Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 S 3 -1 0 -1 -1 -1 -1 -1 -2 -3 -3 -1 -2 -3 -1 4 1 -3 -2 -2 33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67 0 0 0 0 0.51 0.07 2 G 0 -3 -1 -2 -3 -2 -3 6 -3 -5 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.31 0.09 3 F -2 -3 -4 -4 -2 -3 -4 -4 -3 2 4 -3 1 4 -4 -3 -2 -1 0 1 0 0 0 0 0 0 0 0 0 16 58 0 0 26 0 0 0 0 0 0 0.46 0.05 4 R -1 4 -1 -2 -3 0 -1 -3 -2 0 -1 2 -1 -2 -2 -1 0 -3 -2 2 0 39 0 0 0 0 0 0 0 0 0 21 0 0 0 0 8 0 0 32 0.32 0.05 5 K -1 3 -1 -1 -4 1 0 -2 -1 -3 -3 6 -2 -4 -2 -1 -1 -4 -2 -3 0 8 0 0 0 0 0 0 0 0 0 92 0 0 0 0 0 0 0 0 0.78 0.09 6 M -2 -2 -3 -4 -2 -1 -3 -4 -2 1 2 -2 8 -1 -3 -2 -1 -2 -2 0 0 0 0 0 0 0 0 0 0 0 15 0 85 0 0 0 0 0 0 0 0.79 0.11 7 A 4 -2 -2 -2 -1 -2 -2 -1 -2 0 -1 -1 -1 -2 -2 1 0 -3 -2 2 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 31 0.32 0.06 8 F 0 0 1 -1 -2 4 0 -2 3 -2 -2 0 -1 2 -2 2 -1 -2 0 -2 10 0 6 0 0 35 0 0 13 0 0 0 0 16 0 20 0 0 0 0 0.28 0.05 9 P -2 -3 -3 -2 -4 -2 -2 -3 -3 -4 -4 -2 -3 -5 8 -2 -2 -5 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.31 0.12 10 S 1 -1 0 -1 -1 -1 -1 -1 -2 -3 -3 -1 -2 -3 -1 5 3 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 84 16 0 0 0 0.61 0.08 11 G 0 -2 0 -1 -2 -2 -2 5 -2 -4 -4 -2 -3 -4 -2 2 -1 -3 -3 -3 0 0 0 0 0 0 0 69 0 0 0 0 0 0 0 31 0 0 0 0 0.82 0.07 12 K 1 0 -2 0 2 -1 -1 -2 -2 1 1 2 0 0 -2 -1 -1 -3 -1 1 20 0 0 5 6 0 0 0 0 6 13 27 0 6 0 0 0 0 0 16 0.07 0.03 13 V -1 -3 -4 -4 -1 -3 -3 -4 -4 3 0 -3 0 -1 -3 -2 -1 -4 -2 5 0 0 0 0 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 95 0.60 0.08 14 E -2 -1 -1 1 -5 1 6 -3 -1 -4 -4 0 -3 -4 -2 -1 -2 -4 -3 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 1.04 0.10 15 G 0 1 1 -1 -3 0 -1 2 -2 -3 -3 2 -2 -4 5 -1 -1 -4 -3 -3 5 6 10 0 0 0 0 17 0 0 0 27 0 0 35 0 0 0 0 0 0.62 0.05 16 C -1 -4 -4 -5 10 -4 -5 -3 -4 -2 -2 -4 -2 -3 -4 -2 -2 -3 -3 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.92 0.14 17 M -1 -3 -3 -4 -2 -2 -3 -4 -3 4 2 -3 4 0 -3 -2 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 43 13 0 21 0 0 0 0 0 0 23 0.40 0.05 18 V -1 -3 -4 -4 -1 -3 -3 -4 -4 2 0 -3 0 -1 -3 -2 -1 -4 -2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.63 0.09 19 Q -1 4 0 -1 -3 3 0 -2 -1 -3 -3 2 -2 -3 -2 2 0 -3 -2 -3 0 35 0 0 0 26 0 0 0 0 0 8 0 0 0 31 0 0 0 0 0.47 0.06 20 V -1 -3 -4 -4 -1 -3 -3 -4 -4 2 0 -3 0 -1 -3 -2 -1 -4 -2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.63 0.09 21 T 0 -2 1 -1 5 -1 -1 -2 -2 -2 -2 -1 -2 -3 -2 2 4 -3 -2 -1 5 0 8 0 18 0 0 0 0 0 0 0 0 0 0 26 42 0 0 0 0.42 0.06 22 C -2 -3 -3 -4 6 -2 -3 -4 1 -2 -2 -3 -2 2 -4 -2 -2 1 7 -2 0 0 0 0 26 0 0 0 0 0 0 0 0 0 0 0 0 0 74 0 1.06 0.10 23 G 0 1 -1 -2 -3 -2 -2 6 -2 -4 -4 -1 -3 -4 -3 -1 -2 -3 -3 -4 0 15 0 0 0 0 0 85 0 0 0 0 0 0 0 0 0 0 0 0 1.01 0.08 24 T 0 -1 4 0 -2 -1 -1 2 -1 -3 -3 -1 -2 -3 -2 3 1 -4 -3 -3 0 0 39 0 0 0 0 15 0 0 0 0 0 0 0 35 11 0 0 0 0.46 0.05 25 T -1 -2 3 -1 -2 -1 -2 -2 -1 0 1 -1 5 -1 -3 0 2 -3 -2 0 0 0 26 0 0 0 0 0 0 0 6 0 45 0 0 0 23 0 0 0 0.34 0.07 26 T 0 -2 2 -1 -1 -1 -2 -2 -2 0 -1 -1 -1 -2 -2 0 4 -3 -2 2 6 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 56 0 0 23 0.35 0.06 27 L -2 -3 -4 -4 -2 -3 -4 -4 -3 1 5 -3 2 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.68 0.08 28 N -2 -1 7 1 -4 -1 -1 -1 0 -4 -4 -1 -3 -4 -3 0 -1 -5 -3 -4 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.11 29 G 0 -3 -1 -2 -3 -2 -3 6 -3 -5 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.31 0.09 30 L -2 -3 -4 -4 -2 -3 -3 -4 -3 2 4 -3 2 0 -3 -3 -2 -2 -2 1 0 0 0 0 0 0 0 0 0 8 86 0 0 0 0 0 0 0 0 6 0.57 0.06 31 W -4 -4 -5 -5 -3 -3 -4 -4 -3 -4 -3 -4 -2 0 -5 -4 -4 12 1 -4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 3.05 0.16 32 L -2 -3 -4 -4 -2 -3 -4 -4 -3 1 5 -3 2 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.68 0.08 33 D -1 -3 0 5 -4 -1 0 4 -2 -4 -4 -2 -4 -4 -2 -1 -2 -4 -4 -4 0 0 0 50 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0.82 0.07 34 D -2 -2 4 6 -4 -1 1 -2 -1 -4 -4 -1 -4 -4 -2 -1 -1 -5 -4 -4 0 0 23 77 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.99 0.08 35 V -1 -1 -1 -1 -2 0 1 -2 -1 1 -1 1 -1 1 -2 1 3 -2 1 0 0 0 0 0 0 0 11 0 0 12 0 16 0 8 0 8 35 0 5 5 0.15 0.03 36 V -1 -3 -4 -4 -1 -3 -3 -4 -4 3 1 -3 0 -1 -3 -2 -1 -3 -2 5 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 85 0.56 0.08 37 Y -2 -3 -3 -4 -2 -2 -3 -4 0 2 0 -3 1 2 -3 -2 0 6 6 0 0 0 0 0 0 0 0 0 0 25 0 0 6 0 0 0 6 16 48 0 0.66 0.07 38 C -1 -4 -4 -5 10 -4 -5 -3 -4 -2 -2 -4 -2 -3 -4 -2 -2 -3 -3 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.92 0.14 39 P -2 -3 -3 -2 -4 -2 -2 -3 -3 -4 -4 -2 -3 -5 8 -2 -2 -5 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.31 0.12 40 R -2 7 -1 -2 -4 0 -1 -3 -1 -4 -3 2 -2 -4 -3 -1 -2 -4 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.11 0.10 41 H -3 -1 0 -2 -4 0 -1 -3 9 -4 -4 -2 -2 -2 -3 -2 -3 -3 1 -4 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 1.52 0.13 42 V -1 -3 -4 -4 -1 -3 -3 -4 -4 3 0 -3 0 -1 -3 -2 -1 -4 -2 5 0 0 0 0 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 95 0.60 0.08 43 I -2 -3 -4 -4 -2 -3 -3 -4 -3 4 2 -3 4 0 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 62 15 0 23 0 0 0 0 0 0 0 0.48 0.07 44 C 2 -2 -2 -3 8 -2 -2 0 -2 -2 -2 -2 -2 -2 -2 0 -1 -2 -2 -1 30 1 1 1 51 1 1 8 0 1 1 1 0 0 1 1 1 0 0 1 0.67 0.06 45 T 1 -1 0 -1 -2 -1 -1 -1 -2 -2 -1 0 -1 -3 4 3 1 -3 -2 -2 6 0 0 0 0 0 0 1 0 0 6 8 0 0 22 43 11 0 0 0 0.40 0.04 46 S 2 1 0 0 -1 0 0 -1 -1 -2 -2 0 -1 -3 -1 3 2 -3 -2 -1 27 8 0 6 0 0 0 1 0 0 1 0 0 0 0 41 13 0 0 0 0.28 0.04 47 E 0 -2 0 3 -2 0 1 2 -2 -3 -3 -1 -2 -3 -2 1 3 -3 -3 -2 5 0 0 29 0 0 11 15 0 0 0 0 0 0 0 11 29 0 0 0 0.35 0.04 48 D -1 0 2 3 -3 2 2 -1 -1 -3 -3 1 -2 -3 -2 1 1 -4 -2 -2 0 0 12 29 0 16 8 0 0 0 0 8 0 0 0 17 11 0 0 0 0.38 0.04 49 M 0 0 -2 -3 -2 0 -2 -3 -2 1 2 -1 4 1 -3 -1 1 -2 -1 1 6 5 0 0 0 7 0 0 0 0 23 0 27 8 0 0 11 0 0 12 0.17 0.04 50 L 0 0 0 -2 -1 -1 -2 -2 -2 1 1 -1 0 -1 -2 1 2 4 -1 1 8 5 5 0 0 0 0 0 0 18 17 0 0 0 0 18 16 7 0 5 0.13 0.02 51 N -1 -1 4 4 -3 0 1 1 -1 -2 -3 -1 -2 -3 -2 0 -1 -3 -2 -1 1 1 32 39 0 0 6 8 0 1 1 1 0 0 1 1 1 0 0 6 0.46 0.04 52 P -1 -2 -2 0 -3 -2 -1 -3 -1 1 -2 -2 -2 -1 6 -1 -1 -2 3 -1 1 0 0 8 0 0 0 1 0 17 1 0 0 0 51 1 0 0 18 0 0.83 0.06 53 N -2 -1 4 5 -3 1 1 -1 -1 -3 -4 -1 -3 -3 -2 0 -1 -4 -3 -3 1 0 37 48 0 8 0 1 0 0 1 0 0 0 0 1 0 0 0 0 0.68 0.06 54 Y -2 -2 -2 -3 -3 -2 -2 -3 4 -2 -2 -2 -2 2 -3 -2 -2 5 7 -2 1 0 0 0 0 0 0 1 12 0 1 0 0 0 0 1 0 8 73 0 0.96 0.09 55 E 1 -1 0 3 -2 0 3 0 -1 -3 -3 0 -2 -3 2 1 0 -3 -2 -2 12 0 0 22 0 0 28 8 0 0 1 0 0 0 8 11 6 0 0 0 0.33 0.03 56 D 1 0 3 3 -2 -1 0 -1 2 -2 -1 -1 0 -2 -2 0 -1 -3 1 -2 21 8 22 26 0 0 0 0 6 0 6 0 6 0 0 0 0 0 6 0 0.21 0.03 57 L 0 -2 -2 -2 -2 -1 0 -3 -2 1 3 -2 1 -1 -2 1 -1 -3 -2 1 6 0 0 0 0 0 11 0 0 0 50 0 0 0 0 18 0 0 0 15 0.18 0.04 58 L -1 -2 -3 -4 -2 -2 -3 -4 -2 2 4 -3 2 0 -3 -1 -1 -2 1 1 0 0 0 0 0 0 0 0 0 6 69 0 5 0 0 8 0 0 6 6 0.37 0.05 59 I -1 -2 2 -2 4 -2 -2 -2 -2 2 1 -2 2 -1 -3 1 0 -3 -2 1 0 0 15 0 16 0 0 0 0 21 6 0 14 0 0 17 0 0 0 11 0.18 0.04 60 R -1 5 -1 -2 -3 0 -1 -2 -1 -2 0 1 -1 -2 -2 2 0 -3 -2 -2 0 53 0 0 0 0 0 0 0 0 15 0 0 0 0 26 6 0 0 0 0.39 0.06 61 K 1 -1 -2 -3 -2 -1 -1 -2 -2 1 1 1 2 -1 -2 -1 -1 -3 -2 2 23 0 0 0 0 0 0 0 0 0 18 21 11 0 0 0 0 0 0 27 0.14 0.03 62 S 0 2 2 -1 -1 0 -1 -1 -1 -1 -1 0 -1 -2 -1 1 2 -2 -2 -1 9 18 16 1 0 1 1 1 0 6 2 1 0 1 1 12 28 0 1 1 0.18 0.02 63 N -1 -1 5 0 -2 -1 -1 -1 0 -1 1 -1 -1 -2 -2 1 0 -2 -2 -1 1 1 50 1 0 1 1 1 0 1 24 1 0 1 1 12 1 0 1 1 0.29 0.04 64 H -2 -1 0 -2 -3 0 -1 -1 8 -3 -2 -1 -2 -1 -3 0 -2 -2 2 -3 0 0 0 0 0 0 0 5 71 0 5 0 0 0 0 11 0 0 8 0 0.82 0.09 65 N -1 -1 4 3 -3 0 2 -1 0 -4 -4 0 -3 -4 -2 2 0 -4 -3 -3 0 0 40 24 0 0 15 0 0 0 0 0 0 0 0 21 0 0 0 0 0.55 0.05 66 F -3 -4 -4 -4 -3 -4 -4 -4 -2 -1 0 -4 -1 8 -5 -3 -3 0 3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 1.20 0.11 67 L 0 -1 0 -1 2 0 1 -2 2 0 0 -1 -1 -2 -2 3 1 -3 -2 -1 0 0 0 0 5 0 15 0 8 10 11 0 0 0 0 40 11 0 0 0 0.17 0.04 68 V -1 -3 -4 -4 -1 -3 -3 -4 -4 4 1 -3 1 -1 -3 -2 -1 -3 -2 5 0 0 0 0 0 0 0 0 0 29 0 0 0 0 0 0 0 0 0 71 0.52 0.07 69 Q 0 -1 -1 -1 -2 3 0 -2 -1 0 0 0 2 -2 -2 2 1 -3 -2 0 5 0 0 0 0 26 0 0 0 6 6 0 11 0 0 31 7 0 0 8 0.18 0.04 70 A 1 -1 0 -1 -2 1 0 2 1 -2 -2 1 -2 0 -2 2 2 -3 -1 -2 11 0 0 0 0 8 0 16 6 0 0 11 0 6 0 28 15 0 0 0 0.21 0.03 71 G 1 -1 3 1 -3 2 -1 4 -1 -3 -3 -1 -2 -3 -2 0 -1 -3 -3 -3 16 0 25 6 0 15 0 39 0 0 0 0 0 0 0 0 0 0 0 0 0.45 0.04 72 N -1 2 4 0 -3 1 -1 1 2 -3 -3 0 -2 -3 2 0 0 -4 -2 -3 0 16 41 0 0 5 0 14 7 0 0 0 0 0 10 0 6 0 0 0 0.41 0.05 73 V 2 -2 -2 -3 -1 -2 -2 -2 2 1 1 -2 3 -1 -2 -1 -1 -3 -1 3 27 0 0 0 0 0 0 0 8 0 6 0 17 0 0 0 0 0 0 43 0.21 0.05 74 Q -1 -1 3 -1 -2 1 -1 -2 -1 -2 -1 -1 -1 4 -2 1 1 -1 1 -2 0 0 23 0 0 11 0 0 0 0 0 0 0 35 0 16 15 0 0 0 0.27 0.05 75 L -2 -3 -4 -4 -2 -3 -4 -4 -3 2 5 -3 2 0 -4 -3 -2 -2 -2 1 0 0 0 0 0 0 0 0 0 8 92 0 0 0 0 0 0 0 0 0 0.62 0.07 76 R -1 3 2 -1 -3 0 -1 3 -1 -3 -3 0 -2 -3 -2 0 1 -3 -3 -3 0 34 15 0 0 0 0 35 0 0 0 0 0 0 0 0 16 0 0 0 0.43 0.05 77 V -1 -3 -4 -4 -1 -3 -3 -4 -4 2 0 -3 0 -1 -3 -2 -1 -4 -2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.63 0.09 78 I -1 -3 -3 -4 -1 -3 -3 -4 -4 3 1 -3 2 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 25 0 0 11 0 0 0 0 0 0 65 0.46 0.06 79 G 1 -2 0 -1 -2 -1 -1 4 -2 -3 -3 -1 -2 -3 -2 4 0 -3 -3 -3 5 0 0 0 0 0 0 41 0 0 0 0 0 0 0 54 0 0 0 0 0.58 0.06 80 H 2 2 -1 -2 -2 0 -1 -2 6 -2 -2 -1 -1 -1 -2 -1 -1 -1 3 -1 29 15 0 0 0 0 0 0 34 0 0 0 0 0 0 0 0 0 16 6 0.36 0.06 81 S 0 3 0 -1 -2 2 0 -2 -1 -2 -2 1 -1 -3 -2 2 3 -3 -2 -2 5 20 0 0 0 16 0 0 0 0 0 5 0 0 0 22 31 0 0 0 0.33 0.04 82 M -2 -2 -3 -4 -2 -1 -3 -4 -2 1 2 -2 7 0 -3 -2 -1 -1 2 0 0 0 0 0 0 0 0 0 0 0 15 0 74 0 0 0 0 0 11 0 0.64 0.10 83 Q -1 3 -1 -1 -3 3 1 -2 3 -2 -2 3 -1 -3 -2 -1 -1 -3 -1 -1 0 17 0 0 0 26 8 0 12 0 0 26 0 0 0 0 0 0 0 10 0.37 0.04 84 N 0 -3 2 -1 -3 -2 -2 6 -2 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 11 0 0 0 0 89 0 0 0 0 0 0 0 0 0 0 0 0 1.11 0.08 85 C 2 -2 -1 -2 5 -2 -2 -2 -2 0 -1 -2 -1 -2 -2 2 2 -3 -2 1 20 0 0 0 22 0 0 0 0 0 0 0 0 0 0 19 17 0 0 22 0.30 0.04 86 V -1 -2 1 -2 -2 0 -2 -3 -2 1 3 -2 2 -1 -3 -2 0 -3 -2 2 0 0 11 0 0 5 0 0 0 0 46 0 6 0 0 0 6 0 0 26 0.22 0.04 87 L -2 -3 -4 -4 -2 -3 -4 -4 -3 1 5 -3 2 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.68 0.08 88 K -1 2 -1 -2 -2 1 -1 -3 1 1 -1 3 0 -2 -2 -1 -1 -3 -2 2 0 11 0 0 0 6 0 0 6 15 0 35 0 0 0 0 0 0 0 27 0.19 0.04 89 L -2 -3 -4 -4 -2 -3 -4 -4 -4 3 4 -3 2 0 -3 -3 -2 -2 -2 1 0 0 0 0 0 0 0 0 0 24 76 0 0 0 0 0 0 0 0 0 0.54 0.06 90 K -1 1 0 -1 -3 2 0 -2 -1 -2 -2 4 -1 -3 -2 0 3 -3 -2 -2 0 0 0 0 0 15 0 0 0 0 0 45 0 0 0 0 40 0 0 0 0.43 0.06 91 V -1 -3 -3 -3 -1 -3 -3 -4 -4 2 0 -3 0 -2 -3 -1 2 -3 -2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 85 0.48 0.08 92 D 1 -1 3 4 -2 0 1 -1 -1 -3 -3 -1 -2 -3 -2 2 1 -4 -3 -2 15 0 23 29 0 0 5 0 0 0 0 0 0 0 0 18 11 0 0 0 0.38 0.04 93 T -1 -1 -1 -2 -2 3 0 -3 -2 1 1 -1 0 -2 -2 0 1 -3 -2 2 0 0 0 0 0 35 0 0 0 0 16 0 0 0 0 5 11 0 0 33 0.21 0.05 94 A 2 -1 2 -1 -1 2 0 -1 -1 -1 -2 0 -1 -3 -2 2 1 -3 -2 0 36 0 14 0 0 16 0 0 0 0 0 0 0 0 0 18 6 0 0 11 0.23 0.04 95 N -2 -1 7 1 -4 -1 -1 -1 0 -4 -4 -1 -3 -4 -3 0 -1 -5 -3 -4 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.11 96 P 1 -2 -2 -2 -2 -2 -2 -2 -3 -1 -2 -2 1 -3 6 0 -1 -4 -3 1 15 0 0 0 0 0 0 0 0 0 0 0 6 0 55 6 0 0 0 18 0.95 0.06 97 K -1 1 3 0 -3 1 2 -2 4 -3 -3 2 -2 -2 -2 1 -1 -3 1 -3 0 6 22 0 0 5 15 0 18 0 0 19 0 0 0 10 0 0 5 0 0.34 0.04 98 T -1 -2 -1 -2 -2 -1 -2 -2 -2 -1 -2 -1 -1 -3 -2 1 6 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.81 0.11 99 P -2 -3 -3 -2 -4 -2 -2 -3 -3 -4 -4 -2 -3 -5 8 -2 -2 -5 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.31 0.12 100 K 2 2 1 -1 -3 1 1 -1 -1 -3 -3 4 -2 -3 -1 0 -1 -3 -2 -2 23 6 6 0 0 0 11 0 0 0 0 53 0 0 0 0 0 0 0 0 0.38 0.05 101 Y -2 -2 -2 -3 -3 -2 -2 -4 5 -2 -2 -2 -2 2 -4 -2 -2 1 7 -2 0 0 0 0 0 0 0 0 23 0 0 0 0 0 0 0 0 0 77 0 1.10 0.10 102 K 0 0 0 -1 -2 0 0 -2 -2 -2 -2 3 -1 -3 -1 2 3 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 36 0 0 0 19 39 0 0 6 0.34 0.05 103 F -3 -3 -4 -4 -3 -4 -4 -4 -1 -1 0 -4 -1 7 -4 -3 -3 1 4 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 88 0 0 0 0 12 0 1.08 0.10 104 V -1 2 -1 -2 -2 -1 -1 1 -2 1 -1 2 -1 -2 -2 0 1 -3 -2 1 0 12 0 0 0 0 0 16 0 15 0 23 0 0 0 5 10 0 0 18 0.12 0.03 105 R 0 2 -1 -2 -2 0 -1 -2 -2 0 -1 2 -1 -2 -2 1 3 -3 -2 1 0 19 0 0 0 0 0 0 0 0 0 15 0 0 0 11 33 0 0 22 0.23 0.04 106 I 1 -3 -3 -3 -1 -2 -3 -3 -3 3 2 -3 1 -1 -3 -2 -1 -3 -2 4 15 0 0 0 0 0 0 0 0 16 18 0 0 0 0 0 0 0 0 51 0.31 0.04 107 Q -1 3 2 -1 -3 2 0 -2 -1 -3 -3 4 -2 -4 -2 1 -1 -3 -2 -3 0 11 15 0 0 11 0 0 0 0 0 56 0 0 0 8 0 0 0 0 0.48 0.06 108 P 0 -3 -2 -2 4 -2 -2 -2 -3 -3 -3 -2 -3 -4 7 0 0 -4 -3 -2 5 0 0 0 15 0 0 0 0 0 0 0 0 0 66 6 8 0 0 0 1.32 0.08 109 G 0 -3 -1 -2 -3 -2 -3 6 -3 -5 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.31 0.09 110 Q 1 -1 0 4 -3 3 4 -2 -1 -3 -3 0 -2 -4 -2 0 -1 -3 -3 -3 16 0 0 27 0 19 39 0 0 0 0 0 0 0 0 0 0 0 0 0 0.53 0.05 111 T 2 -1 0 -1 -1 -1 -1 0 -2 -2 -2 -1 -2 -3 -1 4 3 -3 -2 -1 13 0 0 0 0 0 0 6 0 0 0 0 0 0 0 54 27 0 0 0 0.42 0.06 112 F -3 -3 -4 -4 -3 -4 -4 -4 -2 -1 0 -4 2 7 -4 -3 -3 0 2 -1 0 0 0 0 0 0 0 0 0 0 0 0 8 92 0 0 0 0 0 0 1.05 0.10 113 S 0 -1 4 0 -2 -1 -1 -1 -1 -2 -3 -1 -2 -3 -2 3 3 -4 -2 -2 0 0 35 0 0 0 0 0 0 0 0 0 0 0 0 34 31 0 0 0 0.48 0.06 114 V -1 -3 -4 -4 -1 -3 -3 -4 -4 4 2 -3 1 -1 -3 -3 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 50 8 0 0 0 0 0 0 0 0 42 0.48 0.06 115 L 1 -3 -4 -4 -2 -2 -3 -3 -3 1 4 -3 1 0 -3 -2 -1 -2 -2 0 15 0 0 0 0 0 0 0 0 0 85 0 0 0 0 0 0 0 0 0 0.48 0.06 116 A 5 -2 -2 -3 5 -2 -2 -1 -2 -2 -2 -2 -2 -3 -2 1 -1 -3 -2 -1 85 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.58 0.08 117 C 2 -3 -3 -3 9 -3 -3 -2 -3 -2 -2 -3 -2 -3 -3 0 -1 -3 -3 -1 24 0 0 0 69 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 1.09 0.09 118 Y -3 -3 -3 -4 -3 -2 -3 -4 1 -2 -2 -3 -2 3 -4 -3 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.39 0.12 119 N -2 -1 5 4 -4 0 2 2 -1 -4 -4 -1 -3 -4 -2 0 -1 -4 -3 -3 0 0 42 26 0 0 17 15 0 0 0 0 0 0 0 0 0 0 0 0 0.58 0.05 120 G 0 -3 -1 -2 -3 -2 -3 6 -3 -5 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.31 0.09 121 S 0 2 -1 -2 4 0 -1 -2 -2 -1 0 1 -1 -2 -2 1 1 -3 -2 -1 6 16 0 0 17 0 0 0 0 6 8 16 0 0 0 17 15 0 0 0 0.19 0.03 122 P 2 -2 -2 -2 -2 -2 -2 -2 -3 -1 -2 -2 -2 -3 6 0 -1 -4 -3 1 24 0 0 0 0 0 0 0 0 0 0 0 0 0 56 5 0 0 0 15 1.00 0.07 123 S 1 -1 -1 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25 0 0 41 0 0 0 0 0 0 0 0 0 0 0 0 10 0.40 0.05 229 D -1 0 0 4 -3 0 2 0 1 -3 -3 0 -2 -3 -2 1 1 -4 -2 -2 0 6 0 37 0 0 13 6 6 0 0 0 0 0 0 16 16 0 0 0 0.38 0.04 230 F -3 -3 -3 -4 -3 -3 -3 -4 0 -1 -1 -3 -1 6 -4 -3 -3 1 6 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 57 0 0 0 0 43 0 0.98 0.09 231 N -2 -1 7 1 -4 -1 -1 -1 0 -4 -4 -1 -3 -4 -3 0 -1 -5 -3 -4 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.11 232 L 0 1 1 0 -3 1 3 -2 -1 -1 0 1 -1 -2 -2 -1 0 -3 -2 1 5 8 8 0 0 0 40 0 0 0 11 7 0 0 0 0 5 0 0 16 0.20 0.03 233 V -3 -4 -5 -5 3 -3 -4 -4 -3 -2 -2 -4 -2 0 -4 -3 -3 11 1 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 81 0 11 2.24 0.13 234 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -2 -3 -1 1 -1 -3 -2 -1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.66 0.09 235 M -1 -1 -2 -3 -2 0 -2 0 -2 1 2 0 4 -1 -3 0 -1 -2 -2 1 0 0 0 0 0 6 0 7 0 0 22 11 33 0 0 8 0 0 0 14 0.16 0.04 236 K 1 1 0 2 -2 0 0 -1 1 -2 -2 2 -2 -3 -1 2 2 -3 -2 -2 17 6 0 15 0 0 0 0 6 0 0 19 0 0 0 16 21 0 0 0 0.23 0.03 237 Y -2 -1 6 0 -3 -1 -1 -1 0 -4 -4 -1 -3 -1 -3 0 -1 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-1 -1 3 -2 -2 -1 -1 -3 -1 2 0 -3 -2 0 68 0 0 0 0 0 0 0 10 0 0 0 0 0 0 16 0 0 0 5 0.39 0.06 256 Q -1 2 -1 -2 -3 2 0 -3 -1 1 -1 4 3 -2 -2 -1 -1 -3 -2 -1 0 5 0 0 0 11 0 0 0 15 0 53 16 0 0 0 0 0 0 0 0.31 0.06 257 T -1 -2 -1 -2 -2 -1 -2 -2 -2 -1 -2 -1 -1 -3 -2 1 6 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.81 0.11 258 G 0 -3 -1 -2 -3 -2 -3 6 -3 -5 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.31 0.09 259 I -1 -3 -3 -4 -1 -1 -3 -4 -3 3 0 -2 0 -1 -3 -2 -1 -3 1 4 0 0 0 0 0 5 0 0 0 19 0 0 0 0 0 0 0 0 5 71 0.40 0.06 260 A 2 -1 0 2 2 -1 0 -1 -1 -2 -2 -1 -2 -2 -1 3 1 -3 -2 -1 17 1 1 13 6 1 1 1 0 1 1 1 0 1 1 47 6 0 0 1 0.28 0.04 261 V -1 -2 -3 -3 -1 -2 -2 -3 -3 3 1 -2 1 -1 -2 -2 0 -3 -1 4 1 1 1 1 0 1 1 1 0 11 7 1 0 1 1 1 1 0 0 70 0.33 0.05 262 L -1 -1 -1 1 -3 2 5 0 -1 -2 0 0 -1 -2 -1 -1 -1 -2 -2 -2 1 1 1 1 0 6 64 7 0 1 12 1 0 1 1 1 1 0 0 1 0.42 0.05 263 D -1 3 0 3 -3 3 1 -2 -1 -3 -3 2 -2 -4 -2 0 1 -3 -2 -3 0 26 0 26 0 27 0 0 0 0 0 11 0 0 0 0 11 0 0 0 0.44 0.05 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0 16 0 0.38 0.05 273 Q -1 0 3 0 -2 2 0 0 4 -2 -2 1 0 -2 -2 1 -1 -3 -1 -1 1 1 25 1 0 11 1 7 17 1 1 12 6 0 1 9 1 0 0 8 0.20 0.03 274 N 1 0 4 0 -2 0 1 -1 -1 -3 -3 2 -2 -3 -1 1 1 -3 -2 -2 13 0 35 0 0 0 6 0 0 0 0 24 0 0 0 13 6 0 0 0 0.31 0.04 275 G 0 -2 -1 -1 -2 0 -1 6 -2 -3 -3 -1 -2 -3 -2 0 -1 -2 -3 -3 1 1 1 1 0 8 1 74 0 1 1 1 0 0 1 8 1 0 0 1 0.76 0.05 276 M -1 -3 -4 -4 -3 -3 -3 -3 -2 -1 0 -3 2 7 -4 -2 -2 4 2 -1 8 0 0 0 0 0 0 0 0 0 0 0 11 74 0 0 0 7 0 0 0.78 0.08 277 N -1 -1 2 -1 2 4 0 4 -1 -4 -3 0 -2 -4 -2 -1 -1 -3 -3 -3 0 0 11 0 8 39 0 42 0 0 0 0 0 0 0 0 0 0 0 0 0.53 0.06 278 G 0 -3 -1 -2 -3 -2 -3 6 -3 -4 -4 -2 -3 -3 -3 -1 -2 4 -3 -4 0 0 0 0 0 0 0 92 0 0 0 0 0 0 0 0 0 8 0 0 1.20 0.08 279 R -1 4 -1 1 -4 1 0 0 -1 -4 -3 4 -2 -4 -2 -1 -1 -3 -2 -3 0 40 0 7 0 0 0 8 0 0 0 45 0 0 0 0 0 0 0 0 0.55 0.06 280 T -1 -1 1 -1 -2 4 0 -2 -1 -2 -2 0 -1 -3 1 2 3 -3 -2 -2 0 0 6 0 0 33 0 0 0 0 0 0 0 0 7 14 40 0 0 0 0.41 0.06 281 I -2 -4 -4 -4 -2 -4 -4 -5 -4 6 1 -3 1 -1 -4 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 100 0 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0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 1.04 0.10 291 F -2 -3 -3 -4 -3 -3 -3 -4 2 0 2 -3 0 6 -4 -3 -2 0 2 -1 0 0 0 0 0 0 0 0 8 0 31 0 0 61 0 0 0 0 0 0 0.62 0.07 292 T 0 -2 -1 -2 -1 -1 -1 -2 -2 -1 -2 -1 -1 -3 -2 2 6 -3 -2 -1 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 88 0 0 0 0.67 0.09 293 P -1 -3 -3 -2 -3 -2 -2 -3 -3 -1 0 -2 -2 -3 7 -1 0 -4 -3 -2 0 0 0 0 0 0 0 0 0 6 12 0 0 0 76 0 6 0 0 0 1.48 0.08 294 F 0 -1 1 2 -2 0 2 0 -1 -2 -2 -1 -2 1 -2 2 1 -2 1 -2 6 0 6 10 0 0 20 6 0 0 0 0 0 11 0 22 11 0 8 0 0.19 0.03 295 D -1 -1 0 5 -4 0 4 -2 -1 -4 -4 0 -3 -4 -2 1 -1 -4 -3 -3 0 0 0 50 0 0 35 0 0 0 0 0 0 0 0 15 0 0 0 0 0.71 0.06 296 V -1 -3 -4 -4 -1 -3 -3 -4 -4 3 0 -3 0 -1 -3 -2 -1 -4 -2 5 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 92 0.59 0.08 297 V -1 -2 1 -2 -2 -2 -2 0 -1 2 0 -2 0 3 -3 -2 -1 -1 3 2 0 0 16 0 0 0 0 8 0 11 0 0 0 15 0 0 0 0 16 35 0.18 0.04 298 R -2 4 2 -1 -3 3 0 -2 -1 -2 -2 2 2 -3 -2 -1 -1 -3 -2 -2 0 35 15 0 0 16 0 0 0 0 0 18 16 0 0 0 0 0 0 0 0.39 0.05 299 Q -2 0 -1 -1 -4 7 1 -3 0 -4 -3 1 -1 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.08 0.12 300 C -1 -3 -3 -4 3 -2 -3 -4 -3 2 2 -2 5 -1 -3 -2 -1 -2 -2 2 0 0 0 0 11 0 0 0 0 12 16 0 43 0 0 0 0 0 0 18 0.39 0.06 301 S 1 -2 -2 -3 -2 -1 -2 1 0 -1 0 -2 2 2 -2 0 -1 0 4 -1 16 0 0 0 0 0 0 15 0 0 8 0 16 6 0 11 0 0 29 0 0.22 0.04 302 G 0 -3 -1 -2 -3 -2 -3 6 -3 -5 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.31 0.09 303 V -1 -3 -4 -4 -1 -3 -3 -4 -4 3 0 -3 0 -1 -3 -2 -1 -4 -2 5 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 94 0.60 0.08 304 T -1 2 3 -1 -3 0 -1 -2 -1 -1 -2 2 -1 -3 -2 0 2 -4 -2 0 0 15 29 0 0 0 0 0 0 0 0 24 0 0 0 0 17 0 0 16 0.26 0.04 305 F -2 -3 -4 -4 -2 -2 -3 -4 -3 1 4 -3 4 2 -3 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 0 0 74 0 16 11 0 0 0 0 0 0 0.51 0.06 306 Q -2 0 -1 -1 -4 7 1 -3 0 -4 -3 1 -1 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.08 0.12 K Lambda Standard Ungapped 0.1378 0.3228 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1378 0.3228 PSI Gapped 0.0410 0.2670