Protein Model on 6ty5_B_1_O_1 (TEMPLATE: 6ty5 )

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ALL MOLECULES IN THE BIOLOGICAL UNIT:
[assembly_id:2]

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MOLECULES contact sites
model mark query asym_id oper
(auth_asym_id)		 type description a(query A)
1 a A(TLR8_HUMAN) B 1 (B) polymer(polypeptide(L)) [743 aa] Toll-like receptor 8 :TLR8_HUMAN
2 b O 1 (B) non-polymer(O0W) 5-methyl-7-(7-methyl-2-piperidin-4-yl-indazol-5-yl)furo[3,2-c]pyridin-4-one 261F 346F 348Y 349I 350K 351G 352S 378V 403I 405F 427E (identity: 100.0 %/94.3 %)
ALIGNMENTS
MODEL[1] Protein A "queryA" TEMPLATE:6ty5_B_1 identity=94.3%
queryA        31:SRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNLREL: 130
                :*********************************************************************             ******************:
6ty5_B_1       5:SRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXXXXXXXXXGLNITDGAFLNLKNLREL: 104
SecStr          :   SS EEEEETTEEEEE  SS  SS  S S TT SEEE TTS   EE TTTTTT TT  EEE  S   -------------  EE TTSSTT TT  EE:    
ExpBur          :ebeebbeeeeeeeeebbbbeebebeebbeebbeebbebebbebebeebeeebbeebeebeebbbbebee-------------ebebeebbbeebeebeeb:    

queryA       131:LLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLS: 230
                :****************************************************    ********************************************:
6ty5_B_1     105:LLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYXXXXCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLS: 204
SecStr          :E  SS  SS  SS  TT  EEE TTS   EE TTTTTT TT SEEE  SS  ----  S EE TTSSTT TT  EEE  SS  SS  SS  TT  EEE T:    
ExpBur          :bbbebebeebbeebbebbbebbbbebebeebeeebbbebeebebbbbbebbe----eeebeeeebbbeebeebebbbbbbbbbeebbeebbebbeebebb:    

queryA       231:NTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASG: 330
                :****************************************************************************************************:
6ty5_B_1     205:NTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASG: 304
SecStr          :TS   EE TTTTSS TT  EEE TTSS   SS SS     TTS   EE TTTTSS TT  EEE  SS  S   GGGGTT TT  EEE  SS  HHHHHS :    
ExpBur          :bbebeebbeeebeebeebbbbbbbbbbbbeeeeebeeeebeeeeebebeeebbeebeebeebbbbbbbbeebeebbbeebeebebbbbbbbebbebbeeb:    
Contact         :                              b                                                                     

queryA       331:AFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRI: 430
                :****************************************************************************************************:
6ty5_B_1     305:AFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRI: 404
SecStr          :GGGGG TT  EEE  S   TT   SB    GGGGG TT  EEE TT   SEE TTTTGGGTT SS  EEE  S   SEE GGGGTT SS  EEE  SS  :    
ExpBur          :ebbeebeebeebbbbbbeeeeeeeeebebbeebeebeebebbbbbbbbbbebeeebbebbbebeebebbbbbebebeebebebbeebeebeebbbbebeb:    
Contact         :               b bbbbb                         b                        b b                     b   

queryA       431:SPLVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIP: 530
                :****                           *********************************************************************:
6ty5_B_1     405:SPLVXXXXXXXXXXXXXXXXXXXXXXXXXXXDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIP: 504
SecStr          :    --------------------------- TTS SSS  S SS HHHHTTSEEEE  SSS SS  TTSSTT   EEEEE  SS    B  S TTSSST:    
ExpBur          :ebee---------------------------eeeeeebbeeeebbeeebeeeeebbbbbebebeebbeebbeebbebbbbbbbebebbbebebebbeebe:    

queryA       531:HVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNR: 630
                :********************************************************************** *****************************:
6ty5_B_1     505:HVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTXKYNLESKSLVELVFSGNRLDILWNDDDNR: 604
SecStr          :T SEEE  SS  B  STTTTTT TT  EEE TT   SS  TTTSS  GGGGG SS  EEE TT       -  S B SS  EEE TTS HHHHT SS  T:    
ExpBur          :ebebbbbbebebbbbeeebbbbbeebbbbbbbebebeeeeeeebbbbebbeebeebeebebbebebeebb-eeebebebbeebbbbebbbeebbeeeeee:    

queryA       631:YISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG: 730
                :****************************************************************************************************:
6ty5_B_1     605:YISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG: 704
SecStr          :TTTTTTB TT  EEE TTS  S   HHHHHTS TT SEEE  SS  S   GGGGGG TT  EEE  SS      S GGGT S   EEE  SS      TT:    
ExpBur          :bbebbebbeebeebbbbebebeebeeebbebbbeebbebbbbebebeebebebbeebebbebbbbeebebbebbeebeebbebbeebbbbebebeebbee:    

queryA       731:FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE: 818
                :****************************************************************************************:
6ty5_B_1     705:FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE: 792
SecStr          :SSTT SS  EEE TTS      HHHH  SS     EEE TT  EE SGGGHHHHHHHHH TTSB   GGG BEEE TTTTTSBTTS  :    
ExpBur          :bbbebeebebbbbbebebeebeeebbeeeeebebeebbbbebebebeeebeebbebbeeeeebebeebbebebeeeeeeeeebbbeee:

Input Residue Numbers for Focused Sites

ex) 2,15,123