Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 M -1 -2 -3 -4 -2 -1 -2 -3 -2 1 2 -2 7 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.42 0.02 2 Y -2 -2 -3 -4 -2 -2 -3 -4 0 1 3 -3 1 2 -3 -2 -2 1 5 0 0 0 0 0 0 0 0 0 0 0 57 0 0 0 0 0 0 0 43 0 0.41 0.01 3 S 0 -2 -1 -1 -2 -1 -1 -1 -2 -3 -3 -1 -2 -3 7 3 0 -4 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 57 43 0 0 0 0 1.06 0.01 4 F -3 -3 -3 -4 -3 -4 -4 -4 -1 0 0 -4 0 7 -4 -3 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.79 0.02 5 V 0 -3 -3 -4 -1 -3 -3 -4 -4 3 1 -3 1 -1 -3 -2 0 -3 -1 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.38 0.01 6 S 0 0 0 -1 -2 4 1 -1 4 -3 -3 0 -1 -3 -1 3 0 -3 -1 -2 0 0 0 0 0 40 0 0 17 0 0 0 0 0 0 43 0 0 0 0 0.37 0.01 7 E -1 0 0 2 -4 2 6 -2 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.77 0.01 8 E -1 2 0 3 -4 4 3 -2 0 -4 -3 1 -2 -4 -2 0 -1 -3 -2 -3 0 16 0 25 0 29 31 0 0 0 0 0 0 0 0 0 0 0 0 0 0.51 0.02 9 T -1 -2 -1 -2 -1 -2 -2 -3 -3 3 0 -2 0 -1 -2 0 4 -3 -2 1 0 0 0 0 0 0 0 0 0 44 0 0 0 0 0 0 56 0 0 0 0.29 0.02 10 G 2 -2 -1 -2 -2 -2 -2 6 -2 -3 -3 -2 -3 -3 -2 0 -1 -3 -3 -2 25 0 0 0 0 0 0 75 0 0 0 0 0 0 0 0 0 0 0 0 0.77 0.02 11 T 1 -2 -2 -2 -1 -1 -2 -2 -2 -1 0 -2 0 -1 -2 0 3 8 0 -1 16 0 0 0 0 0 0 0 0 0 16 0 0 0 0 0 44 25 0 0 0.46 0.02 12 L -2 -3 -3 -4 -2 -3 -3 -4 -1 1 2 -3 1 4 -4 -3 -2 0 4 0 0 0 0 0 0 0 0 0 0 13 31 0 0 32 0 0 0 0 25 0 0.40 0.01 13 I -1 -3 -4 -4 -1 -3 -4 -4 -4 5 1 -3 1 0 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 0 0 25 0.41 0.02 14 V 0 -3 -2 -3 -1 -2 -3 2 -3 2 0 -2 0 -2 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 0 0 75 0.27 0.02 15 N -2 0 6 1 -3 3 0 -1 0 -4 -4 0 -2 -4 -2 0 0 -4 -2 -3 0 0 75 0 0 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.64 0.03 16 S -1 -2 -2 -2 -2 -2 -2 -2 -2 2 0 -2 0 5 -3 2 0 -1 1 0 0 0 0 0 0 0 0 0 0 25 0 0 0 44 0 31 0 0 0 0 0.23 0.02 17 V -2 -3 -3 -4 -2 -3 -3 -4 -2 1 0 -3 0 6 -4 -3 -2 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 69 0 0 0 0 0 31 0.51 0.02 18 L -2 -3 -4 -4 -2 -3 -4 -4 -3 3 3 -3 1 3 -3 -3 -1 -1 0 2 0 0 0 0 0 0 0 0 0 44 31 0 0 25 0 0 0 0 0 0 0.34 0.01 19 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 4 -3 2 3 -3 -3 -2 -1 0 1 0 0 0 0 0 0 0 0 0 0 84 0 0 16 0 0 0 0 0 0 0.44 0.02 20 F 0 -2 -1 -2 -1 -2 -2 -2 -2 0 0 -2 0 4 -2 1 2 -1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 31 0 16 28 0 0 25 0.19 0.01 21 L -1 -3 -4 -4 -1 -3 -3 -4 -3 2 3 -3 1 2 -3 -2 -1 -2 0 3 0 0 0 0 0 0 0 0 0 0 45 0 0 11 0 0 0 0 0 44 0.31 0.01 22 A 2 -2 -1 -2 -1 -1 -1 -1 -2 1 -1 -1 0 -2 -2 2 0 -3 -2 3 31 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0 44 0.19 0.01 23 F -1 -4 -3 -4 9 -4 -4 -3 -3 -1 -1 -4 -1 4 -4 -2 -2 -1 0 -1 0 0 0 0 69 0 0 0 0 0 0 0 0 31 0 0 0 0 0 0 0.90 0.03 24 V 3 -2 -3 -3 -1 -2 -2 -1 -3 2 0 -2 0 -2 -2 0 0 -3 -2 3 44 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 56 0.24 0.02 25 V -1 -3 -4 -4 -1 -3 -3 -4 -4 4 1 -3 1 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 53 0 0 0 0 0 0 0 0 0 47 0.39 0.02 26 F -1 -2 -2 -3 -2 -2 -2 -3 -2 -1 0 -2 0 5 -3 0 3 0 2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 56 0 0 44 0 0 0 0.40 0.02 27 L -2 -3 -4 -4 -2 -3 -3 -4 -3 2 5 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.51 0.02 28 L -1 -3 -4 -4 -1 -3 -3 -4 -3 3 4 -3 2 0 -3 -3 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 25 59 0 0 0 0 0 0 0 0 16 0.38 0.01 29 V -1 -3 -3 -4 -1 -3 -3 -4 -3 2 1 -3 0 3 -3 -2 -1 -2 0 4 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0 0 0 75 0.33 0.02 30 T 0 -3 -2 -3 7 -2 -3 -3 -3 0 -1 -2 -1 -2 -2 0 3 -3 -2 2 0 0 0 0 44 0 0 0 0 0 0 0 0 0 0 0 31 0 0 25 0.50 0.02 31 L -1 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 3 0 -3 -2 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 0 60 0 16 0 0 0 0 0 0 25 0.36 0.01 32 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.47 0.03 33 I -2 -3 -4 -4 -2 -3 -3 -4 -3 3 2 -3 1 2 -3 -3 -1 -2 0 2 0 0 0 0 0 0 0 0 0 47 25 0 0 16 0 0 0 0 0 13 0.32 0.01 34 L -2 -3 -4 -4 -2 -3 -3 -4 -3 2 5 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.51 0.02 35 T 2 -1 -1 -2 -1 -1 -1 -1 -2 -1 -2 -1 -1 -3 -1 1 5 -3 -2 0 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 75 0 0 0 0.41 0.02 36 A 4 -2 -1 -2 -1 -1 -1 0 -2 -1 -2 -1 -1 -3 -1 1 2 -3 -2 0 75 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0 0.36 0.02 37 L -1 -3 -3 -3 -1 -3 -3 -4 -3 4 3 -3 1 0 -3 -2 1 -3 -2 2 0 0 0 0 0 0 0 0 0 53 31 0 0 0 0 0 16 0 0 0 0.29 0.01 38 R -2 6 -1 -2 -4 1 0 -3 -1 -3 -3 3 -2 -3 -2 -1 -1 -3 -2 -3 0 75 0 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0.69 0.03 39 L -2 -3 -4 -4 -2 -3 -3 -4 -3 2 5 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.51 0.02 40 C -1 -4 -3 -4 10 -4 -4 -3 -4 -2 -2 -4 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.42 0.05 41 A 2 -3 -3 -3 -1 -2 -2 -2 -3 3 0 -2 0 -1 -2 -1 0 -3 -2 3 31 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 44 0.23 0.01 42 Y -1 0 -1 -1 -3 5 1 -3 1 -3 -2 1 -1 0 -2 -1 -1 0 4 -2 0 0 0 0 0 69 0 0 0 0 0 0 0 0 0 0 0 0 31 0 0.53 0.03 43 C -1 -4 -3 -4 9 -3 -4 -3 -4 2 -1 -4 -1 -2 -3 -2 -1 -3 -3 0 0 0 0 0 75 0 0 0 0 25 0 0 0 0 0 0 0 0 0 0 0.94 0.03 44 C 1 -3 -3 -4 8 -2 -3 -3 -3 0 0 -3 2 -2 -3 -1 -1 -3 -2 1 13 0 0 0 56 0 0 0 0 0 0 0 16 0 0 0 0 0 0 16 0.61 0.02 45 N 0 -1 4 0 -2 -1 -1 3 -1 -3 -3 -1 -2 -3 -2 2 2 -3 -2 -2 0 0 31 0 0 0 0 25 0 0 0 0 0 0 0 29 16 0 0 0 0.38 0.01 46 I -1 -3 -2 -3 -2 -3 -3 4 -2 2 0 -3 0 3 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 44 0 31 0 0 0 25 0 0 0 0 0 0 0.31 0.01 47 V -1 -3 -3 -4 7 -3 -4 -3 -3 1 0 -3 0 2 -3 -2 -1 -2 0 3 0 0 0 0 41 0 0 0 0 0 0 0 0 16 0 0 0 0 0 44 0.47 0.02 48 N -2 -1 6 1 -3 0 0 -1 4 -4 -4 0 -2 -3 -2 0 0 -4 -1 -3 0 0 84 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 0 0 0.71 0.03 49 V 0 -2 -2 -2 -1 -2 -2 -3 -3 3 0 -2 0 -1 -2 0 3 -3 -2 3 0 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 44 0 0 31 0.26 0.02 50 S -1 -2 -2 -2 -2 -2 -2 -2 -2 0 3 -2 1 3 -3 1 0 -1 0 0 0 0 0 0 0 0 0 0 0 0 44 0 0 25 0 31 0 0 0 0 0.19 0.01 51 L -1 -3 -4 -4 -1 -3 -3 -4 -3 3 4 -3 2 0 -3 -3 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 25 59 0 0 0 0 0 0 0 0 16 0.38 0.01 52 V -1 -3 -3 -4 -2 -3 -3 -4 -3 3 1 -3 1 4 -3 -2 -1 -1 1 3 0 0 0 0 0 0 0 0 0 25 0 0 0 29 0 0 0 0 0 47 0.32 0.02 53 K 0 1 -1 -1 -2 2 0 -2 -1 -1 0 2 0 -2 -2 1 0 -3 -2 0 0 0 0 0 0 16 0 0 0 0 16 31 0 0 0 25 0 0 0 13 0.15 0.01 54 P -1 -3 -2 -2 -3 -2 -1 -3 -3 -3 -3 -1 -3 -4 8 -1 -1 -4 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.12 0.04 55 T 3 -1 0 -1 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 3 2 -3 -2 -1 44 0 0 0 0 0 0 0 0 0 0 0 0 0 0 35 21 0 0 0 0.33 0.02 56 V 1 -3 -3 -3 -1 -2 -3 -2 -3 1 1 -2 1 3 -3 -1 -1 -2 0 2 25 0 0 0 0 0 0 0 0 0 16 0 0 23 0 0 0 0 0 37 0.18 0.01 57 Y -2 -2 -2 -3 -3 -1 -2 -3 4 -2 -2 -2 -1 3 -3 -2 -2 2 7 -2 0 0 0 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 84 0 0.86 0.04 58 V -1 -3 -4 -4 -1 -3 -3 -4 -4 3 2 -3 1 -1 -3 -2 -1 -3 -1 4 0 0 0 0 0 0 0 0 0 29 16 0 0 0 0 0 0 0 0 56 0.35 0.01 59 Y -2 -2 -3 -4 -3 -2 -3 -4 2 -2 -1 -2 -1 3 -4 -2 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.01 0.04 60 S 0 -1 5 1 -2 0 -1 2 0 -4 -4 -1 -2 -3 -2 2 0 -4 -2 -3 0 0 53 0 0 0 0 16 0 0 0 0 0 0 0 31 0 0 0 0 0.48 0.02 61 R -1 6 -1 -2 -3 1 0 -3 -1 -3 -2 2 -1 -3 -2 0 2 -3 -2 -2 0 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0 28 0 0 0 0.54 0.02 62 V 1 -3 -2 -2 -1 -2 -2 4 -3 1 -1 -2 -1 -2 -2 -1 -1 -3 -2 2 16 0 0 0 0 0 0 37 0 0 0 0 0 0 0 0 0 0 0 47 0.27 0.01 63 K 1 4 -1 -1 -3 1 0 -2 -1 -3 -3 4 -2 -3 -2 0 -1 -3 -2 -2 16 37 0 0 0 0 0 0 0 0 0 47 0 0 0 0 0 0 0 0 0.44 0.02 64 N -2 -1 4 0 -3 3 0 -2 1 -2 -2 0 -1 2 -3 0 -1 -1 3 -2 0 0 44 0 0 25 0 0 0 0 0 0 0 16 0 0 0 0 16 0 0.34 0.02 65 L -1 -2 -3 -3 -2 2 -1 -4 -2 1 3 -1 2 0 -3 -2 -1 -2 -1 2 0 0 0 0 0 20 0 0 0 0 60 0 0 0 0 0 0 0 0 20 0.25 0.01 66 N -2 0 4 3 -3 0 0 -2 0 -3 -3 2 -2 0 -2 0 -1 -1 4 -3 0 0 34 20 0 0 0 0 0 0 0 20 0 0 0 0 0 0 26 0 0.34 0.01 67 S 0 0 0 -1 -2 0 0 -1 -1 -2 -2 2 -1 2 -2 3 0 -2 0 -2 0 0 0 0 0 0 0 0 0 0 0 26 0 20 0 53 0 0 0 0 0.23 0.02 68 S 0 0 0 0 -2 3 1 -1 -1 -3 -3 2 -1 -3 -1 3 1 -3 -2 -2 0 0 0 0 0 20 0 0 0 0 0 20 0 0 0 60 0 0 0 0 0.36 0.02 69 E -1 2 -1 1 -4 1 4 -2 -1 -4 -3 1 -2 -4 4 0 -1 -3 -3 -3 0 17 0 0 0 0 58 0 0 0 0 0 0 0 26 0 0 0 0 0 0.65 0.01 70 G 0 -2 0 -1 -2 -1 -1 3 -2 -3 -3 -1 -2 -3 4 2 0 -2 -2 -2 1 1 1 1 0 1 1 32 0 1 1 1 0 1 26 28 1 0 1 1 0.50 0.00 71 V -1 -2 -2 -3 -2 -1 -2 -3 4 2 2 -2 1 -1 -3 -2 -1 -3 0 3 0 0 0 0 0 0 0 0 27 0 26 0 0 0 0 0 0 0 0 48 0.22 0.01 72 P -1 -2 -2 -2 -3 -2 -1 -3 -3 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.07 0.02 73 D -2 -2 0 5 -4 -1 1 -2 -2 -3 -4 -1 -3 -4 6 -1 -1 -5 -3 -3 0 0 0 61 0 0 0 0 0 0 0 0 0 0 39 0 0 0 0 0 0.96 0.00 74 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.00 75 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.00 76 V 0 -3 -3 -4 -1 -3 -3 -4 -4 3 1 -3 1 -1 -3 -2 0 -3 -1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.34 0.00 K Lambda Standard Ungapped 0.1407 0.3287 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1407 0.3287 PSI Gapped 0.0410 0.2670