Protein Model on 7r53_B_1_O_1 (TEMPLATE: 7r53 )

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ALL MOLECULES IN THE BIOLOGICAL UNIT:
[assembly_id:1]

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MOLECULES contact sites
model mark query asym_id oper
(auth_asym_id)		 type description a(query A)
1 a A(TLR3_HUMAN) B 1 (B) polymer(polypeptide(L)) [736 aa] Toll-like receptor 8 :TLR8_HUMAN
2 b O 1 (A) non-polymer(I5N) 5-cyclopropyl-6-(2,6-dimethylpyridin-4-yl)-~{N}-[(3~{R},4~{R})-3-fluoranylpiperidin-4-yl]-1~{H}-indazol-3-amine 217F 307Y(F) 309N(Y) 310I 332S(G) 334T(V) 366D(F) (identity: 28.6 %/31.5 %)
ALIGNMENTS
MODEL[1] Protein A "queryA" TEMPLATE:7r53_B_1 identity=31.5%
queryA        34:VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTF: 119
                : * **   *  **       * * *  *         *     **      *                          *  *  * *  * * *      :
7r53_B_1      20:IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXXXXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---: 116
SecStr          :EEE  SS  SS  S S TT SEEE  SS   EE TTSS S TT  EEE  SSS  ------------  EE TTTTSS TT  EEE  SS  SS  S---:    
ExpBur          :bbebeebebeebbeebeeebbebebbebebeebeeebbeebeebeebbbbebeee------------ebebeeebbeebeebeebbbbebebeebbe---:    

queryA       120:AFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL-------SSTKLGTQVQLEN---------------------LQELLLSNNKIQALKSEEL: 191
                :     **** *  * *  *         **  * *  *              *    * *                     *  * ***  *     *  :
7r53_B_1     117:GLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNXXXXXXXXKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDF: 216
SecStr          :S  TT SEEE  SS   EE TTTSTT TT SEEE    --------  EE TTSGGG TT  EEE  SS   S  SS  TT  EEE TTS   EE GGGS:    
ExpBur          :ebbebbbebbbbebebeebeeebbbebeebebbebbeb--------ebeebebbbeebeebebbbbbebebeebbeebbeebeebebbbbebeebeeeeb:    

queryA       192:DIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NVV: 289
                :    *  *  * ** *      * ** *              * *           *  * * **   *       *       *  ***  * *     :
7r53_B_1     217:KGLINLTL--LDLSGN-----CPRCFNAPFPCVP-----CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEIA: 302
SecStr          :SS TT  E--EE TTS-----S   SS SS    ----- SSS   EE TTTTTT TT  EEE  SS  S   GGGGTT T--T  EEE  SS  HHHHH:    
ExpBur          :eebeebbb--bbbbbb-----bbbeeeeebeeee-----beeeeebebeeebbeebeebeebbbbbbbbeebeebbbeebe--ebebbbbbbbebeebbe:    
Contact         :                         b                                                                          

queryA       290:GNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK: 382
                :       ** **   *  * *     **   *     *   * * * *    *          ***     *  *   *   * *  *    *    ** :
7r53_B_1     303:SGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL------REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLE: 395
SecStr          :H GGGGG TT  EEE  S   TT   SS    GGGGG TT  EEE -TT   SEE------ TGGGGGGTT SS  EEE  S   SEE GGGGGG SS  :    
ExpBur          :ebebbeebeebeebbbbbbeeeeeeeeebebbeebebbeebebbbb-bbbbbbeb------eeebbebbbebeebebbbbbbbebeebebebbeebeebe:    
Contact         :                 b bbbbb                        b b                                b                

queryA       383:YLSLS-NSFTSLRTLTNETFVSL------------------AHS-------PL---------HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQEL: 447
                :   ** *    *                              **       **           * *  * *  *    *  *     * *  *   * *:
7r53_B_1     396:IIYLSENRISPLXXXXXXXXXXXXXXXXXXXXXXXXXXXXDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVL: 495
SecStr          :EEE TT      ---------------------------- TTS SSS  S SS HHHHTTSEEEE  SSS SS  TTSSTT   EEEEE  SS    B :    
ExpBur          :ebbbbebebebe----------------------------eeeeeebbeeeebbeeebeeeeebbbbbebebeebbeebbeebbebbbbbbbebebbbeb:    
Contact         :     b                                                                                              

queryA       448:TGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLEI: 534
                : * *               *** ** *   *     *  *    *              *       *   **  * ** ***    *   **     * :
7r53_B_1     496:SGTEFSAIPHV--------KYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVEL: 587
SecStr          : S TTSSSTT --------SEEE  S   B  STTTTTT TT  EEE TT   SS  TTTSS  GGGGG SS  EEE TTS      SS S B SS  EE:    
ExpBur          :eeebbeebeeb--------ebbbbbebebbbbeeebbbbbeebbbbbbbebebeeeeeeebbbbbbbeebeebeebbbbebebeebbebebbebebbeeb:    

queryA       535:LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELKIID--------------------------------------: 592
                :     * *  **        *   ***  *  * *  *    ** * *      * ** * *                                      :
7r53_B_1     588:V-FSGNRLDILWNXXXXRY-ISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFT: 685
SecStr          :E- TTS HHHHT ----  -TTSSTB TT  EEE  SS  S   HHHHHTS TT SEEE  SS  S   GGGGGG TT  EEE  SS      S GGGT :    
ExpBur          :b-bbebebeebbe----eb-eebbebbeebeebbbbebebeebbeebbebbbebbeebbbbebebeebebebbeebeebebbbbeebebeebbeebeebb:    

queryA       593:-------LGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE-THTNIPELSSHYLCNTPPHY: 683
                :       *  *    **        *** * *  **     *          *  *    *** ***  *  *  *  *     ** *     *  *   :
7r53_B_1     686:SSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDEHLNVKIPRLVD-VICASPGDQ: 783
SecStr          :S   EEE  SS      TTHHHH TT  EEE TTS      TTTT  SS     EEE TT  EE SGG-GHHHHHHHHH TTSB   GGG- BEEESTTT:    
ExpBur          :ebbbebbbbebebeebbebbbbebeebebbbbbebebeebeeebbeeeeeeebeebbbbebebebeee-beebbebbeebeebebeebbb-bebeeeeeb:    

queryA       684:HG: 685
                : *:
7r53_B_1     784:RG: 785
SecStr          :BT:    
ExpBur          :ee:

Input Residue Numbers for Focused Sites

ex) 2,15,123