Contact Molecules for Homologous Proteins

[Full Bars]
[SiteTable]


Summary Bars[0.0 %]


[Back to Search Page]
[Back to HOMCOS]

[SupCon3D]
[help] 		seq_id(%): [0] [30] [40] [50] [60] [70] [80] [90] [95] [100]
[show] [download] [help]
PID QueryLength Homolgous Sequence in PDB UniProt Query TITLE
3177153 212 24 P05231(IL6_HUMAN) RecName: Full=Interleukin-6 ; Short=IL-6;AltName: Full=B-cell stimulatory factor 2; Short=BSF-2;AltName: Full=CTL differentiation factor; Short=CDF;AltName: Full=Hybridoma growth factor;AltName: Full=Interferon beta-2; Short=IFN-beta-2;Flags: Precursor;
QUERYSEQ 
MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVL
IQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]

UniProt Feature Tables [P05231(IL6_HUMAN)]

212
region name description
1-29 SIGNAL ECO:0000269|PubMed:2610854, ECO:0000269|PubMed:3279116"
30-212 CHAIN /note="Interleukin-6" /id="PRO_0000015582"
1-43 DISORDER predicted by DISOPRED

MONOMER
212
pdb_id a1 identity[%]2 description
4cni C 100.0 IL6_HUMAN INTERLEUKIN-6
2l3y A 40.7 IL6_MOUSE Interleukin-6 
1.a1:asym_id for the homologue. 2.identity[%]2:sequence identity between the query and the homologue.
HETERO
212 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1i1r[2] A IL6RB_HUMAN INTERLEUKIN-6 RECEPTOR BETA CHAIN[301 aa] B 0.0
/26.5		 10
/11		 Q98823_HHV8 VIRAL IL-6
1i1r[2] A IL6RB_HUMAN INTERLEUKIN-6 RECEPTOR BETA CHAIN[301 aa] B 26.3
/26.5		 19
/19		 Q98823_HHV8 VIRAL IL-6
1p9m[2] A IL6RB_HUMAN Interleukin-6 receptor beta chain[298 aa] B 100.0
/100.0		 12
/12		 IL6_HUMAN Interleukin-6
1p9m[2] A IL6RB_HUMAN Interleukin-6 receptor beta chain[298 aa] B 100.0
/100.0		 14
/14		 IL6_HUMAN Interleukin-6
1p9m[2] C IL6RA_HUMAN Interleukin-6 receptor alpha chain[201 aa] B 100.0
/100.0		 13
/13		 IL6_HUMAN Interleukin-6
5fuc[2] D D6R9R8_HUMAN IL6RA_HUMAN INTERLEUKIN-6 RECEPTOR SUBUNIT ALPHA, INTERLEUKIN-.. A 100.0
/99.3		 14
/14		 IL6_HUMAN INTERLEUKIN-6
8qy5[4] C IL6RA_HUMAN Interleukin-6 receptor subunit alpha[201 aa] B 100.0
/100.0		 13
/13		 IL6_HUMAN Interleukin-6
4cni[2] E OLOKIZUMAB HEAVY CHAIN, FAB PORTION[219 aa] C 100.0
/100.0		 13
/13		 IL6_HUMAN INTERLEUKIN-6
4cni[2] F OLOKIZUMAB LIGHT CHAIN, FAB PORTION[214 aa] C 100.0
/100.0		 6
/6		 IL6_HUMAN INTERLEUKIN-6
4j4l[2] A A4L9V2_LISMN Q4G1L3_EPTBU Internalin B,REPEAT MODULES,Variable lymphocyte re.. C 100.0
/99.4		 18
/19		 IL6_HUMAN Interleukin-6
4o9h[1] B Heavy Chain of the Camelid Fab fragment 61H7[200 a.. A 100.0
/100.0		 10
/10		 IL6_HUMAN Interleukin-6
4o9h[1] C Light Chain of the Camelid Fab fragment 61H7[211 a.. A 100.0
/100.0		 7
/7		 IL6_HUMAN Interleukin-6
4zs7[1] B Llama Fab fragment 68F2 heavy chain[222 aa] A 100.0
/100.0		 13
/13		 IL6_HUMAN Interleukin-6
4zs7[1] C Llama Fab fragment 68F2 light chain[210 aa] A 100.0
/100.0		 11
/11		 IL6_HUMAN Interleukin-6
5fuc[1] E VHH6[110 aa] B 100.0
/100.0		 7
/7		 IL6_HUMAN INTERLEUKIN-6
8d82[2] A IL6RA_HUMAN Soluble interleukin-6 receptor subunit alpha[296 a.. B 100.0
/100.0		 14
/14		 IL6_HUMAN Interleukin-6
8d82[2] C IL6RB_HUMAN Interleukin-6 receptor subunit beta[589 aa] B 100.0
/100.0		 13
/13		 IL6_HUMAN Interleukin-6
8d82[2] F IL6RB_HUMAN Interleukin-6 receptor subunit beta[589 aa] B 100.0
/100.0		 13
/13		 IL6_HUMAN Interleukin-6
8qy5[4] A IL6RB_MOUSE Interleukin-6 receptor subunit beta[584 aa] B 100.0
/100.0		 11
/11		 IL6_HUMAN Interleukin-6
8qy5[4] F IL6RB_MOUSE Interleukin-6 receptor subunit beta[584 aa] B 100.0
/100.0		 15
/15		 IL6_HUMAN Interleukin-6
5fuc[1] F VHH6[124 aa] A 90.0
/99.3		 10
/11		 IL6_HUMAN INTERLEUKIN-6
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
NUCLEOTIDE
212 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
4ni7[1] B SOMAmer SL1025 A 100.0
/100.0		 19
/19		 IL6_HUMAN Interleukin-6
4ni9[2] A SOMAmer SL1025 B 100.0
/100.0		 22
/22		 IL6_HUMAN Interleukin-6
4ni9[2] D SOMAmer SL1025 B 100.0
/100.0		 5
/5		 IL6_HUMAN Interleukin-6
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
HOMO
212 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1alu[2] A IL6_HUMAN INTERLEUKIN-6[157 aa] A 100.0
/100.0		 22
/22		 IL6_HUMAN INTERLEUKIN-6
1alu[2] A IL6_HUMAN INTERLEUKIN-6[157 aa] A 100.0
/100.0		 11
/11		 IL6_HUMAN INTERLEUKIN-6
4ni9[2] C IL6_HUMAN Interleukin-6[148 aa] B 100.0
/100.0		 3
/3		 IL6_HUMAN Interleukin-6
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.
PRECIPITANT
212 pdb_id contact mol homologue
a3 description a4 identity[%]5 Ncon6 description
1alu[8] B SO4
SULFATE ION[5 atoms] 		A 100.0
/100.0		 3
/3		 IL6_HUMAN INTERLEUKIN-6
1alu[2] B SO4
SULFATE ION[5 atoms] 		A 100.0
/100.0		 2
/2		 IL6_HUMAN INTERLEUKIN-6
1alu[5] D SO4
SULFATE ION[5 atoms] 		A 100.0
/100.0		 2
/2		 IL6_HUMAN INTERLEUKIN-6
1alu[3] E SO4
SULFATE ION[5 atoms] 		A 100.0
/100.0		 5
/5		 IL6_HUMAN INTERLEUKIN-6
4cni[2] I SO4
SULFATE ION[5 atoms] 		C 100.0
/100.0		 3
/3		 IL6_HUMAN INTERLEUKIN-6
1alu[5] F TLA
L(+)-TARTARIC ACID[10 atoms] 		A 100.0
/100.0		 4
/4		 IL6_HUMAN INTERLEUKIN-6
3.a3:asym_id for the contact molecule. 4.a4:asym_id for the template homologue. 5.identity[%]5:sequence identity between the query and the template homologue only for the contact residues. Number after the slash / is sequence identity for all the aligned region. 6.Ncon6:number of aligned contact residues for the query. Number after the slash / is number of contact residues in the template homologue.