PSIBLAST 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Stephen F.
Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005)
"Protein database searches using compositionally adjusted
substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: uniprot_sprot.fasta
571,282 sequences; 206,678,396 total letters
Results from round 1
Query= YP_009725310.1 endoRNAse [Severe acute respiratory syndrome
coronavirus 2]
Length=346
Score E
Sequences producing significant alignments: (Bits) Value
sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute re... 716 0.0
sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute res... 656 0.0
sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus... 650 0.0
sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus... 633 0.0
sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus... 632 0.0
sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavir... 325 1e-99
sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavir... 325 2e-99
sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavir... 323 8e-99
sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavir... 323 9e-99
sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavi... 321 5e-98
sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus... 320 1e-97
sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus... 318 4e-97
sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavi... 318 8e-97
sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East res... 315 5e-96
sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus... 314 1e-95
sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus... 313 5e-95
sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavir... 311 2e-94
sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavi... 310 3e-94
sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavi... 310 3e-94
sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavir... 310 4e-94
sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavir... 306 7e-93
sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemi... 276 3e-82
sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus... 275 6e-82
sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavir... 271 9e-81
sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmi... 260 9e-77
sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavir... 258 6e-76
sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavir... 255 5e-75
sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectiou... 214 9e-61
sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious... 214 1e-60
sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious... 213 2e-60
sp|P18457|R1AB_CVPFS Replicase polyprotein 1ab (Fragment) OS=Porc... 172 4e-48
sp|P12723|R1AB_IBVK Replicase polyprotein 1ab (Fragment) OS=Avian... 118 2e-28
sp|P19811|RPOA_EAVBU Replicase polyprotein 1ab OS=Equine arteriti... 46.6 4e-04
sp|P0C6V8|R1AB_BRV1 Replicase polyprotein 1ab OS=Breda virus 1 OX... 46.2 4e-04
sp|A6YQT5|RPOA_PRRSV Replicase polyprotein 1ab OS=Porcine reprodu... 45.1 0.001
sp|Q8B912|RPOA_PRRSB Replicase polyprotein 1ab OS=Porcine reprodu... 43.9 0.002
sp|Q9YN02|RPOA_PRRS1 Replicase polyprotein 1ab OS=Porcine reprodu... 42.4 0.006
sp|Q9WJB2|RPOA_PRRSR Replicase polyprotein 1ab OS=Porcine reprodu... 41.6 0.013
sp|P0C6V7|R1AB_BEV Replicase polyprotein 1ab OS=Berne virus OX=11... 37.7 0.16
sp|Q68772|RPOA_SHFV Replicase polyprotein 1ab OS=Simian hemorrhag... 35.0 1.3
sp|B8J0P3|UPPP_DESDA Undecaprenyl-diphosphatase OS=Desulfovibrio ... 33.5 2.2
sp|A5N7P1|TRPA_CLOK5 Tryptophan synthase alpha chain OS=Clostridi... 32.3 5.1
sp|B9E152|TRPA_CLOK1 Tryptophan synthase alpha chain OS=Clostridi... 32.3 5.1
sp|Q11CB2|GLK_CHESB Glucokinase OS=Chelativorans sp. (strain BNC1... 32.3 7.3
sp|Q1RIG1|RS15_RICBR Small ribosomal subunit protein uS15 OS=Rick... 30.4 7.5
sp|A8GWV1|RS15_RICB8 Small ribosomal subunit protein uS15 OS=Rick... 30.4 7.5
sp|A4QGU3|Y2449_CORGB Putative hydro-lyase cgR_2449 OS=Corynebact... 31.6 8.9
sp|Q8NMM7|Y2544_CORGL Putative hydro-lyase Cgl2544/cg2803 OS=Cory... 31.6 9.3
>sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 GN=rep PE=1
SV=1
Length=7096
Score = 716 bits (1849), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 346/346 (100%), Positives = 346/346 (100%), Gaps = 0/346 (0%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK
Sbjct 6453 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 6512
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT
Sbjct 6513 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 6572
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYK 180
VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYK
Sbjct 6573 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYK 6632
Query 181 KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF 240
KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF
Sbjct 6633 KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF 6692
Query 241 SHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 300
SHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD
Sbjct 6693 SHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 6752
Query 301 DFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ
Sbjct 6753 DFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 6798
>sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus OX=694009 GN=rep PE=1 SV=1
Length=7073
Score = 656 bits (1692), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 307/346 (89%), Positives = 331/346 (96%), Gaps = 0/346 (0%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENVA+NVVNKGHFDG GE PVSIINN VYTKVDG+DVE+FENKTTLPVNVAFELWAK
Sbjct 6430 SLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAK 6489
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
RNIKPVPE+KILNNLGVDIAANTVIWDYKR+APAH+STIGVC+MTDIAKKPTE+ C+ LT
Sbjct 6490 RNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLT 6549
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYK 180
V FDGRV+GQVDLFRNARNGVLITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+K
Sbjct 6550 VLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFK 6609
Query 181 KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF 240
KVDG++QQLPETYFTQSR+L++FKPRSQME DFLELAMDEFI+RYKLEGYAFEHIVYGDF
Sbjct 6610 KVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDF 6669
Query 241 SHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 300
SH QLGGLHL+IGLAKR ++SP +LEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD
Sbjct 6670 SHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 6729
Query 301 DFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DFVEIIKSQDLSV+SKVVKVTIDY EISFMLWCKDGHVETFYPKLQ
Sbjct 6730 DFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQ 6775
>sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus
279/2005 OX=389167 GN=rep PE=3 SV=1
Length=7079
Score = 650 bits (1678), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 306/346 (88%), Positives = 330/346 (95%), Gaps = 0/346 (0%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENVA+NVVNKGHFDGQ GE PVSIINN VYTKVDG DVE+FENKTTLPVNVAFELWAK
Sbjct 6436 SLENVAYNVVNKGHFDGQIGEAPVSIINNAVYTKVDGNDVEIFENKTTLPVNVAFELWAK 6495
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
RNIKPVPE+KILNNLGVDIAANTVIWDYKR+APAH+STIGVC+MTDIAKKPTE+ C+ LT
Sbjct 6496 RNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLT 6555
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYK 180
V FDGRV+GQVDLFRNARNGVLITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+K
Sbjct 6556 VLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFK 6615
Query 181 KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF 240
KVDG++QQLPETYFTQSR+L++FKPRS+ME DFLELAMDEFI+RYKLEGYAFEHIVYGDF
Sbjct 6616 KVDGIIQQLPETYFTQSRDLEDFKPRSKMETDFLELAMDEFIQRYKLEGYAFEHIVYGDF 6675
Query 241 SHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 300
SH QLGGLHL+IGLAKR ++SP +LEDFIP DSTVKNYFITDAQTGSSKCVCSVIDLLLD
Sbjct 6676 SHGQLGGLHLMIGLAKRSQDSPLKLEDFIPTDSTVKNYFITDAQTGSSKCVCSVIDLLLD 6735
Query 301 DFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DFVEIIKSQDLSV+SKVVKVTIDY EISFMLWCKDGHVETFYPKLQ
Sbjct 6736 DFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQ 6781
>sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus
Rp3/2004 OX=349344 GN=rep PE=3 SV=1
Length=7071
Score = 633 bits (1632), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 306/346 (88%), Positives = 329/346 (95%), Gaps = 0/346 (0%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENVA+NVVNKGHFDGQ GE PVSIINN VYTKVDG DVE+FENKTTLPVNVAFELWAK
Sbjct 6428 SLENVAYNVVNKGHFDGQAGETPVSIINNAVYTKVDGFDVEIFENKTTLPVNVAFELWAK 6487
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
RNIK VPE+KILNNLGVDIAANTVIWD+KR+AP H+STIGVC+MTDIAKKPTE+ C+ LT
Sbjct 6488 RNIKSVPEIKILNNLGVDIAANTVIWDHKREAPVHMSTIGVCTMTDIAKKPTESACSSLT 6547
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYK 180
V FDGRV+GQVDLFRNARNGVLITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+K
Sbjct 6548 VLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFK 6607
Query 181 KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF 240
KVDG++QQLPETYFTQSR+L++FKPRSQME DFLELAMDEFI+RYKLEGYAFEHIVYGDF
Sbjct 6608 KVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDF 6667
Query 241 SHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 300
SH QLGGLHL+IGLAKR ++SP +LEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD
Sbjct 6668 SHGQLGGLHLMIGLAKRSRDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 6727
Query 301 DFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DFVEIIKSQDLSVVSKVVKVTIDY EISFMLWCKDGHVETFYPKLQ
Sbjct 6728 DFVEIIKSQDLSVVSKVVKVTIDYAEISFMLWCKDGHVETFYPKLQ 6773
>sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus
HKU3 OX=442736 GN=rep PE=3 SV=1
Length=7067
Score = 632 bits (1630), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 305/346 (88%), Positives = 328/346 (95%), Gaps = 0/346 (0%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENVA+NVVNKGHFDGQ GE PVSIINN VYTKVDG+DVE+FENKTTLPVNVAFELWAK
Sbjct 6424 SLENVAYNVVNKGHFDGQSGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAK 6483
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
RNIKPVPE+KILNNLGVDIAAN VIWDYKR+APAH+STIGVC+MTDIAKKPTE+ C+ L
Sbjct 6484 RNIKPVPEIKILNNLGVDIAANNVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLI 6543
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYK 180
V FDGRV+GQVD FRNARNGVLITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+K
Sbjct 6544 VLFDGRVEGQVDFFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFK 6603
Query 181 KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF 240
KVDG++QQLPETYFTQSR+L++FKPRSQME DFLELAMDEFI+RYKLEGYAFEHIVYGDF
Sbjct 6604 KVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDF 6663
Query 241 SHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 300
SH QLGGLHL+IGLAKR ++S +LEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD
Sbjct 6664 SHGQLGGLHLMIGLAKRSQDSLLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 6723
Query 301 DFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DFVEIIKSQDLSVVSKVVKVTIDY EISFMLWCKDGHVETFYPKLQ
Sbjct 6724 DFVEIIKSQDLSVVSKVVKVTIDYAEISFMLWCKDGHVETFYPKLQ 6769
>sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=rep PE=3 SV=1
Length=7152
Score = 325 bits (834), Expect = 1e-99, Method: Compositional matrix adjust.
Identities = 171/380 (45%), Positives = 236/380 (62%), Gaps = 40/380 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+VN GH+DG+ GE+P +I+N+ V K++ VD +F+N T+LP N+A EL+ K
Sbjct 6480 SLENVIYNLVNAGHYDGRIGELPCAIMNDKVVVKINNVDTVIFKNNTSLPTNIAVELFTK 6539
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+ PE+KIL NL +DI V+WDY +D+ ST GVC TD+ L
Sbjct 6540 RSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCSSTYGVCKYTDL------NFIENLN 6593
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGEA-VKTQFN 177
V FDGR +G ++ FR ARNGV I+ G + L GP++A LNGV + +GE V+ F
Sbjct 6594 VLFDGRDNGALEAFRKARNGVFISTGKLSSLSMIKGPQRADLNGVIVDKVGELNVEFWFA 6653
Query 178 YYKKVDGVVQQLPE-------------------------------TYFTQSRNLQEFKPR 206
K D V+ + T FTQSR L F+PR
Sbjct 6654 MRKDGDDVIFSRADSLSPSHYWSPQGNLGGNCAGNASGNDALARFTIFTQSRVLSTFEPR 6713
Query 207 SQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELE 266
S +E DF+++ FI +Y LE YAF+HIVYG F++ +GGLHLLIGL +R K+S ++
Sbjct 6714 SDLERDFIDMEDSLFIAKYGLEDYAFDHIVYGSFNYKVIGGLHLLIGLFRRLKKSNLVIQ 6773
Query 267 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTE 326
+F+ DS++ +YFITD + GSSK VC+VIDLLLDDFV I+KS +L+ VSKVV + +D+ +
Sbjct 6774 EFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDDFVVIVKSLNLNCVSKVVNINVDFKD 6833
Query 327 ISFMLWCKDGHVETFYPKLQ 346
FMLWC D + TFYPK+Q
Sbjct 6834 FQFMLWCNDNKIMTFYPKMQ 6853
>sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=rep PE=3 SV=1
Length=7132
Score = 325 bits (834), Expect = 2e-99, Method: Compositional matrix adjust.
Identities = 172/381 (45%), Positives = 239/381 (63%), Gaps = 42/381 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+VN GH+DG+ GE+P +I+N+ V K++ VD +F+N T+ P N+A EL+ K
Sbjct 6460 SLENVIYNLVNVGHYDGRTGELPCAIMNDKVVVKINNVDTVIFKNNTSFPTNIAVELFTK 6519
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+ PE+KIL NL +DI V+WDY +D+ ST GVC TD+ K E L
Sbjct 6520 RSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCSSTYGVCKYTDL--KFIEN----LN 6573
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGEAVKTQFNY 178
+ FDGR G ++ FR ARNGV I+ + L GP++A LNGV + +GE +K +F +
Sbjct 6574 ILFDGRDTGALEAFRKARNGVFISTEKLSRLSMIKGPQRADLNGVIVDKVGE-LKVEFWF 6632
Query 179 YKKVDG--VVQQLPE-------------------------------TYFTQSRNLQEFKP 205
+ DG V+ + T FTQSR L F+P
Sbjct 6633 AMRKDGDDVIFSRTDSLCSSHYWSPQGNLGGNCAGNVIGNDALTRFTIFTQSRVLSSFEP 6692
Query 206 RSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFEL 265
RS +E DF+++ + FI +Y LE YAF+HIVYG F+H +GGLHLLIGL +R K+S +
Sbjct 6693 RSDLERDFIDMDDNLFIAKYGLEDYAFDHIVYGSFNHKVIGGLHLLIGLFRRLKKSNLLI 6752
Query 266 EDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYT 325
++F+ DS++ +YFITD + GSSK VC+VIDLLLDDFV I+KS +LS VSKVV + +D+
Sbjct 6753 QEFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDDFVSIVKSLNLSCVSKVVNINVDFK 6812
Query 326 EISFMLWCKDGHVETFYPKLQ 346
+ FMLWC D + TFYPK+Q
Sbjct 6813 DFQFMLWCNDNKIMTFYPKMQ 6833
>sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=rep PE=3 SV=1
Length=7182
Score = 323 bits (829), Expect = 8e-99, Method: Compositional matrix adjust.
Identities = 172/381 (45%), Positives = 239/381 (63%), Gaps = 42/381 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+VN GH+DG+ GE+P +I+N+ V K++ VD +F+N T+ P N+A EL+ K
Sbjct 6510 SLENVIYNLVNVGHYDGRTGELPCAIMNDKVVVKINNVDTVIFKNNTSFPTNIAVELFTK 6569
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+ PE+KIL NL +DI V+WDY +D+ ST GVC TD+ K E L
Sbjct 6570 RSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCSSTYGVCKYTDL--KFIEN----LN 6623
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGEAVKTQFNY 178
+ FDGR G ++ FR ARNGV I+ + L GP++A LNGV + +GE +K +F +
Sbjct 6624 ILFDGRDTGALEAFRKARNGVFISTEKLSRLSMIKGPQRADLNGVIVDKVGE-LKVEFWF 6682
Query 179 YKKVDG--VVQQLPE-------------------------------TYFTQSRNLQEFKP 205
+ DG V+ + T FTQSR L F+P
Sbjct 6683 AMRKDGDDVIFSRTDSLCSSHYWSPQGNLGGNCAGNVIGNDALTRFTIFTQSRVLSSFEP 6742
Query 206 RSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFEL 265
RS +E DF+++ + FI +Y LE YAF+HIVYG F+H +GGLHLLIGL +R K+S +
Sbjct 6743 RSDLERDFIDMDDNLFIAKYGLEDYAFDHIVYGSFNHKVIGGLHLLIGLFRRKKKSNLLI 6802
Query 266 EDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYT 325
++F+ DS++ +YFITD + GSSK VC+VIDLLLDDFV I+KS +LS VSKVV + +D+
Sbjct 6803 QEFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDDFVSIVKSLNLSCVSKVVNINVDFK 6862
Query 326 EISFMLWCKDGHVETFYPKLQ 346
+ FMLWC D + TFYPK+Q
Sbjct 6863 DFQFMLWCNDNKIMTFYPKMQ 6883
>sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavirus
(strain 2) OX=76344 GN=rep PE=3 SV=1
Length=7124
Score = 323 bits (828), Expect = 9e-99, Method: Compositional matrix adjust.
Identities = 170/380 (45%), Positives = 239/380 (63%), Gaps = 40/380 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+VN GHFDG+ GE+P ++I V K+ DV +F+N T P NVA EL+AK
Sbjct 6452 SLENVVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVFKNNTPFPTNVAVELFAK 6511
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+P PE+K+ NL +D+ + V+WDY +D+ ST VC TD+ + E+ L
Sbjct 6512 RSIRPHPELKLFRNLNIDVCWSHVLWDYAKDSVFCSSTYKVCKYTDL--QCIES----LN 6565
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGEA-VKTQFN 177
V FDGR +G ++ F+ R+GV I +K L GP++A LNGV + +G++ V+ F
Sbjct 6566 VLFDGRDNGALEAFKKCRDGVYINTTKIKSLSMIKGPQRADLNGVVVEKVGDSDVEFWFA 6625
Query 178 YYKKVDGVV-----------QQLPE--------------------TYFTQSRNLQEFKPR 206
+ D V+ + P+ T FTQSR L F PR
Sbjct 6626 MRRDGDDVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEALARGTIFTQSRFLSSFAPR 6685
Query 207 SQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELE 266
S+ME DF++L D FI +Y L+ YAFEH+VYG F+ +GGLHLLIGLA+R ++S ++
Sbjct 6686 SEMEKDFMDLDEDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRQQKSNLVIQ 6745
Query 267 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTE 326
+F+P DS++ +YFITD +GSSK VC+VIDLLLDDFV+I+KS +L+ VSKVV V +D+ +
Sbjct 6746 EFVPYDSSIHSYFITDENSGSSKSVCTVIDLLLDDFVDIVKSLNLNCVSKVVNVNVDFKD 6805
Query 327 ISFMLWCKDGHVETFYPKLQ 346
FMLWC + V TFYP+LQ
Sbjct 6806 FQFMLWCNEEKVMTFYPRLQ 6825
>sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavirus
(strain A59) OX=11142 GN=rep PE=1 SV=1
Length=7176
Score = 321 bits (823), Expect = 5e-98, Method: Compositional matrix adjust.
Identities = 171/380 (45%), Positives = 237/380 (62%), Gaps = 40/380 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+VN GHFDG+ GE+P ++I V K+ DV +F+N T P NVA EL+AK
Sbjct 6504 SLENVVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVFKNNTPFPTNVAVELFAK 6563
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+P PE+K+ NL +D+ + V+WDY +D+ ST VC TD+ + E+ L
Sbjct 6564 RSIRPHPELKLFRNLNIDVCWSHVLWDYAKDSVFCSSTYKVCKYTDL--QCIES----LN 6617
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGEA-VKTQFN 177
V FDGR +G ++ F+ RNGV I +K L GP++A LNGV + +G++ V+ F
Sbjct 6618 VLFDGRDNGALEAFKKCRNGVYINTTKIKSLSMIKGPQRADLNGVVVEKVGDSDVEFWFA 6677
Query 178 YYKKVDGVV-----------QQLPE--------------------TYFTQSRNLQEFKPR 206
K D V+ + P+ T FTQSR L F PR
Sbjct 6678 VRKDGDDVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEALARGTIFTQSRLLSSFTPR 6737
Query 207 SQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELE 266
S+ME DF++L D FI +Y L+ YAFEH+VYG F+ +GGLHLLIGLA+R ++S ++
Sbjct 6738 SEMEKDFMDLDDDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRQQKSNLVIQ 6797
Query 267 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTE 326
+F+ DS++ +YFITD +GSSK VC+VIDLLLDDFV+I+KS +L VSKVV V +D+ +
Sbjct 6798 EFVTYDSSIHSYFITDENSGSSKSVCTVIDLLLDDFVDIVKSLNLKCVSKVVNVNVDFKD 6857
Query 327 ISFMLWCKDGHVETFYPKLQ 346
FMLWC + V TFYP+LQ
Sbjct 6858 FQFMLWCNEEKVMTFYPRLQ 6877
>sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus
HKU5 OX=694008 GN=rep PE=3 SV=1
Length=7182
Score = 320 bits (820), Expect = 1e-97, Method: Compositional matrix adjust.
Identities = 177/356 (50%), Positives = 232/356 (65%), Gaps = 17/356 (5%)
Query 2 LENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKR 61
LEN+A+NV+ +GHF G +GE+PV+++N+ +YTK D DV +FENKTTLP N+AFEL+AKR
Sbjct 6525 LENIAYNVIKQGHFTGVEGELPVAVVNDKIYTKSDVNDVCIFENKTTLPTNIAFELYAKR 6584
Query 62 NIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTV 121
++ P+ +L NL VD+ V+WDY+R +TIGVC TDI IC
Sbjct 6585 AVRSHPDFNLLRNLEVDVCYKFVLWDYERSNIYGSATIGVCKYTDIDVNSALNIC----- 6639
Query 122 FFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQ------ 175
FD R +G ++ F + NG+LI++ VK V A NG + +Q
Sbjct 6640 -FDIRDNGSLERFMSLPNGILISDRKVKNYPCIVSSNYAYFNGTLIRDNTGNSQSSDGEV 6698
Query 176 -----FNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGY 230
F YKKV+ Q +TY+T R + +F P S+ME DFL L D FI++YKLE Y
Sbjct 6699 KQPVTFYIYKKVNNEFVQFTDTYYTLGRTVSDFTPVSEMEKDFLALDSDVFIKKYKLEAY 6758
Query 231 AFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKC 290
AFEH+VYGDFS + LGGLHLLIGL K+ +E +E+ + +TV NYF+T++ T S K
Sbjct 6759 AFEHVVYGDFSRTTLGGLHLLIGLYKKHQEGHIIMEEMLKERATVHNYFVTESNTASFKA 6818
Query 291 VCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
VCSVIDL LDDFV+IIK+ DLSVVSKVVK+ ID T I FMLWCKDG V+TFYP+LQ
Sbjct 6819 VCSVIDLKLDDFVDIIKAMDLSVVSKVVKIPIDLTMIEFMLWCKDGQVQTFYPRLQ 6874
>sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus
133/2005 OX=389230 GN=rep PE=3 SV=1
Length=7126
Score = 318 bits (816), Expect = 4e-97, Method: Compositional matrix adjust.
Identities = 175/347 (50%), Positives = 227/347 (65%), Gaps = 8/347 (2%)
Query 2 LENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKR 61
LEN+AFNV+ +GHF G GE+PV+++N+ ++TK DV +F+N+T LP NVAFEL+AKR
Sbjct 6484 LENIAFNVIKQGHFTGVDGELPVAVVNDKIFTKNGTDDVCIFKNETALPTNVAFELYAKR 6543
Query 62 NIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTV 121
++ P++ +L NL VD+ N V+WDY R+ +TIGVC TDI P +C
Sbjct 6544 AVRSHPDLNLLRNLEVDVCYNFVLWDYDRNNIYGTTTIGVCKYTDIDVNPNLNMC----- 6598
Query 122 FFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGEAVKTQFNYY 179
FD R G ++ F + NGVLI++ +K +GPK A NG L I F Y
Sbjct 6599 -FDIRDKGSLERFMSMPNGVLISDRKIKNYPCIIGPKHAYFNGAILRNIDAKQPITFYLY 6657
Query 180 KKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGD 239
KKV+ +T++T R + +F + ME DFL L D FI++Y LE YAFEH+VYGD
Sbjct 6658 KKVNNEFVSFSDTFYTCGRTVNDFTALTPMEEDFLVLDSDVFIKKYSLEDYAFEHVVYGD 6717
Query 240 FSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLL 299
FSH+ LGGLHLLIGL K+ ++ +E+ + +TV NYFITD+ T S K VCSVIDL L
Sbjct 6718 FSHTTLGGLHLLIGLYKKMRDGHILMEEMLKDRATVHNYFITDSNTASYKAVCSVIDLRL 6777
Query 300 DDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DDFV IIK DL VVSKVVKV ID T I FMLWCKDG V+TFYP+LQ
Sbjct 6778 DDFVNIIKEMDLDVVSKVVKVPIDLTMIEFMLWCKDGKVQTFYPRLQ 6824
>sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavirus
(strain JHM) OX=11144 GN=rep PE=1 SV=1
Length=7180
Score = 318 bits (814), Expect = 8e-97, Method: Compositional matrix adjust.
Identities = 168/380 (44%), Positives = 236/380 (62%), Gaps = 40/380 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+VN GHFDG+ GE+P ++I V K+ DV +F+N T P NVA EL+A+
Sbjct 6508 SLENVVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVFKNNTPFPTNVAVELFAE 6567
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+P PE+K+ + + + N V+WDY +D+ ST VC TD+ + E+ L
Sbjct 6568 RSIRPHPELKLFRSSNIHVCWNHVLWDYAKDSVFCSSTYKVCKYTDL--QCIES----LN 6621
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGEA-VKTQFN 177
V FDGR +G ++ F+ RNGV I +K L GP++A LNGV + +G++ V+ F
Sbjct 6622 VLFDGRDNGALEAFKKCRNGVYINTTKIKSLSMIKGPQRADLNGVVVEKVGDSDVEFWFA 6681
Query 178 YYKKVDGVV-----------QQLPE--------------------TYFTQSRNLQEFKPR 206
+ D V+ + P+ T FTQSR L F PR
Sbjct 6682 MRRDGDDVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEALARGTIFTQSRFLSSFSPR 6741
Query 207 SQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELE 266
S+ME DF++L D FI +Y L+ YAFEH+VYG F+ +GGLHLLIGLA+R K+S ++
Sbjct 6742 SEMEKDFMDLDEDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRPKKSNLVIQ 6801
Query 267 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTE 326
+F+P DS++ +YFITD +GSS+ VC+VIDLLLDDFV+I+KS +L VSKVV V +D+ +
Sbjct 6802 EFVPYDSSIHSYFITDENSGSSESVCTVIDLLLDDFVDIVKSLNLKCVSKVVNVNVDFKD 6861
Query 327 ISFMLWCKDGHVETFYPKLQ 346
FMLWC + V TFYP+LQ
Sbjct 6862 FQFMLWCNEEKVMTFYPRLQ 6881
>sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East
respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=rep PE=1 SV=1
Length=7078
Score = 315 bits (808), Expect = 5e-96, Method: Compositional matrix adjust.
Identities = 176/348 (51%), Positives = 226/348 (65%), Gaps = 9/348 (3%)
Query 2 LENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKR 61
LEN+AFN V +GHF G +GE+PV+++N+ ++TK D+ +FENKTTLP N+AFEL+AKR
Sbjct 6434 LENIAFNFVKQGHFIGVEGELPVAVVNDKIFTKSGVNDICMFENKTTLPTNIAFELYAKR 6493
Query 62 NIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTV 121
++ P+ K+L+NL DI V+WDY+R +TIGVC TDI IC
Sbjct 6494 AVRSHPDFKLLHNLQADICYKFVLWDYERSNIYGTATIGVCKYTDIDVNSALNIC----- 6548
Query 122 FFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQ---FNY 178
FD R +G ++ F + N + I++ +K VGP A NG + V Q F
Sbjct 6549 -FDIRDNGSLEKFMSTPNAIFISDRKIKKYPCMVGPDYAYFNGAIIRDSDVVKQPVKFYL 6607
Query 179 YKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYG 238
YKKV+ E +TQSR+ +F P S ME DFL D FI++Y LE YAFEH+VYG
Sbjct 6608 YKKVNNEFIDPTECIYTQSRSCSDFLPLSDMEKDFLSFDSDVFIKKYGLENYAFEHVVYG 6667
Query 239 DFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLL 298
DFSH+ LGGLHLLIGL K+ +E +E+ + ST+ NYFIT+ T + K VCSVIDL
Sbjct 6668 DFSHTTLGGLHLLIGLYKKQQEGHIIMEEMLKGSSTIHNYFITETNTAAFKAVCSVIDLK 6727
Query 299 LDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
LDDFV I+KSQDL VVSKVVKV ID T I FMLWCKDG V+TFYP+LQ
Sbjct 6728 LDDFVMILKSQDLGVVSKVVKVPIDLTMIEFMLWCKDGQVQTFYPRLQ 6775
>sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus
HKU4 OX=694007 GN=rep PE=1 SV=1
Length=7119
Score = 314 bits (805), Expect = 1e-95, Method: Compositional matrix adjust.
Identities = 175/347 (50%), Positives = 226/347 (65%), Gaps = 8/347 (2%)
Query 2 LENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKR 61
LEN+AFNV+ +GHF G GE+PV+++N+ ++TK DV +F+N+T LP NVAFEL+AKR
Sbjct 6477 LENIAFNVIKQGHFTGVDGELPVAVVNDKIFTKNGTDDVCIFKNETALPTNVAFELYAKR 6536
Query 62 NIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTV 121
++ P++ +L NL VD+ N V+WDY R+ +TIGVC TDI P +C
Sbjct 6537 AVRSHPDLNLLRNLEVDVCYNFVLWDYDRNNIYGTTTIGVCKYTDIDVNPNLNMC----- 6591
Query 122 FFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGEAVKTQFNYY 179
FD R G ++ F + NGVLI++ +K GPK A NG L I F Y
Sbjct 6592 -FDIRDKGSLERFMSMPNGVLISDRKIKNYPCISGPKHAYFNGAILRNIDAKQPVIFYLY 6650
Query 180 KKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGD 239
KKV+ +T++T R + +F + ME DFL L D FI++Y LE YAFEH+VYGD
Sbjct 6651 KKVNNEFVSFSDTFYTCGRTVGDFTVLTPMEEDFLVLDSDVFIKKYGLEDYAFEHVVYGD 6710
Query 240 FSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLL 299
FSH+ LGGLHLLIGL K+ +E +E+ + +TV NYFITD+ T S K VCSVIDL L
Sbjct 6711 FSHTTLGGLHLLIGLYKKMREGHILMEEMLKDRATVHNYFITDSNTASYKAVCSVIDLRL 6770
Query 300 DDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DDFV IIK DL VVSKVVKV ID T I FMLWC+DG V+TFYP+LQ
Sbjct 6771 DDFVTIIKEMDLDVVSKVVKVPIDLTMIEFMLWCRDGKVQTFYPRLQ 6817
>sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus
HKU9 OX=694006 GN=rep PE=1 SV=1
Length=6930
Score = 313 bits (801), Expect = 5e-95, Method: Compositional matrix adjust.
Identities = 161/346 (47%), Positives = 217/346 (63%), Gaps = 9/346 (3%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENVA+NV+ GHF GE+PV+I+N+ +Y K DG D LF N T LP NVAFELWAK
Sbjct 6297 SLENVAYNVLKSGHFTAVAGELPVAILNDRLYIKEDGADKLLFTNNTCLPTNVAFELWAK 6356
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R++ VPEVK+L NLGV N VIWDY+ +AP +T+G+C+ TD+ K +
Sbjct 6357 RSVNVVPEVKLLRNLGVTCTYNLVIWDYESNAPLVPNTVGICTYTDLTKLDDQ------V 6410
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYK 180
V DGR F +N + + K + + GP AS+NGV + T F Y
Sbjct 6411 VLVDGRQLDAYSKFCQLKNAIYFSPSKPKCVC-TRGPTHASINGVVVEAPDRGTAFWYAM 6469
Query 181 KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF 240
+ DG Q + YFTQSR + +F+PR+Q+EIDFL+L F+++Y L EHIVYG F
Sbjct 6470 RKDGAFVQPTDGYFTQSRTVDDFQPRTQLEIDFLDLEQSCFLDKYDLHDLGLEHIVYGQF 6529
Query 241 SHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 300
+ +GGLHLLIG +R + + +E + D TV +Y + D T SSK VCSV+D++LD
Sbjct 6530 DGT-IGGLHLLIGAVRRKRTAHLVMETVLGTD-TVTSYAVIDQPTASSKQVCSVVDIILD 6587
Query 301 DFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DF+ +IK+QD SVVSKVV+ +D+ FMLWCK G + TFYP+LQ
Sbjct 6588 DFIALIKAQDRSVVSKVVQCCLDFKVFRFMLWCKGGKISTFYPQLQ 6633
>sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=rep PE=3 SV=1
Length=7059
Score = 311 bits (797), Expect = 2e-94, Method: Compositional matrix adjust.
Identities = 167/380 (44%), Positives = 232/380 (61%), Gaps = 40/380 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+V GH+ GQ GE+P +IIN+ V K+D DV +F N TT P NVA EL+AK
Sbjct 6422 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK 6481
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+ PE+K+ NL +D+ VIWDY R++ +T GVC TD+ + L
Sbjct 6482 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLK------LIDKLN 6535
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGE-------A 171
V FDGR +G ++ F+ + NGV I+ VK L GP +A LNGV + +G+ A
Sbjct 6536 VLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFA 6595
Query 172 VKTQ-----FNYYKKVDGVVQQLPE--------------------TYFTQSRNLQEFKPR 206
V+ + F+ + + Q P+ T FTQSR + F R
Sbjct 6596 VRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNEPGNVGGNDALATSTIFTQSRVISSFTCR 6655
Query 207 SQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELE 266
+ ME DF+ L D FI++Y LE YAFEHIVYG+F+ +GGLHLLIGL +R + S ++
Sbjct 6656 TDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQ 6715
Query 267 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTE 326
+F+ DS++ +YFITD ++G SK VC+VID+LLDDFV ++KS +L+ VSKVV V +D+ +
Sbjct 6716 EFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKD 6775
Query 327 ISFMLWCKDGHVETFYPKLQ 346
FMLWC D V TFYP+LQ
Sbjct 6776 FQFMLWCNDEKVMTFYPRLQ 6795
>sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=rep PE=3 SV=1
Length=7094
Score = 310 bits (794), Expect = 3e-94, Method: Compositional matrix adjust.
Identities = 167/380 (44%), Positives = 231/380 (61%), Gaps = 40/380 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+V GH+ GQ GE+P +IIN+ V K+D DV +F N TT P NVA EL+AK
Sbjct 6422 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK 6481
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+ PE+K+ NL +D+ VIWDY R++ +T GVC TD+ L
Sbjct 6482 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLK------FIDKLN 6535
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGE-------A 171
V FDGR +G ++ F+ + NGV I+ VK L GP +A LNGV + +G+ A
Sbjct 6536 VLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFA 6595
Query 172 VKTQ-----FNYYKKVDGVVQQLPE--------------------TYFTQSRNLQEFKPR 206
V+ + F+ + + Q P+ T FTQSR + F R
Sbjct 6596 VRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNEPGNVGGNDALATSTIFTQSRVISSFTCR 6655
Query 207 SQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELE 266
+ ME DF+ L D FI++Y LE YAFEHIVYG+F+ +GGLHLLIGL +R + S ++
Sbjct 6656 TDMEKDFIALDQDLFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQ 6715
Query 267 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTE 326
+F+ DS++ +YFITD ++G SK VC+VID+LLDDFV ++KS +L+ VSKVV V +D+ +
Sbjct 6716 EFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKD 6775
Query 327 ISFMLWCKDGHVETFYPKLQ 346
FMLWC D V TFYP+LQ
Sbjct 6776 FQFMLWCNDEKVMTFYPRLQ 6795
>sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=rep PE=3 SV=1
Length=7094
Score = 310 bits (794), Expect = 3e-94, Method: Compositional matrix adjust.
Identities = 167/380 (44%), Positives = 231/380 (61%), Gaps = 40/380 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+V GH+ GQ GE+P +IIN+ V K+D DV +F N TT P NVA EL+AK
Sbjct 6422 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK 6481
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+ PE+K+ NL +D+ VIWDY R++ +T GVC TD+ L
Sbjct 6482 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLK------FIDKLN 6535
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGE-------A 171
V FDGR +G ++ F+ + NGV I+ VK L GP +A LNGV + +G+ A
Sbjct 6536 VLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFA 6595
Query 172 VKTQ-----FNYYKKVDGVVQQLPE--------------------TYFTQSRNLQEFKPR 206
V+ + F+ + + Q P+ T FTQSR + F R
Sbjct 6596 VRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNEPGNVGGNDALATSTIFTQSRVISSFTCR 6655
Query 207 SQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELE 266
+ ME DF+ L D FI++Y LE YAFEHIVYG+F+ +GGLHLLIGL +R + S ++
Sbjct 6656 TDMEKDFIALDQDLFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQ 6715
Query 267 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTE 326
+F+ DS++ +YFITD ++G SK VC+VID+LLDDFV ++KS +L+ VSKVV V +D+ +
Sbjct 6716 EFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKD 6775
Query 327 ISFMLWCKDGHVETFYPKLQ 346
FMLWC D V TFYP+LQ
Sbjct 6776 FQFMLWCNDEKVMTFYPRLQ 6795
>sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavirus
OC43 OX=31631 GN=rep PE=1 SV=1
Length=7095
Score = 310 bits (794), Expect = 4e-94, Method: Compositional matrix adjust.
Identities = 167/381 (44%), Positives = 231/381 (61%), Gaps = 41/381 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+V GH+ GQ GE+P +IIN+ V TK+D DV +F N TT P NVA EL+AK
Sbjct 6422 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAK 6481
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+++ PE+K+ NL +D+ VIWDY R++ +T GVC TD+ L
Sbjct 6482 RSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLK------FIDKLN 6535
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGE-------A 171
V FDGR +G + F+ + NGV I+ VK L GP +A LNGV + +G+ A
Sbjct 6536 VLFDGRDNGAFEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFA 6595
Query 172 VKTQ-----FNYYKKVDGVVQQLPE---------------------TYFTQSRNLQEFKP 205
V+ + F+ + + Q P+ T FTQSR + F
Sbjct 6596 VRKEGQDVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSISTIFTQSRVISSFTC 6655
Query 206 RSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFEL 265
R+ ME DF+ L D FI++Y LE YAFEHIVYG+F+ +GGLHLLIGL +R + S +
Sbjct 6656 RTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVV 6715
Query 266 EDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYT 325
++F+ DS++ +YFITD ++G SK VC+VID+LLDDFV ++KS +L+ VSKVV V +D+
Sbjct 6716 QEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVTLVKSLNLNCVSKVVNVNVDFK 6775
Query 326 EISFMLWCKDGHVETFYPKLQ 346
+ FMLWC D V TFYP+LQ
Sbjct 6776 DFQFMLWCNDEKVMTFYPRLQ 6796
>sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=rep PE=3 SV=1
Length=7094
Score = 306 bits (784), Expect = 7e-93, Method: Compositional matrix adjust.
Identities = 166/380 (44%), Positives = 230/380 (61%), Gaps = 40/380 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+V GH+ GQ GE+P +IIN+ V K+D DV +F N TT P NVA EL+AK
Sbjct 6422 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK 6481
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+ PE+K+ NL +D+ VIWDY R++ +T GVC TD+ L
Sbjct 6482 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLK------FIDKLN 6535
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGE-------A 171
V FDGR +G ++ F+ + NGV I+ VK L GP +A LNGV + +G+ A
Sbjct 6536 VLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFA 6595
Query 172 VKTQ-----FNYYKKVDGVVQQLPE--------------------TYFTQSRNLQEFKPR 206
V+ + F+ + + Q P+ T FTQSR + F R
Sbjct 6596 VRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNEPGNVGGNDALATSTIFTQSRVISSFTCR 6655
Query 207 SQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELE 266
+ ME DF+ L D FI++Y LE YAFEHIVYG+F+ +GGLHLLIGL +R + S ++
Sbjct 6656 TDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQ 6715
Query 267 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTE 326
+F+ DS++ +YFITD ++G SK VC+VID+LLDDFV ++KS +L+ VSKVV V +D+ +
Sbjct 6716 EFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKD 6775
Query 327 ISFMLWCKDGHVETFYPKLQ 346
FMLWC D V TFY +LQ
Sbjct 6776 FQFMLWCNDEKVMTFYLRLQ 6795
>sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=rep PE=1 SV=1
Length=6781
Score = 276 bits (706), Expect = 3e-82, Method: Compositional matrix adjust.
Identities = 153/347 (44%), Positives = 207/347 (60%), Gaps = 11/347 (3%)
Query 2 LENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKR 61
LEN+AFNV+ KG F G +GE+PV+++N+ V + VD +F NKT+LP NVAFEL+AKR
Sbjct 6143 LENIAFNVLKKGSFVGDEGELPVAVVNDKVLVRDGTVDTLVFTNKTSLPTNVAFELYAKR 6202
Query 62 NIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTV 121
+ P + IL NLGV + VIWDY+ + P T VC TD +
Sbjct 6203 KVGLTPPITILRNLGVVCTSKCVIWDYEAERPLTTFTKDVCKYTDFE--------GDVCT 6254
Query 122 FFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNY-YK 180
FD + G ++ F +N VL++ +VK L + LNGV + K Y Y
Sbjct 6255 LFDNSIVGSLERFSMTQNAVLMSLTAVKKLT-GIKLTYGYLNGVPVNTHEDKPFTWYIYT 6313
Query 181 KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF 240
+ +G + P+ YFTQ R +F PRS ME DFL + M FI +Y LE Y FEH+VYGD
Sbjct 6314 RKNGKFEDYPDGYFTQGRTTADFSPRSDMEKDFLSMDMGLFINKYGLEDYGFEHVVYGDV 6373
Query 241 SHSQLGGLHLLIGLAKRFKESPFELEDFIPM-DSTVKNYFITDAQTGSSKCVCSVIDLLL 299
S + LGGLHLLI + ++++F+ DST+K+ +T A SSK VC+ +DLLL
Sbjct 6374 SKTTLGGLHLLISQVRLACMGVLKIDEFVSSNDSTLKSCTVTYADNPSSKMVCTYMDLLL 6433
Query 300 DDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DDFV I+KS DLSVVSKV +V +D +MLWCKD ++TFYP+LQ
Sbjct 6434 DDFVSILKSLDLSVVSKVHEVMVDCKMWRWMLWCKDHKLQTFYPQLQ 6480
>sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus
512/2005 OX=693999 GN=rep PE=3 SV=1
Length=6793
Score = 275 bits (703), Expect = 6e-82, Method: Compositional matrix adjust.
Identities = 159/348 (46%), Positives = 209/348 (60%), Gaps = 13/348 (4%)
Query 2 LENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGV-DVELFENKTTLPVNVAFELWAK 60
LEN+A+NVV KG F G +GE+PV+++N+ V + DGV D +F N T+LP NVAFEL+AK
Sbjct 6155 LENIAYNVVKKGSFVGVEGELPVAVVNDKVMVR-DGVSDNVVFVNNTSLPTNVAFELYAK 6213
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R + P + IL NLGV + V+WDY+ P T VC TD +
Sbjct 6214 RKVGLTPPLTILKNLGVVCTSKCVLWDYEASRPLTTFTKDVCKYTDFD--------GDVC 6265
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNY-Y 179
FD V G + F +N VLI+ +VK L ++ LNGV + K Y Y
Sbjct 6266 TLFDNSVPGAFERFTVTKNAVLISLTAVKKLT-AIKLTYGYLNGVPVFTHEDKPFTWYIY 6324
Query 180 KKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGD 239
+ DG + P+ YFTQ R + +F+PRS ME DFL + M FI +Y LE Y FEH+V+GD
Sbjct 6325 TRKDGAFVEYPDGYFTQGRVISDFQPRSNMEEDFLNMDMGLFISKYGLEDYGFEHVVFGD 6384
Query 240 FSHSQLGGLHLLIGLAKRFKESPFELEDFI-PMDSTVKNYFITDAQTGSSKCVCSVIDLL 298
S + LGGLHLLI + K ++EDF+ DST+K+ +T SSK VC+ +DLL
Sbjct 6385 VSKTTLGGLHLLISQIRLSKIGVLKVEDFVSSSDSTLKSCTVTYVDNPSSKMVCTYVDLL 6444
Query 299 LDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
LDDFV I+KS DLSVVSKV +V ID +MLWCKD V+TFYP+LQ
Sbjct 6445 LDDFVNILKSVDLSVVSKVHEVVIDCKVWRWMLWCKDHKVQTFYPQLQ 6492
>sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavirus
NL63 OX=277944 GN=rep PE=1 SV=1
Length=6729
Score = 271 bits (694), Expect = 9e-81, Method: Compositional matrix adjust.
Identities = 156/353 (44%), Positives = 208/353 (59%), Gaps = 16/353 (5%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLEN+AFNVV KG F G GE+PV+++N+ V+ + VD +F NKTTLP NVAFEL+AK
Sbjct 6086 SLENIAFNVVKKGCFTGVDGELPVAVVNDKVFVRYGDVDNLVFTNKTTLPTNVAFELFAK 6145
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R + P + IL NLGV V+WDY+ + P T VC TD E +C
Sbjct 6146 RKMGLTPPLSILKNLGVVATYKFVLWDYEAERPFTSYTKSVCKYTDF----NEDVC---- 6197
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIG----EAVKTQF 176
V FD + G + F N VL + +K L P + LNG+ + + V+
Sbjct 6198 VCFDNSIQGSYERFTLTTNAVLFSTVVIKNLTP-IKLNFGMLNGMPVSSIKGDKGVEKLV 6256
Query 177 NYYKKV--DGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEH 234
N+Y V +G Q + ++TQ RNL +F PRS ME DFL + M FI +Y LE + FEH
Sbjct 6257 NWYIYVRKNGQFQDHYDGFYTQGRNLSDFTPRSDMEYDFLNMDMGVFINKYGLEDFNFEH 6316
Query 235 IVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPM-DSTVKNYFITDAQTGSSKCVCS 293
+VYGD S + LGGLHLLI + K + +DF+ D+T++ +T SSK VC+
Sbjct 6317 VVYGDVSKTTLGGLHLLISQFRLSKMGVLKADDFVTASDTTLRCCTVTYLNELSSKVVCT 6376
Query 294 VIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
+DLLLDDFV I+KS DL V+SKV +V ID +MLWCKD H+ TFYP+LQ
Sbjct 6377 YMDLLLDDFVTILKSLDLGVISKVHEVIIDNKPYRWMLWCKDNHLSTFYPQLQ 6429
>sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=rep PE=1 SV=1
Length=6684
Score = 260 bits (664), Expect = 9e-77, Method: Compositional matrix adjust.
Identities = 152/349 (44%), Positives = 215/349 (62%), Gaps = 13/349 (4%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENVAFNVV KG F G +G++P ++I + + + D +F NKT+LP NVAFEL+AK
Sbjct 6046 SLENVAFNVVKKGAFTGLKGDLPTAVIADKIMVRDGPTDKCIFTNKTSLPTNVAFELYAK 6105
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R + P + IL NLGV V+WDY+ + P T VCS TD+ + +
Sbjct 6106 RKLGLTPPLTILRNLGVVATYKFVLWDYEAERPFSNFTKQVCSYTDLDSE--------VV 6157
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNG--VTLIGEAVKTQFNY 178
FD + G + F R+ VLI+ +VKGL ++ + LN V+ +G T + Y
Sbjct 6158 TCFDNSIAGSFERFTTTRDAVLISNNAVKGLS-AIKLQYGLLNDLPVSTVGNKPVTWYIY 6216
Query 179 YKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYG 238
+K V+Q+ ++Y+TQ R + FKPRS ME DFL + FI++Y LE Y FEH+V+G
Sbjct 6217 VRKNGEYVEQI-DSYYTQGRTFETFKPRSTMEEDFLSMDTTLFIQKYGLEDYGFEHVVFG 6275
Query 239 DFSHSQLGGLHLLIGLAKRFKESPFELEDFI-PMDSTVKNYFITDAQTGSSKCVCSVIDL 297
D S + +GG+HLLI + K F +++F+ DST+K+ IT A SSK VC+ +D+
Sbjct 6276 DVSKTTIGGMHLLISQVRLAKMGLFSVQEFMNNSDSTLKSCCITYADDPSSKNVCTYMDI 6335
Query 298 LLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
LLDDFV IIKS DL+VVSKVV V +D +MLWC++ H++TFYP+LQ
Sbjct 6336 LLDDFVTIIKSLDLNVVSKVVDVIVDCKAWRWMLWCENSHIKTFYPQLQ 6384
>sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavirus
229E OX=11137 GN=rep PE=1 SV=1
Length=6758
Score = 258 bits (658), Expect = 6e-76, Method: Compositional matrix adjust.
Identities = 154/357 (43%), Positives = 205/357 (57%), Gaps = 22/357 (6%)
Query 2 LENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKR 61
LEN+AFNVVNKG F G GE+PV+I + V+ + D +F NKT+LP N+AFEL+AKR
Sbjct 6112 LENIAFNVVNKGSFVGADGELPVAISGDKVFVRDGNTDNLVFVNKTSLPTNIAFELFAKR 6171
Query 62 NIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTV 121
+ P + IL NLGV V+WDY+ + P T VC TD A E +C
Sbjct 6172 KVGLTPPLSILKNLGVVATYKFVLWDYEAERPLTSFTKSVCGYTDFA----EDVCTC--- 6224
Query 122 FFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKT------- 174
+D + G + F + N VL + +VK S+ LN L G A+ T
Sbjct 6225 -YDNSIQGSYERFTLSTNAVLFSATAVKTGGKSL--PAIKLNFGMLNGNAIATVKSEDGN 6281
Query 175 --QFNY--YKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGY 230
N+ Y + DG + ++TQ RNLQ+F PRS ME DFL + + FI++Y LE +
Sbjct 6282 IKNINWFVYVRKDGKPVDHYDGFYTQGRNLQDFLPRSTMEEDFLNMDIGVFIQKYGLEDF 6341
Query 231 AFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPM-DSTVKNYFITDAQTGSSK 289
FEH+VYGD S + LGGLHLLI + K + E+F+ D T+K +T SSK
Sbjct 6342 NFEHVVYGDVSKTTLGGLHLLISQVRLSKMGILKAEEFVAASDITLKCCTVTYLNDPSSK 6401
Query 290 CVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
VC+ +DLLLDDFV ++KS DL+VVSKV +V ID +MLWCKD V TFYP+LQ
Sbjct 6402 TVCTYMDLLLDDFVSVLKSLDLTVVSKVHEVIIDNKPWRWMLWCKDNAVATFYPQLQ 6458
>sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavirus
(strain FIPV WSU-79/1146) OX=33734 GN=rep PE=1 SV=2
Length=6709
Score = 255 bits (651), Expect = 5e-75, Method: Compositional matrix adjust.
Identities = 149/349 (43%), Positives = 213/349 (61%), Gaps = 13/349 (4%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENVAFNVV KG F G +G++P ++I + + + D +F NKT+LP NVAFEL+AK
Sbjct 6071 SLENVAFNVVKKGAFTGLKGDLPTAVIADKIMVRDGPTDKCIFTNKTSLPTNVAFELYAK 6130
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R + P + IL NLGV V+WDY+ + P T VCS TD+ + +
Sbjct 6131 RKLGLTPPLTILRNLGVVATYKFVLWDYEAECPFSNFTKQVCSYTDLDSE--------VV 6182
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNG--VTLIGEAVKTQFNY 178
FD + G + F ++ VLI+ +VKGL ++ + LN V+ +G T + Y
Sbjct 6183 TCFDNSIAGSFERFTTTKDAVLISNNAVKGLS-AIKLQYGFLNDLPVSTVGNKPVTWYIY 6241
Query 179 YKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYG 238
+K V+Q+ ++Y+T R + FKPRS ME DFL + FI++Y LE Y FEH+V+G
Sbjct 6242 VRKNGEYVEQI-DSYYTHGRTFETFKPRSTMEEDFLSMDTTLFIQKYGLEDYGFEHVVFG 6300
Query 239 DFSHSQLGGLHLLIGLAKRFKESPFELEDFIP-MDSTVKNYFITDAQTGSSKCVCSVIDL 297
D S + +GG+HLLI + K F +++F+ DST+K+ IT A SSK VC+ +D+
Sbjct 6301 DVSKTTIGGMHLLISQVRLAKMGLFSVQEFMTNSDSTLKSCCITYADDPSSKNVCTYMDI 6360
Query 298 LLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
LLDDFV IIKS DL+VVSKVV V +D +MLWC++ ++TFYP+LQ
Sbjct 6361 LLDDFVTIIKSLDLNVVSKVVDVIVDCKAWRWMLWCENSQIKTFYPQLQ 6409
>sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=rep
PE=3 SV=1
Length=6629
Score = 214 bits (544), Expect = 9e-61, Method: Compositional matrix adjust.
Identities = 139/352 (39%), Positives = 200/352 (57%), Gaps = 20/352 (6%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
S++N+A+N+ GH+D GE+P I + V+ GV+ +F N+TTLP +VAFEL+AK
Sbjct 5990 SIDNIAYNMYKGGHYDAIAGEMPTVITGDKVFVIDQGVEKAVFVNQTTLPTSVAFELYAK 6049
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
RNI+ +P +IL LGVD+ VIWDY P + +T+ VC+ TDI L
Sbjct 6050 RNIRTLPNNRILKGLGVDVTNGFVIWDYANQTPLYRNTVKVCAYTDIEPN-------GLV 6102
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL-NGVTLIGEAVKTQFNYY 179
V +D R G F A N VL++ K P + NG+ L A Y
Sbjct 6103 VLYDDRY-GDYQSFLAADNAVLVSTQCYKRYSYVEIPSNLLVQNGMPLKDGA---NLYVY 6158
Query 180 KKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGD 239
K+V+G LP T TQ R+ + F+PRS +E DFL ++ + F+ERY + +HI+YG+
Sbjct 6159 KRVNGAFVTLPNTINTQGRSYETFEPRSDIERDFLAMSEESFVERYG-KDLGLQHILYGE 6217
Query 240 FSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTV-KNYFITDAQTGSSKCVCSVIDLL 298
QLGGLH +IG+ + + + + DS V +NYF+ + GS K VC+V+DLL
Sbjct 6218 VDKPQLGGLHTVIGMYRLLRANKLNAKSVTNSDSDVMQNYFVL-SDNGSYKQVCTVVDLL 6276
Query 299 LDDFV----EIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
LDDF+ I+K + SKVV V+IDY I+FM W +DG ++T YP+LQ
Sbjct 6277 LDDFLELLRNILKEYGTN-KSKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQ 6327
>sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=rep PE=1
SV=1
Length=6629
Score = 214 bits (544), Expect = 1e-60, Method: Compositional matrix adjust.
Identities = 139/352 (39%), Positives = 200/352 (57%), Gaps = 20/352 (6%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
S++N+A+N+ GH+D GE+P I + V+ GV+ +F N+TTLP +VAFEL+AK
Sbjct 5990 SIDNIAYNMYKGGHYDAIAGEMPTVITGDKVFVIDQGVEKAVFVNQTTLPTSVAFELYAK 6049
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
RNI+ +P +IL LGVD+ VIWDY P + +T+ VC+ TDI L
Sbjct 6050 RNIRTLPNNRILKGLGVDVTNGFVIWDYANQTPLYRNTVKVCAYTDIEPN-------GLV 6102
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL-NGVTLIGEAVKTQFNYY 179
V +D R G F A N VL++ K P + NG+ L A Y
Sbjct 6103 VLYDDRY-GDYQSFLAADNAVLVSTQCYKRYSYVEIPSNLLVQNGMPLKDGA---NLYVY 6158
Query 180 KKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGD 239
K+V+G LP T TQ R+ + F+PRS +E DFL ++ + F+ERY + +HI+YG+
Sbjct 6159 KRVNGAFVTLPNTINTQGRSYETFEPRSDIERDFLAMSEESFVERYG-KDLGLQHILYGE 6217
Query 240 FSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTV-KNYFITDAQTGSSKCVCSVIDLL 298
QLGGLH +IG+ + + + + DS V +NYF+ + GS K VC+V+DLL
Sbjct 6218 VDKPQLGGLHTVIGMYRLLRANKLNAKSVTNSDSDVMQNYFVL-SDNGSYKQVCTVVDLL 6276
Query 299 LDDFV----EIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
LDDF+ I+K + SKVV V+IDY I+FM W +DG ++T YP+LQ
Sbjct 6277 LDDFLELLRNILKEYGTN-KSKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQ 6327
>sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=rep PE=1 SV=1
Length=6631
Score = 213 bits (541), Expect = 2e-60, Method: Compositional matrix adjust.
Identities = 138/352 (39%), Positives = 200/352 (57%), Gaps = 20/352 (6%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
S++N+A+N+ GH+D GE+P + + V+ GV+ +F N+T LP +VAFEL+AK
Sbjct 5992 SIDNIAYNMYKGGHYDAIAGEMPTIVTGDKVFVIDQGVEKAVFFNQTILPTSVAFELYAK 6051
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
RNI+ +P +IL LGVD+ VIWDY P + +T+ VC+ TDI L
Sbjct 6052 RNIRTLPNNRILKGLGVDVTNGFVIWDYTNQTPLYRNTVKVCAYTDIEPN-------GLI 6104
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL-NGVTLIGEAVKTQFNYY 179
V +D R G F A N VL++ K P + NG+ L A Y
Sbjct 6105 VLYDDRY-GDYQSFLAADNAVLVSTQCYKRYSYVEIPSNLLVQNGIPLKDGA---NLYVY 6160
Query 180 KKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGD 239
K+V+G LP T TQ R+ + F+PRS +E DFL+++ + F+E+Y E +HI+YG+
Sbjct 6161 KRVNGAFVTLPNTLNTQGRSYETFEPRSDVERDFLDMSEESFVEKYGKE-LGLQHILYGE 6219
Query 240 FSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTV-KNYFITDAQTGSSKCVCSVIDLL 298
QLGGLH +IG+ + + + + DS V +NYF+ A GS K VC+V+DLL
Sbjct 6220 VDKPQLGGLHTVIGMCRLLRANKLNAKSVTNSDSDVMQNYFVL-ADNGSYKQVCTVVDLL 6278
Query 299 LDDFV----EIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
LDDF+ I+K + SKVV V+IDY I+FM W +DG ++T YP+LQ
Sbjct 6279 LDDFLELLRNILKEYGTN-KSKVVTVSIDYHSINFMAWFEDGIIKTCYPQLQ 6329
>sp|P18457|R1AB_CVPFS Replicase polyprotein 1ab (Fragment) OS=Porcine
transmissible gastroenteritis coronavirus (strain FS772/70)
OX=11150 GN=rep PE=3 SV=1
Length=533
Score = 172 bits (437), Expect = 4e-48, Method: Compositional matrix adjust.
Identities = 101/227 (44%), Positives = 145/227 (64%), Gaps = 5/227 (2%)
Query 123 FDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNG--VTLIGEAVKTQFNYYK 180
FD + G + F R+ VLI+ +VKGL ++ + LN V+ +G T + Y +
Sbjct 9 FDNSIAGSFERFTTTRDAVLISNNAVKGLS-AIKLQYGLLNDLPVSTVGNKPVTWYIYVR 67
Query 181 KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF 240
K V+Q+ ++Y+TQ R + FKPRS ME DFL + FI++Y LE Y FEH+V+GD
Sbjct 68 KNGEYVEQI-DSYYTQGRTFETFKPRSTMEEDFLSMDTTLFIQKYGLEDYGFEHVVFGDV 126
Query 241 SHSQLGGLHLLIGLAKRFKESPFELEDFIP-MDSTVKNYFITDAQTGSSKCVCSVIDLLL 299
S + +GG+HLLI + K F +++F+ DST+K+ IT A SSK VC+ +D+LL
Sbjct 127 SKTTIGGMHLLISQVRLAKMGLFSVQEFMNNSDSTLKSCCITYADDPSSKNVCTYMDILL 186
Query 300 DDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DDFV IIKS DL+VVSKVV V +D +MLWC++ H++TFYP+LQ
Sbjct 187 DDFVTIIKSLDLNVVSKVVDVIVDCKAWKWMLWCENSHIKTFYPQLQ 233
>sp|P12723|R1AB_IBVK Replicase polyprotein 1ab (Fragment) OS=Avian
infectious bronchitis virus (strain KB8523) OX=11126 GN=rep
PE=3 SV=1
Length=521
Score = 118 bits (296), Expect = 2e-28, Method: Compositional matrix adjust.
Identities = 74/172 (43%), Positives = 112/172 (65%), Gaps = 6/172 (3%)
Query 179 YKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYG 238
YK+V+G LP T TQ R+ + F+PRS +E DFL+++ ++F+E+Y + +HI+YG
Sbjct 50 YKRVNGAFVTLPNTLNTQGRSYETFEPRSDVERDFLDMSEEDFVEKYG-KDLGLQHILYG 108
Query 239 DFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTV-KNYFITDAQTGSSKCVCSVIDL 297
+ QLGGLH +IG+ + + + + DS V +NYF+ A GS K VC+V+DL
Sbjct 109 EVDKPQLGGLHTVIGMYRLLRANKLNAKSVTNSDSDVMQNYFVL-ADNGSYKQVCTVVDL 167
Query 298 LLDDFVEI---IKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
LLDDF+E+ I ++ + SKVV V+IDY I+FM W +DG ++T YP+LQ
Sbjct 168 LLDDFLELLRNILNEYGTNKSKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQ 219
>sp|P19811|RPOA_EAVBU Replicase polyprotein 1ab OS=Equine arteritis
virus (strain Bucyrus) OX=299386 GN=rep PE=1 SV=3
Length=3175
Score = 46.6 bits (109), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 40/160 (25%), Positives = 70/160 (44%), Gaps = 30/160 (19%)
Query 174 TQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFE 233
T + + VDG + LP++ F+ R F+ S+ FL+ A ++F A
Sbjct 2917 TSYWLTEWVDGKARALPDSLFSSGR----FETNSRA---FLDEAEEKFAA-------AHP 2962
Query 234 HIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTG-SSKCVC 292
H G+ + S +GG H + F + L +P D+ + + G ++K C
Sbjct 2963 HACLGEINKSTVGGSHFI------FSQ---YLPPLLPADAVA---LVGASLAGKAAKAAC 3010
Query 293 SVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLW 332
SV+D+ F + + L S+V K+ ID+ M+W
Sbjct 3011 SVVDVYAPSFEPYLHPETL---SRVYKIMIDFKPCRLMVW 3047
>sp|P0C6V8|R1AB_BRV1 Replicase polyprotein 1ab OS=Breda virus
1 OX=360393 GN=rep PE=2 SV=1
Length=6733
Score = 46.2 bits (108), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 54/189 (29%), Positives = 91/189 (48%), Gaps = 28/189 (15%)
Query 164 GVTLIGEAVKTQFNYYKKVDG--VVQQLPETYFTQSR--NLQEFKPRSQMEIDFLELAMD 219
V + EA Q YY ++ +++LPET F+ R NL E P + +LA++
Sbjct 6300 SVHIYVEATGEQPLYYLQLGNGESLRELPETLFSTGRLYNL-EHDPSKNFNVQ--QLAIE 6356
Query 220 EFIERYKLEGYAFEHIVYGDFSH--SQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKN 277
+ + H+ GDF+ + +GG+H ++ L +K S IP + VK
Sbjct 6357 TIPKNH--------HVFAGDFTDVGTDIGGVHHVVAL-NGYKGS------IIP--NYVKP 6399
Query 278 YFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV-VSKVVKVTIDYTEISFMLWCK-D 335
G S +++D+ + E +K Q V VSKV+ V ID+ E+ FM++ K +
Sbjct 6400 IATGLINVGRSVKRTTLVDVCANQLYEKVKQQIAGVKVSKVIFVNIDFQEVQFMVFAKGE 6459
Query 336 GHVETFYPK 344
++TFYP+
Sbjct 6460 DDIQTFYPQ 6468
>sp|A6YQT5|RPOA_PRRSV Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus OX=28344 PE=1 SV=2
Length=3931
Score = 45.1 bits (105), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 48/191 (25%), Positives = 80/191 (42%), Gaps = 34/191 (18%)
Query 148 VKGLQPSVGPKQASLNGVTLIGEAV----KTQFNYY--KKVDGVVQQLPETYFTQSRNLQ 201
V L+P +A + ++G +V +YY K V G Q LPET F+ R
Sbjct 3606 VASLRPIHKYSRACIGAGYMVGPSVFLGTPGVVSYYLTKFVRGEAQVLPETVFSTGR--- 3662
Query 202 EFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKES 261
+E+D E D ER E + H GD + +GG H + ++
Sbjct 3663 -------IEVDCREYLDDR--EREVAE--SLPHAFIGDVKGTTVGGCH---HVTSKY--- 3705
Query 262 PFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVT 321
L F+P +S + + ++K VC++ D+ L D + + S+ KV
Sbjct 3706 ---LPRFLPKESVAVVGVSSPGK--AAKAVCTLTDVYLPDLEAYLHPE---TQSRCWKVM 3757
Query 322 IDYTEISFMLW 332
+D+ E+ M+W
Sbjct 3758 LDFKEVRLMVW 3768
>sp|Q8B912|RPOA_PRRSB Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain HB-1) OX=300563
GN=rep PE=2 SV=3
Length=3961
Score = 43.9 bits (102), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 48/191 (25%), Positives = 79/191 (41%), Gaps = 34/191 (18%)
Query 148 VKGLQPSVGPKQASLNGVTLIGEAV----KTQFNYY--KKVDGVVQQLPETYFTQSRNLQ 201
V L+P +A + ++G +V +YY K V G Q LPET F+ R
Sbjct 3636 VASLRPIHKYSRACIGAGYMVGPSVFLGTPGVVSYYLTKFVRGEAQVLPETVFSTGR--- 3692
Query 202 EFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKES 261
+E+D E D ER E + H GD + +GG H + ++
Sbjct 3693 -------IEVDCREYLDDR--EREVAE--SLPHAFIGDVKGTTVGGCH---HVTSKY--- 3735
Query 262 PFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVT 321
L F+P +S + + ++K C++ D+ L D + + SK KV
Sbjct 3736 ---LPRFLPKESVAVVGVSSPGE--AAKAFCTLTDVYLPDLEAYLHPE---TQSKCWKVM 3787
Query 322 IDYTEISFMLW 332
+D+ E+ M+W
Sbjct 3788 LDFKEVRLMVW 3798
>sp|Q9YN02|RPOA_PRRS1 Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain 16244B) OX=300561
GN=rep PE=1 SV=3
Length=3961
Score = 42.4 bits (98), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 45/191 (24%), Positives = 78/191 (41%), Gaps = 34/191 (18%)
Query 148 VKGLQPSVGPKQASLNGVTLIGEAV----KTQFNYY--KKVDGVVQQLPETYFTQSRNLQ 201
V L+P +A + ++G +V +YY K V G Q LPET F+ R
Sbjct 3636 VASLRPIHKYSRACIGAGYMVGPSVFLGTPGVVSYYLTKFVKGEAQLLPETVFSTGR--- 3692
Query 202 EFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKES 261
+E+D E D R + + H GD + +GG H + R+
Sbjct 3693 -------IEVDCREYLDD----REREVAASLPHAFIGDVKGTTVGGCH---HVTSRY--- 3735
Query 262 PFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVT 321
L +P +S + + ++K +C++ D+ L D + + SK K+
Sbjct 3736 ---LPRVLPKESVAVVGVSSPGK--AAKALCTLTDVYLPDLEAYLHPE---TQSKCWKMM 3787
Query 322 IDYTEISFMLW 332
+D+ E+ M+W
Sbjct 3788 LDFKEVRLMVW 3798
>sp|Q9WJB2|RPOA_PRRSR Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain VR-2332) OX=300559
GN=rep PE=1 SV=2
Length=3960
Score = 41.6 bits (96), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 45/191 (24%), Positives = 78/191 (41%), Gaps = 34/191 (18%)
Query 148 VKGLQPSVGPKQASLNGVTLIGEAV----KTQFNYY--KKVDGVVQQLPETYFTQSRNLQ 201
V L+P +A + ++G +V +YY K V G Q LPET F+ R
Sbjct 3635 VASLRPIHKYSRACIGAGYMVGPSVFLGTPGVVSYYLTKFVKGGAQVLPETVFSTGR--- 3691
Query 202 EFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKES 261
+E+D E D R + + H GD + +GG H + R+
Sbjct 3692 -------IEVDCREYLDD----REREVAASLPHGFIGDVKGTTVGGCH---HVTSRY--- 3734
Query 262 PFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVT 321
L +P +S + + ++K +C++ D+ L D + + SK K+
Sbjct 3735 ---LPRVLPKESVAVVGVSSPGK--AAKALCTLTDVYLPDLEAYLHPE---TQSKCWKMM 3786
Query 322 IDYTEISFMLW 332
+D+ E+ M+W
Sbjct 3787 LDFKEVRLMVW 3797
>sp|P0C6V7|R1AB_BEV Replicase polyprotein 1ab OS=Berne virus OX=11156
GN=rep PE=1 SV=1
Length=6857
Score = 37.7 bits (86), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 41/161 (25%), Positives = 76/161 (47%), Gaps = 22/161 (14%)
Query 188 QLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSH--SQL 245
+LP+T F+ R L + + +LA++ + H+ GDF+ + +
Sbjct 6450 ELPDTLFSTGR-LYNLDHDAAQNFNVKQLAIETMPNNH--------HVFSGDFTEVGTDI 6500
Query 246 GGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEI 305
GG+H ++ L +K S IP + VK G + +++D+ + E
Sbjct 6501 GGVHHVVAL-NGYKGS------IIP--NYVKPIATGLINVGRAVKRTTLVDVCANQLYEK 6551
Query 306 IKSQDLSV-VSKVVKVTIDYTEISFMLWCK-DGHVETFYPK 344
+K Q V VSKV+ V ID+ ++ FM++ + ++TFYP+
Sbjct 6552 VKQQLEGVKVSKVIFVNIDFQDVQFMVFANGEDDIQTFYPQ 6592
>sp|Q68772|RPOA_SHFV Replicase polyprotein 1ab OS=Simian hemorrhagic
fever virus OX=38143 GN=rep PE=2 SV=4
Length=3595
Score = 35.0 bits (79), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 33/129 (26%), Positives = 54/129 (42%), Gaps = 24/129 (19%)
Query 206 RSQMEI-DFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFE 264
R +M+I D+L+ A +F ++ H GD + +GG H +
Sbjct 3303 RFEMDIRDYLDSAERDFAAKH-------PHAFIGDTKGTTVGGCHHITSQ---------Y 3346
Query 265 LEDFIPMDSTVKNYFITDAQTG-SSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTID 323
L +P DS VK + ++ G + K +C+V D+ L SKV KV +D
Sbjct 3347 LPHVLPADSVVK---VGVSKPGVAHKALCTVTDIYLPMLGSYTSPP---TQSKVYKVNVD 3400
Query 324 YTEISFMLW 332
+ M+W
Sbjct 3401 HKACKLMVW 3409
>sp|B8J0P3|UPPP_DESDA Undecaprenyl-diphosphatase OS=Desulfovibrio
desulfuricans (strain ATCC 27774 / DSM 6949 / MB) OX=525146
GN=uppP PE=3 SV=1
Length=265
Score = 33.5 bits (75), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 26/107 (24%), Positives = 45/107 (42%), Gaps = 4/107 (4%)
Query 119 LTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNY 178
LT V+G + + +G LI G + G VG K A+ + V +G + Y
Sbjct 5 LTALILSIVEGLTEFLPVSSSGHLILAGDLLGF---VGEKAATFDVVIQLGAIMAVVVLY 61
Query 179 YKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERY 225
+K+ G+V+ P F R + + + L L + +I+ Y
Sbjct 62 WKRFWGLVRPQPYARFAGRRGIVLLM-LTSLPACILGLLLHAYIKEY 107
>sp|A5N7P1|TRPA_CLOK5 Tryptophan synthase alpha chain OS=Clostridium
kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680) OX=431943
GN=trpA PE=3 SV=1
Length=263
Score = 32.3 bits (72), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 18/48 (38%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query 161 SLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETY---FTQSRNLQEFKP 205
S NGVT +GE +KT Y ++ G +LP+ + S +EFKP
Sbjct 176 SKNGVTGVGEKIKTDIKEYMELVGSYTELPKALGFGISGSSMAREFKP 223
>sp|B9E152|TRPA_CLOK1 Tryptophan synthase alpha chain OS=Clostridium
kluyveri (strain NBRC 12016) OX=583346 GN=trpA PE=3 SV=1
Length=263
Score = 32.3 bits (72), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 18/48 (38%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query 161 SLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETY---FTQSRNLQEFKP 205
S NGVT +GE +KT Y ++ G +LP+ + S +EFKP
Sbjct 176 SKNGVTGVGEKIKTDIKEYMELVGSYTELPKALGFGISGSSMAREFKP 223
>sp|Q11CB2|GLK_CHESB Glucokinase OS=Chelativorans sp. (strain
BNC1) OX=266779 GN=glk PE=3 SV=1
Length=342
Score = 32.3 bits (72), Expect = 7.3, Method: Compositional matrix adjust.
Identities = 22/64 (34%), Positives = 35/64 (55%), Gaps = 5/64 (8%)
Query 92 APAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGL 151
+PA I+T G+ +IA ET+ L V + GRV G + L +R GV +T G + +
Sbjct 225 SPAEITTAGLAQADEIA---VETLN--LFVTYLGRVAGDLGLVFMSRGGVFLTGGIAQKI 279
Query 152 QPSV 155
P++
Sbjct 280 VPAL 283
>sp|Q1RIG1|RS15_RICBR Small ribosomal subunit protein uS15 OS=Rickettsia
bellii (strain RML369-C) OX=336407 GN=rpsO PE=3 SV=1
Length=91
Score = 30.4 bits (67), Expect = 7.5, Method: Composition-based stats.
Identities = 13/34 (38%), Positives = 20/34 (59%), Gaps = 0/34 (0%)
Query 275 VKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKS 308
+KNY I D TGSS C+++ +++ E KS
Sbjct 12 IKNYAINDNDTGSSAVQCAILTERINNLTEHFKS 45
>sp|A8GWV1|RS15_RICB8 Small ribosomal subunit protein uS15 OS=Rickettsia
bellii (strain OSU 85-389) OX=391896 GN=rpsO PE=3
SV=1
Length=91
Score = 30.4 bits (67), Expect = 7.5, Method: Composition-based stats.
Identities = 13/34 (38%), Positives = 20/34 (59%), Gaps = 0/34 (0%)
Query 275 VKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKS 308
+KNY I D TGSS C+++ +++ E KS
Sbjct 12 IKNYAINDNDTGSSAVQCAILTERINNLTEHFKS 45
>sp|A4QGU3|Y2449_CORGB Putative hydro-lyase cgR_2449 OS=Corynebacterium
glutamicum (strain R) OX=340322 GN=cgR_2449 PE=3 SV=1
Length=264
Score = 31.6 bits (70), Expect = 8.9, Method: Compositional matrix adjust.
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 5/54 (9%)
Query 45 NKTTLPVNVAFE--LWAKRNIKPVPEVKILN---NLGVDIAANTVIWDYKRDAP 93
N ++P ++A++ L+A+RN KP P +++LN G +N D + DAP
Sbjct 34 NLISMPQDLAYDFLLFAQRNPKPCPILEVLNAGETFGGIFGSNATEADIRTDAP 87
>sp|Q8NMM7|Y2544_CORGL Putative hydro-lyase Cgl2544/cg2803 OS=Corynebacterium
glutamicum (strain ATCC 13032 / DSM 20300 /
BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=Cgl2544
PE=3 SV=1
Length=264
Score = 31.6 bits (70), Expect = 9.3, Method: Compositional matrix adjust.
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 5/54 (9%)
Query 45 NKTTLPVNVAFE--LWAKRNIKPVPEVKILN---NLGVDIAANTVIWDYKRDAP 93
N ++P ++A++ L+A+RN KP P +++LN G +N D + DAP
Sbjct 34 NLISMPQDLAYDFLLFAQRNPKPCPILEVLNAGETFGGIFGSNATEADIRTDAP 87
Lambda K H a alpha
0.319 0.137 0.402 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 31483955226
Results from round 2
Query= YP_009725310.1 endoRNAse [Severe acute respiratory syndrome
coronavirus 2]
Length=346
Score E
Sequences producing significant alignments: (Bits) Value
Sequences used in model and found again:
sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute res... 509 1e-163
sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus... 508 4e-163
sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus... 489 1e-156
sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus... 488 4e-156
sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus... 482 4e-154
sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemi... 482 5e-154
sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute re... 471 2e-150
sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East res... 471 3e-150
sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus... 471 3e-150
sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus... 469 1e-149
sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus... 468 3e-149
sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavir... 466 2e-148
sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavir... 466 2e-148
sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavir... 465 4e-148
sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavi... 465 4e-148
sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavir... 465 5e-148
sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavir... 464 6e-148
sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavir... 464 7e-148
sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavi... 463 2e-147
sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavi... 463 2e-147
sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavir... 463 2e-147
sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavir... 459 6e-146
sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavi... 454 2e-144
sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavir... 454 4e-144
sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus... 451 2e-143
sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmi... 449 2e-142
sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavir... 442 6e-140
sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectiou... 385 3e-120
sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious... 385 3e-120
sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious... 375 1e-116
sp|P18457|R1AB_CVPFS Replicase polyprotein 1ab (Fragment) OS=Porc... 276 2e-87
sp|P12723|R1AB_IBVK Replicase polyprotein 1ab (Fragment) OS=Avian... 211 1e-62
sp|A6YQT5|RPOA_PRRSV Replicase polyprotein 1ab OS=Porcine reprodu... 153 9e-40
sp|P19811|RPOA_EAVBU Replicase polyprotein 1ab OS=Equine arteriti... 137 2e-34
sp|P0C6V8|R1AB_BRV1 Replicase polyprotein 1ab OS=Breda virus 1 OX... 134 2e-33
Sequences not found previously or not previously below threshold:
sp|Q8B912|RPOA_PRRSB Replicase polyprotein 1ab OS=Porcine reprodu... 151 5e-39
sp|Q9YN02|RPOA_PRRS1 Replicase polyprotein 1ab OS=Porcine reprodu... 144 1e-36
sp|Q9WJB2|RPOA_PRRSR Replicase polyprotein 1ab OS=Porcine reprodu... 143 3e-36
sp|P0C6V7|R1AB_BEV Replicase polyprotein 1ab OS=Berne virus OX=11... 122 3e-29
sp|Q68772|RPOA_SHFV Replicase polyprotein 1ab OS=Simian hemorrhag... 112 1e-25
sp|Q04561|RPOA_PRRSL Replicase polyprotein 1ab OS=Porcine reprodu... 110 4e-25
sp|A0MD28|RPOA_PRRSS Replicase polyprotein 1ab OS=Porcine reprodu... 108 1e-24
sp|Q06502|RPOA_LDVC Replicase polyprotein 1ab OS=Lactate dehydrog... 90.1 3e-18
sp|Q83017|RPOA_LDVP Replicase polyprotein 1ab OS=Lactate dehydrog... 84.7 2e-16
sp|A6QLQ8|ENDOU_BOVIN Uridylate-specific endoribonuclease OS=Bos ... 35.0 0.87
sp|Q9PTU6|ENDOU_PAROL Uridylate-specific endoribonuclease OS=Para... 34.6 1.4
sp|A8E627|ENDUD_XENLA Uridylate-specific endoribonuclease D OS=Xe... 33.8 1.8
sp|A8E624|ENDUC_XENLA Uridylate-specific endoribonuclease C OS=Xe... 33.5 3.0
sp|Q3V188|ENDOU_MOUSE Uridylate-specific endoribonuclease OS=Mus ... 33.1 3.8
sp|P47370|THIO_MYCGE Thioredoxin OS=Mycoplasma genitalium (strain... 31.2 4.1
sp|A1L237|ENDUA_DANRE Uridylate-specific endoribonuclease A OS=Da... 31.9 8.4
sp|P21128|ENDOU_HUMAN Uridylate-specific endoribonuclease OS=Homo... 31.9 9.6
sp|A2C1G5|PSB28_PROM1 Photosystem II reaction center Psb28 protei... 30.4 9.7
>sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus OX=694009 GN=rep PE=1 SV=1
Length=7073
Score = 509 bits (1312), Expect = 1e-163, Method: Composition-based stats.
Identities = 307/346 (89%), Positives = 331/346 (96%), Gaps = 0/346 (0%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENVA+NVVNKGHFDG GE PVSIINN VYTKVDG+DVE+FENKTTLPVNVAFELWAK
Sbjct 6430 SLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAK 6489
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
RNIKPVPE+KILNNLGVDIAANTVIWDYKR+APAH+STIGVC+MTDIAKKPTE+ C+ LT
Sbjct 6490 RNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLT 6549
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYK 180
V FDGRV+GQVDLFRNARNGVLITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+K
Sbjct 6550 VLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFK 6609
Query 181 KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF 240
KVDG++QQLPETYFTQSR+L++FKPRSQME DFLELAMDEFI+RYKLEGYAFEHIVYGDF
Sbjct 6610 KVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDF 6669
Query 241 SHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 300
SH QLGGLHL+IGLAKR ++SP +LEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD
Sbjct 6670 SHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 6729
Query 301 DFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DFVEIIKSQDLSV+SKVVKVTIDY EISFMLWCKDGHVETFYPKLQ
Sbjct 6730 DFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQ 6775
>sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus
279/2005 OX=389167 GN=rep PE=3 SV=1
Length=7079
Score = 508 bits (1308), Expect = 4e-163, Method: Composition-based stats.
Identities = 306/346 (88%), Positives = 330/346 (95%), Gaps = 0/346 (0%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENVA+NVVNKGHFDGQ GE PVSIINN VYTKVDG DVE+FENKTTLPVNVAFELWAK
Sbjct 6436 SLENVAYNVVNKGHFDGQIGEAPVSIINNAVYTKVDGNDVEIFENKTTLPVNVAFELWAK 6495
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
RNIKPVPE+KILNNLGVDIAANTVIWDYKR+APAH+STIGVC+MTDIAKKPTE+ C+ LT
Sbjct 6496 RNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLT 6555
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYK 180
V FDGRV+GQVDLFRNARNGVLITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+K
Sbjct 6556 VLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFK 6615
Query 181 KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF 240
KVDG++QQLPETYFTQSR+L++FKPRS+ME DFLELAMDEFI+RYKLEGYAFEHIVYGDF
Sbjct 6616 KVDGIIQQLPETYFTQSRDLEDFKPRSKMETDFLELAMDEFIQRYKLEGYAFEHIVYGDF 6675
Query 241 SHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 300
SH QLGGLHL+IGLAKR ++SP +LEDFIP DSTVKNYFITDAQTGSSKCVCSVIDLLLD
Sbjct 6676 SHGQLGGLHLMIGLAKRSQDSPLKLEDFIPTDSTVKNYFITDAQTGSSKCVCSVIDLLLD 6735
Query 301 DFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DFVEIIKSQDLSV+SKVVKVTIDY EISFMLWCKDGHVETFYPKLQ
Sbjct 6736 DFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQ 6781
>sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus
HKU3 OX=442736 GN=rep PE=3 SV=1
Length=7067
Score = 489 bits (1260), Expect = 1e-156, Method: Composition-based stats.
Identities = 305/346 (88%), Positives = 328/346 (95%), Gaps = 0/346 (0%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENVA+NVVNKGHFDGQ GE PVSIINN VYTKVDG+DVE+FENKTTLPVNVAFELWAK
Sbjct 6424 SLENVAYNVVNKGHFDGQSGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAK 6483
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
RNIKPVPE+KILNNLGVDIAAN VIWDYKR+APAH+STIGVC+MTDIAKKPTE+ C+ L
Sbjct 6484 RNIKPVPEIKILNNLGVDIAANNVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLI 6543
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYK 180
V FDGRV+GQVD FRNARNGVLITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+K
Sbjct 6544 VLFDGRVEGQVDFFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFK 6603
Query 181 KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF 240
KVDG++QQLPETYFTQSR+L++FKPRSQME DFLELAMDEFI+RYKLEGYAFEHIVYGDF
Sbjct 6604 KVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDF 6663
Query 241 SHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 300
SH QLGGLHL+IGLAKR ++S +LEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD
Sbjct 6664 SHGQLGGLHLMIGLAKRSQDSLLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 6723
Query 301 DFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DFVEIIKSQDLSVVSKVVKVTIDY EISFMLWCKDGHVETFYPKLQ
Sbjct 6724 DFVEIIKSQDLSVVSKVVKVTIDYAEISFMLWCKDGHVETFYPKLQ 6769
>sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus
Rp3/2004 OX=349344 GN=rep PE=3 SV=1
Length=7071
Score = 488 bits (1256), Expect = 4e-156, Method: Composition-based stats.
Identities = 306/346 (88%), Positives = 329/346 (95%), Gaps = 0/346 (0%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENVA+NVVNKGHFDGQ GE PVSIINN VYTKVDG DVE+FENKTTLPVNVAFELWAK
Sbjct 6428 SLENVAYNVVNKGHFDGQAGETPVSIINNAVYTKVDGFDVEIFENKTTLPVNVAFELWAK 6487
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
RNIK VPE+KILNNLGVDIAANTVIWD+KR+AP H+STIGVC+MTDIAKKPTE+ C+ LT
Sbjct 6488 RNIKSVPEIKILNNLGVDIAANTVIWDHKREAPVHMSTIGVCTMTDIAKKPTESACSSLT 6547
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYK 180
V FDGRV+GQVDLFRNARNGVLITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+K
Sbjct 6548 VLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFK 6607
Query 181 KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF 240
KVDG++QQLPETYFTQSR+L++FKPRSQME DFLELAMDEFI+RYKLEGYAFEHIVYGDF
Sbjct 6608 KVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDF 6667
Query 241 SHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 300
SH QLGGLHL+IGLAKR ++SP +LEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD
Sbjct 6668 SHGQLGGLHLMIGLAKRSRDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 6727
Query 301 DFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DFVEIIKSQDLSVVSKVVKVTIDY EISFMLWCKDGHVETFYPKLQ
Sbjct 6728 DFVEIIKSQDLSVVSKVVKVTIDYAEISFMLWCKDGHVETFYPKLQ 6773
>sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus
512/2005 OX=693999 GN=rep PE=3 SV=1
Length=6793
Score = 482 bits (1241), Expect = 4e-154, Method: Composition-based stats.
Identities = 156/347 (45%), Positives = 206/347 (59%), Gaps = 11/347 (3%)
Query 2 LENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKR 61
LEN+A+NVV KG F G +GE+PV+++N+ V + D +F N T+LP NVAFEL+AKR
Sbjct 6155 LENIAYNVVKKGSFVGVEGELPVAVVNDKVMVRDGVSDNVVFVNNTSLPTNVAFELYAKR 6214
Query 62 NIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTV 121
+ P + IL NLGV + V+WDY+ P T VC TD +
Sbjct 6215 KVGLTPPLTILKNLGVVCTSKCVLWDYEASRPLTTFTKDVCKYTDFD--------GDVCT 6266
Query 122 FFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNY-YK 180
FD V G + F +N VLI+ +VK L ++ LNGV + K Y Y
Sbjct 6267 LFDNSVPGAFERFTVTKNAVLISLTAVKKLT-AIKLTYGYLNGVPVFTHEDKPFTWYIYT 6325
Query 181 KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF 240
+ DG + P+ YFTQ R + +F+PRS ME DFL + M FI +Y LE Y FEH+V+GD
Sbjct 6326 RKDGAFVEYPDGYFTQGRVISDFQPRSNMEEDFLNMDMGLFISKYGLEDYGFEHVVFGDV 6385
Query 241 SHSQLGGLHLLIGLAKRFKESPFELEDFI-PMDSTVKNYFITDAQTGSSKCVCSVIDLLL 299
S + LGGLHLLI + K ++EDF+ DST+K+ +T SSK VC+ +DLLL
Sbjct 6386 SKTTLGGLHLLISQIRLSKIGVLKVEDFVSSSDSTLKSCTVTYVDNPSSKMVCTYVDLLL 6445
Query 300 DDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DDFV I+KS DLSVVSKV +V ID +MLWCKD V+TFYP+LQ
Sbjct 6446 DDFVNILKSVDLSVVSKVHEVVIDCKVWRWMLWCKDHKVQTFYPQLQ 6492
>sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=rep PE=1 SV=1
Length=6781
Score = 482 bits (1240), Expect = 5e-154, Method: Composition-based stats.
Identities = 153/347 (44%), Positives = 206/347 (59%), Gaps = 11/347 (3%)
Query 2 LENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKR 61
LEN+AFNV+ KG F G +GE+PV+++N+ V + VD +F NKT+LP NVAFEL+AKR
Sbjct 6143 LENIAFNVLKKGSFVGDEGELPVAVVNDKVLVRDGTVDTLVFTNKTSLPTNVAFELYAKR 6202
Query 62 NIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTV 121
+ P + IL NLGV + VIWDY+ + P T VC TD +
Sbjct 6203 KVGLTPPITILRNLGVVCTSKCVIWDYEAERPLTTFTKDVCKYTDFE--------GDVCT 6254
Query 122 FFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNY-YK 180
FD + G ++ F +N VL++ +VK L LNGV + K Y Y
Sbjct 6255 LFDNSIVGSLERFSMTQNAVLMSLTAVKKLTGI-KLTYGYLNGVPVNTHEDKPFTWYIYT 6313
Query 181 KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF 240
+ +G + P+ YFTQ R +F PRS ME DFL + M FI +Y LE Y FEH+VYGD
Sbjct 6314 RKNGKFEDYPDGYFTQGRTTADFSPRSDMEKDFLSMDMGLFINKYGLEDYGFEHVVYGDV 6373
Query 241 SHSQLGGLHLLIGLAKRFKESPFELEDFIPM-DSTVKNYFITDAQTGSSKCVCSVIDLLL 299
S + LGGLHLLI + ++++F+ DST+K+ +T A SSK VC+ +DLLL
Sbjct 6374 SKTTLGGLHLLISQVRLACMGVLKIDEFVSSNDSTLKSCTVTYADNPSSKMVCTYMDLLL 6433
Query 300 DDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DDFV I+KS DLSVVSKV +V +D +MLWCKD ++TFYP+LQ
Sbjct 6434 DDFVSILKSLDLSVVSKVHEVMVDCKMWRWMLWCKDHKLQTFYPQLQ 6480
>sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 GN=rep PE=1
SV=1
Length=7096
Score = 471 bits (1213), Expect = 2e-150, Method: Composition-based stats.
Identities = 346/346 (100%), Positives = 346/346 (100%), Gaps = 0/346 (0%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK
Sbjct 6453 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 6512
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT
Sbjct 6513 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 6572
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYK 180
VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYK
Sbjct 6573 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYK 6632
Query 181 KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF 240
KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF
Sbjct 6633 KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF 6692
Query 241 SHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 300
SHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD
Sbjct 6693 SHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 6752
Query 301 DFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ
Sbjct 6753 DFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 6798
>sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East
respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=rep PE=1 SV=1
Length=7078
Score = 471 bits (1212), Expect = 3e-150, Method: Composition-based stats.
Identities = 176/348 (51%), Positives = 226/348 (65%), Gaps = 9/348 (3%)
Query 2 LENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKR 61
LEN+AFN V +GHF G +GE+PV+++N+ ++TK D+ +FENKTTLP N+AFEL+AKR
Sbjct 6434 LENIAFNFVKQGHFIGVEGELPVAVVNDKIFTKSGVNDICMFENKTTLPTNIAFELYAKR 6493
Query 62 NIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTV 121
++ P+ K+L+NL DI V+WDY+R +TIGVC TDI IC
Sbjct 6494 AVRSHPDFKLLHNLQADICYKFVLWDYERSNIYGTATIGVCKYTDIDVNSALNIC----- 6548
Query 122 FFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQ---FNY 178
FD R +G ++ F + N + I++ +K VGP A NG + V Q F
Sbjct 6549 -FDIRDNGSLEKFMSTPNAIFISDRKIKKYPCMVGPDYAYFNGAIIRDSDVVKQPVKFYL 6607
Query 179 YKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYG 238
YKKV+ E +TQSR+ +F P S ME DFL D FI++Y LE YAFEH+VYG
Sbjct 6608 YKKVNNEFIDPTECIYTQSRSCSDFLPLSDMEKDFLSFDSDVFIKKYGLENYAFEHVVYG 6667
Query 239 DFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLL 298
DFSH+ LGGLHLLIGL K+ +E +E+ + ST+ NYFIT+ T + K VCSVIDL
Sbjct 6668 DFSHTTLGGLHLLIGLYKKQQEGHIIMEEMLKGSSTIHNYFITETNTAAFKAVCSVIDLK 6727
Query 299 LDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
LDDFV I+KSQDL VVSKVVKV ID T I FMLWCKDG V+TFYP+LQ
Sbjct 6728 LDDFVMILKSQDLGVVSKVVKVPIDLTMIEFMLWCKDGQVQTFYPRLQ 6775
>sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus
133/2005 OX=389230 GN=rep PE=3 SV=1
Length=7126
Score = 471 bits (1212), Expect = 3e-150, Method: Composition-based stats.
Identities = 175/347 (50%), Positives = 227/347 (65%), Gaps = 8/347 (2%)
Query 2 LENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKR 61
LEN+AFNV+ +GHF G GE+PV+++N+ ++TK DV +F+N+T LP NVAFEL+AKR
Sbjct 6484 LENIAFNVIKQGHFTGVDGELPVAVVNDKIFTKNGTDDVCIFKNETALPTNVAFELYAKR 6543
Query 62 NIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTV 121
++ P++ +L NL VD+ N V+WDY R+ +TIGVC TDI P +C
Sbjct 6544 AVRSHPDLNLLRNLEVDVCYNFVLWDYDRNNIYGTTTIGVCKYTDIDVNPNLNMC----- 6598
Query 122 FFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGEAVKTQFNYY 179
FD R G ++ F + NGVLI++ +K +GPK A NG L I F Y
Sbjct 6599 -FDIRDKGSLERFMSMPNGVLISDRKIKNYPCIIGPKHAYFNGAILRNIDAKQPITFYLY 6657
Query 180 KKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGD 239
KKV+ +T++T R + +F + ME DFL L D FI++Y LE YAFEH+VYGD
Sbjct 6658 KKVNNEFVSFSDTFYTCGRTVNDFTALTPMEEDFLVLDSDVFIKKYSLEDYAFEHVVYGD 6717
Query 240 FSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLL 299
FSH+ LGGLHLLIGL K+ ++ +E+ + +TV NYFITD+ T S K VCSVIDL L
Sbjct 6718 FSHTTLGGLHLLIGLYKKMRDGHILMEEMLKDRATVHNYFITDSNTASYKAVCSVIDLRL 6777
Query 300 DDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DDFV IIK DL VVSKVVKV ID T I FMLWCKDG V+TFYP+LQ
Sbjct 6778 DDFVNIIKEMDLDVVSKVVKVPIDLTMIEFMLWCKDGKVQTFYPRLQ 6824
>sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus
HKU5 OX=694008 GN=rep PE=3 SV=1
Length=7182
Score = 469 bits (1208), Expect = 1e-149, Method: Composition-based stats.
Identities = 176/356 (49%), Positives = 230/356 (65%), Gaps = 17/356 (5%)
Query 2 LENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKR 61
LEN+A+NV+ +GHF G +GE+PV+++N+ +YTK D DV +FENKTTLP N+AFEL+AKR
Sbjct 6525 LENIAYNVIKQGHFTGVEGELPVAVVNDKIYTKSDVNDVCIFENKTTLPTNIAFELYAKR 6584
Query 62 NIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTV 121
++ P+ +L NL VD+ V+WDY+R +TIGVC TDI IC
Sbjct 6585 AVRSHPDFNLLRNLEVDVCYKFVLWDYERSNIYGSATIGVCKYTDIDVNSALNIC----- 6639
Query 122 FFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGE----------- 170
FD R +G ++ F + NG+LI++ VK V A NG +
Sbjct 6640 -FDIRDNGSLERFMSLPNGILISDRKVKNYPCIVSSNYAYFNGTLIRDNTGNSQSSDGEV 6698
Query 171 AVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGY 230
F YKKV+ Q +TY+T R + +F P S+ME DFL L D FI++YKLE Y
Sbjct 6699 KQPVTFYIYKKVNNEFVQFTDTYYTLGRTVSDFTPVSEMEKDFLALDSDVFIKKYKLEAY 6758
Query 231 AFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKC 290
AFEH+VYGDFS + LGGLHLLIGL K+ +E +E+ + +TV NYF+T++ T S K
Sbjct 6759 AFEHVVYGDFSRTTLGGLHLLIGLYKKHQEGHIIMEEMLKERATVHNYFVTESNTASFKA 6818
Query 291 VCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
VCSVIDL LDDFV+IIK+ DLSVVSKVVK+ ID T I FMLWCKDG V+TFYP+LQ
Sbjct 6819 VCSVIDLKLDDFVDIIKAMDLSVVSKVVKIPIDLTMIEFMLWCKDGQVQTFYPRLQ 6874
>sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus
HKU4 OX=694007 GN=rep PE=1 SV=1
Length=7119
Score = 468 bits (1204), Expect = 3e-149, Method: Composition-based stats.
Identities = 175/347 (50%), Positives = 226/347 (65%), Gaps = 8/347 (2%)
Query 2 LENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKR 61
LEN+AFNV+ +GHF G GE+PV+++N+ ++TK DV +F+N+T LP NVAFEL+AKR
Sbjct 6477 LENIAFNVIKQGHFTGVDGELPVAVVNDKIFTKNGTDDVCIFKNETALPTNVAFELYAKR 6536
Query 62 NIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTV 121
++ P++ +L NL VD+ N V+WDY R+ +TIGVC TDI P +C
Sbjct 6537 AVRSHPDLNLLRNLEVDVCYNFVLWDYDRNNIYGTTTIGVCKYTDIDVNPNLNMC----- 6591
Query 122 FFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGEAVKTQFNYY 179
FD R G ++ F + NGVLI++ +K GPK A NG L I F Y
Sbjct 6592 -FDIRDKGSLERFMSMPNGVLISDRKIKNYPCISGPKHAYFNGAILRNIDAKQPVIFYLY 6650
Query 180 KKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGD 239
KKV+ +T++T R + +F + ME DFL L D FI++Y LE YAFEH+VYGD
Sbjct 6651 KKVNNEFVSFSDTFYTCGRTVGDFTVLTPMEEDFLVLDSDVFIKKYGLEDYAFEHVVYGD 6710
Query 240 FSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLL 299
FSH+ LGGLHLLIGL K+ +E +E+ + +TV NYFITD+ T S K VCSVIDL L
Sbjct 6711 FSHTTLGGLHLLIGLYKKMREGHILMEEMLKDRATVHNYFITDSNTASYKAVCSVIDLRL 6770
Query 300 DDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DDFV IIK DL VVSKVVKV ID T I FMLWC+DG V+TFYP+LQ
Sbjct 6771 DDFVTIIKEMDLDVVSKVVKVPIDLTMIEFMLWCRDGKVQTFYPRLQ 6817
>sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavirus
(strain 2) OX=76344 GN=rep PE=3 SV=1
Length=7124
Score = 466 bits (1198), Expect = 2e-148, Method: Composition-based stats.
Identities = 167/380 (44%), Positives = 229/380 (60%), Gaps = 40/380 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+VN GHFDG+ GE+P ++I V K+ DV +F+N T P NVA EL+AK
Sbjct 6452 SLENVVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVFKNNTPFPTNVAVELFAK 6511
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+P PE+K+ NL +D+ + V+WDY +D+ ST VC TD+ L
Sbjct 6512 RSIRPHPELKLFRNLNIDVCWSHVLWDYAKDSVFCSSTYKVCKYTDLQ------CIESLN 6565
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLI---GEAVKTQFN 177
V FDGR +G ++ F+ R+GV I +K L GP++A LNGV + V+ F
Sbjct 6566 VLFDGRDNGALEAFKKCRDGVYINTTKIKSLSMIKGPQRADLNGVVVEKVGDSDVEFWFA 6625
Query 178 YYKKVDGVVQQLP-------------------------------ETYFTQSRNLQEFKPR 206
+ D V+ T FTQSR L F PR
Sbjct 6626 MRRDGDDVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEALARGTIFTQSRFLSSFAPR 6685
Query 207 SQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELE 266
S+ME DF++L D FI +Y L+ YAFEH+VYG F+ +GGLHLLIGLA+R ++S ++
Sbjct 6686 SEMEKDFMDLDEDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRQQKSNLVIQ 6745
Query 267 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTE 326
+F+P DS++ +YFITD +GSSK VC+VIDLLLDDFV+I+KS +L+ VSKVV V +D+ +
Sbjct 6746 EFVPYDSSIHSYFITDENSGSSKSVCTVIDLLLDDFVDIVKSLNLNCVSKVVNVNVDFKD 6805
Query 327 ISFMLWCKDGHVETFYPKLQ 346
FMLWC + V TFYP+LQ
Sbjct 6806 FQFMLWCNEEKVMTFYPRLQ 6825
>sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=rep PE=3 SV=1
Length=7152
Score = 466 bits (1198), Expect = 2e-148, Method: Composition-based stats.
Identities = 171/380 (45%), Positives = 236/380 (62%), Gaps = 40/380 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+VN GH+DG+ GE+P +I+N+ V K++ VD +F+N T+LP N+A EL+ K
Sbjct 6480 SLENVIYNLVNAGHYDGRIGELPCAIMNDKVVVKINNVDTVIFKNNTSLPTNIAVELFTK 6539
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+ PE+KIL NL +DI V+WDY +D+ ST GVC TD+ L
Sbjct 6540 RSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCSSTYGVCKYTDL------NFIENLN 6593
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGE-AVKTQFN 177
V FDGR +G ++ FR ARNGV I+ G + L GP++A LNGV + +GE V+ F
Sbjct 6594 VLFDGRDNGALEAFRKARNGVFISTGKLSSLSMIKGPQRADLNGVIVDKVGELNVEFWFA 6653
Query 178 YYKKVDGVVQQLPE-------------------------------TYFTQSRNLQEFKPR 206
K D V+ + T FTQSR L F+PR
Sbjct 6654 MRKDGDDVIFSRADSLSPSHYWSPQGNLGGNCAGNASGNDALARFTIFTQSRVLSTFEPR 6713
Query 207 SQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELE 266
S +E DF+++ FI +Y LE YAF+HIVYG F++ +GGLHLLIGL +R K+S ++
Sbjct 6714 SDLERDFIDMEDSLFIAKYGLEDYAFDHIVYGSFNYKVIGGLHLLIGLFRRLKKSNLVIQ 6773
Query 267 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTE 326
+F+ DS++ +YFITD + GSSK VC+VIDLLLDDFV I+KS +L+ VSKVV + +D+ +
Sbjct 6774 EFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDDFVVIVKSLNLNCVSKVVNINVDFKD 6833
Query 327 ISFMLWCKDGHVETFYPKLQ 346
FMLWC D + TFYPK+Q
Sbjct 6834 FQFMLWCNDNKIMTFYPKMQ 6853
>sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=rep PE=3 SV=1
Length=7132
Score = 465 bits (1197), Expect = 4e-148, Method: Composition-based stats.
Identities = 170/380 (45%), Positives = 234/380 (62%), Gaps = 40/380 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+VN GH+DG+ GE+P +I+N+ V K++ VD +F+N T+ P N+A EL+ K
Sbjct 6460 SLENVIYNLVNVGHYDGRTGELPCAIMNDKVVVKINNVDTVIFKNNTSFPTNIAVELFTK 6519
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+ PE+KIL NL +DI V+WDY +D+ ST GVC TD+ L
Sbjct 6520 RSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCSSTYGVCKYTDLK------FIENLN 6573
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGE-AVKTQFN 177
+ FDGR G ++ FR ARNGV I+ + L GP++A LNGV + +GE V+ F
Sbjct 6574 ILFDGRDTGALEAFRKARNGVFISTEKLSRLSMIKGPQRADLNGVIVDKVGELKVEFWFA 6633
Query 178 YYKKVDGVVQQLPE-------------------------------TYFTQSRNLQEFKPR 206
K D V+ + T FTQSR L F+PR
Sbjct 6634 MRKDGDDVIFSRTDSLCSSHYWSPQGNLGGNCAGNVIGNDALTRFTIFTQSRVLSSFEPR 6693
Query 207 SQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELE 266
S +E DF+++ + FI +Y LE YAF+HIVYG F+H +GGLHLLIGL +R K+S ++
Sbjct 6694 SDLERDFIDMDDNLFIAKYGLEDYAFDHIVYGSFNHKVIGGLHLLIGLFRRLKKSNLLIQ 6753
Query 267 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTE 326
+F+ DS++ +YFITD + GSSK VC+VIDLLLDDFV I+KS +LS VSKVV + +D+ +
Sbjct 6754 EFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDDFVSIVKSLNLSCVSKVVNINVDFKD 6813
Query 327 ISFMLWCKDGHVETFYPKLQ 346
FMLWC D + TFYPK+Q
Sbjct 6814 FQFMLWCNDNKIMTFYPKMQ 6833
>sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavirus
(strain A59) OX=11142 GN=rep PE=1 SV=1
Length=7176
Score = 465 bits (1197), Expect = 4e-148, Method: Composition-based stats.
Identities = 168/380 (44%), Positives = 227/380 (60%), Gaps = 40/380 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+VN GHFDG+ GE+P ++I V K+ DV +F+N T P NVA EL+AK
Sbjct 6504 SLENVVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVFKNNTPFPTNVAVELFAK 6563
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+P PE+K+ NL +D+ + V+WDY +D+ ST VC TD+ L
Sbjct 6564 RSIRPHPELKLFRNLNIDVCWSHVLWDYAKDSVFCSSTYKVCKYTDLQ------CIESLN 6617
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLI---GEAVKTQFN 177
V FDGR +G ++ F+ RNGV I +K L GP++A LNGV + V+ F
Sbjct 6618 VLFDGRDNGALEAFKKCRNGVYINTTKIKSLSMIKGPQRADLNGVVVEKVGDSDVEFWFA 6677
Query 178 YYKKVDGVVQQLP-------------------------------ETYFTQSRNLQEFKPR 206
K D V+ T FTQSR L F PR
Sbjct 6678 VRKDGDDVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEALARGTIFTQSRLLSSFTPR 6737
Query 207 SQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELE 266
S+ME DF++L D FI +Y L+ YAFEH+VYG F+ +GGLHLLIGLA+R ++S ++
Sbjct 6738 SEMEKDFMDLDDDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRQQKSNLVIQ 6797
Query 267 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTE 326
+F+ DS++ +YFITD +GSSK VC+VIDLLLDDFV+I+KS +L VSKVV V +D+ +
Sbjct 6798 EFVTYDSSIHSYFITDENSGSSKSVCTVIDLLLDDFVDIVKSLNLKCVSKVVNVNVDFKD 6857
Query 327 ISFMLWCKDGHVETFYPKLQ 346
FMLWC + V TFYP+LQ
Sbjct 6858 FQFMLWCNEEKVMTFYPRLQ 6877
>sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavirus
NL63 OX=277944 GN=rep PE=1 SV=1
Length=6729
Score = 465 bits (1196), Expect = 5e-148, Method: Composition-based stats.
Identities = 152/353 (43%), Positives = 202/353 (57%), Gaps = 16/353 (5%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLEN+AFNVV KG F G GE+PV+++N+ V+ + VD +F NKTTLP NVAFEL+AK
Sbjct 6086 SLENIAFNVVKKGCFTGVDGELPVAVVNDKVFVRYGDVDNLVFTNKTTLPTNVAFELFAK 6145
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R + P + IL NLGV V+WDY+ + P T VC TD +
Sbjct 6146 RKMGLTPPLSILKNLGVVATYKFVLWDYEAERPFTSYTKSVCKYTDFN--------EDVC 6197
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL------IGEAVKT 174
V FD + G + F N VL + +K L P LNG+ + G
Sbjct 6198 VCFDNSIQGSYERFTLTTNAVLFSTVVIKNLTPI-KLNFGMLNGMPVSSIKGDKGVEKLV 6256
Query 175 QFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEH 234
+ Y + +G Q + ++TQ RNL +F PRS ME DFL + M FI +Y LE + FEH
Sbjct 6257 NWYIYVRKNGQFQDHYDGFYTQGRNLSDFTPRSDMEYDFLNMDMGVFINKYGLEDFNFEH 6316
Query 235 IVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIP-MDSTVKNYFITDAQTGSSKCVCS 293
+VYGD S + LGGLHLLI + K + +DF+ D+T++ +T SSK VC+
Sbjct 6317 VVYGDVSKTTLGGLHLLISQFRLSKMGVLKADDFVTASDTTLRCCTVTYLNELSSKVVCT 6376
Query 294 VIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
+DLLLDDFV I+KS DL V+SKV +V ID +MLWCKD H+ TFYP+LQ
Sbjct 6377 YMDLLLDDFVTILKSLDLGVISKVHEVIIDNKPYRWMLWCKDNHLSTFYPQLQ 6429
>sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=rep PE=3 SV=1
Length=7182
Score = 464 bits (1195), Expect = 6e-148, Method: Composition-based stats.
Identities = 170/380 (45%), Positives = 234/380 (62%), Gaps = 40/380 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+VN GH+DG+ GE+P +I+N+ V K++ VD +F+N T+ P N+A EL+ K
Sbjct 6510 SLENVIYNLVNVGHYDGRTGELPCAIMNDKVVVKINNVDTVIFKNNTSFPTNIAVELFTK 6569
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+ PE+KIL NL +DI V+WDY +D+ ST GVC TD+ L
Sbjct 6570 RSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCSSTYGVCKYTDLK------FIENLN 6623
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL--IGE-AVKTQFN 177
+ FDGR G ++ FR ARNGV I+ + L GP++A LNGV + +GE V+ F
Sbjct 6624 ILFDGRDTGALEAFRKARNGVFISTEKLSRLSMIKGPQRADLNGVIVDKVGELKVEFWFA 6683
Query 178 YYKKVDGVVQQLPE-------------------------------TYFTQSRNLQEFKPR 206
K D V+ + T FTQSR L F+PR
Sbjct 6684 MRKDGDDVIFSRTDSLCSSHYWSPQGNLGGNCAGNVIGNDALTRFTIFTQSRVLSSFEPR 6743
Query 207 SQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELE 266
S +E DF+++ + FI +Y LE YAF+HIVYG F+H +GGLHLLIGL +R K+S ++
Sbjct 6744 SDLERDFIDMDDNLFIAKYGLEDYAFDHIVYGSFNHKVIGGLHLLIGLFRRKKKSNLLIQ 6803
Query 267 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTE 326
+F+ DS++ +YFITD + GSSK VC+VIDLLLDDFV I+KS +LS VSKVV + +D+ +
Sbjct 6804 EFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDDFVSIVKSLNLSCVSKVVNINVDFKD 6863
Query 327 ISFMLWCKDGHVETFYPKLQ 346
FMLWC D + TFYPK+Q
Sbjct 6864 FQFMLWCNDNKIMTFYPKMQ 6883
>sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=rep PE=3 SV=1
Length=7059
Score = 464 bits (1194), Expect = 7e-148, Method: Composition-based stats.
Identities = 163/380 (43%), Positives = 224/380 (59%), Gaps = 40/380 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+V GH+ GQ GE+P +IIN+ V K+D DV +F N TT P NVA EL+AK
Sbjct 6422 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK 6481
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+ PE+K+ NL +D+ VIWDY R++ +T GVC TD+ + L
Sbjct 6482 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLK------LIDKLN 6535
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL-IGEAVKTQFNYY 179
V FDGR +G ++ F+ + NGV I+ VK L GP +A LNGV + F +
Sbjct 6536 VLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFA 6595
Query 180 KKVDGVVQQLPE---------------------------------TYFTQSRNLQEFKPR 206
+ +G + T FTQSR + F R
Sbjct 6596 VRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNEPGNVGGNDALATSTIFTQSRVISSFTCR 6655
Query 207 SQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELE 266
+ ME DF+ L D FI++Y LE YAFEHIVYG+F+ +GGLHLLIGL +R + S ++
Sbjct 6656 TDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQ 6715
Query 267 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTE 326
+F+ DS++ +YFITD ++G SK VC+VID+LLDDFV ++KS +L+ VSKVV V +D+ +
Sbjct 6716 EFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKD 6775
Query 327 ISFMLWCKDGHVETFYPKLQ 346
FMLWC D V TFYP+LQ
Sbjct 6776 FQFMLWCNDEKVMTFYPRLQ 6795
>sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=rep PE=3 SV=1
Length=7094
Score = 463 bits (1192), Expect = 2e-147, Method: Composition-based stats.
Identities = 163/380 (43%), Positives = 223/380 (59%), Gaps = 40/380 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+V GH+ GQ GE+P +IIN+ V K+D DV +F N TT P NVA EL+AK
Sbjct 6422 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK 6481
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+ PE+K+ NL +D+ VIWDY R++ +T GVC TD+ L
Sbjct 6482 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLK------FIDKLN 6535
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL-IGEAVKTQFNYY 179
V FDGR +G ++ F+ + NGV I+ VK L GP +A LNGV + F +
Sbjct 6536 VLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFA 6595
Query 180 KKVDGVVQQLPE---------------------------------TYFTQSRNLQEFKPR 206
+ +G + T FTQSR + F R
Sbjct 6596 VRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNEPGNVGGNDALATSTIFTQSRVISSFTCR 6655
Query 207 SQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELE 266
+ ME DF+ L D FI++Y LE YAFEHIVYG+F+ +GGLHLLIGL +R + S ++
Sbjct 6656 TDMEKDFIALDQDLFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQ 6715
Query 267 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTE 326
+F+ DS++ +YFITD ++G SK VC+VID+LLDDFV ++KS +L+ VSKVV V +D+ +
Sbjct 6716 EFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKD 6775
Query 327 ISFMLWCKDGHVETFYPKLQ 346
FMLWC D V TFYP+LQ
Sbjct 6776 FQFMLWCNDEKVMTFYPRLQ 6795
>sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=rep PE=3 SV=1
Length=7094
Score = 463 bits (1192), Expect = 2e-147, Method: Composition-based stats.
Identities = 163/380 (43%), Positives = 223/380 (59%), Gaps = 40/380 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+V GH+ GQ GE+P +IIN+ V K+D DV +F N TT P NVA EL+AK
Sbjct 6422 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK 6481
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+ PE+K+ NL +D+ VIWDY R++ +T GVC TD+ L
Sbjct 6482 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLK------FIDKLN 6535
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL-IGEAVKTQFNYY 179
V FDGR +G ++ F+ + NGV I+ VK L GP +A LNGV + F +
Sbjct 6536 VLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKGPPRAELNGVVVDKVGDTDCVFYFA 6595
Query 180 KKVDGVVQQLPE---------------------------------TYFTQSRNLQEFKPR 206
+ +G + T FTQSR + F R
Sbjct 6596 VRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNEPGNVGGNDALATSTIFTQSRVISSFTCR 6655
Query 207 SQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELE 266
+ ME DF+ L D FI++Y LE YAFEHIVYG+F+ +GGLHLLIGL +R + S ++
Sbjct 6656 TDMEKDFIALDQDLFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQ 6715
Query 267 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTE 326
+F+ DS++ +YFITD ++G SK VC+VID+LLDDFV ++KS +L+ VSKVV V +D+ +
Sbjct 6716 EFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKD 6775
Query 327 ISFMLWCKDGHVETFYPKLQ 346
FMLWC D V TFYP+LQ
Sbjct 6776 FQFMLWCNDEKVMTFYPRLQ 6795
>sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavirus
OC43 OX=31631 GN=rep PE=1 SV=1
Length=7095
Score = 463 bits (1191), Expect = 2e-147, Method: Composition-based stats.
Identities = 163/381 (43%), Positives = 223/381 (59%), Gaps = 41/381 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+V GH+ GQ GE+P +IIN+ V TK+D DV +F N TT P NVA EL+AK
Sbjct 6422 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKIDKEDVVIFINNTTYPTNVAVELFAK 6481
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+++ PE+K+ NL +D+ VIWDY R++ +T GVC TD+ L
Sbjct 6482 RSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLK------FIDKLN 6535
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL-IGEAVKTQFNYY 179
V FDGR +G + F+ + NGV I+ VK L GP +A LNGV + F +
Sbjct 6536 VLFDGRDNGAFEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFA 6595
Query 180 KKVDGVVQQLPE----------------------------------TYFTQSRNLQEFKP 205
+ +G + T FTQSR + F
Sbjct 6596 VRKEGQDVIFSQFDSLGVSSNQSPQGNLGSNGKPGNVGGNDALSISTIFTQSRVISSFTC 6655
Query 206 RSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFEL 265
R+ ME DF+ L D FI++Y LE YAFEHIVYG+F+ +GGLHLLIGL +R + S +
Sbjct 6656 RTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVV 6715
Query 266 EDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYT 325
++F+ DS++ +YFITD ++G SK VC+VID+LLDDFV ++KS +L+ VSKVV V +D+
Sbjct 6716 QEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVTLVKSLNLNCVSKVVNVNVDFK 6775
Query 326 EISFMLWCKDGHVETFYPKLQ 346
+ FMLWC D V TFYP+LQ
Sbjct 6776 DFQFMLWCNDEKVMTFYPRLQ 6796
>sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=rep PE=3 SV=1
Length=7094
Score = 459 bits (1180), Expect = 6e-146, Method: Composition-based stats.
Identities = 162/380 (43%), Positives = 222/380 (58%), Gaps = 40/380 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+V GH+ GQ GE+P +IIN+ V K+D DV +F N TT P NVA EL+AK
Sbjct 6422 SLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTNVAVELFAK 6481
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+ PE+K+ NL +D+ VIWDY R++ +T GVC TD+ L
Sbjct 6482 RSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDLK------FIDKLN 6535
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTL-IGEAVKTQFNYY 179
V FDGR +G ++ F+ + NGV I+ VK L GP +A LNGV + F +
Sbjct 6536 VLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGDTDCVFYFA 6595
Query 180 KKVDGVVQQLPE---------------------------------TYFTQSRNLQEFKPR 206
+ +G + T FTQSR + F R
Sbjct 6596 VRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNEPGNVGGNDALATSTIFTQSRVISSFTCR 6655
Query 207 SQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELE 266
+ ME DF+ L D FI++Y LE YAFEHIVYG+F+ +GGLHLLIGL +R + S ++
Sbjct 6656 TDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQQTSNLVIQ 6715
Query 267 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTE 326
+F+ DS++ +YFITD ++G SK VC+VID+LLDDFV ++KS +L+ VSKVV V +D+ +
Sbjct 6716 EFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVVNVNVDFKD 6775
Query 327 ISFMLWCKDGHVETFYPKLQ 346
FMLWC D V TFY +LQ
Sbjct 6776 FQFMLWCNDEKVMTFYLRLQ 6795
>sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavirus
(strain JHM) OX=11144 GN=rep PE=1 SV=1
Length=7180
Score = 454 bits (1168), Expect = 2e-144, Method: Composition-based stats.
Identities = 165/380 (43%), Positives = 226/380 (59%), Gaps = 40/380 (11%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENV +N+VN GHFDG+ GE+P ++I V K+ DV +F+N T P NVA EL+A+
Sbjct 6508 SLENVVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVFKNNTPFPTNVAVELFAE 6567
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R+I+P PE+K+ + + + N V+WDY +D+ ST VC TD+ L
Sbjct 6568 RSIRPHPELKLFRSSNIHVCWNHVLWDYAKDSVFCSSTYKVCKYTDLQ------CIESLN 6621
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLI---GEAVKTQFN 177
V FDGR +G ++ F+ RNGV I +K L GP++A LNGV + V+ F
Sbjct 6622 VLFDGRDNGALEAFKKCRNGVYINTTKIKSLSMIKGPQRADLNGVVVEKVGDSDVEFWFA 6681
Query 178 YYKKVDGVVQQLP-------------------------------ETYFTQSRNLQEFKPR 206
+ D V+ T FTQSR L F PR
Sbjct 6682 MRRDGDDVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEALARGTIFTQSRFLSSFSPR 6741
Query 207 SQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELE 266
S+ME DF++L D FI +Y L+ YAFEH+VYG F+ +GGLHLLIGLA+R K+S ++
Sbjct 6742 SEMEKDFMDLDEDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRPKKSNLVIQ 6801
Query 267 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTE 326
+F+P DS++ +YFITD +GSS+ VC+VIDLLLDDFV+I+KS +L VSKVV V +D+ +
Sbjct 6802 EFVPYDSSIHSYFITDENSGSSESVCTVIDLLLDDFVDIVKSLNLKCVSKVVNVNVDFKD 6861
Query 327 ISFMLWCKDGHVETFYPKLQ 346
FMLWC + V TFYP+LQ
Sbjct 6862 FQFMLWCNEEKVMTFYPRLQ 6881
>sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavirus
229E OX=11137 GN=rep PE=1 SV=1
Length=6758
Score = 454 bits (1167), Expect = 4e-144, Method: Composition-based stats.
Identities = 149/355 (42%), Positives = 201/355 (57%), Gaps = 18/355 (5%)
Query 2 LENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKR 61
LEN+AFNVVNKG F G GE+PV+I + V+ + D +F NKT+LP N+AFEL+AKR
Sbjct 6112 LENIAFNVVNKGSFVGADGELPVAISGDKVFVRDGNTDNLVFVNKTSLPTNIAFELFAKR 6171
Query 62 NIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTV 121
+ P + IL NLGV V+WDY+ + P T VC TD A +
Sbjct 6172 KVGLTPPLSILKNLGVVATYKFVLWDYEAERPLTSFTKSVCGYTDFA--------EDVCT 6223
Query 122 FFDGRVDGQVDLFRNARNGVLITEGSVKGLQ---PSVGPKQASLNGVTLI------GEAV 172
+D + G + F + N VL + +VK P++ LNG + G
Sbjct 6224 CYDNSIQGSYERFTLSTNAVLFSATAVKTGGKSLPAIKLNFGMLNGNAIATVKSEDGNIK 6283
Query 173 KTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAF 232
+ Y + DG + ++TQ RNLQ+F PRS ME DFL + + FI++Y LE + F
Sbjct 6284 NINWFVYVRKDGKPVDHYDGFYTQGRNLQDFLPRSTMEEDFLNMDIGVFIQKYGLEDFNF 6343
Query 233 EHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFI-PMDSTVKNYFITDAQTGSSKCV 291
EH+VYGD S + LGGLHLLI + K + E+F+ D T+K +T SSK V
Sbjct 6344 EHVVYGDVSKTTLGGLHLLISQVRLSKMGILKAEEFVAASDITLKCCTVTYLNDPSSKTV 6403
Query 292 CSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
C+ +DLLLDDFV ++KS DL+VVSKV +V ID +MLWCKD V TFYP+LQ
Sbjct 6404 CTYMDLLLDDFVSVLKSLDLTVVSKVHEVIIDNKPWRWMLWCKDNAVATFYPQLQ 6458
>sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus
HKU9 OX=694006 GN=rep PE=1 SV=1
Length=6930
Score = 451 bits (1161), Expect = 2e-143, Method: Composition-based stats.
Identities = 161/346 (47%), Positives = 217/346 (63%), Gaps = 9/346 (3%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENVA+NV+ GHF GE+PV+I+N+ +Y K DG D LF N T LP NVAFELWAK
Sbjct 6297 SLENVAYNVLKSGHFTAVAGELPVAILNDRLYIKEDGADKLLFTNNTCLPTNVAFELWAK 6356
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R++ VPEVK+L NLGV N VIWDY+ +AP +T+G+C+ TD+ K +
Sbjct 6357 RSVNVVPEVKLLRNLGVTCTYNLVIWDYESNAPLVPNTVGICTYTDLTKLDDQ------V 6410
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYK 180
V DGR F +N + + K + + GP AS+NGV + T F Y
Sbjct 6411 VLVDGRQLDAYSKFCQLKNAIYFSPSKPKCV-CTRGPTHASINGVVVEAPDRGTAFWYAM 6469
Query 181 KVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDF 240
+ DG Q + YFTQSR + +F+PR+Q+EIDFL+L F+++Y L EHIVYG F
Sbjct 6470 RKDGAFVQPTDGYFTQSRTVDDFQPRTQLEIDFLDLEQSCFLDKYDLHDLGLEHIVYGQF 6529
Query 241 SHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 300
+ +GGLHLLIG +R + + +E + D TV +Y + D T SSK VCSV+D++LD
Sbjct 6530 DGT-IGGLHLLIGAVRRKRTAHLVMETVLGTD-TVTSYAVIDQPTASSKQVCSVVDIILD 6587
Query 301 DFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DF+ +IK+QD SVVSKVV+ +D+ FMLWCK G + TFYP+LQ
Sbjct 6588 DFIALIKAQDRSVVSKVVQCCLDFKVFRFMLWCKGGKISTFYPQLQ 6633
>sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=rep PE=1 SV=1
Length=6684
Score = 449 bits (1155), Expect = 2e-142, Method: Composition-based stats.
Identities = 149/348 (43%), Positives = 211/348 (61%), Gaps = 11/348 (3%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENVAFNVV KG F G +G++P ++I + + + D +F NKT+LP NVAFEL+AK
Sbjct 6046 SLENVAFNVVKKGAFTGLKGDLPTAVIADKIMVRDGPTDKCIFTNKTSLPTNVAFELYAK 6105
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R + P + IL NLGV V+WDY+ + P T VCS TD+ + +
Sbjct 6106 RKLGLTPPLTILRNLGVVATYKFVLWDYEAERPFSNFTKQVCSYTDLDSE--------VV 6157
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNY-Y 179
FD + G + F R+ VLI+ +VKGL ++ + LN + + K Y Y
Sbjct 6158 TCFDNSIAGSFERFTTTRDAVLISNNAVKGLS-AIKLQYGLLNDLPVSTVGNKPVTWYIY 6216
Query 180 KKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGD 239
+ +G + ++Y+TQ R + FKPRS ME DFL + FI++Y LE Y FEH+V+GD
Sbjct 6217 VRKNGEYVEQIDSYYTQGRTFETFKPRSTMEEDFLSMDTTLFIQKYGLEDYGFEHVVFGD 6276
Query 240 FSHSQLGGLHLLIGLAKRFKESPFELEDFI-PMDSTVKNYFITDAQTGSSKCVCSVIDLL 298
S + +GG+HLLI + K F +++F+ DST+K+ IT A SSK VC+ +D+L
Sbjct 6277 VSKTTIGGMHLLISQVRLAKMGLFSVQEFMNNSDSTLKSCCITYADDPSSKNVCTYMDIL 6336
Query 299 LDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
LDDFV IIKS DL+VVSKVV V +D +MLWC++ H++TFYP+LQ
Sbjct 6337 LDDFVTIIKSLDLNVVSKVVDVIVDCKAWRWMLWCENSHIKTFYPQLQ 6384
>sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavirus
(strain FIPV WSU-79/1146) OX=33734 GN=rep PE=1 SV=2
Length=6709
Score = 442 bits (1136), Expect = 6e-140, Method: Composition-based stats.
Identities = 146/348 (42%), Positives = 209/348 (60%), Gaps = 11/348 (3%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
SLENVAFNVV KG F G +G++P ++I + + + D +F NKT+LP NVAFEL+AK
Sbjct 6071 SLENVAFNVVKKGAFTGLKGDLPTAVIADKIMVRDGPTDKCIFTNKTSLPTNVAFELYAK 6130
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
R + P + IL NLGV V+WDY+ + P T VCS TD+ + +
Sbjct 6131 RKLGLTPPLTILRNLGVVATYKFVLWDYEAECPFSNFTKQVCSYTDLDSE--------VV 6182
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNY-Y 179
FD + G + F ++ VLI+ +VKGL ++ + LN + + K Y Y
Sbjct 6183 TCFDNSIAGSFERFTTTKDAVLISNNAVKGLS-AIKLQYGFLNDLPVSTVGNKPVTWYIY 6241
Query 180 KKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGD 239
+ +G + ++Y+T R + FKPRS ME DFL + FI++Y LE Y FEH+V+GD
Sbjct 6242 VRKNGEYVEQIDSYYTHGRTFETFKPRSTMEEDFLSMDTTLFIQKYGLEDYGFEHVVFGD 6301
Query 240 FSHSQLGGLHLLIGLAKRFKESPFELEDFI-PMDSTVKNYFITDAQTGSSKCVCSVIDLL 298
S + +GG+HLLI + K F +++F+ DST+K+ IT A SSK VC+ +D+L
Sbjct 6302 VSKTTIGGMHLLISQVRLAKMGLFSVQEFMTNSDSTLKSCCITYADDPSSKNVCTYMDIL 6361
Query 299 LDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
LDDFV IIKS DL+VVSKVV V +D +MLWC++ ++TFYP+LQ
Sbjct 6362 LDDFVTIIKSLDLNVVSKVVDVIVDCKAWRWMLWCENSQIKTFYPQLQ 6409
>sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=rep
PE=3 SV=1
Length=6629
Score = 385 bits (988), Expect = 3e-120, Method: Composition-based stats.
Identities = 136/351 (39%), Positives = 196/351 (56%), Gaps = 18/351 (5%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
S++N+A+N+ GH+D GE+P I + V+ GV+ +F N+TTLP +VAFEL+AK
Sbjct 5990 SIDNIAYNMYKGGHYDAIAGEMPTVITGDKVFVIDQGVEKAVFVNQTTLPTSVAFELYAK 6049
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
RNI+ +P +IL LGVD+ VIWDY P + +T+ VC+ TDI L
Sbjct 6050 RNIRTLPNNRILKGLGVDVTNGFVIWDYANQTPLYRNTVKVCAYTDIEPN-------GLV 6102
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL-NGVTLIGEAVKTQFNYY 179
V +D R G F A N VL++ K P + NG+ L A Y
Sbjct 6103 VLYDDRY-GDYQSFLAADNAVLVSTQCYKRYSYVEIPSNLLVQNGMPLKDGA---NLYVY 6158
Query 180 KKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGD 239
K+V+G LP T TQ R+ + F+PRS +E DFL ++ + F+ERY + +HI+YG+
Sbjct 6159 KRVNGAFVTLPNTINTQGRSYETFEPRSDIERDFLAMSEESFVERYG-KDLGLQHILYGE 6217
Query 240 FSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLL 299
QLGGLH +IG+ + + + + DS V + + GS K VC+V+DLLL
Sbjct 6218 VDKPQLGGLHTVIGMYRLLRANKLNAKSVTNSDSDVMQNYFVLSDNGSYKQVCTVVDLLL 6277
Query 300 DDFV----EIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DDF+ I+K + SKVV V+IDY I+FM W +DG ++T YP+LQ
Sbjct 6278 DDFLELLRNILKEYGTN-KSKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQ 6327
>sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=rep PE=1
SV=1
Length=6629
Score = 385 bits (988), Expect = 3e-120, Method: Composition-based stats.
Identities = 136/351 (39%), Positives = 196/351 (56%), Gaps = 18/351 (5%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
S++N+A+N+ GH+D GE+P I + V+ GV+ +F N+TTLP +VAFEL+AK
Sbjct 5990 SIDNIAYNMYKGGHYDAIAGEMPTVITGDKVFVIDQGVEKAVFVNQTTLPTSVAFELYAK 6049
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
RNI+ +P +IL LGVD+ VIWDY P + +T+ VC+ TDI L
Sbjct 6050 RNIRTLPNNRILKGLGVDVTNGFVIWDYANQTPLYRNTVKVCAYTDIEPN-------GLV 6102
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL-NGVTLIGEAVKTQFNYY 179
V +D R G F A N VL++ K P + NG+ L A Y
Sbjct 6103 VLYDDRY-GDYQSFLAADNAVLVSTQCYKRYSYVEIPSNLLVQNGMPLKDGA---NLYVY 6158
Query 180 KKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGD 239
K+V+G LP T TQ R+ + F+PRS +E DFL ++ + F+ERY + +HI+YG+
Sbjct 6159 KRVNGAFVTLPNTINTQGRSYETFEPRSDIERDFLAMSEESFVERYG-KDLGLQHILYGE 6217
Query 240 FSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLL 299
QLGGLH +IG+ + + + + DS V + + GS K VC+V+DLLL
Sbjct 6218 VDKPQLGGLHTVIGMYRLLRANKLNAKSVTNSDSDVMQNYFVLSDNGSYKQVCTVVDLLL 6277
Query 300 DDFV----EIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DDF+ I+K + SKVV V+IDY I+FM W +DG ++T YP+LQ
Sbjct 6278 DDFLELLRNILKEYGTN-KSKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQ 6327
>sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=rep PE=1 SV=1
Length=6631
Score = 375 bits (962), Expect = 1e-116, Method: Composition-based stats.
Identities = 135/351 (38%), Positives = 196/351 (56%), Gaps = 18/351 (5%)
Query 1 SLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAK 60
S++N+A+N+ GH+D GE+P + + V+ GV+ +F N+T LP +VAFEL+AK
Sbjct 5992 SIDNIAYNMYKGGHYDAIAGEMPTIVTGDKVFVIDQGVEKAVFFNQTILPTSVAFELYAK 6051
Query 61 RNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLT 120
RNI+ +P +IL LGVD+ VIWDY P + +T+ VC+ TDI L
Sbjct 6052 RNIRTLPNNRILKGLGVDVTNGFVIWDYTNQTPLYRNTVKVCAYTDIEPN-------GLI 6104
Query 121 VFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL-NGVTLIGEAVKTQFNYY 179
V +D R G F A N VL++ K P + NG+ L A Y
Sbjct 6105 VLYDDRY-GDYQSFLAADNAVLVSTQCYKRYSYVEIPSNLLVQNGIPLKDGA---NLYVY 6160
Query 180 KKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGD 239
K+V+G LP T TQ R+ + F+PRS +E DFL+++ + F+E+Y E +HI+YG+
Sbjct 6161 KRVNGAFVTLPNTLNTQGRSYETFEPRSDVERDFLDMSEESFVEKYGKE-LGLQHILYGE 6219
Query 240 FSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLL 299
QLGGLH +IG+ + + + + DS V + A GS K VC+V+DLLL
Sbjct 6220 VDKPQLGGLHTVIGMCRLLRANKLNAKSVTNSDSDVMQNYFVLADNGSYKQVCTVVDLLL 6279
Query 300 DDFV----EIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
DDF+ I+K + SKVV V+IDY I+FM W +DG ++T YP+LQ
Sbjct 6280 DDFLELLRNILKEYGTN-KSKVVTVSIDYHSINFMAWFEDGIIKTCYPQLQ 6329
>sp|P18457|R1AB_CVPFS Replicase polyprotein 1ab (Fragment) OS=Porcine
transmissible gastroenteritis coronavirus (strain FS772/70)
OX=11150 GN=rep PE=3 SV=1
Length=533
Score = 276 bits (705), Expect = 2e-87, Method: Composition-based stats.
Identities = 98/232 (42%), Positives = 143/232 (62%), Gaps = 3/232 (1%)
Query 117 APLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQF 176
+ + FD + G + F R+ VLI+ +VKGL ++ + LN + + K
Sbjct 3 SEVVTCFDNSIAGSFERFTTTRDAVLISNNAVKGLS-AIKLQYGLLNDLPVSTVGNKPVT 61
Query 177 NY-YKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHI 235
Y Y + +G + ++Y+TQ R + FKPRS ME DFL + FI++Y LE Y FEH+
Sbjct 62 WYIYVRKNGEYVEQIDSYYTQGRTFETFKPRSTMEEDFLSMDTTLFIQKYGLEDYGFEHV 121
Query 236 VYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFI-PMDSTVKNYFITDAQTGSSKCVCSV 294
V+GD S + +GG+HLLI + K F +++F+ DST+K+ IT A SSK VC+
Sbjct 122 VFGDVSKTTIGGMHLLISQVRLAKMGLFSVQEFMNNSDSTLKSCCITYADDPSSKNVCTY 181
Query 295 IDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
+D+LLDDFV IIKS DL+VVSKVV V +D +MLWC++ H++TFYP+LQ
Sbjct 182 MDILLDDFVTIIKSLDLNVVSKVVDVIVDCKAWKWMLWCENSHIKTFYPQLQ 233
>sp|P12723|R1AB_IBVK Replicase polyprotein 1ab (Fragment) OS=Avian
infectious bronchitis virus (strain KB8523) OX=11126 GN=rep
PE=3 SV=1
Length=521
Score = 211 bits (536), Expect = 1e-62, Method: Composition-based stats.
Identities = 83/222 (37%), Positives = 125/222 (56%), Gaps = 8/222 (4%)
Query 129 GQVDLFRNARNGVLITEGSVKGLQPSVGPKQASL-NGVTLIGEAVKTQFNYYKKVDGVVQ 187
G F A N VL++ K P + NG++L A YK+V+G
Sbjct 2 GGGQSFLAADNAVLVSTQCYKRHSYVEIPSNLLVQNGMSLKDGA---NLYVYKRVNGAFV 58
Query 188 QLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGG 247
LP T TQ R+ + F+PRS +E DFL+++ ++F+E+Y + +HI+YG+ QLGG
Sbjct 59 TLPNTLNTQGRSYETFEPRSDVERDFLDMSEEDFVEKYG-KDLGLQHILYGEVDKPQLGG 117
Query 248 LHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEI-- 305
LH +IG+ + + + + DS V + A GS K VC+V+DLLLDDF+E+
Sbjct 118 LHTVIGMYRLLRANKLNAKSVTNSDSDVMQNYFVLADNGSYKQVCTVVDLLLDDFLELLR 177
Query 306 -IKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
I ++ + SKVV V+IDY I+FM W +DG ++T YP+LQ
Sbjct 178 NILNEYGTNKSKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQ 219
>sp|A6YQT5|RPOA_PRRSV Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus OX=28344 PE=1 SV=2
Length=3931
Score = 153 bits (386), Expect = 9e-40, Method: Composition-based stats.
Identities = 50/217 (23%), Positives = 85/217 (39%), Gaps = 38/217 (18%)
Query 136 NARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAV------KTQFNYYKKVDGVVQQL 189
+N + V L+P +A + ++G +V + K V G Q L
Sbjct 3594 TTQNNERWPDRLVASLRPIHKYSRACIGAGYMVGPSVFLGTPGVVSYYLTKFVRGEAQVL 3653
Query 190 PETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLH 249
PET F+ R +E+D E D ER E + H GD + +GG H
Sbjct 3654 PETVFSTGR----------IEVDCREYLDDR--EREVAE--SLPHAFIGDVKGTTVGGCH 3699
Query 250 LLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQ 309
+ L F+P +S + + ++K VC++ D+ L D + +
Sbjct 3700 HVTSKY---------LPRFLPKESVAVVGVSSPGK--AAKAVCTLTDVYLPDLEAYLHPE 3748
Query 310 DLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
S+ KV +D+ E+ M+W +T Y +L+
Sbjct 3749 ---TQSRCWKVMLDFKEVRLMVW----KDKTAYFQLE 3778
>sp|Q8B912|RPOA_PRRSB Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain HB-1) OX=300563
GN=rep PE=2 SV=3
Length=3961
Score = 151 bits (381), Expect = 5e-39, Method: Composition-based stats.
Identities = 50/217 (23%), Positives = 84/217 (39%), Gaps = 38/217 (18%)
Query 136 NARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAV------KTQFNYYKKVDGVVQQL 189
+N + V L+P +A + ++G +V + K V G Q L
Sbjct 3624 TTQNNERWPDRLVASLRPIHKYSRACIGAGYMVGPSVFLGTPGVVSYYLTKFVRGEAQVL 3683
Query 190 PETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLH 249
PET F+ R +E+D E D ER E + H GD + +GG H
Sbjct 3684 PETVFSTGR----------IEVDCREYLDDR--EREVAE--SLPHAFIGDVKGTTVGGCH 3729
Query 250 LLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQ 309
+ L F+P +S + + ++K C++ D+ L D + +
Sbjct 3730 HVTSKY---------LPRFLPKESVAVVGVSSPGE--AAKAFCTLTDVYLPDLEAYLHPE 3778
Query 310 DLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
SK KV +D+ E+ M+W +T Y +L+
Sbjct 3779 ---TQSKCWKVMLDFKEVRLMVW----KGKTAYFQLE 3808
>sp|Q9YN02|RPOA_PRRS1 Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain 16244B) OX=300561
GN=rep PE=1 SV=3
Length=3961
Score = 144 bits (363), Expect = 1e-36, Method: Composition-based stats.
Identities = 46/217 (21%), Positives = 83/217 (38%), Gaps = 38/217 (18%)
Query 136 NARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAV------KTQFNYYKKVDGVVQQL 189
+N + V L+P +A + ++G +V + K V G Q L
Sbjct 3624 TTQNNEKWPDRLVASLRPIHKYSRACIGAGYMVGPSVFLGTPGVVSYYLTKFVKGEAQLL 3683
Query 190 PETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLH 249
PET F+ R +E+D E D R + + H GD + +GG H
Sbjct 3684 PETVFSTGR----------IEVDCREYLDD----REREVAASLPHAFIGDVKGTTVGGCH 3729
Query 250 LLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQ 309
+ L +P +S + + ++K +C++ D+ L D + +
Sbjct 3730 HVTSRY---------LPRVLPKESVAVVGVSSPGK--AAKALCTLTDVYLPDLEAYLHPE 3778
Query 310 DLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
SK K+ +D+ E+ M+W +T Y +L+
Sbjct 3779 ---TQSKCWKMMLDFKEVRLMVW----RDKTAYFQLE 3808
>sp|Q9WJB2|RPOA_PRRSR Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain VR-2332) OX=300559
GN=rep PE=1 SV=2
Length=3960
Score = 143 bits (360), Expect = 3e-36, Method: Composition-based stats.
Identities = 46/217 (21%), Positives = 84/217 (39%), Gaps = 38/217 (18%)
Query 136 NARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAV------KTQFNYYKKVDGVVQQL 189
+ +N + V L+P +A + ++G +V + K V G Q L
Sbjct 3623 STQNNEKWPDRLVASLRPIHKYSRACIGAGYMVGPSVFLGTPGVVSYYLTKFVKGGAQVL 3682
Query 190 PETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLH 249
PET F+ R +E+D E D R + + H GD + +GG H
Sbjct 3683 PETVFSTGR----------IEVDCREYLDD----REREVAASLPHGFIGDVKGTTVGGCH 3728
Query 250 LLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQ 309
+ L +P +S + + ++K +C++ D+ L D + +
Sbjct 3729 HVTSRY---------LPRVLPKESVAVVGVSSPGK--AAKALCTLTDVYLPDLEAYLHPE 3777
Query 310 DLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
SK K+ +D+ E+ M+W +T Y +L+
Sbjct 3778 ---TQSKCWKMMLDFKEVRLMVW----KDKTAYFQLE 3807
>sp|P19811|RPOA_EAVBU Replicase polyprotein 1ab OS=Equine arteritis
virus (strain Bucyrus) OX=299386 GN=rep PE=1 SV=3
Length=3175
Score = 137 bits (346), Expect = 2e-34, Method: Composition-based stats.
Identities = 48/207 (23%), Positives = 79/207 (38%), Gaps = 33/207 (16%)
Query 138 RNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQS 197
N + IT V L V + V T + + VDG + LP++ F+
Sbjct 2882 PNCLQITLQQVCELSKPCSAGYMVGQSVFVQTPGV-TSYWLTEWVDGKARALPDSLFSSG 2940
Query 198 RNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKR 257
R F+ S+ FL+ A ++F A H G+ + S +GG H +
Sbjct 2941 R----FETNSRA---FLDEAEEKFAA-------AHPHACLGEINKSTVGGSHFIFSQY-- 2984
Query 258 FKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKV 317
L +P D+ + ++K CSV+D+ F + + L S+V
Sbjct 2985 -------LPPLLPADAVALVGASLAGK--AAKAACSVVDVYAPSFEPYLHPETL---SRV 3032
Query 318 VKVTIDYTEISFMLWCKDGHVETFYPK 344
K+ ID+ M+W TFY +
Sbjct 3033 YKIMIDFKPCRLMVWRN----ATFYVQ 3055
>sp|P0C6V8|R1AB_BRV1 Replicase polyprotein 1ab OS=Breda virus
1 OX=360393 GN=rep PE=2 SV=1
Length=6733
Score = 134 bits (338), Expect = 2e-33, Method: Composition-based stats.
Identities = 50/188 (27%), Positives = 87/188 (46%), Gaps = 26/188 (14%)
Query 164 GVTLIGEAVKTQFNYYKKVDG--VVQQLPETYFTQSRNLQ-EFKPRSQMEIDFLELAMDE 220
V + EA Q YY ++ +++LPET F+ R E P + +LA++
Sbjct 6300 SVHIYVEATGEQPLYYLQLGNGESLRELPETLFSTGRLYNLEHDPSKNFNVQ--QLAIET 6357
Query 221 FIERYKLEGYAFEHIVYGDFS--HSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNY 278
+ + H+ GDF+ + +GG+H ++ L +K S + VK
Sbjct 6358 IPKNH--------HVFAGDFTDVGTDIGGVHHVVAL-NGYKGSIIP--------NYVKPI 6400
Query 279 FITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV-VSKVVKVTIDYTEISFMLWCK-DG 336
G S +++D+ + E +K Q V VSKV+ V ID+ E+ FM++ K +
Sbjct 6401 ATGLINVGRSVKRTTLVDVCANQLYEKVKQQIAGVKVSKVIFVNIDFQEVQFMVFAKGED 6460
Query 337 HVETFYPK 344
++TFYP+
Sbjct 6461 DIQTFYPQ 6468
>sp|P0C6V7|R1AB_BEV Replicase polyprotein 1ab OS=Berne virus OX=11156
GN=rep PE=1 SV=1
Length=6857
Score = 122 bits (307), Expect = 3e-29, Method: Composition-based stats.
Identities = 44/188 (23%), Positives = 82/188 (44%), Gaps = 26/188 (14%)
Query 164 GVTLIGEAVKTQFNYYKK--VDGVVQQLPETYFTQSRNLQ-EFKPRSQMEIDFLELAMDE 220
V + EA Q YY + + +LP+T F+ R + + +LA++
Sbjct 6424 SVHIYIEATGEQPLYYLQQGKGESLFELPDTLFSTGRLYNLDHDAAQNFNVK--QLAIET 6481
Query 221 FIERYKLEGYAFEHIVYGDFS--HSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNY 278
+ H+ GDF+ + +GG+H ++ L +K S + VK
Sbjct 6482 MPNNH--------HVFSGDFTEVGTDIGGVHHVVAL-NGYKGSIIP--------NYVKPI 6524
Query 279 FITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV-VSKVVKVTIDYTEISFMLWCK-DG 336
G + +++D+ + E +K Q V VSKV+ V ID+ ++ FM++ +
Sbjct 6525 ATGLINVGRAVKRTTLVDVCANQLYEKVKQQLEGVKVSKVIFVNIDFQDVQFMVFANGED 6584
Query 337 HVETFYPK 344
++TFYP+
Sbjct 6585 DIQTFYPQ 6592
>sp|Q68772|RPOA_SHFV Replicase polyprotein 1ab OS=Simian hemorrhagic
fever virus OX=38143 GN=rep PE=2 SV=4
Length=3595
Score = 112 bits (279), Expect = 1e-25, Method: Composition-based stats.
Identities = 39/207 (19%), Positives = 72/207 (35%), Gaps = 32/207 (15%)
Query 138 RNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQS 197
N ++++ + L + +G T + K +DG + ++ ++
Sbjct 3243 PNRLVVSATRLSPLSHPAVCAGYYVGDSLFVGTPNVTSYWLTKFLDGRAVPMEDSVYSTG 3302
Query 198 RNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKR 257
R + D+L+ A +F ++ H GD + +GG H +
Sbjct 3303 RFEMDI-------RDYLDSAERDFAAKH-------PHAFIGDTKGTTVGGCHHITSQY-- 3346
Query 258 FKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKV 317
L +P DS VK + K +C+V D+ L SKV
Sbjct 3347 -------LPHVLPADSVVKVGVSKPG--VAHKALCTVTDIYLPMLGSYTSP---PTQSKV 3394
Query 318 VKVTIDYTEISFMLWCKDGHVETFYPK 344
KV +D+ M+W +T Y +
Sbjct 3395 YKVNVDHKACKLMVW----RDQTMYFQ 3417
>sp|Q04561|RPOA_PRRSL Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain Lelystad) OX=11049
GN=rep PE=1 SV=3
Length=3855
Score = 110 bits (275), Expect = 4e-25, Method: Composition-based stats.
Identities = 36/209 (17%), Positives = 72/209 (34%), Gaps = 39/209 (19%)
Query 145 EGSVKGLQPS-VGPKQASLNGVTLIGEAV------KTQFNYYKKVDGVVQQLPETYFTQS 197
+ V ++P + + ++G + + + G Q LPET +
Sbjct 3527 DRLVASMRPIDARYSKPMVGAGYVVGPSTFLGTPGVVSYYLTLYIRGEPQALPETLVSTG 3586
Query 198 RNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKR 257
R + D E + H GD + +GG H +
Sbjct 3587 R----------IATDCREYLDAA----EEEAAKELPHAFIGDVKGTTVGGCHHITSKY-- 3630
Query 258 FKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKV 317
L +P DS + + ++K VC++ D+ L + ++ + SK
Sbjct 3631 -------LPRSLPKDSVAVVGVSSPGR--AAKAVCTLTDVYLPELRPYLQPETA---SKC 3678
Query 318 VKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
K+ +D+ ++ M+W T Y +L+
Sbjct 3679 WKLKLDFRDVRLMVW----KGATAYFQLE 3703
>sp|A0MD28|RPOA_PRRSS Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (isolate Pig/United
States/SD 01-08/2001) OX=857306 PE=1 SV=2
Length=3838
Score = 108 bits (271), Expect = 1e-24, Method: Composition-based stats.
Identities = 35/209 (17%), Positives = 72/209 (34%), Gaps = 39/209 (19%)
Query 145 EGSVKGLQPS-VGPKQASLNGVTLIGEAV------KTQFNYYKKVDGVVQQLPETYFTQS 197
+ V ++P + + ++G + + + G Q LPET +
Sbjct 3510 DRLVASMRPIDARYSKPMVGAGYVVGPSTFLGTPGVVSYYLTLYIRGEPQALPETLVSTG 3569
Query 198 RNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKR 257
R + D E + H GD + +GG H +
Sbjct 3570 R----------IATDCREYLDAA----EEEAAKELPHAFIGDVKGTTVGGCHHITSKY-- 3613
Query 258 FKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKV 317
L +P DS + + ++K +C++ D+ L + ++ + SK
Sbjct 3614 -------LPRTLPKDSVAVVGVSSPGR--AAKAMCTLTDVYLPELRPYLQPETA---SKC 3661
Query 318 VKVTIDYTEISFMLWCKDGHVETFYPKLQ 346
K+ +D+ ++ M+W T Y +L+
Sbjct 3662 WKLKLDFRDVRLMVW----KGATAYFQLE 3686
>sp|Q06502|RPOA_LDVC Replicase polyprotein 1ab OS=Lactate dehydrogenase
elevating virus (strain C) OX=300015 GN=rep PE=3 SV=2
Length=3637
Score = 90.1 bits (222), Expect = 3e-18, Method: Composition-based stats.
Identities = 35/203 (17%), Positives = 66/203 (33%), Gaps = 34/203 (17%)
Query 136 NARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAV------KTQFNYYKKVDGVVQQL 189
A+N + V + +A +G +V + K + G L
Sbjct 3332 TAQNRTDWPDRLVCSMSKIDKCSRAIFCAGYHVGPSVFLGVPGVVSYYLTKFLKGKPVPL 3391
Query 190 PETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLH 249
P++ + R ++L+ EF R H G+ S +GG H
Sbjct 3392 PDSLMSTGRIALNV-------REYLDEKEMEFSSR-------CPHAFIGEVKGSNVGGCH 3437
Query 250 LLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQ 309
+ L + S VK + ++K +C+V D+ L + +
Sbjct 3438 HVTSRY---------LPPVLVPGSVVKIGVSCPGK--AAKELCTVTDVYLPELDPYLNP- 3485
Query 310 DLSVVSKVVKVTIDYTEISFMLW 332
S K+ +D+ + M+W
Sbjct 3486 --PTKSMDYKLLVDFQPVKLMVW 3506
>sp|Q83017|RPOA_LDVP Replicase polyprotein 1ab OS=Lactate dehydrogenase
elevating virus (strain Plagemann) OX=300016 GN=rep
PE=1 SV=2
Length=3616
Score = 84.7 bits (208), Expect = 2e-16, Method: Composition-based stats.
Identities = 36/203 (18%), Positives = 69/203 (34%), Gaps = 34/203 (17%)
Query 136 NARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEA----VKTQFNYY--KKVDGVVQQL 189
A+N + V G+ +A +G + V +YY K + G L
Sbjct 3311 TAQNRTEWPDRLVCGMNKMDKNSRAVFCAGYYVGPSIFLGVPGVVSYYLTKYLKGESVPL 3370
Query 190 PETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLH 249
P++ + R ++L+ EF ++ G+ S +GG H
Sbjct 3371 PDSIMSTGRIRLNV-------REYLDENEIEFAKK-------CPQPFIGEVKGSNVGGCH 3416
Query 250 LLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQ 309
+ L + S VK + ++K +C+V D+ L + +
Sbjct 3417 HVTSRF---------LPPVLVPGSVVKVGVSCPGK--AAKGLCTVTDVYLPELDSYLHP- 3464
Query 310 DLSVVSKVVKVTIDYTEISFMLW 332
S K+ +D+ + M+W
Sbjct 3465 --PSKSMDYKLLVDFQPVKLMVW 3485
>sp|A6QLQ8|ENDOU_BOVIN Uridylate-specific endoribonuclease OS=Bos
taurus OX=9913 GN=ENDOU PE=2 SV=1
Length=413
Score = 35.0 bits (79), Expect = 0.87, Method: Composition-based stats.
Identities = 32/181 (18%), Positives = 58/181 (32%), Gaps = 8/181 (4%)
Query 134 FRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQ--FNYYKKVDGVVQQLPE 191
F + L ++A+ G + + Q F V+++L
Sbjct 188 FTYVNEKLFSKPTYSAFLNLLNNYQRATGRGEHFTAQELAEQDTFLREIMKTAVMKELYG 247
Query 192 TYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLL 251
Q+R E + S ++ + L + + + FEH+ G+ ++ G H
Sbjct 248 FLHQQNRYSSEQEFVSDLKNMWFGLYSR---SKEERDSSGFEHVFSGEVKKGKVTGFHNW 304
Query 252 IGLAKRFKESPFELEDFI---PMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKS 308
I + KE + I P DS + G K V S +F + S
Sbjct 305 IRFYMQEKEGLVDYYSHIYDGPWDSYPDVLAMQFNWDGYYKEVGSAFIGSSPEFEFALYS 364
Query 309 Q 309
Sbjct 365 L 365
>sp|Q9PTU6|ENDOU_PAROL Uridylate-specific endoribonuclease OS=Paralichthys
olivaceus OX=8255 GN=endou PE=2 SV=1
Length=385
Score = 34.6 bits (78), Expect = 1.4, Method: Composition-based stats.
Identities = 10/41 (24%), Positives = 16/41 (39%), Gaps = 0/41 (0%)
Query 224 RYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFE 264
K++ FEHI G+ ++ G H I + K
Sbjct 251 NNKMDSSGFEHIFAGEIKGGKVSGFHNWIQFYRLEKRGQLN 291
>sp|A8E627|ENDUD_XENLA Uridylate-specific endoribonuclease D OS=Xenopus
laevis OX=8355 GN=endou-d PE=2 SV=1
Length=305
Score = 33.8 bits (76), Expect = 1.8, Method: Composition-based stats.
Identities = 12/63 (19%), Positives = 24/63 (38%), Gaps = 1/63 (2%)
Query 203 FKPRSQMEIDFLELAMDEFIERYK-LEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKES 261
+ + + D E+ + L+ FEH+ +G+ ++ GLH + L K
Sbjct 150 YSSAASFKTDLKEMWFGLYTRTSGPLDSSGFEHVFHGEIHKGKISGLHNWVRLYLLEKSG 209
Query 262 PFE 264
Sbjct 210 QVN 212
>sp|A8E624|ENDUC_XENLA Uridylate-specific endoribonuclease C OS=Xenopus
laevis OX=8355 GN=endou-c PE=2 SV=1
Length=303
Score = 33.5 bits (75), Expect = 3.0, Method: Composition-based stats.
Identities = 10/38 (26%), Positives = 17/38 (45%), Gaps = 0/38 (0%)
Query 227 LEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFE 264
L+ FEH+ +G+ ++ GLH + L K
Sbjct 174 LDSSGFEHVFHGEIHKGKVSGLHNWVKLYLLEKSGQVN 211
>sp|Q3V188|ENDOU_MOUSE Uridylate-specific endoribonuclease OS=Mus
musculus OX=10090 GN=Endou PE=2 SV=1
Length=412
Score = 33.1 bits (74), Expect = 3.8, Method: Composition-based stats.
Identities = 23/119 (19%), Positives = 40/119 (34%), Gaps = 8/119 (7%)
Query 199 NLQEFKPRSQMEIDFLELAMDEFIERYKL-----EGYAFEHIVYGDFSHSQLGGLHLLIG 253
+ + R E +F++ + + Y + FEH+ G+ ++ G H I
Sbjct 246 SFLHHQNRYSSEQEFVDDLKNMWFGLYSRGNDEGDSSGFEHVFSGEVKKGKVTGFHNWIR 305
Query 254 LAKRFKESPFELEDFI---PMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQ 309
+ KE + P DS + G K V SV +F + S
Sbjct 306 FYLQEKEGLLDYYSHNYDGPWDSYPDVLAMQFNWDGYYKEVGSVFIGSSPEFEFALYSL 364
>sp|P47370|THIO_MYCGE Thioredoxin OS=Mycoplasma genitalium (strain
ATCC 33530 / DSM 19775 / NCTC 10195 / G37) OX=243273 GN=trxA
PE=3 SV=1
Length=102
Score = 31.2 bits (69), Expect = 4.1, Method: Composition-based stats.
Identities = 16/50 (32%), Positives = 25/50 (50%), Gaps = 5/50 (10%)
Query 28 NNTVYTK---VDGVDVELFENKTTLPVNVAFE--LWAKRNIKPVPEVKIL 72
++ + K D D+ N T+LP V FE + KR I +P+ KI+
Sbjct 48 SDAQFVKVNVDDHTDIAAAYNITSLPTIVVFENGVEKKRAIGFMPKTKII 97
>sp|A1L237|ENDUA_DANRE Uridylate-specific endoribonuclease A OS=Danio
rerio OX=7955 GN=endoua PE=2 SV=1
Length=303
Score = 31.9 bits (71), Expect = 8.4, Method: Composition-based stats.
Identities = 10/39 (26%), Positives = 17/39 (44%), Gaps = 0/39 (0%)
Query 226 KLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFE 264
KL+ FEHI G+ ++ G H + + K+
Sbjct 171 KLDSSGFEHIFVGEIKGGKVSGFHSWVQFYQCEKQGILN 209
>sp|P21128|ENDOU_HUMAN Uridylate-specific endoribonuclease OS=Homo
sapiens OX=9606 GN=ENDOU PE=1 SV=2
Length=410
Score = 31.9 bits (71), Expect = 9.6, Method: Composition-based stats.
Identities = 23/119 (19%), Positives = 39/119 (33%), Gaps = 8/119 (7%)
Query 199 NLQEFKPRSQMEIDFLELAMDEFIERYKL-----EGYAFEHIVYGDFSHSQLGGLHLLIG 253
+ + R E +F++ + + Y + FEH+ G+ ++ G H I
Sbjct 245 SFLHHQNRYGSEQEFVDDLKNMWFGLYSRGNEEGDSSGFEHVFSGEVKKGKVTGFHNWIR 304
Query 254 LAKRFKESPFELEDFI---PMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQ 309
KE + I P DS + G K V S +F + S
Sbjct 305 FYLEEKEGLVDYYSHIYDGPWDSYPDVLAMQFNWDGYYKEVGSAFIGSSPEFEFALYSL 363
>sp|A2C1G5|PSB28_PROM1 Photosystem II reaction center Psb28 protein
OS=Prochlorococcus marinus (strain NATL1A) OX=167555 GN=psb28
PE=3 SV=1
Length=113
Score = 30.4 bits (67), Expect = 9.7, Method: Composition-based stats.
Identities = 19/100 (19%), Positives = 32/100 (32%), Gaps = 10/100 (10%)
Query 47 TTLPVNVAFELWAKRNIKPVPEVKILNNL---GVDIAANT------VIWDYKR-DAPAHI 96
T + NVA + N K PE+++ NL + +YK I
Sbjct 2 TKINENVAIQFVKGENEKDQPEIRLFRNLDGKNGKAVYKFYKPTTITLTNYKSVQRMFLI 61
Query 97 STIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRN 136
+ GV S I +E + + + + F
Sbjct 62 DSEGVLSTKKIDLSISEDHVKEVKSTYSWNSEEAFERFMR 101
Lambda K H a alpha
0.318 0.137 0.394 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0419 0.140 1.90 42.6 43.6
Effective search space used: 31483955226
Database: uniprot_sprot.fasta
Posted date: Apr 3, 2024 12:05 PM
Number of letters in database: 206,678,396
Number of sequences in database: 571,282
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40