Contact Molecules for Homologous Proteins

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PID QueryLength Homolgous Sequence in PDB UniProt Query TITLE
2932749 515 12 P48551(INAR2_HUMAN) RecName: Full=Interferon alpha/beta receptor 2; Short=IFN-R-2; Short=IFN-alpha binding protein; Short=IFN-alpha/beta receptor 2;AltName: Full=Interferon alpha binding protein;AltName: Full=Type I interferon receptor 2;Flags: Precursor;
QUERYSEQ 
MLLSQNAFIFRSLNLVLMVYISLVFGISYDSPDYTDESCTFKISLRNFRSILSWELKNHSIVPTHYTLLYTIMSKPEDLKVVKNCANTTRSFCDLTDEWRSTHEAYVTVLEGFSGNTTLFSCSHNFWLAIDMSFEPPEFEIVGFTNHINV
MVKFPSIVEEELQFDLSLVIEEQSEGIVKKHKPEIKGNMSGNFTYIIDKLIPNTNYCVSVYLEHSDEQAVIKSPLKCTLLPPGQESESAESAKIGGIITVFLIALVLTSTIVTLKWIGYICLRNSLPKVLNFHNFLAWPFPNLPPLEAMD
MVEVIYINRKKKVWDYNYDDESDSDTEAAPRTSGGGYTMHGLTVRPLGQASATSTESQLIDPESEEEPDLPEVDVELPTMPKDSPQQLELLSGPCERRKSPLQDPFPEEDYSSTEGSGGRITFNVDLNSVFLRVLDDEDSDDLEAPLMLS
SHLEEMVDPEDPDNVQSNHLLASGEGTQPTFPSPSSEGLWSEDAPSDQSDTSESDVDLGDGYIMR
[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ] 
  [n]:site number of query sequence.  [a]:amino acid of query sequence.  [s]:predicted secondary structure.
  [e]:predicted exposed/buried.  [acc]:predicted relative accesssibility(%).  [pdb]:PDB code of homologous structure.
  [contact_mols]:predicted binding molecules  [observed aa]:Observed amino acids among homologous sequences.  [feature table]:UniProt Feature Table
  [variant]:UniProt Human Variant.
n a s e acc pdb contact_mols observed aa feature table variant
1M---- 
M
 SIGNAL DISORDER predicted by DISOPRED SIGNAL
2L---- 
L
 SIGNAL DISORDER predicted by DISOPRED SIGNAL
3L---- 
L
 SIGNAL DISORDER predicted by DISOPRED SIGNAL
4S---- 
S
 SIGNAL DISORDER predicted by DISOPRED SIGNAL
5Q---- 
Q
 SIGNAL DISORDER predicted by DISOPRED SIGNAL
6N---- 
NS
 SIGNAL DISORDER predicted by DISOPRED SIGNAL
7A---- 
AV
 SIGNAL DISORDER predicted by DISOPRED SIGNAL
8F---- 
SVF
 SIGNAL DISORDER predicted by DISOPRED SIGNAL F->S:(44.0 %):LB/B - dbSNP:rs2229207
9I---- 
AGI
 SIGNAL DISORDER predicted by DISOPRED SIGNAL
10F---- 
ILF
 SIGNAL DISORDER predicted by DISOPRED SIGNAL F->V:(0.0 %):LB/B - dbSNP:rs1051393
11R---- 
GLR
 SIGNAL DISORDER predicted by DISOPRED SIGNAL
12S---- 
SP
 SIGNAL DISORDER predicted by DISOPRED SIGNAL
13L---- 
L
 SIGNAL DISORDER predicted by DISOPRED SIGNAL
14N---- 
NC
 SIGNAL DISORDER predicted by DISOPRED SIGNAL
15L---- 
L
 SIGNAL DISORDER predicted by DISOPRED SIGNAL
16V---- 
VY
 SIGNAL DISORDER predicted by DISOPRED SIGNAL
17L---- 
PVL
 SIGNAL DISORDER predicted by DISOPRED SIGNAL
18M---- 
MS
 SIGNAL DISORDER predicted by DISOPRED SIGNAL
19V---- 
VA
 SIGNAL SIGNAL
20Y---- 
HSY
 SIGNAL SIGNAL
21I---- 
IL
 SIGNAL SIGNAL
22S---- 
SE
 SIGNAL SIGNAL
23L---- 
LT
 SIGNAL SIGNAL
24V---- 
VI
 SIGNAL SIGNAL
25F---- 
FT
 SIGNAL SIGNAL
26G---- 
GP
 SIGNAL SIGNAL
27I---- 
IS
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
28S e132.0 2hym_A 
SA
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
29Y e 90.9 2hym_A 
YF
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
30DSe 94.4 2hym_A 
DV
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
31SSe 57.0 2hym_A 
GSAV
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
32P e 79.8 2hym_A 
PLADEGIKRSTVCFHMNQY
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
33D e 76.5 2hym_A 
DVLAEGIKPRSTCFHMNQY
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
34Y e 74.3 2hym_A 
YL
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
35TTe 42.2 2hym_A 
SPT
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
36DTe 30.9 2hym_A 
D
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
37E e 36.7 2hym_A 
E
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular" E->Q:(0.0 %):LB/B - dbSNP:rs2010033
38S e 27.3 2hym_A 
SPH
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
39C b 2.0 2hym_A 
C
 DISULFID ECO:0000269|PubMed:20496919, ECO:0000269|PubMed:21819146, ECO:0000269|PubMed:21854986, ECO:0007744|PDB:1N6U, ECO:0007744|PDB:1N6V, ECO:0007744|PDB:2HYM, ECO:0007744|PDB:2KZ1, ECO:0007744|PDB:2LAG, ECO:0007744|PDB:3S9D, ECO:0007744|PDB:3SE3, ECO:0007744|PDB:3SE4" TOPO_DOM /note="Extracellular" DISULFID ECO:0000269|PubMed:20496919, ECO:0000269|PubMed:21819146, ECO:0000269|PubMed:21854986, ECO:0007744|PDB:1N6U, ECO:0007744|PDB:1N6V, ECO:0007744|PDB:2HYM, ECO:0007744|PDB:2KZ1, ECO:0007744|PDB:2LAG, ECO:0007744|PDB:3S9D, ECO:0007744|PDB:3SE3, ECO:0007744|PDB:3SE4" TOPO_DOM /note="Extracellular"
40TEe 72.7 2hym_A 
T
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
41FEb 6.2 2hym_A 
LIF
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
42KEe 58.0 2hym_A 
KN
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
43IEb 0.0 2hym_A 
IM
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
44SEe 32.8 2hym_A 
RTS
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
45LEb 6.2 2hym_A 
FIL
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
46RSe 57.7 2hym_A 
R
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
47NSe 42.4 2hym_A 
N
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
48FSb 16.3 2hym_A 
FS
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
49R e 54.2 2hym_A 
RQ
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
50SEb 2.3 2hym_A 
SL
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
51IEb 9.4 2hym_A 
IV
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
52LEb 0.0 2hym_A 
L
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
53SEe 39.8 2hym_A 
S
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
54WEb 3.6 2hym_A 
W
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
55EEe 54.8 2hym_A 
E
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
56L b 10.1 2hym_A 
L
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
57K e 45.8 2hym_A 
KE
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
58N e 25.5 2hym_A 
N
 CARBOHYD /note="N-linked (GlcNAc...) asparagine" TOPO_DOM /note="Extracellular" CARBOHYD /note="N-linked (GlcNAc...) asparagine" TOPO_DOM /note="Extracellular"
59HSe 63.4 2hym_A 
HKR
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
60SSe 71.9 2hym_A 
S
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
61I e 75.4 2hym_A 
IG
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
62V e 88.0 2hym_A 
VP
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
63P b 0.8 2hym_A 
P
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
64T e 61.7 2hym_A 
TA
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
65HEe 21.5 2hym_A 
HN
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
66YEb 10.0 2hym_A 
Y
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
67TEb 11.0 2hym_A 
T
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
68LEb 0.0 2hym_A 
L
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
69LEb 10.1 2hym_A 
WL
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
70YEb 3.9 2hym_A 
Y
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
71TEb 1.3 2hym_A hetero IFNA2_HUMAN Q86UP4_HUMAN IFNW1_HUMAN 
T
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
72IEe 32.2 2hym_A hetero IFNA2_HUMAN Q86UP4_HUMAN IFNW1_HUMAN 
IV
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
73MTe 66.7 2hym_A hetero IFNA2_HUMAN Q86UP4_HUMAN IFNW1_HUMAN 
M
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular" M->V:(0.0 %):LB/B - dbSNP:rs1428501
74STe 59.4 2hym_A hetero IFNA2_HUMAN Q86UP4_HUMAN IFNW1_HUMAN 
S
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
75K e 39.6 2hym_A hetero IFNA2_HUMAN Q86UP4_HUMAN IFNW1_HUMAN 
K
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
76PTe 69.0 2hym_A hetero IFNA2_HUMAN Q86UP4_HUMAN IFNW1_HUMAN 
PDR
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
77ETe 87.4 2hym_A hetero IFNA2_HUMAN Q86UP4_HUMAN IFNW1_HUMAN 
E
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
78D e 49.4 2hym_A hetero IFNA2_HUMAN 
DN
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
79L e 55.1 2hym_A hetero IFNA2_HUMAN 
LM
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
80KEe 50.5 2hym_A 
KT
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
81VEe 60.0 2hym_A 
VK
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
82V b 5.3 2hym_A 
V
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
83KSe 83.5 2hym_A 
K
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
84NSe 66.7 2hym_A 
ND
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
85CSb 0.0 2hym_A 
C
 DISULFID ECO:0000269|PubMed:20496919, ECO:0000269|PubMed:21819146, ECO:0000269|PubMed:21854986, ECO:0007744|PDB:1N6U, ECO:0007744|PDB:1N6V, ECO:0007744|PDB:2HYM, ECO:0007744|PDB:2KZ1, ECO:0007744|PDB:2LAG, ECO:0007744|PDB:3S9D, ECO:0007744|PDB:3SE3, ECO:0007744|PDB:3SE4" TOPO_DOM /note="Extracellular" DISULFID ECO:0000269|PubMed:20496919, ECO:0000269|PubMed:21819146, ECO:0000269|PubMed:21854986, ECO:0007744|PDB:1N6U, ECO:0007744|PDB:1N6V, ECO:0007744|PDB:2HYM, ECO:0007744|PDB:2KZ1, ECO:0007744|PDB:2LAG, ECO:0007744|PDB:3S9D, ECO:0007744|PDB:3SE3, ECO:0007744|PDB:3SE4" TOPO_DOM /note="Extracellular"
86ASb 13.4 2hym_A 
ISA
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
87NSe 81.2 2hym_A 
ND
 CARBOHYD /note="N-linked (GlcNAc...) asparagine" TOPO_DOM /note="Extracellular" CARBOHYD /note="N-linked (GlcNAc...) asparagine" TOPO_DOM /note="Extracellular"
88TBb 14.3 2hym_A 
TIV
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
89TSe 76.6 2hym_A 
T
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
90R e 56.5 2hym_A 
RK
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
91SSe 57.8 2hym_A 
S
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
92FEe 21.5 2hym_A 
FS
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
93CEb 0.0 2hym_A 
C
 DISULFID ECO:0000269|PubMed:20496919, ECO:0000269|PubMed:21819146, ECO:0000269|PubMed:21854986, ECO:0007744|PDB:1N6U, ECO:0007744|PDB:1N6V, ECO:0007744|PDB:2HYM, ECO:0007744|PDB:2KZ1, ECO:0007744|PDB:2LAG, ECO:0007744|PDB:3S9D, ECO:0007744|PDB:3SE3, ECO:0007744|PDB:3SE4" TOPO_DOM /note="Extracellular" DISULFID ECO:0000269|PubMed:20496919, ECO:0000269|PubMed:21819146, ECO:0000269|PubMed:21854986, ECO:0007744|PDB:1N6U, ECO:0007744|PDB:1N6V, ECO:0007744|PDB:2HYM, ECO:0007744|PDB:2KZ1, ECO:0007744|PDB:2LAG, ECO:0007744|PDB:3S9D, ECO:0007744|PDB:3SE3, ECO:0007744|PDB:3SE4" TOPO_DOM /note="Extracellular"
94DEe 37.7 2hym_A 
D
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
95L b 0.0 2hym_A 
LV
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
96TTe 29.9 2hym_A 
T
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
97DTe 55.6 2hym_A hetero IFNA2_HUMAN 
D
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
98ETe 40.7 2hym_A 
VKE
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
99W b 2.4 2hym_A 
W
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
100R e 71.9 2hym_A hetero IFNA2_HUMAN 
VLR
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
101S e 26.6 2hym_A hetero IFNA2_HUMAN 
NES
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
102TSe 23.4 2hym_A 
TGR
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
103HSe 91.6 2hym_A hetero IFNA2_HUMAN Q86UP4_HUMAN IFNW1_HUMAN 
TMH
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
104ESe 21.1 2hym_A hetero IFNA2_HUMAN Q86UP4_HUMAN 
ED
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
105A b 4.5 2hym_A hetero IFNA2_HUMAN metal CL 
MSA
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
106YEb 5.2 2hym_A 
Y
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
107VEe 22.0 2hym_A hetero IFNA2_HUMAN Q86UP4_HUMAN IFNW1_HUMAN 
VI
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
108TEb 0.0 2hym_A hetero IFNA2_HUMAN 
ATPS
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
109VEb 2.7 2hym_A hetero IFNA2_HUMAN IFNW1_HUMAN 
QIV
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
110LEb 0.0 2hym_A 
VL
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
111EEe 22.6 2hym_A 
VIE
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
112GEb 0.0 2hym_A 
GV
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
113FEb 18.7 2hym_A 
FHY
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
114SEb 10.9 2hym_A 
RS
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
115GTe 42.9 2hym_A 
GE
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
116NTe113.3 2hym_A 
ND
 CARBOHYD /note="N-linked (GlcNAc...) asparagine" TOPO_DOM /note="Extracellular" CARBOHYD /note="N-linked (GlcNAc...) asparagine" TOPO_DOM /note="Extracellular"
117TEe 77.9 2hym_A 
ALT
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
118TEe 55.2 2hym_A 
TKV
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
119LEe 25.8 2hym_A 
VL
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
120FEb 2.4 2hym_A 
VCF
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
121S e 34.4 2hym_A 
SRI
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
122C b 18.0 2hym_A 
C
 DISULFID ECO:0000269|PubMed:20496919, ECO:0000269|PubMed:21819146, ECO:0000269|PubMed:21854986, ECO:0007744|PDB:1N6U, ECO:0007744|PDB:1N6V, ECO:0007744|PDB:2HYM, ECO:0007744|PDB:2KZ1, ECO:0007744|PDB:2LAG, ECO:0007744|PDB:3S9D, ECO:0007744|PDB:3SE3, ECO:0007744|PDB:3SE4" TOPO_DOM /note="Extracellular" DISULFID ECO:0000269|PubMed:20496919, ECO:0000269|PubMed:21819146, ECO:0000269|PubMed:21854986, ECO:0007744|PDB:1N6U, ECO:0007744|PDB:1N6V, ECO:0007744|PDB:2HYM, ECO:0007744|PDB:2KZ1, ECO:0007744|PDB:2LAG, ECO:0007744|PDB:3S9D, ECO:0007744|PDB:3SE3, ECO:0007744|PDB:3SE4" TOPO_DOM /note="Extracellular"
123SEe 51.6 2hym_A hetero IFNA2_HUMAN Q86UP4_HUMAN IFNW1_HUMAN 
SM
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
124HEe 46.1 2hym_A hetero IFNA2_HUMAN 
GHLADEIKPRSTVCFMNQY
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
125NEe 62.4 2hym_A hetero IFNA2_HUMAN Q86UP4_HUMAN IFNW1_HUMAN metal CL 
SDN
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
126FEb 14.8 2hym_A metal CL 
FY
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
127W e 31.9 2hym_A hetero IFNA2_HUMAN Q86UP4_HUMAN IFNW1_HUMAN metal CL 
FIW
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
128LTb 4.5 2hym_A 
LV
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
129ATb 9.8 2hym_A hetero IFNA2_HUMAN IFNW1_HUMAN 
APV
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
130ITe 68.4 2hym_A hetero IFNA2_HUMAN Q86UP4_HUMAN IFNW1_HUMAN 
AIPS
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
131D e 25.9 2hym_A 
DN
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
132M b 2.4 2hym_A 
KAM
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
133SEb 2.3 2hym_A 
PS
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
134FEb 1.9 2hym_A 
LF
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
135E e 42.7 2hym_A 
ED
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
136P e 53.5 2hym_A 
P
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
137PSb 5.4 2hym_A 
P
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
138EEe 54.8 2hym_A 
EK
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular" E->V:(0.0 %):US -
139FEb 5.7 2hym_A 
F
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
140EEe 41.2 2hym_A 
E
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
141IEb 5.3 2hym_A 
I
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
142VEe 67.3 2hym_A 
V
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
143GEb 17.9 2hym_A 
GD
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
144F e 35.9 2hym_A 
F
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
145TSe 53.2 2hym_A 
T
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
146NSe 59.4 2hym_A 
ND
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
147HEe 29.8 2hym_A 
HN
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
148IEb 0.0 2hym_A 
I
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
149NEe 25.5 2hym_A 
NS
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
150VEb 0.0 2hym_A 
V
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
151MEb 16.9 2hym_A 
NTM
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
152VEb 0.0 2hym_A 
VM
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
153KEe 34.9 2hym_A 
KE
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
154F b 5.3 2hym_A 
F
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
155P b 5.4 2hym_A 
P
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
156SSe 90.6 2hym_A 
KSGR
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
157I e 25.7 2hym_A 
I
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
158V e 63.3 2hym_A 
IVLP
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
159EGb 18.6 2hym_A hetero IFNA2_HUMAN 
SQE
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
160EGe 88.4 2hym_A hetero IFNA2_HUMAN 
E
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
161EGe 69.8 2hym_A hetero IFNA2_HUMAN 
EK
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
162L e 36.0 2hym_A hetero IFNA2_HUMAN 
LM
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
163Q e 90.8 2hym_A hetero IFNA2_HUMAN 
QK
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
164F b 17.2 2hym_A 
FT
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
165D e 74.7 2hym_A hetero IFNA2_HUMAN 
YTD
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
166L b 11.8 2hym_A hetero IFNA2_HUMAN 
LP
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
167SEe 21.1 2hym_A hetero IFNA2_HUMAN 
AFS
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
168LEb 0.0 2hym_A 
FVL
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
169VEb 2.7 2hym_A 
IVLAEGKSTDFNPQRCHMWY
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
170IEb 0.0 2hym_A 
IK
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
171EEb 3.5 2hym_A 
E
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
172EEb 0.0 2hym_A 
EQ
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
173QEe 35.2 2hym_A 
HIQ
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
174SEb 0.0 2hym_A 
AGS
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
175ETe 49.2 2hym_A 
GDE
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
176GTe 40.5 2hym_A 
NSG
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
177IEe 65.5 2hym_A 
SVI
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
178VEe 70.7 2hym_A 
VR
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
179KEe 34.9 2hym_A 
K
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
180KEe 51.4 2hym_A 
KR
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
181HEb 19.9 2hym_A 
H
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
182K e 65.6 2hym_A metal CL 
QEK
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
183P e 22.5 2hym_A metal CL 
P
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
184E e 69.3 2hym_A 
QKE
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
185I b 11.1 2hym_A 
IV
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
186KTe 74.1 2hym_A hetero IFNA2_HUMAN 
TNK
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
187GTe 54.8 2hym_A 
GLADEIKPRSTVCFHMNQY
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
188NTe 39.4 2hym_A 
N
 CARBOHYD /note="N-linked (GlcNAc...) asparagine" TOPO_DOM /note="Extracellular" CARBOHYD /note="N-linked (GlcNAc...) asparagine" TOPO_DOM /note="Extracellular"
189MSb 3.9 2hym_A 
IVM
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
190SSe 39.8 2hym_A 
TS
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
191GSb 14.3 2hym_A 
GEK
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
192NEe 75.2 2hym_A 
N
 CARBOHYD /note="N-linked (GlcNAc...) asparagine" TOPO_DOM /note="Extracellular" CARBOHYD /note="N-linked (GlcNAc...) asparagine" TOPO_DOM /note="Extracellular"
193FEb 1.0 2hym_A 
F
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
194TEe 44.8 2hym_A 
TN
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
195YEe 23.0 2hym_A metal CL 
YF
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
196IEe 54.4 2hym_A 
VI
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular" I->V:(75.0 %):LB/B - dbSNP:rs1786022
197IEb 5.3 2hym_A 
IL
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
198DEe 50.6 2hym_A 
DR
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
199K e 83.5 2hym_A metal CL 
KD
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
200L b 3.4 2hym_A 
L
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
201I e 89.5 2hym_A 
IL
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
202PSe 31.8 2hym_A 
P
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
203NSe 37.0 2hym_A 
NK
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
204T b 0.0 2hym_A 
T
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
205NEe 38.2 2hym_A 
N
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
206YEb 0.0 2hym_A 
Y
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
207CEb 5.3 2hym_A 
C
 DISULFID ECO:0000269|PubMed:20496919, ECO:0000269|PubMed:21819146, ECO:0000269|PubMed:21854986, ECO:0007744|PDB:1N6U, ECO:0007744|PDB:1N6V, ECO:0007744|PDB:2HYM, ECO:0007744|PDB:2KZ1, ECO:0007744|PDB:2LAG, ECO:0007744|PDB:3S8W, ECO:0007744|PDB:3S9D, ECO:0007744|PDB:3SE3, ECO:0007744|PDB:3SE4" TOPO_DOM /note="Extracellular" DISULFID ECO:0000269|PubMed:20496919, ECO:0000269|PubMed:21819146, ECO:0000269|PubMed:21854986, ECO:0007744|PDB:1N6U, ECO:0007744|PDB:1N6V, ECO:0007744|PDB:2HYM, ECO:0007744|PDB:2KZ1, ECO:0007744|PDB:2LAG, ECO:0007744|PDB:3S8W, ECO:0007744|PDB:3S9D, ECO:0007744|PDB:3SE3, ECO:0007744|PDB:3SE4" TOPO_DOM /note="Extracellular"
208VEb 0.0 2hym_A 
VI
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
209SEb 0.0 2hym_A 
S
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
210VEb 3.3 2hym_A 
VL
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
211YEb 1.3 2hym_A 
Y
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
212LEb 2.8 2hym_A 
FL
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
213EEb 15.6 2hym_A hetero IFNA2_HUMAN 
ELADGIKPRSTVCFHMNQY
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
214HSe 32.5 2hym_A hetero IFNA2_HUMAN IFNW1_HUMAN 
PHLADEGIKRSTVCFMNQY
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
215SSe 79.7 2hym_A hetero IFNA2_HUMAN 
KSLADEGIPRTVCFHMNQY
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular" S->G:(2.0 %):LB/B - dbSNP:rs7476057
216DSe 44.4 2hym_A hetero IFNA2_HUMAN 
D
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
217ESe 50.8 2hym_A hetero IFNW1_HUMAN 
PDE
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
218QTe 78.6 2hym_A hetero IFNA2_HUMAN IFNW1_HUMAN 
RDQ
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
219ATb 5.4 2hym_A 
KPA
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
220V e 60.0 2hym_A 
IAV
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
221I b 16.4 2hym_A 
IN
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
222K e 41.0 2hym_A 
KR
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
223S b 3.9 2hym_A 
S
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
224P e 69.8 2hym_A 
P
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
225L e 55.1 2hym_A 
L
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
226KEe 32.1 2hym_A 
K
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
227CEe 54.0 2hym_A 
C
 DISULFID ECO:0000269|PubMed:20496919, ECO:0000269|PubMed:21819146, ECO:0000269|PubMed:21854986, ECO:0007744|PDB:1N6U, ECO:0007744|PDB:1N6V, ECO:0007744|PDB:2HYM, ECO:0007744|PDB:2KZ1, ECO:0007744|PDB:2LAG, ECO:0007744|PDB:3S8W, ECO:0007744|PDB:3S9D, ECO:0007744|PDB:3SE3, ECO:0007744|PDB:3SE4" TOPO_DOM /note="Extracellular" DISULFID ECO:0000269|PubMed:20496919, ECO:0000269|PubMed:21819146, ECO:0000269|PubMed:21854986, ECO:0007744|PDB:1N6U, ECO:0007744|PDB:1N6V, ECO:0007744|PDB:2HYM, ECO:0007744|PDB:2KZ1, ECO:0007744|PDB:2LAG, ECO:0007744|PDB:3S8W, ECO:0007744|PDB:3S9D, ECO:0007744|PDB:3SE3, ECO:0007744|PDB:3SE4" TOPO_DOM /note="Extracellular"
228TEe 29.2 2hym_A 
IT
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
229LEe 65.7 2hym_A 
LV
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
230L b 0.0 2hym_A 
LF
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
231P e 38.8 2hym_A 
RQP
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
232P e 39.5 2hym_A 
P
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
233G e 58.3 2hym_A 
GR
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
234Q e 73.0 2hym_A 
QR
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
235ESe 68.3 2hym_A 
E
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
236S e 73.4 2hym_A 
S
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
237E e 92.5 2hym_A 
EG
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
238S---- 
SL
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
239A---- 
SA
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
240E---- 
E
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
241S---- 
SP
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
242A---- 
A
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
243K---- 
TKLADEGIPRSVCFHMNQY
 TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
244I---- 
I
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
245G---- 
GV
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
246G---- 
G
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
247I---- 
I
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
248I---- 
ITL
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
249T---- 
TI
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
250V---- 
LSV
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
251F---- 
FC
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
252L---- 
L
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
253I---- 
IVL
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
254A---- 
AVT
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
255L---- 
AML
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
256V---- 
V
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
257L---- 
FLC
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
258T---- 
IVT
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
259S---- 
S
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
260T---- 
T
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
261I---- 
IV
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
262V---- 
VM
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
263T---- 
IMT
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
264L---- 
L
 TRANSMEM /note="Helical" TRANSMEM /note="Helical"
265K---- 
K
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
266W---- 
RW
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
267I---- 
I
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
268G---- 
G
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
269Y---- 
Y
 MUTAGEN /note="Y->F: Does not inhibit STAT1, STAT2 and STAT3 activation by IFN. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-306; F-316; F- 318; F-337; F-411 and F-512. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-306; F-316; F-318; F-411 and F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-306; F-316; F-318 and F-337." ECO:0000269|PubMed:12105218" TOPO_DOM /note="Cytoplasmic" MUTAGEN /note="Y->F: Does not inhibit STAT1, STAT2 and STAT3 activation by IFN. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-306; F-316; F- 318; F-337; F-411 and F-512. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-306; F-316; F-318; F-411 and F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-306; F-316; F-318 and F-337." ECO:0000269|PubMed:12105218" TOPO_DOM /note="Cytoplasmic"
270I---- 
I
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
271C---- 
C
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
272L---- 
L
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
273R---- 
RK
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
274N---- 
ND
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
275S---- 
DNS
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
276L---- 
LF
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
277P---- 
P
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
278K---- 
KNE
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
279V---- 
VA
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
280L---- 
L
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
281N---- 
N
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
282F---- 
F
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
283H---- 
YRH
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" H->R:(31.0 %):LB/B - dbSNP:rs7635080
284N---- 
KHN
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
285F---- 
FL
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
286L---- 
LS
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
287A---- 
VTA
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
288W---- 
W
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
289P---- 
VIP
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
290F---- 
FI
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
291P---- 
PA
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
292N---- 
EN
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
293L---- 
LR
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
294P---- 
PS
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
295P---- 
P
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" P->L:(0.0 %):LB/B - dbSNP:rs7597449
296L---- 
LS
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
297E---- 
E
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
298A---- 
AK
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
299M---- 
MIV
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
300D---- 
DA
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
301M---- 
TRM
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
302V---- 
VL
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
303E---- 
E
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
304V---- 
VI
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
305I---- 
I
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
306Y---- 
HPY
 MUTAGEN /note="Y->F: Does not inhibit STAT1, STAT2 and STAT3 activation by IFN. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-316; F- 318; F-337; F-411 and F-512. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-316; F-318; F-411 and F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-316; F-318 and F-337." ECO:0000269|PubMed:12105218" TOPO_DOM /note="Cytoplasmic" MUTAGEN /note="Y->F: Does not inhibit STAT1, STAT2 and STAT3 activation by IFN. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-316; F- 318; F-337; F-411 and F-512. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-316; F-318; F-411 and F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-316; F-318 and F-337." ECO:0000269|PubMed:12105218" TOPO_DOM /note="Cytoplasmic"
307I---- 
ITV
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
308N---- 
NT
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
309R---- 
RK
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
310K---- 
K
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
311K---- 
K
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
312K---- 
KR
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
313V---- 
VLE
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
314W---- 
W
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
315D---- 
ND
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
316Y---- 
Y
 MUTAGEN /note="Y->F: Does not inhibit STAT1, STAT2 and STAT3 activation by IFN. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F- 318; F-337; F-411 and F-512. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F-318; F-411 and F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F-318 and F-337." ECO:0000269|PubMed:12105218" TOPO_DOM /note="Cytoplasmic" MUTAGEN /note="Y->F: Does not inhibit STAT1, STAT2 and STAT3 activation by IFN. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F- 318; F-337; F-411 and F-512. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F-318; F-411 and F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F-318 and F-337." ECO:0000269|PubMed:12105218" TOPO_DOM /note="Cytoplasmic"
317N---- 
ND
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
318Y---- 
Y
 MUTAGEN /note="Y->F: Does not inhibit STAT1, STAT2 and STAT3 activation by IFN. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F- 316; F-337; F-411 and F-512. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F-316; F-411 and F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F-316 and F-337." ECO:0000269|PubMed:12105218" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" MUTAGEN /note="Y->F: Does not inhibit STAT1, STAT2 and STAT3 activation by IFN. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F- 316; F-337; F-411 and F-512. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F-316; F-411 and F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F-316 and F-337." ECO:0000269|PubMed:12105218" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" Y->C:(0.0 %):LB/B - dbSNP:rs7565715
319D---- 
DE
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
320D---- 
D
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
321E---- 
EG
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
322S---- 
SN
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
323D---- 
D
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
324S---- 
SI
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" S->N:(0.0 %):LB/B - dbSNP:rs2014112
325D---- 
DE
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
326T---- 
NTLADEGIKPRSVCFHMQY
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
327E---- 
E
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
328A---- 
AEV
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
329A---- 
AV
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
330P---- 
P
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
331R---- 
RTH
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
332T---- 
ATLV
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
333S---- 
SIN
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
334G---- 
SVG
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
335G---- 
GT
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
336G---- 
G
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
337Y---- 
Y
 MOD_RES /note="Phosphotyrosine" ECO:0000269|PubMed:12105218" MUTAGEN /note="Y->F: Does not inhibit STAT1, STAT2 and STAT3 activation by IFN. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F- 316; F-318; F-411 and F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F-316 and F-318." ECO:0000269|PubMed:12105218" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" MOD_RES /note="Phosphotyrosine" ECO:0000269|PubMed:12105218" MUTAGEN /note="Y->F: Does not inhibit STAT1, STAT2 and STAT3 activation by IFN. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F- 316; F-318; F-411 and F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F-316 and F-318." ECO:0000269|PubMed:12105218" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
338T---- 
T
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
339M---- 
MK
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
340H---- 
H
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
341G---- 
G
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
342L---- 
L
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
343T---- 
T
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
344V---- 
GVALSDEFIKNPQRTY
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
345R---- 
RKAGLSDEFINPQTVY
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
346P---- 
PAGLSDEFIKNQRTVY
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" P->S:(2.0 %):LB/B - dbSNP:rs1485198
347L---- 
LTAGSDEFIKNPQRVY
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
348G---- 
GQS
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
349Q---- 
QKT
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
350A---- 
TAL
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
351S---- 
SAC
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
352A---- 
ADP
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
353T---- 
TS
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
354S---- 
SL
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
355T---- 
TAE
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
356E---- 
SEDT
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
357S---- 
SPC
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
358Q---- 
EQPS
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
359L---- 
LSADEGIKPRTVCFHMNQY
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
360I---- 
ILEADGKPRSTVCFHMNQY
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
361D---- 
DE
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
362P---- 
PCE
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" P->S:(0.0 %):LB/B - dbSNP:rs1441207
363E---- 
LEPS
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
364S---- 
SH
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
365E---- 
EA
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
366E---- 
E
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
367E---- 
ED
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
368P---- 
PS
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
369D---- 
YGD
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
370L---- 
LA
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
371P---- 
PE
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
372E---- 
E
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
373V---- 
SVGR
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
374D---- 
D
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
375V---- 
AEV
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
376E---- 
E
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
377L---- 
LT
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
378P---- 
P
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
379T---- 
TAM
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
380M---- 
AEM
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
381P---- 
PA
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
382K---- 
GK
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
383D---- 
PAD
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
384S---- 
GS
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
385P---- 
PL
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" P->L:(22.0 %):LB/B - dbSNP:rs1231284
386Q---- 
WSQ
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
387Q---- 
QLADEGIKPRSTVCFHMNY
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
388L---- 
SLADEGIKPRTVCFHMNQY
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
389E---- 
E
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
390L---- 
GDL
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
391L---- 
TPL
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
392S---- 
STG
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
393G---- 
G
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
394P---- 
PG
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
395C---- 
YC
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
396E---- 
EQ
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
397R---- 
RT
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
398R---- 
R
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
399K---- 
KG
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
400S---- 
ST
 MOD_RES /note="Phosphoserine" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" MOD_RES /note="Phosphoserine" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
401P---- 
LVP
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
402L---- 
LW
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
403Q---- 
QE
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
404D---- 
D
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
405P---- 
PS
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
406F---- 
FT
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
407P---- 
PS
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
408E---- 
ER
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
409E---- 
E
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
410D---- 
D
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
411Y---- 
SNY
 MUTAGEN /note="Y->F: Does not inhibit STAT1, STAT2 and STAT3 activation by IFN. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F- 316; F-318; F-337 and F-512. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F-316; F-318 and F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-512." ECO:0000269|PubMed:12105218" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" MUTAGEN /note="Y->F: Does not inhibit STAT1, STAT2 and STAT3 activation by IFN. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F- 316; F-318; F-337 and F-512. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F-316; F-318 and F-512. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-512." ECO:0000269|PubMed:12105218" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
412S---- 
SD
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
413S---- 
S
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
414T---- 
TM
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
415E---- 
ED
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
416G---- 
GE
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
417S---- 
SP
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
418G---- 
GE
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
419G---- 
GD
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
420R---- 
RN
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
421I---- 
I
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
422T---- 
VIT
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
423F---- 
F
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
424N---- 
N
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
425V---- 
V
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
426D---- 
ND
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
427L---- 
L
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
428N---- 
N
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
429S---- 
S
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
430V---- 
V
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
431F---- 
FC
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
432L---- 
LV
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
433R---- 
R
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
434V---- 
VA
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
435L---- 
L
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
436D---- 
HDLAEGKSTVFINPQRCMWY
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
437D---- 
DLAEGKSTVFINPQRCHMWY
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
438E---- 
E
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
439D---- 
D
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
440S---- 
DAS
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
441D---- 
KSD
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
442D---- 
DE
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
443L---- 
SLADEGIKPRTVCFHMNQY
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
444E---- 
ELADGIKPRSTVCFHMNQY
 REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic" REGION /note="Mediates interaction with STAT2 (and required for the recruitment of USP18)" TOPO_DOM /note="Cytoplasmic"
445A---- 
VALDEGIKPRSTCFHMNQY
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
446P---- 
TPLADEGIKRSVCFHMNQY
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
447L---- 
LADEGIKPRSTVCFHMNQY
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
448M---- 
MT
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
449L---- 
LS
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
450S---- 
SP
 TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" S->L:(0.0 %):LB/B - dbSNP:rs8667333
451S---- 
SL
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
452H---- 
EHCP
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
453L---- 
PEL
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
454E---- 
ED
 TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
455E---- 
ET
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
456M---- 
IMAT
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
457V---- 
VL
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
458D---- 
LDE
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
459P---- 
DPEL
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
460E---- 
E
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
461D---- 
DG
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
462P---- 
PL
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
463D---- 
QDNS
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
464N---- 
ERN
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
465V---- 
TV
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
466Q---- 
EQ
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
467S---- 
S
 MOD_RES /note="Phosphoserine" COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" MOD_RES /note="Phosphoserine" COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
468N---- 
SDN
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
469H---- 
LHV
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
470L---- 
LR
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
471L---- 
VIL
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
472A---- 
A
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
473S---- 
SG
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
474G---- 
GE
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
475E---- 
ED
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
476G---- 
GR
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
477T---- 
T
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
478Q---- 
Q
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
479P---- 
PL
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
480T---- 
PT
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
481F---- 
FL
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
482P---- 
PT
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
483S---- 
SDN
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
484P---- 
PL
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
485S---- 
SP
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
486S---- 
SMT
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
487E---- 
EQ
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
488G---- 
CDG
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
489L---- 
LP
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
490W---- 
WR
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
491S---- 
PTS
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
492E---- 
EQ
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
493D---- 
D
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
494A---- 
AG
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
495P---- 
PSL
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
496S---- 
S
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
497D---- 
DE
 COMPBIAS /note="Polar residues" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" COMPBIAS /note="Polar residues" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
498Q---- 
KQ
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
499S---- 
S
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
500D---- 
D
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
501T---- 
T
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
502S---- 
S
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
503E---- 
DE
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
504S---- 
SP
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
505D---- 
D
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
506V---- 
VA
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
507D---- 
D
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
508L---- 
VLIM
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
509G---- 
G
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
510D---- 
D
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
511G---- 
G
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
512Y---- 
Y
 MOD_RES /note="Phosphotyrosine" ECO:0000269|PubMed:12105218" MUTAGEN /note="Y->F: Does not inhibit STAT1, STAT2 and STAT3 activation by IFN. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F- 316; F-318; F-337 and F-411. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F-316; F-318 and F-411. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-411." ECO:0000269|PubMed:12105218" REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" MOD_RES /note="Phosphotyrosine" ECO:0000269|PubMed:12105218" MUTAGEN /note="Y->F: Does not inhibit STAT1, STAT2 and STAT3 activation by IFN. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F- 316; F-318; F-337 and F-411. Inhibits STAT1, STAT2 and STAT3 activation by IFN; when associated with F-269; F-306; F-316; F-318 and F-411. Does not inhibit STAT1, STAT2 and STAT3 activation by IFN; when associated with F-411." ECO:0000269|PubMed:12105218" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
513I---- 
I
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
514M---- 
MV
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"
515R---- 
R
 REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED REGION /note="Disordered" TOPO_DOM /note="Cytoplasmic"