Protein Model on 8pfi_A_1_O_1
(TEMPLATE: 
8pfi
)Protein Model on 8pfi_A_1_O_1
(TEMPLATE: 8pfi
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ALL MOLECULES IN THE BIOLOGICAL UNIT: |
| MOLECULES | contact sites | |||||
| model | mark | query | asym_id oper (auth_asym_id) |
type | description | a(query A) |
| 1 | a | A(TLR3_HUMAN) | A 1 (A) | polymer(polypeptide(L)) [733 aa] | Toll-like receptor 8 :TLR8_HUMAN | |
| 2 | b | O 1 (A) | non-polymer(YHG) | (3~{S})-~{N}-[4-[[5-(1,6-dimethylpyrazolo[3,4-b]pyridin-4-yl)-3-methyl-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridin-1-yl]methyl]-1-bicyclo[2.2.2]octanyl]morpholine-3-carboxamide | 217F 307Y(F) 309N(Y) 310I 332S(G) 334T(V) 364D(I) 366D(F) 416K(L) (identity: 22.2 %/30.7 %) | |
| ALIGNMENTS |
| MODEL[1] Protein A "queryA" TEMPLATE:8pfi_A_1 identity=30.7% |
queryA 34:VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTF: 119
: * ** * ** * * * * * ** * * * * * * * * :
8pfi_A_1 20:IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXXXXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---: 116
SecStr :EEE SS SS S S TT SEEE SS EE TTSS S TT EEE SS ------------- EE TTSSTT SS EEE SS SS T---:
ExpBur :bbebeebebeebbeebbeebbebebbebebeebeeebbeebeebeebbbbebee-------------ebebeebbbeebeebeebbbbebebeebbe---:
queryA 120:AFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL-------SSTKLGTQVQLEN---------------------LQELLLSNNKIQALKSEEL: 191
: **** * * * * ** * * * * * * * * *** * * :
8pfi_A_1 117:GLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFXXXCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDF: 216
SecStr :T TT SEEE SS EE TTTTTT TT EEE TTSS --- EE TTTTTT TT EEE SS SS SS TT SEEE TTS EE TTTT:
ExpBur :ebbebbbebbbbebebeebeeebbbebeebbebebbbbbbe---eeebeeeebbbeebeebebbbbbbbbbeebbeebbebbeebebbbbebeebbeeeb:
queryA 192:DIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NVV: 289
: * * * ** * * ** * * * * * * ** * * * *** * * :
8pfi_A_1 217:KGLINLTL--LDLSGN-----CPRCFNAPFPCVP-----CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEIA: 302
SecStr :TT TT E--EE TTS-----S SS SS ----- TTS EE TTTTSS TT EEE SS S GGGGTT T--T EEE SS HHHHH:
ExpBur :bebeebeb--bbbbbb-----bbbeeeeebeeee-----beeeeebebeeebbeebeebeebbbbbbbbeebebbbbeebe--ebebbbbbbbebbebbe:
Contact : b
queryA 290:GNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK: 382
: ** ** * * * ** * * * * * * * *** * * * * * * * ** :
8pfi_A_1 303:SGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL------REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLE: 395
SecStr :T GGGGG TT EEE S TT SS GGGGG TT EEE -TT SEE------ TTTTGGGTT SS EEE S EE GGGGTT SS :
ExpBur :ebebbeebeebeebbbbbbeeeeeeeeebebbeebeebeebebbbb-bbbbbbeb------eeebbebbbebeebebbbbbebebeebebbbbeebeebe:
Contact : b bbbbb b b b b
queryA 383:YLSLS---------------------------------------NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI: 443
: ** * * * * * * * * * * * * * :
8pfi_A_1 396:IIYLSENRISPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFIGPNQFENLPDIACLNLSANSN: 491
SecStr :EEE SS ----------------------------- TTS SSS S SS HHHHTTSEE----EE SS SS TTTTTT EEEEE SS :
ExpBur :ebbbbebebee-----------------------------eeeeeebbeeeebbeeebeeeeeb----bbbbebebeebbeebbeebbebbbbbbbebeb:
Contact : b b
queryA 444:GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPF------------QPLRNLTILDLSNNNIANINDDM-LEGLE: 530
: * * * * *** ** * * * * ** * ** *** * ** :
8pfi_A_1 492:AQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFXXXXXTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKS: 583
SecStr : B S TTSSSTT --------SEEE SS B STTTTTT TT EEE TT TTT ----- GGGGG SS EEE TT S S EESS:
ExpBur :ebebebebbeebeeb--------ebbbbbebebebbeeebbbbbeebebbbbbebeebb-----ebbbebbeebeebeebbbbebebeebeebeebebeb:
queryA 531:KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELKIID----------------------------------: 592
: * * * ** * *** * * * * ** * * * ** * * :
8pfi_A_1 584:LVELV-FSGNRLDILWXXXXXRY-ISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSL: 681
SecStr : EEE- TTS HHHH ----- -TTTTTEETT EEE SS S HHHHHTS TT SEEE SS S GGGGGG TT EEE SS S G:
ExpBur :beebb-bbbbbbeebb-----eb-eebbeebeebeebbbbebebeebeeebbebbbebbeebbbbebebeebebebbeebeebebbbbeebebeebbeeb:
queryA 593:-----------LGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE-THTNIPELSSHYLCNT: 679
: * * ** *** * * ** * * * *** *** * * * * ** * * :
8pfi_A_1 682:SDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDEHLNVKIPRLVD-VICAS: 779
SecStr :GGT SS EEE SS TTSSSS TT EEE SS TTTS SS EEE TT EE SGG-GHHHHHHHHH SSSB GGG-SBEEE:
ExpBur :eeebebbbebbbbebebeebbeebbbebeebbbbbbbebebeebeeebbeeeeebebeebbbbebebebeee-beebbbbbeeeeebebeebbb-bebee:
queryA 680:PPHYHG: 685
:* *:
8pfi_A_1 780:PGDQRG: 785
SecStr :STTTBT:
ExpBur :eeeebe:
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[assembly_id:1]
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