Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 M -1 -2 -2 -3 -2 0 -2 -3 -2 1 2 -2 6 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.34 0.00 2 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.00 3 Q -1 -1 -1 -1 -3 3 0 -2 -1 -3 -3 0 -2 -4 7 -1 -1 -3 -3 -3 0 0 0 0 0 35 0 0 0 0 0 0 0 0 65 0 0 0 0 0 1.21 0.00 4 S 1 -1 0 -1 -2 0 0 -1 -1 -3 -3 0 -2 -3 5 3 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 33 67 0 0 0 0 0.65 0.00 5 C 0 -4 -3 -4 10 -3 -4 -3 -3 -1 -1 -3 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.20 0.00 6 Y -2 -2 -2 -3 -3 -2 -2 -3 2 -1 -1 -2 -1 3 -3 -2 -2 2 7 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0.85 0.00 7 N -2 0 6 1 -3 0 0 0 1 -4 -4 0 -2 -3 -2 1 0 -4 -2 -3 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.72 0.00 8 F -2 -3 -3 -4 -3 -4 -4 -3 -1 0 0 -3 0 7 -4 -3 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.73 0.00 9 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.00 10 K -1 2 0 -1 -3 1 1 -2 -1 -3 -3 5 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.51 0.00 11 E -1 0 0 2 -4 2 6 -2 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.00 12 Q -1 1 0 0 -3 6 2 -2 0 -3 -2 1 0 -4 -1 0 -1 -2 -2 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.65 0.00 13 H -2 0 1 -1 -3 0 0 -2 8 -4 -3 -1 -2 -1 -2 -1 -2 -3 2 -4 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0.85 0.00 14 C 0 -4 -3 -4 10 -3 -4 -3 -3 -1 -1 -3 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.20 0.00 15 Q -1 1 0 0 -3 6 2 -2 0 -3 -2 1 0 -4 -1 0 -1 -2 -2 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.65 0.00 16 K -1 2 0 -1 -3 1 1 -2 -1 -3 -3 5 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.51 0.00 17 A 4 -2 -2 -2 0 -1 -1 0 -2 -1 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.40 0.00 18 S 1 -1 1 0 -1 0 0 0 -1 -3 -3 0 -2 -3 -1 4 2 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.45 0.00 19 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 2 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.47 0.00 20 Q -1 1 0 0 -3 6 2 -2 0 -3 -2 1 0 -4 -1 0 -1 -2 -2 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.65 0.00 21 K -1 4 0 -1 -4 1 1 -2 -1 -3 -3 4 -2 -3 -1 0 -1 -3 -2 -3 0 33 0 0 0 0 0 0 0 0 0 67 0 0 0 0 0 0 0 0 0.52 0.00 22 G 0 -2 0 0 -3 0 2 5 -1 -4 -4 -1 -3 -4 -2 0 -1 -3 -3 -3 0 0 0 0 0 0 33 67 0 0 0 0 0 0 0 0 0 0 0 0 0.65 0.00 23 A 4 -2 -2 -2 0 -1 -1 0 -2 -1 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.40 0.00 24 E -1 0 0 2 -4 2 6 -2 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.00 25 A 4 -2 -2 -2 0 -1 -1 0 -2 -1 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.40 0.00 26 A 4 -2 -2 -2 0 -1 -1 0 -2 -1 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.40 0.00 27 V 0 -3 -3 -4 -1 -2 -3 -4 -3 3 1 -3 1 -1 -3 -2 0 -3 -1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.34 0.00 28 K -1 2 0 -1 -3 1 1 -2 -1 -3 -3 5 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.51 0.00 29 P -1 -2 -2 -2 -3 -1 -1 -2 -2 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.04 0.00 30 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.00 31 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.00 32 V 3 -2 -2 -2 -1 -1 -1 -1 -2 1 -1 -1 0 -2 -1 0 0 -3 -2 2 65 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 35 0.23 0.00 33 P -1 -2 -3 -2 -2 -2 -2 -3 -3 -1 1 -2 0 -2 7 -1 -1 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 32 0 0 0 68 0 0 0 0 0 1.16 0.00 34 H -2 0 1 -1 -3 0 0 -2 8 -4 -3 -1 -2 -1 -2 -1 -2 -3 2 -4 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0.85 0.00 35 H -2 0 1 -1 -3 0 0 -2 8 -4 -3 -1 -2 -1 -2 -1 -2 -3 2 -4 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0.85 0.00 36 V 0 -3 -3 -4 -1 -2 -3 -4 -3 3 1 -3 1 -1 -3 -2 0 -3 -1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.34 0.00 37 V 0 -3 -3 -4 -1 -2 -3 -4 -3 3 1 -3 1 -1 -3 -2 0 -3 -1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.34 0.00 38 A 4 -2 -2 -2 0 -1 -1 0 -2 -1 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.40 0.00 39 T 0 -2 -2 -2 -1 -2 -2 -3 -3 2 0 -2 0 -1 -2 0 3 -3 -2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 35 0 0 65 0.24 0.00 40 V -1 -3 -3 -4 -1 -3 -3 -4 -4 4 1 -3 1 0 -3 -2 -1 -3 -1 3 0 0 0 0 0 0 0 0 0 65 0 0 0 0 0 0 0 0 0 35 0.35 0.00 41 Q -1 1 0 0 -3 6 2 -2 0 -3 -2 1 0 -4 -1 0 -1 -2 -2 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.65 0.00 42 E -1 0 0 2 -4 2 6 -2 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.00 43 I -1 -3 -4 -4 -1 -3 -4 -4 -4 4 2 -3 1 0 -3 -3 -1 -3 -1 3 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0.39 0.00 44 Q -1 1 0 0 -3 6 2 -2 0 -3 -2 1 0 -4 -1 0 -1 -2 -2 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.65 0.00 45 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.00 46 Q -1 -1 -2 -2 -2 3 0 -3 -1 1 3 -1 2 0 -2 -2 -1 -2 -1 0 0 0 0 0 0 35 0 0 0 0 65 0 0 0 0 0 0 0 0 0 0.24 0.00 47 A 4 -2 -2 -2 0 -1 -1 0 -2 -1 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.40 0.00 48 A 4 -2 -2 -2 0 -1 -1 0 -2 -1 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.40 0.00 49 V 0 -3 -3 -4 -1 -2 -3 -4 -3 3 1 -3 1 -1 -3 -2 0 -3 -1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.34 0.00 50 G 0 -3 0 -1 -3 -2 -2 6 -2 -4 -4 -2 -3 -3 -2 0 -2 -3 -3 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.04 0.00 51 E -1 0 0 2 -4 2 6 -2 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.00 52 L -2 -3 -4 -4 -1 -3 -3 -4 -3 4 3 -3 2 0 -3 -3 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 65 35 0 0 0 0 0 0 0 0 0 0.36 0.00 53 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.00 54 L -1 -1 -2 -2 -2 3 0 -3 -1 1 3 -1 2 0 -3 -2 -1 -2 -1 0 0 0 0 0 0 32 0 0 0 0 68 0 0 0 0 0 0 0 0 0 0.25 0.00 55 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.00 56 E -1 0 0 2 -4 2 6 -2 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.00 57 W -3 -3 -4 -5 -3 -2 -3 -3 -3 -3 -2 -3 -2 1 -4 -3 -3 12 2 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 2.30 0.00 58 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.00 59 A 4 -2 -2 -2 0 -1 -1 0 -2 -1 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.40 0.00 60 M -1 -1 -1 1 -3 1 4 -3 -1 -1 0 0 3 -2 -2 -1 -1 -3 -2 -1 0 0 0 0 0 0 65 0 0 0 0 0 35 0 0 0 0 0 0 0 0.34 0.00 61 A 3 -2 -2 -2 -1 -1 -1 -1 -2 1 -1 -1 0 -2 -1 1 0 -3 -2 2 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 33 0.24 0.00 62 V 0 -3 -3 -4 -1 -2 -3 -4 -3 3 1 -3 1 -1 -3 -2 0 -3 -1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.34 0.00 63 M -1 1 -1 -1 -3 1 0 -2 -1 -1 0 4 3 -2 -2 -1 -1 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 65 35 0 0 0 0 0 0 0 0.24 0.00 64 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.00 65 L -1 -2 -3 -2 -2 -2 -2 -3 -3 -1 1 -2 0 -2 7 -1 -1 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 35 0 0 0 65 0 0 0 0 0 1.08 0.00 66 L 0 -1 0 -1 -1 -1 -1 -1 -2 0 2 -1 0 -1 -2 3 1 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 35 0 0 0 0 65 0 0 0 0 0.19 0.00 67 L -2 5 -1 -2 -3 0 -1 -3 -1 -1 2 1 0 -1 -3 -1 -1 -3 -2 -1 0 65 0 0 0 0 0 0 0 0 35 0 0 0 0 0 0 0 0 0 0.36 0.00 68 C -1 -2 -3 -4 6 -2 -3 -3 1 -1 -1 -2 -1 2 -3 -2 -1 1 6 -1 0 0 0 0 35 0 0 0 0 0 0 0 0 0 0 0 0 0 65 0 0.66 0.00 69 C 0 -4 -3 -4 10 -3 -4 -3 -3 -1 -1 -3 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.20 0.00 70 C 0 -4 -3 -4 10 -3 -4 -3 -3 -1 -1 -3 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.20 0.00 71 L -2 -2 -3 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.00 72 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 1 5 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.00 73 D -2 -2 1 6 -4 0 2 -1 -1 -3 -4 -1 -3 -4 -2 0 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.00 K Lambda Standard Ungapped 0.1336 0.3265 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1336 0.3265 PSI Gapped 0.0410 0.2670