Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 M -1 -2 -3 -3 -1 -1 -2 -3 -2 2 2 -2 5 0 -3 -2 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 0 0 0 68 0 0 0 0 0 0 32 0.29 0.01 2 A 4 -1 -1 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -2 -1 2 0 -3 -2 -1 82 0 0 0 0 0 0 0 0 0 0 0 0 0 0 18 0 0 0 0 0.39 0.01 3 A 3 -1 -2 -2 -1 1 -1 -1 -2 1 -1 -1 0 -2 -1 0 0 -3 -2 1 62 0 0 0 0 13 0 0 0 12 0 0 0 0 0 0 0 0 0 12 0.21 0.01 4 K 0 1 0 -1 -2 2 0 -2 -1 -1 -2 4 -1 -3 -1 1 0 -3 -2 0 0 0 0 0 0 11 0 0 0 0 0 56 0 0 0 21 0 0 0 12 0.29 0.02 5 V -1 -3 -3 -4 -2 -3 -3 -4 -3 2 2 -3 1 4 -3 -2 -1 -1 1 3 0 0 0 0 0 0 0 0 0 0 23 0 0 32 0 0 0 0 0 45 0.32 0.02 6 F -2 -3 -3 -3 -2 -3 -3 -4 -2 1 3 -3 1 3 3 -2 -2 -1 1 0 0 0 0 0 0 0 0 0 0 12 45 0 0 28 15 0 0 0 0 0 0.35 0.01 7 E -1 0 2 2 -3 1 3 1 -1 -3 -3 1 -2 -3 -1 1 1 -3 -2 -2 0 0 11 12 0 0 30 11 0 0 0 15 0 0 0 11 11 0 0 0 0.31 0.01 8 S -1 3 2 -1 -2 0 -1 1 -1 -2 -2 1 -2 -3 -2 1 0 -3 -2 -1 0 34 21 0 0 0 0 15 0 0 0 0 0 0 0 17 0 0 0 12 0.25 0.01 9 I -1 -3 -3 -3 -2 -2 -3 -4 -3 3 2 -2 1 0 3 -2 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 40 32 0 0 0 15 0 0 0 0 12 0.34 0.01 10 G 2 -2 -1 -2 -2 -1 -2 4 -2 -3 -3 -1 -2 -3 -2 0 1 -3 -3 -2 33 0 0 0 0 0 0 55 0 0 0 0 0 0 0 0 12 0 0 0 0.54 0.02 11 K -1 2 0 -1 -3 2 0 1 -1 -3 -3 4 -1 -3 -1 0 1 -3 -2 -2 0 12 0 0 0 11 0 15 0 0 0 51 0 0 0 0 11 0 0 0 0.35 0.02 12 F 1 -2 -2 -3 -2 -2 -2 1 -1 0 0 -2 1 2 -2 -1 -1 -1 2 1 21 0 0 0 0 0 0 15 0 0 0 0 11 17 0 0 0 0 12 23 0.14 0.01 13 G 3 -2 -1 -2 -1 -2 -2 4 -2 -1 -2 -1 -1 -2 -2 0 -1 -3 -2 0 45 0 0 0 0 0 0 39 0 0 0 0 0 0 0 0 0 0 0 15 0.38 0.02 14 L -2 -3 -4 -4 -2 -3 -3 -4 -3 2 3 -3 1 3 -3 -3 -1 -1 0 1 0 0 0 0 0 0 0 0 0 18 57 0 0 16 0 0 0 0 0 9 0.36 0.02 15 A 2 -1 -1 -2 -2 -1 -1 3 -2 -3 -3 1 -2 -3 3 0 -1 -3 -3 -2 32 0 0 0 0 0 0 33 0 0 0 16 0 0 19 0 0 0 0 0 0.45 0.02 16 L 0 -3 -3 -4 -1 -2 -3 -3 -3 2 3 -3 2 0 -3 -2 -1 -2 -1 2 8 0 0 0 0 0 0 0 0 19 57 0 0 0 0 0 0 0 0 16 0.32 0.02 17 A 2 -2 -1 -2 -1 -1 -1 4 -2 -2 -2 -1 -2 -3 -2 1 1 -3 -2 0 30 0 0 0 0 0 0 39 0 0 0 0 0 0 0 15 9 0 0 7 0.37 0.02 18 V -1 -3 -3 -3 -1 -3 -3 -4 -3 3 1 -3 1 -1 -3 -2 1 -3 -2 4 0 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 7 0 0 68 0.38 0.03 19 A 3 -2 -2 -2 -1 -2 -2 2 -2 2 0 -2 0 -2 -2 0 -1 -3 -2 1 48 0 0 0 0 0 0 17 0 28 7 0 0 0 0 0 0 0 0 0 0.21 0.02 20 G 2 -2 -1 -2 -2 -2 -2 4 -2 -2 -2 -2 -2 1 -2 0 0 -2 1 -2 22 0 0 0 0 0 0 54 0 0 0 0 0 8 0 0 8 0 8 0 0.46 0.02 21 G 1 -2 -1 -1 -2 -2 -2 5 -2 -3 -3 -1 -2 -3 -2 1 2 -3 -3 -2 7 0 0 0 0 0 0 63 0 0 0 0 0 0 0 8 22 0 0 0 0.62 0.03 22 V 0 -3 -3 -3 -1 -2 -3 0 -3 2 2 -2 1 -1 -3 -2 -1 -3 -2 3 7 0 0 0 0 0 0 8 0 8 37 0 0 0 0 0 0 0 0 40 0.24 0.02 23 V 1 -1 -3 -3 -1 -2 -2 -3 -3 2 2 -2 1 -1 -2 -1 -1 -3 -2 3 18 5 0 0 0 0 0 0 0 17 21 0 0 0 0 0 0 0 0 39 0.22 0.02 24 N -1 2 3 0 -3 3 1 0 0 -3 -3 1 -2 -3 -2 0 1 -3 -2 -3 0 14 30 0 0 31 5 5 0 0 0 5 0 0 0 0 10 0 0 0 0.39 0.04 25 S 0 -1 1 0 -2 0 1 -1 1 -3 -3 -1 -2 -2 -1 4 2 -3 0 -2 0 0 8 0 0 0 7 0 4 0 0 0 0 0 0 65 12 0 4 0 0.40 0.07 26 A 3 -1 -1 -1 -1 -1 -1 0 -2 -2 -2 -1 -2 -3 -1 3 1 -3 -2 -1 42 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 9 0 0 0 0.41 0.06 27 L -1 -3 -3 -4 -2 -2 -3 -4 -3 3 3 -3 4 0 -3 -2 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 16 41 0 22 0 0 0 0 0 0 22 0.39 0.05 28 Y -2 1 -2 -3 -3 -1 -2 -3 0 -1 -1 1 -1 4 -3 -2 -2 1 5 -1 0 12 0 0 0 0 0 0 0 0 0 12 0 30 0 0 0 0 41 4 0.54 0.07 29 N -1 -2 4 1 -2 -1 -1 -2 -1 2 -1 -1 -1 -2 -2 0 2 -4 -2 0 0 0 38 8 0 0 0 0 0 27 0 0 0 0 0 0 27 0 0 0 0.30 0.06 30 V -1 -3 -4 -4 -1 -3 -3 -4 -4 2 0 -3 0 -1 -3 -2 -1 -4 -2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.63 0.10 31 D -2 0 0 5 -4 1 3 -2 -1 -4 -4 3 -3 -4 0 -1 -1 -4 -3 -3 0 0 0 44 0 0 24 0 0 0 0 28 0 0 4 0 0 0 0 0 0.60 0.06 32 A 1 -2 -1 -1 -3 -1 2 5 -2 -4 -4 -1 -3 -4 -2 0 -2 -3 -3 -3 10 0 0 0 0 0 24 66 0 0 0 0 0 0 0 0 0 0 0 0 0.72 0.07 33 G -1 -3 -1 -2 -3 -2 -3 6 -1 -4 -3 -2 -3 -1 -3 -1 -2 -1 4 -3 0 0 0 0 0 0 0 76 0 0 0 0 0 0 0 0 0 0 24 0 0.90 0.08 34 H -2 0 0 0 -4 4 3 -2 6 -4 -3 1 -2 -3 -2 0 -2 -3 0 -3 0 0 0 0 0 27 26 0 40 0 0 4 0 0 0 3 0 0 0 0 0.67 0.09 35 R -2 7 -1 -2 -4 0 -1 -3 -1 -4 -3 2 -2 -4 -3 -1 -2 -4 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.17 0.14 36 A 5 -2 -2 -2 -1 -1 -2 2 -2 -2 -2 -1 -2 -3 -2 1 -1 -3 -3 -1 87 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0.59 0.10 37 V -1 -3 -4 -4 -1 -3 -3 -4 -4 4 1 -3 0 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 31 0 0 0 0 0 0 0 0 0 69 0.55 0.09 38 I -1 -3 -3 -4 -2 -2 -3 -4 -3 4 1 -2 3 1 -3 -2 -1 -2 -1 3 0 0 0 0 0 0 0 0 0 42 7 4 14 8 0 0 0 0 0 25 0.34 0.06 39 F -3 -4 -4 -4 -3 -4 -4 -4 -2 -1 0 -4 -1 7 -4 -3 -3 0 3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 93 0 0 0 0 7 0 1.18 0.13 40 D -1 1 3 3 -3 0 0 2 1 -4 -4 0 -3 -3 -2 0 -1 -4 -2 -3 0 12 27 29 0 0 0 20 5 0 0 0 0 0 0 7 0 0 0 0 0.45 0.06 41 R -2 6 -1 -2 -4 0 -1 -3 -1 -3 0 1 -1 -3 -3 -2 -2 -3 -2 -3 0 88 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0.89 0.12 42 F -2 -3 -3 -3 -2 -3 -3 0 -3 2 2 -3 1 4 -3 -2 -2 -1 0 1 0 0 0 0 0 0 0 12 0 27 22 0 0 30 0 0 0 0 0 10 0.29 0.05 43 R -1 2 0 -1 -2 -1 0 1 0 0 -1 0 -1 -2 -2 1 1 -3 -2 1 0 23 3 0 0 0 5 16 4 0 0 0 0 0 0 11 9 0 0 29 0.13 0.04 44 G 0 -3 -1 -2 -3 -2 -3 6 -3 -3 -1 -2 -2 -3 -3 -1 -2 -3 -3 -3 0 0 0 0 0 0 0 88 0 0 12 0 0 0 0 0 0 0 0 0 1.02 0.10 45 V 1 -3 -3 -3 -1 -2 -3 -3 -3 3 1 -2 0 -1 -3 -1 -1 -3 -2 4 20 0 0 0 0 0 0 0 0 27 4 0 0 0 0 0 0 0 0 50 0.34 0.06 46 Q -1 3 -1 -1 -3 2 0 -2 -1 -2 -1 3 0 -3 2 0 -1 -3 -2 -2 0 20 0 0 0 17 0 0 0 0 8 33 3 0 12 8 0 0 0 0 0.37 0.05 47 D -1 -1 2 4 -3 1 2 -1 -1 -2 -3 0 -2 -3 -1 0 0 -3 -2 -2 2 1 12 41 0 4 16 1 0 1 2 5 0 1 1 5 5 0 1 1 0.41 0.04 48 I -1 1 0 0 -2 2 1 -1 0 -1 -1 2 -1 -2 -1 0 1 -2 -1 -1 2 9 5 6 1 14 11 2 1 7 6 17 1 1 2 2 10 0 1 2 0.12 0.01 49 V 0 -2 -2 -2 -1 -2 -2 -2 -2 2 1 -2 0 -1 1 -1 1 -2 -1 3 2 1 1 1 0 1 1 1 0 16 6 1 0 1 6 5 7 0 1 47 0.19 0.04 50 V -1 -1 -2 -2 -2 -1 -1 -2 -1 1 1 1 0 1 -2 -1 -1 0 4 2 2 1 1 1 0 1 1 1 0 1 10 13 0 5 1 1 1 0 23 35 0.15 0.04 51 G 0 -2 1 -1 -3 0 -2 5 -2 -4 -4 -1 -3 -4 3 0 -2 -3 -3 -3 8 0 7 0 0 4 0 62 0 0 0 4 0 0 15 0 0 0 0 0 0.72 0.07 52 E -1 -1 -1 0 -4 1 5 -3 -1 -4 -4 0 -3 -4 5 -1 -2 -4 -3 -3 0 0 0 0 0 0 68 0 0 0 0 0 0 0 32 0 0 0 0 0 0.99 0.11 53 G 0 -3 -1 -2 -3 -3 -3 6 -3 -5 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.36 0.13 54 T -1 -2 -2 -2 -2 -2 -2 -3 -3 2 2 -2 0 -1 -2 0 4 -3 -2 1 0 0 0 0 0 0 0 0 0 21 28 0 0 0 0 0 51 0 0 0 0.35 0.08 55 H -2 -1 2 -2 -4 -1 -1 -3 8 -3 -2 -2 -2 4 -3 -2 -2 -2 1 -3 0 0 10 0 0 0 0 0 61 0 0 0 0 29 0 0 0 0 0 0 0.87 0.13 56 F -3 -1 -4 -4 -3 -3 -4 -4 -2 1 1 -3 0 7 -4 -3 -3 0 2 -1 0 5 0 0 0 0 0 0 0 10 5 0 0 80 0 0 0 0 0 0 0.85 0.12 57 L -2 1 -3 -3 -2 -2 -2 -4 -3 4 2 0 2 0 -3 -2 -1 -3 -1 1 0 10 0 0 0 0 0 0 0 48 23 8 8 3 0 0 0 0 0 0 0.27 0.06 58 I -2 -4 -4 -4 -2 -3 -4 -4 -4 5 1 -3 1 1 -3 -3 -1 -3 -1 2 0 0 0 0 0 0 0 0 0 83 0 0 3 5 0 0 0 0 0 8 0.60 0.10 59 P -2 -3 -3 -2 -4 -2 -2 -3 -3 -4 -4 -2 -3 -5 8 -2 -2 -5 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.36 0.16 60 W -3 -4 -4 -5 4 -3 -4 -4 -3 2 0 -4 -1 2 -4 -3 -2 10 2 -1 0 0 0 0 11 0 0 0 0 20 3 0 0 10 0 0 0 52 3 0 1.34 0.12 61 V -2 -3 -4 -4 -2 -3 -3 -4 -3 2 3 -3 1 4 -3 -3 -2 -1 1 2 0 0 0 0 0 0 0 0 0 14 36 0 0 34 0 0 0 0 0 16 0.42 0.06 62 Q -2 0 0 3 -4 5 4 -2 -1 -4 -3 0 -2 -4 -2 -1 -1 -3 -3 -3 0 0 0 24 0 41 35 0 0 0 0 0 0 0 0 0 0 0 0 0 0.71 0.10 63 K -1 3 1 -1 -3 0 -1 -2 -1 -1 -2 3 -1 -2 -2 0 2 -2 2 0 0 20 9 0 0 0 0 0 0 0 0 31 0 0 0 0 20 0 10 10 0.25 0.06 64 P 2 -3 -3 -2 -2 -2 -2 -2 -2 -2 -2 -2 1 1 6 -1 -1 -3 -2 -2 24 0 0 0 0 0 0 0 0 0 0 0 9 11 56 0 0 0 0 0 1.01 0.10 65 I -1 -3 -3 -3 -2 -2 -2 -4 1 4 1 -3 1 0 -3 -2 -1 -2 0 3 0 0 0 0 0 0 3 0 6 46 11 0 0 0 0 0 0 0 5 30 0.33 0.06 66 I -2 -2 1 -1 -2 -2 -2 -3 -3 4 0 0 0 -1 -3 -2 -1 -3 -2 2 0 0 11 3 0 0 0 0 0 64 0 10 0 0 0 0 0 0 0 11 0.30 0.08 67 F -2 -3 -3 -4 -2 -3 -3 -4 0 2 0 -3 0 4 -3 -2 -2 0 5 2 0 0 0 0 0 0 0 0 0 11 0 0 0 22 0 0 0 0 39 28 0.54 0.08 68 D -3 -2 1 7 -4 -1 1 -2 -2 -4 -5 -1 -4 -4 -2 -1 -2 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.34 0.15 69 C -1 -3 -4 -4 2 -3 -3 -4 -3 3 3 -3 2 0 -3 -2 -1 -3 -2 3 0 0 0 0 5 0 0 0 0 31 29 0 10 0 0 0 0 0 0 26 0.37 0.06 70 R -2 7 -1 -2 -4 0 -1 -3 -1 -4 -3 2 -2 -4 -3 -2 -2 -4 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.18 0.15 71 S 2 -2 -1 -2 -1 -1 -1 -1 -2 -1 -2 -1 -1 -3 -1 2 4 -3 -2 1 27 0 0 0 0 0 0 0 0 0 0 0 0 0 0 18 44 0 0 11 0.35 0.07 72 R 0 4 -1 -2 -3 2 0 -2 -1 -2 -2 3 -1 -3 -2 0 0 -3 -2 -1 11 36 0 0 0 12 0 0 0 0 0 25 0 0 0 3 4 0 0 9 0.37 0.06 73 P -1 -3 -2 -2 -2 -2 -2 -3 -3 -1 -2 -2 -2 -3 7 1 1 -4 -3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 61 11 9 0 0 19 1.13 0.10 74 R -2 4 0 -2 -3 -1 -1 -3 2 -2 0 0 -1 0 -3 -1 0 0 5 -2 0 34 3 0 0 0 0 0 6 0 9 3 0 0 0 0 10 0 35 0 0.39 0.08 75 N -1 -1 4 3 -3 0 0 -1 -1 -2 -1 1 -2 -3 -2 0 0 -4 -2 -2 4 0 31 28 0 3 0 0 0 0 8 12 0 0 0 6 6 0 0 3 0.33 0.05 76 V -1 -3 -3 -3 -2 -3 -2 -4 -3 4 1 -3 0 1 -3 -2 -1 -3 -1 4 0 0 0 0 0 0 3 0 0 40 0 0 0 6 0 0 0 0 0 51 0.44 0.08 77 P 0 0 1 -1 -3 -1 0 -2 -2 -3 -3 0 -2 -4 6 1 0 -4 -3 -2 8 3 8 0 0 0 8 0 0 0 0 3 0 0 46 19 4 0 0 0 0.82 0.07 78 V 0 -2 -1 -2 -1 -1 -1 -2 -2 0 -1 -1 2 -2 -2 3 2 -3 -2 2 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 50 14 0 0 26 0.29 0.08 79 I -1 -1 0 0 -2 2 0 -3 -2 2 0 0 0 -2 2 -1 1 -3 -2 1 0 0 3 8 0 23 0 0 0 24 9 3 0 0 10 0 10 0 0 9 0.16 0.04 80 T 0 -2 -1 -2 -1 -1 -1 -2 -2 1 -1 -1 -1 -2 -2 2 5 -3 -2 0 0 0 0 0 0 0 0 0 0 11 0 0 0 0 0 15 74 0 0 0 0.55 0.11 81 G 0 -2 -1 -2 -2 -2 -2 5 -2 0 0 -2 -1 -2 -2 -1 -1 -2 -2 -1 1 1 1 1 0 1 1 63 0 10 13 1 0 1 1 1 1 0 1 1 0.50 0.05 82 S 0 -1 0 -1 -1 -1 -1 -1 -1 -2 -2 -1 -1 -2 -1 4 3 -2 -2 -1 1 1 1 1 0 1 1 1 0 1 2 1 0 1 1 55 29 0 1 1 0.39 0.07 83 K -1 3 0 -1 -4 1 0 -2 0 -3 -3 5 -2 -4 -2 -1 -1 -4 -2 -3 0 16 3 0 0 0 0 0 3 0 0 78 0 0 0 0 0 0 0 0 0.70 0.11 84 D -3 -2 1 7 -4 -1 1 -2 -2 -4 -5 -1 -4 -4 -2 -1 -2 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.34 0.16 85 L -2 -2 3 -2 -2 -2 -2 -3 -2 0 3 -2 1 -1 -3 0 -1 -3 -2 0 0 0 26 0 0 0 0 0 0 0 64 0 0 0 0 10 0 0 0 0 0.32 0.09 86 Q 0 0 -1 -2 -3 5 1 -2 -1 -1 -2 0 -1 -3 -2 -1 -1 -3 -2 2 9 0 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 0 0 27 0.50 0.12 87 N -1 -2 2 -2 -2 -1 -2 -2 -2 0 0 -1 5 -2 1 0 2 -3 -2 1 0 0 20 0 0 0 0 0 0 0 0 0 38 0 9 0 24 0 0 9 0.30 0.10 88 V -1 -3 -4 -4 -1 -3 -3 -4 -4 2 0 -3 0 -2 -3 -2 -1 -4 -2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.69 0.14 89 N -1 2 5 0 -3 0 0 -1 0 -3 -3 2 -2 -3 -2 2 0 -4 -2 -3 0 9 47 0 0 0 0 0 0 0 0 24 0 0 0 18 3 0 0 0 0.49 0.09 90 I -1 -3 -4 -4 -2 -3 -3 -4 -4 4 2 -3 1 -1 -3 -3 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 47 14 0 0 0 0 0 0 0 0 39 0.48 0.08 91 T -1 -2 3 3 -2 -1 -1 1 -1 -2 -3 -1 -2 -3 -2 1 4 -4 -3 -2 0 0 20 19 0 0 0 12 0 0 0 0 0 0 0 4 44 0 0 0 0.41 0.08 92 L 2 -2 -3 -3 2 -2 -2 -2 -3 1 3 -2 1 -1 -2 -1 -1 -2 -2 1 36 0 0 0 5 0 0 0 0 3 52 0 0 0 0 0 0 0 0 3 0.29 0.07 93 R -1 5 -2 -3 -3 0 -1 -3 -2 0 -1 1 -1 -3 -3 -2 -1 -3 -2 2 0 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 36 0.56 0.11 94 I -1 -3 -4 -4 -1 -3 -3 -4 -4 3 1 -3 0 -1 -3 -2 -1 -3 -2 5 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 80 0.59 0.11 95 L -2 -3 -3 -4 -2 -2 -3 -4 -1 0 4 -3 2 1 -4 -3 -2 0 5 0 0 0 0 0 0 0 0 0 0 0 60 0 4 0 0 0 0 0 36 0 0.56 0.10 96 F -1 -2 -2 -3 -2 -2 -2 -3 2 -1 -1 -2 -1 5 -3 1 1 0 4 -2 0 0 0 0 0 0 0 0 9 0 0 0 0 42 0 18 11 0 20 0 0.45 0.09 97 R -2 6 -1 -2 -4 0 -1 -3 -1 -4 -3 3 -2 -4 -3 -1 -2 -4 -2 -3 0 87 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 1.02 0.14 98 P -1 -3 -3 -2 -3 -2 -2 -3 -3 -2 -3 -2 -2 -4 8 -2 -2 -4 -3 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 83 0 0 0 0 17 1.74 0.15 99 V -1 -2 0 1 -2 -1 0 -3 -2 2 0 -1 2 -1 -2 -1 -1 -3 -2 2 0 0 8 9 0 0 10 0 0 22 2 3 9 0 0 4 0 0 0 31 0.12 0.04 100 A 2 -2 -1 1 -1 -1 -1 0 -2 0 -1 -1 -1 -2 2 0 1 -3 -2 2 33 0 0 9 0 0 0 5 0 0 0 0 0 0 10 0 10 0 0 30 0.18 0.05 101 S 0 -1 0 2 -2 0 1 -1 0 -1 -2 1 -1 -2 -1 2 1 -3 -2 0 2 0 0 16 0 2 7 3 3 0 3 8 0 0 0 33 9 0 0 12 0.18 0.04 102 Q 0 2 0 0 -2 4 2 -2 2 -2 -2 1 0 -3 -1 0 -1 -2 -1 -2 12 14 1 1 0 38 16 1 7 1 1 1 3 1 1 1 1 0 0 1 0.34 0.06 103 L -1 -2 -2 -2 -1 -2 -2 -3 -2 1 3 -2 1 0 -2 -2 -1 -2 -1 2 2 1 1 1 0 1 1 2 1 1 62 1 1 1 1 2 1 0 1 19 0.27 0.05 104 P -1 -1 -1 -1 -2 -1 -1 -2 -2 -2 -2 1 -2 -3 6 -1 1 -3 -2 -1 2 1 1 1 0 1 1 2 1 1 2 10 1 1 58 2 10 0 1 5 0.98 0.07 105 R 0 2 2 0 -2 1 2 -1 1 -2 -2 2 -1 -1 -1 1 0 -2 0 -2 6 14 13 1 0 5 16 1 3 1 1 16 0 3 1 8 3 0 5 1 0.19 0.02 106 I 0 -2 -2 -3 -1 -2 -2 -3 -2 4 1 -2 2 0 -2 -2 -1 -2 1 2 10 1 1 1 0 1 1 1 0 52 1 1 7 1 1 1 1 0 9 11 0.23 0.06 107 F -2 -3 -3 -4 -2 -2 -3 -4 0 2 0 -3 -1 4 -3 -2 -2 1 6 1 0 0 0 0 0 0 0 0 0 18 0 0 0 18 0 0 0 0 50 10 0.60 0.09 108 T -1 2 -1 -2 -2 2 0 -2 -1 0 1 0 2 -2 -2 0 1 -2 -1 0 1 21 1 1 0 17 1 1 0 1 14 1 9 0 1 4 17 0 0 11 0.14 0.04 109 S 1 0 1 0 -2 0 1 1 -1 -1 -2 0 -1 -2 -1 2 2 -2 -2 -1 10 7 9 1 0 1 10 11 0 3 1 4 0 0 1 19 22 0 0 1 0.17 0.03 110 I -1 -2 -2 -3 -1 -2 -2 -3 -3 2 3 -2 1 0 -2 -2 1 -2 -1 2 1 1 1 1 0 1 1 1 0 18 44 1 0 0 1 1 10 0 0 20 0.25 0.04 111 G 0 -2 -1 -1 -2 -1 -2 5 -2 -3 -3 -1 -2 -3 -2 1 -1 -2 -2 -2 2 1 1 1 0 1 1 71 0 1 2 1 0 1 1 10 1 0 1 1 0.71 0.07 112 E -1 0 1 0 -2 3 3 -1 -1 -1 1 0 0 -2 -2 -1 -1 -2 -2 -1 1 1 10 1 0 21 30 4 0 1 24 4 0 0 1 1 1 0 0 1 0.22 0.05 113 D 0 -1 2 5 -3 0 1 -1 -1 -3 -3 -1 -3 -3 -1 0 -1 -3 -3 -3 11 1 13 61 0 1 6 1 0 1 1 1 0 1 1 1 1 0 0 1 0.62 0.08 114 Y -2 -2 -2 -3 -2 -2 -2 -3 1 -2 -1 -2 -1 2 -3 -1 1 3 7 -1 1 1 1 1 0 1 1 1 0 1 1 1 0 1 1 1 11 3 74 1 0.85 0.12 115 D -1 0 0 5 -3 0 2 0 -1 -2 -3 0 -2 -3 -1 0 -1 -3 -2 -2 5 3 1 51 0 1 18 4 0 1 2 1 0 1 1 6 1 0 1 1 0.47 0.05 116 E -1 -1 -1 1 -3 2 5 -2 0 -3 -2 0 -2 -2 -1 1 -1 -2 1 -2 1 1 1 1 0 9 61 1 0 1 1 1 0 1 1 11 1 0 10 1 0.49 0.08 117 R 0 4 -1 -1 -2 0 0 -2 0 -2 -2 1 -1 -1 -1 0 1 -1 1 -1 11 47 1 1 0 1 1 2 0 1 2 6 1 1 1 2 11 0 9 1 0.29 0.05 118 V 0 -1 -2 -2 -1 -1 -1 -2 -2 2 0 0 0 -1 -1 -1 0 -2 -1 3 10 1 1 1 0 1 1 2 0 13 2 11 1 1 1 2 1 0 1 49 0.15 0.04 119 L -1 -2 -2 -2 -1 -2 -2 -2 -2 2 3 -2 1 0 -2 -1 0 -2 -1 1 2 1 1 1 0 1 1 2 0 10 62 1 1 1 1 2 10 0 1 1 0.25 0.05 120 P 0 -1 -1 -1 -2 -1 -1 -1 -2 -1 0 -1 -1 -2 6 -1 -1 -2 -2 -1 11 2 1 2 1 1 2 2 1 2 13 2 1 1 52 2 2 0 1 2 0.79 0.05 121 S 1 -1 2 0 -1 1 0 -1 -1 -2 -2 0 -1 -2 -1 3 1 -2 -2 -1 12 1 10 1 0 9 1 2 0 1 2 1 1 1 1 52 1 0 1 1 0.29 0.05 122 I -1 -2 -2 -3 -2 1 -2 -3 -2 4 2 -2 1 -1 -2 -2 -1 -2 -1 2 1 1 1 1 0 10 1 1 0 57 22 1 0 1 1 1 1 0 0 1 0.28 0.06 123 T 2 -2 -1 -2 1 -1 -1 1 -2 1 -1 -1 -1 -2 -1 1 2 -2 -2 1 21 1 1 1 3 1 1 14 0 10 1 1 0 1 1 10 18 0 0 16 0.13 0.03 124 T -1 0 4 0 -2 3 0 -1 2 -2 -2 0 -1 -3 0 0 1 -3 -2 -2 1 1 40 1 0 27 1 1 5 1 1 1 0 1 3 1 15 0 0 1 0.39 0.07 125 E -1 -1 0 1 -2 1 4 -2 -1 -2 -2 0 -2 -2 -1 0 2 -2 -2 -2 2 1 1 5 0 1 52 1 0 1 2 1 0 1 1 1 27 0 1 1 0.41 0.07 126 I 0 -2 -1 -2 -1 -1 -2 -2 -2 2 0 -1 0 -1 -1 0 3 -2 -1 3 2 1 1 1 0 1 1 1 0 11 2 1 0 1 1 1 36 0 1 37 0.22 0.05 127 L -2 -2 -3 -3 -2 -2 -3 -4 -3 1 4 -3 2 0 -3 -3 -1 -2 -1 1 1 0 0 1 0 0 1 1 0 0 87 1 0 0 0 1 1 0 0 5 0.52 0.09 128 K -1 4 -1 -1 -3 1 0 -2 -1 -3 -3 4 -2 -3 -2 -1 -1 -3 -2 -3 1 37 0 1 0 0 1 1 0 0 1 55 0 0 0 1 1 0 0 1 0.61 0.09 129 S 3 -1 0 -1 -1 -1 -1 0 -2 -2 -2 -1 -1 -2 -1 3 2 -3 -2 -1 37 0 0 1 0 0 1 4 0 0 1 1 0 0 0 42 10 0 0 1 0.35 0.07 130 V -1 -3 -3 -3 -1 -2 -3 -3 -3 4 1 -3 0 -1 -2 -2 -1 -3 -2 4 1 0 0 1 0 0 1 1 0 33 1 1 0 0 0 1 1 0 0 59 0.42 0.08 131 V -1 -3 -3 -3 -1 -2 -3 -3 -3 3 1 -2 1 -1 -2 -2 -1 -3 -1 4 1 0 0 1 0 0 1 1 0 27 11 1 0 0 0 1 1 0 0 55 0.37 0.07 132 A 4 -2 -1 -2 -1 -1 -2 4 -2 -2 -2 -1 -2 -3 -1 0 -1 -3 -2 -1 55 0 0 1 0 0 1 37 0 0 1 1 0 0 0 1 1 0 0 1 0.50 0.08 133 R -1 2 0 -1 -3 5 1 -2 0 -3 -3 2 -1 -4 -2 1 1 -3 -2 -2 0 13 2 0 0 55 0 0 0 0 0 9 0 0 0 9 10 0 0 0 0.54 0.10 134 F 1 -2 -3 -3 -2 -2 -3 -3 3 -1 0 -2 2 5 -3 -2 -2 0 3 -1 17 0 0 0 0 0 0 0 10 0 0 0 9 52 0 0 0 0 12 0 0.50 0.09 135 D -2 -1 4 4 -3 0 2 -2 3 -3 -4 -1 -3 -3 -2 0 1 -4 -2 -3 0 0 36 28 0 0 17 0 9 0 0 0 0 0 0 0 10 0 0 0 0.54 0.08 136 A 4 -2 -3 -3 -1 -2 -2 -1 -3 0 2 -2 0 -1 -2 0 -1 -3 -2 0 64 0 0 0 0 0 0 0 0 0 36 0 0 0 0 0 0 0 0 0 0.36 0.09 137 G 0 -2 0 4 -2 -1 0 2 0 -3 -3 -1 -3 -3 -2 3 0 -4 -3 -3 5 0 0 35 0 0 0 16 4 0 0 0 0 0 0 37 3 0 0 0 0.44 0.07 138 E -1 0 -1 1 -4 4 5 -3 1 -4 -3 0 -2 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 29 68 0 3 0 0 0 0 0 0 0 0 0 0 0 0.83 0.12 139 L -2 -3 -4 -4 -2 -3 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -2 2 0 0 0 0 0 0 0 0 0 10 69 0 4 0 0 0 0 0 0 17 0.49 0.08 140 I -2 -3 -4 -4 -2 -3 -4 -4 -4 4 3 -3 1 0 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 55 45 0 0 0 0 0 0 0 0 0 0.53 0.09 141 T 0 -2 2 -1 -2 -1 -1 -2 -2 -2 -2 -1 -2 -3 -2 3 5 -3 -2 -1 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 27 64 0 0 0 0.55 0.11 142 Q -1 0 0 2 -4 5 3 -2 0 -4 -3 2 -2 -4 -2 -1 -1 -3 -2 -3 0 0 0 10 0 55 26 0 0 0 0 9 0 0 0 0 0 0 0 0 0.69 0.11 143 R -2 7 -1 -2 -4 0 -1 -3 -1 -3 -3 2 -2 -3 -2 -1 -2 -3 -2 -3 1 91 0 1 0 0 1 1 0 0 1 1 0 0 0 1 1 0 0 1 0.96 0.13 144 E 0 -1 0 3 -3 1 4 -2 -1 -3 -3 0 -2 -3 2 0 -1 -3 -2 -2 7 0 0 18 0 4 56 1 0 0 1 1 0 0 9 1 1 0 0 1 0.56 0.07 145 L 0 1 -1 -1 -2 2 0 -2 0 -1 -1 3 0 -1 -2 0 -1 -2 1 0 8 3 0 1 0 19 1 1 3 3 5 30 3 0 0 3 1 0 10 10 0.15 0.04 146 V -1 -3 -3 -3 -1 -2 -3 -3 -3 3 2 -2 1 -1 -2 -2 -1 -3 -1 4 1 0 0 1 0 0 1 1 0 22 18 1 0 0 0 1 1 0 0 53 0.35 0.06 147 S 0 -1 4 0 -2 0 -1 -1 -1 -3 -3 -1 -2 -3 -1 4 1 -3 -2 -2 1 0 27 1 0 0 1 1 0 0 1 1 0 0 0 65 1 0 0 1 0.50 0.10 148 R 1 3 -1 -2 -2 1 -1 -2 -1 -1 0 1 2 -2 -2 1 -1 -3 -2 0 22 31 0 0 0 9 0 0 0 0 6 3 12 0 0 9 0 0 0 8 0.20 0.05 149 Q -1 1 -1 1 -3 3 2 -3 -1 -1 1 2 0 -2 -2 -1 -1 -3 -2 -1 0 6 0 10 0 22 12 0 0 0 27 23 0 0 0 0 0 0 0 0 0.24 0.06 150 V -1 -3 -3 -4 -1 -2 -3 -4 -3 3 2 -3 2 0 -3 -2 -1 -3 -2 3 4 0 0 0 0 0 0 0 0 33 26 0 10 0 0 0 0 0 0 27 0.37 0.06 151 S -1 4 -1 -2 -3 2 0 -2 -1 -2 -1 2 -1 -1 -2 1 -1 -3 -2 -2 0 41 0 0 0 17 0 0 0 0 9 10 0 3 0 20 0 0 0 0 0.37 0.07 152 D -1 2 0 2 -3 2 3 -2 -1 0 -2 2 -1 -3 -2 -1 -1 -3 -2 -1 0 15 0 16 0 14 24 0 0 10 0 18 0 0 0 0 0 0 0 4 0.32 0.05 153 D 0 -1 0 2 -2 -1 1 -2 -2 2 -1 -1 -1 -2 -2 1 1 -3 -2 0 6 3 5 13 0 0 14 0 0 35 0 0 0 0 0 15 7 0 0 0 0.13 0.05 154 L -2 -3 -4 -4 -2 -3 -4 -4 -3 3 4 -3 2 0 -3 -3 -2 -2 -2 1 0 0 0 0 0 0 0 0 0 17 80 0 0 0 0 0 0 0 0 3 0.58 0.09 155 T -1 -1 0 4 -2 -1 0 -2 -2 1 -1 -1 1 -2 -2 0 3 -3 -2 0 0 4 0 36 0 0 0 0 0 12 0 0 6 0 0 2 32 0 0 8 0.29 0.07 156 E -1 2 -1 1 -4 2 5 -3 -1 -3 -2 2 -2 -3 -2 -1 0 -3 -2 -2 0 12 0 3 0 3 60 0 0 0 2 13 0 0 0 0 5 0 0 3 0.54 0.09 157 R 1 5 -1 -1 -3 1 2 -2 -1 -3 -3 1 -2 -3 -2 -1 -1 -3 -2 -2 19 64 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0.61 0.10 158 A 4 -2 -1 -2 -1 -1 -1 -1 -2 -1 -2 -1 -1 -2 -1 1 3 -3 -2 -1 55 0 0 1 0 0 1 1 0 0 1 1 0 0 0 1 37 0 0 1 0.39 0.08 159 A 1 0 2 2 -2 0 1 -1 -1 -2 -2 2 -2 -3 -1 1 0 -3 -2 -2 18 3 11 19 0 0 10 1 0 0 4 22 0 0 0 5 3 0 0 1 0.22 0.03 160 T 0 0 1 2 -3 1 2 -2 -1 -3 -3 0 -2 -3 4 0 0 -3 -2 -2 10 3 7 15 0 7 15 1 0 0 1 6 0 0 27 1 5 0 0 1 0.46 0.04 161 F -3 -3 -3 -4 -3 -3 -3 -3 -2 -1 -1 -3 -1 6 -4 -3 -3 9 2 -2 1 0 0 1 0 0 1 1 0 0 1 1 0 55 0 1 1 36 0 1 1.22 0.12 162 G -1 -2 3 0 -3 -1 -1 5 0 -3 -3 -1 -3 -3 -2 0 -1 -3 -2 -3 1 0 29 3 0 0 1 52 3 0 1 1 0 0 0 7 1 0 0 1 0.59 0.07 163 L -1 -3 -3 -3 -1 -3 -3 -3 -3 4 2 -3 1 0 -3 -2 -1 -2 -1 2 1 0 0 1 0 0 1 1 0 62 16 1 0 3 0 1 1 0 0 12 0.39 0.07 164 I 0 2 -1 -1 -2 0 0 -2 -1 1 1 2 0 -2 -2 -1 -1 -3 -2 0 10 12 0 1 0 0 6 1 0 17 13 30 0 0 0 1 1 0 0 7 0.12 0.03 165 L -1 -2 -3 -3 -1 -2 -3 -3 -3 2 3 -2 1 0 -3 -2 -1 -2 -1 2 1 0 0 1 0 0 1 1 0 10 55 1 0 0 0 1 1 0 0 28 0.35 0.06 166 D -1 -1 0 5 -3 0 3 -2 -1 -3 -3 -1 -2 -3 -1 0 1 -3 -3 -2 1 0 0 50 0 0 25 1 0 0 1 1 0 0 0 1 18 0 0 1 0.58 0.08 167 D 1 1 0 5 -3 0 1 -1 -1 -3 -3 1 -2 -3 -2 0 -1 -3 -3 -2 18 10 0 55 0 0 1 1 0 0 1 10 0 0 0 1 1 0 0 1 0.49 0.07 168 V -1 -3 -3 -3 -1 -2 -3 -3 -3 3 0 -2 0 -1 -2 -2 -1 -3 -2 5 1 0 0 1 0 0 1 1 0 9 1 1 0 0 0 1 1 0 0 82 0.48 0.10 169 S 1 -1 0 0 -2 0 3 -1 -1 -3 -3 0 -2 -3 -1 3 0 -3 -2 -2 15 0 0 1 0 0 37 1 0 0 1 1 0 0 0 41 1 0 0 1 0.38 0.07 170 L -1 -3 -3 -3 -1 -3 -3 -3 -3 4 2 -3 1 0 -3 -2 -1 -2 -1 2 1 0 0 1 0 0 1 1 0 59 24 1 0 0 0 1 1 0 0 10 0.39 0.07 171 T -1 2 0 -1 -2 0 -1 -2 -1 -2 -2 3 -1 -3 -1 0 4 -3 -2 -1 1 10 0 1 0 0 1 1 0 0 1 27 0 0 0 1 55 0 0 1 0.39 0.08 172 H -1 -1 1 3 -3 0 2 0 5 -3 -3 -1 -2 -2 -2 -1 -1 -3 0 -3 1 0 5 27 0 0 19 7 29 0 1 1 0 0 0 1 3 0 3 1 0.44 0.06 173 L -1 -2 -3 -3 -1 -2 -3 -3 -3 2 3 -2 2 0 -3 -2 -1 -2 -1 3 1 0 0 1 0 0 1 1 0 10 45 1 8 0 0 1 1 0 0 31 0.32 0.05 174 T 0 1 1 1 -2 1 2 -1 -1 -2 -2 0 -2 -3 -1 2 2 -3 -2 -2 4 10 7 10 0 3 18 1 0 0 1 3 0 0 0 19 21 0 0 1 0.25 0.04 175 F -2 -2 -3 -3 -2 -2 -3 -3 -1 0 2 -3 0 5 1 -2 -2 0 3 -1 1 0 0 1 0 0 1 1 0 0 28 1 0 46 10 1 1 0 9 1 0.44 0.07 176 G 0 -2 -1 -1 -2 -1 -1 4 -2 -3 -3 -1 -2 -3 5 1 -1 -3 -3 -3 1 0 0 1 0 0 1 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56 8 1 1 0 5 1 4 4 1 2 4 7 1 1 3 1 0 1 1 0.22 0.05 186 K -1 2 -1 -1 -3 1 0 -2 -1 -2 -2 5 -1 -3 -1 -1 -1 -3 -2 -2 1 9 1 1 0 1 1 1 0 1 2 74 0 1 1 1 1 0 1 1 0.52 0.08 187 Q -1 2 0 -1 -3 6 1 -2 0 -3 -2 1 -1 -3 -1 -1 -1 -2 -2 -2 1 9 1 1 0 73 1 1 0 1 2 1 0 1 1 1 1 0 1 1 0.66 0.10 188 V 0 -2 -2 -2 -1 -2 -2 -2 -2 3 0 -2 0 -1 -2 -1 0 -2 -1 4 10 1 1 1 0 1 1 1 0 20 2 1 0 1 1 1 1 0 1 55 0.25 0.05 189 A 4 -2 -2 -2 -1 -1 1 -1 -2 -1 -1 -1 1 -2 -1 0 -1 -3 -2 -1 74 1 0 1 0 0 9 1 0 1 1 1 8 0 1 1 1 0 0 1 0.38 0.09 190 Q 2 0 -1 -1 -2 5 1 -1 -1 -2 -2 0 -1 -3 -1 0 -1 -2 -2 -2 30 1 0 1 0 61 1 1 0 1 1 1 0 0 1 1 1 0 0 1 0.53 0.10 191 Q -1 0 -1 -1 -3 6 2 -2 0 -2 -2 1 2 -3 -2 -1 -1 -2 -2 -2 1 1 0 1 0 73 9 1 0 1 1 1 8 0 1 1 1 0 0 1 0.69 0.12 192 E -1 1 -1 2 -4 2 5 -3 -1 -3 -2 0 1 -3 -2 -1 -1 -3 -2 -3 0 9 0 8 0 8 66 0 0 0 0 0 9 0 0 0 0 0 0 0 0.63 0.10 193 A 5 -2 -2 -2 -1 -1 1 0 -2 -2 -2 -1 -1 -3 -1 1 -1 -3 -2 -1 83 0 0 0 0 0 9 1 0 0 1 1 0 0 0 1 1 0 0 1 0.48 0.10 194 E -1 1 -1 1 -4 3 5 -2 0 -3 -3 1 -2 -3 -1 -1 -1 -3 -2 -3 1 9 0 0 0 15 68 1 0 0 1 1 0 0 0 1 1 0 0 1 0.67 0.09 195 R 0 5 -1 -2 -3 0 0 -2 -1 -3 -2 2 -1 -3 -2 -1 -1 -2 -2 -2 11 67 1 1 0 1 1 1 0 1 2 7 0 1 1 1 1 0 1 1 0.56 0.08 196 A 4 -1 -1 -1 -1 -1 -1 0 -2 -1 -2 -1 -1 -2 -1 2 1 -2 -2 -1 62 1 1 1 0 1 1 1 0 1 2 1 0 1 1 13 11 0 1 1 0.33 0.06 197 R 0 4 0 -1 -2 1 0 -1 -1 -2 -2 3 -1 -2 -1 0 0 -2 -1 -2 5 36 1 1 1 7 2 2 1 1 2 25 1 1 1 2 8 0 1 2 0.31 0.04 198 F -1 -2 -2 -2 -2 -2 -2 -2 -1 1 0 -2 0 5 -2 -1 -1 0 3 0 3 2 2 2 1 2 2 3 1 11 3 2 1 49 2 3 2 0 8 2 0.30 0.04 199 V -1 -1 -1 -2 -1 -1 -1 -2 -1 2 1 -1 1 0 -1 -1 1 -1 1 2 3 2 2 2 1 2 2 3 1 14 21 2 1 1 2 3 11 0 7 21 0.07 0.01 200 V 0 -1 -2 -2 -1 -1 -1 -2 -2 2 1 -1 0 -1 -1 -1 0 -2 -1 3 3 2 2 2 1 2 2 3 1 2 12 2 1 1 2 3 2 0 1 57 0.16 0.04 201 E 1 0 0 1 -2 1 3 -1 -1 -1 -1 0 1 -2 -1 0 -1 -2 -1 -1 16 2 2 7 1 2 39 3 1 2 3 2 9 1 2 3 2 0 1 2 0.20 0.03 202 K -1 2 0 0 -2 1 1 -1 -1 -2 -2 4 -1 -2 -1 0 -1 -2 -1 -2 2 8 1 1 1 4 11 2 1 1 2 56 1 1 1 2 2 0 1 2 0.35 0.05 203 A 4 -1 0 -1 -1 -1 -1 0 -2 -2 -2 -1 -1 -2 -1 1 0 -2 -2 -1 76 1 4 1 0 1 1 1 0 1 2 1 0 1 1 4 1 0 1 1 0.39 0.07 204 E -1 1 0 2 -3 1 4 -2 -1 -2 -2 1 -2 -3 -1 0 -1 -2 -2 -2 2 6 1 10 0 1 55 1 0 1 5 11 0 1 1 1 1 0 1 1 0.43 0.06 205 Q -1 3 0 -1 -3 5 1 -2 0 -2 -2 1 0 -3 -1 -1 -1 -2 -2 -2 2 27 1 1 0 52 1 1 0 1 2 1 3 1 1 1 1 0 1 1 0.50 0.08 206 Q -1 -1 0 3 -3 3 3 -2 -1 -2 -1 0 0 -3 -2 -1 -1 -3 -2 -2 1 0 0 25 0 19 36 1 0 0 10 1 4 0 0 1 1 0 0 1 0.40 0.06 207 K 0 3 -1 -1 -2 2 0 -1 -1 -2 -2 4 -1 -3 -1 0 -1 -2 -2 -2 11 25 1 1 0 7 1 1 0 1 2 42 0 1 1 1 1 0 1 1 0.36 0.05 208 K -1 4 -1 -1 -3 2 0 1 -1 -1 -1 2 -1 -2 -1 -1 -1 -2 -2 -2 1 39 1 1 0 15 1 11 0 4 4 15 0 1 1 1 1 0 1 1 0.30 0.05 209 A 3 -1 -1 -1 -1 1 0 1 -1 -2 -2 -1 -1 -2 -1 2 0 -2 -2 -1 48 1 1 1 0 7 4 7 0 1 2 1 0 1 1 22 1 0 1 1 0.26 0.05 210 A 2 0 1 -1 -1 0 0 -1 -1 -1 -1 2 0 -1 -1 1 0 -2 -1 -1 36 1 7 1 0 1 1 1 0 4 2 29 3 4 1 6 1 0 1 1 0.16 0.04 211 I -1 -2 -3 -3 -1 -2 -2 -3 -3 4 1 -2 1 -1 -2 -2 -1 -2 -1 3 1 1 1 1 0 1 1 1 0 56 2 1 0 1 1 1 1 0 1 28 0.34 0.06 212 I -1 -2 -2 -2 -1 -2 -2 -3 -3 4 1 -2 1 -1 -2 -2 0 -2 -1 3 1 1 1 1 0 1 1 1 0 52 11 1 0 1 1 1 5 0 1 19 0.27 0.05 213 S 1 4 -1 -1 -2 2 1 -1 -1 -2 -2 1 -1 -3 -1 1 0 -3 -2 -2 19 40 0 1 0 10 10 1 0 0 1 3 0 0 0 7 4 0 0 1 0.33 0.05 214 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 -1 -3 -2 -1 91 0 0 1 0 0 1 1 0 0 1 1 0 0 0 1 1 0 0 1 0.57 0.11 215 E -1 0 -1 1 -4 3 5 -2 -1 -3 -3 0 -2 -3 -1 -1 -1 -3 -2 -3 1 0 0 1 0 13 79 1 0 0 1 1 0 0 0 1 1 0 0 1 0.78 0.11 216 G 0 -2 -1 -2 -3 -2 -2 6 -2 -4 -4 0 -3 -3 -2 -1 -2 -3 -3 -3 1 0 0 1 0 0 1 82 0 0 1 9 0 0 0 1 1 0 0 1 0.93 0.10 217 D -1 -1 -1 2 -3 1 5 -2 -1 -2 -1 0 -2 -3 -2 -1 -1 -3 -2 -2 1 0 0 11 0 0 72 1 0 0 10 1 0 0 0 1 1 0 0 1 0.61 0.09 218 S 2 1 -1 -2 -1 -1 -1 0 -1 -1 0 1 -1 -1 -1 1 0 -2 1 -1 39 9 0 1 0 0 1 4 0 0 11 10 0 0 0 14 1 0 9 1 0.14 0.04 219 K -1 2 0 0 -3 3 4 -2 0 -3 -2 2 -2 -3 -1 0 0 -3 -2 -2 3 14 0 1 0 17 38 1 0 1 1 18 0 0 1 1 3 0 0 1 0.43 0.06 220 A 4 -1 -1 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -2 -1 2 0 -3 -2 -1 68 1 0 1 0 0 1 1 0 1 1 1 0 0 1 23 1 0 0 1 0.43 0.08 221 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -2 -1 1 0 -3 -2 -1 91 1 0 1 0 0 1 1 0 1 1 1 0 0 1 1 1 0 0 1 0.55 0.10 222 E -1 1 -1 0 -3 3 2 -1 -1 -1 0 2 1 -2 -2 -1 -1 -2 -2 -1 1 5 0 4 0 21 21 4 0 1 12 18 10 0 1 1 1 0 0 1 0.22 0.04 223 L 0 -1 -2 -3 -1 -1 -2 -2 -2 2 3 0 2 0 -2 -1 -1 -2 -1 1 12 1 0 1 0 0 1 1 0 13 43 10 8 3 1 1 1 0 0 5 0.16 0.03 224 I -1 -2 -3 -2 -2 -2 0 -3 -3 4 2 -2 1 -1 -2 -2 -1 -2 -1 2 1 1 0 1 0 0 11 1 0 52 25 1 0 0 1 1 1 0 0 4 0.27 0.06 225 A 2 -2 0 -1 -1 -1 -1 3 -2 -2 -2 -1 -2 -3 -1 2 0 -3 -2 -2 32 1 4 1 0 0 1 31 0 1 1 1 0 0 1 26 1 0 0 1 0.37 0.05 226 N 1 0 1 2 -2 2 3 -1 -1 -2 -2 2 -2 -3 -1 0 -1 -3 -2 -2 21 1 5 11 0 14 25 1 0 1 1 18 0 0 1 1 1 0 0 1 0.29 0.04 227 S 3 -1 -1 1 -1 -1 -1 -1 2 -2 -2 -1 -1 -2 -1 1 1 -3 -1 -1 53 1 0 10 0 0 1 1 10 1 1 1 0 0 1 8 11 0 0 1 0.27 0.06 228 L -1 -2 -2 -3 -1 -2 -2 -3 -2 3 2 -2 2 1 2 -1 1 -2 -1 2 1 1 0 1 0 0 1 1 0 30 19 1 7 7 10 1 10 0 0 10 0.20 0.03 229 A 2 -1 -1 -1 -1 -1 -1 0 -2 1 0 1 1 -1 -1 0 -1 -2 -2 0 31 1 1 4 0 1 1 8 0 12 11 14 10 1 1 4 1 0 0 1 0.07 0.03 230 T 1 0 3 0 -2 1 0 0 -1 -2 -2 1 -2 -3 -1 2 1 -3 -2 -2 20 3 20 1 0 4 4 5 0 1 1 15 0 0 1 20 5 0 0 1 0.22 0.03 231 A 2 0 0 -1 -1 1 0 -1 -1 -1 -1 2 -1 -2 -1 1 0 -2 -1 -1 26 2 2 2 1 11 2 3 1 2 3 21 1 1 2 13 2 0 1 5 0.13 0.02 232 G 0 0 2 0 -2 -1 -1 3 -1 -2 -2 -1 -2 -2 0 2 0 -2 -2 -2 5 4 18 5 0 1 1 28 0 1 2 1 1 1 5 22 1 0 1 1 0.26 0.03 233 D -1 -1 0 2 -2 1 2 -1 -1 -2 -1 0 1 -2 3 0 -1 -2 -2 -2 2 1 1 18 1 8 25 5 1 1 2 2 10 1 15 2 2 0 1 2 0.28 0.03 234 G 1 -2 -1 -1 -2 -1 -1 5 -1 -2 -2 -1 -2 -2 -1 0 -1 -2 0 -2 18 1 1 1 0 1 1 59 1 1 2 1 1 1 1 2 1 0 4 1 0.52 0.05 235 L 1 -2 -2 -2 -1 -2 -2 -2 -1 0 2 -2 0 3 -2 -1 -1 0 2 0 22 1 1 1 0 1 1 1 0 1 32 1 0 20 1 1 1 0 11 1 0.16 0.03 236 I -1 -2 -3 -3 -1 -2 -3 -3 -3 4 2 -2 3 0 -3 -2 -1 -2 -1 2 1 1 0 1 0 0 1 1 0 46 21 1 11 0 1 1 1 0 0 14 0.32 0.05 237 E -1 0 -1 0 -3 3 3 -2 -1 -2 0 2 -1 -2 -1 0 1 -2 -2 -2 1 1 0 1 0 27 26 1 0 1 13 16 0 0 1 1 10 0 0 1 0.29 0.05 238 L -2 -2 -3 -3 -2 -2 -3 -3 -3 2 4 -3 2 0 -3 -2 -1 -2 -1 1 1 1 0 1 0 0 1 1 0 7 85 1 0 0 1 1 1 0 0 1 0.50 0.08 239 R -2 7 -1 -2 -4 0 -1 -3 -1 -4 -3 2 -2 -4 -3 -1 -2 -4 -2 -3 0 97 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 1.12 0.15 240 K -1 4 -1 -2 -3 0 0 -3 0 -3 -2 3 -2 -1 -2 -1 1 -1 3 -2 0 28 0 0 0 0 0 0 0 0 0 39 0 0 0 0 13 0 20 0 0.42 0.08 241 L -2 -3 -4 -4 -2 -3 -4 -4 -4 3 4 -3 1 0 -3 -3 -1 -2 -2 2 0 0 0 0 0 0 0 0 0 35 60 0 0 0 0 0 0 0 0 4 0.51 0.08 242 E -1 2 0 1 -4 3 5 -3 3 -4 -3 1 -2 -3 -2 -1 -1 -3 -2 -3 0 11 0 3 0 19 56 0 11 0 0 0 0 0 0 0 0 0 0 0 0.64 0.09 243 A 4 -2 -1 -2 -1 -1 -1 -1 -2 -2 -2 -1 -1 -3 -1 1 3 -3 -2 -1 61 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 39 0 0 0 0.47 0.10 244 A 3 -2 -2 -2 -1 -1 -2 -1 -2 1 1 -1 0 -1 -2 1 0 -2 0 0 52 0 0 0 0 0 0 0 0 9 20 0 0 0 0 14 0 0 4 0 0.23 0.06 245 E -1 3 3 0 -3 2 2 -2 0 -3 -3 2 -2 -3 -2 1 -1 -3 -2 -3 0 25 20 0 0 11 21 0 0 0 0 13 0 0 0 9 0 0 0 0 0.42 0.06 246 D 0 -1 1 4 -3 1 4 -2 -1 -3 -3 0 -3 -4 -2 0 -1 -4 -3 -3 11 0 5 37 0 0 42 0 0 0 0 3 0 0 0 2 0 0 0 0 0.59 0.08 247 I -2 -4 -4 -4 -2 -3 -4 -4 -4 5 1 -3 1 -1 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 80 0 0 0 0 0 0 0 0 0 20 0.62 0.11 248 A 4 -2 -1 -2 -1 -1 -1 0 -2 -2 -2 -1 -2 -3 -1 3 1 -3 -2 -1 71 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 4 0 0 0 0.50 0.10 249 Y 0 1 0 -1 -2 2 1 -2 1 -1 -2 1 -1 0 -2 1 0 -1 3 -1 3 4 4 0 0 14 8 0 4 6 0 12 0 0 0 19 4 0 21 0 0.19 0.04 250 Q 0 0 -1 -1 -2 3 2 -2 -1 1 -1 0 -1 -2 -2 1 3 -3 -2 0 4 4 0 0 0 21 16 0 0 15 0 0 0 0 0 4 35 0 0 0 0.24 0.05 251 L -2 -3 -4 -4 -2 -3 -3 -4 -3 3 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 23 67 0 5 0 0 0 0 0 0 5 0.46 0.05 252 S 3 -1 1 -1 -1 -1 -1 0 -1 -2 -2 -1 -2 -3 -1 4 1 -3 -2 -1 40 0 5 0 0 0 0 0 0 0 0 0 0 0 0 55 0 0 0 0 0.43 0.06 253 R -1 4 2 -1 -3 1 1 -1 -1 -3 -3 3 -2 -3 -2 0 0 -3 -2 -3 0 35 15 0 0 3 5 4 0 0 0 28 0 0 0 8 3 0 0 0 0.41 0.04 254 S 1 -1 1 -1 -1 -1 -1 1 -1 -3 -3 -1 -2 -3 -1 5 1 -3 -2 -2 0 0 5 0 0 0 0 6 0 0 0 0 0 0 0 89 0 0 0 0 0.57 0.07 255 R 1 2 0 -1 -2 1 0 0 -1 -3 -3 1 -2 -3 4 0 -1 -3 -2 -2 21 13 5 0 0 12 0 6 0 0 0 11 0 0 27 5 0 0 0 0 0.45 0.03 256 N -2 -1 6 1 -3 2 0 0 0 -4 -4 0 -2 -4 -2 0 -1 -4 -3 -3 0 0 84 0 0 11 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0.83 0.08 257 I -1 2 -2 -2 -2 0 -1 -3 -2 1 0 3 0 -2 -2 -1 -1 -3 -2 3 0 13 0 0 0 0 0 0 0 8 0 34 0 0 0 0 0 0 0 45 0.22 0.04 258 T 1 -2 -2 -3 -1 -2 -2 -2 -3 2 0 -2 0 -2 -2 0 3 -3 -2 3 14 0 0 0 0 0 0 0 0 4 6 0 0 0 0 0 31 0 0 45 0.25 0.04 259 Y -2 -2 -3 -4 -3 -2 -3 -4 1 -2 -1 -2 1 3 -4 -2 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 94 0 1.15 0.09 260 L -2 -3 -4 -4 -2 -3 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 6 87 0 0 0 0 0 0 0 0 7 0.53 0.05 261 P -1 -2 1 -1 -3 -1 -1 -2 -2 -3 -3 -1 -2 -3 7 -1 1 -3 -3 -2 1 0 13 0 0 0 0 1 0 0 1 0 0 0 70 1 11 0 0 0 1.33 0.05 262 A 2 -2 -1 -1 -1 -1 -1 2 -2 -2 -2 -1 -1 0 -1 2 2 -2 -1 -1 33 0 0 0 0 0 0 17 0 0 0 0 0 7 0 29 14 0 0 0 0.27 0.03 263 G 0 -2 2 2 -3 -1 -1 4 -1 -4 -4 -1 -3 -3 -2 1 -1 -3 -3 -3 0 0 14 16 0 0 0 54 0 0 0 0 0 0 0 16 0 0 0 0 0.59 0.03 264 Q -1 0 2 0 -3 4 2 2 0 -3 -3 0 -1 -3 -2 1 1 -3 -2 -2 0 0 13 0 0 41 9 21 0 0 0 0 0 0 0 7 10 0 0 0 0.36 0.02 265 S 0 -1 2 -1 -2 1 -1 -1 -1 -1 1 -1 0 -2 -2 2 1 -3 -2 -1 0 0 21 0 0 8 0 0 0 0 30 0 0 0 0 33 9 0 0 0 0.17 0.02 266 V -1 -2 -2 -3 -1 -2 -2 -3 -3 2 2 -2 3 -1 -3 -1 1 -2 -1 2 0 0 0 0 0 0 0 0 0 0 28 0 25 0 0 0 15 0 0 32 0.26 0.02 267 L -2 -3 -4 -4 -2 -2 -3 -4 -3 1 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.56 0.04 268 L -2 -2 -3 -4 -2 -2 -3 -4 -2 1 3 -3 3 4 -3 -3 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 53 0 13 34 0 0 0 0 0 0 0.40 0.02 269 Q 1 0 4 0 -2 2 0 -1 0 -3 -3 0 -2 -3 -2 1 0 -3 -2 -2 28 0 52 0 0 21 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.38 0.01 270 L -2 -2 -3 -4 -1 -2 -3 -4 -3 1 4 -2 3 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 84 0 16 0 0 0 0 0 0 0 0.44 0.01 271 P -1 -2 -2 -2 -3 -1 -1 -2 -2 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.04 0.00 272 Q -1 1 0 0 -3 6 2 -2 0 -3 -2 1 0 -3 -1 0 -1 -2 -2 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.64 0.00 K Lambda Standard Ungapped 0.1350 0.3194 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1350 0.3194 PSI Gapped 0.0410 0.2670