Protein Model on 7r54_B_1_O_1 (TEMPLATE: 7r54 )

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ALL MOLECULES IN THE BIOLOGICAL UNIT:
[assembly_id:1]

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MOLECULES contact sites
model mark query asym_id oper
(auth_asym_id)		 type description a(query A)
1 a A(TLR3_HUMAN) B 1 (B) polymer(polypeptide(L)) [734 aa] Toll-like receptor 8 :TLR8_HUMAN
2 b O 1 (A) non-polymer(I5B) (5-methoxy-6-pyridin-4-yl-1~{H}-indazol-3-yl)-(4-methylpiperazin-1-yl)methanone 351F 353W(Y) 355K 356C(G) 388N(G) 390F(V) 416K(I) 418K(F) 440L(E) (identity: 22.2 %/29.1 %)
ALIGNMENTS
MODEL[1] Protein A "queryA" TEMPLATE:7r54_B_1 identity=29.1%
queryA        34:VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN: 133
                : * **   *  **       * * *  *         *     **      *      *                *      *  *    ** ** *  *:
7r54_B_1      20:IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHN------PNXXXXXXXXXXXXXGLN----ITDGAFLNLKNLRELLLEDN: 109
SecStr          :EEE  SS  SS  S S TT SEEE  SS   EE TTTTTT TT  EEE  S ------  -------------  E----E TTSSTT TT  EEE  SS:    
ExpBur          :bbebeebebeebbeebbeebbebebbebebeebeeebbeebeebeebbbbeb------ee-------------ebe----beebbbeebeebeebbbbeb:    

queryA       134:SIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGR---LFGLFLNN: 230
                :    *   *      *  * *  *            * **  * *  *       *   *                     * *        *   *   :
7r54_B_1     110:QLPQI---PSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYXXXXCEKTNI-------------------EDGVFETLTNLELLSLSFNSL: 187
SecStr          :  SS --- SS  TT SEEE  SS   EE TTTTTT TT  EEE  SS  ----  S EE------------------- TTTTTT TT  EEE  SS  :    
ExpBur          :ebeeb---beebbebbbebbbbebebeebeeebbbebeebeebebbebbe----eeebeb-------------------bebbbeebeebebbbbbbbbb:    

queryA       231:VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN------------------NLNVVGNDSFAW--LPQLEYFFLEYNNI: 310
                :    * *           * * * *** *    *   * **   *** **** *                    *    * **   * ** *  *     :
7r54_B_1     188:SHVPPKLP---------SSLRKLFLSNTQIKYISEEDFKGL--INLTLLDLSGNCPRCFNAPFPCVPCDGGASINI---DRFAFQNLTQLRYLNLSSTSL: 273
SecStr          :SS  SS  ---------TT  EEE TT    EE GGGGTT --TT  EEE TTSS   SS SS     SSS   EE--- TTTTTT TT  EEE  SS  :    
ExpBur          :eebbeebb---------eebeebebbbbebeebeeeebeeb--eebbbbbbbbbbbbeeeeebeeeebeeeeebeb---ebebbbebeebeebbbbbbbb:    

queryA       311:QHLFSHSLHGLFNVRYLNLKRSFTKQSIS----LASLPKID--DFSFQWLKC--LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFV: 402
                :                * *        *     *  **     * **   *     * *   *         *  *  *  * *         *    * :
7r54_B_1     274:RKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRN---------FSKLLSLRALHLRGYV--FQELREDDFQ: 362
SecStr          :S   GGGGTT TT  EEE  SS  HHHHHH SGGGG TT  EEE  S   TT   SS    GG---------GGG TT  EEE TT  -- SEE GGGGG:    
ExpBur          :eebeeebbeebeebebbbbbbbebbebbeebebbeebeebeebbbbbbeeeeeeeeebebbee---------beebeebebbbbebbb--bbebeeebbe:    
Contact         :                                              b b bb                                 b b            

queryA       403:SLAHSP-LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL----------------------ENIFEIY--------LSYNKYLQL: 471
                : *   * *   **  * *  *    *     **   *  * *                                   *               * * * *:
7r54_B_1     363:PLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXXXXXXXXXXXXXXXXXXXXXXXDPHSNFYHFTRPLIKPQCAAYGKALDL: 462
SecStr          :GGTT SS  EEE  S   SEE GGGGTT SS  EEE  SS     ---------------------------- TTS SSS  S SS HHHHTTSEEEE :    
ExpBur          :bbbebeebebbbbbbbebeebebebbeebeebeebbbbebebebe----------------------------eeeeeebbbeeebbeeebeeeeebbbb:    
Contact         :              b b                     b                                                             

queryA       472:TRNSFALVPSLQRLMLRRVALKNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHL: 564
                :  **       *   *   *  *          *   *        *** **     *   *  *  ** ***  *        *       *      *:
7r54_B_1     463:SLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYN--SHYFRIAGVTHHLEFIQNFTNL: 560
SecStr          : SSS SS  TTTTTT   EEEEE  SS    B  S TTTTSTT  EEE  SS  B  STTTTTT TT  EEE TT --  SS  TTTSS  GGGGG SS :    
ExpBur          :bebebeebbeebbeebbebbbbbbbebebbbebebebbeebeebebbbbbebbbbbbeeebbbbbeebbbbbbbeb--ebeeeeeeebbbbebbeebeeb:    

queryA       565:HILNLESNGF-------------------------------DEIPVEVFKDLFELKIIDLGLNNLNTLPASVF-NNQVSLKSLNLQKNLITSVEKKVFGP: 632
                :  ***  *                                 *      ** *  *   ** ** *   *   * *   **  *    *            :
7r54_B_1     561:KVLNLSHNNIYTLTXKYNLESKSLVELVFSGNRLDILWXXXDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQ-: 659
SecStr          : EEE TT       -  S   SS  EEE TTS HHHH --- TTSTTTTTT TT  EEE  SS  S   HHHHHTS TT SEEE  SS  S   GGGGG-:    
ExpBur          :eebebbebebeebb-eeebebebbeebbbbebbbeebb---eeebbebbebbeebeebbbbebebeebeeebbebbbebbeebbbbebebeebebebbe-:    

queryA       633:AFRNLTELDMRFNPFDCTCESIAWFVNWINE---THTNIPELSS: 673
                : *  *  ** * *       *   *          *  *  * *:
7r54_B_1     660:QFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPS: 703
SecStr          :G TT  EEE  S       S HHHH SS  EEE  SS       :    
ExpBur          :ebeebebbbbeebebeebbeeeeebbeebebbbbbebebeeebe:

Input Residue Numbers for Focused Sites

ex) 2,15,123