PSIBLAST 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Stephen F.
Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005)
"Protein database searches using compositionally adjusted
substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: uniprot_sprot.fasta
571,282 sequences; 206,678,396 total letters
Results from round 1
Query= sp|P05231|IL6_HUMAN Interleukin-6 OS=Homo sapiens OX=9606 GN=IL6
PE=1 SV=1
Length=212
Score E
Sequences producing significant alignments: (Bits) Value
sp|P05231|IL6_HUMAN Interleukin-6 OS=Homo sapiens OX=9606 GN=IL6 ... 437 1e-157
sp|P79341|IL6_MACFA Interleukin-6 OS=Macaca fascicularis OX=9541 ... 422 8e-152
sp|P51494|IL6_MACMU Interleukin-6 OS=Macaca mulatta OX=9544 GN=IL... 421 2e-151
sp|Q5I6E3|IL6_MACTH Interleukin-6 OS=Macaca thibetana OX=54602 GN... 420 5e-151
sp|P46650|IL6_CERAT Interleukin-6 OS=Cercocebus atys OX=9531 GN=I... 420 6e-151
sp|Q8MKH0|IL6_SAISC Interleukin-6 OS=Saimiri sciureus OX=9521 GN=... 377 9e-134
sp|Q865W7|IL6_CAMBA Interleukin-6 OS=Camelus bactrianus OX=9837 G... 267 1e-90
sp|Q95181|IL6_HORSE Interleukin-6 OS=Equus caballus OX=9796 GN=IL... 267 2e-90
sp|P26893|IL6_PIG Interleukin-6 OS=Sus scrofa OX=9823 GN=IL6 PE=2... 266 3e-90
sp|Q865X6|IL6_LAMGL Interleukin-6 OS=Lama glama OX=9844 GN=IL6 PE... 266 5e-90
sp|P41683|IL6_FELCA Interleukin-6 OS=Felis catus OX=9685 GN=IL6 P... 255 1e-85
sp|P41323|IL6_CANLF Interleukin-6 OS=Canis lupus familiaris OX=96... 254 1e-85
sp|Q9XT80|IL6_DELLE Interleukin-6 OS=Delphinapterus leucas OX=974... 252 1e-84
sp|Q28747|IL6_ORCOR Interleukin-6 (Fragment) OS=Orcinus orca OX=9... 251 4e-84
sp|A3FBE9|IL6_MUSPF Interleukin-6 OS=Mustela putorius furo OX=966... 249 1e-83
sp|Q28819|IL6_PHOVI Interleukin-6 (Fragment) OS=Phoca vitulina OX... 246 4e-82
sp|Q25BC2|IL6_VULVU Interleukin-6 OS=Vulpes vulpes OX=9627 GN=IL6... 237 1e-78
sp|Q28319|IL6_CAPHI Interleukin-6 OS=Capra hircus OX=9925 GN=IL6 ... 227 1e-74
sp|P26892|IL6_BOVIN Interleukin-6 OS=Bos taurus OX=9913 GN=IL6 PE... 225 4e-74
sp|P29455|IL6_SHEEP Interleukin-6 OS=Ovis aries OX=9940 GN=IL6 PE... 225 7e-74
sp|Q2MH06|IL6_BUBCA Interleukin-6 OS=Bubalus carabanensis OX=3460... 224 2e-73
sp|Q6V919|IL6_BUBBU Interleukin-6 OS=Bubalus bubalis OX=89462 GN=... 224 2e-73
sp|O35736|IL6_MARMO Interleukin-6 OS=Marmota monax OX=9995 GN=IL6... 191 2e-60
sp|Q9MZR1|IL6_RABIT Interleukin-6 OS=Oryctolagus cuniculus OX=998... 178 3e-55
sp|P20607|IL6_RAT Interleukin-6 OS=Rattus norvegicus OX=10116 GN=... 175 2e-54
sp|P08505|IL6_MOUSE Interleukin-6 OS=Mus musculus OX=10090 GN=Il6... 172 4e-53
sp|P41693|IL6_NEOVI Interleukin-6 (Fragment) OS=Neovison vison OX... 139 5e-41
sp|Q90YI0|IL6_CHICK Interleukin-6 OS=Gallus gallus OX=9031 GN=IL6... 135 2e-38
sp|Q2HRC7|VIL6_HHV8P Viral interleukin-6 homolog OS=Human herpesv... 78.2 1e-16
sp|A0S0B0|IL6_PAROL Interleukin-6 OS=Paralichthys olivaceus OX=82... 50.8 1e-06
sp|P13854|MGF_CHICK Myelomonocytic growth factor OS=Gallus gallus... 48.5 7e-06
sp|Q0GGL7|IL6_ONCMY Interleukin-6 OS=Oncorhynchus mykiss OX=8022 ... 47.8 1e-05
sp|Q6L6X6|IL6_TAKRU Interleukin-6 OS=Takifugu rubripes OX=31033 G... 47.4 2e-05
sp|P09920|CSF3_MOUSE Granulocyte colony-stimulating factor OS=Mus... 40.8 0.003
sp|O18739|CCN2_BOVIN CCN family member 2 OS=Bos taurus OX=9913 GN... 34.7 0.44
sp|Q0A783|NUOI_ALKEH NADH-quinone oxidoreductase subunit I OS=Alk... 34.3 0.46
sp|Q8TXI4|RAD50_METKA DNA double-strand break repair Rad50 ATPase... 33.5 1.3
sp|Q2NV92|EX7S_SODGM Exodeoxyribonuclease 7 small subunit OS=Soda... 30.0 4.8
sp|C6DB39|EX7S_PECCP Exodeoxyribonuclease 7 small subunit OS=Pect... 29.6 6.3
sp|O02708|CSF3_FELCA Granulocyte colony-stimulating factor (Fragm... 30.8 6.6
sp|Q6D842|EX7S_PECAS Exodeoxyribonuclease 7 small subunit OS=Pect... 29.6 6.7
sp|P44647|PRIA_HAEIN Primosomal protein N' OS=Haemophilus influen... 31.6 6.9
sp|P06668|VIRD2_RHIRD T-DNA border endonuclease VirD2 OS=Rhizobiu... 30.8 9.5
>sp|P05231|IL6_HUMAN Interleukin-6 OS=Homo sapiens OX=9606 GN=IL6
PE=1 SV=1
Length=212
Score = 437 bits (1123), Expect = 1e-157, Method: Compositional matrix adjust.
Identities = 212/212 (100%), Positives = 212/212 (100%), Gaps = 0/212 (0%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI
Sbjct 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL
Sbjct 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ
Sbjct 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
Sbjct 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
>sp|P79341|IL6_MACFA Interleukin-6 OS=Macaca fascicularis OX=9541
GN=IL6 PE=2 SV=1
Length=212
Score = 422 bits (1085), Expect = 8e-152, Method: Compositional matrix adjust.
Identities = 205/212 (97%), Positives = 208/212 (98%), Gaps = 0/212 (0%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS STSAFGPVAFSLGLLLVLPAAFPAPV PGEDSKDVAAPH QPLTSSERIDK IRYI
Sbjct 1 MNSVSTSAFGPVAFSLGLLLVLPAAFPAPVLPGEDSKDVAAPHSQPLTSSERIDKHIRYI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
LDGISALRKETCN+SNMCESSKEALAENNLNLPKMAEKDGCFQSGFNE+TCLVKIITGLL
Sbjct 61 LDGISALRKETCNRSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEDTCLVKIITGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTP+PTTNASLLTKLQ
Sbjct 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPEPTTNASLLTKLQ 180
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
Sbjct 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
>sp|P51494|IL6_MACMU Interleukin-6 OS=Macaca mulatta OX=9544 GN=IL6
PE=2 SV=1
Length=212
Score = 421 bits (1083), Expect = 2e-151, Method: Compositional matrix adjust.
Identities = 204/212 (96%), Positives = 209/212 (99%), Gaps = 0/212 (0%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNSFSTSAFGPVAFSLGLLLVLPAAFPAPV PGEDSK+VAAPH QPLTSSERIDK IRYI
Sbjct 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVLPGEDSKNVAAPHSQPLTSSERIDKHIRYI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
LDGISALRKETCN+SNMCESSKEALAENNLNLPKMAEKDGCFQSGFNE+TCLVKIITGLL
Sbjct 61 LDGISALRKETCNRSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEDTCLVKIITGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTP+PTTNASLLTKLQ
Sbjct 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPEPTTNASLLTKLQ 180
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
AQNQWLQDMTTHLILRSFKEFLQS+LRALRQM
Sbjct 181 AQNQWLQDMTTHLILRSFKEFLQSNLRALRQM 212
>sp|Q5I6E3|IL6_MACTH Interleukin-6 OS=Macaca thibetana OX=54602
GN=IL6 PE=2 SV=1
Length=212
Score = 420 bits (1080), Expect = 5e-151, Method: Compositional matrix adjust.
Identities = 204/212 (96%), Positives = 207/212 (98%), Gaps = 0/212 (0%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS STSAFGPVAFSLGLLLVLPAAFPAPV PGEDSKDVAAPH QPLTSSERIDK IRYI
Sbjct 1 MNSVSTSAFGPVAFSLGLLLVLPAAFPAPVLPGEDSKDVAAPHSQPLTSSERIDKHIRYI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
LDGISALRKETCN+SNMCESSKEALAENNLNLPKMAEKDGCFQSGFNE+TCLVKIITGLL
Sbjct 61 LDGISALRKETCNRSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEDTCLVKIITGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EFEVYLEYLQNRFESSEEQARAVQMSTK LIQFLQKKAKNLDAITTP+PTTNASLLTKLQ
Sbjct 121 EFEVYLEYLQNRFESSEEQARAVQMSTKALIQFLQKKAKNLDAITTPEPTTNASLLTKLQ 180
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
Sbjct 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
>sp|P46650|IL6_CERAT Interleukin-6 OS=Cercocebus atys OX=9531
GN=IL6 PE=2 SV=1
Length=212
Score = 420 bits (1079), Expect = 6e-151, Method: Compositional matrix adjust.
Identities = 203/212 (96%), Positives = 208/212 (98%), Gaps = 0/212 (0%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNSFSTSAFGPVAFSLGLLLVLPAAFPAPV PGEDSKDVAAPH QPLTSSERIDK IRYI
Sbjct 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVLPGEDSKDVAAPHSQPLTSSERIDKHIRYI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
LDGISALRKETCN+SNMC+S+KEALAENNLNLPKMAEKDGCFQSGFNE+TCLVKIITGLL
Sbjct 61 LDGISALRKETCNRSNMCDSTKEALAENNLNLPKMAEKDGCFQSGFNEDTCLVKIITGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQ LQKKAKNLDAITTP+PTTNASLLTKLQ
Sbjct 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQLLQKKAKNLDAITTPEPTTNASLLTKLQ 180
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
Sbjct 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
>sp|Q8MKH0|IL6_SAISC Interleukin-6 OS=Saimiri sciureus OX=9521
GN=IL6 PE=2 SV=1
Length=212
Score = 377 bits (967), Expect = 9e-134, Method: Compositional matrix adjust.
Identities = 186/212 (88%), Positives = 195/212 (92%), Gaps = 0/212 (0%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
M SFSTSAF PVAFSLGLLLV+PAAFPAPV GEDSK+VAAP+RQ LTS+ERIDK I YI
Sbjct 1 MTSFSTSAFRPVAFSLGLLLVMPAAFPAPVTLGEDSKEVAAPNRQLLTSTERIDKHIWYI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
LDGISALRKE CNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCL+KI TGLL
Sbjct 61 LDGISALRKEICNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLLKITTGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EFEVYLEYLQNRFESS+EQA AVQMSTK LIQ LQ+KAKNL AI TPDP TNASLLTKLQ
Sbjct 121 EFEVYLEYLQNRFESSKEQAGAVQMSTKGLIQSLQRKAKNLSAIATPDPATNASLLTKLQ 180
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
AQ+QWLQ +TTHLILRSFKEFLQ SLRALRQM
Sbjct 181 AQDQWLQGVTTHLILRSFKEFLQCSLRALRQM 212
>sp|Q865W7|IL6_CAMBA Interleukin-6 OS=Camelus bactrianus OX=9837
GN=IL6 PE=2 SV=1
Length=211
Score = 267 bits (683), Expect = 1e-90, Method: Compositional matrix adjust.
Identities = 129/212 (61%), Positives = 163/212 (77%), Gaps = 1/212 (0%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS STSAF PVAFSLGLLLV+ AFP PVP GED KD +R P TS ++ ++ I+YI
Sbjct 1 MNSLSTSAFSPVAFSLGLLLVMATAFPTPVPLGEDFKDGTTSNR-PFTSPDKSEELIKYI 59
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L ISA+RKE C K + CE+SKEAL+ENNLNLPKM EKDGCFQSGFN+ETCL++I GLL
Sbjct 60 LGRISAMRKEMCEKYDKCENSKEALSENNLNLPKMTEKDGCFQSGFNQETCLMRITIGLL 119
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EF++YL+YLQN +E + AVQ+STK LIQ L++K K + ++TP+P T +SLL KLQ
Sbjct 120 EFQIYLDYLQNYYEGDKGNTEAVQISTKALIQLLRQKVKQPEEVSTPNPITGSSLLNKLQ 179
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+NQW+++ LILRS ++FLQ SLRA+R M
Sbjct 180 TENQWMKNTKMILILRSLEDFLQFSLRAVRIM 211
>sp|Q95181|IL6_HORSE Interleukin-6 OS=Equus caballus OX=9796 GN=IL6
PE=2 SV=2
Length=208
Score = 267 bits (682), Expect = 2e-90, Method: Compositional matrix adjust.
Identities = 130/212 (61%), Positives = 162/212 (76%), Gaps = 4/212 (2%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS STS PVAFSLGLLLV+ AFP P+P GED P LT++++ + I+YI
Sbjct 1 MNSLSTSTVTPVAFSLGLLLVMATAFPTPLPLGEDETTSNGPL---LTTADKTKQHIKYI 57
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L ISAL+ E CN + CE+SKE LAENNLNLPKMAEKDGCFQSGFN+ETCL+KI TGL
Sbjct 58 LGKISALKNEMCNNFSKCENSKEVLAENNLNLPKMAEKDGCFQSGFNQETCLMKITTGLS 117
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EF++YLEYLQN F+ +E + +Q+STKVL+Q L +K KN + +TTPDPT +SLL KL
Sbjct 118 EFQIYLEYLQNEFKGEKENIKTMQISTKVLVQILMQKMKNPE-VTTPDPTAKSSLLAKLH 176
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+QN+WL++ TTHLILRS ++FLQ SLRA+R M
Sbjct 177 SQNEWLKNTTTHLILRSLEDFLQFSLRAVRIM 208
>sp|P26893|IL6_PIG Interleukin-6 OS=Sus scrofa OX=9823 GN=IL6
PE=2 SV=2
Length=212
Score = 266 bits (681), Expect = 3e-90, Method: Compositional matrix adjust.
Identities = 130/212 (61%), Positives = 162/212 (76%), Gaps = 0/212 (0%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS STSAF PVAFSLGLLLV+ AFP P ED+K A + TS ++ ++ I+YI
Sbjct 1 MNSLSTSAFSPVAFSLGLLLVMATAFPTPERLEEDAKGDATSDKMLFTSPDKTEELIKYI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L ISA+RKE C K CE+SKE LAENNLNLPKMAEKDGCFQSGFN+ETCL++I TGL+
Sbjct 61 LGKISAMRKEMCEKYEKCENSKEVLAENNLNLPKMAEKDGCFQSGFNQETCLMRITTGLV 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EF++YL+YLQ +ES++ AVQ+STK LIQ L++K KN D TTP+PTTNA LL KLQ
Sbjct 121 EFQIYLDYLQKEYESNKGNVEAVQISTKALIQTLRQKGKNPDKATTPNPTTNAGLLDKLQ 180
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+QN+W+++ LILRS ++FLQ SLRA+R M
Sbjct 181 SQNEWMKNTKIILILRSLEDFLQFSLRAIRIM 212
>sp|Q865X6|IL6_LAMGL Interleukin-6 OS=Lama glama OX=9844 GN=IL6
PE=2 SV=1
Length=211
Score = 266 bits (679), Expect = 5e-90, Method: Compositional matrix adjust.
Identities = 127/212 (60%), Positives = 162/212 (76%), Gaps = 1/212 (0%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS STS F PVAFSLGLLLV+ AFP PVP GED KD ++P TS ++ ++ I+YI
Sbjct 1 MNSLSTSTFSPVAFSLGLLLVMATAFPTPVPLGEDFKD-GTTSKRPFTSPDKTEELIKYI 59
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L ISA+RKE C K + CE+SKEAL+ENNLNLPKM EKDGCFQSGFN+ETCL++I GLL
Sbjct 60 LGRISAMRKEMCEKYDKCENSKEALSENNLNLPKMTEKDGCFQSGFNQETCLMRITIGLL 119
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EF++YL+YLQN +E + AVQ+STK LIQ L++K K + ++TP+P T +SLL KLQ
Sbjct 120 EFQIYLDYLQNYYEGDKGNTEAVQISTKALIQLLRQKVKQPEEVSTPNPITGSSLLNKLQ 179
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+NQW+++ LILRS ++FLQ SLRA+R M
Sbjct 180 TENQWMKNTKMILILRSLEDFLQFSLRAVRIM 211
>sp|P41683|IL6_FELCA Interleukin-6 OS=Felis catus OX=9685 GN=IL6
PE=2 SV=1
Length=208
Score = 255 bits (651), Expect = 1e-85, Method: Compositional matrix adjust.
Identities = 123/212 (58%), Positives = 157/212 (74%), Gaps = 4/212 (2%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
M STSAF P+AFSLGLLLV+ AFP P P G D A +R PLTS++++++ I+YI
Sbjct 1 MTFLSTSAFSPLAFSLGLLLVVATAFPTPGPLGGD----ATSNRLPLTSADKMEELIKYI 56
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L ISAL+KE C+ N CE SKEALAENNLNLPK+AEKDGCFQSGFN+ETCL +I TGL
Sbjct 57 LGKISALKKEMCDNYNKCEDSKEALAENNLNLPKLAEKDGCFQSGFNQETCLTRITTGLQ 116
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EF++YL++LQ+++E EE A++V ST VL+Q L++K KN D +T P PT L KLQ
Sbjct 117 EFQIYLKFLQDKYEGDEENAKSVYTSTNVLLQMLKRKGKNQDEVTIPVPTVEVGLQAKLQ 176
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+Q +WL+ T HL LR ++FLQ SLRA+R M
Sbjct 177 SQEEWLRHTTIHLTLRRLEDFLQFSLRAVRIM 208
>sp|P41323|IL6_CANLF Interleukin-6 OS=Canis lupus familiaris OX=9615
GN=IL6 PE=2 SV=1
Length=207
Score = 254 bits (650), Expect = 1e-85, Method: Compositional matrix adjust.
Identities = 125/212 (59%), Positives = 159/212 (75%), Gaps = 5/212 (2%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS STSAF SLGLLLV+ AFP P P DSKD A + PLTS+ ++++ I+YI
Sbjct 1 MNSLSTSAF-----SLGLLLVMATAFPTPGPLAGDSKDDATSNSLPLTSANKVEELIKYI 55
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L ISALRKE C+K N CE SKEALAENNL+LPK+ KDGCFQSGFN+ETCL +I TGL+
Sbjct 56 LGKISALRKEMCDKFNKCEDSKEALAENNLHLPKLEGKDGCFQSGFNQETCLTRITTGLV 115
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EF+++L LQN +E +E ++V MSTK+L+Q L+ K KN D +TTPDPTT+ASL LQ
Sbjct 116 EFQLHLNILQNNYEGDKENVKSVHMSTKILVQMLKSKVKNQDEVTTPDPTTDASLQAILQ 175
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+Q++ ++ T HLILRS ++FLQ SLRA+R M
Sbjct 176 SQDECVKHTTIHLILRSLEDFLQFSLRAVRIM 207
>sp|Q9XT80|IL6_DELLE Interleukin-6 OS=Delphinapterus leucas OX=9749
GN=IL6 PE=2 SV=1
Length=208
Score = 252 bits (643), Expect = 1e-84, Method: Compositional matrix adjust.
Identities = 127/211 (60%), Positives = 155/211 (73%), Gaps = 6/211 (3%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS ST +AFSLGLLLV AFP P P GED KD R LTS ++ + I+YI
Sbjct 1 MNSLST-----IAFSLGLLLVTATAFPTPGPLGEDFKDDTTSDRLLLTSPDKTEALIKYI 55
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L ISA+RKE C K + CE+SKEALAENNLNLPKMAEKDGCFQSGFN+ETCL++I TGLL
Sbjct 56 LGKISAMRKEMCEKYDKCENSKEALAENNLNLPKMAEKDGCFQSGFNQETCLMRITTGLL 115
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
E+++YL+YLQN +E + AVQ+S K L Q L++K KN D +TTPDPTTNASL+ LQ
Sbjct 116 EYQIYLDYLQNEYEGDKGSIEAVQISIKALAQILRQKVKNPDEVTTPDPTTNASLMNNLQ 175
Query 181 AQN-QWLQDMTTHLILRSFKEFLQSSLRALR 210
+QN W+++ LILRS + FLQ SLRA+R
Sbjct 176 SQNDDWMRNTKIILILRSLENFLQFSLRAVR 206
>sp|Q28747|IL6_ORCOR Interleukin-6 (Fragment) OS=Orcinus orca
OX=9733 GN=IL6 PE=2 SV=1
Length=205
Score = 251 bits (640), Expect = 4e-84, Method: Compositional matrix adjust.
Identities = 123/199 (62%), Positives = 151/199 (76%), Gaps = 1/199 (1%)
Query 13 AFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETC 72
AFSLGLLLV AFP P P GED KD R LTS ++ + I+YIL ISA+RKE C
Sbjct 5 AFSLGLLLVTATAFPTPGPLGEDFKDDTTSDRLYLTSPDKTEALIKYILGKISAMRKEMC 64
Query 73 NKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNR 132
K + CE+SKEALAENNLNLPKMAEKDGCFQSGFN+ETCL++I TGLLE+++YL+YLQN
Sbjct 65 EKYDKCENSKEALAENNLNLPKMAEKDGCFQSGFNQETCLMRITTGLLEYQIYLDYLQNE 124
Query 133 FESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQN-QWLQDMTT 191
+E +E AVQ+S+K L Q L++K KN D +TTPDPTTNASL+ LQ+QN W+++
Sbjct 125 YEGDKEAIEAVQISSKALAQILRQKVKNPDEVTTPDPTTNASLMNNLQSQNDDWMKNTKI 184
Query 192 HLILRSFKEFLQSSLRALR 210
LILRS + FLQ SLRA+R
Sbjct 185 ILILRSLENFLQFSLRAIR 203
>sp|A3FBE9|IL6_MUSPF Interleukin-6 OS=Mustela putorius furo OX=9669
GN=IL6 PE=2 SV=1
Length=210
Score = 249 bits (637), Expect = 1e-83, Method: Compositional matrix adjust.
Identities = 124/212 (58%), Positives = 161/212 (76%), Gaps = 2/212 (1%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS STSAF PVAFSLGLLLV+ AFP P P G DSKD A +R PLTS+++++ IR+I
Sbjct 1 MNSLSTSAFSPVAFSLGLLLVMATAFPTPGPLGGDSKDDATSNRPPLTSADKMEDFIRFI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L ISAL+KE C K N CE SKEALAENNLNLPK+AE+D CFQS FN+ETCL +I TGL
Sbjct 61 LGKISALKKEMCEKYNKCEDSKEALAENNLNLPKLAEEDKCFQSQFNQETCLTRITTGLQ 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EF+++L+YL+ +E ++ A +V +STK L+Q L + N +TTPDPTT++SL +
Sbjct 121 EFQIHLKYLEANYEGNKNNAHSVYISTKHLLQKL--RPMNRVEVTTPDPTTDSSLQALFK 178
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+Q++WL+ +T HLILRS ++FLQ SLRA+R M
Sbjct 179 SQDKWLKHVTIHLILRSLEDFLQFSLRAIRIM 210
>sp|Q28819|IL6_PHOVI Interleukin-6 (Fragment) OS=Phoca vitulina
OX=9720 GN=IL6 PE=2 SV=1
Length=209
Score = 246 bits (627), Expect = 4e-82, Method: Compositional matrix adjust.
Identities = 127/207 (61%), Positives = 163/207 (79%), Gaps = 0/207 (0%)
Query 6 TSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGIS 65
TSAF PVAFSLGLLLV+ AFP P P G +S+ A +R PLTS +++++ I+YIL IS
Sbjct 3 TSAFSPVAFSLGLLLVMATAFPTPGPVGGESQADATSNRPPLTSPDKMEEFIKYILGKIS 62
Query 66 ALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVY 125
ALRKE C+K N CE SKEALAENNL LPK+AEKDGCFQSGFN+ETCL +I TGLLEF+++
Sbjct 63 ALRKEMCDKYNKCEDSKEALAENNLRLPKLAEKDGCFQSGFNQETCLTRITTGLLEFQIH 122
Query 126 LEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQW 185
L+Y+Q +E ++E A +V +STK+L+Q L KK K+ D +TTPDPTT+ SL L+AQ++W
Sbjct 123 LKYIQANYEGNKEDANSVYISTKLLVQMLMKKVKSQDEVTTPDPTTDTSLQAILKAQDKW 182
Query 186 LQDMTTHLILRSFKEFLQSSLRALRQM 212
L+ T HLILRS ++FLQ SLRA+R M
Sbjct 183 LKHTTIHLILRSLEDFLQFSLRAVRIM 209
>sp|Q25BC2|IL6_VULVU Interleukin-6 OS=Vulpes vulpes OX=9627 GN=IL6
PE=2 SV=1
Length=207
Score = 237 bits (604), Expect = 1e-78, Method: Compositional matrix adjust.
Identities = 127/212 (60%), Positives = 159/212 (75%), Gaps = 5/212 (2%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS STSAF SLGLLLV+ AFP P P DSKD A PLTS+ ++++ I+YI
Sbjct 1 MNSLSTSAF-----SLGLLLVMATAFPTPGPLAGDSKDDATSISLPLTSANKVEELIKYI 55
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L ISALRKE C+K N CE SKEALAENNL+LP + KDGCFQSGFN+ETCL +I TGL+
Sbjct 56 LGKISALRKEMCDKFNKCEDSKEALAENNLHLPILEGKDGCFQSGFNQETCLTRITTGLM 115
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EF+++L LQN +E +E A++V MSTK+L+Q L+ K KN D +TTPDPTT+A+L LQ
Sbjct 116 EFQLHLNILQNNYEGDKENAQSVHMSTKILVQMLKSKVKNQDEVTTPDPTTDATLQAILQ 175
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+QN+WL+ T HLILRS ++FLQ SLRA+R M
Sbjct 176 SQNEWLKHTTIHLILRSLEDFLQFSLRAVRIM 207
>sp|Q28319|IL6_CAPHI Interleukin-6 OS=Capra hircus OX=9925 GN=IL6
PE=2 SV=1
Length=208
Score = 227 bits (578), Expect = 1e-74, Method: Compositional matrix adjust.
Identities = 112/210 (53%), Positives = 149/210 (71%), Gaps = 4/210 (2%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS TSAF P+A SLGLLLV+ +AFP P P GED K+ P R LT+ E+ + I++I
Sbjct 1 MNSLFTSAFSPLAVSLGLLLVMTSAFPTPGPLGEDFKNDTTPSRLLLTTPEKTEALIKHI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
+D ISA+RKE C K++ CE+SKE LAEN L LPKM EKDGCFQSGFN+ CL+K GLL
Sbjct 61 VDKISAIRKEICEKNDECENSKETLAENKLKLPKMEEKDGCFQSGFNQAICLIKTTAGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
E+++YL++LQN FE ++E +Q S + LIQ L++K L ITT P TN +L K+Q
Sbjct 121 EYQIYLDFLQNEFEGNQETVMELQSSIRTLIQILKEKIAGL--ITT--PATNTDMLEKMQ 176
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALR 210
+ N+W+++ +ILRS + FLQ SLRA+R
Sbjct 177 SSNEWVKNAKVIIILRSLENFLQFSLRAIR 206
>sp|P26892|IL6_BOVIN Interleukin-6 OS=Bos taurus OX=9913 GN=IL6
PE=2 SV=1
Length=208
Score = 225 bits (574), Expect = 4e-74, Method: Compositional matrix adjust.
Identities = 112/210 (53%), Positives = 149/210 (71%), Gaps = 4/210 (2%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS TSAF P A SLGLLLV+ +AFP P P GED K+ P R LT+ E+ + I+ +
Sbjct 1 MNSRFTSAFTPFAVSLGLLLVMTSAFPTPGPLGEDFKNDTTPGRLLLTTPEKTEALIKRM 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
+D ISA+RKE C K++ CESSKE LAEN LNLPKM EKDGCFQSGFN+ CL++ GLL
Sbjct 61 VDKISAMRKEICEKNDECESSKETLAENKLNLPKMEEKDGCFQSGFNQAICLIRTTAGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
E+++YL+YLQN +E ++E R ++ + + LIQ L++K D ITT P TN LL K+Q
Sbjct 121 EYQIYLDYLQNEYEGNQENVRDLRKNIRTLIQILKQKIA--DLITT--PATNTDLLEKMQ 176
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALR 210
+ N+W+++ LILR+ + FLQ SLRA+R
Sbjct 177 SSNEWVKNAKIILILRNLENFLQFSLRAIR 206
>sp|P29455|IL6_SHEEP Interleukin-6 OS=Ovis aries OX=9940 GN=IL6
PE=2 SV=2
Length=208
Score = 225 bits (573), Expect = 7e-74, Method: Compositional matrix adjust.
Identities = 111/210 (53%), Positives = 149/210 (71%), Gaps = 4/210 (2%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS TSAF P+A SLGLLLV+ +AFP P P GED K+ P R LT+ E+ + I++I
Sbjct 1 MNSLFTSAFSPLAVSLGLLLVMTSAFPTPGPLGEDFKNDTTPSRLLLTTPEKTEALIKHI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
+D ISA+RKE C K++ CE+SKE LAEN L LPKM EKDGCFQSGFN+ CL+K GLL
Sbjct 61 VDKISAIRKEICEKNDECENSKETLAENKLKLPKMEEKDGCFQSGFNQAICLIKTTAGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
E+++YL++LQN FE ++E +Q S + LIQ L++K L ITT P T+ +L K+Q
Sbjct 121 EYQIYLDFLQNEFEGNQETVMELQSSIRTLIQILKEKIAGL--ITT--PATHTDMLEKMQ 176
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALR 210
+ N+W+++ +ILRS + FLQ SLRA+R
Sbjct 177 SSNEWVKNAKVIIILRSLENFLQFSLRAIR 206
>sp|Q2MH06|IL6_BUBCA Interleukin-6 OS=Bubalus carabanensis OX=346063
GN=IL6 PE=2 SV=1
Length=208
Score = 224 bits (570), Expect = 2e-73, Method: Compositional matrix adjust.
Identities = 111/210 (53%), Positives = 148/210 (70%), Gaps = 4/210 (2%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS TSAF P A SLGLLLV+ +AFP P P GED K+ P R LT+ E+ + I+ +
Sbjct 1 MNSRFTSAFTPFAVSLGLLLVMTSAFPTPGPLGEDFKNDTTPGRLLLTTPEKTEALIKRM 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
+D ISA+RKE C K++ CESSK+ LAEN LNLPKM EKDGCFQSGFN+ CL++ GLL
Sbjct 61 VDKISAMRKEICEKNDECESSKDTLAENKLNLPKMEEKDGCFQSGFNQAICLIRTTAGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
E+++YL+YLQN +E + E R ++ + + LIQ L++K D ITT P TN LL K+Q
Sbjct 121 EYQIYLDYLQNEYEGNRENVRDLRKNIRTLIQILKQKIA--DLITT--PATNTDLLEKMQ 176
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALR 210
+ N+W+++ LILR+ + FLQ SLRA+R
Sbjct 177 SSNEWVKNAKIILILRNLENFLQFSLRAIR 206
>sp|Q6V919|IL6_BUBBU Interleukin-6 OS=Bubalus bubalis OX=89462
GN=IL6 PE=2 SV=1
Length=208
Score = 224 bits (570), Expect = 2e-73, Method: Compositional matrix adjust.
Identities = 111/210 (53%), Positives = 148/210 (70%), Gaps = 4/210 (2%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS TSAF P A SLGLLLV+ +AFP P P GED K+ P R LT+ E+ + I+ +
Sbjct 1 MNSRFTSAFTPFAVSLGLLLVMTSAFPTPGPLGEDFKNDTTPGRLLLTTPEKTEALIKRM 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
+D ISA+RKE C K++ CESSK+ LAEN LNLPKM EKDGCFQSGFN+ CL++ GLL
Sbjct 61 VDKISAMRKEICEKNDECESSKDTLAENKLNLPKMEEKDGCFQSGFNQAICLIRTTAGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
E+++YL+YLQN +E + E R ++ + + LIQ L++K D ITT P TN LL K+Q
Sbjct 121 EYQIYLDYLQNEYEGNRENVRDLRKNIRTLIQILKQKIA--DLITT--PATNTDLLEKMQ 176
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALR 210
+ N+W+++ LILR+ + FLQ SLRA+R
Sbjct 177 SSNEWVKNAKIILILRNLENFLQFSLRAIR 206
>sp|O35736|IL6_MARMO Interleukin-6 OS=Marmota monax OX=9995 GN=IL6
PE=2 SV=1
Length=207
Score = 191 bits (484), Expect = 2e-60, Method: Compositional matrix adjust.
Identities = 93/199 (47%), Positives = 134/199 (67%), Gaps = 2/199 (1%)
Query 15 SLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNK 74
SLGLLLV+ AFPA ED ++ ++ SS + +QI Y++ + +RKE C
Sbjct 8 SLGLLLVVATAFPASELQREDGENSVTRNKPTRASSGKTRRQISYLIKEVFEMRKELCKN 67
Query 75 SNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFE 134
C S A++ENNLNLPKM EKDGCFQ+G+N + CLV+I +GLLEF+VYL Y++N+F+
Sbjct 68 DETCIKSHVAVSENNLNLPKMTEKDGCFQTGYNRDDCLVRITSGLLEFQVYLRYIRNKFQ 127
Query 135 SSEEQARA--VQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTH 192
+ RA VQ S+K LI+ L+++ K+ + I P PT N +LL KL++QN W + MT
Sbjct 128 EGNNRDRAEHVQSSSKALIEILKQEVKDPNKIVFPSPTANINLLAKLESQNDWQKVMTMQ 187
Query 193 LILRSFKEFLQSSLRALRQ 211
LIL +F++FLQ +LRA+R+
Sbjct 188 LILSNFEDFLQFTLRAVRK 206
>sp|Q9MZR1|IL6_RABIT Interleukin-6 OS=Oryctolagus cuniculus OX=9986
GN=IL6 PE=2 SV=1
Length=241
Score = 178 bits (452), Expect = 3e-55, Method: Compositional matrix adjust.
Identities = 102/216 (47%), Positives = 132/216 (61%), Gaps = 6/216 (3%)
Query 1 MNSFSTSAF--GPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIR 58
MNSF TSA GP+ SL LLLV+ AFP P EDS A+P + LT R + IR
Sbjct 1 MNSF-TSALRPGPLGCSLALLLVVATAFPTSAPVREDSNTKASPDKT-LTPPGRTIESIR 58
Query 59 YILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITG 118
IL+ I LRKE C+ C + KEALAE NL+LP++ E+DGCF N ETCL++I +G
Sbjct 59 SILETIKELRKEMCDHDVNCMNRKEALAEVNLHLPRLIEEDGCFPPAVNNETCLLRITSG 118
Query 119 LLEFEVYLEYLQNRFESSEEQARA--VQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLL 176
L+EF +YLE+LQ +F S EE R V + + LI+ L+ K KNL+ T P SL+
Sbjct 119 LMEFRMYLEHLQAKFRSDEENTRVSMVLKNIQHLIKTLRPKVKNLNEEATLKPAVAVSLM 178
Query 177 TKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
LQ +NQWL+ T H ILR FL+ +LRA+ M
Sbjct 179 ENLQQKNQWLKTTTIHFILRGLTNFLEFTLRAVDLM 214
>sp|P20607|IL6_RAT Interleukin-6 OS=Rattus norvegicus OX=10116
GN=Il6 PE=2 SV=1
Length=211
Score = 175 bits (444), Expect = 2e-54, Method: Compositional matrix adjust.
Identities = 87/213 (41%), Positives = 142/213 (67%), Gaps = 5/213 (2%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFP-APVPPGEDSKDVAAPHRQPLTSSERIDKQIRY 59
M S F PVAF LGL+L+ AFP + V G+ ++D H +P+ ++ ++ I Y
Sbjct 1 MKFLSARDFQPVAF-LGLMLLTATAFPTSQVRRGDFTEDTT--HNRPVYTTSQVGGLITY 57
Query 60 ILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGL 119
+L I +RKE CN ++ C +S +AL+ENNL LP++ DGCFQ+G+N+E CL+KI +GL
Sbjct 58 VLREILEMRKELCNGNSDCMNSDDALSENNLKLPEIQRNDGCFQTGYNQEICLLKICSGL 117
Query 120 LEFEVYLEYLQNRF-ESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTK 178
LEF YLE+++N ++ +++AR +Q +T+ L+ +++ K+ I P PT+NA L+ K
Sbjct 118 LEFRFYLEFVKNNLQDNKKDKARVIQSNTETLVHIFKQEIKDSYKIVLPTPTSNALLMEK 177
Query 179 LQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQ 211
L++Q +WL+ T LIL++ +EFL+ ++R+ RQ
Sbjct 178 LESQKEWLRTKTIQLILKALEEFLKVTMRSTRQ 210
>sp|P08505|IL6_MOUSE Interleukin-6 OS=Mus musculus OX=10090 GN=Il6
PE=1 SV=1
Length=211
Score = 172 bits (436), Expect = 4e-53, Method: Compositional matrix adjust.
Identities = 87/212 (41%), Positives = 134/212 (63%), Gaps = 3/212 (1%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
M S F PVAF LGL+LV AFP D + P+R P+ ++ ++ I ++
Sbjct 1 MKFLSARDFHPVAF-LGLMLVTTTAFPTSQVRRGDFTEDTTPNR-PVYTTSQVGGLITHV 58
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L I +RKE CN ++ C ++ +ALAENNL LP++ DGC+Q+G+N+E CL+KI +GLL
Sbjct 59 LWEIVEMRKELCNGNSDCMNNDDALAENNLKLPEIQRNDGCYQTGYNQEICLLKISSGLL 118
Query 121 EFEVYLEYLQNRF-ESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKL 179
E+ YLEY++N ++ +++AR +Q T+ LI ++ K+L I P P +NA L KL
Sbjct 119 EYHSYLEYMKNNLKDNKKDKARVLQRDTETLIHIFNQEVKDLHKIVLPTPISNALLTDKL 178
Query 180 QAQNQWLQDMTTHLILRSFKEFLQSSLRALRQ 211
++Q +WL+ T IL+S +EFL+ +LR+ RQ
Sbjct 179 ESQKEWLRTKTIQFILKSLEEFLKVTLRSTRQ 210
>sp|P41693|IL6_NEOVI Interleukin-6 (Fragment) OS=Neovison vison
OX=452646 GN=IL6 PE=2 SV=1
Length=125
Score = 139 bits (349), Expect = 5e-41, Method: Compositional matrix adjust.
Identities = 67/127 (53%), Positives = 96/127 (76%), Gaps = 2/127 (2%)
Query 86 AENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQM 145
AENNL LPK+AEKD CFQS FN+ETC+ +I TGL EF+++L+YL+ +E ++ A +V +
Sbjct 1 AENNLKLPKLAEKDKCFQSQFNQETCMTRITTGLQEFQIHLKYLEANYEGNKNNAHSVYI 60
Query 146 STKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSS 205
STK L+Q L + N +TTP+PTT++SL ++Q++WL+ +T HLILRS ++FLQ S
Sbjct 61 STKHLLQKL--RPMNQVEVTTPNPTTDSSLQALFKSQDKWLKHVTIHLILRSLEDFLQFS 118
Query 206 LRALRQM 212
LRA+R M
Sbjct 119 LRAIRIM 125
>sp|Q90YI0|IL6_CHICK Interleukin-6 OS=Gallus gallus OX=9031 GN=IL6
PE=2 SV=1
Length=241
Score = 135 bits (341), Expect = 2e-38, Method: Compositional matrix adjust.
Identities = 68/180 (38%), Positives = 105/180 (58%), Gaps = 3/180 (2%)
Query 33 GEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNL 92
GE + A R+ L E + + +R D L+ E C K +CE+S E L NNLNL
Sbjct 57 GEVGLEEEAGARRALLDCEPLARVLR---DRAVQLQDEMCKKFTVCENSMEMLVRNNLNL 113
Query 93 PKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQ 152
PK+ E+DGC +GF+EE CL K+ +GL F+ YLE++Q F+S ++ ++ STK L
Sbjct 114 PKVTEEDGCLLAGFDEEKCLTKLSSGLFAFQTYLEFIQETFDSEKQNVESLCYSTKHLAA 173
Query 153 FLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+++ N D + PD SLL L++ W++ +T HLILR F F++ ++RA+R +
Sbjct 174 TIRQMVINPDEVVIPDSAAQKSLLANLKSDKDWIEKITMHLILRDFTSFMEKTVRAVRYL 233
>sp|Q2HRC7|VIL6_HHV8P Viral interleukin-6 homolog OS=Human herpesvirus
8 type P (isolate GK18) OX=868565 GN=K2 PE=1 SV=1
Length=204
Score = 78.2 bits (191), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 41/158 (26%), Positives = 77/158 (49%), Gaps = 0/158 (0%)
Query 55 KQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVK 114
+++ ++L I ++ C ++ +C+ E A +L LP + + D C GFNE +CL K
Sbjct 37 QRLNWMLWVIDECFRDLCYRTGICKGILEPAAIFHLKLPAINDTDHCGLIGFNETSCLKK 96
Query 115 IITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNAS 174
+ G EFEV ++L F S +++ TK L +Q++ L P +
Sbjct 97 LADGFFEFEVLFKFLTTEFGKSVINVDVMELLTKTLGWDIQEELNKLTKTHYSPPKFDRG 156
Query 175 LLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
LL +LQ W++ + +L + ++F ++R L +
Sbjct 157 LLGRLQGLKYWVRHFASFYVLSAMEKFAGQAVRVLNSI 194
>sp|A0S0B0|IL6_PAROL Interleukin-6 OS=Paralichthys olivaceus OX=8255
GN=il6 PE=2 SV=1
Length=230
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 29/111 (26%), Positives = 55/111 (50%), Gaps = 1/111 (1%)
Query 101 CFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKN 160
C + F++E CL ++ GL + V ++++ + SS A + + LI +++K +N
Sbjct 96 CPSANFSKEACLQRLAEGLHTYMVLFKHVEKEYPSSSILLHA-RYHSGALIGLIKEKMRN 154
Query 161 LDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQ 211
+T P LL + + + + MT H ILR FL++ A+R+
Sbjct 155 PGQVTVPTSRQEQQLLQDMDNPSTFHRKMTAHNILRQLHNFLRNGKVAIRK 205
>sp|P13854|MGF_CHICK Myelomonocytic growth factor OS=Gallus gallus
OX=9031 PE=2 SV=1
Length=201
Score = 48.5 bits (114), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 37/155 (24%), Positives = 67/155 (43%), Gaps = 3/155 (2%)
Query 58 RYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIIT 117
R I ++AL++ C+ +C + L + + +L + A D C + GF E C +I
Sbjct 47 RKIRGDVAALQRAVCDTFQLCTEEELQLVQPDPHLVQ-APLDQCHKRGFQAEVCFTQIRA 105
Query 118 GLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLT 177
GL + L + + +Q+ L +Q++ ++L T P S
Sbjct 106 GLHAYHDSLGAVLRLLPNHTTLVETLQLDAANLSSNIQQQMEDLGLDTVTLPAEQRSPPP 165
Query 178 KLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
Q Q + IL +F+ FL+++ RALR +
Sbjct 166 TFSGPFQ--QQVGGFFILANFQRFLETAYRALRHL 198
>sp|Q0GGL7|IL6_ONCMY Interleukin-6 OS=Oncorhynchus mykiss OX=8022
GN=il6 PE=2 SV=1
Length=219
Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 29/109 (27%), Positives = 55/109 (50%), Gaps = 1/109 (1%)
Query 104 SGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDA 163
S N+E CL +I GL +++ L++++ + S +V T VLI ++ + K +
Sbjct 104 SASNKEACLQEISRGLQVYQLLLQHVKAEYPQST-LLPSVTHQTTVLIGLVKDQMKVAEV 162
Query 164 ITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+ + +L ++ +W + + H ILR + FL + RALR+M
Sbjct 163 VEDLSASERKRVLGEVSTGTEWERKTSVHAILRELRNFLVDTKRALRRM 211
>sp|Q6L6X6|IL6_TAKRU Interleukin-6 OS=Takifugu rubripes OX=31033
GN=il6 PE=2 SV=1
Length=227
Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 31/124 (25%), Positives = 59/124 (48%), Gaps = 3/124 (2%)
Query 88 NNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMST 147
+ +P + K C S F ++ CL +++ GLL + V L+ ++ F SS + V+ +
Sbjct 82 DRYKIPSLPAK--CPYSNFGKDACLRRLLEGLLIYSVLLKRVEEEFPSSSILSE-VRFYS 138
Query 148 KVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLR 207
+LI+ L+ K ++ D + + LL + + + MT H IL + FL R
Sbjct 139 NILIKELENKVRDRDQVMRLTSSQEEQLLKDTDYPDTFHRKMTAHGILYNLHYFLVDCRR 198
Query 208 ALRQ 211
+ +
Sbjct 199 VINK 202
>sp|P09920|CSF3_MOUSE Granulocyte colony-stimulating factor OS=Mus
musculus OX=10090 GN=Csf3 PE=1 SV=1
Length=208
Score = 40.8 bits (94), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 27/119 (23%), Positives = 51/119 (43%), Gaps = 1/119 (1%)
Query 55 KQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVK 114
+Q+R I S L ++ C +C + L ++L +PK A GC + CL +
Sbjct 55 EQVRKIQASGSVLLEQLCATYKLCHPEELVLLGHSLGIPK-ASLSGCSSQALQQTQCLSQ 113
Query 115 IITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNA 173
+ +GL ++ L+ L + +Q+ + ++ +NL T PT +A
Sbjct 114 LHSGLCLYQGLLQALSGISPALAPTLDLLQLDVANFATTIWQQMENLGVAPTVQPTQSA 172
>sp|O18739|CCN2_BOVIN CCN family member 2 OS=Bos taurus OX=9913
GN=CCN2 PE=2 SV=2
Length=349
Score = 34.7 bits (78), Expect = 0.44, Method: Compositional matrix adjust.
Identities = 28/107 (26%), Positives = 42/107 (39%), Gaps = 17/107 (16%)
Query 4 FSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDG 63
S + GPV + LLL L + PA S+D +AP + P + R + +LDG
Sbjct 1 MSATGLGPVRCAFVLLLAL-CSRPA------SSQDCSAPCQCPAGPAPRCPAGVSLVLDG 53
Query 64 ISALR------KETCNKSNMCESSKEALAE----NNLNLPKMAEKDG 100
R E C + + C+ K + N + KDG
Sbjct 54 CGCCRVCAKQLSELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDG 100
>sp|Q0A783|NUOI_ALKEH NADH-quinone oxidoreductase subunit I OS=Alkalilimnicola
ehrlichii (strain ATCC BAA-1101 / DSM 17681
/ MLHE-1) OX=187272 GN=nuoI PE=3 SV=1
Length=163
Score = 34.3 bits (77), Expect = 0.46, Method: Compositional matrix adjust.
Identities = 27/88 (31%), Positives = 37/88 (42%), Gaps = 20/88 (23%)
Query 63 GISALRK-----ETCNKSNMCESSKEALAENNLNLPKMAEKDG-------------CFQS 104
G+ ALR+ E C +CE+ ALA P+ E DG C
Sbjct 49 GMHALRRYPNGEERCIACKLCEAVCPALAITIEAGPR--EDDGTRRTTLYEIDMFKCIYC 106
Query 105 GFNEETCLVKIITGLLEFEVYLEYLQNR 132
GF EE+C V I E E ++E+ + R
Sbjct 107 GFCEESCPVDSIVETREHEYHMEHREER 134
>sp|Q8TXI4|RAD50_METKA DNA double-strand break repair Rad50 ATPase
OS=Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM
9639 / NBRC 100938) OX=190192 GN=rad50 PE=3 SV=1
Length=876
Score = 33.5 bits (75), Expect = 1.3, Method: Composition-based stats.
Identities = 30/114 (26%), Positives = 52/114 (46%), Gaps = 4/114 (4%)
Query 31 PPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNL 90
P E+ K+ R+ ER++ ++R + + I +L+ + + E KEA E
Sbjct 220 PEVEELKERLNELREAKREFERLEGELRLLENKIESLKGRRDDLRKLVEEGKEAERE--- 276
Query 91 NLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQ 144
L ++ + + NEE L + I L L L+NR ES+EE+ V+
Sbjct 277 -LQRLGDVPSKVRELENEEAELRRRIEELRNLLDDLRSLRNRLESAEEELEGVK 329
>sp|Q2NV92|EX7S_SODGM Exodeoxyribonuclease 7 small subunit OS=Sodalis
glossinidius (strain morsitans) OX=343509 GN=xseB PE=3
SV=1
Length=82
Score = 30.0 bits (66), Expect = 4.8, Method: Compositional matrix adjust.
Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 3/64 (5%)
Query 92 LPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLI 151
+PK AEK F++ E L +I+T L E+ LE N FE + AR Q + +
Sbjct 1 MPKKAEKPASFETALKE---LEQIVTRLESGELPLEQALNEFEQGVQLARQGQKTLQQAE 57
Query 152 QFLQ 155
Q +Q
Sbjct 58 QRVQ 61
>sp|C6DB39|EX7S_PECCP Exodeoxyribonuclease 7 small subunit OS=Pectobacterium
carotovorum subsp. carotovorum (strain PC1) OX=561230
GN=xseB PE=3 SV=1
Length=82
Score = 29.6 bits (65), Expect = 6.3, Method: Compositional matrix adjust.
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 10/86 (12%)
Query 92 LPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLI 151
+PK E+ F+S NE L KI+T L E+ L+ N FE + AR Q
Sbjct 1 MPKKTEQPVSFESSLNE---LEKIVTRLESGELPLDDALNEFEHGIQLARQGQ------- 50
Query 152 QFLQKKAKNLDAITTPDPTTNASLLT 177
Q LQ+ + + + + DP S T
Sbjct 51 QKLQQAEQRVQILLSDDPDAPLSPFT 76
>sp|O02708|CSF3_FELCA Granulocyte colony-stimulating factor (Fragment)
OS=Felis catus OX=9685 GN=CSF3 PE=2 SV=1
Length=194
Score = 30.8 bits (68), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 17/75 (23%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query 55 KQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVK 114
+Q+R + +AL++ C +C + L + L +P+ A C CL +
Sbjct 39 EQVRKVQADGTALQERLCAAHKLCHPEELVLLGHALGIPQ-APLSSCSSQALQLTGCLRQ 97
Query 115 IITGLLEFEVYLEYL 129
+ +GL ++ L+ L
Sbjct 98 LHSGLFLYQGLLQAL 112
>sp|Q6D842|EX7S_PECAS Exodeoxyribonuclease 7 small subunit OS=Pectobacterium
atrosepticum (strain SCRI 1043 / ATCC BAA-672)
OX=218491 GN=xseB PE=3 SV=1
Length=82
Score = 29.6 bits (65), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 10/86 (12%)
Query 92 LPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLI 151
+PK E+ F+S NE L KI+T L E+ L+ N FE + AR Q
Sbjct 1 MPKKTEQPVSFESSLNE---LEKIVTRLESGELPLDDALNEFEHGIQLARQGQ------- 50
Query 152 QFLQKKAKNLDAITTPDPTTNASLLT 177
Q LQ+ + + + + DP S T
Sbjct 51 QKLQQAEQRVQILLSDDPDAPLSPFT 76
>sp|P44647|PRIA_HAEIN Primosomal protein N' OS=Haemophilus influenzae
(strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421
GN=priA PE=3 SV=1
Length=730
Score = 31.6 bits (70), Expect = 6.9, Method: Compositional matrix adjust.
Identities = 20/56 (36%), Positives = 31/56 (55%), Gaps = 5/56 (9%)
Query 86 AENNLNLPK---MAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEE 138
AEN L L K +A F SGFN L+ +TG + E+YL+Y++ +S ++
Sbjct 195 AENRLTLNKQQALAFSQLLFHSGFN--VWLLDGVTGSGKTEIYLQYIEEILKSGKQ 248
>sp|P06668|VIRD2_RHIRD T-DNA border endonuclease VirD2 OS=Rhizobium
radiobacter OX=358 GN=virD2 PE=1 SV=1
Length=424
Score = 30.8 bits (68), Expect = 9.5, Method: Compositional matrix adjust.
Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 8/50 (16%)
Query 154 LQKKAKNLDAITTPDP--------TTNASLLTKLQAQNQWLQDMTTHLIL 195
LQ+ A++LD PD T A + + Q+ + QD+TTH+I+
Sbjct 38 LQRSARHLDIPVPPDQIRELAQSWVTEAGIYDESQSDDDRQQDLTTHIIV 87
Lambda K H a alpha
0.316 0.130 0.363 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 14070229470
Results from round 2
Query= sp|P05231|IL6_HUMAN Interleukin-6 OS=Homo sapiens OX=9606 GN=IL6
PE=1 SV=1
Length=212
Score E
Sequences producing significant alignments: (Bits) Value
Sequences used in model and found again:
sp|P26893|IL6_PIG Interleukin-6 OS=Sus scrofa OX=9823 GN=IL6 PE=2... 334 6e-117
sp|Q865W7|IL6_CAMBA Interleukin-6 OS=Camelus bactrianus OX=9837 G... 331 7e-116
sp|Q865X6|IL6_LAMGL Interleukin-6 OS=Lama glama OX=9844 GN=IL6 PE... 328 1e-114
sp|Q9XT80|IL6_DELLE Interleukin-6 OS=Delphinapterus leucas OX=974... 327 3e-114
sp|A3FBE9|IL6_MUSPF Interleukin-6 OS=Mustela putorius furo OX=966... 326 1e-113
sp|Q28747|IL6_ORCOR Interleukin-6 (Fragment) OS=Orcinus orca OX=9... 321 6e-112
sp|P41683|IL6_FELCA Interleukin-6 OS=Felis catus OX=9685 GN=IL6 P... 321 8e-112
sp|P79341|IL6_MACFA Interleukin-6 OS=Macaca fascicularis OX=9541 ... 318 1e-110
sp|Q5I6E3|IL6_MACTH Interleukin-6 OS=Macaca thibetana OX=54602 GN... 318 2e-110
sp|P41323|IL6_CANLF Interleukin-6 OS=Canis lupus familiaris OX=96... 317 3e-110
sp|Q28819|IL6_PHOVI Interleukin-6 (Fragment) OS=Phoca vitulina OX... 317 5e-110
sp|Q8MKH0|IL6_SAISC Interleukin-6 OS=Saimiri sciureus OX=9521 GN=... 317 5e-110
sp|P51494|IL6_MACMU Interleukin-6 OS=Macaca mulatta OX=9544 GN=IL... 316 7e-110
sp|P46650|IL6_CERAT Interleukin-6 OS=Cercocebus atys OX=9531 GN=I... 316 1e-109
sp|Q95181|IL6_HORSE Interleukin-6 OS=Equus caballus OX=9796 GN=IL... 310 1e-107
sp|P05231|IL6_HUMAN Interleukin-6 OS=Homo sapiens OX=9606 GN=IL6 ... 302 2e-104
sp|Q25BC2|IL6_VULVU Interleukin-6 OS=Vulpes vulpes OX=9627 GN=IL6... 300 2e-103
sp|P26892|IL6_BOVIN Interleukin-6 OS=Bos taurus OX=9913 GN=IL6 PE... 296 3e-102
sp|Q2MH06|IL6_BUBCA Interleukin-6 OS=Bubalus carabanensis OX=3460... 296 5e-102
sp|Q6V919|IL6_BUBBU Interleukin-6 OS=Bubalus bubalis OX=89462 GN=... 296 5e-102
sp|Q28319|IL6_CAPHI Interleukin-6 OS=Capra hircus OX=9925 GN=IL6 ... 291 3e-100
sp|P29455|IL6_SHEEP Interleukin-6 OS=Ovis aries OX=9940 GN=IL6 PE... 290 9e-100
sp|P08505|IL6_MOUSE Interleukin-6 OS=Mus musculus OX=10090 GN=Il6... 269 3e-91
sp|P20607|IL6_RAT Interleukin-6 OS=Rattus norvegicus OX=10116 GN=... 259 2e-87
sp|O35736|IL6_MARMO Interleukin-6 OS=Marmota monax OX=9995 GN=IL6... 257 1e-86
sp|Q9MZR1|IL6_RABIT Interleukin-6 OS=Oryctolagus cuniculus OX=998... 253 2e-84
sp|Q90YI0|IL6_CHICK Interleukin-6 OS=Gallus gallus OX=9031 GN=IL6... 211 6e-68
sp|P41693|IL6_NEOVI Interleukin-6 (Fragment) OS=Neovison vison OX... 182 5e-58
sp|Q2HRC7|VIL6_HHV8P Viral interleukin-6 homolog OS=Human herpesv... 184 8e-58
sp|P13854|MGF_CHICK Myelomonocytic growth factor OS=Gallus gallus... 155 2e-46
sp|A0S0B0|IL6_PAROL Interleukin-6 OS=Paralichthys olivaceus OX=82... 145 2e-42
sp|Q6L6X6|IL6_TAKRU Interleukin-6 OS=Takifugu rubripes OX=31033 G... 132 2e-37
sp|Q0GGL7|IL6_ONCMY Interleukin-6 OS=Oncorhynchus mykiss OX=8022 ... 125 1e-34
Sequences not found previously or not previously below threshold:
sp|B6CKP4|IL6_SPAAU Interleukin-6 OS=Sparus aurata OX=8175 GN=il6... 99.8 1e-24
sp|P35834|CSF3_CANLF Granulocyte colony-stimulating factor OS=Can... 73.2 4e-15
sp|P09919|CSF3_HUMAN Granulocyte colony-stimulating factor OS=Hom... 73.6 6e-15
sp|P09920|CSF3_MOUSE Granulocyte colony-stimulating factor OS=Mus... 72.0 2e-14
sp|O02708|CSF3_FELCA Granulocyte colony-stimulating factor (Fragm... 71.2 4e-14
sp|O02837|CSF3_PIG Granulocyte colony-stimulating factor OS=Sus s... 66.2 2e-12
sp|P35833|CSF3_BOVIN Granulocyte colony-stimulating factor OS=Bos... 65.1 6e-12
sp|Q28746|CSF3_SHEEP Granulocyte colony-stimulating factor OS=Ovi... 61.2 1e-10
sp|Q9EQ14|IL23A_MOUSE Interleukin-23 subunit alpha OS=Mus musculu... 49.7 2e-06
sp|Q91Z84|IL23A_RAT Interleukin-23 subunit alpha OS=Rattus norveg... 47.4 1e-05
sp|Q64FU1|IL23A_HORSE Interleukin-23 subunit alpha OS=Equus cabal... 47.4 2e-05
sp|Q9NPF7|IL23A_HUMAN Interleukin-23 subunit alpha OS=Homo sapien... 38.5 0.015
sp|Q9N2H9|IL23A_PIG Interleukin-23 subunit alpha OS=Sus scrofa OX... 38.1 0.026
sp|Q6LA37|IL23A_CAVPO Interleukin-23 subunit alpha OS=Cavia porce... 37.4 0.039
sp|Q06194|FA8_MOUSE Coagulation factor VIII OS=Mus musculus OX=10... 35.8 0.33
sp|Q18237|SMC5_CAEEL Structural maintenance of chromosomes protei... 35.4 0.33
sp|Q99567|NUP88_HUMAN Nuclear pore complex protein Nup88 OS=Homo ... 33.9 0.99
sp|Q13464|ROCK1_HUMAN Rho-associated protein kinase 1 OS=Homo sap... 33.5 1.6
sp|P35978|KINH_STRPU Kinesin heavy chain OS=Strongylocentrotus pu... 33.1 1.7
sp|Q5B4E7|PPID_EMENI Peptidyl-prolyl cis-trans isomerase D OS=Eme... 32.7 2.1
sp|C4ULG3|AFP18_YERRA Toxin Afp18 OS=Yersinia ruckeri serotype O1... 33.1 2.4
sp|P70335|ROCK1_MOUSE Rho-associated protein kinase 1 OS=Mus musc... 32.7 2.6
sp|B9GE13|KN12F_ORYSJ Kinesin-like protein KIN-12F OS=Oryza sativ... 32.7 3.0
sp|P33176|KINH_HUMAN Kinesin-1 heavy chain OS=Homo sapiens OX=960... 32.3 3.5
sp|O77819|ROCK1_RABIT Rho-associated protein kinase 1 OS=Oryctola... 32.3 3.7
sp|Q83BT4|NRDR_COXBU Transcriptional repressor NrdR OS=Coxiella b... 31.2 3.9
sp|A9N8T7|NRDR_COXBR Transcriptional repressor NrdR OS=Coxiella b... 31.2 3.9
sp|A9KBN5|NRDR_COXBN Transcriptional repressor NrdR OS=Coxiella b... 31.2 3.9
sp|B6IZ81|NRDR_COXB2 Transcriptional repressor NrdR OS=Coxiella b... 31.2 3.9
sp|B6J8Q8|NRDR_COXB1 Transcriptional repressor NrdR OS=Coxiella b... 31.2 3.9
sp|P0CF95|BICL1_DANRE BICD family-like cargo adapter 1 OS=Danio r... 32.0 4.4
sp|P39723|MBO1_YEAST Gamma tubulin complex adapter SPC72 OS=Sacch... 31.2 7.4
sp|P61584|ROCK1_PANTR Rho-associated protein kinase 1 (Fragment) ... 31.2 8.0
sp|B0BMJ2|CC42M_XENTR Coiled-coil domain-containing protein 42 li... 30.8 9.4
>sp|P26893|IL6_PIG Interleukin-6 OS=Sus scrofa OX=9823 GN=IL6
PE=2 SV=2
Length=212
Score = 334 bits (856), Expect = 6e-117, Method: Composition-based stats.
Identities = 130/212 (61%), Positives = 162/212 (76%), Gaps = 0/212 (0%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS STSAF PVAFSLGLLLV+ AFP P ED+K A + TS ++ ++ I+YI
Sbjct 1 MNSLSTSAFSPVAFSLGLLLVMATAFPTPERLEEDAKGDATSDKMLFTSPDKTEELIKYI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L ISA+RKE C K CE+SKE LAENNLNLPKMAEKDGCFQSGFN+ETCL++I TGL+
Sbjct 61 LGKISAMRKEMCEKYEKCENSKEVLAENNLNLPKMAEKDGCFQSGFNQETCLMRITTGLV 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EF++YL+YLQ +ES++ AVQ+STK LIQ L++K KN D TTP+PTTNA LL KLQ
Sbjct 121 EFQIYLDYLQKEYESNKGNVEAVQISTKALIQTLRQKGKNPDKATTPNPTTNAGLLDKLQ 180
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+QN+W+++ LILRS ++FLQ SLRA+R M
Sbjct 181 SQNEWMKNTKIILILRSLEDFLQFSLRAIRIM 212
>sp|Q865W7|IL6_CAMBA Interleukin-6 OS=Camelus bactrianus OX=9837
GN=IL6 PE=2 SV=1
Length=211
Score = 331 bits (849), Expect = 7e-116, Method: Composition-based stats.
Identities = 129/212 (61%), Positives = 163/212 (77%), Gaps = 1/212 (0%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS STSAF PVAFSLGLLLV+ AFP PVP GED KD +R P TS ++ ++ I+YI
Sbjct 1 MNSLSTSAFSPVAFSLGLLLVMATAFPTPVPLGEDFKDGTTSNR-PFTSPDKSEELIKYI 59
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L ISA+RKE C K + CE+SKEAL+ENNLNLPKM EKDGCFQSGFN+ETCL++I GLL
Sbjct 60 LGRISAMRKEMCEKYDKCENSKEALSENNLNLPKMTEKDGCFQSGFNQETCLMRITIGLL 119
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EF++YL+YLQN +E + AVQ+STK LIQ L++K K + ++TP+P T +SLL KLQ
Sbjct 120 EFQIYLDYLQNYYEGDKGNTEAVQISTKALIQLLRQKVKQPEEVSTPNPITGSSLLNKLQ 179
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+NQW+++ LILRS ++FLQ SLRA+R M
Sbjct 180 TENQWMKNTKMILILRSLEDFLQFSLRAVRIM 211
>sp|Q865X6|IL6_LAMGL Interleukin-6 OS=Lama glama OX=9844 GN=IL6
PE=2 SV=1
Length=211
Score = 328 bits (842), Expect = 1e-114, Method: Composition-based stats.
Identities = 127/212 (60%), Positives = 162/212 (76%), Gaps = 1/212 (0%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS STS F PVAFSLGLLLV+ AFP PVP GED KD ++P TS ++ ++ I+YI
Sbjct 1 MNSLSTSTFSPVAFSLGLLLVMATAFPTPVPLGEDFKDGTTS-KRPFTSPDKTEELIKYI 59
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L ISA+RKE C K + CE+SKEAL+ENNLNLPKM EKDGCFQSGFN+ETCL++I GLL
Sbjct 60 LGRISAMRKEMCEKYDKCENSKEALSENNLNLPKMTEKDGCFQSGFNQETCLMRITIGLL 119
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EF++YL+YLQN +E + AVQ+STK LIQ L++K K + ++TP+P T +SLL KLQ
Sbjct 120 EFQIYLDYLQNYYEGDKGNTEAVQISTKALIQLLRQKVKQPEEVSTPNPITGSSLLNKLQ 179
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+NQW+++ LILRS ++FLQ SLRA+R M
Sbjct 180 TENQWMKNTKMILILRSLEDFLQFSLRAVRIM 211
>sp|Q9XT80|IL6_DELLE Interleukin-6 OS=Delphinapterus leucas OX=9749
GN=IL6 PE=2 SV=1
Length=208
Score = 327 bits (838), Expect = 3e-114, Method: Composition-based stats.
Identities = 127/212 (60%), Positives = 155/212 (73%), Gaps = 6/212 (3%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS ST +AFSLGLLLV AFP P P GED KD R LTS ++ + I+YI
Sbjct 1 MNSLST-----IAFSLGLLLVTATAFPTPGPLGEDFKDDTTSDRLLLTSPDKTEALIKYI 55
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L ISA+RKE C K + CE+SKEALAENNLNLPKMAEKDGCFQSGFN+ETCL++I TGLL
Sbjct 56 LGKISAMRKEMCEKYDKCENSKEALAENNLNLPKMAEKDGCFQSGFNQETCLMRITTGLL 115
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
E+++YL+YLQN +E + AVQ+S K L Q L++K KN D +TTPDPTTNASL+ LQ
Sbjct 116 EYQIYLDYLQNEYEGDKGSIEAVQISIKALAQILRQKVKNPDEVTTPDPTTNASLMNNLQ 175
Query 181 AQN-QWLQDMTTHLILRSFKEFLQSSLRALRQ 211
+QN W+++ LILRS + FLQ SLRA+R
Sbjct 176 SQNDDWMRNTKIILILRSLENFLQFSLRAVRI 207
>sp|A3FBE9|IL6_MUSPF Interleukin-6 OS=Mustela putorius furo OX=9669
GN=IL6 PE=2 SV=1
Length=210
Score = 326 bits (835), Expect = 1e-113, Method: Composition-based stats.
Identities = 124/212 (58%), Positives = 161/212 (76%), Gaps = 2/212 (1%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS STSAF PVAFSLGLLLV+ AFP P P G DSKD A +R PLTS+++++ IR+I
Sbjct 1 MNSLSTSAFSPVAFSLGLLLVMATAFPTPGPLGGDSKDDATSNRPPLTSADKMEDFIRFI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L ISAL+KE C K N CE SKEALAENNLNLPK+AE+D CFQS FN+ETCL +I TGL
Sbjct 61 LGKISALKKEMCEKYNKCEDSKEALAENNLNLPKLAEEDKCFQSQFNQETCLTRITTGLQ 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EF+++L+YL+ +E ++ A +V +STK L+Q L+ N +TTPDPTT++SL +
Sbjct 121 EFQIHLKYLEANYEGNKNNAHSVYISTKHLLQKLRPM--NRVEVTTPDPTTDSSLQALFK 178
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+Q++WL+ +T HLILRS ++FLQ SLRA+R M
Sbjct 179 SQDKWLKHVTIHLILRSLEDFLQFSLRAIRIM 210
>sp|Q28747|IL6_ORCOR Interleukin-6 (Fragment) OS=Orcinus orca
OX=9733 GN=IL6 PE=2 SV=1
Length=205
Score = 321 bits (823), Expect = 6e-112, Method: Composition-based stats.
Identities = 123/200 (62%), Positives = 151/200 (76%), Gaps = 1/200 (1%)
Query 13 AFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETC 72
AFSLGLLLV AFP P P GED KD R LTS ++ + I+YIL ISA+RKE C
Sbjct 5 AFSLGLLLVTATAFPTPGPLGEDFKDDTTSDRLYLTSPDKTEALIKYILGKISAMRKEMC 64
Query 73 NKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNR 132
K + CE+SKEALAENNLNLPKMAEKDGCFQSGFN+ETCL++I TGLLE+++YL+YLQN
Sbjct 65 EKYDKCENSKEALAENNLNLPKMAEKDGCFQSGFNQETCLMRITTGLLEYQIYLDYLQNE 124
Query 133 FESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQN-QWLQDMTT 191
+E +E AVQ+S+K L Q L++K KN D +TTPDPTTNASL+ LQ+QN W+++
Sbjct 125 YEGDKEAIEAVQISSKALAQILRQKVKNPDEVTTPDPTTNASLMNNLQSQNDDWMKNTKI 184
Query 192 HLILRSFKEFLQSSLRALRQ 211
LILRS + FLQ SLRA+R
Sbjct 185 ILILRSLENFLQFSLRAIRI 204
>sp|P41683|IL6_FELCA Interleukin-6 OS=Felis catus OX=9685 GN=IL6
PE=2 SV=1
Length=208
Score = 321 bits (822), Expect = 8e-112, Method: Composition-based stats.
Identities = 123/212 (58%), Positives = 157/212 (74%), Gaps = 4/212 (2%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
M STSAF P+AFSLGLLLV+ AFP P P G D A +R PLTS++++++ I+YI
Sbjct 1 MTFLSTSAFSPLAFSLGLLLVVATAFPTPGPLGGD----ATSNRLPLTSADKMEELIKYI 56
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L ISAL+KE C+ N CE SKEALAENNLNLPK+AEKDGCFQSGFN+ETCL +I TGL
Sbjct 57 LGKISALKKEMCDNYNKCEDSKEALAENNLNLPKLAEKDGCFQSGFNQETCLTRITTGLQ 116
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EF++YL++LQ+++E EE A++V ST VL+Q L++K KN D +T P PT L KLQ
Sbjct 117 EFQIYLKFLQDKYEGDEENAKSVYTSTNVLLQMLKRKGKNQDEVTIPVPTVEVGLQAKLQ 176
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+Q +WL+ T HL LR ++FLQ SLRA+R M
Sbjct 177 SQEEWLRHTTIHLTLRRLEDFLQFSLRAVRIM 208
>sp|P79341|IL6_MACFA Interleukin-6 OS=Macaca fascicularis OX=9541
GN=IL6 PE=2 SV=1
Length=212
Score = 318 bits (815), Expect = 1e-110, Method: Composition-based stats.
Identities = 205/212 (97%), Positives = 208/212 (98%), Gaps = 0/212 (0%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS STSAFGPVAFSLGLLLVLPAAFPAPV PGEDSKDVAAPH QPLTSSERIDK IRYI
Sbjct 1 MNSVSTSAFGPVAFSLGLLLVLPAAFPAPVLPGEDSKDVAAPHSQPLTSSERIDKHIRYI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
LDGISALRKETCN+SNMCESSKEALAENNLNLPKMAEKDGCFQSGFNE+TCLVKIITGLL
Sbjct 61 LDGISALRKETCNRSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEDTCLVKIITGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTP+PTTNASLLTKLQ
Sbjct 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPEPTTNASLLTKLQ 180
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
Sbjct 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
>sp|Q5I6E3|IL6_MACTH Interleukin-6 OS=Macaca thibetana OX=54602
GN=IL6 PE=2 SV=1
Length=212
Score = 318 bits (814), Expect = 2e-110, Method: Composition-based stats.
Identities = 204/212 (96%), Positives = 207/212 (98%), Gaps = 0/212 (0%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS STSAFGPVAFSLGLLLVLPAAFPAPV PGEDSKDVAAPH QPLTSSERIDK IRYI
Sbjct 1 MNSVSTSAFGPVAFSLGLLLVLPAAFPAPVLPGEDSKDVAAPHSQPLTSSERIDKHIRYI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
LDGISALRKETCN+SNMCESSKEALAENNLNLPKMAEKDGCFQSGFNE+TCLVKIITGLL
Sbjct 61 LDGISALRKETCNRSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEDTCLVKIITGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EFEVYLEYLQNRFESSEEQARAVQMSTK LIQFLQKKAKNLDAITTP+PTTNASLLTKLQ
Sbjct 121 EFEVYLEYLQNRFESSEEQARAVQMSTKALIQFLQKKAKNLDAITTPEPTTNASLLTKLQ 180
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
Sbjct 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
>sp|P41323|IL6_CANLF Interleukin-6 OS=Canis lupus familiaris OX=9615
GN=IL6 PE=2 SV=1
Length=207
Score = 317 bits (812), Expect = 3e-110, Method: Composition-based stats.
Identities = 125/212 (59%), Positives = 159/212 (75%), Gaps = 5/212 (2%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS STS AFSLGLLLV+ AFP P P DSKD A + PLTS+ ++++ I+YI
Sbjct 1 MNSLSTS-----AFSLGLLLVMATAFPTPGPLAGDSKDDATSNSLPLTSANKVEELIKYI 55
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L ISALRKE C+K N CE SKEALAENNL+LPK+ KDGCFQSGFN+ETCL +I TGL+
Sbjct 56 LGKISALRKEMCDKFNKCEDSKEALAENNLHLPKLEGKDGCFQSGFNQETCLTRITTGLV 115
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EF+++L LQN +E +E ++V MSTK+L+Q L+ K KN D +TTPDPTT+ASL LQ
Sbjct 116 EFQLHLNILQNNYEGDKENVKSVHMSTKILVQMLKSKVKNQDEVTTPDPTTDASLQAILQ 175
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+Q++ ++ T HLILRS ++FLQ SLRA+R M
Sbjct 176 SQDECVKHTTIHLILRSLEDFLQFSLRAVRIM 207
>sp|Q28819|IL6_PHOVI Interleukin-6 (Fragment) OS=Phoca vitulina
OX=9720 GN=IL6 PE=2 SV=1
Length=209
Score = 317 bits (811), Expect = 5e-110, Method: Composition-based stats.
Identities = 127/208 (61%), Positives = 163/208 (78%), Gaps = 0/208 (0%)
Query 5 STSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGI 64
TSAF PVAFSLGLLLV+ AFP P P G +S+ A +R PLTS +++++ I+YIL I
Sbjct 2 FTSAFSPVAFSLGLLLVMATAFPTPGPVGGESQADATSNRPPLTSPDKMEEFIKYILGKI 61
Query 65 SALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEV 124
SALRKE C+K N CE SKEALAENNL LPK+AEKDGCFQSGFN+ETCL +I TGLLEF++
Sbjct 62 SALRKEMCDKYNKCEDSKEALAENNLRLPKLAEKDGCFQSGFNQETCLTRITTGLLEFQI 121
Query 125 YLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQ 184
+L+Y+Q +E ++E A +V +STK+L+Q L KK K+ D +TTPDPTT+ SL L+AQ++
Sbjct 122 HLKYIQANYEGNKEDANSVYISTKLLVQMLMKKVKSQDEVTTPDPTTDTSLQAILKAQDK 181
Query 185 WLQDMTTHLILRSFKEFLQSSLRALRQM 212
WL+ T HLILRS ++FLQ SLRA+R M
Sbjct 182 WLKHTTIHLILRSLEDFLQFSLRAVRIM 209
>sp|Q8MKH0|IL6_SAISC Interleukin-6 OS=Saimiri sciureus OX=9521
GN=IL6 PE=2 SV=1
Length=212
Score = 317 bits (811), Expect = 5e-110, Method: Composition-based stats.
Identities = 186/212 (88%), Positives = 195/212 (92%), Gaps = 0/212 (0%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
M SFSTSAF PVAFSLGLLLV+PAAFPAPV GEDSK+VAAP+RQ LTS+ERIDK I YI
Sbjct 1 MTSFSTSAFRPVAFSLGLLLVMPAAFPAPVTLGEDSKEVAAPNRQLLTSTERIDKHIWYI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
LDGISALRKE CNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCL+KI TGLL
Sbjct 61 LDGISALRKEICNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLLKITTGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EFEVYLEYLQNRFESS+EQA AVQMSTK LIQ LQ+KAKNL AI TPDP TNASLLTKLQ
Sbjct 121 EFEVYLEYLQNRFESSKEQAGAVQMSTKGLIQSLQRKAKNLSAIATPDPATNASLLTKLQ 180
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
AQ+QWLQ +TTHLILRSFKEFLQ SLRALRQM
Sbjct 181 AQDQWLQGVTTHLILRSFKEFLQCSLRALRQM 212
>sp|P51494|IL6_MACMU Interleukin-6 OS=Macaca mulatta OX=9544 GN=IL6
PE=2 SV=1
Length=212
Score = 316 bits (810), Expect = 7e-110, Method: Composition-based stats.
Identities = 204/212 (96%), Positives = 209/212 (99%), Gaps = 0/212 (0%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNSFSTSAFGPVAFSLGLLLVLPAAFPAPV PGEDSK+VAAPH QPLTSSERIDK IRYI
Sbjct 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVLPGEDSKNVAAPHSQPLTSSERIDKHIRYI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
LDGISALRKETCN+SNMCESSKEALAENNLNLPKMAEKDGCFQSGFNE+TCLVKIITGLL
Sbjct 61 LDGISALRKETCNRSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEDTCLVKIITGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTP+PTTNASLLTKLQ
Sbjct 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPEPTTNASLLTKLQ 180
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
AQNQWLQDMTTHLILRSFKEFLQS+LRALRQM
Sbjct 181 AQNQWLQDMTTHLILRSFKEFLQSNLRALRQM 212
>sp|P46650|IL6_CERAT Interleukin-6 OS=Cercocebus atys OX=9531
GN=IL6 PE=2 SV=1
Length=212
Score = 316 bits (809), Expect = 1e-109, Method: Composition-based stats.
Identities = 203/212 (96%), Positives = 208/212 (98%), Gaps = 0/212 (0%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNSFSTSAFGPVAFSLGLLLVLPAAFPAPV PGEDSKDVAAPH QPLTSSERIDK IRYI
Sbjct 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVLPGEDSKDVAAPHSQPLTSSERIDKHIRYI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
LDGISALRKETCN+SNMC+S+KEALAENNLNLPKMAEKDGCFQSGFNE+TCLVKIITGLL
Sbjct 61 LDGISALRKETCNRSNMCDSTKEALAENNLNLPKMAEKDGCFQSGFNEDTCLVKIITGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQ LQKKAKNLDAITTP+PTTNASLLTKLQ
Sbjct 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQLLQKKAKNLDAITTPEPTTNASLLTKLQ 180
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
Sbjct 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
>sp|Q95181|IL6_HORSE Interleukin-6 OS=Equus caballus OX=9796 GN=IL6
PE=2 SV=2
Length=208
Score = 310 bits (795), Expect = 1e-107, Method: Composition-based stats.
Identities = 129/212 (61%), Positives = 161/212 (76%), Gaps = 4/212 (2%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS STS PVAFSLGLLLV+ AFP P+P GED + LT++++ + I+YI
Sbjct 1 MNSLSTSTVTPVAFSLGLLLVMATAFPTPLPLGED---ETTSNGPLLTTADKTKQHIKYI 57
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L ISAL+ E CN + CE+SKE LAENNLNLPKMAEKDGCFQSGFN+ETCL+KI TGL
Sbjct 58 LGKISALKNEMCNNFSKCENSKEVLAENNLNLPKMAEKDGCFQSGFNQETCLMKITTGLS 117
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EF++YLEYLQN F+ +E + +Q+STKVL+Q L +K KN +TTPDPT +SLL KL
Sbjct 118 EFQIYLEYLQNEFKGEKENIKTMQISTKVLVQILMQKMKNP-EVTTPDPTAKSSLLAKLH 176
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+QN+WL++ TTHLILRS ++FLQ SLRA+R M
Sbjct 177 SQNEWLKNTTTHLILRSLEDFLQFSLRAVRIM 208
>sp|P05231|IL6_HUMAN Interleukin-6 OS=Homo sapiens OX=9606 GN=IL6
PE=1 SV=1
Length=212
Score = 302 bits (774), Expect = 2e-104, Method: Composition-based stats.
Identities = 212/212 (100%), Positives = 212/212 (100%), Gaps = 0/212 (0%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI
Sbjct 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL
Sbjct 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ
Sbjct 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
Sbjct 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
>sp|Q25BC2|IL6_VULVU Interleukin-6 OS=Vulpes vulpes OX=9627 GN=IL6
PE=2 SV=1
Length=207
Score = 300 bits (768), Expect = 2e-103, Method: Composition-based stats.
Identities = 127/212 (60%), Positives = 159/212 (75%), Gaps = 5/212 (2%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS STS AFSLGLLLV+ AFP P P DSKD A PLTS+ ++++ I+YI
Sbjct 1 MNSLSTS-----AFSLGLLLVMATAFPTPGPLAGDSKDDATSISLPLTSANKVEELIKYI 55
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L ISALRKE C+K N CE SKEALAENNL+LP + KDGCFQSGFN+ETCL +I TGL+
Sbjct 56 LGKISALRKEMCDKFNKCEDSKEALAENNLHLPILEGKDGCFQSGFNQETCLTRITTGLM 115
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
EF+++L LQN +E +E A++V MSTK+L+Q L+ K KN D +TTPDPTT+A+L LQ
Sbjct 116 EFQLHLNILQNNYEGDKENAQSVHMSTKILVQMLKSKVKNQDEVTTPDPTTDATLQAILQ 175
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+QN+WL+ T HLILRS ++FLQ SLRA+R M
Sbjct 176 SQNEWLKHTTIHLILRSLEDFLQFSLRAVRIM 207
>sp|P26892|IL6_BOVIN Interleukin-6 OS=Bos taurus OX=9913 GN=IL6
PE=2 SV=1
Length=208
Score = 296 bits (759), Expect = 3e-102, Method: Composition-based stats.
Identities = 109/210 (52%), Positives = 147/210 (70%), Gaps = 4/210 (2%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS TSAF P A SLGLLLV+ +AFP P P GED K+ P R LT+ E+ + I+ +
Sbjct 1 MNSRFTSAFTPFAVSLGLLLVMTSAFPTPGPLGEDFKNDTTPGRLLLTTPEKTEALIKRM 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
+D ISA+RKE C K++ CESSKE LAEN LNLPKM EKDGCFQSGFN+ CL++ GLL
Sbjct 61 VDKISAMRKEICEKNDECESSKETLAENKLNLPKMEEKDGCFQSGFNQAICLIRTTAGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
E+++YL+YLQN +E ++E R ++ + + LIQ L++K +L P TN LL K+Q
Sbjct 121 EYQIYLDYLQNEYEGNQENVRDLRKNIRTLIQILKQKIADL----ITTPATNTDLLEKMQ 176
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALR 210
+ N+W+++ LILR+ + FLQ SLRA+R
Sbjct 177 SSNEWVKNAKIILILRNLENFLQFSLRAIR 206
>sp|Q2MH06|IL6_BUBCA Interleukin-6 OS=Bubalus carabanensis OX=346063
GN=IL6 PE=2 SV=1
Length=208
Score = 296 bits (758), Expect = 5e-102, Method: Composition-based stats.
Identities = 108/210 (51%), Positives = 146/210 (70%), Gaps = 4/210 (2%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS TSAF P A SLGLLLV+ +AFP P P GED K+ P R LT+ E+ + I+ +
Sbjct 1 MNSRFTSAFTPFAVSLGLLLVMTSAFPTPGPLGEDFKNDTTPGRLLLTTPEKTEALIKRM 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
+D ISA+RKE C K++ CESSK+ LAEN LNLPKM EKDGCFQSGFN+ CL++ GLL
Sbjct 61 VDKISAMRKEICEKNDECESSKDTLAENKLNLPKMEEKDGCFQSGFNQAICLIRTTAGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
E+++YL+YLQN +E + E R ++ + + LIQ L++K +L P TN LL K+Q
Sbjct 121 EYQIYLDYLQNEYEGNRENVRDLRKNIRTLIQILKQKIADL----ITTPATNTDLLEKMQ 176
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALR 210
+ N+W+++ LILR+ + FLQ SLRA+R
Sbjct 177 SSNEWVKNAKIILILRNLENFLQFSLRAIR 206
>sp|Q6V919|IL6_BUBBU Interleukin-6 OS=Bubalus bubalis OX=89462
GN=IL6 PE=2 SV=1
Length=208
Score = 296 bits (758), Expect = 5e-102, Method: Composition-based stats.
Identities = 108/210 (51%), Positives = 146/210 (70%), Gaps = 4/210 (2%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS TSAF P A SLGLLLV+ +AFP P P GED K+ P R LT+ E+ + I+ +
Sbjct 1 MNSRFTSAFTPFAVSLGLLLVMTSAFPTPGPLGEDFKNDTTPGRLLLTTPEKTEALIKRM 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
+D ISA+RKE C K++ CESSK+ LAEN LNLPKM EKDGCFQSGFN+ CL++ GLL
Sbjct 61 VDKISAMRKEICEKNDECESSKDTLAENKLNLPKMEEKDGCFQSGFNQAICLIRTTAGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
E+++YL+YLQN +E + E R ++ + + LIQ L++K +L P TN LL K+Q
Sbjct 121 EYQIYLDYLQNEYEGNRENVRDLRKNIRTLIQILKQKIADL----ITTPATNTDLLEKMQ 176
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALR 210
+ N+W+++ LILR+ + FLQ SLRA+R
Sbjct 177 SSNEWVKNAKIILILRNLENFLQFSLRAIR 206
>sp|Q28319|IL6_CAPHI Interleukin-6 OS=Capra hircus OX=9925 GN=IL6
PE=2 SV=1
Length=208
Score = 291 bits (746), Expect = 3e-100, Method: Composition-based stats.
Identities = 109/210 (52%), Positives = 146/210 (70%), Gaps = 4/210 (2%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS TSAF P+A SLGLLLV+ +AFP P P GED K+ P R LT+ E+ + I++I
Sbjct 1 MNSLFTSAFSPLAVSLGLLLVMTSAFPTPGPLGEDFKNDTTPSRLLLTTPEKTEALIKHI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
+D ISA+RKE C K++ CE+SKE LAEN L LPKM EKDGCFQSGFN+ CL+K GLL
Sbjct 61 VDKISAIRKEICEKNDECENSKETLAENKLKLPKMEEKDGCFQSGFNQAICLIKTTAGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
E+++YL++LQN FE ++E +Q S + LIQ L++K L P TN +L K+Q
Sbjct 121 EYQIYLDFLQNEFEGNQETVMELQSSIRTLIQILKEKIAGL----ITTPATNTDMLEKMQ 176
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALR 210
+ N+W+++ +ILRS + FLQ SLRA+R
Sbjct 177 SSNEWVKNAKVIIILRSLENFLQFSLRAIR 206
>sp|P29455|IL6_SHEEP Interleukin-6 OS=Ovis aries OX=9940 GN=IL6
PE=2 SV=2
Length=208
Score = 290 bits (743), Expect = 9e-100, Method: Composition-based stats.
Identities = 108/210 (51%), Positives = 146/210 (70%), Gaps = 4/210 (2%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
MNS TSAF P+A SLGLLLV+ +AFP P P GED K+ P R LT+ E+ + I++I
Sbjct 1 MNSLFTSAFSPLAVSLGLLLVMTSAFPTPGPLGEDFKNDTTPSRLLLTTPEKTEALIKHI 60
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
+D ISA+RKE C K++ CE+SKE LAEN L LPKM EKDGCFQSGFN+ CL+K GLL
Sbjct 61 VDKISAIRKEICEKNDECENSKETLAENKLKLPKMEEKDGCFQSGFNQAICLIKTTAGLL 120
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
E+++YL++LQN FE ++E +Q S + LIQ L++K L P T+ +L K+Q
Sbjct 121 EYQIYLDFLQNEFEGNQETVMELQSSIRTLIQILKEKIAGL----ITTPATHTDMLEKMQ 176
Query 181 AQNQWLQDMTTHLILRSFKEFLQSSLRALR 210
+ N+W+++ +ILRS + FLQ SLRA+R
Sbjct 177 SSNEWVKNAKVIIILRSLENFLQFSLRAIR 206
>sp|P08505|IL6_MOUSE Interleukin-6 OS=Mus musculus OX=10090 GN=Il6
PE=1 SV=1
Length=211
Score = 269 bits (688), Expect = 3e-91, Method: Composition-based stats.
Identities = 87/212 (41%), Positives = 134/212 (63%), Gaps = 3/212 (1%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
M S F PVAF LGL+LV AFP D + P+R P+ ++ ++ I ++
Sbjct 1 MKFLSARDFHPVAF-LGLMLVTTTAFPTSQVRRGDFTEDTTPNR-PVYTTSQVGGLITHV 58
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L I +RKE CN ++ C ++ +ALAENNL LP++ DGC+Q+G+N+E CL+KI +GLL
Sbjct 59 LWEIVEMRKELCNGNSDCMNNDDALAENNLKLPEIQRNDGCYQTGYNQEICLLKISSGLL 118
Query 121 EFEVYLEYLQNRF-ESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKL 179
E+ YLEY++N ++ +++AR +Q T+ LI ++ K+L I P P +NA L KL
Sbjct 119 EYHSYLEYMKNNLKDNKKDKARVLQRDTETLIHIFNQEVKDLHKIVLPTPISNALLTDKL 178
Query 180 QAQNQWLQDMTTHLILRSFKEFLQSSLRALRQ 211
++Q +WL+ T IL+S +EFL+ +LR+ RQ
Sbjct 179 ESQKEWLRTKTIQFILKSLEEFLKVTLRSTRQ 210
>sp|P20607|IL6_RAT Interleukin-6 OS=Rattus norvegicus OX=10116
GN=Il6 PE=2 SV=1
Length=211
Score = 259 bits (663), Expect = 2e-87, Method: Composition-based stats.
Identities = 85/212 (40%), Positives = 137/212 (65%), Gaps = 3/212 (1%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
M S F PVAF LGL+L+ AFP D + +R P+ ++ ++ I Y+
Sbjct 1 MKFLSARDFQPVAF-LGLMLLTATAFPTSQVRRGDFTEDTTHNR-PVYTTSQVGGLITYV 58
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
L I +RKE CN ++ C +S +AL+ENNL LP++ DGCFQ+G+N+E CL+KI +GLL
Sbjct 59 LREILEMRKELCNGNSDCMNSDDALSENNLKLPEIQRNDGCFQTGYNQEICLLKICSGLL 118
Query 121 EFEVYLEYLQNRF-ESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKL 179
EF YLE+++N ++ +++AR +Q +T+ L+ +++ K+ I P PT+NA L+ KL
Sbjct 119 EFRFYLEFVKNNLQDNKKDKARVIQSNTETLVHIFKQEIKDSYKIVLPTPTSNALLMEKL 178
Query 180 QAQNQWLQDMTTHLILRSFKEFLQSSLRALRQ 211
++Q +WL+ T LIL++ +EFL+ ++R+ RQ
Sbjct 179 ESQKEWLRTKTIQLILKALEEFLKVTMRSTRQ 210
>sp|O35736|IL6_MARMO Interleukin-6 OS=Marmota monax OX=9995 GN=IL6
PE=2 SV=1
Length=207
Score = 257 bits (656), Expect = 1e-86, Method: Composition-based stats.
Identities = 95/213 (45%), Positives = 140/213 (66%), Gaps = 9/213 (4%)
Query 1 MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI 60
M FS + SLGLLLV+ AFPA ED ++ ++ SS + +QI Y+
Sbjct 1 MKFFSIA-------SLGLLLVVATAFPASELQREDGENSVTRNKPTRASSGKTRRQISYL 53
Query 61 LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL 120
+ + +RKE C C S A++ENNLNLPKM EKDGCFQ+G+N + CLV+I +GLL
Sbjct 54 IKEVFEMRKELCKNDETCIKSHVAVSENNLNLPKMTEKDGCFQTGYNRDDCLVRITSGLL 113
Query 121 EFEVYLEYLQNRFE--SSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTK 178
EF+VYL Y++N+F+ ++ ++A VQ S+K LI+ L+++ K+ + I P PT N +LL K
Sbjct 114 EFQVYLRYIRNKFQEGNNRDRAEHVQSSSKALIEILKQEVKDPNKIVFPSPTANINLLAK 173
Query 179 LQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQ 211
L++QN W + MT LIL +F++FLQ +LRA+R+
Sbjct 174 LESQNDWQKVMTMQLILSNFEDFLQFTLRAVRK 206
>sp|Q9MZR1|IL6_RABIT Interleukin-6 OS=Oryctolagus cuniculus OX=9986
GN=IL6 PE=2 SV=1
Length=241
Score = 253 bits (646), Expect = 2e-84, Method: Composition-based stats.
Identities = 102/216 (47%), Positives = 132/216 (61%), Gaps = 6/216 (3%)
Query 1 MNSFSTSAF--GPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIR 58
MNSF TSA GP+ SL LLLV+ AFP P EDS A+P + LT R + IR
Sbjct 1 MNSF-TSALRPGPLGCSLALLLVVATAFPTSAPVREDSNTKASPDK-TLTPPGRTIESIR 58
Query 59 YILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITG 118
IL+ I LRKE C+ C + KEALAE NL+LP++ E+DGCF N ETCL++I +G
Sbjct 59 SILETIKELRKEMCDHDVNCMNRKEALAEVNLHLPRLIEEDGCFPPAVNNETCLLRITSG 118
Query 119 LLEFEVYLEYLQNRFESSEEQARA--VQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLL 176
L+EF +YLE+LQ +F S EE R V + + LI+ L+ K KNL+ T P SL+
Sbjct 119 LMEFRMYLEHLQAKFRSDEENTRVSMVLKNIQHLIKTLRPKVKNLNEEATLKPAVAVSLM 178
Query 177 TKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
LQ +NQWL+ T H ILR FL+ +LRA+ M
Sbjct 179 ENLQQKNQWLKTTTIHFILRGLTNFLEFTLRAVDLM 214
>sp|Q90YI0|IL6_CHICK Interleukin-6 OS=Gallus gallus OX=9031 GN=IL6
PE=2 SV=1
Length=241
Score = 211 bits (537), Expect = 6e-68, Method: Composition-based stats.
Identities = 68/180 (38%), Positives = 105/180 (58%), Gaps = 3/180 (2%)
Query 33 GEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNL 92
GE + A R+ L E + + +R D L+ E C K +CE+S E L NNLNL
Sbjct 57 GEVGLEEEAGARRALLDCEPLARVLR---DRAVQLQDEMCKKFTVCENSMEMLVRNNLNL 113
Query 93 PKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQ 152
PK+ E+DGC +GF+EE CL K+ +GL F+ YLE++Q F+S ++ ++ STK L
Sbjct 114 PKVTEEDGCLLAGFDEEKCLTKLSSGLFAFQTYLEFIQETFDSEKQNVESLCYSTKHLAA 173
Query 153 FLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+++ N D + PD SLL L++ W++ +T HLILR F F++ ++RA+R +
Sbjct 174 TIRQMVINPDEVVIPDSAAQKSLLANLKSDKDWIEKITMHLILRDFTSFMEKTVRAVRYL 233
>sp|P41693|IL6_NEOVI Interleukin-6 (Fragment) OS=Neovison vison
OX=452646 GN=IL6 PE=2 SV=1
Length=125
Score = 182 bits (461), Expect = 5e-58, Method: Composition-based stats.
Identities = 67/127 (53%), Positives = 96/127 (76%), Gaps = 2/127 (2%)
Query 86 AENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQM 145
AENNL LPK+AEKD CFQS FN+ETC+ +I TGL EF+++L+YL+ +E ++ A +V +
Sbjct 1 AENNLKLPKLAEKDKCFQSQFNQETCMTRITTGLQEFQIHLKYLEANYEGNKNNAHSVYI 60
Query 146 STKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSS 205
STK L+Q L+ N +TTP+PTT++SL ++Q++WL+ +T HLILRS ++FLQ S
Sbjct 61 STKHLLQKLRPM--NQVEVTTPNPTTDSSLQALFKSQDKWLKHVTIHLILRSLEDFLQFS 118
Query 206 LRALRQM 212
LRA+R M
Sbjct 119 LRAIRIM 125
>sp|Q2HRC7|VIL6_HHV8P Viral interleukin-6 homolog OS=Human herpesvirus
8 type P (isolate GK18) OX=868565 GN=K2 PE=1 SV=1
Length=204
Score = 184 bits (467), Expect = 8e-58, Method: Composition-based stats.
Identities = 42/167 (25%), Positives = 80/167 (48%), Gaps = 0/167 (0%)
Query 46 PLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSG 105
P + + +++ ++L I ++ C ++ +C+ E A +L LP + + D C G
Sbjct 28 PEFEKDLLIQRLNWMLWVIDECFRDLCYRTGICKGILEPAAIFHLKLPAINDTDHCGLIG 87
Query 106 FNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAIT 165
FNE +CL K+ G EFEV ++L F S +++ TK L +Q++ L
Sbjct 88 FNETSCLKKLADGFFEFEVLFKFLTTEFGKSVINVDVMELLTKTLGWDIQEELNKLTKTH 147
Query 166 TPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
P + LL +LQ W++ + +L + ++F ++R L +
Sbjct 148 YSPPKFDRGLLGRLQGLKYWVRHFASFYVLSAMEKFAGQAVRVLNSI 194
>sp|P13854|MGF_CHICK Myelomonocytic growth factor OS=Gallus gallus
OX=9031 PE=2 SV=1
Length=201
Score = 155 bits (391), Expect = 2e-46, Method: Composition-based stats.
Identities = 37/161 (23%), Positives = 69/161 (43%), Gaps = 3/161 (2%)
Query 52 RIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETC 111
+ + R I ++AL++ C+ +C + L + + +L + A D C + GF E C
Sbjct 41 KNLEFTRKIRGDVAALQRAVCDTFQLCTEEELQLVQPDPHLVQ-APLDQCHKRGFQAEVC 99
Query 112 LVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTT 171
+I GL + L + + +Q+ L +Q++ ++L T P
Sbjct 100 FTQIRAGLHAYHDSLGAVLRLLPNHTTLVETLQLDAANLSSNIQQQMEDLGLDTVTLPAE 159
Query 172 NASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
S Q Q + IL +F+ FL+++ RALR +
Sbjct 160 QRSPPPTFSGPFQ--QQVGGFFILANFQRFLETAYRALRHL 198
>sp|A0S0B0|IL6_PAROL Interleukin-6 OS=Paralichthys olivaceus OX=8255
GN=il6 PE=2 SV=1
Length=230
Score = 145 bits (366), Expect = 2e-42, Method: Composition-based stats.
Identities = 40/185 (22%), Positives = 76/185 (41%), Gaps = 10/185 (5%)
Query 27 PAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALA 86
P P G D L S+ + I + + +KE ++ +
Sbjct 31 PTDSPAG-DFSGEEQEVTPDLLSASPVWDLI---IGVTAHHQKEFEDEFQ---QEVKYRF 83
Query 87 ENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMS 146
N+ L + C + F++E CL ++ GL + V ++++ + SS A +
Sbjct 84 LNHYKLSSLPAD--CPSANFSKEACLQRLAEGLHTYMVLFKHVEKEYPSSSILLHA-RYH 140
Query 147 TKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSL 206
+ LI +++K +N +T P LL + + + + MT H ILR FL++
Sbjct 141 SGALIGLIKEKMRNPGQVTVPTSRQEQQLLQDMDNPSTFHRKMTAHNILRQLHNFLRNGK 200
Query 207 RALRQ 211
A+R+
Sbjct 201 VAIRK 205
>sp|Q6L6X6|IL6_TAKRU Interleukin-6 OS=Takifugu rubripes OX=31033
GN=il6 PE=2 SV=1
Length=227
Score = 132 bits (333), Expect = 2e-37, Method: Composition-based stats.
Identities = 41/185 (22%), Positives = 77/185 (42%), Gaps = 10/185 (5%)
Query 27 PAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALA 86
P P GE S + A + + + +L + E + E + L
Sbjct 28 PTESPAGETSGEEAETGSP----DDALAVALESVLGATKLHKNEFLVEFQG-EVKYDFL- 81
Query 87 ENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMS 146
+ +P + K C S F ++ CL +++ GLL + V L+ ++ F SS + V+
Sbjct 82 -DRYKIPSLPAK--CPYSNFGKDACLRRLLEGLLIYSVLLKRVEEEFPSSSILSE-VRFY 137
Query 147 TKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSL 206
+ +LI+ L+ K ++ D + + LL + + + MT H IL + FL
Sbjct 138 SNILIKELENKVRDRDQVMRLTSSQEEQLLKDTDYPDTFHRKMTAHGILYNLHYFLVDCR 197
Query 207 RALRQ 211
R + +
Sbjct 198 RVINK 202
>sp|Q0GGL7|IL6_ONCMY Interleukin-6 OS=Oncorhynchus mykiss OX=8022
GN=il6 PE=2 SV=1
Length=219
Score = 125 bits (314), Expect = 1e-34, Method: Composition-based stats.
Identities = 44/205 (21%), Positives = 91/205 (44%), Gaps = 16/205 (8%)
Query 10 GPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALR- 68
PV +L L + + + + G D + A P + +K I+ ++ ++ LR
Sbjct 21 NPVPSALAEL--MTSGWTSGEELGTDGETGAPP---------KWEKMIKMLVHEVTTLRN 69
Query 69 KETCNKSNMCESSKEALAENN-LNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLE 127
++ + + +++ + P K C S N+E CL +I GL +++ L+
Sbjct 70 QQFVEEFQKPVEEISSFSQHQVPSTPPHLSKTLC--SASNKEACLQEISRGLQVYQLLLQ 127
Query 128 YLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQ 187
+++ + S +V T VLI ++ + K + + + +L ++ +W +
Sbjct 128 HVKAEYPQST-LLPSVTHQTTVLIGLVKDQMKVAEVVEDLSASERKRVLGEVSTGTEWER 186
Query 188 DMTTHLILRSFKEFLQSSLRALRQM 212
+ H ILR + FL + RALR+M
Sbjct 187 KTSVHAILRELRNFLVDTKRALRRM 211
>sp|B6CKP4|IL6_SPAAU Interleukin-6 OS=Sparus aurata OX=8175 GN=il6
PE=2 SV=1
Length=225
Score = 99.8 bits (247), Expect = 1e-24, Method: Composition-based stats.
Identities = 39/187 (21%), Positives = 84/187 (45%), Gaps = 13/187 (7%)
Query 25 AFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEA 84
AF P G+ S + R ++ + ++ +L+ I R+E + ++ +
Sbjct 30 AF-TDNPAGDTSGEEWETERP----ADPLIALLKVVLEVIKTHRQEFEAEFHI---RYDV 81
Query 85 LAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQ 144
LA+ N+P + C + F+ E L +++ GL + L+Y++ S+ +R +
Sbjct 82 LAQ--YNIPSLPAD--CPSTNFSMEALLHRLLQGLPVYTALLKYVEKEEPKSQIPSR-FR 136
Query 145 MSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQS 204
++++L Q + K ++ +T + LL L + + + + MT H IL + FL
Sbjct 137 QNSELLKQRITGKMRHAVQVTPLTSSQEQQLLRDLDSSDTFHRKMTAHSILYQLRSFLVD 196
Query 205 SLRALRQ 211
A+ +
Sbjct 197 CKNAINK 203
>sp|P35834|CSF3_CANLF Granulocyte colony-stimulating factor OS=Canis
lupus familiaris OX=9615 GN=CSF3 PE=1 SV=1
Length=175
Score = 73.2 bits (178), Expect = 4e-15, Method: Composition-based stats.
Identities = 29/160 (18%), Positives = 62/160 (39%), Gaps = 5/160 (3%)
Query 52 RIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETC 111
+ +Q+R + +AL++ C +C + L + L +P+ C C
Sbjct 17 KCLEQMRKVQADGTALQETLCATHQLCHPEELVLLGHALGIPQ-PPLSSCSSQALQLMGC 75
Query 112 LVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTT 171
L ++ +GL ++ L+ L +Q+ T + ++ ++L PT
Sbjct 76 LRQLHSGLFLYQGLLQALAGISPELAPTLDTLQLDTTDFAINIWQQMEDLGMAPAVPPTQ 135
Query 172 NASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQ 211
+ + Q + L+ + + FL+ + RALR
Sbjct 136 GT--MPAFTSAFQ--RRAGGVLVASNLQSFLELAYRALRH 171
>sp|P09919|CSF3_HUMAN Granulocyte colony-stimulating factor OS=Homo
sapiens OX=9606 GN=CSF3 PE=1 SV=1
Length=207
Score = 73.6 bits (179), Expect = 6e-15, Method: Composition-based stats.
Identities = 31/164 (19%), Positives = 63/164 (38%), Gaps = 8/164 (5%)
Query 52 RIDKQIRYILDGISALRKET---CNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNE 108
+ +Q+R I +AL+++ C +C + L ++L +P A C
Sbjct 46 KCLEQVRKIQGDGAALQEKLVSECATYKLCHPEELVLLGHSLGIP-WAPLSSCPSQALQL 104
Query 109 ETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPD 168
CL ++ +GL ++ L+ L+ +Q+ + ++ + L
Sbjct 105 AGCLSQLHSGLFLYQGLLQALEGISPELGPTLDTLQLDVADFATTIWQQMEELGMAPALQ 164
Query 169 PTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
PT A + + Q + L+ + FL+ S R LR +
Sbjct 165 PTQGA--MPAFASAFQ--RRAGGVLVASHLQSFLEVSYRVLRHL 204
>sp|P09920|CSF3_MOUSE Granulocyte colony-stimulating factor OS=Mus
musculus OX=10090 GN=Csf3 PE=1 SV=1
Length=208
Score = 72.0 bits (175), Expect = 2e-14, Method: Composition-based stats.
Identities = 39/193 (20%), Positives = 76/193 (39%), Gaps = 18/193 (9%)
Query 20 LVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCE 79
LV +A P +P P + + +Q+R I S L ++ C +C
Sbjct 33 LVTVSALPPSLPL-------------PRSFLLKSLEQVRKIQASGSVLLEQLCATYKLCH 79
Query 80 SSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQ 139
+ L ++L +PK A GC + CL ++ +GL ++ L+ L +
Sbjct 80 PEELVLLGHSLGIPK-ASLSGCSSQALQQTQCLSQLHSGLCLYQGLLQALSGISPALAPT 138
Query 140 ARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFK 199
+Q+ + ++ +NL T PT +A + + Q + L + +
Sbjct 139 LDLLQLDVANFATTIWQQMENLGVAPTVQPTQSA--MPAFTSAFQ--RRAGGVLAISYLQ 194
Query 200 EFLQSSLRALRQM 212
FL+++ AL +
Sbjct 195 GFLETARLALHHL 207
>sp|O02708|CSF3_FELCA Granulocyte colony-stimulating factor (Fragment)
OS=Felis catus OX=9685 GN=CSF3 PE=2 SV=1
Length=194
Score = 71.2 bits (173), Expect = 4e-14, Method: Composition-based stats.
Identities = 28/160 (18%), Positives = 62/160 (39%), Gaps = 5/160 (3%)
Query 52 RIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETC 111
+ +Q+R + +AL++ C +C + L + L +P+ A C C
Sbjct 36 KCLEQVRKVQADGTALQERLCAAHKLCHPEELVLLGHALGIPQ-APLSSCSSQALQLTGC 94
Query 112 LVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTT 171
L ++ +GL ++ L+ L +Q+ + ++ +++ PT
Sbjct 95 LRQLHSGLFLYQGLLQALAGISPELAPTLDMLQLDITDFAINIWQQMEDVGMAPAVPPTQ 154
Query 172 NASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQ 211
+ + Q + L+ + + FL+ + RALR
Sbjct 155 GT--MPTFTSAFQ--RRAGGTLVASNLQSFLEVAYRALRH 190
>sp|O02837|CSF3_PIG Granulocyte colony-stimulating factor OS=Sus
scrofa OX=9823 GN=CSF3 PE=2 SV=2
Length=195
Score = 66.2 bits (160), Expect = 2e-12, Method: Composition-based stats.
Identities = 30/161 (19%), Positives = 62/161 (39%), Gaps = 5/161 (3%)
Query 52 RIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETC 111
+ +Q+R I + L++ C +C + L ++L LP+ A C C
Sbjct 37 KCLEQVRKIQADGAELQERLCATHKLCHPQELVLLGHSLGLPQ-ASLSSCSSQALQLTGC 95
Query 112 LVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTT 171
L ++ GL+ ++ L+ L +Q+ L + + ++L PT
Sbjct 96 LNQLHGGLVLYQGLLQALAGISPELAPALDILQLDVTDLATNIWLQMEDLRMAPASLPTQ 155
Query 172 NASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+ + Q + L++ + FL+ + R LR +
Sbjct 156 GT--VPTFTSAFQ--RRAGGVLVVSQLQSFLELAYRVLRYL 192
>sp|P35833|CSF3_BOVIN Granulocyte colony-stimulating factor OS=Bos
taurus OX=9913 GN=CSF3 PE=1 SV=2
Length=195
Score = 65.1 bits (157), Expect = 6e-12, Method: Composition-based stats.
Identities = 32/178 (18%), Positives = 65/178 (37%), Gaps = 9/178 (5%)
Query 39 VAAPHRQPLTSSE----RIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPK 94
A P + + + +Q+R I + L++ C +C + L ++L +P+
Sbjct 20 EATPLGPARSLPQSFLLKCLEQVRKIQADGAELQERLCAAHKLCHPEELMLLRHSLGIPQ 79
Query 95 MAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFL 154
A C +CL ++ GL ++ L+ L +Q+ +
Sbjct 80 -APLSSCSSQSLQLTSCLNQLHGGLFLYQGLLQALAGISPELAPTLDTLQLDVTDFATNI 138
Query 155 QKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+ ++L A PT A + + Q + L+ FL+ + R LR +
Sbjct 139 WLQMEDLGAAPAVQPTQGA--MPTFTSAFQ--RRAGGVLVASQLHRFLELAYRGLRYL 192
>sp|Q28746|CSF3_SHEEP Granulocyte colony-stimulating factor OS=Ovis
aries OX=9940 GN=CSF3 PE=2 SV=1
Length=174
Score = 61.2 bits (147), Expect = 1e-10, Method: Composition-based stats.
Identities = 28/161 (17%), Positives = 59/161 (37%), Gaps = 5/161 (3%)
Query 52 RIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETC 111
+ +Q+R I + L++ C +C + L ++L +P+ A C +C
Sbjct 16 KCLEQVRKIQADGAELQERLCATHKLCHPEELVLLGHSLGIPQ-APLSSCSSQSLQLTSC 74
Query 112 LVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTT 171
L ++ GL ++ L+ L +Q+ + + ++L PT
Sbjct 75 LDQLHGGLFLYQGLLQALAGISPELAPTLDTLQLDVTDFATNIWLQMEDLGVAPAVQPTQ 134
Query 172 NASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM 212
+ + Q + L+ + FL + R LR +
Sbjct 135 GT--MPTFTSAFQ--RRAGGVLVASQLQRFLGLAYRGLRYL 171
>sp|Q9EQ14|IL23A_MOUSE Interleukin-23 subunit alpha OS=Mus musculus
OX=10090 GN=Il23a PE=1 SV=1
Length=196
Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats.
Identities = 28/130 (22%), Positives = 48/130 (37%), Gaps = 9/130 (7%)
Query 81 SKEALAENNLNLPKMAEKDGCFQSGF--NEETCLVKIITGLLEFEVYLEYLQNRFESSEE 138
+E E N+P++ +DGC G N + CL +I GL ++ L+ + F+
Sbjct 58 REEEDEETKNNVPRIQCEDGCDPQGLKDNSQFCLQRIRQGLAFYKHLLD--SDIFKGEPA 115
Query 139 QARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSF 198
M + + D + L + QW + + ILRS
Sbjct 116 LLPDSPMEQLHTSLLGLSQLLQPE-----DHPRETQQMPSLSSSQQWQRPLLRSKILRSL 170
Query 199 KEFLQSSLRA 208
+ FL + R
Sbjct 171 QAFLAIAARV 180
>sp|Q91Z84|IL23A_RAT Interleukin-23 subunit alpha OS=Rattus norvegicus
OX=10116 GN=Il23a PE=2 SV=1
Length=196
Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats.
Identities = 29/131 (22%), Positives = 53/131 (40%), Gaps = 11/131 (8%)
Query 81 SKEALAENNLNLPKMAEKDGCFQSGF--NEETCLVKIITGLLEFEVYLEY-LQNRFESSE 137
+E E ++P++ DGC G N + CL +I GL+ ++ L+ + S
Sbjct 58 REEGEEETKSDVPRIQCGDGCDPQGLKDNSQFCLQRIRQGLVFYKHLLDSDIFTGEPSLL 117
Query 138 EQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRS 197
+ Q+ T +L + ++ T + +L QW + + ILRS
Sbjct 118 PDSPVDQLHTSLLGLSQLLQPEDHHWET--------QQMPRLSPSQQWQRSLLRSKILRS 169
Query 198 FKEFLQSSLRA 208
+ FL + R
Sbjct 170 LQAFLAIAARV 180
>sp|Q64FU1|IL23A_HORSE Interleukin-23 subunit alpha OS=Equus caballus
OX=9796 GN=IL23A PE=3 SV=1
Length=192
Score = 47.4 bits (111), Expect = 2e-05, Method: Composition-based stats.
Identities = 32/134 (24%), Positives = 54/134 (40%), Gaps = 17/134 (13%)
Query 81 SKEALAENNLNLPKMAEKDGCFQSGF--NEETCLVKIITGLLEFEVYLEY-LQNRFESSE 137
+E AE ++P + +DGC G N + CL +I GL+ +E L + S
Sbjct 60 REEGDAETTNDVPHIQCEDGCDPEGLRDNSQPCLQRIHQGLVFYEKLLGSDIFTGEPSLL 119
Query 138 EQARAVQMSTKVLI--QFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQ-WLQDMTTHLI 194
Q+ +L Q LQ + + + P P + +Q W + + I
Sbjct 120 PNGPVDQLHASLLGLRQLLQPEGHHWETEQIPSP-----------SPSQPWQRLLLRPKI 168
Query 195 LRSFKEFLQSSLRA 208
LRS + F+ + R
Sbjct 169 LRSLQAFVAVAARV 182
>sp|Q9NPF7|IL23A_HUMAN Interleukin-23 subunit alpha OS=Homo sapiens
OX=9606 GN=IL23A PE=1 SV=1
Length=189
Score = 38.5 bits (88), Expect = 0.015, Method: Composition-based stats.
Identities = 33/181 (18%), Positives = 62/181 (34%), Gaps = 18/181 (10%)
Query 31 PPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNL 90
P + V T +++ +++ + L ++ E E E
Sbjct 14 PWTAQGRAVPGGSSPAWTQCQQLSQKLCTLAWSAHPLVGHM----DLREEGDE---ETTN 66
Query 91 NLPKMAEKDGCFQSGF--NEETCLVKIITGLLEFEVYLEY-LQNRFESSEEQARAVQMST 147
++P + DGC G N + CL +I GL+ +E L + S + Q+
Sbjct 67 DVPHIQCGDGCDPQGLRDNSQFCLQRIHQGLIFYEKLLGSDIFTGEPSLLPDSPVGQLHA 126
Query 148 KVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLR 207
+L + + T P+ L W + + ILRS + F+ + R
Sbjct 127 SLLGLSQLLQPEGHHWETQQIPS--------LSPSQPWQRLLLRFKILRSLQAFVAVAAR 178
Query 208 A 208
Sbjct 179 V 179
>sp|Q9N2H9|IL23A_PIG Interleukin-23 subunit alpha OS=Sus scrofa
OX=9823 GN=IL23A PE=3 SV=1
Length=193
Score = 38.1 bits (87), Expect = 0.026, Method: Composition-based stats.
Identities = 25/99 (25%), Positives = 39/99 (39%), Gaps = 13/99 (13%)
Query 79 ESSKEALAENNLNLPKMAEKDGCFQSGF--NEETCLVKIITGLLEFEVYLEYLQNRFESS 136
E E +E +P + DGC G N ++CL +I GL+ +E L + F
Sbjct 63 EGDDETTSE----VPHIQCGDGCDPQGLRDNSQSCLQRIHQGLVFYEKLLG--SDIFTGE 116
Query 137 EEQ-----ARAVQMSTKVLIQFLQKKAKNLDAITTPDPT 170
+ S L Q LQ + + + TP P+
Sbjct 117 PSLHPDGSVGQLHASLLGLRQLLQPEGHHWETEQTPSPS 155
>sp|Q6LA37|IL23A_CAVPO Interleukin-23 subunit alpha OS=Cavia porcellus
OX=10141 GN=IL23A PE=2 SV=1
Length=189
Score = 37.4 bits (85), Expect = 0.039, Method: Composition-based stats.
Identities = 27/130 (21%), Positives = 46/130 (35%), Gaps = 10/130 (8%)
Query 81 SKEALAENNLNLPKMAEKDGCFQSGF--NEETCLVKIITGLLEFEVYLEYLQNRFESSEE 138
+EA E +P + DGC G N + CL +I GL+ ++ L + F
Sbjct 58 REEADEETTDYVPHILCGDGCDPQGLKDNSQFCLQRIYQGLVFYQNLLG--SDIFTGEPP 115
Query 139 QARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSF 198
+S + + +P + L W + + ILRSF
Sbjct 116 LFPDGPVSQLHASLLGLSQLLQP-EVHQWEPQ-----IPSLSPNQPWQRLLLRIKILRSF 169
Query 199 KEFLQSSLRA 208
+ F+ + R
Sbjct 170 QAFVAVAARV 179
>sp|Q06194|FA8_MOUSE Coagulation factor VIII OS=Mus musculus OX=10090
GN=F8 PE=2 SV=2
Length=2319
Score = 35.8 bits (81), Expect = 0.33, Method: Composition-based stats.
Identities = 27/131 (21%), Positives = 50/131 (38%), Gaps = 17/131 (13%)
Query 73 NKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNR 132
K+ E KEAL E + LP++ E G F ++ ++ + +EV++ LQN
Sbjct 1212 EKNIQEEIEKEALIEEKVVLPQVHEATG--SKNFLKDILILGTRQNISLYEVHVPVLQN- 1268
Query 133 FESSEEQARAVQMSTKV--------------LIQFLQKKAKNLDAITTPDPTTNASLLTK 178
S VQ+ + L+ ++ KN + + L +
Sbjct 1269 ITSINNSTNTVQIHMEHFFKRRKDKETNSEGLVNKTREMVKNYPSQKNITTQRSKRALGQ 1328
Query 179 LQAQNQWLQDM 189
+ QWL+ +
Sbjct 1329 FRLSTQWLKTI 1339
>sp|Q18237|SMC5_CAEEL Structural maintenance of chromosomes protein
5 OS=Caenorhabditis elegans OX=6239 GN=smc-5 PE=1 SV=2
Length=1076
Score = 35.4 bits (80), Expect = 0.33, Method: Composition-based stats.
Identities = 42/169 (25%), Positives = 72/169 (43%), Gaps = 5/169 (3%)
Query 16 LGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKS 75
LG ++ F AP P + +V+ +R P S+ ++K+I + I R +
Sbjct 525 LGFKYLVSNCFDAPAPLKQFLCNVSGLNRIPFGGSD-VEKKIAEVSQAIEQTRYSVFLTA 583
Query 76 NM-CESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITG--LLEFEVYLEYLQNR 132
N+ C++SK A N L + ++ F + + + K L E + + R
Sbjct 584 NIRCQNSKSRYANNTLQSQSATREANTWRDQFFKVSPVAKRTDNSILEEIQKLKAEIDIR 643
Query 133 FESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQA 181
E E+ A+Q VL Q Q + K+ + T T AS + KL+A
Sbjct 644 SEQLREKRGAIQKERDVLRQE-QMQWKSKKQVHTKWKTELASEMAKLEA 691
>sp|Q99567|NUP88_HUMAN Nuclear pore complex protein Nup88 OS=Homo
sapiens OX=9606 GN=NUP88 PE=1 SV=2
Length=741
Score = 33.9 bits (76), Expect = 0.99, Method: Composition-based stats.
Identities = 29/145 (20%), Positives = 47/145 (32%), Gaps = 37/145 (26%)
Query 21 VLPAAFPAPVPP---GEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNM 77
+L PA P ED + +P R + + +K IR IL A
Sbjct 494 LLSTVHPASPPLLCTREDVEVAESPLRVLAETPDSFEKHIRSILQRSVA----------- 542
Query 78 CESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSE 137
N K +EKD E CL + F ++ +
Sbjct 543 -----------NPAFLKASEKDIAPPP----EECLQLLSRATQVFR-------EQYILKQ 580
Query 138 EQA-RAVQMSTKVLIQFLQKKAKNL 161
+ A +Q K+L +K+ ++L
Sbjct 581 DLAKEEIQRRVKLLCDQKKKQLEDL 605
>sp|Q13464|ROCK1_HUMAN Rho-associated protein kinase 1 OS=Homo
sapiens OX=9606 GN=ROCK1 PE=1 SV=1
Length=1354
Score = 33.5 bits (75), Expect = 1.6, Method: Composition-based stats.
Identities = 27/158 (17%), Positives = 61/158 (39%), Gaps = 18/158 (11%)
Query 35 DSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPK 94
D++ + + S ++ ++ L L+ E C +S N+ L K
Sbjct 413 DNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEM---EQKCRTS-------NIKLDK 462
Query 95 -MAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQF 153
M E D N E+ + +I ++ L++ N ++ EQ + + + +
Sbjct 463 IMKELDEEGNQRRNLESTVSQIEKE----KMLLQHRINEYQRKAEQENEKRRNVENEVST 518
Query 154 LQKKAKNLDAITTPDPTTN---ASLLTKLQAQNQWLQD 188
L+ + ++L ++ N + L +L+ N L+
Sbjct 519 LKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRT 556
>sp|P35978|KINH_STRPU Kinesin heavy chain OS=Strongylocentrotus
purpuratus OX=7668 PE=2 SV=1
Length=1031
Score = 33.1 bits (74), Expect = 1.7, Method: Composition-based stats.
Identities = 26/171 (15%), Positives = 61/171 (36%), Gaps = 5/171 (3%)
Query 21 VLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCES 80
++ + G AA + + + E++D++ +S ++ E S C+
Sbjct 541 MMASLLKDLGEIGTALGGNAADMKPNVENIEKVDEEFTMARLFVSKMKTEVKTMSQRCKI 600
Query 81 SKEALAENNLNL-PKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQ 139
+ + AEN + E D C + E + + + E E +L++
Sbjct 601 LEASNAENETKIRTSEDELDSCRMTIQQHEAKMKSLSENIRETEGKKRHLEDSL--DMLN 658
Query 140 ARAVQMSTKVLIQFLQKKAKNLDAITTPDPTT--NASLLTKLQAQNQWLQD 188
V++ I+ ++ K + T AS+ ++++ Q
Sbjct 659 EEIVKLRAAEEIRLTDQEDKKREEEDKMQSATEMQASMSEQMESHRDAHQK 709
>sp|Q5B4E7|PPID_EMENI Peptidyl-prolyl cis-trans isomerase D OS=Emericella
nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46
/ NRRL 194 / M139) OX=227321 GN=cpr6 PE=3 SV=1
Length=372
Score = 32.7 bits (73), Expect = 2.1, Method: Composition-based stats.
Identities = 16/71 (23%), Positives = 28/71 (39%), Gaps = 11/71 (15%)
Query 115 IITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNAS 174
I GL +++ L YL N F EE + L+ + K+L + + A+
Sbjct 231 IALGLEKYQKGLRYL-NEFPEPEENDP----------KDLEPQMKSLRFTLHSNSSLLAN 279
Query 175 LLTKLQAQNQW 185
L + + W
Sbjct 280 KLGQFKNGKTW 290
>sp|C4ULG3|AFP18_YERRA Toxin Afp18 OS=Yersinia ruckeri serotype
O1 (strain ATCC 29473 / DSM 18506 / JCM 15110 / NCIMB 2194
/ NCTC 12986 / 2396-61) OX=527005 GN=afp18 PE=1 SV=1
Length=2123
Score = 33.1 bits (74), Expect = 2.4, Method: Composition-based stats.
Identities = 20/89 (22%), Positives = 41/89 (46%), Gaps = 5/89 (6%)
Query 124 VYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQN 183
++ E +Q+ ++ + L+Q L+ + N TT P T A +L +++
Sbjct 634 LFFEVIQHYLP---LLSKETDPQGERLLQRLRLEVSNAAEGTTVYPATMAEILAGMKSTE 690
Query 184 QWLQDMTTHLILRSFKEFLQSSLRALRQM 212
Q ++D + +LR FL + L ++ M
Sbjct 691 QAIRDWSGRKLLRVV--FLAACLEGVKLM 717
>sp|P70335|ROCK1_MOUSE Rho-associated protein kinase 1 OS=Mus
musculus OX=10090 GN=Rock1 PE=1 SV=1
Length=1354
Score = 32.7 bits (73), Expect = 2.6, Method: Composition-based stats.
Identities = 28/164 (17%), Positives = 60/164 (37%), Gaps = 18/164 (11%)
Query 29 PVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAEN 88
P +++ + + S ++ ++ L L+ E C +S
Sbjct 407 PSANASENRSSSNVDKSLQESLQKTIYKLEEQLHNEMQLKDEM---EQKCRTS------- 456
Query 89 NLNLPK-MAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMST 147
NL L K M E D N E+ + +I ++ L++ N ++ EQ + +
Sbjct 457 NLKLDKIMKELDEEGNQRRNLESAVSQIEKE----KMLLQHRINEYQRKVEQENEKRRNI 512
Query 148 KVLIQFLQKKAKNLDAITTPDPTTN---ASLLTKLQAQNQWLQD 188
+ + L+ + ++L + N L +L+ N L+
Sbjct 513 ENEVSTLKDQLEDLRKASQTSQLANEKLTQLQKQLEEANDLLRT 556
>sp|B9GE13|KN12F_ORYSJ Kinesin-like protein KIN-12F OS=Oryza sativa
subsp. japonica OX=39947 GN=KIN12F PE=3 SV=1
Length=2798
Score = 32.7 bits (73), Expect = 3.0, Method: Composition-based stats.
Identities = 34/202 (17%), Positives = 66/202 (33%), Gaps = 37/202 (18%)
Query 23 PAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCN--------K 74
P FP S+++ + E K R I+ L+ E N
Sbjct 784 PNNFPTNFELKRTSQELETCRGELQACLEANKKLAR----EIADLQNELSNIHSSNREGH 839
Query 75 SNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFE 134
N+ E AL + + + P+ +KD CFQ GF + +L ++ L+ ++
Sbjct 840 PNVVEKFSSALNQYDSHAPE--KKDQCFQEGF------MINTDDILNLQLELDIIKTILA 891
Query 135 SSEEQARAVQMSTKVL-----------------IQFLQKKAKNLDAITTPDPTTNASLLT 177
V+ L + +Q++ + ++ + L+
Sbjct 892 EERTTRAEVEKRITCLDDELKAANIHILQTCRQSETMQRELSDARSVIEALESQQIMLIN 951
Query 178 KLQAQNQWLQDMTTHLILRSFK 199
+L + Q HL R +
Sbjct 952 ELDELKESNQQSLEHLKKRDLE 973
>sp|P33176|KINH_HUMAN Kinesin-1 heavy chain OS=Homo sapiens OX=9606
GN=KIF5B PE=1 SV=1
Length=963
Score = 32.3 bits (72), Expect = 3.5, Method: Composition-based stats.
Identities = 24/127 (19%), Positives = 48/127 (38%), Gaps = 10/127 (8%)
Query 64 ISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFE 123
IS ++ E C+ + E+N KM E + C ++I + +
Sbjct 594 ISKMKSEVKTMVKRCKQLESTQTESN---KKMEENEK------ELAACQLRISQHEAKIK 644
Query 124 VYLEYLQNRFESSEEQARAVQMSTKVLIQF-LQKKAKNLDAITTPDPTTNASLLTKLQAQ 182
EYLQN + + +V ++ L+Q Q+K ++ T + ++ Q
Sbjct 645 SLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQ 704
Query 183 NQWLQDM 189
Q ++
Sbjct 705 IQSHRET 711
>sp|O77819|ROCK1_RABIT Rho-associated protein kinase 1 OS=Oryctolagus
cuniculus OX=9986 GN=ROCK1 PE=1 SV=1
Length=1354
Score = 32.3 bits (72), Expect = 3.7, Method: Composition-based stats.
Identities = 28/160 (18%), Positives = 65/160 (41%), Gaps = 17/160 (11%)
Query 42 PHRQPLTSSERIDKQIRYILDG---------ISALRKETCNKSNMCESSKEALAENNLNL 92
+R+ L+ + D + +D I L ++ N+ + + ++ +N+ L
Sbjct 401 SNRRYLSPANPNDNRTSSNVDKSLQENLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKL 460
Query 93 PK-MAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLI 151
K M E D N E+ + +I ++ L++ N ++ EQ + + + +
Sbjct 461 DKIMKELDEEGNQRRNLESTVSQIEKE----KMLLQHRINEYQRKAEQENEKRRNVENEV 516
Query 152 QFLQKKAKNLDAITTPDPTTN---ASLLTKLQAQNQWLQD 188
L+ + ++L ++ N A L +L+ N L+
Sbjct 517 STLKDQLEDLKKVSQNSQLANEKLAQLQKQLEEANDLLRT 556
>sp|Q83BT4|NRDR_COXBU Transcriptional repressor NrdR OS=Coxiella
burnetii (strain RSA 493 / Nine Mile phase I) OX=227377 GN=nrdR
PE=3 SV=1
Length=157
Score = 31.2 bits (69), Expect = 3.9, Method: Composition-based stats.
Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 26/104 (25%)
Query 77 MCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESS 136
C+ LNLP++ ++DG +S F+EE K+ GL L+ L+ R S
Sbjct 33 KCQERFTTFETAELNLPRIIKRDG-RRSAFDEE----KLRAGL------LKALEKR-PIS 80
Query 137 EEQARAV--------------QMSTKVLIQFLQKKAKNLDAITT 166
EQ ++S++ L + + + + LD +
Sbjct 81 TEQIETAVQRIIHKLRARGECEVSSQWLGELVMDELRALDEVAY 124
>sp|A9N8T7|NRDR_COXBR Transcriptional repressor NrdR OS=Coxiella
burnetii (strain RSA 331 / Henzerling II) OX=360115 GN=nrdR
PE=3 SV=1
Length=157
Score = 31.2 bits (69), Expect = 3.9, Method: Composition-based stats.
Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 26/104 (25%)
Query 77 MCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESS 136
C+ LNLP++ ++DG +S F+EE K+ GL L+ L+ R S
Sbjct 33 KCQERFTTFETAELNLPRIIKRDG-RRSAFDEE----KLRAGL------LKALEKR-PIS 80
Query 137 EEQARAV--------------QMSTKVLIQFLQKKAKNLDAITT 166
EQ ++S++ L + + + + LD +
Sbjct 81 TEQIETAVQRIIHKLRARGECEVSSQWLGELVMDELRALDEVAY 124
>sp|A9KBN5|NRDR_COXBN Transcriptional repressor NrdR OS=Coxiella
burnetii (strain Dugway 5J108-111) OX=434922 GN=nrdR PE=3
SV=1
Length=157
Score = 31.2 bits (69), Expect = 3.9, Method: Composition-based stats.
Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 26/104 (25%)
Query 77 MCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESS 136
C+ LNLP++ ++DG +S F+EE K+ GL L+ L+ R S
Sbjct 33 KCQERFTTFETAELNLPRIIKRDG-RRSAFDEE----KLRAGL------LKALEKR-PIS 80
Query 137 EEQARAV--------------QMSTKVLIQFLQKKAKNLDAITT 166
EQ ++S++ L + + + + LD +
Sbjct 81 TEQIETAVQRIIHKLRARGECEVSSQWLGELVMDELRALDEVAY 124
>sp|B6IZ81|NRDR_COXB2 Transcriptional repressor NrdR OS=Coxiella
burnetii (strain CbuG_Q212) OX=434923 GN=nrdR PE=3 SV=1
Length=157
Score = 31.2 bits (69), Expect = 3.9, Method: Composition-based stats.
Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 26/104 (25%)
Query 77 MCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESS 136
C+ LNLP++ ++DG +S F+EE K+ GL L+ L+ R S
Sbjct 33 KCQERFTTFETAELNLPRIIKRDG-RRSAFDEE----KLRAGL------LKALEKR-PIS 80
Query 137 EEQARAV--------------QMSTKVLIQFLQKKAKNLDAITT 166
EQ ++S++ L + + + + LD +
Sbjct 81 TEQIETAVQRIIHKLRARGECEVSSQWLGELVMDELRALDEVAY 124
>sp|B6J8Q8|NRDR_COXB1 Transcriptional repressor NrdR OS=Coxiella
burnetii (strain CbuK_Q154) OX=434924 GN=nrdR PE=3 SV=1
Length=157
Score = 31.2 bits (69), Expect = 3.9, Method: Composition-based stats.
Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 26/104 (25%)
Query 77 MCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESS 136
C+ LNLP++ ++DG +S F+EE K+ GL L+ L+ R S
Sbjct 33 KCQERFTTFETAELNLPRIIKRDG-RRSAFDEE----KLRAGL------LKALEKR-PIS 80
Query 137 EEQARAV--------------QMSTKVLIQFLQKKAKNLDAITT 166
EQ ++S++ L + + + + LD +
Sbjct 81 TEQIETAVQRIIHKLRARGECEVSSQWLGELVMDELRALDEVAY 124
>sp|P0CF95|BICL1_DANRE BICD family-like cargo adapter 1 OS=Danio
rerio OX=7955 GN=bicdl1 PE=2 SV=1
Length=569
Score = 32.0 bits (71), Expect = 4.4, Method: Composition-based stats.
Identities = 23/120 (19%), Positives = 47/120 (39%), Gaps = 17/120 (14%)
Query 32 PGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETC---NKSNMCESSKEALAEN 88
+D K+ + Q +T E + +IR + + L + C ++ +++ E L E
Sbjct 214 LRDDFKEKSISSNQHMTRLETLQAEIRMLSERKQDLERRVCAVLEENQQLQNTVEELRER 273
Query 89 NLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTK 148
L L K C L KI L E + + L+ + +++ + + T+
Sbjct 274 TLELEK-----HCHHKD------LQKI---LPETLLTIIKLKTNYSQKKKKTEHLILHTR 319
>sp|P39723|MBO1_YEAST Gamma tubulin complex adapter SPC72 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=SPC72 PE=1 SV=2
Length=622
Score = 31.2 bits (69), Expect = 7.4, Method: Composition-based stats.
Identities = 17/90 (19%), Positives = 37/90 (41%), Gaps = 4/90 (4%)
Query 121 EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ 180
E++ L+++Q E+SE + ++ ++ +N + T
Sbjct 129 EYQDTLQFVQENLENSESIVNTINHLLSFILTHFNEQDENAHLLD--KEERETLEETLEL 186
Query 181 AQNQWLQDMTT--HLILRSFKEFLQSSLRA 208
+ + L+ M T I++ ++FL S RA
Sbjct 187 SSDYVLEKMDTLSKFIIQFLQDFLHSKSRA 216
>sp|P61584|ROCK1_PANTR Rho-associated protein kinase 1 (Fragment)
OS=Pan troglodytes OX=9598 GN=ROCK1 PE=3 SV=1
Length=1003
Score = 31.2 bits (69), Expect = 8.0, Method: Composition-based stats.
Identities = 27/158 (17%), Positives = 61/158 (39%), Gaps = 18/158 (11%)
Query 35 DSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPK 94
D++ + + S ++ ++ L L+ E C +S N+ L K
Sbjct 62 DNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEM---EQKCRTS-------NIKLDK 111
Query 95 -MAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQF 153
M E D N E+ + +I ++ L++ N ++ EQ + + + +
Sbjct 112 IMKELDEEGNQRRNLESTVSQIEKE----KMLLQHRINEYQRKAEQENEKRRNVENEVST 167
Query 154 LQKKAKNLDAITTPDPTTN---ASLLTKLQAQNQWLQD 188
L+ + ++L ++ N + L +L+ N L+
Sbjct 168 LKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRT 205
>sp|B0BMJ2|CC42M_XENTR Coiled-coil domain-containing protein 42
like-2 OS=Xenopus tropicalis OX=8364 GN=TNeu058c09.1 PE=2
SV=2
Length=314
Score = 30.8 bits (68), Expect = 9.4, Method: Composition-based stats.
Identities = 22/140 (16%), Positives = 55/140 (39%), Gaps = 18/140 (13%)
Query 51 ERIDKQIRYILDGISALR--KETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNE 108
+ + ++ +L+ + +E ++ N +++ L + +L ++AE++ + E
Sbjct 141 SKYQQYLQRVLERTDEFQEVQEMIDRFNTLMATQNKLLKRDLENQELAEREKARLLHYQE 200
Query 109 ETC----------------LVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQ 152
ET L ++ ++E +QN + + ++MST L Q
Sbjct 201 ETRSQILELNNQIAQLQGELERVRAVAFQWESRWAQIQNTAAENTLRLGRIRMSTLNLFQ 260
Query 153 FLQKKAKNLDAITTPDPTTN 172
+ K+ + I+ D
Sbjct 261 TISKQMRLKTEISVEDTEAQ 280
Lambda K H a alpha
0.318 0.137 0.362 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0419 0.140 1.90 42.6 43.6
Effective search space used: 14070229470
Database: uniprot_sprot.fasta
Posted date: Apr 3, 2024 12:05 PM
Number of letters in database: 206,678,396
Number of sequences in database: 571,282
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40