Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 M -1 -1 -2 -3 -1 0 -2 -3 -2 1 2 -1 5 0 -3 -2 -1 -1 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.33 0.00 2 S 1 -1 1 0 -1 0 0 0 -1 -2 -2 0 -2 -2 -1 4 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.45 0.00 3 D -2 -2 1 6 -4 0 2 -1 -1 -3 -4 -1 -3 -4 -2 0 -1 -4 -3 -3 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.92 0.00 4 N -2 0 6 1 -3 0 0 0 1 -3 -3 0 -2 -3 -2 1 0 -4 -2 -3 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.72 0.00 5 G 0 -2 0 -1 -3 -2 -2 6 -2 -4 -4 -2 -3 -3 -2 0 -2 -3 -3 -3 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.04 0.00 6 P -1 -2 -2 -2 -3 -1 -1 -2 -2 -3 -3 -1 -3 -4 7 -1 -1 -4 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.03 0.00 7 Q -1 1 0 0 -3 5 2 -2 0 -3 -2 1 0 -3 -1 0 -1 -2 -1 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.64 0.00 8 S 0 0 0 0 -1 0 0 0 0 -1 -1 0 -1 -1 0 2 1 -1 -1 -1 5 3 3 4 1 3 4 5 1 3 6 4 2 3 4 37 4 1 2 4 0.10 0.00 9 N -2 0 6 1 -3 0 0 0 1 -3 -3 0 -2 -3 -2 1 0 -4 -2 -3 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.72 0.00 10 Q -1 1 0 0 -3 5 2 -2 0 -3 -2 1 0 -3 -1 0 -1 -2 -1 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.64 0.00 11 R -1 6 0 -2 -3 1 0 -2 0 -3 -2 2 -1 -3 -2 -1 -1 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.74 0.00 12 S 3 -1 2 0 -1 0 -1 0 -1 -2 -2 0 -1 -2 -1 2 1 -3 -2 -1 47 0 18 0 0 0 0 0 0 0 0 0 0 0 0 35 0 0 0 0 0.31 0.00 13 A 4 -1 -1 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -2 -1 2 0 -3 -2 -1 81 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0.41 0.03 14 P -1 -2 -2 -2 -3 -2 -1 -2 -2 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.13 0.04 15 R -1 4 -1 -2 -3 1 0 -2 -1 -1 -2 3 -1 -3 -2 -1 -1 -3 -2 0 0 39 0 0 0 0 0 0 0 0 0 43 0 0 0 0 0 0 0 19 0.39 0.03 16 I -1 -2 -2 -3 -1 -2 -2 -3 -3 3 1 -2 0 -1 -2 -1 2 -3 -2 3 0 0 0 0 0 0 0 0 0 43 0 0 0 0 0 0 28 0 0 29 0.30 0.03 17 T 0 0 0 -1 -1 0 -1 -2 -2 -1 -1 1 -1 -2 -1 2 4 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 18 0 0 0 16 58 0 0 8 0.34 0.04 18 F -2 -3 -4 -4 -2 -3 -3 -3 -2 0 1 -3 0 5 -4 -3 -2 7 2 -1 0 0 0 0 0 0 0 0 0 0 18 0 0 55 0 0 0 28 0 0 0.89 0.05 19 G 3 -1 -1 -2 -1 -1 -1 3 -2 -2 -2 1 -2 -3 -1 0 -1 -3 -2 -1 52 0 0 0 0 0 0 36 0 0 0 13 0 0 0 0 0 0 0 0 0.42 0.03 20 G -1 -1 2 4 -3 1 0 3 -1 -3 -4 -1 -3 -3 -2 0 -1 -3 -3 -3 0 0 8 43 0 13 0 36 0 0 0 0 0 0 0 0 0 0 0 0 0.57 0.03 21 P -1 -1 2 1 -3 3 2 -2 -1 -3 -3 0 -2 -4 5 0 -1 -3 -2 -3 0 0 16 8 0 28 13 0 0 0 0 0 0 0 36 0 0 0 0 0 0.71 0.04 22 T 0 -1 3 0 -1 0 0 -1 -1 -2 -2 0 -1 -2 -1 3 3 -2 -2 -1 1 1 20 1 0 1 1 1 0 1 1 1 0 1 1 38 29 0 1 1 0.32 0.03 23 D -1 -1 1 5 -3 0 3 -1 -1 -3 -3 0 -2 -3 -1 0 -1 -3 -2 -3 1 1 1 62 0 1 24 1 0 1 1 1 0 1 1 1 1 0 0 1 0.67 0.05 24 S 0 2 1 -1 -2 3 0 1 -1 -1 -2 0 -1 -2 -1 1 1 -2 -2 -1 1 18 7 1 0 25 1 11 0 7 1 1 0 1 1 15 8 0 0 1 0.18 0.02 25 T 0 -1 0 -1 -1 0 -1 2 -1 -1 -2 -1 -1 -2 1 2 2 -2 -2 -1 1 1 1 1 0 7 1 18 0 1 1 1 0 1 7 28 25 0 0 5 0.23 0.02 26 D -1 2 1 2 -2 0 0 0 -1 -2 -2 0 -1 -2 3 0 0 -2 -2 -2 1 17 7 20 0 1 5 6 0 1 5 1 0 1 17 9 8 0 0 1 0.27 0.02 27 N -1 0 5 1 -2 0 0 -1 0 -2 -2 0 -2 -2 -1 2 1 -3 -2 -2 1 5 60 1 0 1 1 1 0 1 1 1 0 1 1 16 7 0 0 1 0.46 0.05 28 N -1 -1 4 0 -2 1 1 0 0 -1 -1 0 -1 0 -1 0 0 -2 -1 0 1 1 38 1 0 7 11 5 0 1 1 1 0 5 1 8 1 0 0 17 0.19 0.03 29 Q -1 2 0 -1 -2 5 1 -2 0 -2 -1 1 0 -2 -1 0 -1 -2 -1 -2 1 11 1 1 0 68 1 1 0 1 8 1 0 1 1 1 1 0 0 1 0.51 0.06 30 N -1 1 4 1 -2 1 0 -1 0 -2 -2 0 -1 -2 -1 1 2 -2 -2 -2 1 7 41 5 0 7 1 1 0 1 1 1 0 1 1 7 21 0 0 1 0.32 0.03 31 G -1 4 0 -1 -2 0 -1 2 -1 -3 -2 1 -2 -2 -2 0 -1 -2 -2 -2 1 50 5 1 0 1 1 26 0 1 1 1 0 1 1 8 1 0 0 1 0.40 0.04 32 G 0 -2 1 -1 -2 -1 0 5 -1 -3 -3 -1 -2 -3 -2 0 -1 -2 -2 -3 1 1 11 1 0 1 6 70 0 1 1 1 0 1 1 1 1 0 0 1 0.68 0.04 33 R -1 6 0 -1 -3 1 0 -2 0 -3 -2 2 -1 -2 -2 -1 -1 -2 -2 -2 1 82 5 1 0 1 1 1 0 1 1 1 0 1 1 1 1 0 0 1 0.69 0.06 34 N -1 4 2 0 -2 0 0 -1 0 -2 -2 1 -1 -2 -1 1 0 -2 -1 -2 3 39 17 2 1 1 2 3 1 2 3 6 1 1 2 12 2 0 1 2 0.25 0.02 35 G 0 -1 2 0 -1 -1 -1 4 -1 -2 -2 -1 -1 -2 -1 0 -1 -1 -1 -2 3 2 19 2 1 2 3 44 1 2 4 2 1 2 2 3 2 1 1 3 0.31 0.02 36 A 3 2 -1 -1 -1 0 0 0 -1 -1 -1 0 -1 -1 0 0 0 -1 -1 -1 48 18 2 2 1 2 2 3 1 2 4 2 1 1 2 3 2 1 1 3 0.16 0.02 37 R -1 3 2 0 -2 4 1 -1 0 -2 -2 1 -1 -2 -1 0 -1 -2 -1 -2 2 30 14 1 0 38 1 2 0 1 2 1 0 1 1 2 1 0 1 1 0.37 0.04 38 P -1 -2 0 -1 -2 -1 -1 -2 -2 -2 -2 -1 -2 -3 7 0 -1 -3 -2 -2 2 1 5 1 0 1 1 2 0 1 2 1 0 1 70 7 1 0 1 1 1.28 0.05 39 K -1 1 0 -1 -3 1 0 -1 -1 -2 -2 5 -1 -3 1 0 -1 -2 -2 -2 1 1 1 1 0 4 1 1 0 1 1 75 0 1 7 1 1 0 0 1 0.48 0.05 40 Q -1 1 2 0 -2 4 1 -1 0 -2 -2 1 -1 -2 1 0 -1 -2 -1 -2 2 8 12 2 1 52 2 2 1 1 3 2 1 1 5 2 2 0 1 2 0.36 0.04 41 R -1 3 0 -1 -2 2 1 -2 -1 -2 -2 1 -1 -2 -1 0 2 -2 -2 -1 1 30 1 1 0 16 11 1 0 1 1 5 0 0 1 5 24 0 0 1 0.30 0.03 42 R 0 2 0 -1 -2 3 0 -1 -1 -2 -2 2 -1 -2 3 0 -1 -2 -1 -2 8 14 1 1 0 27 1 2 0 1 2 17 0 1 16 4 1 0 1 1 0.33 0.03 43 P 0 -2 -1 -2 -3 -2 -1 -2 -2 -3 -3 -1 -2 -4 7 -1 0 -4 -3 -2 9 0 3 0 0 0 0 0 0 0 0 0 0 0 79 0 6 0 0 0 1.60 0.08 44 Q 0 2 0 -1 -2 3 0 -2 -1 -2 -2 2 -1 -3 -1 1 1 -3 -2 -2 7 18 0 0 0 22 0 0 0 0 0 25 0 0 0 17 12 0 0 0 0.34 0.04 45 G 1 -2 -1 -2 -2 -1 -2 3 -2 -1 -2 -1 -1 -3 2 0 1 -3 -2 0 16 0 0 0 0 3 0 40 0 0 0 0 0 0 12 0 15 0 0 15 0.36 0.04 46 L 2 -1 1 -1 -1 1 -1 1 -1 0 0 -1 0 -2 -2 0 0 -3 -2 1 27 0 9 0 0 12 0 15 0 0 17 0 0 0 0 3 3 0 0 15 0.11 0.02 47 P -1 -2 -2 -2 -3 -1 -1 -2 -2 -3 -3 -1 -2 -4 7 1 0 -4 -3 -2 0 0 0 0 0 3 0 0 0 0 0 0 0 0 75 15 4 0 0 3 1.49 0.08 48 N -1 -1 4 0 -2 -1 -1 -1 -1 0 -2 -1 -1 -2 2 1 0 -3 -2 -1 1 1 43 1 0 1 1 1 0 10 1 1 0 1 14 19 1 0 0 4 0.33 0.04 49 N 0 -1 3 0 -2 1 0 2 -1 -2 -2 0 -2 -3 2 1 0 -2 -2 -2 1 1 29 1 0 11 1 19 0 1 1 1 0 1 13 13 7 0 0 1 0.32 0.03 50 T -1 -1 2 -1 -2 -1 -1 1 3 -2 -2 -1 -2 -1 -2 1 3 -1 3 -2 0 0 18 0 0 0 0 11 11 0 0 0 0 0 0 9 33 0 17 0 0.28 0.04 51 A 3 -2 -2 -2 -1 -2 -2 -1 -1 0 -1 -2 -1 0 -2 1 0 -1 3 2 41 0 0 0 0 0 0 2 0 0 0 0 0 0 0 9 0 0 22 26 0.25 0.06 52 S 1 -1 0 -1 -2 -1 -1 -1 -2 -3 -3 -1 -2 -3 -1 5 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.79 0.14 53 W -4 -4 -5 -5 -3 -3 -4 -3 -3 -4 -3 -4 -2 0 -5 -4 -3 11 1 -4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 3.17 0.22 54 F -3 -3 -4 -4 -3 -4 -4 -4 -1 -1 0 -4 -1 7 -4 -3 -3 0 3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 91 0 0 0 0 9 0 1.18 0.13 55 T 1 -1 0 -1 -2 4 0 -1 -1 -2 -2 0 -1 -3 -1 3 2 -3 -2 -2 7 0 0 0 0 34 0 0 0 0 0 0 0 0 0 35 23 0 0 0 0.42 0.08 56 A 2 -2 -1 -2 -2 -2 -2 4 -2 -3 -3 -1 -2 -3 1 1 -1 -3 -3 -2 34 0 0 0 0 0 0 49 0 0 0 0 0 0 7 10 0 0 0 0 0.58 0.07 57 L -2 -3 -4 -4 -2 -3 -4 -4 -4 4 3 -3 1 0 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 61 39 0 0 0 0 0 0 0 0 0 0.54 0.08 58 T -1 0 -1 -2 -2 0 -1 -2 -2 -1 -2 3 -1 -3 -2 0 4 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 34 0 0 0 0 59 0 0 7 0.45 0.09 59 Q 2 0 -1 -1 -3 5 2 -2 -1 -3 -3 1 -1 -3 -2 0 -1 -3 -2 -2 25 0 0 0 0 66 6 0 0 0 0 2 0 0 0 0 0 0 0 0 0.64 0.11 60 H -1 -1 0 -1 -2 -1 -1 -2 4 -1 0 -1 -1 4 -2 -1 0 0 1 -1 2 1 5 1 1 1 2 2 24 1 5 2 1 37 1 2 9 0 1 2 0.26 0.04 61 G 0 0 0 -1 -2 3 0 3 0 -2 -2 0 -1 -2 -1 0 -1 -1 -1 -2 2 2 4 2 1 37 2 33 1 2 3 2 1 1 2 2 2 0 1 2 0.33 0.04 62 K -1 1 0 -1 -2 1 0 -1 -1 -2 -2 5 -1 -2 -1 0 -1 -2 -2 -2 2 1 1 1 0 1 2 2 1 1 2 74 1 1 1 4 1 0 1 2 0.46 0.07 63 E 0 2 0 -1 -3 1 1 -2 -1 -2 -2 4 -2 -3 0 0 -1 -3 -2 -1 8 6 5 0 0 5 10 0 0 0 0 57 0 0 3 0 0 0 0 5 0.39 0.06 64 E -1 1 -1 2 -4 1 4 -2 -1 -3 -3 2 -2 -4 3 -1 -1 -3 -3 -3 0 6 0 10 0 0 43 0 0 0 0 25 0 0 16 0 0 0 0 0 0.58 0.07 65 L -2 -3 -3 -4 -2 -3 -3 -4 -2 1 3 -3 1 4 -3 -2 0 -1 1 0 0 0 0 0 0 0 0 0 0 0 58 0 0 35 0 0 6 0 0 0 0.51 0.08 66 R 0 2 3 0 -3 2 2 0 0 -3 -3 2 -2 -3 -2 0 0 -3 -2 -2 9 14 25 0 0 14 13 6 0 0 0 14 0 0 0 0 4 0 0 0 0.32 0.04 67 F -2 -3 -2 -3 -2 -3 -3 -3 -2 0 0 -3 -1 6 -3 1 0 0 2 -1 0 0 0 0 0 0 0 0 0 4 0 0 0 69 0 16 9 0 0 2 0.60 0.10 68 P 2 -2 -2 -2 -2 -2 -1 -2 -2 -2 -3 -1 -2 -3 7 0 -1 -4 -3 -1 26 0 0 0 0 0 0 0 0 0 0 0 0 0 65 3 0 0 0 4 1.28 0.10 69 R -1 2 -1 2 -4 3 4 -2 -1 -3 -3 1 -2 -4 2 -1 -1 -3 -2 -3 0 17 0 9 0 18 40 2 0 0 0 0 0 0 13 0 0 0 0 0 0.55 0.07 70 G 0 -3 -1 -2 -3 -2 -3 6 -3 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.36 0.12 71 Q -1 0 0 -1 -3 5 2 -2 0 -3 -3 0 -1 -3 -2 3 0 -3 -2 -3 0 0 0 0 0 59 7 0 0 0 0 0 0 0 0 34 0 0 0 0 0.63 0.11 72 G 0 -3 -1 -2 -3 -2 -3 6 -3 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.36 0.12 73 V -1 -3 -4 -4 -2 -3 -3 -4 -4 2 0 -3 0 -2 -1 -2 -1 -4 -2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 98 0.72 0.15 74 P -2 -3 -3 -2 -4 -2 -2 -3 -3 -4 -4 -2 -3 -4 8 -2 -2 -5 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.41 0.19 75 I -2 -3 -2 3 -2 -2 -1 -3 -3 4 1 -2 0 -1 -3 -2 -1 -3 -2 2 0 0 0 27 0 0 0 0 0 47 11 0 0 0 0 0 0 0 0 15 0.36 0.09 76 N 2 -1 5 0 -2 -1 -1 -1 -1 -3 -3 -1 -2 -3 2 1 -1 -4 -3 -2 30 0 55 0 0 0 0 0 0 0 0 0 0 0 9 6 0 0 0 0 0.59 0.12 77 T 0 -1 2 0 -2 1 2 -2 -1 -2 -2 1 -2 -1 2 1 1 -3 -1 -2 11 0 14 0 0 6 20 0 0 0 0 9 0 3 13 5 17 0 3 0 0.28 0.05 78 N -1 -1 5 0 -3 -1 -1 4 -1 -4 -4 1 -3 -4 -3 0 -1 -4 -3 -4 0 0 55 0 0 0 0 36 0 0 0 9 0 0 0 0 0 0 0 0 0.77 0.13 79 S -1 -2 -1 0 -2 -1 -1 -2 -2 2 1 0 0 -1 -2 1 0 -3 -2 2 0 0 0 9 0 0 0 0 0 23 14 9 0 2 0 19 0 0 0 25 0.13 0.06 80 G -1 0 -1 0 -3 -1 -1 2 -2 -3 -3 3 -2 -4 4 0 1 -4 -3 -3 0 0 0 6 0 0 0 19 0 0 0 34 0 0 29 3 10 0 0 0 0.57 0.10 81 P 2 -1 -1 -1 -2 -1 -1 -1 -2 -2 -2 1 -2 -3 4 1 1 -3 -2 -1 23 0 0 0 0 0 0 1 0 0 2 17 0 0 30 9 13 0 0 1 0.50 0.07 82 D 0 -2 1 4 -2 0 0 -1 -2 -3 -3 -1 -2 -3 -2 2 2 -4 -3 -2 8 0 5 38 0 4 0 1 0 0 0 0 0 0 0 27 17 0 0 0 0.50 0.13 83 D -2 0 -1 1 -4 5 3 -3 -1 -4 -3 1 -2 -1 -2 -1 -2 -3 0 -3 0 0 0 5 0 53 28 0 0 0 0 5 0 4 0 0 0 0 4 0 0.75 0.19 84 Q 1 0 1 -1 -3 6 1 -2 -1 -3 -1 0 -1 -4 -2 -1 -2 -3 -2 -3 14 0 8 0 0 68 4 0 0 0 5 0 0 0 0 0 0 0 0 0 0.78 0.21 85 I 0 -1 -2 -3 -3 -1 -2 -3 5 4 -1 2 -1 -2 -3 -2 -2 -3 -1 0 8 0 0 0 0 0 0 0 26 43 0 23 0 0 0 0 0 0 0 0 0.41 0.16 86 G -1 -3 -1 -2 -4 -3 -3 6 -3 -5 -5 -3 -4 -4 -3 -1 -3 -4 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.63 0.25 87 Y -3 -3 -3 -4 -4 -3 -3 -4 0 -3 -2 -3 -2 2 -4 -3 -3 1 8 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.96 0.33 88 Y -4 -4 -5 -6 -4 -4 -4 -4 -3 -4 -3 -4 -3 0 -5 -4 -4 12 2 -4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 95 5 0 3.43 0.40 89 R -2 3 4 -1 -3 -1 -1 -2 0 -2 -1 0 -2 0 -3 -1 -1 -2 4 -1 0 31 33 0 0 0 0 0 0 0 4 4 0 1 0 0 0 0 22 5 0.48 0.15 90 R -2 6 -1 -2 -3 0 1 -3 -1 -3 -3 1 -2 -3 -2 -1 -2 -3 -2 -3 1 77 1 1 0 0 11 1 0 1 1 3 0 0 1 1 1 0 0 1 0.95 0.18 91 A 0 -1 -1 -2 -3 5 0 -3 5 -2 -2 0 -1 -3 -2 -1 0 -3 -1 0 6 0 0 0 0 52 0 0 24 0 0 0 0 0 0 0 5 0 0 12 0.64 0.18 92 T 1 -1 3 1 -2 3 0 -2 -1 0 -2 -1 -1 -3 -2 0 1 -3 -2 -1 16 0 22 8 0 24 0 0 0 10 1 0 0 0 0 4 15 0 0 0 0.27 0.11 93 R -2 6 -1 -2 -4 0 0 -3 1 -4 -3 2 -2 -4 -3 -2 -1 -4 -2 -3 0 82 0 0 0 0 6 0 4 0 0 5 0 0 0 0 3 0 0 0 1.12 0.22 94 R -1 5 -1 -1 -2 0 0 -1 -1 -2 -2 2 -1 -2 -1 0 -1 -2 0 -2 3 54 1 2 1 1 2 2 1 2 3 10 1 1 2 8 2 0 3 2 0.45 0.08 95 V -3 -3 -3 -4 -3 -3 -3 -4 -1 1 0 -2 2 5 -4 -3 -2 4 4 0 0 0 0 0 0 0 0 0 0 10 0 2 10 48 0 0 0 6 22 4 0.78 0.17 96 R -2 5 1 -2 -4 1 0 -3 -1 -4 -3 4 -2 -4 -1 -1 -2 -4 -3 -3 0 43 8 0 0 4 0 0 0 0 0 43 0 0 2 0 0 0 0 0 0.78 0.17 97 G -1 1 -1 -2 -2 -1 -2 0 -2 -1 -1 0 3 -2 3 0 3 -3 -2 -1 0 10 0 0 0 0 0 7 0 3 0 4 19 0 18 3 35 0 0 0 0.38 0.13 98 G 1 1 -1 -2 -2 -1 -2 4 -2 -2 -2 -1 -2 -3 1 0 -1 -3 -3 1 13 13 0 0 0 0 0 41 0 0 0 2 0 0 9 6 0 0 0 16 0.39 0.10 99 D -2 1 1 4 -4 0 1 -2 -1 -3 -3 4 -2 -4 -2 0 -1 -4 -3 -3 0 8 8 34 0 0 5 0 0 0 0 40 0 0 0 2 0 0 0 0 0.57 0.13 100 G -1 -3 -1 -2 -3 -2 -3 6 -3 -4 -4 -2 -3 -3 -3 -1 -2 -3 -3 -3 1 1 0 1 0 0 1 91 0 1 1 1 0 0 1 1 1 0 0 1 1.31 0.19 101 K -1 1 2 -1 -3 4 0 2 -1 -3 -2 2 -1 -3 -1 0 -1 -2 -2 -2 1 7 11 1 0 33 1 20 0 1 2 16 0 1 1 1 1 0 1 1 0.36 0.09 102 M -2 5 -1 -2 -4 4 0 -3 -1 -2 -2 1 1 -3 -3 -1 -1 -3 -2 -2 0 57 0 0 0 28 0 0 0 3 0 0 6 0 0 0 3 0 0 3 0.76 0.18 103 K -1 2 -1 -2 -3 0 -1 -3 -2 0 -2 5 -1 -3 -2 -1 -1 -4 -2 2 0 10 0 0 0 0 0 0 0 5 0 64 0 0 0 0 0 0 0 21 0.57 0.17 104 E -2 -1 0 3 -4 4 3 -2 -1 -3 -2 0 -2 -4 4 -1 -1 -4 -3 -3 0 0 3 20 0 29 20 0 0 0 4 0 0 0 22 1 0 0 0 0 0.65 0.14 105 L -1 -3 -4 -4 -2 0 -3 -4 -3 1 4 -3 1 -1 -3 -3 -2 -3 -2 2 4 0 0 0 0 5 0 0 0 0 69 0 0 0 0 0 0 0 0 21 0.54 0.15 106 S 1 -2 0 -2 -2 -2 -2 -2 -3 -2 1 -2 -1 -3 6 1 -1 -4 -3 -2 15 0 4 0 0 0 0 0 0 0 23 0 0 0 47 11 0 0 0 0 0.81 0.15 107 P -2 -2 -1 3 -4 -1 2 -3 -2 -4 -4 -1 -3 -4 6 0 -2 -4 -3 -3 0 0 0 21 0 0 16 0 0 0 0 0 0 0 52 10 0 0 0 0 1.17 0.18 108 R 1 5 1 -2 -3 0 -1 -2 -1 -3 -3 2 -2 -3 -2 -1 -1 -4 -3 -3 21 55 10 0 0 0 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0.65 0.16 109 W -4 -4 -5 -6 -4 -3 -4 -4 -4 -3 -1 -4 -2 -1 -5 -4 -4 11 0 -1 0 0 0 0 0 0 0 0 0 0 5 0 0 0 0 0 0 88 0 6 3.02 0.37 110 Y -3 -3 -2 -4 -4 -2 -3 -4 5 -2 -2 -3 -2 4 -4 -3 -3 0 7 -2 0 0 0 0 0 0 0 0 21 0 0 0 0 19 0 0 0 0 60 0 1.24 0.23 111 F -3 -4 -4 -5 -4 -4 -4 -4 -2 -1 -1 -4 -1 8 -5 -4 -3 0 2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 1.71 0.29 112 Y -3 -3 -3 -4 -4 -3 -3 -4 0 -3 -2 -3 -2 2 -4 -3 -3 1 8 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.96 0.33 113 Y -3 -3 -3 -4 -4 -3 -3 -4 0 -2 -2 -3 -2 3 -4 -3 -3 1 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 92 0 1.77 0.30 114 L -2 -3 -3 -3 -2 -2 -3 -4 -3 0 4 -3 1 -1 -3 -1 3 -3 -2 0 0 0 0 0 0 0 0 0 0 0 67 0 0 0 0 0 33 0 0 0 0.59 0.17 115 G -1 -3 -1 -2 -4 -3 -3 6 -3 -5 -5 -3 -4 -4 -3 -1 -3 -4 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.63 0.25 116 T -1 -2 -1 -2 -2 -2 -2 -3 -3 -2 -2 -2 -2 -3 -2 0 6 -4 -3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 1.24 0.28 117 G -1 -3 -1 -2 -4 -3 -3 6 -3 -5 -5 -3 -4 -4 -3 -1 -3 -4 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.63 0.25 118 P -2 -1 -3 -3 -4 -2 -2 -3 -3 -4 -4 -2 -4 -5 8 -2 -2 -5 -4 -4 0 4 0 0 0 0 0 0 0 0 0 0 0 0 96 0 0 0 0 0 2.41 0.30 119 E 1 -2 -1 -2 -3 -1 1 -3 7 -3 -3 -2 -2 1 -3 -1 -2 -2 2 -3 18 0 0 0 0 0 13 0 55 0 0 0 0 8 0 0 0 0 7 0 0.83 0.20 120 A 4 -2 -2 -2 -2 -1 -1 2 -2 -3 -3 1 -2 -3 -2 1 -1 -3 -3 -1 71 0 0 0 0 0 0 13 0 0 0 12 0 0 0 5 0 0 0 0 0.57 0.17 121 S -1 -2 2 5 -4 -1 0 1 -2 -4 -4 1 -3 -4 -2 0 -1 -4 -3 -4 3 0 11 59 0 0 0 11 0 0 0 10 0 0 0 6 0 0 0 0 0.76 0.16 122 L 2 -2 -2 0 -2 -2 -2 -2 -1 0 3 -2 0 -1 -3 -1 -1 -3 -2 0 34 0 0 7 0 0 0 0 1 0 55 0 0 0 0 2 0 0 0 0 0.34 0.14 123 P -1 2 2 -1 -3 2 1 -2 -1 -3 -3 3 -2 -4 3 0 -1 -4 -3 -3 0 9 16 0 0 12 5 0 0 1 0 32 0 0 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0.13 204 R -1 5 2 -2 -3 2 -1 -2 -1 -3 -2 1 -2 -3 -3 1 -1 -3 -2 -3 1 58 12 0 0 8 0 0 0 0 3 0 0 0 0 18 0 0 0 0 0.67 0.17 205 G 1 -2 1 -1 -2 1 -1 4 -2 -3 -3 -1 -2 -2 -2 2 1 -3 -2 -2 7 0 5 0 0 9 0 38 0 0 0 0 0 2 0 31 7 0 0 0 0.47 0.12 206 N 0 4 4 -1 -3 0 -1 -2 2 -3 -3 0 -2 -3 -2 1 1 -4 -2 -3 7 37 34 0 0 0 0 0 5 0 0 0 0 0 0 10 7 0 0 0 0.54 0.14 207 S 1 0 3 1 -2 2 0 -1 1 -3 -3 0 -2 -3 -1 3 0 -3 -2 -2 14 3 21 5 0 15 3 0 3 0 0 0 0 0 1 34 2 0 0 0 0.37 0.11 208 P -1 0 1 1 -3 1 -1 0 0 -3 -3 0 -2 -3 5 1 -1 -3 -2 -3 0 4 7 9 0 7 0 9 3 0 0 6 0 0 38 13 0 0 0 0 0.65 0.10 209 A 1 0 1 0 -2 1 -1 1 -1 -2 -2 1 -2 -1 -2 2 0 -3 -2 -1 17 5 7 3 0 6 0 12 0 0 0 8 0 4 0 30 4 0 0 3 0.21 0.07 210 R -1 4 2 2 -3 0 0 -2 -1 -3 -2 1 -2 -3 -2 1 -1 -3 -2 -3 1 47 12 13 0 0 0 0 0 0 3 5 0 0 0 16 0 0 0 0 0.48 0.12 211 M -1 -1 1 2 -2 1 1 0 1 -1 -2 0 0 -2 1 0 1 -3 -2 -1 3 0 6 16 0 6 10 7 7 4 1 3 6 0 7 3 17 0 0 4 0.15 0.05 212 A 1 -2 -1 1 -2 0 -1 1 -2 0 -1 -1 -1 -2 2 1 -1 -3 -2 1 20 0 0 9 0 3 0 14 0 6 5 2 0 0 13 12 0 0 0 14 0.17 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-3 -2 -1 42 7 0 0 0 0 4 0 0 0 0 19 0 0 0 5 24 0 0 0 0.33 0.11 338 I -1 -3 -2 -3 -2 -2 -3 -3 -2 3 0 -2 3 0 -3 -1 2 -2 2 2 0 0 0 0 0 0 0 0 0 40 0 0 12 0 0 0 23 0 12 13 0.36 0.12 339 K -1 3 -1 -2 -2 0 -1 -3 2 0 0 2 -1 -2 -2 -1 1 -3 0 1 0 26 0 0 0 0 0 0 7 0 6 20 0 0 0 0 12 0 5 23 0.23 0.09 340 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 3 -3 0 4 -3 -3 -1 -2 0 3 0 0 0 0 0 0 0 0 0 0 32 0 0 26 0 0 0 0 0 42 0.49 0.12 341 D -2 -2 0 5 -3 -1 0 -2 -2 -3 -4 0 -3 -4 5 0 -1 -4 -3 -3 0 0 0 47 0 0 0 0 0 0 1 5 0 0 39 5 0 0 0 0 1.02 0.15 342 D 0 3 0 0 -1 0 0 -2 -1 -3 -3 3 -2 -3 2 2 0 -3 -2 -2 5 22 0 7 2 0 0 0 0 0 1 25 0 0 9 26 0 0 0 0 0.35 0.09 343 K -1 -1 0 4 -3 0 1 -2 -1 -2 -3 2 -2 -3 -2 1 2 -3 -2 -2 0 0 2 37 0 0 5 0 0 0 1 21 0 0 0 6 26 0 0 0 0.45 0.10 344 D -2 -2 2 5 -3 -1 0 -2 2 -1 1 -1 -1 -2 -2 -1 0 -3 -2 -2 0 0 9 48 0 0 0 0 7 0 27 0 0 0 0 0 5 0 0 0 0.44 0.11 345 P -1 -3 -2 -2 -3 -2 -2 -3 -3 -4 -4 -2 -3 -4 7 1 -2 -5 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 86 14 0 0 0 0 2.03 0.24 346 Q -1 0 2 -1 -3 4 0 3 2 -3 -3 1 -2 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0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.34 0.01 400 D -1 -1 0 4 -3 0 3 -2 -1 -1 1 -1 0 -2 -2 -1 -1 -3 -2 -1 0 0 0 41 0 0 28 0 0 0 31 0 0 0 0 0 0 0 0 0 0.34 0.01 401 M -1 -2 -3 -3 -1 -2 -3 -3 -3 3 2 -2 3 0 -3 -2 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 31 14 0 27 0 0 0 0 0 0 28 0.30 0.01 402 D -2 -1 1 5 -4 0 3 -2 -1 -3 -3 0 -3 -4 -1 0 -1 -4 -3 -3 0 0 0 69 0 0 31 0 0 0 0 0 0 0 0 0 0 0 0 0 0.77 0.01 403 D -2 -1 5 4 -3 0 1 -1 0 -3 -4 0 -3 -3 -2 0 0 -4 -3 -3 0 0 59 41 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.68 0.01 404 F -1 -2 -3 -3 -2 -2 -3 -3 0 1 0 -3 0 4 -3 -2 -1 1 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 41 0 0 0 0 31 28 0.45 0.01 405 S 1 -1 0 -1 -1 0 0 -1 -1 -2 -2 0 -1 -2 -1 3 3 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 69 31 0 0 0 0.41 0.01 406 R -1 5 0 -1 -3 1 0 -2 0 -3 -2 3 -1 -3 -2 -1 -1 -3 -2 -2 0 65 0 0 0 0 0 0 0 0 0 35 0 0 0 0 0 0 0 0 0.60 0.00 407 Q -1 1 0 0 -3 5 2 -2 0 -3 -2 1 0 -3 -1 0 -1 -2 -1 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.64 0.00 408 L -1 -2 -3 -4 -1 -2 -3 -4 -3 2 4 -2 2 0 -3 -2 -1 -2 -1 1 0 0 0 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0 0 0 0 0 0 0 0 0 0 0 0 0.40 0.00 418 D -2 -2 1 6 -4 0 2 -1 -1 -3 -4 -1 -3 -4 -2 0 -1 -4 -3 -3 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.92 0.00 419 S 1 -1 1 0 -1 0 0 0 -1 -2 -2 0 -2 -2 -1 4 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.45 0.00 420 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 1 5 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.46 0.00 421 Q -1 1 0 0 -3 5 2 -2 0 -3 -2 1 0 -3 -1 0 -1 -2 -1 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.64 0.00 422 A 4 -1 -2 -2 0 -1 -1 0 -2 -1 -1 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.40 0.00 K Lambda Standard Ungapped 0.1282 0.3101 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1282 0.3101 PSI Gapped 0.0410 0.2670