Protein Model on 5wyx_A_1_N_1 (TEMPLATE: 5wyx )

CurrentView:HTML5 Change to:[JAVA] DOWNLOAD:
[sequence-replaced 3D model] [for PyMOL]
[3D template]
[Modeller script]

ALL MOLECULES IN THE BIOLOGICAL UNIT:
[assembly_id:1]

Window size :
[small] [medium] [large]

[help]

MOLECULES contact sites
model mark query asym_id oper
(auth_asym_id)		 type description a(query A)
1 a A(TLR8_HUMAN) A 1 (A) polymer(polypeptide(L)) [750 aa] Toll-like receptor 8 :TLR8_HUMAN
2 b N 1 (B) non-polymer(CU8) 7-(3-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 261F 262N 346F 348Y 349I 350K 351G 352S 376G 378V 405F (identity: 100.0 %/95.3 %)
ALIGNMENTS
MODEL[1] Protein A "queryA" TEMPLATE:5wyx_A_1 identity=95.3%
queryA        32:RSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPGIQSNGLNITDGAFLNLKNLRELL: 131
                :*********************************************************************           ********************:
5wyx_A_1      10:RSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXXXXXXXXNGLNITDGAFLNLKNLRELL: 109
SecStr          :  SSSEEEEETTEEEEE  SS  SS  S   TTEEEEE  SS   EE TTSSTT TT  EEE TT S  -----------   EE TTTTTT TT  EEE:    
ExpBur          :eeebbbeeeeeeeebbebeebebeebbeebeeebbebebbebebeebeeebbeebeebeebbbbebeee-----------ebbebeebbbeebeebeebb:    

queryA       132:LEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSN: 231
                :****************************************************************************************************:
5wyx_A_1     110:LEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSN: 209
SecStr          :  SS  SS  SS  TT SEEE  SS   EE TTTTTT TT SEEE  SSS SSS   S EE TTTTTT TT  EEE  SS  SS  S   TT  EEE TT:    
ExpBur          :bbebebeebbbbbbebbebbbbbebebeebeeebbbebeebeebbbbbbbeeeeebeebebeebbbeebeebebbbbbbbbbeebbeebbebbeebebbe:    

queryA       232:TQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGA: 331
                :****************************************************************************************************:
5wyx_A_1     210:TQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGA: 309
SecStr          :S   EE TTTTTT TT  EEE TTSS   TT SS     STT   EE TTTTTT TT  EEE TTS  S   GGGGTT TT  EEE  SS  HHHHHS G:    
ExpBur          :bebeebbeeebeebeebbbbbbbbbbbbbeeeeeeeeebeeeeebebeeebbeebeebeebbbbbbbbeebeebbbeebeebebbbbbebebbebbeebe:    
Contact         :                             bb                                                                     

queryA       332:FLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRIS: 431
                :****************************************************************************************************:
5wyx_A_1     310:FLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRIS: 409
SecStr          :GGGG TT  EEE TT   TT   SB    GGGGG TT  EEE TT   SEE GGGGGGGTT TT  EEE TT    EE GGGGGG TT  EEE TT    :    
ExpBur          :bbeebeebeebbbbbbeeeeeeeeebebbeebeebeebebbbbbbbbbbebeeebbebbbebeebbbbbbbbbebeebebebbeebeebebbbbbebebe:    
Contact         :              b bbbbb                       b b                          b                          

queryA       432:PLVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPH: 531
                :***                          ***********************************************************************:
5wyx_A_1     410:PLVXXXXXXXXXXXXXXXXXXXXXXXXXXFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPH: 509
SecStr          :   --------------------------  TTS SSS  S SS HHHHTTS EEE TTSS SS  TTTTTT    SEEE  SS    B  S TTTTSTT:    
ExpBur          :bee--------------------------eeeeeeebbeeeeebeeebeeeeebbbbbebebeebbeebbeebbebbbbbbbebebebebebebbeebee:    

queryA       532:VKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRY: 631
                :****************************************************************************************************:
5wyx_A_1     510:VKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRY: 609
SecStr          :  EEE  S   B  STTTTTT TT  EEE TT   TT  S   B  GGGGG SS  EEE TT     BSS    EESS  EEE  SS HHHHHT TT TT:    
ExpBur          :bebbbbbebebebeeeebbebbeebebbbbbebeeeeeeeeeebbbebbeebeebeebebbebebeebeeeeebebebbeebbbbbbebbebbebeeeeb:    

queryA       632:ISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGF: 731
                :****************************************************************************************************:
5wyx_A_1     610:ISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGF: 709
SecStr          :TTTTTEETT  EEE  SS  S   HHHHHTS TT SEEE  SS  S   GGGGGG TT  EEE  SS      S GGGT SS  EEE  SS      TTS:    
ExpBur          :bebbeebeebeebbbbebebeebbeebbeebbebbbebbbbebebeebebebbeebeebebbbbeebebeebbebbbebbebbeebbbbebebeebbebb:    

queryA       732:LSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE: 818
                :***************************************************************************************:
5wyx_A_1     710:LSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE: 796
SecStr          :S S     EEE  SS  S   TTTS  SS     EEE TT  EE SSTTHHHHHHHHT TTSB   GGG BEEETTTSTTSBGGG  :    
ExpBur          :bbeeeebebbbbbebebeebeeebeeeeeebebeebbbbebebebeeebeebbebbeebeebebbebbbbebeeeeebeeebbbebe:

Input Residue Numbers for Focused Sites

ex) 2,15,123