Protein Model on 7r52_A_1_V_1 (TEMPLATE: 7r52 )

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ALL MOLECULES IN THE BIOLOGICAL UNIT:
[assembly_id:1]

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MOLECULES contact sites
model mark query asym_id oper
(auth_asym_id)		 type description a(query A)
1 a A(TLR8_HUMAN) A 1 (A) polymer(polypeptide(L)) [733 aa] Toll-like receptor 8 :TLR8_HUMAN
2 b V 1 (B) non-polymer(I6A) 5-methoxy-6-pyridin-4-yl-1~{H}-indole 346F 348Y 349I 350K 351G 352S 376G 378V 405F (identity: 100.0 %/93.0 %)
ALIGNMENTS
MODEL[1] Protein A "queryA" TEMPLATE:7r52_A_1 identity=93.0%
queryA        31:SRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNLREL: 130
                :*********************************************************************             ******************:
7r52_A_1       5:SRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXXXXXXXXXGLNITDGAFLNLKNLREL: 104
SecStr          :    SSEEE GGGSEEEE  SS  SS  TTS TTEEEEE  SS   EE TTSSTT TT  EEE  SS  -------------  EE TTSSTT TT  EE:    
ExpBur          :eeeebbeeeeeeeebebbbeebebeeebeebbeebbebebbebebeebeeebbeebeebebbebbebee-------------ebebeebbbeebeebeeb:    

queryA       131:LLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLS: 230
                :****************************************************    ********************************************:
7r52_A_1     105:LLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYXXXXCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLS: 204
SecStr          :E  SS  SS  SS  TT  EEE  SS   EE HHHHTT TT  EEE  SS  ----    EE TTTTTT TT  EEE  SS  SS  SS  TT  EEE T:    
ExpBur          :bbbebebeebbbebbebbbebbbbebebeebebebbbebeebebbebbebbe----eeebeeeeebbeebeebebbbbbbbbbeebbeebbeebbebebb:    

queryA       231:NTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASG: 330
                :****************************************************************************************************:
7r52_A_1     205:NTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASG: 304
SecStr          :TS   EE TTTTTT TT  EEE TTSS   SS SS     TTS   EE TTSSTT TT  EEE  SS  S   GGGGTT TT  EEE  SS  HHHHHS :    
ExpBur          :bbebeebebeebeebeebebbbbbbbbbbeeeeebeeeebeeeeebebeeebbeebeebeebbbbbbbbeebeeebbeebeebebbbbbbbebbebbeeb:    

queryA       331:AFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRI: 430
                :****************************************************************************************************:
7r52_A_1     305:AFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRI: 404
SecStr          :SGGGG TT  EEE  S   TT   SB    GGGGG TT  EEE TT   SEE TGGGTTTTT SS  EEE  S   SEE GGGGTT SS  EEE  SS  :    
ExpBur          :ebbeebeebeebbbbbbeeeeeeeeebebbeebebbeebebbbbbbbbbbebeeebbebbbebeebebbbbbebebeebebebbeebeebeebbbbebbb:    
Contact         :               b bbbbb                       b b                          b                         

queryA       431:SPLVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIP: 530
                :***                            *********************************************************************:
7r52_A_1     405:SPLXXXXXXXXXXXXXXXXXXXXXXXXXXXXDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIP: 504
SecStr          :   ---------------------------- TTS SSS  S SS HHHHTTSEEEE  SS  SS  TTSSTT   EEEEE  SS    B  S TTSSST:    
ExpBur          :ebe----------------------------eeeeeebbeeeeebeeebeeeeebbbbbebebeebbeebbeebbebbbbbbbebebebebebebbeebe:    

queryA       531:HVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNR: 630
                :************************************        ********************************************************:
7r52_A_1     505:HVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHXXXXXXXXHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNR: 604
SecStr          :T SEEE  SS  B  STTTTTT TT  EEE TT   --------   GGGGG SS  EEE TT       S  S   SS  EEE TTS HHHHS SS  T:    
ExpBur          :ebebbbbbebebebeeeebbbbbeebbbbbbbebee--------ebbebbeebeebeebebbebebeebeebeebebebbeebbbbbbbbeebbeeebee:    

queryA       631:YISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG: 730
                :****************************************************************************************************:
7r52_A_1     605:YISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG: 704
SecStr          :TTTTTTT TT  EEE TTS  S   HHHHHTS TT SEEE  SS  S   GGGGGG TT  EEE  SS      TTHHHH S   EEE  SS      TT:    
ExpBur          :beebbeebeebeebbbbebebeebeeebbebbbeebeebbbbebebeebebebbeebeebebbbbeebebeeebeebeeebebbebbbbbebebeebbee:    

queryA       731:FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE: 818
                :**  ************************************************************************************:
7r52_A_1     705:FLXXVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE: 792
SecStr          :  --  S  EEE TTS      TTTS   S     EEE TT  EE SGGGHHHHHHHHH TTSB   GGG BEEE TTTTTSBTTS  :    
ExpBur          :bb--eeebebbbbbebebeebeeebbeeeeebebeebbbeebebebeeebeebbbbbeeeeebebebbbebebeeeeeeeebbbbeee:

Input Residue Numbers for Focused Sites

ex) 2,15,123