Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 M -2 -2 -3 -4 -2 -1 -3 -4 -2 0 1 -2 8 -1 -3 -2 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 1.14 0.22 2 K -1 3 -1 -1 -4 1 0 -2 -1 -3 -3 6 -2 -4 -2 -1 -1 -4 -2 -3 0 12 0 0 0 0 0 0 0 0 0 88 0 0 0 0 0 0 0 0 0.82 0.14 3 V 3 -2 -3 -3 -1 -2 -2 0 -3 1 -1 -2 0 -1 -2 0 -1 -3 -2 3 44 0 0 0 0 0 0 6 0 2 0 0 0 3 0 0 0 0 0 45 0.30 0.10 4 L -1 -3 -4 -4 -1 -3 -3 -4 -3 2 3 -3 1 -1 -3 -2 -1 1 -1 3 4 0 0 0 0 0 0 0 0 0 45 0 0 0 0 0 0 2 0 49 0.42 0.10 5 W -2 -3 -4 -4 0 -3 -3 -4 -3 0 0 -3 -1 1 -4 -3 -2 9 1 3 0 0 0 0 2 0 0 0 0 0 6 0 0 7 0 0 0 44 0 40 1.11 0.15 6 A 2 -2 -3 -3 -1 -2 -2 -2 -3 1 2 -2 0 1 -2 -1 0 -2 -1 1 37 0 0 0 0 0 0 0 0 0 37 0 0 7 0 0 2 0 0 17 0.23 0.07 7 A 4 -2 -2 -2 -1 -1 -2 -1 -2 -1 -1 -1 -1 -2 -2 0 3 -3 -2 1 58 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 26 0 0 15 0.38 0.10 8 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 4 -3 1 0 -3 -3 -1 -2 -2 2 0 0 0 0 0 0 0 0 0 0 78 0 0 1 0 0 0 0 0 21 0.57 0.11 9 L 4 -2 -3 -3 -1 -2 -2 -1 -3 0 0 -2 0 -2 -2 0 -1 -3 -2 3 57 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 33 0.34 0.10 10 V 0 -3 -3 -4 -1 -3 -3 -3 -4 2 1 -3 0 -1 -3 -2 -1 -3 -2 5 7 0 0 0 0 0 0 0 0 6 8 0 0 1 0 0 0 0 0 78 0.50 0.12 11 T 1 -2 -2 -2 -1 -2 -2 -2 -2 0 3 -2 1 -1 -2 0 3 -2 -2 0 13 0 0 0 0 0 0 1 0 0 43 0 0 0 0 1 35 0 0 4 0.25 0.07 12 F -2 -3 -3 -4 -2 -3 -3 -3 -2 1 3 -3 1 5 -3 -3 -2 0 1 0 1 0 0 0 0 0 0 1 0 4 38 0 0 52 0 1 0 0 0 0 0.57 0.10 13 L -2 -3 -4 -4 -2 -3 -4 -4 -3 1 5 -3 1 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.77 0.14 14 A 3 -2 -1 -2 -1 -1 -1 -1 -2 -2 -2 -1 -1 -3 -2 1 4 -3 -2 -1 47 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 53 0 0 0 0.53 0.13 15 G -1 -3 -1 -2 -3 -3 -3 6 -3 -5 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.42 0.17 16 C -1 -3 -2 -3 8 -2 -3 -1 -3 -2 -2 -2 -2 -3 -3 2 1 -3 -3 -2 0 0 0 0 60 0 0 3 0 0 0 0 0 0 0 29 8 0 0 0 1.04 0.18 17 Q -2 2 -1 -1 -4 6 1 -2 -1 -3 -1 0 -1 -3 -2 -1 -2 3 -2 -3 0 12 0 0 0 73 3 2 0 0 5 0 0 0 0 0 0 5 0 0 0.80 0.18 18 A 5 -2 -2 -3 -1 -2 -2 0 -2 -2 -2 -1 -2 -3 -2 0 0 -3 -3 -1 94 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 2 0 0 0 0.73 0.17 19 K -2 4 0 3 -4 1 1 -2 -1 -3 -3 1 -2 -3 -2 -1 -1 2 -2 -3 0 46 0 30 0 2 7 0 0 0 0 7 0 0 0 0 0 4 0 0 0.57 0.11 20 V 0 -1 -1 -1 -1 -1 -1 -1 -1 1 1 -1 1 0 -1 -1 0 -1 0 2 4 2 2 4 1 2 3 5 1 2 10 3 6 2 2 3 5 1 4 37 0.05 0.02 21 E -1 0 0 1 -1 1 3 -1 0 -1 -1 0 -1 1 0 0 0 -1 0 -1 4 3 2 4 1 7 37 4 1 3 5 3 1 11 3 4 3 1 2 3 0.17 0.02 22 Q 0 0 0 0 -1 2 1 0 0 -1 -1 0 0 -1 2 0 0 -1 -1 -1 5 3 3 3 1 24 8 7 1 3 8 4 1 2 11 4 4 1 2 4 0.13 0.01 23 A 0 0 0 1 -1 0 2 0 2 -1 -1 0 -1 -1 0 0 0 -1 0 0 12 3 2 9 1 3 18 6 10 3 5 3 1 2 4 4 3 1 2 8 0.08 0.01 24 V 0 -1 -1 -1 -1 -1 -1 -1 -1 1 0 -1 0 1 1 0 0 -1 0 1 5 3 3 3 1 3 4 5 1 3 10 4 1 11 8 4 4 1 2 24 0.03 0.01 25 E 0 0 0 0 -1 1 2 0 0 -1 -1 1 -1 -1 0 0 0 4 0 -1 5 3 3 4 1 4 23 7 1 3 6 10 1 2 3 4 4 9 2 4 0.14 0.01 26 T 0 0 0 1 -1 1 0 -1 -1 -1 -1 0 -1 -1 3 0 1 -1 -1 0 5 5 2 9 1 12 3 4 1 3 7 3 1 2 15 5 11 1 2 6 0.13 0.01 27 E 0 1 0 0 -1 1 2 0 0 -1 -1 1 -1 -1 0 0 0 -1 -1 -1 11 8 2 3 1 5 26 6 1 3 5 9 1 2 3 4 3 1 2 3 0.12 0.01 28 P -1 -1 -1 1 -1 0 0 0 -1 0 0 -1 -1 -1 4 -1 0 -2 -1 0 3 2 2 11 1 4 3 6 1 2 12 2 1 2 29 3 4 1 1 11 0.31 0.03 29 E -1 0 0 1 -2 2 4 -1 0 -2 -2 1 -1 -2 0 0 -1 -2 -1 -2 4 2 2 5 1 10 42 4 1 2 3 8 1 1 4 3 2 1 1 2 0.29 0.04 30 P 0 -1 -1 -1 -2 0 -1 -1 -1 -1 0 -1 -1 -2 6 -1 -1 -2 -2 -1 9 2 2 2 1 4 2 3 1 2 10 2 1 1 46 3 2 0 1 5 0.67 0.05 31 E -1 0 0 1 -2 1 4 -1 5 -2 -1 0 -1 -2 -1 -1 -1 -2 0 -2 2 2 1 4 1 2 41 3 24 2 5 2 1 1 2 2 2 0 1 2 0.36 0.06 32 L 0 -1 -2 -2 -1 -1 -1 -2 -1 1 1 -1 0 3 0 -1 0 -1 1 1 6 2 2 2 1 2 2 3 1 2 10 2 2 28 6 3 3 0 1 24 0.12 0.03 33 R -1 1 -1 -1 -2 1 0 -1 1 -2 -1 0 -1 -1 -1 -1 0 7 0 -2 3 10 2 2 1 10 6 4 6 2 5 4 1 1 3 2 8 27 1 2 0.44 0.05 34 Q 0 0 0 1 -2 4 2 -1 0 -2 -1 0 -1 -2 0 0 -1 -2 -1 -1 5 3 2 7 1 37 19 3 1 2 6 2 1 1 4 2 2 0 1 2 0.29 0.05 35 Q -1 1 -1 -1 -2 5 1 -1 0 -2 -2 0 -1 -2 2 0 -1 1 -1 -2 2 5 1 1 0 50 8 4 1 1 2 1 1 1 12 2 2 2 1 2 0.43 0.08 36 T 2 -1 0 3 -2 0 0 -1 -1 -2 -1 -1 -1 -2 1 1 1 -2 -2 -1 26 1 2 28 0 2 1 1 0 1 8 1 0 1 7 9 11 0 1 1 0.22 0.05 37 E -1 1 0 1 -2 0 3 0 -1 -1 -1 0 -1 0 -1 1 0 -2 -1 0 2 7 1 9 0 1 33 8 0 1 3 4 1 6 2 11 2 0 0 9 0.16 0.04 38 W -2 -2 -3 -3 -3 -2 -2 -1 -3 -3 -2 -2 -2 -1 4 -2 -2 10 0 -3 1 2 1 1 0 1 1 6 0 1 1 1 0 0 27 1 1 55 0 1 1.62 0.17 39 Q -1 0 0 1 -3 6 1 -2 0 -3 -3 1 -1 -3 -2 -1 -1 -2 -2 -3 1 1 1 9 0 75 1 1 0 1 1 6 0 0 1 1 1 0 0 1 0.77 0.16 40 S 1 1 0 0 -1 0 -1 0 2 -2 -2 0 -2 -2 -1 3 1 -3 -1 -2 16 9 1 4 0 1 1 5 9 1 1 1 0 0 1 45 3 0 0 1 0.27 0.07 41 G 0 -1 0 1 -2 -1 -1 3 -2 -2 -2 -1 -2 -2 3 1 0 -3 -2 -1 1 1 4 10 0 1 1 27 0 1 1 3 0 1 18 19 1 0 1 10 0.32 0.05 42 Q -1 0 0 0 -2 4 2 -1 0 -2 -2 1 -1 -2 1 0 -1 -1 -1 -2 3 2 2 5 1 46 8 3 1 2 3 11 1 1 5 3 2 0 1 2 0.34 0.06 43 R -1 1 -1 1 -2 0 0 -2 -1 -2 -2 1 -2 -3 6 -1 -1 -3 -2 -2 2 9 1 10 0 5 1 2 1 1 2 7 1 1 52 2 1 0 1 1 0.88 0.08 44 W -3 -3 -4 -4 -3 -3 -3 -3 -3 -3 -2 -3 -2 2 -4 -3 -3 11 1 -3 1 0 0 0 0 0 1 1 0 0 1 0 0 9 0 1 0 83 0 1 2.53 0.25 45 E 0 -1 0 4 -4 2 5 -2 -1 -4 -3 0 -3 -4 -2 -1 -1 -4 -3 -3 9 0 0 27 0 8 56 0 0 0 0 0 0 0 0 0 0 0 0 0 0.72 0.13 46 L -1 3 -1 -1 -2 2 1 -3 -1 -1 1 1 0 -2 -2 -1 1 -3 -2 -1 4 24 0 0 0 17 12 0 0 0 26 3 0 0 0 0 14 0 0 0 0.22 0.07 47 A 3 -2 -2 -3 -1 -2 -2 -2 -3 1 0 -2 2 -2 1 0 0 -3 -2 2 45 0 0 0 0 0 0 0 0 3 0 0 14 0 8 0 6 0 0 24 0.29 0.10 48 L -1 -1 -2 -3 -2 -1 -1 -3 -2 1 3 2 1 -1 -2 -2 -1 -2 -2 2 1 0 0 0 0 0 0 1 0 0 46 27 0 0 0 1 0 0 0 21 0.24 0.09 49 G 0 -2 1 4 -3 -1 1 4 -2 -3 -3 -1 -3 -3 -2 0 -1 -3 -3 -3 4 0 3 38 0 0 9 39 0 0 1 0 0 0 0 3 0 0 0 0 0.58 0.10 50 R -2 5 -2 -2 -3 0 -1 -3 -1 -1 0 0 -1 2 1 -2 -2 -2 -1 -1 1 51 0 0 0 0 0 1 0 0 12 0 0 16 9 1 0 0 0 6 0.39 0.10 51 F 1 -2 -3 -3 -2 -2 -2 -2 -2 1 0 -2 2 5 -3 -1 -1 -1 2 0 22 0 0 0 0 0 0 0 0 7 6 0 12 39 0 0 3 0 7 0 0.35 0.11 52 W -1 1 -3 -3 -3 -2 -3 -3 -3 -3 -3 -2 -2 -1 -3 -2 2 10 0 -3 7 11 0 0 0 0 0 0 0 0 1 0 0 0 0 0 22 56 0 0 1.54 0.25 53 D -2 -2 0 5 -3 1 2 -2 -2 -1 -2 -1 -2 -3 -2 -1 -1 -4 -3 1 0 0 2 54 0 7 13 0 0 0 1 0 0 0 0 0 0 0 0 20 0.61 0.15 54 Y -3 -3 -3 -4 -4 -3 -1 -5 0 -3 -3 -3 -3 1 -4 -3 -3 1 8 -3 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 94 0 1.80 0.36 55 L -2 -3 -4 -4 -2 -3 -4 -4 -3 1 3 -3 1 3 -4 -3 -2 -2 0 3 0 0 0 0 0 0 0 0 0 0 47 0 0 21 0 0 0 0 0 32 0.54 0.16 56 R -1 4 2 3 -3 0 1 -2 -1 -3 -3 0 -3 -4 -2 2 0 -4 -3 -3 0 34 9 26 0 0 6 0 0 0 0 0 0 0 0 18 7 0 0 0 0.51 0.15 57 W 1 0 -2 -2 -3 3 0 -2 -2 -2 -2 -1 -2 -2 -3 -1 1 8 -1 0 15 4 0 0 0 26 4 0 0 0 0 0 0 0 0 2 11 29 0 9 0.70 0.19 58 V -1 -3 -4 -4 -2 -3 -4 -4 -4 2 3 -3 0 -1 -3 -3 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 10 29 0 0 0 0 0 0 0 0 61 0.63 0.18 59 Q -1 0 2 -1 -3 4 0 -1 -1 -4 -3 3 -2 -4 -2 2 -1 -3 -3 -3 0 0 10 0 0 32 0 4 0 0 0 33 0 0 0 21 0 0 0 0 0.54 0.18 60 T 0 -2 3 3 -2 -1 0 -2 -2 -2 -2 -1 -2 -3 -2 1 3 -4 -3 -2 6 0 17 27 0 0 4 0 0 0 4 0 0 0 0 6 36 0 0 0 0.46 0.15 61 L 0 -1 3 -1 -2 1 -1 0 2 -1 2 -1 -1 -2 -2 2 -1 -3 -2 -2 4 0 21 0 0 9 0 6 6 0 29 0 0 0 0 25 0 0 0 0 0.21 0.12 62 S 3 -2 -1 -2 -2 -2 -2 3 -2 -3 -3 -1 -2 -3 -2 3 1 -3 -3 -2 32 0 0 0 0 0 0 31 0 0 0 0 0 0 0 29 8 0 0 0 0.53 0.15 63 E -2 3 0 4 -4 0 2 -2 -1 -4 -4 3 -3 -4 -2 -1 -2 -4 -3 -3 0 18 2 29 0 0 18 0 0 0 0 33 0 0 0 2 0 0 0 0 0.60 0.16 64 Q -2 -1 0 4 -4 4 3 -1 -1 -4 -4 1 -2 -4 -2 -1 -2 -4 -3 -3 0 0 0 32 0 33 21 4 0 0 0 10 0 0 0 0 0 0 0 0 0.69 0.18 65 V 2 -3 -3 -3 -2 -2 -3 -2 -1 1 0 -2 1 0 -3 -1 -1 -1 4 2 32 0 0 0 0 0 0 0 0 4 6 0 4 0 0 0 0 0 26 29 0.36 0.15 66 Q -1 0 -2 -3 -2 3 -1 -3 -2 1 0 -1 0 -2 -3 -2 0 -3 -2 4 0 6 0 0 0 27 0 0 0 6 7 2 0 0 0 0 4 0 0 49 0.37 0.16 67 E 1 -1 1 1 -3 1 4 -2 -1 -3 -3 0 -2 -4 -2 1 0 -4 -3 -3 16 0 6 5 0 5 53 0 0 0 0 2 0 0 0 11 2 0 0 0 0.56 0.16 68 E -2 -1 2 0 -4 5 3 -2 4 -4 -4 0 -2 -4 -2 -1 -2 -3 -2 -4 0 0 9 1 0 49 26 1 14 0 0 0 0 0 0 0 0 0 0 0 0.81 0.22 69 L -2 -3 -4 -4 -2 -3 -4 -4 -3 2 4 -4 1 4 -4 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 10 56 0 1 31 0 0 0 0 0 2 0.65 0.17 70 L -2 -1 -1 2 -3 3 3 -3 -1 -2 1 0 -1 -2 -2 -1 1 -3 -2 -2 0 0 0 10 0 24 28 0 0 0 24 4 0 0 0 0 10 0 0 0 0.35 0.13 71 S 2 -1 1 -1 -2 0 -1 1 -2 -3 -3 2 -2 -3 -2 3 1 -3 -3 -2 16 0 6 0 0 3 0 10 0 0 0 17 0 0 0 41 7 0 0 0 0.36 0.13 72 S 0 -2 0 -1 -2 -1 -1 -2 2 -3 -3 -1 -2 -3 -1 5 3 -4 -2 -2 0 0 2 0 0 0 0 0 6 0 0 0 0 0 1 71 20 0 0 0 0.72 0.23 73 Q 2 1 -1 2 -3 4 2 -2 0 -3 -3 0 -2 -4 -2 0 0 -3 -2 -2 26 6 0 12 0 32 14 0 1 0 0 2 0 0 0 0 6 0 0 0 0.41 0.14 74 V -1 -3 -4 -4 -2 -3 -3 -4 -3 1 3 -3 3 0 -3 -3 -1 -2 1 3 1 0 0 0 0 0 0 0 0 0 44 0 10 0 0 0 0 0 6 39 0.50 0.15 75 T -1 -2 -1 -2 -2 0 0 4 -2 -1 -3 -1 -2 -3 -2 0 4 -3 -3 -2 0 0 0 0 0 6 6 36 0 3 0 0 0 0 0 4 45 0 0 0 0.54 0.17 76 Q -2 1 -1 -1 -4 6 1 -3 -1 -4 -3 4 -2 -4 -2 0 -1 -3 -3 -3 0 4 0 0 0 54 2 0 0 0 0 33 0 0 0 6 2 0 0 0 0.81 0.22 77 E 0 0 -1 0 -4 5 4 -2 1 -3 -3 0 -2 -4 -2 -1 -2 -3 -2 -3 6 0 0 0 0 51 36 0 2 0 1 0 0 0 0 0 0 0 0 0 0.81 0.21 78 L -2 -3 -4 -5 -2 -3 -4 -5 -3 1 5 -3 2 0 -4 -3 -2 -2 1 0 0 0 0 0 0 0 0 0 0 0 88 0 6 0 0 0 0 0 6 0 0.84 0.22 79 R -2 1 5 2 -3 -1 -1 -2 -1 -3 -3 1 -2 -4 -2 0 3 -4 -3 -3 0 7 44 13 0 0 0 0 0 0 0 7 0 0 0 4 26 0 0 0 0.58 0.17 80 A 1 -2 -2 -3 -2 0 -2 -3 -3 0 3 -2 2 -1 -2 -1 1 -3 -2 1 18 0 0 0 0 6 1 0 0 0 43 0 5 0 0 0 15 0 0 11 0.25 0.11 81 L -2 -1 2 -2 -3 1 -1 -3 -1 0 3 2 0 -1 -3 -2 -2 -3 -2 -1 0 0 14 0 0 6 0 0 2 0 56 23 0 0 0 0 0 0 0 0 0.34 0.15 82 M -2 -3 -4 -4 -2 -3 -3 -4 -3 2 3 -3 4 3 -4 -3 -2 -2 0 1 0 0 0 0 0 0 0 0 0 11 38 0 25 20 0 0 0 0 0 6 0.54 0.15 83 D 0 -1 -1 2 -3 3 2 -2 -1 -1 1 0 -1 -2 -2 0 0 -3 -2 -1 6 0 0 13 0 20 21 0 0 0 23 4 0 0 0 6 6 0 0 2 0.24 0.10 84 E -3 -2 0 6 -5 -1 4 -3 -2 -4 -5 -1 -4 -5 -2 -1 -2 -5 -4 -4 0 0 0 70 0 0 30 0 0 0 0 0 0 0 0 0 0 0 0 0 1.23 0.25 85 T -1 -1 4 -1 -3 -1 -1 -2 -1 -2 -1 2 -2 -3 -2 1 3 -4 -3 -2 0 0 33 0 0 0 0 0 0 0 6 20 0 0 0 7 30 0 0 0 0.41 0.16 86 M -2 -3 -4 -4 -3 -2 -3 -4 1 1 3 -3 5 -1 -4 -3 -2 8 -1 0 0 0 0 0 0 0 0 0 6 6 29 0 32 0 0 0 0 25 0 4 0.85 0.21 87 K 0 -1 0 4 -3 -1 0 2 -2 -3 -3 2 -3 -4 -2 0 1 -4 -3 -3 7 0 0 33 0 0 0 20 0 0 0 24 0 0 0 6 9 0 0 0 0.43 0.13 88 E -1 -1 0 1 -3 2 4 -2 -1 -3 -3 1 -2 -4 -2 2 2 -3 -3 -2 1 0 3 4 0 8 39 0 0 0 0 6 0 0 0 19 20 0 0 0 0.47 0.14 89 L -1 -3 -4 -4 -2 -3 -3 -4 -4 2 4 -3 1 0 -3 -3 -1 -3 -2 3 4 0 0 0 0 0 0 0 0 4 55 0 0 2 0 0 0 0 0 36 0.54 0.16 90 K -1 0 2 -1 -3 1 0 1 1 -3 -3 3 -2 -3 -2 2 1 -4 -2 -3 0 0 15 0 0 6 0 9 4 0 0 27 0 0 0 29 9 0 0 0 0.36 0.13 91 A 3 -2 0 -1 -2 -1 0 -1 -2 -2 -2 -1 -2 -3 1 2 3 -3 -3 -1 35 0 2 1 0 0 6 1 0 0 0 0 0 0 6 24 26 0 0 0 0.40 0.14 92 Y 0 -3 -2 -3 -1 -2 -3 -3 0 -2 -2 -2 -2 2 -3 -1 2 0 7 -2 10 0 0 0 1 0 0 0 0 0 0 0 0 6 0 3 20 0 60 0 0.88 0.23 93 K 2 1 -2 -2 -2 0 -1 -2 -2 -1 -1 2 -1 2 -2 0 1 -2 -1 1 29 9 0 0 0 1 0 0 0 0 0 21 0 13 0 4 8 0 0 14 0.18 0.10 94 S 1 -1 0 3 -2 1 2 1 -1 -3 -3 1 -2 -3 -2 2 0 -3 -3 -2 18 0 1 22 0 6 11 9 0 0 0 7 0 0 0 23 2 0 0 0 0.33 0.10 95 E -2 1 2 2 -4 1 3 -1 -1 -4 -3 3 -2 -4 -2 -1 0 -4 -3 -3 0 6 12 12 0 1 33 4 0 0 0 26 0 0 0 0 6 0 0 0 0.47 0.13 96 L -2 -3 -4 -4 -2 -3 -4 -4 -4 1 5 -3 1 -1 -4 -3 0 -3 -2 1 0 0 0 0 0 0 0 0 0 0 85 0 0 0 0 0 6 0 0 9 0.74 0.20 97 E -2 4 -1 0 -4 4 3 -3 1 -4 -3 1 -2 -4 -2 0 -1 -3 -2 -3 0 28 0 1 0 25 31 0 4 0 0 6 0 0 0 6 0 0 0 0 0.63 0.16 98 E 0 0 1 0 -4 2 5 -1 -1 -4 -3 2 -2 -4 -2 -1 0 -4 -3 -3 7 0 6 0 0 11 52 2 0 0 0 17 0 0 0 0 4 0 0 0 0.59 0.16 99 Q 0 1 -1 1 -4 5 2 -3 -1 -4 -3 3 -2 -4 -2 -1 -2 -3 -3 -3 6 4 0 6 0 51 8 0 0 0 0 26 0 0 0 0 0 0 0 0 0.71 0.20 100 L -2 -3 -4 -4 -2 -3 -4 -4 -4 2 4 -3 3 -1 -4 -3 -2 -3 -2 1 0 0 0 0 0 0 0 0 0 15 73 0 10 0 0 0 0 0 0 2 0.72 0.18 101 T 0 -3 -1 0 -2 -2 -2 4 -3 -1 -2 -2 -2 -3 -2 0 1 -3 -3 1 7 0 0 6 0 0 0 48 0 0 0 0 0 0 0 5 13 0 0 22 0.46 0.13 102 P -2 -3 -3 -3 -4 0 -2 -3 1 -4 -4 -2 -4 -5 8 -1 -2 -5 -4 -4 0 0 0 0 0 6 0 0 4 0 0 0 0 0 87 3 0 0 0 0 2.11 0.30 103 V -2 -3 0 -3 -2 -1 -3 -4 -2 1 0 -3 3 3 -3 -2 -1 -1 3 3 0 0 6 0 0 4 0 0 0 2 0 0 13 20 0 0 1 0 15 38 0.38 0.15 104 A 4 -2 -2 -2 -1 -2 -2 -1 -2 -1 -2 -1 -1 -2 -2 1 3 -3 1 1 54 0 0 0 0 0 0 0 0 0 0 1 0 0 0 4 26 0 6 10 0.43 0.17 105 E -1 0 -1 -1 -3 4 3 -3 0 -2 -2 1 0 -3 -2 0 1 -3 -2 0 0 3 0 0 0 32 28 0 2 0 0 4 3 0 0 7 11 0 0 10 0.42 0.14 106 E -2 -1 -1 2 -4 2 6 -3 -1 -3 -4 0 -3 -4 -2 -1 0 -4 -3 -2 0 0 0 11 0 6 73 0 0 0 0 0 0 0 0 0 6 0 0 4 0.90 0.22 107 T -1 -3 -2 -3 -2 -2 -3 -3 -1 1 2 -2 1 4 -3 -1 2 -2 0 1 4 0 0 0 0 0 0 0 1 6 26 0 4 27 0 0 26 0 0 6 0.32 0.12 108 R -1 3 -1 -2 -3 2 -1 -3 4 -4 -3 2 -2 -2 -3 1 -2 8 0 -3 4 19 0 0 0 10 0 0 14 0 0 14 0 0 0 12 0 27 0 0 0.74 0.18 109 A 2 -2 -1 3 -2 0 3 2 -2 -3 -3 -1 -2 -3 -2 0 0 -4 -3 -2 31 0 0 20 0 2 23 16 0 0 0 0 0 0 0 2 6 0 0 0 0.39 0.12 110 R -2 5 3 -1 -4 2 -1 -3 4 -3 -3 1 1 -3 -3 -1 0 -3 -2 -3 0 45 18 0 0 10 0 0 12 0 0 3 6 0 0 2 4 0 0 0 0.58 0.17 111 L -2 -3 -4 -5 -2 -3 -4 -4 -4 1 5 -3 1 1 -4 -3 -2 3 -1 1 0 0 0 0 0 0 0 0 0 0 82 0 0 4 0 0 0 6 0 8 0.76 0.20 112 S 1 0 -1 -1 -2 0 3 -2 1 -2 -1 -1 1 -3 -2 2 2 -3 -2 -2 13 6 0 0 0 0 27 0 4 0 6 0 6 0 0 24 15 0 0 0 0.26 0.11 113 K -2 1 -1 -2 -4 1 1 -3 -2 -4 -4 6 -2 -4 1 -1 -1 -4 -3 -3 0 0 0 0 0 4 6 0 0 0 0 81 0 0 6 0 4 0 0 0 0.89 0.24 114 E -2 -2 1 4 -4 0 5 -3 -1 -4 -4 -1 -3 -3 -2 -1 -2 -3 1 -4 0 0 6 35 0 0 53 0 0 0 0 0 0 0 0 0 0 0 6 0 0.87 0.21 115 L -1 -2 -2 -3 -2 -2 -2 -3 -3 0 2 -2 0 -2 -2 1 4 -3 -2 1 0 0 0 0 0 0 0 0 0 0 34 0 0 0 0 8 51 0 0 7 0.47 0.18 116 Q -1 -1 -1 2 -4 4 4 -3 -1 -3 -3 1 -2 -4 -2 -1 0 -3 -3 -2 4 0 0 11 0 31 41 0 0 0 0 6 0 0 0 0 4 0 0 3 0.64 0.17 117 A 2 0 -2 -2 -2 1 1 -1 -2 -1 -1 1 -1 -2 -2 0 -1 5 -1 0 34 6 0 0 0 6 12 2 0 0 4 8 0 0 0 5 0 13 0 10 0.27 0.11 118 A 2 -3 -4 -4 -2 -3 -3 -3 -3 0 4 -3 1 -1 -3 -2 -2 -3 -2 1 28 0 0 0 0 0 0 0 0 0 66 0 0 0 0 0 0 0 0 6 0.50 0.17 119 Q -1 5 -1 -2 -4 4 0 -1 -1 -4 -3 3 -2 -4 -3 -1 -2 -3 -3 -3 4 47 0 0 0 26 0 5 0 0 0 18 0 0 0 0 0 0 0 0 0.73 0.19 120 A 3 -1 -1 -1 -2 3 3 0 -1 -2 -3 0 -2 -3 -2 0 -1 -3 -3 -1 37 0 2 0 0 19 30 4 0 0 0 0 0 0 0 2 0 0 0 6 0.41 0.15 121 R -2 4 -1 0 -4 1 4 -3 -1 -4 -3 2 -3 -4 -2 -1 -2 -4 -3 -3 0 39 0 0 0 0 48 0 0 0 0 13 0 0 0 0 0 0 0 0 0.81 0.20 122 L -2 -3 -4 -4 -2 -2 -3 -4 -3 3 3 -3 5 -1 -4 -3 -2 -3 -2 1 0 0 0 0 0 0 0 0 0 24 42 0 27 0 0 0 0 0 0 7 0.60 0.17 123 G -1 2 3 1 -3 1 0 2 -1 -3 -2 0 0 -3 -2 0 0 -3 -3 -2 2 15 22 6 0 7 2 23 0 0 3 4 6 0 0 5 6 0 0 0 0.27 0.09 124 A 1 1 -1 -1 -3 1 0 -1 -2 -2 -3 4 -2 -3 0 1 1 -3 -2 -1 19 2 0 3 0 6 0 1 0 0 0 46 0 0 3 7 10 0 0 4 0.35 0.13 125 D -3 -2 2 6 -5 -1 2 -2 0 -4 -5 -1 -4 -4 -3 -1 -2 -5 -4 -4 0 0 9 74 0 0 15 0 3 0 0 0 0 0 0 0 0 0 0 0 1.16 0.23 126 M -1 -3 -4 -4 -2 -2 -3 -4 -3 1 4 -3 6 -1 -4 -3 -2 -3 -2 2 3 0 0 0 0 0 0 0 0 0 45 0 38 0 0 0 0 0 0 15 0.66 0.20 127 E -1 -1 -1 1 -4 1 6 -3 1 -4 -4 0 -3 -4 -2 -1 0 -4 -3 -3 3 0 0 3 0 1 83 0 3 0 0 0 0 0 0 0 4 0 0 0 1.00 0.23 128 D -2 -1 0 5 -4 0 5 -2 -1 -4 -4 0 -3 -4 -2 -1 -2 -4 -3 -3 0 0 2 39 0 0 50 0 0 0 0 5 0 0 0 0 0 0 0 0 0.87 0.19 129 V 0 -3 -3 -4 -2 -2 -3 -3 -3 1 3 -3 1 -1 -3 -2 -1 -3 -2 4 8 0 0 0 0 0 0 0 0 0 34 0 2 0 0 0 0 0 0 52 0.44 0.14 130 C -2 5 -1 -2 0 1 0 -2 -1 -3 -2 4 -2 -3 -2 -1 -1 -3 -2 -3 1 52 0 1 2 3 1 1 0 1 2 31 0 0 1 3 1 0 0 1 0.69 0.16 131 G 1 1 2 1 -2 2 1 -1 -1 -2 -2 1 -2 -3 -1 1 1 -3 -2 -2 12 9 18 4 0 10 10 3 0 1 1 9 0 0 1 11 7 0 0 2 0.22 0.06 132 R -2 5 0 -2 -3 1 0 -2 -1 -3 -3 4 -2 -3 -2 0 -1 -3 -2 -3 1 50 3 1 0 2 1 1 0 1 1 31 0 0 1 7 1 0 0 1 0.68 0.16 133 L -1 -2 -3 -3 -2 -2 -3 -3 -3 2 3 -2 3 -1 -3 -1 -1 -2 -2 2 1 1 0 1 0 0 1 1 0 7 53 1 9 0 1 4 1 0 0 20 0.39 0.11 134 V 1 0 -1 -1 -2 3 1 1 -1 -1 0 0 1 -2 -2 0 0 -2 -2 0 20 3 0 1 0 21 10 10 0 1 10 1 7 0 1 5 6 0 0 5 0.14 0.07 135 Q -2 -1 -2 -1 -3 4 0 -3 0 -3 -2 -1 -2 -4 6 -1 -2 -3 -3 -3 1 1 0 3 0 36 1 1 2 1 3 1 0 0 49 1 1 0 0 1 1.09 0.20 136 Y -2 -2 -1 -3 -3 -2 -2 -3 5 -2 -2 -2 -2 2 -3 -2 -2 0 7 -2 1 1 3 1 0 0 1 1 23 1 1 1 0 3 1 1 1 0 63 1 1.12 0.23 137 R 2 4 -2 -2 -2 -1 -1 -2 -2 -1 2 1 1 -2 -2 -1 -1 -3 -2 -1 24 37 0 0 0 0 0 0 0 0 25 5 5 0 0 1 0 0 0 0 0.30 0.12 138 G 0 -1 2 2 -3 2 1 1 1 -3 -3 0 -2 -3 -2 1 0 -3 -2 -2 6 0 17 17 0 14 6 12 3 0 0 5 0 0 0 14 3 0 0 0 0.30 0.08 139 E -2 -1 -1 2 -4 2 5 -3 -1 -4 -3 2 -3 -4 -2 -1 -2 -4 -3 -3 0 0 0 10 0 6 69 0 0 0 0 11 0 0 0 0 0 0 0 0 0.85 0.20 140 V 0 -3 -3 -4 -2 -3 -3 -3 -3 1 2 -3 1 3 -3 -2 -1 -2 0 3 7 0 0 0 0 0 0 0 0 0 22 0 3 19 0 0 0 0 0 45 0.37 0.13 141 Q -1 1 -1 -1 -3 6 0 -2 1 -3 -3 1 -2 -3 -2 1 0 -2 1 -3 0 7 1 0 0 57 0 0 3 0 0 8 0 0 0 11 4 0 6 0 0.62 0.19 142 A 2 -1 0 0 -2 3 1 -1 -1 -2 -2 1 -1 -3 1 1 2 -3 -2 -1 22 0 4 2 0 21 10 0 0 0 0 7 0 0 5 6 20 0 0 1 0.27 0.10 143 M 0 1 -2 -2 -2 0 -1 -2 -2 -1 0 3 5 0 -2 -1 0 -2 -2 0 7 6 0 0 0 3 0 0 0 0 4 29 34 5 0 0 6 0 0 4 0.29 0.14 144 L -1 -3 -3 -4 -2 -2 -3 -3 -3 1 3 -3 2 1 -3 -2 -1 7 0 0 4 0 0 0 0 0 0 0 0 6 46 0 7 7 0 0 4 19 0 4 0.55 0.13 145 G -1 -1 2 0 -3 2 0 4 2 -4 -3 0 -2 -3 -2 -1 -1 -3 -2 -3 0 0 11 5 0 13 6 49 6 0 0 4 0 0 0 0 2 0 0 0 0.55 0.13 146 Q -1 0 -1 1 -3 4 3 -2 2 -3 -3 1 -2 -3 1 0 -1 -3 -2 -3 0 0 0 7 0 38 24 0 8 0 0 6 0 0 6 5 3 0 0 0 0.53 0.14 147 S -1 -1 3 0 -3 1 2 -2 3 -3 -3 0 -2 0 -2 2 0 -2 1 -2 0 0 21 0 0 6 20 0 9 0 0 4 0 5 0 23 4 0 6 0 0.30 0.10 148 T 1 -2 -2 -2 -1 0 -2 -2 -2 1 1 -2 1 -1 -1 0 2 -3 -2 2 16 0 0 0 0 5 0 1 0 6 13 0 4 0 1 4 23 0 0 24 0.17 0.08 149 E -2 0 -1 3 -5 2 5 -3 -1 -4 -4 0 -3 -4 -2 -1 -2 -4 -3 -4 0 5 0 19 0 6 69 0 0 0 0 0 0 0 0 0 0 0 0 0 0.96 0.22 150 E -1 1 -1 2 -4 1 4 0 1 -3 -1 1 -2 -3 -2 -1 -1 -3 -2 -3 2 5 0 8 0 2 53 6 4 0 10 7 0 0 0 0 2 0 0 0 0.46 0.14 151 L -2 -3 -4 -4 -2 -2 -3 -4 -2 1 3 -3 3 0 -4 -3 -2 -1 4 1 0 0 0 0 0 0 0 0 0 1 50 0 14 0 0 0 0 0 25 10 0.57 0.17 152 R 0 6 -1 -2 -4 3 0 -3 -1 -4 -3 2 -2 -4 -3 -1 -2 -4 -3 -3 7 62 0 0 0 17 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0.88 0.21 153 V 1 -1 1 0 -2 2 2 0 -1 -2 -1 0 -1 0 -1 1 1 -2 -1 -1 22 2 7 1 0 16 15 4 0 0 7 0 0 6 2 7 9 0 0 1 0.15 0.07 154 R -1 5 -1 -1 -4 3 1 -2 1 -3 -3 3 -2 -3 -2 -1 -2 -3 -2 -3 2 42 0 0 0 18 5 0 3 0 0 27 0 0 0 0 0 0 0 0 0.65 0.16 155 L -2 -3 -3 -4 -2 -3 -3 -4 -3 1 4 -3 2 1 -3 -3 -1 -2 -1 3 0 0 0 0 0 0 0 0 0 0 51 0 8 4 0 0 0 0 0 33 0.48 0.14 156 A 2 0 1 -1 -2 1 1 2 -1 -2 -2 1 -2 -3 -1 1 1 -3 -2 -2 23 3 7 0 0 6 14 15 0 0 0 11 0 0 0 6 13 0 0 0 0.22 0.07 157 S 0 0 -1 -2 -2 -1 -1 -2 -2 -3 -3 0 -2 -3 5 2 2 -3 -3 -2 5 5 0 0 0 0 0 0 0 0 0 6 0 0 41 22 17 0 0 0 0.78 0.15 158 H -2 -2 1 -2 -3 -1 -1 -3 6 -1 0 -2 -1 1 -3 -2 -2 -1 5 0 0 0 6 0 0 0 2 0 38 0 10 0 0 2 0 0 0 0 28 10 0.63 0.17 159 L 2 -1 -2 -3 -2 -2 -2 0 -2 0 2 -2 1 1 -2 -1 0 -2 -1 0 24 5 0 0 0 0 0 8 0 4 39 0 2 6 0 2 7 0 0 0 0.16 0.08 160 R 0 4 -1 1 -3 2 2 -1 1 -3 -3 1 -2 -3 -2 -1 0 -3 -2 -2 7 35 0 8 0 13 17 2 4 0 0 4 0 0 0 0 6 0 0 0 0.40 0.11 161 K -1 2 0 0 -4 1 4 -2 1 -3 -3 4 -2 -3 -2 -1 -1 -3 -2 -3 0 9 2 3 0 4 35 2 3 0 0 38 0 0 0 0 0 0 0 0 0.55 0.14 162 L -1 -3 -3 -4 -2 -2 -3 -4 -2 1 4 -3 3 2 -3 -3 -2 -2 1 1 2 0 0 0 0 0 0 0 0 0 61 0 12 7 0 0 0 0 6 8 0.47 0.14 163 R -2 5 -1 -2 -4 2 1 -3 -1 -3 -3 2 -2 -3 -2 0 -1 -3 -2 -3 0 58 0 0 0 12 7 0 0 0 0 10 0 0 1 7 0 0 0 0 0.72 0.17 164 K 1 1 0 1 -3 0 1 -2 -1 -3 -3 3 -2 -3 1 0 1 -3 -2 -2 15 3 3 8 0 0 10 0 0 0 0 40 0 0 5 0 13 0 0 0 0.32 0.11 165 R -1 4 -1 -2 -3 2 -1 0 1 -2 0 2 -1 -3 -2 -1 0 -3 -2 -2 0 44 0 0 0 11 0 10 3 0 11 10 0 0 0 0 7 0 0 1 0.39 0.12 166 L 0 -2 0 -3 -2 -2 -2 -3 -3 2 3 -2 1 -1 -3 -1 -1 3 -1 1 10 0 6 0 0 0 0 0 0 13 46 0 3 0 0 6 0 6 0 8 0.25 0.09 167 L -1 3 1 -1 -2 1 -1 -2 -1 -1 1 1 1 -2 -2 0 0 -2 -1 -1 4 26 10 2 0 8 0 0 0 0 25 4 3 0 0 8 6 0 1 2 0.17 0.08 168 R 0 3 -1 -1 -3 3 2 -1 -1 -3 -2 1 -2 -3 -2 0 0 -3 -2 -2 9 27 0 0 0 22 16 4 0 0 0 8 0 0 0 3 7 0 0 2 0.36 0.10 169 D -2 -1 3 4 -3 2 1 -2 2 -3 -3 1 -2 -3 -2 -1 -1 -3 -2 -3 1 0 23 37 0 11 3 1 8 0 1 10 0 0 1 1 1 0 0 1 0.55 0.13 170 A 3 -2 -2 -2 -1 -2 -2 -1 -2 0 1 -2 0 -2 -2 0 1 -3 -2 2 42 0 0 1 0 0 1 1 0 1 12 1 0 0 1 1 13 0 0 25 0.26 0.11 171 D -2 -1 -1 3 -4 3 5 -1 -1 -3 -3 0 -2 -3 -2 -1 -1 -3 -3 -3 1 0 0 19 0 15 55 3 0 0 1 1 0 0 1 1 1 0 0 1 0.72 0.16 172 D -1 0 2 4 -3 2 3 -2 -1 -3 -2 0 -2 -3 -2 -1 -1 -3 -2 -2 3 3 13 29 0 12 31 1 0 0 4 1 0 0 1 1 1 0 0 2 0.49 0.12 173 L -2 -3 -3 -4 -2 -2 -3 -4 -3 1 4 -3 2 0 -3 -3 -2 -2 1 0 1 0 0 1 0 0 1 1 0 4 76 1 3 0 1 1 1 0 7 2 0.57 0.15 174 Q -2 4 -1 -2 -3 5 0 -2 2 -3 -3 1 -2 -3 -2 -1 -2 -3 -2 -3 1 37 0 1 0 44 1 1 6 0 1 6 0 0 1 1 1 0 0 1 0.72 0.18 175 K 1 2 0 -1 -3 3 1 -2 -1 -3 -3 3 -2 -3 -2 0 0 -3 -2 -2 14 15 4 0 0 17 9 0 0 0 0 33 0 0 0 3 4 0 0 0 0.39 0.11 176 R -1 4 1 -1 -3 2 0 -2 -1 -3 -3 3 -2 -3 -2 1 0 -3 -2 -3 0 34 6 0 0 14 0 0 0 0 0 26 0 0 0 12 4 0 0 0 0.51 0.14 177 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 4 -3 3 0 -3 -3 -2 -2 -2 1 0 0 0 0 0 0 0 0 0 0 72 0 9 3 0 0 0 0 0 12 0.60 0.16 178 A 3 -2 -1 -1 -2 -1 1 0 -2 -2 -2 -1 0 -3 -2 0 2 -3 -2 0 49 0 0 1 0 0 14 3 0 0 1 2 4 0 0 3 19 0 0 4 0.32 0.13 179 V 0 -3 -3 -3 -3 -2 -2 -3 -3 -1 -1 -2 -2 -3 6 -2 0 -4 -3 2 4 0 0 0 0 0 0 0 0 0 3 0 0 0 57 0 4 0 0 26 1.11 0.19 180 Y -2 -3 -3 -4 -3 -2 -3 -4 0 -1 2 -3 -1 1 -3 -3 -2 0 7 0 1 0 0 0 0 0 0 0 0 0 27 0 0 0 0 0 0 0 60 8 0.85 0.21 181 Q 1 1 -1 -1 -2 1 -1 2 -1 -1 -1 1 1 -2 -2 1 -1 -2 -2 -1 18 8 1 1 0 8 1 22 0 4 1 10 10 0 1 13 1 0 0 3 0.17 0.06 182 A 2 -1 0 3 -2 0 2 -1 -1 -2 -2 0 -2 -3 -1 1 0 -3 -2 -2 32 1 1 21 0 4 16 1 0 1 1 5 0 0 1 9 6 0 0 1 0.29 0.09 183 G -1 0 0 3 -3 1 3 3 -1 -3 -3 0 -2 -3 -2 -1 -1 -3 -3 -3 1 6 4 18 0 3 35 27 0 1 1 1 0 0 1 1 1 0 0 1 0.46 0.11 184 A 1 -2 -3 -3 -1 -2 -2 -2 -2 1 3 -2 3 1 -2 -1 -1 -2 -1 1 22 0 0 0 0 0 1 1 0 9 35 0 12 5 0 1 2 0 0 10 0.23 0.09 185 R -2 5 -1 -2 -3 2 0 -2 0 -3 -2 2 -2 -3 -2 0 0 -1 -2 -2 1 55 0 0 0 13 2 1 2 0 2 11 0 0 0 4 4 1 0 1 0.62 0.16 186 E 1 -1 0 3 -3 2 4 -2 -1 -3 -3 1 -2 -3 -1 0 0 -3 -2 -2 14 0 0 18 0 10 38 1 0 0 1 7 0 0 0 5 4 0 0 1 0.44 0.11 187 G 0 2 0 -1 -2 -1 -1 4 -2 -3 -3 2 -2 -3 -2 0 -1 -3 -2 -2 8 13 3 1 0 1 1 44 0 1 1 17 0 0 1 3 4 0 0 3 0.42 0.10 188 A 4 -2 -2 -3 -1 -2 -2 -1 -2 1 1 -2 1 1 -2 0 -1 -2 -1 0 55 0 0 0 0 0 0 1 0 11 15 0 4 9 0 2 0 0 0 0 0.30 0.13 189 E -1 3 0 1 -3 2 3 -2 3 -3 -3 0 -2 -3 -2 1 -1 -3 -2 -3 3 22 4 8 0 7 33 1 10 0 1 0 0 0 0 10 0 0 0 0 0.42 0.11 190 R -1 4 -1 0 -3 4 0 -2 -1 -3 -2 1 -1 -3 -2 0 0 -3 -2 -1 1 36 0 4 0 34 0 1 0 0 2 6 0 0 0 6 5 0 0 4 0.51 0.15 191 G -1 0 3 -1 -3 1 -1 1 4 -3 -3 2 0 -3 -2 2 -1 -3 -2 -3 0 3 25 0 0 4 0 13 14 0 0 15 5 0 0 19 0 0 0 0 0.34 0.12 192 L -1 -3 -3 -3 -2 -2 -1 -4 -3 2 3 -3 1 -1 -3 -2 -1 -3 -2 3 4 0 0 0 0 0 5 0 0 8 33 0 3 0 0 0 0 0 0 44 0.38 0.13 193 S 0 0 0 2 -3 2 3 -1 -1 -3 -3 0 -2 -3 -2 2 0 -3 -2 -3 6 3 2 16 0 10 29 2 0 0 0 4 0 0 0 25 3 0 0 0 0.40 0.11 194 A 3 -1 0 0 -2 0 4 -2 -1 -2 -3 -1 -2 -3 -2 0 0 -3 -2 -1 35 0 3 0 0 2 44 0 0 0 0 0 0 0 0 3 7 0 0 5 0.44 0.15 195 I -2 -3 -4 -4 -2 -3 -3 -4 -3 3 4 -3 1 -1 -3 -3 0 -3 -2 2 0 0 0 0 0 0 0 0 0 28 54 0 0 0 0 0 5 0 0 10 0.51 0.14 196 R -2 5 -1 -2 -4 3 0 -3 1 -4 -3 3 -2 -4 -2 0 -2 -3 -2 -3 0 49 0 0 0 16 0 0 4 0 0 23 0 0 0 6 0 0 0 0 0.72 0.18 197 E 0 -1 0 1 -3 1 4 1 -1 -3 -3 0 -2 -4 -2 1 0 -3 -3 -3 5 0 3 4 0 2 52 11 0 0 0 0 0 0 0 16 5 0 0 0 0.51 0.15 198 R -2 4 1 0 -4 1 0 -2 4 -4 -3 3 -2 -3 -2 0 -1 -3 -2 -3 0 38 7 4 0 6 0 0 16 0 0 24 0 0 0 5 0 0 0 0 0.57 0.15 199 L -1 -3 -3 -4 -2 -3 -3 -1 -3 1 4 -3 2 1 -3 -3 -2 -2 -1 1 3 0 0 0 0 0 0 6 0 2 70 0 4 6 0 0 0 0 0 6 0.48 0.15 200 G 1 -1 -1 1 -2 0 0 3 -2 0 -2 -1 -1 -2 -2 1 1 2 -2 0 13 2 0 9 0 4 5 25 0 6 0 0 0 0 0 11 11 3 0 9 0.18 0.06 201 P -2 -3 -3 -2 -4 0 -2 -3 -3 -4 -4 -2 -3 -5 8 1 -2 -5 -4 -3 0 0 0 0 0 6 0 0 0 0 0 0 0 0 81 12 0 0 0 0 1.89 0.29 202 L -2 -1 -3 -3 -2 1 -2 -3 -1 0 3 -2 2 1 -3 -2 -1 -1 4 -1 0 2 0 0 0 12 0 0 0 0 46 0 5 3 0 0 3 0 25 0 0.40 0.14 203 V 2 0 -2 -2 -1 0 -1 0 -2 0 0 -1 2 -2 -2 1 0 -2 -2 2 25 5 1 1 0 4 1 5 0 1 8 1 8 0 1 11 1 0 0 29 0.13 0.08 204 E -1 -1 0 3 -3 0 4 -2 -1 -2 -3 0 -1 -3 -2 1 -1 -3 -2 -2 4 1 4 17 0 0 53 1 0 3 1 1 2 0 1 8 2 0 0 1 0.53 0.14 205 Q 0 0 -1 0 -3 4 4 -2 -1 -3 -3 1 -2 -3 -2 0 -1 -3 -2 -2 6 2 1 1 0 36 39 1 0 1 1 6 0 0 1 4 1 0 0 1 0.60 0.15 206 G 0 -2 -2 -1 -2 -2 -2 2 -1 0 1 -2 1 1 -2 -1 -1 -1 2 0 8 1 1 3 0 1 1 23 0 1 25 1 7 8 1 4 1 0 9 6 0.13 0.06 207 R -2 5 -1 -2 -3 3 0 -2 1 -3 -3 2 -2 -3 -1 -1 -1 -3 -2 -3 1 54 1 1 0 17 1 1 3 1 1 13 0 1 2 1 1 0 0 1 0.67 0.16 208 V 0 0 -1 1 -2 1 1 -2 -1 0 0 0 0 -2 0 0 1 -2 -2 0 12 7 1 12 0 8 13 1 0 1 14 1 0 1 4 3 11 0 0 12 0.09 0.04 209 R -1 5 1 -1 -3 1 0 0 1 -3 -2 3 -2 -3 -2 -1 -1 -3 -2 -2 1 45 7 1 0 5 1 6 4 1 2 22 0 1 1 1 1 0 1 1 0.48 0.12 210 A 2 -2 -1 -2 -1 -1 -2 -1 -1 1 1 -1 0 0 -1 0 0 -2 -1 1 38 1 2 1 0 1 1 1 2 10 15 1 0 4 1 2 5 0 1 14 0.14 0.07 211 A 2 0 1 2 -1 -1 0 0 0 -1 -2 -1 -1 -2 -1 0 0 -2 -2 0 36 5 8 13 0 1 5 7 2 2 1 1 2 1 1 4 5 0 1 5 0.15 0.06 212 T 0 -1 1 0 -2 2 2 -1 0 -1 -2 0 -1 -2 2 0 3 -2 -1 -1 3 1 10 1 0 11 14 2 2 1 2 3 1 1 9 2 30 0 1 4 0.23 0.07 213 V -1 -1 1 -1 -1 0 -1 -1 -1 1 1 -1 1 0 -1 -1 0 -1 1 2 3 2 10 2 1 8 2 3 1 2 21 2 4 1 2 3 3 0 7 24 0.06 0.04 214 G 0 0 0 1 -1 0 0 2 0 -1 0 0 -1 -1 -1 0 0 -2 -1 0 4 3 4 9 1 2 8 21 2 2 9 9 1 1 2 7 4 0 1 10 0.07 0.02 215 S 2 -1 0 0 -1 0 2 0 -1 -2 -2 0 -1 -2 -1 2 1 -2 -1 -1 22 2 2 2 1 3 18 6 1 2 3 2 1 1 2 21 9 0 1 2 0.18 0.05 216 L -1 0 0 0 -1 -1 -1 -1 -1 0 2 0 0 -1 -1 -1 1 -2 -1 0 2 5 7 6 1 2 2 5 1 1 40 8 1 1 1 2 11 0 1 3 0.08 0.05 217 A 1 1 -1 -2 -1 -1 -1 -1 -1 0 0 0 0 0 0 0 0 -2 -1 0 25 10 1 1 0 1 2 3 1 9 13 7 1 7 4 2 8 0 1 6 0.05 0.03 218 G 1 1 1 1 -2 -1 -1 2 -1 -2 -2 0 -2 -2 -1 1 0 -2 -2 -2 12 12 7 10 0 1 1 23 0 1 2 1 0 1 1 17 7 0 1 2 0.21 0.05 219 Q -1 1 0 -1 -3 5 2 -2 0 -3 -2 2 -1 -3 -1 -1 -1 -2 -2 -2 1 7 3 1 0 50 12 1 1 1 2 14 0 1 1 1 1 0 1 1 0.57 0.15 220 P 0 -1 1 1 -2 0 0 0 -1 -2 -2 0 -2 -2 5 0 0 -2 -2 -2 10 1 8 8 0 3 6 5 1 1 2 8 1 1 33 7 3 0 1 2 0.47 0.07 221 L -2 -2 -3 -3 -2 -2 -2 -3 -2 1 4 -2 2 0 -2 -2 -1 -2 0 1 1 1 1 1 0 1 1 1 0 1 69 1 7 1 1 1 1 0 3 6 0.45 0.13 222 Q 0 3 -1 -1 -2 2 0 -2 0 -1 0 1 0 -2 -1 0 1 -2 -1 -1 8 22 1 1 0 18 3 2 1 1 10 9 3 1 1 4 11 0 1 1 0.18 0.06 223 E -1 -1 -1 2 -3 3 4 -1 -1 -3 -3 0 -2 -3 4 -1 -1 -3 -2 -2 1 1 1 11 0 17 37 3 0 1 2 1 0 1 20 1 1 0 1 1 0.55 0.12 224 R -1 5 -1 -2 -3 1 0 -2 2 -2 -1 2 -1 -2 -2 -1 -1 -2 1 -1 5 45 0 1 0 6 3 1 6 1 7 10 0 0 1 3 1 0 7 4 0.39 0.12 225 A 3 -2 -3 -3 -1 -2 -2 -2 -3 0 2 -2 0 -1 -2 0 -1 -3 -2 2 43 0 0 0 0 0 1 1 0 0 32 0 0 0 0 2 0 0 0 16 0.29 0.13 226 Q 0 1 1 0 -2 4 2 0 -1 -2 -1 0 -1 -3 -2 0 1 -2 -2 -2 7 7 8 3 0 35 15 5 0 1 5 1 0 1 1 1 8 0 0 1 0.31 0.11 227 A 3 -1 -1 1 -2 0 1 -1 0 -2 -2 -1 -2 -3 2 0 -1 -3 -2 -1 43 4 1 12 0 2 10 1 3 1 1 1 0 1 12 1 1 0 0 5 0.29 0.10 228 W -2 -2 -2 -3 -2 0 -2 -3 2 0 1 -2 0 2 -3 -2 -2 7 3 0 1 1 1 1 0 8 1 1 7 5 19 1 0 7 1 1 1 25 14 6 0.55 0.12 229 G 1 1 -1 -1 -2 1 -1 3 1 -2 -1 1 0 -2 -1 0 -1 -2 -2 -1 13 6 1 1 0 6 1 30 4 1 5 15 4 1 1 9 1 0 0 3 0.20 0.06 230 E 0 -1 -1 3 -3 3 4 -2 -1 -3 -3 0 -2 -4 -2 0 -1 -3 -3 -3 10 0 0 16 0 16 49 0 0 0 1 2 0 0 0 3 0 0 0 0 0.62 0.16 231 R -1 4 -1 0 -4 2 2 0 -1 -3 -2 3 -2 -3 -2 -1 -1 -3 -2 -3 2 31 0 6 0 11 15 7 0 0 4 21 0 0 0 0 3 0 0 0 0.42 0.12 232 L -1 -3 -4 -4 -2 -3 -4 -2 -3 2 4 -3 2 1 -4 -3 -2 -2 -2 0 2 0 0 0 0 0 0 3 0 9 73 0 6 3 0 0 0 0 0 2 0.61 0.18 233 R -1 5 0 0 -3 0 0 -2 0 -3 -3 2 0 -3 -2 0 1 -3 -2 -3 5 51 5 3 0 2 3 2 2 0 0 9 3 0 0 2 14 0 0 0 0.52 0.16 234 A 1 0 -1 -1 -2 1 1 3 1 -2 -3 -1 -2 -1 1 0 0 -3 -2 -1 17 3 0 0 0 11 13 25 5 0 0 0 0 3 6 7 6 0 0 3 0.24 0.08 235 R -2 4 0 -2 -3 3 0 -3 3 -3 -2 2 0 -2 -2 0 -1 -3 1 -3 0 37 3 0 0 17 0 0 10 0 3 13 3 0 0 5 2 0 6 0 0.46 0.15 236 M 0 -3 -4 -4 -2 -2 -3 -4 -3 2 4 -2 3 -1 -3 -2 -2 -3 -2 0 10 0 0 0 0 0 0 0 0 10 64 3 10 0 0 0 0 0 0 2 0.51 0.16 237 E 0 -1 -1 2 -4 2 5 0 -1 -3 -3 0 -3 -4 -2 -1 -1 -3 -3 -3 9 0 0 11 0 7 59 6 0 0 0 3 0 0 0 0 2 0 0 0 0.65 0.18 238 E 0 -1 1 2 -3 1 4 0 -1 -3 -3 1 -2 -4 2 0 -1 -3 -3 -3 7 0 6 9 0 6 43 5 0 0 0 8 0 0 9 5 0 0 0 0 0.46 0.12 239 M -1 -2 -1 -3 -2 -2 -2 -2 -2 1 3 -2 3 0 -3 -2 -1 -2 2 2 2 0 5 0 0 0 1 4 0 0 36 1 11 0 0 1 2 0 10 26 0.24 0.10 240 G 1 1 -1 -1 -2 -1 -1 4 1 -2 -2 1 -2 -3 -2 0 0 -3 -2 -1 14 9 1 1 0 1 1 38 4 1 1 12 0 0 1 6 4 0 0 7 0.30 0.08 241 S 1 -1 1 -1 -2 1 1 1 -1 -1 -2 -1 -1 0 0 1 1 -2 -1 -1 12 1 8 1 0 7 12 10 0 1 1 1 0 7 3 17 11 0 1 6 0.12 0.05 242 R -1 3 -1 1 -3 3 1 0 -1 -1 -2 2 1 -2 -1 0 -1 -2 -1 -2 1 23 1 7 0 20 7 7 0 5 1 11 5 1 2 4 1 0 3 1 0.23 0.07 243 T 2 -2 -2 -2 -1 -1 -2 -1 -2 0 1 -1 2 0 -2 0 1 -2 -1 0 34 1 1 1 0 1 1 3 0 4 21 1 11 3 1 1 9 0 1 6 0.15 0.08 244 R 1 4 -1 -1 -2 2 1 0 -1 -1 -2 1 -1 -2 -2 0 0 -2 -2 -1 15 34 1 1 0 9 6 5 0 7 1 8 0 1 1 5 4 0 0 1 0.26 0.09 245 D 0 0 0 4 -3 0 2 -1 -1 -3 -3 0 -2 -3 1 1 -1 -3 -2 -2 9 7 1 40 0 1 12 2 0 1 1 6 0 1 8 10 1 0 0 1 0.42 0.10 246 R -1 4 1 -2 -3 0 -1 -2 4 -2 -1 1 -2 -1 -2 0 0 -2 2 -2 3 40 9 0 0 0 1 1 14 0 5 4 0 2 0 7 5 0 8 1 0.36 0.12 247 L 1 -2 -3 -3 -2 -1 -3 -3 0 0 4 -2 1 0 -3 -2 -2 -2 -1 0 14 0 0 0 0 2 1 1 3 0 72 0 0 3 0 1 0 0 0 1 0.46 0.16 248 D 1 -1 1 4 -3 0 3 0 -1 -3 -3 -1 -3 -3 -2 1 -1 -4 -3 -3 13 0 5 29 0 2 34 4 0 0 0 0 0 0 0 10 2 0 0 0 0.49 0.13 249 E 1 -1 -1 2 -4 1 4 -2 1 -3 -3 1 -3 -4 2 -1 -2 -4 -3 -2 14 0 0 10 0 4 50 0 4 0 0 8 0 0 9 0 0 0 0 1 0.57 0.16 250 V -1 -3 -3 -4 -2 -1 -3 -4 -2 1 3 -3 2 0 -3 -2 -1 -2 2 3 3 0 0 0 0 4 0 0 0 5 40 0 7 0 0 0 0 0 13 28 0.38 0.13 251 K 0 5 0 -2 -3 1 0 -2 0 -3 -3 3 0 -3 -2 0 -1 -3 -2 -3 9 43 2 0 0 6 4 0 2 0 0 25 4 0 0 5 0 0 0 0 0.54 0.16 252 E 0 -1 -1 2 -4 3 5 -2 0 -3 -3 1 -2 -3 -2 -1 -1 -3 -2 -1 6 0 0 9 0 14 54 0 2 0 0 7 0 0 0 0 0 0 0 4 0.60 0.17 253 Q -1 1 -1 1 -3 5 1 0 0 -3 -3 2 -2 -3 -2 1 0 -3 -2 -3 2 4 0 7 0 47 1 7 1 0 0 12 0 0 0 11 5 0 0 0 0.48 0.16 254 V 0 -2 -3 -3 -1 -2 -2 -3 -3 1 3 -2 3 -1 -2 -2 -1 -2 -1 3 9 1 1 1 0 1 1 1 0 2 35 1 17 1 1 1 1 0 0 28 0.30 0.11 255 A 2 -1 1 0 -2 2 3 0 -1 -2 -2 0 -2 -3 -1 1 0 -3 -2 -2 31 1 6 2 0 12 26 7 0 1 1 1 0 1 1 6 3 0 0 1 0.29 0.10 256 E 0 -1 -1 2 -3 1 5 -1 -1 -3 -3 1 -2 -3 -1 0 -1 -3 -2 -2 9 1 1 8 0 1 55 3 0 1 1 9 0 1 1 7 1 0 0 1 0.50 0.13 257 V 0 -3 -3 -3 -2 -2 -3 -3 0 2 2 -2 2 1 -3 -2 -1 -1 2 3 5 0 0 0 0 0 0 0 3 6 22 0 5 6 0 0 0 0 12 38 0.29 0.10 258 R -1 4 1 -1 -3 2 0 -2 0 -3 -2 2 -2 0 -2 0 0 -3 -1 -2 0 38 10 0 0 12 0 0 1 0 3 16 0 6 0 9 3 0 0 0 0.40 0.12 259 A 3 -2 -1 -2 -2 -1 0 0 2 -2 -2 -1 -1 0 0 1 0 -3 -1 0 38 0 0 0 0 0 8 7 10 0 1 0 0 6 5 13 5 0 0 7 0.21 0.10 260 K 0 1 1 -1 -3 3 0 -2 -1 -3 -3 5 -2 -3 -2 0 0 -3 -2 -2 7 0 6 0 0 17 0 0 0 0 0 56 0 0 0 5 7 0 0 0 0.51 0.16 261 L 1 -3 -3 -4 -2 -2 -3 -3 -3 1 3 -3 4 -1 -3 -2 -1 -3 -2 2 17 0 0 0 0 0 0 0 0 1 40 0 18 0 0 0 0 0 0 23 0.39 0.14 262 E -2 1 -1 2 -4 2 5 -3 -1 -4 -4 1 -3 -4 -2 0 -1 -4 -3 -3 0 6 0 10 0 9 60 0 0 0 0 6 0 0 0 6 3 0 0 0 0.71 0.18 263 E -2 0 -1 2 -4 1 5 1 -1 -4 -4 1 -3 -4 -2 -1 -2 -4 -3 -4 0 4 0 12 0 0 68 10 0 0 0 6 0 0 0 0 0 0 0 0 0.80 0.20 264 Q 0 0 1 -1 -2 3 0 -2 3 -1 1 1 0 -2 -2 -1 0 -2 -1 -1 10 0 10 0 0 27 1 1 9 0 24 9 0 0 0 1 5 0 0 1 0.19 0.10 265 A 3 2 -2 -2 -2 -1 0 0 -2 -2 0 0 -1 -2 -2 0 0 -3 -2 -1 49 19 0 0 0 0 7 5 0 0 13 0 0 0 0 1 3 0 0 1 0.26 0.12 266 Q -1 1 1 0 -3 3 2 -2 -1 -2 -2 1 -1 1 -1 1 0 -2 -1 -2 1 5 5 3 0 22 17 1 0 0 1 9 0 10 2 17 6 0 0 1 0.25 0.09 267 Q 0 0 1 -1 -3 5 1 1 -1 -3 -3 2 -1 -3 -2 0 0 -3 -2 -2 9 0 5 0 0 45 7 12 0 0 1 12 0 0 0 1 5 0 0 1 0.44 0.14 268 I -2 -2 -3 -3 -2 -2 -3 -3 -2 2 3 -2 4 2 -3 -2 -1 -2 -1 1 1 1 1 1 0 1 1 1 0 13 39 1 24 11 1 1 1 0 0 4 0.37 0.11 269 R 0 4 -1 -2 -2 1 0 0 -1 -2 -1 2 0 -2 -2 0 -1 -2 -2 -1 6 37 1 1 0 7 1 7 0 1 7 14 3 0 1 7 1 0 0 7 0.26 0.08 270 L 0 -1 -1 -1 -2 1 1 -2 -1 -1 1 1 0 -2 4 -1 1 -2 -2 -1 4 1 1 1 0 5 10 1 0 1 22 17 0 1 22 1 11 0 1 1 0.27 0.07 271 Q -1 1 1 -1 -3 4 0 -2 2 -1 -2 2 -1 -3 -2 0 -1 -3 -1 1 1 3 6 0 0 36 0 1 9 0 1 20 0 0 0 6 0 0 0 16 0.33 0.12 272 A 4 -2 -2 -2 -1 -2 -2 -1 -2 0 1 -2 -1 -2 -2 0 1 -3 -2 0 64 0 0 0 0 0 0 1 0 3 15 0 0 0 0 1 7 0 0 6 0.36 0.13 273 E -1 0 -1 0 -4 2 5 -2 -1 -4 -3 2 -2 -4 -2 0 -1 -3 -3 -3 0 0 0 0 0 6 68 0 0 0 0 14 0 0 0 8 0 0 0 0 0.78 0.18 274 A 3 -2 -1 0 -2 -1 1 0 -2 -1 -2 -1 -2 -3 3 1 0 -3 -2 0 36 0 0 6 0 0 11 5 0 3 0 0 0 0 15 12 1 0 0 8 0.28 0.08 275 F 0 0 -3 -3 -2 -2 -2 -3 -2 1 2 -1 0 5 -3 -1 -2 -1 1 0 9 5 0 0 0 0 0 0 0 5 20 5 0 43 0 3 0 0 0 7 0.32 0.11 276 Q -1 2 -1 -2 -3 4 0 -2 0 0 0 2 0 -2 -2 -1 -1 -3 -2 0 4 9 0 0 0 43 0 1 1 5 14 14 0 0 0 1 0 0 0 6 0.33 0.12 277 A 3 -2 -1 1 -2 -1 2 1 -2 -2 -2 -1 -2 -3 -2 0 1 -3 -2 0 42 0 0 10 0 0 17 8 0 0 0 0 0 0 0 0 13 0 0 7 0.26 0.10 278 R -1 4 0 2 -3 2 1 -2 -1 -3 -3 2 -2 -3 -2 0 -1 -3 -2 -3 0 42 0 14 0 7 8 0 0 0 0 15 0 0 0 9 0 0 0 0 0.51 0.12 279 L -2 -3 -4 -4 -2 -3 -4 -4 -4 1 5 -3 2 0 -4 -3 -2 -2 -2 1 0 0 0 0 0 0 0 0 0 5 85 0 6 1 0 0 0 0 0 4 0.75 0.18 280 K -1 4 0 -1 -3 2 0 -2 -1 -3 -1 3 -1 -3 -2 1 0 -3 -2 -2 0 30 3 0 0 11 0 0 0 0 5 32 0 0 0 10 6 0 0 0 0.41 0.11 281 S 0 -1 0 1 -2 3 1 1 -1 -3 -3 0 -2 -3 -1 3 0 -3 -2 -2 6 0 0 7 0 21 5 12 0 0 1 5 0 0 0 36 4 0 0 0 0.32 0.10 282 W -1 -1 2 -2 -3 -2 -2 2 0 -3 -1 0 -2 -1 -3 -1 -2 9 0 -3 5 3 16 0 0 0 0 16 3 0 6 6 0 0 0 3 0 40 0 0 0.88 0.16 283 F -1 -2 -3 -3 -2 -2 -3 -3 -2 1 3 -3 1 4 -3 -2 -1 -1 1 0 6 0 0 1 0 0 1 1 0 5 44 1 0 35 0 1 4 0 0 1 0.41 0.11 284 E 1 -1 -1 1 -3 1 5 -2 -1 -2 0 0 -1 -3 -2 -1 -1 -3 -2 -1 13 0 0 7 0 1 58 0 0 0 16 0 0 0 0 0 0 0 0 3 0.47 0.14 285 P -2 -1 -3 -2 -4 -2 -1 -3 -3 -4 -4 -2 -3 -4 8 -2 -2 -4 -4 -3 0 4 0 0 0 0 4 0 0 0 0 0 0 0 90 0 0 0 0 0 2.11 0.26 286 L -2 -2 -3 -4 -2 -1 -3 -4 -2 1 3 -2 2 1 -3 -2 -1 -1 2 2 0 0 0 0 0 4 0 0 0 1 47 0 8 5 0 0 0 0 12 21 0.34 0.10 287 V 1 -2 -3 -3 -1 -2 -2 -3 -3 1 2 -2 2 -1 -3 0 0 -3 -2 3 14 0 0 0 0 0 0 0 0 0 18 0 10 0 0 6 5 0 0 47 0.29 0.11 288 E -2 -1 0 0 -5 3 6 -3 -1 -4 -4 0 -3 -4 -2 -1 -2 -4 -3 -3 0 0 3 0 0 11 85 0 0 0 0 1 0 0 0 0 0 0 0 0 1.07 0.23 289 D -2 -1 4 5 -4 -1 2 -2 -1 -4 -4 0 -3 -4 -2 0 -1 -5 -3 -4 0 0 27 56 0 0 9 0 0 0 0 6 0 0 0 3 0 0 0 0 0.85 0.17 290 M -2 -3 -3 -4 -2 -2 -3 -4 -3 2 2 -3 5 2 -3 -3 -1 -2 -1 3 0 0 0 0 0 0 0 0 0 12 15 0 34 13 0 0 0 0 0 26 0.46 0.14 291 Q -2 4 -1 -2 -4 4 0 -3 3 -4 -3 3 -2 -4 -2 -1 -2 -3 -2 -3 0 38 0 0 0 38 0 0 8 0 0 16 0 0 0 0 0 0 0 0 0.74 0.17 292 R -1 4 -1 -1 -3 0 0 1 -1 -3 -2 1 1 -3 -2 1 2 -3 -2 -2 0 39 0 0 0 3 6 12 0 0 0 5 6 0 0 10 19 0 0 0 0.35 0.10 293 Q -1 0 3 -1 -3 5 0 -2 1 -3 -3 2 -2 -4 -2 1 1 -3 -2 -3 0 0 17 0 0 46 0 0 3 0 0 12 0 0 0 15 7 0 0 0 0.53 0.15 294 W -2 -3 -4 -4 -3 -1 -3 -4 -3 1 2 -3 2 3 -4 -3 -2 9 1 0 0 0 0 0 0 3 0 0 0 7 29 0 6 13 0 0 0 37 0 5 0.94 0.16 295 A 3 1 -1 -1 -2 2 -1 0 -2 -2 -2 2 -1 -3 -2 0 -1 3 -2 -2 47 6 0 1 0 12 0 4 0 0 3 20 0 0 0 1 0 6 0 0 0.31 0.11 296 G -1 -2 2 1 -3 1 2 4 -1 -4 -4 -1 -3 -4 -2 1 -1 -3 -3 -3 0 0 12 6 0 7 19 46 0 0 0 0 0 0 0 8 0 0 0 1 0.53 0.10 297 L 0 -2 3 -2 -2 -2 -2 -3 -2 0 3 -2 2 -1 -3 -1 0 -3 -2 0 6 0 23 0 0 0 0 0 0 0 50 0 7 0 0 0 7 0 0 6 0.27 0.10 298 V 0 -2 -2 -3 -2 -2 -3 -3 -2 2 1 -2 2 1 -3 -1 2 -2 1 3 4 0 0 0 0 0 0 0 0 8 6 0 10 7 0 0 20 0 7 38 0.25 0.09 299 E -2 -1 -1 4 -4 1 5 -3 -1 -4 -4 0 -3 -4 -2 -1 -2 -4 -3 -3 0 0 0 26 0 2 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0.99 0.19 300 K -1 1 -1 0 -3 1 1 2 -1 -3 -3 4 -2 -4 -2 -1 0 -3 -3 -3 0 1 0 4 0 7 7 21 0 0 0 51 0 0 0 0 8 0 0 0 0.44 0.11 301 V 0 -3 -3 -4 -1 -3 -3 -4 -3 3 3 -3 1 -1 -3 -2 -1 -3 -2 3 7 0 0 0 0 0 0 0 0 27 34 0 2 0 0 0 0 0 0 30 0.39 0.09 302 Q 0 0 -1 -1 -3 6 1 -2 -1 -3 -3 1 -1 -4 -2 0 1 -3 -2 -2 8 0 0 0 0 71 0 0 0 0 0 7 0 0 0 0 14 0 0 0 0.76 0.19 303 A 1 1 -1 -1 -2 0 1 -2 -2 -1 0 4 -1 -3 -2 0 -1 -3 -2 0 20 0 0 0 0 0 8 0 0 0 10 50 0 0 0 3 0 0 0 9 0.27 0.09 304 A 3 -1 -1 -2 -1 -1 -1 -1 2 -2 -2 0 -2 -3 -1 3 0 -3 -2 -1 51 0 0 0 0 0 0 0 8 0 0 7 0 0 0 34 0 0 0 0 0.41 0.11 305 V -1 -2 -3 -3 -1 -2 -3 -3 -3 2 3 -2 2 0 -3 -2 -1 -2 -1 3 1 0 0 0 0 0 0 1 0 9 39 0 5 0 0 1 0 0 0 41 0.36 0.08 306 G 2 -1 -1 -1 -1 -1 -1 3 -1 -2 -2 -1 -2 -2 0 0 2 -2 -2 -1 29 3 0 1 0 0 1 35 2 1 1 1 0 0 3 1 20 0 0 1 0.33 0.05 307 T 2 -2 -1 -2 -1 -1 -1 -1 -2 -1 -1 -1 -1 -2 0 1 4 -3 -2 0 24 0 0 0 0 0 0 0 0 3 2 0 0 0 2 3 64 0 0 0 0.40 0.07 308 S 2 -1 1 -1 -1 0 -1 -1 -1 -1 -2 0 -1 -3 -1 3 1 -3 -2 -1 19 0 9 0 0 0 0 0 0 3 0 3 0 0 0 60 2 0 0 3 0.33 0.04 309 A 2 -1 -1 -1 -1 -1 -1 -1 -2 -2 -2 -1 -1 -2 5 1 1 -2 -2 -1 35 1 1 1 0 1 1 1 0 1 1 1 0 1 31 12 12 0 0 1 0.50 0.03 310 A 1 -2 0 -2 -1 -1 -1 -1 -2 0 1 -1 0 -2 -1 1 3 -3 -2 0 21 0 2 0 0 0 0 0 0 2 17 0 0 0 0 8 50 0 0 0 0.25 0.04 311 P 0 -2 -1 -1 -2 -1 -1 -2 -2 -2 -2 -1 -2 -3 6 2 1 -3 -2 -2 4 0 0 0 0 0 0 0 0 0 1 0 0 0 56 21 14 0 0 0 1.01 0.05 312 V 2 -1 -1 -2 -1 -1 -1 -2 -2 0 -1 0 0 -2 2 0 2 -3 -2 2 27 0 0 0 0 0 3 0 0 2 0 7 2 0 12 0 19 0 0 26 0.19 0.02 313 P 0 -2 -2 -2 -3 -1 -1 -2 -2 -3 -3 -1 -3 -4 7 0 -1 -4 -3 -3 3 0 0 0 0 0 0 0 0 0 0 0 0 0 88 9 0 0 0 0 1.83 0.06 314 S 1 -1 0 -1 -1 0 0 -1 -1 -1 -1 -1 -1 -2 0 4 1 -3 -2 0 0 0 0 0 0 6 0 0 0 4 3 0 0 0 3 74 3 0 0 8 0.32 0.04 315 D -1 0 0 3 -4 1 5 -2 0 -3 -3 1 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 21 0 0 70 0 0 0 0 4 0 0 0 4 0 0 0 0 0.65 0.03 316 N -1 0 5 1 -3 0 0 -1 0 -3 -3 2 -2 -3 -2 1 0 -4 -2 -3 0 0 67 5 0 0 0 0 0 0 0 19 0 0 0 4 5 0 0 0 0.53 0.03 317 H -1 0 0 -1 -3 4 1 -2 7 -3 -3 0 -1 -2 -2 -1 -1 -2 1 -3 0 0 0 0 0 40 0 0 60 0 0 0 0 0 0 0 0 0 0 0 0.69 0.03 K Lambda Standard Ungapped 0.1282 0.3154 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1282 0.3154 PSI Gapped 0.0410 0.2670