Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 K -1 2 0 -1 -3 1 1 -2 -1 -3 -3 5 -1 -3 -1 0 -1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.51 0.00 2 I -1 -3 -3 -3 -1 -3 -3 -4 -3 4 1 -3 1 -1 -3 -2 0 -3 -1 4 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 50 0.34 0.01 3 V 0 -3 -3 -3 -1 -2 -3 -3 -3 3 1 -2 1 -1 -3 -2 0 -3 -1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.34 0.00 4 N 0 -1 5 1 -2 0 0 0 0 -3 -3 0 -2 -3 -1 3 1 -4 -2 -2 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0.45 0.01 5 N 0 -1 3 0 -1 0 0 -1 -1 -2 -2 0 -2 -3 -1 3 3 -3 -2 -1 0 0 30 0 0 0 0 0 0 0 0 0 0 0 0 40 30 0 0 0 0.36 0.00 6 W -3 -3 -4 -5 -3 -2 -3 -3 -3 -3 -2 -3 -2 1 -4 -3 -3 12 2 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 2.36 0.01 7 L -2 2 -3 -4 -2 -2 -2 -4 -2 1 3 -1 1 2 -3 -2 -2 -1 0 0 0 19 0 0 0 0 0 0 0 0 66 0 0 14 0 0 0 0 0 0 0.30 0.02 8 K -1 3 0 -1 -4 1 1 -2 -1 -3 -3 5 -2 -4 -1 -1 -1 -3 -2 -3 0 19 0 0 0 0 0 0 0 0 0 81 0 0 0 0 0 0 0 0 0.59 0.04 9 Q -1 0 -1 -1 -2 4 0 2 -1 0 0 0 0 -2 -2 -1 -1 -2 -2 1 0 0 0 0 0 47 0 20 0 0 14 0 0 0 0 0 0 0 0 19 0.21 0.02 10 L -2 -3 -3 -4 -2 -2 -3 -4 -1 2 3 -3 1 1 -3 -3 -1 -1 3 1 0 0 0 0 0 0 0 0 0 17 63 0 0 0 0 0 0 0 20 0 0.37 0.02 11 I -1 -1 -3 -3 -1 -2 -2 -3 -3 3 2 0 1 -1 -3 -2 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 33 14 16 0 0 0 0 0 0 0 37 0.22 0.02 12 K -1 0 -1 -2 -3 2 0 -3 4 1 1 2 0 -1 -2 -1 -1 -3 -1 0 0 0 0 0 0 16 0 0 19 17 20 28 0 0 0 0 0 0 0 0 0.16 0.02 13 V 0 -3 -3 -4 -1 -2 -3 -3 -3 2 3 -2 1 -1 -3 -2 -1 -3 -1 3 11 0 0 0 0 0 0 0 0 0 39 0 0 0 0 0 0 0 0 49 0.29 0.03 14 T -1 -2 -1 -2 -2 -2 -2 -3 -2 0 -1 -2 -1 3 -2 0 4 -2 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 63 0 0 12 0.36 0.05 15 L -2 1 -3 -4 -2 -2 -3 -4 -2 1 3 -2 3 2 -3 -2 -2 5 0 0 0 13 0 0 0 0 0 0 0 9 46 0 12 11 0 0 0 10 0 0 0.32 0.04 16 V -1 -2 -3 -3 3 0 -2 -4 -3 2 2 -2 1 1 -3 -2 -1 -2 -1 3 0 0 0 0 9 10 0 0 0 8 30 0 0 8 0 0 0 0 0 35 0.23 0.04 17 F -1 -3 -3 -4 5 -3 -3 -4 -2 1 1 -3 0 3 -3 -2 -1 5 2 2 0 0 0 0 19 0 0 0 0 0 20 0 0 17 0 0 0 10 11 23 0.39 0.04 18 L -1 -3 -3 -3 -2 -3 -3 -3 -3 2 3 -3 1 3 -3 -1 -1 -1 0 2 0 0 0 0 0 0 0 0 0 9 35 0 0 22 0 8 0 0 0 26 0.27 0.04 19 F -1 -3 -3 -4 -2 -3 -3 -3 -2 0 2 -3 0 5 -3 -2 0 0 1 1 7 0 0 0 0 0 0 0 0 0 23 0 0 52 0 0 7 0 0 10 0.41 0.06 20 V 0 -3 -3 -4 3 -3 -3 -3 -3 2 1 -3 2 2 -3 -2 -1 -2 0 3 8 0 0 0 8 0 0 0 0 17 10 0 7 16 0 0 0 0 0 34 0.24 0.04 21 A 3 -2 1 -2 3 -2 -2 -1 -2 1 -1 -2 -1 -2 -2 0 -1 4 -1 1 47 0 10 0 9 0 0 0 0 8 0 0 0 0 0 0 0 8 0 18 0.24 0.05 22 A 2 -2 1 -2 -2 -1 -2 0 2 0 0 -1 -1 -2 2 0 0 -3 -2 1 26 0 10 0 0 0 0 9 8 0 8 0 0 0 10 0 8 0 0 22 0.13 0.03 23 I 0 -2 -3 -3 -2 1 -2 -3 -2 1 3 -2 1 1 -2 -2 -1 -2 -1 0 9 0 0 0 0 11 1 1 0 8 58 0 0 8 0 1 0 0 0 1 0.23 0.04 24 F -1 -2 -2 -3 4 -2 -2 -2 -1 0 0 -2 1 3 -3 0 -1 5 2 -1 1 0 0 0 16 0 1 1 0 8 8 0 7 25 0 14 0 10 8 1 0.28 0.04 25 Y -2 -3 -3 -3 2 -2 -3 0 -1 1 -1 -3 -1 3 -3 -2 -2 6 5 0 1 0 0 0 7 0 1 8 0 10 1 0 0 18 0 1 0 14 28 9 0.43 0.05 26 L 0 -2 -3 -3 2 -2 -3 0 -2 1 3 -2 1 2 -2 -1 -1 -1 0 1 9 0 0 1 7 0 1 10 0 0 45 1 0 14 0 1 1 0 0 8 0.17 0.03 27 I -1 -3 -3 -3 7 -3 -3 -3 -3 3 1 -3 0 -1 -3 -2 -1 -2 -2 2 1 0 0 1 37 0 1 1 0 30 16 1 0 0 0 1 1 0 0 10 0.47 0.06 28 T 0 -2 -1 -2 -1 -1 -2 -2 -2 0 1 -1 3 -1 -2 2 2 -3 -2 1 0 0 0 0 0 0 0 0 0 0 21 0 14 0 0 33 16 0 0 15 0.19 0.05 29 P -1 -2 -3 -2 -2 -2 -2 -3 -3 0 0 -2 -1 1 6 -2 -1 -3 -1 1 1 0 0 0 0 0 1 1 0 0 8 0 0 10 52 1 0 0 0 24 0.83 0.06 30 V 0 -2 -2 -2 -2 -2 -2 -2 -1 1 0 -2 0 0 -2 0 1 6 3 1 7 0 0 0 0 0 1 1 0 10 9 0 0 0 0 7 15 17 16 15 0.29 0.03 31 H 0 -2 -1 1 -2 -1 -1 -2 4 -2 -1 -1 -1 3 -2 1 -1 0 4 -2 8 0 0 10 0 0 1 1 14 0 1 0 0 22 0 16 0 0 24 1 0.28 0.04 32 V 0 -2 0 -2 -1 -1 -2 -2 -1 1 0 -1 0 -1 -2 1 1 -2 1 2 1 0 7 0 0 0 1 1 0 10 8 0 0 0 0 22 8 0 10 31 0.11 0.03 33 M 2 -2 -2 -3 -1 -1 -2 -2 -2 1 1 -2 5 -1 -2 -1 1 -2 -2 1 24 0 0 0 0 0 1 1 0 7 8 0 37 0 0 1 10 0 0 8 0.20 0.05 34 S 1 1 0 -1 -1 -1 -1 -1 2 -1 -2 0 -1 -2 1 2 3 -3 -1 0 7 10 0 0 0 0 1 1 7 0 1 0 0 0 8 21 34 0 0 8 0.23 0.04 35 K -1 0 -1 -1 -2 3 0 -2 -1 -1 -2 1 -1 -3 3 1 2 -3 -2 0 1 0 0 0 0 23 1 1 0 0 1 14 0 0 17 9 24 0 0 8 0.32 0.04 36 H -1 -1 -1 -2 -1 -1 -1 -2 3 1 0 -1 0 1 -2 1 0 -1 2 2 1 1 1 1 0 1 1 1 14 1 10 1 0 9 1 17 1 0 8 31 0.10 0.03 37 T 0 -1 1 1 -2 -1 0 -2 -1 -1 0 -1 -1 0 -2 1 1 -1 2 -1 8 0 7 8 0 0 8 1 0 0 17 1 0 0 0 15 17 0 16 1 0.10 0.02 38 D -1 -2 0 4 -2 -1 0 0 -2 1 -1 -2 -1 3 -2 0 -1 -2 0 0 1 0 0 36 0 0 1 8 0 15 1 1 0 20 0 8 1 0 0 7 0.19 0.04 39 F -2 -2 0 0 -3 -1 0 -3 3 1 -1 -2 -1 4 -3 -2 -2 0 3 -1 0 0 6 7 0 0 8 0 13 17 0 0 0 36 0 0 0 0 14 0 0.30 0.05 40 S 0 -1 0 1 -2 1 2 -2 2 -2 -2 1 -2 -3 -2 2 1 -3 -2 -1 0 0 0 6 0 7 22 0 8 0 0 7 0 0 0 36 7 0 0 8 0.27 0.04 41 S 2 -2 1 2 -2 -1 0 1 -1 -2 -1 -1 -1 -1 -2 2 1 -2 1 -1 22 0 7 19 0 0 0 8 0 0 7 0 0 0 0 21 7 0 9 0 0.18 0.03 42 E -1 2 1 1 -3 2 3 -2 0 -3 -3 1 -2 -3 1 0 -1 -3 -2 -3 1 20 9 7 0 15 28 1 0 0 1 0 0 0 7 8 0 0 0 1 0.37 0.04 43 I -1 -3 -2 -3 -2 -2 -3 1 -3 3 1 -2 2 1 -3 -2 -1 -2 -1 3 1 0 0 0 0 0 0 15 0 33 1 0 7 8 0 1 0 0 0 31 0.20 0.04 44 I 1 -2 -2 -2 -2 -1 0 -2 -1 1 1 -2 0 0 -2 0 0 -1 3 1 13 0 0 0 0 0 8 0 0 13 19 0 0 0 0 7 7 0 22 9 0.13 0.03 45 G 0 -2 0 4 -3 -1 0 3 -2 -3 -4 -1 -3 -4 -2 2 1 -4 -3 -3 0 0 0 33 0 0 0 32 0 0 0 0 0 0 0 24 11 0 0 0 0.49 0.07 46 Y -3 -3 -3 -4 -3 -3 -4 -4 0 -1 -1 -3 -1 6 -4 -3 -3 1 6 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 55 0 0 0 0 45 0 1.07 0.13 47 K -1 1 -1 -2 -4 1 0 -2 -2 -3 -2 6 2 -3 -2 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 87 13 0 0 0 0 0 0 0 0.72 0.13 48 A 1 -3 -3 -4 -2 -2 -3 -3 -1 1 0 -3 0 0 -3 -2 -1 -1 4 4 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 64 0.42 0.10 49 I -2 -4 -4 -4 -2 -3 -4 -5 -4 6 2 -3 1 -1 -4 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 85 10 0 0 0 0 0 0 0 0 5 0.66 0.11 50 D -2 -1 0 5 -4 1 4 -2 -1 -4 -4 1 -3 -4 -2 -1 -1 -4 -3 -3 0 0 0 46 0 6 36 0 0 0 0 13 0 0 0 0 0 0 0 0 0.72 0.09 51 G -2 -1 6 1 -3 0 -1 0 0 -4 -4 2 -3 -4 -2 1 -1 -4 -3 -4 0 0 69 6 0 0 0 5 0 0 0 14 0 0 0 6 0 0 0 0 0.72 0.11 52 G 1 -3 -1 -2 -3 -2 -3 6 -3 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 7 0 0 0 0 0 0 93 0 0 0 0 0 0 0 0 0 0 0 0 1.22 0.12 53 V -1 -2 -3 -3 -2 2 -2 -4 -3 3 0 -2 0 -2 -3 -2 -1 -3 -2 4 0 0 0 0 0 19 0 0 0 23 0 0 0 0 0 0 0 0 0 58 0.38 0.09 54 T -1 -3 -3 -4 -2 -3 -3 -4 -3 3 3 -3 1 -1 -3 -2 1 -3 -2 3 0 0 0 0 0 0 0 0 0 30 37 0 0 0 0 0 11 0 0 23 0.36 0.06 55 R -2 6 -1 -2 -4 2 0 -3 -1 -4 -3 3 -2 -4 -2 -1 -2 -3 -2 -3 0 62 0 0 0 13 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0.79 0.11 56 D -1 -2 1 5 -3 0 2 -2 -2 -2 -3 -1 -2 -3 1 0 0 -4 -3 0 0 0 6 48 0 0 14 0 0 0 0 0 0 0 7 6 6 0 0 13 0.47 0.07 57 I -2 -4 -4 -4 -2 -4 -4 -4 -3 4 1 -3 0 5 -4 -3 -2 -1 1 2 0 0 0 0 0 0 0 0 0 48 0 0 0 38 0 0 0 0 0 15 0.52 0.09 58 A 1 -1 1 3 -2 0 2 -2 -1 -1 -2 -1 -1 -3 -2 1 1 -4 -2 1 10 0 6 19 0 0 19 0 0 0 0 0 0 0 0 14 13 0 0 20 0.21 0.04 59 S 1 -1 1 2 -2 -1 -1 -1 -2 -1 -2 0 -2 -3 4 2 0 -4 -3 0 13 0 6 13 0 0 0 0 0 0 0 6 0 0 23 25 0 0 0 14 0.36 0.05 60 T 0 -1 1 1 -2 0 2 -2 -1 -3 -3 -1 -2 -3 4 1 2 -4 -3 -2 7 0 10 6 0 0 19 0 0 0 0 0 0 0 25 11 22 0 0 0 0.48 0.06 61 D -2 -3 0 6 -3 -1 0 -3 -2 1 1 -2 -1 -2 -3 -1 -2 -4 -3 -1 0 0 0 62 0 0 0 0 0 13 25 0 0 0 0 0 0 0 0 0 0.55 0.10 62 T 0 0 2 2 -2 1 0 -1 2 -2 -1 1 -1 -3 -2 1 2 -3 -2 -1 10 0 13 12 0 7 0 0 6 0 5 12 0 0 0 13 17 0 0 5 0.17 0.03 63 C -1 -5 -4 -5 11 -4 -5 -4 -4 -2 -2 -4 -3 -4 -4 -2 -2 -3 -4 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.09 0.20 64 F -2 -4 -4 -4 -2 -4 -4 -4 -3 1 0 -4 0 6 -4 -3 -2 -1 2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 62 0 0 0 0 0 38 0.69 0.11 65 A 3 2 -1 -2 -2 -1 -1 -1 5 -3 -3 -1 -2 -3 -2 1 -1 -3 -1 -2 48 13 0 0 0 0 0 0 25 0 0 0 0 0 0 14 0 0 0 0 0.39 0.09 66 N -2 -1 7 1 -4 -1 -1 -1 0 -4 -5 -1 -3 -4 -3 0 -1 -5 -3 -4 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.24 0.17 67 K 0 1 -1 -2 -3 0 0 -2 -2 -1 -2 5 -1 -3 -2 -1 1 -4 -2 1 6 0 0 0 0 0 0 0 0 0 0 62 0 0 0 0 13 0 0 19 0.36 0.09 68 H -3 -3 -3 -4 -3 -3 -3 -4 4 -1 -1 -3 -1 6 -4 -3 -3 0 5 -2 0 0 0 0 0 0 0 0 16 0 0 0 0 61 0 0 0 0 23 0 0.88 0.12 69 A 0 0 0 1 -2 1 1 0 -1 0 -1 1 -1 0 -2 0 -1 -3 -1 1 11 6 5 6 0 5 11 5 0 6 0 13 0 5 0 7 0 0 0 20 0.06 0.02 70 D 0 -1 4 1 -3 2 0 2 2 -4 -4 -1 -2 -3 -2 1 -1 -4 -2 -3 7 0 39 5 0 14 0 18 5 0 0 0 0 0 0 11 0 0 0 0 0.42 0.07 71 F -3 -4 -4 -5 -3 -4 -4 -4 -2 -1 0 -4 -1 8 -5 -3 -3 0 2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 1.32 0.16 72 D 0 -2 2 5 -3 0 2 0 -1 -3 -4 -1 -3 -4 -2 1 0 -4 -3 -3 6 0 13 45 0 0 14 7 0 0 0 0 0 0 0 10 6 0 0 0 0.51 0.07 73 T 1 0 1 2 -3 4 1 -2 -1 -2 -2 1 -1 -3 -2 1 0 -3 -2 -1 14 0 7 13 0 32 6 0 0 0 0 10 0 0 0 6 5 0 0 6 0.29 0.05 74 W -4 -4 -5 -5 -4 -3 -4 -4 -3 -3 -2 -4 -2 3 -5 -4 -4 12 2 -4 0 0 0 0 0 0 0 0 0 0 0 0 0 14 0 0 0 86 0 0 2.66 0.21 75 F -3 -2 -2 -4 -3 -2 -3 -4 5 -2 -1 -3 -1 5 -4 -3 -3 6 6 -2 0 0 0 0 0 0 0 0 19 0 0 0 0 34 0 0 0 14 33 0 0.89 0.11 76 S 0 0 2 1 -2 1 2 -1 2 -3 -3 1 -2 -3 -1 2 0 -3 -2 -2 7 1 17 7 0 1 21 1 6 1 1 13 0 1 1 19 1 0 0 1 0.26 0.04 77 Q 2 0 1 0 -2 2 2 -1 -1 -2 -2 1 -1 -3 -1 1 0 -2 -2 -1 32 1 8 1 0 11 17 1 0 1 1 7 0 1 1 15 1 0 0 1 0.23 0.04 78 R -1 3 0 -1 -3 0 0 -2 4 -2 -2 3 -1 0 -2 0 1 -2 0 -2 1 19 1 1 0 1 1 1 16 1 1 32 0 7 1 1 15 0 0 1 0.27 0.05 79 G -1 -3 -2 -3 -3 -3 -3 4 2 -2 -2 -3 -2 4 -3 -2 -2 -1 3 -3 0 0 0 0 0 0 0 47 6 0 0 0 0 33 0 0 0 0 14 0 0.60 0.09 80 G -1 0 -1 -2 -3 -2 -2 6 -2 -4 -4 0 -3 0 -3 -1 -2 -3 -3 -4 0 7 0 0 0 0 0 79 0 0 0 7 0 6 0 0 0 0 0 0 0.89 0.10 81 S 0 -2 -1 -2 -2 -1 -2 -2 -1 0 0 -2 -1 2 1 2 2 -2 2 1 0 0 0 0 0 0 0 0 0 0 5 0 0 13 7 36 13 0 9 17 0.19 0.06 82 Y -2 -3 -3 -4 -3 -2 -3 -4 0 1 -1 -3 -1 2 2 -2 -2 1 6 1 0 0 0 0 0 0 0 0 0 13 0 0 0 5 13 0 0 0 57 12 0.66 0.10 83 T -1 2 1 2 -2 0 1 -2 1 -1 -1 0 -1 -2 -2 0 3 -3 -2 0 0 15 5 13 0 0 7 0 5 0 6 0 0 0 0 5 30 0 0 14 0.16 0.05 84 N -2 -1 7 0 -4 -1 -1 -1 0 -4 -3 -1 -3 2 -3 0 -1 -3 -2 -3 0 0 87 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0.96 0.15 85 D 0 -1 2 3 -2 -1 0 0 -1 -3 -4 0 -3 -3 -2 4 0 -4 -3 -3 0 0 13 22 0 0 0 7 0 0 0 6 0 0 0 52 0 0 0 0 0.44 0.08 86 K -1 3 -1 0 -3 1 0 -3 -1 0 -1 3 1 -3 1 -1 -1 -3 -2 0 0 21 0 6 0 6 0 0 0 11 0 35 10 0 6 0 0 0 0 5 0.25 0.06 87 A 1 0 3 1 -2 0 0 1 -1 -3 -3 1 -2 -3 -2 2 1 -4 -2 -2 14 6 20 10 0 0 0 7 0 0 0 6 0 0 0 30 6 0 0 0 0.29 0.05 88 C -1 -5 -4 -5 11 -4 -5 -4 -4 -2 -2 -4 -3 -4 -4 -2 -2 -3 -4 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.09 0.20 89 P -2 -3 -3 -2 -4 -2 -2 -3 -3 -4 -4 -2 -4 -5 8 -2 -2 -5 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.38 0.18 90 L -2 -3 -4 -4 -2 -3 -4 -4 -4 5 2 -3 2 -1 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 67 11 0 7 0 0 0 0 0 0 15 0.53 0.09 91 I -1 -3 -3 -3 -1 -3 -3 -4 -4 2 0 -3 0 -2 -3 -2 2 -4 -2 5 0 0 0 0 0 0 0 0 0 5 0 0 0 0 0 0 16 0 0 79 0.50 0.11 92 A 1 -3 -3 -3 -1 -2 -3 0 -3 2 1 -2 0 -2 -3 -1 1 -3 -2 4 11 0 0 0 0 0 0 7 0 5 6 0 0 0 0 0 14 0 0 57 0.27 0.07 93 A 3 -2 -1 -2 -2 -2 -2 4 -2 -2 -2 -2 -2 -3 -2 0 0 -3 -3 0 48 0 0 0 0 0 0 39 0 0 0 0 0 0 0 0 7 0 0 7 0.48 0.08 94 V -1 -3 -3 -4 -1 -3 -3 -4 -4 2 0 -3 0 -2 -3 -2 1 -4 -2 5 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 12 0 0 82 0.53 0.11 95 I -1 -2 -2 -2 -1 -2 -2 -3 -2 4 1 -2 1 1 -2 -1 -1 -2 -1 2 1 1 1 1 0 1 1 1 0 51 2 1 5 7 1 8 1 0 1 15 0.22 0.05 96 T 1 -1 0 4 -2 0 1 -1 -1 -2 -2 -1 -2 0 -1 1 1 -3 -2 -2 17 1 1 35 0 1 7 1 0 1 1 1 0 6 1 14 11 0 0 1 0.28 0.04 97 R -1 2 0 2 -3 1 0 3 -1 -3 -1 0 -2 -3 -2 1 -1 -3 -2 -2 0 17 0 14 0 9 5 31 0 0 7 0 0 0 0 13 0 0 0 0 0.27 0.04 98 E -2 -2 0 4 -3 0 3 -3 -2 1 -2 -1 -2 -3 -2 -1 -1 -4 -3 1 0 0 0 40 0 0 30 0 0 14 0 0 0 0 0 0 0 0 0 16 0.43 0.08 99 V 1 -2 1 -1 -1 -1 0 -2 -2 2 0 -1 0 0 -2 -1 -1 -2 -1 2 17 1 14 1 0 1 7 1 0 22 7 1 0 5 1 1 1 0 0 20 0.07 0.03 100 G 0 0 -1 -2 -3 -2 -2 5 -2 -2 -2 -1 1 -3 -2 -1 -2 -3 -3 -1 7 7 0 0 0 0 0 69 0 0 1 0 7 0 0 0 0 0 0 7 0.65 0.08 101 F 1 1 2 -1 -2 -1 -1 -1 1 -2 -2 0 -1 1 -2 1 1 -2 1 -1 16 13 13 0 0 0 0 0 5 0 1 0 0 11 0 17 15 0 6 0 0.15 0.04 102 V -1 2 -2 -3 -2 -1 -2 -3 -2 2 1 -1 1 -2 1 -1 2 -3 -2 2 0 16 0 0 0 0 0 0 0 12 7 0 6 0 7 0 27 0 0 26 0.19 0.05 103 V 1 -3 -3 -3 -1 -2 -3 -3 -3 3 1 -2 1 -1 -2 -1 -1 -3 -2 4 15 0 0 0 0 0 0 0 0 18 5 0 5 0 0 0 0 0 0 53 0.30 0.06 104 P 0 -3 -3 -2 -3 -2 -2 -3 -3 -2 -2 -2 -2 2 7 -1 0 -3 -1 -1 12 0 0 0 0 0 0 0 0 0 0 0 0 14 60 0 7 0 0 7 1.09 0.10 105 G -1 -2 3 3 -3 -2 -1 5 -2 -4 -4 -2 -3 -4 -3 0 -2 -4 -4 -4 0 0 25 18 0 0 0 57 0 0 0 0 0 0 0 0 0 0 0 0 0.76 0.09 106 L -1 -3 -4 -4 -1 -3 -3 -4 -4 3 2 -3 1 -1 -3 -3 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 13 23 0 0 0 0 0 0 0 0 64 0.48 0.08 107 P -2 -3 -3 -2 -4 -2 -2 -3 -3 -4 -4 -2 -4 -5 8 -2 -2 -5 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.38 0.18 108 G 3 -2 -1 -2 -1 -1 -1 3 -2 -2 -2 -1 -2 -3 -1 1 2 -3 -2 -1 43 0 0 0 0 0 0 25 0 0 0 0 0 0 0 7 21 0 0 0 0.37 0.06 109 T -1 1 2 -1 -3 -1 -1 1 -1 -2 -2 1 -2 2 -2 0 2 -1 2 -2 0 7 18 0 0 0 0 12 0 0 0 14 0 14 0 0 21 0 13 0 0.19 0.05 110 I -1 -3 -3 -3 -1 -3 -3 -3 -3 2 0 -3 0 1 -3 -2 0 -3 -1 5 0 0 0 0 0 0 0 0 0 5 0 0 0 8 0 0 6 0 0 77 0.43 0.09 111 L 0 -2 -2 -3 -2 -2 -2 -2 -1 0 3 -2 1 2 -2 1 -1 -1 3 0 12 0 0 0 0 0 0 0 0 0 43 0 0 6 0 15 0 0 19 0 0.21 0.05 112 R 0 3 -2 -3 -2 -1 -2 -3 -2 -1 2 0 0 -1 -3 -2 -2 7 -1 -1 11 32 0 0 0 0 0 0 0 0 32 0 0 0 0 0 0 19 0 0 0.43 0.07 113 T 1 -3 -3 -3 -2 -2 -2 -3 -1 1 -1 -2 -1 0 -3 0 0 5 4 3 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 5 11 20 46 0.33 0.08 114 T 0 -1 -1 -1 -1 -1 -1 1 -1 1 1 -1 2 -1 -1 0 0 -1 -1 1 4 2 2 2 1 2 3 16 1 9 10 3 15 2 2 3 8 1 1 14 0.04 0.01 115 N -1 0 2 2 -2 0 0 2 -1 -1 -2 0 -1 -2 -1 0 1 -2 -2 -1 2 7 18 16 1 1 2 22 1 2 3 2 1 1 2 2 9 0 1 9 0.16 0.02 116 G -1 0 1 -2 -3 0 -2 5 -1 -3 -3 -1 -2 1 -2 -1 -2 -2 0 -3 1 6 6 0 0 6 0 63 0 0 1 0 0 10 0 1 0 0 5 0 0.58 0.07 117 D -1 2 0 1 -3 2 0 -2 3 -1 -1 3 2 -2 -2 -1 0 -3 -1 -2 0 13 0 11 0 11 0 0 14 5 0 25 14 0 0 0 7 0 0 0 0.23 0.06 118 F -1 -2 -2 -2 -2 -2 -2 -3 -2 1 1 -2 0 3 -2 1 2 -2 0 2 0 0 0 0 0 0 0 0 0 11 7 0 0 25 0 19 19 0 0 19 0.20 0.05 119 L -2 -3 -4 -4 -2 -3 -4 -4 -4 2 4 -3 2 0 -3 -3 -1 -2 -2 2 0 0 0 0 0 0 0 0 0 13 75 0 0 0 0 0 0 0 0 12 0.54 0.08 120 H -1 -2 -1 -2 -2 -1 -2 -3 6 1 0 -2 0 1 1 -2 -1 -3 0 2 0 0 0 0 0 0 0 0 39 13 6 0 0 6 8 0 0 0 0 26 0.34 0.07 121 F -3 -3 -4 -4 -3 -4 -4 -4 -1 -1 1 -4 -1 7 -4 -3 -3 0 4 -1 0 0 0 0 0 0 0 0 0 0 7 0 0 78 0 0 0 0 14 0 1.01 0.13 122 L 2 -3 -3 -3 -1 -2 -3 -2 -3 3 2 -2 1 -1 -2 -1 0 -3 -2 2 25 0 0 0 0 0 0 0 0 23 22 0 0 0 0 0 6 0 0 23 0.23 0.05 123 P -1 -2 1 -2 -2 0 -1 -2 -2 1 0 -1 1 -2 4 1 1 -3 -2 0 0 0 7 0 0 6 0 0 0 19 6 0 6 0 25 16 14 0 0 0 0.32 0.05 124 R 0 3 3 -1 -3 1 -1 -2 3 -3 -3 0 -2 -1 -2 0 1 -2 2 -2 6 27 19 0 0 6 0 0 9 0 0 0 0 0 0 6 14 0 12 0 0.28 0.06 125 V 3 -2 -2 -3 -1 -2 -2 0 -3 0 -1 -2 -1 -2 -2 0 1 6 -1 2 39 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 12 14 0 27 0.33 0.07 126 F 1 -3 -3 -4 -2 -3 -3 -3 -2 1 1 -3 0 6 -3 -2 -2 -1 1 0 19 0 0 0 0 0 0 0 0 12 12 0 0 57 0 0 0 0 0 0 0.49 0.09 127 S 1 -2 2 -1 -2 -2 -2 2 -1 -2 -1 -2 -1 4 -2 1 -1 -1 0 -2 21 0 14 0 0 0 0 14 0 0 0 0 0 31 0 16 0 0 0 0 0.22 0.05 128 A 2 1 2 -1 -2 -1 -1 3 -1 -3 -3 0 -2 -3 -2 1 0 -3 -3 -2 28 14 12 0 0 0 0 31 0 0 0 0 0 0 0 10 5 0 0 0 0.35 0.05 129 V -1 -2 2 2 -2 -2 -1 -2 -2 1 -1 -2 -1 -2 -2 0 2 -4 -2 3 0 0 12 14 0 0 0 0 0 0 0 0 0 0 0 5 24 0 0 45 0.23 0.07 130 G 1 0 1 -1 -2 -1 -2 4 -2 -3 -3 -1 -2 -3 -2 2 2 -3 -3 -2 6 5 5 0 0 0 0 49 0 0 0 0 0 0 0 17 18 0 0 0 0.51 0.07 131 N 0 -1 4 0 -2 -1 -1 2 -1 -1 -2 -1 -1 -2 -1 1 0 -2 -2 0 2 1 35 1 0 1 1 20 0 1 2 1 0 1 1 14 1 0 1 15 0.24 0.04 132 I -1 -2 -2 -2 -1 1 -1 -3 -2 2 1 -1 2 -1 -2 -2 -1 -2 -1 3 1 1 1 1 0 15 1 1 0 11 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0.06 486 L -2 -3 -4 -4 -2 -3 -4 -4 -4 2 4 -3 2 0 -3 -3 -2 -2 -2 2 0 0 0 0 0 0 0 0 0 7 78 0 0 0 0 0 0 0 0 14 0.56 0.09 487 Y -3 -3 -3 -4 -3 -2 -3 -4 1 -2 -2 -3 -2 3 -4 -3 -3 1 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 95 0 1.44 0.18 488 Q -1 0 -1 -1 -2 5 0 -2 -1 -2 -2 0 -1 -3 -2 1 4 -3 -2 -2 0 0 0 0 0 48 0 0 0 0 0 0 0 0 0 6 45 0 0 0 0.58 0.12 489 P -2 -3 -3 -2 -4 -2 -2 -3 -3 -4 -4 -2 -4 -5 8 -2 -2 -5 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.38 0.18 490 P -2 -3 -3 -2 -4 -2 -2 -3 -3 -4 -4 -2 -4 -5 8 -2 -2 -5 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.38 0.18 491 Q -1 3 2 -1 -2 2 -1 -2 -1 -2 -2 0 -2 -3 -2 0 4 -3 -2 -2 0 22 16 0 0 11 0 0 0 0 0 0 0 0 0 0 52 0 0 0 0.44 0.09 492 T 1 -3 -3 -3 6 -2 -3 -3 -2 1 -1 -2 -1 -1 -3 -1 1 -2 2 2 14 0 0 0 23 0 0 0 0 6 0 0 0 0 0 0 11 0 14 31 0.32 0.07 493 S 0 -2 0 -1 -2 -1 -1 -1 -2 -3 -3 -1 -2 -3 -2 6 1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.81 0.15 494 I -1 -3 -3 -4 -2 -3 -3 -4 -2 3 0 -3 0 0 -3 -2 -1 -1 4 4 0 0 0 0 0 0 0 0 0 30 0 0 0 0 0 0 0 0 25 44 0.45 0.09 495 T 0 -2 4 0 -2 -1 -1 2 -1 -3 -3 -1 -2 -3 -2 1 3 -3 -3 -2 7 0 31 0 0 0 0 21 0 0 0 0 0 0 0 10 31 0 0 0 0.41 0.07 496 S 0 -2 0 -1 -1 -1 -1 -1 -2 -1 -2 -1 -2 -3 -2 5 2 -4 -2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 72 14 0 0 14 0.47 0.11 497 A 2 -2 0 -1 -1 -1 -1 0 -2 -2 -2 -1 -2 -3 -1 3 4 -3 -2 -1 18 0 0 0 0 0 0 6 0 0 0 0 0 0 0 39 38 0 0 0 0.42 0.08 498 V 0 1 -3 -4 -2 -2 -3 -3 -2 1 3 -1 1 2 -3 -2 -1 -2 0 2 7 14 0 0 0 0 0 0 0 0 38 0 0 14 0 0 0 0 0 27 0.22 0.05 499 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.60 0.05 500 Q -1 1 0 -1 -4 7 2 -2 0 -3 -3 1 -1 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.93 0.09 K Lambda Standard Ungapped 0.1396 0.3268 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1396 0.3268 PSI Gapped 0.0410 0.2670