Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 M -1 -2 -2 -3 -2 -1 -2 -3 -2 1 2 -2 7 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.45 0.03 2 A 4 -2 -1 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 2 0 -3 -2 -1 83 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0.45 0.04 3 V 2 -2 -3 -3 -1 -2 -2 -2 -3 2 0 -2 0 -1 -2 -1 0 -3 -2 3 33 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 50 0.26 0.03 4 F -1 -1 -2 -2 -2 -1 -2 -2 -2 -1 1 1 0 4 -2 1 -1 -1 1 -1 0 0 0 0 0 0 0 0 0 0 19 14 0 42 0 25 0 0 0 0 0.23 0.04 5 K 0 3 -1 -1 -3 3 2 -2 -1 -3 -3 3 -1 -3 -2 0 -1 -3 -2 -2 12 19 0 0 0 21 16 0 0 0 0 32 0 0 0 0 0 0 0 0 0.42 0.05 6 T 1 -2 -1 2 -1 -1 -1 -2 -2 1 0 -1 0 -2 -2 2 3 -3 -2 0 13 0 0 14 0 0 0 0 0 11 12 0 0 0 0 16 33 0 0 0 0.19 0.05 7 T 0 -1 -1 -2 -2 -1 -1 -2 -2 0 0 1 -1 -2 -2 0 4 -3 -2 1 6 0 0 0 0 0 0 0 0 0 9 11 0 0 0 0 62 0 0 12 0.35 0.09 8 L 0 0 -2 -3 -2 -2 -2 -3 -3 2 2 -1 1 -1 -2 -1 2 -3 -2 2 5 9 0 0 0 0 0 0 0 9 34 0 0 0 0 0 24 0 0 20 0.21 0.06 9 W -1 -5 -5 -6 -4 -4 -5 -4 -4 -4 -4 -5 -3 -1 -5 -4 0 12 0 -4 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 88 0 0 3.22 0.48 10 R -2 5 -1 -2 -4 2 -1 -3 4 -4 -3 3 1 -4 -3 0 -2 -4 -2 -4 0 48 2 0 0 8 0 0 16 0 0 16 5 0 0 5 0 0 0 0 0.80 0.26 11 L -2 1 -4 -4 -3 -3 -3 -4 -3 1 4 -3 4 0 -4 -2 -2 -3 -2 1 0 10 0 0 0 0 0 0 0 3 62 0 13 3 0 3 0 0 0 5 0.61 0.23 12 I -2 -3 -3 -4 -2 -1 -3 -4 -3 5 2 -3 2 -1 -3 -2 1 -3 -2 2 0 0 0 0 0 4 0 0 0 48 18 0 4 0 0 0 9 0 0 14 0.51 0.20 13 S 3 -2 -2 -2 -2 -2 -2 -2 -3 1 -1 -2 -1 -3 0 2 1 -3 -2 1 38 0 0 0 0 0 0 0 0 8 5 0 0 0 4 22 11 0 0 8 0.32 0.17 14 G 0 -2 -2 -2 2 -1 0 2 -3 1 0 0 1 -2 -3 0 -1 -3 -3 1 4 0 0 0 6 0 7 22 0 6 10 10 5 0 0 11 0 0 0 19 0.15 0.11 15 T 1 -2 -2 -3 1 -2 -2 0 -3 2 -1 0 1 0 0 -1 1 -3 -2 2 15 0 0 0 4 0 0 8 0 18 0 10 4 5 4 0 10 0 0 24 0.16 0.13 16 L -3 -4 -4 -5 -3 -3 -4 -2 -4 1 5 -4 2 1 -4 -2 -2 3 -2 0 0 0 0 0 0 0 0 4 0 5 71 0 5 4 0 4 0 4 0 4 0.72 0.27 17 G 1 -4 -2 -3 -4 -3 -4 6 -4 0 -4 -3 -3 -1 -4 -1 -1 -4 -4 -3 10 0 0 0 0 0 0 72 0 8 0 0 0 3 0 4 3 0 0 0 1.13 0.34 18 I -1 -4 -4 -4 3 -4 -4 -5 -5 6 0 -2 -1 -2 -4 -3 0 -4 -3 3 5 0 0 0 8 0 0 0 0 57 2 4 0 0 0 0 5 0 0 19 0.76 0.30 19 I -1 -2 -4 -4 -3 -3 -4 -5 -4 5 3 -2 1 0 -4 -2 -2 -4 -2 2 4 2 0 0 0 0 0 0 0 41 33 3 3 2 0 2 0 0 0 9 0.58 0.24 20 C -1 -5 -5 -5 9 -5 -5 -2 -5 0 1 -5 -2 -1 -5 -1 -3 -4 -4 1 3 0 0 0 60 0 0 3 0 5 15 0 0 2 0 3 0 0 0 9 1.54 0.44 21 L -2 -4 -5 -5 1 -4 -4 -5 -4 2 4 -4 0 3 -4 -3 -1 -3 -2 2 3 0 0 0 3 0 0 0 0 13 53 0 0 12 0 0 2 0 0 15 0.65 0.26 22 S 0 0 -3 -3 -2 -1 -2 -2 -3 3 1 0 0 0 -3 0 -1 -3 -2 3 6 4 0 0 0 3 0 3 0 19 10 8 2 3 0 9 0 0 0 32 0.23 0.16 23 L -3 -4 -5 -5 -3 -4 -5 -5 -5 3 5 -4 2 -1 -5 -4 -1 -4 -3 2 0 0 0 0 0 0 0 0 0 19 64 0 5 0 0 0 2 0 0 10 0.89 0.32 24 M -3 -2 -4 -5 1 -3 -4 -5 -3 2 3 -3 6 1 -4 -3 -2 -3 1 2 0 3 0 0 3 0 0 0 0 12 25 0 31 6 0 0 0 0 5 16 0.67 0.29 25 S 2 -3 -2 -3 2 -2 -2 0 -3 1 -1 -1 0 0 -3 1 2 -3 -2 2 20 0 0 0 5 0 0 6 0 6 0 4 3 6 0 15 15 0 0 21 0.22 0.17 26 T 0 -2 1 -2 0 -2 -2 0 -2 1 -1 0 1 -2 -3 1 4 -3 0 1 6 0 7 0 2 0 0 7 0 9 4 5 4 0 0 7 35 0 4 10 0.24 0.18 27 L -1 -3 -3 -4 -2 -3 -3 -4 -3 1 2 -3 4 -1 -4 0 1 1 0 3 4 0 0 0 0 0 0 0 0 5 25 0 16 0 0 7 9 2 4 27 0.41 0.23 28 G 1 -3 0 -2 -3 -2 -2 4 -3 -1 -3 -2 0 -1 -2 2 -1 -3 -3 1 10 0 5 0 0 0 0 34 0 3 1 2 3 3 1 24 0 0 0 12 0.39 0.21 29 I 0 -3 -3 -4 -2 -3 -3 -4 -4 4 0 -3 1 2 -3 -1 0 -3 -2 4 7 0 0 0 0 0 0 0 0 30 4 0 4 11 0 3 6 0 0 32 0.47 0.23 30 L -1 -3 -4 -4 -3 -3 -4 -2 -4 3 4 -2 2 -1 -4 -3 -2 1 -2 2 3 0 0 0 0 0 0 4 0 21 45 3 6 0 0 0 0 3 0 13 0.53 0.24 31 L -1 -1 -3 -4 1 -1 -2 -4 -3 2 3 -3 4 0 -3 -2 -1 -3 -2 2 6 4 0 0 3 4 2 0 0 9 36 0 14 4 0 0 3 0 0 15 0.36 0.20 32 K -1 1 0 -2 0 1 -1 0 -2 -1 -2 2 -2 -3 3 0 0 1 -2 0 2 8 6 0 2 8 2 6 0 2 3 20 0 0 17 5 5 2 0 10 0.24 0.14 33 N 0 0 3 0 -2 0 0 -2 2 -1 0 1 -1 -1 -2 1 0 -3 -2 0 5 3 20 5 0 3 4 1 7 3 13 9 0 3 0 11 3 0 0 9 0.12 0.11 34 S 0 -2 0 -2 0 -2 -1 -1 1 -1 1 -2 -1 -1 -2 2 2 1 -2 -1 6 0 4 0 2 0 4 4 4 3 22 0 0 2 1 24 19 2 0 2 0.20 0.18 35 F -1 -2 -3 -2 0 -3 -3 -4 2 2 0 -3 -1 5 -3 -2 -1 -2 1 3 4 3 0 2 3 0 0 0 6 12 7 0 0 28 0 3 2 0 4 25 0.39 0.21 36 T 1 -2 0 -1 -2 1 0 -1 -2 0 -1 -2 -1 -1 -1 1 3 -3 -1 1 11 0 5 2 0 7 6 5 0 4 6 0 0 3 2 12 24 0 2 10 0.15 0.14 37 K 0 2 -1 -2 2 2 0 -2 -2 0 -1 3 -2 -3 0 -1 0 -4 -3 0 6 9 1 0 6 9 4 3 0 5 4 30 0 0 3 2 7 0 0 10 0.24 0.17 38 L -2 -1 -1 -3 2 0 0 -2 -3 1 3 -2 0 -1 1 0 -1 -3 -2 1 0 3 2 0 5 6 6 3 0 7 35 1 0 2 8 7 3 0 0 10 0.18 0.15 39 S 1 0 2 -1 2 0 1 -2 -1 -3 -1 -1 -2 -3 0 3 0 1 -2 -2 15 4 11 0 6 4 9 1 1 0 8 2 0 0 5 27 2 2 0 1 0.24 0.17 40 I -2 0 -2 -3 -2 0 -1 -3 -2 2 2 -1 2 1 -2 -1 1 -2 -1 2 1 5 1 0 0 4 5 1 0 15 24 3 6 7 1 4 9 0 0 14 0.16 0.12 41 E -2 0 -1 0 -3 3 4 -2 0 -2 -1 0 -2 -3 -2 1 -1 -3 -1 -3 1 5 2 4 0 19 33 3 2 3 6 4 0 0 1 13 2 0 3 1 0.42 0.23 42 P -1 1 0 -1 -3 0 -1 -3 -2 0 -1 1 -2 -3 5 0 -1 -3 -1 0 3 9 5 4 0 3 3 1 0 5 7 11 0 0 28 8 1 0 2 10 0.37 0.16 43 A 1 -1 -1 -2 1 1 0 -1 -1 -2 0 0 -1 -2 1 1 2 -3 0 0 16 2 0 0 4 9 4 2 2 0 10 5 0 0 5 15 13 0 4 6 0.13 0.12 44 F -1 -1 0 -2 -3 0 0 -3 -1 0 1 -1 -1 2 0 -1 -1 3 3 0 3 2 6 0 0 5 5 1 0 3 21 2 0 10 5 5 2 4 15 9 0.16 0.12 45 T -1 -1 1 -2 2 0 -2 -2 0 -1 0 -1 -1 0 0 3 1 -3 -2 1 3 3 8 0 5 6 1 1 2 2 8 3 0 4 4 29 10 0 0 12 0.18 0.16 46 P 0 0 0 -1 0 0 0 -2 0 -1 0 0 -2 -3 5 0 -1 -3 -3 0 8 4 5 2 2 5 4 1 2 2 9 5 0 1 31 8 2 0 0 7 0.41 0.16 47 G 0 1 1 0 -2 0 1 2 -1 -2 -2 1 -1 -3 -2 1 1 -3 -2 -2 5 7 6 3 0 2 10 18 0 3 3 11 2 1 1 14 11 0 1 1 0.18 0.10 48 P -1 0 0 0 -3 0 1 -3 0 -2 0 2 -1 -3 5 -1 0 -3 -3 -2 3 4 4 5 0 2 10 1 2 1 10 15 2 1 30 3 6 0 0 1 0.47 0.18 49 N 0 0 3 -1 1 0 1 -2 0 -1 -1 0 -1 -2 -2 1 2 -2 -1 0 5 4 22 1 4 3 9 2 2 3 6 6 0 1 1 7 15 0 3 7 0.16 0.10 50 I 0 0 -2 -2 1 -1 0 -1 -2 1 1 0 2 -1 1 -1 1 -2 -1 1 6 5 1 1 4 1 7 4 1 10 13 4 7 1 8 3 11 0 2 11 0.07 0.06 51 E -1 1 0 2 -1 2 3 -2 -1 -2 -1 1 -2 -1 0 0 0 -2 -2 -1 2 7 5 10 1 9 23 2 0 1 6 7 0 4 3 7 6 0 1 4 0.19 0.10 52 L -1 -1 -1 -2 -2 -2 -2 -2 -2 2 3 0 1 0 -1 -1 0 -2 -1 1 3 3 2 1 0 1 2 4 1 16 33 8 2 3 3 4 8 0 1 5 0.16 0.10 53 Q -1 1 1 0 -2 3 1 -2 1 -2 -1 1 0 -1 -1 1 1 0 -2 -2 2 6 7 5 0 17 6 2 4 2 7 8 2 2 3 11 12 2 1 1 0.16 0.11 54 K -1 1 1 0 -2 1 0 0 -1 -1 -2 3 -2 -3 -2 1 1 -3 -2 -1 4 6 6 5 0 5 5 9 0 4 3 24 0 1 1 13 8 0 1 3 0.18 0.11 55 D 0 0 1 4 -3 0 2 1 -1 -1 -2 -1 -2 -3 -2 1 0 -3 -3 -1 5 7 6 24 0 3 14 11 1 3 2 1 0 1 1 10 5 0 0 4 0.28 0.15 56 S 1 0 0 -2 -1 1 -1 0 3 0 -2 0 -2 -2 0 3 1 -3 -2 -2 9 6 4 1 1 6 2 7 9 7 2 4 0 1 4 27 7 0 0 2 0.21 0.16 57 D 0 0 1 3 -3 0 1 -1 2 -2 -1 1 -2 -1 -1 0 0 -3 1 -2 6 3 5 18 0 2 9 4 7 1 7 12 0 3 3 5 8 0 6 2 0.16 0.11 58 C -1 -2 -4 -3 9 -2 -4 -3 -1 1 -2 -2 -3 -3 -2 -1 0 -1 0 0 4 2 0 1 48 1 1 2 2 8 3 2 0 0 3 5 6 1 4 6 1.19 0.40 59 C 1 1 1 0 4 0 0 1 0 -2 0 0 -2 -3 0 1 -1 -3 -2 -2 10 7 8 4 11 3 5 10 2 1 12 4 0 0 4 14 2 0 1 1 0.12 0.10 60 S 1 -2 1 0 1 0 0 0 1 -2 -2 -1 -3 -2 4 1 0 -4 -1 -1 10 1 6 5 3 3 6 6 3 1 4 2 0 1 26 10 6 0 2 4 0.35 0.17 61 C -5 -8 -7 -8 11 -3 -8 -3 -7 -6 -6 -7 -6 -7 -7 -3 -3 -7 -7 -2 0 0 0 0 90 1 0 3 0 0 0 0 0 0 0 2 1 0 0 3 3.65 0.95 62 Q -2 -4 -1 -1 -5 -2 -1 -5 -2 -5 -1 -1 -5 -6 7 1 -3 -6 -5 -3 3 0 3 4 0 2 4 0 1 0 6 4 0 0 61 10 1 0 0 2 1.49 0.52 63 E -2 1 0 -1 -4 2 2 -3 1 -2 -2 2 -3 -2 3 1 0 2 -1 -1 1 7 3 2 0 9 17 1 3 2 4 11 0 1 14 11 4 3 2 4 0.27 0.18 64 K -3 -2 3 4 -5 -2 0 4 3 -5 -4 -1 -2 -5 -2 -1 -2 -5 0 -5 0 2 15 27 0 1 5 28 6 0 1 4 1 0 1 3 2 0 3 0 0.69 0.32 65 W -7 -8 -8 -9 -7 -7 -8 -7 -7 -8 -7 -8 -6 -4 -9 -3 -3 13 -3 -8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 2 95 0 0 4.77 1.16 66 V -2 -1 0 -2 -3 0 0 -3 1 3 1 1 0 1 -3 1 0 -3 -1 1 1 2 4 2 0 4 5 0 5 21 13 9 2 6 0 11 7 0 1 8 0.14 0.14 67 G 0 -2 0 -3 2 0 -1 1 -1 -3 -2 0 -2 1 2 2 0 6 1 -2 8 1 5 0 5 3 4 10 1 1 4 5 1 6 10 16 4 11 4 1 0.27 0.18 68 Y -5 -5 0 -6 -6 -3 -5 -6 6 -4 -3 -4 -4 5 -6 -3 -5 -2 7 -2 0 0 5 0 0 1 0 0 20 0 2 1 0 25 0 2 0 0 40 3 1.62 0.55 69 R -3 2 2 0 -2 3 2 2 -1 -5 -4 1 -4 -5 -4 -1 -1 0 -4 -4 0 13 11 5 1 18 13 19 1 0 1 9 0 0 0 4 3 2 0 0 0.50 0.27 70 C -2 0 3 2 0 0 1 3 -3 -3 -4 0 -2 -5 -4 1 -1 -5 -4 -3 1 5 17 14 3 4 8 28 0 1 1 6 1 0 0 9 3 0 0 2 0.47 0.24 71 N -2 -1 4 0 -5 -1 -2 -4 5 -5 -5 4 -4 -1 -4 2 -1 -5 0 -5 1 2 21 4 0 2 0 0 14 0 0 29 0 2 0 20 2 0 4 0 0.76 0.37 72 C -5 -8 -7 -8 12 -7 -8 -7 -7 -6 -6 -8 -6 1 -7 -5 -5 -6 -6 -5 0 0 0 0 94 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 3.97 0.98 73 Y -6 -6 -6 -7 -6 -6 -6 -7 -3 -2 -1 -6 -5 4 -7 -6 -6 -2 9 -5 0 0 0 0 0 0 0 0 0 2 5 0 0 15 0 0 0 0 78 0 2.65 0.84 74 F -4 0 -4 -5 -2 0 -4 -3 2 -2 0 2 1 4 -5 -2 -4 4 6 -3 0 5 0 0 1 4 0 2 6 1 11 13 4 19 0 2 0 5 26 0 0.71 0.35 75 I -2 -5 -5 -6 -4 -3 -5 -6 1 2 0 -5 0 7 -2 -4 -2 -3 1 3 4 0 0 0 0 1 0 0 3 9 9 0 2 45 2 0 2 0 3 20 0.98 0.41 76 S -2 -3 -1 -4 -4 -2 -3 -1 1 -1 -2 -4 -4 5 -4 5 -1 -4 -1 -2 2 1 3 0 0 2 1 3 3 4 3 0 0 24 0 50 2 0 2 2 0.84 0.45 77 S -1 0 2 0 -4 2 2 -1 0 -2 -2 2 1 -2 0 0 1 -4 -2 -2 3 5 13 3 0 9 14 4 2 2 2 12 4 1 4 8 9 0 1 2 0.22 0.16 78 E -2 -1 0 2 -5 1 4 -1 0 -1 -3 -1 -3 -3 0 1 0 -5 0 -2 1 3 3 13 0 5 36 4 2 4 1 3 0 1 5 9 6 0 3 3 0.45 0.27 79 Q 0 2 0 -2 -3 1 1 -1 -1 -3 -1 2 -1 -2 1 1 0 2 0 -2 6 14 4 1 0 6 10 3 1 0 5 14 2 1 6 14 4 3 3 2 0.20 0.15 80 K -2 3 2 0 -5 1 1 -1 -2 -2 -2 4 1 0 -3 0 -1 -4 -3 -2 1 16 10 5 0 4 7 3 0 2 3 30 5 5 0 5 3 0 0 2 0.40 0.25 81 T -2 -2 4 -1 -4 -1 -3 -4 -4 -1 -4 -3 -1 -2 1 2 5 -6 -4 -3 2 1 22 3 0 2 0 0 0 4 0 0 2 2 8 16 38 0 0 1 0.77 0.42 82 W -7 -7 -8 -9 -7 -7 -8 -7 -7 -7 -6 -3 -6 1 -9 -8 -7 13 1 -8 0 0 0 0 0 0 0 0 0 0 0 2 0 4 0 0 0 90 4 0 4.50 1.17 83 N 1 -1 2 1 -4 1 3 -3 2 -3 -3 0 -2 -3 -2 1 1 -4 1 -1 15 1 12 8 0 6 21 0 5 1 1 4 1 0 1 9 7 0 5 4 0.29 0.21 84 E -1 -1 0 4 -5 0 4 0 0 -3 -2 1 -4 0 -4 -1 -1 -5 -4 -4 4 3 3 26 0 4 29 8 2 2 4 7 0 4 0 3 2 0 0 0 0.51 0.28 85 S 5 -4 -1 -4 3 -4 -4 1 -4 -5 -5 -4 -4 -6 -4 4 -3 -6 -5 -4 46 0 2 0 6 0 0 9 0 0 0 0 0 0 0 37 0 0 0 0 1.11 0.52 86 R -3 3 -3 -1 -5 4 4 -4 0 -3 0 3 -1 -5 -4 -3 -3 -5 -2 -1 1 14 0 3 0 20 25 0 2 1 10 19 1 0 0 0 1 0 1 4 0.63 0.35 87 H 0 2 0 0 -4 2 0 -3 -1 -2 0 2 2 -2 -3 0 0 -2 0 -1 10 14 4 4 0 12 5 0 1 1 8 18 6 1 0 5 6 0 3 3 0.21 0.17 88 L 1 -1 1 0 -4 -1 -1 -4 -1 -2 -2 0 -3 5 -4 0 -1 -3 3 -3 16 3 8 7 0 3 3 0 1 1 3 5 0 33 0 6 3 0 9 0 0.51 0.31 89 C -5 -8 -8 -8 12 -8 -9 -7 -8 -6 -6 -8 -6 -7 -8 -6 -6 -7 -7 -6 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4.39 1.15 90 A 0 1 -1 -1 -3 3 0 -2 -1 -1 0 1 2 -3 -3 1 1 -2 -3 -1 7 8 1 3 0 17 4 2 1 3 10 10 6 1 0 11 12 0 0 3 0.19 0.18 91 S 1 0 -1 2 -3 2 2 0 1 -3 -1 1 -1 -4 -3 2 0 -4 -3 -2 14 3 2 11 0 8 16 6 4 1 5 6 2 0 0 15 4 0 0 1 0.25 0.19 92 Q -3 0 -1 -1 -5 4 2 -3 2 -3 0 2 3 0 -2 -2 -3 -4 1 -1 1 3 2 2 0 26 12 1 5 0 10 15 9 3 1 2 0 0 5 3 0.43 0.29 93 K -1 -2 4 1 -5 2 0 4 3 -5 -5 0 -3 -5 -4 1 -2 -5 -3 -4 3 2 22 7 0 8 6 29 8 0 0 5 0 0 0 8 1 0 1 1 0.62 0.32 94 S 4 -4 -1 -2 -4 -3 -1 1 -4 -4 -3 -2 -4 -5 -1 4 -1 -5 -5 -2 38 0 2 1 0 0 4 10 0 0 3 1 0 0 2 36 1 0 0 2 0.76 0.42 95 S -2 -2 2 0 -5 2 -1 0 7 -4 -5 -2 -4 -4 -1 1 2 -5 -2 -2 1 1 8 6 0 9 3 8 28 1 0 0 0 0 3 12 16 0 1 3 0.66 0.36 96 L -5 -6 -7 -7 -5 -5 -6 -3 -6 -1 6 -6 1 -3 -6 -6 -5 -5 -5 -3 0 0 0 0 0 0 0 2 0 2 93 0 2 0 0 0 0 0 0 0 1.83 0.66 97 L 2 -4 -5 -5 -3 -2 -4 -3 -5 2 3 -4 -1 -2 -2 -2 0 -4 -3 4 17 0 0 0 0 2 0 1 0 8 30 0 1 1 2 2 4 0 0 31 0.55 0.31 98 Q -2 0 -2 -1 -2 2 -2 -4 -2 1 0 2 -2 -1 -4 3 -1 -5 -3 1 1 5 1 2 0 10 0 0 0 8 11 17 0 2 0 30 3 0 0 9 0.33 0.28 99 L -3 -6 -6 -6 -4 -6 -4 -6 -6 7 1 -6 0 3 -4 -5 -3 -5 -3 2 2 0 0 0 0 0 1 0 0 61 8 0 2 14 1 0 1 0 0 11 1.31 0.51 100 Q -2 0 3 3 -3 2 2 -2 4 -3 -2 0 -3 -4 -2 0 0 -5 -1 -3 3 3 14 18 0 12 11 2 14 1 3 4 0 0 1 7 4 0 1 2 0.44 0.25 101 N -3 -4 4 3 -4 -3 -3 -2 0 -2 -5 -2 -4 -5 -4 5 3 -6 -5 -4 0 0 18 14 0 0 0 3 2 2 0 1 0 0 0 42 18 0 0 0 0.93 0.48 102 T 0 1 0 -1 -3 2 2 -2 0 -1 -1 1 -1 -2 1 1 1 -1 -2 -2 6 8 4 2 0 12 15 2 1 3 7 10 1 1 7 9 9 1 1 2 0.18 0.14 103 D 1 -3 2 3 -6 1 5 -2 -3 -5 -4 1 -4 -6 -4 -2 -2 -6 -5 -5 10 0 9 15 0 5 47 2 0 0 2 7 0 0 0 1 1 0 0 0 0.90 0.43 104 E -4 -4 -4 2 -7 -2 7 -4 -4 -4 -6 -1 -5 -6 -5 -3 -2 -6 -6 -2 1 0 0 9 0 0 78 1 0 1 0 3 0 0 0 1 2 0 0 4 1.72 0.67 105 L 0 -3 -2 -4 -4 4 -2 -2 0 -1 3 -2 3 -1 -3 -2 -2 -4 -3 2 8 0 2 0 0 22 0 3 3 1 32 1 8 3 1 1 1 0 0 14 0.46 0.31 106 D -1 0 3 4 -5 0 3 -2 -3 -3 -4 2 -2 -5 -3 0 -1 -5 -4 -4 6 6 15 25 0 3 19 3 0 2 1 11 1 0 0 6 3 0 0 0 0.54 0.29 107 F -5 -6 -3 -2 -6 -6 -4 -4 -5 -4 -1 -4 -2 8 -7 -3 -5 2 1 -2 0 0 1 2 0 0 1 1 0 0 4 1 1 77 0 2 0 2 3 3 1.99 0.67 108 M -2 -3 -5 -5 -4 -2 -5 -6 -5 4 4 -4 2 0 -5 -2 -3 -4 -3 3 2 1 0 0 0 2 0 0 0 24 37 0 5 3 0 3 0 0 0 22 0.76 0.34 109 S 0 1 0 -1 -3 2 -1 -1 -1 -1 -1 2 0 -3 -3 2 1 -4 0 1 6 7 5 2 0 10 1 3 1 2 4 16 2 0 0 19 7 0 3 11 0.19 0.18 110 S -1 1 0 0 -3 1 0 -1 1 -2 -1 2 -1 0 -1 2 0 -3 0 -2 4 9 4 4 0 6 3 5 3 1 8 17 1 6 2 17 6 0 3 2 0.15 0.14 111 S -1 0 1 -1 -3 0 0 1 1 -1 -3 1 -2 -1 -1 2 0 -3 0 -1 3 6 7 3 0 3 5 14 4 5 1 11 1 3 2 20 5 0 4 4 0.15 0.14 112 Q 0 1 0 0 -3 1 1 -1 1 -1 -1 2 -1 -3 0 1 1 1 -2 -1 6 8 4 6 0 6 8 5 3 3 4 14 1 0 4 10 10 3 1 4 0.12 0.10 113 Q -1 2 0 2 -4 2 1 1 0 -2 -3 1 -1 0 -1 1 -1 -4 -1 -3 2 12 5 12 0 9 10 10 2 2 1 9 1 4 3 14 3 0 2 1 0.21 0.16 114 F -1 -1 1 0 -4 -2 0 0 1 0 -1 -2 -1 4 0 1 -2 -2 3 -1 3 2 7 5 0 1 6 6 3 5 6 1 2 21 5 13 0 0 10 4 0.20 0.18 115 Y -2 -3 -4 -5 -1 -1 -4 -2 3 -1 -2 -4 -2 5 -3 0 -1 -2 5 2 2 1 0 0 2 3 0 3 7 3 3 0 1 26 1 7 4 0 24 14 0.73 0.36 116 W -7 -8 -8 -9 -7 -7 -8 -7 -2 -7 -6 -8 -6 2 -8 -8 -7 13 -3 -8 0 0 0 0 0 0 0 0 1 0 0 0 0 7 0 0 0 91 0 0 4.64 1.23 117 I -5 -6 -6 -7 -5 -6 -6 -7 -6 7 1 -6 5 -2 -6 -5 0 -6 -5 1 0 0 0 0 0 0 0 0 0 64 8 0 13 1 0 0 5 0 0 8 1.57 0.58 118 G -3 -6 -2 -3 -6 -6 -6 7 -6 -7 -5 -5 -6 -7 -6 -4 -5 0 -7 -7 1 0 1 1 0 0 0 93 0 0 2 0 0 0 0 0 0 1 0 0 2.38 0.78 119 L -2 -5 -7 -7 -5 -5 -4 -7 -1 0 6 -6 0 -3 -6 -6 -4 -2 -4 0 4 0 0 0 0 0 1 0 1 3 82 0 2 0 0 0 0 0 0 5 1.50 0.59 120 S -2 2 2 -3 -4 -1 -2 -2 3 -3 -3 0 -3 0 -4 4 1 0 -1 -2 1 14 12 0 0 2 1 1 8 1 3 6 0 4 0 33 7 2 2 2 0.45 0.30 121 Y -3 3 1 4 -3 0 -2 -4 0 -3 -1 0 0 0 -2 -2 -3 0 4 -3 1 18 7 27 0 4 0 0 2 1 6 4 2 3 2 2 0 1 16 1 0.55 0.32 122 S -1 1 1 1 -3 0 0 -2 -1 0 -1 0 -1 -1 1 1 1 -4 -2 1 1 7 7 11 0 4 7 3 1 7 7 6 1 2 7 9 9 0 1 10 0.09 0.09 123 E -2 0 2 1 -4 1 1 0 -1 -4 -2 2 -2 -3 0 1 -1 6 -3 -4 2 3 11 8 0 6 10 8 1 0 4 15 1 1 6 10 4 11 0 0 0.36 0.24 124 E 0 1 2 0 -3 2 0 -1 -1 -1 -2 2 -1 -1 1 1 1 -4 -3 -1 5 7 11 3 0 10 6 3 1 5 3 13 1 3 5 15 7 0 0 3 0.17 0.15 125 H -2 0 3 2 -5 2 4 0 2 -2 -4 2 -4 -5 -1 -1 -3 -5 -4 -3 2 5 13 10 0 7 28 7 4 3 0 12 0 0 3 4 0 0 0 1 0.49 0.28 126 T -1 1 0 -1 4 0 -1 3 3 -4 -4 2 1 -3 -2 0 -1 -4 -2 -2 2 7 5 4 12 4 2 21 9 0 0 13 4 1 1 7 4 0 1 3 0.34 0.22 127 A 0 0 1 1 -3 0 0 0 1 -1 -2 -1 -1 -3 2 2 1 -4 -2 -2 5 5 8 9 0 5 6 6 4 4 3 2 2 1 12 17 9 0 1 2 0.19 0.15 128 W -7 -4 -8 -8 -7 -6 -7 -7 -6 -6 -2 -5 -6 3 -5 -3 -5 12 1 -6 0 1 0 0 0 0 0 0 0 0 3 1 0 11 1 3 1 74 3 1 3.56 1.04 129 L -1 3 -3 -3 -4 3 1 -2 2 -2 1 3 -1 -1 -2 -2 -2 -4 -2 0 3 14 0 0 0 15 11 3 4 1 17 18 1 2 1 1 1 0 1 6 0.32 0.24 130 W -7 -4 -8 -8 -7 -7 -7 -7 -7 -7 -3 -7 -6 -4 -8 -7 -2 13 -3 -7 0 1 0 0 0 0 0 0 0 0 3 0 0 0 0 0 3 91 0 0 4.58 1.26 131 E -1 -2 -2 -1 -3 -2 2 -3 -2 2 -1 -2 1 -2 -2 3 2 -5 -3 2 2 1 1 3 0 1 16 1 1 15 4 1 3 1 1 23 13 0 0 14 0.34 0.27 132 N -4 -5 5 7 -7 -4 -2 -4 -4 -7 -7 -4 -6 -7 -5 -3 -2 -8 -6 -7 1 0 28 65 0 0 2 1 0 0 0 0 0 0 0 1 2 0 0 0 2.01 0.73 133 G -3 -3 1 0 -6 -2 -2 7 -1 -7 -7 -2 -6 -6 -6 -2 -5 -6 -2 -7 1 1 5 5 0 1 2 77 1 0 0 3 0 0 0 2 0 0 2 0 1.69 0.63 134 S 1 -3 -2 -2 -4 -1 -1 -4 0 -1 -2 -3 -1 -5 -1 5 4 -6 -4 -1 8 1 0 1 0 2 3 0 3 4 3 1 2 0 3 41 25 0 0 3 0.70 0.43 135 A 1 -2 1 -1 -4 -1 0 -2 -2 -1 -2 1 -1 -1 4 2 1 -5 -3 0 11 1 6 2 0 2 4 2 1 3 2 11 1 3 21 16 8 0 0 6 0.33 0.22 136 L -2 -3 -3 -5 -4 -4 -5 -5 -4 1 4 -3 0 4 0 -4 -1 -1 2 2 2 1 2 0 0 0 0 0 0 5 40 2 1 17 5 0 3 1 7 15 0.63 0.31 137 S -2 -1 3 2 -3 0 0 -2 1 -2 -1 0 -1 -3 0 3 2 -4 -3 -2 1 2 17 10 0 3 4 2 3 1 6 6 1 0 5 22 13 0 0 2 0.30 0.21 138 Q -2 -1 1 -1 -3 2 0 -1 2 -3 -1 1 -2 1 2 1 0 -2 3 -3 1 2 6 2 0 10 4 4 5 1 6 8 0 7 11 15 4 0 13 1 0.25 0.19 139 Y -2 0 2 1 -3 0 1 -1 1 -2 -2 1 -1 1 -2 0 1 2 2 -2 1 3 11 7 0 4 11 4 3 2 3 10 2 6 1 7 13 3 9 2 0.17 0.14 140 L 0 -1 1 -2 -2 -1 -2 -1 0 1 2 -1 0 1 -1 -1 -1 2 0 1 9 4 9 2 0 2 2 4 2 8 26 5 2 5 2 5 1 3 4 8 0.08 0.09 141 F -1 -1 -2 -3 -4 -3 -1 -4 -1 0 1 -2 0 5 -4 -3 -2 8 1 -2 5 3 2 1 0 1 4 1 1 4 16 3 2 22 1 2 3 25 4 1 0.89 0.35 142 P -1 -1 2 0 -3 -1 0 -1 0 -2 -2 1 -3 -2 4 1 0 2 -2 -2 3 3 9 5 0 2 7 5 2 1 3 10 0 2 22 11 5 4 1 3 0.33 0.18 143 S 1 0 1 2 -3 1 1 0 0 -1 -2 0 -2 -2 0 2 0 -3 -2 -2 12 5 7 11 0 8 7 6 2 5 2 4 1 2 4 17 4 0 1 2 0.16 0.13 144 F -2 -1 -1 0 -3 -2 0 1 1 1 -1 -1 0 3 -1 0 0 2 2 -1 1 3 3 5 0 0 6 13 4 8 6 2 3 13 3 10 4 3 8 4 0.10 0.12 145 E -2 0 0 1 -4 1 4 0 0 -3 -3 1 -3 -1 0 0 1 0 -2 -3 2 4 5 6 0 7 28 8 2 1 2 7 0 3 5 5 11 1 1 1 0.32 0.22 146 T 0 -1 1 1 -1 0 0 0 0 -1 -1 -1 0 -1 3 1 0 -2 -1 -1 8 2 8 7 1 5 4 6 2 5 5 3 2 3 16 11 6 0 2 3 0.14 0.10 147 F -1 -1 2 0 -3 -1 -1 0 0 0 0 -1 -1 2 -1 0 0 4 2 -1 5 2 10 6 0 3 3 8 2 5 8 4 1 9 2 5 5 7 10 3 0.12 0.10 148 N -1 1 4 1 -3 -1 1 2 -1 -3 -4 1 -3 -3 1 0 0 -1 -2 -2 4 6 22 9 0 2 8 17 1 1 1 7 0 1 6 6 4 1 2 2 0.32 0.19 149 T 0 -1 1 0 0 -1 2 1 -2 -1 -2 1 0 -1 1 1 0 -1 -3 -2 5 2 7 4 2 1 16 11 0 4 3 10 2 3 6 14 7 1 0 2 0.15 0.14 150 K -2 1 0 0 -2 1 4 1 0 -4 -4 2 -2 -3 1 0 -2 -4 -4 -3 2 9 5 5 1 4 26 13 2 1 1 13 1 1 6 6 1 0 0 1 0.38 0.24 151 N -3 -1 5 4 -3 -1 0 -1 1 -3 -3 -1 -1 0 -2 1 -1 -5 -1 -3 0 3 29 21 1 3 6 3 3 2 2 4 1 4 1 9 3 0 3 2 0.53 0.31 152 C -5 -5 -2 -5 11 -7 -7 -3 1 -2 -6 -7 -6 -7 -3 -1 -3 -7 -7 -2 0 1 2 1 78 0 0 2 4 2 0 0 0 0 1 4 1 0 0 3 3.04 0.98 153 I 2 -4 -4 -3 4 -3 -4 0 -4 2 -1 -3 -1 1 -4 -1 -2 -4 -3 4 22 0 0 1 9 1 1 7 0 11 3 0 1 5 0 5 1 0 0 31 0.49 0.29 154 A 3 -3 -2 -3 2 -2 1 1 0 0 -2 -3 1 -1 -3 0 0 0 0 1 26 0 1 0 5 0 10 11 3 4 3 0 4 2 0 7 5 1 4 14 0.23 0.22 155 Y -3 -4 -3 -5 -1 -4 -3 -3 1 2 2 -3 2 3 -5 -1 -4 5 5 -1 2 0 1 0 1 0 2 1 4 12 18 1 6 13 0 5 0 8 21 4 0.64 0.34 156 N -2 0 3 -1 -3 1 0 -1 2 1 0 1 -2 -1 -3 1 1 -1 0 -2 1 5 14 2 0 5 5 5 6 9 9 11 0 3 0 9 9 1 3 1 0.14 0.16 157 P 0 -1 -1 0 -2 0 0 0 1 -2 -1 1 -2 -2 2 2 1 -3 -1 -1 6 1 1 4 1 4 7 6 4 2 8 8 0 1 10 22 8 0 2 4 0.17 0.16 158 N -1 2 2 2 -4 0 1 -1 1 -4 -3 0 -3 -3 -3 2 2 -1 -3 -3 5 11 12 13 0 4 7 5 4 0 3 6 0 1 0 15 13 1 1 1 0.32 0.24 159 G -1 -2 0 1 -3 -3 -2 5 -1 -5 -5 1 -3 -2 -2 0 0 -1 -3 -3 4 2 4 8 1 0 3 48 1 0 0 8 1 2 2 6 7 1 1 2 0.70 0.37 160 N -1 2 4 -1 -2 2 0 -1 2 -2 -2 2 -2 -4 -3 -1 1 2 -3 -2 3 9 25 2 1 9 6 3 4 2 5 12 1 0 1 3 8 3 0 2 0.37 0.27 161 A -1 -3 -1 -5 -2 1 -4 -1 0 2 0 -2 -2 1 -4 -4 -3 9 2 2 5 1 3 0 1 7 0 5 2 13 7 3 1 6 1 1 1 26 6 14 0.83 0.41 162 L -3 -3 3 -1 -4 -2 -2 -3 2 -1 2 0 2 2 -3 -1 -2 4 3 0 1 0 15 3 0 1 2 1 4 3 18 7 5 9 1 4 1 7 9 6 0.31 0.23 163 D 1 -1 -1 5 -5 -3 -1 -3 -2 -3 -5 -2 -5 -3 0 3 -1 -6 -2 -2 11 3 2 39 0 0 3 1 1 2 0 2 0 1 4 24 2 0 2 4 0.78 0.45 164 E 1 2 0 2 -4 1 3 -3 -2 -2 -3 1 0 -2 -3 0 1 0 -2 0 11 10 4 12 0 7 18 0 1 1 2 8 3 2 0 5 8 1 1 7 0.25 0.21 165 S -1 0 2 3 -4 0 -1 -1 -1 -2 -3 0 -3 1 2 2 -1 -4 0 -2 3 5 12 16 0 3 3 3 1 2 1 5 0 6 11 19 3 0 4 2 0.30 0.23 166 C -6 -9 -8 -4 12 -9 -9 -8 -9 -7 -7 -9 -7 -8 -8 -6 -6 -8 -3 -6 0 0 0 1 98 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 4.48 1.34 167 E -1 0 3 2 -1 0 3 -2 -3 -2 -3 0 -4 -3 -4 3 0 -5 -2 -4 3 6 12 10 1 3 19 3 0 3 3 4 0 1 0 25 6 0 1 0 0.41 0.30 168 D 0 1 1 1 -3 0 1 -2 -2 -2 -1 1 0 -2 -3 2 1 -2 0 -1 5 7 5 10 0 3 10 2 0 1 6 8 2 1 0 19 10 0 4 5 0.18 0.18 169 K -2 2 0 1 -4 -1 0 -4 2 -2 -1 3 0 -3 2 -1 2 0 -2 -1 3 9 3 7 0 0 6 0 5 1 7 21 2 0 11 4 13 1 1 5 0.28 0.23 170 N -1 1 4 -1 -2 0 -2 -3 4 -1 0 2 -3 1 -4 -1 -2 -4 2 -4 4 9 21 2 1 4 2 1 10 3 10 13 0 6 0 4 1 0 9 0 0.37 0.27 171 R -2 4 2 -3 -5 -1 -3 -1 3 -2 -3 1 -2 1 1 0 0 -3 4 -4 3 21 10 0 0 2 0 4 7 3 2 7 1 6 8 5 5 0 15 0 0.41 0.29 172 Y -6 -4 -6 -7 1 -6 -7 -5 -5 -3 -3 -6 -5 6 -7 0 -3 9 6 -2 0 1 0 0 3 0 0 1 0 2 2 0 0 28 0 7 2 29 23 3 1.88 0.72 173 I -2 -6 -6 -7 -5 -6 -6 -7 -2 7 0 -6 -1 -4 -6 -5 0 -6 -3 4 3 0 0 0 0 0 0 0 1 55 6 0 1 0 0 0 5 0 1 28 1.45 0.60 174 C -6 -9 -8 -9 12 -9 -9 -8 -9 -7 -4 -9 -7 -8 -8 -6 -6 -8 -8 -6 0 0 0 0 99 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 4.54 1.33 175 K -2 -1 -3 -3 -7 4 4 -3 -4 -6 -6 5 0 -7 -5 -2 -4 -6 -5 -3 2 2 1 0 0 16 30 1 0 0 0 41 2 0 0 3 0 0 0 2 1.22 0.60 176 Q -2 2 -4 -4 -6 1 -1 -5 0 -3 -4 6 3 2 -5 -2 -1 -5 -3 -5 2 12 0 0 0 4 2 0 3 1 1 52 8 9 0 2 4 0 1 0 1.01 0.50 177 Q -3 3 -2 -1 -5 3 3 -2 -2 -3 -4 3 -2 -5 1 -1 -1 -5 -1 -3 0 16 1 3 0 15 19 3 0 2 0 23 1 0 7 3 4 0 2 2 0.55 0.31 178 L 0 -3 -4 -2 -3 -3 -4 -5 -4 1 4 0 1 -1 -4 -3 -1 -4 0 1 6 0 0 2 0 0 0 0 0 4 58 8 3 2 0 0 3 0 3 10 0.60 0.28 179 I -2 -4 -4 -4 -2 -4 -4 -5 -4 5 1 -4 3 -1 -4 -3 -2 -4 -2 3 0 0 0 0 0 0 0 0 0 59 6 0 9 0 0 0 0 0 0 26 0.80 0.21 K Lambda Standard Ungapped 0.1318 0.3192 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1318 0.3192 PSI Gapped 0.0410 0.2670