Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 M -1 -2 -3 -4 -2 0 -2 -3 -2 1 2 -2 6 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.33 0.00 2 N -2 -1 5 0 -2 -1 -1 -1 0 2 -1 -1 -1 -2 -3 0 0 -4 -2 0 0 0 65 0 0 0 0 0 0 35 0 0 0 0 0 0 0 0 0 0 0.30 0.01 3 E -1 0 0 2 -4 2 6 -2 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.00 4 L -2 -3 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.01 5 T 0 -1 0 -1 -1 -1 -1 -1 -2 -1 -2 -1 -1 -3 -1 3 4 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 35 65 0 0 0 0.39 0.01 6 L -2 -3 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.01 7 I -2 -3 -4 -4 -1 -3 -4 -4 -4 5 2 -3 1 0 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0.38 0.01 8 D -2 -2 1 7 -4 0 2 -2 -1 -4 -4 -1 -4 -4 -2 0 -1 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.92 0.00 9 F -3 -3 -4 -4 -3 -4 -4 -4 -1 0 0 -4 0 7 -4 -3 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.73 0.00 10 Y -2 -2 -2 -4 -3 -2 -2 -4 2 -2 -1 -2 -1 3 -3 -2 -2 3 8 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0.85 0.00 11 L -2 -3 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.01 12 C 0 -4 -3 -4 10 -3 -4 -3 -3 -1 -1 -4 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.19 0.00 13 F -3 -3 -4 -4 -3 -4 -4 -4 -1 0 0 -4 0 7 -4 -3 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.73 0.00 14 L -2 -3 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.01 15 A 5 -2 -2 -2 0 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.40 0.01 16 F -3 -3 -4 -4 -3 -4 -4 -4 -1 0 0 -4 0 7 -4 -3 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.73 0.00 17 L -2 -3 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.01 18 L -2 -3 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.01 19 F -3 -3 -4 -4 -3 -4 -4 -4 -1 0 0 -4 0 7 -4 -3 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.73 0.00 20 L -2 -3 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.01 21 V 0 -3 -3 -4 -1 -3 -3 -4 -4 3 1 -3 1 -1 -3 -2 0 -3 -1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.34 0.01 22 L -2 -3 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.01 23 I -2 -3 -4 -4 -1 -3 -4 -4 -4 5 2 -3 1 0 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0.38 0.01 24 M -1 -2 -3 -4 -2 0 -2 -3 -2 1 2 -2 6 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.33 0.00 25 L -2 -3 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.01 26 I -2 -3 -4 -4 -1 -3 -4 -4 -4 5 2 -3 1 0 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0.38 0.01 27 I -2 -3 -4 -4 -1 -3 -4 -4 -4 5 2 -3 1 0 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0.38 0.01 28 F -3 -3 -4 -4 -3 -4 -4 -4 -1 0 0 -4 0 7 -4 -3 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.73 0.00 29 W -3 -3 -4 -5 -3 -2 -3 -3 -3 -3 -2 -3 -2 1 -4 -3 -3 12 3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 2.29 0.00 30 F -3 -3 -4 -4 -3 -4 -4 -4 -1 0 0 -4 0 7 -4 -3 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.73 0.00 31 S 1 -1 1 0 -1 0 0 0 -1 -3 -3 0 -2 -3 -1 5 2 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.45 0.00 32 L -2 -3 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.01 33 E -1 0 0 2 -4 2 6 -2 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.00 34 I -2 -3 -4 -4 -1 -3 -3 -4 -3 3 4 -3 2 0 -3 -3 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 33 67 0 0 0 0 0 0 0 0 0 0.38 0.01 35 Q -1 1 0 0 -3 6 2 -2 1 -3 -2 1 0 -4 -1 0 -1 -2 -2 -3 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.64 0.00 36 D -2 -2 1 7 -4 0 2 -2 -1 -4 -4 -1 -4 -4 -2 0 -1 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.92 0.00 37 L -2 -2 -2 -3 -2 -1 -2 -4 5 2 2 -2 1 0 -3 -2 -1 -3 0 1 0 0 0 0 0 0 0 0 35 32 33 0 0 0 0 0 0 0 0 0 0.24 0.01 38 E -1 0 4 2 -4 2 5 -2 0 -4 -4 1 -2 -4 -2 0 -1 -4 -2 -3 0 0 35 0 0 0 65 0 0 0 0 0 0 0 0 0 0 0 0 0 0.56 0.01 39 E -1 0 0 2 -4 2 6 -2 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.00 40 P -1 -2 -1 -2 -2 -1 -1 -2 -2 -2 -3 -1 -2 -3 7 0 3 -4 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 65 0 35 0 0 0 1.19 0.01 41 C 0 -4 -3 -4 10 -3 -4 -3 -3 -1 -1 -4 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.19 0.00 42 T -1 -1 5 0 -2 0 -1 -1 0 -2 -2 0 -2 -3 -2 1 4 -3 -2 -1 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 0.41 0.00 43 K -1 2 0 -1 -4 1 1 -2 -1 -3 -3 5 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.51 0.00 44 V 0 -3 -3 -4 -1 -3 -3 -4 -4 3 1 -3 1 -1 -3 -2 0 -3 -1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.34 0.00 K Lambda Standard Ungapped 0.1552 0.3419 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1552 0.3419 PSI Gapped 0.0410 0.2670