGRN---VNKAEPAD 74
Query 538 ADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFI 597
DI +N +VR + G
Sbjct 75 RDI--------AMVFQNYALYPHMTVRGNLEYG--------------------------- 99
Query 598 APPSQERLRALLAKEGKNPKPEELREIIEKTREMEQ 633
L G + E R + E +E
Sbjct 100 -----------LKNRGTE-RAEINRRVAEAAEILEI 123
>sp|A4WVN6|Y2562_CERS5 Nucleotide-binding protein Rsph17025_2562
OS=Cereibacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)
OX=349102 GN=Rsph17025_2562 PE=3 SV=1
Length=302
Score = 37.3 bits (85), Expect = 0.33, Method: Composition-based stats.
Identities = 7/27 (26%), Positives = 12/27 (44%), Gaps = 0/27 (0%)
Query 473 HQPANRKRPIILIGPQNCGQNELRQRL 499
+PA R +++ GP G+ L
Sbjct 2 SEPAQEYRLVLVTGPSGAGRTTAVNAL 28
>sp|P0CK24|A565_VACCW Uncharacterized protein A56.5 OS=Vaccinia
virus (strain Western Reserve) OX=10254 GN=HA PE=3 SV=1
Length=37
Score = 33.5 bits (75), Expect = 0.33, Method: Composition-based stats.
Identities = 8/18 (44%), Positives = 11/18 (61%), Gaps = 0/18 (0%)
Query 482 IILIGPQNCGQNELRQRL 499
IIL GP G+ + +RL
Sbjct 8 IILSGPSGLGKTAIAKRL 25
>sp|Q9C7X0|ADR2_ARATH Disease resistance protein ADR2 OS=Arabidopsis
thaliana OX=3702 GN=ADR2 PE=2 SV=1
Length=1007
Score = 38.1 bits (87), Expect = 0.33, Method: Composition-based stats.
Identities = 15/103 (15%), Positives = 36/103 (35%), Gaps = 6/103 (6%)
Query 411 SFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEILTYEE-- 468
+ +A+ + + AK +K + V N D ++++ E
Sbjct 135 ERSKWSQALTY-VGNIAGEDFIHWKDEAKMIEKIARDVSTKINVTPCRDFDDMVGLERHL 193
Query 469 ---MSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFA 508
+SL + + + GP G++ + + L ++ F
Sbjct 194 KEMVSLLDLDKEGVKMVGISGPAGIGKSTIAKALHSRHSSTFQ 236
>sp|B0KPJ1|DER_PSEPG GTPase Der OS=Pseudomonas putida (strain
GB-1) OX=76869 GN=der PE=3 SV=1
Length=487
Score = 37.7 bits (86), Expect = 0.34, Method: Composition-based stats.
Identities = 26/127 (20%), Positives = 45/127 (35%), Gaps = 13/127 (10%)
Query 455 NDDYDNEEILTYEEMSLYHQPANR-KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPH 513
D+ ++E+ EE P+ + I +IG N G++ L R++ +E+ P
Sbjct 167 EDEALDQEVAEGEEAVRIPGPSEKDGIKIAIIGRPNVGKSTLVNRMLGEER-VVVYDEPG 225
Query 514 TTRSR--RDQEVAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGK 571
TTR E G Y F+ + +E K L Q I
Sbjct 226 TTRDSIYIPFERDGEKYTFIDTAGVRKRGKIHEEVEKFSVVKTL---------QAIKDAN 276
Query 572 ICLLSLR 578
+ + +
Sbjct 277 VVIFVMD 283
>sp|A5D8S5|SH3R1_DANRE E3 ubiquitin-protein ligase SH3RF1 OS=Danio
rerio OX=7955 GN=sh3rf1 PE=2 SV=2
Length=867
Score = 38.1 bits (87), Expect = 0.34, Method: Composition-based stats.
Identities = 27/161 (17%), Positives = 52/161 (32%), Gaps = 21/161 (13%)
Query 331 VLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW 390
V+ P Q P KA +D++ D L F K DIL VI + D NW
Sbjct 188 VIKPLPQPPPQC--------KALYDFELKDKEADKDC---LPFSKDDILTVIRRVDENW- 235
Query 391 QAYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLY 450
+ G+ P + A + + + +
Sbjct 236 -----AEGMLGDKIGIFPISYVEFNSAARQLIELDKPSEGGGDSSEGPSSSSSGPQANGS 290
Query 451 NANKNDDYDNEEILTYEEMSLYHQPANRKRP----IILIGP 487
+ ++++ ++ +++ H+P P + + GP
Sbjct 291 QKAPGEKKNSKKRHSFTSLTMSHKPCLAPPPQRHSMEISGP 331
>sp|P39286|RSGA_ECOLI Small ribosomal subunit biogenesis GTPase
RsgA OS=Escherichia coli (strain K12) OX=83333 GN=rsgA PE=1
SV=2
Length=350
Score = 37.7 bits (86), Expect = 0.34, Method: Composition-based stats.
Identities = 13/57 (23%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + + + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDISDNSGLGQHTTTAARLYHF 258
>sp|B1IT42|RSGA_ECOLC Small ribosomal subunit biogenesis GTPase
RsgA OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC
3972 / NCIMB 8545 / WDCM 00012 / Crooks) OX=481805 GN=rsgA
PE=3 SV=1
Length=350
Score = 37.7 bits (86), Expect = 0.34, Method: Composition-based stats.
Identities = 13/57 (23%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + + + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDISDNSGLGQHTTTAARLYHF 258
>sp|B1XDR5|RSGA_ECODH Small ribosomal subunit biogenesis GTPase
RsgA OS=Escherichia coli (strain K12 / DH10B) OX=316385 GN=rsgA
PE=3 SV=1
Length=350
Score = 37.7 bits (86), Expect = 0.34, Method: Composition-based stats.
Identities = 13/57 (23%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + + + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDISDNSGLGQHTTTAARLYHF 258
>sp|C5A1F5|RSGA_ECOBW Small ribosomal subunit biogenesis GTPase
RsgA OS=Escherichia coli (strain K12 / MC4100 / BW2952) OX=595496
GN=rsgA PE=3 SV=1
Length=350
Score = 37.7 bits (86), Expect = 0.34, Method: Composition-based stats.
Identities = 13/57 (23%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ +K+ + + + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDISDNSGLGQHTTTAARLYHF 258
>sp|A6QTM4|SHO1_AJECN High osmolarity signaling protein SHO1 OS=Ajellomyces
capsulatus (strain NAm1 / WU24) OX=2059318 GN=SHO1
PE=3 SV=1
Length=292
Score = 37.3 bits (85), Expect = 0.34, Method: Composition-based stats.
Identities = 16/62 (26%), Positives = 23/62 (37%), Gaps = 11/62 (18%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
KA + Y+ + D +SF K +IL V WWQA + G+ P
Sbjct 239 KAIYSYEANPDDA-----NEISFSKHEILDVSDVS-GRWWQAKK-----ASGETGIAPSN 287
Query 411 SF 412
Sbjct 288 YL 289
>sp|Q1QTX6|UGPC_CHRSD sn-glycerol-3-phosphate import ATP-binding
protein UgpC OS=Chromohalobacter salexigens (strain ATCC
BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) OX=290398
GN=ugpC PE=3 SV=1
Length=370
Score = 37.7 bits (86), Expect = 0.34, Method: Composition-based stats.
Identities = 20/98 (20%), Positives = 34/98 (35%), Gaps = 17/98 (17%)
Query 479 KRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEA 538
I+++GP CG++ L + L E +A RR E+ A
Sbjct 30 GELIVVVGPSGCGKSTLLRILAGLEP---ITAGELAINGRRVNELE-------PAARDIA 79
Query 539 DIAAG-KFIEHGEFEKNL-Y-----GTSIDSVRQVINS 569
+ H N+ Y GT D +R+ + +
Sbjct 80 MVFQNYALYPHMSVAGNMAYALKNRGTPKDEIRRRVAN 117
>sp|O94875|SRBS2_HUMAN Sorbin and SH3 domain-containing protein
2 OS=Homo sapiens OX=9606 GN=SORBS2 PE=1 SV=3
Length=1100
Score = 38.1 bits (87), Expect = 0.35, Method: Composition-based stats.
Identities = 17/82 (21%), Positives = 37/82 (45%), Gaps = 7/82 (9%)
Query 325 HGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ 384
TLT + + + + ++ + KA +D+ LSF+KGD ++++ +
Sbjct 843 SSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKE-------LSFKKGDTVYILRK 895
Query 385 EDPNWWQAYREGDEDNQPLAGL 406
D NW++ G P++ +
Sbjct 896 IDQNWYEGEHHGRVGIFPISYV 917
>sp|Q8ETB7|RSGA1_OCEIH Small ribosomal subunit biogenesis GTPase
RsgA 1 OS=Oceanobacillus iheyensis (strain DSM 14371 / CIP
107618 / JCM 11309 / KCTC 3954 / HTE831) OX=221109 GN=rsgA1
PE=3 SV=1
Length=351
Score = 37.7 bits (86), Expect = 0.35, Method: Composition-based stats.
Identities = 11/46 (24%), Positives = 21/46 (46%), Gaps = 8/46 (17%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRD 527
++LIG G++ L L+ ++ + T S R+ + GR
Sbjct 196 VVLIGSSGAGKSTLINALLTEKVLK--------TGSVREDDKRGRH 233
>sp|Q8VHK1|CSKI2_MOUSE Caskin-2 OS=Mus musculus OX=10090 GN=Caskin2
PE=1 SV=3
Length=1201
Score = 38.1 bits (87), Expect = 0.35, Method: Composition-based stats.
Identities = 37/200 (19%), Positives = 69/200 (35%), Gaps = 35/200 (18%)
Query 218 QALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIV--RIEKARDIPLGATVRNEM 275
Q LL +H VA E + + D + + V ++ KA
Sbjct 165 QLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLKA------------- 211
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEI---NGIEI--RGKDVNEVFDLLSDMHGTLTF 330
+ I+R K G A L+ EV+ + G+++ R D+++ F
Sbjct 212 -GIEINRQTKTGTALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIVNQ------F 264
Query 331 VLIPSQQIKPPPAKETV--IHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPN 388
+ + +E + V+A D+ DP L+ + GD++ V+ Q
Sbjct 265 TTSQASREIKQLLREASGILKVRALKDFWNLHDP------TALNVRAGDVITVLEQHPDG 318
Query 389 WWQAYREGDEDNQPLAGLVP 408
W+ + + G P
Sbjct 319 RWKGHIHESQRGTDRVGYFP 338
>sp|Q3Z542|TAUB_SHISS Taurine import ATP-binding protein TauB
OS=Shigella sonnei (strain Ss046) OX=300269 GN=tauB PE=3 SV=1
Length=255
Score = 37.3 bits (85), Expect = 0.35, Method: Composition-based stats.
Identities = 18/133 (14%), Positives = 40/133 (30%), Gaps = 22/133 (17%)
Query 464 LTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV 523
E+++L ++++GP CG+ L + + S R
Sbjct 15 PALEDINL---TLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSIQLAGKRIEGPGAE 71
Query 524 AGRDYHFVSRQAFEADIAAGKFIEHGEFEKNL-YGTSIDSVRQVINSGKICLLSLRTQSL 582
G F+ + + N+ +G + + ++ L + Q L
Sbjct 72 RGV--------VFQ----NEGLLPWRNVQDNVAFGLQLAGIEKMQR------LEIAHQML 113
Query 583 KTLRNSDLKPYII 595
K + + I
Sbjct 114 KKVGLEGAEKRYI 126
>sp|Q47538|TAUB_ECOLI Taurine import ATP-binding protein TauB
OS=Escherichia coli (strain K12) OX=83333 GN=tauB PE=2 SV=1
Length=255
Score = 37.3 bits (85), Expect = 0.35, Method: Composition-based stats.
Identities = 18/133 (14%), Positives = 40/133 (30%), Gaps = 22/133 (17%)
Query 464 LTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV 523
E+++L ++++GP CG+ L + + S R
Sbjct 15 PALEDINL---TLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSIQLAGKRIEGPGAE 71
Query 524 AGRDYHFVSRQAFEADIAAGKFIEHGEFEKNL-YGTSIDSVRQVINSGKICLLSLRTQSL 582
G F+ + + N+ +G + + ++ L + Q L
Sbjct 72 RGV--------VFQ----NEGLLPWRNVQDNVAFGLQLAGIEKMQR------LEIAHQML 113
Query 583 KTLRNSDLKPYII 595
K + + I
Sbjct 114 KKVGLEGAEKRYI 126
>sp|A2RAF6|LONP2_ASPNC Lon protease homolog 2, peroxisomal OS=Aspergillus
niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC
A1513) OX=425011 GN=An18g02980 PE=3 SV=1
Length=929
Score = 38.1 bits (87), Expect = 0.35, Method: Composition-based stats.
Identities = 18/137 (13%), Positives = 47/137 (34%), Gaps = 2/137 (1%)
Query 392 AYREGDEDNQPLAGLVPGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYN 451
A ++ D+D+ L + K + ++ +++ E+ + + +
Sbjct 392 ARKQLDDDHYGLEKI--KKRLLEYLAVLRLKQSTNRDVERQIESLSKELEASDGGDLEKE 449
Query 452 ANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAV 511
+ D + T M + ++ ++L+GP G+ L + + + +F
Sbjct 450 VPVLSETDRVAVETKLHMLKTRRMGDKSPILLLVGPPGVGKTSLARSVASSLGRKFHRIS 509
Query 512 PHTTRSRRDQEVAGRDY 528
R + R Y
Sbjct 510 LGGVRDEAEIRGHRRTY 526
>sp|Q9WVE8|PACN2_MOUSE Protein kinase C and casein kinase substrate
in neurons protein 2 OS=Mus musculus OX=10090 GN=Pacsin2
PE=1 SV=1
Length=486
Score = 37.7 bits (86), Expect = 0.36, Method: Composition-based stats.
Identities = 20/79 (25%), Positives = 30/79 (38%), Gaps = 11/79 (14%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
S T + V+A +DY+ + LSF+ GD L I ED Q +
Sbjct 416 SNPFDEDTTSGTEVRVRALYDYEGQEHDE-------LSFKAGDELTKIEDEDE---QGWC 465
Query 395 EGDEDNQPLAGLVPGKSFQ 413
+G + GL P +
Sbjct 466 KGR-LDSGQVGLYPANYVE 483
>sp|B0BNA1|SH3Y1_RAT SH3 domain-containing YSC84-like protein
1 OS=Rattus norvegicus OX=10116 GN=Sh3yl1 PE=2 SV=1
Length=340
Score = 37.3 bits (85), Expect = 0.36, Method: Composition-based stats.
Identities = 19/80 (24%), Positives = 29/80 (36%), Gaps = 15/80 (19%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPN--WWQA 392
S + + I V A + ++ L+FQ GD + VIS+ D N WW+
Sbjct 271 SSYHEKTGSLSQPIEVTALYSFEGQQPGD-------LNFQAGDRIIVISKTDSNFDWWEG 323
Query 393 YREGDEDNQPLAGLVPGKSF 412
G G+ P
Sbjct 324 KLRGQT------GIFPANYV 337
>sp|P72335|NODI_RHIS3 Nod factor export ATP-binding protein I
OS=Rhizobium sp. (strain N33) OX=103798 GN=nodI PE=3 SV=1
Length=304
Score = 37.3 bits (85), Expect = 0.36, Method: Composition-based stats.
Identities = 18/88 (20%), Positives = 32/88 (36%), Gaps = 10/88 (11%)
Query 484 LIGPQNCGQNELRQRLMN-KEKDRFASAV---PHTTRSRRDQEVAGRDYHFVSRQAFEAD 539
L+GP G++ + + L+ D V P RSR ++ G F+
Sbjct 36 LLGPNGAGKSTIARMLLGMTVPDAGKITVLGEPVGARSRLARKSIGV------VPQFDNL 89
Query 540 IAAGKFIEHGEFEKNLYGTSIDSVRQVI 567
E+ +G S +++VI
Sbjct 90 DQEFTVRENLLVFGRYFGMSTRKIKEVI 117
>sp|O43166|SI1L1_HUMAN Signal-induced proliferation-associated
1-like protein 1 OS=Homo sapiens OX=9606 GN=SIPA1L1 PE=1 SV=4
Length=1804
Score = 38.1 bits (87), Expect = 0.36, Method: Composition-based stats.
Identities = 22/118 (19%), Positives = 45/118 (38%), Gaps = 11/118 (9%)
Query 252 ETVKIVRIEKARDIPLGATVRNEMDSV---------IISRIVKGGAAEKSGLLHEGDEVL 302
E VK ++ + T+R I++ + G A ++G L +G ++
Sbjct 937 EIVKRLQFVSKGCESVEMTLRRNGLGQLGFHVNYEGIVADVEPYGYAWQAG-LRQGSRLV 995
Query 303 EINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSD 360
EI + + ++ DLL T+ V+IP P + + +Y ++
Sbjct 996 EICKVAVATLSHEQMIDLLR-TSVTVKVVIIPPHDDCTPRRSCSETYRMPVMEYKMNE 1052
>sp|P97814|PPIP1_MOUSE Proline-serine-threonine phosphatase-interacting
protein 1 OS=Mus musculus OX=10090 GN=Pstpip1 PE=1
SV=1
Length=415
Score = 37.7 bits (86), Expect = 0.36, Method: Composition-based stats.
Identities = 18/64 (28%), Positives = 25/64 (39%), Gaps = 13/64 (20%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
+A +DY + L GDIL VI + + WW R G G VPG
Sbjct 364 RALYDYTAQNSDE-------LDISAGDILAVILEGEDGWWTVERNG------QRGFVPGS 410
Query 411 SFQQ 414
++
Sbjct 411 YLEK 414
>sp|C1CSX0|DER_STRZT GTPase Der OS=Streptococcus pneumoniae (strain
Taiwan19F-14) OX=487213 GN=der PE=3 SV=1
Length=436
Score = 37.7 bits (86), Expect = 0.36, Method: Composition-based stats.
Identities = 22/88 (25%), Positives = 35/88 (40%), Gaps = 14/88 (16%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ--AFEADIA 541
LIG N G++ L ++ +++ AS V TTR D HF F I
Sbjct 179 LIGRPNVGKSSLINAILGEDR-VIASPVAGTTR-------DAIDTHFTDTDGQEF-TMID 229
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINS 569
+ G+ +N T SV + + +
Sbjct 230 TAGMRKSGKVYEN---TEKYSVMRAMRA 254
>sp|C1CM45|DER_STRZP GTPase Der OS=Streptococcus pneumoniae (strain
P1031) OX=488223 GN=der PE=3 SV=1
Length=436
Score = 37.7 bits (86), Expect = 0.36, Method: Composition-based stats.
Identities = 22/88 (25%), Positives = 35/88 (40%), Gaps = 14/88 (16%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ--AFEADIA 541
LIG N G++ L ++ +++ AS V TTR D HF F I
Sbjct 179 LIGRPNVGKSSLINAILGEDR-VIASPVAGTTR-------DAIDTHFTDTDGQEF-TMID 229
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINS 569
+ G+ +N T SV + + +
Sbjct 230 TAGMRKSGKVYEN---TEKYSVMRAMRA 254
>sp|C1CFT0|DER_STRZJ GTPase Der OS=Streptococcus pneumoniae (strain
JJA) OX=488222 GN=der PE=3 SV=1
Length=436
Score = 37.7 bits (86), Expect = 0.36, Method: Composition-based stats.
Identities = 22/88 (25%), Positives = 35/88 (40%), Gaps = 14/88 (16%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ--AFEADIA 541
LIG N G++ L ++ +++ AS V TTR D HF F I
Sbjct 179 LIGRPNVGKSSLINAILGEDR-VIASPVAGTTR-------DAIDTHFTDTDGQEF-TMID 229
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINS 569
+ G+ +N T SV + + +
Sbjct 230 TAGMRKSGKVYEN---TEKYSVMRAMRA 254
>sp|P64063|DER_STRR6 GTPase Der OS=Streptococcus pneumoniae (strain
ATCC BAA-255 / R6) OX=171101 GN=der PE=3 SV=1
Length=436
Score = 37.7 bits (86), Expect = 0.36, Method: Composition-based stats.
Identities = 22/88 (25%), Positives = 35/88 (40%), Gaps = 14/88 (16%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ--AFEADIA 541
LIG N G++ L ++ +++ AS V TTR D HF F I
Sbjct 179 LIGRPNVGKSSLINAILGEDR-VIASPVAGTTR-------DAIDTHFTDTDGQEF-TMID 229
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINS 569
+ G+ +N T SV + + +
Sbjct 230 TAGMRKSGKVYEN---TEKYSVMRAMRA 254
>sp|B2IRW4|DER_STRPS GTPase Der OS=Streptococcus pneumoniae (strain
CGSP14) OX=516950 GN=der PE=3 SV=1
Length=436
Score = 37.7 bits (86), Expect = 0.36, Method: Composition-based stats.
Identities = 22/88 (25%), Positives = 35/88 (40%), Gaps = 14/88 (16%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ--AFEADIA 541
LIG N G++ L ++ +++ AS V TTR D HF F I
Sbjct 179 LIGRPNVGKSSLINAILGEDR-VIASPVAGTTR-------DAIDTHFTDTDGQEF-TMID 229
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINS 569
+ G+ +N T SV + + +
Sbjct 230 TAGMRKSGKVYEN---TEKYSVMRAMRA 254
>sp|P64062|DER_STRPN GTPase Der OS=Streptococcus pneumoniae serotype
4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=der PE=3
SV=1
Length=436
Score = 37.7 bits (86), Expect = 0.36, Method: Composition-based stats.
Identities = 22/88 (25%), Positives = 35/88 (40%), Gaps = 14/88 (16%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ--AFEADIA 541
LIG N G++ L ++ +++ AS V TTR D HF F I
Sbjct 179 LIGRPNVGKSSLINAILGEDR-VIASPVAGTTR-------DAIDTHFTDTDGQEF-TMID 229
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINS 569
+ G+ +N T SV + + +
Sbjct 230 TAGMRKSGKVYEN---TEKYSVMRAMRA 254
>sp|B8ZMH4|DER_STRPJ GTPase Der OS=Streptococcus pneumoniae (strain
ATCC 700669 / Spain 23F-1) OX=561276 GN=der PE=3 SV=1
Length=436
Score = 37.7 bits (86), Expect = 0.36, Method: Composition-based stats.
Identities = 22/88 (25%), Positives = 35/88 (40%), Gaps = 14/88 (16%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ--AFEADIA 541
LIG N G++ L ++ +++ AS V TTR D HF F I
Sbjct 179 LIGRPNVGKSSLINAILGEDR-VIASPVAGTTR-------DAIDTHFTDTDGQEF-TMID 229
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINS 569
+ G+ +N T SV + + +
Sbjct 230 TAGMRKSGKVYEN---TEKYSVMRAMRA 254
>sp|B1I766|DER_STRPI GTPase Der OS=Streptococcus pneumoniae (strain
Hungary19A-6) OX=487214 GN=der PE=3 SV=1
Length=436
Score = 37.7 bits (86), Expect = 0.36, Method: Composition-based stats.
Identities = 22/88 (25%), Positives = 35/88 (40%), Gaps = 14/88 (16%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ--AFEADIA 541
LIG N G++ L ++ +++ AS V TTR D HF F I
Sbjct 179 LIGRPNVGKSSLINAILGEDR-VIASPVAGTTR-------DAIDTHFTDTDGQEF-TMID 229
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINS 569
+ G+ +N T SV + + +
Sbjct 230 TAGMRKSGKVYEN---TEKYSVMRAMRA 254
>sp|C1C8U6|DER_STRP7 GTPase Der OS=Streptococcus pneumoniae (strain
70585) OX=488221 GN=der PE=3 SV=1
Length=436
Score = 37.7 bits (86), Expect = 0.36, Method: Composition-based stats.
Identities = 22/88 (25%), Positives = 35/88 (40%), Gaps = 14/88 (16%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ--AFEADIA 541
LIG N G++ L ++ +++ AS V TTR D HF F I
Sbjct 179 LIGRPNVGKSSLINAILGEDR-VIASPVAGTTR-------DAIDTHFTDTDGQEF-TMID 229
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINS 569
+ G+ +N T SV + + +
Sbjct 230 TAGMRKSGKVYEN---TEKYSVMRAMRA 254
>sp|B5E756|DER_STRP4 GTPase Der OS=Streptococcus pneumoniae serotype
19F (strain G54) OX=512566 GN=der PE=3 SV=1
Length=436
Score = 37.7 bits (86), Expect = 0.36, Method: Composition-based stats.
Identities = 22/88 (25%), Positives = 35/88 (40%), Gaps = 14/88 (16%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ--AFEADIA 541
LIG N G++ L ++ +++ AS V TTR D HF F I
Sbjct 179 LIGRPNVGKSSLINAILGEDR-VIASPVAGTTR-------DAIDTHFTDTDGQEF-TMID 229
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINS 569
+ G+ +N T SV + + +
Sbjct 230 TAGMRKSGKVYEN---TEKYSVMRAMRA 254
>sp|Q04J64|DER_STRP2 GTPase Der OS=Streptococcus pneumoniae serotype
2 (strain D39 / NCTC 7466) OX=373153 GN=der PE=3 SV=1
Length=436
Score = 37.7 bits (86), Expect = 0.36, Method: Composition-based stats.
Identities = 22/88 (25%), Positives = 35/88 (40%), Gaps = 14/88 (16%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQ--AFEADIA 541
LIG N G++ L ++ +++ AS V TTR D HF F I
Sbjct 179 LIGRPNVGKSSLINAILGEDR-VIASPVAGTTR-------DAIDTHFTDTDGQEF-TMID 229
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINS 569
+ G+ +N T SV + + +
Sbjct 230 TAGMRKSGKVYEN---TEKYSVMRAMRA 254
>sp|Q9QY17|PACN2_RAT Protein kinase C and casein kinase substrate
in neurons 2 protein OS=Rattus norvegicus OX=10116 GN=Pacsin2
PE=1 SV=2
Length=488
Score = 37.7 bits (86), Expect = 0.36, Method: Composition-based stats.
Identities = 20/79 (25%), Positives = 30/79 (38%), Gaps = 11/79 (14%)
Query 335 SQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYR 394
S T + V+A +DY+ + LSF+ GD L I ED Q +
Sbjct 418 SNPFDEDTTSGTEVRVRALYDYEGQEHDE-------LSFKAGDELTKIEDEDE---QGWC 467
Query 395 EGDEDNQPLAGLVPGKSFQ 413
+G + GL P +
Sbjct 468 KGR-LDSGQVGLYPANYVE 485
>sp|Q9NQ75|CASS4_HUMAN Cas scaffolding protein family member 4
OS=Homo sapiens OX=9606 GN=CASS4 PE=1 SV=2
Length=786
Score = 37.7 bits (86), Expect = 0.36, Method: Composition-based stats.
Identities = 18/66 (27%), Positives = 25/66 (38%), Gaps = 16/66 (24%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDP---NWWQAYREGDEDNQPLAGLV 407
+A +D P L+F +GDIL ++ Q P WW+ G GL
Sbjct 17 RALYD-------NCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHG------RQGLA 63
Query 408 PGKSFQ 413
P Q
Sbjct 64 PANRLQ 69
>sp|C6HFQ7|SHO1_AJECH High osmolarity signaling protein SHO1 OS=Ajellomyces
capsulatus (strain H143) OX=544712 GN=SHO1 PE=3
SV=1
Length=325
Score = 37.3 bits (85), Expect = 0.37, Method: Composition-based stats.
Identities = 16/62 (26%), Positives = 23/62 (37%), Gaps = 11/62 (18%)
Query 351 KAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK 410
KA + Y+ + D +SF K +IL V WWQA + G+ P
Sbjct 272 KAIYSYEANPDDA-----NEISFSKHEILDVSDVS-GRWWQAKK-----ASGETGIAPSN 320
Query 411 SF 412
Sbjct 321 YL 322
>sp|Q9JLQ0|CD2AP_MOUSE CD2-associated protein OS=Mus musculus
OX=10090 GN=Cd2ap PE=1 SV=3
Length=637
Score = 37.7 bits (86), Expect = 0.37, Method: Composition-based stats.
Identities = 20/83 (24%), Positives = 28/83 (34%), Gaps = 13/83 (16%)
Query 332 LIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQ 391
+ P Q K K K FDY P + E L GD++ VI + + WW
Sbjct 95 IQPHPQTKAIKKKTKKRQCKVLFDYSPQN-------EDELELIVGDVIDVIEEVEEGWWS 147
Query 392 AYREGDEDNQPLAGLVPGKSFQQ 414
GL P ++
Sbjct 148 G------TLNNKLGLFPSNFVKE 164
Score = 36.6 bits (83), Expect = 0.80, Method: Composition-based stats.
Identities = 16/58 (28%), Positives = 27/58 (47%), Gaps = 9/58 (16%)
Query 349 HVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ--EDPNWWQAYREGDEDNQPLA 404
+ + F PY E L+F++G+I+H+IS+ + WW+ G E P
Sbjct 273 YCRTLF-------PYTGTNEDELTFREGEIIHLISKETGEAGWWKGELNGKEGVFPDN 323
>sp|Q9TU19|NPHP1_CANLF Nephrocystin-1 (Fragment) OS=Canis lupus
familiaris OX=9615 GN=NPHP1 PE=1 SV=1
Length=565
Score = 37.7 bits (86), Expect = 0.37, Method: Composition-based stats.
Identities = 13/53 (25%), Positives = 25/53 (47%), Gaps = 6/53 (11%)
Query 362 PYVPCRELG-LSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQ 413
++ G L+F+K +IL +I ++ WW A + + GL+P +
Sbjct 49 GDFTAQQAGDLTFKKREILLIIEKKPDGWWIAK-----NAKGNKGLIPRTYVE 96
>sp|Q93D97|Y1934_STRMU Putative ABC transporter ATP-binding protein
SMU_1934c OS=Streptococcus mutans serotype c (strain ATCC
700610 / UA159) OX=210007 GN=sdcBA PE=3 SV=1
Length=558
Score = 37.7 bits (86), Expect = 0.37, Method: Composition-based stats.
Identities = 10/52 (19%), Positives = 24/52 (46%), Gaps = 3/52 (6%)
Query 457 DYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFA 508
YD + T +E++L + + +++IGP G++ + L + +
Sbjct 13 KYDAQAEPTLKEITLSIEKGEK---VLIIGPSGSGKSTIGHCLNGIIPNIYK 61
>sp|Q8R1B0|STAC2_MOUSE SH3 and cysteine-rich domain-containing
protein 2 OS=Mus musculus OX=10090 GN=Stac2 PE=1 SV=1
Length=408
Score = 37.7 bits (86), Expect = 0.37, Method: Composition-based stats.
Identities = 33/168 (20%), Positives = 60/168 (36%), Gaps = 33/168 (20%)
Query 295 LHEGDEVLEINGIEIRGKDV---NEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETV---- 347
L E DE+ E IR + + VF ++ G+ P QQ P ++ V
Sbjct 233 LSERDELTEDGEGSIRSSEEGPGDSVFTAPAESEGSGPEEKSPGQQPPKLPLRKDVGPMY 292
Query 348 IHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLV 407
+V A + + P ++ L+ Q GD + ++ + +WW+ + GD G
Sbjct 293 SYV-ALYKFLPQENND-------LALQPGDRIMLVDDSNEDWWKG-KIGD-----RVGFF 338
Query 408 PGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKN 455
P Q+ R P ++ C + K + +
Sbjct 339 PANFVQRVR------------PGENVWRCCQPFSGNKEQGYMSLKENQ 374
>sp|O95786|RIGI_HUMAN Antiviral innate immune response receptor
RIG-I OS=Homo sapiens OX=9606 GN=RIGI PE=1 SV=2
Length=925
Score = 37.7 bits (86), Expect = 0.38, Method: Composition-based stats.
Identities = 23/131 (18%), Positives = 43/131 (33%), Gaps = 26/131 (20%)
Query 475 PANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSR- 533
PA + + I+ P CG+ + + +F Q G+ F ++
Sbjct 253 PAMKGKNTIICAPTGCGKTFVSLLICEHHLKKF------------PQGQKGKVVFFANQI 300
Query 534 QAFEADIAAGKFIEHGEFEKNLYGTSID-------SVRQVINSGKICLLSLRTQS-LKTL 585
+E F ++ E T I V Q++ + I +L Q + L
Sbjct 301 PVYEQ--QKSVFSKYFERHG-YRVTGISGATAENVPVEQIVENNDIIIL--TPQILVNNL 355
Query 586 RNSDLKPYIIF 596
+ + IF
Sbjct 356 KKGTIPSLSIF 366
>sp|Q9JIY5|HTRA2_MOUSE Serine protease HTRA2, mitochondrial OS=Mus
musculus OX=10090 GN=Htra2 PE=1 SV=2
Length=458
Score = 37.7 bits (86), Expect = 0.38, Method: Composition-based stats.
Identities = 14/71 (20%), Positives = 29/71 (41%), Gaps = 7/71 (10%)
Query 276 DSVIISRIVKGGAAEKSGLLHEGDEVLEI------NGIEIRGKDVNEVFDLLSDMHGTLT 329
V+I +++ G A ++G L GD +L I N ++ + + G+ T
Sbjct 389 HGVLIHKVILGSPAHRAG-LRPGDVILAIGEKLAQNAEDVYEAVRTQSQLAVRIRRGSET 447
Query 330 FVLIPSQQIKP 340
L + ++
Sbjct 448 LTLYVTPEVTE 458
>sp|F4JWM0|DSC2_ARATH Disease resistance-like protein DSC2 OS=Arabidopsis
thaliana OX=3702 GN=DSC2 PE=1 SV=1
Length=1210
Score = 38.1 bits (87), Expect = 0.38, Method: Composition-based stats.
Identities = 9/41 (22%), Positives = 21/41 (51%), Gaps = 0/41 (0%)
Query 470 SLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASA 510
SL ++ R I ++GP G+ + + L ++ ++F +
Sbjct 246 SLLCLESSDVRMIGILGPPGIGKTTIARVLYDQISEKFQFS 286
>sp|C6C0G0|DER_MARSD GTPase Der OS=Maridesulfovibrio salexigens
(strain ATCC 14822 / DSM 2638 / NCIMB 8403 / VKM B-1763) OX=526222
GN=der PE=3 SV=1
Length=450
Score = 37.7 bits (86), Expect = 0.38, Method: Composition-based stats.
Identities = 24/101 (24%), Positives = 38/101 (38%), Gaps = 13/101 (13%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEA 538
I LIG N G++ L RL+ K++ +P TR R + G Y A
Sbjct 4 TIALIGRPNVGKSTLFNRLLRKKR-AITHDMPGITRDRIYAEGNYNGVHY---------A 53
Query 539 DIAAGKFI-EHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
I G + E + G + R+ I + +L +
Sbjct 54 LIDTGGLVMESDNNSEEFQGDIFEQAREAIEEAQALILVVD 94
>sp|Q8TC17|GRAPL_HUMAN GRB2-related adapter protein-like OS=Homo
sapiens OX=9606 GN=GRAPL PE=1 SV=3
Length=118
Score = 35.4 bits (80), Expect = 0.38, Method: Composition-based stats.
Identities = 15/63 (24%), Positives = 29/63 (46%), Gaps = 14/63 (22%)
Query 352 AHFDYDPSDDPYVPCRELGLSFQKGDILHVIS-QEDPNWWQAYREGDEDNQPLAGLVPGK 410
A + + ++ L+F KGD L +++ ++D NW++A G E G +P
Sbjct 5 ALYSFQATESDE-------LAFNKGDTLKILNMEDDQNWYKAELRGVE------GFIPKN 51
Query 411 SFQ 413
+
Sbjct 52 YIR 54
>sp|F6U5F9|INTU_XENTR Protein inturned OS=Xenopus tropicalis OX=8364
GN=intu PE=3 SV=1
Length=953
Score = 37.7 bits (86), Expect = 0.38, Method: Composition-based stats.
Identities = 13/81 (16%), Positives = 34/81 (42%), Gaps = 6/81 (7%)
Query 252 ETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
K + + +++ + + +++ + G A + G + GD ++ +N +E+
Sbjct 192 RNSKRIERQGSQEASQRLS---NQEKLVVHGFIPGSPAIRCGQILIGDTLVAVNDVEV-- 246
Query 312 KDVNEVFDLLSDMHGTLTFVL 332
V + +LS + G L
Sbjct 247 -HVENIERVLSCIPGPTQVKL 266
>sp|A6KWL7|MIAA1_PHOV8 tRNA dimethylallyltransferase 1 OS=Phocaeicola
vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / CCUG
4940 / NBRC 14291 / NCTC 11154) OX=435590 GN=miaA1 PE=3
SV=1
Length=300
Score = 37.3 bits (85), Expect = 0.39, Method: Composition-based stats.
Identities = 14/59 (24%), Positives = 24/59 (41%), Gaps = 8/59 (14%)
Query 481 PIILIGPQNCGQNELRQRLMNKEKDRFASAVPHT--------TRSRRDQEVAGRDYHFV 531
I+LIGP G+ EL + + SA T + +++A ++FV
Sbjct 5 LIVLIGPTGVGKTELSLSIAEHFRTSIVSADSRQLYADLKIGTAAPTPEQLARVPHYFV 63
>sp|Q0IIR9|KTNA1_XENTR Katanin p60 ATPase-containing subunit A1
OS=Xenopus tropicalis OX=8364 GN=katna1 PE=2 SV=1
Length=492
Score = 37.7 bits (86), Expect = 0.39, Method: Composition-based stats.
Identities = 23/138 (17%), Positives = 48/138 (35%), Gaps = 21/138 (15%)
Query 408 PGKSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLYNANKNDDYDN------E 461
P ++ +++ +K E++K + K + K L A + D +
Sbjct 151 PVRAREKKDTFLKVKDEKNKSSVDVSETEVKKFDGTGYDKDLIEALERDIISQNPNIRWD 210
Query 462 EILTYEE---------MSLYHQPANRK------RPIILIGPQNCGQNELRQRLMNKEKDR 506
+I EE + P K + ++++GP G+ L + + + K
Sbjct 211 DIADLEEAKKLLKEAVVLPMWMPEFFKGIRRPWKGVLMVGPPGTGKTLLAKAVATECKTT 270
Query 507 FASAVPHTTRSRRDQEVA 524
F + T S+ E
Sbjct 271 FFNISSSTLTSKYRGESE 288
>sp|Q5RAQ2|SH3Y1_PONAB SH3 domain-containing YSC84-like protein
1 OS=Pongo abelii OX=9601 GN=SH3YL1 PE=2 SV=1
Length=342
Score = 37.3 bits (85), Expect = 0.39, Method: Composition-based stats.
Identities = 17/70 (24%), Positives = 26/70 (37%), Gaps = 15/70 (21%)
Query 345 ETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQED--PNWWQAYREGDEDNQP 402
I V A + ++ L+FQ GD + VIS+ D +WW+ G
Sbjct 283 NQPIEVTALYSFEGQQPGD-------LNFQAGDRITVISKTDSHFDWWEGKLRGQT---- 331
Query 403 LAGLVPGKSF 412
G+ P
Sbjct 332 --GIFPANYV 339
>sp|Q96HL8|SH3Y1_HUMAN SH3 domain-containing YSC84-like protein
1 OS=Homo sapiens OX=9606 GN=SH3YL1 PE=1 SV=1
Length=342
Score = 37.3 bits (85), Expect = 0.39, Method: Composition-based stats.
Identities = 17/70 (24%), Positives = 26/70 (37%), Gaps = 15/70 (21%)
Query 345 ETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQED--PNWWQAYREGDEDNQP 402
I V A + ++ L+FQ GD + VIS+ D +WW+ G
Sbjct 283 NQPIEVTALYSFEGQQPGD-------LNFQAGDRITVISKTDSHFDWWEGKLRGQT---- 331
Query 403 LAGLVPGKSF 412
G+ P
Sbjct 332 --GIFPANYV 339
>sp|Q83MA0|TAUB_SHIFL Taurine import ATP-binding protein TauB
OS=Shigella flexneri OX=623 GN=tauB PE=3 SV=1
Length=255
Score = 37.0 bits (84), Expect = 0.39, Method: Composition-based stats.
Identities = 18/133 (14%), Positives = 40/133 (30%), Gaps = 22/133 (17%)
Query 464 LTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEV 523
E+++L ++++GP CG+ L + + S R
Sbjct 15 PALEDINL---TLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSIQLAGKRIEGPGAE 71
Query 524 AGRDYHFVSRQAFEADIAAGKFIEHGEFEKNL-YGTSIDSVRQVINSGKICLLSLRTQSL 582
G F+ + + N+ +G + + ++ L + Q L
Sbjct 72 RGV--------VFQ----NEGLLPWRNVQDNVAFGLQLAGIEKMQR------LEIAHQML 113
Query 583 KTLRNSDLKPYII 595
K + + I
Sbjct 114 KKVGLEGAEKRYI 126
>sp|Q085U2|DER_SHEFN GTPase Der OS=Shewanella frigidimarina (strain
NCIMB 400) OX=318167 GN=der PE=3 SV=1
Length=488
Score = 37.7 bits (86), Expect = 0.39, Method: Composition-based stats.
Identities = 20/97 (21%), Positives = 35/97 (36%), Gaps = 12/97 (12%)
Query 484 LIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSR--RDQEVAGRDYHFVSRQAFEADIA 541
+IG N G++ L R++ +E+ P TTR GR+Y +
Sbjct 204 IIGKPNVGKSTLINRILGEER-VVVYDEPGTTRDSIYIPMSREGREYVLIDTAGVRRRSK 262
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLR 578
+ IE K ++ +V + LL +
Sbjct 263 VNEVIEKFSVIK-----TLKAVEDA----NVVLLVID 290
>sp|Q8FW07|UGPC_BRUSU sn-glycerol-3-phosphate import ATP-binding
protein UgpC OS=Brucella suis biovar 1 (strain 1330) OX=204722
GN=ugpC PE=3 SV=1
Length=351
Score = 37.3 bits (85), Expect = 0.39, Method: Composition-based stats.
Identities = 25/153 (16%), Positives = 45/153 (29%), Gaps = 60/153 (39%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++L+GP CG++ L + + E ++ T S ++ V + E DI
Sbjct 33 VVLVGPSGCGKSTLLRMIAGLE------SITSGTISIGERVVNNV-------EPAERDI- 78
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+N +VR+ + G
Sbjct 79 -------AMVFQNYALYPHMTVRENLAYG------------------------------- 100
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQN 634
L+ K PK E R I + + +E
Sbjct 101 ---LKNR-----KTPKEEIERRIAKAAKALEIE 125
>sp|Q578E9|UGPC_BRUAB sn-glycerol-3-phosphate import ATP-binding
protein UgpC OS=Brucella abortus biovar 1 (strain 9-941)
OX=262698 GN=ugpC PE=3 SV=1
Length=351
Score = 37.3 bits (85), Expect = 0.39, Method: Composition-based stats.
Identities = 25/153 (16%), Positives = 45/153 (29%), Gaps = 60/153 (39%)
Query 482 IILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFVSRQAFEADIA 541
++L+GP CG++ L + + E ++ T S ++ V + E DI
Sbjct 33 VVLVGPSGCGKSTLLRMIAGLE------SITSGTISIGERVVNNV-------EPAERDI- 78
Query 542 AGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPS 601
+N +VR+ + G
Sbjct 79 -------AMVFQNYALYPHMTVRENLAYG------------------------------- 100
Query 602 QERLRALLAKEGKNPKPEELREIIEKTREMEQN 634
L+ K PK E R I + + +E
Sbjct 101 ---LKNR-----KTPKEEIERRIAKAAKALEIE 125
>sp|Q46I43|RSGA_PROMT Small ribosomal subunit biogenesis GTPase
RsgA OS=Prochlorococcus marinus (strain NATL2A) OX=59920 GN=rsgA
PE=3 SV=1
Length=312
Score = 37.3 bits (85), Expect = 0.39, Method: Composition-based stats.
Identities = 6/24 (25%), Positives = 11/24 (46%), Gaps = 0/24 (0%)
Query 477 NRKRPIILIGPQNCGQNELRQRLM 500
+ + +L GP G+ L L+
Sbjct 178 RKTKLTVLAGPSGVGKTSLINHLI 201
>sp|A2BZC2|RSGA_PROM1 Small ribosomal subunit biogenesis GTPase
RsgA OS=Prochlorococcus marinus (strain NATL1A) OX=167555
GN=rsgA PE=3 SV=1
Length=312
Score = 37.3 bits (85), Expect = 0.39, Method: Composition-based stats.
Identities = 6/24 (25%), Positives = 11/24 (46%), Gaps = 0/24 (0%)
Query 477 NRKRPIILIGPQNCGQNELRQRLM 500
+ + +L GP G+ L L+
Sbjct 178 RKTKLTVLAGPSGVGKTSLINHLI 201
>sp|Q9P2F8|SI1L2_HUMAN Signal-induced proliferation-associated
1-like protein 2 OS=Homo sapiens OX=9606 GN=SIPA1L2 PE=1 SV=2
Length=1722
Score = 37.7 bits (86), Expect = 0.40, Method: Composition-based stats.
Identities = 22/111 (20%), Positives = 43/111 (39%), Gaps = 5/111 (5%)
Query 274 EMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 333
+ + ++ + G A K+G L +G ++EI + + ++ DLL T+ V+I
Sbjct 966 NFEGI-VADVEPFGFAWKAG-LRQGSRLVEICKVAVATLTHEQMIDLLR-TSVTVKVVII 1022
Query 334 PSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQ 384
P + + +Y D PC E F++ H +
Sbjct 1023 QPHDDGSPRRGCSELCRIPMVEY-KLDSEGTPC-EYKTPFRRNTTWHRVPT 1071
>sp|Q4WLG1|NM111_ASPFU Pro-apoptotic serine protease nma111 OS=Aspergillus
fumigatus (strain ATCC MYA-4609 / CBS 101355 /
FGSC A1100 / Af293) OX=330879 GN=nma111 PE=3 SV=1
Length=1028
Score = 37.7 bits (86), Expect = 0.40, Method: Composition-based stats.
Identities = 20/116 (17%), Positives = 47/116 (41%), Gaps = 5/116 (4%)
Query 235 EPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDSVIISRIVKGGAAEKSGL 294
EP+T + + + + + + + +E ++ I+ G A+ G
Sbjct 279 EPVTRGTIQTQWILKPFDECRRLGLTPEWEAAVRKASPHETSMLVAEIILPEGPAD--GK 336
Query 295 LHEGDEVLEINGIEIRG-KDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIH 349
L EGD +L++NG + ++++ D S + T+ ++ Q + +H
Sbjct 337 LEEGDVLLQVNGELLTQFIRLDDILD--SSVGKTVRLLVQRGGQNVEVECEVGDLH 390
>sp|Q8Z193|RSGA_SALTI Small ribosomal subunit biogenesis GTPase
RsgA OS=Salmonella typhi OX=90370 GN=rsgA PE=3 SV=2
Length=350
Score = 37.3 bits (85), Expect = 0.41, Method: Composition-based stats.
Identities = 13/57 (23%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ + + + V + + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQNEILTNDVSNVSGLGQHTTTAARLYHF 258
>sp|P9WNM9|EFGL_MYCTU Elongation factor G-like protein OS=Mycobacterium
tuberculosis (strain ATCC 25618 / H37Rv) OX=83332
GN=Rv0120c PE=1 SV=1
Length=714
Score = 37.7 bits (86), Expect = 0.41, Method: Composition-based stats.
Identities = 7/21 (33%), Positives = 13/21 (62%), Gaps = 0/21 (0%)
Query 480 RPIILIGPQNCGQNELRQRLM 500
R ++L+GP G+ L + L+
Sbjct 24 RNVVLVGPSGGGKTTLIEALL 44
>sp|Q8ZKB0|RSGA_SALTY Small ribosomal subunit biogenesis GTPase
RsgA OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC
700720) OX=99287 GN=rsgA PE=1 SV=2
Length=350
Score = 37.3 bits (85), Expect = 0.41, Method: Composition-based stats.
Identities = 13/57 (23%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ + + + V + + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQNEILTNDVSNVSGLGQHTTTAARLYHF 258
>sp|B4TSE3|RSGA_SALSV Small ribosomal subunit biogenesis GTPase
RsgA OS=Salmonella schwarzengrund (strain CVM19633) OX=439843
GN=rsgA PE=3 SV=1
Length=350
Score = 37.3 bits (85), Expect = 0.41, Method: Composition-based stats.
Identities = 13/57 (23%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ + + + V + + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQNEILTNDVSNVSGLGQHTTTAARLYHF 258
>sp|A9N420|RSGA_SALPB Small ribosomal subunit biogenesis GTPase
RsgA OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)
OX=1016998 GN=rsgA PE=3 SV=1
Length=350
Score = 37.3 bits (85), Expect = 0.41, Method: Composition-based stats.
Identities = 13/57 (23%), Positives = 23/57 (40%), Gaps = 0/57 (0%)
Query 474 QPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHF 530
+ A R I G G++ L L+ + + + V + + + A R YHF
Sbjct 202 EEALTGRISIFAGQSGVGKSSLLNALLGLQNEILTNDVSNVSGLGQHTTTAARLYHF 258
Lambda K H a alpha
0.317 0.135 0.359 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0413 0.140 1.90 42.6 43.6
Effective search space used: 74397480300
Database: uniprot_sprot.fasta
Posted date: Apr 3, 2024 12:05 PM
Number of letters in database: 206,678,396
Number of sequences in database: 571,282
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40