Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 M -1 -1 -2 -3 -1 0 -2 -3 -2 1 2 -1 6 0 -3 -2 -1 -1 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.34 0.00 2 N 0 -1 4 1 -2 0 0 0 0 -3 -3 0 -2 -3 -1 3 1 -3 -2 -2 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0.45 0.00 3 R -1 5 0 -1 -3 1 0 -2 0 -3 -2 3 -1 -3 -2 -1 -1 -3 -2 -2 0 74 0 0 0 0 0 0 0 0 0 26 0 0 0 0 0 0 0 0 0.63 0.00 4 H -1 -1 0 -1 -2 0 -1 -2 6 -2 -2 -1 -2 -2 4 0 1 -3 0 -2 0 0 0 0 0 0 0 0 50 0 0 0 0 0 25 0 24 0 0 0 0.58 0.00 5 L -1 -2 -2 -2 -2 -1 -1 -2 -2 -1 1 -1 -1 -2 7 -1 -1 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 25 0 0 0 75 0 0 0 0 0 1.33 0.00 6 W -3 -3 -4 -4 -2 -2 -3 -3 -2 -3 -2 -3 -1 1 -4 -3 -2 11 2 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 2.30 0.00 7 K -1 2 0 -1 -3 1 1 -2 -1 -3 -2 5 -1 -3 -1 0 -1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.51 0.00 8 S 1 -1 3 0 -1 0 0 0 0 -3 -3 0 -2 -3 -1 3 1 -3 -2 -2 0 0 26 0 0 0 0 0 0 0 0 0 0 0 0 74 0 0 0 0 0.41 0.00 9 Q -1 0 0 -1 -3 5 1 -2 0 -3 -2 1 -1 -3 4 0 -1 -2 -2 -2 0 0 0 0 0 75 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0.68 0.00 10 L -1 -2 -3 -3 -2 -2 -2 -3 -3 1 3 -2 1 0 4 -2 -1 -2 -1 0 0 0 0 0 0 0 0 0 0 0 76 0 0 0 24 0 0 0 0 0 0.47 0.00 11 C 0 -2 -1 -2 8 -2 -2 -2 -2 -2 -2 -2 -1 -2 -2 1 0 -2 -2 -1 0 0 0 0 74 0 0 0 0 0 0 0 0 0 0 26 0 0 0 0 0.80 0.00 12 E -1 0 0 2 -4 2 5 -2 0 -3 -3 1 -2 -3 -1 0 -1 -3 -2 -2 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.00 13 M -1 -1 -2 -3 -1 0 -2 -3 -2 1 2 -1 6 0 -3 -2 -1 -1 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.34 0.00 14 V 0 -3 -3 -3 -1 -2 -2 -3 -3 3 1 -2 1 -1 -2 -2 0 -3 -1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.34 0.00 15 Q -1 1 0 0 -3 5 2 -2 0 -3 -2 1 0 -3 -1 0 -1 -2 -1 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.65 0.00 16 P -1 -2 -2 -2 -3 -1 -1 -2 -2 -3 -3 -1 -3 -4 7 -1 -1 -4 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.04 0.00 17 S 1 -1 1 0 -1 0 0 0 -1 -2 -2 0 -2 -2 -1 4 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.45 0.00 18 G 0 -2 0 -1 -3 -2 -2 6 -2 -4 -4 -2 -3 -3 -2 0 -2 -3 -3 -3 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.04 0.00 19 G 0 -2 0 -1 -2 -1 -2 5 -2 -3 -3 -1 -2 -3 -2 1 -1 -3 -3 -3 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 25 0 0 0 0 0.73 0.00 20 P -1 -2 -2 -2 -3 -1 -1 -2 -2 -3 -3 -1 -3 -4 7 -1 -1 -4 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.04 0.00 21 A 4 -1 -2 -2 0 -1 -1 0 -2 -1 -1 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.40 0.00 22 A 2 -1 -1 0 -2 0 2 4 -1 -3 -3 -1 -2 -3 -2 0 -1 -3 -2 -2 25 0 0 0 0 0 26 50 0 0 0 0 0 0 0 0 0 0 0 0 0.46 0.01 23 D -2 -2 1 6 -4 0 2 -1 -1 -3 -4 -1 -3 -4 -2 0 -1 -4 -3 -3 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.92 0.00 24 Q -1 1 0 0 -3 5 2 -2 0 -3 -2 1 0 -3 -1 0 -1 -2 -1 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.65 0.00 25 D -2 -2 1 6 -4 0 2 -1 -1 -3 -4 -1 -3 -4 -2 0 -1 -4 -3 -3 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.92 0.00 26 V -1 -2 -3 -3 -1 -1 -2 -3 -2 2 1 -2 4 0 -2 -2 0 -2 -1 3 0 0 0 0 0 0 0 0 0 0 0 0 51 0 0 0 0 0 0 49 0.26 0.00 27 L -1 -2 -3 -4 -1 -2 -3 -4 -3 2 4 -2 2 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.00 28 G 0 -2 0 -1 -3 -2 -2 6 -2 -4 -4 -2 -3 -3 -2 0 -2 -3 -3 -3 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.04 0.00 29 E -1 0 0 2 -4 2 5 -2 0 -3 -3 1 -2 -3 -1 0 -1 -3 -2 -2 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.00 30 E -1 0 0 2 -4 2 5 -2 0 -3 -3 1 -2 -3 -1 0 -1 -3 -2 -2 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.00 31 S 1 -1 1 0 -1 0 0 0 -1 -2 -2 0 -2 -2 -1 4 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.45 0.00 32 P 1 -1 0 -1 -1 0 0 -1 -1 -2 -3 0 -2 -3 4 3 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 75 0 0 0 0 0.55 0.00 33 L -1 -2 -3 -4 -1 -2 -3 -4 -3 2 4 -2 2 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.00 34 G 0 -2 0 -1 -3 -2 -2 6 -2 -4 -4 -2 -3 -3 -2 0 -2 -3 -3 -3 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.04 0.00 35 K -1 2 0 -1 -3 1 1 -2 -1 -3 -2 5 -1 -3 -1 0 -1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.51 0.00 36 P -1 -2 -2 -2 -3 -1 -1 -2 -2 -3 -3 -1 -3 -4 7 -1 -1 -4 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.04 0.00 37 A 3 -1 -1 -2 -1 -1 -1 0 -2 -1 -1 -1 -1 -2 -1 1 2 -3 -2 0 76 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 24 0 0 0 0.32 0.00 38 M -1 -1 -2 -3 -1 0 -2 -3 -2 1 2 -1 6 0 -3 -2 -1 -1 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.34 0.00 39 L -1 -2 -3 -4 -1 -2 -3 -4 -3 2 4 -2 2 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.00 40 H -2 0 1 -1 -3 0 0 -2 8 -3 -3 -1 -2 -1 -2 -1 -2 -2 2 -3 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0.85 0.00 41 L -1 -2 -3 -4 -1 -2 -3 -4 -3 2 3 -2 2 0 -3 -2 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 0 25 0.37 0.01 42 P -1 -2 -2 -2 -3 -1 -1 -2 -2 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.06 0.01 43 S 1 -1 0 -1 -1 -1 -1 3 -1 -3 -3 -1 -2 -3 -1 3 1 -3 -2 -2 0 0 0 0 0 0 0 35 0 0 0 0 0 0 0 65 0 0 0 0 0.46 0.01 44 E -1 0 3 1 -3 1 4 -1 0 -3 -3 0 -2 -3 -1 0 -1 -3 -2 -3 0 0 35 0 0 0 65 0 0 0 0 0 0 0 0 0 0 0 0 0 0.57 0.01 45 Q -1 0 -1 -1 -2 4 1 -2 0 -1 2 0 1 -1 -2 -1 -1 -2 -1 -1 0 0 0 0 0 65 0 0 0 0 35 0 0 0 0 0 0 0 0 0 0.32 0.01 46 G 0 -2 0 -1 -3 -2 -2 6 -2 -4 -4 -2 -3 -3 -2 0 -2 -3 -3 -3 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.06 0.01 47 A 2 -1 0 -1 -1 -1 -1 -1 -1 -1 -2 -1 -1 -2 -1 3 3 -3 -2 -1 32 0 0 0 0 0 0 0 0 0 0 0 0 0 0 35 33 0 0 0 0.32 0.00 48 P -1 -1 -1 0 -3 0 3 -2 -1 -3 -3 0 -2 -4 6 -1 -1 -3 -3 -2 0 0 0 0 0 0 35 0 0 0 0 0 0 0 65 0 0 0 0 0 1.26 0.01 49 E -1 0 0 1 -4 2 5 -2 0 -3 -3 1 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.76 0.01 50 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 1 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.50 0.01 51 L -2 -2 -3 -4 -2 -2 -3 -4 -2 1 3 -3 1 4 -3 -2 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 67 0 0 33 0 0 0 0 0 0 0.41 0.00 52 Q -1 1 0 0 -3 6 2 -2 0 -3 -2 1 0 -3 -1 0 -1 -2 -2 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.69 0.01 53 R -1 5 0 -1 -3 3 1 -2 0 -3 -2 2 -1 -3 -2 -1 -1 -2 -2 -2 0 65 0 0 0 35 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.61 0.01 54 C -1 -3 -3 -4 8 -3 -3 -3 -3 0 2 -3 0 -1 -3 -1 -1 -2 -2 0 0 0 0 0 65 0 0 0 0 0 35 0 0 0 0 0 0 0 0 0 0.73 0.01 55 L -1 -2 -3 -3 -1 -2 -3 -4 -3 3 3 -3 2 0 -3 -2 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 35 65 0 0 0 0 0 0 0 0 0 0.39 0.00 56 E -1 1 0 1 -3 2 4 -2 0 -3 -3 3 -2 -3 -1 0 -1 -3 -2 -2 0 0 0 0 0 0 65 0 0 0 0 35 0 0 0 0 0 0 0 0 0.56 0.01 57 E -1 0 0 1 -4 2 5 -2 0 -3 -3 1 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.76 0.01 58 N -2 -1 6 1 -3 0 0 0 1 -3 -3 0 -2 -3 -2 1 0 -4 -2 -3 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.76 0.01 59 Q -1 3 0 -1 -3 5 1 -2 0 -3 -2 2 -1 -3 -2 0 -1 -2 -2 -2 0 35 0 0 0 65 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.58 0.01 60 E -1 -1 0 4 -4 1 4 -2 0 -3 -3 0 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 35 0 0 65 0 0 0 0 0 0 0 0 0 0 0 0 0 0.68 0.01 61 L -2 -2 -3 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.47 0.01 62 R -1 5 0 -1 -3 1 0 -2 0 -3 -2 3 -1 -3 -2 -1 -1 -3 -2 -2 0 65 0 0 0 0 0 0 0 0 0 35 0 0 0 0 0 0 0 0 0.61 0.01 63 D -1 -1 1 5 -4 1 3 -2 -1 -3 -3 0 -3 -3 -1 0 -1 -4 -3 -3 0 0 0 65 0 0 35 0 0 0 0 0 0 0 0 0 0 0 0 0 0.74 0.01 64 A 4 -1 -2 -2 0 -1 -1 0 -2 -1 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.42 0.01 65 I -1 -3 -3 -3 -1 -3 -3 -4 -3 3 3 -3 1 0 -3 -2 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 65 35 0 0 0 0 0 0 0 0 0 0.37 0.01 66 R -1 5 0 -1 -3 1 0 -2 0 -3 -2 3 -1 -3 -2 -1 -1 -3 -2 -2 0 65 0 0 0 0 0 0 0 0 0 35 0 0 0 0 0 0 0 0 0.61 0.01 67 Q -1 1 0 0 -3 6 2 -2 0 -3 -2 1 0 -3 -1 0 -1 -2 -2 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.69 0.01 68 S 1 -1 0 -1 -1 0 0 -1 -1 -2 -2 0 -1 -2 -1 3 3 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 65 35 0 0 0 0.40 0.01 69 N -2 -1 6 1 -3 0 0 0 1 -3 -3 0 -2 -3 -2 1 0 -4 -2 -3 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.76 0.01 70 Q -1 0 -1 -1 -2 4 1 -2 0 -1 2 0 1 -1 -2 -1 -1 -2 -1 -1 0 0 0 0 0 65 0 0 0 0 35 0 0 0 0 0 0 0 0 0 0.32 0.01 71 I 0 -1 -1 -2 -1 -1 -1 -2 -2 1 1 -1 4 -1 -2 2 0 -2 -1 1 0 0 0 0 0 0 0 0 0 16 0 0 49 0 0 35 0 0 0 0 0.16 0.01 72 L -1 -2 -3 -3 -1 -1 -3 -3 -2 1 3 -2 4 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 65 0 35 0 0 0 0 0 0 0 0.38 0.01 73 R -1 5 0 -1 -3 1 0 -2 0 -3 -2 3 -1 -3 -2 -1 -1 -3 -2 -2 0 65 0 0 0 0 0 0 0 0 0 35 0 0 0 0 0 0 0 0 0.61 0.01 74 E -1 0 0 1 -4 2 5 -2 0 -3 -3 1 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.76 0.01 75 R -1 6 -1 -2 -3 1 0 -2 0 -3 -2 2 -1 -3 -2 -1 -1 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.78 0.01 76 C -1 -3 -3 -4 8 -3 -4 -3 -2 -1 -1 -3 -1 3 -3 -1 -1 -1 1 -1 0 0 0 0 65 0 0 0 0 0 0 0 0 35 0 0 0 0 0 0 0.78 0.01 77 E -1 0 0 1 -4 2 5 -2 0 -3 -3 1 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.76 0.01 78 E -1 -1 0 1 -3 1 4 3 -1 -3 -3 0 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 65 35 0 0 0 0 0 0 0 0 0 0 0 0 0.54 0.01 79 L -2 -2 -3 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.47 0.01 80 L 0 0 0 -1 -2 3 0 -2 -1 -1 1 0 0 -1 -2 2 0 -2 -1 -1 0 0 0 0 0 33 0 0 0 0 32 0 0 0 0 35 0 0 0 0 0.18 0.00 81 H 2 2 0 -1 -2 0 0 -1 6 -2 -2 0 -1 -2 -2 0 -1 -3 0 -2 35 16 0 0 0 0 0 0 49 0 0 0 0 0 0 0 0 0 0 0 0.38 0.01 82 F -2 -3 -3 -4 -2 -3 -3 -3 -2 -1 0 -3 0 5 -4 -3 -2 8 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 65 0 0 0 35 0 0 1.02 0.01 83 Q -1 1 0 0 -3 5 1 -2 0 -3 -2 3 -1 -3 -1 0 -1 -2 -2 -2 0 0 0 0 0 65 0 0 0 0 0 35 0 0 0 0 0 0 0 0 0.54 0.01 84 A 1 -1 -1 0 -2 0 2 3 -1 -1 -2 0 -1 -3 -2 0 -1 -3 -2 0 16 0 0 0 0 0 35 33 0 0 0 0 0 0 0 0 0 0 0 16 0.27 0.00 85 S 0 1 2 0 -2 0 0 -1 -1 -3 -3 2 -2 -3 -1 3 1 -3 -2 -2 0 0 17 0 0 0 0 0 0 0 0 35 0 0 0 48 0 0 0 0 0.33 0.00 86 Q -1 1 0 0 -3 6 2 -2 0 -3 -2 1 0 -3 -1 0 -1 -2 -2 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.69 0.01 87 R -1 5 0 -1 -3 1 0 -2 0 -3 -2 3 -1 -3 -2 -1 -1 -3 -2 -2 0 65 0 0 0 0 0 0 0 0 0 35 0 0 0 0 0 0 0 0 0.61 0.01 88 E -1 0 0 1 -4 2 5 -2 0 -3 -3 1 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.76 0.01 89 E -1 0 0 1 -4 2 5 -2 0 -3 -3 1 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.76 0.01 90 K -1 4 0 -1 -3 1 0 -2 -1 -3 -2 4 -1 -3 -1 0 -1 -3 -2 -2 0 35 0 0 0 0 0 0 0 0 0 65 0 0 0 0 0 0 0 0 0.54 0.01 91 E 1 -1 0 4 -3 1 4 -1 -1 -3 -3 0 -2 -3 -1 0 -1 -3 -2 -2 17 0 0 35 0 0 48 0 0 0 0 0 0 0 0 0 0 0 0 0 0.51 0.00 92 F -2 -3 -3 -4 -2 -3 -3 -3 -1 0 0 -3 0 6 -4 -2 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.78 0.01 93 L -2 -2 -3 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.47 0.01 94 M -1 -1 -1 -1 -2 1 2 -3 -1 0 1 0 5 -1 -2 -1 -1 -2 -1 0 0 0 0 0 0 0 35 0 0 0 0 0 65 0 0 0 0 0 0 0 0.25 0.01 95 C -1 0 -1 -1 6 4 1 -2 0 -2 -2 0 -1 -3 -2 0 -1 -2 -2 -2 0 0 0 0 32 68 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.54 0.01 96 K -1 4 0 -1 -3 1 0 -2 -1 -3 -2 4 -1 -3 -1 0 -1 -3 -2 -2 0 35 0 0 0 0 0 0 0 0 0 65 0 0 0 0 0 0 0 0 0.54 0.01 97 F -2 -3 -3 -4 -2 -3 -3 -3 -2 1 2 -3 1 5 -3 -2 -2 0 2 0 0 0 0 0 0 0 0 0 0 0 35 0 0 65 0 0 0 0 0 0 0.51 0.01 98 Q -1 0 0 0 4 4 3 -2 0 -3 -2 1 -1 -3 -1 0 -1 -2 -2 -2 0 0 0 0 16 49 35 0 0 0 0 0 0 0 0 0 0 0 0 0 0.48 0.01 99 E -1 0 0 1 -4 2 5 -2 0 -3 -3 1 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.82 0.03 100 A 4 -2 -1 -2 -1 -1 -1 3 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 -1 74 0 0 0 0 0 0 26 0 0 0 0 0 0 0 0 0 0 0 0 0.44 0.02 101 R -2 5 -1 -2 -3 0 -1 -3 -1 1 -1 1 -1 -2 -2 -1 -1 -3 -2 0 0 74 0 0 0 0 0 0 0 26 0 0 0 0 0 0 0 0 0 0 0.46 0.03 102 K -1 2 0 2 -3 1 2 -2 -1 -2 -2 2 -2 -3 -1 0 2 -3 -2 -2 0 11 0 14 0 0 26 0 0 0 0 23 0 0 0 0 25 0 0 0 0.33 0.01 103 L -2 2 -2 -3 -2 -1 -2 -3 -2 1 3 -1 1 0 -3 -2 -1 -2 -1 0 0 25 0 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 0 0 0.32 0.02 104 V -1 -3 -3 -3 -1 -3 -3 -3 -3 2 2 -3 1 3 -3 -2 -1 -1 1 3 0 0 0 0 0 0 0 0 0 0 25 0 0 26 0 0 0 0 0 48 0.30 0.02 105 E -1 -1 3 1 -3 1 4 -2 0 -2 -2 0 -2 -3 -2 0 -1 -3 -2 0 0 0 25 0 0 0 61 0 0 0 0 0 0 0 0 0 0 0 0 14 0.43 0.02 106 R -1 4 3 -1 -2 0 0 -2 0 -2 -2 1 -1 -3 -2 0 2 -3 -2 -2 0 48 26 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0 0.41 0.02 107 L -1 -2 -1 2 -2 -1 -1 -3 -2 1 3 -2 3 0 -2 -2 -1 -2 -2 0 0 0 0 26 0 0 0 0 0 0 48 0 25 0 0 0 0 0 0 0 0.25 0.02 108 G 0 -1 1 3 -2 0 0 1 -1 -3 -3 -1 -2 -3 -1 3 1 -3 -2 -2 0 0 0 25 0 0 0 12 0 0 0 0 0 0 0 62 0 0 0 0 0.41 0.02 109 L -1 -2 -2 -1 -2 -1 2 -3 -2 1 2 -1 1 -1 -2 -2 -1 -2 -1 2 0 0 0 0 0 0 26 0 0 0 48 0 0 0 0 0 0 0 0 25 0.20 0.01 110 E -1 0 0 1 -4 2 5 -2 0 -3 -3 1 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.82 0.03 111 K -1 1 3 -1 -2 0 0 -2 -1 -1 1 3 0 -2 -2 0 -1 -3 -2 -1 0 0 25 0 0 0 0 0 0 0 26 48 0 0 0 0 0 0 0 0 0.22 0.02 112 L 0 1 -1 -1 -2 0 2 -2 -1 -1 1 0 0 -1 -2 1 0 -2 -2 -1 0 14 0 0 0 0 25 0 0 0 35 0 0 0 0 26 0 0 0 0 0.15 0.01 113 D 1 -1 0 4 -2 0 3 -1 -1 -3 -3 0 -2 -3 -1 0 -1 -3 -3 -2 25 0 0 50 0 0 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0.50 0.02 114 L -2 -2 -4 -4 -1 -2 -3 -4 -3 1 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.51 0.03 115 K -1 4 3 0 -3 1 0 -2 0 -3 -3 3 -2 -3 -2 0 -1 -3 -2 -3 0 36 26 0 0 0 0 0 0 0 0 38 0 0 0 0 0 0 0 0 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S 0 1 1 -1 -2 2 0 1 -1 -2 -2 0 -1 -1 -1 1 0 5 -1 -2 2 12 9 1 0 14 1 14 0 1 2 1 0 1 1 22 1 13 1 1 0.24 0.01 384 Q -1 0 0 1 -3 5 1 1 0 -3 -2 1 -1 -3 -1 0 -1 -2 -2 -2 1 1 1 12 0 63 1 14 0 1 1 1 0 1 1 1 1 0 0 1 0.45 0.04 385 R -2 5 -1 -2 -3 1 0 -3 3 -3 -2 1 -2 -2 -2 -1 -2 5 -1 -3 0 69 0 0 0 7 0 0 12 0 0 0 0 0 0 0 0 11 0 0 0.69 0.05 386 R -1 3 1 -1 -3 1 -1 4 -1 -4 -3 1 -2 -3 -2 -1 -1 -3 -2 -3 0 39 6 0 0 7 0 47 0 0 0 0 0 0 0 0 0 0 0 0 0.55 0.04 387 S 1 0 1 0 -2 3 2 -1 -1 -1 -2 0 -1 -3 -1 2 1 -3 -2 -1 13 0 7 0 0 24 13 0 0 6 0 0 0 0 0 28 9 0 0 0 0.25 0.02 388 P 1 -1 -1 -1 -2 1 -1 1 -1 -2 -2 -1 -1 -2 5 0 -1 5 -1 -2 15 1 1 1 0 13 1 11 0 1 2 1 0 1 35 1 1 13 1 1 0.59 0.02 389 P -1 -1 1 -1 -2 2 0 -2 -1 -1 -2 0 -1 -3 5 0 -1 -3 -2 -2 1 0 13 0 0 24 0 1 0 7 1 0 0 0 41 10 0 0 0 0 0.66 0.03 390 E -1 3 0 1 -3 3 2 -2 0 -2 -1 1 1 -2 -1 0 -1 -2 -2 -2 1 24 1 7 0 23 22 1 0 1 1 1 13 1 1 1 1 0 0 1 0.29 0.02 391 E -1 0 2 1 -2 2 4 -1 0 -3 -2 0 -2 -3 -1 1 0 -2 -2 -2 1 1 12 1 0 13 51 1 0 1 1 1 0 1 1 13 1 0 0 1 0.42 0.03 392 P -1 -1 1 -1 -2 1 -1 -2 -1 2 -1 -1 -1 -1 4 -1 -1 4 -1 0 0 0 13 0 0 13 0 0 0 31 1 0 0 0 28 0 0 9 0 0 0.39 0.03 393 P -1 -2 -2 -2 -3 -1 -1 -2 -2 -3 -3 -1 -3 -4 7 -1 -1 -4 -3 -2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 94 0 0 0 0 0 1.99 0.07 394 D -1 -1 1 3 -2 0 1 -2 -1 1 -1 0 -1 -2 -2 1 0 -3 -2 0 0 0 7 28 0 0 10 0 0 31 1 7 0 0 0 14 0 0 0 0 0.16 0.02 395 F -2 -1 -1 -2 -3 -1 -1 -3 6 -2 -1 -2 -1 4 -3 -2 -2 0 4 -2 0 0 0 0 0 0 0 0 50 0 0 0 0 28 0 0 0 0 22 0 0.69 0.05 396 C 1 -2 -1 -1 6 -1 -1 -1 -2 -2 -2 -1 -1 -3 -1 3 2 -3 -2 -1 13 0 0 0 28 0 0 0 0 0 0 0 0 0 0 46 13 0 0 0 0.44 0.04 397 C -1 -4 -3 -4 9 -3 -4 -3 -3 -2 -2 -3 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.64 0.09 398 P -1 -3 -2 -2 -3 -2 -1 -3 -3 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.20 0.08 399 K -1 2 0 -1 -3 1 0 -2 -1 -3 -3 5 -2 -3 -1 -1 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.70 0.07 400 C -1 -4 -3 -4 9 -3 -4 -3 -3 -2 -2 -3 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.64 0.09 401 Q -1 -1 2 0 -3 3 1 4 -1 -4 -3 0 -2 -3 -2 0 -1 -3 -2 -3 0 0 13 0 0 28 9 50 0 0 0 0 0 0 0 0 0 0 0 0 0.54 0.04 402 Y -1 -1 -1 0 -3 1 4 -3 0 -2 0 0 -1 0 -2 -1 -1 -1 4 -2 0 0 0 0 0 0 59 0 0 0 13 0 0 0 0 0 0 0 28 0 0.43 0.04 403 Q -1 -1 -2 -2 -2 3 -1 -3 -2 2 0 -1 0 -2 -2 -1 1 -3 -2 3 0 0 0 0 0 28 0 0 0 9 0 0 0 0 0 0 13 0 0 50 0.22 0.03 404 A 2 -2 -3 -3 -1 -2 -2 -2 -3 1 3 -2 1 0 -2 -1 -1 -2 -1 1 28 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 13 0.26 0.03 405 P -1 -3 -2 -2 -3 -2 -1 -3 -3 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.20 0.08 406 D -2 -2 1 6 -4 -1 1 -2 -1 -3 -4 -1 -3 -4 -2 -1 -1 -5 -3 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.07 407 M -1 -2 -3 -3 -2 -2 -3 -4 -3 3 2 -2 4 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 44 22 0 34 0 0 0 0 0 0 0 0.39 0.04 408 D -2 -2 1 6 -4 -1 1 -2 -1 -3 -4 -1 -3 -4 -2 -1 -1 -5 -3 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.07 409 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -2 -1 -1 -2 -1 2 5 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 87 0 0 0 0.58 0.06 410 L -2 -2 -4 -4 -2 -2 -3 -4 -3 1 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.58 0.05 411 Q -1 1 0 -1 -3 6 1 -2 0 -3 -1 1 -1 -3 -2 -1 -1 -2 -2 -2 0 0 0 0 0 93 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0.76 0.07 412 I -2 -3 -4 -3 -2 -3 -4 -4 -4 5 1 -3 1 0 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0.57 0.06 413 H -2 -1 0 -2 -3 0 -1 -2 8 -4 -3 -1 -2 -2 -3 -1 -2 -3 1 -4 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 1.26 0.09 414 V -1 -3 -3 -3 -1 -3 -3 -3 -3 3 1 -3 1 -1 -3 -2 0 -3 -1 4 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 87 0.47 0.05 415 M -1 -2 -2 -3 -2 -1 -2 -3 -2 1 1 -2 7 0 -3 -2 0 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 93 0 0 0 7 0 0 0 0.62 0.08 416 E -2 -1 1 5 -4 0 3 -2 -1 -3 -4 0 -3 -4 -2 0 -1 -4 -3 -3 0 0 0 72 0 0 28 0 0 0 0 0 0 0 0 0 0 0 0 0 0.87 0.05 417 C -1 -4 -3 -4 9 -3 -4 -3 -3 -2 -2 -3 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.64 0.09 418 I -2 -3 -4 -3 -2 -3 -4 -4 -4 5 1 -3 1 0 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0.57 0.06 419 E -1 0 0 2 -4 2 5 -2 0 -3 -3 1 -2 -3 -1 0 -1 -3 -2 -2 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.00 K Lambda Standard Ungapped 0.1261 0.3127 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1261 0.3127 PSI Gapped 0.0410 0.2670