Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 S 1 -1 1 0 -1 0 0 0 -1 -3 -3 0 -2 -3 -1 4 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.45 0.00 2 A 4 -2 -2 -2 0 -1 -1 0 -2 -1 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.40 0.00 3 D -2 3 1 5 -4 0 1 -2 -1 -3 -3 1 -2 -3 -2 0 -1 -4 -3 -3 0 37 0 63 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.60 0.00 4 A 3 -2 0 4 -1 -1 0 0 -2 -2 -2 -1 -2 -3 -1 1 0 -3 -2 -1 63 0 0 37 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.35 0.00 5 Q 0 0 0 0 -2 3 2 -1 0 -3 -3 2 -1 -3 -1 3 0 -3 -2 -2 0 0 0 0 0 25 13 0 0 0 0 15 0 0 0 47 0 0 0 0 0.36 0.01 6 S 0 -1 4 0 2 -1 -1 1 0 -3 -3 -1 -2 -3 -2 2 1 -3 -2 -2 6 0 46 0 8 0 0 7 0 0 0 0 0 0 0 28 6 0 0 0 0.38 0.02 7 F -2 -3 -3 -4 -3 -3 -3 -4 0 -1 0 -3 -1 6 -4 -2 -2 1 6 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 56 0 0 0 0 44 0 0.81 0.03 8 L -2 -3 -4 -4 -2 -2 -3 -4 -3 1 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.55 0.03 9 N -2 0 6 1 -3 0 0 -1 0 -4 -4 0 -3 -3 -2 0 0 -4 -2 -3 0 0 94 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0.82 0.04 10 R -2 6 -1 -2 -4 1 0 -3 -1 -3 -3 2 -2 -3 -3 -1 -1 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.91 0.04 11 V 0 -3 -3 -3 -1 -2 -3 -3 -3 2 1 -2 0 -1 -3 -2 0 -3 -2 4 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 93 0.40 0.03 12 C -2 6 -1 -2 3 1 -1 -3 -1 -3 -2 2 -2 -3 -3 -1 -1 -3 -2 -3 0 88 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.75 0.04 13 G 0 -3 -1 -2 -3 -2 -3 6 -2 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.16 0.04 14 V 1 -1 0 -1 -1 -1 -1 -1 -2 1 -1 -1 -1 -2 -1 3 2 -3 -2 1 6 0 0 0 0 0 0 0 0 12 0 0 0 0 0 50 20 0 0 12 0.24 0.02 15 S 1 -1 0 -1 -1 -1 -1 -1 -1 -1 -2 -1 -1 -3 -1 4 1 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88 0 0 0 12 0.42 0.03 16 A 3 -2 1 -1 -1 -1 0 1 -2 0 -1 -1 -1 -2 -2 0 0 -3 -2 1 47 0 12 0 0 0 9 8 0 0 0 0 0 0 0 0 0 0 0 24 0.17 0.02 17 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.51 0.04 18 R -2 6 -1 -2 -4 1 0 -3 -1 -3 -3 2 -2 -3 -3 -1 -1 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.91 0.04 19 L -2 -3 -4 -4 -2 -3 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 12 88 0 0 0 0 0 0 0 0 0 0.49 0.03 20 T -1 -1 -1 0 -2 1 4 -3 -1 1 -1 0 -1 -2 -2 -1 1 -3 -2 2 0 0 0 0 0 0 52 0 0 9 0 0 0 0 0 0 12 0 0 26 0.27 0.02 21 P -1 -3 -2 -2 -3 -2 -2 -3 -3 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.16 0.05 22 C -1 -4 -3 -4 9 -3 -4 -3 -3 -1 1 -3 0 -2 -3 -2 -1 -3 -2 -1 0 0 0 0 77 0 0 0 0 0 23 0 0 0 0 0 0 0 0 0 1.03 0.04 23 G 2 -1 0 -1 -1 -1 -1 2 -1 -1 -1 -1 -1 -2 -1 1 0 -2 -1 -1 37 2 2 2 1 1 2 22 1 2 3 2 1 1 2 14 2 0 1 2 0.20 0.01 24 T 0 -1 4 0 -2 0 0 -1 -1 -3 -3 0 -2 -3 -1 3 2 -3 -2 -2 0 0 35 0 0 0 0 0 0 0 0 0 0 0 0 53 12 0 0 0 0.44 0.03 25 G 0 -3 -1 -2 -3 -2 -3 6 -2 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.16 0.04 26 T -1 -2 -1 -2 3 -2 -2 -3 -2 0 2 -2 1 -1 -2 0 3 -2 -2 1 0 0 0 0 9 0 0 0 0 0 36 0 0 0 0 7 40 0 0 8 0.22 0.02 27 S 0 -1 1 5 -2 1 1 -1 -1 -3 -3 -1 -2 -3 -1 2 1 -4 -3 -2 0 0 0 50 0 8 0 0 0 0 0 0 0 0 0 31 12 0 0 0 0.49 0.02 28 T -1 -2 -1 -2 -2 -1 -1 -2 -2 1 -1 -1 -1 -2 4 0 4 -3 -2 0 0 0 0 0 0 0 0 0 0 14 0 0 0 0 24 0 61 0 0 0 0.50 0.03 29 D -2 -2 1 6 -4 1 1 -2 2 -4 -4 -1 -3 -4 -2 -1 -1 -4 -3 -4 0 0 0 87 0 6 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0.89 0.04 30 V -1 -2 -2 -3 -2 -1 -2 -3 4 2 0 0 0 -1 -3 -2 -1 -2 1 3 0 0 0 0 0 0 0 0 20 8 0 7 0 0 0 0 0 0 7 58 0.21 0.02 31 V -1 -2 -2 -3 4 2 -1 -3 -2 2 0 -2 0 -2 -3 -1 0 -3 -2 3 0 0 0 0 14 19 0 0 0 0 0 0 0 0 0 0 0 0 0 67 0.27 0.03 32 Y -1 -1 -2 -3 -2 -2 -2 -3 -1 0 2 0 0 3 -3 -1 -1 0 4 1 0 0 0 0 0 0 0 0 0 0 26 9 0 18 0 7 0 0 24 14 0.22 0.01 33 R -2 6 -1 -2 -4 1 0 -3 -1 -3 -3 2 -2 -3 -3 -1 -1 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.91 0.04 34 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.51 0.04 35 F -3 -3 -4 -4 -3 -4 -4 -4 -2 2 0 -4 0 7 -4 -3 -2 0 2 0 0 0 0 0 0 0 0 0 0 20 0 0 0 80 0 0 0 0 0 0 0.78 0.07 36 D -2 -2 3 6 -4 -1 1 -2 -1 -4 -4 -1 -3 -4 -2 0 -1 -5 -3 -4 0 0 20 80 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.97 0.07 37 I -1 -3 -4 -4 -2 -3 -4 -4 -4 5 1 -3 1 -1 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 81 0 0 0 0 0 0 0 0 0 19 0.54 0.06 38 Y -2 -3 -3 -4 6 -2 -3 -4 0 -1 1 -3 -1 1 -3 -2 -2 1 6 -1 0 0 0 0 29 0 0 0 0 0 20 0 0 0 0 0 0 0 51 0 0.66 0.07 39 N -2 -1 7 1 -3 0 -1 -1 0 -4 -4 1 -3 -4 -2 0 -1 -4 -3 -3 0 0 91 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0.90 0.09 40 D 1 1 2 0 -2 0 0 -1 -1 -2 -2 3 -2 -1 -2 0 1 -3 -2 -2 20 5 20 4 0 0 4 0 0 0 0 31 0 4 0 0 11 0 0 0 0.22 0.03 41 K -1 0 4 3 -3 0 1 -1 0 -3 -3 2 -2 -4 -2 1 -1 -4 -3 -3 0 0 37 22 0 0 8 0 0 0 0 28 0 0 0 6 0 0 0 0 0.47 0.04 42 V 0 1 -2 -3 -1 -2 -2 -3 -3 2 0 -1 0 -2 -3 0 0 -3 -2 4 6 11 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 75 0.29 0.05 43 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 2 0 -3 -2 -1 88 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0.52 0.07 44 G 0 -3 -1 -2 4 -2 -2 4 -2 -3 -3 -2 -2 1 -2 1 -1 -2 -1 -2 0 0 0 0 16 0 0 52 0 0 0 0 0 12 0 20 0 0 0 0 0.51 0.05 45 F -2 -3 -4 -4 -2 -3 -3 -4 -3 3 3 -3 2 2 -3 -3 -1 -2 0 2 0 0 0 0 0 0 0 0 0 47 31 0 8 14 0 0 0 0 0 0 0.38 0.04 46 A 1 2 -1 -2 -3 -1 -2 5 -2 -3 -3 -1 -2 0 -2 0 -1 -2 -2 -3 9 20 0 0 0 0 0 58 0 0 0 0 0 8 0 5 0 0 0 0 0.53 0.04 47 K -1 1 -1 -1 -3 2 0 -2 -1 -1 1 5 0 -2 -2 -1 -1 -3 -2 -2 0 0 0 0 0 8 0 0 0 0 22 70 0 0 0 0 0 0 0 0 0.38 0.06 48 F -2 -2 1 -2 2 -2 -2 -3 3 0 -1 -2 -1 4 -3 -2 -1 0 4 1 0 0 14 0 6 0 0 0 12 0 0 0 0 24 0 0 0 0 24 20 0.29 0.04 49 L -2 -3 -3 -4 -2 -3 -3 -4 -1 1 3 -3 1 4 -3 -3 -2 0 4 0 0 0 0 0 0 0 0 0 0 0 56 0 0 20 0 0 0 0 24 0 0.46 0.05 50 K -1 2 -1 -1 -4 1 0 -2 -1 -3 -3 6 -2 -4 -2 -1 -1 -4 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.76 0.09 51 T -1 1 0 -2 -2 0 -1 -2 -2 0 -1 2 1 -2 -2 0 2 -3 -2 2 0 8 6 0 0 0 0 0 0 0 0 20 6 0 0 6 27 0 0 27 0.15 0.03 52 N -2 -1 7 1 -3 0 -1 -1 0 -4 -4 -1 -3 -4 -3 0 -1 -4 -3 -4 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.04 0.10 53 C -1 -3 -2 -3 9 -3 -3 -3 -3 -2 -2 -3 -2 -3 -3 0 3 -3 -3 -1 0 0 0 0 67 0 0 0 0 0 0 0 0 0 0 0 33 0 0 0 1.03 0.09 54 C 2 -3 -3 -3 7 -2 -3 -2 -3 0 -1 -2 -1 -2 -2 0 -1 -3 -2 2 28 0 0 0 44 0 0 0 0 0 0 0 0 0 0 5 0 0 0 22 0.56 0.06 55 R -1 6 -1 -2 -3 0 -1 -2 -1 -3 -3 2 -2 -3 -2 1 -1 -3 -2 -3 0 80 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0.73 0.07 56 F -2 -3 -4 -4 -2 -3 -4 -4 -2 2 1 -3 0 6 -4 -3 -2 0 3 0 0 0 0 0 0 0 0 0 0 20 10 0 0 64 0 0 0 0 6 0 0.61 0.06 57 Q -1 1 -1 -1 -3 4 1 -2 -1 -2 -2 2 -1 -3 4 -1 -1 -3 -2 0 0 5 0 0 0 39 0 0 0 0 0 22 0 0 20 0 0 0 0 13 0.46 0.05 58 E -1 2 3 1 -3 1 3 -1 0 -3 -3 1 -2 -3 -2 2 0 -3 -2 -3 0 17 28 0 0 4 31 0 0 0 0 0 0 0 0 20 0 0 0 0 0.41 0.04 59 K 0 -1 -2 1 -2 0 2 -2 -2 1 1 0 0 -1 -2 -1 -1 -3 -2 1 11 0 0 8 0 0 20 0 0 5 26 9 0 0 0 0 0 0 0 21 0.10 0.02 60 D -2 -2 3 6 -4 -1 1 -2 -1 -3 -4 -1 -3 -4 -2 0 0 -5 -3 -3 0 0 20 72 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0.83 0.06 61 E 0 0 0 3 -3 1 3 2 -1 -3 -3 2 -2 -3 -1 0 -1 -3 -2 -3 6 0 0 19 0 0 28 21 0 0 1 22 0 0 0 0 0 0 0 0 0.35 0.03 62 D -1 -1 1 4 -3 1 2 -2 3 -3 -3 0 -2 -3 -2 0 2 -3 -1 -2 0 0 6 35 0 5 13 0 16 0 1 0 0 0 0 0 20 0 0 0 0.39 0.03 63 D -1 -2 0 3 -3 -2 -1 4 -2 1 -2 -2 -2 -2 -2 -1 -1 -3 -3 -1 0 0 0 26 0 0 0 48 0 20 1 0 0 0 0 0 0 0 0 0 0.41 0.04 64 N -1 -1 3 1 -2 0 0 -1 3 -1 -1 -1 3 -1 -1 0 0 -2 -1 -1 2 1 29 8 1 1 2 2 14 1 2 2 21 1 1 2 7 0 1 2 0.17 0.02 65 L -1 1 -1 -2 -2 1 -1 -2 1 0 2 1 1 -1 -1 -1 0 -2 -1 0 2 5 1 1 0 6 1 2 5 1 45 17 0 1 1 2 6 0 1 1 0.10 0.02 66 I -1 0 -2 -2 -2 -1 -1 -2 -2 1 3 2 1 -1 -2 -1 -1 -2 -1 0 2 1 1 1 0 1 1 2 0 5 50 27 0 1 1 2 1 0 1 1 0.15 0.02 67 D -2 -1 1 6 -3 0 1 -1 -1 -3 -3 -1 -2 -3 -1 0 -1 -3 -2 -3 2 1 1 80 0 1 1 2 0 1 2 1 0 1 1 2 1 0 1 1 0.76 0.05 68 S 2 -1 0 -1 -1 1 0 0 -1 -2 -2 1 -1 -3 -1 3 2 -3 -2 -1 22 0 0 0 0 6 0 6 0 0 0 11 0 0 0 36 20 0 0 0 0.28 0.03 69 Y -2 -2 -2 -3 -2 -2 -2 -2 0 -1 -1 -2 -1 5 -2 -2 -2 1 6 -1 2 1 1 1 0 1 1 1 0 1 2 1 0 38 1 1 1 0 43 1 0.57 0.04 70 F -2 -2 -2 -3 -2 -2 -2 -2 -1 -1 0 -2 0 6 -2 -2 -2 4 4 -1 2 1 1 1 0 1 1 1 0 1 2 1 0 59 1 1 1 5 17 1 0.56 0.04 71 V -1 -2 -2 -2 -1 -2 -2 -3 -3 3 1 -2 1 -1 -2 -2 0 -2 -1 4 2 1 1 1 0 1 1 1 0 22 2 1 0 1 1 1 1 0 1 60 0.27 0.03 72 V 0 -2 -2 -2 -1 -2 -2 -3 -3 3 1 -2 0 -1 -2 -1 0 -2 -1 4 2 1 1 1 0 1 1 1 0 12 2 1 0 1 1 1 1 0 1 70 0.28 0.04 73 K -1 2 0 -1 -3 1 0 -1 -1 -2 -2 5 -1 -3 -1 0 -1 -2 -2 -2 2 1 1 1 0 1 1 1 0 1 2 81 0 1 1 1 1 0 1 1 0.48 0.05 74 R -1 5 -1 -1 -3 2 0 -2 0 -3 -2 2 -1 -2 -2 -1 -1 -2 -2 -2 2 68 1 1 0 9 1 1 0 1 2 6 0 1 1 1 1 0 1 1 0.55 0.04 75 H -1 -1 -1 -2 6 -1 -1 -2 5 -2 -2 -1 -1 -2 -2 0 2 -2 0 -1 2 1 1 1 28 1 1 1 28 1 2 1 0 1 1 1 26 0 1 1 0.38 0.04 76 T 0 -1 2 1 -1 -1 -1 -1 -1 0 -1 -1 -1 -2 -1 1 4 -2 -2 0 2 1 12 7 0 1 1 1 0 7 2 1 0 1 1 1 58 0 1 1 0.28 0.04 77 F -1 0 -1 -1 -2 0 0 -2 -1 0 1 2 2 0 2 -1 -1 -2 -1 -1 2 1 1 1 0 1 7 1 0 1 19 29 18 5 9 1 1 0 1 1 0.12 0.02 78 S 0 -1 0 0 -1 0 2 -1 -1 -2 -2 0 -1 -2 -1 3 2 -2 -2 -1 2 1 1 1 0 1 21 1 0 1 2 1 0 1 1 50 13 0 1 1 0.29 0.03 79 N 0 -2 4 -1 -2 -1 -2 2 -1 1 -1 -1 -1 -2 -2 -1 -1 -3 -2 2 5 0 36 0 0 0 0 20 0 6 0 0 0 0 0 0 0 0 0 33 0.23 0.04 80 Y -2 -2 -2 -3 -2 -1 -2 -3 0 -1 0 -2 4 2 -3 -1 2 1 6 -1 0 0 0 0 0 0 0 0 0 0 0 0 28 0 0 0 20 0 52 0 0.52 0.07 81 Q 1 -1 2 2 -3 2 3 -1 -1 -3 -2 0 -2 -3 -2 0 -1 -3 -2 -2 20 0 17 11 0 9 37 0 0 0 6 0 0 0 0 0 0 0 0 0 0.34 0.03 82 H -2 1 0 -2 -3 0 -1 -3 8 -2 0 1 -1 -1 -3 -1 -2 -3 1 -2 0 6 0 0 0 0 0 0 64 0 19 11 0 0 0 0 0 0 0 0 0.62 0.07 83 E -1 -1 -1 1 -4 2 6 -3 -1 -4 -4 0 -3 -4 -2 -1 -1 -4 -3 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.97 0.09 84 E -1 1 0 0 -2 4 2 -2 0 -2 -2 3 1 -2 -1 0 -1 -2 -1 -2 2 1 1 1 0 34 10 1 0 1 2 33 7 1 1 1 1 0 1 1 0.33 0.03 85 T 0 2 0 -1 -1 0 0 -1 1 -1 -2 1 -1 -2 -1 2 2 -2 -1 -1 2 15 1 1 0 1 6 1 5 1 2 7 0 1 1 31 15 0 1 7 0.17 0.02 86 I -1 -3 -3 -4 7 -3 -4 -4 -3 3 0 -3 2 -1 -3 -2 -1 -2 0 1 0 0 0 0 44 0 0 0 0 39 0 0 12 0 0 0 0 0 5 0 0.60 0.06 87 Y -2 -2 -3 -4 -3 -2 -3 -4 1 -2 -2 -3 -2 3 -4 -2 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.28 0.11 88 N -1 0 4 2 -3 3 3 -2 0 -4 -3 0 -2 -4 -2 0 -1 -3 -2 -3 0 0 31 13 0 20 30 0 0 0 0 0 0 0 0 5 0 0 0 0 0.51 0.04 89 L -2 1 -2 1 -2 -1 -1 -3 -2 1 4 0 1 -1 -3 -2 -1 -2 -2 0 0 11 0 13 0 0 0 0 0 0 70 6 0 0 0 0 0 0 0 0 0.27 0.04 90 L -1 -2 -3 -4 -1 -2 -3 -4 -3 2 4 -3 1 0 -3 -2 1 -2 -1 2 0 0 0 0 0 0 0 0 0 5 70 0 0 0 0 0 11 0 0 15 0.38 0.04 91 K 1 2 1 -1 -3 1 1 -1 -1 -3 -3 4 -2 -3 -1 0 -1 -3 -2 -2 20 5 6 0 0 0 5 0 0 0 0 59 0 0 0 5 0 0 0 0 0.38 0.05 92 D -1 0 0 4 -3 0 1 0 -1 -3 -3 2 -2 -1 -2 1 -1 -3 -2 -3 0 0 0 44 0 0 5 6 0 0 0 25 0 6 0 13 0 0 0 0 0.40 0.04 93 C 0 -3 -2 -2 8 -2 -3 2 -3 -2 -2 -2 -2 -3 -2 1 -1 -3 -3 -2 1 0 0 0 61 0 1 21 0 0 1 0 0 0 0 12 0 0 0 1 0.82 0.06 94 P -1 -2 1 2 -3 -1 0 3 -2 -2 0 0 -1 -2 1 -1 -1 -3 -3 -2 0 0 6 13 0 0 8 38 0 0 20 6 0 0 9 0 0 0 0 0 0.27 0.03 95 A 3 -2 -2 -2 -1 -2 -2 -1 -2 0 -1 -2 -1 0 4 0 -1 -3 -1 2 49 0 0 0 0 0 0 0 0 0 0 0 0 6 20 0 0 0 0 24 0.35 0.04 96 V -1 -3 -3 -3 -1 -3 -3 -4 -3 2 1 -3 0 -1 -3 -2 1 -3 -2 4 0 0 0 0 0 0 0 0 0 5 6 0 0 0 0 0 8 0 0 81 0.42 0.06 97 A 4 -2 -2 -3 -1 -1 -2 -1 -2 -1 1 -1 0 -2 -2 0 -1 -3 -2 0 80 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0.38 0.06 98 K -1 1 -1 1 -3 3 3 -2 -1 -1 -2 2 -1 -3 1 -1 -1 -3 -2 -1 0 6 0 8 0 20 33 0 0 4 0 15 0 0 5 0 0 0 0 9 0.34 0.03 99 H -2 -1 0 -2 -4 0 -1 -3 9 -4 -4 -1 -2 -2 -3 -2 -2 -3 1 -4 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 1.38 0.12 100 D 1 -2 1 6 -3 -1 1 -1 -2 -3 -4 -1 -3 -4 -2 0 -1 -4 -3 -3 20 0 0 75 0 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0.76 0.06 101 F -2 -2 -2 -3 -2 -2 -2 -3 -1 0 0 -2 0 7 -3 -2 -2 1 2 -1 2 1 1 1 0 1 1 1 0 1 2 1 0 81 1 1 1 0 1 1 0.66 0.05 102 F -2 -2 -2 -3 -2 -2 -2 -3 -1 0 0 -2 0 7 -3 -2 -2 1 2 -1 2 1 1 1 0 1 1 1 0 1 2 1 0 81 1 1 1 0 1 1 0.66 0.05 103 K 0 -1 -1 -1 -1 -1 -1 -2 -2 1 -1 1 0 -2 -1 0 3 -2 -1 1 2 1 1 1 0 1 1 1 0 14 2 15 0 1 1 1 46 0 1 9 0.17 0.03 104 F -2 -2 -2 -3 -2 -2 -2 -2 -1 -1 0 -2 -1 5 -3 -2 -2 7 3 -1 2 1 1 1 0 1 1 1 0 1 2 1 0 53 1 1 1 22 6 1 0.71 0.05 105 R -2 3 2 3 -4 0 0 -2 2 -3 -3 2 -2 -3 -2 -1 -1 -4 -2 -3 0 29 14 30 0 0 0 0 6 0 0 22 0 0 0 0 0 0 0 0 0.46 0.04 106 I -1 -1 -2 0 -2 -1 1 -3 -2 2 0 0 0 3 -2 -1 -1 -2 0 2 0 0 0 5 0 0 17 0 0 16 1 8 0 20 0 0 0 0 0 29 0.11 0.02 107 D -1 -1 4 4 -3 0 2 2 -1 -4 -4 -1 -3 -4 -2 0 -1 -4 -3 -3 0 0 28 33 0 0 17 22 0 0 0 0 0 0 0 0 0 0 0 0 0.54 0.04 108 G -1 3 0 -1 -3 0 -1 3 4 -3 -3 1 -2 -3 -2 -1 -1 -3 -1 -3 1 22 0 0 0 0 1 38 20 0 1 14 0 0 0 1 0 0 0 1 0.40 0.03 109 D 0 0 0 3 2 -1 0 -1 -1 -1 -2 -1 -1 -2 -1 2 1 -3 -2 0 6 6 0 29 6 0 1 1 0 0 1 0 0 0 0 22 11 0 0 15 0.19 0.02 110 M -1 2 -1 -2 -2 0 0 2 -1 1 0 1 2 -2 -2 -1 -1 -2 -2 1 1 17 0 0 0 0 6 21 0 11 1 14 14 0 0 1 0 0 0 12 0.11 0.02 111 V -1 -2 -2 -3 -1 -2 -2 -3 -1 2 0 -2 0 1 -2 0 3 -1 3 2 0 0 0 0 0 0 0 0 0 14 0 0 0 5 0 0 39 0 16 25 0.24 0.04 112 P -1 -2 -1 2 -3 -2 -1 3 -2 -3 -3 -1 -3 -2 6 -1 -2 -3 1 -3 0 0 0 20 0 0 0 28 0 0 0 0 0 0 44 0 0 0 8 0 0.85 0.05 113 H -2 -1 4 -1 -3 0 -1 -2 7 -3 -3 -1 -2 0 -3 -1 -1 -1 4 -3 0 0 36 0 0 0 0 0 44 0 0 0 0 0 0 0 0 0 20 0 0.68 0.07 114 I -1 -3 -4 -4 -1 -3 -3 -4 -4 4 2 -3 1 0 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 47 20 0 0 0 0 0 0 0 0 33 0.41 0.04 115 S 1 -2 -1 -2 3 -2 -2 -2 -2 2 0 -2 0 -2 -2 2 0 -3 -2 2 5 0 0 0 10 0 0 0 0 20 0 0 0 0 0 34 0 0 0 30 0.20 0.04 116 R -2 7 -1 -2 -4 1 -1 -3 -1 -4 -3 2 -2 -3 -3 -1 -2 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.03 0.09 117 Q -1 2 -1 -1 -3 4 1 -2 2 -3 -2 2 -1 -1 -2 -1 -1 -1 3 -2 0 11 0 0 0 41 6 0 6 0 0 17 0 0 0 0 0 0 20 0 0.42 0.05 118 R -2 3 2 3 -3 0 0 -2 0 -3 -3 0 -2 -1 -2 0 -1 -1 3 -3 0 31 17 27 0 0 0 0 0 0 0 0 0 0 0 4 0 0 20 0 0.38 0.04 119 L -1 -2 -3 -3 -2 -2 -3 -4 -3 1 4 -2 1 0 -3 -2 2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 80 0 0 0 0 0 20 0 0 0 0.42 0.05 120 T 0 -2 0 -1 -1 -1 -1 -2 -2 -1 -2 -1 -1 -3 -2 2 5 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 89 0 0 0 0.64 0.08 121 K -1 1 -1 0 -4 1 3 -2 -1 -3 -3 4 -2 -4 4 -1 -1 -4 -3 -3 0 0 0 0 0 0 24 0 0 0 0 56 0 0 20 0 0 0 0 0 0.60 0.05 122 Y -2 -2 -3 -4 -3 -2 -3 -4 1 -2 -2 -3 -2 3 -4 -2 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.28 0.11 123 T 0 -2 0 -1 -1 -1 -1 -2 -2 -1 -2 -1 -1 -3 -1 2 5 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 80 0 0 0 0.58 0.07 124 M -2 -2 -3 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0 0 0 0 0 0 0 70 0 0.64 0.05 868 P -1 -3 -3 -2 -2 -2 -2 -3 -3 0 -2 -2 -1 -3 7 -1 -1 -4 -3 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70 0 0 0 0 30 1.29 0.05 869 L -2 -2 -3 -4 -2 -2 -3 -4 -1 1 4 -3 1 1 -3 -3 -2 0 4 0 0 0 0 0 0 0 0 0 0 0 70 0 0 0 0 0 0 0 30 0 0.45 0.04 870 T 0 -1 0 -1 -1 -1 -1 -1 -2 0 -1 -1 -1 -2 -1 3 3 -3 -2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 31 0 0 19 0.31 0.03 871 K -1 4 0 -1 -3 1 0 -2 3 -3 -3 4 -2 -2 -2 -1 -1 -2 1 -3 0 30 0 0 0 0 0 0 10 0 0 51 0 0 0 0 0 0 8 0 0.46 0.03 872 H -2 -1 0 -2 -3 0 -1 -3 8 -3 -3 -1 -2 0 -3 -2 -2 -1 5 -3 0 0 0 0 0 0 0 0 70 0 0 0 0 0 0 0 0 0 30 0 0.91 0.06 873 P -1 0 0 2 -4 3 3 -2 -1 -3 -3 0 -2 -4 5 -1 -1 -3 -3 -3 0 0 0 13 0 30 28 0 0 0 0 0 0 0 29 0 0 0 0 0 0.69 0.03 874 N -2 -1 4 3 -3 0 0 -1 -1 -3 -4 1 -3 -4 5 0 -1 -4 -3 -3 0 0 42 18 0 0 0 0 0 0 0 11 0 0 30 0 0 0 0 0 0.68 0.03 875 Q -1 -1 -1 0 -3 2 4 -2 -1 -2 -3 0 -2 -3 5 0 0 -3 -3 -2 0 0 0 0 0 9 45 0 0 4 0 0 0 0 34 5 4 0 0 0 0.69 0.03 876 E -1 -1 -1 0 -3 1 4 -3 -1 -2 -2 0 -1 3 -2 -1 -1 -1 0 -2 5 0 0 0 0 0 65 0 0 0 0 0 0 30 0 0 0 0 0 0 0.45 0.04 877 Y -2 -2 -3 -4 -3 -2 -3 -4 1 -1 -1 -3 -1 5 -4 -2 -2 2 7 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 30 0 0 0 0 70 0 0.91 0.05 878 A 0 2 3 0 -3 4 1 -1 0 -3 -3 2 -1 -3 -2 0 -1 -3 -2 -3 9 15 30 0 0 36 0 0 0 0 0 11 0 0 0 0 0 0 0 0 0.41 0.03 879 D -1 1 3 1 -3 0 0 3 -1 -4 -3 3 -2 -3 -2 0 -1 -3 -3 -3 0 5 22 9 0 0 0 30 0 0 0 35 0 0 0 0 0 0 0 0 0.39 0.02 880 V -1 -3 -3 -4 -1 -3 -3 -4 -3 2 2 -3 1 -1 -3 -2 -1 -3 -1 4 0 0 0 0 0 0 0 0 0 0 30 0 0 0 0 0 0 0 0 70 0.38 0.03 881 F -3 -3 -4 -4 -3 -4 -4 -4 -2 -1 0 -4 0 7 -4 -3 -3 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.98 0.06 882 H -2 2 -1 -2 -3 3 0 -3 2 -2 -2 0 -1 1 -3 -1 -1 6 4 -2 0 13 0 0 0 30 0 0 9 0 0 0 0 6 0 0 5 18 20 0 0.48 0.03 883 L 0 -3 -3 -3 2 -2 -3 -3 -3 2 1 -2 0 -1 -3 -1 0 -3 -2 4 5 0 0 0 5 0 0 0 0 0 9 0 0 0 0 0 5 0 0 76 0.32 0.03 884 Y -2 -2 -3 -4 -2 -2 -3 -4 0 0 2 -3 1 4 -3 -2 -2 1 5 -1 0 0 0 0 0 0 0 0 0 0 26 0 5 30 0 0 0 0 39 0 0.53 0.03 885 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.57 0.04 886 Q 0 -1 1 5 -3 3 2 -2 -1 -3 -3 0 -2 -4 -2 0 -1 -4 -3 -3 10 0 0 55 0 26 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0.59 0.03 887 Y -2 0 -2 -3 -3 -1 -1 -3 0 -2 -2 2 -2 1 -3 -2 -2 8 5 -2 0 0 0 0 0 0 0 0 0 0 0 30 0 0 0 0 0 25 45 0 0.77 0.05 888 I -1 -3 -3 -4 -1 -3 -3 -4 -4 4 1 -3 1 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 45 0 0 0 0 0 0 0 0 0 55 0.43 0.03 889 R -1 3 0 0 -4 4 2 -2 0 -3 -3 4 -1 -3 -2 0 -1 -3 -2 -3 0 15 0 0 0 30 12 0 0 0 0 43 0 0 0 0 0 0 0 0 0.51 0.03 890 K -1 1 0 -1 -3 4 1 -2 5 -3 -3 4 -1 -3 -2 -1 -1 -3 -1 -3 0 0 0 0 0 30 0 0 25 0 0 45 0 0 0 0 0 0 0 0 0.50 0.04 891 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 4 -3 1 4 -3 -3 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 70 0 0 30 0 0 0 0 0 0 0.47 0.03 892 H -2 3 1 -2 -3 1 -1 -3 4 -3 -2 0 -2 1 -3 -1 -1 0 5 -2 0 30 10 0 0 5 0 0 14 0 0 0 0 0 0 0 0 0 41 0 0.45 0.03 893 D -1 1 2 1 -3 2 1 -2 -1 -3 -3 4 -2 -4 -1 0 -1 -3 -2 -3 0 0 13 9 0 6 5 0 0 0 0 67 0 0 0 0 0 0 0 0 0.47 0.03 894 E -2 -1 2 5 -3 0 3 -2 -1 -3 -3 0 -3 -4 -2 0 1 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-2 -3 0 -2 -3 -1 2 2 -3 -2 -2 8 0 0 0 0 7 14 28 0 0 0 0 0 0 0 17 25 0 0 0 0.30 0.01 913 S 2 -1 0 2 -1 1 0 -1 -1 -2 -1 0 -1 -3 -1 2 0 -3 -2 -1 30 0 0 15 0 13 0 0 0 0 6 0 0 0 0 36 0 0 0 0 0.25 0.02 914 R -1 3 0 -1 -4 1 1 -2 -1 -3 -3 5 -2 -4 -1 -1 -1 -3 -2 -3 0 12 0 0 0 0 0 0 0 0 0 88 0 0 0 0 0 0 0 0 0.61 0.03 915 Y -3 -3 -3 -4 -3 -3 -3 -4 -1 -1 0 -3 0 7 -4 -3 -2 1 5 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 80 0 0 0 0 20 0 0.84 0.04 916 W -2 -3 -3 -4 -2 -2 -3 -3 -3 -3 -2 -3 -2 0 -4 -2 1 11 2 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 81 0 0 1.96 0.06 917 E -1 -1 0 4 2 1 4 -2 -1 -3 -3 0 -3 -4 -2 0 -1 -4 -3 -3 0 0 0 33 7 0 53 0 0 0 0 0 0 0 0 7 0 0 0 0 0.57 0.02 918 P -1 0 -1 1 -4 2 5 -2 -1 -2 -3 0 -2 -3 2 -1 -1 -3 -2 -1 0 0 0 0 0 9 71 0 0 0 0 0 0 0 12 0 0 0 0 8 0.59 0.03 919 E 1 -1 0 1 -2 1 3 0 -1 -3 -3 0 -2 -3 -1 3 1 -3 -2 -2 6 0 0 7 0 0 36 6 0 0 0 0 0 0 0 39 6 0 0 0 0.36 0.02 920 F -3 -3 -4 -4 -3 -4 -4 -4 -2 0 0 -4 0 7 -4 -3 -3 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.94 0.04 921 Y -2 -2 -3 -4 -3 -2 -2 -4 2 -2 -1 -2 -1 3 -3 -2 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.10 0.05 922 E 2 2 -1 0 -2 1 3 -1 -1 -3 -2 2 -2 -3 -1 0 -1 -3 -2 -2 35 17 0 0 0 0 29 0 0 0 0 19 0 0 0 0 0 0 0 0 0.31 0.02 923 A 1 -1 4 3 -2 0 0 -1 0 -3 -3 0 -2 -3 -2 2 0 -4 -2 -2 12 0 42 17 0 0 0 0 0 0 0 0 0 0 0 28 0 0 0 0 0.43 0.02 924 M -1 -2 -3 -4 -2 -1 -3 -3 -2 1 3 -2 6 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 25 0 75 0 0 0 0 0 0 0 0.49 0.04 925 Y -2 -2 -3 -4 -3 -2 -2 -4 2 -2 -1 -2 -1 3 -3 -2 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.10 0.05 926 T -1 1 -1 0 -2 0 3 -2 -1 -1 1 0 1 -2 -2 1 1 -3 -2 -1 0 9 0 0 0 0 35 0 0 0 19 0 8 0 0 12 18 0 0 0 0.18 0.01 927 P 1 2 1 -1 -2 1 1 -1 -1 -3 -3 2 -2 -3 2 1 0 -3 -2 -2 15 13 7 0 0 7 8 0 0 0 0 27 0 0 12 12 0 0 0 0 0.31 0.01 928 H 0 -1 0 -1 -2 0 -1 -1 3 -3 -3 -1 -2 -3 4 3 0 -3 -1 -2 0 0 0 0 0 0 0 0 12 0 0 0 0 0 27 61 0 0 0 0 0.58 0.03 929 T 2 -1 -1 -1 -1 -1 -1 -1 -2 -1 -2 -1 -1 -2 -1 2 4 -3 -2 0 33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 61 0 0 0 0.38 0.03 930 V 0 -2 -2 -3 -1 -2 -2 -3 -3 2 0 -2 0 -1 -2 0 3 -3 -2 3 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 34 0 0 58 0.29 0.02 931 L -2 -2 -4 -4 -2 -2 -3 -4 -3 1 4 -3 4 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 81 0 19 0 0 0 0 0 0 0 0.48 0.03 932 Q -1 1 0 -1 -3 6 2 -2 0 -3 -3 1 -1 -4 -2 0 -1 -2 -2 -3 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.84 0.05 K Lambda Standard Ungapped 0.1374 0.3236 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1374 0.3236 PSI Gapped 0.0410 0.2670