Protein Model on 7r53_A_1_O_1 (TEMPLATE: 7r53 )

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ALL MOLECULES IN THE BIOLOGICAL UNIT:
[assembly_id:1]

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MOLECULES contact sites
model mark query asym_id oper
(auth_asym_id)		 type description a(query A)
1 a A(TLR8_HUMAN) A 1 (A) polymer(polypeptide(L)) [737 aa] Toll-like receptor 8 :TLR8_HUMAN
2 b O 1 (A) non-polymer(I5N) 5-cyclopropyl-6-(2,6-dimethylpyridin-4-yl)-~{N}-[(3~{R},4~{R})-3-fluoranylpiperidin-4-yl]-1~{H}-indazol-3-amine 494F 495F 516S 518A 567Y (identity: 100.0 %/93.5 %)
ALIGNMENTS
MODEL[1] Protein A "queryA" TEMPLATE:7r53_A_1 identity=93.5%
queryA        31:SRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNLREL: 130
                :**********************************************************************            ******************:
7r53_A_1       5:SRSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXXXXXXXXXGLNITDGAFLNLKNLREL: 104
SecStr          :    SSEEEE SSSEEEE  SS  SS  S S TT SEEE  SS   EE TTSS S TT  EEE  SSS  ------------  EE TTTTSS TT  EE:    
ExpBur          :ebeebbeeeeeeeeeebbbeebebeebbeebeeebbebebbebebeebeeebbeebeebeebbbbebeee------------ebebeeebbeebeebeeb:    

queryA       131:LLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLS: 230
                :**************************************************       *******************************************:
7r53_A_1     105:LLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNXXXXXXXEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLS: 204
SecStr          :E  SS  SS  SS  TT SEEE  SS   EE TTTSTT TT SEEE    -------   EE TTSGGG TT  EEE  SS   S  SS  TT  EEE T:    
ExpBur          :bbbebebeebbeebbebbbebbbbebebeebeeebbbebeebebbebbeb-------eebeebebbbeebeebebbbbbbbebeebbeebbeebeebebb:    

queryA       231:NTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASG: 330
                :****************************************************************************************************:
7r53_A_1     205:NTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASG: 304
SecStr          :TS   EE GGGSSS TT  EEE TTSS   SS SS     SSS   EE TTTTTT TT  EEE  SS  S   GGGGTT TT  EEE  SS  HHHHHH :    
ExpBur          :bbebeebeeeebeebeebbbbbbbbbbbbeeeeebeeeebeeeeebebeeebbeebeebeebbbbbbbbeebebbbbeebeebebbbbbbbebeebbeeb:    

queryA       331:AFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRI: 430
                :****************************************************************************************************:
7r53_A_1     305:AFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRI: 404
SecStr          :GGGGG TT  EEE  S   TT   SS    GGGGG TT  EEE TT   SEE GGGGGGGTT SS  EEE  S   SEE GGGGGT TT  EEE  SS  :    
ExpBur          :ebbeebeebeebbbbbbeeeeeeeeebebbeebebbeebebbbbbbbbbbebeeebbebbbebeebebbbbbbbebeebebbbbeebeebeebbbbebbb:    

queryA       431:SPLVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIP: 530
                :***                            *********************************************************************:
7r53_A_1     405:SPLXXXXXXXXXXXXXXXXXXXXXXXXXXXXDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIP: 504
SecStr          :   ---------------------------- TTS SSS  S SS HHHHTTSEEEE TTSS SS  TTSSTT   EEEEE TTS    B  S TTSSST:    
ExpBur          :ebe----------------------------eeeeeebbeebebbeeebbeeeebbbbbebebeebbeebbeebbebbbbbbbebebbbebebebbeebe:    
Contact         :                                                               bb                    b b            

queryA       531:HVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNR: 630
                :**********************************************************************    **************************:
7r53_A_1     505:HVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTXXXXLESKSLVELVFSGNRLDILWNDDDNR: 604
SecStr          :T SEEE  SS  B  STTTTTT TT  EEE TT   SS  TTTSS  GGGGG SS  EEE TTS      ---- B SS  EEE TTS HHHHS SS  T:    
ExpBur          :ebebbbbbebebbbbeeebbbbbeebbbbbbbebebeeeeeeebbebebbeebeebeebebbebebeebe----bebebbeebbbbebbbeebbeeeeee:    
Contact         :                                    b                                                               

queryA       631:YISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG: 730
                :****************************************************************************************************:
7r53_A_1     605:YISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG: 704
SecStr          :TTTSSTB TT  EEE  SS  S   HHHHHTS TT SEEE  SS  S   GGGGGG TT  EEE  SS      S GGGT S   EEE  SS      TT:    
ExpBur          :bbebbeebeebeebbbbebebeebeeebbebbbebbeebbbbebebeebebebbeebeebebbbbeebebeebbeebeebbebbbebbbbebebeebbeb:    

queryA       731:FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE: 818
                :****************************************************************************************:
7r53_A_1     705:FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE: 792
SecStr          :HHHH TT  EEE TTS      TTTT  SS     EEE TT  EE SGGGHHHHHHHHH TTSB   GGG BEEESTTTBTSBGGG  :    
ExpBur          :bbbebeebbbbbbbebebeebeeebbeeeeeeebeebbbbebebebeeebeebbebbeebeebebeebbebebeeeeebeeebbbeee:

Input Residue Numbers for Focused Sites

ex) 2,15,123